# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Chromo PF00385.24 PRP72749.1 - 4e-12 45.9 0.1 6.9e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP72749.1 - 0.15 12.2 0.2 0.29 11.4 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DDE_Tnp_4 PF13359.6 PRP72750.1 - 3e-24 85.5 0.0 3.3e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP72750.1 - 1.3e-08 34.8 0.3 9.6e-08 31.9 0.3 1.9 1 1 0 1 1 1 1 Transposase DDE domain DUF1918 PF08940.11 PRP72755.1 - 0.053 13.2 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) BBE PF08031.12 PRP72759.1 - 1.2e-09 38.1 0.3 1.8e-09 37.5 0.3 1.4 1 0 0 1 1 1 1 Berberine and berberine like RT_RNaseH PF17917.1 PRP72760.1 - 6e-68 225.8 0.0 4.3e-33 113.7 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP72760.1 - 7e-68 225.0 0.0 1.5e-32 111.6 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP72760.1 - 6.5e-26 91.2 0.3 1.2e-25 90.4 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APOC4 PF15119.6 PRP72760.1 - 0.038 14.2 3.7 6.8 7.0 0.1 3.2 3 0 0 3 3 3 0 Apolipoprotein C4 DUF727 PF05303.12 PRP72760.1 - 0.044 13.8 0.7 32 4.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF727) Integrase_H2C2 PF17921.1 PRP72761.1 - 5.1e-06 26.5 0.7 1.3e-05 25.2 0.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP72761.1 - 0.0018 18.4 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF3886 PF13025.6 PRP72761.1 - 9 6.6 13.9 18 5.6 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Ribo_biogen_C PF04034.13 PRP72762.1 - 5.5e-53 178.0 0.0 7.6e-53 177.6 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 PRP72762.1 - 2.9e-11 43.0 0.1 2.9e-11 43.0 0.1 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI FYDLN_acid PF09538.10 PRP72762.1 - 1.2 9.8 16.0 0.086 13.5 10.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Utp21 PF04192.12 PRP72763.1 - 4.2e-50 170.4 4.0 4.2e-50 170.4 4.0 1.9 1 1 1 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 PRP72763.1 - 9.8e-24 83.2 14.3 2.1e-05 25.2 0.0 9.5 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP72763.1 - 1.8e-18 66.6 0.1 6.6e-06 26.3 0.0 6.4 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP72763.1 - 3.5e-06 26.6 0.8 0.064 12.6 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 PRP72763.1 - 7.9e-06 24.8 0.4 0.24 10.0 0.0 3.9 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PRP72763.1 - 0.00076 18.3 0.2 1.3 7.7 0.0 3.5 2 2 2 4 4 4 2 Nup133 N terminal like Frtz PF11768.8 PRP72763.1 - 0.0024 16.3 0.0 1.4 7.1 0.0 2.5 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Spore_GerAC PF05504.11 PRP72763.1 - 0.036 14.3 5.0 0.1 12.8 5.0 1.7 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal OGFr_N PF04664.13 PRP72764.1 - 3e-42 144.5 0.2 1.1e-41 142.7 0.2 1.7 1 1 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region DUF2098 PF09871.9 PRP72764.1 - 0.11 12.9 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) NIF3 PF01784.18 PRP72765.1 - 2.1e-15 57.0 0.0 4.3e-15 56.0 0.0 1.3 1 1 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Dyp_perox PF04261.12 PRP72766.1 - 3.2e-45 154.5 0.0 3.8e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Meckelin PF09773.9 PRP72767.1 - 0.03 12.4 0.1 0.052 11.7 0.0 1.3 1 1 0 1 1 1 0 Meckelin (Transmembrane protein 67) Abhydrolase_1 PF00561.20 PRP72768.1 - 4.8e-15 55.9 0.0 6.5e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP72768.1 - 8.5e-10 39.6 0.0 1.3e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP72768.1 - 5.2e-09 35.7 0.0 4e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 PRP72768.1 - 0.0044 16.6 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 PRP72768.1 - 0.021 14.5 0.0 1 9.0 0.0 2.4 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 PRP72768.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.21 PRP72768.1 - 0.054 13.0 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family PIG-P PF08510.12 PRP72768.1 - 0.55 10.2 5.8 5.9 6.8 2.5 2.5 2 0 0 2 2 2 0 PIG-P DHHC PF01529.20 PRP72768.1 - 5.9 7.0 15.2 0.07 13.2 0.6 2.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase Hydrolase PF00702.26 PRP72769.1 - 1.4e-05 25.5 0.0 1.8e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PRP72769.1 - 0.0016 18.5 0.0 0.0039 17.3 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Rep_fac_C PF08542.11 PRP72769.1 - 0.0046 17.3 0.0 0.0098 16.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Hydrolase_like PF13242.6 PRP72769.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Ferritin_2 PF13668.6 PRP72770.1 - 2.8e-57 192.7 7.5 2.8e-34 118.2 2.5 2.4 2 0 0 2 2 2 2 Ferritin-like domain Lactonase PF10282.9 PRP72771.1 - 3.9e-59 200.6 0.0 6.3e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1943 PF09172.11 PRP72771.1 - 0.0084 15.4 0.4 0.016 14.4 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) DUF228 PF02989.14 PRP72771.1 - 0.077 12.8 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Lyme disease proteins of unknown function SGL PF08450.12 PRP72771.1 - 0.14 11.7 0.0 7 6.2 0.0 2.3 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region RasGAP PF00616.19 PRP72772.1 - 0.041 13.6 0.1 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Hydin_ADK PF17213.3 PRP72772.1 - 0.06 13.6 1.5 0.14 12.4 0.6 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Pkinase_Tyr PF07714.17 PRP72773.1 - 1.5e-40 139.1 0.0 2.2e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP72773.1 - 6.7e-24 84.7 0.0 1.1e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP72773.1 - 3.3e-08 33.9 9.8 9.4e-08 32.5 9.8 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Syndecan PF01034.20 PRP72773.1 - 0.017 15.0 0.2 0.039 13.9 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Ecl1 PF12855.7 PRP72773.1 - 0.053 14.7 33.1 0.18 12.9 33.1 2.0 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins SPX PF03105.19 PRP72773.1 - 0.074 13.0 14.8 0.12 12.3 14.8 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 PRP72773.1 - 0.089 11.3 9.2 0.13 10.8 9.2 1.3 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 PRP72773.1 - 0.11 11.4 12.8 0.16 10.8 12.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2663 PF10864.8 PRP72773.1 - 0.22 11.9 0.2 0.57 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Caleosin PF05042.13 PRP72775.1 - 8.8e-75 250.3 0.4 1.4e-74 249.7 0.4 1.3 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 PRP72775.1 - 1.2e-05 24.8 1.2 0.025 14.5 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 PRP72775.1 - 0.0021 17.5 2.8 1.5 8.5 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PRP72775.1 - 0.014 15.8 0.1 28 5.3 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.6 PRP72775.1 - 0.03 14.2 0.9 0.77 9.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair SANTA PF09133.10 PRP72776.1 - 3e-08 34.0 0.0 7.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 SANTA (SANT Associated) AT_hook PF02178.19 PRP72776.1 - 3.9 7.7 54.5 0.33 11.0 3.7 6.8 5 0 0 5 5 5 0 AT hook motif MBOAT PF03062.19 PRP72777.1 - 1.4e-27 97.0 18.0 2.3e-27 96.3 18.0 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 PRP72777.1 - 0.025 14.9 1.7 0.025 14.9 1.7 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Sec61_beta PF03911.16 PRP72777.1 - 0.031 14.3 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Sec61beta family PIG-Y PF15159.6 PRP72779.1 - 0.28 12.1 6.0 3.1 8.8 6.0 2.1 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y 2TM PF13239.6 PRP72779.1 - 0.28 11.5 1.8 1.2 9.5 0.0 2.4 2 1 0 2 2 2 0 2TM domain EcsB PF05975.12 PRP72779.1 - 3.7 6.3 8.4 4.5 6.0 8.4 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB LETM1 PF07766.13 PRP72780.1 - 3.9e-35 121.5 0.0 6.2e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein R3H PF01424.22 PRP72780.1 - 2.4e-12 46.6 0.1 5.9e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 PRP72780.1 - 3.9e-12 46.7 8.6 3.9e-12 46.7 8.6 4.3 4 1 0 4 4 4 1 SUZ domain Pkinase PF00069.25 PRP72782.1 - 4.5e-53 180.3 0.0 5.8e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP72782.1 - 5.5e-33 114.3 0.0 8e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP72782.1 - 1.2e-06 27.6 0.0 2.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP72782.1 - 4.1e-05 23.0 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP72782.1 - 0.0039 16.6 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF572 PF04502.13 PRP72783.1 - 8.7e-67 226.1 2.3 9.4e-67 226.0 2.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 PRP72783.1 - 0.0085 16.0 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DNA_pol_A_exo1 PF01612.20 PRP72784.1 - 5.1e-24 84.9 0.1 7.9e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-met PF12874.7 PRP72784.1 - 4.2e-05 23.8 1.5 4.2e-05 23.8 1.5 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PRP72784.1 - 0.00019 21.7 0.7 0.00019 21.7 0.7 2.3 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PRP72784.1 - 0.0027 17.9 3.0 0.0073 16.6 3.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PRP72784.1 - 0.0034 18.1 1.9 0.0034 18.1 1.9 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 PRP72784.1 - 0.037 14.5 4.0 0.037 14.5 4.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Elf1 PF05129.13 PRP72784.1 - 0.17 11.9 2.1 0.44 10.6 0.6 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-Di19 PF05605.12 PRP72784.1 - 0.26 11.6 4.2 0.39 11.1 1.9 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zf_RING PF16744.5 PRP72784.1 - 0.29 11.3 3.0 0.96 9.6 0.5 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger DUF2256 PF10013.9 PRP72784.1 - 4 7.6 9.1 18 5.6 1.9 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Sec66 PF09802.9 PRP72785.1 - 0.026 14.1 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Raptor_N PF14538.6 PRP72786.1 - 8e-64 214.0 0.0 1.6e-63 213.0 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 PRP72786.1 - 2.8e-08 33.3 8.0 0.003 17.7 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat WD40 PF00400.32 PRP72786.1 - 4.4e-08 33.6 8.5 0.25 12.3 0.2 6.8 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_2 PF13646.6 PRP72786.1 - 8.6e-07 29.3 0.6 0.0003 21.1 0.0 3.7 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 PRP72786.1 - 4.1e-06 26.9 0.0 0.0011 19.1 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PRP72786.1 - 0.0041 15.8 0.0 0.2 10.2 0.0 2.4 3 0 0 3 3 3 1 Adaptin N terminal region HEAT_EZ PF13513.6 PRP72786.1 - 0.0098 16.4 0.1 0.15 12.6 0.0 2.9 2 0 0 2 2 2 1 HEAT-like repeat Atx10homo_assoc PF09759.9 PRP72786.1 - 0.14 12.2 0.1 0.56 10.3 0.1 2.0 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Radial_spoke PF04712.12 PRP72787.1 - 3.4e-18 65.9 12.0 1.3e-08 34.2 0.0 4.7 3 1 0 3 3 3 3 Radial spokehead-like protein CRT-like PF08627.10 PRP72790.1 - 1.9e-92 309.8 17.1 3.4e-92 308.9 17.1 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like DnaJ PF00226.31 PRP72791.1 - 9.4e-21 73.7 3.6 1.6e-20 73.0 3.6 1.4 1 0 0 1 1 1 1 DnaJ domain LMBR1 PF04791.16 PRP72791.1 - 0.37 9.7 0.9 0.5 9.2 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TRAM_LAG1_CLN8 PF03798.16 PRP72793.1 - 8.2e-35 120.3 26.1 1.4e-34 119.6 26.1 1.4 1 0 0 1 1 1 1 TLC domain RabGAP-TBC PF00566.18 PRP72793.1 - 1.4e-25 90.3 9.6 1.4e-25 90.3 9.6 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Homeodomain PF00046.29 PRP72793.1 - 1e-13 50.9 2.2 1e-13 50.9 2.2 2.3 2 0 0 2 2 2 1 Homeodomain U-box PF04564.15 PRP72794.1 - 6.5e-17 61.5 0.1 1.8e-16 60.0 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 PRP72794.1 - 0.0023 17.7 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 PRP72794.1 - 0.0031 17.5 0.0 0.0073 16.3 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 PRP72794.1 - 0.0067 16.5 0.0 0.035 14.2 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Syntaxin-6_N PF09177.11 PRP72794.1 - 0.021 15.4 0.7 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal BST2 PF16716.5 PRP72794.1 - 0.024 15.2 1.9 0.024 15.2 1.9 2.0 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 HMMR_N PF15905.5 PRP72794.1 - 0.034 13.6 6.9 0.049 13.1 6.9 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal AAA_13 PF13166.6 PRP72794.1 - 0.055 12.1 2.0 0.072 11.7 2.0 1.1 1 0 0 1 1 1 0 AAA domain PspA_IM30 PF04012.12 PRP72794.1 - 0.058 13.0 6.2 0.87 9.1 6.3 2.0 1 1 0 1 1 1 0 PspA/IM30 family XhlA PF10779.9 PRP72794.1 - 0.15 12.3 11.2 0.95 9.7 1.1 3.4 2 1 1 3 3 3 0 Haemolysin XhlA ADH_N PF08240.12 PRP72795.1 - 5.8e-29 100.2 0.4 9.2e-29 99.5 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PRP72795.1 - 2.5e-09 37.2 0.4 1.3e-05 25.2 0.0 2.9 2 1 1 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 PRP72795.1 - 0.0015 18.4 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 PRP72795.1 - 0.029 13.7 0.0 0.077 12.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Beta_helix PF13229.6 PRP72796.1 - 1.7e-05 24.7 4.5 1.7e-05 24.7 4.5 2.3 2 0 0 2 2 2 2 Right handed beta helix region DUF4957 PF16318.5 PRP72796.1 - 0.028 14.3 0.4 0.093 12.7 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4957) WD40 PF00400.32 PRP72797.1 - 1.5e-25 88.9 16.5 3e-05 24.7 0.0 6.9 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP72797.1 - 3.4e-17 62.5 2.5 7.4e-05 23.0 0.1 4.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP72797.1 - 1.8e-07 31.2 0.2 0.33 10.8 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 PRP72797.1 - 0.022 13.7 1.6 1.1 8.1 0.4 2.4 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SH2 PF00017.24 PRP72798.1 - 1.4e-12 47.5 0.4 1e-11 44.8 0.1 2.7 2 0 0 2 2 2 1 SH2 domain TMF_DNA_bd PF12329.8 PRP72798.1 - 4.9e-05 23.2 3.8 4.9e-05 23.2 3.8 17.4 9 4 7 17 17 17 1 TATA element modulatory factor 1 DNA binding DUF3800 PF12686.7 PRP72798.1 - 0.0019 18.8 0.0 17 6.1 0.0 6.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3800) Phospholip_B PF04916.13 PRP72799.1 - 5.2e-155 517.0 5.7 6.4e-155 516.7 5.7 1.0 1 0 0 1 1 1 1 Phospholipase B BTB_2 PF02214.22 PRP72800.1 - 0.00012 22.3 0.0 0.00032 21.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 PRP72800.1 - 0.00084 19.4 0.0 0.027 14.6 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain DUF3342 PF11822.8 PRP72800.1 - 0.1 12.8 0.2 0.63 10.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) F-box-like PF12937.7 PRP72801.1 - 6.2e-10 38.8 0.5 1.2e-09 37.9 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP72801.1 - 3.4e-08 33.2 0.2 9.9e-08 31.7 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP72801.1 - 0.024 14.5 0.7 0.078 12.9 0.0 2.2 2 0 0 2 2 2 0 F-box Hira PF07569.11 PRP72801.1 - 0.025 14.3 0.2 1.2 8.8 0.0 2.4 2 1 0 2 2 2 0 TUP1-like enhancer of split DUF5046 PF16465.5 PRP72801.1 - 0.036 13.5 0.0 1.9 7.8 0.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) WD40 PF00400.32 PRP72801.1 - 6.5 7.8 6.7 1.4 9.9 0.1 3.5 3 1 1 4 4 4 0 WD domain, G-beta repeat Snf7 PF03357.21 PRP72802.1 - 2.2e-31 108.8 19.6 2.2e-31 108.8 19.6 2.3 2 1 1 3 3 3 1 Snf7 Aa_trans PF01490.18 PRP72803.1 - 2.8e-41 141.6 30.2 4.1e-41 141.0 30.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cytochrom_B561 PF03188.16 PRP72803.1 - 3 8.0 15.2 2.6 8.2 0.7 3.5 2 1 1 3 3 3 0 Eukaryotic cytochrome b561 IBR PF01485.21 PRP72804.1 - 6e-18 64.8 36.2 1.8e-10 40.9 10.3 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain UIM PF02809.20 PRP72804.1 - 0.0021 17.9 17.3 0.04 13.8 3.6 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-C3HC4_2 PF13923.6 PRP72804.1 - 0.0031 17.3 4.8 0.0031 17.3 4.8 4.3 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP72804.1 - 0.0059 16.6 4.2 0.0059 16.6 4.2 4.1 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 PRP72804.1 - 0.0097 16.2 4.6 0.0097 16.2 4.6 3.8 3 0 0 3 3 3 2 Ring finger domain zf-RING_4 PF14570.6 PRP72804.1 - 0.012 15.4 28.6 1.2 9.0 6.3 4.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 PRP72804.1 - 0.012 15.4 3.4 0.012 15.4 3.4 4.2 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) MRC1 PF09444.10 PRP72805.1 - 2.2e-09 38.0 23.9 2.2e-09 38.0 23.9 7.1 3 2 2 5 5 5 1 MRC1-like domain Glyco_hydro_65N PF03636.15 PRP72806.1 - 0.18 11.4 1.8 1.2 8.7 1.5 2.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_88 PF07470.13 PRP72807.1 - 4.3e-16 58.9 10.8 6.3e-16 58.4 10.8 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Sec3_C PF09763.9 PRP72808.1 - 0.15 10.4 2.0 0.21 10.0 2.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Apt1 PF10351.9 PRP72808.1 - 0.32 9.8 11.9 0.5 9.2 11.9 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain MID_MedPIWI PF18296.1 PRP72808.1 - 0.58 9.9 13.1 0.32 10.7 8.0 2.5 2 0 0 2 2 2 0 MID domain of medPIWI GCOM2 PF15328.6 PRP72808.1 - 1.7 9.0 8.1 0.15 12.4 3.0 1.7 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 CCDC106 PF15794.5 PRP72808.1 - 5.1 6.7 9.1 11 5.7 9.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 HATPase_c PF02518.26 PRP72810.1 - 6.8e-29 100.6 0.5 1.5e-28 99.5 0.5 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP72810.1 - 2.7e-15 56.5 1.5 3.8e-15 56.0 0.4 1.9 2 0 0 2 2 2 1 Response regulator receiver domain MASE3 PF17159.4 PRP72810.1 - 3.2e-08 33.5 20.9 3.2e-08 33.5 20.9 1.7 1 1 1 2 2 2 2 Membrane-associated sensor domain HisKA PF00512.25 PRP72810.1 - 6.2e-08 32.6 2.9 5.1e-07 29.6 0.1 3.2 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP72810.1 - 0.0023 17.8 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 PRP72810.1 - 0.0091 16.0 0.0 0.035 14.1 0.0 2.1 1 0 0 1 1 1 1 PAS fold RT_RNaseH_2 PF17919.1 PRP72810.1 - 0.11 12.5 0.1 5.7 7.0 0.0 2.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF1516 PF07457.11 PRP72810.1 - 0.22 11.7 3.7 0.37 11.0 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) Deltameth_res PF16020.5 PRP72817.1 - 0.48 10.3 1.5 0.51 10.3 0.0 1.8 2 0 0 2 2 2 0 Deltamethrin resistance PDR_CDR PF06422.12 PRP72820.1 - 3.4e-24 84.6 0.0 7.6e-24 83.4 0.0 1.6 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane PF01061.24 PRP72820.1 - 6.5e-18 64.9 12.2 6.5e-18 64.9 12.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PRP72820.1 - 1.8e-09 38.2 0.6 2.4e-09 37.8 0.1 1.5 2 0 0 2 2 1 1 ABC transporter RsgA_GTPase PF03193.16 PRP72820.1 - 5.7e-05 23.1 0.1 8.3e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 PRP72820.1 - 0.0003 20.4 0.1 0.00047 19.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PRP72820.1 - 0.00033 20.4 0.1 0.00071 19.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 PRP72820.1 - 0.0011 18.1 15.0 0.0025 17.0 14.8 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 PRP72820.1 - 0.017 15.5 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 PRP72820.1 - 0.023 15.2 0.2 0.047 14.2 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PRP72820.1 - 0.03 14.6 1.1 0.048 13.9 1.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PRP72820.1 - 0.031 14.6 1.4 0.04 14.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 PRP72820.1 - 0.069 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 PRP72820.1 - 0.071 13.3 1.6 0.085 13.0 0.7 1.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PRP72820.1 - 0.075 13.5 0.4 0.14 12.6 0.1 1.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 PRP72820.1 - 0.12 11.9 0.5 0.23 11.0 0.3 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 PRP72820.1 - 0.21 11.3 1.0 0.32 10.7 1.0 1.2 1 0 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 PRP72821.1 - 1.7e-58 198.0 0.2 7.3e-57 192.6 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP72821.1 - 1.2e-47 162.5 0.1 1.5e-46 158.9 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP72821.1 - 3.3e-06 26.1 0.5 4.7e-06 25.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP72821.1 - 0.00014 20.9 0.4 0.0007 18.6 0.4 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PRP72821.1 - 0.00095 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP72821.1 - 0.0027 17.1 0.5 0.0076 15.6 0.0 1.9 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family PRIMA1 PF16101.5 PRP72821.1 - 0.0073 16.3 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Syndecan PF01034.20 PRP72821.1 - 0.009 15.9 0.4 0.016 15.1 0.4 1.3 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.6 PRP72821.1 - 0.009 16.9 0.6 0.018 15.9 0.6 1.7 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain RIO1 PF01163.22 PRP72821.1 - 0.042 13.5 0.9 0.062 12.9 0.1 1.7 2 1 0 2 2 2 0 RIO1 family OPT PF03169.15 PRP72821.1 - 0.11 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein PIP49_N PF14875.6 PRP72821.1 - 0.37 10.6 1.8 1.1 9.0 1.8 1.7 1 1 0 1 1 1 0 N-term cysteine-rich ER, FAM69 FeoB_associated PF12669.7 PRP72821.1 - 0.66 10.4 3.7 2.7 8.5 3.7 1.9 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein ATP-synt_ab_C PF00306.27 PRP72822.1 - 9.5e-64 213.4 0.0 1.9e-30 105.8 0.0 2.7 3 0 0 3 3 3 2 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab PF00006.25 PRP72822.1 - 4.6e-08 33.0 0.0 8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Ribosomal_L11_N PF03946.14 PRP72822.1 - 1.7e-06 27.8 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain MGTL PF17059.5 PRP72822.1 - 2.8 7.9 11.5 38 4.3 0.4 4.0 3 0 0 3 3 3 0 MgtA leader peptide KH_8 PF17903.1 PRP72828.1 - 1.7e-26 92.1 0.0 3.6e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain 2-oxoacid_dh PF00198.23 PRP72829.1 - 1.6e-71 240.5 0.1 1.9e-71 240.2 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 PRP72829.1 - 4.1e-06 27.0 0.2 2.8e-05 24.4 0.1 2.3 2 0 0 2 2 2 1 e3 binding domain Man-6-P_recep PF02157.15 PRP72830.1 - 2.4e-08 33.4 0.1 4.9e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor DUF4690 PF15756.5 PRP72830.1 - 0.37 11.4 0.0 0.37 11.4 0.0 3.2 3 1 0 3 3 3 0 Small Novel Rich in Cartilage ATG27 PF09451.10 PRP72830.1 - 0.65 9.8 3.9 0.24 11.2 0.1 2.2 3 0 0 3 3 3 0 Autophagy-related protein 27 zf-B_box PF00643.24 PRP72831.1 - 0.00048 20.2 6.4 0.00048 20.2 6.4 2.0 1 1 1 2 2 2 1 B-box zinc finger zf_UBZ PF18439.1 PRP72831.1 - 0.37 10.4 0.0 0.37 10.4 0.0 2.7 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 PRP72831.1 - 1.2 9.2 5.7 1.4 8.9 5.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 PRP72831.1 - 2.5 8.4 13.3 0.19 12.0 6.1 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 PRP72831.1 - 9.9 6.4 14.9 4.9 7.4 8.4 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger DUF1682 PF07946.14 PRP72833.1 - 9.8e-65 218.9 13.0 1.7e-64 218.1 13.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Peptidase_S41 PF03572.18 PRP72833.1 - 2e-10 40.5 0.0 3.9e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 Peptidase family S41 TMEM154 PF15102.6 PRP72833.1 - 0.00043 20.2 0.4 0.0014 18.5 0.4 1.9 1 0 0 1 1 1 1 TMEM154 protein family RIFIN PF02009.16 PRP72833.1 - 0.0037 17.2 0.3 0.0037 17.2 0.3 2.4 2 0 0 2 2 2 1 Rifin MGC-24 PF05283.11 PRP72833.1 - 0.0093 16.4 1.5 0.03 14.8 1.5 1.9 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4690 PF15756.5 PRP72833.1 - 0.014 16.0 2.2 0.014 16.0 2.2 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Syndecan PF01034.20 PRP72833.1 - 0.071 13.0 0.5 0.19 11.7 0.5 1.7 1 0 0 1 1 1 0 Syndecan domain Mucin PF01456.17 PRP72833.1 - 0.33 10.9 13.2 9.1 6.3 12.0 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein TMEM51 PF15345.6 PRP72833.1 - 4.2 7.1 9.4 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Transmembrane protein 51 DUF1365 PF07103.11 PRP72834.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1365) Pro-kuma_activ PF09286.11 PRP72835.1 - 2.1e-25 89.7 0.0 9e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP72835.1 - 0.017 14.4 0.0 0.036 13.3 0.0 1.4 1 1 0 1 1 1 0 Subtilase family PHM7_ext PF12621.8 PRP72837.1 - 0.0032 17.6 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RT_RNaseH PF17917.1 PRP72842.1 - 6.3e-30 103.6 0.0 1.4e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP72842.1 - 7.7e-22 77.2 1.2 2.1e-21 75.8 1.2 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 PRP72842.1 - 5.6e-20 71.2 0.0 1.2e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 PRP72842.1 - 2e-15 57.0 0.1 5.5e-15 55.6 0.1 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 PRP72842.1 - 3.4e-07 30.4 0.1 8.1e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger BCS1_N PF08740.11 PRP72842.1 - 0.0009 19.3 0.3 0.69 9.9 0.0 2.5 2 0 0 2 2 2 2 BCS1 N terminal ThiD2 PF17792.1 PRP72842.1 - 0.04 14.4 0.1 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 ThiD2 family RVT_3 PF13456.6 PRP72842.1 - 0.072 12.9 0.1 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase-like Dmd PF17587.2 PRP72842.1 - 0.075 13.4 1.1 19 5.7 0.1 2.6 2 0 0 2 2 2 0 Discriminator of mRNA degradation DUF3857 PF12969.7 PRP72842.1 - 0.14 12.2 0.7 22 5.1 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) MBOAT_2 PF13813.6 PRP72842.1 - 0.18 12.1 1.2 0.53 10.6 0.2 2.2 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family DUF434 PF04256.12 PRP72844.1 - 1.1 9.0 5.1 6.7 6.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF434) NAD_binding_1 PF00175.21 PRP72845.1 - 4.5e-23 82.0 0.5 4.1e-11 43.5 0.0 2.2 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain MRP-S24 PF14955.6 PRP72845.1 - 0.026 14.5 0.0 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 NAD_binding_6 PF08030.12 PRP72845.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.6 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Evr1_Alr PF04777.13 PRP72845.1 - 0.14 12.7 1.4 27 5.3 0.1 3.1 2 1 1 3 3 3 0 Erv1 / Alr family p450 PF00067.22 PRP72846.1 - 7e-05 21.7 0.0 8.3e-05 21.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RT_RNaseH PF17917.1 PRP72850.1 - 2.2e-29 101.8 0.1 5.1e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP72850.1 - 1.6e-16 60.2 0.0 4.9e-14 52.2 0.0 2.6 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP72850.1 - 2.3e-15 56.4 0.4 5.6e-15 55.2 0.4 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP72850.1 - 2.6e-15 56.6 0.6 1e-14 54.7 0.2 2.1 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 PRP72850.1 - 0.0017 18.6 0.1 0.0035 17.5 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger MBOAT_2 PF13813.6 PRP72850.1 - 0.055 13.7 0.8 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family RVT_1 PF00078.27 PRP72856.1 - 1.8e-22 80.0 0.0 8.6e-16 58.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SHQ1 PF04925.15 PRP72856.1 - 0.005 16.4 0.8 2.6 7.6 0.1 2.4 2 0 0 2 2 2 2 SHQ1 protein Clusterin PF01093.17 PRP72856.1 - 0.0093 15.1 0.6 0.35 9.9 0.1 2.1 2 0 0 2 2 2 1 Clusterin DUF2535 PF10751.9 PRP72856.1 - 0.023 15.2 4.2 3.7 8.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) Mob1_phocein PF03637.17 PRP72856.1 - 0.029 14.4 2.4 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Mob1/phocein family MP PF01107.18 PRP72856.1 - 0.11 12.0 0.2 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Viral movement protein (MP) DUF4306 PF14154.6 PRP72856.1 - 1.7 8.8 4.2 9.2 6.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4306) DUF4437 PF14499.6 PRP72857.1 - 0.0023 17.1 0.1 0.0026 16.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Chromo PF00385.24 PRP72858.1 - 5.2e-14 51.9 0.0 6.7e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP72858.1 - 0.016 15.4 0.7 0.03 14.5 0.7 1.6 1 1 0 1 1 1 0 Polycomb-like MTF2 factor 2 bPH_6 PF10756.9 PRP72858.1 - 0.061 13.4 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain Ank_2 PF12796.7 PRP72861.1 - 9e-47 157.6 0.0 1.1e-11 45.1 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP72861.1 - 5.2e-30 103.4 4.9 1.3e-06 28.8 0.0 6.4 3 1 5 8 8 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP72861.1 - 3.1e-22 76.2 0.2 0.26 12.0 0.0 9.3 8 1 1 9 9 9 4 Ankyrin repeat Ank PF00023.30 PRP72861.1 - 1.8e-20 72.4 6.6 0.51 10.9 0.0 9.3 8 1 1 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 PRP72861.1 - 6.8e-19 67.7 1.0 0.013 15.8 0.0 8.1 3 2 6 9 9 9 5 Ankyrin repeats (many copies) DUF1403 PF07183.11 PRP72861.1 - 0.00034 20.3 3.4 2.5 7.6 0.0 4.8 2 1 4 6 6 6 2 Protein of unknown function (DUF1403) BiPBP_C PF06832.12 PRP72861.1 - 0.00047 20.1 0.4 5.5 7.1 0.1 4.1 2 1 3 5 5 5 1 Penicillin-Binding Protein C-terminus Family DNA_photolyase PF00875.18 PRP72861.1 - 0.0052 16.8 10.1 7.6 6.5 0.4 5.1 1 1 5 6 6 6 2 DNA photolyase DUF3734 PF12536.8 PRP72861.1 - 0.024 15.0 0.9 3.2 8.1 0.1 3.7 1 1 1 3 3 3 0 Patatin phospholipase Methyltransf_24 PF13578.6 PRP72861.1 - 0.027 15.5 5.1 9.3 7.3 0.5 3.7 1 1 1 2 2 2 0 Methyltransferase domain VapB_antitoxin PF09957.9 PRP72861.1 - 0.031 14.2 0.5 43 4.1 0.0 4.2 4 0 0 4 4 4 0 Bacterial antitoxin of type II TA system, VapB DNA_pol3_tau_4 PF12168.8 PRP72861.1 - 0.055 14.0 0.2 2.9 8.5 0.0 2.4 1 1 1 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding DUF4350 PF14258.6 PRP72861.1 - 0.076 13.5 0.7 7.9 7.0 0.0 3.4 2 1 1 4 4 4 0 Domain of unknown function (DUF4350) Malate_DH PF12434.8 PRP72861.1 - 0.27 11.3 1.3 88 3.3 0.0 3.8 3 0 0 3 3 3 0 Malate dehydrogenase enzyme Antimicrobial19 PF08225.11 PRP72861.1 - 6.8 6.4 18.9 1.3 8.7 0.4 5.1 5 0 0 5 5 5 0 Pseudin antimicrobial peptide Trp_dioxygenase PF03301.13 PRP72863.1 - 0.032 13.6 0.2 0.037 13.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase Phage_Mu_Gam PF07352.12 PRP72864.1 - 0.069 13.1 13.4 2.7 7.9 4.8 3.2 2 1 2 4 4 4 0 Bacteriophage Mu Gam like protein Noelin-1 PF12308.8 PRP72864.1 - 0.75 9.8 6.8 0.82 9.7 1.7 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein ATP-synt_F6 PF05511.11 PRP72864.1 - 2.2 8.8 5.2 2.3 8.7 2.2 2.5 1 1 2 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 DUF829 PF05705.14 PRP72865.1 - 0.0001 22.3 0.2 0.036 14.0 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Torus PF16131.5 PRP72867.1 - 7.5e-05 23.4 0.0 0.00019 22.1 0.0 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 PRP72867.1 - 0.0001 22.0 4.6 0.00014 21.5 4.6 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PRP72867.1 - 0.0002 21.3 5.6 0.00031 20.7 5.6 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PRP72867.1 - 0.0014 18.5 6.7 0.0024 17.7 6.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIA PF03153.13 PRP72867.1 - 0.023 14.7 12.3 0.027 14.5 12.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 PRP72867.1 - 5.3 5.2 9.9 5.8 5.1 9.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AIG1 PF04548.16 PRP72869.1 - 0.073 12.4 0.0 0.077 12.3 0.0 1.0 1 0 0 1 1 1 0 AIG1 family Iron_traffic PF04362.14 PRP72870.1 - 0.095 12.4 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking RT_RNaseH_2 PF17919.1 PRP72872.1 - 2.2e-31 107.9 0.0 2.9e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PRP72872.1 - 1.1e-29 102.8 0.0 1.4e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP72873.1 - 6e-28 97.9 0.1 1.3e-27 96.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DinI PF06183.13 PRP72879.1 - 1.1e-05 25.6 0.0 2.1 8.8 0.0 3.8 2 1 1 3 3 3 2 DinI-like family Flp_N PF03930.14 PRP72879.1 - 0.00012 22.0 1.5 3 7.9 0.0 4.9 5 0 0 5 5 5 1 Recombinase Flp protein N-terminus PACT_coil_coil PF10495.9 PRP72879.1 - 0.0041 17.7 0.1 26 5.5 0.0 3.4 3 0 0 3 3 3 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein MCD_N PF17408.2 PRP72879.1 - 0.016 15.3 2.6 0.068 13.3 0.2 3.1 3 1 1 4 4 4 0 Malonyl-CoA decarboxylase N-terminal domain HA PF03457.14 PRP72879.1 - 0.017 15.5 0.5 0.042 14.2 0.5 1.7 1 0 0 1 1 1 0 Helicase associated domain Med25 PF11232.8 PRP72879.1 - 0.019 14.9 0.3 0.056 13.4 0.3 1.8 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 UPA PF17217.3 PRP72879.1 - 0.026 14.4 0.3 5.4 6.9 0.1 2.8 2 0 0 2 2 2 0 UPA domain PIN_2 PF10130.9 PRP72879.1 - 0.081 13.2 0.2 60 3.9 0.0 3.5 3 0 0 3 3 3 0 PIN domain zf-C2H2_4 PF13894.6 PRP72879.1 - 0.17 12.8 4.5 0.61 11.1 1.9 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1640 PF07798.11 PRP72879.1 - 0.17 11.9 2.4 0.24 11.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) zf-C2H2_11 PF16622.5 PRP72879.1 - 0.27 11.0 3.5 27 4.6 0.1 3.6 3 0 0 3 3 3 0 zinc-finger C2H2-type PdaC PF13739.6 PRP72879.1 - 6.7 7.8 10.6 9.1 7.3 0.5 3.8 4 0 0 4 4 3 0 Deacetylase PdaC rve PF00665.26 PRP72880.1 - 0.0019 18.4 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain GPS PF01825.21 PRP72882.1 - 3.1e-11 43.6 7.4 6.7e-11 42.5 7.4 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Keratin_B2 PF01500.17 PRP72882.1 - 0.043 13.8 10.3 0.17 11.9 4.8 2.2 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein Mucin PF01456.17 PRP72882.1 - 0.062 13.3 32.0 0.12 12.3 32.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein SesA PF17107.5 PRP72882.1 - 0.063 13.5 0.0 1.8 8.7 0.0 2.3 1 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2608 PF11019.8 PRP72882.1 - 0.063 12.8 1.9 0.11 12.0 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) VPDSG-CTERM PF18205.1 PRP72882.1 - 0.33 10.8 2.4 0.69 9.8 2.4 1.6 1 0 0 1 1 1 0 VPDSG-CTERM motif Sporozoite_P67 PF05642.11 PRP72882.1 - 0.49 8.4 9.5 0.7 7.9 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM154 PF15102.6 PRP72882.1 - 0.86 9.5 12.8 44 4.0 0.0 2.7 2 0 0 2 2 2 0 TMEM154 protein family DUF515 PF04415.12 PRP72882.1 - 2.4 6.5 8.1 3.7 5.8 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Macoilin PF09726.9 PRP72882.1 - 3.6 6.0 5.1 5 5.6 5.1 1.1 1 0 0 1 1 1 0 Macoilin family UcrQ PF02939.16 PRP72883.1 - 0.12 12.3 0.3 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 UcrQ family DUF1758 PF05585.12 PRP72885.1 - 0.0015 18.3 0.1 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 PRP72885.1 - 0.0016 18.9 0.0 0.0042 17.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PRP72885.1 - 0.0017 19.0 0.0 0.0048 17.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease GPS2_interact PF15784.5 PRP72885.1 - 0.0026 18.2 1.8 0.031 14.7 0.8 2.7 2 0 0 2 2 2 1 G-protein pathway suppressor 2-interacting domain RNAse_A_bac PF18431.1 PRP72886.1 - 3.8e-18 66.5 0.2 1.2e-17 64.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial CdiA-CT RNAse A domain CdiI_2 PF18593.1 PRP72886.1 - 4.8e-15 56.0 0.7 1.4e-14 54.4 0.7 1.9 1 0 0 1 1 1 1 CdiI immunity protein OCRE PF17780.1 PRP72886.1 - 0.056 13.5 1.2 0.056 13.5 1.2 2.0 2 0 0 2 2 2 0 OCRE domain Integrase_H2C2 PF17921.1 PRP72887.1 - 8.9e-57 189.1 14.4 8.7e-22 77.0 1.1 3.7 3 0 0 3 3 3 3 Integrase zinc binding domain rve PF00665.26 PRP72887.1 - 1.5e-39 134.9 4.9 9.4e-15 54.9 0.1 4.0 4 0 0 4 4 3 3 Integrase core domain RT_RNaseH_2 PF17919.1 PRP72887.1 - 1e-27 96.1 0.0 2.3e-27 95.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PRP72887.1 - 7.1e-20 71.2 0.0 2.5e-19 69.5 0.0 1.9 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 PRP72887.1 - 9.1e-19 67.4 4.8 1.3e-06 28.5 0.1 3.6 3 0 0 3 3 3 3 H2C2 zinc finger Ferrochelatase PF00762.19 PRP72887.1 - 1.8e-06 27.3 0.2 0.69 8.9 0.1 3.2 3 0 0 3 3 3 3 Ferrochelatase P63C PF10546.9 PRP72887.1 - 8e-05 23.2 2.0 0.53 10.9 0.0 3.7 3 0 0 3 3 3 1 P63C domain rve_3 PF13683.6 PRP72887.1 - 0.0019 17.9 0.8 3.8 7.4 0.0 3.2 3 0 0 3 3 3 2 Integrase core domain gag_pre-integrs PF13976.6 PRP72887.1 - 0.0022 17.8 1.8 12 5.9 0.0 3.5 3 0 0 3 3 3 0 GAG-pre-integrase domain DUF2256 PF10013.9 PRP72887.1 - 0.032 14.4 9.4 13 6.1 0.3 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF261 PF03196.13 PRP72887.1 - 0.053 13.6 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF261 FOXP-CC PF16159.5 PRP72887.1 - 0.062 13.9 0.9 57 4.4 0.0 4.0 4 0 0 4 4 4 0 FOXP coiled-coil domain Mhr1 PF12829.7 PRP72887.1 - 0.15 12.2 3.0 26 5.0 0.0 3.4 3 0 0 3 3 3 0 Transcriptional regulation of mitochondrial recombination DUF3293 PF11697.8 PRP72887.1 - 0.18 12.3 0.0 18 5.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3293) DUF5311 PF17238.2 PRP72887.1 - 0.22 11.4 2.1 86 3.0 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5311) Transcript_VP30 PF11507.8 PRP72887.1 - 1.8 8.7 6.7 96 3.1 0.1 4.2 3 3 1 4 4 4 0 Ebola virus-specific transcription factor VP30 MBOAT_2 PF13813.6 PRP72887.1 - 3.9 7.8 18.5 0.88 9.9 0.2 4.6 6 0 0 6 6 5 0 Membrane bound O-acyl transferase family Actin PF00022.19 PRP72891.1 - 2.3e-67 227.4 0.0 2.6e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Actin DUF5082 PF16888.5 PRP72892.1 - 7.4e-05 23.0 0.7 0.56 10.5 0.1 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) DUF4455 PF14643.6 PRP72892.1 - 0.00086 18.1 6.3 0.15 10.6 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4455) Baculo_PEP_C PF04513.12 PRP72892.1 - 0.011 15.8 8.0 0.61 10.1 0.2 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FadA PF09403.10 PRP72892.1 - 0.017 15.6 21.1 0.93 10.0 0.1 5.2 3 2 2 5 5 5 0 Adhesion protein FadA DUF4359 PF14271.6 PRP72892.1 - 0.023 15.5 6.1 2.3 9.1 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) OmpH PF03938.14 PRP72892.1 - 0.1 12.9 17.1 1.1 9.6 2.3 3.4 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) Tweety PF04906.13 PRP72892.1 - 0.12 11.1 3.6 0.87 8.2 0.1 2.4 3 0 0 3 3 3 0 Tweety DUF148 PF02520.17 PRP72892.1 - 0.12 12.5 4.1 6.4 6.9 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF148 DP PF08781.10 PRP72892.1 - 0.15 12.0 4.0 4.8 7.1 0.4 2.5 2 0 0 2 2 2 0 Transcription factor DP Caskin-tail PF16632.5 PRP72892.1 - 0.15 12.5 1.6 7.9 7.0 0.2 2.8 2 0 0 2 2 2 0 C-terminal region of Caskin CCDC-167 PF15188.6 PRP72892.1 - 0.16 12.3 2.6 14 6.2 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 CdvA PF18822.1 PRP72892.1 - 0.23 11.3 5.0 6.9 6.5 0.4 2.7 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Utp12 PF04003.12 PRP72892.1 - 0.47 10.8 3.3 21 5.5 0.3 2.5 2 0 0 2 2 2 0 Dip2/Utp12 Family LOH1CR12 PF10158.9 PRP72892.1 - 0.56 10.2 3.9 16 5.5 0.2 2.9 2 1 0 2 2 2 0 Tumour suppressor protein TACC_C PF05010.14 PRP72892.1 - 1.9 8.2 9.6 6 6.6 2.1 3.1 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF725 PF05267.12 PRP72892.1 - 3.2 7.8 10.6 6 6.9 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF725) Snapin_Pallidin PF14712.6 PRP72892.1 - 3.2 8.2 11.1 2.3 8.7 0.4 3.4 4 0 0 4 4 4 0 Snapin/Pallidin Vps5 PF09325.10 PRP72892.1 - 4.7 6.7 7.9 12 5.4 0.9 2.3 2 0 0 2 2 2 0 Vps5 C terminal like GPS2_interact PF15784.5 PRP72893.1 - 0.001 19.5 2.7 0.024 15.0 0.4 3.6 3 0 0 3 3 3 1 G-protein pathway suppressor 2-interacting domain Retrotrans_gag PF03732.17 PRP72893.1 - 0.0098 16.1 0.2 0.033 14.5 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein Cytochrom_C PF00034.21 PRP72893.1 - 0.044 14.9 1.3 6 8.1 0.1 2.7 2 0 0 2 2 2 0 Cytochrome c DUF3384 PF11864.8 PRP72899.1 - 0.0084 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) DUF722 PF05263.11 PRP72899.1 - 0.045 14.0 1.6 0.79 9.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF722) RVT_1 PF00078.27 PRP72900.1 - 2.7e-44 151.3 1.9 8.4e-23 81.0 0.1 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PRP72900.1 - 1.4e-32 111.7 0.0 2.6e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PRP72900.1 - 8.5e-32 109.6 0.0 1.8e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Mob1_phocein PF03637.17 PRP72900.1 - 0.0029 17.6 1.3 2.7 8.0 0.1 2.6 2 0 0 2 2 2 2 Mob1/phocein family SHQ1 PF04925.15 PRP72900.1 - 0.013 15.1 1.8 3.7 7.1 0.2 2.4 2 0 0 2 2 2 0 SHQ1 protein DUF2635 PF10948.8 PRP72900.1 - 0.089 12.5 0.1 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) DUF2024 PF09630.10 PRP72900.1 - 0.47 10.3 5.0 34 4.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) EABR PF12180.8 PRP72900.1 - 1.7 8.3 4.7 2.4 7.8 0.2 2.8 3 0 0 3 3 3 0 TSG101 and ALIX binding domain of CEP55 Baculo_PEP_C PF04513.12 PRP72901.1 - 0.031 14.3 0.1 0.041 13.9 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4108 PF13390.6 PRP72904.1 - 6e-07 29.5 0.1 0.14 12.0 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4108) IBN_N PF03810.19 PRP72904.1 - 0.0021 17.9 2.6 5.8 6.9 0.1 4.0 3 1 0 3 3 3 1 Importin-beta N-terminal domain DNA_III_psi PF03603.13 PRP72904.1 - 0.0055 16.9 0.3 0.41 10.9 0.0 2.5 2 0 0 2 2 2 1 DNA polymerase III psi subunit Phenol_MetA_deg PF13557.6 PRP72904.1 - 0.01 15.8 1.0 7.4 6.4 0.0 2.9 3 0 0 3 3 3 0 Putative MetA-pathway of phenol degradation DUF4874 PF16173.5 PRP72904.1 - 0.036 13.7 4.9 4.6 6.9 0.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4874) DUF123 PF01986.16 PRP72904.1 - 0.2 12.2 1.4 1.5 9.4 0.0 2.9 4 1 0 4 4 4 0 Domain of unknown function DUF123 DUF2573 PF10835.8 PRP72904.1 - 0.43 11.0 3.8 1e+02 3.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2573) DUF2198 PF09964.9 PRP72904.1 - 0.84 9.7 5.8 66 3.7 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) Peptidase_S74 PF13884.6 PRP72904.1 - 1.7 9.0 6.9 56 4.2 0.0 3.7 4 0 0 4 4 4 0 Chaperone of endosialidase zf-C2H2_4 PF13894.6 PRP72906.1 - 0.095 13.6 1.6 0.095 13.6 1.6 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger DNA_pol_B_2 PF03175.13 PRP72907.1 - 3.7e-08 32.7 2.3 4.7e-08 32.3 2.3 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral UPA PF17217.3 PRP72908.1 - 0.0038 17.1 0.1 1.5 8.8 0.0 2.6 2 0 0 2 2 2 2 UPA domain zf-C2H2_4 PF13894.6 PRP72908.1 - 0.12 13.2 1.7 0.81 10.7 1.7 2.5 1 0 0 1 1 1 0 C2H2-type zinc finger MCD_N PF17408.2 PRP72908.1 - 0.15 12.2 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain MFS_1 PF07690.16 PRP72909.1 - 2.3e-08 33.4 11.2 3.7e-08 32.7 11.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily CD20 PF04103.15 PRP72909.1 - 8.8 6.4 11.3 2.4 8.2 2.2 2.2 2 0 0 2 2 2 0 CD20-like family HNH_2 PF13391.6 PRP72911.1 - 3.4e-08 33.5 0.0 9.5e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease PS_Dcarbxylase PF02666.15 PRP72912.1 - 1.6e-10 40.9 0.1 2.3e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.22 PRP72912.1 - 0.059 13.6 0.0 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M23 Biotin_lipoyl_2 PF13533.6 PRP72912.1 - 0.18 11.6 2.0 2.6 7.9 0.3 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like UCH_N PF16674.5 PRP72915.1 - 0.13 12.2 0.3 12 5.9 0.0 2.5 3 0 0 3 3 3 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 VitD-bind_III PF09164.10 PRP72920.1 - 0.14 12.2 0.9 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Vitamin D binding protein, domain III DUF3243 PF11588.8 PRP72920.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) PAS_5 PF07310.13 PRP72926.1 - 0.084 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 PAS domain Thiolase_C PF02803.18 PRP72927.1 - 1.8e-41 140.6 0.2 2.7e-41 140.0 0.2 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 PRP72927.1 - 2.7e-22 79.4 0.6 5.2e-22 78.5 0.4 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Asp_protease_2 PF13650.6 PRP72931.1 - 1.2e-08 35.5 0.0 0.003 18.2 0.0 3.0 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 PRP72931.1 - 2.2e-07 31.4 0.0 0.023 15.2 0.0 2.7 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Peptidase_A2E PF12382.8 PRP72931.1 - 0.0011 19.0 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 2 Retrotransposon peptidase RVP_2 PF08284.11 PRP72931.1 - 0.023 14.5 0.0 6.3 6.6 0.0 3.0 3 0 0 3 3 3 0 Retroviral aspartyl protease RVP PF00077.20 PRP72931.1 - 0.045 14.1 0.0 20 5.6 0.0 2.7 2 0 0 2 2 2 0 Retroviral aspartyl protease PknG_rubred PF16919.5 PRP72931.1 - 1.1 9.4 9.9 9.8 6.3 2.8 2.9 2 1 0 2 2 2 0 Protein kinase G rubredoxin domain zf-TRAF PF02176.18 PRP72933.1 - 0.12 13.0 0.1 0.26 12.0 0.1 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger Thiolase_N PF00108.23 PRP72934.1 - 0.076 12.4 0.0 0.086 12.2 0.0 1.0 1 0 0 1 1 1 0 Thiolase, N-terminal domain Dimer_Tnp_hAT PF05699.14 PRP72936.1 - 0.0006 19.5 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ABC2_membrane PF01061.24 PRP72938.1 - 3.4e-48 163.9 23.2 3.4e-48 163.9 23.2 2.2 3 0 0 3 3 3 1 ABC-2 type transporter PDR_CDR PF06422.12 PRP72938.1 - 7.6e-39 131.5 3.5 2.2e-23 81.9 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 PRP72938.1 - 4.2e-18 66.2 0.5 2.8e-08 34.4 0.2 2.6 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 PRP72938.1 - 2.4e-11 43.8 0.0 0.00025 21.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 PRP72938.1 - 5e-10 39.3 0.8 0.00052 19.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PRP72938.1 - 1.1e-09 37.9 1.1 0.0017 18.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 PRP72938.1 - 1.7e-06 28.6 0.7 0.07 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PRP72938.1 - 2e-06 28.1 2.0 0.043 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PRP72938.1 - 2.2e-06 28.2 0.1 0.11 12.9 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PRP72938.1 - 3.7e-06 27.3 0.7 0.15 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 PRP72938.1 - 1e-05 25.7 1.9 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 PRP72938.1 - 2.2e-05 24.5 1.4 0.02 14.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase OCD_Mu_crystall PF02423.15 PRP72938.1 - 4.1e-05 22.7 0.1 0.085 11.8 0.0 2.2 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family AAA_21 PF13304.6 PRP72938.1 - 4.4e-05 23.5 1.2 0.3 10.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PRP72938.1 - 6.1e-05 23.6 3.8 0.33 11.4 0.1 3.2 3 0 0 3 3 3 2 AAA domain ABC2_membrane_3 PF12698.7 PRP72938.1 - 0.00016 20.9 23.8 0.00017 20.8 21.2 2.3 2 1 0 2 2 2 1 ABC-2 family transporter protein cobW PF02492.19 PRP72938.1 - 0.00019 21.0 2.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 PRP72938.1 - 0.00044 20.2 0.5 1.3 9.1 0.2 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 PRP72938.1 - 0.00051 19.8 1.2 0.45 10.3 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 PRP72938.1 - 0.00088 19.0 0.2 1.6 8.3 0.1 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 PRP72938.1 - 0.0013 18.5 4.6 0.46 10.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 PRP72938.1 - 0.0014 18.6 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain Roc PF08477.13 PRP72938.1 - 0.0018 18.5 0.4 1.7 8.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF4227 PF14004.6 PRP72938.1 - 0.0018 18.2 0.1 4.9 7.2 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) AAA_24 PF13479.6 PRP72938.1 - 0.002 17.9 0.9 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 PRP72938.1 - 0.0031 16.8 1.9 1.4 8.1 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 PRP72938.1 - 0.0033 17.2 0.2 3.2 7.4 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 PRP72938.1 - 0.0044 17.0 3.9 1.1 9.1 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_14 PF13173.6 PRP72938.1 - 0.0061 16.6 0.7 2 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP72938.1 - 0.0098 16.3 0.4 5.2 7.5 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Rad51 PF08423.11 PRP72938.1 - 0.021 14.1 0.5 5.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Rad51 PseudoU_synth_1 PF01416.20 PRP72938.1 - 0.024 15.1 0.0 14 6.2 0.0 2.5 2 0 0 2 2 2 0 tRNA pseudouridine synthase Arf PF00025.21 PRP72938.1 - 0.025 14.0 0.6 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family dNK PF01712.19 PRP72938.1 - 0.032 14.1 0.6 8.4 6.2 0.3 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase NB-ARC PF00931.22 PRP72938.1 - 0.034 13.3 0.4 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.14 PRP72938.1 - 0.038 13.9 2.1 6.5 6.7 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Gtr1_RagA PF04670.12 PRP72938.1 - 0.054 12.8 0.3 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA PF00004.29 PRP72938.1 - 0.059 13.8 1.5 8 6.9 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 PRP72938.1 - 0.07 13.0 0.0 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 PRP72938.1 - 0.073 13.1 1.0 16 5.5 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 PRP72938.1 - 0.075 12.3 1.2 4.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Septin AAA_17 PF13207.6 PRP72938.1 - 0.086 13.3 1.3 19 5.7 0.3 2.7 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 PRP72938.1 - 0.093 12.2 0.3 8.7 5.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ATPase PF06745.13 PRP72938.1 - 0.14 11.5 0.9 15 4.8 0.1 2.4 2 0 0 2 2 2 0 KaiC SMC_N PF02463.19 PRP72938.1 - 0.15 11.5 0.0 22 4.4 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 PRP72938.1 - 0.16 12.3 1.4 13 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 PRP72938.1 - 0.2 11.7 3.0 14 5.7 0.4 3.2 3 0 0 3 3 3 0 Dynamin family RuvB_N PF05496.12 PRP72938.1 - 0.24 11.1 0.5 27 4.5 0.2 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PDR_assoc PF08370.11 PRP72938.1 - 0.44 10.3 9.7 1.5 8.6 0.1 3.2 3 0 0 3 3 2 0 Plant PDR ABC transporter associated DUF5452 PF17533.2 PRP72938.1 - 0.95 9.5 5.0 12 5.9 0.1 2.7 3 0 0 3 3 2 0 Family of unknown function (DUF5452) SRP54 PF00448.22 PRP72938.1 - 1.5 8.4 8.2 5.2 6.6 0.5 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain HATPase_c PF02518.26 PRP72939.1 - 7.3e-09 36.1 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2201_N PF13203.6 PRP72939.1 - 0.043 13.4 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain lci PF12197.8 PRP72939.1 - 3.3 7.6 4.7 21 5.0 0.1 3.5 4 0 0 4 4 4 0 Bacillus cereus group antimicrobial protein HNH_2 PF13391.6 PRP72942.1 - 7.6e-06 26.0 0.1 7.6e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 HNH endonuclease RT_RNaseH PF17917.1 PRP72944.1 - 9.6e-44 148.0 1.1 3.8e-33 113.9 0.0 2.7 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP72944.1 - 7.9e-31 106.1 0.0 2.4e-30 104.5 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP72944.1 - 1e-25 90.5 0.0 2.2e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 PRP72944.1 - 5e-22 77.8 0.0 1.2e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP72944.1 - 2.5e-17 63.2 0.5 6.8e-14 52.1 0.0 3.6 3 0 0 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 PRP72944.1 - 2.6e-07 30.8 0.1 2.1e-06 27.8 0.0 2.5 3 0 0 3 3 3 1 H2C2 zinc finger Chromo PF00385.24 PRP72944.1 - 2.2e-05 24.3 0.1 6.5e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MBOAT_2 PF13813.6 PRP72944.1 - 0.00069 19.8 0.1 0.45 10.8 0.0 2.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family rve_3 PF13683.6 PRP72944.1 - 0.081 12.7 0.0 0.93 9.3 0.0 2.7 2 0 0 2 2 2 0 Integrase core domain Phi-29_GP16_7 PF06720.11 PRP72944.1 - 0.11 12.3 0.1 20 5.0 0.0 3.0 2 2 1 3 3 3 0 Bacteriophage phi-29 early protein GP16.7 4PPT_N PF17837.1 PRP72945.1 - 0.074 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain HEAT_2 PF13646.6 PRP72948.1 - 0.00032 21.0 0.3 0.0012 19.2 0.1 2.0 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 PRP72948.1 - 0.0027 17.8 0.4 0.18 12.2 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat p450 PF00067.22 PRP72949.1 - 1.5e-14 53.6 0.0 1.8e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dynein_C PF18199.1 PRP72953.1 - 7.1e-49 166.7 0.0 1e-48 166.2 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain TGT PF01702.18 PRP72954.1 - 0.24 10.5 2.0 0.29 10.3 2.0 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Rad51 PF08423.11 PRP72959.1 - 1.5e-06 27.7 0.0 1.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 Barttin PF15462.6 PRP72961.1 - 0.11 12.3 0.8 0.13 12.0 0.8 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Hepatitis_core PF00906.20 PRP72961.1 - 0.27 10.7 6.0 0.33 10.5 6.0 1.1 1 0 0 1 1 1 0 Hepatitis core antigen Chromo PF00385.24 PRP72962.1 - 1.9e-13 50.1 0.0 2.5e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP72962.1 - 0.026 14.7 0.4 0.042 14.0 0.4 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 RhoGEF PF00621.20 PRP72965.1 - 3.7e-08 33.8 2.9 8.5e-08 32.6 0.0 2.4 2 1 0 2 2 2 1 RhoGEF domain DUF4093 PF13331.6 PRP72965.1 - 0.052 14.0 0.2 0.18 12.2 0.1 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4093) PAS_3 PF08447.12 PRP72966.1 - 1.4e-09 38.1 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 PRP72966.1 - 6.4e-06 26.4 0.0 5.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 PRP72966.1 - 0.0034 17.4 0.0 0.066 13.3 0.0 2.3 2 0 0 2 2 2 1 PAS domain Brix PF04427.18 PRP72966.1 - 0.0082 16.3 0.2 0.12 12.4 0.0 2.2 1 1 1 2 2 2 1 Brix domain PAS PF00989.25 PRP72966.1 - 0.0084 16.1 0.0 0.027 14.5 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 PRP72966.1 - 0.0092 16.2 0.0 0.042 14.1 0.0 2.0 2 0 0 2 2 2 1 PAS fold Seadorna_VP6 PF07407.11 PRP72966.1 - 0.15 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein Chordopox_A33R PF05966.12 PRP72969.1 - 0.076 12.3 0.3 21 4.3 0.0 3.1 3 0 0 3 3 3 0 Chordopoxvirus A33R protein HELP PF03451.14 PRP72969.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 HELP motif DUF3430 PF11912.8 PRP72971.1 - 0.0049 17.0 4.8 0.0064 16.6 4.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Integrase_H2C2 PF17921.1 PRP72973.1 - 1.2e-19 70.1 1.4 1.2e-19 70.1 1.4 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PRP72973.1 - 0.00085 19.5 0.4 0.0018 18.5 0.4 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 PRP72973.1 - 0.0014 18.8 0.0 0.16 12.1 0.0 2.6 1 1 1 2 2 2 1 Integrase core domain MBOAT_2 PF13813.6 PRP72973.1 - 0.069 13.4 0.1 0.24 11.7 0.1 1.9 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family DUF4459 PF14673.6 PRP72973.1 - 0.17 11.8 0.4 0.38 10.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4459) Chromo PF00385.24 PRP72974.1 - 1.3e-12 47.4 0.1 1.7e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP72974.1 - 0.028 14.6 1.1 0.03 14.5 0.2 1.5 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 DUF4178 PF13785.6 PRP72974.1 - 0.045 13.9 0.2 0.047 13.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4178) GCS2 PF04107.13 PRP72975.1 - 0.032 13.6 0.0 0.034 13.5 0.0 1.0 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) NmrA PF05368.13 PRP72975.1 - 0.15 11.6 0.1 0.15 11.6 0.1 1.0 1 0 0 1 1 1 0 NmrA-like family BST2 PF16716.5 PRP72976.1 - 0.017 15.7 1.6 0.017 15.7 1.6 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 UvrD-helicase PF00580.21 PRP72976.1 - 0.017 14.6 5.1 0.02 14.4 5.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Exonuc_VII_L PF02601.15 PRP72976.1 - 1.6 8.2 6.8 2 7.9 6.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mit_KHE1 PF10173.9 PRP72976.1 - 4.4 7.3 8.2 7.3 6.6 8.2 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related BSP_II PF05432.11 PRP72978.1 - 0.017 14.9 15.3 0.019 14.7 15.3 1.0 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Prothymosin PF03247.14 PRP72978.1 - 0.3 11.6 23.7 0.36 11.3 23.7 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family Paf1 PF03985.13 PRP72978.1 - 0.71 8.8 10.8 0.82 8.6 10.8 1.0 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 PRP72978.1 - 2.4 8.1 5.6 2.6 8.0 5.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TRAP_alpha PF03896.16 PRP72978.1 - 2.6 7.2 5.1 2.9 7.0 5.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 PRP72978.1 - 7.2 5.8 12.4 8.2 5.7 12.4 1.0 1 0 0 1 1 1 0 NOA36 protein DARPP-32 PF05395.12 PRP72978.1 - 7.3 6.8 11.9 8.7 6.5 11.9 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF4746 PF15928.5 PRP72978.1 - 7.6 5.9 8.7 8.2 5.7 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Tub PF01167.18 PRP72979.1 - 0.07 12.9 0.3 1.2 8.8 0.3 2.0 1 1 0 1 1 1 0 Tub family DUF2140 PF09911.9 PRP72980.1 - 0.11 12.1 0.9 0.2 11.2 0.5 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF1289 PF06945.13 PRP72980.1 - 0.28 11.0 3.9 0.39 10.6 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) UPF0239 PF06783.11 PRP72980.1 - 0.4 10.9 6.0 0.69 10.1 6.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) CoA_trans PF01144.23 PRP72985.1 - 1.2e-76 256.9 0.1 1.4e-76 256.7 0.1 1.1 1 0 0 1 1 1 1 Coenzyme A transferase Mal_decarbox_Al PF16957.5 PRP72985.1 - 0.069 11.5 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Glutaredoxin2_C PF04399.13 PRP72986.1 - 0.39 10.6 5.8 0.28 11.0 2.7 2.3 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain DUF1700 PF08006.11 PRP72986.1 - 4.3 6.8 6.2 10 5.6 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) FA_hydroxylase PF04116.13 PRP72987.1 - 2.7e-24 86.0 13.9 2.7e-24 86.0 13.9 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DASH_Ask1 PF08655.10 PRP72987.1 - 0.027 14.3 0.6 0.071 13.0 0.3 1.8 2 0 0 2 2 2 0 DASH complex subunit Ask1 tRNA-synt_1d PF00750.19 PRP72988.1 - 9.8e-69 231.9 0.0 1.9e-68 231.0 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 PRP72988.1 - 9.9e-27 93.5 0.0 2.4e-26 92.2 0.0 1.7 2 0 0 2 2 2 1 DALR anticodon binding domain tRNA-synt_1 PF00133.22 PRP72988.1 - 2.5e-05 22.7 0.0 4.2e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 PRP72988.1 - 0.0091 15.4 0.4 0.046 13.1 0.0 1.8 1 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PRP72988.1 - 0.028 13.2 0.1 0.048 12.4 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) SID-1_RNA_chan PF13965.6 PRP72989.1 - 2.1e-90 303.9 18.7 2.1e-90 303.9 18.7 2.8 4 1 0 4 4 3 1 dsRNA-gated channel SID-1 zf-C3HC4_3 PF13920.6 PRP72989.1 - 2.2e-07 30.6 12.9 4.3e-07 29.7 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP72989.1 - 9e-05 22.2 14.3 0.00017 21.3 14.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HMMR_N PF15905.5 PRP72989.1 - 0.0001 21.9 27.8 0.0001 21.9 27.8 6.7 1 1 5 7 7 7 2 Hyaluronan mediated motility receptor N-terminal Prok-RING_4 PF14447.6 PRP72989.1 - 0.00054 19.8 12.8 0.00096 19.0 12.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PRP72989.1 - 0.0006 19.6 15.7 0.0012 18.7 15.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP72989.1 - 0.0033 17.7 14.0 0.0068 16.7 14.0 1.6 1 0 0 1 1 1 1 Ring finger domain BRE1 PF08647.11 PRP72989.1 - 0.0057 16.7 15.0 0.0057 16.7 15.0 8.5 4 2 4 9 9 8 2 BRE1 E3 ubiquitin ligase zf-RING_5 PF14634.6 PRP72989.1 - 0.018 15.0 14.9 0.039 13.9 14.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 PRP72989.1 - 0.26 11.3 9.9 0.6 10.2 9.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 PRP72989.1 - 7.8 6.4 10.9 20 5.1 10.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPP_enzyme_N PF02776.18 PRP72990.1 - 1.5e-35 122.4 0.0 2.5e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 PRP72990.1 - 5.8e-19 68.2 0.0 1.8e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 PRP72990.1 - 2.9e-17 62.9 0.0 8.7e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF488 PF04343.13 PRP72990.1 - 0.22 12.1 4.5 0.23 12.0 2.6 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF488 ArfGap PF01412.18 PRP72991.1 - 1.7e-41 141.0 0.0 3e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pkinase PF00069.25 PRP72991.1 - 1.1e-37 129.8 0.0 1.6e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP72991.1 - 8e-19 67.9 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ada3 PF10198.9 PRP72992.1 - 1.3e-17 64.2 11.8 1.3e-17 64.2 11.8 2.8 3 1 1 4 4 4 1 Histone acetyltransferases subunit 3 Macoilin PF09726.9 PRP72992.1 - 0.024 13.2 16.5 0.048 12.2 16.5 1.4 1 1 0 1 1 1 0 Macoilin family EDR1 PF14381.6 PRP72992.1 - 0.14 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Nucleoside_tran PF01733.18 PRP72993.1 - 2e-33 116.1 10.6 5.2e-17 62.2 2.6 2.2 1 1 1 2 2 2 2 Nucleoside transporter RseC_MucC PF04246.12 PRP72993.1 - 2.5 8.1 10.9 0.09 12.7 1.2 2.9 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Cullin PF00888.22 PRP72994.1 - 6.2e-21 74.7 2.4 6.2e-21 74.7 2.4 2.6 2 1 0 3 3 3 2 Cullin family ANAPC2 PF08672.11 PRP72994.1 - 8.6e-07 29.4 0.2 4.5e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 MPM1 PF17234.2 PRP72996.1 - 0.038 14.2 5.8 0.045 14.0 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 BST2 PF16716.5 PRP72996.1 - 0.13 12.9 12.1 0.073 13.7 2.4 2.9 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 GDE_C PF06202.14 PRP72996.1 - 0.22 10.4 1.7 0.25 10.2 1.7 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Phage_Mu_Gam PF07352.12 PRP72996.1 - 0.36 10.7 14.2 2.3 8.1 1.1 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF2651 PF10852.8 PRP72999.1 - 0.12 13.0 0.1 0.12 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2651) PHD_4 PF16866.5 PRP73005.1 - 0.016 15.3 4.8 2 8.6 0.5 2.7 2 0 0 2 2 2 0 PHD-finger DUF5637 PF18687.1 PRP73005.1 - 0.019 14.9 0.1 15 5.7 0.0 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5637) FANCI_S3 PF14677.6 PRP73005.1 - 0.059 13.1 3.2 3.1 7.5 0.2 2.1 1 1 1 2 2 2 0 FANCI solenoid 3 Calponin PF00402.18 PRP73005.1 - 0.11 12.1 3.0 8.4 6.1 0.2 2.3 2 0 0 2 2 2 0 Calponin family repeat RVT_1 PF00078.27 PRP73006.1 - 4e-20 72.3 0.1 6.6e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PRP73006.1 - 7.5e-16 58.0 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 PRP73006.1 - 1.9e-15 57.3 0.0 2.7e-06 28.0 0.0 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 PRP73006.1 - 7.9e-12 45.6 0.0 0.00016 22.2 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 PRP73006.1 - 2e-07 31.2 0.0 3.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease PF09668.10 PRP73006.1 - 9.7e-06 25.4 0.0 0.074 12.8 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.20 PRP73006.1 - 9e-05 22.7 0.0 0.59 10.5 0.0 2.9 2 0 0 2 2 2 2 Retroviral aspartyl protease BiPBP_C PF06832.12 PRP73006.1 - 0.00011 22.2 0.0 0.53 10.4 0.0 2.7 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family zf-CCHC_3 PF13917.6 PRP73006.1 - 0.0022 17.9 4.4 1 9.4 0.4 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 PRP73006.1 - 0.0036 17.3 10.5 0.39 10.9 1.7 2.6 2 0 0 2 2 2 2 Zinc knuckle Peptidase_A2B PF12384.8 PRP73006.1 - 0.0083 15.7 0.0 3.5 7.1 0.0 2.4 2 0 0 2 2 2 2 Ty3 transposon peptidase zf-C2H2_10 PF16588.5 PRP73006.1 - 0.026 14.2 8.7 1.1 9.0 1.2 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger RVP_2 PF08284.11 PRP73006.1 - 0.2 11.5 0.0 8.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease zf-CCHC_2 PF13696.6 PRP73006.1 - 6 6.8 9.9 16 5.4 1.6 2.7 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH_2 PF17919.1 PRP73007.1 - 5.9e-94 308.6 0.0 1.6e-31 108.3 0.0 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PRP73007.1 - 4.1e-93 306.7 0.0 2.4e-36 124.2 0.0 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP73007.1 - 2.8e-44 149.0 8.3 1.6e-21 76.2 1.1 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 PRP73007.1 - 2.1e-27 96.1 0.5 3.8e-27 95.2 0.5 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PRP73007.1 - 7.6e-23 81.0 1.5 2.2e-14 53.7 0.1 2.9 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 PRP73007.1 - 1.7e-15 56.9 1.4 2.3e-06 27.7 0.1 2.7 2 0 0 2 2 2 2 H2C2 zinc finger DUF4125 PF13526.6 PRP73007.1 - 0.00014 21.5 0.5 0.67 9.5 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4125) Ferrochelatase PF00762.19 PRP73007.1 - 0.0064 15.6 0.1 2.7 7.0 0.0 2.4 2 0 0 2 2 2 2 Ferrochelatase BCS1_N PF08740.11 PRP73007.1 - 0.011 15.8 6.0 1.7 8.6 0.1 3.1 2 1 0 2 2 2 0 BCS1 N terminal DUF2543 PF10820.8 PRP73007.1 - 0.011 15.9 0.9 4.2 7.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) gag_pre-integrs PF13976.6 PRP73007.1 - 0.081 12.8 0.1 21 5.1 0.0 2.6 2 0 0 2 2 2 0 GAG-pre-integrase domain DUF727 PF05303.12 PRP73007.1 - 0.29 11.2 3.7 54 3.9 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF727) DUF2256 PF10013.9 PRP73007.1 - 0.5 10.5 3.7 21 5.3 0.3 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) MBOAT_2 PF13813.6 PRP73007.1 - 1.8 8.9 8.4 1.6 9.1 0.2 3.5 4 0 0 4 4 4 0 Membrane bound O-acyl transferase family APOC4 PF15119.6 PRP73007.1 - 4.2 7.7 11.5 17 5.7 0.1 4.6 5 0 0 5 5 4 0 Apolipoprotein C4 PXA PF02194.15 PRP73008.1 - 0.15 12.0 0.8 21 5.0 0.1 2.4 2 0 0 2 2 2 0 PXA domain p450 PF00067.22 PRP73013.1 - 6.4e-54 183.4 0.0 7.2e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHASE9 PF17153.4 PRP73013.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular Myosin_TH1 PF06017.13 PRP73015.1 - 1.1e-38 132.8 2.1 1.3e-38 132.6 2.1 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 PRP73015.1 - 0.00018 21.0 2.6 0.00018 21.0 2.6 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF4743 PF15916.5 PRP73015.1 - 0.0055 16.7 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) VirE PF05272.11 PRP73017.1 - 7.1e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E AAA PF00004.29 PRP73017.1 - 0.0013 19.1 0.0 0.0035 17.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 PRP73017.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.14 PRP73017.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 PRP73017.1 - 0.019 15.4 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 PRP73017.1 - 0.041 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 PRP73017.1 - 0.06 13.7 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 PRP73017.1 - 0.068 13.2 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 PRP73017.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 PRP73017.1 - 0.12 12.9 0.0 1.2 9.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter START PF01852.19 PRP73020.1 - 0.065 12.6 0.1 0.079 12.3 0.1 1.1 1 0 0 1 1 1 0 START domain DUF269 PF03270.13 PRP73020.1 - 0.081 13.0 0.1 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF269 RVT_1 PF00078.27 PRP73023.1 - 3e-38 131.6 0.3 3.3e-23 82.4 0.2 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 PRP73023.1 - 9.3e-34 115.9 0.0 1.7e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP73023.1 - 5e-33 113.1 0.0 3.8e-32 110.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP73023.1 - 2.8e-20 72.2 0.1 6.3e-20 71.0 0.1 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PRP73023.1 - 3.1e-05 24.1 0.0 6.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 PRP73023.1 - 0.5 10.6 1.6 4.9 7.4 0.1 2.8 3 0 0 3 3 3 0 Integrase core domain BCAS2 PF05700.11 PRP73024.1 - 9.8e-56 188.7 7.9 1.1e-55 188.5 7.9 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) ComGF PF15980.5 PRP73024.1 - 0.0082 16.5 1.9 0.016 15.6 1.9 1.4 1 0 0 1 1 1 1 Putative Competence protein ComGF CCDC85 PF10226.9 PRP73024.1 - 0.01 15.5 4.4 0.026 14.2 3.9 1.8 1 1 1 2 2 2 0 CCDC85 family ERM PF00769.19 PRP73024.1 - 0.012 15.4 8.0 0.016 15.1 8.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Thioredoxin_12 PF18400.1 PRP73024.1 - 0.036 13.9 0.1 0.052 13.4 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain AKAP7_NLS PF10469.9 PRP73024.1 - 0.043 13.7 0.2 0.066 13.1 0.2 1.3 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain SKA2 PF16740.5 PRP73024.1 - 0.17 11.7 6.4 0.71 9.7 6.4 2.0 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 XkdW PF09636.10 PRP73024.1 - 0.19 11.8 5.2 0.25 11.5 1.1 2.3 2 0 0 2 2 2 0 XkdW protein MYO10_CC PF16735.5 PRP73024.1 - 0.22 11.7 7.5 0.44 10.7 0.2 2.9 2 1 0 2 2 2 0 Unconventional myosin-X coiled coil domain DUF3450 PF11932.8 PRP73024.1 - 3.3 6.9 9.0 3.5 6.9 6.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Peroxin-13_N PF04088.13 PRP73028.1 - 0.099 12.9 0.1 0.22 11.8 0.0 1.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region PPR PF01535.20 PRP73029.1 - 0.0074 16.5 0.1 7.8 7.0 0.0 3.2 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 PRP73029.1 - 0.076 13.2 0.1 3 8.1 0.0 2.8 1 1 1 2 2 2 0 PPR repeat family MHB PF16525.5 PRP73031.1 - 0.01 16.1 1.3 0.36 11.1 0.6 2.4 2 1 1 3 3 3 0 Haemophore, haem-binding Phasin_2 PF09361.10 PRP73031.1 - 0.033 14.5 0.0 0.3 11.4 0.2 1.9 2 0 0 2 2 2 0 Phasin protein ABC_transp_aux PF09822.9 PRP73032.1 - 0.017 14.6 0.4 0.021 14.3 0.4 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system THP2 PF09432.10 PRP73032.1 - 0.018 15.1 1.8 0.03 14.4 1.1 1.6 1 1 1 2 2 2 0 Tho complex subunit THP2 Strep_SA_rep PF06696.11 PRP73032.1 - 0.042 13.8 0.9 0.1 12.6 0.9 1.7 1 1 0 1 1 1 0 Streptococcal surface antigen repeat DUF4304 PF14137.6 PRP73032.1 - 0.11 12.6 1.2 0.14 12.3 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) DUF5344 PF17279.2 PRP73036.1 - 0.00034 21.1 0.0 1.5 9.4 0.0 2.8 2 0 0 2 2 2 2 Family of unknown function (DUF5344) IL4 PF00727.18 PRP73036.1 - 0.1 12.9 0.0 30 4.9 0.0 2.9 3 0 0 3 3 3 0 Interleukin 4 SF-assemblin PF06705.11 PRP73036.1 - 0.15 11.4 0.3 19 4.5 0.0 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin Macoilin PF09726.9 PRP73036.1 - 7 5.1 13.4 11 4.5 13.4 1.2 1 0 0 1 1 1 0 Macoilin family GCP5-Mod21 PF14609.6 PRP73037.1 - 0.27 9.5 0.0 0.35 9.2 0.0 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Syja_N PF02383.18 PRP73038.1 - 4.4e-38 131.4 0.0 5.2e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 SacI homology domain Integrase_H2C2 PF17921.1 PRP73039.1 - 6.7e-16 58.1 0.3 1.4e-15 57.1 0.3 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP73039.1 - 2.3e-13 50.4 0.5 4.8e-13 49.3 0.1 1.8 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.10 PRP73039.1 - 1e-06 28.8 0.0 2.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Chromo PF00385.24 PRP73039.1 - 0.0011 18.8 0.5 0.0044 16.9 0.5 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4995 PF16386.5 PRP73039.1 - 0.13 12.3 0.8 38 4.4 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function Phage_Mu_Gam PF07352.12 PRP73039.1 - 2 8.3 4.6 3.2 7.6 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein rve PF00665.26 PRP73040.1 - 0.0036 17.5 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain SipA_VBS PF17985.1 PRP73042.1 - 0.077 12.9 0.4 0.13 12.2 0.4 1.4 1 0 0 1 1 1 0 SipA vinculin binding site RT_RNaseH_2 PF17919.1 PRP73043.1 - 9.4e-42 141.1 0.0 1.8e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PRP73043.1 - 2.4e-24 85.6 0.0 9.6e-11 41.9 0.0 2.5 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP73043.1 - 4.5e-20 72.1 0.4 6.4e-18 65.1 0.1 3.1 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 PRP73043.1 - 8.9e-15 55.1 0.0 7.6e-06 26.5 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 PRP73043.1 - 1e-11 45.2 0.0 0.00023 21.7 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 PRP73043.1 - 2.2e-06 27.5 0.0 0.1 12.4 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease RVP PF00077.20 PRP73043.1 - 7.3e-06 26.2 0.0 0.28 11.5 0.0 2.9 2 0 0 2 2 2 2 Retroviral aspartyl protease Peptidase_A17 PF05380.13 PRP73043.1 - 1.1e-05 25.5 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 2 Pao retrotransposon peptidase BiPBP_C PF06832.12 PRP73043.1 - 0.00012 22.1 0.0 0.81 9.8 0.0 2.7 2 0 0 2 2 2 2 Penicillin-Binding Protein C-terminus Family Peptidase_A2B PF12384.8 PRP73043.1 - 0.00028 20.5 0.0 0.97 9.0 0.0 2.4 2 0 0 2 2 2 2 Ty3 transposon peptidase rve PF00665.26 PRP73043.1 - 0.0028 17.9 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 1 1 Integrase core domain zf-CCHC_3 PF13917.6 PRP73043.1 - 0.004 17.1 4.4 1.5 8.8 0.4 2.8 2 0 0 2 2 2 2 Zinc knuckle DUF3618 PF12277.8 PRP73043.1 - 0.0056 16.9 0.0 6.7 7.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3618) RVP_2 PF08284.11 PRP73043.1 - 0.0058 16.4 0.0 5.6 6.7 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease zf-CCHC PF00098.23 PRP73043.1 - 0.007 16.4 10.5 0.56 10.4 1.7 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 PRP73043.1 - 0.052 13.3 8.7 1.6 8.5 1.2 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger PHP_C PF13263.6 PRP73043.1 - 0.091 12.5 0.3 23 4.9 0.0 2.7 2 0 0 2 2 2 0 PHP-associated DUF1758 PF05585.12 PRP73043.1 - 0.16 11.7 0.0 27 4.5 0.0 2.3 2 0 0 2 2 2 0 Putative peptidase (DUF1758) gag-asp_proteas PF13975.6 PRP73044.1 - 0.00024 21.6 0.0 0.00069 20.1 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PRP73044.1 - 0.00076 20.1 0.0 0.0045 17.6 0.0 2.3 1 1 1 2 2 2 1 Aspartyl protease CelD_N PF02927.14 PRP73047.1 - 0.079 13.9 0.0 0.15 12.9 0.0 1.4 1 0 0 1 1 1 0 Cellulase N-terminal ig-like domain Retrotrans_gag PF03732.17 PRP73048.1 - 0.00017 21.8 0.5 0.00031 20.9 0.5 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF2972 PF11186.8 PRP73048.1 - 0.044 13.7 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) FtsX_ECD PF18075.1 PRP73048.1 - 0.11 13.2 0.2 0.29 11.8 0.2 1.7 1 0 0 1 1 1 0 FtsX extracellular domain Rap_GAP PF02145.15 PRP73051.1 - 6.2e-63 211.7 0.1 2.7e-62 209.6 0.0 1.9 2 0 0 2 2 2 1 Rap/ran-GAP Pkinase PF00069.25 PRP73055.1 - 1e-21 77.5 0.5 2e-21 76.6 0.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73055.1 - 4.7e-09 35.9 0.0 6.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 PRP73055.1 - 0.054 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4973 PF16343.5 PRP73055.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) C1_2 PF03107.16 PRP73055.1 - 0.38 11.1 3.7 0.85 10.0 3.7 1.6 1 0 0 1 1 1 0 C1 domain Kdo PF06293.14 PRP73055.1 - 3.2 7.1 6.8 5 6.4 1.5 2.7 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RsbRD_N PF14361.6 PRP73056.1 - 0.021 15.5 0.0 3.2 8.5 0.0 2.6 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain SAP PF02037.27 PRP73057.1 - 0.056 13.2 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 SAP domain Inhibitor_I78 PF11720.8 PRP73058.1 - 6.6e-07 29.3 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I78 family PKD PF00801.20 PRP73060.1 - 0.057 13.3 0.1 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 PKD domain zf-C2H2_jaz PF12171.8 PRP73061.1 - 3.8 7.9 7.2 12 6.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CRF-BP PF05428.11 PRP73062.1 - 0.076 11.8 0.0 9 5.0 0.0 2.1 2 0 0 2 2 2 0 Corticotropin-releasing factor binding protein (CRF-BP) LRRNT_2 PF08263.12 PRP73064.1 - 0.00011 22.4 0.8 0.00022 21.4 0.8 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 PRP73065.1 - 4.9e-09 35.8 13.7 5.3e-06 26.1 3.0 5.4 2 1 5 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 PRP73065.1 - 0.001 19.4 33.0 0.04 14.3 2.1 5.8 2 1 5 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP73065.1 - 0.0043 17.4 25.8 5.4 8.0 0.0 8.2 7 2 1 8 8 8 2 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP73065.1 - 2.7 8.4 13.5 0.097 13.0 3.1 3.4 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain UspA1_rep PF18792.1 PRP73066.1 - 0.087 13.3 0.6 27 5.6 0.1 2.6 2 0 0 2 2 2 0 Ubiquitous surface protein adhesin repeat MDM1 PF15501.6 PRP73066.1 - 0.73 8.9 24.6 0.17 11.0 6.8 2.0 1 1 1 2 2 2 0 Nuclear protein MDM1 SOG2 PF10428.9 PRP73066.1 - 8.5 5.4 17.0 11 5.1 17.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mtp PF03821.16 PRP73069.1 - 0.031 13.9 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter GP3_package PF16677.5 PRP73070.1 - 0.036 14.2 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 DNA-packaging protein gp3 SH2 PF00017.24 PRP73071.1 - 2.5e-15 56.3 1.0 6.4e-15 55.0 1.0 1.7 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 PRP73071.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 PRP73071.1 - 0.028 14.3 0.2 0.057 13.3 0.2 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain GAS PF13851.6 PRP73072.1 - 0.017 14.4 15.4 0.026 13.9 15.4 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding MRP-S26 PF14943.6 PRP73072.1 - 0.14 12.1 10.1 0.15 11.9 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4304 PF14137.6 PRP73072.1 - 0.18 12.0 3.1 0.23 11.6 2.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4304) eIF-4B PF06273.11 PRP73072.1 - 2 7.4 5.2 2.3 7.2 5.2 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Dynamin_M PF01031.20 PRP73073.1 - 0.019 14.2 0.2 0.023 13.9 0.2 1.1 1 0 0 1 1 1 0 Dynamin central region Linker_histone PF00538.19 PRP73073.1 - 0.11 12.9 0.8 2.3 8.7 0.1 2.6 2 1 1 3 3 3 0 linker histone H1 and H5 family RRP14 PF15459.6 PRP73074.1 - 0.009 16.6 1.1 3.5 8.3 0.1 2.6 2 0 0 2 2 2 2 60S ribosome biogenesis protein Rrp14 DUF2161 PF09929.9 PRP73074.1 - 0.019 15.1 0.2 4 7.6 0.0 2.7 1 1 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) GlutR_dimer PF00745.20 PRP73074.1 - 0.022 15.2 0.5 22 5.6 0.1 3.3 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain TMEM72 PF16054.5 PRP73074.1 - 0.048 13.4 0.2 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein family 72 Sec5 PF15469.6 PRP73074.1 - 0.049 13.4 1.7 6.1 6.6 0.2 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 VitD-bind_III PF09164.10 PRP73074.1 - 0.05 13.6 10.6 4.7 7.3 0.1 4.8 5 0 0 5 5 5 0 Vitamin D binding protein, domain III Spc110_C PF18520.1 PRP73074.1 - 0.65 9.7 6.6 23 4.7 0.2 3.5 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain DUF5533 PF17685.1 PRP73074.1 - 1.2 9.6 4.9 1.4e+02 2.8 0.0 4.3 3 1 0 4 4 4 0 Family of unknown function (DUF5533) rve PF00665.26 PRP73075.1 - 7e-14 52.1 0.0 9.4e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain SapB_2 PF03489.17 PRP73076.1 - 4.2e-05 23.6 0.1 7.5e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Saposin-like type B, region 2 BB_PF PF18063.1 PRP73076.1 - 0.0095 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Beta barrel Pore-forming domain DNA_pol_B_2 PF03175.13 PRP73077.1 - 0.002 17.1 0.1 0.0031 16.5 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral AKAP95 PF04988.12 PRP73077.1 - 0.03 14.6 0.5 0.59 10.3 0.0 2.9 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) HSP70 PF00012.20 PRP73078.1 - 6.5e-19 67.6 0.2 6.5e-19 67.5 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein BppU_N PF10651.9 PRP73078.1 - 0.074 12.7 0.1 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 BppU N-terminal domain Nop52 PF05997.12 PRP73079.1 - 3.3e-50 170.9 1.2 3.3e-50 170.9 1.2 1.7 2 0 0 2 2 2 1 Nucleolar protein,Nop52 Nop14 PF04147.12 PRP73079.1 - 0.0081 14.4 27.1 0.012 13.9 27.1 1.2 1 0 0 1 1 1 1 Nop14-like family CAF1 PF04857.20 PRP73079.1 - 0.015 14.5 4.5 0.017 14.3 3.6 1.4 1 1 0 1 1 1 0 CAF1 family ribonuclease BUD22 PF09073.10 PRP73079.1 - 0.025 13.9 25.3 0.036 13.4 25.3 1.2 1 0 0 1 1 1 0 BUD22 V_ATPase_I PF01496.19 PRP73079.1 - 0.03 12.3 1.0 0.042 11.8 1.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SDA1 PF05285.12 PRP73079.1 - 0.19 11.1 26.2 0.28 10.6 26.2 1.3 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 PRP73079.1 - 0.27 10.4 6.4 0.42 9.8 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 PRP73079.1 - 0.48 9.1 9.7 0.69 8.6 9.7 1.2 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 PRP73079.1 - 1.1 7.8 31.7 2.3 6.7 31.6 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP_sp32 PF07222.12 PRP73079.1 - 1.7 8.0 8.1 3.4 7.0 8.1 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Cwf_Cwc_15 PF04889.12 PRP73079.1 - 1.7 8.3 29.3 3.4 7.3 29.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 PRP73079.1 - 1.8 6.7 24.9 0.49 8.6 21.2 1.7 2 0 0 2 2 2 0 CDC45-like protein FRQ PF09421.10 PRP73079.1 - 4.3 5.2 18.5 5.8 4.8 18.5 1.1 1 0 0 1 1 1 0 Frequency clock protein zf-C3HC4_3 PF13920.6 PRP73080.1 - 0.00044 20.1 6.4 0.00044 20.1 6.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP73080.1 - 0.014 15.3 3.6 0.046 13.7 3.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 PRP73080.1 - 0.041 13.8 5.0 0.15 12.0 5.0 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.14 PRP73080.1 - 0.09 12.5 1.5 0.29 10.8 0.7 2.2 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 PRP73080.1 - 0.9 9.4 5.1 0.29 11.0 1.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain rve PF00665.26 PRP73081.1 - 1.4e-17 64.0 0.0 1.4e-11 44.6 0.0 3.4 2 1 1 3 3 3 2 Integrase core domain TnpW PF14202.6 PRP73081.1 - 0.0085 15.9 2.0 2.4 8.1 0.1 2.9 2 1 1 3 3 3 2 Transposon-encoded protein TnpW Lipin_N PF04571.14 PRP73081.1 - 0.062 13.3 0.3 14 5.7 0.1 2.3 2 0 0 2 2 2 0 lipin, N-terminal conserved region DUF4829 PF16111.5 PRP73081.1 - 3.1 8.6 6.8 9.5 7.0 0.9 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4829) rve PF00665.26 PRP73083.1 - 6.9e-19 68.2 0.0 8.3e-12 45.4 0.0 3.4 2 1 1 3 3 3 3 Integrase core domain DUF2540 PF10802.8 PRP73083.1 - 0.0053 16.8 1.3 3 8.0 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF2540) SF3A2 PF16835.5 PRP73083.1 - 0.015 15.6 0.1 0.62 10.5 0.0 2.4 1 1 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) Lipin_N PF04571.14 PRP73083.1 - 0.06 13.3 0.1 3.2 7.8 0.1 2.3 2 0 0 2 2 2 0 lipin, N-terminal conserved region Lipase_GDSL_3 PF14606.6 PRP73083.1 - 0.16 12.0 1.3 0.61 10.2 0.2 2.0 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF4611 PF15387.6 PRP73085.1 - 0.22 11.7 4.1 2.7 8.3 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pkinase_Tyr PF07714.17 PRP73087.1 - 4e-43 147.6 1.6 5.6e-21 75.0 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 PRP73087.1 - 2.8e-40 135.9 80.2 4.5e-09 35.9 5.5 10.9 7 4 3 10 10 10 9 Leucine rich repeat Pkinase PF00069.25 PRP73087.1 - 8.8e-36 123.6 0.4 8.4e-18 64.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain LRR_4 PF12799.7 PRP73087.1 - 4.1e-23 81.1 95.3 0.0002 21.7 4.8 12.7 5 3 11 16 16 16 13 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP73087.1 - 1.1e-16 61.0 3.7 3.9e-07 30.5 0.3 3.0 2 0 0 2 2 2 2 GPCR proteolysis site, GPS, motif BetR PF08667.10 PRP73087.1 - 0.05 13.6 0.1 4.5 7.3 0.0 3.5 4 0 0 4 4 4 0 BetR domain RdRP PF05183.12 PRP73088.1 - 1.8e-74 251.4 0.2 6.8e-74 249.6 0.0 1.9 2 0 0 2 2 2 1 RNA dependent RNA polymerase Helicase_C PF00271.31 PRP73088.1 - 1.5e-13 51.1 0.3 6.4e-13 49.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP73088.1 - 6.5e-11 42.3 0.3 1.8e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PRP73088.1 - 0.0004 20.7 1.5 0.0024 18.2 0.1 3.0 3 1 0 3 3 3 1 AAA domain ResIII PF04851.15 PRP73088.1 - 0.0052 16.8 0.1 0.017 15.2 0.1 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 PRP73088.1 - 0.013 15.3 10.8 0.37 10.5 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 PRP73088.1 - 0.033 14.5 0.5 0.2 12.0 0.5 2.2 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 PRP73088.1 - 0.039 13.0 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Toxin_25 PF08095.11 PRP73088.1 - 6.2 6.9 8.3 0.6 10.1 2.7 2.3 2 0 0 2 2 2 0 Hefutoxin family Pkinase_Tyr PF07714.17 PRP73089.1 - 6.3e-19 68.3 0.6 2e-17 63.3 0.6 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP73089.1 - 6.4e-17 61.1 24.6 2.8e-07 30.2 5.1 4.0 3 1 0 4 4 4 3 Leucine rich repeat Pkinase PF00069.25 PRP73089.1 - 5.4e-15 55.5 1.1 2.8e-13 49.8 1.1 2.4 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP73089.1 - 2.8e-09 37.1 35.3 0.00019 21.7 0.8 6.0 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP73089.1 - 6.3e-08 33.0 0.5 1.4e-07 31.9 0.5 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif PMP1_2 PF08114.11 PRP73089.1 - 0.013 15.2 4.6 0.029 14.1 3.2 2.2 2 0 0 2 2 2 0 ATPase proteolipid family TMEM154 PF15102.6 PRP73089.1 - 0.015 15.2 1.1 0.051 13.5 0.6 2.0 2 0 0 2 2 2 0 TMEM154 protein family Pkinase_Tyr PF07714.17 PRP73091.1 - 1.6e-25 89.9 0.4 2.7e-25 89.1 0.4 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP73091.1 - 6.8e-22 78.1 0.3 1.4e-21 77.1 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP73091.1 - 1.1e-17 63.5 33.9 1.6e-05 24.6 11.7 6.9 4 2 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 PRP73091.1 - 9.7e-17 60.8 45.9 1.8e-05 25.0 5.7 8.4 5 1 2 8 8 8 7 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.23 PRP73091.1 - 3.6e-16 59.4 0.0 8.8e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GPS PF01825.21 PRP73091.1 - 3.9e-11 43.3 1.7 1.3e-10 41.6 1.7 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_6 PF13516.6 PRP73091.1 - 0.0059 16.6 14.9 2 8.7 0.6 6.9 6 0 0 6 6 6 1 Leucine Rich repeat TMEM154 PF15102.6 PRP73091.1 - 0.029 14.3 0.4 0.085 12.8 0.4 1.8 1 0 0 1 1 1 0 TMEM154 protein family PMP1_2 PF08114.11 PRP73091.1 - 0.069 12.9 5.7 0.035 13.8 2.7 2.1 2 0 0 2 2 2 0 ATPase proteolipid family LRR_1 PF00560.33 PRP73091.1 - 0.095 13.3 26.3 2.1 9.2 1.0 9.8 8 1 0 8 8 8 0 Leucine Rich Repeat Tmemb_161AB PF10268.9 PRP73092.1 - 1.1e-31 110.1 24.7 1.8e-28 99.4 24.7 2.9 1 1 0 1 1 1 1 Predicted transmembrane protein 161AB DUF1129 PF06570.11 PRP73092.1 - 0.56 9.7 11.7 0.7 9.3 0.2 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) TRAP-gamma PF07074.12 PRP73092.1 - 0.66 9.5 5.2 0.098 12.2 0.5 2.0 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Pkinase_Tyr PF07714.17 PRP73093.1 - 4.5e-75 252.3 0.0 8.4e-75 251.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP73093.1 - 4.9e-64 212.0 88.8 6.1e-08 32.3 0.0 14.2 12 1 1 13 13 13 13 Leucine rich repeat Pkinase PF00069.25 PRP73093.1 - 2.2e-48 164.9 0.0 4.4e-48 163.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP73093.1 - 2.7e-45 151.6 92.7 3.4e-05 24.1 0.2 19.8 10 5 8 20 20 20 18 Leucine Rich repeats (2 copies) RasGEF PF00617.19 PRP73093.1 - 1.2e-41 142.9 1.5 3.4e-41 141.4 1.5 1.9 1 0 0 1 1 1 1 RasGEF domain LRR_1 PF00560.33 PRP73093.1 - 2.9e-11 42.3 86.0 3.1 8.7 0.3 25.4 26 2 1 27 27 26 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP73093.1 - 2.2e-05 24.1 85.6 0.67 10.2 0.1 21.1 22 0 0 22 22 22 4 Leucine Rich repeat Pkinase_fungal PF17667.1 PRP73093.1 - 6.3e-05 21.9 0.0 0.00013 20.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP73093.1 - 0.00044 19.3 0.2 0.0019 17.2 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain LRR_9 PF14580.6 PRP73093.1 - 0.0011 18.5 18.7 1.4 8.4 1.1 6.1 5 1 1 6 6 6 3 Leucine-rich repeat RasGEF_N PF00618.20 PRP73093.1 - 0.0016 18.6 0.0 0.0071 16.6 0.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif Kdo PF06293.14 PRP73093.1 - 0.0096 15.3 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP73093.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PrmA PF06325.13 PRP73095.1 - 8.4e-08 31.9 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5_C PF17286.2 PRP73095.1 - 7.6e-06 25.9 0.6 1.3e-05 25.1 0.6 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 PRP73095.1 - 0.0019 18.9 0.0 0.0061 17.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP73095.1 - 0.0032 17.3 0.0 0.013 15.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP73095.1 - 0.0037 17.9 0.0 0.018 15.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PRP73095.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PRMT5 PF05185.16 PRP73095.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 PRP73095.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 HalOD1 PF18545.1 PRP73096.1 - 0.033 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Halobacterial output domain 1 TFIIF_beta_N PF17683.1 PRP73098.1 - 0.024 15.3 0.6 0.027 15.2 0.6 1.1 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus AIM3 PF17096.5 PRP73098.1 - 2.2 9.3 6.8 3.4 8.7 6.8 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 RVT_1 PF00078.27 PRP73102.1 - 3.5e-12 46.3 0.0 4.6e-11 42.6 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Galactosyl_T PF01762.21 PRP73103.1 - 0.056 13.3 0.5 2.2 8.0 0.1 2.3 1 1 1 2 2 2 0 Galactosyltransferase YwhD PF08741.10 PRP73106.1 - 0.059 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 YwhD family Tk-SP_N-pro PF18237.1 PRP73107.1 - 0.002 18.1 0.2 3.2 7.9 0.1 2.6 2 0 0 2 2 2 2 Tk-SP N-propeptide domain Ferrochelatase PF00762.19 PRP73107.1 - 0.003 16.7 0.3 0.33 10.0 0.1 2.1 2 0 0 2 2 2 1 Ferrochelatase RRM_Rrp7 PF17799.1 PRP73107.1 - 0.0041 16.9 4.2 0.83 9.4 0.4 2.5 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain IBR PF01485.21 PRP73107.1 - 0.0063 16.7 1.5 2.8 8.2 0.2 2.6 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain CpXC PF14353.6 PRP73107.1 - 0.0066 16.5 0.6 2.3 8.3 0.1 2.4 2 0 0 2 2 2 2 CpXC protein zf_UBZ PF18439.1 PRP73107.1 - 0.0069 16.0 3.9 3.2 7.4 0.1 3.4 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 PRP73107.1 - 0.0097 16.7 8.9 0.27 12.2 1.8 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 PRP73107.1 - 0.011 15.8 8.9 0.5 10.4 1.6 3.0 2 1 0 2 2 2 0 BED zinc finger zf-RRPl_C4 PF17026.5 PRP73107.1 - 0.013 15.6 11.8 0.31 11.2 1.4 3.0 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_10 PF10058.9 PRP73107.1 - 0.038 13.7 0.3 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C2HC_2 PF13913.6 PRP73107.1 - 0.05 13.5 1.1 15 5.6 0.0 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type DUF2757 PF10955.8 PRP73107.1 - 0.078 13.2 2.8 5.9 7.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) DUF3654 PF12376.8 PRP73107.1 - 0.13 12.4 5.1 7.6 6.7 0.2 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF3654) LacAB_rpiB PF02502.18 PRP73107.1 - 0.2 11.7 1.8 5.7 6.9 0.5 2.2 1 1 1 2 2 2 0 Ribose/Galactose Isomerase UPF1_Zn_bind PF09416.10 PRP73107.1 - 0.41 10.6 12.5 0.88 9.5 1.6 3.2 2 2 1 3 3 3 0 RNA helicase (UPF2 interacting domain) TcdB_N PF12918.7 PRP73107.1 - 0.42 10.9 3.8 11 6.4 0.4 2.8 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain zinc_ribbon_4 PF13717.6 PRP73107.1 - 0.68 9.9 5.1 21 5.1 0.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbon_6 PF10005.9 PRP73107.1 - 0.92 10.2 5.9 22 5.8 0.1 3.1 3 1 1 4 4 4 0 zinc-ribbon domain zf-C2H2 PF00096.26 PRP73107.1 - 4.8 7.8 12.3 29 5.4 0.6 3.4 2 1 0 2 2 2 0 Zinc finger, C2H2 type ExoD PF06055.12 PRP73108.1 - 0.023 14.1 0.8 0.032 13.6 0.8 1.3 1 1 0 1 1 1 0 Exopolysaccharide synthesis, ExoD RT_RNaseH PF17917.1 PRP73110.1 - 2.9e-34 117.5 0.1 5.6e-34 116.6 0.0 1.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP73110.1 - 3.5e-22 78.3 0.0 1.8e-21 76.1 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP73111.1 - 3.6e-26 92.0 0.9 4.9e-26 91.6 0.9 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 PRP73111.1 - 0.07 12.5 0.8 0.22 10.9 0.1 2.0 2 1 0 2 2 2 0 DNA polymerase (viral) C-terminal domain RecQ_Zn_bind PF16124.5 PRP73114.1 - 8.3e-11 42.5 4.2 2.8e-10 40.7 4.2 2.0 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 PRP73114.1 - 8.6e-06 25.5 0.1 0.00017 21.3 0.1 2.4 1 1 0 1 1 1 1 RQC domain HRDC PF00570.23 PRP73114.1 - 0.0037 17.2 0.0 0.036 14.1 0.0 2.3 2 0 0 2 2 2 1 HRDC domain DUF4246 PF14033.6 PRP73116.1 - 1e-71 242.5 0.0 1.2e-71 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arf PF00025.21 PRP73116.1 - 3.7e-14 52.5 0.2 4.7e-13 48.9 0.2 2.4 1 1 1 2 2 2 1 ADP-ribosylation factor family 2OG-FeII_Oxy_5 PF13759.6 PRP73116.1 - 0.019 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Nab2p_Zf1 PF18260.1 PRP73116.1 - 0.074 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Roc PF08477.13 PRP73116.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DHR-2 PF06920.13 PRP73117.1 - 3.7e-18 65.5 0.0 5.2e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Dock homology region 2 rve PF00665.26 PRP73120.1 - 7e-13 48.8 0.0 8.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain TFB6 PF17110.5 PRP73120.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Delta_lysin PF05372.11 PRP73120.1 - 0.12 11.7 2.7 3.7 6.9 0.0 2.6 3 0 0 3 3 3 0 Delta lysin family Papilloma_E5 PF03025.14 PRP73121.1 - 0.036 14.2 5.5 0.035 14.3 5.5 1.0 1 0 0 1 1 1 0 Papillomavirus E5 ATP-synt_8 PF00895.20 PRP73121.1 - 9.4 6.8 9.3 8.2 7.0 0.7 2.1 1 1 1 2 2 2 0 ATP synthase protein 8 DnaJ PF00226.31 PRP73122.1 - 4.4e-27 94.0 0.4 5.4e-27 93.7 0.4 1.1 1 0 0 1 1 1 1 DnaJ domain CBS PF00571.28 PRP73126.1 - 1.7e-30 105.2 6.0 1.1e-09 38.6 0.4 4.2 4 0 0 4 4 4 4 CBS domain G_glu_transpept PF01019.21 PRP73128.1 - 2.6e-154 514.8 0.0 4.5e-154 514.0 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Indigoidine_A PF04227.12 PRP73128.1 - 3.1e-123 410.8 5.9 4.6e-123 410.2 5.9 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 PRP73128.1 - 4.9e-31 108.2 0.0 1e-30 107.1 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 PRP73128.1 - 0.00017 21.1 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase EF-hand_1 PF00036.32 PRP73129.1 - 3e-25 85.9 7.7 1.2e-05 24.5 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PRP73129.1 - 4.9e-22 78.2 4.3 2e-10 41.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP73129.1 - 5.8e-18 64.5 4.7 0.00072 19.4 0.2 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PRP73129.1 - 4.9e-17 60.3 5.7 0.00014 21.5 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PRP73129.1 - 3e-15 54.9 3.0 0.0022 17.4 0.1 4.3 4 0 0 4 4 4 4 EF hand DUF5580 PF17743.1 PRP73129.1 - 3.8e-05 22.4 0.3 0.0038 15.8 0.0 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 PRP73129.1 - 5.8e-05 23.4 1.0 0.0034 17.7 0.1 2.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 PRP73129.1 - 0.00013 22.7 0.3 0.19 12.6 0.1 2.2 1 1 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 PRP73129.1 - 0.0007 19.4 2.8 0.68 9.8 0.1 3.2 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 PRP73129.1 - 0.004 17.1 2.9 27 4.8 0.0 4.0 1 1 3 4 4 4 0 Cytoskeletal-regulatory complex EF hand Herpes_UL6 PF01763.16 PRP73129.1 - 0.049 12.1 0.0 0.074 11.6 0.0 1.4 2 0 0 2 2 2 0 Herpesvirus UL6 like Zn_clus PF00172.18 PRP73131.1 - 0.065 13.4 8.7 0.19 11.9 8.7 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3823 PF12866.7 PRP73132.1 - 0.13 12.5 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain COMM_domain PF07258.14 PRP73133.1 - 5.9e-20 71.2 0.0 9.8e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 COMM domain GBP PF02263.19 PRP73133.1 - 0.00063 19.1 0.1 0.00074 18.9 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Pro-kuma_activ PF09286.11 PRP73135.1 - 5.3e-31 107.8 0.5 1e-30 106.9 0.5 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain SNF2_N PF00176.23 PRP73136.1 - 1.5e-65 221.2 0.5 2.9e-65 220.3 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP73136.1 - 1.1e-19 70.8 0.0 3.8e-19 69.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 PRP73136.1 - 1.4e-15 57.3 5.7 1.4e-15 57.3 5.7 4.9 4 2 1 5 5 5 1 HSA ResIII PF04851.15 PRP73136.1 - 4.4e-09 36.6 1.1 3.6e-08 33.6 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 PRP73136.1 - 0.00019 21.5 1.1 0.00048 20.3 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD PF00270.29 PRP73136.1 - 0.00023 21.0 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-bind_6 PF13921.6 PRP73136.1 - 0.0024 18.1 2.7 0.0036 17.5 0.2 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Coat_X PF07552.11 PRP73136.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Spore Coat Protein X and V domain GST_N PF02798.20 PRP73139.1 - 1.4e-15 57.3 0.0 2.9e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP73139.1 - 8.8e-15 54.7 0.0 1.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP73139.1 - 4.5e-11 43.0 0.0 8.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP73139.1 - 2.2e-09 37.2 0.0 2.3e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP73139.1 - 4.1e-08 33.3 0.1 8.1e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PRP73139.1 - 4.4e-08 33.3 0.0 7.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 PRP73139.1 - 0.0097 15.7 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PRP73139.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2085 PF09858.9 PRP73139.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) FAD_binding_3 PF01494.19 PRP73140.1 - 1.1e-14 54.4 0.1 3.8e-14 52.7 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 PRP73140.1 - 7e-06 25.9 0.2 0.00014 21.6 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PRP73140.1 - 3.7e-05 23.0 0.1 8.9e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 PRP73140.1 - 5.2e-05 23.7 0.2 0.0026 18.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PRP73140.1 - 0.00015 21.1 0.2 0.0045 16.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP73140.1 - 0.00077 18.8 0.2 0.46 9.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP73140.1 - 0.00084 19.5 0.7 0.003 17.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PRP73140.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PRP73140.1 - 0.09 11.8 0.3 0.2 10.6 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Tropomyosin_1 PF12718.7 PRP73141.1 - 0.0015 18.7 10.5 0.0023 18.1 10.5 1.2 1 0 0 1 1 1 1 Tropomyosin like DUF1884 PF08967.10 PRP73141.1 - 0.038 14.2 0.0 0.089 13.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1884) Jnk-SapK_ap_N PF09744.9 PRP73141.1 - 0.21 11.8 8.5 0.32 11.2 8.5 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ANAPC4_WD40 PF12894.7 PRP73144.1 - 1.3e-06 28.6 3.4 1.2 9.4 0.0 6.2 7 0 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP73144.1 - 0.039 12.7 0.4 0.12 11.1 0.2 2.0 2 0 0 2 2 2 0 Nup133 N terminal like PQQ_2 PF13360.6 PRP73144.1 - 0.1 12.1 1.0 15 5.0 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain PQQ_3 PF13570.6 PRP73144.1 - 2.3 8.8 4.8 12 6.6 0.1 4.2 4 1 0 4 4 4 0 PQQ-like domain DUF4833 PF16117.5 PRP73145.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4833) Pectate_lyase_3 PF12708.7 PRP73146.1 - 8.4e-96 319.9 10.4 2.6e-82 275.8 3.6 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 PRP73146.1 - 5e-07 29.3 0.3 0.041 13.6 0.2 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 PRP73146.1 - 0.00026 20.9 3.8 0.00087 19.2 3.8 1.9 1 0 0 1 1 1 1 Right handed beta helix region Cyclin PF08613.11 PRP73146.1 - 0.0019 18.6 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin Carb_bind PF10645.9 PRP73146.1 - 0.0039 17.4 13.2 0.0039 17.4 13.2 2.8 2 1 1 3 3 3 2 Carbohydrate binding Trypan_PARP PF05887.11 PRP73146.1 - 0.0043 17.0 9.0 0.0078 16.2 9.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) GPS PF01825.21 PRP73151.1 - 0.0054 17.2 2.7 0.0054 17.2 2.7 1.8 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif DnaJ_C PF01556.18 PRP73153.1 - 3.3e-34 118.1 0.2 4.7e-34 117.6 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PRP73153.1 - 3.5e-23 81.5 2.6 6.2e-23 80.7 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PRP73153.1 - 5.7e-15 55.4 18.3 5.7e-15 55.4 18.3 1.8 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 PRP73153.1 - 0.0001 22.2 11.3 0.048 13.6 2.0 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 PRP73153.1 - 0.00034 20.6 5.5 0.12 12.4 0.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 PRP73153.1 - 0.078 12.6 7.7 0.28 10.8 0.9 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 PRP73153.1 - 0.32 11.0 11.1 2 8.5 11.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 PRP73153.1 - 1.1 9.3 10.4 0.13 12.2 0.8 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Cytochrom_c3_2 PF14537.6 PRP73153.1 - 1.3 9.5 7.0 3.7 8.1 7.0 1.8 1 1 0 1 1 1 0 Cytochrome c3 zinc_ribbon_2 PF13240.6 PRP73153.1 - 2.8 7.8 13.1 1.8 8.4 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-RING_10 PF16685.5 PRP73153.1 - 2.9 8.1 7.9 0.28 11.4 0.8 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 Zn_Tnp_IS1595 PF12760.7 PRP73153.1 - 6.1 6.9 11.3 1.5 8.9 0.5 3.2 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 PRP73153.1 - 9.9 6.6 13.2 38 4.8 3.6 3.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar Beta_helix PF13229.6 PRP73154.1 - 1.6e-05 24.9 9.6 1.6e-05 24.9 4.3 2.3 1 1 1 2 2 2 2 Right handed beta helix region Lyase_1 PF00206.20 PRP73155.1 - 5.6e-118 393.9 0.0 8.5e-118 393.3 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 PRP73155.1 - 9.5e-25 86.8 0.0 2.8e-24 85.3 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Acyltransferase PF01553.21 PRP73155.1 - 1.9e-14 53.4 0.0 4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase EF-hand_1 PF00036.32 PRP73155.1 - 5.4e-09 35.0 0.2 0.0005 19.4 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PRP73155.1 - 1.3e-08 34.6 0.7 6.5e-05 22.7 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 PRP73155.1 - 7.9e-08 32.6 2.3 0.0062 17.0 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP73155.1 - 8e-08 31.4 0.4 0.013 14.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP73155.1 - 1.2e-07 31.0 0.4 0.0071 16.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain DUF1398 PF07166.11 PRP73155.1 - 0.044 13.8 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1398) SAD_SRA PF02182.17 PRP73156.1 - 7.1e-41 139.5 0.0 7.1e-41 139.5 0.0 2.5 2 1 1 3 3 3 1 SAD/SRA domain P53_TAD PF08563.11 PRP73157.1 - 0.12 11.9 3.1 0.22 11.0 3.1 1.4 1 0 0 1 1 1 0 P53 transactivation motif TIG PF01833.24 PRP73158.1 - 2.1e-127 415.5 348.3 3.5e-09 36.6 9.2 30.0 24 4 5 29 29 29 28 IPT/TIG domain Pkinase_Tyr PF07714.17 PRP73158.1 - 9.3e-126 418.4 0.0 1.5e-70 237.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP73158.1 - 1e-93 313.5 0.0 1.2e-47 162.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 PRP73158.1 - 3.4e-09 36.4 0.4 0.0028 17.1 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 PRP73158.1 - 4.6e-08 32.7 3.3 1.6e-05 24.6 1.9 3.4 2 1 1 3 3 3 2 Leucine rich repeat Kinase-like PF14531.6 PRP73158.1 - 1e-06 28.3 0.0 0.00034 20.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PRP73158.1 - 1.6e-05 23.9 0.0 0.012 14.4 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase LRR_4 PF12799.7 PRP73158.1 - 0.00014 22.1 1.2 0.19 12.2 1.7 3.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 PRP73158.1 - 0.00017 20.7 0.1 0.0084 15.1 0.0 2.3 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PRP73158.1 - 0.00025 21.1 0.6 0.011 15.7 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP73158.1 - 0.00038 20.1 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 RIO1 family PAN_4 PF14295.6 PRP73158.1 - 0.00085 19.2 2.4 0.0028 17.5 2.4 1.9 1 0 0 1 1 1 1 PAN domain DUF1218 PF06749.12 PRP73158.1 - 6.7 7.3 8.0 0.83 10.2 1.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Pkinase_Tyr PF07714.17 PRP73159.1 - 4.1e-63 213.1 0.3 1.3e-62 211.5 0.3 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Flavoprotein PF02441.19 PRP73159.1 - 9e-46 155.5 0.0 2.2e-45 154.3 0.0 1.6 1 0 0 1 1 1 1 Flavoprotein LRR_4 PF12799.7 PRP73159.1 - 1.4e-45 152.5 109.0 1.9e-05 24.9 5.0 21.1 15 4 6 22 22 22 17 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP73159.1 - 1.2e-44 149.9 114.9 2.9e-06 26.9 4.9 17.0 8 4 12 22 22 22 17 Leucine rich repeat Pkinase PF00069.25 PRP73159.1 - 3.6e-43 147.8 0.1 1.3e-42 146.0 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain CAP_C PF08603.11 PRP73159.1 - 1.2e-22 80.2 0.2 2.9e-22 79.0 0.2 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal LRR_6 PF13516.6 PRP73159.1 - 5.7e-06 26.0 70.4 1.1 9.4 0.1 18.8 20 0 0 20 20 20 6 Leucine Rich repeat Pkinase_fungal PF17667.1 PRP73159.1 - 0.00017 20.5 0.2 0.00034 19.5 0.2 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP73159.1 - 0.00057 19.3 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ubiquitin PF00240.23 PRP73159.1 - 0.00078 19.2 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family LRR_9 PF14580.6 PRP73159.1 - 0.0014 18.2 0.8 0.0014 18.2 0.8 4.5 6 0 0 6 6 6 1 Leucine-rich repeat LRR_1 PF00560.33 PRP73159.1 - 0.0063 16.9 112.3 5.7 7.9 0.1 28.8 29 5 1 30 30 29 1 Leucine Rich Repeat Haspin_kinase PF12330.8 PRP73159.1 - 0.015 14.3 0.1 0.04 12.9 0.1 1.7 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PRP73159.1 - 0.019 14.3 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRRNT_2 PF08263.12 PRP73159.1 - 0.31 11.4 1.6 1.1 9.7 1.6 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Nas2_N PF18265.1 PRP73160.1 - 6.7e-25 86.8 0.1 1.3e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 PRP73160.1 - 1.3e-07 32.0 0.1 2e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 PRP73160.1 - 1.7e-07 31.0 0.4 3.3e-07 30.1 0.4 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PRP73160.1 - 1.3e-06 28.7 0.6 3.7e-06 27.2 0.6 1.9 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 PRP73160.1 - 0.011 16.1 2.0 0.013 15.8 0.1 2.1 3 0 0 3 3 3 0 PDZ domain DnaJ PF00226.31 PRP73161.1 - 2.2e-25 88.6 2.6 3.6e-25 87.9 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 PRP73161.1 - 2.9e-10 40.0 0.0 9.5e-09 35.2 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin Calsequestrin PF01216.17 PRP73161.1 - 0.062 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Calsequestrin GATA PF00320.27 PRP73162.1 - 2.1e-10 40.0 6.3 2.1e-10 40.0 6.3 2.4 2 0 0 2 2 2 1 GATA zinc finger SH3BP5 PF05276.14 PRP73162.1 - 1.2 8.9 10.6 0.23 11.2 5.2 2.2 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) GrpE PF01025.19 PRP73162.1 - 1.7 8.3 7.7 2.6 7.7 5.1 2.2 2 0 0 2 2 2 0 GrpE Lar_restr_allev PF14354.6 PRP73162.1 - 2 8.9 13.0 34 4.9 0.0 3.8 3 2 0 3 3 3 0 Restriction alleviation protein Lar Laminin_II PF06009.12 PRP73162.1 - 2 8.4 7.3 0.62 10.1 3.1 2.1 2 0 0 2 2 2 0 Laminin Domain II DUF241 PF03087.14 PRP73162.1 - 2.9 7.7 8.9 0.31 10.8 3.0 2.3 3 0 0 3 3 3 0 Arabidopsis protein of unknown function PHD_3 PF13922.6 PRP73162.1 - 3.5 8.1 6.9 0.6 10.5 0.6 3.0 4 0 0 4 4 4 0 PHD domain of transcriptional enhancer, Asx PHD PF00628.29 PRP73162.1 - 4 7.4 31.1 0.1 12.5 18.0 3.5 1 1 1 2 2 2 0 PHD-finger Hist_deacetyl PF00850.19 PRP73163.1 - 3.7e-88 296.0 0.1 4.8e-88 295.6 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Lipase_GDSL_2 PF13472.6 PRP73163.1 - 0.065 13.6 0.0 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Rhodanese_C PF12368.8 PRP73163.1 - 0.087 13.2 0.2 0.21 12.0 0.2 1.7 1 0 0 1 1 1 0 Rhodanase C-terminal Pkinase PF00069.25 PRP73164.1 - 1.3e-54 185.3 0.0 1.6e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73164.1 - 3.9e-21 75.5 0.0 8.8e-21 74.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP73164.1 - 0.00048 19.5 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP73164.1 - 0.011 15.2 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP73164.1 - 0.14 11.8 0.0 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 PRP73164.1 - 0.19 11.6 0.1 0.49 10.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family EF-hand_1 PF00036.32 PRP73165.1 - 1.5e-23 80.5 8.1 5.3e-06 25.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PRP73165.1 - 2.8e-22 76.7 6.6 2.3e-06 27.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 PRP73165.1 - 5.7e-20 71.5 20.0 2.6e-08 34.2 2.8 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PRP73165.1 - 3e-16 58.1 9.1 1.4e-05 24.3 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PRP73165.1 - 7.9e-16 57.7 8.9 1.8e-07 30.9 2.1 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_14 PF17959.1 PRP73165.1 - 0.017 15.5 5.3 1.5 9.3 0.1 3.6 3 1 1 4 4 4 0 EF-hand domain SPARC_Ca_bdg PF10591.9 PRP73165.1 - 0.018 15.4 9.1 0.03 14.6 0.3 3.6 3 1 1 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region TP53IP5 PF15331.6 PRP73165.1 - 0.025 14.7 2.6 0.051 13.7 2.6 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CEP19 PF14933.6 PRP73165.1 - 0.1 12.9 3.1 1.6 9.0 0.7 2.4 2 0 0 2 2 2 0 CEP19-like protein p25-alpha PF05517.12 PRP73165.1 - 1.1 9.4 6.7 8.6 6.5 0.3 2.8 2 1 1 3 3 3 0 p25-alpha EF-hand_7 PF13499.6 PRP73166.1 - 2.9e-06 27.6 0.1 5.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP73166.1 - 1.8e-05 24.0 0.3 0.071 12.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP73166.1 - 0.0017 18.2 0.1 2 8.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PRP73166.1 - 0.0042 16.9 0.3 0.83 9.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP73166.1 - 0.16 11.5 0.0 0.67 9.6 0.0 2.0 1 0 0 1 1 1 0 EF hand Rotavirus_VP3 PF06929.11 PRP73166.1 - 0.23 9.7 0.1 0.31 9.2 0.1 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein AAA_28 PF13521.6 PRP73167.1 - 1.7e-22 80.4 0.0 3.3e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 PRP73167.1 - 0.029 13.5 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MTS PF05175.14 PRP73170.1 - 1.9e-13 50.3 0.1 6.4e-13 48.6 0.0 1.9 2 1 1 3 3 3 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PRP73170.1 - 2e-08 34.2 0.0 3.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP73170.1 - 1.7e-07 31.8 0.0 1.1e-06 29.2 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 PRP73170.1 - 2.7e-06 27.2 0.0 4.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.9 PRP73170.1 - 3.3e-05 23.7 0.0 6.6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 PRP73170.1 - 6.9e-05 23.5 0.0 0.00032 21.4 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP73170.1 - 0.00019 22.0 0.0 0.00083 20.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 PRP73170.1 - 0.00048 19.5 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.12 PRP73170.1 - 0.00052 19.4 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 PRP73170.1 - 0.00062 19.2 0.0 0.00096 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 PRP73170.1 - 0.0035 17.0 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6-adenineMlase PF10237.9 PRP73170.1 - 0.0036 17.1 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Ubie_methyltran PF01209.18 PRP73170.1 - 0.073 12.4 0.0 0.25 10.6 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 PRP73170.1 - 0.086 13.9 0.0 0.15 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 PRP73170.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Haem_oxygenas_2 PF14518.6 PRP73171.1 - 8.7e-33 113.6 1.5 3.7e-31 108.3 0.2 2.6 2 0 0 2 2 2 2 Iron-containing redox enzyme GATA PF00320.27 PRP73172.1 - 2.6e-08 33.3 6.4 2.6e-08 33.3 6.4 2.9 4 1 0 4 4 4 1 GATA zinc finger CxC5 PF18718.1 PRP73172.1 - 0.22 11.6 8.5 1.6 8.8 3.7 2.3 1 1 1 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases C1_2 PF03107.16 PRP73172.1 - 0.27 11.6 14.6 0.5 10.7 2.4 3.2 3 0 0 3 3 3 0 C1 domain zinc-ribbons_6 PF07191.12 PRP73172.1 - 1.9 8.5 13.0 1.2 9.2 7.1 2.3 1 1 1 2 2 2 0 zinc-ribbons 7TM_GPCR_Srw PF10324.9 PRP73174.1 - 0.0087 15.4 0.4 0.37 10.0 0.0 2.0 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF1218 PF06749.12 PRP73174.1 - 0.028 14.9 0.2 9.7 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Pkinase PF00069.25 PRP73175.1 - 2e-50 171.6 0.0 3.1e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73175.1 - 1.8e-24 86.4 0.0 3e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP73175.1 - 4e-08 32.9 0.0 8.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SoxE PF06525.11 PRP73175.1 - 0.058 12.9 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain CK_II_beta PF01214.18 PRP73176.1 - 2.2e-80 268.8 0.0 3.4e-80 268.2 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit WD40 PF00400.32 PRP73176.1 - 1.7e-28 98.3 11.4 1.5e-05 25.7 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP73176.1 - 6.4e-05 23.2 0.4 0.21 11.9 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP73176.1 - 0.13 10.9 0.8 0.39 9.4 0.8 1.7 1 1 0 1 1 1 0 Nup133 N terminal like Kinesin PF00225.23 PRP73177.1 - 2.1e-40 138.6 0.9 2.1e-40 138.6 0.9 6.0 2 2 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PRP73177.1 - 2.5e-23 82.7 0.0 2.5e-23 82.7 0.0 3.1 2 0 0 2 2 2 1 Microtubule binding GFO_IDH_MocA PF01408.22 PRP73178.1 - 1.1e-11 45.6 0.0 1.7e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PRP73178.1 - 0.05 13.6 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Acetyltransf_1 PF00583.25 PRP73179.1 - 6.4e-11 42.5 0.1 1e-10 41.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PRP73179.1 - 3.9e-10 39.6 0.1 6.3e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 PRP73179.1 - 2.1e-08 34.5 0.0 3.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP73179.1 - 2.3e-08 34.0 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP73179.1 - 0.0011 19.0 0.0 0.085 12.9 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 PRP73179.1 - 0.18 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family RGS PF00615.19 PRP73180.1 - 7.3e-19 68.2 0.3 7.3e-19 68.2 0.3 2.3 2 1 0 2 2 2 1 Regulator of G protein signaling domain DUF1759 PF03564.15 PRP73180.1 - 0.24 11.3 4.8 0.095 12.6 0.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) C2 PF00168.30 PRP73181.1 - 3.6e-05 24.0 0.0 7.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain FH2 PF02181.23 PRP73182.1 - 4.9e-79 266.1 2.9 4.9e-79 266.1 2.9 2.3 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 PRP73182.1 - 2.9e-26 92.2 0.2 2.9e-26 92.2 0.2 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PRP73182.1 - 3e-20 72.7 1.0 1.4e-19 70.5 0.0 2.4 2 0 0 2 2 2 1 Diaphanous FH3 Domain C2 PF00168.30 PRP73182.1 - 8.2e-14 51.7 0.0 1.8e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF2730 PF10805.8 PRP73182.1 - 0.0002 21.4 1.5 1.5 9.0 0.0 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2730) SlyX PF04102.12 PRP73182.1 - 0.0099 16.5 0.2 0.3 11.7 0.1 3.3 3 0 0 3 3 3 1 SlyX Spectrin PF00435.21 PRP73182.1 - 0.022 15.3 0.0 0.11 13.0 0.0 2.2 1 0 0 1 1 1 0 Spectrin repeat TMF_TATA_bd PF12325.8 PRP73182.1 - 0.027 14.7 0.5 3.8 7.8 0.3 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 PRP73182.1 - 0.15 12.4 3.9 25 5.3 0.0 3.8 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Metallophos_2 PF12850.7 PRP73183.1 - 0.012 15.8 2.5 0.21 11.8 2.5 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF1772 PF08592.11 PRP73184.1 - 3.3e-15 56.6 0.7 6.6e-15 55.6 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) RasGEF PF00617.19 PRP73185.1 - 5.5e-51 173.3 0.9 5.5e-51 173.3 0.9 2.8 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP73185.1 - 1.9e-20 73.1 0.1 1.9e-20 73.1 0.1 3.2 3 1 1 4 4 4 1 RasGEF N-terminal motif Intein_splicing PF14890.6 PRP73185.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 Intein splicing domain Tubulin_C PF03953.17 PRP73185.1 - 0.11 12.6 1.8 0.49 10.6 1.8 2.1 1 0 0 1 1 1 0 Tubulin C-terminal domain Cas_DxTHG PF09455.10 PRP73185.1 - 3.3 7.2 8.5 1.6 8.2 3.8 2.3 2 0 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family Spc7 PF08317.11 PRP73185.1 - 6 5.6 33.8 1.4 7.7 5.9 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein Cupin_8 PF13621.6 PRP73186.1 - 1.6e-44 152.6 2.6 2.8e-44 151.7 2.6 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PRP73186.1 - 0.002 17.7 0.0 0.0044 16.5 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PRP73186.1 - 0.071 13.5 1.8 0.1 13.1 0.0 2.3 3 0 0 3 3 3 0 JmjC domain, hydroxylase Elf1 PF05129.13 PRP73187.1 - 0.46 10.6 2.6 0.68 10.0 0.1 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like G-alpha PF00503.20 PRP73188.1 - 2.1e-99 333.0 0.1 3.1e-99 332.5 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PRP73188.1 - 1.3e-13 50.8 0.3 6e-10 38.8 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP73188.1 - 6.4e-07 29.0 0.1 0.00073 19.0 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP73188.1 - 0.003 17.1 0.1 0.066 12.7 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP73188.1 - 0.02 14.9 0.0 0.38 10.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 PRP73188.1 - 0.042 14.1 0.2 5.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 PRP73188.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Ras PF00071.22 PRP73188.1 - 0.18 11.4 0.4 7.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Ras family Zn_clus PF00172.18 PRP73189.1 - 0.00023 21.2 15.1 0.00023 21.2 15.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3638 PF12340.8 PRP73189.1 - 0.017 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Metallophos PF00149.28 PRP73190.1 - 3.3e-31 109.4 0.1 4.9e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 PRP73190.1 - 8.2e-31 106.2 1.2 1.2e-30 105.6 0.3 1.8 2 0 0 2 2 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 PRP73190.1 - 1.5e-18 65.7 10.9 1.9e-07 30.6 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP73190.1 - 3e-12 45.7 14.5 5.9e-05 22.9 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP73190.1 - 3.7e-12 45.7 12.3 5.5e-05 22.8 1.9 3.4 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 PRP73190.1 - 2.5e-09 36.6 7.6 0.00058 19.9 0.1 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP73190.1 - 6.6e-09 35.6 4.6 0.00018 21.7 1.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP73190.1 - 3.1e-06 27.2 0.0 0.0044 17.1 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP73190.1 - 9.2e-06 25.9 2.6 0.00075 19.7 0.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP73190.1 - 3.7e-05 24.3 3.3 0.00018 22.1 1.5 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP73190.1 - 0.00029 21.4 0.4 0.21 12.5 0.0 3.6 2 1 2 4 4 3 1 Tetratricopeptide repeat Paf67 PF10255.9 PRP73190.1 - 0.00097 18.2 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_19 PF14559.6 PRP73190.1 - 0.0034 17.8 5.3 3.6 8.2 3.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP73190.1 - 0.0052 16.8 1.2 1.4 9.0 0.1 2.5 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat PDDEXK_3 PF13366.6 PRP73190.1 - 0.05 14.0 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF3856 PF12968.7 PRP73190.1 - 0.14 12.3 0.4 1.8 8.7 0.4 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 PRP73190.1 - 0.14 12.9 2.2 0.75 10.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPK2 PF03976.14 PRP73190.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) Cyclin_N2 PF16500.5 PRP73190.1 - 0.16 12.7 0.0 0.32 11.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of cyclin_N MIT PF04212.18 PRP73190.1 - 0.59 10.2 5.9 21 5.3 1.4 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain RTA1 PF04479.13 PRP73191.1 - 4.3e-67 225.7 5.1 9.1e-67 224.7 5.1 1.6 1 0 0 1 1 1 1 RTA1 like protein BAF250_C PF12031.8 PRP73191.1 - 0.052 12.8 1.5 3.1 7.0 0.1 2.8 2 1 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa DUF3605 PF12239.8 PRP73191.1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) FtsJ PF01728.19 PRP73192.1 - 3.6e-10 40.2 0.0 5.7e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 PRP73192.1 - 2.4e-08 33.9 0.0 5.4e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP73192.1 - 0.00011 22.9 0.0 0.00023 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP73192.1 - 0.00029 20.3 0.0 0.00055 19.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 PRP73192.1 - 0.00035 21.5 0.0 0.0053 17.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 PRP73192.1 - 0.0005 19.8 0.0 0.0033 17.1 0.0 2.0 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 PRP73192.1 - 0.0015 18.4 0.0 0.0039 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PRP73192.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 PRP73192.1 - 0.045 13.4 0.9 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Vps5 PF09325.10 PRP73193.1 - 8.1e-36 123.7 11.1 8.1e-36 123.7 11.1 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 PRP73193.1 - 1.9e-25 89.1 1.1 5.2e-25 87.6 1.1 1.8 1 0 0 1 1 1 1 PX domain MutS_III PF05192.18 PRP73193.1 - 0.015 15.6 0.8 6 7.0 0.0 2.2 2 0 0 2 2 2 0 MutS domain III BAR_3_WASP_bdg PF10456.9 PRP73193.1 - 0.021 14.3 4.9 0.034 13.6 4.9 1.3 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein HXXSHH PF07586.11 PRP73193.1 - 0.047 13.3 2.0 0.071 12.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Erf4 PF10256.9 PRP73193.1 - 0.058 13.5 0.1 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family UPF0242 PF06785.11 PRP73193.1 - 0.31 11.1 10.3 0.036 14.2 4.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus G8 PF10162.9 PRP73194.1 - 3.3e-20 72.4 0.2 9.3e-20 70.9 0.2 1.8 1 0 0 1 1 1 1 G8 domain DUF2190 PF09956.9 PRP73194.1 - 0.039 14.4 1.6 1.1 9.8 1.1 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2190) Ras PF00071.22 PRP73195.1 - 1e-45 155.3 0.1 1.3e-45 154.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP73195.1 - 3.9e-23 81.9 0.4 6.1e-23 81.3 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP73195.1 - 4.7e-08 32.7 0.0 6.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP73195.1 - 0.0029 17.2 0.6 0.15 11.6 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP73195.1 - 0.0041 16.5 0.1 0.0056 16.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 PRP73195.1 - 0.0099 16.2 0.0 0.037 14.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PRP73195.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PRP73195.1 - 0.031 14.8 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter RPA_interact_N PF14766.6 PRP73195.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal MMR_HSR1 PF01926.23 PRP73195.1 - 0.055 13.5 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATPase PF06745.13 PRP73195.1 - 0.067 12.5 0.1 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 KaiC RsgA_GTPase PF03193.16 PRP73195.1 - 0.095 12.6 0.0 9.9 6.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 PRP73195.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_38N PF01074.22 PRP73196.1 - 1.1e-70 238.3 10.4 2.3e-70 237.2 10.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Ank_2 PF12796.7 PRP73196.1 - 3e-49 165.5 6.5 1.1e-12 48.4 0.3 6.4 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP73196.1 - 2.2e-39 133.3 7.8 4.8e-05 23.8 0.0 9.2 6 3 3 9 9 8 8 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 PRP73196.1 - 7.8e-39 133.5 0.0 1.8e-37 129.1 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_3 PF13606.6 PRP73196.1 - 5.8e-35 115.3 5.9 0.0018 18.6 0.0 11.1 11 0 0 11 11 10 8 Ankyrin repeat Ank_5 PF13857.6 PRP73196.1 - 2.9e-33 113.5 8.8 7.3e-07 29.4 0.2 8.8 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Pkinase PF00069.25 PRP73196.1 - 9.6e-33 113.6 0.1 6.2e-31 107.7 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Ank PF00023.30 PRP73196.1 - 6.8e-27 92.7 5.4 0.00032 21.0 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat Glyco_hydro_38C PF07748.13 PRP73196.1 - 4e-22 79.4 1.1 6.8e-17 62.2 0.4 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP73196.1 - 7.8e-19 67.6 0.1 2.1e-18 66.3 0.1 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PRP73196.1 - 2.1e-06 27.7 0.0 6.3e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF4692 PF15763.5 PRP73196.1 - 0.0084 16.6 2.6 4.1 7.9 0.1 3.0 2 0 0 2 2 2 2 Regulator of human erythroid cell expansion (RHEX) DUF5535 PF17687.1 PRP73196.1 - 0.038 14.1 0.1 0.13 12.4 0.1 1.9 2 0 0 2 2 1 0 Family of unknown function (DUF5535) EGF_2 PF07974.13 PRP73197.1 - 0.007 16.7 5.0 0.019 15.3 5.0 1.7 1 0 0 1 1 1 1 EGF-like domain S_locus_glycop PF00954.20 PRP73197.1 - 0.025 15.1 1.8 0.055 14.0 1.8 1.6 1 0 0 1 1 1 0 S-locus glycoprotein domain GMC_oxred_N PF00732.19 PRP73198.1 - 3.6e-31 108.6 0.1 7.3e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP73198.1 - 8.4e-15 55.5 0.0 1.9e-14 54.4 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 PRP73198.1 - 0.00019 20.6 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 PRP73198.1 - 0.00092 19.4 0.7 0.0029 17.8 0.7 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PRP73198.1 - 0.019 14.2 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP73198.1 - 0.027 13.6 0.1 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 PRP73198.1 - 0.032 13.8 0.3 0.086 12.4 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP73198.1 - 0.16 10.7 0.2 0.39 9.4 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF1485 PF07364.12 PRP73198.1 - 0.2 10.9 0.0 0.59 9.4 0.0 1.8 1 1 1 2 2 2 0 Metallopeptidase family M81 Ras PF00071.22 PRP73199.1 - 2.6e-52 176.7 0.1 3.3e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP73199.1 - 9.9e-19 67.7 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP73199.1 - 1.9e-08 34.0 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP73199.1 - 0.00029 20.8 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 PRP73199.1 - 0.00068 19.7 0.0 0.00096 19.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP73199.1 - 0.00092 18.8 0.0 0.004 16.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain THF_DHG_CYH PF00763.23 PRP73200.1 - 2.5e-26 92.2 0.0 1.3e-25 89.9 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 PRP73200.1 - 3.6e-15 55.7 0.1 2.1e-10 40.2 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain zf-C2H2_2 PF12756.7 PRP73201.1 - 7.2e-28 96.9 16.5 3.8e-22 78.5 1.8 4.0 3 1 1 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 PRP73201.1 - 0.002 18.8 7.4 0.51 11.0 0.2 3.5 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats BIR PF00653.21 PRP73201.1 - 0.022 15.4 6.8 2 9.1 0.1 4.0 3 1 1 4 4 4 0 Inhibitor of Apoptosis domain DUF1349 PF07081.11 PRP73201.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) zf-C2H2_4 PF13894.6 PRP73201.1 - 0.29 12.1 31.2 0.15 13.0 1.1 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PRP73201.1 - 0.59 10.5 11.2 0.18 12.1 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-FLZ PF04570.14 PRP73201.1 - 2.2 7.9 12.1 0.19 11.2 0.3 3.6 4 0 0 4 4 4 0 zinc-finger of the FCS-type, C2-C2 zf-nanos PF05741.13 PRP73201.1 - 3 8.2 11.5 0.74 10.1 0.2 3.9 4 0 0 4 4 4 0 Nanos RNA binding domain PyrI_C PF02748.15 PRP73201.1 - 9.5 6.2 8.6 11 6.1 0.1 3.9 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain tRNA-synt_1 PF00133.22 PRP73203.1 - 1e-191 638.3 0.0 1.2e-190 634.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PRP73203.1 - 1.1e-32 113.1 0.3 2.8e-32 111.8 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PRP73203.1 - 2.1e-15 56.4 0.6 1.3e-08 34.0 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 PRP73203.1 - 3.9e-08 33.0 0.0 7.3e-06 25.6 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 PRP73203.1 - 3.3e-05 23.4 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 PRP73203.1 - 0.099 11.9 1.0 0.34 10.2 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Glyco_hydro_17 PF00332.18 PRP73204.1 - 1.8e-07 31.1 0.6 3.6e-06 26.8 0.6 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Abhydrolase_3 PF07859.13 PRP73205.1 - 2.4e-45 155.0 0.0 3.3e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PRP73205.1 - 2.3e-10 39.9 0.0 9.6e-10 37.9 0.0 1.8 1 1 1 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 PRP73205.1 - 0.0011 19.6 1.5 0.002 18.8 1.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 PRP73205.1 - 0.0071 15.3 0.0 0.087 11.7 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 PRP73205.1 - 0.088 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ferritin_2 PF13668.6 PRP73206.1 - 2.6e-39 134.5 15.6 3.4e-23 82.3 1.8 3.0 3 0 0 3 3 3 2 Ferritin-like domain SH2 PF00017.24 PRP73206.1 - 0.00033 20.7 0.0 0.00084 19.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Colicin_V PF02674.16 PRP73206.1 - 0.02 14.8 0.3 0.14 12.2 0.1 2.3 2 0 0 2 2 2 0 Colicin V production protein DUF5305 PF17231.2 PRP73206.1 - 0.058 12.8 0.1 0.058 12.8 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Romo1 PF10247.9 PRP73206.1 - 0.15 12.4 2.2 0.83 10.1 2.2 2.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF4064 PF13273.6 PRP73206.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) YabA PF06156.13 PRP73206.1 - 6.1 7.6 6.5 14 6.4 6.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA adh_short PF00106.25 PRP73207.1 - 4.5e-52 176.3 0.1 7.3e-52 175.7 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP73207.1 - 4.7e-34 118.0 0.0 6.3e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP73207.1 - 2e-12 47.4 0.4 7.4e-11 42.3 0.1 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 PRP73207.1 - 1.8e-05 24.0 0.4 7e-05 22.1 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 PRP73207.1 - 0.0013 18.3 0.0 0.0056 16.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP73207.1 - 0.0021 18.0 0.0 0.044 13.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Wax2_C PF12076.8 PRP73207.1 - 0.004 16.9 0.1 0.0066 16.2 0.1 1.4 1 0 0 1 1 1 1 WAX2 C-terminal domain F420_oxidored PF03807.17 PRP73207.1 - 0.0043 17.6 0.3 0.0098 16.5 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 PRP73207.1 - 0.01 16.1 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 PRP73207.1 - 0.026 14.1 0.1 0.076 12.7 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Helicase_RecD PF05127.14 PRP73207.1 - 0.095 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Helicase TrkA_N PF02254.18 PRP73207.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 PRP73207.1 - 0.27 10.8 1.5 0.76 9.3 0.2 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MFAP1 PF06991.11 PRP73208.1 - 3e-60 203.8 29.7 3e-60 203.8 29.7 3.0 1 1 2 3 3 3 1 Microfibril-associated/Pre-mRNA processing G8 PF10162.9 PRP73209.1 - 4.3e-22 78.5 4.4 4.4e-15 55.8 0.5 2.8 2 1 1 3 3 3 2 G8 domain DUF5378 PF17349.2 PRP73209.1 - 0.057 12.7 0.1 0.099 11.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5378) CorA PF01544.18 PRP73211.1 - 6.2e-08 32.3 1.1 8.9e-08 31.8 1.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Bac_globin PF01152.21 PRP73211.1 - 0.0042 17.2 0.2 0.078 13.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial-like globin RACo_C_ter PF14574.6 PRP73211.1 - 0.0099 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of RACo the ASKHA domain HNH_4 PF13395.6 PRP73215.1 - 0.036 14.0 0.1 0.049 13.6 0.1 1.5 1 1 0 1 1 1 0 HNH endonuclease DFF40 PF09230.10 PRP73215.1 - 0.14 11.7 0.4 0.23 11.1 0.2 1.3 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa CC2-LZ PF16516.5 PRP73217.1 - 0.024 15.0 3.6 0.024 15.0 3.6 2.9 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator OmpH PF03938.14 PRP73220.1 - 0.37 11.1 12.9 0.47 10.8 10.3 2.2 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) FadA PF09403.10 PRP73220.1 - 0.47 11.0 11.2 0.87 10.1 0.2 3.4 2 1 1 3 3 3 0 Adhesion protein FadA DUF4407 PF14362.6 PRP73220.1 - 3.2 7.0 7.2 4.5 6.5 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) D-ser_dehydrat PF14031.6 PRP73222.1 - 0.08 13.6 0.2 0.093 13.4 0.2 1.2 1 0 0 1 1 1 0 Putative serine dehydratase domain DDE_3 PF13358.6 PRP73223.1 - 0.00094 18.9 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease MA3 PF02847.17 PRP73224.1 - 2.6e-05 24.1 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 2 MA3 domain CsgA PF17334.2 PRP73224.1 - 0.014 16.1 0.7 20 6.0 0.1 3.2 2 1 1 3 3 3 0 Minor curli fiber component A IDO PF01231.18 PRP73224.1 - 0.015 14.1 0.8 2.7 6.7 0.1 2.2 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase DUF3613 PF12266.8 PRP73224.1 - 0.028 14.2 0.3 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) DUF2087 PF09860.9 PRP73224.1 - 0.051 13.7 0.1 23 5.2 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Glycos_trans_3N PF02885.17 PRP73224.1 - 0.063 13.1 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain CSRNP_N PF16019.5 PRP73224.1 - 0.11 12.4 0.6 7.7 6.4 0.0 2.6 2 1 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus RecQ_Zn_bind PF16124.5 PRP73225.1 - 7.6e-11 42.6 4.3 1.9e-10 41.3 4.3 1.7 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 PRP73225.1 - 3.7e-06 26.7 0.1 0.0001 22.0 0.1 2.4 1 1 0 1 1 1 1 RQC domain HRDC PF00570.23 PRP73225.1 - 0.0019 18.1 0.0 0.024 14.6 0.0 2.4 2 0 0 2 2 2 1 HRDC domain DNA_pol_B_2 PF03175.13 PRP73227.1 - 1.7e-06 27.2 0.0 2.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral RasGAP PF00616.19 PRP73229.1 - 4.1e-12 46.3 0.0 8.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Nod1 PF17114.5 PRP73229.1 - 0.011 15.9 0.5 4.4 7.5 0.2 2.4 1 1 1 2 2 2 0 Gef2-related medial cortical node protein Nod1 RVT_1 PF00078.27 PRP73233.1 - 6.1e-73 245.0 8.0 1.4e-26 93.4 0.3 3.3 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Mob1_phocein PF03637.17 PRP73233.1 - 4.3e-05 23.6 2.0 5 7.1 0.1 3.7 4 0 0 4 4 3 3 Mob1/phocein family gag-asp_proteas PF13975.6 PRP73233.1 - 4.5e-05 23.9 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PRP73233.1 - 0.00056 20.5 0.0 0.0016 19.1 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease EABR PF12180.8 PRP73233.1 - 0.0012 18.4 8.0 4.5 7.0 0.2 3.9 3 0 0 3 3 3 3 TSG101 and ALIX binding domain of CEP55 Csm2_III-A PF03750.13 PRP73233.1 - 0.0021 18.9 1.4 37 5.2 0.0 3.5 3 0 0 3 3 3 0 Csm2 Type III-A SHQ1 PF04925.15 PRP73233.1 - 0.0072 15.9 8.6 8.2 6.0 0.1 4.0 4 0 0 4 4 4 3 SHQ1 protein DUF1554 PF07588.11 PRP73233.1 - 0.032 14.0 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1554) SLBB PF10531.9 PRP73233.1 - 0.081 12.8 0.0 1.1e+02 2.8 0.0 3.3 3 0 0 3 3 3 0 SLBB domain RVP_2 PF08284.11 PRP73233.1 - 0.12 12.2 0.0 0.38 10.5 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Rdx PF10262.9 PRP73233.1 - 0.15 12.3 0.1 1.7e+02 2.5 0.0 3.6 3 0 0 3 3 3 0 Rdx family DUF2024 PF09630.10 PRP73233.1 - 0.62 10.0 3.2 1.1e+02 2.8 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) ATP_transf PF09830.9 PRP73234.1 - 6.8e-09 35.7 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 PRP73234.1 - 2.1e-06 27.2 0.3 1.4e-05 24.5 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 PRP73234.1 - 0.009 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) EOS1 PF12326.8 PRP73234.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 N-glycosylation protein ERM PF00769.19 PRP73237.1 - 0.45 10.3 35.3 0.22 11.3 1.9 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 PRP73237.1 - 1.2 7.9 23.8 1.7 7.5 23.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 PRP73237.1 - 6.8 6.9 28.1 12 6.1 26.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 PRP73237.1 - 9 6.1 24.2 0.76 9.6 16.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) rve PF00665.26 PRP73245.1 - 1.1e-09 38.5 0.0 1.6e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Methyltr_RsmF_N PF17125.5 PRP73247.1 - 0.029 14.9 1.4 2.1 8.9 0.1 3.3 3 0 0 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF DUF4286 PF14114.6 PRP73247.1 - 0.18 12.3 1.5 3.8 8.1 0.9 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) DDE_Tnp_4 PF13359.6 PRP73248.1 - 1.2e-24 86.7 0.0 1.4e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP73248.1 - 2.1e-05 24.3 0.0 3.2e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 PRP73248.1 - 0.12 12.7 0.1 0.32 11.4 0.1 1.8 1 1 0 1 1 1 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 PRP73249.1 - 1.1e-11 44.6 0.0 1e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease SEC-C PF02810.15 PRP73251.1 - 6.8e-06 25.9 7.3 6.8e-06 25.9 7.3 1.7 2 0 0 2 2 2 1 SEC-C motif PIF1 PF05970.14 PRP73252.1 - 2.5e-57 194.7 0.0 7.1e-45 153.7 0.0 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 PRP73252.1 - 3.7e-20 72.5 0.0 6.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain zf-PARP PF00645.18 PRP73252.1 - 1.8e-17 63.9 1.2 1.8e-17 63.9 1.2 2.9 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AAA_19 PF13245.6 PRP73252.1 - 5.4e-13 49.5 0.1 1.2e-12 48.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 PRP73252.1 - 4.5e-06 27.0 0.0 1.8e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PRP73252.1 - 0.00041 20.2 0.1 0.003 17.3 0.1 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 PRP73252.1 - 0.0063 16.6 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 PRP73252.1 - 0.015 15.8 0.0 0.015 15.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 PRP73252.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 PRP73252.1 - 0.034 13.9 1.5 0.059 13.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 PRP73252.1 - 0.034 13.2 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 PRP73252.1 - 0.035 13.9 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP73252.1 - 0.038 14.4 0.1 0.092 13.1 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PRP73252.1 - 0.069 13.7 0.0 0.069 13.7 0.0 2.9 4 0 0 4 4 2 0 ABC transporter AAA PF00004.29 PRP73252.1 - 0.071 13.5 0.2 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SH3_13 PF18335.1 PRP73252.1 - 0.072 12.9 0.0 0.27 11.1 0.0 2.0 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain dsDNA_bind PF01984.20 PRP73253.1 - 3.7e-30 104.5 6.6 4.3e-30 104.2 6.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4953 PF16313.5 PRP73253.1 - 0.02 14.1 0.4 0.022 14.0 0.4 1.1 1 0 0 1 1 1 0 Met-zincin XdhC_CoxI PF02625.16 PRP73253.1 - 0.15 12.3 0.4 0.34 11.1 0.2 1.9 1 1 1 2 2 2 0 XdhC and CoxI family Phosphorylase PF00343.20 PRP73254.1 - 7.6e-302 1002.9 0.0 9.7e-302 1002.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Frag1 PF10277.9 PRP73256.1 - 1.4e-12 47.6 12.7 2e-12 47.1 12.7 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family MWFE PF15879.5 PRP73256.1 - 0.17 12.1 0.8 0.44 10.7 0.8 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF21 PF01595.20 PRP73256.1 - 4.7 6.9 7.4 0.36 10.5 0.3 2.5 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Pkinase_Tyr PF07714.17 PRP73257.1 - 3e-27 95.6 0.0 1.1e-26 93.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP73257.1 - 4e-19 69.0 0.0 1e-18 67.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP73257.1 - 5e-14 51.8 37.5 4.2e-07 29.6 10.4 4.3 2 1 2 4 4 4 4 Leucine rich repeat GPS PF01825.21 PRP73257.1 - 2.6e-10 40.7 1.8 5.7e-10 39.6 1.8 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP73257.1 - 1.2e-08 35.1 41.7 0.0016 18.8 3.6 5.7 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP73257.1 - 0.018 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LRR_1 PF00560.33 PRP73257.1 - 1.1 10.1 32.5 4.2 8.3 0.5 8.3 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 PRP73257.1 - 5.1 6.6 5.8 5.4 6.5 2.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeat Adeno_E3_CR2 PF02439.15 PRP73257.1 - 7.2 6.5 8.6 20 5.0 8.6 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DNA_primase_lrg PF04104.14 PRP73258.1 - 0.037 13.4 0.7 0.048 13.1 0.7 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Colicin-DNase PF12639.7 PRP73258.1 - 0.063 14.1 0.4 1.2 10.0 0.0 2.3 2 1 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DUF16 PF01519.16 PRP73258.1 - 0.21 12.1 2.2 0.31 11.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Filament PF00038.21 PRP73259.1 - 0.0026 17.4 16.6 0.0026 17.4 16.6 1.9 1 1 1 2 2 2 2 Intermediate filament protein ERM PF00769.19 PRP73259.1 - 0.04 13.7 33.3 0.053 13.3 33.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 PRP73259.1 - 0.15 12.2 35.9 2.9 8.0 10.8 3.8 1 1 2 3 3 3 0 Tropomyosin like FPP PF05911.11 PRP73259.1 - 0.2 9.8 31.6 0.057 11.6 27.5 1.8 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF3584 PF12128.8 PRP73259.1 - 0.25 8.8 23.7 0.32 8.5 23.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4047 PF13256.6 PRP73259.1 - 0.61 10.3 10.0 1.4 9.1 7.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Fez1 PF06818.15 PRP73259.1 - 4.8 7.6 32.7 2.5 8.5 21.3 2.2 1 1 1 2 2 2 0 Fez1 DUF4449 PF14613.6 PRP73259.1 - 8.7 6.4 11.5 11 6.1 6.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) Claudin_2 PF13903.6 PRP73261.1 - 0.0037 17.0 2.3 0.0063 16.3 2.3 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Claudin_3 PF06653.11 PRP73261.1 - 0.12 12.3 6.8 1.8 8.4 6.8 2.1 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF1700 PF08006.11 PRP73261.1 - 7.7 6.0 8.2 15 5.1 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Vinculin PF01044.19 PRP73263.1 - 3.8e-13 48.6 15.7 2.2e-11 42.8 11.3 2.2 1 1 1 2 2 2 2 Vinculin family T3SchapCesA PF11439.8 PRP73263.1 - 0.043 14.0 0.9 0.043 14.0 0.9 2.5 2 1 2 4 4 4 0 Type III secretion system filament chaperone CesA HTH_47 PF16221.5 PRP73263.1 - 0.13 11.9 0.2 0.38 10.3 0.2 1.8 1 0 0 1 1 1 0 winged helix-turn-helix ANAPC1 PF12859.7 PRP73265.1 - 0.061 13.9 0.9 0.13 12.8 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Thg1C PF14413.6 PRP73266.1 - 9e-05 22.6 0.1 0.14 12.3 0.0 2.3 2 0 0 2 2 2 2 Thg1 C terminal domain DUF1150 PF06620.11 PRP73266.1 - 0.0012 19.0 0.3 1.7 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1150) DUF4362 PF14275.6 PRP73266.1 - 0.007 16.6 0.0 6.3 7.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4362) IL7 PF01415.16 PRP73266.1 - 0.011 15.7 0.2 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Interleukin 7/9 family SPACA9 PF15120.6 PRP73266.1 - 0.018 14.8 0.5 5.1 6.8 0.1 2.3 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 Fes1 PF08609.10 PRP73266.1 - 0.037 14.9 0.0 19 6.2 0.0 2.8 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Terminase_3 PF04466.13 PRP73267.1 - 0.03 13.8 0.1 5.6 6.4 0.0 2.2 2 0 0 2 2 2 0 Phage terminase large subunit COesterase PF00135.28 PRP73268.1 - 1.4e-72 245.2 0.0 2.2e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP73268.1 - 0.00083 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP73268.1 - 0.013 15.0 0.1 0.029 13.8 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family PsaX PF08078.12 PRP73270.1 - 0.051 13.6 0.4 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 PsaX family zf-C2H2_4 PF13894.6 PRP73270.1 - 0.13 13.2 4.1 0.23 12.4 1.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 PRP73270.1 - 0.82 9.8 7.4 0.32 11.1 1.0 2.6 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type rve PF00665.26 PRP73271.1 - 6.8e-08 32.7 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Carb_bind PF10645.9 PRP73274.1 - 2.4e-09 37.3 17.0 1.7e-06 28.1 4.1 2.6 1 1 1 2 2 2 2 Carbohydrate binding FSA_C PF10479.9 PRP73274.1 - 9.6 4.2 11.7 12 3.9 11.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RicinB_lectin_2 PF14200.6 PRP73275.1 - 0.001 19.7 4.8 0.011 16.5 0.5 3.3 2 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 PRP73275.1 - 0.065 13.5 0.5 0.72 10.1 0.1 2.3 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain NUFIP1 PF10453.9 PRP73276.1 - 6.1e-09 35.6 0.2 6.1e-09 35.6 0.2 2.8 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Asp_protease_2 PF13650.6 PRP73276.1 - 6e-07 30.0 0.0 0.06 14.0 0.0 3.1 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 PRP73276.1 - 7.3e-05 23.3 0.0 0.66 10.6 0.0 2.8 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease CAP PF00188.26 PRP73276.1 - 0.00091 20.1 0.4 4.9 8.0 0.0 3.4 3 0 0 3 3 3 2 Cysteine-rich secretory protein family Peptidase_A2E PF12382.8 PRP73276.1 - 0.012 15.6 0.0 9.1 6.3 0.0 2.8 2 0 0 2 2 2 0 Retrotransposon peptidase GATase_2 PF00310.21 PRP73276.1 - 0.049 12.3 0.0 8.7 4.9 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferases class-II RVP PF00077.20 PRP73276.1 - 0.14 12.5 0.1 28 5.1 0.0 2.7 2 0 0 2 2 2 0 Retroviral aspartyl protease RT_RNaseH PF17917.1 PRP73277.1 - 7e-39 132.3 0.4 1.3e-25 89.7 0.0 4.3 4 1 1 5 5 5 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP73277.1 - 1.1e-35 123.2 4.6 1.4e-19 70.5 0.2 3.6 3 1 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PRP73277.1 - 7.6e-35 118.9 0.0 5.3e-24 84.2 0.0 4.1 4 1 1 5 5 3 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP73277.1 - 3.6e-18 65.4 0.1 1.4e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain zf-H2C2 PF09337.10 PRP73277.1 - 3.8e-16 59.0 1.7 3.5e-07 30.3 0.0 3.6 3 0 0 3 3 3 2 H2C2 zinc finger Asp_protease_2 PF13650.6 PRP73277.1 - 4.2e-05 24.1 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Integrase_Zn PF02022.19 PRP73277.1 - 0.00018 21.4 15.4 0.031 14.2 3.1 3.0 2 1 0 2 2 2 2 Integrase Zinc binding domain gag-asp_proteas PF13975.6 PRP73277.1 - 0.00083 19.9 0.0 0.0019 18.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 PRP73277.1 - 0.0073 16.2 4.4 2.1 8.4 0.4 2.8 2 0 0 2 2 2 2 Zinc knuckle PHP_C PF13263.6 PRP73277.1 - 0.026 14.3 0.1 4.6 7.1 0.0 2.7 2 0 0 2 2 2 0 PHP-associated DUF3618 PF12277.8 PRP73277.1 - 0.027 14.7 0.0 10 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) zf-NADH-PPase PF09297.11 PRP73277.1 - 0.066 12.9 1.1 60 3.4 0.0 4.4 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain zf-C2H2_10 PF16588.5 PRP73277.1 - 0.077 12.7 8.7 2.3 8.0 1.2 2.7 2 0 0 2 2 2 0 C2H2 zinc-finger Asp_protease PF09668.10 PRP73277.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease JTB PF05439.12 PRP73277.1 - 0.29 11.2 4.7 7.9 6.6 0.4 3.2 3 0 0 3 3 2 0 Jumping translocation breakpoint protein (JTB) CRF-BP PF05428.11 PRP73277.1 - 0.55 9.0 1.8 18 4.0 0.1 2.2 2 0 0 2 2 2 0 Corticotropin-releasing factor binding protein (CRF-BP) TetR_C_17 PF17922.1 PRP73278.1 - 0.024 14.7 0.3 0.045 13.8 0.3 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NRDE-2 PF08424.10 PRP73278.1 - 0.084 12.0 2.0 0.12 11.5 2.0 1.4 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF4286 PF14114.6 PRP73278.1 - 0.1 13.1 1.5 0.16 12.5 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) rve PF00665.26 PRP73279.1 - 1.1e-12 48.2 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain RRP14 PF15459.6 PRP73280.1 - 0.0013 19.3 2.3 0.56 10.9 0.2 2.5 2 0 0 2 2 2 2 60S ribosome biogenesis protein Rrp14 DUF2161 PF09929.9 PRP73280.1 - 0.0076 16.4 0.2 3.4 7.8 0.0 2.3 1 1 1 2 2 2 2 Putative PD-(D/E)XK phosphodiesterase (DUF2161) DUF3243 PF11588.8 PRP73280.1 - 0.014 15.7 0.0 6.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) Sec5 PF15469.6 PRP73280.1 - 0.026 14.3 2.1 3.3 7.5 0.6 2.3 1 1 1 2 2 2 0 Exocyst complex component Sec5 Cadherin_2 PF08266.12 PRP73280.1 - 0.075 12.9 0.7 1.6 8.6 0.2 2.5 2 0 0 2 2 2 0 Cadherin-like Endothelin PF00322.17 PRP73280.1 - 0.76 9.4 3.4 1.8 8.2 3.4 1.6 1 0 0 1 1 1 0 Endothelin family Dynamin_M PF01031.20 PRP73281.1 - 0.02 14.1 0.3 0.02 14.1 0.3 2.1 2 0 0 2 2 2 0 Dynamin central region Paz_1 PF18349.1 PRP73281.1 - 0.061 13.3 0.7 1.3 9.0 0.0 2.8 2 1 1 3 3 3 0 PAZ domain DUF5071 PF16804.5 PRP73282.1 - 0.00051 20.3 0.5 1.6 9.0 0.0 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF5071) SpoIISA_toxin PF14171.6 PRP73282.1 - 0.002 17.9 0.6 0.53 9.9 0.2 2.2 1 1 1 2 2 2 2 Toxin SpoIISA, type II toxin-antitoxin system FANCI_HD2 PF14680.6 PRP73282.1 - 0.021 14.1 0.1 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 FANCI helical domain 2 Iso_dh PF00180.20 PRP73282.1 - 0.037 13.2 0.3 0.7 9.0 0.0 2.0 2 0 0 2 2 2 0 Isocitrate/isopropylmalate dehydrogenase MIS13 PF08202.11 PRP73283.1 - 0.021 14.1 0.7 1.6 7.9 0.5 2.1 2 0 0 2 2 2 0 Mis12-Mtw1 protein family Dynamin_M PF01031.20 PRP73283.1 - 0.049 12.8 0.3 0.081 12.1 0.3 1.3 1 0 0 1 1 1 0 Dynamin central region MHB PF16525.5 PRP73283.1 - 0.084 13.1 1.7 1.9 8.8 1.0 2.7 2 1 1 3 3 3 0 Haemophore, haem-binding V_ATPase_I PF01496.19 PRP73287.1 - 0.0042 15.1 0.4 0.0048 14.9 0.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ran-binding PF05508.11 PRP73287.1 - 0.062 12.3 1.4 0.08 11.9 1.4 1.1 1 0 0 1 1 1 0 RanGTP-binding protein Ribosomal_S24e PF01282.19 PRP73287.1 - 0.094 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S24e DUF5130 PF17174.4 PRP73293.1 - 0.0012 19.0 0.0 0.76 10.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5130) Popeye PF04831.13 PRP73293.1 - 0.29 11.3 1.9 0.5 10.5 1.9 1.3 1 0 0 1 1 1 0 Popeye protein conserved region Rota_NS26 PF01525.16 PRP73295.1 - 0.087 12.8 0.0 0.093 12.7 0.0 1.0 1 0 0 1 1 1 0 Rotavirus NS26 RasGEF_N PF00618.20 PRP73300.1 - 2.4e-10 40.6 0.4 5.3e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 RasGEF N-terminal motif AATF-Che1 PF13339.6 PRP73300.1 - 0.015 16.0 2.0 0.61 10.8 1.9 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor KorB PF08535.10 PRP73303.1 - 0.04 14.0 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 KorB domain WD40 PF00400.32 PRP73304.1 - 3.4e-10 40.3 0.1 1.9e-09 38.0 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat FPP PF05911.11 PRP73304.1 - 0.0079 14.5 0.2 0.011 14.0 0.2 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil bZIP_1 PF00170.21 PRP73304.1 - 0.023 14.8 1.8 0.043 13.9 1.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor Cast PF10174.9 PRP73304.1 - 0.036 12.3 0.3 0.045 12.0 0.3 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone KIAA1430 PF13879.6 PRP73304.1 - 0.053 14.3 0.6 0.088 13.6 0.6 1.4 1 0 0 1 1 1 0 KIAA1430 homologue Med10 PF09748.9 PRP73304.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DivIC PF04977.15 PRP73304.1 - 0.18 11.6 1.4 0.29 10.9 1.4 1.3 1 0 0 1 1 1 0 Septum formation initiator Cofilin_ADF PF00241.20 PRP73306.1 - 0.051 13.4 0.0 0.064 13.1 0.0 1.1 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein TcdB_N PF12918.7 PRP73309.1 - 0.42 10.9 5.4 4.6 7.6 0.8 2.5 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Ribosomal_L36e PF01158.18 PRP73309.1 - 7.2 6.9 14.6 7.2 6.9 5.6 2.4 2 0 0 2 2 2 0 Ribosomal protein L36e MttA_Hcf106 PF02416.16 PRP73309.1 - 7.7 5.9 11.5 13 5.2 2.0 2.6 2 0 0 2 2 2 0 mttA/Hcf106 family Cwf_Cwc_15 PF04889.12 PRP73310.1 - 0.028 14.2 9.2 0.036 13.8 9.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.9 PRP73310.1 - 0.32 11.5 4.6 0.42 11.1 4.6 1.3 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 PRP73310.1 - 0.37 10.1 6.4 0.34 10.2 6.4 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 PRP73310.1 - 0.74 9.1 6.3 0.75 9.1 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein IL12p40_C PF10420.9 PRP73313.1 - 0.13 12.8 0.7 0.37 11.3 0.2 1.9 2 0 0 2 2 2 0 Cytokine interleukin-12p40 C-terminus FAM91_N PF14647.6 PRP73314.1 - 4e-66 223.4 4.6 4.5e-66 223.2 4.6 1.0 1 0 0 1 1 1 1 FAM91 N-terminus PB1 PF00564.24 PRP73317.1 - 2.1e-08 34.0 0.0 3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 PB1 domain PRiA4_ORF3 PF07929.11 PRP73317.1 - 0.086 12.5 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein HIRAN PF08797.11 PRP73318.1 - 0.0057 16.6 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain DUF2735 PF10931.8 PRP73318.1 - 0.12 13.1 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2735) GFA PF04828.14 PRP73320.1 - 2.8e-22 78.9 0.2 4.1e-22 78.3 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 PRP73320.1 - 0.049 13.7 1.6 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 PRP73320.1 - 0.1 12.0 0.6 0.21 11.0 0.2 1.7 2 0 0 2 2 2 0 NMD3 family Nudix_N_2 PF14803.6 PRP73320.1 - 0.89 9.5 0.1 0.89 9.5 0.1 2.9 3 0 0 3 3 3 0 Nudix N-terminal RNase_H PF00075.24 PRP73323.1 - 0.0009 19.4 0.0 0.00096 19.4 0.0 1.1 1 0 0 1 1 1 1 RNase H Ank_3 PF13606.6 PRP73324.1 - 0.0017 18.7 0.0 9.9 7.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 PRP73324.1 - 0.0074 16.8 0.0 11 6.7 0.0 4.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) DUF3253 PF11625.8 PRP73329.1 - 0.089 13.0 1.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) EF-hand_7 PF13499.6 PRP73330.1 - 7.4e-12 45.6 0.2 7.3e-07 29.5 0.1 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PRP73330.1 - 1.3e-10 40.3 1.8 8.3e-05 22.2 0.0 4.4 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 PRP73330.1 - 9e-10 37.4 1.1 7.5e-05 22.0 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PRP73330.1 - 2e-06 27.6 3.6 0.00036 20.3 0.1 4.2 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP73330.1 - 0.00012 21.5 1.0 0.00092 18.6 0.1 2.5 2 0 0 2 2 2 1 EF hand Chromo PF00385.24 PRP73331.1 - 1.1e-12 47.7 0.3 2.1e-12 46.7 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain S1_2 PF13509.6 PRP73331.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 S1 domain G8 PF10162.9 PRP73332.1 - 0.0022 18.0 0.2 0.29 11.2 0.2 2.2 1 1 1 2 2 2 2 G8 domain SLD5_C PF16922.5 PRP73335.1 - 0.0023 18.1 0.3 0.15 12.2 0.0 3.1 3 0 0 3 3 3 1 DNA replication complex GINS protein SLD5 C-terminus PAN_4 PF14295.6 PRP73336.1 - 6e-17 61.3 20.6 2.5e-10 40.1 6.0 2.5 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 PRP73336.1 - 1.1e-09 38.1 5.9 0.0001 22.2 1.3 2.3 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PRP73336.1 - 6.6e-07 29.4 12.1 0.0012 19.0 1.5 2.4 2 0 0 2 2 2 2 PAN-like domain Kelch_4 PF13418.6 PRP73337.1 - 3.9e-40 135.6 13.7 3.6e-08 33.3 0.1 7.2 6 1 1 7 7 7 7 Galactose oxidase, central domain Kelch_3 PF13415.6 PRP73337.1 - 1.3e-34 117.8 6.4 6.6e-07 29.5 0.0 6.6 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP73337.1 - 5.4e-34 115.4 9.5 3e-06 27.3 0.8 7.0 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PRP73337.1 - 2.5e-30 103.8 5.4 3.3e-06 26.6 0.0 7.2 7 0 0 7 7 7 6 Kelch motif Kelch_5 PF13854.6 PRP73337.1 - 1.5e-29 101.5 3.8 4e-05 23.5 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_2 PF07646.15 PRP73337.1 - 2.8e-18 65.1 10.3 0.00074 19.4 0.0 7.0 6 1 0 6 6 6 4 Kelch motif Peptidase_M41 PF01434.18 PRP73340.1 - 6.7e-47 159.8 2.5 8.7e-47 159.4 2.5 1.1 1 0 0 1 1 1 1 Peptidase family M41 DUF4866 PF16160.5 PRP73340.1 - 0.19 11.0 1.0 0.75 9.1 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4866) Chromo PF00385.24 PRP73341.1 - 4.2e-13 49.0 0.0 7.1e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Troponin-I_N PF11636.8 PRP73341.1 - 0.012 15.5 3.0 2.5 8.1 0.1 2.4 2 0 0 2 2 2 0 Troponin I residues 1-32 Mtf2_C PF14061.6 PRP73341.1 - 0.066 13.4 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Fic PF02661.18 PRP73342.1 - 1e-06 29.5 0.1 7.3e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family CSN4_RPN5_eIF3a PF18420.1 PRP73343.1 - 0.00062 19.9 0.0 0.0067 16.6 0.1 2.1 2 0 0 2 2 2 1 CSN4/RPN5/eIF3a helix turn helix domain DUF5344 PF17279.2 PRP73343.1 - 0.029 14.9 0.6 5.2 7.7 0.2 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DUF1251 PF06856.11 PRP73343.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) SAP PF02037.27 PRP73344.1 - 8.2e-14 51.0 0.4 4.4e-07 29.5 0.2 2.2 2 0 0 2 2 2 2 SAP domain LETM1 PF07766.13 PRP73344.1 - 0.00055 19.4 0.2 0.0029 17.0 0.2 1.8 1 1 0 1 1 1 1 LETM1-like protein Telomere_Sde2_2 PF13297.6 PRP73344.1 - 0.00062 19.4 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 2 Telomere stability C-terminal RNase_H PF00075.24 PRP73345.1 - 0.0001 22.5 0.8 0.007 16.5 0.0 2.9 2 1 0 2 2 2 1 RNase H zf-RVT PF13966.6 PRP73345.1 - 0.042 14.6 0.2 0.11 13.2 0.2 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase FtsX PF02687.21 PRP73346.1 - 0.041 14.3 0.1 0.046 14.2 0.1 1.1 1 0 0 1 1 1 0 FtsX-like permease family Chromo PF00385.24 PRP73349.1 - 1.5e-13 50.4 0.0 1.8e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5344 PF17279.2 PRP73350.1 - 0.092 13.3 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Fer4_10 PF13237.6 PRP73351.1 - 0.014 15.5 0.1 0.024 14.8 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-C3HC4_3 PF13920.6 PRP73353.1 - 0.019 14.8 5.9 0.019 14.8 5.9 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) K_channel_TID PF07941.11 PRP73353.1 - 0.032 14.7 0.4 0.032 14.7 0.4 1.9 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Prok-RING_4 PF14447.6 PRP73353.1 - 0.048 13.5 1.3 0.048 13.5 1.3 2.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP73353.1 - 0.38 10.8 5.5 0.14 12.1 1.0 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Cytochrom_c3_2 PF14537.6 PRP73353.1 - 3.3 8.2 9.2 0.33 11.4 4.4 1.8 2 0 0 2 2 2 0 Cytochrome c3 Ank_2 PF12796.7 PRP73360.1 - 6e-10 39.6 0.0 1.5e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP73360.1 - 7e-07 29.1 1.7 0.76 10.5 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat F-box PF00646.33 PRP73360.1 - 9.6e-07 28.5 0.3 2.5e-06 27.2 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP73360.1 - 1.1e-06 28.4 0.4 3.3e-06 26.9 0.4 1.8 1 0 0 1 1 1 1 F-box-like Ank_5 PF13857.6 PRP73360.1 - 6.2e-05 23.2 0.6 0.78 10.1 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) F-box_5 PF18511.1 PRP73360.1 - 0.007 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box Ank_4 PF13637.6 PRP73360.1 - 0.0089 16.6 0.7 4 8.2 0.0 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP73360.1 - 0.034 14.6 0.4 23 5.6 0.0 3.6 5 0 0 5 5 5 0 Ankyrin repeat Glyco_transf_18 PF15024.6 PRP73360.1 - 0.074 11.6 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 18 zf-FPG_IleRS PF06827.14 PRP73362.1 - 0.012 15.5 1.6 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS TEX13 PF15186.6 PRP73363.1 - 2.2e-07 30.7 3.9 12 5.6 0.0 6.4 7 0 0 7 7 7 4 Testis-expressed sequence 13 protein family Annexin_like PF18411.1 PRP73363.1 - 2.6e-05 24.4 4.4 97 3.3 0.0 7.7 7 0 0 7 7 7 0 Annexin-like domain Invas_SpaK PF03519.14 PRP73363.1 - 0.00024 21.1 2.8 22 5.2 0.0 5.7 6 0 0 6 6 6 0 Invasion protein B family DUF503 PF04456.12 PRP73363.1 - 0.00054 19.8 10.5 24 4.9 0.0 6.8 8 0 0 8 8 8 0 Protein of unknown function (DUF503) Mak10 PF04112.13 PRP73363.1 - 0.0057 16.2 11.1 82 2.7 0.0 6.9 7 0 0 7 7 7 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TssO PF17561.2 PRP73363.1 - 0.0096 16.0 17.8 19 5.3 0.1 8.0 8 0 0 8 8 8 0 Type VI secretion system, TssO DUF3303 PF11746.8 PRP73363.1 - 0.045 14.0 0.1 3.6e+02 1.5 0.0 5.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3303) Sulf_transp PF04143.14 PRP73363.1 - 0.076 12.6 24.6 3.2 7.2 0.1 7.7 9 1 0 9 9 9 0 Sulphur transport Plasmo_rep PF12135.8 PRP73363.1 - 0.11 12.1 3.9 2.4e+02 1.4 0.0 5.6 6 0 0 6 6 6 0 Plasmodium repeat family DUF5080 PF16883.5 PRP73363.1 - 0.23 11.5 12.2 3.8 7.6 0.2 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF5080) Peptidase_S74 PF13884.6 PRP73363.1 - 7.9 6.9 18.6 2e+02 2.4 0.0 7.6 7 0 0 7 7 7 0 Chaperone of endosialidase DUF5020 PF16412.5 PRP73365.1 - 0.0094 15.8 0.4 0.015 15.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5020) HMGL-like PF00682.19 PRP73365.1 - 0.047 13.3 0.3 0.069 12.7 0.3 1.3 1 0 0 1 1 1 0 HMGL-like DUF3292 PF11696.8 PRP73368.1 - 0.031 12.7 0.2 0.037 12.4 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) UCH PF00443.29 PRP73370.1 - 6.6e-28 97.9 5.9 1e-16 61.2 1.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP73370.1 - 8e-10 38.8 1.5 1.2e-05 25.0 0.5 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pput2613-deam PF14427.6 PRP73370.1 - 0.082 12.8 0.5 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Pput_2613-like deaminase HCV_NS1 PF01560.17 PRP73370.1 - 0.15 10.8 0.1 4 6.0 0.0 2.6 2 2 1 3 3 3 0 Hepatitis C virus non-structural protein E2/NS1 Pkinase_Tyr PF07714.17 PRP73371.1 - 1.2e-59 201.7 0.0 1.5e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP73371.1 - 1.5e-36 126.2 0.0 1.9e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP73371.1 - 0.026 13.9 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP73371.1 - 0.032 13.0 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase AMP-binding PF00501.28 PRP73375.1 - 3.8e-32 111.4 0.0 4.3e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 PRP73375.1 - 0.096 11.5 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter MIP PF00230.20 PRP73376.1 - 1.5e-63 214.6 20.3 1.2e-60 205.1 16.2 2.0 1 1 1 2 2 2 2 Major intrinsic protein MIP PF00230.20 PRP73377.1 - 1.2e-62 211.6 17.6 1.6e-62 211.2 17.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein TPR_21 PF09976.9 PRP73379.1 - 0.00097 18.9 0.5 0.003 17.3 0.1 2.0 1 1 0 2 2 2 1 Tetratricopeptide repeat-like domain T3SSipB PF16535.5 PRP73379.1 - 0.0022 18.5 0.2 0.0035 17.8 0.2 1.3 1 0 0 1 1 1 1 Type III cell invasion protein SipB DASH_Duo1 PF08651.10 PRP73379.1 - 0.01 15.6 0.3 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 DASH complex subunit Duo1 HsbA PF12296.8 PRP73379.1 - 0.016 15.6 0.5 0.029 14.8 0.5 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Laminin_II PF06009.12 PRP73379.1 - 0.016 15.2 0.6 0.03 14.4 0.6 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF4398 PF14346.6 PRP73379.1 - 0.032 14.9 3.1 0.053 14.1 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) BLOC1S3 PF15753.5 PRP73379.1 - 0.033 14.3 0.3 0.066 13.3 0.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 MCPsignal PF00015.21 PRP73379.1 - 0.045 13.6 4.7 0.16 11.7 4.5 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain YfdX PF10938.8 PRP73379.1 - 0.049 13.6 0.3 0.19 11.6 0.1 2.0 2 0 0 2 2 2 0 YfdX protein DUF3584 PF12128.8 PRP73379.1 - 0.061 10.8 0.0 0.077 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec8_exocyst PF04048.14 PRP73379.1 - 0.09 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc7 PF08317.11 PRP73379.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 PRP73379.1 - 0.22 11.6 0.9 2.1 8.4 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 PRP73379.1 - 0.23 11.7 1.6 0.71 10.2 0.0 2.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) F-box-like PF12937.7 PRP73380.1 - 1.3e-08 34.6 2.1 4.6e-08 32.8 2.1 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 PRP73380.1 - 1.3e-06 28.7 11.1 0.00042 20.6 0.0 6.2 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP73380.1 - 0.00039 20.3 4.6 0.61 10.3 0.0 5.3 4 0 0 4 4 4 1 Leucine Rich repeat F-box PF00646.33 PRP73380.1 - 0.00094 19.0 3.2 0.00094 19.0 3.2 2.8 3 0 0 3 3 3 1 F-box domain GST_C_6 PF17171.4 PRP73380.1 - 0.03 14.1 0.4 9.3 6.1 0.0 3.9 3 1 1 4 4 4 0 Glutathione S-transferase, C-terminal domain Calmodulin_bind PF07887.11 PRP73380.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Calmodulin binding protein-like HRDC PF00570.23 PRP73380.1 - 0.16 12.0 0.0 29 4.7 0.0 3.7 3 1 1 4 4 4 0 HRDC domain NUDIX PF00293.28 PRP73381.1 - 2.8e-11 43.6 0.0 4.1e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Rep_fac-A_3 PF08661.11 PRP73382.1 - 3.4e-14 53.1 0.1 3.7e-14 52.9 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ldh_1_N PF00056.23 PRP73383.1 - 1.1e-33 116.3 0.1 1.8e-33 115.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PRP73383.1 - 1.1e-33 116.5 0.0 2.4e-33 115.4 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain TPP_enzyme_M PF00205.22 PRP73383.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain PEPCK_ATP PF01293.20 PRP73384.1 - 0.0077 15.0 0.1 0.0089 14.8 0.1 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase cpYpsA PF12694.7 PRP73384.1 - 0.083 12.7 0.3 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family Cytidylate_kin PF02224.18 PRP73385.1 - 0.0088 15.8 1.5 0.23 11.2 0.3 2.1 1 1 1 2 2 2 1 Cytidylate kinase F_actin_bind PF08919.10 PRP73385.1 - 0.038 14.1 2.2 0.13 12.4 1.7 2.2 2 1 0 2 2 2 0 F-actin binding DUF2630 PF10944.8 PRP73385.1 - 0.083 13.4 0.4 0.083 13.4 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2630) SYF2 PF08231.12 PRP73385.1 - 0.23 11.9 5.2 0.31 11.4 5.2 1.1 1 0 0 1 1 1 0 SYF2 splicing factor FUSC PF04632.12 PRP73385.1 - 0.42 9.1 2.1 0.55 8.7 2.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FAD_binding_4 PF01565.23 PRP73387.1 - 7.9e-25 87.2 3.4 7.9e-25 87.2 3.4 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 PRP73387.1 - 1.2e-13 50.9 0.5 1.2e-13 50.9 0.5 2.6 2 0 0 2 2 2 1 Berberine and berberine like RdRP PF05183.12 PRP73388.1 - 1.3e-111 374.1 0.0 1.9e-111 373.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase R3H PF01424.22 PRP73389.1 - 2e-08 34.1 0.0 4.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain MYO10_CC PF16735.5 PRP73389.1 - 5.9 7.1 6.4 14 5.8 1.1 3.3 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain Homeodomain PF00046.29 PRP73391.1 - 3.7e-14 52.3 2.3 5.9e-14 51.7 2.3 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP73391.1 - 2.4e-05 24.1 1.5 4.4e-05 23.3 1.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain Methyltransf_11 PF08241.12 PRP73392.1 - 1.7e-20 73.5 0.0 3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP73392.1 - 3.8e-18 66.0 0.0 6.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP73392.1 - 7.4e-17 61.5 0.0 1e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP73392.1 - 2.3e-16 60.1 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP73392.1 - 1e-14 55.1 0.0 1.7e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP73392.1 - 2.1e-11 43.6 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 PRP73392.1 - 2.3e-09 36.9 0.0 7.3e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.11 PRP73392.1 - 2e-05 24.3 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 PRP73392.1 - 2e-05 24.0 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 PRP73392.1 - 0.00027 21.2 0.0 0.00084 19.7 0.0 1.7 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase TPMT PF05724.11 PRP73392.1 - 0.0031 17.2 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_PK PF05891.12 PRP73392.1 - 0.0033 17.0 0.0 0.0045 16.5 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 PRP73392.1 - 0.0089 16.0 0.1 0.019 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 PRP73392.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 PRP73392.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrpR_N PF06506.11 PRP73392.1 - 0.026 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Propionate catabolism activator MTS PF05175.14 PRP73392.1 - 0.027 14.0 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 PRP73392.1 - 0.032 13.6 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 PRP73392.1 - 0.093 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 PRP73392.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UDPG_MGDP_dh_N PF03721.14 PRP73392.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pam16 PF03656.13 PRP73393.1 - 6.7e-06 26.1 0.0 1.1e-05 25.5 0.0 1.3 1 1 0 1 1 1 1 Pam16 Arm_2 PF04826.13 PRP73394.1 - 0.03 13.8 1.0 0.64 9.4 1.4 2.2 1 1 1 2 2 2 0 Armadillo-like Tubulin PF00091.25 PRP73395.1 - 8.9e-70 234.9 0.0 1.6e-69 234.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PRP73395.1 - 4e-41 140.1 0.0 6.4e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PRP73395.1 - 4.4e-05 23.8 0.1 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PRP73395.1 - 0.0033 16.7 0.1 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 PRP73395.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Tubulin PF00091.25 PRP73396.1 - 1.8e-68 230.6 0.0 2.5e-68 230.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PRP73396.1 - 5.8e-52 175.1 0.0 9.5e-52 174.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PRP73396.1 - 0.0011 18.6 0.0 0.0031 17.2 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain Macoilin PF09726.9 PRP73397.1 - 0.011 14.4 42.1 0.047 12.3 42.1 1.8 1 1 0 1 1 1 0 Macoilin family Meckelin PF09773.9 PRP73397.1 - 0.049 11.7 7.0 0.079 11.0 7.0 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF812 PF05667.11 PRP73397.1 - 0.15 10.9 36.5 0.32 9.8 36.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TMP_2 PF06791.13 PRP73397.1 - 0.16 11.6 4.5 0.23 11.1 4.5 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF4407 PF14362.6 PRP73397.1 - 1.6 8.0 32.1 3.4e+02 0.4 32.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rotamase PF00639.21 PRP73397.1 - 2.5 9.1 9.1 0.74 10.8 5.0 2.4 2 1 0 2 2 2 0 PPIC-type PPIASE domain YkyA PF10368.9 PRP73397.1 - 3.3 7.4 29.8 0.15 11.7 17.2 2.5 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein JIP_LZII PF16471.5 PRP73397.1 - 5.6 7.2 29.3 7.7 6.8 4.1 4.7 4 1 0 4 4 4 0 JNK-interacting protein leucine zipper II Golgin_A5 PF09787.9 PRP73397.1 - 7.2 6.0 43.7 0.72 9.3 21.8 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 zf-CCCH_4 PF18044.1 PRP73398.1 - 0.00072 19.3 5.4 0.0016 18.2 5.4 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 PRP73398.1 - 0.0042 17.0 3.8 0.01 15.8 3.8 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP73398.1 - 0.01 15.9 6.7 0.021 14.9 6.7 1.6 1 0 0 1 1 1 0 Zinc finger domain Torus PF16131.5 PRP73398.1 - 0.013 16.2 1.6 0.042 14.6 1.6 1.9 1 0 0 1 1 1 0 Torus domain U3_assoc_6 PF08640.11 PRP73399.1 - 2.3e-10 40.4 3.3 2.3e-10 40.4 3.3 3.3 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 PRP73399.1 - 9.9e-06 26.0 7.9 0.0045 17.7 0.9 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 PRP73399.1 - 0.00011 21.5 0.2 0.0026 17.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat NRDE-2 PF08424.10 PRP73399.1 - 0.00016 20.9 3.2 0.014 14.5 0.2 3.3 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 PRP73399.1 - 0.00028 21.3 3.1 0.023 15.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP73399.1 - 0.0041 17.2 3.5 1.9 8.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP73399.1 - 0.0062 16.6 4.9 8.3 6.8 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PRP73399.1 - 0.027 14.5 0.6 0.29 11.1 0.0 3.0 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 Plk4_PB2 PF18409.1 PRP73399.1 - 0.098 13.3 0.1 13 6.5 0.1 2.6 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 HRG PF16954.5 PRP73402.1 - 0.25 11.7 3.3 0.91 10.0 0.2 2.7 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Raptor_N PF14538.6 PRP73403.1 - 1.6e-66 222.8 0.0 3.2e-66 221.8 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 PRP73403.1 - 1.1e-10 40.8 3.4 0.013 15.7 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 PRP73403.1 - 1.7e-10 41.1 0.1 0.00016 22.0 0.0 3.5 3 1 2 5 5 5 3 HEAT repeats WD40 PF00400.32 PRP73403.1 - 3.8e-10 40.2 11.8 0.25 12.3 0.0 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Cnd1 PF12717.7 PRP73403.1 - 9.9e-07 28.9 0.0 0.002 18.2 0.0 3.6 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 PRP73403.1 - 0.0015 18.8 0.0 28 5.1 0.0 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 PRP73403.1 - 0.0078 16.7 0.6 1 9.9 0.0 3.3 2 1 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.20 PRP73403.1 - 0.028 13.0 0.0 0.27 9.8 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Atx10homo_assoc PF09759.9 PRP73403.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Cohesin_HEAT PF12765.7 PRP73403.1 - 0.32 11.3 3.1 28 5.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion 3HCDH_N PF02737.18 PRP73404.1 - 3.1e-40 138.0 1.6 2.5e-39 135.0 1.6 2.1 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 PRP73404.1 - 1.9e-16 60.5 0.0 7.6e-16 58.5 0.0 2.0 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 PRP73404.1 - 0.00012 22.0 0.1 0.00029 20.8 0.1 1.6 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 PRP73404.1 - 0.00015 22.0 0.1 0.00063 19.9 0.1 2.0 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 PRP73404.1 - 0.0039 16.8 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 PRP73404.1 - 0.0056 16.1 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 PRP73404.1 - 0.012 14.8 0.1 0.061 12.6 0.2 2.0 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 PRP73404.1 - 0.057 12.8 0.1 0.078 12.4 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.6 PRP73404.1 - 0.068 13.6 0.2 1.2 9.6 0.1 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 PRP73404.1 - 0.071 13.7 0.1 0.48 11.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PRP73404.1 - 0.073 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DNA_primase_S PF01896.19 PRP73405.1 - 4.9e-56 189.6 0.6 7.4e-56 189.0 0.6 1.3 1 0 0 1 1 1 1 DNA primase small subunit DUF3018 PF11455.8 PRP73405.1 - 0.021 14.7 0.2 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) DUF1769 PF08588.10 PRP73406.1 - 0.06 13.5 0.1 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) START PF01852.19 PRP73407.1 - 0.0064 15.9 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 START domain FtsJ PF01728.19 PRP73408.1 - 1.5e-21 77.3 0.0 4.1e-17 62.9 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 PRP73408.1 - 0.014 13.5 0.1 0.024 12.7 0.1 1.3 1 0 0 1 1 1 0 Virus-capping methyltransferase Proteasome PF00227.26 PRP73409.1 - 8.6e-38 129.7 0.0 1.5e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit HA PF03457.14 PRP73409.1 - 1.7e-14 53.9 1.2 8.2e-05 22.9 0.1 3.6 3 0 0 3 3 3 3 Helicase associated domain Guanylate_cyc PF00211.20 PRP73410.1 - 1.4e-59 200.8 3.0 3.7e-34 117.9 0.3 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Ribosomal_L12_N PF16320.5 PRP73410.1 - 0.006 16.3 0.0 5.2 6.9 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein L7/L12 dimerisation domain Baculo_gp64 PF03273.13 PRP73410.1 - 0.027 13.3 0.1 4.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Baculovirus gp64 envelope glycoprotein family DUF4123 PF13503.6 PRP73410.1 - 0.15 12.5 0.3 28 5.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) BRCT_2 PF16589.5 PRP73410.1 - 0.16 12.4 0.0 27 5.3 0.0 2.6 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain TPR_2 PF07719.17 PRP73410.1 - 0.2 11.9 1.3 6.8 7.1 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat YoqO PF14037.6 PRP73410.1 - 0.3 11.6 7.2 0.27 11.8 0.9 3.3 2 0 0 2 2 2 0 YoqO-like protein DUF5453 PF17534.2 PRP73410.1 - 0.53 10.2 4.8 3.2 7.7 0.4 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5453) DUF2873 PF11395.8 PRP73410.1 - 2.3 8.1 4.5 11 5.9 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2873) Sigma_reg_N PF13800.6 PRP73410.1 - 7.3 7.0 18.9 3.2 8.1 0.4 4.2 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Cyt-b5 PF00173.28 PRP73412.1 - 7.5e-13 48.4 0.0 8.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LEA_4 PF02987.16 PRP73413.1 - 0.0046 17.0 3.4 0.0046 17.0 3.4 4.2 4 1 1 5 5 5 2 Late embryogenesis abundant protein Thioredoxin PF00085.20 PRP73415.1 - 1.1e-28 99.2 0.1 1.3e-28 99.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 PRP73415.1 - 4.3e-06 27.0 0.0 6.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 PRP73415.1 - 8.8e-06 24.9 0.0 9.9e-06 24.7 0.0 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin_2 PF13098.6 PRP73415.1 - 1.5e-05 25.4 0.1 0.00015 22.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 PRP73415.1 - 2.8e-05 24.0 0.1 3.1e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PRP73415.1 - 0.0014 18.4 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PRP73415.1 - 0.0014 18.1 0.1 0.0015 18.0 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 PRP73415.1 - 0.0015 18.2 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin DIM1 PF02966.16 PRP73415.1 - 0.0043 16.8 0.0 0.0053 16.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.11 PRP73415.1 - 0.0048 16.8 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 PRP73415.1 - 0.018 15.2 0.1 0.031 14.5 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 PRP73415.1 - 0.023 14.9 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin DUF810 PF05664.11 PRP73416.1 - 2.8e-21 75.8 0.0 8e-20 71.0 0.0 2.1 1 1 0 1 1 1 1 Plant family of unknown function (DUF810) RNase_T PF00929.24 PRP73417.1 - 3.8e-21 76.3 0.0 5.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 PRP73417.1 - 0.046 13.7 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like RRF PF01765.19 PRP73417.1 - 0.12 12.3 0.1 1.5 8.8 0.1 2.1 2 0 0 2 2 2 0 Ribosome recycling factor Peptidase_C50 PF03568.17 PRP73418.1 - 4.1e-81 273.1 0.0 4.1e-81 273.1 0.0 3.2 3 0 0 3 3 3 1 Peptidase family C50 TPR_8 PF13181.6 PRP73418.1 - 1.1e-07 31.5 1.3 0.58 10.5 0.1 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP73418.1 - 5.8e-07 29.7 14.1 0.01 16.1 0.3 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP73418.1 - 4.3e-05 23.3 8.0 0.53 10.5 0.3 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP73418.1 - 0.0084 16.7 1.3 28 5.6 0.0 4.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP73418.1 - 0.009 16.8 4.8 58 4.9 0.1 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat BID PF06393.11 PRP73418.1 - 0.019 14.5 2.6 0.49 9.9 0.0 2.6 2 0 0 2 2 2 0 BH3 interacting domain (BID) TPR_19 PF14559.6 PRP73418.1 - 0.022 15.2 3.7 0.95 10.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP73418.1 - 0.041 13.7 3.6 4.9 7.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP73418.1 - 0.058 13.4 8.5 39 4.6 0.5 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP73418.1 - 0.062 13.2 0.1 0.062 13.2 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 PRP73418.1 - 0.11 12.5 0.2 0.51 10.4 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TetR_C_1 PF02909.17 PRP73419.1 - 0.012 15.4 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Suppressor_P21 PF11479.8 PRP73419.1 - 0.018 15.2 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain Pkinase_Tyr PF07714.17 PRP73420.1 - 8.3e-59 199.0 0.0 3.9e-58 196.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP73420.1 - 1.8e-42 145.5 0.0 4.6e-42 144.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 PRP73420.1 - 8.6e-25 86.4 65.8 0.00013 22.3 3.8 11.4 4 2 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP73420.1 - 5.8e-22 77.2 74.9 5.7e-05 22.8 1.4 10.3 2 2 10 13 13 13 12 Leucine rich repeat Kdo PF06293.14 PRP73420.1 - 0.0027 17.1 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 PRP73420.1 - 0.0042 17.0 57.7 1.7 8.9 0.1 14.2 15 0 0 15 15 15 2 Leucine Rich repeat MMM1 PF10296.9 PRP73420.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 TMEM154 PF15102.6 PRP73420.1 - 0.024 14.5 0.1 0.024 14.5 0.1 2.0 2 0 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.16 PRP73420.1 - 0.038 12.8 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4083 PF13314.6 PRP73420.1 - 0.04 13.9 0.2 0.095 12.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) LRR_9 PF14580.6 PRP73420.1 - 0.046 13.2 16.4 2.3 7.7 0.2 4.4 2 1 3 5 5 5 0 Leucine-rich repeat EphA2_TM PF14575.6 PRP73420.1 - 0.11 13.3 0.1 0.25 12.3 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Colipase-like PF15083.6 PRP73423.1 - 0.075 13.2 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Colipase-like rve PF00665.26 PRP73424.1 - 3.2e-20 72.5 0.0 5.3e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain 2OG-FeII_Oxy_2 PF13532.6 PRP73425.1 - 0.00098 19.4 0.0 0.35 11.0 0.0 2.3 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily DUF2070 PF09843.9 PRP73426.1 - 1.1 7.4 14.2 0.85 7.8 11.8 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) LEAP-2 PF07359.11 PRP73427.1 - 0.029 14.2 0.2 0.058 13.2 0.2 1.5 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Kdo PF06293.14 PRP73428.1 - 1.7e-08 34.1 0.0 4.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PRP73428.1 - 1.1e-07 31.5 0.0 1.1e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 PRP73428.1 - 7.8e-06 26.0 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP73428.1 - 1.9e-05 24.4 1.6 3.3e-05 23.6 0.0 2.1 3 0 0 3 3 3 1 RIO1 family WaaY PF06176.11 PRP73428.1 - 4.1e-05 23.3 0.6 8.6e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 PRP73428.1 - 0.00038 20.1 2.3 0.001 18.7 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 PRP73428.1 - 0.0048 16.2 0.0 0.0097 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase eIF-4B PF06273.11 PRP73428.1 - 0.72 8.9 8.2 1 8.3 8.2 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Dynamin_M PF01031.20 PRP73429.1 - 0.039 13.2 0.2 0.05 12.8 0.2 1.1 1 0 0 1 1 1 0 Dynamin central region EF-hand_14 PF17959.1 PRP73429.1 - 0.21 11.9 1.1 1.3 9.4 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain DoxA PF07680.11 PRP73430.1 - 0.0099 15.8 0.4 2.6 7.9 0.1 2.3 2 1 0 2 2 2 2 TQO small subunit DoxA VitD-bind_III PF09164.10 PRP73430.1 - 0.021 14.8 4.7 5.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Vitamin D binding protein, domain III DUF2161 PF09929.9 PRP73430.1 - 0.036 14.2 0.1 3 8.0 0.0 2.2 1 1 1 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) PapB PF03333.13 PRP73430.1 - 0.061 13.4 0.5 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Adhesin biosynthesis transcription regulatory protein AF2331-like PF14556.6 PRP73430.1 - 0.1 13.2 0.0 15 6.2 0.0 2.6 3 0 0 3 3 3 0 AF2331-like Spc110_C PF18520.1 PRP73430.1 - 0.18 11.5 0.8 19 5.0 0.1 2.6 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain HTH_Mga PF08280.11 PRP73430.1 - 2.1 8.4 10.8 1.1 9.3 1.6 2.9 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain rve PF00665.26 PRP73431.1 - 1.8e-22 79.8 0.0 2.9e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain CNOT1_HEAT PF16418.5 PRP73432.1 - 0.0021 18.2 0.2 4.6 7.3 0.0 3.2 3 0 0 3 3 3 2 CCR4-NOT transcription complex subunit 1 HEAT repeat Actin PF00022.19 PRP73433.1 - 3.7e-29 101.5 0.0 4.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Actin SASA PF03629.18 PRP73434.1 - 9.6e-12 45.0 0.0 1.5e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase DUF3287 PF11690.8 PRP73435.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) FLYWCH_u PF16662.5 PRP73437.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 Rota_NS26 PF01525.16 PRP73438.1 - 0.088 12.8 0.0 0.091 12.8 0.0 1.0 1 0 0 1 1 1 0 Rotavirus NS26 Popeye PF04831.13 PRP73439.1 - 0.21 11.7 1.9 0.35 11.0 1.9 1.3 1 0 0 1 1 1 0 Popeye protein conserved region AKNA PF12443.8 PRP73442.1 - 0.0091 16.6 1.6 0.0091 16.6 1.6 2.0 2 0 0 2 2 2 1 AT-hook-containing transcription factor Seryl_tRNA_N PF02403.22 PRP73442.1 - 0.93 9.8 8.4 0.18 12.0 1.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RCSD PF05177.12 PRP73442.1 - 6.2 7.8 12.2 5.5 8.0 6.4 2.3 1 1 1 2 2 2 0 RCSD region RVT_1 PF00078.27 PRP73443.1 - 5.5e-37 127.4 1.3 1.9e-24 86.5 0.6 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 PRP73443.1 - 1.1e-35 122.1 0.0 2.4e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP73443.1 - 1.1e-30 105.7 0.0 2.2e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP73443.1 - 1.1e-21 76.6 0.6 2.9e-21 75.3 0.6 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP73443.1 - 5.4e-11 42.7 0.1 2.9e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain MFS_1 PF07690.16 PRP73443.1 - 2.3e-09 36.6 8.9 3.4e-09 36.1 8.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Chromo PF00385.24 PRP73443.1 - 1.5e-08 34.4 0.0 4.9e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 PRP73443.1 - 3.1e-05 24.4 0.0 6.9e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.10 PRP73443.1 - 6.7e-05 23.0 0.2 0.00059 20.0 0.1 2.7 3 0 0 3 3 3 1 H2C2 zinc finger Asp_protease_2 PF13650.6 PRP73443.1 - 0.00024 21.7 0.0 0.00056 20.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Nuc_H_symport PF03825.16 PRP73443.1 - 0.0052 15.8 1.6 0.0081 15.2 1.6 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.7 PRP73443.1 - 0.043 12.7 0.5 0.075 11.9 0.5 1.3 1 0 0 1 1 1 0 MFS_1 like family Sugar_tr PF00083.24 PRP73443.1 - 0.078 11.8 3.4 0.12 11.2 3.4 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter His_biosynth PF00977.21 PRP73443.1 - 0.14 11.6 0.0 22 4.4 0.0 2.4 2 0 0 2 2 2 0 Histidine biosynthesis protein MFS_2 PF13347.6 PRP73443.1 - 0.22 10.0 5.0 0.35 9.4 5.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Pkinase_Tyr PF07714.17 PRP73444.1 - 4.7e-46 157.2 0.0 4.1e-44 150.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP73444.1 - 2.5e-41 139.2 61.0 3.1e-09 36.5 0.3 9.7 9 0 0 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 PRP73444.1 - 2.7e-35 119.8 59.8 1.6e-05 25.2 3.5 11.6 8 2 3 13 13 12 11 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP73444.1 - 7.3e-31 107.5 0.0 5.8e-30 104.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 PRP73444.1 - 8.7e-14 50.3 51.0 0.21 11.8 0.3 15.8 17 0 0 17 17 17 6 Leucine Rich repeat LRR_1 PF00560.33 PRP73444.1 - 2.2e-09 36.6 48.6 0.28 11.9 0.1 17.0 17 1 1 18 18 18 1 Leucine Rich Repeat Amnionless PF14828.6 PRP73444.1 - 0.0078 15.1 0.2 0.012 14.4 0.2 1.2 1 0 0 1 1 1 1 Amnionless DAP10 PF07213.11 PRP73444.1 - 0.16 11.9 0.5 0.52 10.3 0.5 1.8 1 0 0 1 1 1 0 DAP10 membrane protein DUF347 PF03988.12 PRP73444.1 - 0.18 12.0 0.7 0.35 11.1 0.7 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) VSP PF03302.13 PRP73444.1 - 0.36 9.6 1.5 0.6 8.9 1.5 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Insulin_TMD PF17870.1 PRP73444.1 - 0.83 9.8 2.8 2 8.5 2.8 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRR_9 PF14580.6 PRP73444.1 - 2.5 7.6 9.3 0.72 9.3 0.3 4.0 4 1 0 4 4 4 0 Leucine-rich repeat DUF4384 PF14326.6 PRP73448.1 - 0.036 14.2 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) DUF3456 PF11938.8 PRP73448.1 - 0.053 14.0 0.1 3.8 8.0 0.0 2.2 1 1 1 2 2 2 0 TLR4 regulator and MIR-interacting MSAP Carbam_trans_C PF16861.5 PRP73448.1 - 0.069 12.7 0.3 6.8 6.3 0.1 2.2 1 1 0 2 2 2 0 Carbamoyltransferase C-terminus RT_RNaseH PF17917.1 PRP73449.1 - 1.5e-33 115.2 0.3 5.4e-33 113.4 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP73449.1 - 4.7e-32 110.0 0.0 9.8e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP73449.1 - 5.1e-24 85.0 1.4 4.1e-19 69.0 0.3 3.3 2 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.6 PRP73449.1 - 0.00027 21.4 0.0 0.00067 20.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PRP73449.1 - 0.00049 20.7 0.0 0.0016 19.0 0.0 2.0 1 0 0 1 1 1 1 Aspartyl protease DUF5344 PF17279.2 PRP73449.1 - 0.042 14.4 4.9 11 6.7 0.0 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5344) Baculo_PEP_C PF04513.12 PRP73449.1 - 0.68 10.0 4.8 6.1 6.9 0.1 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4124 PF13511.6 PRP73449.1 - 1 9.7 3.2 11 6.5 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4124) RNA_pol_Rpb1_3 PF04983.18 PRP73450.1 - 7.8e-13 48.7 0.1 1.4e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 TatD_DNase PF01026.21 PRP73450.1 - 1.6e-07 31.0 0.0 1.8e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase RNA_pol_Rpb1_5 PF04998.17 PRP73451.1 - 8.5e-17 61.5 0.0 1.2e-05 24.9 0.6 4.4 2 2 1 3 3 3 3 RNA polymerase Rpb1, domain 5 RhoGEF PF00621.20 PRP73451.1 - 7.9e-09 36.0 0.7 5.3e-08 33.3 0.0 2.5 2 0 0 2 2 2 1 RhoGEF domain RNA_pol_Rpb1_6 PF04992.14 PRP73451.1 - 3.7e-07 30.1 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 6 DUF1996 PF09362.10 PRP73452.1 - 3.8e-08 33.6 0.2 8.5e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) PAS_2 PF08446.11 PRP73453.1 - 0.087 13.5 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 PAS fold LRR_6 PF13516.6 PRP73455.1 - 0.049 13.7 2.8 0.099 12.7 0.0 3.1 5 0 0 5 5 5 0 Leucine Rich repeat Imm41 PF15592.6 PRP73455.1 - 0.053 13.9 0.1 0.14 12.5 0.1 1.7 2 0 0 2 2 2 0 Immunity protein 41 FragX_IP PF05994.11 PRP73456.1 - 7.6e-80 269.1 0.1 9.8e-80 268.7 0.1 1.1 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 PRP73456.1 - 2.3e-10 40.3 1.0 4.9e-10 39.1 1.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Flexi_CP PF00286.20 PRP73456.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Viral coat protein DUF1706 PF08020.11 PRP73456.1 - 0.019 14.9 0.1 0.071 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) Y_phosphatase PF00102.27 PRP73463.1 - 9.6e-62 208.6 8.9 6.8e-32 110.9 0.4 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP73463.1 - 1.4e-05 25.1 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PRP73463.1 - 0.00049 19.9 3.2 0.0012 18.7 0.3 3.0 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PRP73463.1 - 0.021 15.0 0.4 0.14 12.3 0.0 2.4 2 1 0 2 2 2 0 Inositol hexakisphosphate DUF3342 PF11822.8 PRP73463.1 - 0.098 12.9 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) zf-C3HC PF07967.13 PRP73466.1 - 9e-29 100.2 1.6 6e-22 78.1 0.0 3.6 3 0 0 3 3 3 3 C3HC zinc finger-like Rsm1 PF08600.10 PRP73466.1 - 3.6e-08 33.5 14.6 0.023 14.9 0.1 5.1 4 3 2 6 6 6 3 Rsm1-like DM PF00751.18 PRP73466.1 - 0.19 11.6 3.1 9.7 6.2 0.2 2.7 2 0 0 2 2 2 0 DM DNA binding domain Pet127 PF08634.10 PRP73467.1 - 1.3e-80 270.8 3.2 1.7e-80 270.4 3.2 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 SpoU_methylase PF00588.19 PRP73468.1 - 0.00031 20.9 0.0 1.3 9.2 0.0 2.4 1 1 0 2 2 2 2 SpoU rRNA Methylase family TcdA_TcdB_pore PF12920.7 PRP73468.1 - 0.65 8.2 3.7 0.9 7.7 3.7 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain GRAM PF02893.20 PRP73469.1 - 0.0029 17.5 0.1 0.0048 16.8 0.1 1.3 1 0 0 1 1 1 1 GRAM domain DUF608 PF04685.13 PRP73470.1 - 5.5e-23 81.7 0.5 7.8e-23 81.2 0.5 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region SNAP PF14938.6 PRP73472.1 - 3.2e-16 59.6 18.2 2.8e-15 56.5 18.0 2.1 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 PRP73472.1 - 2.8e-05 24.3 8.0 0.043 14.1 2.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP73472.1 - 0.14 12.3 9.8 77 3.8 0.3 5.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 PRP73472.1 - 0.2 12.4 9.9 7.7 7.4 2.3 5.1 4 3 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP73472.1 - 1.5 8.8 8.6 30 4.7 4.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat DHBP_synthase PF00926.19 PRP73473.1 - 7.8e-81 270.2 0.0 1.3e-80 269.5 0.0 1.4 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 PRP73473.1 - 2.7e-47 160.4 0.0 5.1e-47 159.5 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II CbiG_mid PF11761.8 PRP73473.1 - 0.034 14.3 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis central region zf-CpG_bind_C PF12269.8 PRP73474.1 - 1.9e-13 50.8 17.4 3.1e-10 40.2 2.7 2.9 2 1 1 3 3 3 2 CpG binding protein zinc finger C terminal domain PHD PF00628.29 PRP73474.1 - 7.5e-13 48.2 7.9 7.5e-13 48.2 7.9 3.9 3 1 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 PRP73474.1 - 0.00024 20.6 2.0 0.00024 20.6 2.0 3.3 3 0 0 3 3 3 1 PHD-finger DUF3967 PF13152.6 PRP73474.1 - 0.0038 17.0 0.4 0.011 15.4 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3967) PHD_3 PF13922.6 PRP73474.1 - 0.089 13.2 0.4 0.089 13.2 0.4 3.0 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx RabGAP-TBC PF00566.18 PRP73475.1 - 6e-54 182.9 0.1 6e-54 182.9 0.1 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 PRP73475.1 - 7.3e-24 83.9 4.4 3.2e-13 49.5 0.2 3.0 2 1 0 2 2 2 2 GRAM domain EF-hand_7 PF13499.6 PRP73475.1 - 3e-08 34.0 7.3 5.6e-05 23.5 0.3 3.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP73475.1 - 1.9e-05 23.8 2.1 0.026 14.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PRP73475.1 - 9.8e-05 22.0 0.9 0.014 15.3 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 PRP73475.1 - 0.0047 16.8 1.0 0.11 12.3 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP73475.1 - 0.016 14.7 0.7 0.074 12.6 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 PRP73475.1 - 0.46 10.5 3.2 35 4.4 0.1 4.1 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand Syja_N PF02383.18 PRP73476.1 - 4.8e-72 243.0 0.1 1e-71 241.9 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain SET PF00856.28 PRP73476.1 - 2.2e-13 51.0 0.1 5.9e-13 49.6 0.1 1.7 2 0 0 2 2 2 1 SET domain Pre-SET PF05033.16 PRP73476.1 - 5.3e-09 36.7 6.4 5.3e-09 36.7 6.4 2.4 2 0 0 2 2 2 1 Pre-SET motif DUF1604 PF07713.13 PRP73477.1 - 6e-35 118.9 3.1 6e-35 118.9 3.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 PRP73477.1 - 2.8e-05 23.9 0.4 7.7e-05 22.5 0.4 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PRP73477.1 - 0.022 14.8 0.1 0.022 14.8 0.1 3.6 3 0 0 3 3 3 0 G-patch domain ETRAMP PF09716.10 PRP73477.1 - 8.3 6.6 5.7 5.3 7.2 1.9 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RasGAP PF00616.19 PRP73479.1 - 6.9e-12 45.5 0.4 1.3e-06 28.2 0.4 4.0 3 1 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase Atg14 PF10186.9 PRP73479.1 - 6.7 5.7 19.0 26 3.8 19.0 2.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 PRP73480.1 - 2.9e-52 177.7 0.0 5e-52 176.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73480.1 - 2.2e-26 92.7 0.0 3.5e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP73480.1 - 5.3e-06 25.5 0.1 9.4e-06 24.6 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP73480.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP73480.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PRP73480.1 - 0.014 14.5 0.4 0.023 13.8 0.4 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 JmjC PF02373.22 PRP73480.1 - 0.042 14.3 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase Kdo PF06293.14 PRP73480.1 - 0.081 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phosphonate-bd PF12974.7 PRP73481.1 - 5.1e-06 26.3 1.0 2.8e-05 23.9 0.2 2.3 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 PRP73481.1 - 1.4e-05 25.2 0.1 3.1e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 NMT1/THI5 like FliG_M PF14841.6 PRP73481.1 - 0.11 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 FliG middle domain CBM49 PF09478.10 PRP73481.1 - 0.14 12.5 0.5 0.62 10.4 0.2 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain CBM49 EGF_2 PF07974.13 PRP73482.1 - 0.11 12.9 5.8 0.23 11.9 5.8 1.5 1 0 0 1 1 1 0 EGF-like domain FA_desaturase PF00487.24 PRP73482.1 - 0.69 9.7 8.5 1.6 8.5 1.9 2.3 2 0 0 2 2 2 0 Fatty acid desaturase EB PF01683.18 PRP73482.1 - 1.2 9.4 5.2 0.28 11.5 1.8 1.6 2 0 0 2 2 2 0 EB module EGF PF00008.27 PRP73482.1 - 3 8.2 7.3 5.9 7.3 7.3 1.5 1 0 0 1 1 1 0 EGF-like domain PH PF00169.29 PRP73483.1 - 2.4e-19 69.8 0.3 5.1e-19 68.7 0.1 1.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 PRP73483.1 - 8.9e-08 32.5 1.0 2.5e-07 31.0 1.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PRP73483.1 - 8.4e-06 26.0 0.1 1.8e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PRP73483.1 - 0.00016 22.1 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 PRP73483.1 - 0.0015 18.6 0.1 0.0065 16.5 0.1 1.8 1 1 0 1 1 1 1 PH domain PH_12 PF16457.5 PRP73483.1 - 0.16 12.5 0.0 0.6 10.6 0.0 1.8 1 1 1 2 2 2 0 Pleckstrin homology domain LpqV PF17301.2 PRP73483.1 - 0.17 12.1 0.3 0.55 10.5 0.1 1.8 2 0 0 2 2 2 0 Putative lipoprotein LpqV CTP_transf_like PF01467.26 PRP73484.1 - 1.3e-45 155.1 0.0 2.2e-29 102.5 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 PRP73484.1 - 0.00018 21.4 0.7 1 9.2 0.0 3.1 3 0 0 3 3 3 2 FAD synthetase ScdA_N PF04405.14 PRP73484.1 - 0.0025 17.4 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown function (DUF542) CoA_binding_3 PF13727.6 PRP73484.1 - 0.0059 16.6 0.0 0.26 11.3 0.0 2.2 2 0 0 2 2 2 1 CoA-binding domain Oxidored_molyb PF00174.19 PRP73484.1 - 0.12 12.0 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase molybdopterin binding domain F420_oxidored PF03807.17 PRP73485.1 - 6.8e-17 61.8 0.2 1.5e-16 60.8 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent P5CR_dimer PF14748.6 PRP73485.1 - 5.1e-14 52.4 0.5 1.1e-13 51.3 0.1 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation NAD_binding_2 PF03446.15 PRP73485.1 - 0.018 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 PRP73485.1 - 0.022 14.7 2.3 0.045 13.7 0.5 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.17 PRP73485.1 - 0.057 12.4 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase ApbA PF02558.16 PRP73485.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 PRP73485.1 - 0.14 12.2 0.3 0.35 10.9 0.3 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PHD_like PF12910.7 PRP73487.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system SRP_TPR_like PF17004.5 PRP73489.1 - 3e-20 72.4 11.3 1.9e-18 66.6 1.1 4.1 3 1 0 4 4 4 2 Putative TPR-like repeat TPR_19 PF14559.6 PRP73489.1 - 2.7e-15 56.6 12.5 8.6e-06 26.2 0.0 7.4 4 3 2 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP73489.1 - 5.1e-14 51.8 1.6 0.31 12.0 0.0 9.8 5 4 6 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP73489.1 - 1.9e-11 43.2 4.2 2.1 8.7 0.0 9.5 10 0 0 10 10 10 1 Tetratricopeptide repeat SRP72 PF08492.12 PRP73489.1 - 4.7e-11 43.0 9.5 4.7e-11 43.0 9.5 2.1 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_6 PF13174.6 PRP73489.1 - 1.5e-10 41.0 4.9 0.094 13.4 0.0 6.9 8 0 0 8 8 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP73489.1 - 5.2e-09 36.2 8.1 0.043 14.1 0.1 6.0 4 3 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PRP73489.1 - 5.7e-09 36.5 0.4 1.6 9.4 0.0 6.8 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP73489.1 - 1.3e-08 34.4 1.2 12 6.4 0.0 8.0 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP73489.1 - 3e-07 30.0 1.9 1 9.3 0.0 7.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP73489.1 - 1e-06 28.8 1.5 1.2 9.4 0.0 5.0 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP73489.1 - 1.2e-06 28.1 2.1 5.1 7.3 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP73489.1 - 1.7e-06 28.2 6.7 0.19 12.1 0.0 6.2 4 2 3 7 7 7 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PRP73489.1 - 8.2e-06 25.5 0.8 0.0015 18.1 0.0 4.3 3 2 2 6 6 6 1 Bacterial type III secretion protein (HrpB1_HrpK) DUF4322 PF14210.6 PRP73489.1 - 0.18 11.7 0.9 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4322) Clathrin_H_link PF13838.6 PRP73489.1 - 0.4 10.6 3.1 38 4.3 0.1 4.4 5 0 0 5 5 5 0 Clathrin-H-link TPR_17 PF13431.6 PRP73489.1 - 1.2 9.7 6.9 18 6.0 0.1 5.6 8 0 0 8 8 6 0 Tetratricopeptide repeat F-box_4 PF15966.5 PRP73490.1 - 0.00035 20.4 0.6 0.0047 16.8 0.0 2.6 3 0 0 3 3 3 1 F-box Ank_4 PF13637.6 PRP73490.1 - 0.00041 20.9 0.3 3.8 8.2 0.0 4.7 3 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP73490.1 - 0.0013 19.3 0.1 0.0048 17.5 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box PF00646.33 PRP73490.1 - 0.0061 16.4 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP73490.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Zip PF02535.22 PRP73493.1 - 2.4e-23 82.9 18.8 2.3e-19 69.8 4.4 2.2 1 1 0 2 2 2 2 ZIP Zinc transporter Arm PF00514.23 PRP73496.1 - 2.1e-11 43.5 14.1 0.008 16.2 0.1 10.6 12 0 0 12 12 12 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PRP73496.1 - 4.6e-07 29.5 10.7 0.054 13.8 0.0 7.2 9 0 0 9 9 9 2 HEAT repeat Atx10homo_assoc PF09759.9 PRP73496.1 - 0.012 15.6 7.4 0.23 11.5 0.3 5.6 7 2 3 10 10 10 0 Spinocerebellar ataxia type 10 protein domain Ig_J_chain PF15097.6 PRP73496.1 - 0.049 13.5 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 Immunoglobulin J chain HEAT_EZ PF13513.6 PRP73496.1 - 0.094 13.2 11.7 8 7.1 0.0 6.7 7 1 1 8 8 8 0 HEAT-like repeat UNC45-central PF11701.8 PRP73496.1 - 0.14 12.1 3.1 1.2 9.1 1.3 2.8 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central RIX1 PF08167.12 PRP73496.1 - 0.14 11.9 2.6 12 5.6 0.4 4.3 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis CFEM PF05730.11 PRP73496.1 - 0.56 10.3 2.9 27 4.9 0.0 3.1 3 0 0 3 3 3 0 CFEM domain PcfK PF14058.6 PRP73496.1 - 1.3 9.3 24.6 0.16 12.3 15.1 2.7 2 0 0 2 2 2 0 PcfK-like protein EF-hand_1 PF00036.32 PRP73497.1 - 1.3e-10 40.0 3.5 4e-05 22.8 0.5 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP73497.1 - 2.1e-10 39.7 2.2 0.00043 20.0 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP73497.1 - 2.3e-08 33.1 3.3 0.0024 17.3 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PRP73497.1 - 2.8e-08 34.1 10.4 5.1e-06 26.9 5.2 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP73497.1 - 6.9e-06 25.8 6.3 0.0092 15.8 1.7 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 PRP73497.1 - 0.098 12.5 0.9 2.3 8.1 0.0 2.8 3 0 0 3 3 3 0 EF hand DUF3506 PF12014.8 PRP73499.1 - 1.4e-14 54.2 0.0 4.2e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 PRP73499.1 - 3.6e-08 33.1 6.4 8.8e-08 31.9 6.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP73499.1 - 4.7e-07 29.6 3.5 1.1e-06 28.4 3.5 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 PRP73499.1 - 0.25 11.2 1.1 0.67 9.9 1.1 1.7 1 0 0 1 1 1 0 F-box zinc_ribbon_2 PF13240.6 PRP73500.1 - 7.9e-06 25.4 1.9 1.3e-05 24.7 1.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 PRP73500.1 - 1.6e-05 24.1 2.6 3.1e-05 23.2 2.6 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 PRP73500.1 - 5.5e-05 23.1 1.1 9.5e-05 22.4 1.1 1.4 1 0 0 1 1 1 1 Double zinc ribbon Nudix_N_2 PF14803.6 PRP73500.1 - 0.0048 16.8 4.7 0.69 9.9 0.2 2.3 2 0 0 2 2 2 2 Nudix N-terminal zinc_ribbon_15 PF17032.5 PRP73500.1 - 0.2 12.5 3.1 0.45 11.3 3.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family UPF0547 PF10571.9 PRP73500.1 - 1.6 8.9 7.4 7.7 6.7 1.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.16 PRP73500.1 - 8.4 6.4 6.3 24 4.9 0.6 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit PknG_rubred PF16919.5 PRP73500.1 - 8.8 6.5 9.0 0.98 9.6 0.5 2.7 2 1 1 3 3 3 0 Protein kinase G rubredoxin domain Aminotran_3 PF00202.21 PRP73501.1 - 9.1e-126 419.8 0.0 1.2e-125 419.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III TraB PF01963.17 PRP73501.1 - 0.0045 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 TraB family Aminotran_1_2 PF00155.21 PRP73501.1 - 0.0092 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II FTHFS PF01268.19 PRP73501.1 - 0.093 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Kazal_1 PF00050.21 PRP73502.1 - 9.8 6.3 10.9 13 5.9 2.4 3.5 3 1 0 3 3 3 0 Kazal-type serine protease inhibitor domain Peroxidase_2 PF01328.17 PRP73503.1 - 1.4e-50 172.4 0.0 2.2e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 Tox-ODYAM1 PF15642.6 PRP73503.1 - 0.035 13.1 0.3 0.052 12.5 0.3 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus MNE1 PF13762.6 PRP73503.1 - 0.048 13.7 0.9 0.62 10.0 0.8 2.0 1 1 1 2 2 2 0 Mitochondrial splicing apparatus component RhoGEF PF00621.20 PRP73504.1 - 6.2e-26 91.7 4.3 2.1e-25 90.0 4.3 2.0 1 0 0 1 1 1 1 RhoGEF domain Ras PF00071.22 PRP73504.1 - 5.8e-10 39.0 0.0 1.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Ras family C1_1 PF00130.22 PRP73504.1 - 6e-09 35.6 4.6 6e-09 35.6 4.6 3.3 3 1 1 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) COPI_C PF06957.11 PRP73504.1 - 8e-07 28.2 6.5 4.7e-06 25.6 6.5 2.1 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Roc PF08477.13 PRP73504.1 - 0.00051 20.2 0.0 0.0021 18.2 0.0 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 PRP73504.1 - 0.068 13.6 0.1 0.21 12.0 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair IQ PF00612.27 PRP73504.1 - 0.068 13.0 3.3 0.16 11.9 3.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif RsgA_GTPase PF03193.16 PRP73504.1 - 0.076 12.9 0.2 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 RsgA GTPase EF-hand_8 PF13833.6 PRP73504.1 - 0.15 11.9 1.0 4.3 7.3 0.3 3.0 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 PRP73504.1 - 0.19 11.8 0.6 0.84 9.7 0.6 2.1 1 0 0 1 1 1 0 EF-hand domain Usp PF00582.26 PRP73505.1 - 2.4e-22 79.9 0.0 3.5e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family GAF PF01590.26 PRP73506.1 - 3.5e-11 43.8 0.0 5.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain EFP_N PF08207.12 PRP73506.1 - 3.4e-09 36.6 0.1 7.6e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain GAF_2 PF13185.6 PRP73506.1 - 2.1e-06 28.1 0.0 3.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 GAF domain Elong-fact-P_C PF09285.11 PRP73506.1 - 0.00032 20.4 0.4 0.00072 19.3 0.4 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal CBM_20 PF00686.19 PRP73507.1 - 1.5e-13 50.5 0.0 3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain zf-C3HC4_3 PF13920.6 PRP73507.1 - 9.4e-12 44.6 7.1 1.6e-11 43.9 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP73507.1 - 3.7e-07 29.9 6.2 6.5e-07 29.1 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF4351 PF14261.6 PRP73507.1 - 0.026 14.6 1.8 0.042 13.9 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) zf-RING_2 PF13639.6 PRP73507.1 - 0.069 13.5 6.8 0.14 12.5 6.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 PRP73507.1 - 0.083 12.8 7.2 0.16 11.9 7.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 PRP73507.1 - 0.19 12.0 6.8 0.41 10.8 6.8 1.6 1 0 0 1 1 1 0 K-box region BORCS6 PF10157.9 PRP73507.1 - 0.19 11.9 4.7 0.31 11.3 4.7 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF4094 PF13334.6 PRP73507.1 - 0.2 12.1 0.2 0.2 12.1 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) SlyX PF04102.12 PRP73507.1 - 5.2 7.8 6.9 67 4.2 6.9 2.3 1 1 0 1 1 1 0 SlyX Pkinase_Tyr PF07714.17 PRP73508.1 - 1.1e-50 172.3 0.0 2e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP73508.1 - 5.2e-50 170.2 0.0 1.2e-49 169.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP73508.1 - 1.7e-15 56.9 0.1 6.2e-15 55.1 0.1 2.1 1 0 0 1 1 1 1 SH2 domain TPR_14 PF13428.6 PRP73508.1 - 1.9e-09 37.6 14.8 0.035 14.9 0.4 7.3 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP73508.1 - 5.8e-09 35.5 1.1 2.1 8.8 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP73508.1 - 1e-06 29.3 14.9 0.034 14.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat PH PF00169.29 PRP73508.1 - 2.9e-06 27.7 3.7 3.5e-05 24.3 0.5 3.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 PRP73508.1 - 0.00018 21.9 0.3 0.0007 20.0 0.3 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain TPR_17 PF13431.6 PRP73508.1 - 0.0011 19.2 0.5 14 6.4 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP73508.1 - 0.0013 18.7 15.6 5 7.5 0.1 7.3 7 1 0 7 7 7 1 Tetratricopeptide repeat C2 PF00168.30 PRP73508.1 - 0.0017 18.6 0.0 0.046 14.0 0.0 2.9 2 0 0 2 2 2 1 C2 domain TPR_19 PF14559.6 PRP73508.1 - 0.0022 18.5 13.5 1.3 9.6 0.1 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP73508.1 - 0.009 16.2 9.1 0.65 10.3 0.2 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PRP73508.1 - 0.012 15.3 1.4 0.088 12.5 0.3 3.2 3 0 0 3 3 2 0 TPR repeat TPR_12 PF13424.6 PRP73508.1 - 0.017 15.4 10.1 0.29 11.4 0.1 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat Kdo PF06293.14 PRP73508.1 - 0.098 12.0 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim54 PF11711.8 PRP73508.1 - 0.15 10.8 14.0 0.01 14.6 5.0 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TPR_1 PF00515.28 PRP73508.1 - 4.6 7.2 9.6 55 3.8 0.0 5.2 7 0 0 7 7 6 0 Tetratricopeptide repeat RGS PF00615.19 PRP73510.1 - 6.9e-17 61.8 0.2 6.3e-16 58.7 0.2 2.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain PH PF00169.29 PRP73510.1 - 3.8e-08 33.8 0.7 3.8e-08 33.8 0.7 2.5 2 1 1 3 3 3 1 PH domain Apolipoprotein PF01442.18 PRP73510.1 - 0.14 12.0 0.8 0.37 10.6 0.8 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain THOC7 PF05615.13 PRP73510.1 - 9.6 6.5 7.7 7.2 6.9 0.2 2.7 3 0 0 3 3 3 0 Tho complex subunit 7 Pro_isomerase PF00160.21 PRP73511.1 - 8.1e-54 182.2 0.0 9.1e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NAD_binding_10 PF13460.6 PRP73512.1 - 4.9e-11 42.9 0.1 2e-10 40.8 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PRP73512.1 - 1.3e-08 34.7 0.1 9.8e-07 28.6 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PRP73512.1 - 7.1e-06 25.7 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 PRP73512.1 - 0.00035 20.9 0.2 0.00071 19.8 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 PRP73512.1 - 0.0012 19.2 0.1 0.0027 18.2 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 PRP73512.1 - 0.0017 18.5 0.0 0.0037 17.4 0.0 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 PRP73512.1 - 0.003 16.7 0.1 0.004 16.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PRP73512.1 - 0.0048 16.1 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Ldh_1_N PF00056.23 PRP73512.1 - 0.012 15.7 0.1 0.052 13.6 0.1 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 PRP73512.1 - 0.022 13.9 0.1 0.058 12.5 0.1 1.5 1 1 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 PRP73512.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PUF PF00806.19 PRP73515.1 - 2.3e-57 187.6 17.9 6.2e-08 31.9 0.1 8.7 7 1 0 8 8 8 8 Pumilio-family RNA binding repeat Torus PF16131.5 PRP73515.1 - 2.2e-06 28.3 0.1 6.4e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 PRP73515.1 - 4.1e-06 26.5 5.3 4.1e-06 26.5 5.3 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PRP73515.1 - 9.6e-05 22.3 7.9 0.00024 21.0 7.9 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PRP73515.1 - 0.00034 20.4 4.2 0.0008 19.3 4.2 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PRP73515.1 - 0.019 15.4 3.9 0.058 13.9 3.9 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CPL PF08144.11 PRP73515.1 - 0.026 14.9 2.8 25 5.2 0.0 4.1 1 1 4 5 5 5 0 CPL (NUC119) domain DUF3683 PF12447.8 PRP73515.1 - 0.095 12.8 0.0 0.66 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) Tetraspanin PF00335.20 PRP73516.1 - 0.0044 16.8 19.5 0.0094 15.7 19.5 1.6 1 1 0 1 1 1 1 Tetraspanin family MerC PF03203.14 PRP73516.1 - 0.92 10.0 15.5 4.3 7.8 15.5 1.9 1 1 0 1 1 1 0 MerC mercury resistance protein DUF2157 PF09925.9 PRP73516.1 - 2 8.2 16.4 5.9 6.7 16.5 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF5305 PF17231.2 PRP73516.1 - 6.1 6.2 0.0 6.1 6.2 0.0 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5305) Cir_N PF10197.9 PRP73517.1 - 5e-11 42.6 9.6 5e-11 42.6 9.6 7.5 5 1 1 6 6 6 2 N-terminal domain of CBF1 interacting co-repressor CIR GDP_Man_Dehyd PF16363.5 PRP73519.1 - 1.7e-49 169.1 0.0 8.2e-49 166.8 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PRP73519.1 - 7.9e-42 143.4 0.0 9.8e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PRP73519.1 - 3.4e-11 42.8 0.0 4.7e-05 22.7 0.0 2.3 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PRP73519.1 - 3.6e-09 36.2 0.0 0.0013 18.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 PRP73519.1 - 5.3e-09 35.5 0.0 7.4e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PRP73519.1 - 0.00035 19.8 0.0 0.00058 19.1 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Colipase-like PF15083.6 PRP73520.1 - 6.1 7.0 30.6 5.8 7.1 16.9 2.4 1 1 1 2 2 2 0 Colipase-like Glyco_transf_28 PF03033.20 PRP73521.1 - 1.2e-24 86.9 0.0 2.5e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 PRP73521.1 - 1.5e-19 69.9 2.9 1.2e-14 54.1 0.2 3.7 4 0 0 4 4 4 2 GRAM domain PH PF00169.29 PRP73521.1 - 8.7e-14 51.9 0.1 2.4e-13 50.5 0.1 1.8 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 PRP73521.1 - 1.9e-08 33.6 0.0 8e-08 31.5 0.0 1.9 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PRP73521.1 - 1.2e-05 25.4 0.2 2.7e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain PH_11 PF15413.6 PRP73521.1 - 2.4e-05 24.7 0.1 0.00022 21.6 0.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 PRP73521.1 - 0.0016 18.7 0.0 0.0046 17.3 0.0 1.8 1 0 0 1 1 1 1 Plant pleckstrin homology-like region Glyco_transf_4 PF13439.6 PRP73521.1 - 0.01 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PH_4 PF15404.6 PRP73521.1 - 0.035 13.9 0.0 0.035 13.9 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain PH_6 PF15406.6 PRP73521.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Morc6_S5 PF17942.1 PRP73522.1 - 2.2e-12 47.2 0.0 3.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like HATPase_c_3 PF13589.6 PRP73522.1 - 1.2e-07 31.6 0.0 1.2e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AT_hook PF02178.19 PRP73522.1 - 0.015 15.1 5.8 0.26 11.3 5.0 3.1 2 0 0 2 2 2 0 AT hook motif BRCT PF00533.26 PRP73522.1 - 0.022 15.1 0.0 0.31 11.5 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Poty_PP PF08440.10 PRP73522.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein HVSL PF09749.9 PRP73523.1 - 7e-34 117.4 0.0 9.3e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein MRP-S34 PF16053.5 PRP73523.1 - 0.036 13.7 0.8 0.059 13.0 0.8 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 Tfb5 PF06331.12 PRP73523.1 - 0.13 12.2 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 CDC27 PF09507.10 PRP73524.1 - 0.0062 16.0 6.6 0.0084 15.5 6.6 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Pex14_N PF04695.13 PRP73524.1 - 3 8.5 10.0 7.9 7.1 10.0 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CTNNBL PF08216.11 PRP73525.1 - 3.8e-32 110.5 1.0 3.8e-32 110.5 1.0 2.7 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear RICTOR_N PF14664.6 PRP73525.1 - 0.0024 16.9 0.1 0.0098 14.9 0.0 2.0 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term MotA_ExbB PF01618.16 PRP73525.1 - 0.0042 16.8 2.1 0.24 11.2 0.0 3.6 2 2 1 3 3 3 1 MotA/TolQ/ExbB proton channel family Atx10homo_assoc PF09759.9 PRP73525.1 - 0.033 14.2 2.3 11 6.1 0.0 4.0 2 1 3 5 5 5 0 Spinocerebellar ataxia type 10 protein domain DUF2511 PF10709.9 PRP73525.1 - 0.09 13.1 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2511) PNPase PF03726.14 PRP73525.1 - 1.2 9.6 8.8 0.52 10.8 2.7 3.1 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF2951 PF11166.8 PRP73525.1 - 1.4 9.2 5.7 0.5 10.6 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Pyridoxal_deC PF00282.19 PRP73528.1 - 0.00021 20.1 1.5 0.00085 18.1 0.0 2.5 4 0 0 4 4 4 1 Pyridoxal-dependent decarboxylase conserved domain PhyH PF05721.13 PRP73529.1 - 7.6e-28 98.2 0.0 1.5e-27 97.2 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LRR_4 PF12799.7 PRP73531.1 - 2.8e-10 40.3 9.0 0.00012 22.4 1.4 5.0 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP73531.1 - 8.7e-10 38.2 8.7 6.5e-06 25.8 1.2 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 PRP73531.1 - 6.2e-09 35.2 9.2 0.085 12.9 0.1 6.8 7 0 0 7 7 7 4 Leucine Rich repeat F-box-like PF12937.7 PRP73531.1 - 7.4e-06 25.8 0.3 1.4e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP73531.1 - 1.3e-05 25.0 1.2 3e-05 23.8 1.2 1.6 1 0 0 1 1 1 1 F-box domain LRR_9 PF14580.6 PRP73531.1 - 1.9e-05 24.3 3.1 0.0037 16.8 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 PRP73531.1 - 0.072 13.7 2.6 10 7.1 0.4 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat DUF2456 PF10445.9 PRP73532.1 - 0.0012 18.8 0.2 0.0012 18.8 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) EI24 PF07264.11 PRP73532.1 - 0.17 12.1 9.4 0.22 11.7 1.1 2.1 1 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) HATPase_c PF02518.26 PRP73534.1 - 2.3e-30 105.3 0.4 4.9e-30 104.3 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP73534.1 - 8.3e-30 103.2 0.4 4.5e-26 91.2 0.5 2.9 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 PRP73534.1 - 1.3e-16 60.4 0.1 4.2e-16 58.7 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP73534.1 - 0.047 13.5 0.3 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FleQ PF06490.11 PRP73534.1 - 0.09 13.2 0.0 0.5 10.8 0.0 2.3 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ TGT PF01702.18 PRP73535.1 - 1.3e-70 238.3 0.0 2.4e-70 237.4 0.0 1.3 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase DSPc PF00782.20 PRP73537.1 - 2.4e-15 56.5 0.0 5.4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 PRP73537.1 - 3e-08 34.2 0.0 4.2e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 PRP73537.1 - 4.7e-06 26.3 0.0 8.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PRP73537.1 - 0.00029 21.0 0.0 0.00087 19.4 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PRP73537.1 - 0.012 15.6 0.4 0.041 13.9 0.1 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF773 PF05600.12 PRP73537.1 - 0.22 10.2 0.1 0.33 9.6 0.1 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Metallophos PF00149.28 PRP73538.1 - 5.1e-26 92.4 0.0 1.3e-25 91.1 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA PF00004.29 PRP73539.1 - 7.2e-39 133.2 0.0 1.3e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 PRP73539.1 - 2.6e-13 49.8 0.0 7e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 PRP73539.1 - 3e-08 33.3 0.6 3.9e-07 29.8 0.0 2.9 3 0 0 3 3 3 1 AAA+ lid domain MIT PF04212.18 PRP73539.1 - 1.7e-07 31.2 0.4 4.7e-07 29.8 0.2 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 PRP73539.1 - 3.4e-07 30.1 0.0 7.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PRP73539.1 - 3.2e-06 27.4 0.0 8.5e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PRP73539.1 - 3.3e-05 23.9 0.1 0.00032 20.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 PRP73539.1 - 0.00014 21.8 0.1 0.23 11.3 0.0 2.5 1 1 1 2 2 2 2 NACHT domain AAA_2 PF07724.14 PRP73539.1 - 0.00015 21.9 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 PRP73539.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 PRP73539.1 - 0.00034 21.0 0.1 0.001 19.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 PRP73539.1 - 0.0016 19.0 0.0 0.0059 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Aida_N PF08910.10 PRP73539.1 - 0.0019 18.6 0.1 0.0087 16.4 0.1 2.0 2 0 0 2 2 2 1 Aida N-terminus Bac_DnaA PF00308.18 PRP73539.1 - 0.0034 17.3 0.0 0.014 15.2 0.0 1.9 1 1 0 1 1 1 1 Bacterial dnaA protein TIP49 PF06068.13 PRP73539.1 - 0.0036 16.5 0.0 0.0085 15.3 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 PRP73539.1 - 0.0042 16.8 0.1 0.023 14.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PRP73539.1 - 0.0066 16.0 0.0 0.055 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP73539.1 - 0.0099 16.1 1.6 0.2 11.9 0.4 2.9 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PRP73539.1 - 0.02 14.7 0.7 0.057 13.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PRP73539.1 - 0.041 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 PRP73539.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 PRP73539.1 - 0.049 13.3 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 PRP73539.1 - 0.067 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 PRP73539.1 - 0.1 13.0 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 PRP73539.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 PRP73539.1 - 0.12 11.7 0.0 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 PRP73540.1 - 6.8e-44 149.7 0.5 6.8e-44 149.7 0.5 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP73540.1 - 4.1e-33 114.0 0.0 3.6e-32 111.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 PRP73540.1 - 0.00035 20.9 1.0 0.0016 18.7 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP73540.1 - 0.00038 20.2 0.1 0.00065 19.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PRP73540.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 PRP73540.1 - 0.0025 17.3 0.1 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_22 PF13401.6 PRP73540.1 - 0.0077 16.5 0.3 0.037 14.3 0.3 2.0 1 1 0 1 1 1 1 AAA domain tRNA-synt_1b PF00579.25 PRP73540.1 - 0.011 15.1 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) CMS1 PF14617.6 PRP73540.1 - 0.036 13.4 0.2 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.21 PRP73540.1 - 0.052 13.1 0.3 0.068 12.7 0.3 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 PRP73540.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Helicase BATS PF06968.13 PRP73540.1 - 0.095 12.9 0.0 0.33 11.1 0.0 1.9 1 1 1 2 2 2 0 Biotin and Thiamin Synthesis associated domain DUF1992 PF09350.10 PRP73541.1 - 8e-14 51.6 0.2 8e-14 51.6 0.2 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1992) TraC_F_IV PF11130.8 PRP73541.1 - 0.011 15.3 0.5 0.015 14.9 0.5 1.2 1 0 0 1 1 1 0 F pilus assembly Type-IV secretion system for plasmid transfer FtsX_ECD PF18075.1 PRP73541.1 - 0.023 15.3 0.1 4.3 8.0 0.0 2.3 2 0 0 2 2 2 0 FtsX extracellular domain Laminin_II PF06009.12 PRP73541.1 - 0.086 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF4164 PF13747.6 PRP73541.1 - 0.18 12.1 0.2 0.18 12.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) PA14 PF07691.12 PRP73542.1 - 3.3e-08 33.5 0.0 8.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 PRP73542.1 - 1.9e-06 27.6 2.5 1.9e-06 27.6 2.5 7.6 9 1 1 10 10 10 1 Dictyostelium (slime mold) repeat FAD_binding_7 PF03441.14 PRP73543.1 - 1.6e-73 246.5 0.7 2.8e-73 245.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PRP73543.1 - 3.9e-39 134.3 0.0 4.1e-38 131.0 0.0 2.2 2 0 0 2 2 2 1 DNA photolyase MPM1 PF17234.2 PRP73543.1 - 0.12 12.6 14.9 0.24 11.6 14.9 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Nop14 PF04147.12 PRP73543.1 - 1.6 6.9 33.5 2 6.5 33.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 PRP73543.1 - 1.8 7.9 31.8 0.87 9.0 28.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Smg8_Smg9 PF10220.9 PRP73543.1 - 6.2 5.0 8.7 8.9 4.5 8.7 1.2 1 0 0 1 1 1 0 Smg8_Smg9 TPR_2 PF07719.17 PRP73544.1 - 4.3e-16 57.7 14.5 0.00024 20.9 0.1 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 PRP73544.1 - 8.3e-15 53.9 14.0 0.00016 21.3 0.1 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 PRP73544.1 - 7.2e-12 45.4 4.8 0.0022 18.3 0.4 4.8 3 1 3 6 6 6 4 Tetratricopeptide repeat SET PF00856.28 PRP73544.1 - 1.3e-08 35.4 0.0 1.3e-08 35.4 0.0 2.8 3 2 0 3 3 3 1 SET domain TPR_11 PF13414.6 PRP73544.1 - 6.1e-07 29.0 0.5 0.62 9.8 0.1 4.9 5 0 0 5 5 5 2 TPR repeat TPR_9 PF13371.6 PRP73544.1 - 5.1e-06 26.6 0.1 0.0023 18.0 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP73544.1 - 7e-05 23.3 1.4 7.9 7.6 0.0 5.0 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP73544.1 - 0.00019 22.0 0.1 0.58 10.8 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP73544.1 - 0.00024 21.1 11.9 0.11 12.7 0.4 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 PRP73544.1 - 0.00029 20.6 6.1 0.067 13.1 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.9 PRP73544.1 - 0.00076 19.2 12.7 0.042 13.6 2.4 3.6 2 2 1 3 3 3 2 26S proteasome subunit RPN7 zf-C3HC PF07967.13 PRP73544.1 - 0.0044 17.1 0.3 0.015 15.4 0.3 1.9 1 0 0 1 1 1 1 C3HC zinc finger-like SHNi-TPR PF10516.9 PRP73544.1 - 0.055 12.9 1.8 33 4.0 0.0 4.1 4 0 0 4 4 4 0 SHNi-TPR FERM_C PF09380.10 PRP73544.1 - 0.099 13.0 0.2 1 9.8 0.0 2.7 3 0 0 3 3 3 0 FERM C-terminal PH-like domain TPR_7 PF13176.6 PRP73544.1 - 0.31 11.2 6.5 61 4.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat FliJ PF02050.16 PRP73544.1 - 0.59 10.4 6.3 0.44 10.8 1.4 2.9 2 0 0 2 2 2 0 Flagellar FliJ protein MIT PF04212.18 PRP73544.1 - 1.4 9.0 11.8 2.2 8.4 0.5 4.3 4 2 0 4 4 4 0 MIT (microtubule interacting and transport) domain HA2 PF04408.23 PRP73545.1 - 1 9.6 3.1 1.7 9.0 3.1 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) TPR_2 PF07719.17 PRP73546.1 - 9.7e-10 37.8 0.0 0.0023 17.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP73546.1 - 6.2e-08 32.1 0.1 0.0007 19.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP73546.1 - 6.4e-07 29.9 0.0 0.00017 22.2 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP73546.1 - 3.8e-06 26.5 0.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 TPR repeat BTAD PF03704.17 PRP73546.1 - 5.6e-05 23.6 0.4 0.15 12.5 0.1 3.0 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_12 PF13424.6 PRP73546.1 - 7.9e-05 22.9 0.0 0.03 14.6 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP73546.1 - 0.00048 20.7 0.1 0.84 10.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP73546.1 - 0.00058 20.0 0.3 0.23 11.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP73546.1 - 0.00067 19.8 0.2 0.0032 17.6 0.2 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 PRP73546.1 - 0.0038 17.3 0.0 4.9 7.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat SET PF00856.28 PRP73546.1 - 0.016 15.6 0.8 0.05 14.0 0.8 2.0 1 1 0 1 1 1 0 SET domain TPR_6 PF13174.6 PRP73546.1 - 0.042 14.5 0.1 29 5.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP73546.1 - 0.094 12.8 0.1 1.5 9.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 PRP73547.1 - 3.6e-69 233.1 0.0 8.9e-69 231.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73547.1 - 2.5e-33 115.5 0.0 2.2e-26 92.7 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP73547.1 - 5.4e-07 29.2 0.1 0.00029 20.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PRP73547.1 - 2.8e-06 27.5 0.0 7.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP73547.1 - 4.7e-05 22.3 0.0 0.00015 20.7 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP73547.1 - 0.00059 19.3 0.0 0.0016 17.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP73547.1 - 0.001 18.1 0.1 0.0021 17.1 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PRP73547.1 - 0.018 14.1 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 PRP73547.1 - 0.091 12.4 0.2 7.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ribosomal_L21p PF00829.21 PRP73548.1 - 9.6e-34 115.7 3.3 1.4e-33 115.2 3.3 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FHA PF00498.26 PRP73549.1 - 2.2e-11 44.0 0.0 4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain NIBRIN_BRCT_II PF16508.5 PRP73549.1 - 3.1e-06 27.5 1.7 1.7e-05 25.2 0.1 3.1 2 1 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein BRCT PF00533.26 PRP73549.1 - 0.01 16.2 0.0 15 6.1 0.0 3.4 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Mito_carr PF00153.27 PRP73550.1 - 5.7e-66 218.5 2.0 1.9e-22 78.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L23eN PF03939.13 PRP73551.1 - 3.2e-16 59.2 6.8 3.2e-16 59.2 6.8 3.1 3 1 0 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 PRP73551.1 - 5e-13 49.2 1.6 5e-13 49.2 1.6 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 CsoS2_M PF12288.8 PRP73551.1 - 0.097 12.1 9.9 0.15 11.4 9.9 1.3 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region MatE PF01554.18 PRP73552.1 - 1.9e-59 199.9 29.5 1.3e-33 115.9 8.7 3.6 3 1 1 4 4 4 2 MatE Polysacc_synt_C PF14667.6 PRP73552.1 - 7.9e-08 32.5 12.2 7.9e-08 32.5 12.2 3.4 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain UPF0242 PF06785.11 PRP73552.1 - 0.07 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_S28 PF05577.12 PRP73554.1 - 7.6e-85 285.3 8.5 1.2e-84 284.6 8.5 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 PRP73554.1 - 2.1e-05 23.9 0.0 4.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PRP73554.1 - 0.00062 19.3 0.1 0.0014 18.1 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 PRP73554.1 - 0.08 12.4 1.5 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase Suf PF05843.14 PRP73554.1 - 6.6 6.6 6.1 10 6.0 4.7 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Velvet PF11754.8 PRP73555.1 - 0.0027 17.7 6.3 0.0057 16.6 6.3 1.5 1 0 0 1 1 1 1 Velvet factor LRR19-TM PF15176.6 PRP73555.1 - 0.048 13.6 0.1 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain PI3K_1B_p101 PF10486.9 PRP73555.1 - 0.051 11.4 4.2 0.067 11.0 4.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4614 PF15391.6 PRP73555.1 - 0.069 13.1 14.1 0.14 12.1 14.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) AJAP1_PANP_C PF15298.6 PRP73555.1 - 0.071 13.3 12.9 0.13 12.5 12.9 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF1180 PF06679.12 PRP73555.1 - 0.18 12.2 3.9 0.44 10.9 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SWI-SNF_Ssr4 PF08549.10 PRP73555.1 - 0.21 10.2 4.9 0.3 9.7 4.9 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) FAM199X PF15814.5 PRP73555.1 - 0.6 9.1 12.4 1.2 8.2 12.4 1.4 1 0 0 1 1 1 0 Protein family FAM199X Pex14_N PF04695.13 PRP73555.1 - 0.95 10.1 8.3 0.11 13.2 2.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RAP1 PF07218.11 PRP73555.1 - 1.1 7.4 12.2 1.7 6.8 12.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MGC-24 PF05283.11 PRP73555.1 - 4.1 7.9 16.1 8.8 6.8 16.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 PRP73555.1 - 6.8 6.7 29.0 14 5.6 29.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Skp1_POZ PF03931.15 PRP73556.1 - 4.2e-12 46.1 0.1 2.3e-06 27.7 0.1 2.5 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Skp1 PF01466.19 PRP73556.1 - 1.2e-07 31.7 0.0 1.2e-07 31.7 0.0 3.1 3 0 0 3 3 3 1 Skp1 family, dimerisation domain SR-25 PF10500.9 PRP73556.1 - 0.4 10.2 9.1 0.3 10.7 7.4 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cadherin_tail PF15974.5 PRP73556.1 - 0.83 10.0 6.6 1.6 9.0 6.6 1.5 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region AATF-Che1 PF13339.6 PRP73556.1 - 1.3 9.7 6.9 5 7.8 6.8 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor PEPCK_ATP PF01293.20 PRP73557.1 - 3.8e-222 738.0 0.0 5.1e-222 737.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase TPR_8 PF13181.6 PRP73557.1 - 6.2e-25 85.3 31.7 8.8e-07 28.7 0.0 10.1 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 PRP73557.1 - 1.2e-24 85.0 41.3 6.4e-07 28.9 0.0 9.0 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 PRP73557.1 - 2.6e-23 80.2 38.0 0.0002 21.2 0.1 9.9 10 0 0 10 10 9 7 Tetratricopeptide repeat ANAPC8 PF04049.13 PRP73557.1 - 5.5e-23 81.6 12.3 6e-16 58.8 2.8 3.7 2 2 1 3 3 3 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_14 PF13428.6 PRP73557.1 - 1.7e-19 68.8 20.5 2.8e-05 24.6 0.1 8.8 5 3 4 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 PRP73557.1 - 4.9e-16 58.8 23.3 7.1e-07 29.4 1.8 5.8 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 PRP73557.1 - 1.5e-14 54.3 21.8 3.2e-05 24.5 0.0 7.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 PRP73557.1 - 6.1e-14 50.9 20.2 0.033 14.2 0.2 8.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 PRP73557.1 - 7.1e-12 45.7 18.9 0.0028 18.1 0.2 6.9 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP73557.1 - 5.7e-11 41.9 18.6 6.6e-09 35.3 0.6 6.4 4 2 2 6 6 6 2 TPR repeat TPR_17 PF13431.6 PRP73557.1 - 2.1e-10 40.2 20.9 0.0052 17.1 0.0 9.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP73557.1 - 3e-10 40.1 24.9 0.4 11.4 0.6 9.2 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 PRP73557.1 - 4.7e-07 29.8 10.6 0.0034 17.5 0.2 4.9 5 1 2 7 7 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP73557.1 - 7.4e-07 29.3 26.4 0.047 13.9 4.8 6.2 3 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 PRP73557.1 - 1.9e-06 27.6 18.8 0.2 11.6 0.3 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_33 PF13671.6 PRP73557.1 - 0.0014 18.8 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ChAPs PF09295.10 PRP73557.1 - 0.0039 16.2 3.6 0.72 8.8 0.0 3.4 1 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 PRP73557.1 - 0.0064 15.7 13.9 0.028 13.6 5.7 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.12 PRP73557.1 - 0.016 15.9 1.4 19 6.1 0.0 4.0 3 0 0 3 3 2 0 Sel1 repeat DUF3856 PF12968.7 PRP73557.1 - 0.049 13.7 4.4 0.9 9.6 0.1 3.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) AAA_16 PF13191.6 PRP73557.1 - 0.053 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PcfK PF14058.6 PRP73557.1 - 0.14 12.4 0.6 2.5 8.4 0.3 2.3 1 1 1 2 2 2 0 PcfK-like protein BTAD PF03704.17 PRP73557.1 - 3.1 8.2 7.5 30 5.0 0.9 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Homeodomain PF00046.29 PRP73559.1 - 1.6e-12 47.1 4.6 2e-12 46.8 3.9 1.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP73559.1 - 0.00018 21.3 0.6 0.00031 20.6 0.6 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 PRP73559.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sipho_Gp157 PF05565.11 PRP73560.1 - 0.1 12.6 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 ArAE_2_N PF10337.9 PRP73561.1 - 0.062 12.3 0.1 0.07 12.1 0.1 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal RRM_1 PF00076.22 PRP73562.1 - 6.3e-34 115.6 1.7 3.4e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 PRP73562.1 - 0.0044 17.0 0.1 0.19 11.8 0.0 2.2 2 0 0 2 2 2 1 DbpA RNA binding domain OB_RNB PF08206.11 PRP73562.1 - 0.016 14.8 1.6 1.8 8.3 0.2 2.6 2 1 0 2 2 2 0 Ribonuclease B OB domain RRM_occluded PF16842.5 PRP73562.1 - 0.055 13.3 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_7 PF16367.5 PRP73562.1 - 0.1 12.8 0.0 17 5.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif ORC6 PF05460.13 PRP73562.1 - 0.72 9.1 8.0 0.98 8.6 8.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Brix PF04427.18 PRP73563.1 - 8.9e-25 87.9 0.2 1.6e-24 87.1 0.2 1.4 1 0 0 1 1 1 1 Brix domain tRNA-synt_1b PF00579.25 PRP73564.1 - 9.1e-20 71.1 0.0 2.3e-19 69.8 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) EF-hand_5 PF13202.6 PRP73565.1 - 1.4e-06 27.5 6.6 0.15 11.6 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_1 PF00036.32 PRP73565.1 - 0.00017 20.9 6.4 0.15 11.6 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PRP73565.1 - 0.00039 20.1 4.3 3.1 7.9 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 PRP73565.1 - 0.00041 20.5 5.0 0.0039 17.3 1.1 3.1 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_7 PF13499.6 PRP73565.1 - 0.0005 20.5 2.6 0.2 12.1 0.8 3.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 PRP73565.1 - 0.011 15.5 2.7 2.8 7.9 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain pair VD10_N PF08476.10 PRP73565.1 - 0.018 14.7 2.0 2.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Viral D10 N-terminal zf-CCHC PF00098.23 PRP73566.1 - 1.2e-13 50.4 26.3 0.00023 21.1 1.8 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 PRP73566.1 - 0.00035 20.2 20.7 0.13 12.0 0.7 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-C2H2_10 PF16588.5 PRP73566.1 - 0.017 14.9 9.6 0.44 10.3 2.1 2.9 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 PRP73566.1 - 0.02 14.7 25.0 0.2 11.5 0.2 4.4 4 0 0 4 4 4 0 Zinc knuckle TRAF6_Z2 PF18048.1 PRP73566.1 - 1.8 8.7 8.9 1.3 9.2 0.4 3.1 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 PHD_4 PF16866.5 PRP73566.1 - 1.9 8.6 14.5 0.4 10.8 3.0 3.1 1 1 2 3 3 3 0 PHD-finger zf-C4_ClpX PF06689.13 PRP73566.1 - 6.3 6.8 9.2 1.3 9.0 5.1 2.0 2 0 0 2 2 2 0 ClpX C4-type zinc finger DEAD PF00270.29 PRP73567.1 - 9.9e-41 139.4 0.1 1.7e-40 138.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP73567.1 - 9.9e-23 80.6 0.0 5.7e-22 78.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PRP73567.1 - 1.5e-18 66.8 0.2 3.2e-18 65.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PRP73567.1 - 1.3e-09 38.3 0.1 1.3e-09 38.3 0.1 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PRP73567.1 - 0.0028 17.9 0.6 0.02 15.2 0.3 2.5 2 1 0 2 2 2 1 AAA domain FSIP1 PF15554.6 PRP73569.1 - 5.5e-06 25.7 2.0 6.4e-06 25.5 2.0 1.1 1 0 0 1 1 1 1 FSIP1 family P4Ha_N PF08336.11 PRP73569.1 - 0.17 11.9 4.4 0.2 11.7 1.8 2.0 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PP2C_C PF07830.13 PRP73569.1 - 0.25 11.8 3.3 0.37 11.3 0.5 2.1 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain K_trans PF02705.16 PRP73570.1 - 0.0079 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 K+ potassium transporter DUF2700 PF10912.8 PRP73571.1 - 0.00051 20.1 2.7 0.0006 19.9 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2700) Imp-YgjV PF10688.9 PRP73571.1 - 0.0012 18.7 1.6 0.0014 18.4 1.6 1.0 1 0 0 1 1 1 1 Bacterial inner membrane protein NMO PF03060.15 PRP73572.1 - 8.5e-55 186.4 1.0 8.5e-55 186.4 1.0 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.25 PRP73572.1 - 2.7e-11 43.1 0.0 4.6e-10 39.0 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Rab5ip PF07019.12 PRP73572.1 - 1e-10 42.1 4.6 2.3e-10 40.9 4.6 1.6 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) FMN_dh PF01070.18 PRP73572.1 - 1.1e-08 34.5 1.0 1.8e-08 33.8 1.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 PRP73572.1 - 0.0032 16.6 1.3 0.0058 15.8 1.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 PRP73572.1 - 0.019 14.2 0.2 0.16 11.1 0.1 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase LisH PF08513.11 PRP73573.1 - 0.001 19.0 0.6 0.2 11.7 0.2 2.6 2 0 0 2 2 2 2 LisH LisH_TPL PF17814.1 PRP73573.1 - 0.001 18.7 0.2 0.38 10.4 0.0 2.8 2 0 0 2 2 2 2 LisH-like dimerisation domain Med1 PF10744.9 PRP73573.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Peptidase_M1 PF01433.20 PRP73574.1 - 3.5e-63 213.1 0.5 6e-63 212.3 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PRP73574.1 - 2.1e-25 90.0 0.4 1.2e-23 84.3 0.0 2.9 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 PRP73574.1 - 2.1e-11 44.0 0.2 6.5e-11 42.3 0.2 1.8 1 1 0 1 1 1 1 ERAP1-like C-terminal domain TM1586_NiRdase PF14512.6 PRP73575.1 - 1.9e-06 27.6 0.0 0.00014 21.5 0.0 2.3 2 0 0 2 2 2 2 Putative TM nitroreductase Nitroreductase PF00881.24 PRP73575.1 - 3.4e-05 24.0 0.4 0.048 13.7 0.0 3.6 3 1 1 4 4 4 2 Nitroreductase family Coatomer_WDAD PF04053.14 PRP73576.1 - 9.6e-125 417.1 0.7 1.3e-124 416.6 0.1 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 PRP73576.1 - 1.2e-124 416.2 0.1 1.6e-124 415.8 0.1 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 PRP73576.1 - 1.1e-43 146.3 15.9 7.6e-08 32.9 0.3 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP73576.1 - 3.2e-08 33.7 0.5 0.0024 18.1 0.0 5.2 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP73576.1 - 0.18 10.4 7.4 3.4 6.2 0.1 3.6 3 1 1 4 4 4 0 Nucleoporin Nup120/160 TPR_2 PF07719.17 PRP73576.1 - 0.77 10.0 2.1 16 5.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Gar1 PF04410.14 PRP73577.1 - 2.8e-31 108.4 0.0 2.8e-31 108.4 0.0 2.5 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Pkinase PF00069.25 PRP73577.1 - 1.1e-28 100.4 0.0 4.9e-28 98.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73577.1 - 1.7e-13 50.5 0.0 4.2e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP73577.1 - 0.0027 17.1 0.2 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Vint PF14623.6 PRP73578.1 - 1.7e-37 128.8 0.1 3e-37 128.0 0.1 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 PRP73578.1 - 1.3e-20 73.3 0.0 2.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 PRP73578.1 - 2.8e-15 57.0 0.1 6.3e-15 55.9 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP73578.1 - 1.4e-12 48.2 0.6 3.2e-12 47.0 0.6 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PRP73578.1 - 3.6e-12 46.5 1.8 4.7e-11 42.9 0.5 2.6 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PRP73578.1 - 0.00016 21.2 3.2 0.094 12.1 0.2 2.3 1 1 1 2 2 2 2 VWA domain containing CoxE-like protein Hint PF01079.20 PRP73578.1 - 0.00019 21.0 0.5 0.0015 18.1 0.1 2.2 1 1 0 2 2 2 1 Hint module YajC PF02699.15 PRP73578.1 - 0.028 14.3 1.2 0.074 12.9 1.2 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit Hint_2 PF13403.6 PRP73578.1 - 0.064 13.6 0.1 0.46 10.8 0.1 2.2 1 1 0 1 1 1 0 Hint domain vWA-TerF-like PF10138.9 PRP73578.1 - 0.073 13.2 0.3 0.19 11.8 0.3 1.6 1 1 0 1 1 1 0 vWA found in TerF C terminus Rap_GAP PF02145.15 PRP73579.1 - 1.1e-58 197.9 1.3 4.3e-58 195.9 0.1 2.4 2 1 0 2 2 2 1 Rap/ran-GAP Syja_N PF02383.18 PRP73582.1 - 1.2e-76 258.1 1.0 1.2e-76 258.1 1.0 1.7 2 0 0 2 2 2 1 SacI homology domain FAD_binding_7 PF03441.14 PRP73583.1 - 1e-49 168.7 1.9 1.5e-49 168.2 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PRP73583.1 - 1.7e-33 115.9 0.0 2.6e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase zf-C2H2_jaz PF12171.8 PRP73586.1 - 6.2e-05 23.2 1.4 6.2e-05 23.2 1.4 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP73586.1 - 0.0029 17.9 0.5 0.0029 17.9 0.5 2.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF629 PF04780.12 PRP73586.1 - 0.013 14.1 0.2 0.02 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 PRP73586.1 - 0.019 15.7 1.0 0.019 15.7 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger ARS2 PF04959.13 PRP73586.1 - 0.078 13.3 0.3 0.16 12.3 0.3 1.5 1 0 0 1 1 1 0 Arsenite-resistance protein 2 zf-3CxxC PF13695.6 PRP73586.1 - 0.37 11.3 3.6 0.95 10.0 3.6 1.8 1 0 0 1 1 1 0 Zinc-binding domain Actin_micro PF17003.5 PRP73586.1 - 0.47 9.6 2.8 0.41 9.8 0.6 1.9 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2 PF00096.26 PRP73586.1 - 4.6 7.9 8.1 0.23 12.0 1.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type LRR_4 PF12799.7 PRP73587.1 - 5.1e-07 29.9 25.9 4.6 7.8 0.1 9.9 4 2 5 11 11 11 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP73587.1 - 0.00071 19.4 12.3 0.082 13.0 0.1 8.2 9 0 0 9 9 9 1 Leucine Rich repeat RNA_pol_I_TF PF04090.12 PRP73587.1 - 0.12 11.8 0.0 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor LRR_5 PF13306.6 PRP73587.1 - 0.27 11.2 4.0 11 5.9 0.2 3.1 2 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) TBCA PF02970.16 PRP73589.1 - 2e-25 88.9 3.4 2.5e-25 88.6 3.4 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A TMCO5 PF14992.6 PRP73589.1 - 0.074 12.6 4.6 0.084 12.4 4.6 1.1 1 0 0 1 1 1 0 TMCO5 family Phage_GP20 PF06810.11 PRP73589.1 - 0.096 12.5 7.1 0.32 10.8 3.0 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF2203 PF09969.9 PRP73589.1 - 0.12 13.1 3.8 0.23 12.2 3.8 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) WD40 PF00400.32 PRP73590.1 - 3.3e-27 94.2 5.0 1.2e-05 26.0 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP73590.1 - 4.9e-12 46.0 0.0 0.012 15.9 0.0 5.0 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP73590.1 - 2e-05 23.7 0.2 0.12 11.4 0.0 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP73590.1 - 0.00014 20.7 0.1 0.31 9.6 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PRP73590.1 - 0.00032 19.6 0.5 0.47 9.1 0.1 2.2 1 1 1 2 2 2 2 Nup133 N terminal like Coatomer_WDAD PF04053.14 PRP73590.1 - 0.0022 17.1 0.3 0.19 10.7 0.1 2.2 1 1 1 2 2 2 2 Coatomer WD associated region WD40_like PF17005.5 PRP73590.1 - 0.0024 17.2 0.1 0.018 14.4 0.1 2.4 1 1 0 1 1 1 1 WD40-like domain PQQ PF01011.21 PRP73590.1 - 0.0085 16.0 0.1 0.089 12.8 0.0 2.6 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 PRP73590.1 - 0.022 14.3 0.4 0.047 13.3 0.4 1.7 1 1 0 1 1 1 0 PQQ-like domain DUF5046 PF16465.5 PRP73590.1 - 0.057 12.9 0.5 2.5 7.5 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 PRP73590.1 - 0.063 13.8 0.1 1.1 9.8 0.0 3.0 3 1 0 3 3 3 0 PQQ-like domain Pneumo_matrix PF03393.16 PRP73590.1 - 0.069 12.4 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus matrix protein EVI2A PF05399.11 PRP73590.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) SAM_decarbox PF01536.16 PRP73591.1 - 1.4e-95 320.4 0.7 2e-95 319.8 0.7 1.3 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Copine PF07002.16 PRP73591.1 - 4.6e-62 209.3 0.0 7.3e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 PRP73591.1 - 1.6e-09 38.2 0.0 3.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Pkinase_Tyr PF07714.17 PRP73592.1 - 3.5e-52 177.2 0.0 1.1e-51 175.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP73592.1 - 1.3e-36 126.3 0.0 2.1e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP73592.1 - 2.6e-34 116.8 60.9 2.3e-08 33.7 3.8 8.6 6 2 2 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 PRP73592.1 - 7.7e-27 92.9 76.3 1.3e-06 28.7 4.8 12.0 6 2 6 13 13 13 12 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP73592.1 - 3.1e-05 23.5 25.9 0.0015 18.1 0.8 5.4 2 2 3 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 PRP73592.1 - 8.4e-05 22.3 59.6 1.2 9.4 0.9 15.2 16 0 0 16 16 16 6 Leucine Rich repeat LRR_1 PF00560.33 PRP73592.1 - 0.001 19.3 56.2 0.097 13.3 0.2 15.0 13 2 1 14 14 14 2 Leucine Rich Repeat Adeno_E3_CR2 PF02439.15 PRP73592.1 - 0.22 11.3 1.1 14 5.6 0.2 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 BSD PF03909.17 PRP73593.1 - 6.3e-10 38.9 4.2 3.7e-06 26.8 0.6 3.1 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 PRP73593.1 - 7.5e-06 26.2 0.0 2.1e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain NurA PF09376.10 PRP73593.1 - 0.095 12.4 0.1 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 NurA domain rve PF00665.26 PRP73595.1 - 2.5e-10 40.6 0.0 6.3e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 PRP73595.1 - 1.5e-07 31.2 1.4 1.5e-07 31.2 1.4 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SSXT PF05030.12 PRP73595.1 - 0.15 11.8 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Glyco_tranf_2_4 PF13704.6 PRP73595.1 - 0.15 12.6 1.3 2.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family 2 RT_RNaseH PF17917.1 PRP73596.1 - 1.4e-33 115.3 0.0 2.7e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP73596.1 - 1.4e-30 105.2 0.0 3.4e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP73596.1 - 2.2e-27 96.0 0.3 6.5e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short_C2 PF13561.6 PRP73597.1 - 0.21 11.1 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP73597.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TIG PF01833.24 PRP73598.1 - 1.7e-11 44.0 8.2 6e-11 42.3 5.0 3.0 2 0 0 2 2 2 1 IPT/TIG domain RIBIOP_C PF04950.12 PRP73599.1 - 0.00029 20.4 0.1 0.00039 19.9 0.1 1.3 1 1 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Vps36_ESCRT-II PF11605.8 PRP73599.1 - 0.063 13.5 0.2 7.5 6.8 0.1 2.6 1 1 1 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 PARP PF00644.20 PRP73600.1 - 1.8e-18 66.8 0.0 2.6e-17 63.1 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Inhibitor_I29 PF08246.12 PRP73601.1 - 0.059 13.8 5.0 4.1 7.9 0.6 2.7 2 1 1 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) Clathrin PF00637.20 PRP73601.1 - 0.068 13.0 1.5 0.091 12.6 1.5 1.4 1 1 0 1 1 1 0 Region in Clathrin and VPS MULE PF10551.9 PRP73601.1 - 0.078 13.4 0.6 0.098 13.1 0.6 1.3 1 1 0 1 1 1 0 MULE transposase domain CPG4 PF15481.6 PRP73601.1 - 0.26 11.9 6.6 1.2 9.8 1.8 2.2 1 1 1 2 2 2 0 Chondroitin proteoglycan 4 GT87 PF09594.10 PRP73602.1 - 0.0059 16.3 0.1 3.8 7.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 87 PUA_3 PF17785.1 PRP73602.1 - 0.0062 16.3 0.0 5.2 7.0 0.0 2.4 2 0 0 2 2 2 2 PUA-like domain malic PF00390.19 PRP73602.1 - 0.024 14.4 0.0 9.7 5.9 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain PfkB PF00294.24 PRP73602.1 - 0.047 13.0 0.0 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 pfkB family carbohydrate kinase DUF1769 PF08588.10 PRP73602.1 - 0.053 13.7 0.1 20 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) DUF4280 PF14107.6 PRP73602.1 - 0.097 13.5 0.1 28 5.6 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4280) HPIP_like PF18524.1 PRP73602.1 - 0.22 11.3 0.0 34 4.3 0.0 2.4 2 0 0 2 2 2 0 High potential iron-sulfur protein like FadA PF09403.10 PRP73603.1 - 0.31 11.5 9.5 0.52 10.8 0.1 3.4 2 1 1 3 3 3 0 Adhesion protein FadA OmpH PF03938.14 PRP73603.1 - 1.3 9.4 11.1 0.77 10.1 7.6 2.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.7 PRP73606.1 - 1.5e-25 89.6 1.6 2.2e-06 28.2 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP73606.1 - 9.8e-18 64.0 1.8 0.00099 19.4 0.0 7.4 3 3 5 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP73606.1 - 2.3e-15 56.7 1.7 2.1e-05 25.0 0.0 6.8 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP73606.1 - 9.9e-15 53.2 1.3 1.1 10.0 0.0 8.7 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 PRP73606.1 - 5.1e-09 36.2 4.1 0.23 12.0 0.2 8.3 6 2 1 7 7 7 1 Ankyrin repeat F-box PF00646.33 PRP73606.1 - 0.00094 19.0 0.0 0.00094 19.0 0.0 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 PRP73606.1 - 0.0036 17.2 0.1 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like ASXH PF13919.6 PRP73606.1 - 0.18 11.9 0.4 20 5.2 0.0 2.6 2 0 0 2 2 2 0 Asx homology domain SWI2_SNF2 PF18766.1 PRP73607.1 - 0.047 13.4 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase GCP5-Mod21 PF14609.6 PRP73607.1 - 0.12 10.7 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Lustrin_cystein PF14625.6 PRP73608.1 - 0.00026 21.3 10.7 0.0031 17.8 3.6 2.6 2 0 0 2 2 2 2 Lustrin, cysteine-rich repeated domain ADH_zinc_N PF00107.26 PRP73609.1 - 8.4e-18 64.6 0.1 1.2e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP73609.1 - 3.1e-13 50.9 0.0 4.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP73609.1 - 0.00085 19.2 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Phage_tail_U PF06141.11 PRP73615.1 - 0.02 15.3 0.6 0.66 10.3 0.1 2.3 2 0 0 2 2 2 0 Phage minor tail protein U RNR_inhib PF08591.10 PRP73615.1 - 0.099 14.0 0.1 25 6.2 0.0 2.3 2 0 0 2 2 2 0 Ribonucleotide reductase inhibitor RepA_N PF06970.11 PRP73617.1 - 0.15 12.0 0.1 0.21 11.6 0.1 1.1 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus Borrelia_rep PF03183.13 PRP73619.1 - 0.081 12.9 2.4 0.2 11.7 2.4 1.6 1 0 0 1 1 1 0 Borrelia repeat protein BAT2_N PF07001.11 PRP73623.1 - 0.17 12.3 4.0 0.66 10.4 0.0 2.1 2 0 0 2 2 2 0 BAT2 N-terminus Hamartin PF04388.12 PRP73624.1 - 0.073 11.7 3.2 0.094 11.4 3.2 1.1 1 0 0 1 1 1 0 Hamartin protein ATG16 PF08614.11 PRP73624.1 - 0.1 12.8 3.0 0.15 12.3 3.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) MAD PF05557.13 PRP73624.1 - 0.14 10.5 0.1 0.19 10.1 0.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4140 PF13600.6 PRP73624.1 - 0.58 10.6 3.7 16 6.0 0.0 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Apolipoprotein PF01442.18 PRP73627.1 - 0.00026 20.9 1.1 0.00036 20.4 1.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PRP73627.1 - 0.00028 20.9 0.3 0.00042 20.4 0.3 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3461 PF11944.8 PRP73627.1 - 0.0054 16.9 1.1 0.0097 16.0 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3461) DUF1640 PF07798.11 PRP73627.1 - 0.0086 16.1 3.1 0.012 15.7 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) BshC PF10079.9 PRP73627.1 - 0.02 13.6 0.7 0.026 13.3 0.7 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF3810 PF12725.7 PRP73627.1 - 0.033 13.6 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Exonuc_VII_L PF02601.15 PRP73627.1 - 0.038 13.6 0.4 0.046 13.3 0.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Det1 PF09737.9 PRP73627.1 - 0.054 12.6 0.2 0.068 12.2 0.2 1.1 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 VPS38 PF17649.1 PRP73627.1 - 0.055 12.3 1.4 0.075 11.9 1.4 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Peptidase_C57 PF03290.13 PRP73627.1 - 0.067 11.9 0.2 0.081 11.6 0.2 1.1 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase SepSecS PF05889.13 PRP73627.1 - 0.074 11.7 0.1 0.079 11.6 0.1 1.1 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Fic PF02661.18 PRP73627.1 - 0.097 13.6 0.0 25 5.9 0.0 2.3 2 0 0 2 2 2 0 Fic/DOC family Fib_alpha PF08702.10 PRP73627.1 - 0.15 12.2 3.0 0.48 10.6 2.8 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 PRP73627.1 - 0.24 11.2 5.8 0.62 9.9 5.5 1.7 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF3450 PF11932.8 PRP73627.1 - 0.27 10.5 3.3 0.29 10.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fzo_mitofusin PF04799.13 PRP73627.1 - 0.28 10.7 2.0 0.65 9.5 2.0 1.5 1 1 0 1 1 1 0 fzo-like conserved region PspB PF06667.12 PRP73627.1 - 0.31 11.1 2.4 0.45 10.6 1.3 1.9 1 1 0 1 1 1 0 Phage shock protein B LidA_Long_CC PF18641.1 PRP73627.1 - 0.34 10.9 6.1 0.13 12.3 2.2 1.9 1 1 0 2 2 2 0 LidA long coiled-coil domain XhlA PF10779.9 PRP73627.1 - 4.2 7.6 6.3 32 4.8 6.3 2.4 1 1 0 1 1 1 0 Haemolysin XhlA DUF1515 PF07439.11 PRP73627.1 - 9 6.4 8.7 2.1 8.4 3.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) VirE PF05272.11 PRP73628.1 - 0.0093 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Virulence-associated protein E AAA_29 PF13555.6 PRP73628.1 - 0.034 13.9 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PRP73628.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Y_phosphatase3 PF13350.6 PRP73629.1 - 0.017 15.1 0.0 0.018 15.0 0.0 1.0 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_S78 PF04586.17 PRP73629.1 - 0.072 13.3 0.0 0.072 13.3 0.0 1.0 1 0 0 1 1 1 0 Caudovirus prohead serine protease SapB_2 PF03489.17 PRP73630.1 - 5.1e-05 23.3 0.3 0.00018 21.6 0.2 2.0 2 0 0 2 2 2 1 Saposin-like type B, region 2 UvrD-helicase PF00580.21 PRP73631.1 - 5.7e-57 193.6 1.6 5.7e-57 193.6 1.6 1.5 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 PRP73631.1 - 7e-31 107.5 0.1 1.8e-30 106.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 PRP73631.1 - 1e-16 61.3 1.4 3.4e-13 49.7 0.0 3.0 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 PRP73631.1 - 7.5e-11 42.1 0.0 2e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 PRP73631.1 - 7.4e-05 22.7 2.8 7.4e-05 22.7 2.8 2.9 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 PRP73631.1 - 0.0009 19.0 0.1 0.2 11.4 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Terminase_6 PF03237.15 PRP73631.1 - 0.0055 16.4 1.1 0.5 10.0 0.0 2.6 2 1 1 3 3 3 1 Terminase-like family Helicase_RecD PF05127.14 PRP73631.1 - 0.064 13.1 0.1 0.21 11.4 0.1 2.1 1 1 0 1 1 1 0 Helicase Scaffolding_pro PF11418.8 PRP73631.1 - 1.6 9.4 5.2 0.88 10.2 2.3 2.1 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF4164 PF13747.6 PRP73632.1 - 0.062 13.6 0.1 0.062 13.6 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.10 PRP73632.1 - 0.096 12.9 14.4 0.066 13.4 7.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase_Tyr PF07714.17 PRP73632.1 - 0.17 11.1 0.0 0.17 11.1 0.0 2.3 2 1 0 2 2 2 0 Protein tyrosine kinase SlyX PF04102.12 PRP73632.1 - 0.34 11.5 22.9 0.93 10.2 5.3 3.5 2 1 1 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 PRP73632.1 - 0.76 9.8 25.2 12 6.0 5.3 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.13 PRP73632.1 - 1 10.1 10.1 2.9 8.7 0.2 2.5 2 0 0 2 2 2 0 Occludin homology domain UPF0242 PF06785.11 PRP73632.1 - 1.1 9.4 25.5 0.072 13.2 5.0 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 PRP73632.1 - 1.7 9.3 19.9 1.1 10.0 3.3 2.9 1 1 2 3 3 3 0 Initiation control protein YabA Med9 PF07544.13 PRP73632.1 - 6.5 6.9 18.7 0.21 11.7 5.0 3.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TEX13 PF15186.6 PRP73632.1 - 6.8 6.4 12.9 0.1 12.3 3.2 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family EMP24_GP25L PF01105.24 PRP73632.1 - 9.7 6.1 7.7 0.88 9.5 1.9 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RNA_pol_Rpb1_6 PF04992.14 PRP73634.1 - 3.3e-51 173.8 0.4 3.7e-27 95.4 0.0 3.3 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_5 PF04998.17 PRP73634.1 - 8.4e-18 64.7 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_7 PF04990.12 PRP73634.1 - 2.7e-13 50.1 0.4 2.7e-13 50.1 0.4 2.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 7 tRNA-synt_2c PF01411.19 PRP73634.1 - 6e-08 31.7 0.0 0.25 9.8 0.0 4.0 3 1 1 4 4 4 4 tRNA synthetases class II (A) Ldr_toxin PF13940.6 PRP73634.1 - 0.11 12.6 0.0 25 5.0 0.0 2.5 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system UPF0731 PF14982.6 PRP73637.1 - 0.063 13.4 0.2 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 UPF0731 family DDE_Tnp_4 PF13359.6 PRP73645.1 - 5e-11 42.5 0.0 5.6e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP73645.1 - 0.013 15.1 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain Dak1_2 PF13684.6 PRP73646.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family DUF3586 PF12131.8 PRP73647.1 - 0.021 15.0 6.0 0.26 11.5 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) Pkinase PF00069.25 PRP73650.1 - 5.6e-12 45.6 0.2 1.1e-11 44.6 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73650.1 - 1.8e-10 40.5 0.2 2.7e-10 40.0 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP73650.1 - 1.5e-06 28.7 3.3 1.6e-06 28.5 0.9 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Syndecan PF01034.20 PRP73650.1 - 0.09 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain zf-MYND PF01753.18 PRP73652.1 - 4.9e-13 48.9 13.0 1.1e-12 47.8 13.0 1.6 1 0 0 1 1 1 1 MYND finger CSTF2_hinge PF14327.6 PRP73652.1 - 0.069 13.6 1.0 0.14 12.6 0.2 1.8 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 zf-C6H2 PF15801.5 PRP73652.1 - 0.38 11.1 10.3 1.4 9.3 10.3 2.1 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 PRP73652.1 - 1.7 8.8 12.4 1.9 8.7 0.4 3.2 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 S1 PF00575.23 PRP73653.1 - 4.7e-11 42.9 0.2 7.9e-11 42.1 0.2 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 PRP73653.1 - 0.00014 22.1 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 PRP73653.1 - 0.0017 18.7 0.0 0.036 14.4 0.0 2.4 1 1 1 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 EF-hand_1 PF00036.32 PRP73654.1 - 6.8e-29 97.2 10.8 7.6e-08 31.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PRP73654.1 - 8.4e-28 96.6 10.6 4.2e-14 52.7 2.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP73654.1 - 5e-26 88.4 9.9 9.2e-08 31.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PRP73654.1 - 1.4e-23 82.5 11.5 3.5e-12 46.0 1.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 PRP73654.1 - 1.7e-12 47.4 0.5 1e-05 25.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PRP73654.1 - 3.3e-12 45.3 9.3 2.2e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 EF hand Caleosin PF05042.13 PRP73654.1 - 3.5e-06 27.0 2.4 0.29 11.1 0.0 3.8 1 1 3 4 4 4 2 Caleosin related protein EF-hand_11 PF08976.11 PRP73654.1 - 7.9e-05 23.5 1.2 0.0015 19.3 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 PRP73654.1 - 0.00019 21.3 3.8 0.29 11.1 0.1 2.7 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PRP73654.1 - 0.0005 20.4 1.2 0.18 12.2 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 PRP73654.1 - 0.026 14.5 0.7 0.15 12.0 0.1 2.3 1 1 2 3 3 3 0 Tellurite resistance protein TerB EF-hand_14 PF17959.1 PRP73654.1 - 0.029 14.7 1.7 1.6 9.1 0.3 2.5 2 1 0 2 2 2 0 EF-hand domain DUF1403 PF07183.11 PRP73654.1 - 0.056 13.0 0.0 0.26 10.8 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1403) DUF1636 PF07845.11 PRP73654.1 - 0.056 13.9 0.0 6.2 7.3 0.0 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1636) DUF2666 PF10869.8 PRP73654.1 - 0.086 13.0 3.6 6.2 7.0 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) EF-hand_like PF09279.11 PRP73654.1 - 0.099 13.1 2.2 0.89 10.1 0.1 2.7 2 1 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like MgtE_N PF03448.17 PRP73654.1 - 0.14 12.8 2.5 0.31 11.7 0.4 2.3 1 1 1 2 2 2 0 MgtE intracellular N domain GPHH PF16905.5 PRP73654.1 - 0.15 11.8 0.0 1.5 8.7 0.0 2.4 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated DUF1002 PF06207.11 PRP73654.1 - 0.16 11.4 0.3 13 5.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1002) Toprim_2 PF13155.6 PRP73654.1 - 0.21 12.0 2.3 9.5 6.7 0.8 3.0 1 1 2 3 3 3 0 Toprim-like Pkinase PF00069.25 PRP73655.1 - 3.2e-23 82.5 0.0 3.6e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73655.1 - 2.5e-05 23.7 0.0 3.6e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase GDP_Man_Dehyd PF16363.5 PRP73660.1 - 1.6e-48 165.9 0.0 1.8e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PRP73660.1 - 1.9e-08 34.1 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Tricorn_PDZ PF14685.6 PRP73660.1 - 0.049 13.6 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain GXGXG PF01493.19 PRP73660.1 - 0.049 13.2 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 GXGXG motif FERM_F2 PF18377.1 PRP73661.1 - 0.046 13.7 0.5 0.058 13.3 0.4 1.3 1 1 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain RdRP_1 PF00680.20 PRP73662.1 - 0.12 10.9 0.2 0.15 10.6 0.2 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Colipase-like PF15083.6 PRP73663.1 - 0.041 14.0 9.1 0.077 13.1 9.1 1.4 1 0 0 1 1 1 0 Colipase-like Dynamin_M PF01031.20 PRP73664.1 - 0.0034 16.6 0.5 0.005 16.1 0.5 1.2 1 0 0 1 1 1 1 Dynamin central region CRISPR_Cas9_WED PF18061.1 PRP73664.1 - 0.045 13.8 0.7 0.19 11.8 0.3 2.0 1 1 0 2 2 2 0 CRISPR-Cas9 WED domain rve PF00665.26 PRP73666.1 - 8.3e-14 51.8 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain MliC PF09864.9 PRP73666.1 - 0.065 13.2 0.9 0.38 10.7 0.2 2.3 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Nramp PF01566.18 PRP73668.1 - 8.1e-52 176.4 7.4 2e-51 175.1 7.4 1.6 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein DUF4208 PF13907.6 PRP73669.1 - 0.016 15.7 1.5 0.02 15.3 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) RT_RNaseH_2 PF17919.1 PRP73670.1 - 4.9e-29 100.3 0.0 9.3e-29 99.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP73670.1 - 1.2e-21 77.2 0.7 2e-21 76.6 0.2 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 PRP73670.1 - 1.5e-20 73.4 0.0 3.1e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase tRNA_int_endo PF01974.17 PRP73671.1 - 0.0019 18.2 0.2 0.71 10.0 0.0 2.6 2 0 0 2 2 2 2 tRNA intron endonuclease, catalytic C-terminal domain Casein PF00363.18 PRP73671.1 - 0.0052 17.1 0.0 4.4 7.8 0.0 2.7 2 0 0 2 2 2 2 Casein Prolactin_RP PF15172.6 PRP73671.1 - 0.057 13.1 0.1 16 5.2 0.0 2.5 2 0 0 2 2 2 0 Prolactin-releasing peptide zf-met PF12874.7 PRP73671.1 - 0.057 13.8 0.5 20 5.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PilJ_C PF18223.1 PRP73671.1 - 0.44 11.1 3.2 24 5.5 0.1 3.1 3 0 0 3 3 3 0 Pili PilJ C-terminal domain DUF3143 PF11341.8 PRP73671.1 - 0.52 10.7 2.4 30 5.1 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) XRN_M PF17846.1 PRP73672.1 - 7.3 5.4 31.4 11 4.9 31.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Dimer_Tnp_hAT PF05699.14 PRP73673.1 - 6.6e-05 22.6 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 PRP73673.1 - 0.00094 19.5 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Integrase_H2C2 PF17921.1 PRP73675.1 - 2.2e-85 280.7 26.8 1.5e-21 76.2 1.1 5.0 4 0 0 4 4 4 4 Integrase zinc binding domain rve PF00665.26 PRP73675.1 - 2.8e-34 117.9 2.7 1.2e-15 57.8 0.1 4.1 3 0 0 3 3 3 2 Integrase core domain zf-H2C2 PF09337.10 PRP73675.1 - 2.3e-30 104.5 10.5 2.2e-06 27.8 0.1 4.6 4 0 0 4 4 4 4 H2C2 zinc finger RT_RNaseH PF17917.1 PRP73675.1 - 9.5e-25 86.9 0.3 8.2e-24 83.9 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP73675.1 - 8.3e-14 51.4 0.0 1.8e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo PF00385.24 PRP73675.1 - 3.4e-12 46.1 0.0 8.7e-12 44.8 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag_pre-integrs PF13976.6 PRP73675.1 - 1.8e-05 24.5 2.6 12 5.9 0.1 4.5 4 0 0 4 4 4 0 GAG-pre-integrase domain DUF4125 PF13526.6 PRP73675.1 - 0.0009 18.9 0.3 1.1 8.8 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF4125) Mhr1 PF12829.7 PRP73675.1 - 0.0012 18.9 4.4 38 4.5 0.1 4.8 4 0 0 4 4 4 0 Transcriptional regulation of mitochondrial recombination Ferrochelatase PF00762.19 PRP73675.1 - 0.0033 16.6 0.1 2.5 7.1 0.0 2.3 2 0 0 2 2 2 2 Ferrochelatase DUF261 PF03196.13 PRP73675.1 - 0.0034 17.5 2.4 33 4.6 0.0 4.3 5 0 0 5 5 4 0 Protein of unknown function, DUF261 DUF2543 PF10820.8 PRP73675.1 - 0.0064 16.6 2.8 4.2 7.6 0.2 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2543) BCS1_N PF08740.11 PRP73675.1 - 0.0093 16.0 0.5 3.2 7.7 0.1 3.3 3 0 0 3 3 3 1 BCS1 N terminal DUF918 PF06033.11 PRP73675.1 - 0.01 15.9 0.0 55 3.7 0.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF918) CbeA_antitoxin PF06154.11 PRP73675.1 - 0.071 13.7 0.0 3e+02 2.1 0.0 4.1 4 0 0 4 4 4 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A rve_3 PF13683.6 PRP73675.1 - 0.11 12.3 13.0 0.37 10.6 0.0 4.6 5 0 0 5 5 5 0 Integrase core domain WbqC PF08889.11 PRP73675.1 - 0.18 11.7 1.7 6.7 6.6 0.1 2.8 2 0 0 2 2 2 0 WbqC-like protein family Dmd PF17587.2 PRP73675.1 - 0.19 12.1 2.0 1.5 9.2 0.2 3.0 2 0 0 2 2 2 0 Discriminator of mRNA degradation FOXP-CC PF16159.5 PRP73675.1 - 0.62 10.7 3.8 71 4.1 0.0 4.5 5 0 0 5 5 5 0 FOXP coiled-coil domain MBOAT_2 PF13813.6 PRP73675.1 - 0.68 10.3 13.8 1.2 9.5 0.2 3.8 5 0 0 5 5 4 0 Membrane bound O-acyl transferase family HNH_2 PF13391.6 PRP73680.1 - 0.0086 16.2 0.0 0.042 14.0 0.0 2.2 1 1 0 1 1 1 1 HNH endonuclease MFS_1 PF07690.16 PRP73685.1 - 4.6e-11 42.2 8.9 6e-11 41.9 8.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PRP73685.1 - 0.00011 21.4 0.9 0.00013 21.1 0.9 1.2 1 0 0 1 1 1 1 Nucleoside H+ symporter MFS_1_like PF12832.7 PRP73685.1 - 0.0013 17.7 1.2 0.002 17.1 0.2 1.7 2 1 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 PRP73685.1 - 0.0018 16.9 3.3 0.0023 16.6 3.3 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 PRP73685.1 - 0.0046 15.9 5.0 0.0073 15.2 4.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Complex1_LYR PF05347.15 PRP73686.1 - 4.7e-09 36.2 2.1 8.8e-09 35.3 2.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PRP73686.1 - 0.00019 22.1 0.5 0.00022 21.9 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 PRP73686.1 - 0.024 15.2 0.5 0.035 14.7 0.5 1.3 1 1 0 1 1 1 0 Complex1_LYR-like Corona_5a PF06336.11 PRP73686.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Coronavirus 5a protein DUF4375 PF14300.6 PRP73687.1 - 0.035 14.4 0.5 1.1 9.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Pterin_4a PF01329.19 PRP73688.1 - 1.3e-10 41.2 1.2 2.9e-10 40.2 1.2 1.5 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Prefoldin_2 PF01920.20 PRP73689.1 - 1.6e-15 56.9 5.0 1.6e-15 56.9 5.0 1.9 2 0 0 2 2 2 1 Prefoldin subunit Rx_N PF18052.1 PRP73689.1 - 0.043 14.1 0.2 0.043 14.1 0.2 1.9 2 0 0 2 2 2 0 Rx N-terminal domain DUF948 PF06103.11 PRP73689.1 - 0.091 13.0 0.5 0.26 11.6 0.2 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) adh_short PF00106.25 PRP73690.1 - 1.4e-29 102.9 0.0 2.2e-29 102.3 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP73690.1 - 4.3e-21 75.6 0.0 5.2e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP73690.1 - 0.057 13.3 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 KR domain PH PF00169.29 PRP73691.1 - 0.00024 21.6 0.1 0.00063 20.2 0.1 1.9 1 1 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 PRP73691.1 - 0.0039 16.7 0.9 0.0071 15.8 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 PRP73691.1 - 0.0054 16.2 0.8 0.012 15.1 0.8 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 PRP73691.1 - 0.035 14.0 0.0 0.096 12.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 PRP73691.1 - 0.09 12.6 0.3 0.41 10.5 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 PRP73691.1 - 0.12 12.9 0.2 0.41 11.1 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair PH_11 PF15413.6 PRP73691.1 - 0.25 11.8 2.1 0.4 11.1 1.0 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain DUF1656 PF07869.12 PRP73692.1 - 0.092 12.8 0.4 0.15 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Ank_2 PF12796.7 PRP73693.1 - 2.7e-34 117.6 0.0 1.1e-08 35.5 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP73693.1 - 3.2e-21 75.4 2.5 1.3e-06 28.8 0.0 5.3 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP73693.1 - 2.4e-19 69.1 0.2 0.014 15.7 0.0 7.7 1 1 7 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP73693.1 - 6.6e-15 53.7 0.2 0.86 10.4 0.0 8.0 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 PRP73693.1 - 3.1e-14 52.7 1.6 1.4 9.5 0.1 8.3 6 2 2 8 8 8 3 Ankyrin repeat HTH_16 PF12645.7 PRP73693.1 - 2.2e-05 24.4 0.4 0.98 9.5 0.0 4.3 4 0 0 4 4 4 2 Helix-turn-helix domain DUF2939 PF11159.8 PRP73693.1 - 0.00013 22.3 1.0 0.17 12.3 0.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF2939) YlzJ PF14035.6 PRP73693.1 - 0.00069 19.8 0.1 37 4.6 0.0 5.3 6 1 0 6 6 6 0 YlzJ-like protein SBP_bac_11 PF13531.6 PRP73693.1 - 0.013 15.2 0.1 1.8 8.2 0.1 3.4 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein Sugar_tr PF00083.24 PRP73694.1 - 1.6e-07 30.5 1.0 2.4e-07 30.0 1.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter zf-C2H2_4 PF13894.6 PRP73694.1 - 0.033 15.0 4.1 0.39 11.7 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger GPS PF01825.21 PRP73695.1 - 1.6e-10 41.4 3.2 1.6e-10 41.4 3.2 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif B_lectin PF01453.24 PRP73695.1 - 0.014 16.0 0.3 0.034 14.7 0.3 1.6 1 0 0 1 1 1 0 D-mannose binding lectin UPF0560 PF10577.9 PRP73695.1 - 0.026 13.1 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Baculo_11_kDa PF06143.11 PRP73695.1 - 0.027 14.0 0.0 0.074 12.6 0.0 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Tad_C PF09977.9 PRP73695.1 - 0.097 13.9 0.1 0.35 12.1 0.1 1.9 1 0 0 1 1 1 0 Putative Tad-like Flp pilus-assembly Chlam_PMP PF02415.17 PRP73696.1 - 0.016 15.6 71.2 0.026 15.0 0.4 10.2 9 2 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF5123 PF17161.4 PRP73696.1 - 0.27 12.3 21.5 1.4 10.0 8.3 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF5123) LRR_8 PF13855.6 PRP73697.1 - 9e-19 67.0 36.6 7.1e-06 25.7 0.2 7.4 6 2 2 9 9 9 5 Leucine rich repeat LRR_4 PF12799.7 PRP73697.1 - 2.7e-12 46.7 57.3 0.0017 18.7 3.6 10.4 6 3 4 11 11 11 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP73697.1 - 1.5e-07 30.9 29.9 1.2 10.0 0.3 10.5 8 2 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP73697.1 - 0.0069 16.4 42.3 0.61 10.3 0.0 9.9 12 0 0 12 12 12 4 Leucine Rich repeat LRR_10 PF18805.1 PRP73697.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat DUF4246 PF14033.6 PRP73699.1 - 5.5e-120 401.5 0.7 6.9e-120 401.2 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RNA_pol_3_Rpc31 PF11705.8 PRP73699.1 - 0.0011 19.2 20.6 0.0031 17.8 20.6 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Adap_comp_sub PF00928.21 PRP73699.1 - 0.0025 17.3 0.1 0.0043 16.5 0.1 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF913 PF06025.12 PRP73699.1 - 0.0046 16.0 1.1 0.0072 15.4 1.1 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 PRP73699.1 - 0.036 12.2 33.1 0.076 11.1 31.8 1.9 2 0 0 2 2 2 0 DNA polymerase phi Vfa1 PF08432.10 PRP73699.1 - 0.049 14.0 9.4 0.093 13.1 9.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAPS PF04499.15 PRP73699.1 - 0.22 10.3 2.7 0.33 9.7 2.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 PRP73699.1 - 0.27 10.6 27.6 0.45 9.9 27.6 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 PRP73699.1 - 0.28 9.9 5.1 0.4 9.4 5.1 1.1 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 PRP73699.1 - 0.29 9.7 2.8 0.39 9.3 2.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Nop14 PF04147.12 PRP73699.1 - 0.31 9.2 28.5 0.46 8.7 28.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.6 PRP73699.1 - 0.46 10.0 2.2 0.74 9.4 2.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_pol_Rpc4 PF05132.14 PRP73699.1 - 0.49 10.8 6.6 0.93 9.9 6.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 BUD22 PF09073.10 PRP73699.1 - 0.54 9.5 21.8 0.86 8.9 21.8 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.8 PRP73699.1 - 1.4 7.6 10.3 2.9 6.6 10.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Drc1-Sld2 PF11719.8 PRP73699.1 - 2.9 7.3 16.1 4.8 6.6 16.1 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Mpp10 PF04006.12 PRP73699.1 - 2.9 6.2 28.7 0.54 8.6 25.2 1.4 2 0 0 2 2 2 0 Mpp10 protein DUF4746 PF15928.5 PRP73699.1 - 3.3 7.1 20.0 6.3 6.1 20.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 PRP73699.1 - 6.6 4.9 22.1 9.7 4.3 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 PRP73699.1 - 6.6 6.5 16.0 12 5.6 16.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 PRP73699.1 - 9.3 4.9 9.2 14 4.3 9.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF-3c_N PF05470.12 PRP73699.1 - 9.7 4.4 10.9 13 3.9 10.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus LRRFIP PF09738.9 PRP73701.1 - 0.016 14.7 0.2 0.016 14.7 0.2 1.0 1 0 0 1 1 1 0 LRRFIP family Gly_transf_sug PF04488.15 PRP73702.1 - 0.00019 22.0 0.2 0.00057 20.5 0.2 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PRP73702.1 - 0.0041 16.5 1.6 0.0061 16.0 1.6 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DUF4575 PF15143.6 PRP73705.1 - 0.11 12.7 0.1 0.15 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4575) AMMECR1 PF01871.17 PRP73706.1 - 6.3e-42 143.0 0.0 8.1e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 HOOK PF05622.12 PRP73707.1 - 0.00021 19.6 13.9 0.00026 19.3 13.9 1.2 1 0 0 1 1 1 1 HOOK protein FUSC PF04632.12 PRP73707.1 - 0.0003 19.5 1.9 0.00038 19.2 1.9 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family bZIP_1 PF00170.21 PRP73707.1 - 0.017 15.2 1.0 0.017 15.2 1.0 2.9 3 0 0 3 3 3 0 bZIP transcription factor DUF1515 PF07439.11 PRP73707.1 - 0.15 12.1 0.2 0.46 10.5 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF1664 PF07889.12 PRP73707.1 - 0.15 12.1 8.4 0.038 14.0 3.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF728 PF05304.12 PRP73707.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Cauli_AT PF03233.13 PRP73707.1 - 0.21 11.5 7.3 0.18 11.7 0.7 2.5 1 1 1 2 2 2 0 Aphid transmission protein Shugoshin_N PF07558.11 PRP73707.1 - 0.28 11.1 4.7 0.2 11.6 1.9 2.3 2 0 0 2 2 1 0 Shugoshin N-terminal coiled-coil region Laminin_II PF06009.12 PRP73707.1 - 0.43 10.6 10.1 0.27 11.2 5.9 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF4559 PF15112.6 PRP73707.1 - 0.5 10.0 10.7 0.13 12.0 5.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Syntaxin_2 PF14523.6 PRP73707.1 - 1 9.7 13.9 0.073 13.4 2.9 3.0 1 1 0 2 2 2 0 Syntaxin-like protein DASH_Dam1 PF08653.10 PRP73707.1 - 1.1 9.1 2.9 31 4.5 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Occludin_ELL PF07303.13 PRP73707.1 - 1.3 9.8 9.7 0.57 10.9 3.8 3.1 2 1 2 4 4 3 0 Occludin homology domain BST2 PF16716.5 PRP73707.1 - 1.4 9.5 14.3 0.067 13.8 2.7 2.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF745 PF05335.13 PRP73707.1 - 2.3 7.9 10.9 4.8 6.9 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DegQ PF08181.11 PRP73707.1 - 2.3 8.4 7.1 5.1 7.3 0.3 2.7 3 0 0 3 3 2 0 DegQ (SacQ) family WSD PF15613.6 PRP73707.1 - 6 7.4 8.7 0.93 10.0 3.8 2.4 3 1 0 3 3 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif TMPIT PF07851.13 PRP73707.1 - 7.8 5.6 8.0 3.7 6.7 5.7 1.7 1 1 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.9 PRP73707.1 - 9.9 6.9 9.7 1.6e+02 3.0 9.1 2.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) tRNA-synt_2_TM PF16995.5 PRP73708.1 - 0.016 14.9 0.3 0.02 14.6 0.3 1.4 1 1 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase DUF3784 PF12650.7 PRP73708.1 - 0.14 12.4 1.5 0.19 12.0 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Zn_clus PF00172.18 PRP73709.1 - 0.064 13.4 1.3 0.12 12.5 1.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pentapeptide_4 PF13599.6 PRP73710.1 - 0.00019 21.5 4.2 0.0094 16.1 0.6 3.1 3 1 1 4 4 4 2 Pentapeptide repeats (9 copies) Pkinase_Tyr PF07714.17 PRP73711.1 - 3.9e-71 239.4 0.0 6.2e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP73711.1 - 5.7e-47 160.3 0.0 8.6e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP73711.1 - 1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PA PF02225.22 PRP73711.1 - 1.2e-05 25.2 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 PA domain Haspin_kinase PF12330.8 PRP73711.1 - 0.00043 19.3 0.0 0.0025 16.8 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain LRR_8 PF13855.6 PRP73711.1 - 0.0018 18.0 13.8 0.036 13.8 0.5 4.8 3 2 1 4 4 4 2 Leucine rich repeat APH PF01636.23 PRP73711.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 PRP73711.1 - 0.084 12.5 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Ac110_PIF PF07280.11 PRP73711.1 - 0.12 12.2 1.6 0.33 10.7 1.6 1.8 1 0 0 1 1 1 0 Per os infectivity factor AC110 EphA2_TM PF14575.6 PRP73711.1 - 0.14 13.0 0.1 0.31 11.9 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pkinase_fungal PF17667.1 PRP73711.1 - 0.17 10.6 0.2 0.35 9.6 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase LRR_1 PF00560.33 PRP73711.1 - 0.6 10.9 18.2 1.7e+02 3.4 0.0 9.0 8 1 0 8 8 7 0 Leucine Rich Repeat Kdo PF06293.14 PRP73711.1 - 0.88 8.9 2.7 0.3 10.4 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.7 PRP73711.1 - 1.1 9.8 28.9 2.7 8.6 0.1 7.0 7 1 0 7 7 7 0 Leucine Rich repeats (2 copies) P16-Arc PF04699.14 PRP73712.1 - 0.14 12.6 0.0 0.17 12.3 0.0 1.0 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) OrfB_Zn_ribbon PF07282.11 PRP73714.1 - 0.0026 17.6 0.2 0.0042 17.0 0.2 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain RNA_pol_Rpb8 PF03870.15 PRP73714.1 - 0.046 13.9 0.3 0.056 13.6 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb8 MRP-S26 PF14943.6 PRP73714.1 - 0.8 9.6 8.0 1.1 9.1 8.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 XLF PF09302.11 PRP73714.1 - 1.1 9.4 5.4 0.36 11.0 0.8 2.0 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component rve PF00665.26 PRP73716.1 - 2.6e-13 50.2 0.0 5.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 PRP73716.1 - 4e-12 45.9 0.0 1.1e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SO_alpha_A3 PF17806.1 PRP73721.1 - 0.12 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain DUF4286 PF14114.6 PRP73722.1 - 0.021 15.3 0.6 0.064 13.7 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) rve PF00665.26 PRP73723.1 - 3e-21 75.8 0.0 5e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PRP73723.1 - 0.074 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain AIF_C PF14721.6 PRP73725.1 - 0.0082 16.5 2.5 0.036 14.4 2.5 1.9 1 1 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Erp_C PF06780.11 PRP73725.1 - 0.016 15.3 0.2 0.018 15.0 0.2 1.1 1 0 0 1 1 1 0 Erp protein C-terminus DUF4034 PF13226.6 PRP73727.1 - 0.066 12.6 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) DUF4034 PF13226.6 PRP73729.1 - 0.013 14.8 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) SpmSyn_N PF17950.1 PRP73729.1 - 0.027 14.6 4.0 0.31 11.3 0.2 3.2 1 1 2 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal Sp38 PF07354.12 PRP73729.1 - 0.087 12.2 0.7 0.14 11.5 0.7 1.4 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) MHB PF16525.5 PRP73729.1 - 0.25 11.6 2.9 5.5 7.3 1.4 3.4 3 0 0 3 3 3 0 Haemophore, haem-binding MRP-S26 PF14943.6 PRP73729.1 - 0.45 10.4 16.7 0.34 10.8 11.6 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 GvpL_GvpF PF06386.11 PRP73729.1 - 0.48 10.3 3.6 1 9.2 1.9 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DNA_pol_B_2 PF03175.13 PRP73730.1 - 7.6e-08 31.7 7.7 4.7e-07 29.0 2.4 2.2 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral Imm30 PF15565.6 PRP73730.1 - 0.0023 18.0 0.0 0.011 15.8 0.0 2.0 1 1 1 2 2 2 1 Immunity protein 30 PMP1_2 PF08114.11 PRP73731.1 - 0.02 14.7 0.2 0.058 13.2 0.2 1.7 1 0 0 1 1 1 0 ATPase proteolipid family Peptidase_S58 PF03576.14 PRP73731.1 - 0.028 14.0 0.1 0.041 13.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase family S58 Gelsolin PF00626.22 PRP73732.1 - 3.4e-21 74.9 0.1 3.4e-09 36.5 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat VHP PF02209.19 PRP73732.1 - 2.8e-14 52.9 1.2 2.8e-14 52.9 1.2 2.1 2 0 0 2 2 2 1 Villin headpiece domain Macoilin PF09726.9 PRP73733.1 - 7.5 5.0 8.1 13 4.2 8.1 1.3 1 0 0 1 1 1 0 Macoilin family BST2 PF16716.5 PRP73734.1 - 0.018 15.6 0.2 0.019 15.6 0.2 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 NADH_Oxid_Nqo15 PF11497.8 PRP73734.1 - 0.11 12.5 0.1 0.12 12.4 0.1 1.0 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 Dynamitin PF04912.14 PRP73734.1 - 0.17 11.2 3.2 0.18 11.1 3.2 1.0 1 0 0 1 1 1 0 Dynamitin Linker_histone PF00538.19 PRP73735.1 - 0.00093 19.5 0.6 6.2 7.3 0.0 3.8 2 1 1 3 3 3 2 linker histone H1 and H5 family KfrA_N PF11740.8 PRP73735.1 - 0.11 13.2 5.2 1.3 9.7 0.0 3.4 3 1 1 4 4 4 0 Plasmid replication region DNA-binding N-term Imm49 PF15575.6 PRP73735.1 - 0.13 12.0 1.4 0.57 9.9 0.2 2.3 2 0 0 2 2 2 0 Immunity protein 49 S1-P1_nuclease PF02265.16 PRP73735.1 - 2.7 7.7 7.3 0.1 12.4 0.9 1.8 3 0 0 3 3 3 0 S1/P1 Nuclease MRP-S26 PF14943.6 PRP73735.1 - 7.8 6.4 19.0 0.32 10.9 9.8 2.7 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S26 Guanylin PF02058.15 PRP73735.1 - 9.7 6.7 12.1 3.4 8.2 0.8 3.4 3 0 0 3 3 3 0 Guanylin precursor rve PF00665.26 PRP73737.1 - 1.1e-09 38.5 0.0 1.3e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain PHAT PF09246.10 PRP73737.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.3 1 1 0 1 1 1 0 PHAT TFB6 PF17110.5 PRP73737.1 - 0.18 11.5 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_B_2 PF03175.13 PRP73738.1 - 1.1e-13 50.9 1.0 2.1e-13 49.9 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral p31comet PF06581.12 PRP73739.1 - 0.1 11.7 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Menin PF05053.13 PRP73742.1 - 0.78 8.0 2.1 1.2 7.4 2.1 1.1 1 0 0 1 1 1 0 Menin LRR_8 PF13855.6 PRP73743.1 - 3.4e-30 103.6 52.3 1.6e-09 37.4 8.3 4.7 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 PRP73743.1 - 3.9e-21 74.8 29.7 1.5e-06 28.4 5.8 6.4 3 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP73743.1 - 1.1e-06 28.3 25.7 4.2 8.3 0.0 9.4 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 PRP73743.1 - 0.15 12.2 37.0 2.8 8.2 0.4 8.5 9 0 0 9 9 9 0 Leucine Rich repeat TNFR_16_TM PF18422.1 PRP73744.1 - 0.3 11.1 2.7 0.75 9.8 2.7 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF1765 PF08578.10 PRP73745.1 - 0.00013 22.4 0.7 0.0002 21.8 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Serpin PF00079.20 PRP73746.1 - 1.5e-52 179.2 0.0 2.8e-52 178.3 0.0 1.4 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF155 PF02582.14 PRP73746.1 - 2.9e-40 138.2 2.1 1.5e-39 135.9 0.6 2.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 RRM_1 PF00076.22 PRP73746.1 - 5.6e-18 64.5 0.0 1.6e-17 63.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP73746.1 - 0.0021 18.1 0.0 0.0085 16.2 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif Csm1_B PF18211.1 PRP73746.1 - 0.14 12.0 0.0 30 4.5 0.0 2.6 2 0 0 2 2 2 0 Csm1 subunit domain B Clathrin_H_link PF13838.6 PRP73751.1 - 0.092 12.7 0.7 0.17 11.8 0.7 1.4 1 0 0 1 1 1 0 Clathrin-H-link YgaB PF14182.6 PRP73753.1 - 0.058 13.8 0.2 0.22 11.9 0.0 2.0 2 0 0 2 2 2 0 YgaB-like protein HPP PF04982.13 PRP73754.1 - 1.1e-29 103.0 9.0 1.6e-29 102.5 9.0 1.2 1 0 0 1 1 1 1 HPP family RPOL_N PF14700.6 PRP73754.1 - 0.023 14.1 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal PHO4 PF01384.20 PRP73754.1 - 0.062 12.3 4.5 0.088 11.8 4.5 1.2 1 0 0 1 1 1 0 Phosphate transporter family DUF1770 PF08589.10 PRP73754.1 - 0.17 12.9 1.6 0.28 12.2 1.6 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Connexin PF00029.19 PRP73754.1 - 0.8 9.4 2.0 1.2 8.9 2.0 1.2 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 PRP73754.1 - 1.8 8.2 4.4 3.2 7.4 4.4 1.3 1 0 0 1 1 1 0 FAM176 family SAP PF02037.27 PRP73759.1 - 3.4e-07 29.9 0.1 8.6e-07 28.6 0.1 1.7 1 0 0 1 1 1 1 SAP domain DUF2790 PF10976.8 PRP73760.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) Chromo PF00385.24 PRP73761.1 - 8.7e-14 51.2 0.0 1.1e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 PRP73761.1 - 0.015 15.2 0.2 0.027 14.3 0.2 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain SAWADEE PF16719.5 PRP73761.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 SAWADEE domain Mob_synth_C PF06463.13 PRP73762.1 - 2.2e-40 137.5 0.0 4.3e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 PRP73762.1 - 2.6e-31 109.2 1.0 8.5e-31 107.6 0.2 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.6 PRP73762.1 - 1.9e-08 34.7 0.1 7.7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 PRP73762.1 - 1.5e-05 25.1 0.1 0.00021 21.4 0.0 2.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Pkinase PF00069.25 PRP73763.1 - 2.2e-25 89.6 0.0 2.3e-12 46.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PRP73763.1 - 3.4e-06 26.6 0.0 0.01 15.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PRP73763.1 - 0.00052 19.4 0.5 0.23 10.8 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 PRP73763.1 - 0.016 14.8 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 APH PF01636.23 PRP73763.1 - 0.029 14.3 2.4 0.45 10.4 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF3993 PF13158.6 PRP73763.1 - 0.055 13.7 0.0 20 5.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3993) Seadorna_VP7 PF07387.11 PRP73763.1 - 0.11 11.5 1.9 3.2 6.7 0.1 2.5 2 0 0 2 2 2 0 Seadornavirus VP7 rve PF00665.26 PRP73764.1 - 3.6e-11 43.3 0.0 6.1e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF5542 PF17696.1 PRP73764.1 - 0.042 14.0 0.8 0.13 12.4 0.8 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF997 PF06196.12 PRP73766.1 - 0.0019 18.2 0.3 0.0046 16.9 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF997) ATG19_autophagy PF12744.7 PRP73767.1 - 0.05 12.8 0.0 9.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein Atg19, Atg8-binding TfuA PF07812.12 PRP73767.1 - 0.079 12.7 0.0 18 5.1 0.0 2.4 2 0 0 2 2 2 0 TfuA-like protein YceD PF02620.17 PRP73767.1 - 0.084 13.0 0.1 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Large ribosomal RNA subunit accumulation protein YceD DUF1799 PF08809.11 PRP73767.1 - 0.15 12.3 0.1 30 4.9 0.0 2.4 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) zf-RING_5 PF14634.6 PRP73767.1 - 0.48 10.4 8.3 5.6 7.0 1.1 2.5 2 0 0 2 2 2 0 zinc-RING finger domain C9orf72-like PF15019.6 PRP73768.1 - 0.0023 17.5 1.0 0.0045 16.6 1.0 1.5 1 0 0 1 1 1 1 C9orf72-like protein family UpxZ PF06603.11 PRP73768.1 - 0.022 15.1 2.4 0.087 13.1 0.1 2.9 3 0 0 3 3 3 0 UpxZ family of transcription anti-terminator antagonists X8 PF07983.13 PRP73769.1 - 1.6e-17 63.9 19.6 2e-09 38.0 6.0 3.2 3 1 0 3 3 3 2 X8 domain Glyco_hydro_17 PF00332.18 PRP73769.1 - 2.1e-06 27.5 0.2 2.4e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 zf-CHY PF05495.12 PRP73769.1 - 1 9.9 8.9 0.47 11.0 1.9 2.4 2 0 0 2 2 2 0 CHY zinc finger Peptidase_M20 PF01546.28 PRP73771.1 - 3.2e-25 89.1 0.0 3.8e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PRP73771.1 - 1.6e-11 44.0 0.0 3.8e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 PRP73771.1 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M16_C PF05193.21 PRP73772.1 - 4.6e-13 49.6 0.1 1.4e-12 48.0 0.1 1.9 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF3726 PF12525.8 PRP73774.1 - 0.053 13.6 0.0 0.065 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) RVT_1 PF00078.27 PRP73775.1 - 3.3e-25 88.9 0.0 5e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MPM1 PF17234.2 PRP73778.1 - 0.022 15.0 12.2 0.15 12.3 0.8 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 I_LWEQ PF01608.17 PRP73778.1 - 0.023 15.0 6.1 0.039 14.2 1.5 2.2 2 0 0 2 2 2 0 I/LWEQ domain MHB PF16525.5 PRP73778.1 - 0.11 12.7 1.3 2.4 8.5 1.0 2.7 2 0 0 2 2 2 0 Haemophore, haem-binding Paz_1 PF18349.1 PRP73778.1 - 0.17 11.8 1.4 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 PAZ domain CRISPR_Cas9_WED PF18061.1 PRP73778.1 - 4.1 7.5 11.9 0.53 10.4 0.7 3.2 2 2 0 3 3 3 0 CRISPR-Cas9 WED domain VitD-bind_III PF09164.10 PRP73780.1 - 0.12 12.4 3.1 0.62 10.1 0.1 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III MliC PF09864.9 PRP73781.1 - 0.046 13.7 0.2 0.054 13.5 0.2 1.1 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme DUF3644 PF12358.8 PRP73782.1 - 0.022 15.2 1.0 0.043 14.3 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3644) Bac_rhodopsin PF01036.18 PRP73783.1 - 2.8e-16 59.8 14.0 3.4e-16 59.5 14.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PalH PF08733.10 PRP73783.1 - 1.9 7.4 10.9 0.14 11.1 1.1 2.1 1 1 1 2 2 2 0 PalH/RIM21 Cupin_8 PF13621.6 PRP73784.1 - 9.2e-48 163.2 0.1 1.2e-47 162.8 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PRP73784.1 - 1.8e-08 34.2 0.0 1.7e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PRP73784.1 - 8.7e-05 22.9 0.1 0.00018 21.9 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 PRP73784.1 - 0.033 13.9 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Hydrolase_4 PF12146.8 PRP73785.1 - 3.1e-53 180.5 0.0 3.6e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP73785.1 - 7.1e-15 55.3 0.1 2e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP73785.1 - 3.7e-08 34.2 0.0 4.8e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 PRP73785.1 - 4.2e-05 23.8 0.0 0.00015 22.0 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.20 PRP73785.1 - 7.8e-05 22.4 0.0 9.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 PRP73785.1 - 0.0017 18.2 0.0 5.7 6.7 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 PRP73785.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 PRP73785.1 - 0.0067 15.9 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF915 PF06028.11 PRP73785.1 - 0.0098 15.2 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 PRP73785.1 - 0.011 15.4 0.0 0.077 12.6 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 PRP73785.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.13 PRP73785.1 - 0.079 11.5 0.1 0.29 9.6 0.1 1.7 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 PRP73785.1 - 0.084 12.6 0.3 0.55 10.0 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 PRP73785.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 PRP73785.1 - 0.13 11.2 0.0 0.68 8.8 0.0 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 PRP73785.1 - 0.16 11.5 0.0 6.6 6.2 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family UQ_con PF00179.26 PRP73786.1 - 1.3e-14 54.0 0.0 1.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CAF1A PF12253.8 PRP73788.1 - 8.7e-24 83.5 10.2 8.7e-24 83.5 10.2 4.2 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Pkinase_Tyr PF07714.17 PRP73789.1 - 2.1e-42 145.2 0.0 3.4e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP73789.1 - 3.5e-37 128.2 0.0 6.2e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FYVE PF01363.21 PRP73789.1 - 0.00038 20.6 2.6 0.013 15.6 2.6 2.4 1 1 0 1 1 1 1 FYVE zinc finger PH PF00169.29 PRP73789.1 - 0.0014 19.1 0.3 0.0025 18.3 0.3 1.4 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 PRP73789.1 - 0.0029 17.8 0.2 0.0083 16.3 0.2 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger Kinase-like PF14531.6 PRP73789.1 - 0.0068 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LAMTOR5 PF16672.5 PRP73792.1 - 3.1e-16 59.1 0.1 5.4e-16 58.3 0.1 1.4 1 1 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 PRP73792.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain Ank_2 PF12796.7 PRP73794.1 - 4.2e-25 88.1 1.7 2.5e-06 28.0 0.0 5.1 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP73794.1 - 8.7e-17 61.0 3.3 0.0012 19.1 0.0 7.5 3 1 5 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP73794.1 - 1.6e-14 54.0 2.0 2e-05 25.1 0.0 6.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP73794.1 - 2.3e-14 52.1 1.7 1.2 9.9 0.0 8.7 8 1 1 9 9 9 3 Ankyrin repeat Ank PF00023.30 PRP73794.1 - 1.6e-08 34.6 4.2 0.28 11.7 0.2 8.2 6 2 1 7 7 7 1 Ankyrin repeat F-box-like PF12937.7 PRP73794.1 - 0.0061 16.4 0.4 0.045 13.7 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 PRP73794.1 - 0.0077 16.1 0.0 0.0077 16.1 0.0 2.6 3 0 0 3 3 3 1 F-box domain SRPRB PF09439.10 PRP73794.1 - 0.019 14.4 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit rve PF00665.26 PRP73796.1 - 2.1e-19 69.8 0.0 1e-18 67.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain DUF4297 PF14130.6 PRP73796.1 - 0.045 13.9 1.3 14 5.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4297) DUF5463 PF17551.2 PRP73798.1 - 0.028 14.3 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5463) CAP PF00188.26 PRP73799.1 - 0.0018 19.1 0.3 5.5 7.8 0.0 3.1 3 0 0 3 3 3 2 Cysteine-rich secretory protein family GATase_2 PF00310.21 PRP73799.1 - 0.062 12.0 0.0 9.6 4.8 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferases class-II DUF601 PF04642.12 PRP73799.1 - 0.27 10.7 1.7 0.82 9.1 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Cyclin_C PF02984.19 PRP73800.1 - 0.0083 16.2 2.6 2.8 8.1 0.1 3.2 3 0 0 3 3 3 2 Cyclin, C-terminal domain NtA PF03146.15 PRP73800.1 - 0.06 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Agrin NtA domain Pkinase PF00069.25 PRP73801.1 - 1.1e-07 31.5 0.1 1.9e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-U1 PF06220.12 PRP73802.1 - 2.6e-20 71.9 4.2 3.8e-20 71.4 4.2 1.3 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 PRP73802.1 - 0.0097 15.8 1.5 0.016 15.1 1.5 1.4 1 0 0 1 1 1 1 CLIP1 zinc knuckle Bromodomain PF00439.25 PRP73804.1 - 4.6e-14 52.2 0.1 1.1e-13 51.1 0.1 1.7 1 0 0 1 1 1 1 Bromodomain SAP PF02037.27 PRP73804.1 - 3.2e-09 36.3 0.6 5.7e-09 35.5 0.6 1.5 1 0 0 1 1 1 1 SAP domain zf-RVT PF13966.6 PRP73806.1 - 0.0024 18.6 1.6 0.003 18.2 0.8 1.6 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RecR PF02132.15 PRP73806.1 - 1.9 8.1 4.6 0.29 10.7 0.6 1.7 2 0 0 2 2 2 0 RecR protein DDE_3 PF13358.6 PRP73809.1 - 0.00062 19.5 0.0 0.0012 18.6 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease Nexin_C PF08628.12 PRP73811.1 - 0.32 11.6 2.2 0.9 10.1 0.1 2.4 2 0 0 2 2 2 0 Sorting nexin C terminal CK2S PF15011.6 PRP73815.1 - 0.0088 15.9 0.1 0.016 15.1 0.1 1.4 1 1 0 1 1 1 1 Casein Kinase 2 substrate DIOX_N PF14226.6 PRP73816.1 - 1.2e-30 106.7 0.0 2e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PRP73816.1 - 4.1e-20 72.2 0.0 7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4874 PF16173.5 PRP73818.1 - 1.5e-10 41.0 0.0 2.9e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4874) DUF4832 PF16116.5 PRP73818.1 - 0.0017 18.3 0.7 0.0034 17.3 0.7 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4832) Exo_endo_phos PF03372.23 PRP73819.1 - 1.3e-13 51.0 0.3 2.2e-13 50.3 0.3 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PRP73819.1 - 0.0078 16.1 0.0 0.045 13.6 0.0 2.1 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RSN1_7TM PF02714.15 PRP73820.1 - 3.4e-55 187.3 22.6 3.4e-55 187.3 22.6 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 PRP73820.1 - 1.5e-19 70.9 0.0 2.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 PRP73820.1 - 3.2e-18 66.0 5.3 3.2e-18 66.0 5.3 3.4 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport MFS_1 PF07690.16 PRP73821.1 - 5.4e-24 84.8 29.2 8.5e-14 51.2 16.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 PRP73821.1 - 4.4e-16 59.1 1.4 4.4e-16 59.1 1.4 2.1 2 1 0 2 2 2 1 Nodulin-like TetR_C_23 PF17931.1 PRP73821.1 - 0.16 12.1 0.1 0.29 11.2 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RasGEF PF00617.19 PRP73822.1 - 1.6e-43 148.9 8.3 2.5e-24 86.4 1.4 2.7 2 0 0 2 2 2 2 RasGEF domain Pkinase PF00069.25 PRP73822.1 - 4.3e-25 88.6 0.0 3e-24 85.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73822.1 - 9.7e-18 64.4 0.0 4.6e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP73822.1 - 3e-08 32.9 0.0 6.3e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RhoGAP PF00620.27 PRP73822.1 - 1.4e-07 31.5 0.0 1.2e-06 28.4 0.0 2.6 3 0 0 3 3 3 1 RhoGAP domain Kdo PF06293.14 PRP73822.1 - 0.00086 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RasGEF_N PF00618.20 PRP73822.1 - 0.003 17.8 6.4 0.21 11.9 0.1 4.5 4 1 0 4 4 4 1 RasGEF N-terminal motif APH PF01636.23 PRP73822.1 - 0.0078 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family BCDHK_Adom3 PF10436.9 PRP73822.1 - 0.041 13.7 0.2 4.5 7.1 0.0 2.8 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DNA_pol_E_B PF04042.16 PRP73823.1 - 7.6e-26 90.8 0.3 1.4e-25 89.9 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PPTA PF01239.22 PRP73823.1 - 4.7e-14 51.6 18.7 2.3e-05 23.9 0.9 5.4 4 0 0 4 4 4 3 Protein prenyltransferase alpha subunit repeat Pol_alpha_B_N PF08418.10 PRP73823.1 - 7.6e-10 39.2 7.1 1.1e-09 38.6 7.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Flavin_Reduct PF01613.18 PRP73823.1 - 0.038 14.0 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Flavin reductase like domain DUF3712 PF12505.8 PRP73824.1 - 7.8e-83 274.9 51.0 9.9e-14 51.7 0.2 9.3 10 0 0 10 10 10 7 Protein of unknown function (DUF3712) LEA_2 PF03168.13 PRP73824.1 - 0.83 10.2 21.9 35 5.0 0.1 9.7 12 0 0 12 12 12 0 Late embryogenesis abundant protein HNH_2 PF13391.6 PRP73829.1 - 2.5e-05 24.3 0.0 5.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease TPR_2 PF07719.17 PRP73829.1 - 0.00018 21.4 0.0 0.031 14.4 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP73829.1 - 0.019 14.8 0.0 0.11 12.4 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat FAP PF07174.11 PRP73829.1 - 4.3 6.7 20.8 6.6 6.1 20.8 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RRN3 PF05327.11 PRP73830.1 - 5.6e-91 305.8 7.5 1.7e-90 304.2 7.5 1.8 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 PPR_2 PF13041.6 PRP73830.1 - 4.8e-07 29.9 0.5 0.11 12.7 0.1 4.3 2 1 2 4 4 4 2 PPR repeat family PPR_3 PF13812.6 PRP73830.1 - 0.0045 17.0 1.8 0.19 11.8 0.1 3.1 2 1 1 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 PRP73830.1 - 1.4 9.3 11.1 19 5.8 0.1 4.9 5 0 0 5 5 5 0 PPR repeat MFS_1 PF07690.16 PRP73831.1 - 3.3e-32 111.8 31.5 2.6e-22 79.2 11.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Microcin PF03526.13 PRP73831.1 - 1.9 8.4 5.7 0.3 10.9 0.2 2.4 2 1 1 3 3 3 0 Colicin E1 (microcin) immunity protein DUF3464 PF11947.8 PRP73831.1 - 4.8 6.9 8.3 0.25 11.1 1.7 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 LETM1 PF07766.13 PRP73832.1 - 4e-77 259.2 5.4 1.7e-75 253.8 2.4 4.5 3 2 2 5 5 5 2 LETM1-like protein EF-hand_1 PF00036.32 PRP73832.1 - 9.4e-13 46.7 0.2 0.00044 19.6 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PRP73832.1 - 1.5e-11 43.9 0.6 2.8e-08 33.5 0.1 4.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP73832.1 - 5e-10 38.5 0.6 0.025 14.5 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PRP73832.1 - 6.7e-10 39.3 4.3 2.3e-08 34.4 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP73832.1 - 1.4e-09 37.0 2.2 0.0011 18.4 0.1 3.9 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 PRP73832.1 - 1e-05 25.8 1.1 1e-05 25.8 1.1 3.7 3 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region SAP PF02037.27 PRP73832.1 - 0.0021 17.8 0.6 0.0021 17.8 0.6 2.9 3 0 0 3 3 3 1 SAP domain DUF572 PF04502.13 PRP73833.1 - 5.2e-73 246.5 22.1 6.2e-73 246.3 22.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 PRP73833.1 - 0.057 13.4 0.8 7.2 6.6 0.1 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_4 PF13717.6 PRP73833.1 - 0.57 10.2 5.0 4.7 7.2 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain UQ_con PF00179.26 PRP73834.1 - 1e-45 154.8 0.0 1.2e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PRP73834.1 - 0.042 13.5 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 PRP73834.1 - 0.081 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 PRP73834.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 tRNA-synt_1 PF00133.22 PRP73835.1 - 2.8e-156 521.3 1.7 3.6e-156 520.9 1.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PRP73835.1 - 1.1e-23 83.7 3.8 8.3e-08 31.4 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PRP73835.1 - 6.4e-18 65.2 0.1 1.4e-17 64.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PRP73835.1 - 0.0045 16.4 0.0 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Takusan PF04822.13 PRP73835.1 - 0.0071 16.2 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Takusan Acetyltransf_15 PF17013.5 PRP73835.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase Synaptobrevin PF00957.21 PRP73836.1 - 0.0027 17.4 0.6 0.0091 15.8 0.6 1.9 1 0 0 1 1 1 1 Synaptobrevin Herpes_IE2_3 PF03361.14 PRP73836.1 - 0.08 12.8 3.9 1 9.2 0.7 2.2 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 Lipoprotein_6 PF01441.19 PRP73836.1 - 0.24 11.4 3.0 2.9 7.9 0.1 2.4 2 1 0 2 2 2 0 Lipoprotein DUF3316 PF11777.8 PRP73836.1 - 1.7 8.7 4.2 1 9.4 1.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3316) KIAA1430 PF13879.6 PRP73836.1 - 4.9 8.0 13.2 0.36 11.6 3.4 2.7 2 1 0 2 2 2 0 KIAA1430 homologue BRCT_3 PF18428.1 PRP73838.1 - 1.7e-11 44.1 2.5 3.4e-11 43.1 0.3 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 PRP73838.1 - 7.1e-09 35.9 0.2 2.7e-07 30.8 0.0 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP73838.1 - 0.00067 20.0 0.1 0.091 13.2 0.0 2.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Retrotran_gag_3 PF14244.6 PRP73839.1 - 0.17 11.7 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Ras PF00071.22 PRP73841.1 - 3.5e-58 195.8 0.0 4.1e-58 195.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP73841.1 - 1.7e-35 121.8 0.0 3.2e-35 120.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP73841.1 - 1.7e-14 53.7 0.0 1.9e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP73841.1 - 5.5e-05 22.6 0.0 6.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP73841.1 - 0.0002 21.0 0.0 0.00044 19.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATPase PF06745.13 PRP73841.1 - 0.0034 16.8 0.4 1.8 7.8 0.0 2.1 2 0 0 2 2 2 2 KaiC RsgA_GTPase PF03193.16 PRP73841.1 - 0.048 13.6 0.1 11 5.9 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase Glyco_transf_41 PF13844.6 PRP73842.1 - 2e-65 221.1 0.2 2.7e-35 121.7 0.4 2.2 1 1 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 PRP73842.1 - 0.00012 21.9 0.7 0.64 10.3 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP73842.1 - 0.00025 21.6 0.1 0.00048 20.7 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP73842.1 - 0.0043 17.7 1.2 0.68 10.9 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF4482 PF14818.6 PRP73842.1 - 3 8.7 8.8 0.61 10.9 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Methyltransf_5 PF01795.19 PRP73843.1 - 2.5e-52 178.3 0.0 3.9e-29 102.2 0.1 3.0 2 2 0 2 2 2 2 MraW methylase family Methyltransf_19 PF04672.12 PRP73843.1 - 0.025 14.1 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl methyltransferase HAD_SAK_2 PF18143.1 PRP73843.1 - 0.14 12.5 0.2 0.4 11.0 0.2 1.8 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Cpn10 PF00166.21 PRP73844.1 - 1.7e-25 88.9 0.1 1.9e-25 88.7 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Telomere_Sde2_2 PF13297.6 PRP73845.1 - 0.058 13.0 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Telomere stability C-terminal B5 PF03484.15 PRP73846.1 - 0.022 15.1 0.0 0.047 14.0 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetase B5 domain PhoQ_Sensor PF08918.10 PRP73846.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor GATA PF00320.27 PRP73848.1 - 1.3e-14 53.5 4.8 2.9e-14 52.3 4.8 1.6 1 0 0 1 1 1 1 GATA zinc finger TFIIE_alpha PF02002.17 PRP73849.1 - 5.1e-07 29.5 0.6 5.1e-07 29.5 0.6 3.4 3 1 0 3 3 3 1 TFIIE alpha subunit Zn_Tnp_IS1595 PF12760.7 PRP73849.1 - 0.0014 18.5 1.7 0.0025 17.7 0.5 2.0 2 0 0 2 2 2 1 Transposase zinc-ribbon domain TFIIE-A_C PF11521.8 PRP73849.1 - 0.0017 18.6 2.1 0.0017 18.6 2.1 2.4 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha PhnA_Zn_Ribbon PF08274.12 PRP73849.1 - 0.01 15.8 0.9 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-ACC PF17848.1 PRP73849.1 - 0.024 14.7 4.7 0.12 12.5 0.4 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain HTH_29 PF13551.6 PRP73849.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix TF_Zn_Ribbon PF08271.12 PRP73849.1 - 0.056 13.0 1.3 0.74 9.4 1.3 2.4 1 1 0 1 1 1 0 TFIIB zinc-binding C1_4 PF07975.12 PRP73849.1 - 0.67 10.2 3.2 4.6 7.5 0.2 2.6 1 1 1 2 2 2 0 TFIIH C1-like domain DUF2197 PF09963.9 PRP73849.1 - 0.77 10.1 3.8 3.2 8.1 3.8 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 PRP73849.1 - 2.6 7.7 4.2 23 4.7 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger WD40 PF00400.32 PRP73850.1 - 0.0045 17.8 0.1 0.012 16.4 0.0 1.7 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP73850.1 - 0.026 14.8 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP73851.1 - 1.8e-11 44.4 0.0 7.5e-05 23.4 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat eIF2A PF08662.11 PRP73851.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 PRP73851.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain CBP_BcsR PF10945.8 PRP73854.1 - 0.42 10.1 3.4 5.8 6.5 0.1 2.7 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR I_LWEQ PF01608.17 PRP73855.1 - 1.5e-52 177.9 201.9 4.4e-38 130.9 17.6 18.3 6 4 11 18 18 18 11 I/LWEQ domain VBS PF08913.10 PRP73855.1 - 0.00026 21.4 0.8 0.00026 21.4 0.8 12.8 11 3 3 14 14 14 3 Vinculin Binding Site Focal_AT PF03623.13 PRP73855.1 - 0.024 14.7 60.9 0.15 12.1 1.1 12.2 10 4 3 13 13 13 0 Focal adhesion targeting region Vac_Fusion PF02346.16 PRP73855.1 - 0.031 13.9 0.6 11 5.7 0.0 3.8 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 NPA PF16469.5 PRP73855.1 - 0.046 14.3 0.2 0.046 14.3 0.2 4.3 4 0 0 4 4 4 0 Nematode polyprotein allergen ABA-1 Pkinase PF00069.25 PRP73856.1 - 5.5e-30 104.6 0.2 8.2e-30 104.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73856.1 - 6e-29 101.1 0.2 9.2e-29 100.5 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP73856.1 - 0.0012 19.3 0.5 0.0044 17.5 0.5 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF5433 PF17498.2 PRP73856.1 - 0.03 14.5 0.1 6.7 7.0 0.0 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5433) F-box-like PF12937.7 PRP73857.1 - 8.2e-05 22.4 0.0 0.00043 20.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP73857.1 - 0.0019 18.0 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain MORN PF02493.20 PRP73858.1 - 3.5e-08 32.9 16.6 3.8e-05 23.3 2.1 3.2 3 0 0 3 3 3 2 MORN repeat PH PF00169.29 PRP73859.1 - 0.056 14.0 0.8 8.4 7.0 0.1 2.5 1 1 1 2 2 2 0 PH domain Zn_clus PF00172.18 PRP73860.1 - 0.028 14.5 2.9 0.056 13.6 2.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AGH PF17558.2 PRP73860.1 - 0.52 10.5 5.1 0.8 9.9 0.3 2.8 2 1 1 3 3 3 0 Androgenic gland hormone VWA_2 PF13519.6 PRP73861.1 - 0.0013 19.3 0.0 0.0019 18.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TssR PF17643.1 PRP73861.1 - 0.0066 14.5 0.0 0.0083 14.1 0.0 1.0 1 0 0 1 1 1 1 Type VI secretion system, TssR VWA PF00092.28 PRP73861.1 - 0.018 15.3 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain Integrin_beta PF00362.18 PRP73861.1 - 0.074 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Integrin beta chain VWA domain Ank_2 PF12796.7 PRP73867.1 - 1.2e-29 102.8 0.1 2.2e-10 40.9 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP73867.1 - 6.9e-17 61.6 3.7 0.0011 19.5 0.0 6.3 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP73867.1 - 4.4e-14 52.2 4.3 1.5 9.4 0.0 8.2 9 0 0 9 9 9 3 Ankyrin repeat Ank_3 PF13606.6 PRP73867.1 - 1.2e-11 43.8 7.2 0.67 10.7 0.0 8.2 9 0 0 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 PRP73867.1 - 1.4e-09 38.0 6.6 0.09 13.1 0.0 7.5 2 2 6 8 8 8 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 PRP73867.1 - 0.0014 18.6 0.2 0.024 14.6 0.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF3447) BLACT_WH PF17778.1 PRP73867.1 - 0.18 11.8 0.0 0.53 10.3 0.0 1.9 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain F-box-like PF12937.7 PRP73867.1 - 1 9.3 8.5 0.5 10.3 1.4 2.5 2 0 0 2 2 2 0 F-box-like MCLC PF05934.11 PRP73870.1 - 2.5 6.7 8.7 3.8 6.1 8.7 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF4637 PF15470.6 PRP73870.1 - 6.4 6.5 11.6 1.9 8.2 7.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) ALMT PF11744.8 PRP73870.1 - 8.9 5.0 8.6 14 4.3 8.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SAP PF02037.27 PRP73871.1 - 0.022 14.5 0.1 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 SAP domain Cellulase PF00150.18 PRP73872.1 - 6e-21 75.1 2.3 7.8e-21 74.7 2.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 PRP73872.1 - 8.5e-05 22.6 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) FtsK_4TM PF13491.6 PRP73873.1 - 0.012 15.3 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE Aldo_ket_red PF00248.21 PRP73874.1 - 1.9e-43 148.7 0.0 2.4e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3511 PF12023.8 PRP73874.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) Chitin_bind_1 PF00187.19 PRP73875.1 - 1.5e-07 31.8 22.6 2.8e-07 30.9 22.6 1.4 1 0 0 1 1 1 1 Chitin recognition protein KTI12 PF08433.10 PRP73880.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MRP-S26 PF14943.6 PRP73881.1 - 0.094 12.6 13.3 0.15 12.0 13.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 XkdW PF09636.10 PRP73881.1 - 0.63 10.2 9.1 0.81 9.8 4.9 2.2 1 1 1 2 2 2 0 XkdW protein Wx5_PLAF3D7 PF09688.10 PRP73881.1 - 2.7 8.0 14.4 2.5 8.1 8.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) eIF-4B PF06273.11 PRP73881.1 - 4.2 6.3 5.2 4.9 6.1 5.2 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Exonuc_VII_L PF02601.15 PRP73881.1 - 4.3 6.8 6.6 5.4 6.5 6.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rhomboid PF01694.22 PRP73882.1 - 2.3e-10 40.7 5.4 4.2e-10 39.8 5.4 1.4 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 PRP73882.1 - 3.4e-05 23.9 7.0 5.2e-05 23.3 3.2 2.2 2 0 0 2 2 2 1 Der1-like family DUF4534 PF15049.6 PRP73882.1 - 0.071 12.9 0.7 0.15 11.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) CRISPR_Cas9_WED PF18061.1 PRP73882.1 - 0.17 12.0 1.4 0.88 9.7 0.5 2.2 1 1 0 2 2 2 0 CRISPR-Cas9 WED domain RT_RNaseH PF17917.1 PRP73885.1 - 4.9e-50 168.2 0.0 5.2e-24 84.6 0.0 3.0 3 0 0 3 3 3 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP73885.1 - 3.2e-45 152.2 0.0 1.2e-24 86.3 0.0 2.8 3 0 0 3 3 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP73885.1 - 3.3e-19 69.3 0.1 6.3e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PRP73885.1 - 1.1e-15 57.9 0.0 2.3e-14 53.6 0.0 3.0 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.24 PRP73885.1 - 4.4e-11 42.5 0.4 9.6e-11 41.4 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 PRP73885.1 - 3.3e-08 33.5 0.0 1.5e-07 31.4 0.0 2.2 2 0 0 2 2 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PRP73885.1 - 2.8e-06 27.4 0.0 7.2e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Asp_protease_2 PF13650.6 PRP73885.1 - 1.1e-05 26.0 0.0 2.8e-05 24.7 0.0 1.8 2 0 0 2 2 1 1 Aspartyl protease Retrotrans_gag PF03732.17 PRP73885.1 - 8.7e-05 22.7 0.9 0.00029 21.0 0.0 2.4 3 0 0 3 3 3 1 Retrotransposon gag protein gag-asp_proteas PF13975.6 PRP73885.1 - 0.00031 21.2 0.0 0.00071 20.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Integrase_Zn PF02022.19 PRP73885.1 - 0.0025 17.7 0.5 0.0094 15.9 0.1 2.3 2 0 0 2 2 2 1 Integrase Zinc binding domain Asp_protease PF09668.10 PRP73885.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-C2H2_10 PF16588.5 PRP73885.1 - 0.2 11.4 1.2 0.46 10.2 1.2 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger C2-set_2 PF08205.12 PRP73888.1 - 0.034 14.2 0.1 0.094 12.8 0.1 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Vac14_Fab1_bd PF12755.7 PRP73888.1 - 0.079 13.6 0.2 0.71 10.5 0.0 2.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region YniB PF14002.6 PRP73888.1 - 1.3 8.7 3.8 1.9 8.2 0.2 2.5 3 0 0 3 3 3 0 YniB-like protein Paz_1 PF18349.1 PRP73891.1 - 0.00044 20.1 2.2 0.31 11.0 0.0 2.4 2 0 0 2 2 2 2 PAZ domain DUF3405 PF11885.8 PRP73891.1 - 0.0074 14.9 2.4 0.014 14.1 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) GH43_C2 PF17851.1 PRP73891.1 - 0.031 14.0 1.5 0.051 13.3 1.5 1.4 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain LCIB_C_CA PF18599.1 PRP73891.1 - 0.78 9.0 3.7 1.5 8.0 3.7 1.5 1 1 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF45 PF01863.17 PRP73891.1 - 6.9 6.6 11.9 0.51 10.4 4.0 2.4 2 1 1 3 3 3 0 Protein of unknown function DUF45 zf-RVT PF13966.6 PRP73893.1 - 0.017 15.8 1.1 0.026 15.2 0.8 1.7 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase Glycos_trans_3N PF02885.17 PRP73893.1 - 0.019 14.8 0.1 0.078 12.8 0.0 2.0 2 1 0 2 2 2 0 Glycosyl transferase family, helical bundle domain RE_NgoBV PF09564.10 PRP73893.1 - 0.052 13.0 0.0 1.1 8.7 0.0 2.0 1 1 1 2 2 2 0 NgoBV restriction endonuclease K_trans PF02705.16 PRP73893.1 - 0.27 9.7 0.1 0.36 9.3 0.1 1.1 1 0 0 1 1 1 0 K+ potassium transporter RNase_H PF00075.24 PRP73895.1 - 1e-05 25.8 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNase H B12-binding_2 PF02607.17 PRP73898.1 - 0.076 13.5 0.0 0.089 13.2 0.0 1.1 1 0 0 1 1 1 0 B12 binding domain DUF4020 PF13212.6 PRP73898.1 - 0.25 11.2 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) DUF3405 PF11885.8 PRP73902.1 - 0.00083 18.1 2.2 0.0009 18.0 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Prophage_tail PF06605.11 PRP73902.1 - 0.025 13.8 0.7 0.026 13.8 0.7 1.1 1 0 0 1 1 1 0 Prophage endopeptidase tail OrfB_Zn_ribbon PF07282.11 PRP73902.1 - 0.027 14.4 0.2 0.049 13.6 0.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Sp38 PF07354.12 PRP73902.1 - 0.057 12.9 0.4 0.07 12.6 0.4 1.3 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) MRP-S26 PF14943.6 PRP73902.1 - 0.091 12.7 12.5 0.12 12.2 12.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 LRRFIP PF09738.9 PRP73902.1 - 0.094 12.2 13.6 0.11 11.9 12.4 1.6 1 1 0 1 1 1 0 LRRFIP family Glyco_hydro_65m PF03632.15 PRP73902.1 - 0.26 10.1 3.2 0.28 10.0 3.2 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain DUF45 PF01863.17 PRP73902.1 - 0.31 11.1 7.5 0.45 10.5 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF45 EMC3_TMCO1 PF01956.16 PRP73902.1 - 5.9 6.6 7.7 7.7 6.2 7.7 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like TPR_1 PF00515.28 PRP73903.1 - 5.3e-06 26.0 1.0 0.011 15.5 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP73903.1 - 3.2e-05 23.7 0.5 2.5 8.4 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP73903.1 - 0.049 13.9 1.1 7.2 7.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.28 PRP73904.1 - 1.1e-35 124.0 0.1 1.5e-35 123.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 PRP73904.1 - 0.0034 17.1 0.0 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain SRP54 PF00448.22 PRP73905.1 - 8.8e-53 178.9 0.8 1.8e-52 177.9 0.8 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 PRP73905.1 - 4.7e-08 33.1 0.0 1.2e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 PRP73905.1 - 8.1e-05 23.1 0.0 0.00026 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 PRP73905.1 - 0.00014 21.9 1.4 0.0015 18.5 1.4 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 PRP73905.1 - 0.00021 21.2 0.3 0.019 14.9 0.3 2.4 1 1 0 1 1 1 1 NTPase AAA_30 PF13604.6 PRP73905.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP73905.1 - 0.0046 16.3 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 PRP73905.1 - 0.0059 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 PRP73905.1 - 0.007 15.4 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 PRP73905.1 - 0.0082 15.9 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP73905.1 - 0.016 15.4 0.1 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Thiamine_BP PF01910.17 PRP73905.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Thiamine-binding protein MMR_HSR1 PF01926.23 PRP73905.1 - 0.022 14.8 0.7 0.087 12.9 0.7 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Peripla_BP_4 PF13407.6 PRP73905.1 - 0.027 14.0 1.9 0.25 10.9 0.1 2.5 1 1 1 3 3 3 0 Periplasmic binding protein domain Fer4_NifH PF00142.18 PRP73905.1 - 0.037 13.5 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA PF00004.29 PRP73905.1 - 0.039 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Inhibitor_I78 PF11720.8 PRP73905.1 - 0.065 13.3 0.0 8.3 6.5 0.0 3.5 4 0 0 4 4 4 0 Peptidase inhibitor I78 family APS_kinase PF01583.20 PRP73905.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.17 PRP73905.1 - 0.068 12.8 0.0 0.24 11.1 0.0 1.9 1 1 0 1 1 1 0 Thymidylate kinase ATP_bind_1 PF03029.17 PRP73905.1 - 0.091 12.5 0.7 2.2 8.0 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein F-box-like PF12937.7 PRP73906.1 - 0.05 13.5 0.7 0.13 12.2 0.7 1.7 1 0 0 1 1 1 0 F-box-like LSM PF01423.22 PRP73907.1 - 5.3e-16 58.1 0.3 6.1e-16 57.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain HPS3_Mid PF14762.6 PRP73908.1 - 2.7e-19 69.2 0.7 1.9e-18 66.4 0.1 2.3 2 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3, middle region UPA PF17217.3 PRP73908.1 - 0.053 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 UPA domain SUR7 PF06687.12 PRP73908.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family HPS3_N PF14761.6 PRP73908.1 - 0.087 12.3 0.1 0.21 11.1 0.1 1.6 1 1 0 1 1 1 0 Hermansky-Pudlak syndrome 3 PHD PF00628.29 PRP73910.1 - 5.3e-08 32.6 11.7 9.7e-08 31.8 11.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 PRP73910.1 - 0.0035 17.6 2.3 0.0058 16.9 2.3 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 PRP73910.1 - 1.9 8.6 8.9 4.1 7.5 8.9 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PRP73910.1 - 5.9 7.1 10.6 24 5.2 10.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Kinesin PF00225.23 PRP73913.1 - 7.3e-109 363.7 0.3 1.1e-108 363.2 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 PRP73913.1 - 2e-28 99.8 10.2 1.6e-21 77.3 2.0 3.3 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 PRP73913.1 - 3.1e-25 88.8 0.0 9.5e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding FHA PF00498.26 PRP73913.1 - 1.3e-06 28.6 0.0 7.9e-05 22.9 0.0 3.2 3 0 0 3 3 3 1 FHA domain FmiP_Thoc5 PF09766.9 PRP73913.1 - 0.00054 19.4 0.8 0.0011 18.4 0.8 1.4 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 DUF4407 PF14362.6 PRP73913.1 - 0.57 9.5 3.8 0.3 10.4 1.0 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_trans_N PF14510.6 PRP73914.1 - 7.7e-09 36.0 0.1 1.7e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC_tran PF00005.27 PRP73914.1 - 5.5e-07 30.2 0.0 1.2e-06 29.1 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 PRP73914.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PI31_Prot_N PF11566.8 PRP73915.1 - 3.8e-33 114.6 0.0 4.8e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 PRP73915.1 - 3.8e-08 34.4 17.1 3.8e-08 34.4 17.1 2.6 3 0 0 3 3 3 1 PI31 proteasome regulator RT_RNaseH PF17917.1 PRP73916.1 - 2.1e-33 114.7 0.0 4.6e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP73916.1 - 5.7e-30 103.3 0.0 1.2e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP73916.1 - 2.1e-22 79.0 1.1 5.9e-22 77.5 1.1 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP73916.1 - 4.6e-15 55.8 0.1 1.1e-14 54.7 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 PRP73916.1 - 4.7e-07 29.9 0.1 9.3e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger MBOAT_2 PF13813.6 PRP73916.1 - 0.22 11.8 1.2 0.61 10.4 0.2 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family FragX_IP PF05994.11 PRP73917.1 - 1.9e-145 486.1 0.0 2.2e-145 485.9 0.0 1.0 1 0 0 1 1 1 1 Cytoplasmic Fragile-X interacting family COesterase PF00135.28 PRP73918.1 - 7e-87 292.4 0.1 8.4e-87 292.2 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP73918.1 - 4e-12 46.4 0.2 7.7e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP73918.1 - 0.00014 21.4 0.1 0.00023 20.7 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family RRM_1 PF00076.22 PRP73920.1 - 9.5e-14 51.0 0.1 1.8e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 PRP73920.1 - 0.0068 17.1 5.0 0.0068 17.1 5.0 3.3 3 1 0 3 3 3 1 Glycine rich protein family EF-hand_6 PF13405.6 PRP73921.1 - 0.023 14.6 0.6 10 6.4 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 PRP73921.1 - 0.045 13.3 1.9 4.5 7.0 0.1 2.4 2 0 0 2 2 2 0 EF hand B3 PF02362.21 PRP73924.1 - 0.043 13.7 0.2 0.18 11.7 0.0 2.1 3 0 0 3 3 3 0 B3 DNA binding domain RIF5_SNase_2 PF18189.1 PRP73927.1 - 0.039 13.8 0.1 0.045 13.5 0.1 1.1 1 0 0 1 1 1 0 TbRIF5 SNase domain 2 DALR_1 PF05746.15 PRP73928.1 - 0.015 15.5 0.4 8.8 6.5 0.0 2.8 2 0 0 2 2 2 0 DALR anticodon binding domain Sharpin_PH PF16764.5 PRP73928.1 - 0.026 14.3 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 Sharpin PH domain DUF1298 PF06974.13 PRP73928.1 - 0.12 12.3 0.4 0.68 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) UPF0231 PF06062.11 PRP73928.1 - 0.29 11.4 1.9 8.9 6.6 0.0 3.7 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0231) NYN PF01936.18 PRP73929.1 - 4.7e-12 46.6 0.0 9.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 NYN domain DUF5615 PF18480.1 PRP73929.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) ATP11 PF06644.11 PRP73930.1 - 3e-21 76.4 1.3 3.8e-21 76.1 1.3 1.2 1 0 0 1 1 1 1 ATP11 protein HAD_2 PF13419.6 PRP73931.1 - 7e-12 45.8 0.0 1.1e-11 45.2 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP73931.1 - 1.2e-07 32.2 0.0 9.6e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PRP73931.1 - 0.0032 17.9 0.0 0.004 17.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 PRP73931.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 1 0 1 1 1 0 Putative Phosphatase BSD PF03909.17 PRP73931.1 - 1.7 8.7 5.6 0.59 10.2 0.2 2.4 2 0 0 2 2 2 0 BSD domain SNF2_N PF00176.23 PRP73932.1 - 4.6e-62 209.8 0.6 9.5e-62 208.7 0.6 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 PRP73932.1 - 1.1e-34 118.9 1.5 1.1e-34 118.9 1.5 5.3 4 1 1 5 5 5 1 SLIDE Helicase_C PF00271.31 PRP73932.1 - 3.8e-19 69.1 0.1 3.5e-18 66.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP73932.1 - 1.4e-11 44.7 0.1 1.4e-11 44.7 0.1 5.6 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit HAND PF09110.11 PRP73932.1 - 2.5e-09 37.9 8.1 2.5e-09 37.9 8.1 8.2 3 3 2 5 5 5 1 HAND DBINO PF13892.6 PRP73932.1 - 1.2e-06 28.9 10.9 1.2e-06 28.9 10.9 8.8 4 2 3 7 7 7 1 DNA-binding domain DEAD PF00270.29 PRP73932.1 - 6.4e-06 26.1 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PRP73932.1 - 0.025 14.9 0.1 0.16 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain Acetyltransf_7 PF13508.7 PRP73933.1 - 4e-09 36.8 0.0 6.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP73933.1 - 1.5e-08 34.6 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP73933.1 - 5.5e-07 29.8 0.0 8.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PRP73933.1 - 0.00015 21.7 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PRP73933.1 - 0.00052 20.1 0.2 0.0015 18.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_80 PF13647.6 PRP73933.1 - 0.19 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 80 of chitosanase A SnoaL_2 PF12680.7 PRP73934.1 - 1e-05 26.1 0.0 1.3e-05 25.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 PRP73934.1 - 0.00031 21.1 0.0 0.00038 20.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) LEH PF07858.12 PRP73934.1 - 0.0019 18.3 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain SnoaL_4 PF13577.6 PRP73934.1 - 0.0053 16.9 0.0 0.0058 16.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 PRP73934.1 - 0.013 15.8 0.0 0.017 15.4 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.20 PRP73934.1 - 0.021 15.4 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain CAP59_mtransfer PF11735.8 PRP73935.1 - 3.4e-54 184.1 0.0 4.3e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 EGF_MSP1_1 PF12946.7 PRP73935.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 BTB_2 PF02214.22 PRP73936.1 - 4.2e-24 84.7 0.0 3.9e-23 81.6 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 PRP73936.1 - 2.7e-10 40.3 0.0 9.6e-10 38.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Fis1_TPR_C PF14853.6 PRP73936.1 - 0.033 14.3 0.1 0.061 13.4 0.1 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat BTB PF00651.31 PRP73936.1 - 0.085 13.1 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain Abhydrolase_6 PF12697.7 PRP73937.1 - 2.2e-19 71.0 0.2 2.6e-19 70.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP73937.1 - 3.8e-19 69.3 0.0 7.4e-19 68.4 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP73937.1 - 2e-15 56.7 0.0 3e-15 56.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 PRP73937.1 - 0.00021 21.6 0.2 0.00037 20.8 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Chlorophyllase PF07224.11 PRP73937.1 - 0.00028 20.0 0.0 0.00059 18.9 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase Thioesterase PF00975.20 PRP73937.1 - 0.00059 20.0 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 PRP73937.1 - 0.057 12.3 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 PRP73937.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein DUF676 PF05057.14 PRP73937.1 - 0.064 12.8 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 PRP73937.1 - 0.085 12.7 0.0 0.37 10.6 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_2 PF01674.18 PRP73937.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_2 PF02230.16 PRP73937.1 - 0.15 11.9 0.0 18 5.0 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF5010 PF16402.5 PRP73937.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) Scramblase PF03803.15 PRP73938.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Scramblase HC2 PF07382.11 PRP73939.1 - 6.6e-07 29.6 0.0 0.0015 18.6 0.0 2.3 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 Carb_bind PF10645.9 PRP73939.1 - 9.9e-06 25.7 65.5 0.00022 21.4 3.3 6.6 4 2 2 6 6 6 4 Carbohydrate binding DUF3605 PF12239.8 PRP73940.1 - 1.2e-16 61.4 0.1 7.1e-16 58.9 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) MRP-S34 PF16053.5 PRP73941.1 - 1.7e-10 40.6 0.0 2.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Snf7 PF03357.21 PRP73942.1 - 1e-40 139.1 30.9 1.9e-40 138.3 26.9 2.0 1 1 1 2 2 2 2 Snf7 Osmo_CC PF08946.10 PRP73942.1 - 0.0044 17.2 1.7 0.0044 17.2 1.7 2.2 2 0 0 2 2 2 1 Osmosensory transporter coiled coil DUF2533 PF10752.9 PRP73942.1 - 1.6 9.2 13.6 0.059 13.8 2.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2533) Glyco_hydro_16 PF00722.21 PRP73943.1 - 7.8e-46 155.8 7.2 1.1e-22 80.3 1.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 PRP73943.1 - 5.6e-09 36.3 23.4 1.7e-08 34.8 23.4 1.8 1 0 0 1 1 1 1 Chitin recognition protein COMM_domain PF07258.14 PRP73943.1 - 0.0015 18.6 0.4 2.4 8.4 0.0 2.3 2 0 0 2 2 2 2 COMM domain MBOAT_2 PF13813.6 PRP73944.1 - 1.1e-09 38.4 3.8 2.9e-09 37.1 3.8 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DB_JBP1 PF18526.1 PRP73944.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Thymine dioxygenase JBP1 DNA-binding domain BCS1_N PF08740.11 PRP73945.1 - 2.3e-43 148.4 0.6 3.1e-43 147.9 0.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 PRP73945.1 - 2.8e-15 56.9 0.0 4.7e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 PRP73945.1 - 0.00046 19.4 0.0 0.00073 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 PRP73945.1 - 0.0022 18.0 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PRP73945.1 - 0.0057 16.2 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 PRP73945.1 - 0.009 16.4 0.1 0.051 13.9 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain PPV_E1_C PF00519.17 PRP73945.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase AAA_25 PF13481.6 PRP73945.1 - 0.025 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PRP73945.1 - 0.034 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PRP73945.1 - 0.041 13.8 0.2 0.87 9.5 0.0 2.3 1 1 1 2 2 2 0 RsgA GTPase AAA_PrkA PF08298.11 PRP73945.1 - 0.041 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain RNA_helicase PF00910.22 PRP73945.1 - 0.047 14.1 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 1 0 RNA helicase RuvB_N PF05496.12 PRP73945.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 PRP73945.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Gcd10p PF04189.13 PRP73946.1 - 2e-56 191.3 0.1 2.5e-56 191.0 0.1 1.1 1 0 0 1 1 1 1 Gcd10p family LCAT PF02450.15 PRP73947.1 - 3.2e-54 184.6 0.0 2.6e-51 175.0 0.0 2.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ank_4 PF13637.6 PRP73947.1 - 7.4e-27 93.4 6.0 2.7e-11 43.8 0.2 4.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP73947.1 - 2.8e-21 75.3 2.4 9.9e-13 48.0 1.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP73947.1 - 1.9e-20 73.2 2.4 2e-11 44.3 1.2 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP73947.1 - 1e-18 65.4 0.2 3.3e-06 27.0 0.1 5.5 6 0 0 6 6 5 3 Ankyrin repeat Ank PF00023.30 PRP73947.1 - 1.2e-13 50.9 1.6 3.2e-05 24.2 0.3 4.6 4 0 0 4 4 4 3 Ankyrin repeat Lipase_2 PF01674.18 PRP73947.1 - 0.00012 21.7 0.0 0.0042 16.6 0.0 2.6 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_1 PF00561.20 PRP73947.1 - 0.00048 19.9 0.0 0.11 12.1 0.0 2.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.12 PRP73947.1 - 0.00088 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 PRP73947.1 - 0.0014 18.2 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 PRP73947.1 - 0.086 12.5 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein DUF4746 PF15928.5 PRP73948.1 - 0.21 11.0 6.5 0.25 10.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ANAPC15 PF15243.6 PRP73948.1 - 0.91 10.0 19.2 2.4 8.6 19.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 15 Methyltransf_16 PF10294.9 PRP73949.1 - 2.1e-41 141.6 0.0 3.4e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 PRP73949.1 - 1.6e-06 27.7 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PRP73949.1 - 2e-06 27.7 0.0 3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP73949.1 - 0.00041 21.0 0.0 0.00076 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP73949.1 - 0.00061 19.4 0.0 0.0009 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PRP73949.1 - 0.0062 16.4 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain A_deaminase PF00962.22 PRP73949.1 - 0.013 14.9 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Adenosine/AMP deaminase Methyltransf_11 PF08241.12 PRP73949.1 - 0.014 16.0 0.0 0.032 14.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 PRP73949.1 - 0.017 15.9 0.3 0.037 14.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MIF4G PF02854.19 PRP73950.1 - 1.2e-36 126.4 9.9 2.5e-36 125.3 9.9 1.6 1 0 0 1 1 1 1 MIF4G domain W2 PF02020.18 PRP73950.1 - 0.00039 20.5 0.0 0.0017 18.4 0.0 2.2 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon eIF_4G1 PF12152.8 PRP73950.1 - 0.0035 17.5 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.17 PRP73950.1 - 0.033 14.2 4.1 0.21 11.6 0.0 3.2 4 0 0 4 4 4 0 MA3 domain F-actin_cap_A PF01267.17 PRP73951.1 - 3.2e-86 289.1 0.0 3.6e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Retinal PF15449.6 PRP73952.1 - 4.2e-06 24.9 34.3 5.6e-06 24.5 34.3 1.1 1 0 0 1 1 1 1 Retinal protein cwf21 PF08312.12 PRP73952.1 - 0.00013 22.1 10.3 0.00013 22.1 10.3 3.8 3 1 0 3 3 3 1 cwf21 domain DUF3384 PF11864.8 PRP73953.1 - 1.5e-64 218.7 2.8 6.3e-64 216.6 1.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 PRP73953.1 - 1.6e-48 164.7 0.4 3e-39 134.5 0.1 2.7 2 0 0 2 2 2 2 Rap/ran-GAP MMS19_N PF14500.6 PRP73953.1 - 0.089 12.4 0.1 14 5.1 0.0 2.9 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Ank_3 PF13606.6 PRP73954.1 - 4.2e-07 29.8 0.3 2.1 9.2 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PRP73954.1 - 0.0013 19.0 0.1 4.6 7.7 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP73954.1 - 0.0037 17.8 0.0 14 6.4 0.0 4.5 5 1 1 6 6 6 1 Ankyrin repeats (many copies) F-box_4 PF15966.5 PRP73954.1 - 0.015 15.1 0.3 0.087 12.7 0.1 2.5 2 0 0 2 2 2 0 F-box F-box PF00646.33 PRP73954.1 - 0.026 14.4 0.7 0.026 14.4 0.7 2.3 2 0 0 2 2 2 0 F-box domain Xpo1 PF08389.12 PRP73955.1 - 2.6e-36 124.9 0.9 2.6e-36 124.9 0.9 3.2 5 0 0 5 5 5 1 Exportin 1-like protein UPF0149 PF03695.13 PRP73955.1 - 0.073 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) HSP70 PF00012.20 PRP73956.1 - 2.9e-207 689.6 8.4 3.5e-207 689.3 8.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP73956.1 - 1.6e-16 60.1 0.2 1.3e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 PRP73956.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 PRP73956.1 - 0.049 13.1 0.2 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 PRP73956.1 - 0.2 12.1 0.4 17 5.9 0.0 3.0 3 1 0 3 3 3 0 Cell division protein FtsA Cytochrom_B562 PF07361.11 PRP73956.1 - 0.76 10.5 5.4 14 6.4 0.3 2.7 2 0 0 2 2 2 0 Cytochrome b562 Ank_3 PF13606.6 PRP73957.1 - 0.00014 22.0 1.0 2.8 8.8 0.0 6.7 9 1 1 10 10 10 1 Ankyrin repeat Ank_4 PF13637.6 PRP73957.1 - 0.0028 18.2 3.2 1.7 9.3 0.0 5.7 4 3 2 6 6 6 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP73957.1 - 0.003 18.1 0.0 0.89 10.2 0.0 3.6 3 2 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP73957.1 - 0.0058 16.9 0.1 1.5e+02 2.8 0.0 5.1 3 1 2 5 5 5 0 Ankyrin repeats (many copies) DUF3134 PF11332.8 PRP73957.1 - 0.6 10.5 5.9 62 4.0 0.2 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3134) F-box-like PF12937.7 PRP73958.1 - 0.0019 18.1 0.5 0.0047 16.8 0.5 1.6 1 0 0 1 1 1 1 F-box-like YihI PF04220.12 PRP73958.1 - 0.0081 15.9 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 1 Der GTPase activator (YihI) Secretin_N PF03958.17 PRP73959.1 - 0.051 14.0 0.2 0.36 11.3 0.0 2.4 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain VWA_2 PF13519.6 PRP73960.1 - 1.8e-05 25.4 0.0 0.00019 22.0 0.0 2.3 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 PRP73960.1 - 2e-05 24.9 0.2 5.4e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Copine PF07002.16 PRP73960.1 - 0.00022 20.8 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 Copine VWA_3 PF13768.6 PRP73960.1 - 0.00038 20.4 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PRP73960.1 - 0.0028 17.1 0.3 0.058 12.8 0.3 2.2 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein EF-G-binding_N PF07299.11 PRP73960.1 - 0.083 13.4 0.5 0.59 10.7 0.4 2.4 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal FixH PF05751.11 PRP73960.1 - 0.1 12.6 0.0 0.1 12.6 0.0 1.6 2 0 0 2 2 2 0 FixH MWFE PF15879.5 PRP73960.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit Pro_isomerase PF00160.21 PRP73961.1 - 6.8e-47 159.7 0.1 7.6e-47 159.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rad9 PF04139.13 PRP73962.1 - 7.1e-67 225.5 6.7 8.5e-67 225.2 6.7 1.1 1 0 0 1 1 1 1 Rad9 PCNA_N PF00705.18 PRP73962.1 - 2.5e-05 24.0 0.3 6.1e-05 22.7 0.3 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Phyto_Pns9_10 PF05878.11 PRP73962.1 - 0.004 16.3 0.8 0.0062 15.7 0.8 1.2 1 0 0 1 1 1 1 Phytoreovirus nonstructural protein Pns9/Pns10 Hus1 PF04005.12 PRP73962.1 - 0.006 15.7 0.9 0.01 15.0 0.9 1.4 1 1 0 1 1 1 1 Hus1-like protein WD40 PF00400.32 PRP73963.1 - 2.5e-11 43.9 23.8 0.016 16.0 0.8 7.9 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP73963.1 - 5.5e-07 29.8 0.1 0.024 15.0 0.0 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BAAT_C PF08840.11 PRP73964.1 - 1.6 8.6 4.8 1.7 8.5 4.8 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DNA_pol3_a_NII PF11490.8 PRP73964.1 - 4.2 7.3 17.8 3.2 7.7 16.4 1.5 1 1 0 1 1 1 0 DNA polymerase III polC-type N-terminus II HSP70 PF00012.20 PRP73965.1 - 2.4e-207 689.8 6.7 2.9e-207 689.6 6.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP73965.1 - 2.3e-16 59.5 0.1 7.9e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 PRP73965.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF2387 PF09526.10 PRP73968.1 - 0.032 14.4 0.2 0.048 13.8 0.2 1.3 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1 PF03811.13 PRP73968.1 - 0.082 12.6 0.3 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 InsA N-terminal domain Pkinase PF00069.25 PRP73969.1 - 1.1e-69 234.8 0.1 1.9e-69 234.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP73969.1 - 3.3e-34 118.3 0.0 5.9e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c PF02518.26 PRP73969.1 - 7.1e-27 94.1 0.4 2.9e-26 92.2 0.4 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FHA PF00498.26 PRP73969.1 - 1.6e-15 57.2 0.1 3.8e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 FHA domain HisKA PF00512.25 PRP73969.1 - 6.5e-13 48.5 0.6 1.9e-12 47.0 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain MASE3 PF17159.4 PRP73969.1 - 8.8e-13 48.4 25.9 1.6e-12 47.6 25.9 1.4 1 0 0 1 1 1 1 Membrane-associated sensor domain Response_reg PF00072.24 PRP73969.1 - 6.7e-09 35.9 0.8 0.007 16.5 0.0 3.2 3 0 0 3 3 3 2 Response regulator receiver domain Kinase-like PF14531.6 PRP73969.1 - 2.2e-08 33.8 0.0 1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 PRP73969.1 - 0.0011 19.3 0.0 0.0037 17.5 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 PRP73969.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 PRP73969.1 - 0.0034 17.6 0.0 0.53 10.5 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 PRP73969.1 - 0.014 15.7 1.9 0.22 11.8 0.3 3.9 4 1 0 4 4 4 0 PAS domain PAS PF00989.25 PRP73969.1 - 0.46 10.5 3.8 0.53 10.3 0.0 3.1 4 0 0 4 4 4 0 PAS fold Ank_2 PF12796.7 PRP73970.1 - 9.7e-25 87.0 0.2 5.9e-10 39.6 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP73970.1 - 4.6e-16 59.0 0.2 3e-05 24.5 0.0 5.9 1 1 6 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP73970.1 - 2.2e-11 43.7 0.1 0.033 14.7 0.0 7.1 5 2 2 7 7 7 2 Ankyrin repeat Ank_3 PF13606.6 PRP73970.1 - 1.1e-08 34.6 0.1 0.56 10.9 0.0 6.1 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 PRP73970.1 - 5e-08 33.1 0.1 7.8 7.0 0.0 6.2 2 1 5 7 7 7 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 PRP73970.1 - 0.05 13.5 7.3 52 3.8 0.0 5.8 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain SET PF00856.28 PRP73971.1 - 3.8e-20 73.0 0.8 3.8e-20 73.0 0.8 3.8 2 2 0 2 2 2 1 SET domain Borrelia_P83 PF05262.11 PRP73971.1 - 1.9 6.9 30.1 2.9 6.3 30.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase_Tyr PF07714.17 PRP73972.1 - 5.2e-21 75.1 1.7 9.3e-21 74.3 1.7 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP73972.1 - 5.5e-17 61.6 55.3 0.00022 21.5 3.5 8.2 4 3 2 7 7 7 7 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP73972.1 - 8e-16 58.2 0.7 1.3e-15 57.5 0.7 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP73972.1 - 2.5e-14 52.8 54.7 2.4e-05 24.0 2.2 7.3 6 2 0 8 8 8 4 Leucine rich repeat GPS PF01825.21 PRP73972.1 - 5.9e-10 39.5 3.4 5.9e-10 39.5 3.4 2.1 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_9 PF14580.6 PRP73972.1 - 1.6e-05 24.5 14.1 0.0046 16.5 1.2 3.8 3 1 1 4 4 4 3 Leucine-rich repeat PRIMA1 PF16101.5 PRP73972.1 - 0.03 14.4 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LRR_1 PF00560.33 PRP73972.1 - 0.89 10.3 32.9 11 7.0 0.2 9.3 8 1 0 8 8 8 0 Leucine Rich Repeat JmjC PF02373.22 PRP73976.1 - 0.027 14.9 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF2406 PF10295.9 PRP73976.1 - 0.063 14.0 0.3 0.2 12.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) adh_short PF00106.25 PRP73976.1 - 0.25 10.8 0.2 9.5 5.6 0.2 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Thionin PF00321.17 PRP73977.1 - 1.1 9.8 3.0 0.63 10.6 0.3 2.0 2 0 0 2 2 2 0 Plant thionin V4R PF02830.18 PRP73978.1 - 1.6e-10 40.9 17.1 9.4e-09 35.2 0.3 3.3 3 0 0 3 3 3 2 V4R domain Holin_BhlA PF10960.8 PRP73978.1 - 0.023 14.6 0.3 0.053 13.5 0.3 1.6 1 0 0 1 1 1 0 BhlA holin family SpoIISB_antitox PF14185.6 PRP73978.1 - 0.05 13.5 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system HMG_CoA_synt_C PF08540.10 PRP73979.1 - 0.052 13.2 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal RNase_H PF00075.24 PRP73980.1 - 2.9e-05 24.3 0.0 6.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 RNase H Glft2_N PF17994.1 PRP73982.1 - 0.18 11.7 0.1 12 5.8 0.0 2.1 2 0 0 2 2 2 0 Galactofuranosyltransferase 2 N-terminal HNH_2 PF13391.6 PRP73987.1 - 0.028 14.5 0.0 0.13 12.5 0.0 2.4 1 1 0 1 1 1 0 HNH endonuclease MRP-S26 PF14943.6 PRP73987.1 - 0.17 11.8 7.1 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 rve PF00665.26 PRP73991.1 - 1.4e-07 31.7 0.0 2.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF2175 PF09943.9 PRP73991.1 - 0.081 13.2 0.4 0.2 11.9 0.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) RNase_H PF00075.24 PRP73995.1 - 8.8e-05 22.7 0.1 0.00046 20.4 0.0 2.1 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 PRP73995.1 - 0.0031 18.2 0.3 0.0078 16.9 0.3 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF716 PF04819.12 PRP73997.1 - 0.0049 16.5 0.4 0.0049 16.5 0.4 2.8 2 2 1 3 3 3 1 Family of unknown function (DUF716) Ytp1 PF10355.9 PRP73997.1 - 0.0064 15.7 0.3 0.015 14.5 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) MerC PF03203.14 PRP73997.1 - 3.6 8.1 11.5 0.63 10.5 4.3 2.9 2 1 1 3 3 3 0 MerC mercury resistance protein HMG_box_2 PF09011.10 PRP73998.1 - 0.00062 20.3 3.9 0.4 11.3 0.6 2.1 1 1 1 2 2 2 2 HMG-box domain RhoGEF PF00621.20 PRP74001.1 - 1e-09 38.9 2.2 3e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 PRP74001.1 - 2.5e-05 24.7 0.1 0.027 15.0 0.1 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 PRP74001.1 - 0.046 14.2 1.1 0.2 12.1 0.5 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain RNA_pol_Rpb1_5 PF04998.17 PRP74003.1 - 7e-17 61.7 0.7 5.2e-07 29.4 0.4 3.3 2 1 0 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 PRP74003.1 - 8.4e-08 32.3 0.0 0.0045 16.8 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 6 MRP-S32 PF10210.9 PRP74003.1 - 0.023 15.3 0.1 46 4.7 0.0 3.6 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S32 DUF5460 PF17544.2 PRP74003.1 - 0.038 13.0 0.1 5.1 6.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5460) RNA_pol_Rpb1_1 PF04997.12 PRP74004.1 - 2.1e-27 96.3 0.0 3.7e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 PRP74004.1 - 1.9e-16 60.4 0.0 4.1e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 TatD_DNase PF01026.21 PRP74004.1 - 1.1e-06 28.3 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase RNA_pol_Rpb1_2 PF00623.20 PRP74004.1 - 0.036 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Hydrolase_like PF13242.6 PRP74005.1 - 4.7e-21 74.6 0.0 5.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 PRP74005.1 - 2.5e-07 30.9 0.0 3.2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 PRP74005.1 - 0.021 14.5 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Pkinase_Tyr PF07714.17 PRP74006.1 - 8e-71 238.3 0.0 8.5e-70 235.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74006.1 - 9.8e-46 156.2 0.0 2.2e-45 155.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain ASL_C PF08328.11 PRP74006.1 - 0.013 15.6 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Complex1_LYR_2 PF13233.6 PRP74009.1 - 1.5e-13 51.3 3.1 2e-13 50.9 3.1 1.2 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 PRP74009.1 - 0.0089 16.1 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Arc_C PF18162.1 PRP74009.1 - 0.02 14.7 1.7 0.53 10.2 0.4 2.3 1 1 1 2 2 2 0 Arc C-lobe DUF3072 PF11272.8 PRP74009.1 - 0.057 13.3 0.7 1.5 8.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3072) BCAS2 PF05700.11 PRP74009.1 - 0.074 12.7 7.0 1.3 8.6 7.0 2.0 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF2680 PF10925.8 PRP74009.1 - 0.91 9.6 7.7 0.21 11.6 3.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Nup54_57_C PF18570.1 PRP74009.1 - 2.8 7.6 8.2 0.21 11.2 2.9 1.9 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain Syntaxin PF00804.25 PRP74010.1 - 0.0007 19.3 3.4 0.00094 18.9 2.9 1.4 1 1 0 1 1 1 1 Syntaxin SHE3 PF17078.5 PRP74010.1 - 0.002 17.9 3.0 0.0029 17.4 3.0 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 PRP74010.1 - 0.0071 15.3 6.8 0.011 14.7 6.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 PRP74010.1 - 0.014 14.5 5.3 0.025 13.6 5.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 PRP74010.1 - 0.014 15.6 12.5 0.02 15.1 11.6 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding HTH_Tnp_1 PF01527.20 PRP74010.1 - 0.032 14.5 2.2 1.7 9.1 0.5 2.7 2 1 0 2 2 2 0 Transposase DUF5069 PF16798.5 PRP74010.1 - 0.033 14.4 2.1 0.052 13.7 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) TSC22 PF01166.18 PRP74010.1 - 0.036 14.4 1.6 2.8 8.3 0.1 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family HetR_C PF18460.1 PRP74010.1 - 0.048 13.6 4.2 0.049 13.5 1.7 2.2 2 1 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain YabA PF06156.13 PRP74010.1 - 0.059 14.0 6.7 15 6.3 6.9 2.7 1 1 0 1 1 1 0 Initiation control protein YabA FapA PF03961.13 PRP74010.1 - 0.095 11.3 3.2 0.1 11.2 3.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TraC PF07820.12 PRP74010.1 - 0.16 12.3 0.5 0.16 12.3 0.5 2.2 2 0 0 2 2 2 0 TraC-like protein EzrA PF06160.12 PRP74010.1 - 0.21 9.7 10.0 0.47 8.6 10.0 1.4 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA bZIP_1 PF00170.21 PRP74010.1 - 0.36 11.0 8.8 8.4 6.6 0.2 3.4 2 1 1 3 3 3 0 bZIP transcription factor TolA_bind_tri PF16331.5 PRP74010.1 - 0.5 10.5 12.1 3.8 7.7 1.2 3.9 2 1 2 4 4 4 0 TolA binding protein trimerisation Fzo_mitofusin PF04799.13 PRP74010.1 - 0.65 9.5 4.6 6.5 6.3 1.1 2.2 1 1 1 2 2 2 0 fzo-like conserved region GTP-bdg_M PF16360.5 PRP74010.1 - 1.6 9.4 7.3 9 7.0 2.0 2.4 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region FlaC_arch PF05377.11 PRP74010.1 - 1.8 9.0 6.6 6.7 7.2 0.3 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.9 PRP74010.1 - 1.9 8.4 12.4 1.8 8.5 9.8 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain bZIP_2 PF07716.15 PRP74010.1 - 1.9 8.6 11.0 3.8 7.7 0.2 3.1 1 1 2 3 3 3 0 Basic region leucine zipper Csm1_N PF18504.1 PRP74010.1 - 3.1 8.2 10.9 1 9.8 0.9 3.1 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF5320 PF17253.2 PRP74010.1 - 3.3 8.8 6.7 20 6.3 0.9 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Spc24 PF08286.11 PRP74010.1 - 4.1 7.7 9.9 8 6.8 1.0 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 PRP74010.1 - 6.4 6.0 8.2 9.2 5.5 4.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 PRP74010.1 - 7.8 6.6 7.2 7.5 6.6 6.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4140 PF13600.6 PRP74010.1 - 8.7 6.9 8.5 6e+02 1.0 8.5 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.11 PRP74010.1 - 9.2 6.3 13.8 70 3.4 13.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 PRP74010.1 - 9.9 6.7 16.1 10 6.6 13.4 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region FCH PF00611.23 PRP74012.1 - 0.065 13.5 0.1 0.067 13.5 0.1 1.1 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1367 PF07105.11 PRP74012.1 - 0.15 11.7 0.0 0.15 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) zf-TRAF PF02176.18 PRP74013.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger RVT_1 PF00078.27 PRP74016.1 - 5.1e-14 52.3 0.1 7.6e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mob1_phocein PF03637.17 PRP74016.1 - 0.00082 19.4 0.2 0.0012 18.9 0.2 1.3 1 0 0 1 1 1 1 Mob1/phocein family DUF3784 PF12650.7 PRP74021.1 - 0.057 13.6 5.2 4.1 7.7 0.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) Microtub_bd PF16796.5 PRP74022.1 - 4.3e-05 23.5 0.0 4.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding HeH PF12949.7 PRP74023.1 - 0.0009 18.9 0.1 0.0022 17.6 0.1 1.7 1 1 1 2 2 2 1 HeH/LEM domain DUF1098 PF06497.11 PRP74023.1 - 0.091 13.2 0.1 0.18 12.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1098) Beta_helix PF13229.6 PRP74024.1 - 0.0006 19.7 13.6 0.00081 19.3 4.6 3.1 1 1 1 3 3 3 2 Right handed beta helix region NCD3G PF07562.14 PRP74024.1 - 0.0088 16.0 0.5 0.0088 16.0 0.5 2.5 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Chlam_PMP PF02415.17 PRP74024.1 - 0.31 11.6 1.6 2.5 8.7 0.2 3.1 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ephrin_rec_like PF07699.13 PRP74024.1 - 0.78 9.6 9.4 0.98 9.2 1.5 3.0 2 1 0 2 2 2 0 Putative ephrin-receptor like SAP PF02037.27 PRP74025.1 - 0.11 12.3 0.1 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 SAP domain Kinesin PF00225.23 PRP74026.1 - 1.2e-71 241.4 0.8 8.8e-52 176.1 0.3 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 PRP74026.1 - 6.2e-16 58.7 0.1 1.7e-15 57.2 0.1 1.7 1 1 0 1 1 1 1 Microtubule binding ELK PF03789.13 PRP74027.1 - 0.28 11.3 7.1 3.4 7.9 0.3 3.8 3 0 0 3 3 3 0 ELK domain FapA PF03961.13 PRP74027.1 - 2.1 6.9 17.2 3 6.3 17.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 PRP74027.1 - 2.1 7.8 6.2 3.4 7.1 6.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 PRP74027.1 - 5.4 4.8 16.4 7.9 4.3 16.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2884 PF11101.8 PRP74027.1 - 9.9 5.6 15.1 17 4.8 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Sortilin-Vps10 PF15902.5 PRP74030.1 - 4e-50 170.9 0.8 7e-50 170.1 0.0 1.6 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PRP74030.1 - 9.4e-31 107.4 5.2 1.4e-30 106.9 5.2 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 PRP74030.1 - 0.0025 17.6 0.3 0.92 9.8 0.1 3.4 2 0 0 2 2 2 1 BNR/Asp-box repeat Ureidogly_lyase PF04115.12 PRP74034.1 - 2.7e-47 161.0 0.0 5.4e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Ureidoglycolate lyase Abi_HHR PF07815.14 PRP74035.1 - 0.0052 16.9 0.1 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 Abl-interactor HHR SlyX PF04102.12 PRP74035.1 - 0.018 15.6 0.0 0.018 15.6 0.0 2.1 3 0 0 3 3 3 0 SlyX DUF2451 PF10474.9 PRP74035.1 - 0.025 14.4 0.4 0.033 14.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Tmemb_cc2 PF10267.9 PRP74035.1 - 0.077 12.1 0.3 0.1 11.7 0.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein FOXP-CC PF16159.5 PRP74035.1 - 1.7 9.3 3.6 1.5 9.5 1.8 1.8 1 1 1 2 2 2 0 FOXP coiled-coil domain Sec63 PF02889.16 PRP74036.1 - 6.8e-23 81.1 0.1 1e-22 80.6 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 PRP74036.1 - 8.2e-19 67.5 0.8 1.8e-18 66.4 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain FeoB_associated PF12669.7 PRP74036.1 - 0.021 15.2 3.8 0.1 13.0 1.0 2.7 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Chlor_dismutase PF06778.12 PRP74036.1 - 0.039 13.5 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 Chlorite dismutase Tetraspanin PF00335.20 PRP74036.1 - 0.12 12.0 3.9 0.55 9.9 0.2 3.0 3 0 0 3 3 3 0 Tetraspanin family EphA2_TM PF14575.6 PRP74036.1 - 0.18 12.7 0.7 11 6.9 0.0 3.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3586 PF12131.8 PRP74038.1 - 0.042 14.1 3.9 0.042 14.1 3.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) N6-adenineMlase PF10237.9 PRP74040.1 - 8.4e-41 139.4 0.4 9.9e-41 139.2 0.4 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase MTS PF05175.14 PRP74040.1 - 0.051 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain IF-2B PF01008.17 PRP74041.1 - 8.8e-74 248.2 0.0 1e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Elf4 PF07011.11 PRP74043.1 - 0.014 15.3 0.8 0.032 14.2 0.8 1.6 1 0 0 1 1 1 0 Early Flowering 4 domain DUF3987 PF13148.6 PRP74043.1 - 0.43 9.5 4.3 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Cellulase PF00150.18 PRP74047.1 - 4.2e-20 72.3 16.0 1.7e-18 67.1 9.3 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Chitin_bind_1 PF00187.19 PRP74047.1 - 3.7e-07 30.5 24.7 3.7e-07 30.5 24.7 2.1 2 0 0 2 2 2 1 Chitin recognition protein GRP PF07172.11 PRP74047.1 - 4.4 8.1 15.1 1.3 9.7 6.8 2.9 2 0 0 2 2 2 0 Glycine rich protein family Cellulase PF00150.18 PRP74048.1 - 3.6e-18 66.0 9.2 5e-18 65.5 9.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chitin_bind_1 PF00187.19 PRP74048.1 - 1.7e-06 28.4 22.6 6e-06 26.6 22.6 2.0 1 0 0 1 1 1 1 Chitin recognition protein Cellulase PF00150.18 PRP74049.1 - 3.8e-19 69.2 10.8 5.4e-19 68.7 10.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chitin_bind_1 PF00187.19 PRP74049.1 - 5.1e-07 30.1 23.1 1.5e-06 28.5 23.1 1.8 1 0 0 1 1 1 1 Chitin recognition protein DUF4434 PF14488.6 PRP74049.1 - 0.014 15.5 0.1 0.03 14.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) Cellulase PF00150.18 PRP74050.1 - 1.6e-18 67.2 9.4 2.3e-18 66.6 9.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAN_4 PF14295.6 PRP74050.1 - 2e-08 34.0 6.8 2e-08 34.0 6.8 2.2 2 0 0 2 2 2 1 PAN domain Chitin_bind_1 PF00187.19 PRP74050.1 - 4e-06 27.2 25.0 4e-06 27.2 25.0 2.7 2 0 0 2 2 2 1 Chitin recognition protein DUF4434 PF14488.6 PRP74050.1 - 0.077 13.0 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) LPD28 PF18843.1 PRP74050.1 - 0.2 11.3 0.0 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 28 Cellulase PF00150.18 PRP74051.1 - 3.4e-19 69.4 6.5 4.9e-19 68.8 6.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chitin_bind_1 PF00187.19 PRP74051.1 - 1.6e-08 34.9 21.6 1.6e-08 34.9 21.6 2.8 2 0 0 2 2 2 1 Chitin recognition protein PAN_4 PF14295.6 PRP74051.1 - 7.1e-07 29.0 6.0 7.1e-07 29.0 6.0 2.9 2 1 0 2 2 2 1 PAN domain DUF4434 PF14488.6 PRP74051.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) GST_C_6 PF17171.4 PRP74052.1 - 1.1e-17 63.5 0.2 5.3e-17 61.4 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 PRP74052.1 - 2.7e-10 40.6 0.0 5.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 PRP74052.1 - 7.8e-08 33.0 0.0 1.4e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 PRP74052.1 - 0.0001 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP74052.1 - 0.023 14.9 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP74052.1 - 0.034 14.3 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Aida_C2 PF14186.6 PRP74053.1 - 3.6e-52 175.9 0.2 1.2e-51 174.2 0.0 1.7 2 0 0 2 2 2 1 Cytoskeletal adhesion Aida_N PF08910.10 PRP74053.1 - 4.5e-09 36.6 0.1 1.9e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Aida N-terminus CT_C_D PF02682.16 PRP74053.1 - 0.16 11.7 0.0 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D EF-hand_7 PF13499.6 PRP74054.1 - 6.7e-12 45.7 2.4 1.6e-09 38.0 0.6 3.0 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP74054.1 - 6.5e-10 37.9 3.4 0.00014 21.1 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PRP74054.1 - 1.3e-09 37.2 3.4 0.004 17.0 0.1 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 PRP74054.1 - 6.7e-06 25.9 6.1 0.044 13.6 0.2 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP74054.1 - 2.4e-05 23.6 1.0 0.21 11.2 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 PRP74054.1 - 2.5e-05 24.0 1.6 0.025 14.4 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 PRP74054.1 - 0.0052 16.7 6.5 1.1 9.3 0.2 3.5 2 2 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PRP74054.1 - 0.1 12.9 1.4 20 5.5 0.9 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF962 PF06127.11 PRP74055.1 - 2.5e-08 33.9 0.0 6.1e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) RuvA_C PF07499.13 PRP74055.1 - 0.011 16.2 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 RuvA, C-terminal domain DUF2937 PF11157.8 PRP74055.1 - 0.054 13.2 1.7 0.57 9.9 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) FAM76 PF16046.5 PRP74055.1 - 0.16 11.3 2.7 0.28 10.5 2.7 1.4 1 0 0 1 1 1 0 FAM76 protein PQQ_2 PF13360.6 PRP74056.1 - 0.0053 16.4 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 2 PQQ-like domain Strumpellin PF10266.9 PRP74057.1 - 0 1463.2 23.1 0 1463.0 23.1 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin COLFI PF01410.18 PRP74057.1 - 0.052 12.8 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain UNC-93 PF05978.16 PRP74058.1 - 9.7e-15 54.6 15.2 9.7e-15 54.6 15.2 2.9 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 ACP_PD PF04336.12 PRP74059.1 - 0.0089 16.4 3.7 0.12 12.8 0.5 2.3 1 1 1 2 2 2 2 Acyl carrier protein phosphodiesterase Ead_Ea22 PF13935.6 PRP74059.1 - 0.029 15.0 2.5 0.042 14.5 2.2 1.4 1 1 0 1 1 1 0 Ead/Ea22-like protein ApoO PF09769.9 PRP74059.1 - 0.048 13.6 2.8 1.3 8.9 0.3 2.2 1 1 1 2 2 2 0 Apolipoprotein O GIDA_assoc PF13932.6 PRP74059.1 - 0.1 12.8 8.7 0.13 12.5 8.7 1.1 1 0 0 1 1 1 0 GidA associated domain RapH_N PF18801.1 PRP74059.1 - 0.11 12.6 0.6 0.11 12.6 0.6 2.0 2 1 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal Integrase_H2C2 PF17921.1 PRP74059.1 - 0.16 12.1 1.7 0.16 12.1 0.3 1.8 2 0 0 2 2 2 0 Integrase zinc binding domain P4Ha_N PF08336.11 PRP74059.1 - 0.99 9.4 9.1 0.08 13.0 1.7 2.5 1 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DIT1_PvcA PF05141.12 PRP74059.1 - 1.7 8.0 6.3 2.4 7.5 6.3 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF883 PF05957.13 PRP74059.1 - 1.9 9.1 8.7 1.5 9.5 0.9 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_3_C PF01915.22 PRP74061.1 - 5.7e-44 150.5 0.0 9.3e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PRP74061.1 - 1.6e-37 129.6 0.0 2.6e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 PRP74061.1 - 1.4e-18 66.8 0.1 3.3e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain F-box-like PF12937.7 PRP74061.1 - 0.15 12.0 0.3 0.34 10.9 0.3 1.5 1 0 0 1 1 1 0 F-box-like GDP_Man_Dehyd PF16363.5 PRP74062.1 - 1.3e-56 192.4 0.0 1.5e-56 192.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PRP74062.1 - 9.5e-51 172.6 0.0 1.1e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PRP74062.1 - 3.4e-14 52.7 0.1 6.7e-13 48.4 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 PRP74062.1 - 7.1e-13 48.2 0.2 6.6e-12 45.0 0.3 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PRP74062.1 - 3.5e-10 39.5 0.1 2e-08 33.7 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 PRP74062.1 - 1.6e-06 27.5 0.0 2.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 PRP74062.1 - 4.7e-06 26.6 0.0 1.2e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 PRP74062.1 - 0.00036 20.5 0.0 0.00062 19.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 PRP74062.1 - 0.00054 19.5 0.0 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 PRP74062.1 - 0.0052 16.4 0.2 0.017 14.7 0.2 1.8 1 1 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 PRP74062.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sec8_exocyst PF04048.14 PRP74064.1 - 1.8e-22 79.8 3.5 2.1e-22 79.5 0.3 2.7 2 1 1 3 3 3 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 PRP74064.1 - 1.2e-07 31.3 2.8 1.2e-07 31.3 2.8 2.3 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 PRP74064.1 - 4e-06 26.9 1.3 4e-06 26.9 1.3 3.6 5 0 0 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 LXG PF04740.12 PRP74064.1 - 0.0066 16.2 1.7 0.034 13.8 1.0 2.6 2 0 0 2 2 2 1 LXG domain of WXG superfamily TACC_C PF05010.14 PRP74064.1 - 0.0073 16.1 4.1 0.0073 16.1 4.1 2.3 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Laminin_II PF06009.12 PRP74064.1 - 0.02 14.9 0.9 0.02 14.9 0.9 2.4 2 0 0 2 2 2 0 Laminin Domain II YscO PF07321.12 PRP74064.1 - 0.025 14.5 6.5 0.84 9.6 0.6 2.9 2 0 0 2 2 2 0 Type III secretion protein YscO SlyX PF04102.12 PRP74064.1 - 0.041 14.5 0.0 0.041 14.5 0.0 4.6 4 0 0 4 4 3 0 SlyX DTHCT PF08070.11 PRP74064.1 - 0.045 14.5 30.9 0.024 15.4 17.9 2.9 1 1 1 2 2 2 0 DTHCT (NUC029) region Sec5 PF15469.6 PRP74064.1 - 1.2 8.9 13.6 0.019 14.7 1.8 3.1 3 0 0 3 3 3 0 Exocyst complex component Sec5 FliJ PF02050.16 PRP74064.1 - 4.7 7.5 8.6 1.4 9.2 4.4 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein Occludin_ELL PF07303.13 PRP74064.1 - 7.5 7.4 13.2 0.11 13.3 3.1 3.2 2 1 0 3 3 2 0 Occludin homology domain DUF4363 PF14276.6 PRP74064.1 - 7.5 6.7 9.7 1.7 8.8 3.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Acyltransferase PF01553.21 PRP74065.1 - 5.2e-17 61.7 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase RWD PF05773.22 PRP74066.1 - 4.8e-11 43.0 0.2 1e-10 41.9 0.2 1.6 1 0 0 1 1 1 1 RWD domain F-box PF00646.33 PRP74066.1 - 1.1e-07 31.6 0.0 2.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP74066.1 - 1.4e-06 28.1 0.0 6.3e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 PRP74066.1 - 0.00018 21.4 0.1 0.00045 20.1 0.1 1.7 1 0 0 1 1 1 1 F-box PI3_PI4_kinase PF00454.27 PRP74067.1 - 2e-51 175.2 0.8 3.3e-50 171.3 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PRP74067.1 - 5.5e-51 172.6 0.2 9.8e-51 171.8 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_rbd PF00794.18 PRP74067.1 - 2.6e-13 50.1 0.0 4.4e-11 42.9 0.0 2.5 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 PRP74067.1 - 7.8e-13 48.5 0.0 1.9e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 PRP74067.1 - 0.014 14.8 0.2 0.029 13.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) PSI PF01437.25 PRP74067.1 - 1.2 9.7 7.8 3.4 8.3 7.8 1.8 1 0 0 1 1 1 0 Plexin repeat RPEL PF02755.15 PRP74068.1 - 0.00021 20.9 14.8 0.003 17.2 0.1 3.6 3 1 1 4 4 4 2 RPEL repeat RNA_pol_L_2 PF13656.6 PRP74070.1 - 3.4e-26 90.8 0.1 4.6e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 PRP74070.1 - 7.8e-08 31.6 0.0 1.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4201 PF13870.6 PRP74071.1 - 8.8e-38 129.8 19.2 8.8e-38 129.8 19.2 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) SBDS_C PF09377.10 PRP74071.1 - 0.056 13.5 4.5 1.4 8.9 4.4 3.0 1 1 1 2 2 2 0 SBDS protein C-terminal domain DUF883 PF05957.13 PRP74071.1 - 1.1 10.0 4.2 1.1 10.0 1.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PSP PF04046.16 PRP74072.1 - 0.015 15.1 0.6 0.039 13.8 0.0 2.0 2 0 0 2 2 2 0 PSP DUF5133 PF17196.4 PRP74072.1 - 0.25 11.5 4.0 1.2 9.3 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF5133) DUF2576 PF10845.8 PRP74072.1 - 0.62 9.7 6.9 0.59 9.8 0.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2576) CRF PF00473.17 PRP74072.1 - 1.6 8.8 7.2 5 7.3 0.4 4.1 3 0 0 3 3 3 0 Corticotropin-releasing factor family TPR_2 PF07719.17 PRP74073.1 - 1.2e-31 106.2 10.0 0.0036 17.3 0.0 9.1 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_1 PF00515.28 PRP74073.1 - 2.2e-31 106.4 5.8 0.00068 19.4 0.0 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 PRP74073.1 - 2.2e-22 79.4 0.0 7.6e-08 32.9 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP74073.1 - 5.4e-22 78.1 3.3 7.9e-07 29.5 0.0 5.4 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.6 PRP74073.1 - 2.8e-20 72.2 0.9 0.0015 18.6 0.0 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.6 PRP74073.1 - 6.9e-20 70.3 8.8 0.0013 19.3 0.0 8.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 PRP74073.1 - 2.8e-16 59.6 15.4 1.5e-05 25.1 0.4 6.6 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 PRP74073.1 - 4.4e-14 51.4 13.3 0.19 12.0 0.6 8.8 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP74073.1 - 4.5e-14 51.8 1.7 0.0042 16.7 0.0 6.3 4 3 2 6 6 6 3 TPR repeat TPR_14 PF13428.6 PRP74073.1 - 3.2e-13 49.3 4.1 0.48 11.4 0.1 7.6 3 1 6 9 9 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP74073.1 - 2.6e-12 46.8 9.7 3.4e-05 24.0 0.1 4.8 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PRP74073.1 - 1.1e-09 38.0 4.5 0.38 11.2 0.1 6.5 6 0 0 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP74073.1 - 1.1e-06 28.6 11.4 1.2 9.3 0.0 6.8 7 1 1 8 8 8 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 PRP74073.1 - 1.5e-06 27.6 0.8 0.012 14.8 0.1 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat NARP1 PF12569.8 PRP74073.1 - 4.8e-05 22.5 0.8 0.24 10.3 0.1 3.5 1 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 PRP74073.1 - 8.9e-05 22.3 13.0 4.8 7.4 0.0 7.5 7 1 0 7 7 7 1 Tetratricopeptide repeat BTAD PF03704.17 PRP74073.1 - 0.00019 21.9 8.4 0.37 11.2 1.9 4.0 1 1 3 4 4 4 2 Bacterial transcriptional activator domain SRP_TPR_like PF17004.5 PRP74073.1 - 0.00023 21.2 1.6 0.049 13.6 0.1 3.4 1 1 1 2 2 2 1 Putative TPR-like repeat TPR_18 PF13512.6 PRP74073.1 - 0.0012 19.0 1.9 0.038 14.1 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP74073.1 - 0.0017 17.8 4.0 0.069 12.5 0.0 3.6 2 1 2 4 4 4 2 MalT-like TPR region DUF3856 PF12968.7 PRP74073.1 - 0.0048 17.0 4.3 25 4.9 0.0 5.0 3 2 2 5 5 5 0 Domain of Unknown Function (DUF3856) Coatomer_E PF04733.14 PRP74073.1 - 0.0051 16.3 0.3 0.13 11.6 0.0 2.5 1 1 2 3 3 3 1 Coatomer epsilon subunit PknG_TPR PF16918.5 PRP74073.1 - 0.0058 15.4 0.0 0.14 10.8 0.0 2.6 1 1 2 3 3 3 2 Protein kinase G tetratricopeptide repeat PSCyt3 PF07627.11 PRP74073.1 - 0.0098 16.1 0.2 1.7 9.0 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1588) RPN7 PF10602.9 PRP74073.1 - 0.019 14.7 3.0 0.065 12.9 0.2 3.2 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 PRP74073.1 - 0.099 12.5 15.6 5.4 7.0 0.1 6.8 9 0 0 9 9 7 0 Tetratricopeptide repeat CorA PF01544.18 PRP74074.1 - 1e-39 136.6 0.2 2.1e-39 135.6 0.2 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PH PF00169.29 PRP74074.1 - 9.4e-13 48.6 1.8 2.7e-12 47.1 0.2 2.7 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 PRP74074.1 - 2.9e-08 33.9 0.1 7.5e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Nuc_recep-AF1 PF11825.8 PRP74074.1 - 0.1 12.7 0.2 0.28 11.2 0.2 1.7 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 RabGAP-TBC PF00566.18 PRP74077.1 - 1.4e-49 168.7 0.6 1.9e-49 168.3 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PCI PF01399.27 PRP74078.1 - 1.4e-08 35.2 0.8 3e-08 34.1 0.8 1.6 1 1 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 PRP74078.1 - 9.4e-07 28.6 0.5 2.2e-06 27.5 0.5 1.6 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PS-DH PF14765.6 PRP74078.1 - 0.089 12.0 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Polyketide synthase dehydratase Fib_alpha PF08702.10 PRP74078.1 - 0.81 9.9 3.0 0.59 10.3 0.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MtrB_PioB PF11854.8 PRP74079.1 - 0.12 10.7 0.1 0.17 10.2 0.1 1.1 1 0 0 1 1 1 0 Putative outer membrane beta-barrel porin, MtrB/PioB Zn_clus PF00172.18 PRP74081.1 - 0.0001 22.3 11.1 0.0001 22.3 11.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 PRP74081.1 - 0.042 13.8 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold EMC3_TMCO1 PF01956.16 PRP74081.1 - 0.058 13.1 0.2 0.058 13.1 0.2 1.8 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like QRPTase_C PF01729.19 PRP74082.1 - 1.1e-56 191.2 0.0 1.7e-56 190.6 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 PRP74082.1 - 1.1e-18 67.0 0.0 2.6e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 PRP74082.1 - 0.099 12.0 0.0 0.3 10.4 0.0 1.7 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family UMPH-1 PF05822.12 PRP74082.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) PrmC_N PF17827.1 PRP74083.1 - 7.6e-05 23.2 0.0 0.00016 22.2 0.0 1.5 1 0 0 1 1 1 1 PrmC N-terminal domain Methyltransf_25 PF13649.6 PRP74083.1 - 0.0087 16.8 0.0 0.08 13.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP74083.1 - 0.079 13.6 0.0 1.8 9.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PhoLip_ATPase_C PF16212.5 PRP74084.1 - 3.4e-66 223.5 18.0 3.4e-66 223.5 18.0 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP74084.1 - 8.2e-22 76.7 0.7 2.4e-21 75.2 0.7 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 PRP74084.1 - 1.7e-14 53.6 0.1 1.8e-13 50.4 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PRP74084.1 - 2e-13 51.1 0.1 3e-09 37.5 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DPBB_1 PF03330.18 PRP74084.1 - 7.4e-05 23.0 0.1 0.00026 21.2 0.1 2.0 1 1 0 1 1 1 1 Lytic transglycolase Hydrolase_3 PF08282.12 PRP74084.1 - 0.00037 20.3 0.4 0.034 13.9 0.1 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 PRP74085.1 - 3.2e-06 26.9 6.5 7.7e-06 25.7 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP74085.1 - 0.0004 20.2 3.7 0.00089 19.1 3.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PRP74085.1 - 0.16 11.8 4.7 0.42 10.5 4.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NTF2 PF02136.20 PRP74086.1 - 1e-30 106.8 0.2 1.1e-30 106.6 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 PRP74086.1 - 0.00029 21.2 0.0 0.00035 20.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 PRP74086.1 - 0.12 13.0 0.0 0.16 12.7 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Gly-zipper_YMGG PF13441.6 PRP74087.1 - 0.16 11.7 6.0 0.66 9.8 6.0 1.8 1 1 1 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 PRP74087.1 - 7 6.5 11.1 13 5.7 4.2 2.2 2 0 0 2 2 2 0 Glycine-zipper domain Exonuc_VII_L PF02601.15 PRP74088.1 - 0.015 14.9 5.7 0.017 14.7 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4458 PF14660.6 PRP74088.1 - 0.04 14.2 3.4 0.099 12.9 3.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4458) P35 PF02331.15 PRP74088.1 - 0.083 12.2 3.1 0.13 11.6 3.1 1.2 1 0 0 1 1 1 0 Apoptosis preventing protein FUSC PF04632.12 PRP74088.1 - 0.41 9.1 2.5 0.56 8.7 2.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0020 PF01170.18 PRP74089.1 - 7.6e-20 71.4 0.1 2.8e-19 69.6 0.1 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 PRP74089.1 - 2e-06 28.0 0.0 3.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 THUMP domain MTS PF05175.14 PRP74089.1 - 3.5e-06 26.7 0.0 5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PRP74089.1 - 2.4e-05 24.2 0.0 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP74089.1 - 8.8e-05 23.1 0.0 0.00015 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 PRP74089.1 - 0.00099 18.5 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase AviRa PF11599.8 PRP74089.1 - 0.0012 18.3 0.0 0.37 10.2 0.0 2.1 1 1 1 2 2 2 2 RRNA methyltransferase AviRa Pox_MCEL PF03291.16 PRP74089.1 - 0.11 11.6 0.0 0.3 10.2 0.0 1.5 1 1 0 1 1 1 0 mRNA capping enzyme HU-CCDC81_euk_1 PF14908.6 PRP74090.1 - 0.045 13.9 0.2 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 1 LRR_4 PF12799.7 PRP74092.1 - 4.2e-11 42.9 23.6 2.3e-05 24.6 0.1 6.6 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP74092.1 - 2.5e-06 27.1 20.8 0.00079 19.1 1.4 5.4 3 1 3 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 PRP74092.1 - 0.015 14.9 3.3 3.5 7.1 0.4 2.8 1 1 1 2 2 2 0 Leucine-rich repeat Herpes_PAP PF03325.13 PRP74092.1 - 0.033 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein UQ_con PF00179.26 PRP74093.1 - 3.1e-48 163.0 0.0 3.5e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PRP74093.1 - 4.5e-05 23.2 0.0 5.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PRP74093.1 - 0.053 13.8 0.0 0.068 13.5 0.0 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 PRP74093.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF1910 PF08928.10 PRP74094.1 - 0.034 14.1 0.3 0.034 14.1 0.3 3.1 4 1 0 4 4 4 0 Domain of unknown function (DUF1910) GIDA PF01134.22 PRP74097.1 - 5.2e-135 450.5 0.0 8e-134 446.6 0.0 2.1 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 PRP74097.1 - 2.1e-65 220.8 0.1 3.1e-65 220.3 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 PRP74097.1 - 3e-08 33.5 0.1 6.1e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP74097.1 - 1.3e-05 24.6 1.6 4.2e-05 22.9 1.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP74097.1 - 4.6e-05 22.7 2.0 5.4e-05 22.5 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 PRP74097.1 - 0.00088 18.6 0.3 0.0017 17.7 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 PRP74097.1 - 0.0073 15.6 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PRP74097.1 - 0.0074 15.4 0.5 0.069 12.2 0.3 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 PRP74097.1 - 0.014 15.9 1.4 0.025 15.1 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP74097.1 - 0.05 12.3 3.0 0.11 11.2 1.5 2.2 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 PRP74097.1 - 0.11 11.7 0.3 0.17 11.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pkinase_Tyr PF07714.17 PRP74098.1 - 1.4e-72 244.1 0.0 1.9e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74098.1 - 8.9e-49 166.2 0.0 1.3e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Insulin_TMD PF17870.1 PRP74098.1 - 0.066 13.3 0.2 0.15 12.2 0.2 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Kdo PF06293.14 PRP74098.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP74098.1 - 0.15 10.8 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTP PF07504.13 PRP74098.1 - 0.28 11.0 4.6 3.1 7.7 0.1 3.3 3 0 0 3 3 3 0 Fungalysin/Thermolysin Propeptide Motif Beta-APP PF03494.13 PRP74098.1 - 0.39 10.6 2.6 1.2 9.0 2.6 1.8 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) TMEM154 PF15102.6 PRP74098.1 - 5.1 7.0 7.3 5.8 6.8 0.0 3.1 3 0 0 3 3 3 0 TMEM154 protein family GPS PF01825.21 PRP74099.1 - 4.1e-10 40.0 5.8 4.1e-10 40.0 5.8 3.0 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif LRR_8 PF13855.6 PRP74099.1 - 7.5e-10 38.4 9.8 3.5e-06 26.7 2.4 3.5 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PRP74099.1 - 1.7e-09 37.8 12.9 8.1e-05 22.9 1.4 5.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) EphA2_TM PF14575.6 PRP74099.1 - 0.033 15.1 0.1 0.14 13.0 0.2 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRR_1 PF00560.33 PRP74099.1 - 0.076 13.6 12.7 12 6.9 0.4 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat DUF4772 PF15997.5 PRP74099.1 - 0.095 13.3 0.0 0.31 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4772) BatA PF07584.11 PRP74099.1 - 0.21 12.0 0.2 0.69 10.3 0.0 1.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal CoA_transf_3 PF02515.17 PRP74104.1 - 6.2e-127 423.7 0.0 7.2e-127 423.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III TTL PF03133.15 PRP74105.1 - 1.8e-85 286.6 2.5 3.1e-85 285.9 2.5 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PRP74105.1 - 3.6e-09 36.2 0.0 0.00016 21.0 0.0 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PRP74105.1 - 2.1e-05 23.9 0.0 0.00056 19.2 0.0 2.4 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF2115 PF09888.9 PRP74105.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) PI31_Prot_N PF11566.8 PRP74107.1 - 3.8e-33 114.6 0.0 4.8e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 PRP74107.1 - 3.8e-08 34.4 17.1 3.8e-08 34.4 17.1 2.6 3 0 0 3 3 3 1 PI31 proteasome regulator Calci_bind_CcbP PF11535.8 PRP74108.1 - 0.18 12.3 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Calcium binding Mtp PF03821.16 PRP74109.1 - 0.072 12.7 0.1 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter DUF4423 PF14394.6 PRP74110.1 - 0.067 12.9 0.2 2.8 7.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) MFS_1 PF07690.16 PRP74111.1 - 2e-08 33.5 11.1 3.2e-08 32.9 11.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily CD20 PF04103.15 PRP74111.1 - 8.8 6.4 11.3 2.4 8.2 2.2 2.2 2 0 0 2 2 2 0 CD20-like family Pkinase_Tyr PF07714.17 PRP74112.1 - 5.4e-236 779.7 0.0 3.8e-64 216.5 0.0 5.6 4 1 1 5 5 5 5 Protein tyrosine kinase Pkinase PF00069.25 PRP74112.1 - 4.8e-149 494.9 0.0 4.7e-40 137.6 0.0 5.6 5 0 0 5 5 5 5 Protein kinase domain Kinase-like PF14531.6 PRP74112.1 - 3e-10 39.9 0.0 0.2 10.9 0.0 4.6 4 0 0 4 4 4 3 Kinase-like Kdo PF06293.14 PRP74112.1 - 7e-08 32.1 1.1 0.072 12.4 0.0 4.6 4 0 0 4 4 4 3 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP74112.1 - 1.6e-05 24.0 0.3 11 4.8 0.0 4.5 4 0 0 4 4 4 4 Haspin like kinase domain APH PF01636.23 PRP74112.1 - 0.00044 20.3 2.9 24 4.8 0.1 5.0 4 1 1 5 5 5 0 Phosphotransferase enzyme family SLATT_fungal PF18142.1 PRP74112.1 - 0.025 14.6 2.9 2.3 8.2 0.1 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain CopK PF11525.8 PRP74112.1 - 0.11 12.1 0.6 11 5.7 0.0 2.9 2 0 0 2 2 2 0 Copper resistance protein K Pkinase_Tyr PF07714.17 PRP74113.1 - 1.2e-59 201.7 0.0 3.5e-54 183.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP74113.1 - 7.1e-50 169.8 0.0 3.5e-36 124.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain AAA_16 PF13191.6 PRP74113.1 - 4.2e-36 124.9 0.0 9.6e-36 123.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain HATPase_c PF02518.26 PRP74113.1 - 3.8e-25 88.6 0.1 1.5e-24 86.7 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP74113.1 - 2e-20 73.1 0.2 6.4e-20 71.4 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 PRP74113.1 - 7.1e-09 35.6 0.1 2.6e-08 33.8 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 PRP74113.1 - 0.00022 21.8 0.0 0.00077 20.1 0.0 2.0 1 0 0 1 1 1 1 GAF domain Chlam_PMP PF02415.17 PRP74113.1 - 0.00094 19.5 11.3 4.6 7.9 0.0 6.9 7 0 0 7 7 6 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat HATPase_c_3 PF13589.6 PRP74113.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.6 PRP74113.1 - 0.0044 17.3 0.0 0.12 12.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain FAT PF02259.23 PRP74113.1 - 0.013 14.7 0.9 0.024 13.8 0.9 1.4 1 0 0 1 1 1 0 FAT domain GAF_2 PF13185.6 PRP74113.1 - 0.013 15.8 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 GAF domain NB-ARC PF00931.22 PRP74113.1 - 0.04 13.1 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 PRP74113.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 PRP74113.1 - 0.079 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TPR_1 PF00515.28 PRP74113.1 - 0.11 12.3 0.4 0.53 10.2 0.4 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP74113.1 - 0.12 12.7 14.7 0.057 13.7 1.7 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 PRP74113.1 - 0.13 11.8 1.0 0.32 10.4 0.4 2.0 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 PRP74113.1 - 0.13 12.8 1.8 0.33 11.5 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 PRP74113.1 - 0.14 12.2 0.4 0.87 9.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP74113.1 - 0.2 11.6 0.3 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.6 PRP74113.1 - 0.81 9.0 3.4 2 7.8 0.4 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 PRP74113.1 - 0.83 9.9 10.1 0.052 13.7 0.2 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP74113.1 - 1.1 9.9 4.2 1.2 9.8 0.2 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat FGGY_C PF02782.16 PRP74114.1 - 2.4e-43 148.2 0.1 4.4e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 PRP74114.1 - 2.4e-23 83.0 0.0 5.5e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain HTH_ParB PF17762.1 PRP74115.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 HTH domain found in ParB protein PPR PF01535.20 PRP74115.1 - 0.23 11.8 1.6 14 6.2 0.0 3.8 4 0 0 4 4 4 0 PPR repeat PPR_2 PF13041.6 PRP74115.1 - 0.97 9.7 5.3 2 8.7 0.1 3.5 4 1 1 5 5 5 0 PPR repeat family Profilin PF00235.19 PRP74116.1 - 2.9e-12 47.0 0.0 3.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 Profilin ATP_bind_3 PF01171.20 PRP74117.1 - 7.2e-18 65.0 0.0 1.1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 PRP74117.1 - 4.7e-17 61.2 2.4 4.7e-17 61.2 2.4 3.5 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 PRP74117.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase PRESAN PF09687.10 PRP74118.1 - 0.0062 17.1 0.2 0.15 12.6 0.0 2.5 2 0 0 2 2 2 1 Plasmodium RESA N-terminal WD40 PF00400.32 PRP74119.1 - 2e-45 151.9 28.7 1.8e-06 28.6 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat BTB_2 PF02214.22 PRP74119.1 - 4.4e-23 81.4 0.0 1.2e-12 47.9 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain WD40_like PF17005.5 PRP74119.1 - 3.9e-05 23.1 0.3 0.013 14.9 0.1 3.0 1 1 2 3 3 3 2 WD40-like domain SoxE PF06525.11 PRP74119.1 - 0.24 10.9 2.0 5.4 6.5 0.3 2.6 2 0 0 2 2 2 0 Sulfocyanin (SoxE) domain RNA_pol_A_bac PF01000.26 PRP74119.1 - 0.68 10.3 2.8 0.73 10.2 0.8 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb3/RpoA insert domain MFS_1 PF07690.16 PRP74120.1 - 7.2e-32 110.7 42.0 7.2e-32 110.7 42.0 2.2 2 1 1 3 3 3 1 Major Facilitator Superfamily hSac2 PF12456.8 PRP74120.1 - 5.3e-16 58.4 0.1 1.1e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Inositol phosphatase C2 PF00168.30 PRP74120.1 - 2.3e-12 47.1 0.0 6.4e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 C2 domain Guanylate_cyc PF00211.20 PRP74121.1 - 8.8e-25 87.4 0.3 1.7e-24 86.5 0.3 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Response_reg PF00072.24 PRP74121.1 - 0.00073 19.7 0.0 0.0025 18.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS PF00989.25 PRP74121.1 - 0.091 12.8 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 PAS fold SNase PF00565.17 PRP74122.1 - 1e-63 212.6 9.0 3.8e-19 69.2 0.1 5.6 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 PRP74122.1 - 2.1e-21 76.2 0.0 5.5e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Tudor domain PsbP PF01789.16 PRP74122.1 - 0.019 15.1 1.4 0.13 12.3 0.1 2.5 2 0 0 2 2 2 0 PsbP RF-1 PF00472.20 PRP74122.1 - 1.3 9.0 5.2 0.6 10.1 1.3 2.5 2 0 0 2 2 2 0 RF-1 domain HATPase_c PF02518.26 PRP74123.1 - 1.1e-32 112.8 1.9 5.4e-20 72.0 0.2 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP74123.1 - 1.2e-21 77.0 0.1 6.1e-14 52.1 0.1 2.9 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 PRP74123.1 - 1.3e-20 73.2 3.8 2.7e-09 36.9 0.0 3.1 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain Lipase_3 PF01764.25 PRP74123.1 - 1.6e-17 63.7 0.0 3.9e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) HATPase_c_3 PF13589.6 PRP74123.1 - 2.2e-06 27.5 0.0 0.026 14.4 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hydrolase_4 PF12146.8 PRP74123.1 - 0.075 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Tna_leader PF08053.11 PRP74123.1 - 0.13 12.2 0.3 28 4.9 0.0 3.2 2 0 0 2 2 2 0 Tryptophanase operon leader peptide Alpha_L_fucos PF01120.17 PRP74125.1 - 4.9e-111 371.5 9.9 9.6e-111 370.6 9.9 1.4 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 PRP74125.1 - 7.8e-16 58.4 0.0 1.9e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain APC1_C PF18122.1 PRP74125.1 - 0.19 11.7 0.5 1.1 9.2 0.1 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain Chorismate_synt PF01264.21 PRP74126.1 - 1e-136 455.0 1.6 2.9e-136 453.5 1.6 1.6 1 1 0 1 1 1 1 Chorismate synthase CRAL_TRIO PF00650.20 PRP74127.1 - 5.9e-10 39.1 0.0 8.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Pkinase_Tyr PF07714.17 PRP74128.1 - 1.1e-64 218.2 0.2 1.4e-63 214.6 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74128.1 - 3.5e-42 144.6 0.0 1.2e-41 142.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP74128.1 - 0.023 14.0 0.1 0.05 13.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP74128.1 - 0.024 14.0 0.0 0.066 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like ASFV_J13L PF05568.11 PRP74128.1 - 0.041 13.7 0.1 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein IMP2_C PF18591.1 PRP74128.1 - 0.057 13.3 0.1 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Immune Mapped Protein 2 (IMP2) C-terminal domain LIM PF00412.22 PRP74129.1 - 3.1e-09 36.9 3.1 5.1e-09 36.2 3.1 1.3 1 0 0 1 1 1 1 LIM domain zf-C2H2 PF00096.26 PRP74129.1 - 0.046 14.2 1.5 1.8 9.2 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-ACC PF17848.1 PRP74129.1 - 0.11 12.6 5.0 0.33 11.1 1.7 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Pyridoxal_deC PF00282.19 PRP74130.1 - 7.7e-17 61.1 0.0 1.7e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 PRP74130.1 - 9.2e-09 34.7 0.7 3.2e-08 32.9 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PRP74130.1 - 4.5e-05 22.9 0.1 4.5e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 PRP74130.1 - 0.016 14.4 4.4 0.038 13.2 0.0 2.9 2 1 0 2 2 2 0 Aminotransferase class I and II ATG16 PF08614.11 PRP74130.1 - 2 8.6 81.8 0.12 12.6 23.1 4.8 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF2937 PF11157.8 PRP74130.1 - 2.4 7.9 4.4 10 5.8 4.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Glucosamine_iso PF01182.20 PRP74131.1 - 6.1e-45 153.8 0.0 7.5e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase TgMIC1 PF11476.8 PRP74131.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 SPA PF08616.10 PRP74132.1 - 2.9e-13 49.8 0.4 7.9e-13 48.4 0.2 1.8 2 0 0 2 2 2 1 Stabilization of polarity axis DUF2347 PF09804.9 PRP74132.1 - 5.9e-06 26.1 0.2 1.7e-05 24.6 0.2 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 PRP74132.1 - 0.00029 19.7 0.1 0.47 9.1 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 DENN PF02141.21 PRP74132.1 - 0.042 13.8 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 DENN (AEX-3) domain PolyA_pol PF01743.20 PRP74133.1 - 4.9e-32 111.0 0.4 1.1e-31 109.9 0.4 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 PRP74133.1 - 0.0039 16.9 0.1 0.023 14.4 0.1 2.2 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 PRP74133.1 - 0.025 14.6 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Ribosomal_L9_N PF01281.19 PRP74133.1 - 0.18 11.4 0.6 0.41 10.3 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L9, N-terminal domain Ank_2 PF12796.7 PRP74134.1 - 1.9e-37 127.7 0.0 1.5e-08 35.1 0.0 5.5 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP74134.1 - 1.3e-29 102.2 5.1 0.00023 21.7 0.1 9.4 3 3 8 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP74134.1 - 3.7e-20 69.9 3.1 0.25 12.0 0.1 12.3 13 0 0 13 13 13 3 Ankyrin repeat Ank_5 PF13857.6 PRP74134.1 - 2.9e-19 68.9 6.7 0.0012 19.1 0.0 9.8 3 3 8 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP74134.1 - 7.3e-17 61.0 15.8 0.018 15.5 0.1 11.7 12 1 1 13 13 13 4 Ankyrin repeat YlzJ PF14035.6 PRP74134.1 - 0.2 11.9 0.1 19 5.5 0.0 3.6 4 0 0 4 4 4 0 YlzJ-like protein DUF4395 PF14340.6 PRP74135.1 - 1.4e-16 61.0 11.8 1.4e-16 61.0 11.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4395) FA_hydroxylase PF04116.13 PRP74136.1 - 2.6e-21 76.3 10.1 2.6e-21 76.3 10.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_63 PF03200.16 PRP74137.1 - 2.4e-08 33.2 3.5 1.7e-05 23.8 0.2 3.5 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain INO80_Ies4 PF08193.11 PRP74137.1 - 0.26 11.3 2.3 0.47 10.4 2.3 1.4 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Bap31_Bap29_C PF18035.1 PRP74137.1 - 0.31 11.1 2.6 0.79 9.8 2.6 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Glyco_hydro81C PF17652.1 PRP74138.1 - 1.5e-32 113.2 0.0 2.4e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 PRP74138.1 - 2e-15 56.8 0.7 2e-09 37.1 0.0 2.5 2 1 1 3 3 3 2 Glycosyl hydrolase family 81 N-terminal domain DUF2374 PF09574.10 PRP74138.1 - 5.5 6.9 6.2 0.48 10.3 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Pkinase_Tyr PF07714.17 PRP74139.1 - 5e-48 163.6 0.0 6.9e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74139.1 - 8.8e-40 136.7 0.0 1.4e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_18 PF00704.28 PRP74139.1 - 2.2e-26 93.3 1.7 3e-26 92.9 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Kdo PF06293.14 PRP74139.1 - 1.6e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DAG1 PF05454.11 PRP74139.1 - 0.00072 19.0 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF3377 PF11857.8 PRP74139.1 - 0.015 15.2 0.6 0.033 14.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TMEM154 PF15102.6 PRP74139.1 - 0.037 13.9 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Kinase-like PF14531.6 PRP74139.1 - 0.04 13.2 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 PRP74139.1 - 0.061 12.9 0.0 13 5.4 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PRP74139.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4448 PF14610.6 PRP74139.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Haspin_kinase PF12330.8 PRP74139.1 - 0.1 11.5 0.0 0.25 10.3 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain P5-ATPase PF12409.8 PRP74139.1 - 0.15 12.2 0.2 4.4 7.4 0.1 2.5 2 0 0 2 2 2 0 P5-type ATPase cation transporter RIFIN PF02009.16 PRP74139.1 - 1.2 8.9 5.5 2.2 8.1 5.5 1.3 1 0 0 1 1 1 0 Rifin ABC_tran PF00005.27 PRP74140.1 - 1.7e-50 171.1 0.4 3.1e-25 89.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 PRP74140.1 - 2e-22 79.0 6.2 2e-22 79.0 6.2 2.3 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 PRP74140.1 - 1.1e-16 61.5 6.2 0.0013 18.6 0.8 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PRP74140.1 - 6.7e-09 35.5 0.3 0.037 13.4 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PRP74140.1 - 1.8e-07 31.3 0.1 0.0066 16.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 PRP74140.1 - 2.4e-07 31.5 3.5 0.15 12.5 1.9 3.4 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PRP74140.1 - 3.1e-07 30.0 0.5 0.0084 15.8 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP74140.1 - 4.2e-07 30.5 0.6 0.0068 16.8 0.0 2.9 3 1 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PRP74140.1 - 6.1e-07 29.5 0.1 0.0041 17.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 PRP74140.1 - 7.2e-06 26.6 0.6 0.18 12.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 PRP74140.1 - 2.2e-05 24.3 1.5 0.33 10.6 0.0 3.6 3 1 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 PRP74140.1 - 2.6e-05 24.4 2.4 0.068 13.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 PRP74140.1 - 3.2e-05 24.2 4.3 0.076 13.3 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 PRP74140.1 - 0.00016 21.4 0.0 0.45 10.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PRP74140.1 - 0.00022 21.2 0.2 0.46 10.4 0.0 2.4 2 0 0 2 2 2 2 NACHT domain Dynamin_N PF00350.23 PRP74140.1 - 0.00039 20.5 2.4 0.34 10.9 0.0 3.1 2 1 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 PRP74140.1 - 0.00065 20.0 0.7 1.1 9.6 0.0 3.3 2 2 1 3 3 2 1 AAA domain RNA_helicase PF00910.22 PRP74140.1 - 0.0014 19.0 0.0 0.39 11.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 PRP74140.1 - 0.0033 17.2 0.0 3.4 7.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PRP74140.1 - 0.0042 16.4 0.0 0.054 12.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 PRP74140.1 - 0.0069 15.6 0.0 3.6 6.7 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 PRP74140.1 - 0.0075 16.7 0.0 3.7 8.0 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PRP74140.1 - 0.0084 15.6 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 PRP74140.1 - 0.0091 15.2 0.0 4.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 PRP74140.1 - 0.0092 15.6 0.1 2.1 7.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PRP74140.1 - 0.0096 15.9 1.5 4 7.4 0.1 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 PRP74140.1 - 0.014 14.9 0.1 1 8.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 PRP74140.1 - 0.02 14.8 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 PRP74140.1 - 0.022 14.5 0.0 9.2 6.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 PRP74140.1 - 0.023 13.8 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein cobW PF02492.19 PRP74140.1 - 0.025 14.1 0.3 7.8 6.0 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 PRP74140.1 - 0.032 14.4 0.2 8.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 PRP74140.1 - 0.035 12.7 6.2 0.99 8.0 0.0 3.1 2 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 PRP74140.1 - 0.051 13.6 0.3 7.5 6.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain MeaB PF03308.16 PRP74140.1 - 0.072 12.1 0.2 2.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 PRP74140.1 - 0.11 12.6 5.7 2 8.5 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain NTPase_1 PF03266.15 PRP74140.1 - 0.12 12.3 0.3 16 5.4 0.0 2.9 3 0 0 3 3 2 0 NTPase MukB PF04310.12 PRP74140.1 - 0.12 12.2 0.5 0.62 9.8 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal FtsK_SpoIIIE PF01580.18 PRP74140.1 - 0.14 11.5 0.1 12 5.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 PRP74140.1 - 0.15 12.0 0.2 6 6.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 PRP74140.1 - 0.18 11.4 4.6 4 7.0 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_27 PF13514.6 PRP74140.1 - 0.29 10.7 5.7 6.3 6.3 0.0 3.2 4 0 0 4 4 3 0 AAA domain DUF3584 PF12128.8 PRP74140.1 - 0.43 8.0 11.2 0.19 9.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Histone PF00125.24 PRP74141.1 - 1.1e-18 67.8 0.0 1.5e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 PRP74141.1 - 2.7e-18 65.4 0.8 5.8e-18 64.3 0.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 PRP74141.1 - 0.00034 20.8 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 PRP74142.1 - 3.5e-09 36.8 0.0 5.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 PRP74142.1 - 0.00011 22.2 0.1 0.00019 21.5 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 PRP74142.1 - 0.00019 21.7 0.2 0.00034 20.9 0.2 1.5 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 PRP74142.1 - 0.00033 20.9 0.0 0.00068 19.9 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PRP74142.1 - 0.0006 20.2 0.1 0.00084 19.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PRP74142.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 PRP74142.1 - 0.02 14.9 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Sod_Fe_C PF02777.18 PRP74143.1 - 1.2e-39 134.6 0.0 2.2e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PRP74143.1 - 1.5e-32 111.9 0.7 2.3e-32 111.3 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pkinase PF00069.25 PRP74144.1 - 1.2e-42 146.1 0.0 1.9e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74144.1 - 4.6e-31 108.0 0.0 6.5e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UPF0552 PF10574.9 PRP74144.1 - 1.2e-26 93.4 0.0 1.9e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin MIT PF04212.18 PRP74144.1 - 1.4e-17 63.5 7.1 2.7e-15 56.2 2.7 3.2 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain Kinase-like PF14531.6 PRP74144.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP74144.1 - 0.016 14.0 0.1 0.033 13.0 0.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase TPR_2 PF07719.17 PRP74144.1 - 2 8.7 4.4 2.3 8.5 0.4 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat FlxA PF14282.6 PRP74145.1 - 0.04 13.9 10.2 0.06 13.3 10.2 1.4 1 0 0 1 1 1 0 FlxA-like protein G_path_suppress PF15991.5 PRP74145.1 - 0.08 13.1 4.3 0.096 12.8 4.3 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor Cauli_AT PF03233.13 PRP74145.1 - 0.087 12.7 4.8 0.15 12.0 4.8 1.4 1 0 0 1 1 1 0 Aphid transmission protein Swi5 PF07061.11 PRP74145.1 - 0.19 11.8 5.8 0.31 11.2 5.8 1.3 1 0 0 1 1 1 0 Swi5 DUF2205 PF10224.9 PRP74145.1 - 0.78 9.8 6.0 1.3 9.1 5.6 1.5 1 1 0 1 1 1 0 Short coiled-coil protein DivIC PF04977.15 PRP74145.1 - 1 9.2 9.5 2.4 8.0 9.5 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4404 PF14357.6 PRP74145.1 - 1.1 10.0 6.8 1.7 9.3 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) YabA PF06156.13 PRP74145.1 - 1.1 9.9 6.6 1.6 9.4 6.6 1.2 1 0 0 1 1 1 0 Initiation control protein YabA TMPIT PF07851.13 PRP74145.1 - 6 6.0 11.9 3 7.0 4.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein F-box-like PF12937.7 PRP74146.1 - 2.5e-11 43.3 0.3 1.3e-10 41.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP74146.1 - 3.5e-09 36.3 0.0 7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain YhfH PF14149.6 PRP74146.1 - 0.009 16.0 0.6 0.042 13.8 0.1 2.5 3 0 0 3 3 3 1 YhfH-like protein zf-C2H2_3 PF13878.6 PRP74146.1 - 0.11 12.4 0.2 0.27 11.1 0.2 1.6 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO PhaP_Bmeg PF09602.10 PRP74147.1 - 0.017 15.1 0.1 0.021 14.8 0.1 1.1 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF1539 PF07560.11 PRP74147.1 - 0.057 13.5 0.1 0.064 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) MbeD_MobD PF04899.12 PRP74147.1 - 0.057 13.5 0.6 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 MbeD/MobD like NADPH_Ox PF08414.10 PRP74147.1 - 0.065 13.6 0.1 0.1 13.0 0.1 1.4 1 1 0 1 1 1 0 Respiratory burst NADPH oxidase OSCP PF00213.18 PRP74147.1 - 0.1 12.7 0.1 0.13 12.4 0.1 1.1 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Methyltransf_25 PF13649.6 PRP74148.1 - 5e-06 27.1 0.0 3.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain TPR_8 PF13181.6 PRP74148.1 - 0.0005 20.1 8.2 0.25 11.6 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP74148.1 - 0.00053 19.9 16.7 0.15 12.3 1.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP74148.1 - 0.0072 16.8 4.2 0.14 12.7 1.8 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_12 PF08242.12 PRP74148.1 - 0.018 15.7 0.0 0.079 13.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 PRP74148.1 - 0.029 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPR_1 PF00515.28 PRP74148.1 - 0.097 12.5 10.9 1.7 8.6 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3721 PF12518.8 PRP74148.1 - 0.22 11.4 2.3 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DEK_C PF08766.11 PRP74148.1 - 0.65 10.0 5.3 12 5.9 0.1 3.4 4 0 0 4 4 4 0 DEK C terminal domain TPR_10 PF13374.6 PRP74148.1 - 4.3 7.3 7.6 12 5.9 1.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP74148.1 - 4.9 7.9 17.9 0.18 12.5 7.4 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP74148.1 - 9.5 6.0 11.8 1.5 8.6 1.7 3.0 3 0 0 3 3 3 0 TPR repeat eIF-3_zeta PF05091.12 PRP74149.1 - 2.2e-153 512.0 0.7 2.5e-153 511.8 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MaoC_dehydratas PF01575.19 PRP74150.1 - 0.00012 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Smg4_UPF3 PF03467.15 PRP74150.1 - 0.039 14.0 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Cortexin PF11057.8 PRP74151.1 - 0.1 12.5 2.5 0.11 12.4 1.0 1.8 1 1 1 2 2 2 0 Cortexin of kidney PH PF00169.29 PRP74152.1 - 5.4e-12 46.1 0.1 9.2e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_4 PF15404.6 PRP74152.1 - 0.014 15.2 0.3 0.038 13.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain MutS_V PF00488.21 PRP74153.1 - 2.8e-74 249.3 0.3 4.8e-74 248.5 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PRP74153.1 - 1.1e-34 120.3 0.5 1.1e-34 120.3 0.5 2.4 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 PRP74153.1 - 4.7e-25 88.0 0.2 9.7e-24 83.8 0.2 2.7 1 1 0 1 1 1 1 MutS domain I MutS_II PF05188.17 PRP74153.1 - 3.2e-13 50.2 0.0 1.4e-12 48.0 0.0 2.2 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 PRP74153.1 - 5.6e-08 33.0 1.5 1.5e-07 31.6 1.5 1.8 1 0 0 1 1 1 1 MutS family domain IV CDC45 PF02724.14 PRP74153.1 - 0.018 13.4 6.0 0.03 12.6 6.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Herpes_UL92 PF03048.14 PRP74153.1 - 0.042 13.6 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 UL92 family AAA_29 PF13555.6 PRP74153.1 - 0.16 11.7 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RXT2_N PF08595.11 PRP74153.1 - 0.47 10.5 10.2 1.6 8.7 10.2 2.0 1 0 0 1 1 1 0 RXT2-like, N-terminal AAA_23 PF13476.6 PRP74153.1 - 1.1 9.7 0.0 1.1 9.7 0.0 4.0 5 0 0 5 5 5 0 AAA domain FAM176 PF14851.6 PRP74153.1 - 5.9 6.5 13.6 9.8 5.8 11.7 2.4 2 0 0 2 2 2 0 FAM176 family Ribosomal_60s PF00428.19 PRP74153.1 - 7.1 7.3 12.4 73 4.1 10.7 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein ATP_transf PF09830.9 PRP74154.1 - 2.1e-09 37.4 0.0 4.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 PRP74154.1 - 1.6e-07 30.9 0.3 1.7e-06 27.6 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 PRP74154.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) RT_RNaseH PF17917.1 PRP74157.1 - 5.5e-37 126.2 0.0 8e-37 125.7 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP74157.1 - 9e-26 89.8 0.0 1.7e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HEPN_AbiU2 PF18734.1 PRP74159.1 - 0.068 12.7 0.4 0.071 12.6 0.4 1.0 1 0 0 1 1 1 0 AbiU2 HNH_2 PF13391.6 PRP74163.1 - 0.00069 19.7 0.0 0.002 18.2 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease ECSCR PF15820.5 PRP74166.1 - 0.048 13.5 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator GCFC PF07842.12 PRP74169.1 - 0.0045 16.7 0.3 0.0052 16.4 0.3 1.1 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Baculo_PEP_C PF04513.12 PRP74170.1 - 0.042 13.9 0.9 0.08 13.0 0.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5344 PF17279.2 PRP74170.1 - 0.14 12.8 1.5 2.7 8.6 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5344) DUF726 PF05277.12 PRP74172.1 - 3.5e-98 328.7 0.3 4.6e-98 328.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Phage_holin_3_6 PF07332.11 PRP74172.1 - 0.074 13.1 3.0 0.16 12.0 3.0 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Helicase_C PF00271.31 PRP74174.1 - 4.6e-14 52.7 0.4 1.1e-13 51.4 0.4 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP74174.1 - 1.7e-12 47.4 0.0 4.8e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP74174.1 - 5.4e-11 42.8 0.1 2.4e-10 40.7 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PRP74174.1 - 0.13 12.5 0.1 0.72 10.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 PRP74174.1 - 0.31 11.5 2.1 1 9.8 0.0 2.9 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PTCB-BRCT PF12738.7 PRP74175.1 - 8.4e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain NIF PF03031.18 PRP74175.1 - 0.005 16.6 0.1 0.0092 15.8 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LIG3_BRCT PF16759.5 PRP74175.1 - 0.028 14.7 0.7 0.12 12.7 0.1 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Pkinase_Tyr PF07714.17 PRP74176.1 - 0.00019 20.8 0.5 0.0012 18.1 0.1 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Rsm22 PF09243.10 PRP74177.1 - 1.1e-51 175.8 0.0 1.1e-49 169.2 0.0 2.3 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Pkinase_Tyr PF07714.17 PRP74177.1 - 8.5e-28 97.3 0.0 1.7e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74177.1 - 1.7e-21 76.8 0.0 3.7e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Methyltransf_23 PF13489.6 PRP74177.1 - 2.3e-06 27.6 0.0 4.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP74177.1 - 0.085 13.6 0.0 0.62 10.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain RT_RNaseH PF17917.1 PRP74178.1 - 5.8e-81 267.6 0.1 1.4e-36 124.9 0.0 3.5 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP74178.1 - 4.2e-72 238.5 0.0 5.9e-32 109.7 0.0 3.6 3 0 0 3 3 3 3 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP74178.1 - 1.9e-44 149.6 8.4 1.4e-21 76.3 1.1 3.0 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 PRP74178.1 - 6.9e-32 110.7 1.7 1.2e-25 90.4 0.3 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.10 PRP74178.1 - 1.3e-15 57.3 1.4 2.1e-06 27.8 0.1 2.8 2 0 0 2 2 2 2 H2C2 zinc finger DUF2543 PF10820.8 PRP74178.1 - 4.3e-06 26.8 1.1 3.3 8.0 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF2543) DUF4125 PF13526.6 PRP74178.1 - 9.2e-06 25.4 0.8 0.66 9.6 0.1 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF4125) BCS1_N PF08740.11 PRP74178.1 - 0.00034 20.6 3.0 3.1 7.7 0.1 3.3 3 0 0 3 3 3 1 BCS1 N terminal DUF1712 PF08217.11 PRP74178.1 - 0.0023 16.5 0.1 1.2 7.5 0.0 2.2 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Get5_C PF18514.1 PRP74178.1 - 0.0055 16.4 0.1 46 3.9 0.0 3.8 3 0 0 3 3 3 0 Get5 C-terminal domain DUF727 PF05303.12 PRP74178.1 - 0.019 15.0 4.2 45 4.2 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF727) Pullulanase_Ins PF18494.1 PRP74178.1 - 0.038 14.5 3.7 59 4.2 0.1 4.2 4 0 0 4 4 4 0 Pullulanase Ins domain WbqC PF08889.11 PRP74178.1 - 0.044 13.7 4.7 25 4.7 0.1 3.4 3 0 0 3 3 3 0 WbqC-like protein family gag_pre-integrs PF13976.6 PRP74178.1 - 0.063 13.1 0.1 19 5.2 0.0 2.7 2 0 0 2 2 2 0 GAG-pre-integrase domain Dmd PF17587.2 PRP74178.1 - 0.074 13.4 11.9 48 4.4 0.1 5.5 5 0 0 5 5 5 0 Discriminator of mRNA degradation APOC4 PF15119.6 PRP74178.1 - 0.1 12.9 3.5 13 6.1 0.1 3.3 3 0 0 3 3 3 0 Apolipoprotein C4 DUF261 PF03196.13 PRP74178.1 - 0.11 12.6 0.0 33 4.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF261 DUF3857 PF12969.7 PRP74178.1 - 0.15 12.1 1.3 1e+02 2.9 0.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3857) rhaM PF05336.13 PRP74178.1 - 0.18 11.9 1.6 39 4.4 0.0 3.6 4 0 0 4 4 4 0 L-rhamnose mutarotase Corona_M PF01635.18 PRP74178.1 - 0.21 10.9 1.1 23 4.2 0.1 2.8 3 0 0 3 3 3 0 Coronavirus M matrix/glycoprotein DUF2256 PF10013.9 PRP74178.1 - 0.47 10.6 3.7 19 5.4 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) GRDP-like PF07173.12 PRP74178.1 - 3.3 8.4 9.1 30 5.2 0.3 4.4 3 2 2 5 5 5 0 Glycine-rich domain-containing protein-like Asp_protease_2 PF13650.6 PRP74179.1 - 0.046 14.4 0.0 0.15 12.7 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 PRP74179.1 - 0.072 13.7 0.0 0.6 10.7 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease AAA_15 PF13175.6 PRP74180.1 - 0.065 12.9 0.8 0.084 12.6 0.8 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2_4 PF13894.6 PRP74184.1 - 0.025 15.4 1.6 0.099 13.5 1.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1825 PF08855.10 PRP74185.1 - 0.043 13.7 0.7 0.051 13.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Glyco_hydr_30_2 PF14587.6 PRP74186.1 - 1.1e-24 87.8 4.1 1.1e-24 87.8 4.1 2.1 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Polyoma_coat2 PF00761.20 PRP74187.1 - 0.28 10.8 4.3 0.68 9.6 4.3 1.6 1 0 0 1 1 1 0 Polyomavirus coat protein DUF4813 PF16072.5 PRP74187.1 - 2 8.0 6.7 2.9 7.5 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Adeno_E3_15_3 PF03307.14 PRP74187.1 - 2.8 7.9 6.9 0.22 11.5 1.1 2.2 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region ADAM_CR PF08516.12 PRP74188.1 - 0.022 15.2 1.4 0.061 13.7 1.4 1.8 1 0 0 1 1 1 0 ADAM cysteine-rich Statherin PF03875.13 PRP74190.1 - 0.19 11.9 0.1 7.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Statherin zf-C3HC4_2 PF13923.6 PRP74191.1 - 1.6e-08 34.3 12.7 3.7e-08 33.1 12.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP74191.1 - 2.7e-08 33.6 11.9 4.5e-08 32.8 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP74191.1 - 1.1e-06 28.9 11.7 1.8e-06 28.2 11.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP74191.1 - 2.3e-05 24.2 13.8 3.5e-05 23.6 13.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP74191.1 - 3.5e-05 23.7 10.1 6.9e-05 22.7 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain RAWUL PF16207.5 PRP74191.1 - 0.00017 22.2 0.0 0.00064 20.3 0.0 1.9 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_4 PF15227.6 PRP74191.1 - 0.00044 20.3 7.9 0.00092 19.3 7.9 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PRP74191.1 - 0.00053 20.0 12.0 0.0011 18.9 12.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PRP74191.1 - 0.0011 19.2 6.2 0.0025 18.0 6.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 PRP74191.1 - 0.0024 17.6 6.7 0.0052 16.6 6.7 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 PRP74191.1 - 0.011 15.6 8.0 0.044 13.7 8.0 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 PRP74191.1 - 0.2 11.8 4.7 0.33 11.0 4.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 PRP74191.1 - 0.22 11.3 9.3 0.52 10.1 9.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 PRP74191.1 - 4.1 7.4 11.1 16 5.5 9.1 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rotamase_3 PF13616.6 PRP74192.1 - 1.3e-20 74.0 0.0 2.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 PRP74192.1 - 2.9e-16 60.2 0.0 7.7e-16 58.9 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 PRP74192.1 - 0.00016 22.5 0.0 0.00025 21.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain FAD_binding_3 PF01494.19 PRP74193.1 - 3.5e-09 36.4 0.0 5.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GRIP PF01465.20 PRP74194.1 - 1.6e-12 47.1 0.1 5.3e-12 45.4 0.1 2.0 1 0 0 1 1 1 1 GRIP domain Snapin_Pallidin PF14712.6 PRP74194.1 - 5.1e-05 23.6 4.8 5.1e-05 23.6 4.8 9.5 5 2 4 10 10 10 2 Snapin/Pallidin Laminin_G_3 PF13385.6 PRP74196.1 - 9.8e-14 51.8 3.3 9.8e-14 51.8 3.3 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 PRP74196.1 - 0.014 15.1 0.2 0.043 13.5 0.2 1.7 1 1 0 1 1 1 0 Pentaxin family HepII_C PF18675.1 PRP74196.1 - 0.032 14.3 0.8 1.3 9.1 0.2 2.7 2 0 0 2 2 2 0 Heparinase II C-terminal domain DNA_pol_B_2 PF03175.13 PRP74201.1 - 0.0022 16.9 0.1 0.003 16.5 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral AAA_lid_11 PF18198.1 PRP74201.1 - 0.054 13.3 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Asp_protease_2 PF13650.6 PRP74204.1 - 6.1e-06 26.8 0.0 1.1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PRP74204.1 - 0.00023 21.6 0.0 0.00041 20.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_2 PF13696.6 PRP74204.1 - 0.023 14.5 2.4 0.023 14.5 2.4 1.9 3 0 0 3 3 3 0 Zinc knuckle RVP PF00077.20 PRP74204.1 - 0.07 13.4 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease RVP_2 PF08284.11 PRP74204.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease eIF3g PF12353.8 PRP74204.1 - 0.12 12.8 1.3 0.19 12.1 1.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G MHYT PF03707.16 PRP74204.1 - 0.64 10.2 5.2 0.14 12.3 1.5 1.7 1 1 1 2 2 2 0 Bacterial signalling protein N terminal repeat zf-CCHC PF00098.23 PRP74204.1 - 0.79 9.9 5.2 3.4 7.9 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle Ank_5 PF13857.6 PRP74205.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DDE_Tnp_4 PF13359.6 PRP74207.1 - 2.3e-24 85.9 0.0 2.7e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP74207.1 - 7.5e-05 22.5 0.0 0.00012 21.8 0.0 1.3 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.6 PRP74207.1 - 0.1 13.0 0.1 0.25 11.8 0.1 1.7 1 1 0 1 1 1 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 PRP74208.1 - 2.1e-18 66.5 0.0 2.5e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RasGEF PF00617.19 PRP74212.1 - 2e-40 138.9 1.4 4.3e-40 137.8 1.4 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP74212.1 - 9.5e-15 54.7 1.6 3.2e-14 53.0 0.6 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif DDE_3 PF13358.6 PRP74213.1 - 1e-07 31.8 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease PWWP PF00855.17 PRP74216.1 - 1.4e-17 63.9 2.4 1.4e-17 63.9 2.4 2.2 3 0 0 3 3 3 1 PWWP domain SOBP PF15279.6 PRP74216.1 - 0.17 12.5 11.7 0.27 11.8 11.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Cupin_5 PF06172.11 PRP74219.1 - 2.5e-32 112.0 0.0 3.1e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Pkinase_Tyr PF07714.17 PRP74221.1 - 2e-31 109.2 1.6 3.5e-31 108.4 1.6 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74221.1 - 1.4e-22 80.3 1.1 2.9e-22 79.3 1.1 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP74221.1 - 4.4e-19 68.3 46.9 8.8e-06 26.0 5.6 6.7 4 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP74221.1 - 1.7e-16 59.7 39.1 5.2e-07 29.3 7.6 4.7 2 2 2 4 4 4 4 Leucine rich repeat GPS PF01825.21 PRP74221.1 - 6.7e-10 39.3 4.2 1.9e-09 37.9 4.2 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP74221.1 - 1.8e-05 24.6 28.4 2.1 9.2 0.3 9.4 9 0 0 9 9 9 3 Leucine Rich Repeat Kinase-like PF14531.6 PRP74221.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like VEGFR-2_TMD PF17988.1 PRP74221.1 - 0.066 12.7 0.6 0.16 11.4 0.6 1.6 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain NARP1 PF12569.8 PRP74221.1 - 0.88 8.4 11.2 1.4 7.8 11.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TGS PF02824.21 PRP74223.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 TGS domain COMM_domain PF07258.14 PRP74224.1 - 5.8e-12 45.6 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 COMM domain AidB_N PF18158.1 PRP74225.1 - 1.6e-29 102.8 0.0 3e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 PRP74225.1 - 2e-23 83.3 0.1 5.8e-23 81.8 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PRP74225.1 - 7.3e-14 51.7 0.1 1.3e-13 51.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PRP74225.1 - 1.4e-06 28.6 0.0 3.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PRP74225.1 - 0.003 18.2 0.0 0.0085 16.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain PDR_CDR PF06422.12 PRP74225.1 - 0.02 14.8 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 CDR ABC transporter Cytochrom_C1 PF02167.15 PRP74227.1 - 4.2e-94 314.4 0.0 4.8e-94 314.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 PRP74227.1 - 0.00093 19.5 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 PRP74227.1 - 0.21 12.8 0.3 0.46 11.7 0.3 1.7 1 1 0 1 1 1 0 Cytochrome c Pkinase PF00069.25 PRP74232.1 - 1.5e-65 221.2 0.0 2.5e-65 220.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74232.1 - 1.5e-46 158.8 0.0 2.5e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP74232.1 - 2.7e-05 23.2 0.0 6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP74232.1 - 0.0032 16.9 0.1 0.012 14.9 0.0 1.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PRP74232.1 - 0.0047 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP74232.1 - 0.0085 15.5 0.1 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_10 PF15411.6 PRP74232.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain HNH_2 PF13391.6 PRP74233.1 - 0.035 14.2 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 HNH endonuclease HTH_Tnp_4 PF13613.6 PRP74235.1 - 0.004 16.9 0.1 0.0079 15.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Cg6151-P PF10233.9 PRP74235.1 - 0.023 15.0 0.1 0.051 13.9 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P DUF1189 PF06691.11 PRP74235.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) AIF_C PF14721.6 PRP74238.1 - 0.1 12.9 4.0 0.99 9.8 4.0 2.0 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pkinase_Tyr PF07714.17 PRP74242.1 - 3e-31 108.7 0.0 5e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74242.1 - 1.1e-23 84.0 0.0 2.2e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 PRP74242.1 - 0.062 14.2 0.4 0.15 12.9 0.4 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PRP74242.1 - 0.59 10.0 5.5 0.078 12.9 0.2 2.3 2 0 0 2 2 2 0 TMEM154 protein family DUF347 PF03988.12 PRP74242.1 - 1.6 9.0 5.6 0.8 9.9 2.1 2.3 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) GerPB PF10803.8 PRP74242.1 - 2.9 8.0 6.5 1.5 8.9 0.2 3.7 3 0 0 3 3 3 0 Spore germination GerPB ResIII PF04851.15 PRP74244.1 - 4.8e-17 62.5 0.5 2.4e-16 60.2 0.1 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP74244.1 - 3.8e-16 59.4 0.0 1.6e-15 57.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP74244.1 - 5.6e-12 45.8 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 PRP74244.1 - 1e-07 31.9 0.2 2.3e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase RIG-I_C-RD PF11648.8 PRP74244.1 - 0.015 15.5 5.8 1.9 8.7 0.2 3.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Flavi_DEAD PF07652.14 PRP74244.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 PRP74244.1 - 0.2 12.0 1.5 0.6 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain Yippee-Mis18 PF03226.14 PRP74244.1 - 5.6 7.2 9.5 7.8 6.8 1.4 2.7 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly 2OG-FeII_Oxy_2 PF13532.6 PRP74245.1 - 2.2e-40 139.0 0.0 2.7e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRP3 PF08572.10 PRP74246.1 - 2.8e-54 184.2 9.1 2.8e-54 184.2 9.1 1.7 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 PRP74246.1 - 2.9e-37 128.0 2.6 2.9e-37 128.0 2.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) PIG-L PF02585.17 PRP74247.1 - 2e-22 80.2 0.1 2.6e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Ribosomal_S3_C PF00189.20 PRP74248.1 - 1.2e-23 83.4 0.1 5e-23 81.4 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 PRP74248.1 - 7.8e-12 44.9 0.4 1.2e-11 44.2 0.4 1.3 1 0 0 1 1 1 1 KH domain zf-C3HC4_3 PF13920.6 PRP74251.1 - 0.00047 20.0 3.3 0.0065 16.3 3.2 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP74251.1 - 0.0087 16.0 0.8 0.032 14.2 0.5 2.2 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PRP74251.1 - 0.044 13.7 4.5 0.15 12.0 4.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PRP74251.1 - 0.51 10.7 4.3 2.5 8.5 4.3 2.3 1 1 0 1 1 1 0 Ring finger domain HNH_2 PF13391.6 PRP74254.1 - 0.014 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease Histone PF00125.24 PRP74257.1 - 1.3e-05 25.5 0.0 2.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 HMG_box_2 PF09011.10 PRP74257.1 - 0.00024 21.6 0.5 0.76 10.4 0.1 2.4 2 0 0 2 2 2 2 HMG-box domain Esterase_phd PF10503.9 PRP74257.1 - 0.079 12.4 0.0 6.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF5310 PF17237.2 PRP74257.1 - 1.3 8.9 7.5 4.2 7.3 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5310) PH PF00169.29 PRP74258.1 - 6.7e-23 81.2 0.0 2.7e-11 43.9 0.1 2.7 2 0 0 2 2 2 2 PH domain C2 PF00168.30 PRP74258.1 - 3.2e-15 56.3 0.0 9.7e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 C2 domain TPR_2 PF07719.17 PRP74258.1 - 2.7e-14 52.1 0.3 0.0023 17.9 0.5 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP74258.1 - 1.5e-13 49.9 6.9 0.00088 19.0 0.9 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP74258.1 - 9.3e-13 47.3 4.4 0.056 13.7 0.1 5.5 7 0 0 7 7 4 4 Tetratricopeptide repeat PH_3 PF14593.6 PRP74258.1 - 1.2e-08 35.0 1.3 7.6e-07 29.2 0.8 2.5 2 0 0 2 2 2 1 PH domain TPR_14 PF13428.6 PRP74258.1 - 1.3e-05 25.6 0.0 11 7.1 0.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP74258.1 - 7.6e-05 23.1 0.0 1 9.9 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat PH_6 PF15406.6 PRP74258.1 - 0.00013 22.2 0.0 0.00055 20.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_16 PF13432.6 PRP74258.1 - 0.00027 21.5 0.0 3.1 8.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP74258.1 - 0.0017 18.9 0.5 11 6.9 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP74258.1 - 0.0019 17.8 1.4 2.9 7.6 0.1 3.8 3 0 0 3 3 3 1 TPR repeat PH_8 PF15409.6 PRP74258.1 - 0.0048 17.1 0.4 0.047 14.0 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 PRP74258.1 - 0.0051 17.2 5.9 0.73 10.3 0.5 4.1 2 2 1 3 3 3 1 Pleckstrin homology domain ANAPC3 PF12895.7 PRP74258.1 - 0.017 15.3 1.9 2.1 8.6 1.0 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PH_13 PF16652.5 PRP74258.1 - 0.039 13.8 1.8 0.51 10.1 0.2 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2742 PF10888.8 PRP74258.1 - 0.061 13.6 0.1 2.8 8.3 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2742) TPR_17 PF13431.6 PRP74258.1 - 5.5 7.6 5.7 6.6 7.3 0.9 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat CLPTM1 PF05602.12 PRP74259.1 - 2.1e-142 475.2 7.1 3.7e-142 474.3 7.1 1.4 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 PRP74259.1 - 0.00053 19.7 3.5 0.077 12.8 0.4 2.8 2 0 0 2 2 2 2 PQ loop repeat LrgB PF04172.16 PRP74259.1 - 0.059 12.9 0.3 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 LrgB-like family DUF1097 PF06496.11 PRP74259.1 - 0.063 13.4 1.1 0.2 11.8 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) IF4E PF01652.18 PRP74260.1 - 7.6e-44 149.3 4.6 1.4e-43 148.5 4.6 1.4 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E MBOAT PF03062.19 PRP74261.1 - 1.7e-44 152.6 8.2 3.1e-44 151.8 8.2 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family RabGAP-TBC PF00566.18 PRP74262.1 - 7.9e-26 91.0 5.6 1.7e-23 83.4 4.1 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain LOH1CR12 PF10158.9 PRP74262.1 - 1.9e-09 37.6 2.7 4.4e-09 36.5 2.7 1.5 1 0 0 1 1 1 1 Tumour suppressor protein BROMI PF14961.6 PRP74262.1 - 0.0051 14.3 0.2 0.0051 14.3 0.2 1.4 2 0 0 2 2 2 1 Broad-minded protein Cep57_CLD_2 PF14197.6 PRP74262.1 - 0.082 13.0 0.2 0.22 11.6 0.2 1.7 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Guanylate_kin PF00625.21 PRP74264.1 - 2.7e-58 196.6 0.0 3.4e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 PRP74264.1 - 2.8e-05 24.1 0.0 4.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 PRP74264.1 - 0.00018 22.0 0.0 0.00034 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RIIa PF02197.17 PRP74264.1 - 0.0002 20.9 0.4 0.00063 19.4 0.1 2.0 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit NTPase_1 PF03266.15 PRP74264.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_18 PF13238.6 PRP74264.1 - 0.0011 19.5 0.1 0.0025 18.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PRP74264.1 - 0.0014 18.9 0.0 0.0059 16.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PRP74264.1 - 0.0024 17.9 0.0 0.0082 16.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 PRP74264.1 - 0.0031 17.1 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 PRP74264.1 - 0.0064 17.0 0.0 0.011 16.3 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 PRP74264.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 PRP74264.1 - 0.018 14.8 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 PRP74264.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 PRP74264.1 - 0.044 14.2 0.1 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PRP74264.1 - 0.068 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Bombinin PF05298.11 PRP74264.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Bombinin AAA_14 PF13173.6 PRP74264.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PRP74264.1 - 0.076 13.0 0.0 0.99 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PRP74264.1 - 0.13 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 PRP74264.1 - 0.16 11.2 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain BCS1_N PF08740.11 PRP74265.1 - 3.7e-28 98.8 2.9 8e-28 97.7 2.9 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 PRP74265.1 - 7e-16 58.9 0.0 1.6e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP74265.1 - 0.001 19.1 0.2 1.2 9.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 PRP74265.1 - 0.0052 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP74265.1 - 0.017 15.5 0.0 0.093 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PRP74265.1 - 0.027 15.0 0.0 0.2 12.2 0.0 2.5 2 1 0 2 2 2 0 ABC transporter DUF815 PF05673.13 PRP74265.1 - 0.031 13.4 0.0 0.073 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 PRP74265.1 - 0.043 13.7 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 PRP74265.1 - 0.12 12.8 0.1 0.49 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 PRP74265.1 - 0.18 11.6 8.4 3.2 7.5 0.0 3.0 2 1 0 3 3 3 0 AAA domain CTC1_2 PF15491.6 PRP74266.1 - 7.7e-05 22.1 0.6 0.0003 20.2 0.2 2.2 2 1 0 2 2 2 1 CST, telomere maintenance, complex subunit CTC1 CTC1 PF15489.6 PRP74266.1 - 0.0012 16.5 0.2 0.0028 15.3 0.1 1.7 2 0 0 2 2 2 1 CST, telomere maintenance, complex subunit CTC1 HNOBA PF07701.14 PRP74266.1 - 0.05 13.0 1.7 0.14 11.6 0.0 2.3 2 1 0 2 2 2 0 Heme NO binding associated Imm31 PF15591.6 PRP74266.1 - 0.051 13.4 0.2 1.2 9.1 0.1 2.7 2 0 0 2 2 2 0 Immunity protein 31 SH3_1 PF00018.28 PRP74267.1 - 2e-13 49.7 0.1 4.7e-13 48.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP74267.1 - 5.5e-12 45.4 0.2 1.6e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 PRP74267.1 - 8.3e-10 38.2 0.0 2.2e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Lebercilin PF15619.6 PRP74267.1 - 4.4e-08 33.0 25.2 4.4e-08 33.0 25.2 2.4 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Myc_N PF01056.18 PRP74267.1 - 0.0016 18.4 8.4 0.0016 18.4 8.4 3.4 3 1 0 3 3 3 1 Myc amino-terminal region DUF3614 PF12267.8 PRP74267.1 - 1.2 9.6 15.0 0.019 15.5 3.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) Pkinase_Tyr PF07714.17 PRP74268.1 - 1.2e-50 172.3 0.0 1.8e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74268.1 - 3.3e-49 167.6 0.0 5.6e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_L1 PF00687.21 PRP74268.1 - 1.7e-36 125.9 1.7 2.8e-36 125.2 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SH2 PF00017.24 PRP74268.1 - 7.2e-10 38.8 0.0 1.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 PRP74268.1 - 0.00025 21.5 1.2 0.00025 21.5 1.2 2.8 2 1 0 2 2 2 1 PH domain APH PF01636.23 PRP74268.1 - 0.00034 20.6 0.1 0.16 11.9 0.0 3.4 3 1 1 4 4 4 1 Phosphotransferase enzyme family Cbl_N2 PF02761.14 PRP74268.1 - 0.0056 17.4 1.1 0.02 15.6 0.1 2.4 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain PH_11 PF15413.6 PRP74268.1 - 0.12 12.8 1.9 0.64 10.5 1.1 2.6 1 1 1 2 2 2 0 Pleckstrin homology domain Ribosomal_S7 PF00177.21 PRP74269.1 - 3.6e-37 127.3 1.6 4.5e-37 127.0 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Peptidase_C47 PF05543.13 PRP74269.1 - 0.062 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Staphopain peptidase C47 TPT PF03151.16 PRP74270.1 - 2.4e-12 46.8 18.2 2.9e-12 46.5 18.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PRP74270.1 - 2.2e-06 27.9 9.6 2.2e-06 27.9 9.6 2.3 2 0 0 2 2 2 1 EamA-like transporter family Flavi_NS4A PF01350.17 PRP74270.1 - 0.26 11.2 3.9 0.1 12.5 1.0 1.9 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A UPF0121 PF03661.13 PRP74271.1 - 0.091 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) DENN PF02141.21 PRP74272.1 - 4.7e-34 118.0 5.7 4.7e-34 118.0 5.7 2.9 2 1 0 2 2 2 1 DENN (AEX-3) domain DUF547 PF04784.14 PRP74272.1 - 8.7e-25 87.1 0.0 1.8e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF547 uDENN PF03456.18 PRP74272.1 - 0.0015 19.2 0.0 0.018 15.8 0.0 2.8 2 1 1 3 3 3 1 uDENN domain dDENN PF03455.19 PRP74272.1 - 0.0017 18.3 1.4 0.0051 16.8 1.4 1.9 1 0 0 1 1 1 1 dDENN domain GRAM PF02893.20 PRP74272.1 - 0.028 14.3 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 GRAM domain UPF0054 PF02130.17 PRP74273.1 - 1.3e-27 96.1 0.0 1.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 RNA_pol_Rpb4 PF03874.16 PRP74274.1 - 2.1e-09 37.8 7.5 1.7e-08 34.8 7.5 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb4 Apc15p PF05841.11 PRP74274.1 - 0.2 12.5 5.0 0.39 11.5 5.0 1.5 1 1 0 1 1 1 0 Apc15p protein Sec62 PF03839.16 PRP74274.1 - 0.83 9.1 5.2 1 8.8 5.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 PRP74274.1 - 8.1 5.1 5.2 9.5 4.9 5.2 1.1 1 0 0 1 1 1 0 Presenilin CLU PF13236.6 PRP74275.1 - 2.9e-71 239.8 0.0 5.7e-71 238.9 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP74275.1 - 1.4e-43 149.0 0.4 3.6e-43 147.6 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 PRP74275.1 - 2.5e-30 104.6 0.5 2.1e-11 43.9 0.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 PRP74275.1 - 9.6e-20 69.8 0.3 1.1e-06 28.3 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat CLU_N PF15044.6 PRP74275.1 - 5.2e-15 55.6 0.2 1.3e-14 54.3 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_1 PF00515.28 PRP74275.1 - 2.8e-10 39.5 2.2 0.17 11.7 0.4 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP74275.1 - 5.7e-10 38.5 0.3 0.09 12.9 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF727 PF05303.12 PRP74275.1 - 7.5e-06 26.0 0.0 6.7e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 PRP74275.1 - 2.3e-05 24.3 3.4 1.4 9.3 0.3 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP74275.1 - 0.00059 19.3 0.2 0.0011 18.5 0.2 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 PRP74275.1 - 0.24 11.5 0.7 7.4 6.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Mtp PF03821.16 PRP74279.1 - 0.088 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter RNase_H PF00075.24 PRP74281.1 - 0.014 15.6 0.1 0.032 14.4 0.1 1.7 1 0 0 1 1 1 0 RNase H zf-RRPl_C4 PF17026.5 PRP74281.1 - 0.14 12.3 2.0 0.23 11.6 0.2 2.3 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type SpecificRecomb PF10136.9 PRP74283.1 - 0.0033 15.8 0.0 0.005 15.2 0.0 1.2 1 0 0 1 1 1 1 Site-specific recombinase Rapsyn_N PF10579.9 PRP74285.1 - 0.016 15.3 1.3 0.024 14.7 1.3 1.4 1 1 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region YopE_N PF09020.10 PRP74287.1 - 0.047 13.9 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 YopE, N terminal RBD-FIP PF09457.10 PRP74288.1 - 1.1 9.2 7.4 2.1 8.3 1.3 3.7 2 0 0 2 2 2 0 FIP domain Cas_Csa4 PF09703.10 PRP74288.1 - 3.1 7.0 10.3 0.25 10.6 3.4 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa4) Terminase_3C PF17288.2 PRP74288.1 - 5.4 7.4 8.5 7.7 6.9 6.6 2.3 1 1 1 2 2 2 0 Terminase RNAseH like domain Pkinase PF00069.25 PRP74291.1 - 4.6e-51 173.7 0.0 1.7e-50 171.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74291.1 - 1.2e-25 90.3 0.0 1.4e-24 86.8 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.20 PRP74291.1 - 3e-07 30.3 0.0 9.5e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain FTA2 PF13095.6 PRP74291.1 - 0.0041 16.8 0.0 2.5 7.7 0.0 2.6 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 OrsD PF12013.8 PRP74291.1 - 0.067 13.6 3.5 0.35 11.3 0.2 2.6 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Pkinase_Tyr PF07714.17 PRP74292.1 - 7.3e-43 146.7 0.0 1.1e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74292.1 - 1.7e-31 109.5 0.0 5.4e-30 104.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain GPS PF01825.21 PRP74292.1 - 0.0036 17.8 1.1 0.0098 16.4 1.1 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif CBM_4_9 PF02018.17 PRP74292.1 - 0.033 14.4 0.1 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding domain EphA2_TM PF14575.6 PRP74292.1 - 0.13 13.2 0.2 0.27 12.2 0.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PRP74292.1 - 0.15 12.0 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family Pkinase_Tyr PF07714.17 PRP74293.1 - 4.1e-42 144.3 0.0 5.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74293.1 - 4.9e-32 111.3 0.0 7.4e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP74293.1 - 0.0041 17.6 0.2 0.0091 16.5 0.2 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif MGC-24 PF05283.11 PRP74293.1 - 0.074 13.5 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pkinase_Tyr PF07714.17 PRP74294.1 - 7.1e-41 140.2 0.0 1.1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74294.1 - 5.2e-35 121.1 0.0 2.6e-34 118.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain GPS PF01825.21 PRP74294.1 - 0.0067 16.9 1.9 0.011 16.3 0.2 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP74294.1 - 0.09 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 PRP74294.1 - 0.11 12.0 0.5 0.2 11.2 0.5 1.3 1 0 0 1 1 1 0 RIO1 family Sec7 PF01369.20 PRP74295.1 - 1.4e-47 161.7 0.1 2.5e-47 160.9 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain DEP PF00610.21 PRP74295.1 - 8.7e-14 51.3 0.2 4.6e-13 49.0 0.3 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ras PF00071.22 PRP74295.1 - 2.3e-07 30.5 0.3 5e-06 26.2 0.1 2.6 2 1 0 2 2 2 1 Ras family PH PF00169.29 PRP74295.1 - 9.2e-05 22.9 0.0 0.031 14.8 0.0 2.7 2 0 0 2 2 2 2 PH domain BCS1_N PF08740.11 PRP74295.1 - 0.014 15.4 0.2 0.029 14.3 0.2 1.5 1 0 0 1 1 1 0 BCS1 N terminal F-box-like PF12937.7 PRP74296.1 - 7.5e-08 32.1 0.3 7.5e-08 32.1 0.3 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 PRP74296.1 - 2e-05 24.4 0.4 2e-05 24.4 0.4 2.6 3 0 0 3 3 3 1 F-box domain HhH-GPD PF00730.25 PRP74296.1 - 0.0038 17.7 0.0 0.0063 17.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PAS PF00989.25 PRP74297.1 - 0.0078 16.2 0.2 0.099 12.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold Toxin-JAB1 PF15659.6 PRP74298.1 - 0.051 13.9 0.0 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 JAB-like toxin 1 TAF8_C PF10406.9 PRP74299.1 - 9.7e-15 54.9 0.9 9.7e-15 54.9 0.9 2.5 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 PRP74299.1 - 1.5e-09 37.7 0.2 2.6e-09 36.9 0.2 1.4 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 PRP74299.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Histone-fold protein CAML PF14963.6 PRP74299.1 - 3.2 7.8 6.2 4.9 7.2 6.2 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CH_2 PF06294.11 PRP74300.1 - 6.2e-31 106.4 0.1 1.6e-30 105.0 0.0 1.7 1 1 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PRP74300.1 - 7.2e-15 54.6 0.0 1.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 PRP74300.1 - 0.033 14.4 0.5 0.11 12.7 0.1 2.1 2 1 1 3 3 3 0 Calponin homology (CH) domain SPATA24 PF15175.6 PRP74300.1 - 0.055 13.4 0.6 0.055 13.4 0.6 1.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 MAP70 PF07058.11 PRP74300.1 - 0.058 12.1 0.5 0.078 11.7 0.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 TMF_DNA_bd PF12329.8 PRP74300.1 - 0.097 12.7 3.8 0.22 11.5 3.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding XLF PF09302.11 PRP74300.1 - 0.12 12.5 2.0 0.63 10.2 0.1 2.4 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component ATP_bind_1 PF03029.17 PRP74301.1 - 4e-79 265.8 0.1 7.4e-79 264.9 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 PRP74301.1 - 0.0033 17.6 0.2 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP74301.1 - 0.0065 16.9 1.2 0.19 12.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain KTI12 PF08433.10 PRP74301.1 - 0.0074 15.8 0.0 0.019 14.4 0.0 1.7 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CbiA PF01656.23 PRP74301.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 PRP74301.1 - 0.037 13.7 0.2 0.17 11.6 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 PRP74301.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 PRP74301.1 - 0.15 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 PRP74301.1 - 0.17 11.6 4.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 PRP74301.1 - 0.18 11.4 0.0 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PAP2 PF01569.21 PRP74302.1 - 2.7e-19 69.3 2.7 2.7e-19 69.3 2.7 2.9 3 1 0 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.6 PRP74302.1 - 2.9e-09 36.9 9.8 2.9e-09 36.9 9.8 4.2 2 2 1 4 4 4 1 PAP2 superfamily PAP2_C PF14360.6 PRP74302.1 - 0.00033 21.1 3.2 0.00033 21.1 3.2 3.7 4 1 1 5 5 5 1 PAP2 superfamily C-terminal Gly_transf_sug PF04488.15 PRP74303.1 - 0.00084 19.9 0.1 0.0017 18.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ribonuc_L-PSP PF01042.21 PRP74304.1 - 7.4e-43 145.4 0.9 8.2e-43 145.3 0.9 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RPN13_C PF16550.5 PRP74304.1 - 0.083 13.1 0.0 0.52 10.5 0.0 2.0 1 1 1 2 2 2 0 UCH-binding domain 2-Hacid_dh_C PF02826.19 PRP74305.1 - 4.7e-52 175.9 0.0 1.2e-51 174.6 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PRP74305.1 - 3e-28 98.1 0.0 3.5e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 PRP74305.1 - 1.2e-06 28.2 0.1 3.2e-06 26.8 0.1 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 PRP74305.1 - 5.4e-05 23.4 0.2 9.6e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 PRP74305.1 - 0.0084 16.2 0.3 0.022 14.8 0.3 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 PRP74305.1 - 0.026 14.6 0.0 0.085 12.9 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase PALP PF00291.25 PRP74305.1 - 0.035 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DSBA PF01323.20 PRP74306.1 - 3.4e-39 134.6 0.0 4e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 PRP74306.1 - 0.00051 20.0 0.0 0.0069 16.4 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin domain RasGEF PF00617.19 PRP74307.1 - 3.6e-40 138.1 1.1 2.2e-39 135.5 1.0 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP74307.1 - 0.015 15.6 0.7 0.015 15.6 0.7 2.6 3 0 0 3 3 3 0 RasGEF N-terminal motif MORN PF02493.20 PRP74309.1 - 4.4e-10 38.8 26.9 0.003 17.4 0.6 6.3 7 0 0 7 7 7 4 MORN repeat C9orf72-like PF15019.6 PRP74309.1 - 0.012 15.2 0.9 0.027 14.0 0.9 1.6 1 0 0 1 1 1 0 C9orf72-like protein family Chromo PF00385.24 PRP74309.1 - 0.026 14.4 0.6 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain SGL PF08450.12 PRP74309.1 - 0.032 13.8 1.1 0.06 12.9 1.1 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region UpxZ PF06603.11 PRP74309.1 - 0.089 13.1 0.6 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 UpxZ family of transcription anti-terminator antagonists Sina PF03145.16 PRP74310.1 - 3.6e-08 33.6 10.6 6.1e-05 23.1 1.4 2.9 2 1 1 3 3 3 2 Seven in absentia protein family Alanine_zipper PF11839.8 PRP74310.1 - 0.027 14.8 2.9 0.027 14.8 2.9 1.7 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Tropomyosin PF00261.20 PRP74310.1 - 3.4 7.0 18.0 0.74 9.1 4.7 2.2 2 0 0 2 2 2 0 Tropomyosin Tropomyosin_1 PF12718.7 PRP74310.1 - 6.7 6.9 15.3 0.84 9.8 5.3 2.3 2 0 0 2 2 2 0 Tropomyosin like X8 PF07983.13 PRP74311.1 - 1.6e-17 63.9 19.6 2e-09 38.0 6.0 3.2 3 1 0 3 3 3 2 X8 domain Glyco_hydro_17 PF00332.18 PRP74311.1 - 2.2e-06 27.5 0.2 2.4e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 zf-CHY PF05495.12 PRP74311.1 - 1.1 9.9 8.9 0.47 11.0 1.9 2.4 2 0 0 2 2 2 0 CHY zinc finger DnaJ PF00226.31 PRP74312.1 - 1.1e-19 70.3 0.3 2.5e-19 69.2 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 PRP74312.1 - 0.00062 19.7 1.7 0.00077 19.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP74312.1 - 0.0049 17.1 0.2 0.012 15.9 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP74312.1 - 0.0072 16.1 0.3 0.026 14.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP74312.1 - 0.013 15.5 0.1 0.037 14.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP74312.1 - 0.047 14.5 0.4 0.16 12.9 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP74312.1 - 0.089 13.0 0.1 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF5638 PF18688.1 PRP74312.1 - 0.1 12.9 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5638) TPR_10 PF13374.6 PRP74312.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat FH2 PF02181.23 PRP74313.1 - 5.8e-92 308.7 6.0 5.8e-92 308.7 6.0 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Pkinase_Tyr PF07714.17 PRP74313.1 - 3.1e-78 262.6 0.2 5e-78 262.0 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74313.1 - 1.3e-49 168.9 0.1 2.8e-49 167.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Drf_FH3 PF06367.16 PRP74313.1 - 4e-22 78.8 9.0 8.2e-22 77.8 8.4 1.9 1 1 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP74313.1 - 0.00034 20.2 0.1 0.00086 18.9 0.1 1.7 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Kinase-like PF14531.6 PRP74313.1 - 0.0046 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Podoplanin PF05808.11 PRP74313.1 - 0.021 14.9 2.0 0.061 13.4 2.0 1.8 1 0 0 1 1 1 0 Podoplanin Amnionless PF14828.6 PRP74313.1 - 0.024 13.5 0.1 0.065 12.1 0.0 1.7 2 0 0 2 2 2 0 Amnionless Pkinase_fungal PF17667.1 PRP74313.1 - 0.12 11.1 2.4 0.098 11.4 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase MtrF PF09472.10 PRP74313.1 - 0.24 10.8 2.5 0.58 9.6 2.5 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syndecan PF01034.20 PRP74313.1 - 0.32 10.9 2.1 0.75 9.7 2.1 1.6 1 0 0 1 1 1 0 Syndecan domain Chlam_PMP PF02415.17 PRP74313.1 - 0.57 10.8 0.0 0.57 10.8 0.0 12.3 11 2 0 11 11 10 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat APH PF01636.23 PRP74313.1 - 6.1 6.7 5.2 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mtp PF03821.16 PRP74314.1 - 0.0059 16.2 2.0 0.38 10.3 0.2 2.2 2 0 0 2 2 2 2 Golgi 4-transmembrane spanning transporter DUF3763 PF12592.8 PRP74314.1 - 0.12 12.5 0.0 23 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) SpoVAC_SpoVAEB PF03862.13 PRP74316.1 - 0.076 13.3 0.1 0.082 13.2 0.1 1.0 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein UQ_con PF00179.26 PRP74317.1 - 1.7e-26 92.5 0.0 4.1e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Leo1 PF04004.13 PRP74317.1 - 0.76 9.6 4.5 1 9.2 0.1 2.6 2 0 0 2 2 2 0 Leo1-like protein LRR_8 PF13855.6 PRP74318.1 - 2.4e-16 59.2 43.7 6e-08 32.3 8.0 4.8 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 PRP74318.1 - 1.4e-08 34.9 44.6 0.00012 22.4 8.2 6.1 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP74318.1 - 1.2 9.3 25.3 6.5 7.1 0.2 5.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.6 PRP74318.1 - 1.4 8.4 3.8 2.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeat Pkinase_Tyr PF07714.17 PRP74319.1 - 4.3e-31 108.1 2.8 2.3e-18 66.4 0.1 3.1 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 PRP74319.1 - 2e-24 85.1 52.1 2.3e-10 40.1 10.7 6.7 4 1 3 7 7 7 6 Leucine rich repeat Pkinase PF00069.25 PRP74319.1 - 3.3e-24 85.7 2.4 1.7e-14 53.8 0.0 3.3 1 1 1 2 2 2 2 Protein kinase domain LRR_4 PF12799.7 PRP74319.1 - 5e-17 61.7 73.4 7.4e-06 26.2 8.5 9.6 6 2 5 12 12 12 8 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP74319.1 - 6.1e-11 42.7 1.4 2e-10 41.0 1.4 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif TMEM154 PF15102.6 PRP74319.1 - 0.12 12.3 0.7 0.25 11.3 0.7 1.5 1 0 0 1 1 1 0 TMEM154 protein family PMP1_2 PF08114.11 PRP74319.1 - 0.16 11.7 4.9 0.099 12.4 2.0 2.1 2 0 0 2 2 2 0 ATPase proteolipid family LRR_1 PF00560.33 PRP74319.1 - 6.8 7.7 56.7 0.21 12.3 1.5 12.7 12 2 0 12 12 12 0 Leucine Rich Repeat MRG PF05712.13 PRP74321.1 - 3.1e-18 65.8 2.6 7.6e-18 64.5 2.6 1.6 1 1 0 1 1 1 1 MRG Pkinase_Tyr PF07714.17 PRP74321.1 - 1e-10 41.4 0.1 3.1e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Tudor-knot PF11717.8 PRP74321.1 - 7.5e-09 35.4 0.7 2e-08 34.0 0.7 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pkinase PF00069.25 PRP74321.1 - 2.3e-07 30.5 0.0 4.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP74321.1 - 7.6e-06 25.6 3.4 9e-05 22.2 2.3 2.9 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PRP74321.1 - 0.003 17.9 4.6 0.003 17.9 4.6 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) Chromo PF00385.24 PRP74321.1 - 0.025 14.5 0.4 0.066 13.1 0.4 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain LRR_1 PF00560.33 PRP74321.1 - 0.044 14.3 6.8 3.5 8.6 0.2 3.8 2 1 0 2 2 2 0 Leucine Rich Repeat NUDIX PF00293.28 PRP74322.1 - 3.7e-14 52.9 0.1 4.5e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PRP74322.1 - 0.0028 17.6 0.2 0.013 15.4 0.2 1.9 1 1 0 1 1 1 1 NUDIX domain Gla PF00594.20 PRP74322.1 - 0.042 14.1 0.5 0.082 13.1 0.5 1.4 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain ABC2_membrane PF01061.24 PRP74323.1 - 4e-48 163.6 21.1 4e-48 163.6 21.1 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PRP74323.1 - 1e-31 110.3 0.0 6.6e-17 62.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 PRP74323.1 - 6.1e-19 67.7 0.5 6.1e-19 67.7 0.5 3.1 2 1 0 2 2 2 1 CDR ABC transporter RsgA_GTPase PF03193.16 PRP74323.1 - 2.3e-07 30.9 0.1 0.00038 20.4 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane_3 PF12698.7 PRP74323.1 - 5.2e-07 29.1 14.6 5.2e-07 29.1 14.6 2.5 2 1 1 3 3 3 1 ABC-2 family transporter protein ABC_trans_N PF14510.6 PRP74323.1 - 6.7e-07 29.8 0.1 2.2e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 PRP74323.1 - 4.1e-06 26.4 0.1 0.0028 17.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP74323.1 - 1.1e-05 25.9 0.0 0.085 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 PRP74323.1 - 8.4e-05 21.9 0.0 0.021 14.1 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 PRP74323.1 - 0.00019 21.7 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PRP74323.1 - 0.00066 20.2 0.0 0.082 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PRP74323.1 - 0.00073 19.2 0.4 0.002 17.7 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PRP74323.1 - 0.0012 19.0 0.1 0.18 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PRP74323.1 - 0.0029 17.7 0.3 2.9 8.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 PRP74323.1 - 0.019 14.7 1.5 1.3 8.7 1.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 PRP74323.1 - 0.026 14.3 0.0 0.093 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PRP74323.1 - 0.028 14.9 1.5 0.5 10.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PRP74323.1 - 0.032 14.5 3.3 0.19 12.0 1.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 PRP74323.1 - 0.04 13.5 0.6 0.7 9.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 PRP74323.1 - 0.073 13.5 0.0 29 5.1 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 PRP74323.1 - 0.1 13.0 0.2 15 6.0 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PRP74323.1 - 0.11 12.5 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 PRP74323.1 - 0.15 12.1 0.3 2.1 8.4 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 PRP74323.1 - 0.24 11.1 1.7 23 4.7 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Dynamin_N PF00350.23 PRP74323.1 - 0.28 11.2 1.6 5 7.2 0.0 3.0 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.12 PRP74323.1 - 0.54 10.2 3.0 4.1 7.3 0.6 2.6 3 0 0 3 3 2 0 NACHT domain WW PF00397.26 PRP74324.1 - 1.2e-10 41.2 1.6 1.7e-10 40.8 1.6 1.2 1 0 0 1 1 1 1 WW domain DKCLD PF08068.12 PRP74325.1 - 3.4e-31 107.1 0.2 8.9e-30 102.5 0.3 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 PRP74325.1 - 3.1e-22 79.6 0.5 3.4e-19 69.7 0.5 3.7 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PRP74325.1 - 1.1e-20 73.5 0.8 2.1e-20 72.6 0.1 1.9 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 PRP74325.1 - 8.1e-19 67.4 1.1 1.8e-18 66.3 1.1 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 PRP74325.1 - 0.018 15.3 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain SAPS PF04499.15 PRP74325.1 - 5.2 5.7 11.9 8.1 5.1 11.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 PRP74325.1 - 8.4 6.6 16.3 16 5.7 16.3 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family PARP PF00644.20 PRP74326.1 - 5.4e-45 153.4 0.0 1.1e-44 152.4 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PRP74326.1 - 4.2e-23 81.9 0.1 1.7e-22 80.0 0.1 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Ank_4 PF13637.6 PRP74326.1 - 1.5e-14 54.1 1.6 0.0076 16.8 0.0 6.7 6 1 2 8 8 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP74326.1 - 1.1e-12 48.4 3.3 0.0017 18.9 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP74326.1 - 1.5e-10 41.1 0.6 0.0015 18.8 0.0 5.6 5 2 2 7 7 7 2 Ankyrin repeats (many copies) BRCT PF00533.26 PRP74326.1 - 1e-06 29.0 0.0 3.6e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ank_3 PF13606.6 PRP74326.1 - 1.3e-05 25.2 7.2 2.2 9.1 0.0 7.3 9 0 0 9 9 6 2 Ankyrin repeat Ank PF00023.30 PRP74326.1 - 2.6e-05 24.4 2.4 0.052 14.0 0.0 5.6 6 0 0 6 6 5 1 Ankyrin repeat BRCT_2 PF16589.5 PRP74326.1 - 6.1e-05 23.4 0.0 0.00025 21.4 0.0 2.1 2 0 0 2 2 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PRP74326.1 - 0.0037 17.2 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain YqhG PF11079.8 PRP74326.1 - 0.036 13.0 2.8 0.11 11.5 2.8 1.7 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function NapD PF03927.13 PRP74326.1 - 0.051 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 NapD protein Phage_CI_repr PF07022.13 PRP74326.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Fzo_mitofusin PF04799.13 PRP74326.1 - 0.23 11.0 1.4 0.76 9.3 1.4 1.8 1 0 0 1 1 1 0 fzo-like conserved region DUF3646 PF12362.8 PRP74326.1 - 2.8 8.3 5.2 0.49 10.7 0.8 2.0 2 0 0 2 2 1 0 DNA polymerase III gamma and tau subunits C terminal Ras PF00071.22 PRP74329.1 - 8.4e-08 32.0 0.0 5e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Ras family Arf PF00025.21 PRP74329.1 - 0.013 15.0 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 PRP74329.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DDE_Tnp_1_3 PF13612.6 PRP74329.1 - 0.081 12.9 0.3 0.24 11.4 0.3 1.7 1 0 0 1 1 1 0 Transposase DDE domain GTP_EFTU PF00009.27 PRP74329.1 - 0.11 12.0 0.1 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Phage_HK97_TLTM PF06120.11 PRP74329.1 - 0.33 10.1 5.2 0.43 9.7 0.2 2.4 1 1 1 2 2 2 0 Tail length tape measure protein DUF948 PF06103.11 PRP74329.1 - 0.53 10.6 3.4 11 6.4 0.0 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MMM1 PF10296.9 PRP74330.1 - 2.6e-09 36.6 0.2 1.3e-08 34.3 0.0 2.0 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Lipase_3 PF01764.25 PRP74331.1 - 7.8e-27 93.9 0.0 1.3e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DHHC PF01529.20 PRP74331.1 - 1.6e-12 47.7 1.1 1.6e-12 47.7 1.1 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase Thioesterase PF00975.20 PRP74331.1 - 0.0089 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain SAP PF02037.27 PRP74332.1 - 1.1e-05 25.0 0.0 2.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain FYRC PF05965.14 PRP74333.1 - 0.15 12.3 0.0 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 F/Y rich C-terminus FSA_C PF10479.9 PRP74334.1 - 0.19 9.8 0.1 0.24 9.5 0.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pkinase_Tyr PF07714.17 PRP74336.1 - 1.1e-60 205.1 0.0 3e-60 203.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74336.1 - 2.1e-41 142.0 0.0 4.7e-41 140.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SBBP PF06739.11 PRP74336.1 - 3.7e-06 26.8 6.1 3.7e-06 26.8 6.1 6.3 6 1 0 6 6 6 3 Beta-propeller repeat Kdo PF06293.14 PRP74336.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PRP74337.1 - 1.1e-60 205.1 0.0 1.1e-60 205.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74337.1 - 1.6e-45 155.5 0.0 3.4e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP74337.1 - 0.093 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP74337.1 - 0.12 11.1 0.1 0.12 11.1 0.1 2.5 2 1 0 2 2 2 0 Fungal protein kinase Aminotran_1_2 PF00155.21 PRP74339.1 - 8.9e-43 146.8 0.0 1.2e-42 146.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SMG1 PF15785.5 PRP74339.1 - 0.077 11.4 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 DUF3301 PF11743.8 PRP74339.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) IncF PF17626.2 PRP74341.1 - 0.00036 20.8 5.7 1.6 9.1 0.4 4.0 4 0 0 4 4 4 2 Inclusion membrane protein F DUF4156 PF13698.6 PRP74341.1 - 0.0017 18.7 0.1 33 4.9 0.0 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF4156) CD34_antigen PF06365.12 PRP74341.1 - 0.42 10.2 2.4 16 5.0 0.1 2.5 3 0 0 3 3 3 0 CD34/Podocalyxin family CENP-F_leu_zip PF10473.9 PRP74344.1 - 0.021 14.8 2.1 0.032 14.2 0.5 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TetR_C_24 PF17932.1 PRP74344.1 - 0.033 14.5 0.2 0.068 13.4 0.2 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MIT PF04212.18 PRP74344.1 - 0.034 14.2 7.1 0.29 11.2 4.7 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain V-SNARE PF05008.15 PRP74344.1 - 0.21 12.0 4.7 0.1 13.0 1.2 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus MIP PF00230.20 PRP74345.1 - 7.2e-19 68.4 1.2 1e-18 67.9 1.2 1.3 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 PRP74346.1 - 8.4e-66 222.0 0.2 1.1e-65 221.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74346.1 - 1.6e-33 116.1 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP74346.1 - 1e-06 27.8 0.0 2.2e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP74346.1 - 4.9e-06 26.1 0.0 1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 PRP74346.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PRP74346.1 - 0.02 14.3 0.4 0.038 13.4 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP74346.1 - 0.032 13.8 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Methyltransf_13 PF08421.11 PRP74346.1 - 0.071 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative zinc binding domain LRR_8 PF13855.6 PRP74347.1 - 6.8e-08 32.2 6.0 0.00029 20.5 1.6 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PRP74347.1 - 3e-06 27.5 18.2 0.024 15.1 0.1 4.6 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP74347.1 - 1.5e-05 24.9 13.2 0.02 15.4 0.1 6.3 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP74347.1 - 7.1e-05 22.5 4.0 0.25 11.5 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 PRP74348.1 - 1.6e-09 37.4 18.3 2e-05 24.3 5.3 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PRP74348.1 - 1.1e-08 35.2 22.9 3.7e-05 24.0 1.5 4.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP74348.1 - 0.0025 18.1 18.0 2.9 8.8 0.7 5.4 4 1 1 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP74348.1 - 0.0034 17.3 10.2 0.015 15.3 0.1 4.5 5 0 0 5 5 5 1 Leucine Rich repeat Ank_2 PF12796.7 PRP74349.1 - 1.6e-50 169.6 0.1 1e-09 38.8 0.0 5.0 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP74349.1 - 3.7e-35 119.9 2.1 1.3e-06 28.8 0.0 9.4 1 1 10 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 PRP74349.1 - 3.6e-18 65.1 7.0 1 9.9 0.0 10.8 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 PRP74349.1 - 4.3e-17 62.0 0.4 3.4 8.1 0.0 9.2 5 3 5 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP74349.1 - 3.6e-11 42.3 0.1 8.1 7.4 0.0 10.0 11 0 0 11 11 11 1 Ankyrin repeat VapB_antitoxin PF09957.9 PRP74349.1 - 0.0064 16.4 0.3 6.6 6.7 0.0 4.2 4 0 0 4 4 4 1 Bacterial antitoxin of type II TA system, VapB YozD PF14162.6 PRP74350.1 - 0.0085 16.4 0.1 0.091 13.1 0.0 2.3 2 0 0 2 2 2 1 YozD-like protein PPR_2 PF13041.6 PRP74350.1 - 0.01 16.0 0.1 2.6 8.3 0.0 3.2 2 1 1 3 3 3 0 PPR repeat family ATP13 PF12921.7 PRP74350.1 - 0.014 15.2 0.0 0.19 11.6 0.0 2.5 2 1 0 2 2 2 0 Mitochondrial ATPase expression Phage_holin_6_1 PF09682.10 PRP74350.1 - 0.017 15.6 0.1 0.028 14.8 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Tantalus PF15386.6 PRP74350.1 - 0.18 11.9 1.1 3.4 7.8 0.1 2.2 1 1 1 2 2 2 0 Drosophila Tantalus-like Response_reg PF00072.24 PRP74352.1 - 3e-16 59.6 0.3 5.3e-16 58.8 0.2 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Uso1_p115_head PF04869.14 PRP74352.1 - 0.053 12.7 0.0 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region PCMT PF01135.19 PRP74354.1 - 1.6e-51 175.1 0.0 2.1e-50 171.4 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PRP74354.1 - 5.8e-09 35.9 0.0 6e-08 32.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PRP74354.1 - 1.6e-08 34.3 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PRP74354.1 - 3.8e-06 27.5 0.0 1.1e-05 26.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP74354.1 - 1.3e-05 25.7 0.1 0.00022 21.8 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 PRP74354.1 - 5.1e-05 23.3 0.0 9.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP74354.1 - 6.1e-05 22.5 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PRP74354.1 - 8.7e-05 22.4 0.0 0.00028 20.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 PRP74354.1 - 0.00042 20.1 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 PRP74354.1 - 0.00099 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 PRP74354.1 - 0.0037 17.4 0.0 0.012 15.7 0.0 1.8 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 PRP74354.1 - 0.005 15.8 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 PRP74354.1 - 0.017 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fibrillarin PF01269.17 PRP74354.1 - 0.076 12.1 0.0 0.18 10.9 0.0 1.5 1 1 1 2 2 2 0 Fibrillarin Methyltransf_18 PF12847.7 PRP74354.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 PRP74354.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa GAS PF13851.6 PRP74355.1 - 0.034 13.5 42.6 0.074 12.4 21.9 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 PRP74355.1 - 0.035 14.3 34.1 0.069 13.4 17.7 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 PRP74355.1 - 0.21 11.7 21.4 3.1 7.9 5.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 PRP74355.1 - 0.34 9.8 38.9 0.23 10.3 17.0 3.3 2 1 2 4 4 4 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 PRP74355.1 - 3.6 7.9 24.5 4.7 7.6 1.7 4.0 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 PRP74355.1 - 9 6.6 9.9 7.4 6.9 1.6 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Herpes_UL25 PF01499.16 PRP74355.1 - 9.9 4.6 20.3 0.051 12.1 5.7 2.6 1 1 2 3 3 3 0 Herpesvirus UL25 family Aquarius_N PF16399.5 PRP74360.1 - 0.0088 14.1 0.9 0.0095 14.0 0.2 1.4 2 0 0 2 2 2 1 Intron-binding protein aquarius N-terminus Bcr-Abl_Oligo PF09036.10 PRP74363.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF2135 PF09906.9 PRP74364.1 - 0.089 13.1 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) Hydantoinase_B PF02538.14 PRP74365.1 - 0.21 9.9 0.5 0.27 9.6 0.5 1.0 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase BST2 PF16716.5 PRP74365.1 - 0.31 11.7 10.5 0.23 12.0 0.7 3.0 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 rve PF00665.26 PRP74368.1 - 4.6e-13 49.4 0.0 1.1e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PRP74368.1 - 0.00039 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-RVT PF13966.6 PRP74371.1 - 0.026 15.2 0.4 0.026 15.2 0.4 2.5 1 1 0 2 2 2 0 zinc-binding in reverse transcriptase TetR_C_19 PF17924.1 PRP74371.1 - 0.041 14.5 1.3 0.1 13.2 0.2 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pkinase_Tyr PF07714.17 PRP74372.1 - 1.4e-14 54.0 0.1 4.9e-14 52.2 0.1 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74372.1 - 7.3e-12 45.2 0.1 1.3e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP74372.1 - 2.9e-06 27.7 4.7 2.9e-06 27.7 4.7 3.4 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif Chlam_PMP PF02415.17 PRP74372.1 - 0.00094 19.5 31.7 0.37 11.4 0.1 8.3 7 1 0 7 7 7 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Syndecan PF01034.20 PRP74372.1 - 0.0061 16.4 0.2 0.012 15.5 0.2 1.4 1 0 0 1 1 1 1 Syndecan domain Adeno_E3_CR2 PF02439.15 PRP74372.1 - 0.033 13.9 0.8 0.066 13.0 0.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FtsJ PF01728.19 PRP74373.1 - 3.5e-64 216.2 0.0 4.3e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF4460 PF14687.6 PRP74375.1 - 7.3e-10 38.9 1.1 7.3e-10 38.9 1.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 PRP74375.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DEAD PF00270.29 PRP74376.1 - 4.1e-27 95.1 0.1 9.5e-27 93.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rve PF00665.26 PRP74376.1 - 6.2e-15 55.4 0.2 1.4e-14 54.3 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain Helicase_C PF00271.31 PRP74376.1 - 4.8e-12 46.2 0.0 2.2e-11 44.1 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Integrase_H2C2 PF17921.1 PRP74376.1 - 2.5e-07 30.7 0.1 1e-06 28.8 0.1 2.1 1 0 0 1 1 1 1 Integrase zinc binding domain ResIII PF04851.15 PRP74376.1 - 3.5e-05 23.9 0.1 0.00033 20.7 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit rve_3 PF13683.6 PRP74376.1 - 0.00028 20.6 1.1 0.0018 18.0 0.1 2.5 2 0 0 2 2 2 1 Integrase core domain SecA_DEAD PF07517.14 PRP74376.1 - 0.11 11.8 0.0 0.47 9.7 0.0 2.0 3 0 0 3 3 3 0 SecA DEAD-like domain DMRT-like PF15791.5 PRP74376.1 - 6.7 7.2 6.7 1.3 9.5 1.7 2.3 2 0 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 Stk19 PF10494.9 PRP74378.1 - 0.18 11.5 1.0 0.23 11.1 1.0 1.1 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 MORN PF02493.20 PRP74379.1 - 7.6e-53 173.4 85.5 4.7e-10 38.8 2.7 10.3 10 0 0 10 10 10 10 MORN repeat F-box-like PF12937.7 PRP74379.1 - 8.4e-12 44.8 0.6 1.9e-11 43.7 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP74379.1 - 4.3e-09 36.0 0.7 9.1e-09 35.0 0.7 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 PRP74379.1 - 0.0015 18.8 0.1 0.0032 17.7 0.1 1.5 1 0 0 1 1 1 1 PRANC domain Aurora-A_bind PF09041.10 PRP74380.1 - 0.00043 20.3 1.3 0.00092 19.2 0.1 2.1 2 0 0 2 2 2 1 Aurora-A binding TPX2_importin PF12214.8 PRP74380.1 - 0.019 15.2 0.2 0.019 15.2 0.2 4.4 3 2 2 5 5 5 0 Cell cycle regulated microtubule associated protein Keratin_B2 PF01500.17 PRP74380.1 - 0.54 10.2 4.5 1.3 9.0 4.5 1.7 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Vezatin PF12632.7 PRP74381.1 - 2.3e-12 46.9 0.2 6.6e-12 45.4 0.2 1.7 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes SelP_N PF04592.14 PRP74382.1 - 0.082 12.3 15.7 0.12 11.8 15.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BHD_3 PF10405.9 PRP74383.1 - 8.8e-27 93.3 0.0 2e-26 92.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 PRP74383.1 - 1.6e-14 53.8 0.1 1.6e-14 53.8 0.1 3.0 2 1 1 3 3 3 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 PRP74383.1 - 8.4e-14 52.3 1.7 8.4e-14 52.3 1.7 5.9 5 1 0 5 5 5 2 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 PRP74383.1 - 5.9e-13 48.4 0.1 1.5e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 PRP74383.1 - 1.4e-05 25.5 0.0 3.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad52_Rad22 PF04098.15 PRP74383.1 - 0.06 13.3 2.7 0.051 13.5 0.6 1.9 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein 2OG-FeII_Oxy_3 PF13640.6 PRP74384.1 - 2.8e-07 31.3 0.1 4.7e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA-synt_2b PF00587.25 PRP74385.1 - 2e-26 93.1 0.1 4.5e-26 91.9 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PRP74385.1 - 4.4e-07 30.1 7.6 9.6e-05 22.6 7.6 2.4 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain She9_MDM33 PF05546.11 PRP74385.1 - 0.45 10.3 4.5 0.82 9.4 4.5 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family Dymeclin PF09742.9 PRP74386.1 - 4.4e-92 309.5 17.0 4.9e-92 309.4 17.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 PRP74386.1 - 1.2e-12 46.9 20.0 4.6e-08 31.7 7.4 3.3 2 1 0 3 3 3 3 High-temperature-induced dauer-formation protein HD PF01966.22 PRP74387.1 - 1.4e-13 51.1 0.5 3.6e-13 49.8 0.5 1.7 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 PRP74387.1 - 0.00047 20.0 0.5 0.0019 18.0 0.4 1.8 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MatB PF16449.5 PRP74387.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Fimbrillin MatB HDOD PF08668.12 PRP74387.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 HDOD domain DNA_ligase_A_M PF01068.21 PRP74389.1 - 8.9e-50 169.2 0.1 1.8e-49 168.2 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PRP74389.1 - 1.5e-34 119.8 0.3 3.8e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus G8 PF10162.9 PRP74389.1 - 1.2e-21 77.1 0.5 3.3e-21 75.6 0.1 2.0 2 0 0 2 2 2 1 G8 domain DNA_ligase_A_C PF04679.15 PRP74389.1 - 2.3e-18 66.6 0.0 8.8e-18 64.7 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 PRP74389.1 - 9e-11 42.0 2.1 1.7e-05 25.1 0.1 3.7 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RNA_ligase PF09414.10 PRP74389.1 - 1.6e-08 35.0 0.1 3.9e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 RNA ligase DNA_ligase_IV PF11411.8 PRP74389.1 - 2.3e-08 34.0 0.3 4.8e-08 33.0 0.3 1.6 1 0 0 1 1 1 1 DNA ligase IV BRCT_2 PF16589.5 PRP74389.1 - 3.7e-08 33.7 0.1 1.2e-05 25.6 0.0 3.7 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain mRNA_cap_enzyme PF01331.19 PRP74389.1 - 0.00016 21.5 0.4 0.036 13.9 0.1 3.2 3 0 0 3 3 3 1 mRNA capping enzyme, catalytic domain SNARE PF05739.19 PRP74390.1 - 2.8e-13 49.6 0.0 6.7e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 PRP74390.1 - 4.1e-09 36.7 4.7 5.6e-09 36.3 0.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 PRP74390.1 - 0.00028 20.6 4.5 0.00086 19.0 0.2 2.2 2 0 0 2 2 2 1 Syntaxin PLDc_N PF13396.6 PRP74390.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal TMF_TATA_bd PF12325.8 PRP74390.1 - 0.037 14.2 1.2 0.037 14.2 1.2 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.11 PRP74390.1 - 0.11 10.4 0.7 0.18 9.7 0.2 1.5 1 1 1 2 2 2 0 Prominin UPF0242 PF06785.11 PRP74390.1 - 0.2 11.8 5.3 1.7 8.7 0.7 2.2 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 PRP74390.1 - 0.2 11.9 1.2 16 5.9 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 PRP74390.1 - 0.46 10.5 2.9 1.2 9.2 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 PRP74390.1 - 2.3 8.9 8.9 20 5.9 0.4 3.4 3 1 1 4 4 4 0 SlyX BTK PF00779.19 PRP74392.1 - 0.0039 17.0 1.7 0.0039 17.0 1.7 2.1 2 0 0 2 2 2 1 BTK motif CHORD PF04968.12 PRP74392.1 - 0.054 14.2 1.0 0.054 14.2 1.0 2.9 3 0 0 3 3 3 0 CHORD zinc_ribbon_4 PF13717.6 PRP74392.1 - 0.074 13.0 0.8 4.3 7.3 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 PRP74392.1 - 0.26 11.1 2.2 0.7 9.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase_Tyr PF07714.17 PRP74393.1 - 8.2e-72 241.6 0.0 1.2e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74393.1 - 1.6e-50 171.9 0.0 2.5e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP74393.1 - 7e-47 157.0 111.3 2.5e-08 33.6 2.9 15.4 8 4 9 18 18 18 14 Leucine rich repeat LRR_4 PF12799.7 PRP74393.1 - 6.4e-45 150.4 109.9 1.6e-05 25.2 0.3 19.0 17 3 3 20 20 19 14 Leucine Rich repeats (2 copies) MBOAT PF03062.19 PRP74393.1 - 1.4e-24 87.2 16.2 1.4e-24 87.1 14.5 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ank_2 PF12796.7 PRP74393.1 - 1.5e-15 57.6 1.6 3.7e-07 30.6 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP74393.1 - 1.5e-10 41.4 5.3 0.021 15.4 0.2 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP74393.1 - 3.5e-06 26.9 0.8 3 8.7 0.0 5.7 5 0 0 5 5 4 1 Ankyrin repeat Ank_5 PF13857.6 PRP74393.1 - 0.00022 21.5 1.2 0.12 12.7 0.1 4.5 3 1 2 5 5 5 1 Ankyrin repeats (many copies) LRR_1 PF00560.33 PRP74393.1 - 0.00071 19.8 105.5 2.3 9.1 0.0 26.1 28 2 0 28 28 26 5 Leucine Rich Repeat Ank PF00023.30 PRP74393.1 - 0.011 16.1 1.3 12 6.5 0.1 4.8 3 1 1 4 4 4 0 Ankyrin repeat Stevor PF17410.2 PRP74393.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LRRNT_2 PF08263.12 PRP74393.1 - 0.22 11.9 0.8 0.67 10.3 0.8 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain SPX PF03105.19 PRP74393.1 - 2.1 8.2 10.3 4 7.2 10.3 1.4 1 0 0 1 1 1 0 SPX domain DUF1180 PF06679.12 PRP74393.1 - 2.5 8.5 5.6 0.19 12.1 0.2 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1180) SAP PF02037.27 PRP74394.1 - 2.3e-08 33.6 0.0 4.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 PRP74394.1 - 0.0089 15.7 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 HeH/LEM domain Rho_N PF07498.12 PRP74394.1 - 0.098 12.6 0.0 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Peptidase_M20 PF01546.28 PRP74395.1 - 1.4e-29 103.3 0.0 2.7e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 PRP74395.1 - 9.2e-22 76.9 16.4 0.00026 21.7 0.2 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat GATase_4 PF13230.6 PRP74395.1 - 6.6e-19 67.9 0.0 1.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 PRP74395.1 - 8.5e-16 58.4 0.0 1.9e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Nup160 PF11715.8 PRP74395.1 - 0.004 15.9 6.2 0.016 13.9 0.4 3.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 PRP74395.1 - 0.024 15.1 0.1 44 4.7 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain Peptidase_M28 PF04389.17 PRP74395.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 PP2C PF00481.21 PRP74396.1 - 7.5e-64 215.8 0.0 1e-63 215.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PRP74396.1 - 0.00022 20.9 0.1 0.00095 18.9 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C IQ PF00612.27 PRP74397.1 - 5e-07 29.0 9.7 0.0056 16.4 0.1 4.6 4 0 0 4 4 4 3 IQ calmodulin-binding motif Ras PF00071.22 PRP74398.1 - 8.8e-58 194.5 1.6 1e-57 194.2 1.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP74398.1 - 4.5e-34 117.3 0.2 7.3e-34 116.6 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP74398.1 - 1.9e-15 56.7 0.2 2.6e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP74398.1 - 6e-06 25.8 0.1 7.6e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP74398.1 - 6.6e-06 26.2 0.3 1.3e-05 25.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP74398.1 - 0.00022 20.8 0.9 0.00046 19.8 0.9 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PRP74398.1 - 0.00031 20.2 0.0 0.00047 19.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PRP74398.1 - 0.00084 19.3 1.2 0.041 13.8 0.1 2.1 1 1 1 2 2 2 1 RsgA GTPase TniB PF05621.11 PRP74398.1 - 0.0016 17.9 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein AAA_24 PF13479.6 PRP74398.1 - 0.0069 16.1 0.2 0.015 15.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 PRP74398.1 - 0.011 15.2 0.6 0.028 13.9 0.6 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 PRP74398.1 - 0.03 14.7 0.0 0.042 14.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 PRP74398.1 - 0.049 13.7 0.1 0.13 12.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PRP74398.1 - 0.072 12.6 0.2 0.23 10.9 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ParcG PF10274.9 PRP74400.1 - 1.6e-40 139.2 0.0 2.3e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Parkin co-regulated protein T3SSipB PF16535.5 PRP74401.1 - 0.00012 22.5 5.3 0.00012 22.5 5.3 3.8 2 1 0 3 3 3 2 Type III cell invasion protein SipB FPP PF05911.11 PRP74401.1 - 0.0024 16.2 59.6 0.15 10.2 18.9 3.1 1 1 2 3 3 3 3 Filament-like plant protein, long coiled-coil EzrA PF06160.12 PRP74401.1 - 0.074 11.2 45.0 0.12 10.5 9.8 3.3 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 PRP74401.1 - 0.57 10.2 67.0 0.046 13.7 15.8 4.9 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 PRP74401.1 - 1.9 8.4 66.5 0.086 12.9 12.0 4.2 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion UPF0242 PF06785.11 PRP74401.1 - 3.5 7.7 68.0 1.6 8.8 19.2 4.3 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus RhoGEF PF00621.20 PRP74403.1 - 7.9e-33 114.2 0.0 1.3e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Glyoxalase_3 PF13468.6 PRP74404.1 - 5.8e-17 62.4 0.0 7.2e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain B2-adapt-app_C PF09066.10 PRP74404.1 - 0.098 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain BTB PF00651.31 PRP74406.1 - 1.3e-16 60.8 0.0 3.1e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PRP74406.1 - 2e-09 37.5 0.1 7.1e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 BTB And C-terminal Kelch BTK PF00779.19 PRP74406.1 - 0.014 15.2 5.6 0.035 13.9 5.6 1.7 1 0 0 1 1 1 0 BTK motif LRR_8 PF13855.6 PRP74407.1 - 1.6e-07 31.0 39.6 0.0001 22.0 3.8 8.3 4 3 5 9 9 9 6 Leucine rich repeat LRR_4 PF12799.7 PRP74407.1 - 1.4e-05 25.3 42.9 0.00026 21.3 0.3 8.6 7 3 2 9 9 9 5 Leucine Rich repeats (2 copies) Podoplanin PF05808.11 PRP74407.1 - 0.00018 21.6 2.8 0.00033 20.8 2.8 1.3 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.20 PRP74407.1 - 0.015 15.2 4.4 0.034 14.0 4.4 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4690 PF15756.5 PRP74407.1 - 0.039 14.5 0.0 0.098 13.3 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage PI_PP_I PF18363.1 PRP74407.1 - 0.044 14.0 0.4 16 5.7 0.1 2.7 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Rax2 PF12768.7 PRP74407.1 - 0.082 12.3 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Cortical protein marker for cell polarity NIF3 PF01784.18 PRP74408.1 - 3.3e-72 243.1 0.0 4.5e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) CutA1 PF03091.15 PRP74408.1 - 0.001 18.9 0.1 0.0066 16.3 0.0 2.2 2 0 0 2 2 2 1 CutA1 divalent ion tolerance protein Nsp1_C PF05064.13 PRP74408.1 - 0.41 10.5 1.9 0.76 9.6 0.3 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region Insulin_TMD PF17870.1 PRP74409.1 - 0.077 13.1 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment RRM_1 PF00076.22 PRP74411.1 - 1.1e-13 50.8 0.1 2e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 PRP74411.1 - 0.0075 16.9 5.0 0.0075 16.9 5.0 3.3 3 0 0 3 3 3 1 Glycine rich protein family EF-hand_6 PF13405.6 PRP74412.1 - 0.023 14.6 0.6 10 6.4 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 PRP74412.1 - 0.045 13.3 1.9 4.5 7.0 0.1 2.4 2 0 0 2 2 2 0 EF hand Ldl_recept_a PF00057.18 PRP74414.1 - 1.5 9.1 6.8 0.53 10.6 0.9 2.3 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A FtsX PF02687.21 PRP74415.1 - 1.6e-13 50.9 22.3 3.1e-11 43.6 6.9 6.6 6 1 0 6 6 6 3 FtsX-like permease family MacB_PCD PF12704.7 PRP74415.1 - 0.013 15.8 3.3 2.6 8.4 1.1 3.1 2 0 0 2 2 2 0 MacB-like periplasmic core domain FMO-like PF00743.19 PRP74416.1 - 8.1e-18 64.1 0.1 3.1e-17 62.2 0.1 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PRP74416.1 - 2.2e-13 50.2 3.2 8.3e-11 41.7 1.7 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PRP74416.1 - 2.4e-13 50.0 0.1 5.9e-12 45.4 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PRP74416.1 - 6.5e-12 45.2 0.1 2.1e-09 37.0 0.0 2.5 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PRP74416.1 - 1.5e-09 37.9 1.6 1.1e-08 35.2 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 PRP74416.1 - 7.1e-08 32.0 1.1 0.00092 18.6 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 PRP74416.1 - 1.4e-06 28.8 2.6 0.0068 16.9 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 PRP74416.1 - 3.4e-05 23.3 0.1 0.0059 15.9 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 PRP74416.1 - 4.1e-05 23.3 0.0 4.1e-05 23.3 0.0 1.9 3 0 0 3 3 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PRP74416.1 - 5.8e-05 22.6 0.4 5.8e-05 22.6 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PRP74416.1 - 0.00026 21.0 3.7 0.0008 19.4 0.2 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 PRP74416.1 - 0.0018 18.3 0.5 1.2 9.2 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 PRP74416.1 - 0.0019 17.4 0.9 0.0019 17.4 0.9 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 PRP74416.1 - 0.0022 16.8 4.6 0.0084 14.9 1.5 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.6 PRP74416.1 - 0.0055 17.1 0.2 0.76 10.3 0.1 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 PRP74416.1 - 0.018 14.1 7.8 0.056 12.5 1.8 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 PRP74416.1 - 0.062 13.2 0.4 0.15 11.9 0.4 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 PRP74416.1 - 0.069 11.9 0.6 0.1 11.4 0.6 1.2 1 0 0 1 1 1 0 MCRA family 2-Hacid_dh_C PF02826.19 PRP74416.1 - 0.095 12.0 0.3 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 PRP74416.1 - 0.24 10.6 2.3 0.24 10.6 0.4 1.8 2 0 0 2 2 2 0 Thi4 family Ribophorin_II PF05817.14 PRP74417.1 - 5.6e-58 197.0 0.3 6.7e-58 196.7 0.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II SPC22 PF04573.12 PRP74417.1 - 0.26 10.8 2.5 0.16 11.5 0.4 1.7 2 0 0 2 2 2 0 Signal peptidase subunit Wzy_C PF04932.15 PRP74417.1 - 1.6 8.3 5.7 2.8 7.6 2.8 2.2 2 1 0 2 2 2 0 O-Antigen ligase Spt4 PF06093.13 PRP74418.1 - 2.2e-29 101.3 0.3 3.1e-29 100.9 0.3 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger DUF2250 PF10007.9 PRP74419.1 - 0.22 11.6 3.4 0.41 10.8 3.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) UQ_con PF00179.26 PRP74420.1 - 2.8e-20 72.4 0.0 5e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FlxA PF14282.6 PRP74420.1 - 0.017 15.1 0.3 0.047 13.7 0.3 1.7 1 0 0 1 1 1 0 FlxA-like protein DUF2756 PF10956.8 PRP74420.1 - 0.017 15.6 0.2 0.032 14.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Exonuc_VIII PF06630.11 PRP74420.1 - 0.076 12.9 1.6 1.7 8.4 0.2 2.1 1 1 1 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII PRIMA1 PF16101.5 PRP74420.1 - 0.091 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 F5_F8_type_C PF00754.25 PRP74421.1 - 2.1e-05 24.6 0.0 2.4e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain SARS_X4 PF08779.10 PRP74421.1 - 0.043 14.0 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 SARS coronavirus X4 like Glyco_transf_90 PF05686.12 PRP74422.1 - 3.7e-11 42.6 0.8 3.1e-07 29.6 1.2 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF5039 PF16442.5 PRP74422.1 - 2.8 7.5 5.0 1.2 8.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5039) GFO_IDH_MocA PF01408.22 PRP74423.1 - 9.6e-20 71.6 0.1 2.4e-19 70.3 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RVT_1 PF00078.27 PRP74423.1 - 1.1e-13 51.3 0.0 2.6e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GFO_IDH_MocA_C PF02894.17 PRP74423.1 - 0.0013 18.7 0.0 0.0048 16.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain zf-RVT PF13966.6 PRP74423.1 - 0.0091 16.7 0.1 0.037 14.7 0.1 2.1 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF2688 PF10892.8 PRP74423.1 - 0.027 13.9 0.3 0.07 12.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Glyco_hydro_31 PF01055.26 PRP74424.1 - 2e-153 511.8 2.0 2.5e-153 511.4 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 PRP74424.1 - 8.9e-32 109.7 0.1 2.1e-31 108.5 0.1 1.7 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 PRP74424.1 - 8.5e-14 51.6 0.1 2.7e-13 50.0 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 PRP74424.1 - 0.12 12.7 3.0 0.17 12.2 0.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5110) HA PF03457.14 PRP74425.1 - 5.5e-15 55.5 1.2 8.6e-15 54.8 1.2 1.3 1 0 0 1 1 1 1 Helicase associated domain THP2 PF09432.10 PRP74425.1 - 0.022 14.8 0.2 0.039 14.0 0.2 1.3 1 0 0 1 1 1 0 Tho complex subunit THP2 DUF2189 PF09955.9 PRP74425.1 - 0.097 12.9 1.9 0.22 11.8 1.4 1.8 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF4106 PF13388.6 PRP74425.1 - 0.16 11.2 2.7 0.22 10.7 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MORN PF02493.20 PRP74427.1 - 5.7e-41 136.0 70.4 8e-05 22.3 0.7 14.6 14 0 0 14 14 14 13 MORN repeat RhoGEF PF00621.20 PRP74427.1 - 6.5e-40 137.3 0.3 1.2e-39 136.5 0.3 1.4 1 0 0 1 1 1 1 RhoGEF domain WH1 PF00568.23 PRP74427.1 - 1.5e-05 24.9 0.1 3.5e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 WH1 domain Synaptobrevin PF00957.21 PRP74427.1 - 0.0071 16.1 0.8 0.66 9.8 0.0 2.4 2 0 0 2 2 2 1 Synaptobrevin Ribosomal_L9_C PF03948.14 PRP74427.1 - 0.017 15.5 0.1 0.036 14.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain Sec1 PF00995.23 PRP74428.1 - 1.5e-117 394.3 2.5 1.5e-117 394.3 2.5 1.6 2 0 0 2 2 2 1 Sec1 family PRP9_N PF16958.5 PRP74428.1 - 0.051 13.6 2.1 1.9 8.5 0.1 2.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus Pkinase PF00069.25 PRP74429.1 - 2.5e-48 164.8 0.0 3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74429.1 - 1.7e-26 93.1 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP74429.1 - 6.9e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP74429.1 - 9.9e-06 24.7 0.0 1.7e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP74429.1 - 4.3e-05 23.0 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP74429.1 - 4.8e-05 23.4 0.1 0.00012 22.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP74429.1 - 0.0024 16.7 0.0 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 PRP74429.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 PRP74429.1 - 0.14 11.2 0.1 0.31 10.0 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 GSH_synth_ATP PF03917.17 PRP74430.1 - 7.2e-121 403.5 0.0 8.2e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 PRP74430.1 - 1.7e-35 121.6 0.0 4.5e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic glutathione synthase LEA_4 PF02987.16 PRP74432.1 - 0.34 11.0 11.9 1.1 9.4 0.9 4.0 3 0 0 3 3 3 0 Late embryogenesis abundant protein Aldedh PF00171.22 PRP74433.1 - 8.1e-82 275.2 0.0 1e-81 274.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fz PF01392.22 PRP74434.1 - 9.3e-05 23.0 11.2 0.00021 21.9 10.8 1.8 1 1 0 1 1 1 1 Fz domain Pox_A21 PF05323.12 PRP74434.1 - 0.082 13.5 0.1 0.082 13.5 0.1 1.9 2 0 0 2 2 2 0 Poxvirus A21 Protein FF PF01846.19 PRP74435.1 - 3.9e-35 119.8 21.0 7.6e-09 35.6 0.1 6.1 6 0 0 6 6 6 5 FF domain WW PF00397.26 PRP74435.1 - 3.1e-16 59.2 18.5 4.4e-08 33.1 4.0 2.8 2 0 0 2 2 2 2 WW domain PRD PF00874.20 PRP74435.1 - 0.15 12.4 2.0 3.3 8.1 0.1 3.3 3 0 0 3 3 3 0 PRD domain Glyco_hyd_101C PF17451.2 PRP74435.1 - 6.2 7.1 11.8 4.1 7.7 1.4 3.2 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain Cofac_haem_bdg PF04187.13 PRP74437.1 - 2e-23 83.5 3.4 9.6e-22 78.0 0.0 3.3 1 1 1 3 3 3 1 Haem-binding uptake, Tiki superfamily, ChaN CDC27 PF09507.10 PRP74437.1 - 0.011 15.2 2.3 0.018 14.5 2.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FapA PF03961.13 PRP74437.1 - 0.032 12.8 1.4 0.04 12.5 0.6 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Histone_HNS PF00816.21 PRP74437.1 - 6.1 7.7 7.3 26 5.7 0.0 2.7 2 1 0 2 2 2 0 H-NS histone family BRO1 PF03097.18 PRP74439.1 - 3.8e-112 374.9 5.8 6.4e-112 374.2 5.8 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 PRP74439.1 - 1.2e-68 231.7 10.2 1.2e-68 231.7 10.2 3.5 4 0 0 4 4 4 1 ALIX V-shaped domain binding to HIV TaqI_C PF12950.7 PRP74439.1 - 0.071 13.2 0.1 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 TaqI-like C-terminal specificity domain SLATT_5 PF18160.1 PRP74439.1 - 0.32 10.3 4.0 0.35 10.2 0.8 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Hemerythrin PF01814.23 PRP74439.1 - 1.3 9.6 12.2 2.2 8.9 1.1 4.7 5 0 0 5 5 5 0 Hemerythrin HHE cation binding domain DASH_Duo1 PF08651.10 PRP74439.1 - 2.1 8.2 6.1 0.36 10.6 0.1 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF148 PF02520.17 PRP74439.1 - 3.8 7.7 6.2 9.4 6.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF148 UPF0242 PF06785.11 PRP74441.1 - 0.017 15.3 0.1 0.026 14.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4834 PF16118.5 PRP74441.1 - 0.14 13.2 2.3 0.15 13.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3517 PF12030.8 PRP74442.1 - 0.034 13.1 1.0 0.045 12.7 0.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3517) XRCC1_N PF01834.16 PRP74443.1 - 2e-21 76.6 0.9 4.1e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 XRCC1 N terminal domain BRCT PF00533.26 PRP74443.1 - 0.00023 21.5 0.0 0.00085 19.7 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP74443.1 - 0.00033 21.0 0.0 0.001 19.4 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 PRP74443.1 - 0.0016 18.7 0.0 0.0047 17.2 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 PRP74443.1 - 0.0016 18.3 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain F5_F8_type_C PF00754.25 PRP74443.1 - 0.0036 17.4 0.0 0.0088 16.2 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain Pkinase PF00069.25 PRP74444.1 - 1.2e-61 208.4 0.2 1.5e-61 208.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74444.1 - 2.3e-27 95.9 0.0 3.6e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP74444.1 - 8.3e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP74444.1 - 2e-05 24.6 0.0 0.0045 17.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP74444.1 - 5.3e-05 22.7 0.1 8.8e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP74444.1 - 0.002 17.1 1.0 0.0047 15.9 1.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 PRP74444.1 - 0.0063 16.1 0.3 0.021 14.4 0.2 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PRP74444.1 - 0.013 14.3 0.3 0.037 12.8 0.3 1.7 1 1 0 1 1 1 0 Fungal protein kinase GPR15L PF15854.5 PRP74444.1 - 0.075 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Mre11_DNA_bind PF04152.14 PRP74445.1 - 1.2e-44 152.6 0.1 1.2e-44 152.6 0.1 2.3 2 1 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 PRP74445.1 - 8.2e-14 52.6 2.8 1.8e-13 51.4 2.8 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PRP74445.1 - 3.1e-06 27.5 0.0 0.0001 22.5 0.0 3.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain RAMP4 PF06624.12 PRP74446.1 - 0.068 13.2 0.9 0.17 11.9 0.9 1.6 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Cyclin PF08613.11 PRP74447.1 - 0.045 14.1 0.0 0.049 14.0 0.0 1.1 1 0 0 1 1 1 0 Cyclin Bap31 PF05529.12 PRP74454.1 - 8.3e-12 45.1 4.8 2e-11 43.9 4.8 1.6 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF1980 PF09323.10 PRP74454.1 - 0.0095 15.9 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) Bystin PF05291.11 PRP74455.1 - 4.6e-120 400.3 0.8 7.7e-120 399.6 0.8 1.3 1 0 0 1 1 1 1 Bystin DUF4050 PF13259.6 PRP74455.1 - 1.7 9.0 7.5 3 8.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Ldt_C PF17969.1 PRP74455.1 - 4.7 8.0 6.9 0.91 10.3 1.3 2.5 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain DUF4637 PF15470.6 PRP74457.1 - 0.045 13.5 0.5 0.086 12.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ras PF00071.22 PRP74459.1 - 1.4e-46 158.1 0.0 2.3e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Ras family mRNA_cap_enzyme PF01331.19 PRP74459.1 - 1.5e-31 109.8 1.0 2.7e-31 108.9 1.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Roc PF08477.13 PRP74459.1 - 7.1e-22 77.9 0.0 1.7e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase mRNA_triPase PF02940.15 PRP74459.1 - 3.5e-09 36.7 4.2 7.5e-08 32.4 2.6 2.8 1 1 1 2 2 2 1 mRNA capping enzyme, beta chain mRNA_cap_C PF03919.15 PRP74459.1 - 5e-09 36.8 0.3 1.8e-08 35.0 0.3 1.9 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain Arf PF00025.21 PRP74459.1 - 2.4e-05 23.9 0.0 5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP74459.1 - 0.0005 20.1 0.0 0.0023 18.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase DNA_ligase_A_M PF01068.21 PRP74459.1 - 0.00084 19.0 0.2 0.14 11.8 0.1 2.9 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Pox_ATPase-GT PF10640.9 PRP74459.1 - 0.0034 16.3 0.0 0.0067 15.3 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase RFamide_26RFa PF11109.8 PRP74459.1 - 0.037 14.5 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 SNF2_N PF00176.23 PRP74460.1 - 6.1e-58 196.2 0.1 9.4e-58 195.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP74460.1 - 4.4e-05 23.8 0.0 0.00034 20.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HypA PF01155.19 PRP74460.1 - 0.037 14.0 3.1 0.26 11.3 0.9 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 PRP74460.1 - 0.13 12.2 1.0 0.53 10.2 1.0 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Cript PF10235.9 PRP74460.1 - 0.27 11.8 1.9 0.62 10.7 1.9 1.5 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Cytochrom_c3_2 PF14537.6 PRP74460.1 - 2.1 8.9 7.2 5.7 7.5 7.2 1.8 1 0 0 1 1 1 0 Cytochrome c3 Bmt2 PF11968.8 PRP74461.1 - 1e-47 162.9 0.0 8.2e-32 110.8 0.1 2.4 2 0 0 2 2 2 2 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Cu2_monooxygen PF01082.20 PRP74461.1 - 0.044 14.0 0.4 10 6.4 0.5 2.4 2 0 0 2 2 2 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Methyltransf_12 PF08242.12 PRP74461.1 - 0.1 13.3 0.2 0.35 11.6 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain ALMT PF11744.8 PRP74461.1 - 1.8 7.3 4.0 2.8 6.6 4.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter U-box PF04564.15 PRP74462.1 - 9.5e-17 60.9 0.1 3.9e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 U-box domain Peptidase_M14 PF00246.24 PRP74462.1 - 8.5e-16 58.6 0.0 5.7e-15 55.9 0.0 2.4 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 PRP74462.1 - 1.9e-12 47.5 0.2 3.9e-12 46.5 0.2 1.6 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain zf-Nse PF11789.8 PRP74462.1 - 5.1e-05 23.0 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PYRIN PF02758.16 PRP74462.1 - 0.0095 16.1 0.1 4.1 7.6 0.0 2.9 2 0 0 2 2 2 1 PAAD/DAPIN/Pyrin domain zf-RING_UBOX PF13445.6 PRP74462.1 - 0.016 15.2 0.0 0.052 13.6 0.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-NOSIP PF15906.5 PRP74462.1 - 0.017 15.2 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Atg14 PF10186.9 PRP74462.1 - 0.98 8.4 10.3 2.3 7.2 10.3 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TM2 PF05154.16 PRP74463.1 - 3.8e-12 46.4 9.1 6.8e-12 45.5 9.1 1.4 1 0 0 1 1 1 1 TM2 domain zf-MYND PF01753.18 PRP74463.1 - 9.8e-07 28.8 8.3 2.7e-06 27.4 8.3 1.7 1 0 0 1 1 1 1 MYND finger Choline_transpo PF04515.12 PRP74464.1 - 4.6e-87 292.3 35.3 4.6e-87 292.3 35.3 2.4 3 0 0 3 3 3 2 Plasma-membrane choline transporter TRAP_beta PF05753.14 PRP74464.1 - 0.15 11.5 0.1 0.5 9.7 0.1 2.0 1 1 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Hol_Tox PF16935.5 PRP74464.1 - 0.36 10.9 2.8 0.43 10.7 0.4 2.4 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) DUF1075 PF06388.11 PRP74464.1 - 1.1 9.3 2.8 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1075) DUF3664 PF12406.8 PRP74464.1 - 4.9 7.8 11.5 8.9 7.0 11.5 1.4 1 0 0 1 1 1 0 Surface protein Ank_2 PF12796.7 PRP74465.1 - 5.3e-07 30.1 0.0 4.9e-05 23.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP74465.1 - 0.015 15.8 0.0 1.3 9.9 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 PRP74465.1 - 0.015 15.8 0.1 17 6.2 0.0 3.4 2 1 2 4 4 4 0 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 PRP74467.1 - 6.2e-35 116.2 20.1 2.7e-09 35.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PRP74467.1 - 4e-30 104.1 11.6 6.1e-16 58.6 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP74467.1 - 2.1e-27 92.7 12.1 1.4e-09 37.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PRP74467.1 - 5.4e-27 93.4 14.8 3e-13 49.4 1.0 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PRP74467.1 - 1.4e-17 62.2 19.5 4.9e-06 25.8 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PRP74467.1 - 1.7e-14 53.8 0.3 1.1e-06 28.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PRP74467.1 - 1.3e-06 28.2 8.1 0.11 12.5 0.8 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PRP74467.1 - 2.3e-05 24.7 0.7 0.13 12.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 PRP74467.1 - 0.00029 20.6 1.6 0.19 11.5 0.1 2.1 1 1 1 2 2 2 2 SurA N-terminal domain Dockerin_1 PF00404.18 PRP74467.1 - 0.00078 19.6 0.6 0.56 10.5 0.1 2.4 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_14 PF17959.1 PRP74467.1 - 0.001 19.3 1.6 0.53 10.7 0.2 2.4 1 1 1 2 2 2 2 EF-hand domain SurA_N_2 PF13623.6 PRP74467.1 - 0.01 15.7 2.2 0.96 9.3 0.4 2.6 1 1 1 2 2 2 0 SurA N-terminal domain PMBR PF09373.10 PRP74467.1 - 0.012 15.7 0.7 47 4.4 0.0 4.8 5 0 0 5 5 5 0 Pseudomurein-binding repeat DUF3349 PF11829.8 PRP74467.1 - 0.023 15.5 1.8 9.2 7.1 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) TerB PF05099.13 PRP74467.1 - 0.026 14.5 2.7 0.21 11.5 0.0 2.6 1 1 2 3 3 3 0 Tellurite resistance protein TerB DUF853 PF05872.12 PRP74467.1 - 0.03 12.9 0.4 1.5 7.3 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_11 PF08976.11 PRP74467.1 - 0.036 14.9 0.3 8.2 7.4 0.1 2.2 1 1 1 2 2 2 0 EF-hand domain DUF4601 PF15373.6 PRP74467.1 - 0.046 12.7 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) Phg_2220_C PF09524.10 PRP74467.1 - 0.081 13.0 0.5 1.9 8.6 0.1 2.2 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) UPF0154 PF03672.13 PRP74467.1 - 0.097 12.7 0.0 6.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 PRP74467.1 - 0.1 12.5 1.2 7.8 6.4 0.0 3.3 1 1 3 4 4 4 0 Caleosin related protein FlgD PF03963.14 PRP74467.1 - 0.11 12.8 1.2 0.32 11.3 0.8 2.1 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region SUB1_ProdP9 PF18213.1 PRP74467.1 - 0.11 12.3 1.9 0.13 12.1 0.4 1.8 1 1 0 2 2 2 0 SUB1 protease Prodomain ProdP9 LETM1 PF07766.13 PRP74467.1 - 0.16 11.3 1.5 0.4 10.0 1.3 1.9 1 1 0 1 1 1 0 LETM1-like protein DUF1542 PF07564.11 PRP74467.1 - 0.2 11.8 4.4 7.4 6.8 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) DUF2757 PF10955.8 PRP74467.1 - 0.26 11.5 2.2 4.3 7.7 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2757) Gp-FAR-1 PF05823.12 PRP74467.1 - 0.33 11.3 5.2 0.64 10.4 0.3 2.8 2 1 0 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MgtE_N PF03448.17 PRP74467.1 - 0.66 10.6 4.7 0.37 11.4 1.1 2.3 3 0 0 3 3 2 0 MgtE intracellular N domain SRI PF08236.11 PRP74467.1 - 0.86 9.8 3.8 1.2 9.3 0.1 2.7 2 1 2 4 4 4 0 SRI (Set2 Rpb1 interacting) domain Glycos_trans_3N PF02885.17 PRP74467.1 - 5.4 7.0 6.2 8.7 6.3 0.2 3.6 2 2 0 2 2 2 0 Glycosyl transferase family, helical bundle domain ECH_1 PF00378.20 PRP74468.1 - 1.3e-35 123.0 0.0 1.6e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP74468.1 - 1.7e-24 87.0 0.0 2.5e-24 86.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FANCI_S1 PF14675.6 PRP74468.1 - 0.047 13.3 0.4 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 FANCI solenoid 1 Iso_dh PF00180.20 PRP74469.1 - 1.1e-77 261.5 0.0 1.3e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rtt106_N PF18215.1 PRP74469.1 - 0.042 13.6 0.7 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain Pkinase PF00069.25 PRP74470.1 - 3.4e-67 226.6 0.4 2.9e-66 223.5 0.4 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74470.1 - 2.3e-35 122.1 0.0 4.2e-35 121.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 PRP74470.1 - 7.8e-09 36.0 0.4 1.5e-07 31.9 0.1 3.0 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase KA1 PF02149.19 PRP74470.1 - 1.2e-07 31.4 0.1 2.3e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 PRP74470.1 - 4.4e-05 22.9 0.0 7.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.11 PRP74470.1 - 0.00036 20.6 0.4 0.00075 19.6 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.22 PRP74470.1 - 0.0072 16.0 2.0 0.0095 15.6 0.3 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PRP74470.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family bZIP_1 PF00170.21 PRP74471.1 - 7e-12 45.3 10.1 7e-12 45.3 10.1 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PRP74471.1 - 1.2e-07 31.7 6.6 1.2e-07 31.7 6.6 3.2 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 PRP74471.1 - 0.011 16.2 7.9 0.011 16.2 7.9 2.3 2 1 1 3 3 3 0 bZIP Maf transcription factor DivIC PF04977.15 PRP74471.1 - 0.11 12.3 3.4 0.21 11.4 3.4 1.5 1 0 0 1 1 1 0 Septum formation initiator Shugoshin_N PF07558.11 PRP74471.1 - 0.11 12.4 0.4 0.11 12.4 0.4 2.7 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region CtIP_N PF10482.9 PRP74471.1 - 0.74 9.9 7.5 0.072 13.1 2.4 1.9 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain GAS PF13851.6 PRP74473.1 - 0.0028 17.0 6.7 0.0028 17.0 6.7 5.0 1 1 4 5 5 5 1 Growth-arrest specific micro-tubule binding DUF730 PF05325.11 PRP74473.1 - 0.016 15.2 1.2 0.016 15.2 1.2 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF730) PI3K_C2 PF00792.24 PRP74476.1 - 0.05 13.5 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 SLATT_1 PF18181.1 PRP74478.1 - 1.2 9.1 4.2 8.4 6.4 1.3 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Peptidase_M48 PF01435.18 PRP74479.1 - 0.099 12.4 1.1 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M48 Pex24p PF06398.11 PRP74479.1 - 0.57 9.1 6.0 0.86 8.5 6.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MtN3_slv PF03083.16 PRP74479.1 - 5.3 7.2 11.6 21 5.3 4.6 3.1 3 1 0 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF3629 PF12302.8 PRP74480.1 - 0.00062 19.3 0.2 0.00081 18.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3629) BBP1_C PF15272.6 PRP74480.1 - 0.015 15.1 1.5 0.019 14.8 1.5 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ARD PF03079.14 PRP74480.1 - 0.023 14.9 0.2 0.031 14.5 0.2 1.3 1 0 0 1 1 1 0 ARD/ARD' family YhdX PF17444.2 PRP74480.1 - 0.037 13.8 1.6 0.08 12.8 1.6 1.5 1 0 0 1 1 1 0 Uncharacterized YhdX-like EF-hand_7 PF13499.6 PRP74481.1 - 2.7e-06 27.7 11.7 0.028 14.9 0.1 5.3 4 2 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 PRP74481.1 - 3.4e-06 26.5 1.8 1.1 9.3 0.0 6.3 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 PRP74481.1 - 1.4e-05 24.3 0.8 0.36 10.5 0.0 5.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PRP74481.1 - 0.0016 18.3 1.9 0.086 12.7 0.0 4.0 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_13 PF17958.1 PRP74481.1 - 0.018 14.9 0.0 5.8 6.8 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain EF-hand_9 PF14658.6 PRP74481.1 - 0.031 14.6 0.0 11 6.4 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain FBA_2 PF07735.17 PRP74481.1 - 0.035 14.2 3.6 10 6.3 0.2 4.0 4 0 0 4 4 4 0 F-box associated HTH_53 PF18606.1 PRP74482.1 - 0.06 13.0 1.8 0.072 12.8 0.5 1.7 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain DUF2341 PF10102.9 PRP74485.1 - 0.055 14.0 0.0 0.077 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) HEAT PF02985.22 PRP74487.1 - 8.3e-16 56.7 12.7 0.058 13.7 0.0 9.1 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.6 PRP74487.1 - 1.2e-10 41.7 0.2 0.91 10.1 0.1 7.2 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 PRP74487.1 - 5e-09 36.4 0.0 0.0019 18.6 0.0 5.5 3 1 2 5 5 5 2 HEAT repeats Cnd1 PF12717.7 PRP74487.1 - 1.1e-08 35.3 0.0 0.028 14.5 0.0 4.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PRP74487.1 - 6.7e-08 33.0 3.5 5.8 7.6 0.0 7.0 6 3 3 9 9 8 3 Vacuolar 14 Fab1-binding region LRR_8 PF13855.6 PRP74487.1 - 8.5e-06 25.5 17.6 0.00092 18.9 4.6 4.3 2 1 3 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 PRP74487.1 - 8.3e-05 22.9 4.9 8.3e-05 22.9 4.9 4.3 4 1 0 4 4 3 1 Leucine Rich repeats (2 copies) UME PF08064.13 PRP74487.1 - 0.00017 21.4 0.0 1.7 8.6 0.0 4.3 3 1 1 4 4 4 2 UME (NUC010) domain ParcG PF10274.9 PRP74487.1 - 0.00063 19.9 0.0 0.69 10.0 0.0 3.8 3 1 0 3 3 3 1 Parkin co-regulated protein CLASP_N PF12348.8 PRP74487.1 - 0.0029 17.2 0.0 9.5 5.7 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal MMS19_N PF14500.6 PRP74487.1 - 0.04 13.5 0.0 76 2.7 0.0 4.1 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II DRIM PF07539.12 PRP74487.1 - 0.044 12.1 0.1 0.6 8.3 0.0 2.6 2 2 1 3 3 3 0 Down-regulated in metastasis MMS19_C PF12460.8 PRP74487.1 - 0.081 12.0 0.6 3.1 6.8 0.0 2.9 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal BAF250_C PF12031.8 PRP74487.1 - 0.14 11.5 0.1 1.1 8.5 0.0 2.4 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa DUF2654 PF10849.8 PRP74489.1 - 0.057 13.6 0.1 0.077 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) RE_Bsp6I PF09504.10 PRP74492.1 - 0.0089 15.6 0.0 0.0096 15.5 0.0 1.1 1 0 0 1 1 1 1 Bsp6I restriction endonuclease LEA_4 PF02987.16 PRP74494.1 - 9.4e-62 204.9 269.0 3.3e-05 23.9 9.2 20.0 6 3 11 20 20 20 18 Late embryogenesis abundant protein YtxH PF12732.7 PRP74494.1 - 1.9e-20 73.1 209.1 0.004 17.7 10.8 14.4 3 3 6 9 9 9 5 YtxH-like protein Apolipoprotein PF01442.18 PRP74494.1 - 6e-20 71.9 160.9 7.8e-07 29.2 32.7 6.9 4 2 3 7 7 7 5 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 PRP74494.1 - 1.8e-06 28.4 161.1 0.45 11.1 6.3 14.0 5 3 10 15 15 15 11 Bacterial protein of unknown function (DUF883) VID27 PF08553.10 PRP74495.1 - 2.3e-78 263.8 0.2 7.3e-57 193.0 0.0 2.2 2 0 0 2 2 2 2 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 PRP74495.1 - 8.5e-09 35.7 2.6 1.6e-08 34.8 0.9 2.2 2 1 0 2 2 2 1 VID27 PH-like domain VID27_N PF17748.1 PRP74495.1 - 0.021 14.7 0.1 0.021 14.7 0.1 3.8 4 1 1 5 5 5 0 VID27 N-terminal region BRCA2 PF00634.18 PRP74499.1 - 0.08 12.6 1.5 7.5 6.3 0.1 2.2 2 0 0 2 2 2 0 BRCA2 repeat zf-4CXXC_R1 PF10497.9 PRP74503.1 - 0.0016 18.7 13.1 0.0026 17.9 13.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Aquarius_N PF16399.5 PRP74504.1 - 0.064 11.3 0.2 1.2 7.0 0.1 2.0 1 1 1 2 2 2 0 Intron-binding protein aquarius N-terminus IncFII_repA PF02387.15 PRP74505.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.4 2 0 0 2 2 2 0 IncFII RepA protein family DUF4661 PF15576.6 PRP74506.1 - 0.0064 16.4 0.8 0.0079 16.1 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4661) Presenilin PF01080.17 PRP74506.1 - 0.03 13.1 1.1 0.042 12.6 1.1 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 PRP74506.1 - 1.4 7.4 7.5 1.5 7.3 7.5 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 PRP74511.1 - 0.046 12.9 2.8 0.057 12.6 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_L PF01193.24 PRP74512.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain KRBA1 PF15287.6 PRP74514.1 - 0.046 13.4 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 KRBA1 family repeat DUF3824 PF12868.7 PRP74515.1 - 0.21 12.3 7.6 0.37 11.5 7.6 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) TRP PF06011.12 PRP74516.1 - 0.0036 16.1 0.1 0.0054 15.5 0.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel PhoQ_Sensor PF08918.10 PRP74516.1 - 0.012 15.4 0.8 0.012 15.4 0.8 1.9 2 1 0 2 2 2 0 PhoQ Sensor Iso_dh PF00180.20 PRP74517.1 - 0.019 14.1 2.1 1.1 8.3 0.5 2.3 2 0 0 2 2 2 0 Isocitrate/isopropylmalate dehydrogenase FlhE PF06366.13 PRP74517.1 - 1.5 8.8 6.1 14 5.8 0.8 2.8 3 0 0 3 3 3 0 Flagellar protein FlhE Peptidase_C50 PF03568.17 PRP74519.1 - 1.3e-27 96.9 0.0 1.7e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C50 Sterile PF03015.19 PRP74519.1 - 0.13 12.5 0.4 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 Male sterility protein TPR_MalT PF17874.1 PRP74520.1 - 0.019 14.3 3.3 0.037 13.4 1.1 2.2 2 0 0 2 2 2 0 MalT-like TPR region DUF5572 PF17733.1 PRP74520.1 - 0.061 13.2 0.2 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5572) Cytochrome_CBB3 PF13442.6 PRP74526.1 - 0.13 12.6 0.2 0.36 11.2 0.2 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III RhoGEF PF00621.20 PRP74527.1 - 3e-39 135.1 3.7 3e-39 135.1 3.7 1.7 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 PRP74527.1 - 1.7e-06 28.5 2.4 9.8e-06 26.0 0.4 2.5 1 1 1 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 PRP74527.1 - 2.1e-05 24.5 1.7 4.4e-05 23.5 1.7 1.4 1 0 0 1 1 1 1 PH domain PH_5 PF15405.6 PRP74527.1 - 0.0032 17.6 0.7 1.5 8.9 0.1 2.7 1 1 1 2 2 2 2 Pleckstrin homology domain ELMO_CED12 PF04727.13 PRP74527.1 - 0.0043 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family PH_13 PF16652.5 PRP74527.1 - 0.006 16.4 11.8 0.098 12.5 9.2 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain RNase_H PF00075.24 PRP74528.1 - 8.7e-06 26.0 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF5486 PF17588.2 PRP74529.1 - 0.025 14.5 0.2 0.051 13.5 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5486) DNase_II PF03265.15 PRP74530.1 - 1e-05 25.0 0.3 1.4e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 Deoxyribonuclease II Smg4_UPF3 PF03467.15 PRP74531.1 - 1.3e-43 149.0 0.7 1.3e-43 149.0 0.7 3.0 3 1 1 4 4 4 1 Smg-4/UPF3 family SUIM_assoc PF16619.5 PRP74531.1 - 0.029 14.4 5.1 0.35 11.0 5.1 2.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RRM_2 PF04059.12 PRP74531.1 - 0.055 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 BRAP2 PF07576.12 PRP74531.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 PAM2 PF07145.15 PRP74531.1 - 0.11 12.2 0.1 0.11 12.2 0.1 4.0 5 0 0 5 5 5 0 Ataxin-2 C-terminal region Ferlin_C PF16165.5 PRP74531.1 - 4.3 7.3 6.7 2.3 8.2 3.1 2.3 2 0 0 2 2 2 0 Ferlin C-terminus tRNA-synt_1b PF00579.25 PRP74532.1 - 0.012 14.9 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Taeniidae_ag PF05596.11 PRP74532.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Taeniidae antigen Herpes_LP PF03363.13 PRP74532.1 - 0.081 12.7 0.0 0.09 12.6 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus leader protein zf-C2H2_4 PF13894.6 PRP74537.1 - 0.025 15.4 2.1 0.23 12.4 2.1 2.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.15 PRP74537.1 - 0.041 13.9 0.8 0.21 11.6 0.8 2.2 1 0 0 1 1 1 0 BED zinc finger rve PF00665.26 PRP74538.1 - 1.2e-36 125.5 0.0 5.4e-22 78.2 0.0 2.4 2 0 0 2 2 2 2 Integrase core domain Lipin_N PF04571.14 PRP74538.1 - 0.0011 18.9 0.2 1.4 8.9 0.1 2.4 2 0 0 2 2 2 2 lipin, N-terminal conserved region S_100 PF01023.19 PRP74538.1 - 0.0012 18.5 0.2 2.5 7.9 0.0 2.7 2 0 0 2 2 2 2 S-100/ICaBP type calcium binding domain Porin_8 PF16966.5 PRP74538.1 - 0.0058 15.7 0.7 1.8 7.5 0.1 2.2 2 0 0 2 2 2 2 Porin-like glycoporin RafY TFB6 PF17110.5 PRP74538.1 - 0.0083 15.9 0.6 4.9 6.9 0.1 2.4 2 0 0 2 2 2 2 Subunit 11 of the general transcription factor TFIIH DUF2540 PF10802.8 PRP74538.1 - 0.075 13.1 1.7 10 6.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2540) FF PF01846.19 PRP74539.1 - 0.00051 20.2 0.0 1.2 9.4 0.0 2.8 3 0 0 3 3 3 2 FF domain Rho_Binding PF08912.11 PRP74539.1 - 0.0025 18.6 5.1 0.32 11.8 0.3 3.2 2 0 0 2 2 2 1 Rho Binding C8 PF08742.11 PRP74539.1 - 0.0073 16.7 1.2 5.5 7.5 0.1 2.5 2 0 0 2 2 2 2 C8 domain Paz_1 PF18349.1 PRP74539.1 - 0.01 15.7 0.0 8 6.5 0.0 2.4 2 0 0 2 2 2 0 PAZ domain Linker_histone PF00538.19 PRP74539.1 - 0.018 15.4 4.4 22 5.5 0.1 4.3 2 2 2 4 4 4 0 linker histone H1 and H5 family GATase_2 PF00310.21 PRP74539.1 - 0.023 13.4 2.2 2.5 6.7 0.1 2.5 2 1 0 2 2 2 0 Glutamine amidotransferases class-II Caerin_1 PF07440.12 PRP74539.1 - 0.025 14.7 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Caerin 1 protein Dynamin_M PF01031.20 PRP74539.1 - 0.031 13.5 3.0 0.25 10.5 0.3 2.2 2 0 0 2 2 2 0 Dynamin central region CRISPR_Cas9_WED PF18061.1 PRP74539.1 - 0.045 13.8 8.8 1.4 9.0 0.6 3.0 3 0 0 3 3 3 0 CRISPR-Cas9 WED domain FOXP-CC PF16159.5 PRP74539.1 - 0.046 14.3 4.3 5.6 7.7 0.4 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain MPM1 PF17234.2 PRP74539.1 - 0.075 13.3 7.7 1.9 8.7 0.9 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF535 PF04393.13 PRP74539.1 - 0.076 12.3 3.1 4.7 6.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF535) MHB PF16525.5 PRP74539.1 - 0.082 13.2 9.1 6.4 7.1 1.1 3.7 3 1 0 3 3 3 0 Haemophore, haem-binding DUF3420 PF11900.8 PRP74539.1 - 0.088 13.0 0.1 26 5.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3420) RPN6_N PF18055.1 PRP74539.1 - 0.16 12.3 2.9 12 6.3 0.2 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain ddrB-ParB PF18763.1 PRP74539.1 - 0.24 11.5 4.6 6.4 6.9 0.8 2.7 2 0 0 2 2 2 0 ddrB-like ParB superfamily domain APAF1_C PF17908.1 PRP74539.1 - 0.33 10.9 4.6 9 6.3 0.3 2.5 2 0 0 2 2 2 0 APAF-1 helical domain Mt_ATP-synt_B PF05405.14 PRP74539.1 - 1.8 8.2 12.5 4.3 7.0 2.7 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) MRP-S26 PF14943.6 PRP74540.1 - 0.28 11.1 14.6 0.39 10.6 14.6 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DcrB PF08786.11 PRP74540.1 - 0.45 10.6 3.1 0.66 10.1 2.7 1.5 1 1 0 1 1 1 0 DcrB OrfB_IS605 PF01385.19 PRP74541.1 - 0.048 13.9 0.3 0.054 13.7 0.3 1.1 1 0 0 1 1 1 0 Probable transposase rve PF00665.26 PRP74544.1 - 2.7e-11 43.7 0.0 4.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Methyltr_RsmF_N PF17125.5 PRP74545.1 - 0.075 13.5 0.1 0.54 10.8 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF DUF4286 PF14114.6 PRP74545.1 - 2.7 8.5 5.3 0.66 10.5 0.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4286) zf-trcl PF13451.6 PRP74545.1 - 6.7 6.7 11.9 30 4.6 7.4 2.6 2 0 0 2 2 2 0 Probable zinc-ribbon domain Dopey_N PF04118.14 PRP74553.1 - 0.017 14.3 0.1 0.037 13.1 0.1 1.5 1 0 0 1 1 1 0 Dopey, N-terminal DUF3106 PF11304.8 PRP74553.1 - 0.56 10.7 6.2 1.6 9.3 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) DUF3984 PF13136.6 PRP74554.1 - 0.022 14.2 2.3 0.029 13.8 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) TrfA PF07042.11 PRP74555.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 TrfA protein Pro-rich PF15240.6 PRP74556.1 - 0.0079 16.5 31.2 0.01 16.2 31.2 1.2 1 0 0 1 1 1 1 Proline-rich DUF4852 PF16144.5 PRP74557.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) GTP_EFTU PF00009.27 PRP74558.1 - 0.00039 20.0 0.0 0.00054 19.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain zf-CCHC PF00098.23 PRP74559.1 - 0.0013 18.8 3.9 0.0024 17.9 3.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PRP74559.1 - 0.06 13.2 3.9 0.1 12.4 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4254 PF14063.6 PRP74559.1 - 0.11 12.3 2.7 2.5 7.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) WDCP PF15390.6 PRP74559.1 - 0.13 10.7 1.1 0.21 9.9 1.1 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family dsDNA_bind PF01984.20 PRP74559.1 - 0.23 11.8 2.5 0.23 11.8 0.0 2.2 3 0 0 3 3 3 0 Double-stranded DNA-binding domain DUF4140 PF13600.6 PRP74559.1 - 3.3 8.2 9.9 1.6 9.2 0.1 3.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LRR_6 PF13516.6 PRP74561.1 - 9.1e-12 44.0 11.3 0.081 13.0 0.0 8.4 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 PRP74561.1 - 5.2e-11 42.6 17.7 0.044 14.2 0.3 6.8 4 3 3 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PRP74561.1 - 1.7e-07 31.0 0.2 4.4e-07 29.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PRP74561.1 - 2.2e-05 24.1 20.8 9.5e-05 22.1 0.3 5.1 6 0 0 6 6 6 2 Leucine rich repeat F-box PF00646.33 PRP74561.1 - 0.0026 17.6 1.9 0.0026 17.6 1.9 2.5 2 1 0 2 2 2 1 F-box domain LRR_1 PF00560.33 PRP74561.1 - 0.14 12.8 16.8 57 4.8 0.0 7.9 7 1 0 7 7 7 0 Leucine Rich Repeat Cupin_8 PF13621.6 PRP74563.1 - 5.1e-14 52.6 4.0 8.4e-09 35.5 3.7 3.2 2 1 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 PRP74563.1 - 1.2e-05 24.9 0.1 2e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PRP74563.1 - 0.056 13.9 0.2 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase Chromo PF00385.24 PRP74564.1 - 1.1e-13 50.9 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP74564.1 - 0.023 14.9 0.3 0.039 14.1 0.3 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Gag_spuma PF03276.14 PRP74567.1 - 0.037 12.5 0.7 0.042 12.3 0.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein F-box-like PF12937.7 PRP74569.1 - 0.00087 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP74569.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 F-box domain F-box PF00646.33 PRP74570.1 - 4.8e-05 23.1 0.1 0.00012 21.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 PRP74570.1 - 0.00036 21.0 0.1 0.62 10.7 0.0 4.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP74570.1 - 0.0033 17.3 0.3 0.0067 16.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like Ank_3 PF13606.6 PRP74570.1 - 0.017 15.6 0.0 55 4.8 0.0 5.3 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 PRP74570.1 - 0.047 14.3 0.0 9.7 6.9 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) ADH_zinc_N PF00107.26 PRP74571.1 - 2.1e-17 63.3 0.0 3.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP74571.1 - 3.8e-14 53.9 0.0 9.3e-14 52.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP74571.1 - 9.9e-11 41.5 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KTI12 PF08433.10 PRP74572.1 - 2.8e-14 53.2 1.0 8.9e-13 48.3 1.0 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 PRP74572.1 - 1.7e-05 25.0 0.0 0.0065 16.6 0.0 2.9 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 PRP74572.1 - 0.0011 19.5 0.9 0.0021 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain F-box PF00646.33 PRP74572.1 - 0.0012 18.7 1.8 0.002 18.0 0.5 2.1 2 0 0 2 2 2 1 F-box domain AAA_16 PF13191.6 PRP74572.1 - 0.0029 18.0 0.0 0.0089 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 PRP74572.1 - 0.069 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA PF00004.29 PRP74572.1 - 0.069 13.6 0.0 0.61 10.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP74572.1 - 0.15 12.3 0.2 0.9 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ydc2-catalyt PF09159.10 PRP74573.1 - 0.0041 16.9 0.2 0.005 16.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Vitellogenin_N PF01347.22 PRP74573.1 - 0.046 12.1 0.2 0.054 11.9 0.2 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region CSN5_C PF18323.1 PRP74573.1 - 0.055 14.4 0.2 0.13 13.2 0.2 1.6 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF2407_C PF13373.6 PRP74573.1 - 0.069 13.3 0.0 0.091 12.9 0.0 1.4 1 1 0 1 1 1 0 DUF2407 C-terminal domain DUF3021 PF11457.8 PRP74573.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) B12D PF06522.11 PRP74573.1 - 0.1 12.4 0.1 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PgaD PF13994.6 PRP74573.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Semialdhyde_dhC PF02774.18 PRP74577.1 - 1.5e-38 132.7 0.0 2e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 PRP74577.1 - 3.9e-32 111.2 0.0 6.4e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 PRP74577.1 - 2e-05 24.2 0.2 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 2 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 PRP74577.1 - 0.0045 17.7 0.1 0.015 16.0 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 PRP74577.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RWD PF05773.22 PRP74578.1 - 8.8e-18 64.7 0.1 2.3e-17 63.4 0.1 1.8 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 PRP74578.1 - 5.9e-08 33.1 3.2 1.3e-07 32.0 3.2 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 VID27 PF08553.10 PRP74580.1 - 3.8e-11 42.6 0.0 5.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Thx PF17070.5 PRP74585.1 - 0.085 13.0 0.7 3.9 7.7 0.0 2.7 2 0 0 2 2 2 0 30S ribosomal protein Thx RT_RNaseH PF17917.1 PRP74586.1 - 7.2e-62 206.2 0.1 2.1e-33 114.7 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP74586.1 - 8.9e-45 150.8 0.0 4.8e-30 103.5 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP74586.1 - 1.4e-23 83.6 0.4 2.6e-23 82.7 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 PRP74586.1 - 4e-22 78.1 0.6 1.2e-21 76.5 0.6 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP74586.1 - 1.9e-13 50.7 0.8 9.7e-12 45.1 0.0 3.7 4 0 0 4 4 4 1 Integrase core domain Chromo PF00385.24 PRP74586.1 - 1.6e-11 43.9 0.1 1.2e-10 41.1 0.1 2.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 PRP74586.1 - 8.6e-05 22.7 0.1 0.00026 21.1 0.1 1.9 1 0 0 1 1 1 1 H2C2 zinc finger DUF1712 PF08217.11 PRP74586.1 - 0.0012 17.4 0.1 1.1 7.6 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) DUF5024 PF16427.5 PRP74586.1 - 0.012 15.9 0.1 7.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) RVT_3 PF13456.6 PRP74586.1 - 0.026 14.3 0.3 7.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Reverse transcriptase-like GatB_Yqey PF02637.18 PRP74586.1 - 0.082 12.8 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 GatB domain LST1 PF05083.13 PRP74588.1 - 7.8 6.9 7.1 0.75 10.1 0.3 3.0 2 0 0 2 2 2 0 LST-1 protein zf-met PF12874.7 PRP74590.1 - 0.00064 20.0 2.6 17 6.0 0.1 3.8 3 0 0 3 3 3 3 Zinc-finger of C2H2 type Pantoate_ligase PF02569.15 PRP74590.1 - 0.06 12.6 5.1 17 4.6 0.1 3.2 3 0 0 3 3 3 0 Pantoate-beta-alanine ligase PilJ_C PF18223.1 PRP74590.1 - 0.1 13.1 2.2 4.1 8.0 0.1 3.0 3 0 0 3 3 3 0 Pili PilJ C-terminal domain AreA_N PF07573.11 PRP74590.1 - 0.41 11.3 2.3 99 3.7 0.0 3.6 3 0 0 3 3 3 0 Nitrogen regulatory protein AreA N terminus 4HPAD_g_N PF18671.1 PRP74590.1 - 0.94 9.2 2.8 1.2e+02 2.6 0.1 3.5 3 0 0 3 3 3 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal RT_RNaseH PF17917.1 PRP74592.1 - 4.5e-35 120.1 0.0 9.5e-35 119.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 PRP74592.1 - 4.3e-32 110.8 0.5 5.7e-15 55.5 0.1 3.1 3 0 0 3 3 3 2 Integrase core domain Integrase_H2C2 PF17921.1 PRP74592.1 - 2.1e-31 107.8 9.4 4.4e-21 74.8 1.1 2.7 2 0 0 2 2 2 2 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 PRP74592.1 - 1.5e-30 105.2 0.0 3.3e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP74592.1 - 5.3e-18 65.4 0.1 1e-17 64.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 PRP74592.1 - 8.6e-13 48.7 0.0 0.0033 18.0 0.0 4.0 3 0 0 3 3 3 3 Aspartyl protease gag-asp_proteas PF13975.6 PRP74592.1 - 1.6e-12 47.8 0.0 0.0013 19.2 0.0 3.8 3 0 0 3 3 3 3 gag-polyprotein putative aspartyl protease Chromo PF00385.24 PRP74592.1 - 7.6e-12 45.0 0.0 2.5e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 PRP74592.1 - 4e-09 36.5 2.3 6.2e-06 26.3 0.1 2.7 2 0 0 2 2 2 2 H2C2 zinc finger RVP_2 PF08284.11 PRP74592.1 - 0.00016 21.4 0.0 9.3 6.0 0.0 4.5 4 1 0 4 4 4 1 Retroviral aspartyl protease Peptidase_A2E PF12382.8 PRP74592.1 - 0.00054 20.0 0.0 26 4.8 0.0 4.2 4 0 0 4 4 4 0 Retrotransposon peptidase MBOAT_2 PF13813.6 PRP74592.1 - 0.004 17.4 2.1 4.3 7.7 0.2 3.1 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family CAP PF00188.26 PRP74592.1 - 0.012 16.5 1.4 14 6.5 0.0 3.8 4 0 0 4 4 2 0 Cysteine-rich secretory protein family rve_3 PF13683.6 PRP74592.1 - 0.019 14.7 0.5 15 5.4 0.0 3.4 3 0 0 3 3 3 0 Integrase core domain Ferrochelatase PF00762.19 PRP74592.1 - 0.022 13.8 0.1 7 5.6 0.0 2.4 2 0 0 2 2 2 0 Ferrochelatase DUF4124 PF13511.6 PRP74592.1 - 0.029 14.7 0.0 16 5.9 0.0 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Arf PF00025.21 PRP74592.1 - 0.12 11.8 2.2 0.54 9.7 0.0 3.3 6 0 0 6 6 6 0 ADP-ribosylation factor family DUF3945 PF13101.6 PRP74592.1 - 0.31 10.8 2.4 22 4.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) F5_F8_type_C PF00754.25 PRP74595.1 - 0.0071 16.5 0.0 0.09 12.9 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Sad1_UNC PF07738.13 PRP74595.1 - 0.024 14.6 0.3 0.14 12.2 0.0 2.5 3 0 0 3 3 3 0 Sad1 / UNC-like C-terminal CpXC PF14353.6 PRP74595.1 - 0.036 14.1 0.1 0.088 12.9 0.1 1.7 1 0 0 1 1 1 0 CpXC protein UPF0547 PF10571.9 PRP74595.1 - 0.062 13.4 1.7 0.15 12.1 1.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF4451 PF14616.6 PRP74595.1 - 0.15 12.2 1.4 0.68 10.2 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) DZR PF12773.7 PRP74595.1 - 0.25 11.4 0.8 0.48 10.5 0.8 1.4 1 0 0 1 1 1 0 Double zinc ribbon PH PF00169.29 PRP74596.1 - 2.1e-06 28.2 0.0 4.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP74596.1 - 0.0002 21.8 0.0 0.0019 18.6 0.0 2.8 1 0 0 1 1 1 1 Pleckstrin homology domain I_LWEQ PF01608.17 PRP74596.1 - 0.00048 20.4 8.0 0.00048 20.4 8.0 7.3 3 2 5 8 8 8 4 I/LWEQ domain A_deaminase_N PF08451.11 PRP74596.1 - 0.063 13.6 0.5 0.2 12.0 0.5 1.9 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal PH_3 PF14593.6 PRP74596.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 PH domain Ku_PK_bind PF08785.11 PRP74596.1 - 0.65 10.1 12.6 6.1 7.0 0.1 4.9 5 0 0 5 5 5 0 Ku C terminal domain like PAS_10 PF13596.6 PRP74596.1 - 9 7.0 7.7 3.8 8.1 0.1 4.2 5 0 0 5 5 5 0 PAS domain GYF PF02213.16 PRP74597.1 - 3e-12 46.0 1.6 6.5e-12 44.9 1.6 1.6 1 0 0 1 1 1 1 GYF domain Pox_G5 PF04599.12 PRP74597.1 - 1.1 8.2 3.9 1.9 7.4 3.9 1.3 1 0 0 1 1 1 0 Poxvirus G5 protein PPR_3 PF13812.6 PRP74598.1 - 3.3e-09 36.7 0.0 4.4e-05 23.5 0.0 2.1 1 1 2 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 PRP74598.1 - 4e-06 26.9 0.1 0.024 14.8 0.0 2.9 2 1 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 PRP74598.1 - 0.049 13.0 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Hydrolase_4 PF12146.8 PRP74600.1 - 0.063 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sp38 PF07354.12 PRP74603.1 - 0.0014 18.1 4.3 0.071 12.5 0.6 2.4 2 0 0 2 2 2 2 Zona-pellucida-binding protein (Sp38) Nepo_coat_N PF03689.15 PRP74603.1 - 0.007 16.3 0.2 5.7 7.0 0.0 2.7 2 0 0 2 2 2 2 Nepovirus coat protein, N-terminal domain OrfB_Zn_ribbon PF07282.11 PRP74603.1 - 0.02 14.8 2.2 0.71 9.8 0.1 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain MPM1 PF17234.2 PRP74603.1 - 0.039 14.2 0.9 0.039 14.2 0.9 3.2 2 1 0 3 3 3 0 Mitochondrial peculiar membrane protein 1 Paz_1 PF18349.1 PRP74603.1 - 0.11 12.4 4.6 17 5.5 0.0 3.4 3 0 0 3 3 3 0 PAZ domain ER PF01133.17 PRP74603.1 - 0.19 11.8 4.9 6.8 6.8 0.4 2.8 2 0 0 2 2 2 0 Enhancer of rudimentary YqzH PF14164.6 PRP74603.1 - 0.67 10.1 6.9 7.5 6.7 0.7 2.8 2 0 0 2 2 2 0 YqzH-like protein TPD PF14811.6 PRP74603.1 - 4 7.3 13.0 1 9.2 0.8 3.0 2 1 1 3 3 3 0 Protein of unknown function TPD sequence-motif Chromo PF00385.24 PRP74604.1 - 7.1e-12 45.1 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP74604.1 - 0.27 11.4 1.1 0.35 11.1 0.1 1.7 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 ANAPC1 PF12859.7 PRP74605.1 - 3e-08 34.3 0.0 2.9e-06 27.8 0.0 3.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 PRP74605.1 - 0.51 10.9 6.4 7 7.3 0.1 2.9 3 0 0 3 3 3 0 Proteasome/cyclosome repeat Pkinase_Tyr PF07714.17 PRP74606.1 - 2.3e-27 95.9 0.0 6.1e-27 94.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74606.1 - 4e-13 49.3 0.0 1.1e-12 48.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Beta_helix PF13229.6 PRP74606.1 - 3.7e-07 30.1 53.9 4.4e-05 23.4 13.5 7.6 3 2 1 6 6 6 4 Right handed beta helix region Adeno_E3_CR2 PF02439.15 PRP74606.1 - 0.013 15.3 0.7 0.032 14.0 0.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Polysacc_deac_1 PF01522.21 PRP74607.1 - 9.8e-24 83.6 0.0 1.1e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide deacetylase TIG PF01833.24 PRP74607.1 - 1.3e-11 44.4 0.0 3e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain Siva PF05458.12 PRP74607.1 - 5.4e-06 26.2 16.5 1.1e-05 25.2 15.9 1.7 1 1 0 1 1 1 1 Cd27 binding protein (Siva) ARF7EP_C PF14949.6 PRP74607.1 - 0.022 15.4 10.3 0.039 14.6 10.3 1.3 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Zf_RING PF16744.5 PRP74607.1 - 0.33 11.1 11.6 0.85 9.8 11.6 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger 2-oxoacid_dh PF00198.23 PRP74608.1 - 5.1e-79 265.0 0.6 7.9e-79 264.4 0.6 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Pkinase PF00069.25 PRP74608.1 - 4.4e-72 242.6 0.0 7.1e-72 241.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74608.1 - 3.5e-48 164.1 0.0 6.6e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Biotin_lipoyl PF00364.22 PRP74608.1 - 4.2e-12 45.7 0.1 9e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Kdo PF06293.14 PRP74608.1 - 0.00028 20.3 0.2 0.00059 19.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP74608.1 - 0.0003 19.7 0.0 0.00068 18.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP74608.1 - 0.0064 15.8 0.0 0.021 14.1 0.0 1.9 1 0 0 1 1 1 1 Kinase-like DUF4704 PF15787.5 PRP74608.1 - 0.018 14.3 0.2 0.062 12.5 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) adh_short PF00106.25 PRP74609.1 - 3e-31 108.4 0.3 3.8e-31 108.1 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP74609.1 - 1.7e-27 96.5 1.1 2.1e-27 96.2 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP74609.1 - 6.6e-11 42.4 0.2 8.9e-11 42.0 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP74609.1 - 2.6e-07 30.4 0.3 4.2e-07 29.7 0.3 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP74609.1 - 1.3e-05 25.2 1.7 1.7e-05 24.8 1.7 1.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PRP74609.1 - 0.0002 20.9 0.5 0.00033 20.2 0.5 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Mfa_like_2 PF15415.6 PRP74609.1 - 0.0021 17.0 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Fimbrillin-like Polysacc_synt_2 PF02719.15 PRP74609.1 - 0.075 12.2 0.2 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RCC1 PF00415.18 PRP74610.1 - 1.4e-64 214.5 14.0 1.3e-10 41.7 0.2 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 PRP74610.1 - 8.2e-37 125.8 0.1 3e-23 82.2 0.2 3.2 2 1 1 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 PRP74610.1 - 2.1e-24 84.7 31.4 4e-05 23.3 0.3 8.9 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Skp1_POZ PF03931.15 PRP74610.1 - 0.001 19.2 0.0 0.082 13.1 0.0 2.4 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain SH3_9 PF14604.6 PRP74611.1 - 1e-08 34.9 0.0 2.8e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain C1_1 PF00130.22 PRP74611.1 - 4.1e-08 33.0 6.8 8e-08 32.0 6.8 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 PRP74611.1 - 3.3e-06 26.6 0.0 8.3e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP74611.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Perilipin PF03036.16 PRP74611.1 - 0.037 13.0 0.9 0.052 12.6 0.9 1.2 1 0 0 1 1 1 0 Perilipin family PHD PF00628.29 PRP74611.1 - 0.088 12.7 4.8 0.2 11.6 4.8 1.6 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 PRP74611.1 - 3.4 7.3 7.9 0.71 9.5 3.4 2.1 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.25 PRP74612.1 - 5.1e-79 265.3 0.0 6.8e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74612.1 - 3.2e-39 134.8 0.0 4.6e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP74612.1 - 2.5e-06 27.0 0.0 6.9e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PRP74612.1 - 0.00054 18.8 0.0 0.00098 18.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP74612.1 - 0.00087 18.3 0.8 0.0013 17.7 0.8 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DEC-1_N PF04625.13 PRP74612.1 - 0.006 15.6 0.7 0.0097 15.0 0.7 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region APH PF01636.23 PRP74612.1 - 0.0083 16.1 0.0 0.31 10.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PRP74612.1 - 0.085 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 V-SNARE_C PF12352.8 PRP74613.1 - 1.9e-06 28.0 0.3 4.7e-06 26.8 0.2 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PRP74613.1 - 7.3e-06 25.8 0.4 7.3e-06 25.8 0.4 2.4 2 1 0 2 2 2 1 Sec20 V-SNARE PF05008.15 PRP74613.1 - 0.00043 20.6 3.8 0.00043 20.6 3.8 3.1 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus FeoB_associated PF12669.7 PRP74613.1 - 0.012 16.0 1.4 0.022 15.2 1.4 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Tup_N PF08581.10 PRP74613.1 - 0.082 13.2 0.1 0.082 13.2 0.1 2.8 1 1 1 3 3 3 0 Tup N-terminal BCDHK_Adom3 PF10436.9 PRP74613.1 - 3 7.7 6.3 4 7.2 4.7 1.9 1 1 1 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase EMP24_GP25L PF01105.24 PRP74613.1 - 8.2 6.3 8.8 8.9 6.2 2.2 2.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 PRP74614.1 - 1.4e-61 208.2 0.0 1.4e-61 208.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74614.1 - 1.8e-42 145.5 0.0 1.8e-42 145.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP74614.1 - 3.8e-07 29.4 0.3 7.5e-07 28.4 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PRP74614.1 - 7.7e-05 22.1 0.0 0.00077 18.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP74614.1 - 0.0009 18.6 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP74614.1 - 0.027 13.3 0.9 0.14 10.9 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase YAF2_RYBP PF17219.3 PRP74615.1 - 0.091 12.4 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Yaf2/RYBP C-terminal binding motif ATG27 PF09451.10 PRP74617.1 - 2.8e-12 47.1 0.1 1.3e-11 44.9 0.1 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 PRP74617.1 - 3.3e-11 42.8 0.1 1.4e-10 40.7 0.1 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate receptor CIMR PF00878.18 PRP74617.1 - 0.0028 17.7 0.0 1.4 9.0 0.1 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Amnionless PF14828.6 PRP74617.1 - 0.16 10.7 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless FeoB_C PF07664.12 PRP74617.1 - 0.39 10.5 1.6 0.85 9.4 1.6 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus OAD_gamma PF04277.13 PRP74617.1 - 0.39 11.3 1.6 0.81 10.3 1.6 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Man-6-P_recep PF02157.15 PRP74618.1 - 1.1e-13 50.8 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 PRP74618.1 - 2.9e-13 50.3 0.0 4.4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Snf7 PF03357.21 PRP74619.1 - 4.7e-41 140.3 17.8 6.4e-41 139.8 17.8 1.1 1 0 0 1 1 1 1 Snf7 CCDC24 PF15669.5 PRP74619.1 - 0.0056 16.6 1.8 0.0056 16.6 1.8 1.8 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family LppC PF04348.13 PRP74619.1 - 0.1 11.4 5.9 0.12 11.2 5.9 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein NPR2 PF06218.11 PRP74619.1 - 2.2 6.9 6.1 0.94 8.2 1.1 2.0 1 1 1 2 2 2 0 Nitrogen permease regulator 2 DUF2890 PF11081.8 PRP74619.1 - 4.1 7.5 7.3 11 6.1 0.2 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2890) Pro-kuma_activ PF09286.11 PRP74620.1 - 1.7e-21 77.0 0.1 3.6e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP74620.1 - 0.0041 16.4 4.3 0.01 15.1 4.3 1.8 1 0 0 1 1 1 1 Subtilase family PGAP1 PF07819.13 PRP74622.1 - 1.7e-72 243.9 1.5 2.6e-72 243.3 0.3 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 PRP74622.1 - 2.9e-05 24.8 0.0 5.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 PRP74622.1 - 0.00032 20.6 0.0 0.00061 19.7 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 PRP74622.1 - 0.0024 17.5 0.1 0.0069 16.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 PRP74622.1 - 0.0039 16.4 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 PRP74622.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP74622.1 - 0.032 13.5 0.0 0.066 12.5 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 PRP74622.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3572 PF12096.8 PRP74622.1 - 0.071 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) DUF915 PF06028.11 PRP74622.1 - 0.14 11.4 0.0 0.52 9.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) WGG PF10273.9 PRP74624.1 - 7.1e-18 65.1 0.1 1.2e-17 64.3 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RhoGAP PF00620.27 PRP74626.1 - 7.6e-44 149.2 0.0 1.6e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain UPF0061 PF02696.14 PRP74626.1 - 0.0057 15.5 0.0 0.0099 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family INTS5_N PF14837.6 PRP74626.1 - 0.014 15.0 0.1 0.029 14.0 0.1 1.4 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus DUF1708 PF08101.11 PRP74626.1 - 0.027 13.6 0.1 0.062 12.4 0.0 1.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1708) DUF4131 PF13567.6 PRP74627.1 - 0.0095 15.6 3.4 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) S_4TM PF18159.1 PRP74627.1 - 0.072 12.4 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain EOS1 PF12326.8 PRP74627.1 - 0.077 12.9 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 N-glycosylation protein DUF4407 PF14362.6 PRP74628.1 - 3.2 7.0 18.4 6.7 6.0 18.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1043 PF06295.12 PRP74628.1 - 3.6 7.6 14.3 0.34 10.9 0.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) AAA_13 PF13166.6 PRP74628.1 - 3.6 6.1 26.2 75 1.8 26.2 2.4 1 1 0 1 1 1 0 AAA domain Lebercilin PF15619.6 PRP74628.1 - 4.4 6.9 43.8 0.061 13.0 32.1 3.1 2 2 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF948 PF06103.11 PRP74628.1 - 6.2 7.1 7.9 4.6 7.6 1.4 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Peptidase_S46 PF10459.9 PRP74628.1 - 8.2 4.9 19.3 13 4.2 19.3 1.2 1 0 0 1 1 1 0 Peptidase S46 Rep_fac_C PF08542.11 PRP74629.1 - 3.4e-24 85.1 0.1 9.3e-24 83.7 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 PRP74629.1 - 2.7e-13 50.0 0.1 1.5e-10 41.1 0.1 2.9 2 1 1 3 3 3 1 DNA polymerase III, delta subunit AAA PF00004.29 PRP74629.1 - 9.5e-13 48.7 0.0 2.3e-12 47.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 PRP74629.1 - 3.1e-06 27.2 0.0 6.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP74629.1 - 1e-05 26.0 0.0 0.00057 20.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 PRP74629.1 - 1.3e-05 25.2 0.0 3.5e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 PRP74629.1 - 1.4e-05 25.3 0.2 0.0088 16.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PRP74629.1 - 2e-05 24.1 0.1 0.00043 19.7 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 PRP74629.1 - 5.1e-05 23.2 0.2 6.9e-05 22.8 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PRP74629.1 - 6.4e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PRP74629.1 - 0.0003 20.6 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TniB PF05621.11 PRP74629.1 - 0.0003 20.2 0.1 0.79 9.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein RuvB_N PF05496.12 PRP74629.1 - 0.0015 18.3 0.0 0.0046 16.7 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 PRP74629.1 - 0.005 16.6 0.2 0.25 11.1 0.0 2.7 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PRP74629.1 - 0.0052 17.1 0.5 0.026 14.8 0.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 PRP74629.1 - 0.0055 17.0 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 1 1 AAA C-terminal domain AAA_5 PF07728.14 PRP74629.1 - 0.0056 16.7 0.0 0.019 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) MipZ PF09140.11 PRP74629.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ RNA_helicase PF00910.22 PRP74629.1 - 0.019 15.3 0.1 0.25 11.7 0.0 2.7 2 1 0 2 2 2 0 RNA helicase DUF309 PF03745.14 PRP74629.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF309) NTPase_1 PF03266.15 PRP74629.1 - 0.026 14.5 0.7 0.24 11.3 0.1 2.4 1 1 1 2 2 2 0 NTPase ATPase_2 PF01637.18 PRP74629.1 - 0.031 14.2 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 PRP74629.1 - 0.033 14.7 0.0 0.081 13.4 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 PRP74629.1 - 0.043 13.4 0.3 0.59 9.7 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_3 PF07726.11 PRP74629.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PRP74629.1 - 0.072 12.8 0.1 0.3 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PRP74629.1 - 0.072 13.3 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 PRP74629.1 - 0.076 12.0 0.0 0.18 10.7 0.0 1.6 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 PRP74629.1 - 0.092 12.5 0.3 0.44 10.3 0.1 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein PP2C PF00481.21 PRP74630.1 - 5.2e-64 216.3 0.0 7.9e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 PRP74630.1 - 1.6e-19 69.7 54.3 8.3e-07 29.2 3.8 10.7 4 3 9 15 15 15 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP74630.1 - 3.8e-14 51.5 48.3 0.49 10.6 0.1 15.8 18 0 0 18 18 18 6 Leucine Rich repeat LRR_8 PF13855.6 PRP74630.1 - 2.4e-10 40.0 12.1 3.1e-07 30.0 3.9 7.4 5 2 2 9 9 9 2 Leucine rich repeat FERM_f0 PF16511.5 PRP74630.1 - 1e-08 35.3 0.1 3e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM LRR_1 PF00560.33 PRP74630.1 - 3.5e-05 23.7 48.8 1.6 9.6 0.2 15.1 13 3 1 14 14 14 3 Leucine Rich Repeat LRR_9 PF14580.6 PRP74630.1 - 0.00016 21.3 5.5 0.004 16.7 2.0 2.7 1 1 1 2 2 2 2 Leucine-rich repeat F-box-like PF12937.7 PRP74630.1 - 0.015 15.2 0.1 0.073 13.0 0.1 2.3 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 PRP74630.1 - 0.029 14.3 1.1 0.12 12.3 1.1 2.2 1 0 0 1 1 1 0 F-box domain FNIP PF05725.12 PRP74630.1 - 0.51 10.5 9.1 2.9 8.1 0.0 5.6 5 2 0 5 5 5 0 FNIP Repeat GCV_H PF01597.19 PRP74631.1 - 3.9e-08 33.2 0.0 2.4e-07 30.7 0.0 1.9 1 1 1 2 2 2 1 Glycine cleavage H-protein WHAMM-JMY_N PF15920.5 PRP74631.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated Complex1_LYR PF05347.15 PRP74632.1 - 3e-09 36.8 0.7 8.5e-09 35.3 0.7 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) CTU2 PF10288.9 PRP74633.1 - 1.1e-09 38.5 0.2 1.1e-09 38.5 0.2 2.1 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 PRP74633.1 - 0.0035 17.1 0.0 0.0074 16.1 0.0 1.5 1 1 0 1 1 1 1 PP-loop family DUF2242 PF10001.9 PRP74634.1 - 0.25 11.5 1.9 0.51 10.5 0.8 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2242) WD40 PF00400.32 PRP74635.1 - 2e-63 208.8 23.2 3.1e-11 43.6 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 PRP74635.1 - 4.9e-25 87.6 8.4 7e-25 87.1 8.4 1.2 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 PRP74635.1 - 1.1e-23 83.3 0.1 7.7e-06 26.1 0.0 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP74635.1 - 2e-11 43.4 3.8 0.065 12.2 0.0 6.3 2 1 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PRP74635.1 - 1.1e-09 38.1 0.0 0.0058 16.0 0.0 4.9 5 0 0 5 5 5 2 WD40-like domain eIF2A PF08662.11 PRP74635.1 - 2.1e-05 24.5 0.0 0.65 9.8 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PRP74635.1 - 2.4e-05 24.1 0.9 3.9 7.5 0.1 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 PRP74635.1 - 5.8e-05 21.9 0.1 4.2 5.9 0.0 4.4 3 1 2 5 5 5 1 Nucleoporin Nup120/160 Frtz PF11768.8 PRP74635.1 - 0.0014 17.1 0.0 0.48 8.7 0.0 3.0 4 0 0 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 PRP74635.1 - 0.0016 17.0 0.6 0.13 10.8 0.0 3.1 1 1 4 5 5 5 1 Cytochrome D1 heme domain Nbas_N PF15492.6 PRP74635.1 - 0.0017 17.7 0.4 4.8 6.4 0.1 3.7 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF3450 PF11932.8 PRP74635.1 - 0.007 15.7 2.1 0.011 15.1 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Proteasome_A_N PF10584.9 PRP74635.1 - 0.068 12.9 3.4 2.7 7.8 0.0 4.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature SHE3 PF17078.5 PRP74635.1 - 0.091 12.5 4.1 0.14 11.8 4.1 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 OmpH PF03938.14 PRP74635.1 - 0.19 12.1 3.4 0.29 11.5 3.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phage_GP20 PF06810.11 PRP74635.1 - 0.21 11.4 1.5 0.35 10.7 1.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 dCache_2 PF08269.11 PRP74635.1 - 0.54 9.4 3.5 0.88 8.7 3.5 1.2 1 0 0 1 1 1 0 Cache domain CC2-LZ PF16516.5 PRP74635.1 - 0.71 10.3 4.5 0.74 10.2 3.1 1.7 2 0 0 2 2 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ZapB PF06005.12 PRP74635.1 - 0.75 10.3 5.6 1.4 9.4 5.6 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TMPIT PF07851.13 PRP74635.1 - 0.77 8.9 2.9 1.1 8.5 2.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein LSM PF01423.22 PRP74636.1 - 1.2e-15 56.9 0.0 1.2e-15 56.9 0.0 1.9 2 1 0 2 2 1 1 LSM domain SM-ATX PF14438.6 PRP74636.1 - 0.00016 21.8 0.0 0.00032 20.8 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain G0-G1_switch_2 PF15103.6 PRP74636.1 - 0.0014 19.1 1.1 0.0019 18.6 1.1 1.2 1 0 0 1 1 1 1 G0/G1 switch protein 2 Mpp10 PF04006.12 PRP74636.1 - 0.0056 15.2 16.4 0.0068 14.9 16.4 1.0 1 0 0 1 1 1 1 Mpp10 protein RNA_pol_3_Rpc31 PF11705.8 PRP74636.1 - 0.0069 16.7 8.8 0.0069 16.7 8.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 PRP74636.1 - 0.02 14.5 12.0 0.024 14.2 12.0 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 PRP74636.1 - 0.037 12.3 8.8 0.038 12.3 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Plexin_cytopl PF08337.12 PRP74636.1 - 0.046 12.4 1.2 0.051 12.2 1.2 1.0 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain DUF778 PF05608.12 PRP74636.1 - 0.069 13.5 3.2 0.11 12.9 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF778) RNA_pol_Rpc4 PF05132.14 PRP74636.1 - 0.07 13.6 1.0 0.066 13.6 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop14 PF04147.12 PRP74636.1 - 0.25 9.5 16.8 0.27 9.4 16.8 1.0 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 PRP74636.1 - 0.39 9.4 10.4 0.46 9.2 10.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 PRP74636.1 - 0.43 9.3 5.0 0.45 9.2 5.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 PRP74636.1 - 0.47 9.8 7.9 0.55 9.6 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Connexin PF00029.19 PRP74636.1 - 0.52 10.0 4.1 0.66 9.7 4.1 1.1 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 PRP74636.1 - 0.58 9.1 4.9 0.66 8.9 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 PRP74636.1 - 0.65 9.3 13.3 0.76 9.0 13.3 1.0 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 PRP74636.1 - 0.79 9.1 18.1 0.86 9.0 18.1 1.1 1 0 0 1 1 1 0 SDA1 MRNIP PF15749.5 PRP74636.1 - 0.82 10.4 6.8 1.1 10.0 6.8 1.2 1 0 0 1 1 1 0 MRN-interacting protein Merozoite_SPAM PF07133.11 PRP74636.1 - 1.1 9.2 37.7 1.6 8.7 37.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CobT PF06213.12 PRP74636.1 - 1.3 8.4 18.5 1.6 8.0 18.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.11 PRP74636.1 - 1.3 7.0 7.4 1.5 6.8 7.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GNAT_acetyltr_2 PF13718.6 PRP74636.1 - 1.4 8.2 5.1 1.8 7.9 5.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 NOA36 PF06524.12 PRP74636.1 - 2.4 7.4 10.8 3.2 7.0 10.8 1.3 1 0 0 1 1 1 0 NOA36 protein PTPRCAP PF15713.5 PRP74636.1 - 2.7 8.3 18.2 3.1 8.1 18.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated AIF_C PF14721.6 PRP74636.1 - 2.8 8.3 4.8 3.6 8.0 4.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EIIBC-GUT_N PF03612.14 PRP74636.1 - 3.3 7.4 6.3 4.5 7.0 6.3 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF740 PF05340.12 PRP74636.1 - 6.1 5.5 10.9 5.9 5.5 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Sel1 PF08238.12 PRP74637.1 - 1.3e-06 28.8 15.9 0.02 15.6 0.1 6.4 8 0 0 8 8 8 4 Sel1 repeat PMP1_2 PF08114.11 PRP74637.1 - 0.41 10.4 2.5 0.98 9.2 2.5 1.5 1 0 0 1 1 1 0 ATPase proteolipid family PLCC PF14466.6 PRP74637.1 - 0.47 10.6 2.1 12 6.0 0.2 2.7 2 0 0 2 2 2 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein PCI PF01399.27 PRP74638.1 - 3e-21 75.9 0.8 1.5e-20 73.7 0.0 2.6 3 0 0 3 3 3 1 PCI domain RPN5_C PF18098.1 PRP74638.1 - 1.7e-15 56.8 2.1 5e-15 55.3 2.1 1.9 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain CP12 PF02672.15 PRP74638.1 - 0.67 10.7 2.5 1.7 9.5 0.1 2.5 2 0 0 2 2 2 0 CP12 domain NblA PF04485.12 PRP74638.1 - 1.5 9.3 5.6 1.4 9.4 0.5 3.1 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA PPR_1 PF12854.7 PRP74638.1 - 4.7 7.0 4.4 6.5 6.6 0.4 2.9 3 0 0 3 3 3 0 PPR repeat NIF PF03031.18 PRP74640.1 - 8.3e-50 168.6 0.2 1.7e-49 167.6 0.2 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF2263 PF10021.9 PRP74640.1 - 9e-38 129.9 0.2 1.5e-37 129.2 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF1084 PF06454.11 PRP74641.1 - 6.5e-06 25.7 14.8 8.6e-06 25.3 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Pkinase_Tyr PF07714.17 PRP74643.1 - 6.5e-63 212.4 0.0 1.1e-62 211.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74643.1 - 6.9e-54 183.0 0.0 1.1e-53 182.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP74643.1 - 9.4e-16 57.7 0.0 2.9e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 PRP74643.1 - 0.00067 19.1 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 PRP74643.1 - 0.0011 18.0 0.1 0.75 8.7 0.1 2.6 2 0 0 2 2 2 2 Haspin like kinase domain DUF5344 PF17279.2 PRP74643.1 - 0.084 13.5 1.6 0.23 12.1 1.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5344) GAS PF13851.6 PRP74643.1 - 0.17 11.2 6.8 0.3 10.4 6.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FliT PF05400.13 PRP74643.1 - 0.89 10.4 4.1 2 9.3 4.1 1.6 1 0 0 1 1 1 0 Flagellar protein FliT Ribosomal_S5 PF00333.20 PRP74644.1 - 2.2e-29 101.2 2.3 6.1e-29 99.8 2.3 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 PRP74644.1 - 2.6e-25 87.6 0.2 4.5e-25 86.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain SNF2_N PF00176.23 PRP74645.1 - 2.2e-74 250.3 1.6 4.8e-74 249.2 1.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 PRP74645.1 - 2.6e-18 65.9 0.6 7.4e-18 64.4 0.6 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 PRP74645.1 - 1.7e-17 63.8 0.0 5.9e-17 62.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain QLQ PF08880.11 PRP74645.1 - 2.1e-10 40.1 0.8 9.3e-10 38.1 0.8 2.1 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 PRP74645.1 - 1e-09 38.6 0.0 1e-09 38.6 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SnAC PF14619.6 PRP74645.1 - 2.6e-08 34.4 3.8 2.6e-08 34.4 3.8 4.6 3 2 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 PRP74645.1 - 4.8e-08 33.2 16.9 4.8e-08 33.2 16.9 4.2 5 0 0 5 5 5 1 HSA Ribosomal_S13_N PF08069.12 PRP74645.1 - 0.01 15.9 0.0 6.3 6.9 0.0 3.3 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain DUF3837 PF12939.7 PRP74645.1 - 0.14 12.5 0.0 0.14 12.5 0.0 3.9 4 1 0 5 5 5 0 Domain of unknown function (DUF3837) Proteasome PF00227.26 PRP74646.1 - 1e-56 191.5 0.0 2.2e-56 190.4 0.0 1.5 1 1 1 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 PRP74646.1 - 1.2e-13 50.4 0.1 2.7e-13 49.3 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Glyco_hydro_71 PF03659.14 PRP74647.1 - 2e-89 300.0 13.5 3.6e-89 299.2 13.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PDCD7 PF16021.5 PRP74647.1 - 0.00057 19.1 0.1 0.00057 19.1 0.1 2.1 2 0 0 2 2 2 1 Programmed cell death protein 7 Pur_ac_phosph_N PF16656.5 PRP74647.1 - 0.0021 18.6 1.2 0.0062 17.1 0.1 2.4 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain O-antigen_lig PF13425.6 PRP74647.1 - 1.7 7.4 8.3 2.8 6.6 8.3 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Lipase_GDSL_2 PF13472.6 PRP74648.1 - 7e-13 49.4 1.6 2.3e-12 47.7 1.6 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PAN_4 PF14295.6 PRP74648.1 - 7.6e-11 41.7 2.3 7.6e-11 41.7 2.3 1.8 2 0 0 2 2 2 1 PAN domain CE2_N PF17996.1 PRP74648.1 - 2.6e-08 33.8 0.0 5.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 PRP74648.1 - 2.3e-06 27.8 0.0 6.3e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PAN_1 PF00024.26 PRP74648.1 - 0.00095 19.1 0.6 0.0017 18.2 0.6 1.4 1 0 0 1 1 1 1 PAN domain Hist_deacetyl PF00850.19 PRP74648.1 - 0.058 12.9 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain C2 PF00168.30 PRP74649.1 - 7.5e-05 23.0 3.6 0.008 16.4 0.0 4.2 5 1 0 5 5 5 2 C2 domain HATPase_c PF02518.26 PRP74650.1 - 5.2e-49 165.4 0.6 6.5e-25 87.8 0.1 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP74650.1 - 1.2e-42 144.6 0.1 3e-21 75.7 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 PRP74650.1 - 9.3e-26 89.7 5.2 3.5e-14 52.6 0.0 3.1 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP74650.1 - 1.6e-05 24.8 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 PRP74650.1 - 0.013 15.8 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 PAS fold HATPase_c_2 PF13581.6 PRP74650.1 - 0.037 14.0 0.0 4.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain DUF4404 PF14357.6 PRP74650.1 - 6.1 7.6 9.8 10 6.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Ist1 PF03398.14 PRP74651.1 - 2.3e-60 203.3 7.3 2.7e-60 203.0 7.3 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway HEAT PF02985.22 PRP74652.1 - 3e-05 23.9 0.0 0.081 13.2 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 PRP74652.1 - 0.00028 21.3 0.9 0.23 12.0 0.1 3.9 3 0 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 PRP74652.1 - 0.00069 20.0 0.2 0.27 11.6 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.23 PRP74652.1 - 0.31 11.2 1.7 18 5.5 0.1 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ADH_zinc_N PF00107.26 PRP74654.1 - 2.6e-16 59.8 0.1 7e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pectate_lyase_3 PF12708.7 PRP74654.1 - 6e-10 39.3 3.1 6e-10 39.3 3.1 2.7 1 1 1 2 2 2 1 Pectate lyase superfamily protein ADH_N PF08240.12 PRP74654.1 - 1.4e-07 31.3 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Beta_helix PF13229.6 PRP74654.1 - 4.9e-05 23.2 17.7 0.065 13.1 17.7 3.0 1 1 0 1 1 1 1 Right handed beta helix region ADH_zinc_N_2 PF13602.6 PRP74654.1 - 0.00056 21.0 0.0 0.0013 19.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PLAC8 PF04749.17 PRP74655.1 - 6.9e-18 65.5 12.9 1.1e-17 64.9 12.9 1.3 1 0 0 1 1 1 1 PLAC8 family TrbE PF11100.8 PRP74656.1 - 0.43 10.8 4.4 0.44 10.8 0.3 2.3 2 0 0 2 2 2 0 Conjugal transfer protein TrbE CoA_binding_3 PF13727.6 PRP74656.1 - 2.6 8.0 5.1 2.1 8.3 1.2 2.1 1 1 1 2 2 2 0 CoA-binding domain Homeodomain PF00046.29 PRP74660.1 - 3e-14 52.6 2.4 5.5e-14 51.8 2.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP74660.1 - 0.00015 21.6 1.0 0.00026 20.8 1.0 1.4 1 0 0 1 1 1 1 Homeobox KN domain Methyltransf_31 PF13847.6 PRP74661.1 - 1.3e-17 64.0 0.1 1.9e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP74661.1 - 9.3e-13 48.6 0.0 1.7e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP74661.1 - 9.6e-12 45.5 0.0 1.2e-10 41.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP74661.1 - 1.3e-11 44.6 0.0 3.5e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP74661.1 - 5.3e-06 27.1 0.0 1.3e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP74661.1 - 8.2e-06 25.5 0.0 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PRP74661.1 - 0.00013 21.4 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PrmA PF06325.13 PRP74661.1 - 0.00025 20.5 0.0 0.00057 19.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 PRP74661.1 - 0.0052 16.6 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 PRP74661.1 - 0.0071 15.8 0.0 0.039 13.4 0.0 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB DOT1 PF08123.13 PRP74661.1 - 0.023 14.2 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.12 PRP74661.1 - 0.026 14.1 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 PRP74661.1 - 0.034 14.2 0.1 0.057 13.4 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 PRP74661.1 - 0.047 12.7 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.17 PRP74661.1 - 0.068 12.3 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family HD PF01966.22 PRP74662.1 - 2.2e-07 31.1 0.0 5.3e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 PRP74662.1 - 0.04 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 HDOD domain T_hemolysin PF12261.8 PRP74662.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Thermostable hemolysin GTP_EFTU PF00009.27 PRP74663.1 - 5.1e-34 117.5 0.0 9.8e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PRP74663.1 - 5.2e-16 58.7 0.0 1.4e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 PRP74663.1 - 3.7e-09 36.7 0.1 1.3e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 PRP74663.1 - 0.00031 21.0 0.0 0.00072 19.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PRP74663.1 - 0.0012 18.7 0.6 0.066 13.1 0.0 2.7 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D4 PF14578.6 PRP74663.1 - 0.0023 17.8 0.0 0.0063 16.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.10 PRP74663.1 - 0.0032 16.9 0.0 0.007 15.8 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PRP74663.1 - 0.0044 16.6 0.0 0.012 15.3 0.0 1.7 1 1 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 PRP74663.1 - 0.029 14.7 0.2 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Swi5 PF07061.11 PRP74664.1 - 8.1e-18 64.3 3.2 1.1e-17 63.9 3.2 1.4 1 1 0 1 1 1 1 Swi5 ARD PF03079.14 PRP74665.1 - 5.4e-41 140.4 0.1 6.8e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 PRP74665.1 - 2.8e-08 33.3 0.1 6.3e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 PRP74665.1 - 8.1e-07 29.0 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 PRP74665.1 - 0.0016 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AbiEi_4 PF13338.6 PRP74665.1 - 0.016 15.4 0.0 10 6.4 0.0 2.8 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Cupin_3 PF05899.12 PRP74665.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) ABC2_membrane PF01061.24 PRP74666.1 - 4.1e-82 274.7 56.5 3.4e-43 147.5 17.8 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 PRP74666.1 - 1.1e-46 158.8 0.0 3.3e-23 82.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PRP74666.1 - 2e-07 31.1 0.0 0.061 13.1 0.0 4.2 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PRP74666.1 - 3.7e-06 27.4 0.0 0.0095 16.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 PRP74666.1 - 8e-06 25.5 0.5 0.009 15.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PRP74666.1 - 2.2e-05 24.5 0.4 0.00082 19.3 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 PRP74666.1 - 0.00094 19.7 0.0 0.23 12.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PRP74666.1 - 0.0018 18.3 0.1 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 PRP74666.1 - 0.0058 16.9 0.0 0.14 12.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PRP74666.1 - 0.019 15.2 0.6 0.65 10.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PRP74666.1 - 0.03 13.9 0.1 0.33 10.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain PDR_CDR PF06422.12 PRP74666.1 - 0.073 13.0 0.1 0.073 13.0 0.1 3.6 4 0 0 4 4 3 0 CDR ABC transporter FeoB_N PF02421.18 PRP74666.1 - 0.077 12.5 0.1 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SbcCD_C PF13558.6 PRP74666.1 - 0.081 13.2 0.0 0.83 9.9 0.0 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 PRP74666.1 - 0.17 12.1 0.0 0.51 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain zf-AD PF07776.15 PRP74669.1 - 0.04 14.1 0.2 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Pkinase_Tyr PF07714.17 PRP74673.1 - 1e-56 192.1 0.0 7.3e-38 130.3 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP74673.1 - 2.3e-38 132.1 0.0 6.6e-23 81.4 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Adeno_E3_CR2 PF02439.15 PRP74673.1 - 0.00054 19.7 0.4 0.001 18.7 0.4 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 PRP74673.1 - 0.056 14.3 0.2 0.12 13.2 0.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RhoGEF PF00621.20 PRP74676.1 - 7.2e-45 153.4 2.1 1.2e-44 152.7 2.1 1.4 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.21 PRP74676.1 - 4.1e-19 68.5 9.8 9e-19 67.4 9.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 PRP74676.1 - 6.2e-11 42.7 0.8 6.7e-10 39.4 0.1 2.4 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 PRP74676.1 - 0.00016 21.9 8.5 0.00016 21.9 8.5 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger PH_13 PF16652.5 PRP74676.1 - 0.0072 16.1 0.1 0.3 10.9 0.1 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain Prok-RING_2 PF14445.6 PRP74676.1 - 1.7 8.9 4.4 3.5 7.9 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-C2HC5 PF06221.13 PRP74676.1 - 2.8 8.0 9.3 5.8 7.0 9.3 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-piccolo PF05715.13 PRP74676.1 - 4.7 7.4 8.7 11 6.2 8.7 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger zf-UDP PF14569.6 PRP74676.1 - 5.6 7.1 10.2 3.5 7.8 0.5 2.5 1 1 1 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 PRP74676.1 - 8.1 6.6 9.5 81 3.4 9.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.24 PRP74676.1 - 9.2 6.5 9.8 0.76 10.0 4.9 1.8 2 0 0 2 2 1 0 B-box zinc finger GGACT PF06094.12 PRP74677.1 - 6.5e-08 33.2 0.1 3.6e-06 27.6 0.0 2.2 1 1 1 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like adh_short PF00106.25 PRP74678.1 - 6e-12 45.4 0.0 1.4e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 PRP74678.1 - 4.4e-07 30.0 0.0 8.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 PRP74678.1 - 7.7e-07 28.9 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 PRP74678.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PALP PF00291.25 PRP74678.1 - 0.024 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Methyltransf_15 PF09445.10 PRP74679.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Carb_bind PF10645.9 PRP74680.1 - 6e-09 36.0 27.7 3.4e-08 33.6 15.8 3.1 2 1 1 3 3 3 2 Carbohydrate binding Glyco_hydro_16 PF00722.21 PRP74680.1 - 5.7e-07 29.2 0.1 1.1e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 VWA_2 PF13519.6 PRP74681.1 - 0.0027 18.3 0.7 0.026 15.2 0.1 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PRP74681.1 - 0.043 13.2 0.6 0.12 11.8 0.1 1.9 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VWA PF00092.28 PRP74681.1 - 0.11 12.8 0.1 0.83 9.9 0.0 2.6 2 1 0 2 2 2 0 von Willebrand factor type A domain Chitin_bind_1 PF00187.19 PRP74682.1 - 1.4e-07 31.8 22.6 2.6e-07 31.0 22.6 1.4 1 0 0 1 1 1 1 Chitin recognition protein Aldo_ket_red PF00248.21 PRP74683.1 - 2.3e-44 151.8 0.0 2.9e-44 151.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3511 PF12023.8 PRP74683.1 - 0.076 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) PG_binding_1 PF01471.18 PRP74684.1 - 9.1e-18 64.2 0.0 5.3e-05 23.4 0.0 4.1 4 0 0 4 4 4 3 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 PRP74684.1 - 0.0024 18.1 0.0 0.0065 16.7 0.0 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain PHM7_cyt PF14703.6 PRP74684.1 - 0.04 14.2 3.1 0.12 12.6 3.1 1.8 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter EzrA PF06160.12 PRP74684.1 - 0.045 11.9 10.3 0.1 10.8 10.3 1.5 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Uso1_p115_C PF04871.13 PRP74684.1 - 0.075 13.4 7.8 0.16 12.3 5.6 2.5 1 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 PRP74684.1 - 0.1 12.4 3.2 0.34 10.7 3.2 2.0 1 0 0 1 1 1 0 Septum formation initiator Calici_MSP PF05752.11 PRP74684.1 - 0.11 12.3 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 Calicivirus minor structural protein Striatin PF08232.12 PRP74684.1 - 8.1 7.0 15.9 0.043 14.4 3.3 3.2 4 0 0 4 4 4 0 Striatin family VMA21 PF09446.10 PRP74685.1 - 0.0027 17.8 10.8 0.0036 17.4 10.8 1.2 1 0 0 1 1 1 1 VMA21-like domain Polysacc_synt_3 PF13440.6 PRP74685.1 - 0.0088 15.3 0.4 0.0088 15.3 0.4 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Orf78 PF06024.12 PRP74685.1 - 0.046 14.0 0.1 0.56 10.5 0.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Pkinase_Tyr PF07714.17 PRP74686.1 - 2.7e-73 246.4 0.0 3.9e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74686.1 - 1.9e-54 184.8 0.0 2.7e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP74686.1 - 2.5e-05 23.7 0.0 5.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SKG6 PF08693.10 PRP74686.1 - 7.2e-05 22.1 5.1 0.00016 21.0 5.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 PRP74686.1 - 9.2e-05 21.4 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Chlam_PMP PF02415.17 PRP74686.1 - 0.0028 18.0 2.1 0.04 14.4 0.2 13.1 14 1 0 14 14 13 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Vpu PF00558.19 PRP74686.1 - 0.024 14.4 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Vpu protein CcmD PF04995.14 PRP74686.1 - 0.097 12.8 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Chordopox_A13L PF05961.11 PRP74686.1 - 0.1 12.9 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Adeno_E3_CR2 PF02439.15 PRP74686.1 - 0.13 12.0 3.7 0.31 10.8 3.7 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF4448 PF14610.6 PRP74686.1 - 0.14 11.9 0.1 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Syndecan PF01034.20 PRP74686.1 - 0.39 10.7 1.2 0.86 9.6 1.2 1.5 1 0 0 1 1 1 0 Syndecan domain Pkinase_Tyr PF07714.17 PRP74687.1 - 8e-69 231.8 0.0 2.3e-68 230.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74687.1 - 5.1e-46 157.2 0.0 9.5e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GvpL_GvpF PF06386.11 PRP74687.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Pkinase_fungal PF17667.1 PRP74687.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Herpes_gE PF02480.16 PRP74687.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Haspin_kinase PF12330.8 PRP74687.1 - 0.15 11.0 0.9 4.7 6.0 0.2 2.1 2 0 0 2 2 2 0 Haspin like kinase domain SKG6 PF08693.10 PRP74687.1 - 0.22 11.0 3.1 0.43 10.0 3.1 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MCM PF00493.23 PRP74688.1 - 2.2e-96 321.3 0.2 5.2e-96 320.1 0.2 1.7 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PRP74688.1 - 4.5e-31 107.3 0.6 4.1e-29 101.0 0.6 2.5 1 1 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PRP74688.1 - 6.7e-22 77.7 2.6 7e-22 77.7 1.1 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain SASA PF03629.18 PRP74688.1 - 4e-13 49.5 0.0 7.4e-12 45.4 0.0 2.4 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase MCM6_C PF18263.1 PRP74688.1 - 1.3e-12 47.9 2.1 3e-12 46.7 2.1 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 PRP74688.1 - 2.2e-11 44.2 0.0 6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PRP74688.1 - 7.9e-07 28.7 0.0 1.1e-05 24.9 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PRP74688.1 - 7.5e-06 25.8 0.0 2.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP74688.1 - 0.0015 18.6 0.0 0.0051 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RicinB_lectin_2 PF14200.6 PRP74688.1 - 0.0054 17.4 0.2 0.023 15.4 0.2 2.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Sigma54_activat PF00158.26 PRP74688.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Big_6 PF17936.1 PRP74688.1 - 0.061 13.6 0.6 0.24 11.7 0.6 2.0 1 0 0 1 1 1 0 Bacterial Ig domain Ribosomal_S17 PF00366.20 PRP74689.1 - 1.6e-14 53.8 0.7 2.8e-14 53.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_L39 PF00832.20 PRP74690.1 - 1.5e-10 40.5 1.3 2.1e-10 40.1 1.3 1.2 1 0 0 1 1 1 1 Ribosomal L39 protein 2OG-FeII_Oxy_2 PF13532.6 PRP74692.1 - 0.00099 19.3 0.0 0.35 11.0 0.0 2.2 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily CAMSAP_CC1 PF17095.5 PRP74695.1 - 0.071 13.0 1.5 0.21 11.5 1.2 2.0 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin DUF4385 PF14328.6 PRP74695.1 - 0.09 12.8 4.1 0.18 11.8 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4385) DUF4110 PF13422.6 PRP74696.1 - 0.055 13.5 2.1 0.11 12.5 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) GldM_C PF12080.8 PRP74696.1 - 0.11 12.7 0.1 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 GldM C-terminal domain DUF3405 PF11885.8 PRP74696.1 - 0.21 10.2 2.1 0.27 9.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) I_LWEQ PF01608.17 PRP74696.1 - 0.25 11.6 6.2 3.2 8.0 6.4 2.1 2 0 0 2 2 2 0 I/LWEQ domain PdaC PF13739.6 PRP74696.1 - 0.31 12.0 2.6 0.6 11.1 2.6 1.5 1 0 0 1 1 1 0 Deacetylase PdaC EMC3_TMCO1 PF01956.16 PRP74696.1 - 2.7 7.7 5.8 3.9 7.2 5.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like SAP PF02037.27 PRP74697.1 - 8.3e-05 22.2 0.2 0.00013 21.7 0.2 1.4 1 0 0 1 1 1 1 SAP domain RVT_1 PF00078.27 PRP74698.1 - 1.9e-16 60.3 0.6 1.5e-14 54.0 0.1 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4580 PF15162.6 PRP74698.1 - 0.1 12.2 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4580) DUF3583 PF12126.8 PRP74699.1 - 0.029 13.8 0.2 0.042 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Trypsin PF00089.26 PRP74702.1 - 0.0047 16.8 0.1 0.0067 16.3 0.1 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PRP74702.1 - 0.0052 17.7 0.0 0.0063 17.4 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 PRP74702.1 - 0.0091 15.2 0.1 0.012 14.8 0.1 1.1 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_C3 PF00548.20 PRP74702.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Vinculin PF01044.19 PRP74703.1 - 5.3e-13 48.2 15.3 1.5e-11 43.4 9.7 2.3 1 1 1 2 2 2 2 Vinculin family T3SchapCesA PF11439.8 PRP74703.1 - 0.12 12.6 4.6 0.062 13.4 1.0 2.4 2 1 2 4 4 4 0 Type III secretion system filament chaperone CesA HTH_47 PF16221.5 PRP74703.1 - 0.12 11.9 0.2 0.51 9.9 0.2 2.0 1 0 0 1 1 1 0 winged helix-turn-helix Sugar_tr PF00083.24 PRP74705.1 - 2e-81 274.2 15.6 1.3e-61 208.8 4.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PRP74705.1 - 2.9e-27 95.5 47.3 5.1e-23 81.6 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PRP74705.1 - 0.003 16.9 8.4 0.003 16.9 8.4 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 PRP74705.1 - 0.022 13.2 9.5 0.015 13.8 4.2 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3603 PF12227.8 PRP74705.1 - 0.12 11.6 0.1 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3603) DUF4191 PF13829.6 PRP74705.1 - 3.5 6.9 5.8 0.63 9.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Halogen_Hydrol PF10112.9 PRP74705.1 - 6.5 6.7 5.9 11 6.0 0.1 3.1 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein zf-CCCH_3 PF15663.5 PRP74707.1 - 1.3e-14 54.3 12.4 1.8e-12 47.4 5.1 2.7 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH PF00642.24 PRP74707.1 - 0.0021 17.9 1.0 0.0021 17.9 1.0 3.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PRP74707.1 - 0.0035 17.7 21.4 0.012 16.1 2.0 3.2 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 PRP74707.1 - 0.0073 16.3 2.1 0.0073 16.3 2.1 3.2 3 0 0 3 3 3 1 Zinc finger domain DUF2461 PF09365.10 PRP74707.1 - 0.047 13.6 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) V_ATPase_I PF01496.19 PRP74707.1 - 0.06 11.3 0.3 0.11 10.4 0.3 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF484 PF04340.12 PRP74707.1 - 0.064 12.9 0.1 0.096 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Torus PF16131.5 PRP74707.1 - 0.11 13.2 22.2 0.37 11.5 2.5 4.0 2 1 2 4 4 4 0 Torus domain Myc-LZ PF02344.15 PRP74707.1 - 0.95 9.6 6.7 1.9 8.7 6.7 1.5 1 0 0 1 1 1 0 Myc leucine zipper domain UPF0242 PF06785.11 PRP74707.1 - 2.5 8.2 6.8 0.18 11.9 0.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF2570 PF10828.8 PRP74707.1 - 8.6 6.2 9.8 2.1 8.2 5.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) Stathmin PF00836.19 PRP74707.1 - 9.9 6.1 25.4 2.1 8.3 10.0 3.3 3 1 0 3 3 3 0 Stathmin family TBX PF12598.8 PRP74708.1 - 0.056 14.2 0.4 0.11 13.3 0.4 1.5 1 0 0 1 1 1 0 T-box transcription factor EF-hand_1 PF00036.32 PRP74710.1 - 1.5e-12 46.1 3.8 3.5e-05 23.0 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PRP74710.1 - 2.3e-12 47.2 0.8 2.4e-07 31.1 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP74710.1 - 1.3e-11 43.4 0.4 0.0091 15.9 0.1 4.1 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PRP74710.1 - 2.5e-09 36.8 7.1 8.1e-05 22.4 0.1 4.0 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 PRP74710.1 - 1.8e-05 25.0 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Adenine_glyco PF03352.13 PRP74710.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase FDX-ACB PF03147.14 PRP74710.1 - 0.017 15.5 0.5 0.58 10.6 0.0 2.6 2 1 1 3 3 3 0 Ferredoxin-fold anticodon binding domain EF-hand_5 PF13202.6 PRP74710.1 - 0.16 11.6 7.4 0.41 10.2 0.0 4.0 4 1 0 4 4 4 0 EF hand PHO4 PF01384.20 PRP74711.1 - 3.7e-50 170.9 2.8 4.2e-50 170.7 2.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF742 PF05331.11 PRP74711.1 - 0.0042 16.9 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Tautomerase PF01361.21 PRP74711.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme Myb_DNA-binding PF00249.31 PRP74712.1 - 4.9e-51 170.7 37.1 1.5e-15 57.1 0.3 6.9 6 1 0 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP74712.1 - 5e-46 154.8 17.9 3.5e-14 52.8 0.1 6.5 2 1 4 6 6 6 5 Myb-like DNA-binding domain SLIDE PF09111.10 PRP74712.1 - 0.00021 21.3 22.5 0.047 13.7 0.0 6.5 4 1 4 8 8 8 3 SLIDE Myb_DNA-bind_4 PF13837.6 PRP74712.1 - 0.25 11.7 23.3 0.64 10.4 0.2 6.7 4 1 1 6 6 6 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 PRP74712.1 - 0.39 10.9 11.1 3.1 8.1 0.0 5.4 5 1 2 7 7 7 0 SANT/Myb-like domain of DAMP1 Bestrophin PF01062.21 PRP74712.1 - 0.94 8.8 3.0 1.7 8.0 2.5 1.5 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF3818 PF12825.7 PRP74714.1 - 5.7e-15 55.2 0.3 9.3e-09 34.8 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) Img2 PF05046.14 PRP74715.1 - 1.1e-22 80.1 0.2 1.2e-22 80.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) LIM PF00412.22 PRP74716.1 - 6.6e-07 29.5 0.4 1.1e-06 28.7 0.4 1.3 1 0 0 1 1 1 1 LIM domain Chromo PF00385.24 PRP74720.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Herpes_UL56 PF04534.12 PRP74720.1 - 0.019 14.5 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein adh_short PF00106.25 PRP74722.1 - 2.2e-37 128.4 0.0 6.9e-37 126.8 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP74722.1 - 8.5e-30 104.0 0.0 3e-29 102.2 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP74722.1 - 3.7e-09 36.8 0.5 7e-09 35.9 0.5 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PRP74722.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Colicin_im PF03857.13 PRP74722.1 - 1.6 8.7 7.2 0.11 12.5 1.1 2.0 2 0 0 2 2 2 0 Colicin immunity protein S8_pro-domain PF16470.5 PRP74723.1 - 1.6e-12 48.0 0.0 2.2e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase S8 pro-domain DUF4606 PF15379.6 PRP74723.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) TIG PF01833.24 PRP74724.1 - 4e-06 26.8 0.0 9.3e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain DUF3563 PF12086.8 PRP74724.1 - 0.095 12.4 2.0 0.15 11.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) SET PF00856.28 PRP74725.1 - 1.7e-11 44.8 0.0 3.9e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 PRP74725.1 - 0.0015 19.2 1.0 0.0026 18.4 0.4 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Spore_III_AB PF09548.10 PRP74725.1 - 0.058 13.5 0.3 14 5.8 0.5 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Ras PF00071.22 PRP74726.1 - 1.1e-49 168.2 0.0 1.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP74726.1 - 1.2e-23 83.6 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP74726.1 - 4.3e-07 29.6 0.0 5.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP74726.1 - 0.03 13.8 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP74726.1 - 0.048 13.8 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP74726.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SBDS PF01172.18 PRP74727.1 - 1.1e-24 86.4 0.2 1.2e-24 86.1 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ELP6 PF09807.9 PRP74728.1 - 1.1e-31 110.2 4.1 3.2e-30 105.4 4.1 2.1 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 PRP74728.1 - 0.00013 21.6 0.2 0.00021 20.9 0.2 1.3 1 0 0 1 1 1 1 Elongator subunit Iki1 ATPase PF06745.13 PRP74728.1 - 0.00039 19.9 0.2 0.00067 19.1 0.2 1.3 1 0 0 1 1 1 1 KaiC COE1_DBD PF16422.5 PRP74728.1 - 0.024 14.1 0.4 0.041 13.3 0.3 1.4 1 1 0 1 1 1 0 Transcription factor COE1 DNA-binding domain RRM_1 PF00076.22 PRP74729.1 - 4.5e-12 45.6 0.0 8.8e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ureidogly_lyase PF04115.12 PRP74729.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Ureidoglycolate lyase Methyltransf_28 PF02636.17 PRP74730.1 - 4.9e-67 226.3 0.0 1.5e-66 224.7 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase SSPI PF14098.6 PRP74730.1 - 0.059 13.5 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Small, acid-soluble spore protein I HRI1 PF16815.5 PRP74731.1 - 2.7e-24 86.1 0.0 3.9e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Protein HRI1 RNA_pol_I_A49 PF06870.12 PRP74732.1 - 3.5e-15 55.8 0.6 1.4e-13 50.5 0.6 2.4 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF3253 PF11625.8 PRP74735.1 - 0.028 14.6 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) Y_phosphatase PF00102.27 PRP74739.1 - 9.6e-62 208.6 8.9 6.8e-32 110.9 0.4 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP74739.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PRP74739.1 - 0.0005 19.9 3.2 0.0012 18.7 0.3 3.0 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PRP74739.1 - 0.021 14.9 0.4 0.14 12.3 0.0 2.4 2 1 0 2 2 2 0 Inositol hexakisphosphate DUF3342 PF11822.8 PRP74739.1 - 0.099 12.9 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) SnAC PF14619.6 PRP74740.1 - 0.058 14.0 0.0 0.3 11.7 0.0 2.2 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex DUF3290 PF11694.8 PRP74741.1 - 0.047 13.6 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Chlor_dismutase PF06778.12 PRP74741.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Chlorite dismutase L31 PF09784.9 PRP74741.1 - 0.13 12.7 0.0 20 5.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 SET PF00856.28 PRP74745.1 - 0.00033 21.1 0.0 0.00049 20.5 0.0 1.3 1 1 0 1 1 1 1 SET domain Haem_bd PF14376.6 PRP74745.1 - 0.036 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Haem-binding domain Casc1_N PF15927.5 PRP74750.1 - 0.039 13.7 1.5 0.073 12.8 1.5 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus GST_C PF00043.25 PRP74751.1 - 4.2e-09 36.5 0.0 5.7e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP74751.1 - 2.3e-07 30.9 0.0 5.6e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP74751.1 - 0.00021 21.2 0.0 0.00035 20.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP74751.1 - 0.00045 20.6 0.0 0.00092 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP74751.1 - 0.0014 18.9 0.0 0.0035 17.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PRP74751.1 - 0.002 18.4 0.0 0.0037 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain tRNA_synt_1c_R1 PF04558.15 PRP74752.1 - 5.1e-08 33.1 2.0 1e-07 32.1 0.0 2.5 3 1 0 3 3 3 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF5331 PF17265.2 PRP74752.1 - 0.052 13.3 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5331) Y_phosphatase PF00102.27 PRP74754.1 - 4.1e-72 242.6 1.3 2.6e-36 125.4 0.7 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP74754.1 - 0.00015 21.8 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PRP74754.1 - 0.0013 18.6 0.0 0.004 17.0 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PRP74754.1 - 0.0046 17.1 0.0 0.094 12.8 0.0 2.5 2 0 0 2 2 2 1 Inositol hexakisphosphate Ice_nucleation PF00818.17 PRP74755.1 - 0.12 12.5 0.4 0.24 11.6 0.4 1.4 1 0 0 1 1 1 0 Ice nucleation protein repeat EthD PF07110.11 PRP74757.1 - 1.6e-08 35.6 0.3 0.0053 17.9 0.1 2.2 2 0 0 2 2 2 2 EthD domain MmlI PF09448.10 PRP74757.1 - 0.016 15.7 0.0 0.077 13.4 0.0 2.0 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase TAP42 PF04177.12 PRP74758.1 - 9.8e-73 245.1 16.6 1.2e-72 244.8 16.6 1.1 1 0 0 1 1 1 1 TAP42-like family DUF2497 PF10691.9 PRP74758.1 - 0.011 16.1 0.4 0.27 11.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) RhoGEF PF00621.20 PRP74759.1 - 2.6e-44 151.6 1.7 2.6e-44 151.6 1.7 1.9 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 PRP74759.1 - 8.3e-16 58.1 0.0 5.9e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 PRP74759.1 - 0.023 14.5 0.7 0.058 13.2 0.7 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF4527 PF15030.6 PRP74759.1 - 0.27 10.6 7.2 0.44 9.9 5.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4527) OrfB_IS605 PF01385.19 PRP74759.1 - 0.74 10.1 6.9 0.2 11.9 2.6 2.2 2 0 0 2 2 2 0 Probable transposase RPAP1_N PF08621.10 PRP74759.1 - 1.1 9.1 5.6 7.7 6.4 2.0 3.3 3 0 0 3 3 3 0 RPAP1-like, N-terminal RhoGAP PF00620.27 PRP74760.1 - 5e-38 130.3 3.9 8.9e-38 129.5 0.0 3.0 4 0 0 4 4 4 1 RhoGAP domain Shugoshin_N PF07558.11 PRP74760.1 - 0.0028 17.5 0.9 0.0085 15.9 0.9 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Atx10homo_assoc PF09759.9 PRP74760.1 - 0.076 13.0 0.5 0.076 13.0 0.5 2.8 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain TipAS PF07739.13 PRP74760.1 - 0.71 10.4 0.0 0.71 10.4 0.0 3.0 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain DUF4407 PF14362.6 PRP74760.1 - 1.1 8.6 4.9 7.8 5.7 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 PRP74760.1 - 4.2 7.9 17.1 8.6 6.9 0.3 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region ATP11 PF06644.11 PRP74760.1 - 8.8 6.0 13.2 0.78 9.5 5.0 2.3 2 0 0 2 2 2 0 ATP11 protein FKBP_C PF00254.28 PRP74761.1 - 2.4e-13 50.2 0.0 4.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BTHB PF18410.1 PRP74761.1 - 3.1e-09 36.5 1.2 4.6e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Basic tilted helix bundle domain DUF3886 PF13025.6 PRP74761.1 - 1.7 8.9 11.3 0.93 9.7 6.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) zf-CCCH PF00642.24 PRP74762.1 - 1.1e-07 31.5 15.2 0.00037 20.3 1.8 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PRP74762.1 - 6.9e-05 23.5 16.6 0.0026 18.4 0.1 3.2 3 1 0 3 3 3 2 Torus domain RRM_1 PF00076.22 PRP74762.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 PRP74762.1 - 1.6 8.6 17.2 2.8 7.9 6.7 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Imm_superinfect PF14373.6 PRP74763.1 - 8.9 6.3 7.2 2.9 7.9 0.3 3.0 3 0 0 3 3 3 0 Superinfection immunity protein Peptidase_M24 PF00557.24 PRP74764.1 - 5.3e-41 140.6 0.0 7.5e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 CD99L2 PF12301.8 PRP74764.1 - 0.29 11.4 8.5 0.53 10.6 8.5 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF3586 PF12131.8 PRP74765.1 - 0.3 11.3 0.1 0.3 11.3 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3586) Ank_2 PF12796.7 PRP74766.1 - 4e-41 139.5 0.0 4.3e-09 36.9 0.0 5.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP74766.1 - 6e-15 55.4 1.7 3.3e-05 24.3 0.0 6.8 3 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP74766.1 - 2e-12 46.1 0.9 2.5 9.0 0.0 9.1 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 PRP74766.1 - 9.5e-11 41.7 3.2 0.034 14.5 0.0 7.6 4 1 4 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP74766.1 - 9.5e-08 32.2 10.2 3 8.5 0.0 8.9 10 1 1 11 11 11 1 Ankyrin repeat FCD PF07729.12 PRP74766.1 - 0.063 13.7 4.0 2.9 8.3 0.1 4.1 3 1 2 5 5 5 0 FCD domain RabGAP-TBC PF00566.18 PRP74767.1 - 1e-47 162.5 0.0 1e-47 162.5 0.0 4.9 4 1 0 4 4 4 1 Rab-GTPase-TBC domain GRAM PF02893.20 PRP74767.1 - 4.3e-26 91.0 0.7 1.9e-13 50.3 0.2 2.7 2 0 0 2 2 2 2 GRAM domain CDC27 PF09507.10 PRP74767.1 - 0.12 11.8 48.3 0.23 10.8 48.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.11 PRP74767.1 - 0.22 10.0 34.7 0.35 9.3 34.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4207 PF13904.6 PRP74767.1 - 2.4 7.8 52.3 5.6 6.6 52.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) 6PF2K PF01591.18 PRP74768.1 - 4.9e-73 245.1 0.0 6.4e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 PRP74768.1 - 5.4e-37 127.4 0.0 7.5e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 PRP74768.1 - 3.4e-08 33.8 0.0 6.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP74768.1 - 0.039 13.2 0.1 0.096 11.9 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 PRP74768.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Ank_2 PF12796.7 PRP74769.1 - 5.1e-30 103.9 0.3 5.4e-07 30.1 0.0 6.5 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP74769.1 - 5.5e-20 69.3 3.1 0.12 13.0 0.0 12.0 14 0 0 14 14 14 3 Ankyrin repeat Ank_4 PF13637.6 PRP74769.1 - 2.8e-18 66.0 7.7 0.00059 20.3 0.1 9.1 6 2 3 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP74769.1 - 1.4e-14 54.0 7.9 0.19 12.1 0.0 9.5 5 2 4 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP74769.1 - 2.8e-06 27.5 13.2 2.1 9.0 0.1 10.1 13 0 0 13 13 13 1 Ankyrin repeat SBP_bac_11 PF13531.6 PRP74769.1 - 0.0025 17.6 0.2 0.36 10.5 0.0 3.5 2 2 2 4 4 4 1 Bacterial extracellular solute-binding protein DUF4671 PF15710.5 PRP74769.1 - 0.067 12.0 1.8 12 4.6 0.0 3.3 3 2 0 3 3 3 0 Domain of unknown function (DUF4671) DUF2277 PF10041.9 PRP74769.1 - 1.9 8.9 11.4 18 5.7 0.2 5.4 4 2 3 7 7 7 0 Uncharacterized conserved protein (DUF2277) TAF4 PF05236.14 PRP74770.1 - 1.5e-09 38.0 0.1 2.8e-09 37.1 0.0 1.4 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF3106 PF11304.8 PRP74770.1 - 0.015 15.8 0.2 0.03 14.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DNA_pol3_delta PF06144.13 PRP74770.1 - 0.027 14.2 0.5 0.057 13.2 0.2 1.6 2 0 0 2 2 2 0 DNA polymerase III, delta subunit HJURP_C PF12347.8 PRP74770.1 - 0.069 13.2 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat DUF2866 PF11065.8 PRP74770.1 - 0.16 12.0 1.2 0.42 10.7 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) zf-BED PF02892.15 PRP74771.1 - 0.2 11.7 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 BED zinc finger Isochorismatase PF00857.20 PRP74772.1 - 4.7e-21 75.8 0.0 5.8e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Polysacc_deac_1 PF01522.21 PRP74772.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase BTB_2 PF02214.22 PRP74776.1 - 0.00075 19.8 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PDZ_6 PF17820.1 PRP74776.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Adap_comp_sub PF00928.21 PRP74777.1 - 2.7e-16 59.7 0.0 3.5e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ank_4 PF13637.6 PRP74778.1 - 7e-06 26.5 1.8 3.3 8.4 0.1 5.5 4 3 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP74778.1 - 6.6e-05 23.4 0.0 1.6 9.4 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP74778.1 - 0.0016 18.7 0.4 16 6.5 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Peroxidase_2 PF01328.17 PRP74779.1 - 4e-54 184.0 0.0 7.8e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 Peroxidase, family 2 Ras PF00071.22 PRP74780.1 - 1.9e-21 76.3 0.0 3.6e-17 62.4 0.0 2.6 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PRP74780.1 - 0.00018 21.7 0.1 0.00066 19.9 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PRP74780.1 - 0.00025 21.1 0.0 0.0012 18.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase PH PF00169.29 PRP74780.1 - 0.00031 21.2 0.0 0.001 19.6 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 PRP74780.1 - 0.00071 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain AAA_33 PF13671.6 PRP74780.1 - 0.16 12.1 0.1 1.2 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain F_bP_aldolase PF01116.20 PRP74781.1 - 3.2e-91 305.7 0.0 5.9e-91 304.8 0.0 1.5 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II p25-alpha PF05517.12 PRP74781.1 - 3.6e-40 137.7 22.1 2.3e-14 53.8 0.7 3.9 3 0 0 3 3 3 3 p25-alpha Pkinase PF00069.25 PRP74781.1 - 4.4e-29 101.6 0.0 1.1e-28 100.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74781.1 - 1.9e-17 63.4 0.0 4e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 PRP74781.1 - 2.2e-12 47.3 0.3 2.2e-05 25.1 0.2 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP74781.1 - 1.8e-06 28.2 0.0 1.3 9.4 0.0 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2130 PF09903.9 PRP74781.1 - 0.0072 15.6 14.4 0.049 12.9 1.5 2.3 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2130) APG5 PF04106.12 PRP74781.1 - 0.07 12.7 0.7 0.18 11.3 0.7 1.8 1 0 0 1 1 1 0 Autophagy protein Apg5 FAM184 PF15665.5 PRP74781.1 - 0.14 11.9 18.6 0.29 10.9 18.6 1.4 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B BBS2_Mid PF14783.6 PRP74781.1 - 0.17 11.9 0.1 33 4.6 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF4455 PF14643.6 PRP74781.1 - 0.98 8.0 17.6 0.65 8.6 11.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) DUF3235 PF11574.8 PRP74781.1 - 6.4 7.7 6.9 23 5.9 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) DUF758 PF05527.11 PRP74783.1 - 0.068 13.2 0.2 0.29 11.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF758) DUF5566 PF17721.1 PRP74783.1 - 0.22 11.8 2.2 0.37 11.0 2.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5566) DUF445 PF04286.12 PRP74783.1 - 0.29 10.9 3.3 0.7 9.6 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) B_lectin PF01453.24 PRP74784.1 - 0.0014 19.1 0.9 0.012 16.1 0.2 2.4 2 1 1 3 3 3 2 D-mannose binding lectin B_lectin PF01453.24 PRP74785.1 - 0.0004 20.9 0.0 0.062 13.8 0.0 2.5 2 0 0 2 2 2 2 D-mannose binding lectin Neocarzinostat PF00960.18 PRP74785.1 - 0.02 14.9 0.0 0.67 10.0 0.0 2.6 2 0 0 2 2 2 0 Neocarzinostatin family B_lectin PF01453.24 PRP74787.1 - 2.7e-05 24.6 1.9 0.15 12.6 0.1 3.6 2 2 1 4 4 4 2 D-mannose binding lectin Neocarzinostat PF00960.18 PRP74787.1 - 0.0011 18.9 0.2 2 8.4 0.0 4.1 4 0 0 4 4 4 1 Neocarzinostatin family PAP_assoc PF03828.19 PRP74788.1 - 0.047 13.9 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Cid1 family poly A polymerase CAF1C_H4-bd PF12265.8 PRP74791.1 - 7.4e-17 61.4 0.0 1.9e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 PRP74791.1 - 2.5e-16 59.7 16.5 5e-07 30.3 0.4 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP74791.1 - 1.3e-06 28.6 0.8 0.11 12.7 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 PRP74791.1 - 0.074 13.0 1.7 0.32 10.9 0.1 2.4 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term GNAT_acetyltr_2 PF13718.6 PRP74791.1 - 0.23 10.9 1.3 0.27 10.6 0.1 1.7 2 0 0 2 2 2 0 GNAT acetyltransferase 2 RhoGAP PF00620.27 PRP74792.1 - 4.9e-20 71.9 0.0 2.7e-09 37.0 0.0 2.8 1 1 1 2 2 2 2 RhoGAP domain FCH PF00611.23 PRP74792.1 - 3.9e-12 46.3 0.1 2e-11 44.0 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Acetyltransf_1 PF00583.25 PRP74792.1 - 7.3e-11 42.3 0.0 1.5e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP74792.1 - 1.5e-06 28.1 0.1 3.1e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP74792.1 - 2.8e-06 27.2 0.1 1.2e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 PRP74792.1 - 6.1e-06 26.6 0.1 1.2e-05 25.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cluap1 PF10234.9 PRP74792.1 - 0.0011 18.4 6.7 0.0023 17.4 6.7 1.5 1 0 0 1 1 1 1 Clusterin-associated protein-1 Katanin_con80 PF13925.6 PRP74792.1 - 0.028 14.5 1.5 0.21 11.6 0.2 2.6 3 0 0 3 3 3 0 con80 domain of Katanin Acetyltransf_4 PF13420.7 PRP74792.1 - 0.042 14.0 0.5 0.042 14.0 0.5 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TPR_MLP1_2 PF07926.12 PRP74792.1 - 3.4 7.7 12.8 0.41 10.7 8.2 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pkinase_fungal PF17667.1 PRP74793.1 - 1.2e-06 27.6 0.0 1.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Ank_2 PF12796.7 PRP74795.1 - 1e-50 170.2 6.9 1.9e-11 44.4 0.0 5.5 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP74795.1 - 2.9e-33 113.8 4.2 2.1e-05 25.0 0.1 7.7 2 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP74795.1 - 2.2e-23 82.0 7.5 0.075 13.4 0.0 10.3 3 1 7 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP74795.1 - 2.3e-18 64.4 6.2 1.8 9.4 0.0 11.1 12 0 0 12 12 12 3 Ankyrin repeat Ank PF00023.30 PRP74795.1 - 1.1e-17 63.6 19.4 1.1 9.8 0.0 10.6 11 0 0 11 11 11 6 Ankyrin repeat DUF1030 PF06270.11 PRP74795.1 - 3e-05 23.7 0.1 3.2 7.6 0.0 4.5 5 0 0 5 5 5 2 Protein of unknown function (DUF1030) HEPN_LA2681 PF18733.1 PRP74795.1 - 0.0047 16.3 0.0 4.2 6.6 0.0 3.0 2 1 1 3 3 3 2 LA2681-like HEPN DUF3562 PF12085.8 PRP74795.1 - 0.055 13.1 0.1 19 5.0 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3562) Methyltransf_24 PF13578.6 PRP74795.1 - 0.11 13.5 0.1 48 5.0 0.1 4.3 1 1 0 1 1 1 0 Methyltransferase domain RNA_lig_T4_1 PF09511.10 PRP74796.1 - 0.00029 20.8 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 RNA ligase DsbG_N PF18257.1 PRP74796.1 - 0.02 15.0 0.4 0.085 13.0 0.1 2.1 1 1 1 2 2 2 0 Disulfide isomerase DsbG N-terminal MRP-L20 PF12824.7 PRP74797.1 - 1.1e-06 28.9 0.2 1.6e-06 28.4 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 UPF0240 PF06784.11 PRP74797.1 - 8.2e-05 22.7 1.7 0.00011 22.3 1.7 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0240) Coiled-coil_56 PF09813.9 PRP74798.1 - 0.043 13.9 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 DUF1899 PF08953.11 PRP74799.1 - 2.2e-29 101.1 0.1 4e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 PRP74799.1 - 1.2e-20 73.1 0.1 2.3e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 PRP74799.1 - 6.6e-17 61.6 4.2 0.00058 20.6 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP74799.1 - 1.9e-05 24.8 0.4 0.0099 16.2 0.0 3.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4394 PF14339.6 PRP74799.1 - 0.0033 16.8 0.0 0.0052 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4394) Prefoldin_2 PF01920.20 PRP74799.1 - 0.084 12.8 2.5 0.13 12.2 2.5 1.2 1 0 0 1 1 1 0 Prefoldin subunit CBS PF00571.28 PRP74800.1 - 1.7e-09 38.0 4.4 0.021 15.2 0.0 3.4 3 0 0 3 3 3 3 CBS domain WASH-7_mid PF14744.6 PRP74803.1 - 9.8e-151 501.7 9.8 9.8e-151 501.7 9.8 2.0 2 0 0 2 2 2 1 WASH complex subunit 7 WASH-7_N PF14745.6 PRP74803.1 - 6.4e-137 457.5 13.0 1.3e-136 456.5 13.0 1.5 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_C PF14746.6 PRP74803.1 - 1.2e-58 197.7 1.6 4.7e-58 195.8 1.6 2.1 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal FAM167 PF11652.8 PRP74803.1 - 0.07 13.6 1.2 12 6.4 0.1 3.9 3 0 0 3 3 3 0 FAM167 ACPS PF01648.20 PRP74804.1 - 1.3e-22 80.1 0.0 1.4e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Anp1 PF03452.14 PRP74805.1 - 1.8e-36 125.9 0.0 2.4e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Anp1 SNF2_N PF00176.23 PRP74806.1 - 1.3e-57 195.1 0.5 3.7e-57 193.6 0.1 1.9 2 1 0 2 2 2 1 SNF2 family N-terminal domain DUF3535 PF12054.8 PRP74806.1 - 1.1e-23 84.2 3.1 1.1e-23 84.2 3.1 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) Helicase_C PF00271.31 PRP74806.1 - 2.2e-15 56.9 0.1 1.2e-14 54.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 PRP74806.1 - 1.5e-14 52.8 2.2 2.9 8.4 0.0 9.5 11 0 0 11 11 9 3 HEAT repeat HEAT_EZ PF13513.6 PRP74806.1 - 1.7e-10 41.1 3.2 0.0038 17.7 0.0 6.7 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 PRP74806.1 - 1.1e-08 35.3 3.4 0.12 12.8 0.0 6.8 7 2 0 7 7 7 2 HEAT repeats DEAD PF00270.29 PRP74806.1 - 4.3e-06 26.6 0.1 5.2e-05 23.1 0.0 2.9 4 0 0 4 4 4 1 DEAD/DEAH box helicase Vac14_Fab1_bd PF12755.7 PRP74806.1 - 8.8e-05 23.0 0.1 0.068 13.8 0.0 4.3 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region UME PF08064.13 PRP74806.1 - 0.0037 17.2 1.5 2.8 7.9 0.0 5.3 5 1 0 5 5 5 1 UME (NUC010) domain TAF6_C PF07571.13 PRP74806.1 - 0.0061 16.9 0.0 0.31 11.4 0.0 3.7 3 1 1 4 4 4 1 TAF6 C-terminal HEAT repeat domain UDPG_MGDP_dh_C PF03720.15 PRP74806.1 - 0.25 11.8 1.9 5.5 7.5 0.0 3.2 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Pkinase_Tyr PF07714.17 PRP74807.1 - 3.3e-107 357.6 0.0 2.9e-58 197.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP74807.1 - 8.2e-94 313.8 0.0 1.2e-53 182.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 PRP74807.1 - 3e-13 50.2 0.1 0.00033 21.2 0.0 4.8 3 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP74807.1 - 4e-11 42.9 0.9 0.00031 21.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP74807.1 - 1.7e-10 41.2 0.2 0.069 13.8 0.0 5.9 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP74807.1 - 1.8e-05 24.8 0.6 1.6 9.6 0.0 5.3 6 0 0 6 6 4 1 Ankyrin repeat Ank PF00023.30 PRP74807.1 - 3.9e-05 23.9 1.0 4.2 8.0 0.1 5.4 5 0 0 5 5 5 1 Ankyrin repeat Haspin_kinase PF12330.8 PRP74807.1 - 0.00044 19.3 0.2 0.45 9.4 0.0 2.4 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 PRP74807.1 - 0.016 15.1 0.0 0.074 13.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PRP74807.1 - 0.018 14.1 0.1 0.82 8.7 0.0 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 DEC-1_N PF04625.13 PRP74807.1 - 0.066 12.2 0.2 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DHFR_1 PF00186.19 PRP74808.1 - 3.8e-36 124.2 0.0 5.5e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase ArfGap PF01412.18 PRP74809.1 - 3.5e-33 114.1 0.3 1.7e-32 111.9 0.3 2.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Ank_5 PF13857.6 PRP74809.1 - 4.5e-12 46.0 0.1 2.3e-08 34.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP74809.1 - 1.3e-10 41.7 0.1 2.8e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP74809.1 - 3.6e-10 40.2 0.1 3.4e-06 27.5 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) CarboxypepD_reg PF13620.6 PRP74809.1 - 1.5e-09 37.9 1.6 4.9e-09 36.3 1.6 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PRP74809.1 - 9e-09 35.2 0.7 2.5e-08 33.8 0.7 1.8 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Ank PF00023.30 PRP74809.1 - 3.3e-07 30.5 0.7 2.9e-06 27.5 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 PRP74809.1 - 5.7e-07 29.3 0.1 0.0016 18.7 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat LCD1 PF09798.9 PRP74809.1 - 0.36 9.3 3.7 0.6 8.6 3.7 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein EF-hand_4 PF12763.7 PRP74810.1 - 8.2e-27 93.2 0.1 1.5e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PRP74810.1 - 1e-09 37.2 0.1 0.003 17.0 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PRP74810.1 - 6.8e-09 35.0 0.1 0.0066 16.3 0.2 4.3 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PRP74810.1 - 4.1e-07 30.3 0.2 0.00066 20.1 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP74810.1 - 0.0035 16.8 0.5 0.27 10.8 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PRP74810.1 - 0.23 11.3 1.6 1 9.3 0.1 2.8 2 1 1 3 3 3 0 EF-hand domain pair IBN_N PF03810.19 PRP74811.1 - 7e-10 38.7 8.6 1.2e-07 31.5 1.5 4.7 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.10 PRP74811.1 - 0.00056 18.8 0.2 0.0015 17.4 0.2 1.7 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 PRP74811.1 - 0.0048 17.0 3.3 0.058 13.5 0.7 4.2 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 PRP74811.1 - 0.073 13.4 0.9 3.3 8.2 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat NifQ PF04891.12 PRP74811.1 - 0.12 12.8 0.2 0.42 11.0 0.2 2.0 1 0 0 1 1 1 0 NifQ Reo_P9 PF06043.11 PRP74812.1 - 0.086 12.2 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus P9-like family Robl_LC7 PF03259.17 PRP74813.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain Ammonium_transp PF00909.21 PRP74813.1 - 0.056 12.1 0.1 0.078 11.7 0.1 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family Vps55 PF04133.14 PRP74814.1 - 2.7e-36 124.1 6.8 2.7e-36 124.1 6.8 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting 55 DUF3487 PF11990.8 PRP74814.1 - 1 9.3 8.3 2.6 8.0 2.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) DUF4231 PF14015.6 PRP74814.1 - 1.2 9.7 7.4 1.2 9.7 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Cellulase PF00150.18 PRP74816.1 - 8.4e-20 71.3 5.9 1.1e-19 70.9 5.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RVT_1 PF00078.27 PRP74820.1 - 1.4e-17 64.0 0.1 3.1e-12 46.5 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) KAP_NTPase PF07693.14 PRP74823.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 PRP74823.1 - 0.041 13.1 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin VirE PF05272.11 PRP74823.1 - 0.042 13.6 0.1 1.3 8.7 0.0 2.4 1 1 1 2 2 2 0 Virulence-associated protein E AAA_29 PF13555.6 PRP74823.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 PRP74823.1 - 0.072 13.5 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP74823.1 - 0.14 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Poxvirus_B22R PF04395.12 PRP74824.1 - 0.025 14.1 3.6 0.046 13.2 3.6 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein AAA_22 PF13401.6 PRP74826.1 - 6.5e-06 26.5 0.0 1.4e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP74826.1 - 0.00077 19.9 0.0 0.0024 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain WGG PF10273.9 PRP74826.1 - 0.0071 17.0 0.1 4.9 7.9 0.0 2.3 2 0 0 2 2 2 2 Pre-rRNA-processing protein TSR2 RsgA_GTPase PF03193.16 PRP74826.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 PRP74826.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 PRP74826.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2312 PF10073.9 PRP74827.1 - 0.0014 18.3 0.3 1.1 8.9 0.0 2.8 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2312) CobW_C PF07683.14 PRP74827.1 - 0.0069 16.3 0.0 4.9 7.1 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain BTG PF07742.12 PRP74827.1 - 0.026 14.4 0.0 1.9 8.4 0.0 3.0 4 0 0 4 4 4 0 BTG family DUF4943 PF16301.5 PRP74827.1 - 0.043 13.8 0.0 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4943) Gpi16 PF04113.14 PRP74830.1 - 3.8e-127 425.1 0.0 1.8e-69 234.7 0.0 2.3 1 1 1 2 2 2 2 Gpi16 subunit, GPI transamidase component ArfGap PF01412.18 PRP74831.1 - 7.7e-38 129.2 0.8 9.5e-37 125.7 0.0 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 PRP74831.1 - 1.5e-08 35.1 0.2 4.5e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 PRP74831.1 - 0.0037 17.3 0.1 0.017 15.2 0.0 2.1 2 1 0 2 2 2 1 PH domain RA PF00788.23 PRP74831.1 - 0.12 13.0 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain PH_11 PF15413.6 PRP74831.1 - 0.16 12.4 0.8 2.2 8.7 0.5 2.4 1 1 0 2 2 2 0 Pleckstrin homology domain Glyco_trans_1_4 PF13692.6 PRP74832.1 - 4.1e-10 40.2 0.0 8.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF384 PF04064.13 PRP74832.1 - 0.12 12.2 0.1 0.44 10.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF384) Robl_LC7 PF03259.17 PRP74833.1 - 2.1e-22 78.7 0.1 2.4e-22 78.5 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 PRP74833.1 - 0.00018 21.4 0.1 0.00021 21.1 0.1 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 DUF223 PF02721.14 PRP74833.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF223 WD40 PF00400.32 PRP74834.1 - 2.8e-29 100.7 9.9 4.3e-09 36.9 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP74834.1 - 8.2e-10 38.9 0.1 0.094 13.0 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP74834.1 - 0.00037 19.9 0.0 0.0074 15.6 0.0 2.5 1 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 PRP74834.1 - 0.0027 16.7 0.4 0.37 9.7 0.0 3.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP74834.1 - 0.011 14.4 0.1 1.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_2 PF13360.6 PRP74834.1 - 0.051 13.2 0.3 0.15 11.6 0.3 1.8 1 1 0 1 1 1 0 PQQ-like domain Glyco_transf_22 PF03901.17 PRP74835.1 - 9.2e-104 348.0 39.1 1.1e-103 347.8 39.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PH PF00169.29 PRP74836.1 - 2.5e-15 56.9 0.8 2.4e-06 28.0 0.1 3.0 3 0 0 3 3 3 2 PH domain Patatin PF01734.22 PRP74836.1 - 2.3e-11 44.3 0.0 7.4e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase PH_11 PF15413.6 PRP74836.1 - 0.0018 18.7 10.7 0.017 15.5 1.4 4.1 3 1 0 4 4 4 2 Pleckstrin homology domain PH_13 PF16652.5 PRP74836.1 - 0.0021 17.9 0.1 0.0089 15.8 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 PRP74836.1 - 0.016 15.5 0.2 4.6 7.6 0.0 2.9 2 0 0 2 2 2 0 Pleckstrin homology domain Hemopexin PF00045.19 PRP74837.1 - 0.045 13.7 0.0 0.89 9.6 0.0 2.1 2 0 0 2 2 2 0 Hemopexin MCM PF00493.23 PRP74838.1 - 2.7e-95 317.7 0.0 7.3e-95 316.3 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 PRP74838.1 - 3.6e-31 107.6 0.2 4.7e-30 104.0 0.1 2.5 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 PRP74838.1 - 1.7e-24 86.0 2.6 7.6e-24 84.0 1.8 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 PRP74838.1 - 5e-12 46.3 0.1 1.9e-11 44.5 0.1 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PRP74838.1 - 1.1e-07 31.4 0.0 8.6e-07 28.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PRP74838.1 - 0.00095 19.0 0.0 0.003 17.4 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GAGA_bind PF06217.12 PRP74838.1 - 0.0045 17.3 14.8 0.0082 16.5 14.8 1.5 1 0 0 1 1 1 1 GAGA binding protein-like family Sigma54_activat PF00158.26 PRP74838.1 - 0.006 16.3 0.0 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF648 PF04890.13 PRP74838.1 - 0.037 13.8 2.5 0.072 12.8 2.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF648) AAA PF00004.29 PRP74838.1 - 0.055 13.9 0.2 0.26 11.7 0.0 2.3 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) CDC45 PF02724.14 PRP74838.1 - 0.059 11.7 17.7 0.089 11.1 17.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4604 PF15377.6 PRP74838.1 - 0.52 10.7 29.0 0.77 10.2 27.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 PRP74838.1 - 1.5 8.6 21.8 3 7.6 21.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 PRP74838.1 - 3 7.0 5.1 5.1 6.2 5.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Vma12 PF11712.8 PRP74838.1 - 3.9 7.5 5.4 11 6.1 4.5 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SLC12 PF03522.15 PRP74838.1 - 4.2 6.3 14.7 6.8 5.6 14.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 P2X_receptor PF00864.19 PRP74841.1 - 5.1e-15 55.4 1.7 3.1e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 ATP P2X receptor Rap1_C PF11626.8 PRP74841.1 - 0.15 12.2 0.0 0.49 10.5 0.0 1.8 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EF-hand_1 PF00036.32 PRP74842.1 - 2.3e-18 64.3 0.7 6.4e-09 34.7 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 PRP74842.1 - 1.2e-16 59.1 0.8 9.4e-08 31.4 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 PRP74842.1 - 5.3e-16 58.8 0.2 9.6e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP74842.1 - 2.3e-13 48.9 1.1 2e-05 23.8 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PRP74842.1 - 9.7e-10 38.2 5.0 0.00078 19.2 0.1 4.1 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 PRP74842.1 - 4.5e-06 26.9 0.0 0.067 13.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 PRP74842.1 - 0.047 14.0 0.1 1.6 9.0 0.0 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 PRP74842.1 - 0.062 13.6 0.0 6.4 7.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain GPHH PF16905.5 PRP74842.1 - 0.16 11.7 0.0 0.54 10.1 0.0 1.8 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SRP54 PF00448.22 PRP74843.1 - 3.2e-76 255.4 1.0 5.4e-76 254.6 1.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 PRP74843.1 - 3.6e-32 110.9 12.2 9.1e-31 106.4 4.7 3.5 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 PRP74843.1 - 2.7e-18 65.9 2.7 6.1e-18 64.8 2.7 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 PRP74843.1 - 2.8e-07 30.3 0.2 1.3e-06 28.1 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 PRP74843.1 - 3.8e-06 26.3 0.0 7.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 PRP74843.1 - 2.2e-05 24.7 0.0 4.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 PRP74843.1 - 0.00017 20.6 0.2 0.0071 15.4 0.0 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 PRP74843.1 - 0.0011 18.8 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP74843.1 - 0.0019 18.6 0.0 0.0062 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain CLP1_P PF16575.5 PRP74843.1 - 0.0024 17.7 0.3 1.3 8.8 0.0 2.9 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 PRP74843.1 - 0.0053 16.8 0.1 0.025 14.6 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 PRP74843.1 - 0.016 15.5 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PRP74843.1 - 0.031 14.6 0.0 0.069 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 PRP74843.1 - 0.032 14.0 0.1 0.12 12.1 0.1 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA PF00004.29 PRP74843.1 - 0.032 14.6 0.0 0.19 12.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 PRP74843.1 - 0.038 14.4 0.4 0.11 12.9 0.4 1.8 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 PRP74843.1 - 0.058 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ResIII PF04851.15 PRP74843.1 - 0.12 12.4 0.1 0.79 9.7 0.1 2.1 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit Opiods_neuropep PF01160.18 PRP74843.1 - 0.18 11.9 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide DDE_Tnp_1_3 PF13612.6 PRP74843.1 - 1.8 8.5 4.7 2.4 8.1 2.1 2.5 2 1 0 2 2 2 0 Transposase DDE domain RhoGEF PF00621.20 PRP74845.1 - 3.3e-42 144.8 4.5 3.3e-42 144.8 4.5 2.2 2 1 1 3 3 3 1 RhoGEF domain C2 PF00168.30 PRP74845.1 - 5.3e-15 55.6 0.1 1.3e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 C2 domain DUF4407 PF14362.6 PRP74845.1 - 0.18 11.1 17.5 3.6 6.9 15.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Vfa1 PF08432.10 PRP74845.1 - 2.1 8.6 15.7 5.9 7.2 15.7 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4140 PF13600.6 PRP74845.1 - 4.4 7.8 24.4 0.57 10.7 0.1 3.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 PRP74845.1 - 6.8 6.5 25.5 0.29 10.9 0.1 4.8 4 1 0 4 4 4 0 Septum formation initiator DAAD PF18752.1 PRP74845.1 - 8.3 6.2 8.1 2.9 7.6 5.5 1.5 2 0 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase Kelch_5 PF13854.6 PRP74847.1 - 2.8e-46 154.9 10.1 1.5e-08 34.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PRP74847.1 - 2e-41 139.8 13.0 3.1e-09 36.7 0.1 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PRP74847.1 - 1e-39 134.1 14.8 7.5e-08 32.5 0.0 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP74847.1 - 1.6e-31 107.1 7.2 2.3e-06 27.3 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 PRP74847.1 - 9.8e-28 95.5 12.7 4.7e-07 29.3 0.1 6.5 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 PRP74847.1 - 1.2e-26 92.0 13.1 1.3e-06 28.5 0.1 6.7 5 2 1 6 6 6 5 Kelch motif CSRNP_N PF16019.5 PRP74847.1 - 0.00063 19.7 0.0 0.00063 19.7 0.0 2.1 1 1 1 2 2 2 1 Cysteine/serine-rich nuclear protein N-terminus K-box PF01486.17 PRP74847.1 - 0.0016 18.6 21.3 0.084 13.0 21.3 2.3 1 1 0 1 1 1 1 K-box region TPR_MLP1_2 PF07926.12 PRP74847.1 - 0.067 13.3 14.0 0.14 12.2 14.0 1.6 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HR1 PF02185.16 PRP74847.1 - 0.1 12.7 12.7 0.054 13.6 3.8 3.1 3 1 1 4 4 3 0 Hr1 repeat Fez1 PF06818.15 PRP74847.1 - 0.17 12.3 11.9 0.38 11.2 11.9 1.5 1 0 0 1 1 1 0 Fez1 FAM76 PF16046.5 PRP74847.1 - 0.34 10.2 6.2 0.54 9.6 6.2 1.2 1 0 0 1 1 1 0 FAM76 protein ATP_Ca_trans_C PF12424.8 PRP74847.1 - 0.43 11.1 2.1 0.52 10.8 0.2 2.2 2 0 0 2 2 1 0 Plasma membrane calcium transporter ATPase C terminal DUF641 PF04859.12 PRP74847.1 - 0.53 10.6 11.3 0.34 11.2 6.4 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Prp19 PF08606.11 PRP74847.1 - 0.73 9.9 9.6 0.35 10.9 0.2 3.2 3 0 0 3 3 3 0 Prp19/Pso4-like IFT57 PF10498.9 PRP74847.1 - 0.79 8.6 10.2 1.2 8.0 10.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 PRP74847.1 - 1.1 8.6 7.2 2.7 7.3 7.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 PRP74847.1 - 1.8 9.2 15.9 1.1 9.9 8.8 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APC_N_CC PF16689.5 PRP74847.1 - 3.3 7.8 8.8 0.84 9.7 0.2 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain FlaC_arch PF05377.11 PRP74847.1 - 3.6 8.0 8.7 5.1 7.6 1.7 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 PRP74847.1 - 3.8 6.3 14.7 8 5.2 14.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein HMMR_C PF15908.5 PRP74847.1 - 4.5 7.5 9.1 20 5.4 0.3 2.4 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Beta_helix PF13229.6 PRP74848.1 - 1.9e-07 31.1 20.8 0.005 16.7 7.0 4.4 3 2 1 4 4 4 3 Right handed beta helix region Pkinase_Tyr PF07714.17 PRP74849.1 - 2.9e-76 256.2 0.0 5.5e-76 255.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74849.1 - 2.4e-45 155.0 0.0 5.3e-45 153.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP74849.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 PRP74849.1 - 0.073 12.4 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 PRP74849.1 - 0.098 12.6 0.0 0.71 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family EphA2_TM PF14575.6 PRP74849.1 - 0.21 12.5 0.3 0.49 11.3 0.3 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAD_binding_3 PF01494.19 PRP74850.1 - 3.8e-18 65.9 0.0 4.9e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 PRP74850.1 - 0.00081 19.6 0.1 0.0036 17.5 0.0 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PRP74850.1 - 0.0011 18.3 0.1 0.0015 17.8 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP74850.1 - 0.012 14.8 0.1 0.021 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 PRP74850.1 - 0.018 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 PRP74850.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PRP74850.1 - 0.03 13.6 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Glu_dehyd_C PF16912.5 PRP74850.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 PRP74850.1 - 0.14 12.8 0.2 0.67 10.6 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase YtpI PF14007.6 PRP74851.1 - 0.041 14.0 0.2 0.053 13.6 0.2 1.2 1 0 0 1 1 1 0 YtpI-like protein FHA PF00498.26 PRP74853.1 - 8.9e-17 61.2 0.0 2.2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PRP74853.1 - 1.6e-07 31.5 0.1 6.9e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain TraF_2 PF13729.6 PRP74853.1 - 0.44 9.9 3.2 0.74 9.1 3.2 1.4 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Ank_2 PF12796.7 PRP74854.1 - 5.5e-23 81.4 1.7 2.4e-06 28.0 0.0 4.2 2 2 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP74854.1 - 1.9e-22 79.3 2.7 0.0064 17.0 0.0 7.5 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP74854.1 - 1.1e-13 51.1 2.5 0.36 11.2 0.0 7.9 4 4 4 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP74854.1 - 2.9e-13 49.6 4.9 1.3 9.6 0.0 8.9 9 0 0 9 9 9 2 Ankyrin repeat Ank_3 PF13606.6 PRP74854.1 - 1.1e-09 37.7 0.1 18 6.3 0.0 8.0 10 0 0 10 10 10 1 Ankyrin repeat Endonuc-PvuII PF09225.10 PRP74854.1 - 0.076 12.8 0.0 21 4.8 0.0 3.1 2 1 1 3 3 3 0 Restriction endonuclease PvuII MerR-DNA-bind PF09278.11 PRP74854.1 - 0.16 12.5 0.3 0.71 10.4 0.1 2.2 2 0 0 2 2 2 0 MerR, DNA binding DUF4246 PF14033.6 PRP74855.1 - 1.2e-54 186.2 1.4 8e-41 140.6 0.1 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) DUF3430 PF11912.8 PRP74856.1 - 0.017 15.2 7.7 0.031 14.3 7.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) CDC27 PF09507.10 PRP74857.1 - 0.073 12.5 0.9 0.1 11.9 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2306 PF10067.9 PRP74858.1 - 1.1e-09 38.7 3.4 1.1e-09 38.7 3.4 2.2 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) DUF2140 PF09911.9 PRP74858.1 - 0.048 13.2 0.1 0.088 12.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) NAGidase PF07555.13 PRP74859.1 - 3.1e-29 102.2 0.0 1.2e-28 100.4 0.0 2.0 1 1 0 1 1 1 1 beta-N-acetylglucosaminidase G8 PF10162.9 PRP74859.1 - 3.5e-20 72.3 0.0 8.9e-20 71.0 0.0 1.7 1 0 0 1 1 1 1 G8 domain zf-C2HC5 PF06221.13 PRP74859.1 - 2.5e-10 40.2 8.1 5e-10 39.2 8.1 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Beta_helix PF13229.6 PRP74859.1 - 0.022 14.6 0.2 0.022 14.6 0.2 2.4 2 0 0 2 2 2 0 Right handed beta helix region YecM PF06185.12 PRP74859.1 - 0.034 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 YecM protein Pkinase_Tyr PF07714.17 PRP74860.1 - 5.9e-81 271.6 0.0 8.6e-81 271.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74860.1 - 5.5e-51 173.5 0.0 1.5e-50 172.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PRP74860.1 - 0.0024 17.2 0.0 0.0097 15.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PRP74860.1 - 0.0052 15.8 0.2 0.058 12.3 0.2 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP74860.1 - 0.036 14.0 0.0 0.29 11.0 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 PRP74860.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP74860.1 - 0.11 11.2 0.4 0.2 10.4 0.4 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pentapeptide_4 PF13599.6 PRP74860.1 - 1.7 8.8 6.5 14 5.9 1.5 4.1 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) DUF1713 PF08213.11 PRP74861.1 - 4.8e-06 26.4 17.8 6.6e-06 25.9 17.8 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) GST_N PF02798.20 PRP74862.1 - 1.4e-18 67.0 0.0 2.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP74862.1 - 8.7e-13 48.5 0.0 2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP74862.1 - 5e-10 39.5 0.0 1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP74862.1 - 4.1e-07 30.1 0.0 1.3e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP74862.1 - 1.6e-06 28.2 0.0 5.3e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP74862.1 - 0.0012 18.8 0.1 0.0056 16.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain PAN_4 PF14295.6 PRP74863.1 - 1.2e-08 34.7 5.0 1.2e-08 34.7 5.0 2.5 2 0 0 2 2 2 1 PAN domain Chitin_bind_1 PF00187.19 PRP74863.1 - 1.6e-06 28.4 24.4 1.6e-06 28.4 24.4 2.6 2 0 0 2 2 2 1 Chitin recognition protein NHL PF01436.21 PRP74864.1 - 1.9e-20 71.8 0.1 3.5e-06 26.8 0.4 4.9 4 0 0 4 4 4 4 NHL repeat SGL PF08450.12 PRP74864.1 - 3e-09 36.8 0.1 2.1e-05 24.3 0.0 3.5 2 1 0 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 PRP74864.1 - 0.046 13.9 0.0 0.51 10.6 0.0 2.7 3 0 0 3 3 3 0 Arylesterase Thioredoxin_8 PF13905.6 PRP74864.1 - 0.068 13.5 0.1 0.36 11.2 0.1 2.2 1 1 0 1 1 1 0 Thioredoxin-like DUF745 PF05335.13 PRP74865.1 - 0.00062 19.5 6.2 0.00062 19.5 6.2 8.8 6 2 2 9 9 9 2 Protein of unknown function (DUF745) MCC-bdg_PDZ PF10506.9 PRP74865.1 - 0.0098 15.9 5.4 0.0098 15.9 5.4 8.9 9 1 1 10 10 10 1 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_1 PF00170.21 PRP74865.1 - 0.031 14.4 1.1 0.031 14.4 1.1 12.9 12 2 2 14 14 14 0 bZIP transcription factor EMC3_TMCO1 PF01956.16 PRP74865.1 - 0.76 9.5 0.0 0.76 9.5 0.0 5.6 3 1 4 7 7 7 0 Integral membrane protein EMC3/TMCO1-like L27_N PF09060.10 PRP74865.1 - 0.85 9.7 4.5 95 3.2 0.1 3.7 3 0 0 3 3 3 0 L27_N YojJ PF10372.9 PRP74865.1 - 2.2 8.5 11.5 1.1 9.4 0.1 5.1 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus DUF3800 PF12686.7 PRP74865.1 - 9.8 6.8 13.7 1.8e+04 -6.0 13.7 4.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) PrgH PF09480.10 PRP74866.1 - 0.077 12.3 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) NBP1 PF08537.10 PRP74866.1 - 0.079 12.4 1.8 0.17 11.3 0.6 1.8 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 DUF3717 PF12512.8 PRP74866.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) ADIP PF11559.8 PRP74866.1 - 0.46 10.6 5.3 0.44 10.6 1.5 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Metallophos PF00149.28 PRP74867.1 - 9.1e-08 32.8 0.1 1.4e-06 28.9 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase VirK PF06903.12 PRP74869.1 - 0.08 13.0 0.3 0.088 12.9 0.3 1.0 1 0 0 1 1 1 0 VirK protein CE2_N PF17996.1 PRP74870.1 - 4.5e-09 36.3 0.0 7e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 PRP74870.1 - 2.9e-06 27.8 0.3 4.4e-06 27.2 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family APG9 PF04109.16 PRP74870.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg9 Response_reg PF00072.24 PRP74872.1 - 3e-16 59.6 0.3 5.3e-16 58.8 0.2 1.5 2 0 0 2 2 2 1 Response regulator receiver domain Uso1_p115_head PF04869.14 PRP74872.1 - 0.053 12.7 0.0 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region PCMT PF01135.19 PRP74873.1 - 1.1e-51 175.6 0.0 1.6e-50 171.8 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PRP74873.1 - 3.5e-09 36.6 0.0 3.1e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP74873.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PRP74873.1 - 3.1e-06 27.8 0.0 8.1e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP74873.1 - 9.7e-06 26.1 0.1 0.00014 22.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PRP74873.1 - 4.1e-05 23.6 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP74873.1 - 4.9e-05 22.8 0.0 0.0001 21.7 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PRP74873.1 - 5.7e-05 23.0 0.0 0.0002 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 PRP74873.1 - 0.00035 20.3 0.0 0.00052 19.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.14 PRP74873.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 PRP74873.1 - 0.0029 17.7 0.0 0.0094 16.1 0.0 1.7 1 1 1 2 2 2 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 PRP74873.1 - 0.0047 15.9 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 PRP74873.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fibrillarin PF01269.17 PRP74873.1 - 0.056 12.5 0.0 0.13 11.3 0.0 1.5 1 1 1 2 2 2 0 Fibrillarin Methyltransf_18 PF12847.7 PRP74873.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 PRP74873.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.12 PRP74873.1 - 0.15 12.8 0.0 0.33 11.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 PRP74873.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 PRP74873.1 - 0.19 11.4 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 DNA methylase Abp2 PF09441.10 PRP74874.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 ARS binding protein 2 DUF1295 PF06966.12 PRP74875.1 - 7.2e-09 35.5 0.0 1.9e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 PRP74875.1 - 2.2e-05 24.5 0.2 6.1e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 PRP74875.1 - 0.0011 17.8 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family GAS PF13851.6 PRP74875.1 - 0.14 11.5 41.3 0.2 11.0 21.9 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 PRP74875.1 - 0.18 12.0 33.3 0.13 12.5 17.1 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TMEM215 PF15746.5 PRP74875.1 - 1.5 8.2 11.5 5.9 6.3 0.1 3.3 2 1 1 3 3 3 0 TMEM215 family DUF1664 PF07889.12 PRP74875.1 - 2.6 8.1 21.6 7.4 6.6 5.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 PRP74875.1 - 4.7 6.0 38.8 0.7 8.7 17.1 3.2 2 1 2 4 4 4 0 Spc7 kinetochore protein DNA_pol_A PF00476.20 PRP74876.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase family A YdaS_antitoxin PF15943.5 PRP74876.1 - 0.16 11.8 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DZR PF12773.7 PRP74878.1 - 0.013 15.6 7.3 0.013 15.6 7.3 3.1 2 1 2 4 4 4 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 PRP74878.1 - 0.033 13.9 4.8 0.033 13.9 4.8 2.8 3 0 0 3 3 3 0 zinc-ribbon domain RVT_1 PF00078.27 PRP74879.1 - 9.7e-59 198.6 0.5 2e-24 86.4 0.0 6.6 3 1 1 4 4 4 4 Reverse transcriptase (RNA-dependent DNA polymerase) NS3 PF17530.2 PRP74879.1 - 5.4e-05 22.9 0.2 6.4 6.3 0.0 3.7 3 0 0 3 3 3 3 Non-structural protein NS3 nos_propeller PF18764.1 PRP74879.1 - 0.00065 19.6 0.0 4.6 7.2 0.0 3.8 3 0 0 3 3 3 2 Nitrous oxide reductase propeller repeat Bromodomain PF00439.25 PRP74879.1 - 0.001 19.1 0.6 0.5 10.5 0.0 2.7 2 0 0 2 2 2 2 Bromodomain Latrotoxin_C PF15658.6 PRP74879.1 - 0.012 15.3 2.0 2.8 7.7 0.1 2.8 3 0 0 3 3 3 0 Latrotoxin C-terminal domain TetR_C_19 PF17924.1 PRP74879.1 - 0.024 15.2 6.1 33 5.1 0.1 5.1 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain UBA_4 PF14555.6 PRP74879.1 - 0.028 14.2 0.5 1.6e+02 2.2 0.0 4.3 4 0 0 4 4 4 0 UBA-like domain PaREP1 PF05942.11 PRP74879.1 - 0.03 14.2 1.0 6.4 6.7 0.2 3.1 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family Ribosomal_L29e PF01779.17 PRP74879.1 - 4.9 7.6 10.8 12 6.3 0.7 3.7 3 1 0 3 3 3 0 Ribosomal L29e protein family Sporozoite_P67 PF05642.11 PRP74880.1 - 0.27 9.3 2.2 0.34 9.0 2.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Patatin PF01734.22 PRP74882.1 - 5.4e-08 33.3 1.6 1.7e-07 31.7 1.6 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase EAL PF00563.20 PRP74882.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 EAL domain RicinB_lectin_2 PF14200.6 PRP74883.1 - 1.6e-08 35.1 0.5 1.6e-08 35.1 0.5 2.4 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 PRP74883.1 - 0.00015 22.1 0.3 0.00057 20.1 0.3 2.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Peptidase_M91 PF14891.6 PRP74883.1 - 0.08 13.3 0.0 18 5.6 0.0 2.7 3 0 0 3 3 3 0 Effector protein ParBc PF02195.18 PRP74884.1 - 0.028 14.7 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 ParB-like nuclease domain NnrS PF05940.12 PRP74885.1 - 0.0057 16.1 4.0 0.0072 15.7 4.0 1.1 1 0 0 1 1 1 1 NnrS protein ORMDL PF04061.14 PRP74885.1 - 0.096 12.5 2.6 0.097 12.5 0.5 1.9 1 1 1 2 2 2 0 ORMDL family Thioredoxin_8 PF13905.6 PRP74886.1 - 3.3e-29 101.0 0.0 5.3e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PRP74886.1 - 6.2e-10 39.0 0.1 4.2e-07 29.9 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 PRP74886.1 - 3.4e-08 33.3 0.0 4.5e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PRP74886.1 - 3.6e-07 30.1 0.0 5.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 PRP74886.1 - 7.2e-07 29.6 0.0 1.7e-06 28.4 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 PRP74886.1 - 0.0019 18.4 0.0 0.049 13.9 0.0 2.5 1 1 1 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.6 PRP74886.1 - 0.011 15.5 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin SCO1-SenC PF02630.14 PRP74886.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.4 2 0 0 2 2 2 0 SCO1/SenC Thioredoxin_7 PF13899.6 PRP74886.1 - 0.049 13.8 0.0 0.22 11.7 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like EXS PF03124.14 PRP74887.1 - 1.7e-15 57.2 1.3 1.8e-15 57.1 1.3 1.0 1 0 0 1 1 1 1 EXS family G8 PF10162.9 PRP74888.1 - 3.5e-19 69.1 0.1 8.1e-19 67.9 0.0 1.6 2 0 0 2 2 2 1 G8 domain UPF0047 PF01894.17 PRP74888.1 - 0.092 12.9 0.0 4.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0047 WD40 PF00400.32 PRP74890.1 - 5e-13 49.3 10.7 0.002 18.9 1.0 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP74890.1 - 0.001 19.4 1.2 0.3 11.4 0.1 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PRP74890.1 - 0.022 15.2 6.0 10 6.8 0.0 5.7 6 0 0 6 6 6 0 PQQ-like domain Mod_r PF07200.13 PRP74891.1 - 1.1e-30 106.7 12.1 1.3e-30 106.4 12.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RRM_1 PF00076.22 PRP74892.1 - 6.6e-10 38.7 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 PRP74892.1 - 1.8e-08 35.0 0.0 3.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 PRP74892.1 - 2.6e-07 30.5 2.5 6.2e-07 29.3 2.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_3 PF15663.5 PRP74892.1 - 0.0013 18.9 0.2 0.0036 17.5 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 PRP74892.1 - 0.0018 18.2 1.4 0.0018 18.2 1.4 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PRP74892.1 - 0.0026 17.5 2.5 0.0026 17.5 2.5 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger RRM_occluded PF16842.5 PRP74892.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-CCCH_2 PF14608.6 PRP74892.1 - 0.01 16.2 1.3 0.03 14.8 1.3 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 PRP74892.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 PRP74892.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PRP74892.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif FYVE PF01363.21 PRP74892.1 - 0.41 10.8 5.7 0.11 12.7 2.3 2.0 2 0 0 2 2 2 0 FYVE zinc finger Tam41_Mmp37 PF09139.11 PRP74893.1 - 1.5e-97 327.0 0.9 1.7e-97 326.8 0.9 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial STAT_int PF02865.17 PRP74893.1 - 0.023 15.2 0.9 0.79 10.2 0.0 2.4 2 0 0 2 2 2 0 STAT protein, protein interaction domain Ribosomal_L19 PF01245.20 PRP74894.1 - 0.0018 18.2 0.2 0.0032 17.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 DEAD_2 PF06733.15 PRP74894.1 - 0.049 13.2 3.7 0.038 13.6 2.3 1.4 1 1 0 1 1 1 0 DEAD_2 DUF440 PF04269.12 PRP74894.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF440 B12D PF06522.11 PRP74894.1 - 0.39 10.5 0.1 0.39 10.5 0.1 1.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Rsc14 PF08586.10 PRP74894.1 - 4.6 8.1 5.3 9.6 7.1 1.2 2.3 1 1 1 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Retrotran_gag_2 PF14223.6 PRP74896.1 - 0.047 13.4 0.3 0.3 10.8 0.3 2.2 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type MLVIN_C PF18697.1 PRP74897.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Yippee-Mis18 PF03226.14 PRP74900.1 - 0.0022 18.1 0.0 0.0042 17.3 0.0 1.5 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA_8 PF12780.7 PRP74900.1 - 0.052 12.9 0.1 0.79 9.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 Guanylate_cyc PF00211.20 PRP74902.1 - 1.2e-29 103.2 0.1 2.2e-29 102.4 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF948 PF06103.11 PRP74902.1 - 8.8 6.7 8.5 5.3 7.4 2.9 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) LBP_BPI_CETP_C PF02886.17 PRP74903.1 - 4.4e-31 108.2 0.0 7.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain BTB_2 PF02214.22 PRP74903.1 - 1e-10 41.8 0.0 3.6e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 BTB/POZ domain LBP_BPI_CETP PF01273.25 PRP74903.1 - 7.2e-08 32.2 0.0 1.6e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Imm49 PF15575.6 PRP74903.1 - 0.14 11.9 3.0 0.23 11.2 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 49 PAS_9 PF13426.7 PRP74904.1 - 8.8e-06 25.9 0.0 0.19 12.0 0.0 3.1 2 0 0 2 2 2 2 PAS domain Zn_clus PF00172.18 PRP74904.1 - 0.0011 19.0 12.6 0.0011 19.0 12.6 2.8 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_8 PF13188.7 PRP74904.1 - 0.0055 16.7 0.0 0.63 10.1 0.0 2.5 2 0 0 2 2 2 1 PAS domain zf-piccolo PF05715.13 PRP74907.1 - 0.17 12.0 1.8 0.68 10.1 0.0 2.4 3 0 0 3 3 3 0 Piccolo Zn-finger ODR4-like PF14778.6 PRP74908.1 - 6.8e-57 193.1 0.5 8.9e-57 192.7 0.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like tRNA-synt_2b PF00587.25 PRP74909.1 - 2.1e-36 125.5 0.0 3.7e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PRP74909.1 - 4.2e-11 42.8 0.0 8.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Guanylate_cyc PF00211.20 PRP74911.1 - 5.6e-31 107.6 0.5 1.5e-30 106.2 0.3 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DUF996 PF06195.13 PRP74911.1 - 0.051 13.9 4.0 1.5 9.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF2935 PF11155.8 PRP74911.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) FtsL PF04999.13 PRP74911.1 - 0.15 12.1 4.6 0.9 9.6 0.1 2.5 2 0 0 2 2 2 0 Cell division protein FtsL BSD PF03909.17 PRP74912.1 - 4.2e-11 42.7 2.7 1.4e-10 41.0 0.0 3.0 3 0 0 3 3 3 1 BSD domain YqhG PF11079.8 PRP74912.1 - 0.035 13.1 0.4 0.48 9.3 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein YqhG of unknown function Ndc1_Nup PF09531.10 PRP74912.1 - 10 4.7 11.4 0.33 9.6 4.2 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 PRP74913.1 - 2.9e-10 40.6 0.0 0.094 13.3 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP74913.1 - 2.4e-07 30.5 0.1 23 6.0 0.0 7.3 7 0 0 7 7 7 2 Ankyrin repeat AAA PF00004.29 PRP74914.1 - 1.1e-12 48.5 0.0 1.8e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP74914.1 - 3e-08 34.2 0.2 1.6e-05 25.4 0.1 2.3 1 1 1 2 2 2 2 AAA ATPase domain TniB PF05621.11 PRP74914.1 - 3.6e-05 23.3 0.1 0.0031 17.0 0.1 2.2 1 1 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 PRP74914.1 - 4.3e-05 23.8 0.0 0.00014 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 PRP74914.1 - 0.00069 19.6 0.3 0.18 11.7 0.1 2.2 1 1 1 2 2 2 2 ATPase domain predominantly from Archaea TsaE PF02367.17 PRP74914.1 - 0.0054 16.7 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 PRP74914.1 - 0.015 15.3 0.1 0.037 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 PRP74914.1 - 0.022 14.3 0.0 0.059 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PRP74914.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PRP74914.1 - 0.088 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Ribosomal_S7 PF00177.21 PRP74914.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e AAA_14 PF13173.6 PRP74914.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PRP74914.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 PRP74914.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Pkinase_Tyr PF07714.17 PRP74916.1 - 5.7e-43 147.1 0.1 1.1e-42 146.1 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 PRP74916.1 - 3.2e-33 114.7 0.0 5.9e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.25 PRP74916.1 - 2.4e-32 112.4 0.0 4e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PRP74916.1 - 0.0044 16.0 0.1 0.0074 15.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PRP74916.1 - 0.18 11.4 0.1 0.37 10.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pentapeptide_4 PF13599.6 PRP74916.1 - 2.2 8.5 5.7 9.9 6.4 0.0 4.8 6 0 0 6 6 6 0 Pentapeptide repeats (9 copies) DUF440 PF04269.12 PRP74917.1 - 0.038 14.3 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF440 GFA PF04828.14 PRP74919.1 - 2.3e-22 79.2 0.2 3.1e-22 78.7 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NMD3 PF04981.13 PRP74919.1 - 0.068 12.6 0.2 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 NMD3 family DZR PF12773.7 PRP74919.1 - 0.43 10.6 4.7 2.9 8.0 0.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.6 PRP74919.1 - 0.77 9.7 0.1 0.77 9.7 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal Ank_2 PF12796.7 PRP74921.1 - 1.1e-75 250.3 15.2 1e-16 61.3 0.8 8.5 3 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP74921.1 - 9.1e-72 236.6 16.6 5.9e-12 45.9 0.0 12.5 5 2 8 13 13 13 12 Ankyrin repeats (many copies) Sec7 PF01369.20 PRP74921.1 - 1.9e-66 223.2 3.5 3.2e-66 222.5 3.5 1.4 1 0 0 1 1 1 1 Sec7 domain Ank_5 PF13857.6 PRP74921.1 - 9.5e-55 182.0 21.7 3.9e-10 39.8 0.0 12.2 5 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 PRP74921.1 - 1.9e-54 179.9 28.1 5.8e-05 23.3 0.1 15.4 16 0 0 16 16 16 11 Ankyrin repeat Ank_3 PF13606.6 PRP74921.1 - 9.1e-45 145.5 17.5 0.01 16.3 0.0 15.3 15 0 0 15 15 15 9 Ankyrin repeat PH PF00169.29 PRP74921.1 - 1.1e-23 83.8 0.2 3.2e-23 82.2 0.2 1.9 1 0 0 1 1 1 1 PH domain Lipase_3 PF01764.25 PRP74921.1 - 4.5e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PH_11 PF15413.6 PRP74921.1 - 9.2e-07 29.2 1.3 4.1e-06 27.2 1.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PRP74921.1 - 0.0019 18.6 0.2 0.0066 16.8 0.1 2.1 2 0 0 2 2 1 1 Pleckstrin homology domain PH_8 PF15409.6 PRP74921.1 - 0.091 13.1 0.0 0.52 10.6 0.0 2.4 1 0 0 1 1 1 0 Pleckstrin homology domain FSA_C PF10479.9 PRP74924.1 - 0.08 11.1 0.1 0.13 10.4 0.1 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3042 PF11240.8 PRP74925.1 - 0.4 10.7 0.0 0.4 10.7 0.0 3.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3042) Zip PF02535.22 PRP74925.1 - 4.6 6.4 9.9 7.3 5.7 9.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter LRR_4 PF12799.7 PRP74925.1 - 5.8 7.5 14.6 6.6 7.3 1.3 5.5 3 1 3 6 6 6 0 Leucine Rich repeats (2 copies) Presenilin PF01080.17 PRP74925.1 - 9 4.9 12.1 13 4.4 12.1 1.2 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 PRP74925.1 - 9.1 5.6 39.3 14 5.0 39.3 1.2 1 0 0 1 1 1 0 SDA1 SDA1 PF05285.12 PRP74926.1 - 1.8 7.9 11.6 2.4 7.5 11.6 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 PRP74926.1 - 5.1 5.3 7.9 6.9 4.8 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-X PF09415.10 PRP74928.1 - 2.8e-17 62.8 0.1 3e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 PRP74928.1 - 2.7e-06 27.5 0.1 3.1e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PfUIS3 PF11567.8 PRP74928.1 - 0.069 13.5 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein TAFII28 PF04719.14 PRP74928.1 - 0.075 13.1 0.0 0.091 12.9 0.0 1.1 1 0 0 1 1 1 0 hTAFII28-like protein conserved region SH2 PF00017.24 PRP74929.1 - 1.2e-07 31.8 0.1 2.6e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 SH2 domain HSP20 PF00011.21 PRP74930.1 - 2.4e-22 79.0 1.6 4e-22 78.3 1.6 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP74930.1 - 3.1e-09 36.2 0.0 4.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 PRP74930.1 - 9.6e-05 22.6 0.3 0.0005 20.3 0.2 2.1 2 0 0 2 2 2 1 BON domain SKA1 PF07160.12 PRP74931.1 - 0.062 13.1 0.0 0.062 13.1 0.0 2.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Dimer_Tnp_hAT PF05699.14 PRP74932.1 - 0.00047 19.9 0.0 0.00086 19.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3510 PF12022.8 PRP74932.1 - 0.062 13.7 0.0 7.8 6.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) Pkinase_Tyr PF07714.17 PRP74933.1 - 1.1e-44 152.6 0.0 3.6e-44 151.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP74933.1 - 1e-36 126.7 0.0 1.9e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP74933.1 - 4.5e-23 80.9 72.8 2.5e-06 27.7 1.6 11.8 4 2 13 17 17 17 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP74933.1 - 2.5e-19 68.8 68.1 1.3e-05 24.9 7.2 8.7 1 1 8 11 11 11 10 Leucine rich repeat Insulin_TMD PF17870.1 PRP74933.1 - 0.0018 18.3 2.0 0.0057 16.7 2.0 1.9 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Kdo PF06293.14 PRP74933.1 - 0.043 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ly49 PF08391.10 PRP74933.1 - 0.14 12.5 0.2 0.87 10.0 0.2 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Adeno_E3_CR2 PF02439.15 PRP74933.1 - 0.39 10.5 8.6 0.18 11.6 5.9 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LRR_1 PF00560.33 PRP74933.1 - 0.8 10.5 55.3 5.4 8.0 0.2 13.2 13 1 0 13 13 11 0 Leucine Rich Repeat CYYR1 PF10873.8 PRP74933.1 - 1.6 9.1 5.0 0.29 11.6 0.2 2.2 3 0 0 3 3 2 0 Cysteine and tyrosine-rich protein 1 LRR_9 PF14580.6 PRP74933.1 - 1.8 8.0 16.5 5.6 6.4 2.8 3.9 2 1 3 5 5 5 0 Leucine-rich repeat DIL PF01843.19 PRP74934.1 - 1.2e-13 51.2 0.0 4.2e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 DIL domain MPS2 PF17060.5 PRP74934.1 - 0.024 13.9 23.9 0.069 12.4 23.9 1.6 1 1 0 1 1 1 0 Monopolar spindle protein 2 FPP PF05911.11 PRP74934.1 - 0.055 11.7 29.3 0.11 10.6 29.3 1.4 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil LCIB_C_CA PF18599.1 PRP74934.1 - 0.44 9.8 7.6 0.077 12.3 0.9 2.4 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Fez1 PF06818.15 PRP74934.1 - 0.75 10.2 32.3 1.2 9.6 31.5 1.7 1 1 0 1 1 1 0 Fez1 Baculo_PEP_C PF04513.12 PRP74934.1 - 1.7 8.7 8.9 0.58 10.2 0.6 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMCO5 PF14992.6 PRP74934.1 - 7.7 6.0 21.3 14 5.2 21.3 1.3 1 0 0 1 1 1 0 TMCO5 family ABC_tran PF00005.27 PRP74936.1 - 2e-26 93.1 0.0 3.5e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP74936.1 - 5.7e-18 65.1 18.8 3.5e-17 62.5 18.8 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP74936.1 - 1.6e-12 47.8 0.1 1.7e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PRP74936.1 - 0.00021 21.7 0.0 0.00043 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane PF01061.24 PRP74936.1 - 0.0017 17.8 28.6 0.036 13.5 20.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter Zeta_toxin PF06414.12 PRP74936.1 - 0.0027 17.0 0.1 0.48 9.7 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 PRP74936.1 - 0.0038 17.2 0.1 0.0072 16.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 PRP74936.1 - 0.011 15.7 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 PRP74936.1 - 0.016 15.7 0.6 0.027 15.0 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP74936.1 - 0.032 14.0 0.2 0.13 12.0 0.2 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 PRP74936.1 - 0.17 11.3 0.1 19 4.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 PRP74937.1 - 8.6e-28 97.6 0.0 1.7e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP74937.1 - 2.8e-23 82.6 29.8 1.2e-22 80.6 29.8 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP74937.1 - 1.9e-07 31.2 0.1 0.0012 18.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 PRP74937.1 - 0.0034 18.0 0.1 0.0099 16.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_29 PF13555.6 PRP74937.1 - 0.064 13.0 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 PRP74937.1 - 0.15 11.5 0.0 17 4.7 0.1 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 PRP74937.1 - 0.18 11.5 0.1 1 9.0 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Integrase_H2C2 PF17921.1 PRP74940.1 - 5.3e-20 71.3 1.5 1.3e-19 70.0 1.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 PRP74940.1 - 2.6e-17 62.4 1.5 1.2e-11 44.3 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 PRP74940.1 - 2.2e-13 50.5 0.1 5.4e-13 49.2 0.1 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.10 PRP74940.1 - 4.4e-07 30.0 0.1 8.9e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 H2C2 zinc finger Mtf2_C PF14061.6 PRP74940.1 - 0.00071 19.7 1.4 0.79 9.9 0.1 2.5 2 0 0 2 2 2 2 Polycomb-like MTF2 factor 2 DUF1918 PF08940.11 PRP74940.1 - 0.042 13.5 0.1 6.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Ferrochelatase PF00762.19 PRP74940.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Ferrochelatase Chromo_shadow PF01393.19 PRP74940.1 - 0.15 12.2 0.2 21 5.3 0.0 2.5 2 0 0 2 2 2 0 Chromo shadow domain Chromo PF00385.24 PRP74941.1 - 7.3e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Prenyltransf PF01255.19 PRP74942.1 - 1.4e-66 224.2 0.0 2.4e-66 223.5 0.0 1.4 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PNP_UDP_1 PF01048.20 PRP74943.1 - 1.9e-21 76.4 0.0 3.1e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily YscK PF06578.12 PRP74943.1 - 0.078 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 YOP proteins translocation protein K (YscK) Paz_1 PF18349.1 PRP74944.1 - 0.00056 19.8 2.6 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 PAZ domain DUF3405 PF11885.8 PRP74944.1 - 0.04 12.5 3.6 0.068 11.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) MPM1 PF17234.2 PRP74944.1 - 0.31 11.3 12.1 0.52 10.5 0.7 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 MRP-S26 PF14943.6 PRP74944.1 - 1 9.2 18.5 0.22 11.4 12.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 HTH_OrfB_IS605 PF12323.8 PRP74944.1 - 5.4 6.6 10.0 0.65 9.5 0.3 3.2 2 1 1 3 3 3 0 Helix-turn-helix domain rve PF00665.26 PRP74945.1 - 7.7e-13 48.7 0.0 3.9e-11 43.2 0.0 2.3 1 1 1 2 2 2 2 Integrase core domain DUF4286 PF14114.6 PRP74946.1 - 0.66 10.5 5.8 1.3 9.5 0.2 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4286) DUF4359 PF14271.6 PRP74947.1 - 0.052 14.3 0.5 0.12 13.2 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4359) FadA PF09403.10 PRP74947.1 - 0.33 11.5 9.7 1.4 9.4 0.1 3.5 2 1 1 3 3 3 0 Adhesion protein FadA DUF5082 PF16888.5 PRP74947.1 - 0.62 10.3 5.5 0.22 11.8 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Occludin_ELL PF07303.13 PRP74947.1 - 0.83 10.4 9.6 6.4 7.6 1.9 2.5 1 1 1 2 2 2 0 Occludin homology domain OmpH PF03938.14 PRP74947.1 - 0.83 10.0 12.4 0.83 10.0 8.9 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 PRP74947.1 - 6.5 6.8 6.5 1.4 9.0 0.2 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_Rpc4 PF05132.14 PRP74948.1 - 0.038 14.4 4.2 0.088 13.2 4.2 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 PRP74948.1 - 0.045 11.9 28.4 0.1 10.7 28.4 1.6 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 PRP74948.1 - 0.06 11.6 25.2 0.1 10.9 25.2 1.3 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 PRP74948.1 - 0.098 12.8 5.9 0.25 11.5 5.9 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIIAH PF12685.7 PRP74948.1 - 0.11 12.3 8.9 0.097 12.5 5.7 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein SDA1 PF05285.12 PRP74948.1 - 0.13 11.7 28.3 0.25 10.8 28.3 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PRP74948.1 - 0.14 10.4 27.2 0.23 9.6 27.2 1.2 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 PRP74948.1 - 0.17 11.9 39.7 0.51 10.3 39.7 1.8 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF913 PF06025.12 PRP74948.1 - 0.27 10.1 2.7 0.74 8.7 2.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) YL1 PF05764.13 PRP74948.1 - 0.38 10.8 26.0 0.96 9.5 26.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 PRP74948.1 - 0.51 10.2 15.8 1.5 8.6 15.8 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region SpoIIP PF07454.11 PRP74948.1 - 0.62 9.5 9.3 1.2 8.5 9.3 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FmiP_Thoc5 PF09766.9 PRP74948.1 - 1.1 8.4 13.8 1.6 8.0 8.8 2.9 3 0 0 3 3 3 0 Fms-interacting protein/Thoc5 XAP5 PF04921.14 PRP74948.1 - 2.3 8.0 14.1 5.2 6.8 14.1 1.5 1 0 0 1 1 1 0 XAP5, circadian clock regulator CobT PF06213.12 PRP74948.1 - 2.9 7.2 26.5 4.8 6.5 26.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 PRP74948.1 - 3 6.2 28.8 5 5.5 28.8 1.2 1 0 0 1 1 1 0 Mpp10 protein GAS PF13851.6 PRP74953.1 - 0.0041 16.5 7.4 0.0041 16.5 7.4 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding T4BSS_DotI_IcmL PF11393.8 PRP74953.1 - 0.21 11.1 0.6 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 Type-IV b secretion system, inner-membrane complex component DUF2228 PF10228.9 PRP74955.1 - 0.0046 16.7 7.0 0.2 11.4 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2228) DUF2299 PF10061.9 PRP74955.1 - 0.2 11.4 1.5 0.36 10.6 1.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) HMG_box_2 PF09011.10 PRP74956.1 - 0.057 14.0 0.1 0.068 13.8 0.1 1.3 1 1 0 1 1 1 0 HMG-box domain PRT_C PF08372.10 PRP74962.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal AMMECR1 PF01871.17 PRP74966.1 - 4e-42 143.6 0.0 5e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 HOOK PF05622.12 PRP74967.1 - 0.00021 19.6 13.9 0.00026 19.3 13.9 1.2 1 0 0 1 1 1 1 HOOK protein FUSC PF04632.12 PRP74967.1 - 0.0003 19.5 1.9 0.00038 19.2 1.9 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family bZIP_1 PF00170.21 PRP74967.1 - 0.017 15.2 1.0 0.017 15.2 1.0 2.9 3 0 0 3 3 3 0 bZIP transcription factor DUF1515 PF07439.11 PRP74967.1 - 0.15 12.1 0.2 0.46 10.5 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF1664 PF07889.12 PRP74967.1 - 0.15 12.1 8.4 0.038 14.0 3.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF728 PF05304.12 PRP74967.1 - 0.18 11.7 0.1 0.33 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Cauli_AT PF03233.13 PRP74967.1 - 0.21 11.5 7.3 0.18 11.7 0.7 2.5 1 1 1 2 2 2 0 Aphid transmission protein Shugoshin_N PF07558.11 PRP74967.1 - 0.28 11.1 4.7 0.2 11.6 1.9 2.3 2 0 0 2 2 1 0 Shugoshin N-terminal coiled-coil region Laminin_II PF06009.12 PRP74967.1 - 0.43 10.6 10.1 0.27 11.2 5.9 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF4559 PF15112.6 PRP74967.1 - 0.5 10.0 10.7 0.13 12.0 5.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Syntaxin_2 PF14523.6 PRP74967.1 - 1 9.7 13.9 0.073 13.4 2.9 3.0 1 1 0 2 2 2 0 Syntaxin-like protein DASH_Dam1 PF08653.10 PRP74967.1 - 1.1 9.1 2.9 31 4.5 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Occludin_ELL PF07303.13 PRP74967.1 - 1.3 9.8 9.7 0.57 10.9 3.8 3.1 2 1 2 4 4 3 0 Occludin homology domain BST2 PF16716.5 PRP74967.1 - 1.4 9.5 14.3 0.067 13.8 2.7 2.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF745 PF05335.13 PRP74967.1 - 2.3 7.9 10.9 4.8 6.9 1.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DegQ PF08181.11 PRP74967.1 - 2.3 8.4 7.1 5.1 7.3 0.3 2.7 3 0 0 3 3 2 0 DegQ (SacQ) family WSD PF15613.6 PRP74967.1 - 6 7.4 8.7 0.93 10.0 3.8 2.4 3 1 0 3 3 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif TMPIT PF07851.13 PRP74967.1 - 7.8 5.6 8.0 3.7 6.7 5.7 1.7 1 1 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.9 PRP74967.1 - 9.9 6.9 9.7 1.6e+02 3.0 9.1 2.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) CENP-K PF11802.8 PRP74968.1 - 0.0025 17.4 9.0 0.0025 17.4 9.0 3.2 1 1 2 3 3 3 1 Centromere-associated protein K YabA PF06156.13 PRP74968.1 - 0.0036 17.9 20.1 0.11 13.1 14.5 3.9 1 1 2 3 3 3 1 Initiation control protein YabA Syntaxin-6_N PF09177.11 PRP74968.1 - 0.0074 16.8 19.7 2.5 8.7 0.0 4.7 1 1 3 4 4 4 2 Syntaxin 6, N-terminal EzrA PF06160.12 PRP74968.1 - 0.0075 14.5 1.2 0.0075 14.5 1.2 2.9 2 2 1 3 3 3 2 Septation ring formation regulator, EzrA Flagellin_N PF00669.20 PRP74968.1 - 0.03 14.4 1.4 0.03 14.4 1.4 3.3 1 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Laminin_II PF06009.12 PRP74968.1 - 0.038 14.0 16.9 1.8 8.6 6.8 3.9 2 2 1 4 4 4 0 Laminin Domain II bZIP_1 PF00170.21 PRP74968.1 - 0.049 13.7 1.7 0.049 13.7 1.7 3.9 5 1 1 6 6 5 0 bZIP transcription factor AAA_13 PF13166.6 PRP74968.1 - 0.07 11.8 23.5 0.041 12.5 18.3 2.0 1 1 1 2 2 2 0 AAA domain DDE_Tnp_IS240 PF13610.6 PRP74968.1 - 0.091 13.0 2.2 0.16 12.1 0.2 2.3 1 1 1 2 2 2 0 DDE domain Spc7 PF08317.11 PRP74968.1 - 0.1 11.5 26.6 0.017 14.0 18.6 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 PRP74968.1 - 0.2 11.7 18.1 1 9.4 1.2 4.0 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) FUSC PF04632.12 PRP74968.1 - 0.82 8.1 13.5 0.11 11.0 0.2 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family CSN7a_helixI PF18392.1 PRP74968.1 - 2.4 8.1 5.5 1.8 8.5 0.2 3.0 1 1 1 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain HAUS-augmin3 PF14932.6 PRP74968.1 - 2.6 7.5 24.6 4.9 6.6 20.7 2.8 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 MitMem_reg PF13012.6 PRP74968.1 - 7.8 7.0 15.8 1e+03 0.1 15.7 3.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function GAS PF13851.6 PRP74968.1 - 8.7 5.6 31.8 0.28 10.5 12.9 3.6 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding adh_short PF00106.25 PRP74969.1 - 2.1e-29 102.4 2.1 9.2e-29 100.3 2.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP74969.1 - 1.4e-17 64.1 0.8 6.1e-17 62.0 0.8 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP74969.1 - 1.5e-07 31.5 0.1 2.4e-07 30.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP74969.1 - 0.00069 19.1 0.1 0.0064 16.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 PRP74969.1 - 0.0039 17.3 0.5 0.0094 16.0 0.3 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PRP74969.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 PRP74969.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 PRP74969.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DEAD PF00270.29 PRP74970.1 - 8.2e-47 159.2 0.0 1.1e-45 155.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP74970.1 - 5e-31 107.3 0.1 1e-30 106.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 PRP74970.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Methyltransf_17 PF12692.7 PRP74970.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase ResIII PF04851.15 PRP74970.1 - 0.13 12.3 0.0 15 5.6 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RNase_H PF00075.24 PRP74971.1 - 0.00043 20.5 0.0 0.00087 19.5 0.0 1.5 2 0 0 2 2 2 1 RNase H CdiI_N PF18228.1 PRP74972.1 - 0.0069 16.2 0.9 0.031 14.1 0.1 2.6 3 0 0 3 3 3 1 CdiI N-terminal domain dCMP_cyt_deam_1 PF00383.23 PRP74973.1 - 0.0001 22.1 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MalM PF07148.12 PRP74973.1 - 0.0017 18.1 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Maltose operon periplasmic protein precursor (MalM) Toxin-deaminase PF14424.6 PRP74973.1 - 0.0026 17.8 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 The BURPS668_1122 family of deaminases ATPase-cat_bd PF12156.8 PRP74973.1 - 0.0033 18.1 0.0 0.0055 17.4 0.0 1.4 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase XOO_2897-deam PF14440.6 PRP74973.1 - 0.0075 16.4 0.0 0.0098 16.0 0.0 1.2 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase SNAD4 PF18750.1 PRP74973.1 - 0.072 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 MafB19-deam PF14437.6 PRP74973.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase TPR_2 PF07719.17 PRP74975.1 - 2.9e-09 36.4 10.3 0.032 14.3 0.6 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP74975.1 - 5.3e-09 36.2 8.1 0.14 12.4 0.5 6.0 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP74975.1 - 1.4e-07 31.2 4.8 0.062 13.5 0.3 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP74975.1 - 3.9e-07 29.6 1.7 0.036 14.1 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP74975.1 - 1.1e-06 28.2 11.7 0.12 12.3 0.6 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP74975.1 - 1.5e-05 25.2 8.7 0.78 10.0 0.1 5.5 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP74975.1 - 4.6e-05 23.9 3.5 0.77 10.3 0.3 4.8 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP74975.1 - 0.00015 22.3 2.1 5.5 8.1 0.1 5.5 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP74975.1 - 0.0015 18.2 3.9 0.85 9.4 0.7 4.5 5 0 0 5 5 5 1 TPR repeat TPR_16 PF13432.6 PRP74975.1 - 0.0056 17.3 0.1 0.51 11.0 0.2 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF5104 PF17117.5 PRP74975.1 - 0.02 15.3 0.1 0.071 13.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) RPN7 PF10602.9 PRP74975.1 - 0.021 14.6 0.0 0.08 12.7 0.0 2.0 1 1 0 1 1 1 0 26S proteasome subunit RPN7 PPR PF01535.20 PRP74975.1 - 0.12 12.7 5.2 54 4.3 0.2 5.5 6 0 0 6 6 5 0 PPR repeat TPR_MalT PF17874.1 PRP74975.1 - 0.19 11.1 1.7 9.4 5.5 0.1 3.4 3 1 1 4 4 4 0 MalT-like TPR region TPR_21 PF09976.9 PRP74975.1 - 0.27 10.9 1.8 5 6.8 1.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain Actin PF00022.19 PRP74976.1 - 2.9e-10 39.3 0.0 3.2e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Actin Actin_micro PF17003.5 PRP74976.1 - 0.00068 18.9 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative actin-like family Hydrolase_4 PF12146.8 PRP74977.1 - 1.2e-08 34.5 0.2 3.2e-08 33.2 0.2 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP74977.1 - 2.6e-08 33.8 0.3 5.8e-08 32.7 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP74977.1 - 1.7e-05 25.5 0.1 2.6e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 PRP74977.1 - 0.0024 17.8 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 PRP74977.1 - 0.0035 17.5 0.2 0.048 13.8 0.2 2.1 1 1 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 PRP74977.1 - 0.049 13.3 0.0 11 5.6 0.0 2.2 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 PRP74977.1 - 0.075 12.7 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 PRP74977.1 - 0.091 12.5 0.2 1.7 8.3 0.1 2.2 1 1 0 2 2 2 0 PGAP1-like protein BAAT_C PF08840.11 PRP74977.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LRR_6 PF13516.6 PRP74978.1 - 2.8e-21 73.7 35.0 0.0036 17.2 0.3 12.6 13 0 0 13 13 13 9 Leucine Rich repeat LRR_4 PF12799.7 PRP74978.1 - 4.5e-13 49.2 29.9 5.1e-05 23.6 0.7 9.4 6 2 4 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP74978.1 - 2.5e-11 42.5 30.9 1.9 9.3 0.1 12.7 12 0 0 12 12 12 4 Leucine Rich Repeat LRR_8 PF13855.6 PRP74978.1 - 6.6e-07 29.0 30.4 0.0016 18.1 0.2 9.1 8 3 0 8 8 8 3 Leucine rich repeat FTHFS PF01268.19 PRP74979.1 - 3.7e-43 147.6 0.1 5e-43 147.1 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RasGEF PF00617.19 PRP74980.1 - 1e-42 146.4 0.3 4.8e-42 144.2 0.0 2.4 2 0 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 PRP74980.1 - 6.2e-38 128.4 34.3 9.2e-14 51.0 4.1 5.9 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PRP74980.1 - 1.3e-25 89.0 20.2 7.3e-08 32.6 2.5 6.8 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 PRP74980.1 - 6.1e-09 35.9 4.0 3.4e-05 23.8 0.1 2.9 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 PRP74980.1 - 0.00084 18.9 9.6 0.0052 16.3 2.1 3.5 2 1 1 3 3 3 1 Leucine-rich repeat RasGEF_N PF00618.20 PRP74980.1 - 0.017 15.4 0.0 0.054 13.7 0.0 1.9 1 0 0 1 1 1 0 RasGEF N-terminal motif LRR_6 PF13516.6 PRP74980.1 - 0.27 11.4 16.1 2.5 8.4 1.1 5.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 PRP74980.1 - 0.4 11.4 20.1 8.7 7.3 0.2 7.6 8 1 0 8 8 8 0 Leucine Rich Repeat ABC2_membrane PF01061.24 PRP74981.1 - 1.5e-79 266.3 57.3 1.2e-41 142.5 20.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 PRP74981.1 - 1.6e-42 145.2 0.0 4.5e-20 72.6 0.0 3.6 3 0 0 3 3 3 2 ABC transporter AAA PF00004.29 PRP74981.1 - 4.8e-42 143.5 1.8 1.2e-38 132.5 0.0 4.1 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) PDR_CDR PF06422.12 PRP74981.1 - 7.7e-27 93.0 7.6 3.5e-23 81.3 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 PRP74981.1 - 9.4e-09 35.8 0.1 3e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 PRP74981.1 - 1.2e-08 35.5 0.1 0.022 15.2 0.0 4.0 3 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 PRP74981.1 - 1.4e-07 31.6 1.1 1.9e-05 24.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP74981.1 - 2.8e-07 30.9 2.0 0.7 10.2 0.0 4.8 3 1 1 4 4 4 2 AAA domain RsgA_GTPase PF03193.16 PRP74981.1 - 4.1e-07 30.1 0.2 0.00019 21.4 0.1 3.2 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 PRP74981.1 - 9.9e-07 28.4 0.5 0.0082 15.9 0.1 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain RuvB_N PF05496.12 PRP74981.1 - 1.4e-06 28.1 0.1 0.00023 21.0 0.0 3.4 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 PRP74981.1 - 1.8e-06 27.6 0.0 4.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_25 PF13481.6 PRP74981.1 - 2.2e-06 27.4 0.6 0.0027 17.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.17 PRP74981.1 - 2.4e-06 27.4 0.0 0.0071 16.1 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.6 PRP74981.1 - 6.2e-06 26.3 0.1 0.00073 19.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PRP74981.1 - 1e-05 25.7 1.2 0.59 10.3 0.0 4.2 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 PRP74981.1 - 1.8e-05 24.1 0.1 0.021 14.1 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 PRP74981.1 - 2.1e-05 25.0 0.0 1.6 9.3 0.0 3.8 3 0 0 3 3 3 2 AAA domain Bac_DnaA PF00308.18 PRP74981.1 - 5.5e-05 23.1 0.2 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_21 PF13304.6 PRP74981.1 - 0.00016 21.6 0.0 0.26 11.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 PRP74981.1 - 0.00031 20.5 0.0 0.7 9.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 PRP74981.1 - 0.0005 20.4 0.1 1.2 9.5 0.0 4.1 4 0 0 4 4 3 1 RNA helicase TniB PF05621.11 PRP74981.1 - 0.00058 19.3 0.1 2.1 7.7 0.0 3.4 2 1 1 3 3 3 1 Bacterial TniB protein AAA_30 PF13604.6 PRP74981.1 - 0.00065 19.5 0.7 2.7 7.7 0.4 3.4 3 0 0 3 3 3 1 AAA domain DUF3600 PF12207.8 PRP74981.1 - 0.0011 19.0 0.1 0.027 14.4 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3600) Rad17 PF03215.15 PRP74981.1 - 0.0013 18.7 0.0 9.8 6.0 0.0 3.4 3 0 0 3 3 3 0 Rad17 P-loop domain MIT PF04212.18 PRP74981.1 - 0.0023 18.0 0.1 0.0057 16.7 0.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TIP49 PF06068.13 PRP74981.1 - 0.0029 16.8 0.0 0.0078 15.5 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 PRP74981.1 - 0.0031 17.6 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 PRP74981.1 - 0.0079 15.7 0.4 0.7 9.4 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_19 PF13245.6 PRP74981.1 - 0.0092 16.3 0.2 1.5 9.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 PRP74981.1 - 0.011 15.8 0.4 8.5 6.5 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase TsaE PF02367.17 PRP74981.1 - 0.011 15.7 0.4 5.7 7.0 0.1 3.0 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 PRP74981.1 - 0.013 15.1 0.5 0.16 11.5 0.0 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 PRP74981.1 - 0.014 15.3 1.3 6.3 6.7 0.3 3.3 3 0 0 3 3 3 0 NACHT domain ATP-synt_ab PF00006.25 PRP74981.1 - 0.027 14.1 0.0 13 5.3 0.1 2.8 2 2 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 PRP74981.1 - 0.035 14.5 0.1 4.9 7.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 PRP74981.1 - 0.066 12.9 0.1 1.6 8.4 0.0 3.2 4 1 0 4 4 4 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 PRP74981.1 - 0.14 11.6 2.2 0.38 10.1 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 PRP74981.1 - 0.15 11.2 1.7 25 4.0 0.0 3.6 4 0 0 4 4 4 0 NB-ARC domain PhoH PF02562.16 PRP74981.1 - 0.26 10.7 0.8 3.3 7.1 0.1 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.6 PRP74981.1 - 0.48 10.7 7.3 1.4 9.1 0.4 3.8 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.6 PRP74981.1 - 2.3 8.7 5.9 1.6 9.1 0.1 3.1 3 0 0 3 3 2 0 AAA domain ABC2_membrane_3 PF12698.7 PRP74981.1 - 7.9 5.5 48.4 0.22 10.6 18.2 3.1 3 1 0 3 3 2 0 ABC-2 family transporter protein Cadherin_C_2 PF16492.5 PRP74982.1 - 0.12 13.1 3.2 0.21 12.3 0.3 2.5 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal MASE2 PF05230.11 PRP74982.1 - 0.2 11.8 2.9 0.36 10.9 0.2 2.7 3 0 0 3 3 3 0 MASE2 domain DUF4149 PF13664.6 PRP74982.1 - 0.27 11.6 6.3 0.098 13.0 2.3 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) MDM31_MDM32 PF08118.11 PRP74982.1 - 0.83 8.2 5.3 0.23 10.1 1.1 1.9 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins FH2 PF02181.23 PRP74983.1 - 1.4e-76 258.0 0.9 1.4e-76 258.0 0.9 2.9 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PRP74983.1 - 2.3e-28 99.2 6.9 2.3e-28 99.2 6.9 3.1 3 1 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP74983.1 - 7.5e-23 81.1 2.1 1.4e-22 80.1 0.5 2.5 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain RRM_occluded PF16842.5 PRP74984.1 - 0.01 15.7 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Mitofilin PF09731.9 PRP74984.1 - 0.038 12.9 37.7 0.056 12.3 37.7 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SF3b1 PF08920.10 PRP74986.1 - 1.2e-35 122.5 18.2 1.6e-34 118.9 4.7 4.0 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 PRP74986.1 - 2.7e-11 42.7 5.3 0.069 13.4 0.1 9.7 9 0 0 9 9 9 1 HEAT repeat HEAT_2 PF13646.6 PRP74986.1 - 1.1e-09 38.5 5.6 0.42 11.0 0.0 8.4 5 3 3 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 PRP74986.1 - 5.5e-08 33.2 0.3 0.79 10.3 0.0 7.1 9 0 0 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 PRP74986.1 - 0.00011 22.2 19.0 0.91 9.6 0.2 7.7 7 3 2 9 9 9 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PRP74986.1 - 0.00076 20.0 2.0 2.4 8.8 0.0 5.2 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 PRP74986.1 - 0.1 12.4 9.4 1.2 8.9 0.1 4.2 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) APC_N_CC PF16689.5 PRP74986.1 - 2 8.5 10.8 4.9 7.3 0.1 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain DUF719 PF05334.13 PRP74987.1 - 0.0056 16.9 0.1 0.0056 16.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF719) GAT PF03127.14 PRP74987.1 - 0.026 14.8 1.5 0.059 13.7 1.5 1.5 1 0 0 1 1 1 0 GAT domain DUF4744 PF15918.5 PRP74987.1 - 0.088 13.7 0.7 0.088 13.7 0.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4744) Pkinase PF00069.25 PRP74988.1 - 7.3e-106 353.3 0.8 2.1e-60 204.3 0.0 4.2 3 2 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74988.1 - 2.3e-60 204.1 0.6 2e-33 115.8 0.0 3.8 3 2 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP74988.1 - 1.1e-17 64.3 0.0 1.9e-07 30.7 0.0 3.1 3 0 0 3 3 3 2 Kinase-like DUF758 PF05527.11 PRP74988.1 - 2.2e-14 53.9 0.4 5.2e-14 52.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF758) Kdo PF06293.14 PRP74988.1 - 1.6e-12 47.2 5.5 8.8e-07 28.5 0.4 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP74988.1 - 5.7e-12 45.6 1.9 1.7e-07 31.1 0.2 2.7 2 1 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 PRP74988.1 - 1.1e-11 44.2 0.3 5.6e-05 22.1 0.0 2.7 3 0 0 3 3 3 2 Fungal protein kinase APH PF01636.23 PRP74988.1 - 1.1e-10 41.8 0.7 0.00024 21.1 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family FTA2 PF13095.6 PRP74988.1 - 3.5e-07 30.1 0.4 0.021 14.4 0.1 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PRP74988.1 - 0.0014 17.7 7.5 0.079 11.9 0.6 2.6 3 0 0 3 3 3 2 Haspin like kinase domain EcKinase PF02958.20 PRP74988.1 - 0.0029 17.0 0.2 1.8 7.8 0.0 3.1 3 0 0 3 3 3 1 Ecdysteroid kinase Seadorna_VP7 PF07387.11 PRP74988.1 - 0.02 14.0 0.1 3.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Seadornavirus VP7 Ribosomal_S20p PF01649.18 PRP74988.1 - 0.062 13.9 6.7 2.4 8.8 1.9 3.5 3 0 0 3 3 3 0 Ribosomal protein S20 Vta1_C PF18097.1 PRP74988.1 - 0.28 10.9 1.2 29 4.5 0.0 2.9 4 0 0 4 4 4 0 Vta1 C-terminal domain Pkinase PF00069.25 PRP74989.1 - 8.4e-61 205.6 0.0 1.1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP74989.1 - 3.7e-35 121.5 0.0 1e-34 120.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP74989.1 - 1.3e-08 34.5 0.0 1.2e-07 31.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PRP74989.1 - 1.1e-05 24.9 1.1 1.6e-05 24.4 1.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP74989.1 - 1.8e-05 23.7 0.0 2.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 PRP74989.1 - 5.9e-05 22.7 0.3 8.7e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PRP74989.1 - 0.00019 21.5 0.1 0.00028 20.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP74989.1 - 0.0092 15.0 1.3 0.02 13.8 1.3 1.6 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 PRP74989.1 - 0.012 15.2 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 PRP74991.1 - 1.1e-09 37.9 0.0 2.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TBCC PF07986.12 PRP74992.1 - 1.2e-32 112.1 0.2 2.1e-32 111.4 0.2 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 PRP74992.1 - 7.5e-14 52.2 7.0 7.5e-14 52.2 7.0 1.8 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain ALMT PF11744.8 PRP74992.1 - 0.024 13.5 5.1 0.031 13.1 5.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ribosomal_L7Ae PF01248.26 PRP74993.1 - 2.3e-18 65.7 0.3 4.5e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TFIIF_alpha PF05793.12 PRP74994.1 - 7.8e-12 44.6 45.7 1.1e-07 30.8 39.5 3.5 2 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPR_2 PF13041.6 PRP74994.1 - 7.1e-10 38.9 2.7 0.0022 18.2 0.1 4.4 5 0 0 5 5 5 3 PPR repeat family SAP PF02037.27 PRP74994.1 - 1.1e-06 28.2 2.1 4.9e-06 26.2 0.6 2.7 2 0 0 2 2 2 1 SAP domain PPR_3 PF13812.6 PRP74994.1 - 0.0013 18.7 0.2 3.4 7.8 0.0 3.4 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 PRP74994.1 - 0.027 14.7 3.0 0.88 10.0 0.5 3.7 3 0 0 3 3 3 0 PPR repeat DUF3368 PF11848.8 PRP74994.1 - 0.12 12.1 0.5 0.56 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) CTX_RstB PF07459.11 PRP74994.1 - 0.14 12.4 0.2 2.8 8.3 0.0 3.0 3 0 0 3 3 3 0 CTX phage RstB protein TFIIA PF03153.13 PRP74994.1 - 0.9 9.5 35.7 0.96 9.4 14.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 PRP74995.1 - 3.5e-16 59.3 3.4 3.2e-15 56.1 0.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP74995.1 - 2.8e-09 36.9 2.1 7e-08 32.3 0.3 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP74995.1 - 2.2e-05 24.5 0.5 4.7e-05 23.4 0.5 1.5 1 0 0 1 1 1 1 KR domain SHOCT PF09851.9 PRP74995.1 - 0.049 13.4 1.0 0.049 13.4 1.0 1.8 2 0 0 2 2 2 0 Short C-terminal domain NAD_binding_10 PF13460.6 PRP74995.1 - 0.073 13.0 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding EGF_2 PF07974.13 PRP74997.1 - 3.1e-05 24.2 9.3 3.1e-05 24.2 9.3 4.2 4 1 1 5 5 5 3 EGF-like domain PKcGMP_CC PF16808.5 PRP74998.1 - 0.00094 19.0 2.6 0.00094 19.0 2.6 2.5 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase THOC7 PF05615.13 PRP74998.1 - 0.0083 16.4 0.4 0.0083 16.4 0.4 3.3 4 0 0 4 4 4 1 Tho complex subunit 7 WH2 PF02205.20 PRP74998.1 - 0.017 14.9 0.1 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 WH2 motif DUF724 PF05266.14 PRP74998.1 - 0.019 14.8 4.0 0.019 14.8 4.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF724) XkdW PF09636.10 PRP74998.1 - 0.41 10.8 3.2 0.58 10.3 1.3 2.3 2 0 0 2 2 2 0 XkdW protein GP41 PF00517.17 PRP74998.1 - 5.9 6.7 8.8 0.16 11.8 0.4 2.5 2 1 1 3 3 3 0 Retroviral envelope protein ZYG-11_interact PF05884.12 PRP74998.1 - 6.2 6.1 6.1 0.8 9.1 0.4 2.0 2 0 0 2 2 2 0 Interactor of ZYG-11 DUF4407 PF14362.6 PRP74998.1 - 8.7 5.6 14.9 0.2 11.0 7.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF702 PF05142.12 PRP74998.1 - 9.5 6.7 0.0 9.5 6.7 0.0 3.7 2 1 0 3 3 3 0 Domain of unknown function (DUF702) E1_dh PF00676.20 PRP74999.1 - 1.9e-103 345.5 0.1 2.3e-103 345.3 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 PRP74999.1 - 1.8e-05 24.6 2.2 3.9e-05 23.5 2.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 PRP74999.1 - 0.0002 20.7 0.3 0.00034 19.9 0.1 1.5 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase AHH PF14412.6 PRP75000.1 - 0.022 14.8 1.0 0.14 12.2 1.0 2.5 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH ABC2_membrane PF01061.24 PRP75001.1 - 2.9e-85 285.0 56.2 1.4e-47 161.8 20.1 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 PRP75001.1 - 1.1e-32 113.4 0.0 6.2e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 PRP75001.1 - 8.4e-25 86.5 10.8 8e-19 67.3 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 PRP75001.1 - 2.9e-13 49.6 41.6 7.3e-07 28.6 17.8 3.2 2 1 1 3 3 3 2 ABC-2 family transporter protein Zeta_toxin PF06414.12 PRP75001.1 - 8.7e-06 25.2 0.3 0.068 12.5 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 PRP75001.1 - 1.4e-05 25.0 0.0 0.00025 21.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 PRP75001.1 - 8.2e-05 23.2 0.0 0.00018 22.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 PRP75001.1 - 0.00032 20.4 0.1 0.0058 16.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP75001.1 - 0.0012 19.2 0.0 0.38 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 PRP75001.1 - 0.0043 16.6 0.3 0.01 15.4 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 PRP75001.1 - 0.0051 16.7 0.0 0.73 9.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PRP75001.1 - 0.013 15.8 0.1 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PRP75001.1 - 0.03 14.5 0.1 0.69 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PRP75001.1 - 0.057 13.7 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PRP75001.1 - 0.086 12.5 0.1 1.6 8.4 0.4 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PRP75001.1 - 0.087 13.3 0.9 12 6.3 0.0 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 PRP75001.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 PRP75003.1 - 1.1e-55 187.9 0.2 4.8e-28 98.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 PRP75003.1 - 6.3e-55 186.7 19.6 3.8e-37 128.5 2.3 4.3 5 0 0 5 5 4 2 ABC transporter transmembrane region SMC_N PF02463.19 PRP75003.1 - 3.6e-11 42.9 0.0 0.00024 20.6 0.0 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PRP75003.1 - 2.2e-06 27.7 0.6 0.1 12.7 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 PRP75003.1 - 0.00013 21.6 0.9 0.3 10.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PRP75003.1 - 0.00019 21.4 0.3 0.14 12.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 PRP75003.1 - 0.001 18.0 1.1 0.61 8.8 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 PRP75003.1 - 0.0014 18.5 0.5 1.5 8.5 0.1 3.6 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 PRP75003.1 - 0.0032 17.5 6.0 0.12 12.4 0.1 3.4 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 PRP75003.1 - 0.0046 17.4 0.0 3.5 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 PRP75003.1 - 0.0072 16.1 0.1 0.047 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP75003.1 - 0.012 15.9 0.6 7.9 6.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP75003.1 - 0.024 14.3 0.2 10 5.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PRP75003.1 - 0.035 13.4 0.2 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 PRP75003.1 - 0.04 13.6 0.0 0.62 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 PRP75003.1 - 0.11 12.7 1.1 12 6.1 0.1 3.4 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 PRP75003.1 - 0.11 12.0 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PRP75003.1 - 0.12 12.9 12.6 18 5.8 10.1 3.2 2 1 0 2 2 2 0 AAA domain Macoilin PF09726.9 PRP75003.1 - 0.13 10.8 4.6 0.2 10.2 4.6 1.1 1 0 0 1 1 1 0 Macoilin family cobW PF02492.19 PRP75003.1 - 0.19 11.3 4.0 0.77 9.3 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.7 PRP75003.1 - 1.5 7.6 4.8 7.9 5.3 0.0 2.6 3 0 0 3 3 2 0 AAA-like domain DUF87 PF01935.17 PRP75003.1 - 1.9 8.5 8.9 0.51 10.4 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Ku_PK_bind PF08785.11 PRP75004.1 - 0.0061 16.7 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Ku C terminal domain like IBR PF01485.21 PRP75005.1 - 8.7e-22 77.1 43.1 6.2e-13 48.8 6.2 4.9 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 PRP75005.1 - 8.2e-06 25.6 2.8 8.2e-06 25.6 2.8 4.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP75005.1 - 0.0002 21.6 4.7 0.0002 21.6 4.7 5.1 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 PRP75005.1 - 0.00084 19.2 3.1 0.00084 19.2 3.1 4.8 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP75005.1 - 0.0014 18.6 4.8 0.0014 18.6 4.8 4.1 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP75005.1 - 0.0019 18.0 7.1 0.0019 18.0 7.1 5.1 5 0 0 5 5 5 3 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 PRP75005.1 - 0.0053 17.2 1.8 0.11 12.9 2.3 2.8 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 PRP75005.1 - 0.0097 15.9 5.8 0.0097 15.9 5.8 4.3 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 PRP75005.1 - 0.057 13.2 2.3 0.21 11.4 2.3 2.0 1 0 0 1 1 1 0 RING-like zinc finger SH3_1 PF00018.28 PRP75006.1 - 4.5e-17 61.4 0.8 3.3e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 PRP75006.1 - 2.2e-16 59.5 0.6 6.8e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain DUF1192 PF06698.11 PRP75006.1 - 0.18 11.9 1.7 0.32 11.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Septin PF00735.18 PRP75008.1 - 1.8e-22 79.9 0.2 3e-21 76.0 0.2 2.3 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 PRP75008.1 - 0.00011 22.2 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP75008.1 - 0.0033 17.0 0.4 0.026 14.1 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP75008.1 - 0.0052 16.7 0.1 0.45 10.4 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Glyco_transf_88 PF16849.5 PRP75008.1 - 0.042 12.8 0.0 0.098 11.6 0.0 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 88 PIG-P PF08510.12 PRP75008.1 - 0.048 13.6 0.4 0.35 10.8 0.1 2.2 2 0 0 2 2 2 0 PIG-P Porphobil_deam PF01379.20 PRP75009.1 - 1.2e-77 260.0 0.2 1.6e-77 259.6 0.2 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 PRP75009.1 - 1.4e-19 70.2 0.0 2.6e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain MFS_1 PF07690.16 PRP75011.1 - 1.4e-27 96.6 37.5 1.7e-27 96.3 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PRP75011.1 - 1.2e-07 30.6 14.0 1.2e-07 30.6 14.0 2.4 1 1 1 2 2 2 1 MFS/sugar transport protein TMEM174 PF15029.6 PRP75011.1 - 3.7 7.2 5.2 4.7 6.9 0.7 2.3 2 0 0 2 2 2 0 Transmembrane protein 174 AAA PF00004.29 PRP75012.1 - 1.6e-49 167.7 0.1 4.3e-26 91.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP75012.1 - 1.7e-07 31.6 2.1 0.076 13.3 0.0 4.7 5 1 1 6 6 3 2 AAA domain RuvB_N PF05496.12 PRP75012.1 - 2e-07 30.9 0.0 0.028 14.2 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PRP75012.1 - 1.5e-05 25.0 0.0 0.25 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP75012.1 - 1.6e-05 25.4 0.0 0.27 11.6 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain Zot PF05707.12 PRP75012.1 - 2.1e-05 24.3 0.6 0.24 11.0 0.1 3.4 2 2 0 3 3 3 2 Zonular occludens toxin (Zot) AAA_7 PF12775.7 PRP75012.1 - 6.4e-05 22.5 0.1 0.067 12.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 PRP75012.1 - 0.00012 21.9 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 PRP75012.1 - 0.00016 21.4 0.4 0.62 9.8 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain RNA_helicase PF00910.22 PRP75012.1 - 0.00017 21.9 0.0 0.27 11.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 PRP75012.1 - 0.00019 21.5 0.0 0.16 12.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 PRP75012.1 - 0.00027 21.5 0.0 0.75 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 PRP75012.1 - 0.00046 19.6 0.3 1.5 8.2 0.1 3.0 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 PRP75012.1 - 0.00066 18.9 0.0 0.28 10.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) T2SSE PF00437.20 PRP75012.1 - 0.0014 17.8 0.0 0.71 8.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 PRP75012.1 - 0.0014 18.7 0.2 0.52 10.4 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 PRP75012.1 - 0.0017 18.5 0.1 1.8 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 PRP75012.1 - 0.0018 18.4 0.0 2.1 8.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 PRP75012.1 - 0.0021 17.6 0.1 2.6 7.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 PRP75012.1 - 0.0024 17.0 0.2 0.76 8.8 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 PhoH PF02562.16 PRP75012.1 - 0.0025 17.3 0.3 3.1 7.2 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein TIP49 PF06068.13 PRP75012.1 - 0.0026 17.0 0.1 2 7.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_24 PF13479.6 PRP75012.1 - 0.003 17.3 0.2 3.2 7.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PRP75012.1 - 0.005 17.1 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain EGF_2 PF07974.13 PRP75012.1 - 0.0053 17.1 2.0 0.014 15.7 2.0 1.7 1 0 0 1 1 1 1 EGF-like domain ResIII PF04851.15 PRP75012.1 - 0.0063 16.5 0.1 4.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 PRP75012.1 - 0.0065 15.8 0.3 0.37 10.1 0.0 2.7 2 0 0 2 2 2 1 KaiC TIG PF01833.24 PRP75012.1 - 0.0075 16.3 0.4 0.092 12.8 0.0 2.9 2 0 0 2 2 2 1 IPT/TIG domain DUF3038 PF11237.8 PRP75012.1 - 0.019 15.0 0.5 0.048 13.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) PEPCK_ATP PF01293.20 PRP75012.1 - 0.027 13.2 0.3 0.23 10.1 0.2 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase Torsin PF06309.11 PRP75012.1 - 0.027 14.6 0.1 0.51 10.5 0.0 2.5 2 0 0 2 2 2 0 Torsin AAA_17 PF13207.6 PRP75012.1 - 0.034 14.6 6.0 0.87 10.0 0.0 4.6 5 2 1 6 6 4 0 AAA domain AAA_30 PF13604.6 PRP75012.1 - 0.034 13.8 0.3 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PRP75012.1 - 0.051 14.1 0.5 2.4 8.7 0.0 3.7 4 1 0 4 4 4 0 ABC transporter AAA_lid_3 PF17862.1 PRP75012.1 - 0.054 13.3 0.4 3.2 7.6 0.1 2.8 2 0 0 2 2 2 0 AAA+ lid domain ATP-synt_ab PF00006.25 PRP75012.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PPV_E1_C PF00519.17 PRP75012.1 - 0.076 11.8 0.1 0.26 10.1 0.0 1.7 2 0 0 2 2 2 0 Papillomavirus helicase IPT PF01745.16 PRP75012.1 - 0.08 12.3 1.2 9.6 5.5 0.0 2.9 3 0 0 3 3 2 0 Isopentenyl transferase AAA_19 PF13245.6 PRP75012.1 - 0.11 12.9 0.5 8.3 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PRP75012.1 - 0.16 11.8 0.1 0.93 9.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 PRP75013.1 - 1.4e-50 171.1 0.8 9.7e-27 94.0 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PRP75013.1 - 5.4e-08 32.7 0.0 0.014 15.1 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PRP75013.1 - 1.3e-06 28.7 0.1 0.037 14.3 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.14 PRP75013.1 - 3.7e-06 27.0 0.0 0.13 12.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP75013.1 - 4.2e-06 27.2 0.0 0.15 12.5 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain Zot PF05707.12 PRP75013.1 - 1.5e-05 24.7 1.1 0.28 10.8 0.0 3.9 2 2 1 4 4 4 2 Zonular occludens toxin (Zot) AAA_7 PF12775.7 PRP75013.1 - 1.7e-05 24.4 0.1 0.033 13.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 PRP75013.1 - 2.9e-05 23.9 0.1 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 PRP75013.1 - 4e-05 24.0 0.0 0.16 12.4 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 PRP75013.1 - 7.6e-05 23.3 0.0 0.47 11.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 PRP75013.1 - 0.00014 21.6 1.8 0.013 15.3 0.3 2.7 2 0 0 2 2 2 1 AAA+ lid domain DUF815 PF05673.13 PRP75013.1 - 0.00014 21.1 0.0 0.13 11.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 PRP75013.1 - 0.00024 20.9 0.0 0.31 10.7 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain T2SSE PF00437.20 PRP75013.1 - 0.00029 20.0 0.0 0.41 9.6 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 PRP75013.1 - 0.00037 20.1 0.1 1.3 8.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 PRP75013.1 - 0.0004 20.6 0.1 1.4 9.0 0.1 3.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 PRP75013.1 - 0.00041 19.8 1.6 0.77 9.1 0.1 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 PRP75013.1 - 0.00062 19.1 0.1 1 8.5 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Parvo_NS1 PF01057.17 PRP75013.1 - 0.00066 18.9 0.1 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 PRP75013.1 - 0.00068 19.1 0.3 1.6 8.2 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 PRP75013.1 - 0.00069 19.4 0.2 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.6 PRP75013.1 - 0.00073 19.7 0.0 0.45 10.6 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 PRP75013.1 - 0.00091 19.5 0.0 0.78 10.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 PRP75013.1 - 0.00098 19.2 0.1 1.6 8.7 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ATPase PF06745.13 PRP75013.1 - 0.0016 17.8 0.2 0.18 11.1 0.0 2.8 2 0 0 2 2 2 1 KaiC AAA_33 PF13671.6 PRP75013.1 - 0.0018 18.5 2.6 0.9 9.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 PRP75013.1 - 0.0058 17.1 3.5 0.52 10.7 0.0 3.9 3 2 1 4 4 3 1 AAA domain Torsin PF06309.11 PRP75013.1 - 0.0071 16.4 0.1 0.25 11.4 0.0 2.6 2 0 0 2 2 2 1 Torsin PEPCK_ATP PF01293.20 PRP75013.1 - 0.0076 15.0 0.3 0.11 11.2 0.2 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxykinase IPT PF01745.16 PRP75013.1 - 0.0096 15.3 0.2 5 6.5 0.0 2.9 2 0 0 2 2 2 0 Isopentenyl transferase AAA_30 PF13604.6 PRP75013.1 - 0.0097 15.6 1.5 2.4 7.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain PPV_E1_C PF00519.17 PRP75013.1 - 0.024 13.5 0.1 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 Papillomavirus helicase AAA_19 PF13245.6 PRP75013.1 - 0.03 14.7 0.4 4.3 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 PRP75013.1 - 0.044 13.4 0.0 0.087 12.5 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.27 PRP75013.1 - 0.046 14.2 2.4 1.2 9.7 0.0 3.8 3 1 0 3 3 3 0 ABC transporter AAA_23 PF13476.6 PRP75013.1 - 0.051 14.1 11.3 0.62 10.5 0.1 3.6 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 PRP75013.1 - 0.13 12.1 2.2 0.46 10.4 0.0 2.9 3 0 0 3 3 2 0 RsgA GTPase AAA_29 PF13555.6 PRP75013.1 - 0.16 11.8 0.3 6.9 6.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain NACHT PF05729.12 PRP75013.1 - 0.19 11.6 0.7 7.3 6.5 0.0 3.2 4 0 0 4 4 3 0 NACHT domain AAA_11 PF13086.6 PRP75013.1 - 0.55 10.0 10.0 2 8.2 0.0 3.8 4 0 0 4 4 3 0 AAA domain YceD PF02620.17 PRP75013.1 - 1.1 9.4 5.4 1.2 9.2 3.5 2.0 2 0 0 2 2 1 0 Large ribosomal RNA subunit accumulation protein YceD adh_short PF00106.25 PRP75014.1 - 2.6e-17 62.9 2.8 3.3e-16 59.3 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP75014.1 - 1.6e-09 37.7 2.3 3.8e-08 33.2 0.3 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP75014.1 - 7.6e-06 26.0 0.5 1.5e-05 25.0 0.5 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP75014.1 - 0.023 14.6 0.2 0.034 14.0 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding SHOCT PF09851.9 PRP75014.1 - 0.28 11.0 0.9 0.57 10.0 0.2 1.8 2 0 0 2 2 2 0 Short C-terminal domain Gtr1_RagA PF04670.12 PRP75016.1 - 6e-102 339.9 3.7 7.5e-102 339.6 3.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 PRP75016.1 - 4.1e-09 36.1 0.1 6.4e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PRP75016.1 - 5e-09 36.4 0.0 1.5e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP75016.1 - 6.5e-08 32.3 0.7 9.9e-08 31.7 0.1 1.6 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 PRP75016.1 - 4.5e-07 29.9 0.0 9.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PRP75016.1 - 0.00064 19.2 0.2 0.001 18.5 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PRP75016.1 - 0.039 13.7 0.3 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NUDIX PF00293.28 PRP75017.1 - 6.1e-07 29.5 0.0 9.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain RIO1 PF01163.22 PRP75018.1 - 2.2e-77 258.9 0.4 2.2e-77 258.9 0.4 2.0 2 1 1 3 3 3 1 RIO1 family Pkinase_fungal PF17667.1 PRP75018.1 - 6.5e-05 21.9 0.1 6.5e-05 21.9 0.1 2.4 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 PRP75018.1 - 0.0034 16.8 0.1 0.0034 16.8 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain CCDC106 PF15794.5 PRP75018.1 - 4.9 6.8 25.0 13 5.4 0.2 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 RICTOR_N PF14664.6 PRP75018.1 - 8.9 5.2 6.3 0.52 9.3 0.1 1.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term p450 PF00067.22 PRP75019.1 - 4.4e-87 292.7 0.0 5.4e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HEAT_2 PF13646.6 PRP75020.1 - 0.00022 21.6 0.3 0.00079 19.8 0.1 2.0 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 PRP75020.1 - 0.0052 16.9 2.1 0.14 12.5 0.0 3.6 5 0 0 5 5 5 1 HEAT repeat TPR_12 PF13424.6 PRP75022.1 - 1.2e-35 121.6 17.5 5.4e-12 45.8 0.0 6.9 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 PRP75022.1 - 3e-12 45.6 20.7 0.022 14.9 0.8 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 PRP75022.1 - 1.5e-11 43.6 21.2 0.00084 19.1 0.2 8.1 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP75022.1 - 1.1e-09 37.8 30.7 0.0016 18.5 0.1 8.7 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP75022.1 - 1.8e-09 37.6 12.8 2.3 9.3 0.4 8.9 8 2 2 10 10 9 2 Tetratricopeptide repeat SNAP PF14938.6 PRP75022.1 - 3.3e-09 36.6 26.8 0.013 14.9 0.3 4.3 1 1 4 5 5 5 3 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 PRP75022.1 - 3.6e-09 36.2 13.3 0.031 14.1 0.0 7.7 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP75022.1 - 3.9e-09 35.9 16.2 0.1 12.7 0.1 8.0 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP75022.1 - 5.1e-09 36.5 19.8 0.036 14.6 0.2 7.2 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP75022.1 - 2.9e-08 33.5 8.7 4.6e-05 22.9 0.7 3.3 1 1 2 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 PRP75022.1 - 8.5e-07 29.5 9.8 0.0039 17.8 0.1 6.0 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP75022.1 - 3.3e-05 24.3 12.6 0.47 11.2 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat RPN7 PF10602.9 PRP75022.1 - 0.00038 20.2 20.3 0.01 15.6 2.1 4.3 2 2 0 3 3 3 2 26S proteasome subunit RPN7 Ter PF05472.11 PRP75022.1 - 0.00041 19.5 0.3 0.001 18.2 0.3 1.6 1 0 0 1 1 1 1 DNA replication terminus site-binding protein (Ter protein) ANAPC5 PF12862.7 PRP75022.1 - 0.0013 18.8 14.7 0.004 17.2 0.4 5.4 1 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 PHM7_cyt PF14703.6 PRP75022.1 - 0.0013 19.0 6.6 0.025 14.8 0.0 3.7 1 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter HHH_8 PF14716.6 PRP75022.1 - 0.015 15.7 3.8 0.41 11.1 0.2 3.6 4 0 0 4 4 2 0 Helix-hairpin-helix domain Hydrolase PF00702.26 PRP75022.1 - 0.019 15.3 0.9 0.048 13.9 0.5 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase ANAPC3 PF12895.7 PRP75022.1 - 0.023 14.9 17.1 0.13 12.5 1.3 5.2 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PRP75022.1 - 0.082 12.6 7.6 5.6 6.7 0.2 5.3 6 0 0 6 6 5 0 TPR repeat DIMCO_N PF16844.5 PRP75022.1 - 0.12 12.8 1.5 3.5 8.0 0.5 2.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Vta1_C PF18097.1 PRP75022.1 - 2.3 8.0 9.3 2.3 8.0 2.1 3.9 4 0 0 4 4 3 0 Vta1 C-terminal domain DUF2753 PF10952.8 PRP75022.1 - 2.9 8.0 8.7 0.51 10.5 0.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2753) BTAD PF03704.17 PRP75022.1 - 3.2 8.2 8.6 22 5.4 0.0 4.5 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Ceramidase PF05875.12 PRP75023.1 - 1.1e-46 159.4 12.2 1.3e-46 159.2 12.2 1.1 1 0 0 1 1 1 1 Ceramidase CrgA PF06781.12 PRP75023.1 - 0.4 10.8 0.1 0.4 10.8 0.1 2.9 3 1 0 3 3 3 0 Cell division protein CrgA Pro_isomerase PF00160.21 PRP75025.1 - 2.3e-45 154.7 0.0 5.1e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 PRP75025.1 - 2.5e-09 36.9 0.6 2.5e-09 36.9 0.6 2.9 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 PRP75025.1 - 1.9e-06 28.0 0.1 5.6e-05 23.2 0.0 2.5 1 1 1 2 2 2 1 U-box domain zf-Nse PF11789.8 PRP75025.1 - 0.00079 19.2 0.2 1.9 8.4 0.0 2.8 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 PRP75025.1 - 0.00084 19.4 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 PRP75025.1 - 0.031 14.3 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger adh_short PF00106.25 PRP75026.1 - 1e-16 61.0 2.9 8.6e-16 58.0 0.3 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP75026.1 - 6.8e-09 35.6 2.2 1.1e-07 31.7 0.3 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP75026.1 - 1.4e-05 25.1 0.5 3.1e-05 24.0 0.5 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP75026.1 - 0.057 13.3 0.2 0.086 12.7 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Cullin PF00888.22 PRP75027.1 - 7.5e-211 702.0 18.8 8.4e-211 701.8 18.8 1.0 1 0 0 1 1 1 1 Cullin family PIN_8 PF18476.1 PRP75027.1 - 2.3 8.0 5.8 0.35 10.7 0.5 2.3 3 0 0 3 3 3 0 PIN like domain Ank_2 PF12796.7 PRP75028.1 - 2e-34 118.0 0.1 1.1e-10 41.9 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PRP75028.1 - 6.3e-25 86.5 2.3 0.0011 19.4 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 PRP75028.1 - 7e-25 87.1 2.3 9e-08 32.5 0.1 5.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP75028.1 - 4.1e-24 84.3 0.7 2.4e-06 27.7 0.0 5.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75028.1 - 1.9e-23 80.0 0.2 0.011 16.2 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Chromo PF00385.24 PRP75029.1 - 4.6e-15 55.2 7.4 6.4e-07 29.2 0.9 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 PRP75029.1 - 3.9e-07 30.3 0.0 9.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF5514 PF17633.2 PRP75029.1 - 0.025 14.8 0.4 46 4.2 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5514) Mtf2_C PF14061.6 PRP75029.1 - 0.17 12.1 1.7 19 5.5 0.1 2.5 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.8 PRP75029.1 - 0.32 10.9 6.1 7.4 6.6 0.7 2.6 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Dimer_Tnp_hAT PF05699.14 PRP75030.1 - 0.00047 19.9 0.5 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Peptidase_C26 PF07722.13 PRP75032.1 - 2.1e-11 44.0 0.1 6.5e-11 42.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 PRP75032.1 - 0.00028 20.7 0.1 0.00061 19.6 0.1 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 PRP75032.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Methyltransf_23 PF13489.6 PRP75037.1 - 0.015 15.1 0.0 0.041 13.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain tRNA_edit PF04073.15 PRP75038.1 - 6.9e-08 32.6 0.0 1.2e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Pyr_redox_2 PF07992.14 PRP75039.1 - 1.2e-29 103.5 0.0 1.7e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 PRP75039.1 - 1.7e-20 71.0 12.2 3.4e-06 26.2 0.4 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PRP75039.1 - 2.8e-19 69.3 8.4 1e-11 45.1 1.4 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PRP75039.1 - 3.8e-17 60.7 7.9 3.3e-05 23.5 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PRP75039.1 - 1.4e-12 47.3 7.0 0.017 15.0 0.4 4.9 4 1 1 5 5 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PRP75039.1 - 7.2e-10 37.9 11.8 0.00064 19.1 1.4 4.5 4 0 0 4 4 4 3 EF hand GIDA PF01134.22 PRP75039.1 - 4e-05 22.9 0.2 0.036 13.1 0.4 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A SPARC_Ca_bdg PF10591.9 PRP75039.1 - 4.1e-05 23.9 5.5 0.074 13.4 0.1 3.5 1 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pyr_redox PF00070.27 PRP75039.1 - 0.00018 22.0 0.0 0.043 14.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP75039.1 - 0.0037 17.3 0.0 0.79 9.7 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding EF-hand_10 PF14788.6 PRP75039.1 - 0.013 15.3 8.0 0.57 10.1 0.0 3.8 4 1 1 5 5 5 0 EF hand DAO PF01266.24 PRP75039.1 - 0.018 14.6 0.1 6.9 6.1 0.0 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PRP75039.1 - 0.065 12.3 0.1 2 7.4 0.0 2.8 2 2 1 3 3 3 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 PRP75039.1 - 0.066 13.4 0.0 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 PRP75039.1 - 0.14 12.6 0.0 0.6 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 PRP75039.1 - 0.19 10.7 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain YolD PF08863.10 PRP75039.1 - 0.48 10.5 0.0 0.48 10.5 0.0 2.9 3 0 0 3 3 3 0 YolD-like protein Glyco_hyd_65N_2 PF14498.6 PRP75040.1 - 4.3e-14 52.9 0.0 7.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hyd_65N_2 PF14498.6 PRP75041.1 - 9.2e-08 32.2 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Sp38 PF07354.12 PRP75046.1 - 0.032 13.7 0.9 0.046 13.1 0.9 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) GvpL_GvpF PF06386.11 PRP75046.1 - 0.15 11.9 3.1 0.17 11.8 3.1 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF RIO1 PF01163.22 PRP75047.1 - 1.4e-06 28.0 0.1 2.4e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 PRP75047.1 - 1.6e-05 24.5 0.0 2.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP75047.1 - 0.00011 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3908 PF13048.6 PRP75047.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3908) Pkinase_fungal PF17667.1 PRP75047.1 - 0.11 11.2 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF4135 PF13575.6 PRP75047.1 - 0.12 11.7 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Pkinase_Tyr PF07714.17 PRP75050.1 - 4.8e-49 167.0 0.0 1.1e-48 165.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75050.1 - 2.5e-44 151.6 0.0 5.8e-44 150.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain FYVE PF01363.21 PRP75050.1 - 0.0012 18.9 2.2 0.012 15.8 2.2 2.3 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 PRP75050.1 - 0.0078 16.4 0.2 0.022 15.0 0.2 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Kinase-like PF14531.6 PRP75050.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Usp PF00582.26 PRP75051.1 - 0.00011 22.7 0.2 0.0059 17.1 0.0 2.1 2 0 0 2 2 2 2 Universal stress protein family NIF PF03031.18 PRP75052.1 - 8.1e-53 178.4 0.0 1.1e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 PRP75052.1 - 0.012 16.0 0.1 0.98 9.7 0.1 3.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 PRP75052.1 - 0.06 13.8 0.1 0.49 10.8 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DOT1 PF08123.13 PRP75053.1 - 8.1e-11 41.8 0.0 1.5e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 HlyD_D23 PF16576.5 PRP75053.1 - 0.0041 16.4 1.1 0.0078 15.5 1.1 1.3 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Methyltransf_4 PF02390.17 PRP75053.1 - 0.017 14.6 0.2 0.043 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase PCMT PF01135.19 PRP75053.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PDCD7 PF16021.5 PRP75053.1 - 0.27 10.3 11.9 0.42 9.7 11.9 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 NEMO PF11577.8 PRP75053.1 - 0.53 10.3 12.2 3 7.9 5.0 2.8 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Exo70 PF03081.15 PRP75059.1 - 7.4e-52 176.6 1.5 1.5e-51 175.6 1.5 1.5 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Sec34 PF04136.15 PRP75059.1 - 0.0036 17.2 0.1 0.016 15.1 0.1 2.1 1 0 0 1 1 1 1 Sec34-like family Fumble PF03630.14 PRP75060.1 - 1.7e-118 395.6 0.0 1.9e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 Fumble HHV-5_US34A PF17087.5 PRP75061.1 - 1.7 8.9 3.9 1.9 8.7 0.4 2.6 2 1 0 2 2 2 0 Herpesvirus US34A protein family DUF4407 PF14362.6 PRP75061.1 - 6.8 5.9 37.8 9.4 5.5 12.5 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF4618 PF15397.6 PRP75061.1 - 9.6 5.5 43.8 0.084 12.3 27.7 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) ATG27 PF09451.10 PRP75062.1 - 2.5e-15 57.1 0.0 8.4e-15 55.3 0.0 1.8 1 1 1 2 2 2 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 PRP75062.1 - 8.7e-10 38.1 0.0 1.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 PRP75062.1 - 0.0019 18.3 0.1 2.7 8.1 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF4064 PF13273.6 PRP75062.1 - 0.086 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) RasGAP PF00616.19 PRP75063.1 - 3.3e-17 62.9 0.0 2.9e-12 46.7 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase LRR_6 PF13516.6 PRP75063.1 - 9e-14 50.3 21.2 1.7e-05 24.5 0.1 8.2 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 PRP75063.1 - 4.2e-07 30.2 12.5 0.0041 17.5 2.0 4.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP75063.1 - 0.0034 17.1 12.0 0.032 14.0 3.5 3.7 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 PRP75063.1 - 0.014 15.8 7.5 16 6.5 0.6 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat TAL_FSA PF00923.19 PRP75063.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase Hexapep PF00132.24 PRP75064.1 - 0.00012 21.6 1.5 0.0017 18.0 0.3 3.0 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Nucleoporin_N PF08801.11 PRP75064.1 - 0.027 13.2 1.6 1 8.1 0.6 2.7 1 1 1 3 3 3 0 Nup133 N terminal like WD40 PF00400.32 PRP75064.1 - 0.14 13.1 2.0 11 7.0 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat Hira PF07569.11 PRP75064.1 - 0.15 11.7 4.1 0.58 9.8 0.0 3.1 3 1 0 3 3 3 0 TUP1-like enhancer of split Fib_alpha PF08702.10 PRP75065.1 - 0.0071 16.5 3.6 0.0071 16.5 3.6 2.7 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF3573 PF12097.8 PRP75065.1 - 0.13 11.1 3.6 0.074 11.9 1.1 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3573) Spc7 PF08317.11 PRP75065.1 - 0.35 9.7 21.0 0.047 12.6 8.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Sec8_exocyst PF04048.14 PRP75065.1 - 1.1 9.1 10.0 0.56 10.1 0.3 3.0 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain Phage_lysis PF03245.13 PRP75065.1 - 2.9 8.0 9.0 3.1 7.9 0.7 3.2 2 2 3 5 5 5 0 Bacteriophage Rz lysis protein APG6_N PF17675.1 PRP75065.1 - 3.3 8.2 24.1 6.8 7.2 11.7 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF745 PF05335.13 PRP75065.1 - 4 7.1 14.2 1.5 8.5 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Laminin_II PF06009.12 PRP75065.1 - 4.6 7.3 14.6 1.8 8.5 1.3 3.2 3 0 0 3 3 3 0 Laminin Domain II Syntaxin-6_N PF09177.11 PRP75065.1 - 6.8 7.3 14.8 2.3 8.8 4.9 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Plus-3 PF03126.18 PRP75066.1 - 7.6e-16 58.6 0.0 1.3e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Plus-3 domain Peptidase_M48 PF01435.18 PRP75067.1 - 6.5e-16 58.7 0.1 2.9e-15 56.6 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M48 DUF2275 PF10039.9 PRP75067.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) SprT-like PF10263.9 PRP75067.1 - 0.043 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 SprT-like family Synaptobrevin PF00957.21 PRP75067.1 - 0.046 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Synaptobrevin DNA_pol_A_exo1 PF01612.20 PRP75068.1 - 1.7e-09 37.6 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase_Tyr PF07714.17 PRP75069.1 - 5e-57 193.1 0.0 8.5e-57 192.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75069.1 - 3.8e-40 137.9 0.0 7.3e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pentapeptide_4 PF13599.6 PRP75069.1 - 0.011 15.9 4.2 2.3 8.5 0.2 4.3 5 0 0 5 5 5 0 Pentapeptide repeats (9 copies) Glyco_hydro_59M PF17387.2 PRP75069.1 - 7 6.8 6.7 4 7.6 0.1 3.5 4 0 0 4 4 4 0 Glycosyl hydrolase family 59 central domain zf-CCHC_3 PF13917.6 PRP75070.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle tRNA_synthFbeta PF17759.1 PRP75071.1 - 1.3e-47 162.0 0.0 1.9e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 PRP75071.1 - 7.4e-29 99.8 0.4 3.6e-27 94.4 0.1 3.0 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 PRP75071.1 - 3.5e-22 78.9 0.0 6.4e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 PRP75071.1 - 1.2e-17 64.0 0.1 1e-15 57.8 0.1 2.9 3 0 0 3 3 3 1 tRNA synthetase B5 domain DUF3239 PF11580.8 PRP75073.1 - 0.038 14.3 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3239) Ribosomal_S15 PF00312.22 PRP75074.1 - 0.012 15.8 0.7 0.061 13.5 0.7 2.1 2 0 0 2 2 2 0 Ribosomal protein S15 CAP59_mtransfer PF11735.8 PRP75075.1 - 2.8e-48 164.7 0.0 4.5e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Phage_CI_repr PF07022.13 PRP75075.1 - 0.0025 17.9 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 Bacteriophage CI repressor helix-turn-helix domain HTH_19 PF12844.7 PRP75075.1 - 0.045 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CS PF04969.16 PRP75076.1 - 1.6e-15 57.9 0.0 2.3e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 CS domain Helicase_C_2 PF13307.6 PRP75077.1 - 7.6e-45 153.1 0.1 2.5e-44 151.5 0.1 2.0 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 PRP75077.1 - 4.8e-40 137.1 0.8 1.3e-39 135.6 0.8 1.8 1 0 0 1 1 1 1 DEAD_2 DUF3883 PF13020.6 PRP75077.1 - 6.3e-06 26.2 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) SNF2_N PF00176.23 PRP75077.1 - 7.4e-05 21.6 0.1 0.00018 20.4 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 PRP75077.1 - 0.00014 21.7 1.7 0.08 12.7 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase HBB PF06777.11 PRP75077.1 - 0.0015 18.3 0.6 0.0069 16.1 0.0 2.3 2 0 0 2 2 2 1 Helical and beta-bridge domain PhoH PF02562.16 PRP75077.1 - 0.0035 16.8 0.3 0.89 9.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 PRP75077.1 - 0.025 14.6 1.9 0.054 13.5 0.1 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PTPRCAP PF15713.5 PRP75077.1 - 2.8 8.2 6.1 30 4.9 5.0 2.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Epimerase PF01370.21 PRP75079.1 - 3.3e-23 82.4 0.0 4.8e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 PRP75079.1 - 2.7e-13 49.7 0.0 2.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 PRP75079.1 - 5.7e-11 41.9 0.0 1.2e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PRP75079.1 - 6.9e-11 42.1 0.1 2.7e-10 40.2 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PRP75079.1 - 5.5e-09 36.2 0.0 7.7e-08 32.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 PRP75079.1 - 2.9e-07 30.3 0.2 4.9e-06 26.3 0.0 2.2 1 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 PRP75079.1 - 0.0011 18.4 0.2 0.0091 15.5 0.0 2.5 3 1 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 PRP75079.1 - 0.038 13.9 0.1 0.5 10.2 0.1 2.2 1 1 0 1 1 1 0 KR domain F420_oxidored PF03807.17 PRP75079.1 - 0.052 14.1 0.0 0.42 11.2 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent VIT1 PF01988.19 PRP75080.1 - 5.9e-47 160.3 0.8 9.1e-47 159.7 0.8 1.2 1 0 0 1 1 1 1 VIT family NADH_B2 PF14813.6 PRP75081.1 - 0.0012 18.6 0.6 0.0019 18.0 0.6 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 DEAD PF00270.29 PRP75082.1 - 2e-46 158.0 0.0 3.7e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP75082.1 - 6.1e-32 110.3 0.2 3.2e-31 108.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP75082.1 - 1.1e-05 25.5 0.1 4.1e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SIKE PF05769.11 PRP75082.1 - 0.048 13.6 7.0 1.6 8.6 0.8 2.5 2 0 0 2 2 2 0 SIKE family AAA_22 PF13401.6 PRP75082.1 - 0.056 13.7 0.4 0.29 11.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain RelE PF06296.12 PRP75082.1 - 0.21 11.7 4.2 0.31 11.2 1.0 2.6 3 0 0 3 3 3 0 RelE toxin of RelE / RelB toxin-antitoxin system X8 PF07983.13 PRP75083.1 - 5.4e-57 190.4 62.7 1.8e-09 38.2 5.5 6.6 6 0 0 6 6 6 6 X8 domain Glyco_hydro_17 PF00332.18 PRP75083.1 - 3.3e-06 26.9 1.7 6e-06 26.1 0.7 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF2989 PF11207.8 PRP75083.1 - 3.4e-06 27.0 11.4 0.059 13.1 0.0 6.1 7 0 0 7 7 7 2 Protein of unknown function (DUF2989) DUF226 PF02890.14 PRP75083.1 - 0.032 14.2 1.8 1.3 9.0 0.1 3.0 4 0 0 4 4 4 0 Borrelia family of unknown function DUF226 Talin_middle PF09141.10 PRP75083.1 - 0.2 11.7 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Talin, middle domain STATa_Ig PF18214.1 PRP75084.1 - 1.5e-34 118.6 0.7 3.1e-34 117.6 0.7 1.6 1 0 0 1 1 1 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 PRP75084.1 - 3e-33 114.1 0.3 3e-33 114.1 0.3 2.2 3 0 0 3 3 3 1 EF-hand fold domain Dict-STAT-coil PF09267.10 PRP75084.1 - 6.6e-11 42.6 10.1 6.6e-11 42.6 8.6 1.8 2 0 0 2 2 2 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 PRP75084.1 - 2.4e-07 30.7 0.0 5.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 PRP75084.1 - 0.026 14.4 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain CRT10 PF08728.10 PRP75086.1 - 0.43 8.7 4.3 0.65 8.1 4.2 1.2 1 1 0 1 1 1 0 CRT10 AAA_11 PF13086.6 PRP75087.1 - 1.1e-58 199.1 0.1 1.1e-58 199.1 0.1 3.3 2 1 0 2 2 1 1 AAA domain AAA_12 PF13087.6 PRP75087.1 - 9.1e-56 188.6 0.1 9.1e-56 188.6 0.1 2.4 3 1 0 3 3 1 1 AAA domain R3H PF01424.22 PRP75087.1 - 1.8e-14 53.4 1.4 4.6e-14 52.1 0.0 2.5 2 0 0 2 2 2 1 R3H domain AAA_30 PF13604.6 PRP75087.1 - 1.2e-12 47.9 0.0 1.8e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PRP75087.1 - 2e-09 37.9 0.0 1.2e-08 35.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PRP75087.1 - 1.3e-07 31.7 0.4 0.28 10.9 0.0 4.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-AN1 PF01428.16 PRP75087.1 - 4.6e-07 29.9 7.5 7.6e-07 29.2 7.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Helicase_RecD PF05127.14 PRP75087.1 - 1.4e-05 25.0 3.9 0.14 12.0 0.0 4.0 4 0 0 4 4 4 2 Helicase PhoH PF02562.16 PRP75087.1 - 5.7e-05 22.7 0.2 0.12 11.8 0.0 2.8 3 0 0 3 3 3 2 PhoH-like protein AAA_25 PF13481.6 PRP75087.1 - 6.5e-05 22.6 0.4 0.023 14.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 PRP75087.1 - 0.00048 20.5 0.2 0.0039 17.6 0.1 2.8 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP75087.1 - 0.00054 20.3 4.4 0.0059 16.9 0.0 3.8 3 0 0 3 3 3 1 AAA domain PIF1 PF05970.14 PRP75087.1 - 0.00067 18.9 0.1 0.11 11.6 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.21 PRP75087.1 - 0.0012 18.4 0.0 0.0012 18.4 0.0 3.6 2 2 2 4 4 4 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 PRP75087.1 - 0.003 16.9 8.6 0.0086 15.3 0.5 3.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 PRP75087.1 - 0.0032 16.6 0.5 0.045 12.8 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein CbiA PF01656.23 PRP75087.1 - 0.0038 17.3 0.0 0.016 15.3 0.0 2.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 PRP75087.1 - 0.0049 16.7 0.3 0.053 13.3 0.3 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP75087.1 - 0.0095 15.9 0.0 0.0095 15.9 0.0 3.7 2 2 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 PRP75087.1 - 0.017 15.5 0.0 0.017 15.5 0.0 2.2 2 1 0 2 2 1 0 AAA ATPase domain APS_kinase PF01583.20 PRP75087.1 - 0.021 14.7 0.2 0.61 10.0 0.0 3.1 3 0 0 3 3 3 0 Adenylylsulphate kinase MeaB PF03308.16 PRP75087.1 - 0.022 13.7 0.0 0.022 13.7 0.0 2.0 2 0 0 2 2 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 PRP75087.1 - 0.033 13.5 0.1 0.033 13.5 0.1 2.7 3 1 0 3 3 2 0 KaiC SRP54 PF00448.22 PRP75087.1 - 0.053 13.1 0.3 0.29 10.8 0.0 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_31 PF13614.6 PRP75087.1 - 0.075 12.9 1.0 0.31 10.9 1.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PRP75087.1 - 0.086 13.4 0.0 0.086 13.4 0.0 3.1 3 0 0 3 3 1 0 ABC transporter AAA_18 PF13238.6 PRP75087.1 - 0.23 12.0 0.1 0.23 12.0 0.1 3.6 2 1 1 3 3 2 0 AAA domain AAA_28 PF13521.6 PRP75087.1 - 0.87 9.8 7.0 0.93 9.7 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_6 PF12774.7 PRP75087.1 - 5.8 5.8 5.8 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Vps26 PF03643.15 PRP75088.1 - 1.1e-41 142.7 0.1 2.1e-41 141.8 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 LRR_8 PF13855.6 PRP75088.1 - 4.9e-33 112.7 65.4 9.5e-09 34.9 6.7 6.9 5 1 2 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PRP75088.1 - 3.8e-31 106.6 72.4 9.9e-07 29.0 2.2 8.6 6 2 1 8 8 8 8 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP75088.1 - 1.1e-28 100.2 0.4 1.7e-28 99.7 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75088.1 - 2.3e-20 73.1 0.3 3.7e-20 72.4 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP75088.1 - 2.9e-09 37.3 0.6 2.9e-09 37.3 0.6 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP75088.1 - 2.7e-06 27.2 63.7 0.43 11.3 0.1 15.2 13 3 2 15 15 15 5 Leucine Rich Repeat LRR_6 PF13516.6 PRP75088.1 - 0.02 14.9 38.8 0.89 9.8 0.5 8.3 9 0 0 9 9 9 0 Leucine Rich repeat Syndecan PF01034.20 PRP75088.1 - 0.1 12.5 0.4 0.22 11.4 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Stealth_CR2 PF11380.8 PRP75089.1 - 1.2e-45 154.2 0.3 2.3e-44 150.0 0.1 2.7 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 PRP75089.1 - 5.1e-16 58.3 4.8 1.6e-15 56.7 3.9 2.4 3 0 0 3 3 3 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 PRP75089.1 - 9.3e-16 57.5 0.3 2.5e-15 56.1 0.3 1.8 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Notch PF00066.17 PRP75089.1 - 2.3e-13 50.4 34.3 1e-06 29.1 15.8 2.8 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 PRP75089.1 - 1e-09 38.0 0.0 3.3e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 MULE PF10551.9 PRP75089.1 - 1.1e-05 25.7 0.0 2.9e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain WRKY PF03106.15 PRP75089.1 - 0.00021 21.4 3.1 0.00062 20.0 3.1 1.9 1 0 0 1 1 1 1 WRKY DNA -binding domain DDE_Tnp_ISL3 PF01610.17 PRP75089.1 - 0.017 14.9 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Transposase FLYWCH PF04500.16 PRP75089.1 - 0.13 12.4 2.1 0.28 11.3 1.4 2.0 1 1 0 1 1 1 0 FLYWCH zinc finger domain Aldo_ket_red PF00248.21 PRP75090.1 - 1.3e-44 152.6 0.2 3.2e-43 148.0 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF2540 PF10802.8 PRP75090.1 - 0.078 13.1 0.4 0.22 11.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) Thioredoxin_9 PF14595.6 PRP75090.1 - 0.15 11.8 0.5 0.39 10.5 0.5 1.6 1 0 0 1 1 1 0 Thioredoxin Pkinase_Tyr PF07714.17 PRP75091.1 - 2.3e-60 204.1 0.0 3.1e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75091.1 - 6.2e-50 170.0 0.0 9.8e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_18 PF00704.28 PRP75091.1 - 1.7e-25 90.4 0.3 4.4e-25 89.0 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 TPR_1 PF00515.28 PRP75091.1 - 1.1e-15 56.7 7.7 2e-05 24.2 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP75091.1 - 2.3e-11 42.9 5.8 0.0037 17.3 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP75091.1 - 1.1e-06 28.2 1.3 0.055 13.2 0.0 3.0 2 1 0 2 2 2 2 TPR repeat ANAPC3 PF12895.7 PRP75091.1 - 2.1e-05 24.7 3.4 7.3e-05 22.9 2.5 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP75091.1 - 0.00015 22.2 0.3 0.64 10.6 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Kinase-like PF14531.6 PRP75091.1 - 0.00019 20.9 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP75091.1 - 0.00095 18.6 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_16 PF13432.6 PRP75091.1 - 0.0015 19.2 0.1 0.082 13.6 0.0 2.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP75091.1 - 0.0033 17.5 6.7 0.013 15.6 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 PRP75091.1 - 0.0079 16.5 2.6 0.34 11.4 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP75091.1 - 0.01 16.4 1.7 0.82 10.4 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 PRP75091.1 - 0.022 13.7 0.6 0.032 13.1 0.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_12 PF13424.6 PRP75091.1 - 0.025 14.9 2.4 1.3 9.4 0.7 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Pkinase_fungal PF17667.1 PRP75091.1 - 0.043 12.6 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Herpes_gE PF02480.16 PRP75091.1 - 0.11 11.3 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mob1_phocein PF03637.17 PRP75092.1 - 1.2e-75 253.2 0.0 1.7e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.25 PRP75093.1 - 5.6e-78 262.0 0.0 9.1e-78 261.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75093.1 - 2.3e-33 115.6 0.0 3.9e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 PRP75093.1 - 5.8e-15 55.4 0.1 1.4e-14 54.2 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PRP75093.1 - 6.5e-11 42.4 0.0 1.7e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 PRP75093.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP75093.1 - 0.00033 20.1 0.3 0.00061 19.2 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3560 PF12083.8 PRP75093.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) APH PF01636.23 PRP75093.1 - 0.11 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PRP75094.1 - 7.2e-32 110.7 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75094.1 - 3.5e-25 88.9 0.0 6e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP75094.1 - 7.6e-10 39.2 6.2 2.1e-09 37.7 6.2 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP75094.1 - 0.00035 20.9 1.1 0.24 11.9 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP75094.1 - 0.00037 20.2 3.4 0.13 12.0 0.0 3.3 3 0 0 3 3 3 2 Leucine rich repeat Methyltransf_11 PF08241.12 PRP75095.1 - 4.7e-13 49.6 0.0 1.2e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP75095.1 - 3.6e-12 46.8 0.1 1.9e-11 44.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP75095.1 - 4.7e-12 46.1 0.0 7.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP75095.1 - 7.1e-12 45.4 0.3 2.8e-10 40.2 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP75095.1 - 4.4e-09 37.0 0.1 1.7e-08 35.1 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PRP75095.1 - 4.5e-09 36.5 0.0 2.9e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 PRP75095.1 - 0.00079 18.8 0.0 0.0075 15.6 0.0 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 PRP75095.1 - 0.0059 16.1 0.0 0.24 10.8 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase MetW PF07021.12 PRP75095.1 - 0.038 13.6 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW His_Phos_1 PF00300.22 PRP75096.1 - 1.2e-22 80.6 0.0 1.7e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ras PF00071.22 PRP75097.1 - 3.6e-52 176.2 0.4 4.2e-52 176.0 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP75097.1 - 1.5e-30 105.9 0.1 2.8e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP75097.1 - 4e-17 62.2 0.1 4.7e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP75097.1 - 2e-09 37.5 0.3 4.6e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP75097.1 - 1.1e-08 34.8 0.1 1.4e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP75097.1 - 7.6e-06 25.6 0.1 6.4e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP75097.1 - 8.5e-05 22.5 1.5 0.044 13.7 0.2 2.4 2 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 PRP75097.1 - 0.00012 21.9 0.6 0.0016 18.3 0.1 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 PRP75097.1 - 0.00061 19.5 0.1 0.012 15.4 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 PRP75097.1 - 0.00078 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 PRP75097.1 - 0.0052 17.2 0.1 0.021 15.3 0.0 1.9 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP75097.1 - 0.0087 16.5 0.0 0.014 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 PRP75097.1 - 0.02 14.6 0.3 0.083 12.6 0.1 2.0 1 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PRP75097.1 - 0.028 14.7 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 PRP75097.1 - 0.035 14.1 0.2 0.095 12.7 0.1 1.8 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 PRP75097.1 - 0.068 13.7 3.7 1.3 9.5 3.7 2.2 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 PRP75097.1 - 0.089 13.2 0.1 2.3 8.7 0.1 2.3 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 PRP75097.1 - 0.1 12.5 0.2 0.62 9.9 0.1 2.0 1 1 0 2 2 2 0 NTPase cobW PF02492.19 PRP75097.1 - 0.13 11.9 1.7 2.9 7.4 0.1 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 PRP75097.1 - 0.21 11.4 0.8 2 8.3 0.8 2.2 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) RAB3GAP2_N PF14655.6 PRP75098.1 - 6.2e-86 289.2 0.0 1.1e-85 288.4 0.0 1.4 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Myotub-related PF06602.14 PRP75101.1 - 2.3e-74 250.5 0.0 3.2e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.17 PRP75101.1 - 9.1e-57 192.3 0.0 1.4e-56 191.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75101.1 - 5.4e-43 147.2 0.0 8.5e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 PRP75101.1 - 1.2e-35 123.1 0.0 2.1e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain LRR_8 PF13855.6 PRP75101.1 - 7.2e-30 102.5 43.7 6.8e-10 38.6 0.2 7.1 2 1 1 6 6 6 6 Leucine rich repeat RhoGAP PF00620.27 PRP75101.1 - 5.4e-23 81.5 0.0 1.9e-22 79.7 0.0 2.0 2 0 0 2 2 1 1 RhoGAP domain LRR_4 PF12799.7 PRP75101.1 - 2e-21 75.7 49.7 0.0013 19.0 0.2 8.7 3 2 4 9 9 9 9 Leucine Rich repeats (2 copies) Roc PF08477.13 PRP75101.1 - 1.3e-15 57.7 0.0 2.6e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP75101.1 - 9.1e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Ras family LRR_9 PF14580.6 PRP75101.1 - 0.0057 16.2 12.9 0.033 13.7 0.3 4.0 1 1 1 4 4 4 2 Leucine-rich repeat FERM_f0 PF16511.5 PRP75101.1 - 0.016 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM MMR_HSR1 PF01926.23 PRP75101.1 - 0.046 13.8 0.0 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 PRP75101.1 - 0.055 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 PRP75101.1 - 0.092 12.2 0.2 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 PRP75101.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 PRP75102.1 - 2.5e-08 34.4 14.3 0.00013 22.6 0.6 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 PRP75102.1 - 0.031 13.6 0.0 0.96 8.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain SLX9 PF15341.6 PRP75103.1 - 9.2e-08 32.6 13.8 9.2e-08 32.6 13.8 3.0 2 1 1 3 3 3 1 Ribosome biogenesis protein SLX9 AMP-binding PF00501.28 PRP75104.1 - 8.2e-14 51.0 0.0 9.5e-13 47.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme SET PF00856.28 PRP75105.1 - 7.8e-13 49.2 0.1 1.4e-12 48.4 0.1 1.6 1 1 0 1 1 1 1 SET domain Arc_trans_TRASH PF08394.10 PRP75105.1 - 0.11 12.9 3.7 0.76 10.2 0.1 3.1 2 0 0 2 2 2 0 Archaeal TRASH domain GLTSCR1 PF15249.6 PRP75106.1 - 2.5e-08 34.3 0.1 6.3e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein CIMR PF00878.18 PRP75106.1 - 6.9e-05 23.0 1.0 0.0062 16.6 0.1 2.5 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat SARAF PF06682.12 PRP75106.1 - 8.7 5.9 14.0 0.069 12.8 4.9 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DOMON PF03351.17 PRP75107.1 - 1.3e-11 44.7 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 PRP75107.1 - 0.0074 16.1 9.2 0.0074 16.1 9.2 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) Pep_deformylase PF01327.21 PRP75108.1 - 1.4e-44 151.5 0.0 1.6e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase DUF4224 PF13986.6 PRP75108.1 - 0.048 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) XLF PF09302.11 PRP75109.1 - 3.8e-10 40.2 5.5 8.5e-10 39.1 4.2 2.2 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF4923 PF16270.5 PRP75109.1 - 0.087 12.6 0.6 4.8 7.0 0.1 2.4 2 1 0 2 2 2 0 Lipocalin-like domain (DUF4923) Cellulase PF00150.18 PRP75110.1 - 1.8e-28 99.8 0.0 4.4e-28 98.5 0.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 PRP75110.1 - 1.1e-11 45.2 0.1 2.9e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 PRP75110.1 - 0.00014 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 PRP75110.1 - 0.031 13.9 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Ras PF00071.22 PRP75111.1 - 2e-50 170.5 0.1 2.6e-50 170.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP75111.1 - 1.2e-19 70.7 0.0 1.9e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP75111.1 - 1e-08 34.9 0.2 1.2e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP75111.1 - 8.6e-06 25.4 0.1 2.4e-05 24.0 0.2 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP75111.1 - 0.0037 17.2 0.6 0.74 9.7 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP75111.1 - 0.0058 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4815 PF16075.5 PRP75111.1 - 0.046 12.0 0.1 0.067 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) Myosin_head PF00063.21 PRP75111.1 - 0.07 11.3 0.0 0.3 9.3 0.0 1.8 2 0 0 2 2 2 0 Myosin head (motor domain) SET PF00856.28 PRP75112.1 - 1.9e-09 38.1 0.0 4.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 PRP75112.1 - 0.00012 22.7 0.4 0.0025 18.5 0.6 2.3 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Acetyltransf_1 PF00583.25 PRP75113.1 - 4.8e-17 62.3 0.0 6.8e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP75113.1 - 5e-10 39.4 0.0 6.6e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP75113.1 - 1.2e-08 35.3 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP75113.1 - 1.8e-05 24.6 0.1 3.4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 PRP75113.1 - 0.0024 17.5 0.0 0.0035 17.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP75113.1 - 0.03 15.0 0.0 0.036 14.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP75113.1 - 0.049 13.7 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Homeodomain PF00046.29 PRP75114.1 - 3.7e-08 33.1 1.8 9.1e-08 31.8 1.8 1.7 1 0 0 1 1 1 1 Homeodomain Tmemb_9 PF05434.11 PRP75114.1 - 0.023 14.6 0.1 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 TMEM9 UQ_con PF00179.26 PRP75116.1 - 2.1e-28 98.7 0.1 4.3e-28 97.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-B_box PF00643.24 PRP75116.1 - 0.00034 20.7 14.5 0.00034 20.7 14.5 3.1 3 0 0 3 3 3 1 B-box zinc finger UEV PF05743.13 PRP75116.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 UEV domain zf-RING_14 PF17978.1 PRP75116.1 - 0.014 15.8 2.0 0.014 15.8 2.0 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Exonuc_VII_L PF02601.15 PRP75116.1 - 0.12 12.0 0.3 0.17 11.5 0.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Abhydrolase_1 PF00561.20 PRP75118.1 - 2.3e-31 109.4 0.0 3.2e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Scramblase PF03803.15 PRP75118.1 - 8.1e-13 48.2 0.0 1.9e-12 47.0 0.0 1.6 2 0 0 2 2 2 1 Scramblase Hydrolase_4 PF12146.8 PRP75118.1 - 7.6e-10 38.5 0.0 3.4e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP75118.1 - 1.4e-08 35.6 0.1 2.2e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Dehyd-heme_bind PF09098.10 PRP75118.1 - 0.00083 19.0 0.1 0.0029 17.3 0.0 1.7 2 0 0 2 2 2 1 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Abhydrolase_4 PF08386.10 PRP75118.1 - 0.027 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Ndr PF03096.14 PRP75118.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Reticulon PF02453.17 PRP75119.1 - 0.0012 18.8 2.0 0.0035 17.3 2.0 1.8 1 0 0 1 1 1 1 Reticulon Laminin_II PF06009.12 PRP75119.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Laminin Domain II IMUP PF15761.5 PRP75119.1 - 0.1 13.3 11.2 0.064 14.0 7.9 2.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein Tweety PF04906.13 PRP75119.1 - 9.2 4.8 19.5 1.4 7.5 3.8 3.3 1 1 1 2 2 2 0 Tweety OsmC PF02566.19 PRP75120.1 - 4.9e-18 65.5 0.0 1.1e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 OsmC-like protein SpoU_methylase PF00588.19 PRP75121.1 - 7.4e-24 84.5 0.0 1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 PRP75121.1 - 0.038 14.3 0.0 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding ASH PF15780.5 PRP75122.1 - 6.7e-05 23.0 6.9 0.38 11.0 0.1 5.5 6 0 0 6 6 6 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 PRP75122.1 - 0.00084 19.5 1.0 0.013 15.7 0.1 3.1 2 0 0 2 2 2 1 Transmembrane protein 131-like DUF1573 PF07610.11 PRP75122.1 - 0.00085 19.3 0.4 2.3 8.3 0.0 4.9 5 0 0 5 5 5 1 Protein of unknown function (DUF1573) PAS_8 PF13188.7 PRP75123.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain TruB_N PF01509.18 PRP75125.1 - 3.3e-47 160.6 0.0 6.1e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PRP75125.1 - 3.5e-06 27.1 0.1 5.8e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Tweety PF04906.13 PRP75126.1 - 0.0023 16.7 2.7 0.014 14.0 1.8 2.2 1 1 1 2 2 2 1 Tweety DUF3094 PF11293.8 PRP75126.1 - 0.043 13.5 0.2 0.71 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) 5_3_exonuc PF01367.20 PRP75126.1 - 0.12 13.0 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF2116 PF09889.9 PRP75126.1 - 2.3 8.2 5.9 7.3 6.7 0.7 3.5 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4792 PF16040.5 PRP75127.1 - 0.00057 19.7 0.2 0.0014 18.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4792) DUF4793 PF16041.5 PRP75127.1 - 0.068 13.3 0.1 0.25 11.5 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4793) DUF3662 PF12401.8 PRP75129.1 - 0.0076 16.6 1.2 0.018 15.4 0.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2662) CAS_CSE1 PF03378.15 PRP75129.1 - 0.1 11.0 2.9 0.14 10.6 2.9 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus DUF4407 PF14362.6 PRP75129.1 - 5 6.4 20.7 27 4.0 20.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Hormone_1 PF00103.20 PRP75129.1 - 6 6.5 11.5 11 5.7 7.3 2.8 1 1 1 2 2 2 0 Somatotropin hormone family PITH PF06201.13 PRP75130.1 - 1e-41 142.6 0.3 1.4e-41 142.3 0.3 1.2 1 0 0 1 1 1 1 PITH domain Ank_5 PF13857.6 PRP75131.1 - 2.6e-10 40.4 1.2 1.6e-06 28.3 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP75131.1 - 6.9e-10 39.4 0.1 1.3e-09 38.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75131.1 - 8.3e-10 39.0 0.2 3.6e-09 37.0 0.1 2.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP75131.1 - 6e-08 32.8 0.3 0.0054 17.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 PRP75131.1 - 1.5e-06 28.1 0.2 0.011 16.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat PAS PF00989.25 PRP75132.1 - 5.6e-05 23.1 0.0 8.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 PAS fold ADP_ribosyl_GH PF03747.14 PRP75133.1 - 2.1e-54 185.2 0.0 3.8e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LRR_8 PF13855.6 PRP75133.1 - 6.3e-23 80.3 29.3 8.1e-10 38.3 2.6 4.1 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 PRP75133.1 - 4.2e-19 68.3 35.7 7.4e-06 26.2 2.5 6.3 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP75133.1 - 1.5e-06 27.9 21.2 0.45 11.3 1.6 7.8 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 PRP75133.1 - 0.0012 18.4 17.5 0.46 10.0 0.7 3.6 1 1 1 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 PRP75133.1 - 0.046 13.7 5.6 0.33 10.9 0.9 2.9 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DUF98 PF01947.16 PRP75133.1 - 0.1 12.5 0.3 0.31 11.0 0.3 1.8 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase Gly-zipper_Omp PF13488.6 PRP75133.1 - 0.22 11.5 0.5 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Glycine zipper U1snRNP70_N PF12220.8 PRP75133.1 - 2.8 8.6 9.8 0.053 14.2 2.0 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal LRR_6 PF13516.6 PRP75133.1 - 8.6 6.7 35.2 7.7 6.9 0.7 8.0 9 0 0 9 9 9 0 Leucine Rich repeat RabGAP-TBC PF00566.18 PRP75134.1 - 1.2e-34 119.9 0.1 1.6e-34 119.4 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SAE2 PF08573.10 PRP75135.1 - 1.6e-07 32.4 13.6 1.2e-06 29.6 0.7 3.1 2 2 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Cys_rich_CPXG PF14255.6 PRP75135.1 - 0.13 12.2 1.0 0.29 11.1 1.0 1.6 1 0 0 1 1 1 0 Cysteine-rich CPXCG DUF4551 PF15087.6 PRP75135.1 - 0.61 8.9 4.0 0.68 8.7 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) UQ_con PF00179.26 PRP75136.1 - 3.4e-46 156.4 0.2 3.9e-46 156.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PRP75136.1 - 0.0028 17.9 0.1 0.0039 17.5 0.1 1.3 1 0 0 1 1 1 1 RWD domain CdiI_2 PF18593.1 PRP75136.1 - 0.026 15.2 0.4 0.085 13.5 0.1 1.9 2 0 0 2 2 2 0 CdiI immunity protein UEV PF05743.13 PRP75136.1 - 0.047 13.6 0.1 0.09 12.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 PRP75136.1 - 0.053 13.2 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Ank PF00023.30 PRP75139.1 - 0.0021 18.4 0.1 0.005 17.2 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 PRP75139.1 - 0.0032 17.9 0.1 0.0085 16.5 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 PRP75139.1 - 0.048 14.2 0.0 0.059 14.0 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) CDC4_D PF16856.5 PRP75140.1 - 0.094 12.6 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain DUF2277 PF10041.9 PRP75140.1 - 0.21 11.9 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) ATP-synt_ab PF00006.25 PRP75141.1 - 8.4e-108 358.9 0.0 1.3e-107 358.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 PRP75141.1 - 2.8e-41 140.2 0.0 5.2e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 PRP75141.1 - 1.1e-16 61.1 1.8 3.3e-16 59.5 1.8 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Phage_int_SAM_1 PF02899.17 PRP75142.1 - 0.018 15.3 0.1 0.025 14.9 0.1 1.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF3128 PF11326.8 PRP75143.1 - 3e-06 27.5 1.6 5.2e-06 26.7 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 PRP75143.1 - 0.014 15.6 0.6 0.027 14.7 0.6 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF2157 PF09925.9 PRP75144.1 - 0.026 14.3 0.3 0.051 13.4 0.3 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Pox_I5 PF04713.12 PRP75144.1 - 0.031 14.3 0.5 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Poxvirus protein I5 Sigma_reg_N PF13800.6 PRP75144.1 - 0.033 14.5 0.3 0.033 14.5 0.3 3.0 3 1 0 3 3 3 0 Sigma factor regulator N-terminal Comm PF15957.5 PRP75144.1 - 0.23 11.8 3.1 18 5.7 0.0 2.5 1 1 1 2 2 2 0 Commissureless Tetraspanin PF00335.20 PRP75144.1 - 0.47 10.1 8.8 7 6.3 8.8 2.1 1 1 0 1 1 1 0 Tetraspanin family DUF2644 PF10841.8 PRP75144.1 - 2.1 8.6 5.1 7.7 6.8 0.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2644) Menin PF05053.13 PRP75150.1 - 0.065 11.6 0.1 0.1 10.9 0.1 1.2 1 0 0 1 1 1 0 Menin WD40 PF00400.32 PRP75153.1 - 1e-08 35.7 5.2 4e-05 24.3 0.1 4.9 4 2 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75153.1 - 1.6e-06 28.3 0.0 0.0093 16.2 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Asp-B-Hydro_N PF05279.11 PRP75153.1 - 8.8 6.3 29.8 20 5.2 29.8 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Methyltransf_12 PF08242.12 PRP75154.1 - 0.11 13.3 0.4 1.9 9.3 0.1 2.7 2 1 1 3 3 3 0 Methyltransferase domain Allexi_40kDa PF05549.11 PRP75154.1 - 1.4 8.4 11.8 0.15 11.6 0.6 2.6 2 1 1 3 3 3 0 Allexivirus 40kDa protein BLOC1_2 PF10046.9 PRP75154.1 - 3.1 8.2 11.4 3.1 8.2 1.4 3.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.6 PRP75154.1 - 4.6 7.3 11.3 0.088 12.8 1.5 3.1 3 0 0 3 3 3 0 FlxA-like protein Pkinase_Tyr PF07714.17 PRP75155.1 - 4.2e-53 180.3 0.0 6.1e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75155.1 - 6e-52 176.6 0.0 8.7e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PRP75155.1 - 0.00035 19.6 0.0 0.00071 18.6 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain RA PF00788.23 PRP75155.1 - 0.00083 19.9 0.2 1.3 9.7 0.0 3.7 4 0 0 4 4 4 1 Ras association (RalGDS/AF-6) domain ubiquitin PF00240.23 PRP75155.1 - 0.0043 16.8 0.0 29 4.5 0.0 4.1 4 0 0 4 4 4 2 Ubiquitin family APH PF01636.23 PRP75155.1 - 0.0099 15.8 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Zn_clus PF00172.18 PRP75156.1 - 2.3e-06 27.6 12.9 4.4e-06 26.7 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Y_phosphatase2 PF03162.13 PRP75156.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PAS PF00989.25 PRP75156.1 - 0.078 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold MLTR_LBD PF17765.1 PRP75156.1 - 0.2 11.7 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain ERG4_ERG24 PF01222.17 PRP75157.1 - 5.5e-68 229.7 14.3 6.6e-68 229.4 14.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family adh_short PF00106.25 PRP75159.1 - 4e-29 101.5 0.2 7.1e-29 100.7 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP75159.1 - 2.1e-22 79.8 0.2 3.6e-22 79.1 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP75159.1 - 1.2e-06 28.6 0.1 2.3e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP75159.1 - 0.077 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Cid2 PF09774.9 PRP75159.1 - 9 6.7 8.0 21 5.5 2.4 2.5 2 0 0 2 2 2 0 Caffeine-induced death protein 2 PhoLip_ATPase_C PF16212.5 PRP75160.1 - 2.1e-71 240.6 19.8 2.1e-71 240.6 19.8 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP75160.1 - 3e-23 81.3 1.8 3e-23 81.3 1.8 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PRP75160.1 - 2.2e-10 41.2 1.6 0.00035 20.9 0.2 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PRP75160.1 - 2.5e-09 36.9 0.0 2.5e-09 36.9 0.0 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 PRP75160.1 - 3.5e-07 30.2 0.0 1.6e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP75160.1 - 4.4e-05 23.4 0.1 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1604 PF07713.13 PRP75161.1 - 0.3 11.0 3.8 0.24 11.3 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1604) HMG_box_2 PF09011.10 PRP75163.1 - 0.0046 17.5 0.1 0.0076 16.8 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain TPR_1 PF00515.28 PRP75164.1 - 2.9e-38 128.2 4.2 7.7e-09 35.0 0.4 7.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 PRP75164.1 - 7.1e-38 125.7 7.0 4.6e-07 29.5 0.3 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 PRP75164.1 - 5.9e-31 104.1 4.1 0.00022 21.2 0.5 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 PRP75164.1 - 2e-28 98.7 1.7 3.6e-07 30.7 0.0 5.8 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 PRP75164.1 - 5.8e-24 83.5 0.3 9.3e-07 28.4 0.0 7.9 5 1 4 9 9 9 3 TPR repeat TPR_12 PF13424.6 PRP75164.1 - 6.3e-22 77.7 12.6 5.4e-10 39.4 0.1 7.8 5 2 2 8 8 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP75164.1 - 2.2e-21 75.9 10.0 3.6e-07 30.3 2.2 5.4 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP75164.1 - 2e-20 73.0 1.7 2.1e-05 24.9 0.1 6.6 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 PRP75164.1 - 8.4e-18 63.4 3.9 0.19 12.2 0.0 8.4 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 PRP75164.1 - 2.7e-16 58.3 7.1 0.0015 18.5 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP75164.1 - 9.3e-16 57.2 7.1 0.15 13.0 0.0 8.4 5 1 5 10 10 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 PRP75164.1 - 1.8e-11 44.0 1.6 0.07 13.3 0.0 5.4 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 PRP75164.1 - 1e-09 38.0 11.1 0.0024 17.7 0.0 7.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP75164.1 - 4.2e-09 36.4 10.1 2.2 9.1 0.0 9.2 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_21 PF09976.9 PRP75164.1 - 1.2e-05 25.1 0.3 0.1 12.3 0.1 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat-like domain BTAD PF03704.17 PRP75164.1 - 0.0004 20.8 3.2 13 6.2 0.1 4.4 2 2 2 4 4 4 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 PRP75164.1 - 0.0029 18.1 2.6 7.8 7.4 0.0 5.0 7 0 0 7 7 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 PRP75164.1 - 0.004 17.4 1.1 11 6.4 0.4 4.4 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 PRP75164.1 - 0.0044 16.3 1.0 8.7 5.5 0.1 4.3 2 1 3 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 PRP75164.1 - 0.0047 17.0 1.2 4.2 7.4 0.2 3.3 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_MalT PF17874.1 PRP75164.1 - 0.0049 16.3 0.1 0.52 9.6 0.0 3.2 2 1 1 3 3 3 1 MalT-like TPR region DUF4810 PF16068.5 PRP75164.1 - 0.013 16.1 0.1 0.44 11.1 0.0 3.4 3 1 1 4 4 2 0 Domain of unknown function (DUF4810) PPR PF01535.20 PRP75164.1 - 0.014 15.6 0.6 20 5.7 0.0 4.3 4 0 0 4 4 4 0 PPR repeat FAT PF02259.23 PRP75164.1 - 0.019 14.2 0.2 0.48 9.6 0.1 2.7 1 1 1 2 2 2 0 FAT domain MIT PF04212.18 PRP75164.1 - 0.026 14.6 1.4 32 4.7 0.0 5.1 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 PRP75164.1 - 0.028 14.5 0.1 49 4.1 0.1 3.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 PRP75164.1 - 0.078 13.0 10.6 25 5.0 1.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat P-mevalo_kinase PF04275.14 PRP75164.1 - 0.23 11.4 0.6 6.4 6.8 0.1 2.9 3 0 0 3 3 2 0 Phosphomevalonate kinase NARP1 PF12569.8 PRP75164.1 - 0.64 8.8 3.7 9.3 5.0 0.1 3.0 2 1 0 3 3 3 0 NMDA receptor-regulated protein 1 Sel1 PF08238.12 PRP75164.1 - 1.4 9.7 4.5 62 4.5 0.0 4.1 5 0 0 5 5 3 0 Sel1 repeat GPCR_chapero_1 PF11904.8 PRP75165.1 - 2.7e-47 161.7 0.9 1.8e-27 96.6 0.9 2.3 1 1 1 2 2 2 2 GPCR-chaperone Ank_4 PF13637.6 PRP75165.1 - 1.2e-08 35.3 0.6 2.9e-05 24.5 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP75165.1 - 1.6e-07 31.8 0.1 2.5e-06 28.0 0.1 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP75165.1 - 2.8e-07 30.7 0.1 1.5e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75165.1 - 2.4e-05 24.4 0.2 0.0033 17.8 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 PRP75165.1 - 7.1e-05 23.1 0.1 0.0015 18.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat DTW PF03942.15 PRP75168.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 DTW domain Tfb2 PF03849.14 PRP75171.1 - 3.1e-111 371.8 4.7 3.7e-111 371.5 4.7 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 PRP75171.1 - 5.4e-16 58.8 0.0 1.5e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 PRP75171.1 - 0.0085 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain YIF1 PF03878.15 PRP75173.1 - 4.3e-68 229.4 9.2 5.5e-68 229.0 9.2 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 PRP75173.1 - 7.1e-08 32.4 4.9 1.3e-07 31.5 4.9 1.4 1 0 0 1 1 1 1 Yip1 domain GNAT_acetyltr_2 PF13718.6 PRP75174.1 - 1.1e-96 322.7 0.1 3.4e-96 321.1 0.0 1.9 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 PRP75174.1 - 4e-67 225.5 0.0 1.1e-66 224.1 0.0 1.8 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 PRP75174.1 - 6.7e-60 202.7 0.2 2.2e-59 201.0 0.0 1.9 2 0 0 2 2 2 1 Possible tRNA binding domain DUF1726 PF08351.11 PRP75174.1 - 2e-31 107.7 0.1 5.2e-31 106.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 PRP75174.1 - 0.00012 21.9 0.1 0.01 15.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 PRP75174.1 - 0.0038 17.5 0.0 0.78 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PRP75174.1 - 0.0097 16.3 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF742 PF05331.11 PRP75174.1 - 0.21 11.4 1.2 0.46 10.3 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF742) CLTH PF10607.9 PRP75175.1 - 4.4e-28 98.0 0.1 4.4e-28 98.0 0.1 2.1 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 PRP75175.1 - 2.1e-05 24.4 0.2 4e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger TelA PF05816.11 PRP75175.1 - 0.00051 19.2 3.5 0.072 12.1 1.8 2.2 1 1 1 2 2 2 2 Toxic anion resistance protein (TelA) Rtf2 PF04641.12 PRP75175.1 - 0.0055 16.1 0.0 0.0055 16.1 0.0 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 PRP75175.1 - 0.0066 16.8 0.2 0.014 15.7 0.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 PRP75175.1 - 0.028 14.2 0.7 0.083 12.7 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit EFTUD2 PF16004.5 PRP75175.1 - 0.038 14.6 0.5 0.068 13.8 0.5 1.4 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Pet127 PF08634.10 PRP75175.1 - 0.062 12.7 1.3 0.1 12.0 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet127 LAGLIDADG_WhiA PF14527.6 PRP75175.1 - 0.22 11.6 2.7 12 6.0 0.1 3.0 4 0 0 4 4 4 0 WhiA LAGLIDADG-like domain Goodbye PF17109.5 PRP75175.1 - 0.26 11.8 4.4 21 5.6 0.1 3.5 2 2 2 4 4 4 0 fungal STAND N-terminal Goodbye domain Acetyltransf_1 PF00583.25 PRP75176.1 - 3.8e-19 69.0 0.0 5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP75176.1 - 1.4e-10 41.4 0.0 2.1e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP75176.1 - 5e-10 39.4 0.0 6.7e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP75176.1 - 7.3e-10 39.2 0.1 8.5e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP75176.1 - 2.7e-05 24.2 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP75176.1 - 0.00017 22.2 0.0 0.00022 21.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP75176.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 PRP75176.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_6 PF13480.7 PRP75176.1 - 0.061 13.5 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PRA1 PF03208.19 PRP75177.1 - 4.4e-23 81.5 6.1 6.9e-23 80.9 6.1 1.3 1 0 0 1 1 1 1 PRA1 family protein DUF4389 PF14333.6 PRP75177.1 - 0.44 10.5 7.8 0.14 12.1 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) VirB3 PF05101.13 PRP75177.1 - 9.3 6.6 14.9 0.43 10.8 3.5 2.3 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF3169 PF11368.8 PRP75177.1 - 9.4 5.7 15.7 7.5 6.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Histone PF00125.24 PRP75179.1 - 1.8e-06 28.3 0.1 0.00044 20.6 0.0 2.5 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 Ank_4 PF13637.6 PRP75179.1 - 0.0014 19.2 0.0 0.0039 17.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) F-box PF00646.33 PRP75179.1 - 0.0036 17.2 4.4 0.14 12.1 0.1 3.1 2 1 0 2 2 2 2 F-box domain Ank_2 PF12796.7 PRP75179.1 - 0.014 15.9 0.0 0.057 14.0 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) F-box-like PF12937.7 PRP75179.1 - 9.6 6.2 10.2 0.33 10.9 0.3 3.2 3 0 0 3 3 3 0 F-box-like Pkinase PF00069.25 PRP75181.1 - 0.013 14.9 0.1 0.013 14.9 0.1 1.0 1 0 0 1 1 1 0 Protein kinase domain PAS_5 PF07310.13 PRP75181.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.0 1 0 0 1 1 1 0 PAS domain WD40 PF00400.32 PRP75182.1 - 2.2e-29 101.0 9.7 2.3e-06 28.2 0.6 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat LisH_TPL PF17814.1 PRP75182.1 - 5.4e-13 48.4 0.1 1.1e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain ANAPC4_WD40 PF12894.7 PRP75182.1 - 2.8e-11 43.5 0.5 0.00012 22.3 0.1 5.3 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP75182.1 - 4.8e-08 32.3 2.6 0.014 14.4 0.3 3.7 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP75182.1 - 1.3e-07 30.7 3.2 0.0065 15.2 0.2 4.0 2 1 1 4 4 4 3 Nucleoporin Nup120/160 SdiA-regulated PF06977.11 PRP75182.1 - 0.022 14.0 0.0 0.057 12.6 0.0 1.7 1 0 0 1 1 1 0 SdiA-regulated PALB2_WD40 PF16756.5 PRP75182.1 - 0.064 12.2 0.8 0.4 9.5 0.1 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SNN_linker PF09050.10 PRP75182.1 - 0.28 11.0 2.1 0.6 9.9 2.1 1.6 1 0 0 1 1 1 0 Stannin unstructured linker Zap1_zf2 PF18217.1 PRP75182.1 - 0.73 9.9 4.0 2.7 8.1 0.4 2.7 2 0 0 2 2 2 0 Zap1 zinc finger 2 DnaJ PF00226.31 PRP75183.1 - 1.8e-24 85.6 0.8 3.5e-24 84.7 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain LRR_8 PF13855.6 PRP75183.1 - 2.6e-22 78.4 18.0 1.6e-11 43.8 1.8 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PRP75183.1 - 1.3e-19 69.9 12.0 5.3e-07 29.9 0.7 4.1 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP75183.1 - 4.5e-07 29.5 3.9 0.00019 21.0 0.5 2.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 PRP75183.1 - 4.9e-07 29.4 7.9 1.2 10.0 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP75183.1 - 0.0047 16.9 15.2 3.7 7.9 0.1 6.4 7 0 0 7 7 7 1 Leucine Rich repeat RsmF_methylt_CI PF17126.5 PRP75183.1 - 0.035 14.1 0.2 4.5 7.4 0.0 3.0 2 1 1 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain Dynamin_M PF01031.20 PRP75185.1 - 0.0089 15.3 0.5 0.011 15.0 0.5 1.2 1 0 0 1 1 1 1 Dynamin central region Phasin_2 PF09361.10 PRP75185.1 - 0.019 15.2 2.1 0.28 11.5 0.7 2.5 3 0 0 3 3 3 0 Phasin protein Linker_histone PF00538.19 PRP75185.1 - 0.11 12.9 0.1 21 5.6 0.1 2.5 1 1 1 2 2 2 0 linker histone H1 and H5 family ATP-synt_G PF04718.15 PRP75185.1 - 0.23 12.3 2.6 0.6 11.0 0.1 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase g subunit MHB PF16525.5 PRP75185.1 - 0.33 11.2 2.0 0.93 9.8 1.5 2.0 2 0 0 2 2 2 0 Haemophore, haem-binding PLRV_ORF5 PF01690.17 PRP75188.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DDE_Tnp_4 PF13359.6 PRP75189.1 - 5.6e-12 45.6 0.0 6.7e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.6 PRP75189.1 - 0.071 13.5 0.2 0.16 12.3 0.2 1.6 1 1 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1 PF01609.21 PRP75189.1 - 0.13 11.9 0.5 0.22 11.1 0.5 1.6 1 1 0 1 1 1 0 Transposase DDE domain dCMP_cyt_deam_1 PF00383.23 PRP75190.1 - 0.06 13.2 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Bee_toxin PF17454.2 PRP75190.1 - 0.066 13.3 0.2 0.095 12.8 0.2 1.3 1 0 0 1 1 1 0 Honey bee toxin Pkinase_Tyr PF07714.17 PRP75193.1 - 1.7e-47 161.9 0.0 2.1e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75193.1 - 1.7e-27 96.5 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 PRP75193.1 - 0.00059 19.8 0.1 0.00097 19.1 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 PRP75193.1 - 0.0047 17.8 0.2 0.0099 16.7 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PRP75193.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4051 PF13260.6 PRP75193.1 - 0.017 14.8 0.2 0.035 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Herpes_gE PF02480.16 PRP75193.1 - 0.023 13.5 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3377 PF11857.8 PRP75193.1 - 0.023 14.6 0.2 0.061 13.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Pilin_N PF07790.11 PRP75193.1 - 0.027 15.4 1.2 0.52 11.3 1.4 2.4 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal RIFIN PF02009.16 PRP75193.1 - 0.032 14.1 0.2 0.052 13.4 0.2 1.3 1 0 0 1 1 1 0 Rifin LST1 PF05083.13 PRP75193.1 - 0.044 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 LST-1 protein DUF3827 PF12877.7 PRP75193.1 - 0.065 11.6 0.1 0.42 8.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) PRIMA1 PF16101.5 PRP75193.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DAG1 PF05454.11 PRP75193.1 - 0.18 11.1 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Amnionless PF14828.6 PRP75193.1 - 0.19 10.5 0.2 0.27 10.0 0.2 1.1 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 PRP75193.1 - 0.2 11.2 0.1 0.39 10.2 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Insulin_TMD PF17870.1 PRP75193.1 - 7.1 6.8 8.6 16 5.6 8.2 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment RNHCP PF12647.7 PRP75194.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 RNHCP domain RVT_1 PF00078.27 PRP75196.1 - 0.0024 17.4 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MTTB PF06253.11 PRP75196.1 - 0.081 10.9 0.0 0.11 10.5 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) DUF1541 PF07563.11 PRP75198.1 - 0.15 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) FAD_binding_7 PF03441.14 PRP75200.1 - 2.1e-74 249.4 3.3 5.3e-74 248.1 2.9 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PRP75200.1 - 1e-32 113.4 0.0 2e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase AP_endonuc_2 PF01261.24 PRP75200.1 - 0.00012 21.6 0.0 0.00029 20.3 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Usp PF00582.26 PRP75200.1 - 0.0044 17.5 0.3 0.036 14.6 0.0 2.4 2 0 0 2 2 2 1 Universal stress protein family NPR3 PF03666.13 PRP75200.1 - 0.83 8.4 5.4 1.3 7.8 5.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 E1-E2_ATPase PF00122.20 PRP75201.1 - 2.7e-23 82.4 0.0 6.4e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 PRP75201.1 - 1.2e-09 38.8 0.0 0.001 19.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP75201.1 - 8.9e-07 28.9 0.0 2.4e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP75201.1 - 0.0016 18.2 0.1 0.045 13.5 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ThiF PF00899.21 PRP75202.1 - 0.00016 21.2 0.2 0.00049 19.5 0.1 1.7 2 0 0 2 2 2 1 ThiF family zf-CCHC_3 PF13917.6 PRP75203.1 - 7.6e-14 51.4 8.0 1.3e-13 50.7 8.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 PRP75203.1 - 0.038 14.1 4.9 0.062 13.4 4.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Band_3_cyto PF07565.13 PRP75203.1 - 0.31 10.8 2.7 0.38 10.5 2.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDK2AP PF09806.9 PRP75203.1 - 0.35 10.9 6.8 0.6 10.1 6.8 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PI3K_1B_p101 PF10486.9 PRP75203.1 - 0.35 8.6 10.7 0.36 8.6 10.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 PRP75203.1 - 0.59 8.6 15.3 0.66 8.5 15.3 1.1 1 0 0 1 1 1 0 Macoilin family NPR3 PF03666.13 PRP75203.1 - 2 7.1 14.6 2.1 7.1 14.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SPX PF03105.19 PRP75203.1 - 2.8 7.8 28.4 3.6 7.4 28.4 1.2 1 0 0 1 1 1 0 SPX domain Pkinase_fungal PF17667.1 PRP75203.1 - 2.8 6.6 8.4 3 6.5 8.4 1.2 1 0 0 1 1 1 0 Fungal protein kinase Presenilin PF01080.17 PRP75203.1 - 6.3 5.4 11.2 7 5.3 11.2 1.3 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 PRP75204.1 - 1.2e-65 218.0 0.1 1.1e-09 38.7 0.0 7.6 3 1 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75204.1 - 2.3e-48 161.9 18.8 4.8e-07 30.2 0.1 11.9 11 3 2 13 13 13 9 Ankyrin repeats (many copies) CEP76-C2 PF15627.6 PRP75204.1 - 1.1e-29 103.0 0.0 2.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain Ank_3 PF13606.6 PRP75204.1 - 1.3e-29 98.9 5.8 2.2 9.1 0.0 17.4 19 0 0 19 19 19 6 Ankyrin repeat Ank_5 PF13857.6 PRP75204.1 - 1.6e-27 95.2 11.6 0.013 15.8 0.0 14.0 5 4 10 15 15 15 8 Ankyrin repeats (many copies) Ank PF00023.30 PRP75204.1 - 5.7e-25 86.6 15.8 0.58 10.7 0.0 16.6 18 1 0 18 18 18 5 Ankyrin repeat Hairy_orange PF07527.13 PRP75204.1 - 9.4 6.5 8.5 1.2e+02 3.0 0.0 6.4 10 0 0 10 10 10 0 Hairy Orange Ank_2 PF12796.7 PRP75206.1 - 1.1e-52 176.5 0.0 2.9e-10 40.6 0.0 6.4 3 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75206.1 - 1.7e-45 152.8 6.7 3.2e-07 30.7 0.1 11.1 7 3 4 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 PRP75206.1 - 1.3e-31 107.6 9.0 0.067 13.7 0.0 13.9 14 0 0 14 14 14 7 Ankyrin repeat Ank_5 PF13857.6 PRP75206.1 - 1e-29 102.2 3.0 0.015 15.6 0.0 13.0 5 4 10 15 15 15 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75206.1 - 8.1e-27 90.3 0.0 0.66 10.7 0.0 13.3 14 0 0 14 14 14 6 Ankyrin repeat DUF1403 PF07183.11 PRP75206.1 - 2e-06 27.6 9.2 0.35 10.4 0.2 7.3 3 2 7 10 10 10 2 Protein of unknown function (DUF1403) DUF3734 PF12536.8 PRP75206.1 - 0.00032 21.0 4.0 17 5.8 0.0 6.2 3 1 4 7 7 7 0 Patatin phospholipase YlzJ PF14035.6 PRP75206.1 - 0.0032 17.6 0.0 67 3.8 0.0 5.8 8 0 0 8 8 7 0 YlzJ-like protein Methyltransf_24 PF13578.6 PRP75206.1 - 0.13 13.3 9.4 3.1 8.9 1.0 5.3 3 2 2 5 5 5 0 Methyltransferase domain Hairy_orange PF07527.13 PRP75206.1 - 0.21 11.9 5.2 83 3.5 0.0 7.0 9 0 0 9 9 9 0 Hairy Orange ADSL_C PF10397.9 PRP75206.1 - 5.1 7.7 6.3 3.1e+02 2.0 0.2 5.9 3 3 3 6 6 6 0 Adenylosuccinate lyase C-terminus rve PF00665.26 PRP75208.1 - 3.6e-12 46.5 0.0 8.6e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain Mg_chelatase PF01078.21 PRP75210.1 - 0.73 9.2 2.9 0.82 9.0 1.9 1.5 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI HECT PF00632.25 PRP75213.1 - 1.3e-51 175.9 1.4 2.4e-32 112.7 0.3 2.4 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) CPSF100_C PF13299.6 PRP75213.1 - 0.043 14.0 2.2 0.12 12.5 2.2 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sec7_N PF12783.7 PRP75213.1 - 0.25 11.2 8.1 6 6.7 0.7 3.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Pox_Ag35 PF03286.14 PRP75213.1 - 0.34 10.7 4.8 0.87 9.3 4.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 PRP75213.1 - 0.35 8.9 10.6 0.89 7.6 10.6 1.6 1 0 0 1 1 1 0 DNA polymerase phi DUF5523 PF17661.1 PRP75213.1 - 0.38 10.4 13.1 0.69 9.6 9.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Polysacc_syn_2C PF08485.10 PRP75214.1 - 0.0042 16.7 0.1 4.3 7.1 0.0 2.7 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein C-terminal Pkinase_Tyr PF07714.17 PRP75215.1 - 4.9e-06 26.0 0.0 0.0035 16.7 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase TFIIA_gamma_N PF02268.16 PRP75215.1 - 1.1e-05 25.3 0.2 3.7e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain V-ATPase_G PF03179.15 PRP75215.1 - 0.0039 17.7 17.4 0.0039 17.7 17.4 3.4 1 1 2 3 3 3 2 Vacuolar (H+)-ATPase G subunit TFIIA_gamma_C PF02751.14 PRP75215.1 - 0.011 15.9 0.1 0.029 14.5 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit TFA2_Winged_2 PF18121.1 PRP75215.1 - 0.04 13.6 1.9 4.3 7.1 0.4 2.7 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Pkinase PF00069.25 PRP75216.1 - 6.4e-70 235.5 0.3 1.2e-69 234.7 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75216.1 - 2.8e-37 128.4 0.1 7.6e-37 127.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PAS PF00989.25 PRP75216.1 - 4.8e-21 74.9 0.0 3.1e-08 33.6 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 PRP75216.1 - 6.4e-20 71.3 0.0 4.3e-07 30.1 0.0 4.5 4 1 0 4 4 4 3 PAS domain Kinase-like PF14531.6 PRP75216.1 - 5.8e-10 39.0 0.0 8.5e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAS_4 PF08448.10 PRP75216.1 - 1.4e-06 28.5 0.0 0.52 10.6 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.12 PRP75216.1 - 1.7e-05 25.0 0.0 1.7 9.0 0.0 4.3 4 0 0 4 4 4 2 PAS fold Pkinase_fungal PF17667.1 PRP75216.1 - 0.00024 20.0 0.0 0.00038 19.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP75216.1 - 0.0021 17.1 0.3 0.0031 16.5 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP75216.1 - 0.0091 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS_8 PF13188.7 PRP75216.1 - 0.026 14.6 0.0 3 8.0 0.0 3.1 3 0 0 3 3 3 0 PAS domain DUF1280 PF06918.14 PRP75217.1 - 0.016 14.8 0.2 0.055 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1280) Peptidase_S76 PF13611.6 PRP75217.1 - 0.13 12.6 0.2 0.58 10.5 0.2 2.1 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Polysacc_synt_4 PF04669.13 PRP75218.1 - 6.3e-13 48.7 0.7 1.2e-10 41.3 0.1 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis PIG-U PF06728.13 PRP75220.1 - 7.4e-93 311.6 42.5 1e-92 311.2 42.5 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 PRP75220.1 - 1.1 8.9 37.6 0.016 14.9 25.7 2.4 1 1 1 2 2 2 0 8TM Microsporidial transmembrane domain NUDIX PF00293.28 PRP75221.1 - 2.3e-05 24.5 0.0 0.00036 20.6 0.0 2.7 1 1 0 1 1 1 1 NUDIX domain DUF2076 PF09849.9 PRP75223.1 - 0.48 10.4 20.1 0.25 11.3 8.9 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) LRR_8 PF13855.6 PRP75224.1 - 3.9e-112 366.0 188.7 9.9e-12 44.4 3.7 26.5 14 9 12 28 28 28 26 Leucine rich repeat LRR_4 PF12799.7 PRP75224.1 - 1.7e-68 225.4 218.2 7.3e-07 29.4 1.8 34.7 16 7 27 44 44 44 33 Leucine Rich repeats (2 copies) His_Phos_1 PF00300.22 PRP75224.1 - 2e-20 73.4 0.1 3.2e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LRR_1 PF00560.33 PRP75224.1 - 1.1e-09 37.5 155.7 0.38 11.5 0.1 36.5 43 5 2 45 45 45 14 Leucine Rich Repeat Pkinase PF00069.25 PRP75225.1 - 1.5e-48 165.5 0.0 2.1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75225.1 - 2.2e-30 105.8 0.0 3.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP75225.1 - 7.8e-07 28.2 0.0 1.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP75225.1 - 2e-06 27.3 0.2 3.9e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP75225.1 - 9.6e-06 25.7 0.7 0.0015 18.5 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 PRP75225.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP75225.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Claudin_2 PF13903.6 PRP75226.1 - 0.28 10.9 7.1 0.39 10.4 7.1 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TMEM132D_C PF15706.5 PRP75226.1 - 0.51 10.2 2.7 20 5.1 0.0 2.2 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF1700 PF08006.11 PRP75226.1 - 0.91 9.0 7.8 1.3 8.5 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF4231 PF14015.6 PRP75226.1 - 6.4 7.3 5.0 3.3 8.2 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PhyH PF05721.13 PRP75227.1 - 3.8e-37 128.6 0.0 5.4e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 PRP75228.1 - 2e-81 274.2 15.6 1.3e-61 208.8 4.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PRP75228.1 - 2.9e-27 95.5 47.3 5.1e-23 81.6 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PRP75228.1 - 0.003 16.9 8.4 0.003 16.9 8.4 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 PRP75228.1 - 0.022 13.2 9.5 0.015 13.8 4.2 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3603 PF12227.8 PRP75228.1 - 0.12 11.6 0.1 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3603) DUF4191 PF13829.6 PRP75228.1 - 3.5 6.9 5.8 0.63 9.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Halogen_Hydrol PF10112.9 PRP75228.1 - 6.5 6.7 5.9 11 6.0 0.1 3.1 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein zf-CCCH_3 PF15663.5 PRP75231.1 - 1.7e-14 54.0 12.8 1.5e-12 47.7 4.9 2.7 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH PF00642.24 PRP75231.1 - 0.002 18.0 1.0 0.002 18.0 1.0 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PRP75231.1 - 0.003 17.9 21.4 0.011 16.2 2.0 3.2 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 PRP75231.1 - 0.007 16.4 2.1 0.007 16.4 2.1 3.3 3 0 0 3 3 3 2 Zinc finger domain DUF2461 PF09365.10 PRP75231.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) V_ATPase_I PF01496.19 PRP75231.1 - 0.055 11.4 0.4 0.091 10.7 0.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Torus PF16131.5 PRP75231.1 - 0.11 13.2 22.5 0.21 12.3 2.3 4.0 2 1 2 4 4 4 0 Torus domain Myc-LZ PF02344.15 PRP75231.1 - 0.88 9.7 6.7 1.8 8.7 6.7 1.5 1 0 0 1 1 1 0 Myc leucine zipper domain UPF0242 PF06785.11 PRP75231.1 - 1.9 8.6 6.6 0.17 12.0 0.8 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TBX PF12598.8 PRP75232.1 - 0.056 14.2 0.4 0.11 13.3 0.4 1.5 1 0 0 1 1 1 0 T-box transcription factor EF-hand_1 PF00036.32 PRP75234.1 - 1.5e-12 46.1 3.8 3.5e-05 23.0 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PRP75234.1 - 2.3e-12 47.2 0.8 2.4e-07 31.1 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP75234.1 - 1.3e-11 43.4 0.4 0.0091 15.9 0.1 4.1 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 PRP75234.1 - 2.5e-09 36.8 7.1 8.1e-05 22.4 0.1 4.0 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 PRP75234.1 - 1.8e-05 25.0 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Adenine_glyco PF03352.13 PRP75234.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase FDX-ACB PF03147.14 PRP75234.1 - 0.017 15.5 0.5 0.58 10.6 0.0 2.6 2 1 1 3 3 3 0 Ferredoxin-fold anticodon binding domain EF-hand_5 PF13202.6 PRP75234.1 - 0.16 11.6 7.4 0.41 10.2 0.0 4.0 4 1 0 4 4 4 0 EF hand PHO4 PF01384.20 PRP75235.1 - 3.7e-50 170.9 2.8 4.2e-50 170.7 2.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF742 PF05331.11 PRP75235.1 - 0.0042 16.9 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Tautomerase PF01361.21 PRP75235.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme LRR_4 PF12799.7 PRP75237.1 - 5.7e-10 39.3 11.9 4.9e-06 26.8 0.8 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP75237.1 - 5.3e-08 32.5 10.8 0.00036 20.3 0.8 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 PRP75237.1 - 8.6e-06 25.4 2.9 1.7e-05 24.4 2.9 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PRP75237.1 - 6.5e-05 22.7 11.3 0.86 9.8 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 PRP75237.1 - 1.8 9.4 12.4 38 5.4 0.2 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat PIG-Y PF15159.6 PRP75240.1 - 1.5e-16 61.0 3.2 1.8e-16 60.8 3.2 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Peptidase_M28 PF04389.17 PRP75241.1 - 4.1e-29 101.7 0.0 1e-28 100.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 PRP75241.1 - 2.5e-07 30.6 0.0 6e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4395 PF14340.6 PRP75242.1 - 1.2e-13 51.5 5.1 1.6e-13 51.1 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4395) Nucleoplasmin PF03066.15 PRP75244.1 - 0.041 14.4 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain MFS_1 PF07690.16 PRP75245.1 - 6.9e-17 61.4 49.1 2e-11 43.4 20.7 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PRP75245.1 - 9.7e-07 27.7 30.0 0.00021 20.0 19.8 3.0 1 1 1 2 2 2 2 MFS/sugar transport protein MTS PF05175.14 PRP75246.1 - 6.1e-06 25.9 0.0 4e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP75246.1 - 2.7e-05 24.8 0.0 5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP75246.1 - 0.00076 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP75246.1 - 0.00077 20.1 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 PRP75246.1 - 0.0026 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 PRP75246.1 - 0.017 15.8 0.0 0.048 14.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CmcI PF04989.12 PRP75246.1 - 0.095 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Amidase PF01425.21 PRP75247.1 - 3.7e-16 59.1 0.0 5.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 PRP75248.1 - 1.2e-54 186.0 0.1 1.3e-54 185.8 0.1 1.0 1 0 0 1 1 1 1 Amidase LRR_8 PF13855.6 PRP75249.1 - 3e-11 42.9 50.5 0.1 12.4 0.6 10.4 8 2 2 10 10 10 6 Leucine rich repeat LRR_4 PF12799.7 PRP75249.1 - 3.8e-08 33.5 59.1 0.011 16.1 0.6 10.9 5 5 7 12 12 12 6 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PRP75249.1 - 0.00024 21.4 0.2 0.00056 20.2 0.2 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PRP75249.1 - 0.0028 17.6 37.6 1.7 8.9 0.1 10.3 11 0 0 11 11 11 4 Leucine Rich repeat Ig_C19orf38 PF17737.1 PRP75251.1 - 0.0026 18.1 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Ig domain in C19orf38 (HIDE1) UBA_e1_thiolCys PF10585.9 PRP75251.1 - 0.03 14.2 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site malic PF00390.19 PRP75251.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain V_ATPase_I PF01496.19 PRP75252.1 - 0.064 11.2 18.7 0.073 11.0 18.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_22 PF13401.6 PRP75253.1 - 0.03 14.6 0.0 0.099 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2252 PF10009.9 PRP75256.1 - 0.02 14.0 0.6 0.026 13.6 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF719 PF05334.13 PRP75256.1 - 0.083 13.1 0.3 0.14 12.3 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF719) Poxvirus_B22R PF04395.12 PRP75256.1 - 0.33 10.5 2.8 0.45 10.0 0.2 2.0 1 1 0 2 2 2 0 Poxvirus B22R protein Hrs_helical PF12210.8 PRP75257.1 - 0.016 15.7 0.4 0.017 15.6 0.4 1.1 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Arf PF00025.21 PRP75260.1 - 6.1e-33 113.7 0.1 8.1e-33 113.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP75260.1 - 1.2e-09 37.9 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP75260.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP75260.1 - 6.7e-06 25.8 1.4 0.00023 20.8 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 PRP75260.1 - 5.8e-05 22.8 3.9 0.0062 16.2 0.1 2.1 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 PRP75260.1 - 8.8e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PRP75260.1 - 0.00046 20.4 0.3 0.0011 19.2 0.3 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PRP75260.1 - 0.0069 16.3 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PRP75260.1 - 0.01 16.1 3.4 0.14 12.4 0.2 2.8 2 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 PRP75260.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 PRP75260.1 - 0.015 14.5 0.8 0.051 12.7 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit cPLA2_C2 PF18695.1 PRP75260.1 - 0.063 13.3 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Cytosolic phospholipases A2 C2-domain SRP54 PF00448.22 PRP75260.1 - 0.07 12.8 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 PRP75260.1 - 0.073 13.0 0.4 1 9.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 PRP75260.1 - 0.088 13.2 1.3 1.2 9.5 1.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 PRP75260.1 - 0.095 12.5 1.2 1.8 8.2 0.6 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 PRP75260.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Lipase_3 PF01764.25 PRP75261.1 - 4.5e-25 88.2 0.0 3e-24 85.5 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 PRP75261.1 - 0.00022 20.8 0.1 0.0033 17.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 PRP75261.1 - 0.0062 17.2 0.1 0.017 15.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 PRP75261.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein SIS_2 PF13580.6 PRP75261.1 - 0.038 14.0 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 SIS domain LCAT PF02450.15 PRP75261.1 - 0.049 12.8 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 PRP75261.1 - 0.054 13.4 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP75261.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ABC_membrane_2 PF06472.15 PRP75262.1 - 5.1e-74 249.1 3.1 1.4e-72 244.3 3.1 2.2 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PRP75262.1 - 4.3e-17 62.9 0.0 1.7e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 PRP75262.1 - 0.00028 20.4 0.1 0.13 11.7 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PRP75262.1 - 0.0024 17.6 0.0 0.0081 15.9 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP75262.1 - 0.019 15.5 0.2 0.24 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PRP75262.1 - 0.024 15.0 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 PRP75262.1 - 0.025 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2089 PF09862.9 PRP75262.1 - 0.11 12.5 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) FBP_C PF16571.5 PRP75263.1 - 0.14 11.7 4.1 0.056 13.0 1.7 1.5 2 0 0 2 2 2 0 FBP C-terminal treble-clef zinc-finger FHA_2 PF17913.1 PRP75265.1 - 2.3e-11 43.8 0.0 5.3e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain FHA PF00498.26 PRP75265.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain RST PF12174.8 PRP75265.1 - 0.08 12.9 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Pkinase PF00069.25 PRP75266.1 - 8.5e-05 22.0 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_C PF00433.24 PRP75266.1 - 0.0057 17.3 0.2 0.011 16.4 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase PF00069.25 PRP75268.1 - 5.8e-27 94.7 0.0 1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75268.1 - 2.8e-12 46.5 0.0 4.8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75269.1 - 5.5e-74 248.9 0.0 1.4e-73 247.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75269.1 - 2.3e-34 118.9 0.0 3.5e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP75269.1 - 0.0003 20.2 0.0 0.00053 19.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GAS PF13851.6 PRP75269.1 - 0.035 13.5 0.4 0.06 12.7 0.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pkinase_fungal PF17667.1 PRP75269.1 - 0.048 12.4 0.2 0.11 11.3 0.2 1.6 1 1 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 PRP75269.1 - 0.051 12.6 0.0 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 SKA1 PF07160.12 PRP75269.1 - 0.16 11.8 2.6 0.28 11.0 2.6 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 2_5_RNA_ligase2 PF13563.6 PRP75271.1 - 2.1e-38 131.6 0.2 3.2e-38 131.0 0.2 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Sec7 PF01369.20 PRP75271.1 - 5.8e-33 114.1 0.0 1.6e-32 112.6 0.0 1.7 1 1 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 PRP75271.1 - 3.9e-05 23.5 0.7 0.00012 21.9 0.3 2.1 2 0 0 2 2 2 1 F-box-like LigT_PEase PF02834.16 PRP75271.1 - 0.0011 19.1 0.0 0.43 10.8 0.1 2.5 2 0 0 2 2 2 2 LigT like Phosphoesterase F-box PF00646.33 PRP75271.1 - 0.0026 17.6 0.1 0.0063 16.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain EF-hand_3 PF09069.11 PRP75271.1 - 0.048 14.1 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 EF-hand Cep3 PF16846.5 PRP75271.1 - 0.073 11.5 0.2 0.27 9.7 0.1 1.8 2 0 0 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit B HEAT_2 PF13646.6 PRP75272.1 - 2.1e-05 24.8 0.8 3.5e-05 24.1 0.2 1.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 PRP75272.1 - 0.0043 17.2 2.1 0.45 10.9 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat RGS PF00615.19 PRP75273.1 - 3.7e-14 53.0 5.9 2.6e-08 34.2 0.0 3.5 4 0 0 4 4 4 2 Regulator of G protein signaling domain SBF2 PF12335.8 PRP75273.1 - 5.4e-08 32.7 8.8 1.3e-07 31.5 0.2 3.3 2 1 1 3 3 3 1 Myotubularin protein Gluconate_2-dh3 PF13618.6 PRP75273.1 - 0.2 11.9 0.0 0.2 11.9 0.0 4.0 4 1 1 5 5 5 0 Gluconate 2-dehydrogenase subunit 3 DUF2730 PF10805.8 PRP75273.1 - 0.26 11.4 0.1 0.26 11.4 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) MCU PF04678.13 PRP75273.1 - 2.2 8.4 13.4 6.3 6.9 3.3 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter SUIM_assoc PF16619.5 PRP75273.1 - 4 7.6 8.3 21 5.3 6.0 3.3 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_2 PF07719.17 PRP75274.1 - 7.2e-30 100.7 20.2 0.00054 19.9 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 PRP75274.1 - 8.9e-27 91.8 22.2 2.8e-07 30.1 0.3 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 PRP75274.1 - 1e-22 78.4 14.5 0.0085 16.2 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 PRP75274.1 - 7.1e-19 66.9 14.5 0.046 14.6 0.0 9.1 3 1 6 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 PRP75274.1 - 2.5e-17 63.2 12.4 0.00012 22.6 0.3 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 PRP75274.1 - 1.2e-13 51.1 26.8 8.5e-06 26.0 1.6 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 PRP75274.1 - 3.1e-09 37.2 12.8 0.021 15.3 0.5 5.8 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP75274.1 - 1.2e-08 34.4 12.0 0.0032 17.1 0.1 5.7 2 1 3 5 5 5 2 TPR repeat TPR_17 PF13431.6 PRP75274.1 - 4.2e-08 33.0 22.6 0.0015 18.8 0.1 8.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP75274.1 - 2.7e-07 30.7 11.9 0.0016 18.5 1.2 4.5 2 1 4 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP75274.1 - 6.8e-07 29.4 16.7 0.08 13.2 3.5 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PRP75274.1 - 6.6e-06 26.4 15.8 6.8 7.5 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP75274.1 - 8.3e-06 25.5 19.0 0.23 11.6 0.1 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 PRP75274.1 - 0.00066 19.0 7.5 0.09 12.0 2.6 3.4 1 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 PRP75274.1 - 0.0072 15.3 0.9 0.035 13.0 0.3 2.3 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 PRP75274.1 - 0.015 15.1 18.4 3.2 7.8 1.5 7.4 7 1 1 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP75274.1 - 0.044 13.9 5.6 39 4.4 0.0 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 PRP75274.1 - 0.12 12.5 1.0 1.2 9.3 0.0 2.7 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 5 BTAD PF03704.17 PRP75274.1 - 0.27 11.6 6.7 1.8 9.0 0.5 3.7 4 1 0 4 4 3 0 Bacterial transcriptional activator domain F-box PF00646.33 PRP75275.1 - 0.0007 19.4 0.4 0.0021 17.9 0.4 1.8 1 0 0 1 1 1 1 F-box domain Ank_3 PF13606.6 PRP75275.1 - 0.0026 18.1 0.0 1.5e+02 3.5 0.0 6.2 6 0 0 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 PRP75275.1 - 0.012 16.2 0.5 27 5.5 0.0 5.5 7 1 1 8 8 8 0 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP75275.1 - 0.025 14.5 0.7 0.11 12.4 0.5 2.3 2 0 0 2 2 2 0 F-box-like F-box_4 PF15966.5 PRP75275.1 - 0.041 13.8 0.4 0.041 13.8 0.4 2.1 2 0 0 2 2 2 0 F-box Ank_2 PF12796.7 PRP75275.1 - 0.1 13.2 0.1 30 5.3 0.0 3.5 2 2 0 2 2 2 0 Ankyrin repeats (3 copies) NYD-SP28 PF14772.6 PRP75276.1 - 1.4e-15 57.2 14.5 1.4e-15 57.2 14.5 5.5 3 2 2 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 PRP75276.1 - 4.3e-07 29.9 1.3 4.3e-07 29.9 1.3 4.5 4 1 0 4 4 4 1 Sperm tail C-terminal domain DUF5082 PF16888.5 PRP75276.1 - 0.00051 20.3 11.1 0.00051 20.3 11.1 4.4 1 1 3 4 4 4 1 Domain of unknown function (DUF5082) HALZ PF02183.18 PRP75276.1 - 2.6 8.3 17.8 4.7 7.5 1.4 5.2 5 0 0 5 5 5 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 PRP75276.1 - 6.5 6.8 16.5 1.3 9.0 3.2 3.7 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CPL PF08144.11 PRP75277.1 - 3.8e-19 69.4 0.3 2.4e-16 60.4 0.0 4.2 2 2 1 3 3 3 1 CPL (NUC119) domain PUF PF00806.19 PRP75277.1 - 4.2e-05 23.0 0.2 0.064 13.0 0.0 3.3 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat DUF4279 PF14106.6 PRP75277.1 - 0.24 11.6 1.7 0.36 11.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) PUF PF00806.19 PRP75278.1 - 1.9e-05 24.1 0.0 3.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat Adaptin_N PF01602.20 PRP75279.1 - 0.012 14.2 0.1 0.017 13.7 0.1 1.2 1 0 0 1 1 1 0 Adaptin N terminal region HEAT_2 PF13646.6 PRP75279.1 - 0.033 14.6 0.1 0.12 12.8 0.1 2.0 1 0 0 1 1 1 0 HEAT repeats Cnd1 PF12717.7 PRP75279.1 - 0.039 14.0 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP75279.1 - 0.043 14.1 7.1 0.17 12.2 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 PRP75279.1 - 0.25 11.9 3.3 5.3 7.7 0.0 3.6 2 1 2 4 4 4 0 HEAT-like repeat Cnd1 PF12717.7 PRP75280.1 - 1.8e-28 99.6 17.2 1.2e-25 90.5 1.4 6.1 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP75280.1 - 1e-05 25.4 14.8 1.5 9.3 0.1 8.1 9 0 0 9 9 9 3 HEAT repeat Adaptin_N PF01602.20 PRP75280.1 - 0.00085 18.0 0.7 0.00085 18.0 0.7 4.7 2 2 2 4 4 4 1 Adaptin N terminal region Cnd3 PF12719.7 PRP75280.1 - 0.004 16.4 0.1 0.004 16.4 0.1 3.5 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain Cyclin_C_2 PF16899.5 PRP75280.1 - 0.23 11.9 0.8 2.2 8.7 0.3 3.0 2 0 0 2 2 2 0 Cyclin C-terminal domain TFCD_C PF12612.8 PRP75280.1 - 0.32 10.8 3.4 1.9 8.3 0.2 3.9 5 1 0 5 5 5 0 Tubulin folding cofactor D C terminal UCH PF00443.29 PRP75282.1 - 2.3e-45 155.1 1.3 5.9e-45 153.8 1.3 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP75282.1 - 1.3e-16 61.1 3.4 8.6e-15 55.1 3.4 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PRP75282.1 - 7.8e-13 48.9 16.0 2.7e-05 24.7 0.1 5.6 5 1 0 5 5 5 3 DUSP domain ubiquitin PF00240.23 PRP75282.1 - 1.1e-11 44.3 0.3 3.4e-11 42.7 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin family DUF2757 PF10955.8 PRP75282.1 - 0.017 15.4 3.3 0.33 11.3 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) TBK1_ULD PF18396.1 PRP75282.1 - 0.13 12.2 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP75282.1 - 0.76 10.2 6.0 20 5.6 1.0 3.4 3 0 0 3 3 3 0 Ubiquitin-like domain Ank_2 PF12796.7 PRP75284.1 - 1.3e-69 230.8 14.1 1.6e-14 54.2 0.0 6.9 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75284.1 - 1e-67 223.7 14.9 5.4e-11 42.8 0.1 10.6 3 2 9 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 PRP75284.1 - 3.9e-47 156.7 8.4 1.9e-06 28.0 0.3 12.5 11 2 0 11 11 11 8 Ankyrin repeat Ank_3 PF13606.6 PRP75284.1 - 3.5e-46 149.8 0.2 9.6e-05 22.5 0.0 13.1 14 0 0 14 14 14 7 Ankyrin repeat Ank_5 PF13857.6 PRP75284.1 - 1.2e-42 143.3 2.2 1e-07 32.1 0.0 8.8 5 2 4 9 9 9 8 Ankyrin repeats (many copies) VWA_3_C PF18571.1 PRP75284.1 - 0.00033 20.4 9.8 8.4 6.4 0.0 6.6 7 0 0 7 7 7 1 von Willebrand factor type A C-terminal domain DUF3718 PF12514.8 PRP75284.1 - 0.13 12.4 1.5 33 4.7 0.2 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF3718) Ank_2 PF12796.7 PRP75285.1 - 0.0033 18.0 0.0 0.0095 16.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75285.1 - 0.14 12.8 0.0 1.1 9.9 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) NUDIX PF00293.28 PRP75286.1 - 1.1e-05 25.5 5.7 1.3e-05 25.2 3.2 2.3 2 1 0 2 2 2 1 NUDIX domain RED_N PF07808.13 PRP75288.1 - 0.0016 18.0 0.1 0.0029 17.2 0.0 1.5 1 1 1 2 2 2 1 RED-like protein N-terminal region Ank_2 PF12796.7 PRP75289.1 - 2e-34 118.0 0.1 1.1e-10 41.9 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PRP75289.1 - 6.4e-25 86.5 2.3 0.0011 19.4 0.0 7.6 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 PRP75289.1 - 7.5e-25 87.0 2.3 9e-08 32.5 0.1 5.0 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP75289.1 - 4.2e-24 84.3 0.7 2.4e-06 27.7 0.0 5.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75289.1 - 2.1e-23 79.8 0.2 0.011 16.2 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Cullin PF00888.22 PRP75290.1 - 7.5e-211 702.0 18.8 8.4e-211 701.8 18.8 1.0 1 0 0 1 1 1 1 Cullin family PIN_8 PF18476.1 PRP75290.1 - 2.3 8.0 5.8 0.35 10.7 0.5 2.3 3 0 0 3 3 3 0 PIN like domain Chlorophyllase PF07224.11 PRP75293.1 - 0.026 13.5 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase SIT PF15330.6 PRP75295.1 - 1.6 9.2 7.3 17 5.9 2.6 2.1 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Ank_2 PF12796.7 PRP75298.1 - 0.027 15.1 0.0 0.27 11.9 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) Amidohydro_1 PF01979.20 PRP75298.1 - 0.18 11.1 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family PARP PF00644.20 PRP75300.1 - 2.3e-17 63.2 0.0 5e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain MtrH PF02007.18 PRP75302.1 - 0.087 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Methyltransf_32 PF13679.6 PRP75303.1 - 1.5e-18 67.3 0.4 3.8e-10 40.0 0.5 3.5 3 1 0 3 3 3 2 Methyltransferase domain RasGAP PF00616.19 PRP75303.1 - 1.6e-18 67.2 0.6 1.9e-14 53.8 1.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase AhpC-TSA PF00578.21 PRP75303.1 - 7.1e-13 48.6 0.0 1.9e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family AviRa PF11599.8 PRP75303.1 - 2.5e-07 30.4 0.0 0.011 15.2 0.0 2.7 3 0 0 3 3 3 2 RRNA methyltransferase AviRa MTS PF05175.14 PRP75303.1 - 1e-06 28.4 0.0 0.002 17.7 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 PRP75303.1 - 1.9e-05 24.5 0.1 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP75303.1 - 0.00016 22.3 0.0 0.0045 17.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP75303.1 - 0.0019 18.0 0.0 0.18 11.7 0.0 3.1 3 1 1 4 4 4 1 Methyltransferase domain YscJ_FliF PF01514.17 PRP75303.1 - 0.0025 17.5 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 2 Secretory protein of YscJ/FliF family Cons_hypoth95 PF03602.15 PRP75303.1 - 0.0028 17.3 0.0 0.074 12.7 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 NAD_binding_8 PF13450.6 PRP75303.1 - 0.033 14.4 0.0 1.9 8.8 0.0 2.8 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Redoxin PF08534.10 PRP75303.1 - 0.044 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Redoxin TRM13 PF05206.14 PRP75303.1 - 0.054 13.0 0.1 11 5.5 0.0 3.1 2 1 1 3 3 3 0 Methyltransferase TRM13 Beta_helix PF13229.6 PRP75304.1 - 0.016 15.1 2.7 0.091 12.6 2.7 2.4 1 1 0 1 1 1 0 Right handed beta helix region DUF1084 PF06454.11 PRP75305.1 - 1.3e-11 44.4 12.5 2.3e-11 43.6 12.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF1345 PF07077.11 PRP75305.1 - 0.00066 19.4 3.1 0.28 10.9 1.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1345) PMD PF10536.9 PRP75305.1 - 0.14 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Plant mobile domain Phtf-FEM1B_bdg PF12129.8 PRP75305.1 - 6.1 6.7 9.1 0.29 11.0 0.3 2.9 1 1 2 4 4 4 0 Male germ-cell putative homeodomain transcription factor Pkinase_Tyr PF07714.17 PRP75306.1 - 1.7e-79 266.8 0.0 3.3e-79 265.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75306.1 - 1.8e-48 165.2 0.0 1.1e-47 162.6 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 PRP75306.1 - 8.8e-24 83.0 35.8 1.2e-08 34.6 9.6 4.8 4 0 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PRP75306.1 - 4.4e-14 52.4 36.2 0.0014 19.0 0.6 6.3 3 2 1 5 5 5 5 Leucine Rich repeats (2 copies) CPBP PF02517.16 PRP75306.1 - 4.5e-13 49.4 14.7 5.5e-13 49.1 12.5 2.4 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease PI3K_rbd PF00794.18 PRP75306.1 - 8e-05 22.8 0.0 0.00026 21.1 0.0 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain LRR_1 PF00560.33 PRP75306.1 - 0.00069 19.8 36.8 9.7 7.2 0.6 9.8 8 1 1 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP75306.1 - 0.0026 17.7 35.6 1.8 8.8 2.2 9.2 9 0 0 9 9 9 2 Leucine Rich repeat Pkinase_fungal PF17667.1 PRP75306.1 - 0.02 13.7 0.0 0.041 12.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase TetR_C_22 PF17928.1 PRP75306.1 - 0.021 15.1 0.2 0.086 13.2 0.2 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MSA-2c PF12238.8 PRP75306.1 - 0.034 14.1 1.7 0.16 12.0 1.7 2.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Occludin_ELL PF07303.13 PRP75306.1 - 0.51 11.1 4.7 2.6 8.8 0.7 3.4 2 0 0 2 2 2 0 Occludin homology domain Topoisom_bac PF01131.20 PRP75307.1 - 3.5e-106 355.7 0.0 4.5e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 PRP75307.1 - 2.6e-13 50.1 0.0 4.5e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Cript PF10235.9 PRP75307.1 - 0.015 15.9 2.4 0.037 14.6 0.1 2.5 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT PAT1 PF09770.9 PRP75308.1 - 3.2e-12 45.6 0.0 3.2e-12 45.6 0.0 6.5 4 2 1 5 5 5 3 Topoisomerase II-associated protein PAT1 Pkinase_Tyr PF07714.17 PRP75309.1 - 2.1e-48 164.9 0.0 2e-39 135.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PRP75309.1 - 2e-43 145.6 102.0 0.00064 20.1 4.9 19.0 15 4 2 19 19 19 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP75309.1 - 2e-35 120.4 110.9 5.6e-07 29.2 2.1 17.9 9 4 9 20 20 20 16 Leucine rich repeat Pkinase PF00069.25 PRP75309.1 - 2.5e-33 115.6 0.0 2.3e-31 109.1 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain LRR_6 PF13516.6 PRP75309.1 - 2.1e-20 71.0 84.9 0.22 11.7 0.1 27.1 30 0 0 30 30 30 6 Leucine Rich repeat LRR_1 PF00560.33 PRP75309.1 - 4e-12 44.9 78.3 0.68 10.7 0.0 26.3 25 4 0 25 25 25 3 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP75309.1 - 0.00015 21.9 1.1 0.00039 20.7 1.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Kdo PF06293.14 PRP75309.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syndecan PF01034.20 PRP75309.1 - 0.035 14.0 0.2 0.077 12.9 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain DUF5612 PF18462.1 PRP75309.1 - 0.04 13.7 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) Peptidase_C1 PF00112.23 PRP75310.1 - 1.2e-36 126.9 3.9 2.6e-36 125.7 3.9 1.6 1 0 0 1 1 1 1 Papain family cysteine protease PAN_4 PF14295.6 PRP75310.1 - 6.2e-06 26.0 6.4 6.2e-06 26.0 6.4 2.8 3 0 0 3 3 3 1 PAN domain Peptidase_C1_2 PF03051.15 PRP75310.1 - 0.0001 21.2 1.3 0.0048 15.7 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family PAN_1 PF00024.26 PRP75310.1 - 0.029 14.4 0.6 0.079 12.9 0.6 1.7 1 0 0 1 1 1 0 PAN domain DNA_pol_A PF00476.20 PRP75311.1 - 5.2e-106 354.9 0.0 9.2e-106 354.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 PRP75311.1 - 0.0026 17.5 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease SEN1_N PF12726.7 PRP75312.1 - 0.075 11.2 1.4 0.18 10.0 0.5 1.9 2 0 0 2 2 2 0 SEN1 N terminal GST_N_3 PF13417.6 PRP75313.1 - 3.3e-31 107.5 0.2 5.7e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP75313.1 - 1.8e-18 66.6 0.0 3.2e-10 40.1 0.0 2.6 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PRP75313.1 - 1.2e-13 51.2 0.0 1.7e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PRP75313.1 - 2.8e-13 49.9 0.1 6.9e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Glutaredoxin DUF836 PF05768.14 PRP75313.1 - 0.0012 19.2 0.1 0.099 13.1 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 PRP75313.1 - 0.021 15.3 0.2 2.4 8.7 0.1 2.6 2 1 1 3 3 3 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 PRP75313.1 - 0.18 11.9 0.3 1.4 9.0 0.0 2.4 2 1 1 3 3 3 0 Thioredoxin domain Peptidase_C1 PF00112.23 PRP75315.1 - 9.2e-34 117.4 5.0 1.8e-28 100.1 5.0 2.6 1 1 0 1 1 1 1 Papain family cysteine protease UQ_con PF00179.26 PRP75315.1 - 5.7e-10 39.0 0.0 2.2e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Inhibitor_I29 PF08246.12 PRP75315.1 - 2.3e-06 28.0 2.2 5.7e-06 26.7 2.2 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP75315.1 - 0.00012 21.0 1.5 0.0071 15.2 0.1 2.7 3 0 0 3 3 3 1 Peptidase C1-like family PAN_4 PF14295.6 PRP75315.1 - 0.0022 17.9 6.1 0.0022 17.9 6.1 2.3 3 0 0 3 3 3 1 PAN domain RWD PF05773.22 PRP75315.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 RWD domain PH_2 PF08458.10 PRP75315.1 - 0.016 15.5 0.2 0.047 14.0 0.2 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PAN_1 PF00024.26 PRP75315.1 - 0.035 14.1 1.4 0.091 12.7 1.4 1.6 1 0 0 1 1 1 0 PAN domain Prok-E2_B PF14461.6 PRP75315.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B D5_N PF08706.11 PRP75315.1 - 2.1 8.6 6.0 4.6 7.5 1.8 3.0 3 0 0 3 3 3 0 D5 N terminal like Pectate_lyase_3 PF12708.7 PRP75316.1 - 4.1e-98 327.5 17.3 2.4e-83 279.2 8.0 3.3 3 1 0 3 3 3 2 Pectate lyase superfamily protein Carb_bind PF10645.9 PRP75316.1 - 8.5e-09 35.5 63.2 0.0056 16.9 4.0 6.0 5 1 1 6 6 6 4 Carbohydrate binding End_N_terminal PF12218.8 PRP75316.1 - 1.6e-08 34.1 1.2 0.0025 17.5 0.0 3.0 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 PRP75316.1 - 0.0019 18.1 4.0 0.0075 16.1 4.0 2.1 1 0 0 1 1 1 1 Right handed beta helix region IGFL PF14653.6 PRP75316.1 - 0.066 13.2 25.9 0.076 13.0 3.2 4.5 5 0 0 5 5 5 0 Insulin growth factor-like family Pkinase PF00069.25 PRP75317.1 - 2.3e-76 256.7 0.0 2.8e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75317.1 - 5.7e-37 127.4 0.0 7.4e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP75317.1 - 1.6e-07 31.0 0.1 6.5e-06 25.7 0.0 2.3 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 PRP75317.1 - 0.0006 19.5 0.2 0.84 9.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PRP75317.1 - 0.0017 17.2 0.1 0.0038 16.0 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP75317.1 - 0.0017 17.7 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP75317.1 - 0.0026 16.8 0.0 0.0026 16.8 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain YukC PF10140.9 PRP75317.1 - 0.015 14.2 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pkinase_C PF00433.24 PRP75317.1 - 0.016 15.9 0.2 0.042 14.6 0.2 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 PRP75317.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 PRP75318.1 - 1.8e-67 227.5 0.0 2.3e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75318.1 - 1.4e-31 109.8 0.0 1.9e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP75318.1 - 0.00012 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP75318.1 - 0.0016 17.5 0.2 0.0023 17.0 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PRP75318.1 - 0.041 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 PRP75318.1 - 0.055 12.2 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase 2_5_RNA_ligase2 PF13563.6 PRP75320.1 - 2.3e-39 134.7 0.2 2.7e-39 134.5 0.2 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 PRP75320.1 - 5.2e-05 23.4 0.0 0.076 13.2 0.1 2.3 2 0 0 2 2 2 2 LigT like Phosphoesterase CPDase PF07823.11 PRP75320.1 - 0.0074 16.0 0.1 1.1 8.9 0.0 2.1 1 1 1 2 2 2 2 Cyclic phosphodiesterase-like protein Laminin_G_3 PF13385.6 PRP75321.1 - 1.1e-21 77.6 0.0 2.4e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sec7 PF01369.20 PRP75322.1 - 2.9e-33 115.1 0.0 8.5e-33 113.6 0.0 1.7 1 1 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 PRP75322.1 - 2.5e-05 24.1 0.7 8.4e-05 22.4 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP75322.1 - 0.0016 18.2 0.1 0.0044 16.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain EF-hand_3 PF09069.11 PRP75322.1 - 0.031 14.7 0.0 0.097 13.1 0.0 1.8 2 0 0 2 2 2 0 EF-hand Cep3 PF16846.5 PRP75322.1 - 0.041 12.4 0.2 0.18 10.2 0.1 1.9 2 0 0 2 2 2 0 Centromere DNA-binding protein complex CBF3 subunit B HEAT_2 PF13646.6 PRP75323.1 - 1.8e-05 25.1 0.8 2.9e-05 24.4 0.2 1.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 PRP75323.1 - 0.0034 17.5 2.2 0.4 11.1 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat DUF4278 PF14105.6 PRP75324.1 - 0.1 13.0 0.1 10 6.7 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4278) Calici_PP_N PF08405.11 PRP75324.1 - 0.7 8.6 6.2 2.8 6.7 0.8 2.2 1 1 1 2 2 2 0 Viral polyprotein N-terminal H_PPase PF03030.16 PRP75325.1 - 4.8e-51 174.2 46.1 3.6e-39 134.9 23.7 2.9 2 1 1 3 3 3 2 Inorganic H+ pyrophosphatase Pkinase_Tyr PF07714.17 PRP75326.1 - 2.3e-31 109.1 0.0 5e-31 107.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75326.1 - 7.6e-25 87.8 0.0 1.3e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP75326.1 - 5.3e-09 36.5 5.8 1.5e-08 35.0 5.8 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_8 PF13855.6 PRP75326.1 - 4.9e-08 32.6 12.5 0.079 12.7 0.0 7.0 7 1 0 7 7 7 3 Leucine rich repeat FAM176 PF14851.6 PRP75326.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family LRR_4 PF12799.7 PRP75326.1 - 0.16 12.4 39.2 0.55 10.7 0.1 9.3 7 3 1 9 9 9 0 Leucine Rich repeats (2 copies) Homeodomain PF00046.29 PRP75328.1 - 1.9e-10 40.4 11.4 7.4e-05 22.5 0.0 3.8 3 1 0 3 3 3 2 Homeodomain hDGE_amylase PF14701.6 PRP75329.1 - 6.7e-140 467.0 0.0 1.6e-139 465.8 0.0 1.6 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 PRP75329.1 - 1.3e-117 393.0 0.1 2e-117 392.4 0.1 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 PRP75329.1 - 1.9e-64 217.7 0.0 3.8e-64 216.8 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 PRP75329.1 - 9.2e-11 41.7 0.0 2.1e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Dynamin_N PF00350.23 PRP75334.1 - 1e-13 51.7 0.8 2.7e-13 50.3 0.2 2.1 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 PRP75334.1 - 0.0016 17.7 0.1 0.0048 16.2 0.1 1.8 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 PRP75334.1 - 0.12 12.5 0.7 0.6 10.2 0.7 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 PRP75334.1 - 0.87 10.1 7.0 1.7 9.1 4.5 2.7 2 1 0 2 2 2 0 AAA domain Dabb PF07876.12 PRP75335.1 - 3.4e-14 53.2 0.5 1.2e-05 25.9 0.0 2.5 2 0 0 2 2 2 2 Stress responsive A/B Barrel Domain Peptidase_S29 PF02907.15 PRP75335.1 - 0.036 13.8 0.7 0.095 12.4 0.2 1.8 1 1 1 2 2 2 0 Hepatitis C virus NS3 protease CHORD PF04968.12 PRP75335.1 - 0.042 14.6 1.7 0.43 11.3 0.3 2.7 2 0 0 2 2 2 0 CHORD adh_short PF00106.25 PRP75336.1 - 2.7e-21 75.9 0.2 3.6e-11 42.9 0.1 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP75336.1 - 2.7e-12 46.7 0.3 2.5e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP75336.1 - 0.002 18.1 0.1 0.005 16.8 0.1 1.6 1 0 0 1 1 1 1 KR domain Kp4 PF09044.10 PRP75338.1 - 6.3e-24 84.4 0.6 2.8e-23 82.3 0.6 1.8 1 1 0 1 1 1 1 Kp4 MU117 PF15474.6 PRP75338.1 - 0.022 15.6 0.0 0.059 14.2 0.0 1.7 1 1 0 1 1 1 0 Meiotically up-regulated gene family TIG PF01833.24 PRP75339.1 - 4.4e-42 142.1 194.8 4.1e-09 36.4 8.0 19.6 18 3 3 21 21 21 13 IPT/TIG domain Pkinase_Tyr PF07714.17 PRP75339.1 - 4.9e-28 98.1 0.0 9.8e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75339.1 - 1.3e-23 83.7 0.0 2.9e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Metallophos PF00149.28 PRP75339.1 - 1e-16 62.1 0.1 2e-16 61.1 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GPS PF01825.21 PRP75339.1 - 5.1e-09 36.5 8.2 1.4e-08 35.1 8.2 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif GLEYA PF10528.9 PRP75339.1 - 0.073 13.5 0.6 0.39 11.2 0.1 2.6 2 0 0 2 2 2 0 GLEYA domain ARL2_Bind_BART PF11527.8 PRP75340.1 - 0.099 12.7 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Tlr3_TMD PF17968.1 PRP75341.1 - 0.75 10.0 6.7 2.5 8.4 2.3 3.3 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain RSN1_7TM PF02714.15 PRP75342.1 - 6.5e-36 124.0 21.4 1.3e-35 123.1 21.4 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 PRP75342.1 - 1.7e-16 60.9 0.0 2.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 PRP75342.1 - 2.9e-14 53.1 5.9 2.9e-14 53.1 5.9 3.3 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport CCSMST1 PF15013.6 PRP75342.1 - 1.2 9.4 6.6 7.9 6.7 0.4 3.5 3 0 0 3 3 3 0 CCSMST1 family Mito_fiss_reg PF05308.11 PRP75343.1 - 0.8 9.7 7.2 7 6.7 6.9 2.5 1 1 0 1 1 1 0 Mitochondrial fission regulator START PF01852.19 PRP75344.1 - 0.0011 18.4 1.1 0.0018 17.7 0.0 1.8 2 0 0 2 2 2 1 START domain MIP-T3 PF10243.9 PRP75344.1 - 0.19 11.7 0.9 0.89 9.6 0.0 2.4 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 CH-like domain START PF01852.19 PRP75345.1 - 0.0066 15.9 2.1 0.0088 15.5 0.1 2.0 2 0 0 2 2 2 1 START domain SNARE_assoc PF09335.11 PRP75346.1 - 2.1e-18 66.9 7.6 2.1e-18 66.9 7.6 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein Sec20 PF03908.13 PRP75347.1 - 5.2e-19 68.0 0.9 5.2e-19 68.0 0.9 2.9 2 1 2 4 4 4 1 Sec20 YrbL-PhoP_reg PF10707.9 PRP75347.1 - 0.014 15.0 0.6 0.03 13.9 0.6 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MRP-S26 PF14943.6 PRP75347.1 - 0.032 14.1 16.1 3.2 7.6 16.1 2.2 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4559 PF15112.6 PRP75347.1 - 0.54 9.9 7.1 0.75 9.4 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) SKA2 PF16740.5 PRP75347.1 - 0.57 10.0 15.7 1.7 8.5 7.8 2.4 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF572 PF04502.13 PRP75347.1 - 1.5 8.3 10.1 2.1 7.9 10.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mrpl_C PF18502.1 PRP75347.1 - 1.7 8.9 9.8 4.5 7.6 4.1 2.3 1 1 1 2 2 2 0 54S ribosomal protein L8 C-terminal domain ALMT PF11744.8 PRP75347.1 - 7.8 5.2 10.0 9.8 4.9 10.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4200 PF13863.6 PRP75347.1 - 8.6 6.8 24.7 0.43 11.0 2.5 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF2518 PF10726.9 PRP75348.1 - 0.18 11.5 1.8 3.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) FIT1_2 PF17357.2 PRP75348.1 - 0.19 11.8 0.2 0.19 11.8 0.2 2.5 2 1 1 3 3 3 0 Facilitor Of iron transport 1 and 2 HAD PF12710.7 PRP75349.1 - 4.2e-18 66.4 0.0 7.4e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP75349.1 - 5.1e-13 49.8 0.7 3.8e-12 46.9 0.5 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PRP75349.1 - 8.6e-11 42.0 0.3 1.5e-07 31.4 0.0 3.3 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PRP75349.1 - 3.1e-06 27.4 0.0 1.4e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 PRP75349.1 - 3.8e-05 23.2 0.0 0.00014 21.3 0.0 1.8 2 0 0 2 2 2 1 Putative Phosphatase HTH_26 PF13443.6 PRP75349.1 - 0.0043 17.4 0.0 0.056 13.9 0.0 2.5 2 0 0 2 2 2 1 Cro/C1-type HTH DNA-binding domain Sulfatase PF00884.23 PRP75349.1 - 0.027 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Sulfatase S6PP PF05116.13 PRP75349.1 - 0.13 11.8 0.3 0.63 9.5 0.0 2.2 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase DBB PF14545.6 PRP75349.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, CLU PF13236.6 PRP75350.1 - 4.2e-37 128.1 0.0 1.1e-36 126.7 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria LRR_4 PF12799.7 PRP75350.1 - 9.5e-11 41.8 26.0 0.045 14.2 0.9 10.4 6 3 5 11 11 11 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP75350.1 - 0.00036 20.3 19.4 0.13 12.4 0.0 9.8 11 0 0 11 11 11 1 Leucine Rich repeat eIF3_p135 PF12807.7 PRP75350.1 - 0.00047 20.2 0.7 0.0038 17.3 0.1 2.4 1 1 1 2 2 2 1 Translation initiation factor eIF3 subunit 135 DUF1699 PF08004.11 PRP75350.1 - 0.21 11.3 3.8 7.7 6.2 0.1 4.7 5 1 0 6 6 6 0 Protein of unknown function (DUF1699) LRR_8 PF13855.6 PRP75350.1 - 0.85 9.4 15.3 15 5.5 0.6 6.7 5 2 3 8 8 8 0 Leucine rich repeat Glyco_hydro_71 PF03659.14 PRP75351.1 - 1.8e-89 300.2 3.0 1.8e-89 300.2 3.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 PH PF00169.29 PRP75351.1 - 1.4e-05 25.5 0.1 1.4e-05 25.5 0.1 3.7 4 0 0 4 4 4 1 PH domain PH_8 PF15409.6 PRP75351.1 - 2.4e-05 24.5 0.1 0.00011 22.4 0.1 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain Clp_N PF02861.20 PRP75351.1 - 0.0094 16.1 7.7 45 4.3 0.1 6.3 6 0 0 6 6 6 1 Clp amino terminal domain, pathogenicity island component Kp4 PF09044.10 PRP75353.1 - 1.3e-23 83.5 1.5 4.8e-23 81.6 1.5 1.8 1 1 0 1 1 1 1 Kp4 Mucin15 PF15672.5 PRP75353.1 - 0.035 13.6 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 DUF4512 PF14975.6 PRP75356.1 - 2.9 8.7 7.4 1.3 9.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) EPSP_synthase PF00275.20 PRP75357.1 - 1.6e-119 399.4 0.0 2.4e-119 398.7 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 PRP75357.1 - 4.5e-98 327.6 0.0 7.9e-98 326.8 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 PRP75357.1 - 4.9e-46 157.8 0.0 1e-45 156.8 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 PRP75357.1 - 1.1e-31 110.0 0.0 3.3e-29 102.1 0.0 3.0 4 0 0 4 4 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 PRP75357.1 - 1.3e-25 89.4 0.0 3.1e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 PRP75357.1 - 1.5e-08 34.6 0.1 6.6e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 PRP75357.1 - 2.1e-05 24.2 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 PRP75357.1 - 0.00034 20.7 0.0 0.00074 19.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 PRP75357.1 - 0.002 17.0 1.3 0.0051 15.7 0.1 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase NAD_binding_2 PF03446.15 PRP75357.1 - 0.0042 17.3 1.6 0.074 13.2 0.0 2.9 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase AAA_33 PF13671.6 PRP75357.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PRP75357.1 - 0.03 14.7 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ApbA PF02558.16 PRP75357.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AAA_18 PF13238.6 PRP75357.1 - 0.09 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PRP75357.1 - 0.12 12.9 0.0 0.44 11.1 0.0 1.9 2 0 0 2 2 1 0 ABC transporter Glyco_hydro_72 PF03198.14 PRP75358.1 - 1.6e-115 385.7 11.7 6.3e-101 337.8 8.7 2.2 2 0 0 2 2 2 2 Glucanosyltransferase X8 PF07983.13 PRP75358.1 - 1.7e-09 38.2 6.8 1.7e-09 38.2 6.8 2.1 2 0 0 2 2 2 1 X8 domain DUF4336 PF14234.6 PRP75358.1 - 0.0002 20.7 0.1 0.16 11.1 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4336) Glyco_hydro_2_C PF02836.17 PRP75358.1 - 0.00067 18.9 0.2 0.0022 17.2 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain LolA_2 PF16584.5 PRP75358.1 - 0.017 15.0 0.1 3.6 7.5 0.0 3.0 3 0 0 3 3 3 0 Outer membrane lipoprotein carrier protein LolA Cellulase PF00150.18 PRP75358.1 - 0.044 13.2 0.9 0.23 10.8 0.9 2.0 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Peptidase_S8 PF00082.22 PRP75361.1 - 1.7e-39 135.9 8.5 3.3e-39 134.9 8.5 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 PRP75361.1 - 3e-07 31.0 2.0 5.9e-07 30.1 2.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 TPD PF14811.6 PRP75361.1 - 0.014 15.2 0.1 0.026 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif Ank_2 PF12796.7 PRP75362.1 - 2.3e-17 63.3 0.0 5.5e-11 42.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP75362.1 - 4e-12 46.1 0.0 3.3e-05 24.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP75362.1 - 6.7e-11 42.5 0.0 0.00028 21.4 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75362.1 - 1.4e-08 34.3 0.0 0.0017 18.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PRP75362.1 - 2e-08 34.3 0.0 0.00065 20.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.25 PRP75363.1 - 2.6e-05 23.7 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain X8 PF07983.13 PRP75364.1 - 2.2e-12 47.5 8.5 2.2e-12 47.5 8.5 2.5 2 1 0 2 2 2 1 X8 domain Collagen PF01391.18 PRP75364.1 - 9.6e-06 25.3 21.4 9.6e-06 25.3 21.4 2.3 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) RWD PF05773.22 PRP75365.1 - 8.2e-18 64.8 1.0 1.7e-17 63.7 0.1 2.1 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 PRP75365.1 - 4.7e-08 33.4 3.5 1.1e-07 32.3 3.5 1.6 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Semialdhyde_dhC PF02774.18 PRP75366.1 - 1.3e-38 133.0 0.0 1.6e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 PRP75366.1 - 4.5e-32 111.0 0.0 7.4e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 PRP75366.1 - 2e-05 24.2 0.2 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 2 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DXP_reductoisom PF02670.16 PRP75366.1 - 0.0044 17.7 0.1 0.015 16.0 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 PRP75366.1 - 0.0092 16.1 0.0 0.033 14.3 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Ank_3 PF13606.6 PRP75368.1 - 0.0029 18.0 0.0 7.7 7.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PRP75368.1 - 0.041 14.5 0.0 0.21 12.2 0.0 2.1 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ribosomal_L22 PF00237.19 PRP75369.1 - 1e-21 77.1 1.0 1e-21 77.1 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e NosD PF05048.13 PRP75370.1 - 0.18 11.0 37.6 0.094 12.0 8.8 4.6 1 1 3 4 4 4 0 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 PRP75370.1 - 0.99 10.0 0.0 0.99 10.0 0.0 8.8 8 3 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat P2X_receptor PF00864.19 PRP75371.1 - 5.1e-15 55.4 1.5 3.9e-07 29.5 0.1 2.2 2 0 0 2 2 2 2 ATP P2X receptor Actin PF00022.19 PRP75374.1 - 1.9e-22 79.4 0.0 2.1e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Actin Voltage_CLC PF00654.20 PRP75375.1 - 6.4e-51 173.7 13.2 6.4e-51 173.7 13.2 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel Pkinase_Tyr PF07714.17 PRP75376.1 - 1.2e-48 165.6 0.1 2e-48 165.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75376.1 - 4.3e-36 124.6 0.3 7.4e-36 123.9 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP75376.1 - 3.2e-07 30.8 3.8 1.1e-06 29.0 3.8 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP75376.1 - 0.0021 17.4 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Insulin_TMD PF17870.1 PRP75376.1 - 0.034 14.2 0.8 0.081 13.0 0.8 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Kdo PF06293.14 PRP75376.1 - 0.12 11.7 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP75376.1 - 0.34 9.6 0.0 0.34 9.6 0.0 3.6 3 1 0 3 3 3 0 Fungal protein kinase SKG6 PF08693.10 PRP75376.1 - 6.7 6.2 7.1 36 3.9 7.1 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3235 PF11574.8 PRP75376.1 - 8.1 7.4 6.9 3.6 8.5 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Pkinase_Tyr PF07714.17 PRP75377.1 - 2.5e-49 167.9 0.0 3.5e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75377.1 - 4.1e-37 128.0 0.1 6.4e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP75377.1 - 1.2e-08 35.3 3.9 2.8e-08 34.1 3.9 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kdo PF06293.14 PRP75377.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP75377.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 PRP75377.1 - 0.05 13.2 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 PRP75377.1 - 0.74 8.5 3.2 7.2 5.3 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase VirE PF05272.11 PRP75381.1 - 3.7e-05 23.6 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Virulence-associated protein E DUF2207 PF09972.9 PRP75381.1 - 8.6 5.0 9.0 1.4 7.6 0.3 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF5614 PF18474.1 PRP75383.1 - 0.00022 20.6 0.3 0.0057 16.0 0.0 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5614) ESR1_C PF12743.7 PRP75383.1 - 0.52 10.1 2.5 8.3 6.3 0.3 2.6 1 1 1 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal DUF5614 PF18474.1 PRP75386.1 - 2.1e-06 27.2 1.4 0.1 11.9 0.1 3.0 1 1 2 3 3 3 3 Family of unknown function (DUF5614) HTH_Tnp_Tc3_2 PF01498.18 PRP75386.1 - 0.011 15.9 0.2 18 5.6 0.0 3.0 3 0 0 3 3 3 0 Transposase ESR1_C PF12743.7 PRP75386.1 - 0.029 14.2 12.1 2.2 8.2 0.3 3.5 1 1 2 3 3 3 0 Oestrogen-type nuclear receptor final C-terminal Bac_DnaA_C PF08299.11 PRP75386.1 - 0.84 9.7 7.1 5.3 7.2 0.4 2.5 1 1 2 3 3 3 0 Bacterial dnaA protein helix-turn-helix E1-E2_ATPase PF00122.20 PRP75387.1 - 3.5e-23 82.1 0.0 7.7e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 PRP75387.1 - 1.5e-09 38.4 0.0 0.0012 19.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP75387.1 - 1.1e-06 28.7 0.0 2.8e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP75387.1 - 0.0021 17.8 0.1 0.054 13.2 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FAD_binding_7 PF03441.14 PRP75388.1 - 2.7e-74 249.0 3.3 6.2e-74 247.9 2.9 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PRP75388.1 - 1.2e-32 113.2 0.0 2.4e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase AP_endonuc_2 PF01261.24 PRP75388.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Usp PF00582.26 PRP75388.1 - 0.0063 17.0 0.2 0.041 14.4 0.0 2.3 2 0 0 2 2 2 1 Universal stress protein family TAD2 PF18521.1 PRP75390.1 - 0.28 11.2 0.7 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Transactivation domain 2 DUF3818 PF12825.7 PRP75392.1 - 5.7e-15 55.2 0.3 9.3e-09 34.8 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) Img2 PF05046.14 PRP75393.1 - 1.1e-22 80.1 0.2 1.2e-22 80.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) LIM PF00412.22 PRP75394.1 - 9.9e-09 35.3 2.9 1.7e-08 34.6 2.9 1.3 1 0 0 1 1 1 1 LIM domain UQ_con PF00179.26 PRP75395.1 - 7.9e-27 93.6 0.0 1.5e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Leo1 PF04004.13 PRP75395.1 - 0.3 10.9 1.5 0.38 10.6 0.0 2.0 2 0 0 2 2 2 0 Leo1-like protein Pkinase_Tyr PF07714.17 PRP75396.1 - 1.1e-46 159.2 0.0 1.6e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75396.1 - 8.7e-41 140.0 0.0 1.6e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WW PF00397.26 PRP75396.1 - 4e-06 26.8 3.8 4e-06 26.8 3.8 2.6 2 0 0 2 2 2 1 WW domain APH PF01636.23 PRP75396.1 - 0.034 14.1 0.0 9.2 6.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP75396.1 - 0.043 13.1 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like KIX_2 PF16987.5 PRP75397.1 - 2e-09 37.3 0.8 1.1e-08 34.9 0.8 2.4 1 0 0 1 1 1 1 KIX domain Plasmid_stab_B PF10784.9 PRP75397.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Plasmid stability protein LCIB_C_CA PF18599.1 PRP75397.1 - 0.65 9.3 5.8 1.1 8.6 2.5 2.3 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases HNH_2 PF13391.6 PRP75398.1 - 0.0049 17.0 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease DiS_P_DiS PF06750.13 PRP75399.1 - 0.00047 20.2 0.8 1.3 9.2 0.1 2.5 2 0 0 2 2 2 2 Bacterial Peptidase A24 N-terminal domain Myosin-VI_CBD PF16521.5 PRP75399.1 - 0.079 13.0 0.0 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Myosin VI cargo binding domain Pkinase PF00069.25 PRP75400.1 - 2.1e-28 99.4 0.0 7.8e-15 54.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PRP75400.1 - 3.5e-08 33.1 0.0 0.0082 15.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PRP75400.1 - 2.9e-05 23.5 0.1 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP75400.1 - 0.00019 21.4 0.6 0.88 9.4 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family PIP49_C PF12260.8 PRP75400.1 - 0.0021 17.7 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 2 Protein-kinase domain of FAM69 ID PF18543.1 PRP75400.1 - 0.0056 16.7 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 2 Intracellular delivery domain Seadorna_VP7 PF07387.11 PRP75400.1 - 0.01 14.9 1.7 2.7 6.9 0.1 2.2 2 0 0 2 2 2 0 Seadornavirus VP7 DUF3993 PF13158.6 PRP75400.1 - 0.03 14.5 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) DUF3854 PF12965.7 PRP75400.1 - 0.052 13.5 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) Clathrin-link PF09268.10 PRP75400.1 - 0.11 11.9 0.0 21 4.6 0.0 2.6 2 0 0 2 2 2 0 Clathrin, heavy-chain linker DUF3188 PF11384.8 PRP75400.1 - 0.87 9.3 2.9 71 3.2 0.0 4.0 6 0 0 6 6 6 0 Protein of unknown function (DUF3188) Flu_B_NS1 PF02942.14 PRP75401.1 - 0.071 12.2 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) DUF3253 PF11625.8 PRP75402.1 - 0.076 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) TANGO2 PF05742.12 PRP75407.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Transport and Golgi organisation 2 RCC1 PF00415.18 PRP75408.1 - 4.8e-49 164.8 10.4 9.9e-13 48.5 0.0 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP75408.1 - 6.4e-24 83.2 28.0 5.1e-10 38.9 0.3 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 PRP75408.1 - 0.039 13.7 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split ESR1_C PF12743.7 PRP75410.1 - 0.079 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal WD40 PF00400.32 PRP75412.1 - 0.0015 19.3 0.1 0.011 16.6 0.1 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Peptidase_M50 PF02163.22 PRP75413.1 - 1.6e-15 57.1 0.0 2.2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M50 GCP_C_terminal PF04130.13 PRP75414.1 - 6.1e-46 157.3 3.2 1.3e-45 156.2 3.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PRP75414.1 - 2.3e-38 132.6 0.5 3.4e-38 132.0 0.5 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal SASA PF03629.18 PRP75416.1 - 7e-19 68.4 0.0 1.2e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase RicinB_lectin_2 PF14200.6 PRP75416.1 - 0.00094 19.9 2.8 0.014 16.1 0.4 3.1 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CarboxypepD_reg PF13620.6 PRP75416.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.3 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain F-box-like PF12937.7 PRP75417.1 - 5.3e-08 32.6 0.7 1.1e-07 31.6 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP75417.1 - 2.7e-07 30.3 0.5 2.7e-07 30.3 0.5 1.7 2 0 0 2 2 2 1 F-box domain DPBB_1 PF03330.18 PRP75418.1 - 0.03 14.6 0.4 0.081 13.2 0.1 1.9 2 1 0 2 2 2 0 Lytic transglycolase Arf PF00025.21 PRP75419.1 - 7.8e-62 207.8 0.0 9.7e-62 207.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PRP75419.1 - 3.7e-14 52.6 0.0 5.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP75419.1 - 8.3e-14 51.8 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PRP75419.1 - 1.9e-12 47.0 0.0 8.8e-10 38.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PRP75419.1 - 1.2e-11 44.3 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PRP75419.1 - 4.3e-09 36.1 0.0 5.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP75419.1 - 0.00055 20.0 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP75419.1 - 0.0023 17.5 0.1 0.0054 16.3 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 PRP75419.1 - 0.01 15.5 0.3 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 PRP75419.1 - 0.091 12.5 0.3 1.9 8.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MRP-S26 PF14943.6 PRP75423.1 - 0.091 12.7 10.9 0.15 12.0 10.9 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Topoisom_I_N PF02919.15 PRP75423.1 - 1.1 8.7 8.6 1.5 8.3 6.8 1.8 1 1 1 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF5442 PF17514.2 PRP75423.1 - 2.7 8.2 8.0 5 7.4 1.3 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5442) Cep57_MT_bd PF06657.13 PRP75423.1 - 5.9 7.4 12.8 3.7 8.1 0.9 3.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF3808 PF10300.9 PRP75424.1 - 3.9e-24 85.2 1.2 1.5e-23 83.3 0.4 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 PRP75424.1 - 1.6e-06 28.3 0.0 0.026 14.8 0.0 4.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP75424.1 - 0.00065 19.6 0.0 25 5.3 0.0 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP75424.1 - 0.00084 19.4 6.3 4 7.9 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP75424.1 - 0.087 12.9 0.0 17 5.8 0.0 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat G-alpha PF00503.20 PRP75425.1 - 3.6e-87 292.8 8.1 3.6e-87 292.8 8.1 2.4 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 PRP75425.1 - 1e-12 47.9 0.4 4.9e-09 35.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family SBF2 PF12335.8 PRP75425.1 - 1.5e-06 28.0 0.7 1.5e-06 28.0 0.7 2.7 3 0 0 3 3 3 1 Myotubularin protein Roc PF08477.13 PRP75425.1 - 7.8e-06 26.1 0.5 0.19 12.0 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PRP75425.1 - 0.00022 20.7 0.1 0.038 13.3 0.1 2.6 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 PRP75425.1 - 0.0053 16.5 0.5 0.026 14.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 PRP75425.1 - 0.039 14.0 1.2 8.5 6.5 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase BTB_2 PF02214.22 PRP75425.1 - 0.1 13.0 1.0 0.54 10.6 0.4 2.5 2 0 0 2 2 2 0 BTB/POZ domain ABC_tran PF00005.27 PRP75425.1 - 2.5 8.6 7.1 0.26 11.8 0.1 2.8 3 0 0 3 3 3 0 ABC transporter ICMT PF04140.14 PRP75426.1 - 2.6e-26 91.9 0.1 8.8e-26 90.2 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 PRP75426.1 - 5.5e-10 39.6 0.1 5.5e-10 39.6 0.1 2.0 3 0 0 3 3 3 1 Phospholipid methyltransferase MMACHC PF16690.5 PRP75426.1 - 0.0011 18.7 0.1 0.0017 18.1 0.1 1.2 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family DUF1295 PF06966.12 PRP75426.1 - 0.052 13.1 3.4 0.13 11.8 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) PDEase_I PF00233.19 PRP75427.1 - 1.4e-70 237.7 9.0 2.5e-70 236.9 9.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Clusterin PF01093.17 PRP75427.1 - 0.0095 15.0 2.1 0.028 13.5 0.2 2.3 2 0 0 2 2 2 1 Clusterin GWT1 PF06423.12 PRP75427.1 - 0.038 14.1 0.3 0.082 13.0 0.3 1.6 1 0 0 1 1 1 0 GWT1 Acetyltransf_1 PF00583.25 PRP75429.1 - 5.4e-16 58.9 0.0 6.7e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP75429.1 - 8.5e-13 48.5 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP75429.1 - 4.3e-11 42.9 0.1 7e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP75429.1 - 1.5e-09 38.1 0.0 2.2e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP75429.1 - 8e-08 32.2 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PRP75429.1 - 0.00076 19.6 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PRP75429.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 PRP75429.1 - 0.0033 16.9 0.4 0.0038 16.7 0.4 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Nudix_hydro PF18290.1 PRP75429.1 - 0.018 15.0 0.0 0.062 13.3 0.0 1.8 2 0 0 2 2 2 0 Nudix hydrolase domain Acetyltransf_3 PF13302.7 PRP75429.1 - 0.024 15.3 0.0 0.032 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 PRP75429.1 - 0.056 13.3 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LRR_8 PF13855.6 PRP75430.1 - 1.1e-13 50.7 13.5 3.7e-11 42.6 6.6 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PRP75430.1 - 1.3e-08 35.0 8.1 1.7e-05 25.1 3.4 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP75430.1 - 1.4e-06 28.0 8.6 0.028 14.9 0.2 4.6 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP75430.1 - 0.00025 20.8 10.4 0.14 12.3 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeat TRPM_tetra PF16519.5 PRP75432.1 - 0.14 12.3 0.0 4.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF3712 PF12505.8 PRP75433.1 - 1.4e-05 25.4 1.5 0.0056 16.9 1.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3712) PreAtp-grasp PF18604.1 PRP75434.1 - 0.17 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Pre ATP-grasp domain VID27 PF08553.10 PRP75435.1 - 8.5e-45 153.3 1.2 1e-44 153.1 0.1 1.6 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain Phage_Gp23 PF10669.9 PRP75440.1 - 0.012 16.0 0.3 0.013 15.8 0.3 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) FSAP_sig_propep PF03032.15 PRP75440.1 - 0.16 12.0 4.8 0.3 11.1 4.8 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide Aquarius_N PF16399.5 PRP75445.1 - 0.0057 14.8 0.2 0.0073 14.4 0.2 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus Myosin_head PF00063.21 PRP75446.1 - 1.1e-245 817.1 2.1 1.2e-245 816.9 2.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Zeta_toxin PF06414.12 PRP75446.1 - 0.071 12.4 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 PRP75446.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PRP75446.1 - 0.19 12.1 0.0 0.49 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain KBP_C PF12309.8 PRP75449.1 - 0.00054 19.6 0.0 0.00058 19.5 0.0 1.1 1 0 0 1 1 1 1 KIF-1 binding protein C terminal PAS_8 PF13188.7 PRP75450.1 - 0.0063 16.5 0.0 0.009 16.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain Aminotran_1_2 PF00155.21 PRP75452.1 - 3.8e-33 115.2 0.0 4.7e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5395 PF17373.2 PRP75452.1 - 0.068 13.8 0.0 0.14 12.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5395) Cys_Met_Meta_PP PF01053.20 PRP75452.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 PRP75452.1 - 0.19 11.0 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DIOX_N PF14226.6 PRP75453.1 - 7.7e-06 26.6 0.1 1.7e-05 25.5 0.1 1.6 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PRP75453.1 - 0.0016 18.9 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 PRP75454.1 - 1.7e-28 99.5 31.9 5.7e-21 74.8 12.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP75454.1 - 1.2e-22 80.4 12.9 5.3e-22 78.3 12.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1996 PF09362.10 PRP75456.1 - 5.9e-71 239.2 3.0 7.6e-71 238.8 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HigB_toxin PF09907.9 PRP75458.1 - 4 7.7 6.7 60 4.0 0.1 3.7 2 1 2 4 4 4 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system Ank_3 PF13606.6 PRP75459.1 - 2.4e-05 24.3 0.6 7.6 7.5 0.0 5.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 PRP75459.1 - 0.00045 20.7 0.0 0.0023 18.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box-like PF12937.7 PRP75459.1 - 0.68 9.9 3.8 3.9 7.4 1.1 3.3 3 1 0 3 3 3 0 F-box-like TTKRSYEDQ PF10212.9 PRP75461.1 - 2e-22 79.9 20.3 2.2e-17 63.3 14.5 5.9 2 2 4 6 6 6 2 Predicted coiled-coil domain-containing protein KLRAQ PF10205.9 PRP75461.1 - 4.8e-06 26.7 8.5 4.8e-06 26.7 8.5 8.1 5 3 5 10 10 10 1 Predicted coiled-coil domain-containing protein Mito_carr PF00153.27 PRP75462.1 - 1.3e-64 214.1 4.7 3e-22 78.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 PRP75463.1 - 7.4e-51 169.0 29.0 1.9e-07 31.7 0.1 11.7 13 0 0 13 13 13 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75463.1 - 2e-11 44.1 8.3 0.014 15.6 0.0 6.6 4 2 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP75463.1 - 1.1e-05 24.3 7.3 0.27 9.8 0.1 4.9 3 2 2 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 PRP75463.1 - 0.00012 21.6 8.8 0.015 14.7 0.1 4.1 2 1 1 4 4 4 2 WD40-like domain EPTP PF03736.17 PRP75463.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 EPTP domain PALB2_WD40 PF16756.5 PRP75463.1 - 0.4 9.6 9.0 0.62 8.9 0.0 4.8 4 2 3 7 7 7 0 Partner and localizer of BRCA2 WD40 domain WH2 PF02205.20 PRP75465.1 - 3.6e-05 23.4 1.5 0.087 12.7 0.1 2.4 2 0 0 2 2 2 2 WH2 motif LicD PF04991.13 PRP75466.1 - 1.3e-20 74.6 1.5 1.2e-15 58.3 0.8 2.4 1 1 1 2 2 2 2 LicD family MOSC PF03473.17 PRP75467.1 - 3.2e-22 78.9 0.0 4.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 PRP75467.1 - 6.6e-09 35.7 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Formyl_trans_N PF00551.19 PRP75468.1 - 3.7e-51 173.4 0.2 4.4e-51 173.2 0.2 1.1 1 0 0 1 1 1 1 Formyl transferase CBS PF00571.28 PRP75468.1 - 0.12 12.9 0.2 0.45 11.0 0.1 1.9 2 0 0 2 2 2 0 CBS domain Ribosomal_L1 PF00687.21 PRP75469.1 - 9.5e-47 159.4 1.9 9.5e-47 159.4 1.9 2.1 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family RRM_1 PF00076.22 PRP75470.1 - 2e-25 88.4 0.0 6.3e-14 51.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PRP75470.1 - 2.3e-06 27.3 0.0 0.0028 17.5 0.0 2.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 PRP75470.1 - 0.00021 20.9 0.0 0.083 12.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PRP75470.1 - 0.0051 16.8 0.0 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif CTP_transf_like PF01467.26 PRP75471.1 - 1.5e-09 38.2 0.1 1.7e-09 38.0 0.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 PRP75471.1 - 0.016 15.1 0.4 0.034 14.0 0.4 1.5 1 1 0 1 1 1 0 FAD synthetase SAP PF02037.27 PRP75474.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain Pex2_Pex12 PF04757.14 PRP75478.1 - 1.1e-26 93.9 12.5 2.2e-26 92.9 11.5 1.8 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 PRP75478.1 - 0.029 14.3 1.6 0.063 13.2 1.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP75478.1 - 0.15 11.9 1.5 0.35 10.7 1.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP75478.1 - 0.2 12.1 1.0 0.45 10.9 1.0 1.6 1 0 0 1 1 1 0 Ring finger domain Pkinase PF00069.25 PRP75479.1 - 5.9e-68 229.1 0.1 5.9e-68 229.1 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75479.1 - 4.7e-45 153.9 0.1 4.7e-45 153.9 0.1 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase RNA_pol_Rpb1_1 PF04997.12 PRP75480.1 - 1.8e-104 349.5 0.6 3.1e-104 348.6 0.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 PRP75480.1 - 1.8e-103 345.6 0.1 3.3e-103 344.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PRP75480.1 - 5.4e-72 241.4 0.1 1.3e-71 240.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 PRP75480.1 - 8.7e-64 214.9 0.1 2e-63 213.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 PRP75480.1 - 1.3e-48 164.9 0.1 3.5e-48 163.5 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 PRP75480.1 - 4.2e-41 140.1 4.5 1.1e-40 138.8 4.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 PRP75480.1 - 1.5e-38 131.1 1.5 2e-38 130.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 PRP75480.1 - 2.6e-16 59.0 380.4 0.55 10.7 16.7 17.8 2 1 28 31 31 31 29 RNA polymerase Rpb1 C-terminal repeat ADK PF00406.22 PRP75482.1 - 1.7e-15 57.5 0.9 2.9e-15 56.7 0.1 1.9 2 0 0 2 2 2 1 Adenylate kinase Dpy-30 PF05186.13 PRP75482.1 - 2.6e-15 55.8 0.1 6.1e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.6 PRP75482.1 - 1.1e-09 38.9 0.1 1.1e-09 38.9 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 PRP75482.1 - 3.8e-05 24.2 0.6 0.00012 22.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Epimerase PF01370.21 PRP75482.1 - 0.0015 18.0 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3479 PF11965.8 PRP75482.1 - 0.0041 17.3 0.1 0.0041 17.3 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3479) Hydin_ADK PF17213.3 PRP75482.1 - 0.0044 17.3 0.5 0.016 15.5 0.5 2.2 1 1 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 PRP75482.1 - 0.026 14.8 5.1 1 9.6 0.6 3.5 3 1 1 4 4 4 0 AAA domain RuvB_N PF05496.12 PRP75482.1 - 0.077 12.7 0.3 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Y2_Tnp PF04986.13 PRP75482.1 - 2.2 8.3 4.4 1.2 9.1 1.0 2.3 3 0 0 3 3 3 0 Putative transposase Pkinase_Tyr PF07714.17 PRP75484.1 - 6.2e-60 202.7 0.1 1.8e-59 201.1 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75484.1 - 2.4e-42 145.2 0.1 3.6e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP75484.1 - 5.1e-12 45.8 38.1 5.3e-05 23.5 2.3 6.1 3 1 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP75484.1 - 3.2e-09 36.4 43.5 1.7e-05 24.5 9.5 5.5 3 2 2 5 5 5 4 Leucine rich repeat Adeno_E3_CR2 PF02439.15 PRP75484.1 - 0.0078 15.9 0.6 0.015 15.1 0.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Pkinase_fungal PF17667.1 PRP75484.1 - 0.012 14.4 0.2 0.021 13.6 0.2 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PRP75484.1 - 0.013 14.9 0.8 0.022 14.1 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 PRP75484.1 - 0.038 14.0 22.0 0.29 11.3 0.2 6.9 7 0 0 7 7 7 0 Leucine Rich repeat LRR_9 PF14580.6 PRP75484.1 - 0.2 11.2 1.9 0.48 9.9 1.7 1.8 1 1 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 PRP75484.1 - 9.1 7.3 26.7 4 8.3 0.2 7.5 7 1 1 8 8 8 0 Leucine Rich Repeat Phospholip_B PF04916.13 PRP75486.1 - 3.1e-156 521.0 6.7 3.8e-156 520.8 6.7 1.0 1 0 0 1 1 1 1 Phospholipase B DUF2711 PF10924.8 PRP75486.1 - 0.049 13.2 0.3 0.11 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) Ank_2 PF12796.7 PRP75487.1 - 7.5e-41 138.6 0.1 7.7e-10 39.2 0.0 6.9 3 2 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75487.1 - 1.1e-32 111.9 10.1 6.7e-07 29.7 0.0 9.7 5 3 5 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP75487.1 - 1.6e-19 69.7 7.3 0.014 15.7 0.0 11.1 6 3 6 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75487.1 - 2.1e-16 58.3 0.5 2.4 9.0 0.0 11.5 13 0 0 13 13 13 2 Ankyrin repeat Ank PF00023.30 PRP75487.1 - 4.1e-16 58.6 12.7 2.8 8.5 0.0 13.0 11 3 2 13 13 13 1 Ankyrin repeat F-box PF00646.33 PRP75487.1 - 0.099 12.6 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 F-box domain Lipase_GDSL_2 PF13472.6 PRP75487.1 - 0.95 9.8 3.8 23 5.3 0.2 3.9 1 1 3 4 4 4 0 GDSL-like Lipase/Acylhydrolase family Cullin PF00888.22 PRP75490.1 - 2.3e-12 46.4 0.1 2.6e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Cullin family HbrB PF08539.11 PRP75490.1 - 0.0018 18.3 0.3 0.0023 17.9 0.3 1.2 1 0 0 1 1 1 1 HbrB-like Guanylate_cyc PF00211.20 PRP75490.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.6 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain Peptidase_M18 PF02127.15 PRP75491.1 - 5.5e-161 536.2 0.0 6.8e-161 535.9 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 PRP75491.1 - 1.8e-06 27.2 0.1 3.1e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase GREB1 PF15782.5 PRP75493.1 - 6.8e-56 189.4 20.1 3.9e-13 47.6 2.1 6.6 5 2 2 7 7 7 6 Gene regulated by oestrogen in breast cancer Glyco_hydro_130 PF04041.13 PRP75493.1 - 0.00019 20.5 0.6 0.36 9.7 0.1 2.3 2 0 0 2 2 2 2 beta-1,4-mannooligosaccharide phosphorylase Rhodanese PF00581.20 PRP75493.1 - 0.0024 18.4 0.1 9.2 6.8 0.0 4.5 5 0 0 5 5 5 1 Rhodanese-like domain PET PF06297.14 PRP75493.1 - 0.0031 17.8 0.0 6.5 7.1 0.0 2.9 2 0 0 2 2 2 2 PET Domain HD_5 PF13487.6 PRP75493.1 - 0.0052 17.0 0.1 7.4 6.9 0.0 2.9 2 0 0 2 2 2 2 HD domain DUF5496 PF17600.2 PRP75493.1 - 0.015 15.3 0.2 47 4.1 0.0 4.1 3 0 0 3 3 3 0 Family of unknown function (DUF5496) UN_NPL4 PF11543.8 PRP75493.1 - 0.11 13.0 5.2 17 6.0 0.3 4.4 3 2 0 3 3 3 0 Nuclear pore localisation protein NPL4 RE_BsaWI PF18643.1 PRP75493.1 - 0.17 11.8 1.4 1.7 8.6 0.0 3.2 4 0 0 4 4 4 0 BsaWI restriction endonuclease type 2 SBP_bac_3 PF00497.20 PRP75493.1 - 0.17 11.3 1.2 15 5.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 DUF4162 PF13732.6 PRP75493.1 - 0.22 12.3 9.8 5.3 7.8 1.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4162) Mu-like_Pro PF10123.9 PRP75493.1 - 0.4 10.2 10.3 1.3 8.5 2.1 2.7 2 0 0 2 2 2 0 Mu-like prophage I protein Acyl-CoA_dh_1 PF00441.24 PRP75494.1 - 2.8e-47 160.7 0.1 3.8e-47 160.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PRP75494.1 - 3.1e-25 89.0 0.0 5.5e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PRP75494.1 - 1.7e-24 85.8 0.0 3.1e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PRP75494.1 - 5.4e-24 85.0 0.0 1e-23 84.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain BRE PF06113.12 PRP75494.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) adh_short PF00106.25 PRP75495.1 - 4.4e-29 101.3 0.2 7.9e-29 100.5 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP75495.1 - 2.3e-22 79.7 0.2 4e-22 78.9 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP75495.1 - 1.3e-06 28.4 0.1 2.6e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP75495.1 - 0.088 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Transferrin PF00405.17 PRP75496.1 - 0.056 12.6 0.0 0.14 11.3 0.0 1.6 2 0 0 2 2 2 0 Transferrin MCD PF05292.11 PRP75497.1 - 0.21 11.1 0.7 0.72 9.4 0.1 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain PhoLip_ATPase_C PF16212.5 PRP75498.1 - 2.1e-71 240.6 19.9 2.1e-71 240.6 19.9 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP75498.1 - 2.8e-23 81.4 1.8 2.8e-23 81.4 1.8 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PRP75498.1 - 3.7e-10 40.5 2.7 0.00034 21.0 0.5 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PRP75498.1 - 2.2e-09 37.1 0.0 2.2e-09 37.1 0.0 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 PRP75498.1 - 1.1e-06 28.6 0.0 5.4e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP75498.1 - 4e-05 23.5 0.0 9.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1604 PF07713.13 PRP75499.1 - 0.3 11.0 3.8 0.24 11.3 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1604) Prefoldin PF02996.17 PRP75500.1 - 3e-15 56.2 0.1 6.4e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 PRP75500.1 - 1e-07 31.9 0.3 1e-07 31.9 0.3 1.9 2 0 0 2 2 2 1 Prefoldin subunit SARA PF11409.8 PRP75500.1 - 5.3e-05 23.3 0.1 67 3.8 0.0 5.6 6 0 0 6 6 6 0 Smad anchor for receptor activation (SARA) Cwf_Cwc_15 PF04889.12 PRP75500.1 - 2.5 7.8 30.6 5.5 6.7 30.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein POP1 PF06978.11 PRP75501.1 - 1e-38 133.4 18.6 8.7e-22 78.1 7.2 2.2 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 PRP75501.1 - 1.2e-21 76.8 0.0 3.5e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 PRP75501.1 - 7.3e-07 28.8 0.0 0.003 17.0 0.0 3.6 4 0 0 4 4 4 2 Aminomethyltransferase folate-binding domain CsrA PF02599.16 PRP75501.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Global regulator protein family CENP-B_dimeris PF09026.10 PRP75502.1 - 0.0025 18.1 2.2 0.0055 17.1 2.2 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_r1_1 PF03979.14 PRP75502.1 - 0.032 14.3 7.5 0.26 11.4 8.7 1.8 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 F-box-like PF12937.7 PRP75502.1 - 0.062 13.2 0.3 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 PRP75502.1 - 0.078 12.9 0.5 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 F-box domain Nucleo_P87 PF07267.11 PRP75502.1 - 0.083 11.7 0.4 0.11 11.3 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DNA_pol_phi PF04931.13 PRP75502.1 - 0.13 10.3 3.4 0.17 9.9 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4611 PF15387.6 PRP75502.1 - 0.77 10.0 7.4 6.1 7.1 6.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PDEase_I PF00233.19 PRP75503.1 - 3.6e-82 275.7 4.5 6.5e-82 274.8 4.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 PRP75503.1 - 0.0029 17.8 0.0 0.0079 16.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HD PF01966.22 PRP75503.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.8 1 0 0 1 1 1 0 HD domain DUF16 PF01519.16 PRP75503.1 - 0.15 12.5 2.7 0.62 10.6 2.7 2.0 1 0 0 1 1 1 0 Protein of unknown function DUF16 LAM_C PF12544.8 PRP75503.1 - 0.18 12.0 2.6 0.58 10.3 0.3 2.8 3 0 0 3 3 3 0 Lysine-2,3-aminomutase COX15-CtaA PF02628.15 PRP75504.1 - 8.8e-99 330.6 9.1 1.4e-98 330.0 9.1 1.3 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Ribosom_S12_S23 PF00164.25 PRP75504.1 - 2.1e-48 162.7 0.3 3.6e-48 161.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S12/S23 OppC_N PF12911.7 PRP75504.1 - 0.79 9.7 0.0 0.79 9.7 0.0 3.4 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Ribosomal_S4e PF00900.20 PRP75505.1 - 3.2e-32 110.3 0.1 5.5e-32 109.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 PRP75505.1 - 4e-22 77.6 0.0 2.6e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 PRP75505.1 - 9.1e-22 76.9 5.0 2.1e-21 75.7 5.0 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 PRP75505.1 - 1.4e-09 37.5 0.1 2.5e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 PRP75505.1 - 3.7e-06 26.7 0.4 3.7e-06 26.7 0.4 2.6 3 0 0 3 3 3 1 KOW motif Sipho_tail PF05709.11 PRP75505.1 - 0.022 14.2 0.0 0.14 11.5 0.0 1.9 1 1 0 1 1 1 0 Phage tail protein S4_2 PF13275.6 PRP75505.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 S4 domain NMT1 PF09084.11 PRP75506.1 - 3.3e-36 125.2 0.0 4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 PRP75506.1 - 3.5e-07 30.2 0.0 2.4e-06 27.5 0.0 1.9 1 1 1 2 2 2 1 NMT1-like family DUF4143 PF13635.6 PRP75506.1 - 0.054 13.6 0.0 0.092 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) Pom PF17251.2 PRP75508.1 - 0.017 14.4 3.2 0.16 11.3 0.0 2.3 1 1 0 2 2 2 0 Protochlamydia outer membrane protein MukF_M PF17192.4 PRP75508.1 - 0.09 12.5 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 MukF middle domain CBM_20 PF00686.19 PRP75509.1 - 5.4e-13 48.7 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain RabGAP-TBC PF00566.18 PRP75509.1 - 0.00019 21.2 0.3 0.04 13.6 0.1 3.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 PRP75510.1 - 1.4e-58 198.3 0.0 3e-58 197.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75510.1 - 3.8e-41 141.1 0.0 5.8e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP75510.1 - 1.5e-05 24.5 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP75510.1 - 0.014 15.3 0.1 0.65 9.9 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP75510.1 - 0.077 11.8 0.0 0.077 11.8 0.0 2.0 2 1 1 3 3 3 0 Fungal protein kinase Lipase_3 PF01764.25 PRP75512.1 - 2.8e-36 124.5 0.0 3.8e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 PRP75512.1 - 0.00012 21.7 0.0 0.0021 17.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 PRP75512.1 - 0.0047 16.7 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 PRP75512.1 - 0.0074 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP75512.1 - 0.025 15.2 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_24 PF13479.6 PRP75512.1 - 0.037 13.8 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain ANAPC4_WD40 PF12894.7 PRP75513.1 - 0.00026 21.3 1.1 0.94 9.8 0.0 4.4 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP75513.1 - 0.00052 20.8 19.9 0.028 15.3 0.9 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Reg_prop PF07494.11 PRP75513.1 - 0.0091 16.1 1.4 23 5.7 0.0 4.4 3 0 0 3 3 3 2 Two component regulator propeller zf-UBP PF02148.19 PRP75513.1 - 0.59 10.5 6.2 0.11 12.8 1.0 2.5 3 0 0 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein Pkinase_Tyr PF07714.17 PRP75515.1 - 7.2e-52 176.2 0.0 3.8e-50 170.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75515.1 - 6.9e-33 114.1 0.0 1.2e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP75515.1 - 3.2e-09 37.2 6.1 3.2e-09 37.2 6.1 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Kelch_5 PF13854.6 PRP75515.1 - 0.0042 17.0 0.8 0.87 9.6 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 PRP75515.1 - 0.022 14.7 0.2 7.6 6.7 0.0 3.3 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.6 PRP75515.1 - 0.031 14.3 1.9 6.5 6.8 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF3180 PF11377.8 PRP75515.1 - 0.77 9.9 4.8 3 8.0 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Ank_2 PF12796.7 PRP75517.1 - 1e-79 263.2 0.5 2.4e-11 44.1 0.1 8.0 3 2 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75517.1 - 4.9e-59 196.0 19.4 1.8e-06 28.4 0.1 13.0 3 3 13 16 16 16 14 Ankyrin repeats (many copies) Ank PF00023.30 PRP75517.1 - 3.6e-37 125.2 20.9 0.43 11.1 0.0 18.2 18 2 2 20 20 19 10 Ankyrin repeat Ank_3 PF13606.6 PRP75517.1 - 9.1e-34 111.7 0.9 4.7 8.1 0.0 17.2 17 1 1 18 18 18 1 Ankyrin repeat Ank_5 PF13857.6 PRP75517.1 - 4.5e-33 112.9 13.5 0.96 9.8 0.0 16.8 3 2 15 18 18 18 11 Ankyrin repeats (many copies) BiPBP_C PF06832.12 PRP75517.1 - 3.5e-09 36.6 1.6 0.28 11.2 0.0 5.5 4 1 0 5 5 5 3 Penicillin-Binding Protein C-terminus Family DUF4671 PF15710.5 PRP75517.1 - 0.00021 20.3 17.3 0.065 12.1 0.3 6.6 3 1 4 8 8 8 2 Domain of unknown function (DUF4671) DUF3734 PF12536.8 PRP75517.1 - 0.0005 20.4 19.8 9.7 6.6 0.1 8.6 4 2 9 13 13 13 1 Patatin phospholipase Glyco_hydro_79C PF16862.5 PRP75517.1 - 0.004 18.0 0.3 69 4.4 0.0 6.0 3 2 1 4 4 4 0 Glycosyl hydrolase family 79 C-terminal beta domain Paramyx_P_V_C PF03210.13 PRP75517.1 - 0.0051 16.6 5.1 12 5.6 0.0 5.7 3 2 2 7 7 7 1 Paramyxovirus P/V phosphoprotein C-terminal Malate_DH PF12434.8 PRP75517.1 - 0.043 13.8 20.2 36 4.5 0.0 9.6 11 0 0 11 11 11 0 Malate dehydrogenase enzyme CENP-R PF06729.12 PRP75517.1 - 4.5 7.2 7.4 1.1e+02 2.7 0.1 4.8 5 0 0 5 5 5 0 Kinetochore component, CENP-R Methyltransf_24 PF13578.6 PRP75517.1 - 7.5 7.6 18.8 56 4.8 0.3 6.1 2 1 1 4 4 4 0 Methyltransferase domain Cu-oxidase_2 PF07731.14 PRP75518.1 - 2.1e-37 127.9 0.8 2.1e-37 127.9 0.8 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 PRP75518.1 - 2.1e-30 105.2 10.0 2.3e-28 98.6 0.9 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 PRP75518.1 - 3.4e-29 102.0 4.7 7e-27 94.5 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 PRP75518.1 - 0.011 15.8 0.0 1.5 9.0 0.0 3.5 2 2 0 2 2 2 0 Cupredoxin-like domain FTR1 PF03239.14 PRP75519.1 - 7.8e-62 209.2 10.8 9.7e-61 205.6 10.8 1.9 1 1 0 1 1 1 1 Iron permease FTR1 family DUF5305 PF17231.2 PRP75519.1 - 0.12 11.7 0.1 3.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5305) DUF5337 PF17272.2 PRP75519.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5337) EF-hand_1 PF00036.32 PRP75520.1 - 1.4e-20 71.2 10.6 3.5e-06 26.2 0.0 4.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PRP75520.1 - 7e-19 66.1 9.9 3.9e-05 23.2 0.0 4.8 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 PRP75520.1 - 8.6e-18 64.6 6.2 1.1e-11 45.1 1.8 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP75520.1 - 1.2e-16 59.4 9.1 1.8e-06 27.2 0.3 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PRP75520.1 - 5e-14 51.9 6.7 0.0016 18.3 0.5 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 PRP75520.1 - 0.0023 17.9 1.1 0.38 10.7 0.1 3.0 1 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PRP75520.1 - 0.0037 17.6 1.3 2.3 8.5 0.1 3.5 2 2 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 PRP75520.1 - 0.019 15.3 0.0 0.058 13.7 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain HAUS4 PF14735.6 PRP75521.1 - 0.021 14.5 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 MCC-bdg_PDZ PF10506.9 PRP75521.1 - 0.15 12.1 1.6 0.39 10.8 0.2 2.1 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome M PF02370.16 PRP75521.1 - 0.19 12.4 0.2 25 5.9 0.1 2.5 2 0 0 2 2 2 0 M protein repeat TMF_DNA_bd PF12329.8 PRP75521.1 - 0.25 11.3 4.1 0.44 10.6 4.1 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADK PF00406.22 PRP75522.1 - 4.4e-47 160.0 0.0 5.8e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PRP75522.1 - 2e-23 83.3 0.0 3.2e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 PRP75522.1 - 1.4e-15 56.9 0.1 2.8e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 PRP75522.1 - 3.1e-05 24.5 0.0 6.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PRP75522.1 - 6.8e-05 23.1 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP75522.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF547 PF04784.14 PRP75524.1 - 1.4e-07 31.6 0.0 3.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Exonuc_V_gamma PF04257.14 PRP75524.1 - 0.056 11.7 0.1 0.085 11.1 0.1 1.2 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit DUF4987 PF16377.5 PRP75524.1 - 0.19 11.9 0.0 0.44 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Mito_carr PF00153.27 PRP75526.1 - 7e-68 224.6 0.8 4.3e-23 81.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 PRP75526.1 - 3.4e-20 70.2 5.8 2.4e-06 27.0 0.2 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PRP75526.1 - 4.1e-20 69.8 5.8 1.7e-06 27.1 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PRP75526.1 - 5.1e-20 71.7 7.8 2.2e-11 44.0 3.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP75526.1 - 2.4e-12 45.7 9.4 4.6e-05 22.7 0.2 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PRP75526.1 - 5.8e-09 35.7 6.2 0.0022 17.8 0.6 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP75526.1 - 2.6e-08 34.2 0.6 0.0003 21.1 0.2 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF569 PF04601.13 PRP75526.1 - 8.5e-05 22.3 0.2 0.0088 15.7 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF569) Fascin PF06268.13 PRP75526.1 - 0.00012 22.3 0.5 0.11 12.7 0.1 2.4 1 1 1 2 2 2 2 Fascin domain RicinB_lectin_2 PF14200.6 PRP75526.1 - 0.00022 21.9 0.1 0.0011 19.6 0.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like EF-hand_10 PF14788.6 PRP75526.1 - 0.049 13.5 10.5 4.7 7.2 0.1 4.0 2 2 2 4 4 4 0 EF hand Adenine_glyco PF03352.13 PRP75526.1 - 0.063 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyladenine glycosylase EF-hand_9 PF14658.6 PRP75526.1 - 0.065 13.6 0.1 3.3 8.1 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 PRP75526.1 - 0.077 13.0 2.4 4.1 7.4 0.1 2.8 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand FUSC_2 PF13515.6 PRP75527.1 - 1.3e-17 64.1 12.0 1.3e-17 64.1 12.0 3.0 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 PRP75527.1 - 2.2e-12 47.3 2.9 1.4e-07 31.6 0.2 2.3 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC PF04632.12 PRP75527.1 - 2.6e-11 42.8 18.8 4e-09 35.6 4.3 2.7 2 1 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2_N PF10337.9 PRP75527.1 - 2.4e-08 33.5 0.2 2.4e-08 33.5 0.2 2.8 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 PRP75527.1 - 1.4e-07 30.7 9.2 4.8e-07 29.0 3.0 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter Syntaxin-6_N PF09177.11 PRP75527.1 - 0.27 11.8 3.6 6.9 7.3 1.1 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Med2 PF11214.8 PRP75527.1 - 0.29 11.3 1.9 5.8 7.1 0.1 2.6 2 0 0 2 2 2 0 Mediator complex subunit 2 bZIP_1 PF00170.21 PRP75528.1 - 8.7e-11 41.8 12.2 1.7e-10 40.8 12.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PRP75528.1 - 3.9e-09 36.9 8.3 8.2e-09 35.9 8.3 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 PRP75528.1 - 3.9e-06 26.8 12.1 3.9e-06 26.8 12.1 2.4 2 1 1 3 3 3 2 Basic region leucine zipper DivIC PF04977.15 PRP75528.1 - 0.0018 18.0 0.4 0.0018 18.0 0.4 2.0 2 0 0 2 2 2 1 Septum formation initiator DUF779 PF05610.11 PRP75528.1 - 0.022 15.0 0.0 0.058 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF779) UPF0242 PF06785.11 PRP75528.1 - 0.25 11.4 8.7 0.53 10.4 8.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 PRP75528.1 - 0.46 10.7 7.9 1 9.6 0.7 2.9 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF1168 PF06658.12 PRP75529.1 - 4.5e-20 71.9 48.2 8.9e-19 67.7 48.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) JAB PF01398.21 PRP75530.1 - 6.4e-35 119.7 0.1 1e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 PRP75530.1 - 2.5e-23 82.8 0.4 4.4e-23 82.0 0.4 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 PRP75530.1 - 0.0005 19.8 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 PRP75530.1 - 0.0024 18.0 0.1 0.0052 16.9 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) 2OG-FeII_Oxy_3 PF13640.6 PRP75531.1 - 2.1e-11 44.6 0.0 3.2e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 PRP75531.1 - 0.021 14.9 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP75531.1 - 0.13 13.1 0.0 0.3 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2462 PF09495.10 PRP75533.1 - 0.00076 20.2 8.4 0.00076 20.2 8.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) RR_TM4-6 PF06459.12 PRP75533.1 - 0.34 10.7 4.8 0.4 10.5 4.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 XG_FTase PF03254.13 PRP75534.1 - 2.7e-11 42.8 0.1 3.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase DUF4304 PF14137.6 PRP75535.1 - 0.16 12.1 0.0 0.16 12.1 0.0 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4304) Guanylate_cyc PF00211.20 PRP75536.1 - 2.3e-34 118.6 0.1 4.2e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain dCache_1 PF02743.18 PRP75536.1 - 4.8e-05 23.3 1.2 0.0001 22.2 1.2 1.6 1 0 0 1 1 1 1 Cache domain Sugar-bind PF04198.13 PRP75536.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain Methyltr_RsmB-F PF01189.17 PRP75537.1 - 5.4e-71 238.4 0.0 8.2e-71 237.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 PRP75537.1 - 1.4e-11 44.7 0.0 5.9e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 PRP75537.1 - 0.00024 21.3 0.0 0.00048 20.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 PRP75537.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PRP75537.1 - 0.01 16.5 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 PRP75537.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 PRP75537.1 - 0.033 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 PRP75537.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DUF3592 PF12158.8 PRP75538.1 - 9.1e-10 38.8 0.5 1.3e-09 38.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) GET2 PF08690.10 PRP75538.1 - 0.0058 16.3 0.1 0.0076 16.0 0.1 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 Asp_protease PF09668.10 PRP75539.1 - 1.1e-57 193.2 0.5 1.9e-57 192.4 0.5 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PRP75539.1 - 9.1e-23 80.7 0.0 2.7e-22 79.1 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.31 PRP75539.1 - 2.6e-11 43.2 0.4 7e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain ubiquitin PF00240.23 PRP75539.1 - 4.4e-11 42.4 0.1 9.8e-11 41.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Asp_protease_2 PF13650.6 PRP75539.1 - 5.7e-11 42.9 0.0 2.7e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 PRP75539.1 - 2.3e-06 27.4 0.0 5.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 PRP75539.1 - 0.0012 18.7 0.5 0.0024 17.7 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.20 PRP75539.1 - 0.0037 17.5 0.0 0.013 15.8 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease UBA_3 PF09288.10 PRP75539.1 - 0.01 15.7 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain RuvA_C PF07499.13 PRP75539.1 - 0.12 12.8 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 RuvA, C-terminal domain MAS20 PF02064.15 PRP75539.1 - 4.3 7.4 7.8 1.7 8.7 0.6 2.6 2 1 1 3 3 3 0 MAS20 protein import receptor Pkinase PF00069.25 PRP75540.1 - 7.7e-54 182.8 0.0 9.4e-37 126.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75540.1 - 4.9e-25 88.3 0.0 8.7e-18 64.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP75540.1 - 0.0011 18.4 0.0 0.41 9.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 PRP75540.1 - 0.0034 17.4 0.0 0.3 11.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family DEAD PF00270.29 PRP75542.1 - 8.1e-40 136.4 0.0 1.4e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP75542.1 - 7.7e-28 97.1 0.1 1.8e-25 89.4 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 PRP75542.1 - 6.7e-09 36.0 0.0 2e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PRP75542.1 - 0.0013 18.1 0.1 0.0031 16.9 0.0 1.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit S10_plectin PF03501.15 PRP75543.1 - 5.3e-33 113.0 0.1 6.9e-33 112.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain SYS1 PF09801.9 PRP75544.1 - 3.5e-15 56.4 8.0 3.7e-15 56.3 8.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network SRF-TF PF00319.18 PRP75546.1 - 5.1e-21 73.9 0.2 8.2e-21 73.2 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cytochrom_B558a PF05038.13 PRP75546.1 - 0.029 13.9 0.1 0.029 13.9 0.1 1.7 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF1447 PF07288.11 PRP75546.1 - 0.24 11.5 0.9 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) DDE_5 PF13546.6 PRP75546.1 - 3.4 6.9 7.9 0.92 8.8 4.7 1.6 2 0 0 2 2 2 0 DDE superfamily endonuclease PBP1_TM PF14812.6 PRP75546.1 - 4.2 7.8 9.5 6.2 7.3 7.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.32 PRP75547.1 - 3e-15 56.3 9.7 0.00085 20.1 0.1 9.6 11 0 0 11 11 11 2 WD domain, G-beta repeat Prefoldin PF02996.17 PRP75547.1 - 0.0037 17.2 1.6 0.0037 17.2 1.6 7.9 6 2 2 8 8 8 2 Prefoldin subunit Nucleoporin_N PF08801.11 PRP75547.1 - 0.0048 15.7 0.4 0.17 10.6 0.0 3.2 4 0 0 4 4 4 1 Nup133 N terminal like Rho_Binding PF08912.11 PRP75547.1 - 0.018 15.8 3.3 0.018 15.8 3.3 8.0 5 3 4 9 9 9 0 Rho Binding DASH_Dam1 PF08653.10 PRP75547.1 - 0.57 10.0 3.9 16 5.4 1.0 3.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 Halo_GVPC PF05465.13 PRP75547.1 - 0.88 9.9 6.1 0.93 9.8 1.1 3.2 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat Orthopox_A5L PF06193.11 PRP75547.1 - 0.96 8.8 9.0 0.81 9.1 6.9 2.0 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like LPP PF04728.13 PRP75547.1 - 6 7.3 20.8 1 9.8 0.0 5.4 5 1 0 5 5 5 0 Lipoprotein leucine-zipper Nuc_sug_transp PF04142.15 PRP75548.1 - 6.1e-25 88.1 18.4 7.6e-25 87.7 18.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 PRP75548.1 - 0.25 11.5 24.4 0.027 14.6 8.2 2.5 2 1 0 2 2 2 0 EamA-like transporter family PPL5 PF18168.1 PRP75549.1 - 2.4 7.4 12.2 1.7 7.9 0.7 2.5 2 0 0 2 2 2 0 Prim-pol family 5 zf-C3HC4_3 PF13920.6 PRP75549.1 - 5.8 6.9 30.6 0.031 14.1 14.7 4.1 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M24 PF00557.24 PRP75550.1 - 3.7e-21 75.8 0.9 8.5e-21 74.6 1.2 1.4 2 0 0 2 2 2 1 Metallopeptidase family M24 PNGaseA PF12222.8 PRP75551.1 - 6.1e-108 361.5 0.4 8.3e-108 361.0 0.4 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A FAD_binding_1 PF00667.20 PRP75553.1 - 8.2e-60 202.1 0.0 1.2e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PRP75553.1 - 8.6e-35 120.0 0.8 1.6e-34 119.2 0.8 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 PRP75553.1 - 1.2e-16 61.3 0.0 4.2e-16 59.5 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 PRP75553.1 - 0.12 12.6 0.0 4.2 7.6 0.0 2.3 1 1 1 2 2 2 0 Flavodoxin domain MRPL52 PF18699.1 PRP75554.1 - 1.4e-12 47.7 0.1 1.7e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Mitoribosomal protein mL52 SWIM PF04434.17 PRP75555.1 - 6.5e-05 22.5 0.2 0.00018 21.1 0.2 1.8 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.6 PRP75555.1 - 0.0033 17.7 4.0 0.0033 17.7 4.0 2.9 2 0 0 2 2 2 1 Ring finger domain ZZ PF00569.17 PRP75555.1 - 0.015 15.1 10.1 0.015 15.1 10.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-C3HC4_3 PF13920.6 PRP75555.1 - 2.3 8.1 19.0 0.4 10.6 3.3 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 PRP75555.1 - 8.8 6.5 13.4 2.6e+03 -1.5 13.4 3.2 1 1 0 1 1 1 0 Double zinc ribbon ubiquitin PF00240.23 PRP75556.1 - 1.3e-05 24.8 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 PRP75557.1 - 3.5e-60 203.6 0.0 1.9e-59 201.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Ank_4 PF13637.6 PRP75557.1 - 4.1e-27 94.2 0.5 1.9e-09 37.9 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP75557.1 - 8.1e-27 93.6 1.1 6.4e-13 49.1 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 PRP75557.1 - 4e-25 88.6 0.0 1.1e-24 87.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DEP PF00610.21 PRP75557.1 - 1.7e-20 72.9 0.4 9.6e-20 70.4 0.1 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ank_5 PF13857.6 PRP75557.1 - 2.9e-19 68.9 0.4 5.8e-09 36.0 0.0 4.7 4 1 1 5 5 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75557.1 - 2.9e-16 57.9 1.1 0.0009 19.5 0.0 6.3 8 0 0 8 8 5 3 Ankyrin repeat Ank PF00023.30 PRP75557.1 - 1.9e-14 53.3 1.5 0.0052 17.2 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat Kinase-like PF14531.6 PRP75557.1 - 4e-06 26.4 0.0 7.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP75557.1 - 0.0061 15.9 0.1 0.013 14.9 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP75557.1 - 0.014 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 PRP75557.1 - 0.042 13.8 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinesin PF00225.23 PRP75558.1 - 9.1e-104 347.0 0.1 2.2e-103 345.7 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP75558.1 - 4.3e-23 81.9 0.0 8.4e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF1664 PF07889.12 PRP75558.1 - 0.0054 16.8 0.6 0.011 15.8 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) IstB_IS21 PF01695.17 PRP75558.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1522 PF07482.11 PRP75558.1 - 0.11 12.8 0.6 0.57 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) HEAT PF02985.22 PRP75560.1 - 0.044 14.1 0.0 6.9 7.2 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat Y2_Tnp PF04986.13 PRP75560.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Putative transposase PET10 PF17316.2 PRP75560.1 - 0.06 12.9 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Petite colonies protein 10 rve PF00665.26 PRP75562.1 - 1.5e-09 38.1 0.1 0.0017 18.5 0.0 3.5 2 1 1 3 3 3 2 Integrase core domain rve_3 PF13683.6 PRP75562.1 - 0.00028 20.6 0.3 0.09 12.6 0.1 2.6 2 0 0 2 2 2 2 Integrase core domain PSII_Pbs27 PF13326.6 PRP75562.1 - 0.00032 21.0 0.3 0.35 11.2 0.0 2.7 3 0 0 3 3 3 2 Photosystem II Pbs27 DpnI_C PF17726.1 PRP75562.1 - 0.0009 19.3 1.5 1.4 9.1 0.1 3.0 2 0 0 2 2 2 2 Dam-replacing HTH domain DUF5071 PF16804.5 PRP75562.1 - 0.0047 17.2 1.0 5.3 7.3 0.0 3.4 2 2 1 3 3 3 2 Domain of unknown function (DUF5071) DUF3874 PF12990.7 PRP75564.1 - 0.0091 16.3 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknonw function from B. Theta Gene description (DUF3874) CDC14 PF08045.11 PRP75567.1 - 0.019 14.1 1.2 0.029 13.5 1.2 1.2 1 0 0 1 1 1 0 Cell division control protein 14, SIN component APG6_N PF17675.1 PRP75568.1 - 0.018 15.6 18.2 0.025 15.1 18.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_11 PF13086.6 PRP75568.1 - 0.14 11.9 5.2 0.13 12.0 5.2 1.0 1 0 0 1 1 1 0 AAA domain Phage_TAC_4 PF08748.11 PRP75568.1 - 0.46 10.8 6.8 0.64 10.3 6.8 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone Pro_isomerase PF00160.21 PRP75569.1 - 5.2e-42 143.8 0.4 1.2e-41 142.6 0.4 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNF2_N PF00176.23 PRP75571.1 - 1.3e-70 237.9 1.4 2.4e-68 230.4 0.1 2.7 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP75571.1 - 1.1e-17 64.4 0.0 5.5e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT_2 PF13646.6 PRP75572.1 - 2.4e-31 108.0 0.2 4.5e-14 52.6 0.0 2.8 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 PRP75572.1 - 2.4e-23 80.4 0.0 0.00025 21.4 0.0 6.3 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 PRP75572.1 - 3.4e-15 54.9 0.0 0.1 12.9 0.0 5.7 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 PRP75572.1 - 1.2e-05 25.7 0.1 0.26 11.8 0.0 4.2 3 1 1 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 PRP75572.1 - 0.00016 21.7 0.4 2.8 7.9 0.0 4.1 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 PRP75572.1 - 0.0009 19.2 0.3 0.36 10.9 0.0 3.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Aconitase_B_N PF11791.8 PRP75572.1 - 0.0037 17.3 0.4 0.086 12.9 0.1 2.6 2 1 0 2 2 2 1 Aconitate B N-terminal domain Cohesin_HEAT PF12765.7 PRP75572.1 - 0.011 16.1 0.0 13 6.2 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SRP_TPR_like PF17004.5 PRP75572.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative TPR-like repeat MgtE_N PF03448.17 PRP75572.1 - 0.025 15.2 0.5 5.9 7.6 0.0 3.2 3 0 0 3 3 3 0 MgtE intracellular N domain Vitellogenin_N PF01347.22 PRP75572.1 - 0.04 12.3 0.1 1.9 6.8 0.0 2.6 2 1 1 3 3 3 0 Lipoprotein amino terminal region CART PF06373.11 PRP75572.1 - 0.25 11.6 1.5 0.68 10.2 0.3 2.3 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) Spc24 PF08286.11 PRP75573.1 - 1.4e-06 28.4 6.3 1.4e-06 28.4 6.3 1.7 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 BLI1 PF17324.2 PRP75573.1 - 0.0019 18.9 7.6 0.0032 18.1 7.6 1.4 1 0 0 1 1 1 1 BLOC-1 interactor 1 HAUS-augmin3 PF14932.6 PRP75573.1 - 0.0034 17.0 13.6 0.0053 16.4 13.5 1.3 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.19 PRP75573.1 - 0.0081 14.1 7.2 0.0098 13.9 7.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Allexi_40kDa PF05549.11 PRP75573.1 - 0.0095 15.5 4.7 0.013 15.0 4.7 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein MitMem_reg PF13012.6 PRP75573.1 - 0.048 14.1 3.1 0.096 13.1 2.9 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Fib_alpha PF08702.10 PRP75573.1 - 0.049 13.8 12.8 0.079 13.2 12.8 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Mito_fiss_reg PF05308.11 PRP75573.1 - 0.15 12.1 9.5 0.19 11.8 9.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4407 PF14362.6 PRP75573.1 - 0.22 10.8 10.7 0.34 10.2 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Noelin-1 PF12308.8 PRP75573.1 - 0.3 11.1 4.4 0.52 10.3 2.0 2.2 1 1 1 2 2 2 0 Neurogenesis glycoprotein FapA PF03961.13 PRP75573.1 - 0.41 9.2 9.1 0.49 8.9 9.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cluap1 PF10234.9 PRP75573.1 - 0.41 10.0 15.9 0.64 9.4 15.9 1.4 1 1 0 1 1 1 0 Clusterin-associated protein-1 GAS PF13851.6 PRP75573.1 - 0.58 9.5 18.9 0.52 9.6 15.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding XhlA PF10779.9 PRP75573.1 - 0.67 10.2 9.3 0.18 12.0 1.7 2.6 1 1 3 4 4 4 0 Haemolysin XhlA UPF0242 PF06785.11 PRP75573.1 - 0.97 9.5 12.8 1.4 9.0 12.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 PRP75573.1 - 1.1 7.7 3.0 1.6 7.1 3.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Macoilin PF09726.9 PRP75573.1 - 1.2 7.6 12.0 1.5 7.3 12.0 1.1 1 0 0 1 1 1 0 Macoilin family Seryl_tRNA_N PF02403.22 PRP75573.1 - 1.4 9.1 17.6 3.9 7.7 7.0 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N PF09177.11 PRP75573.1 - 1.5 9.4 10.9 1.3 9.6 7.7 2.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal APG6_N PF17675.1 PRP75573.1 - 2.3 8.7 19.1 4.7 7.7 18.3 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1525 PF07511.11 PRP75573.1 - 2.6 8.2 7.6 0.6 10.3 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1525) DUF948 PF06103.11 PRP75573.1 - 2.7 8.3 7.4 1.5 9.1 0.6 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 PRP75573.1 - 2.7 8.9 16.6 4.1 8.3 2.2 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 PRP75573.1 - 4.6 7.3 10.5 5 7.2 8.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 PRP75573.1 - 6 7.6 11.2 5.5 7.7 9.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Jnk-SapK_ap_N PF09744.9 PRP75573.1 - 8.1 6.6 19.8 17 5.6 16.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 LMBR1 PF04791.16 PRP75573.1 - 8.5 5.2 6.5 9.5 5.0 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ax_dynein_light PF10211.9 PRP75573.1 - 8.7 6.2 20.1 11 5.9 16.6 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain FeS_assembly_P PF01883.19 PRP75574.1 - 6.3e-14 51.9 0.0 1.6e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein DUF4200 PF13863.6 PRP75575.1 - 1.2e-33 116.0 20.2 1.2e-33 116.0 20.2 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 PRP75575.1 - 0.16 12.4 4.4 11 6.6 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF5063 PF16702.5 PRP75575.1 - 0.56 10.6 5.8 5.5 7.4 2.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5063) AAA_23 PF13476.6 PRP75575.1 - 0.8 10.2 28.9 0.064 13.8 10.3 2.4 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.6 PRP75575.1 - 3.4 7.0 15.4 0.24 10.7 7.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Rx_N PF18052.1 PRP75575.1 - 8.3 6.8 12.0 4 7.8 1.3 3.5 3 2 1 4 4 4 0 Rx N-terminal domain Z1 PF10593.9 PRP75576.1 - 5.3e-32 111.2 0.0 1.4e-31 109.8 0.0 1.7 1 0 0 1 1 1 1 Z1 domain LCAT PF02450.15 PRP75578.1 - 1.7e-05 24.2 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 PRP75578.1 - 0.049 14.2 0.0 0.061 13.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP75578.1 - 0.075 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 PRP75578.1 - 0.14 11.4 0.1 0.51 9.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) WD40 PF00400.32 PRP75581.1 - 2.8e-32 110.2 6.2 5.9e-09 36.4 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75581.1 - 6.3e-14 52.1 0.0 0.03 14.6 0.0 5.0 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP75581.1 - 0.00081 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain FPP PF05911.11 PRP75581.1 - 0.023 12.9 0.2 0.034 12.3 0.2 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil bZIP_1 PF00170.21 PRP75581.1 - 0.062 13.4 1.6 0.12 12.5 1.6 1.4 1 0 0 1 1 1 0 bZIP transcription factor KIAA1430 PF13879.6 PRP75581.1 - 0.66 10.8 2.9 0.57 11.0 1.1 1.8 2 0 0 2 2 2 0 KIAA1430 homologue Whirly PF08536.11 PRP75582.1 - 0.068 13.0 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Whirly transcription factor Rhv PF00073.20 PRP75583.1 - 0.058 13.0 0.1 0.14 11.7 0.1 1.6 1 1 0 1 1 1 0 picornavirus capsid protein Myosin_head PF00063.21 PRP75585.1 - 1.1e-32 113.1 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DUF87 PF01935.17 PRP75585.1 - 0.00041 20.5 0.1 0.00082 19.5 0.1 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain ABC_tran PF00005.27 PRP75585.1 - 0.0015 19.1 0.0 0.0021 18.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PRP75585.1 - 0.0015 18.9 0.1 0.0034 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PRP75585.1 - 0.0061 16.5 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 PRP75585.1 - 0.011 16.3 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PRP75585.1 - 0.014 15.7 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PRP75585.1 - 0.028 14.7 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PRP75585.1 - 0.032 13.7 0.0 0.071 12.6 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 PRP75585.1 - 0.036 14.4 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_6 PF12774.7 PRP75585.1 - 0.037 13.0 0.1 0.059 12.3 0.1 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Zeta_toxin PF06414.12 PRP75585.1 - 0.044 13.1 0.0 0.087 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 PRP75585.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PRP75585.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Hpr_kinase_C PF07475.12 PRP75585.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Rad17 PF03215.15 PRP75585.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain PWWP PF00855.17 PRP75586.1 - 8.7e-18 64.5 2.4 3.7e-17 62.5 2.4 2.2 1 0 0 1 1 1 1 PWWP domain DNA_ligase_A_M PF01068.21 PRP75586.1 - 3.5e-08 33.3 1.5 2e-06 27.6 0.0 3.1 2 1 1 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PRP75586.1 - 0.0089 16.4 0.2 3.7 7.9 0.0 3.2 3 0 0 3 3 3 2 DNA ligase N terminus SNF2_N PF00176.23 PRP75589.1 - 1.9e-12 46.6 0.0 4.2e-12 45.5 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 PRP75589.1 - 1.2e-10 41.1 0.0 2.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RNA_pol_Rpb1_5 PF04998.17 PRP75590.1 - 4.1e-17 62.5 0.5 1.4e-11 44.4 0.3 2.1 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 PRP75590.1 - 1e-09 38.5 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 PRP75590.1 - 8.1e-08 32.3 2.4 0.0003 20.8 0.5 2.3 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_2 PF00623.20 PRP75591.1 - 2.1e-18 67.1 0.1 4.8e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 PRP75591.1 - 1.4e-11 44.4 0.7 2.5e-11 43.5 0.7 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 PRP75591.1 - 3e-10 40.3 0.1 4.9e-07 29.8 0.1 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 3 p31comet PF06581.12 PRP75595.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding WD40 PF00400.32 PRP75597.1 - 2.3e-09 37.7 0.0 0.85 10.6 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat SAP PF02037.27 PRP75597.1 - 1.3e-06 28.0 0.0 3.8e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 SAP domain ANAPC4_WD40 PF12894.7 PRP75597.1 - 4.7e-05 23.6 0.0 14 6.1 0.0 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SUI1 PF01253.22 PRP75598.1 - 7e-22 77.7 0.0 3.4e-21 75.5 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 PRP75598.1 - 1.3e-10 41.8 0.0 1.3e-10 41.8 0.0 2.8 4 0 0 4 4 4 1 Pre-PUA-like domain Kin17_mid PF10357.9 PRP75598.1 - 0.0033 17.3 0.2 0.069 13.1 0.1 2.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein PUA PF01472.20 PRP75598.1 - 0.031 14.2 0.1 0.19 11.7 0.0 2.4 2 1 0 2 2 2 0 PUA domain ubiquitin PF00240.23 PRP75599.1 - 3.8e-05 23.4 0.0 8.2e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 PRP75599.1 - 0.00057 20.0 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like EF-hand_1 PF00036.32 PRP75599.1 - 0.045 13.3 3.0 0.063 12.9 0.1 2.6 2 0 0 2 2 2 0 EF hand Phospholip_B PF04916.13 PRP75601.1 - 0.076 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Phospholipase B SAP PF02037.27 PRP75601.1 - 0.081 12.7 0.8 0.18 11.6 0.8 1.6 1 0 0 1 1 1 0 SAP domain Pkinase_Tyr PF07714.17 PRP75611.1 - 1.6e-39 135.7 0.1 2.6e-39 135.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75611.1 - 4e-30 105.1 0.1 7e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP75611.1 - 4.9e-07 30.2 3.6 4.9e-07 30.2 3.6 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif EphA2_TM PF14575.6 PRP75611.1 - 0.024 15.5 0.5 0.073 14.0 0.5 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF5329 PF17263.2 PRP75611.1 - 0.23 11.7 1.5 7.4 6.8 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5329) DUF347 PF03988.12 PRP75611.1 - 3.6 7.8 6.5 2 8.7 3.5 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) cobW PF02492.19 PRP75612.1 - 5.8e-57 192.1 0.9 9.1e-57 191.5 0.9 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PRP75612.1 - 6.9e-21 74.0 0.0 1.8e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 PRP75612.1 - 3.5e-05 23.8 0.3 0.2 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP75612.1 - 0.0052 16.3 0.1 0.91 9.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 PRP75612.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 PRP75612.1 - 0.037 14.0 0.0 0.097 12.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 PRP75612.1 - 0.052 13.3 0.0 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 PRP75612.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 PRP75612.1 - 0.15 12.6 0.0 9.3 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PRP75612.1 - 0.16 12.0 0.1 0.59 10.2 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase TGT PF01702.18 PRP75614.1 - 5.3e-92 308.7 0.0 4.3e-64 216.9 0.0 2.0 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase Homeodomain PF00046.29 PRP75615.1 - 3.7e-24 84.3 19.6 9.1e-06 25.4 0.2 8.1 7 1 1 8 8 8 6 Homeodomain Homeobox_KN PF05920.11 PRP75615.1 - 4.5e-11 42.5 5.3 0.17 11.8 0.0 6.9 6 1 0 6 6 6 4 Homeobox KN domain HTH_28 PF13518.6 PRP75615.1 - 0.0079 16.3 4.9 41 4.4 0.1 5.4 5 0 0 5 5 5 0 Helix-turn-helix domain DUF1510 PF07423.11 PRP75615.1 - 0.03 14.5 6.2 0.56 10.4 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1510) Homez PF11569.8 PRP75615.1 - 0.046 13.2 6.4 4.2 6.9 0.0 4.9 6 0 0 6 6 6 0 Homeodomain leucine-zipper encoding, Homez HTH_23 PF13384.6 PRP75615.1 - 0.057 13.2 3.9 34 4.4 0.0 4.3 4 0 0 4 4 4 0 Homeodomain-like domain DUF746 PF05344.11 PRP75615.1 - 0.18 11.7 0.3 12 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) SPT16 PF08644.11 PRP75615.1 - 0.27 11.4 2.1 0.95 9.6 2.1 1.9 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Terminase_5 PF06056.12 PRP75615.1 - 1.2 9.0 6.1 16 5.5 0.0 4.3 5 0 0 5 5 5 0 Putative ATPase subunit of terminase (gpP-like) Foie-gras_1 PF11817.8 PRP75617.1 - 1.3e-36 126.5 3.6 2.2e-36 125.8 3.6 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 PRP75617.1 - 8.8e-05 22.4 0.0 0.00022 21.2 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Transglut_C PF00927.22 PRP75617.1 - 0.017 15.2 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain DUF5618 PF18498.1 PRP75617.1 - 0.032 14.4 1.6 0.41 10.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) Amidohydro_2 PF04909.14 PRP75618.1 - 3.7e-64 217.3 0.1 4.6e-64 217.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase EGF_2 PF07974.13 PRP75618.1 - 8.2e-06 26.1 42.6 0.00078 19.8 10.6 4.0 3 0 0 3 3 3 2 EGF-like domain EGF PF00008.27 PRP75618.1 - 0.0044 17.3 7.4 0.0044 17.3 7.4 4.2 4 0 0 4 4 4 3 EGF-like domain RIIa PF02197.17 PRP75619.1 - 0.029 14.0 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Acetyltransf_3 PF13302.7 PRP75620.1 - 1.4e-08 35.5 0.0 1.7e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP75620.1 - 0.00051 20.3 0.0 0.00068 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3430 PF11912.8 PRP75621.1 - 3.4e-05 24.0 0.2 6e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Oxidored_FMN PF00724.20 PRP75622.1 - 1.9e-99 333.2 0.0 2.2e-99 333.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF4064 PF13273.6 PRP75623.1 - 0.00041 20.6 2.5 0.0034 17.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) DUF2207 PF09972.9 PRP75623.1 - 0.0016 17.3 0.1 0.0016 17.3 0.1 2.0 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) CBP_BcsF PF11120.8 PRP75623.1 - 4.3 7.5 7.3 13 6.0 0.0 3.5 2 1 1 3 3 3 0 Cellulose biosynthesis protein BcsF Symplekin_C PF12295.8 PRP75624.1 - 1.2e-47 162.4 2.6 1.2e-47 162.4 2.6 2.7 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 PRP75624.1 - 5.5e-08 32.7 3.9 1.4e-07 31.4 1.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.6 PRP75624.1 - 0.0054 17.1 0.2 0.48 10.9 0.0 3.0 2 0 0 2 2 2 1 HEAT repeats SoDot-IcmSS PF16848.5 PRP75624.1 - 0.025 14.6 0.1 0.074 13.0 0.1 1.8 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative TRAP_alpha PF03896.16 PRP75626.1 - 8.7e-33 113.7 0.1 1e-32 113.5 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit MFS_Mycoplasma PF07672.13 PRP75626.1 - 0.007 15.7 0.0 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 Mycoplasma MFS transporter HEAT_EZ PF13513.6 PRP75627.1 - 1.1e-05 25.8 0.0 0.00072 20.0 0.0 3.1 2 0 0 2 2 2 1 HEAT-like repeat Arm PF00514.23 PRP75627.1 - 0.00049 20.0 0.0 0.01 15.8 0.0 3.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PRP75627.1 - 0.0005 20.1 1.2 0.01 16.0 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 PRP75627.1 - 0.095 13.1 0.0 0.58 10.6 0.0 2.4 3 0 0 3 3 3 0 HEAT repeats Cohesin_HEAT PF12765.7 PRP75627.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion DUF155 PF02582.14 PRP75627.1 - 0.14 12.3 0.7 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 PRK PF00485.18 PRP75628.1 - 2.4e-10 40.5 0.0 4.9e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 PRP75628.1 - 1.1e-05 26.0 0.0 1.9e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 PRP75628.1 - 0.00031 19.8 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 PRP75628.1 - 0.00067 20.1 1.0 0.024 15.1 1.0 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP75628.1 - 0.0011 18.3 0.2 0.0021 17.3 0.1 1.5 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.22 PRP75628.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.6 PRP75628.1 - 0.0015 18.7 0.0 0.019 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP75628.1 - 0.0018 18.6 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PRP75628.1 - 0.0025 18.1 0.0 0.0034 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 PRP75628.1 - 0.0041 17.3 0.1 1.5 9.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_24 PF13479.6 PRP75628.1 - 0.0047 16.7 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 PRP75628.1 - 0.067 13.6 0.1 0.1 13.1 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 PRP75628.1 - 0.074 13.1 0.1 0.09 12.8 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 PRP75628.1 - 0.076 12.9 0.1 0.25 11.3 0.1 1.8 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 PRP75628.1 - 0.078 12.2 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 PRP75628.1 - 0.089 13.1 0.3 0.1 12.9 0.3 1.5 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 PRP75628.1 - 0.097 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.22 PRP75628.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 PRP75628.1 - 0.13 12.2 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 PRP75628.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PRP75628.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 PRP75628.1 - 0.2 11.3 0.6 1.6 8.4 0.1 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase Cullin PF00888.22 PRP75629.1 - 2.9e-199 663.7 7.9 2.9e-199 663.7 7.9 2.7 3 0 0 3 3 3 1 Cullin family Cullin_Nedd8 PF10557.9 PRP75629.1 - 9.8e-24 83.2 2.0 3e-23 81.6 0.6 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain Cas_Cas5d PF09704.10 PRP75629.1 - 0.013 15.4 0.6 0.029 14.2 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas5) PLAC8 PF04749.17 PRP75630.1 - 8.8e-11 42.7 12.7 8.8e-11 42.7 12.7 2.9 2 2 0 2 2 2 1 PLAC8 family SET PF00856.28 PRP75630.1 - 5.6e-09 36.6 0.0 1.2e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 PRP75630.1 - 6.4e-06 26.2 13.5 6.4e-06 26.2 13.5 4.1 3 1 0 3 3 3 1 MYND finger RNA_pol_Rpc34 PF05158.12 PRP75631.1 - 1.3e-59 202.3 7.6 1e-41 143.4 1.1 2.9 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 PRP75631.1 - 3.4e-06 27.1 0.6 8e-06 25.9 0.6 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TFIIE_alpha PF02002.17 PRP75631.1 - 0.00013 21.7 1.7 0.0043 16.9 0.2 2.5 1 1 1 2 2 2 1 TFIIE alpha subunit PadR PF03551.14 PRP75631.1 - 0.0054 16.7 0.5 0.022 14.7 0.1 2.3 2 1 0 2 2 2 1 Transcriptional regulator PadR-like family TrmB PF01978.19 PRP75631.1 - 0.0081 16.0 0.3 0.078 12.9 0.1 2.7 2 1 1 3 3 3 1 Sugar-specific transcriptional regulator TrmB RPA_C PF08784.11 PRP75631.1 - 0.0096 16.6 0.4 2.5 8.8 0.1 2.4 2 0 0 2 2 2 1 Replication protein A C terminal MarR PF01047.22 PRP75631.1 - 0.02 14.8 0.8 0.19 11.7 0.1 2.7 2 1 1 3 3 3 0 MarR family Rrf2 PF02082.20 PRP75631.1 - 0.061 13.7 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator DUF1690 PF07956.11 PRP75631.1 - 0.076 13.4 0.6 0.15 12.5 0.6 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Cdc6_C PF09079.11 PRP75631.1 - 0.12 12.4 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain TFA2_Winged_2 PF18121.1 PRP75631.1 - 0.77 9.5 3.0 2.9 7.7 0.1 3.1 3 1 0 3 3 3 0 TFA2 Winged helix domain 2 Helicase_C PF00271.31 PRP75632.1 - 3.6e-15 56.3 0.0 1.6e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP75632.1 - 1.7e-14 53.9 0.0 5.3e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.10 PRP75632.1 - 7.1e-13 48.3 0.1 1.8e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 PRP75632.1 - 1.6e-12 48.0 5.3 6.7e-12 46.0 5.3 2.2 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 PRP75632.1 - 3e-12 46.4 0.0 7.4e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 HRDC domain zf-CCHC PF00098.23 PRP75632.1 - 4e-06 26.6 2.5 4e-06 26.6 2.5 1.9 2 0 0 2 2 2 1 Zinc knuckle DUF87 PF01935.17 PRP75632.1 - 0.00025 21.2 5.9 0.0019 18.3 1.6 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain SLATT_4 PF18186.1 PRP75632.1 - 0.063 12.9 1.0 0.18 11.4 1.0 1.7 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 MscS_porin PF12795.7 PRP75632.1 - 2.5 7.6 12.1 0.25 10.8 7.4 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain LRR_6 PF13516.6 PRP75633.1 - 3.5e-16 57.8 8.8 0.69 10.1 0.0 9.1 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 PRP75633.1 - 5.3e-09 36.2 7.1 0.01 16.2 0.0 6.3 6 1 3 9 9 9 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP75633.1 - 4.2e-05 23.5 4.4 13 6.8 0.0 6.8 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 PRP75633.1 - 8.4e-05 22.3 9.1 0.05 13.4 0.1 5.7 3 2 1 4 4 4 3 Leucine rich repeat ATP_bind_1 PF03029.17 PRP75634.1 - 1e-77 261.2 0.1 1.7e-77 260.5 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PRP75634.1 - 8.6e-05 23.1 0.0 0.87 10.1 0.1 2.8 3 0 0 3 3 3 2 AAA domain GTP_EFTU PF00009.27 PRP75634.1 - 0.00012 21.7 0.0 0.0023 17.5 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 PRP75634.1 - 0.00014 21.1 1.9 0.00017 20.8 0.0 2.1 3 0 0 3 3 3 1 NB-ARC domain MMR_HSR1 PF01926.23 PRP75634.1 - 0.0002 21.4 0.0 0.0009 19.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PRP75634.1 - 0.00027 21.4 0.0 0.00063 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 PRP75634.1 - 0.00039 21.0 0.4 0.1 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP75634.1 - 0.0004 20.2 0.0 0.00078 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PRP75634.1 - 0.00062 19.7 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 PRP75634.1 - 0.00073 19.8 0.0 0.06 13.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 PRP75634.1 - 0.002 17.5 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 PRP75634.1 - 0.0049 16.6 2.3 1 9.0 0.0 3.1 3 0 0 3 3 3 1 Thymidylate kinase AAA_33 PF13671.6 PRP75634.1 - 0.006 16.7 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain FeoB_N PF02421.18 PRP75634.1 - 0.0063 16.1 0.0 0.065 12.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.19 PRP75634.1 - 0.0095 15.5 0.0 0.47 10.0 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 PRP75634.1 - 0.013 15.3 0.1 0.042 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 PRP75634.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 PRP75634.1 - 0.014 15.0 0.0 0.073 12.7 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 PRP75634.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain G-alpha PF00503.20 PRP75634.1 - 0.015 14.5 0.3 2.1 7.4 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit APS_kinase PF01583.20 PRP75634.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ATPase_2 PF01637.18 PRP75634.1 - 0.026 14.4 0.3 0.092 12.6 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MeaB PF03308.16 PRP75634.1 - 0.046 12.7 0.0 7.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Adeno_IVa2 PF02456.15 PRP75634.1 - 0.05 12.4 0.0 1.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein CbiA PF01656.23 PRP75634.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 PRP75634.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF87 PF01935.17 PRP75634.1 - 0.084 13.0 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 PRP75634.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 PRP75634.1 - 0.11 12.5 0.8 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP75634.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PRP75634.1 - 0.15 12.6 0.0 0.49 10.9 0.0 1.9 2 0 0 2 2 1 0 ABC transporter PAN_4 PF14295.6 PRP75636.1 - 2.4e-08 33.8 3.0 2.4e-08 33.8 3.0 2.1 2 0 0 2 2 2 1 PAN domain Glyco_hydro_16 PF00722.21 PRP75636.1 - 3.3e-08 33.2 0.0 6.5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 PRP75636.1 - 0.0022 16.5 0.0 0.0032 15.9 0.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PAN_1 PF00024.26 PRP75636.1 - 0.016 15.1 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 PAN domain PLAC8 PF04749.17 PRP75637.1 - 4.8e-18 66.0 17.5 6.4e-18 65.6 17.5 1.2 1 0 0 1 1 1 1 PLAC8 family Fer2_3 PF13085.6 PRP75639.1 - 1.3e-31 108.8 0.0 2.2e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 PRP75639.1 - 2.8e-09 37.3 6.9 2.8e-09 37.3 6.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 PRP75639.1 - 5.7e-09 36.4 5.0 5.7e-09 36.4 5.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 PRP75639.1 - 2.5e-07 30.7 3.4 2.5e-07 30.7 3.4 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 PRP75639.1 - 0.00071 19.8 0.7 0.37 11.0 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 PRP75639.1 - 0.0022 17.9 3.1 0.033 14.2 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 PRP75639.1 - 0.43 10.8 15.1 0.79 9.9 10.2 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 PRP75639.1 - 1.1 9.9 17.2 0.058 14.0 9.1 2.8 2 2 1 3 3 3 0 4Fe-4S dicluster domain Peptidase_A22B PF04258.13 PRP75640.1 - 4.6e-19 69.0 4.2 1e-18 67.9 4.2 1.6 1 0 0 1 1 1 1 Signal peptide peptidase Chlam_PMP PF02415.17 PRP75640.1 - 0.3 11.7 68.6 1.7 9.3 0.0 12.6 12 1 0 12 12 12 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat JmjC PF02373.22 PRP75641.1 - 9.5e-07 29.2 0.1 4.1e-06 27.2 0.1 2.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Molybdopterin_N PF18364.1 PRP75642.1 - 0.02 14.9 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain GNT-I PF03071.15 PRP75643.1 - 2.1e-114 382.7 0.3 2.5e-114 382.4 0.3 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_tranf_2_3 PF13641.6 PRP75643.1 - 3.6e-09 36.9 0.2 8e-08 32.4 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PRP75643.1 - 2.5e-06 27.4 0.5 0.0007 19.4 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Stealth_CR3 PF17102.5 PRP75643.1 - 0.059 13.3 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 BOP1NT PF08145.12 PRP75644.1 - 1.9e-62 211.6 14.0 1.9e-62 211.6 14.0 2.0 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 PRP75644.1 - 2.9e-29 100.7 11.7 1.8e-09 38.1 0.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75644.1 - 5.6e-10 39.4 0.0 0.012 15.9 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP75644.1 - 0.012 14.4 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like PfkB PF00294.24 PRP75645.1 - 3.1e-29 102.3 4.6 4.9e-14 52.3 0.2 2.1 1 1 0 2 2 2 2 pfkB family carbohydrate kinase ETF PF01012.21 PRP75645.1 - 0.0087 16.0 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ABC2_membrane PF01061.24 PRP75646.1 - 1.1e-90 302.7 62.4 8.4e-48 162.6 21.1 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 PRP75646.1 - 6.8e-40 136.8 0.0 2.3e-20 73.5 0.0 3.1 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 PRP75646.1 - 1.2e-26 92.4 0.5 5.1e-24 84.0 0.0 3.9 4 0 0 4 4 4 2 CDR ABC transporter RsgA_GTPase PF03193.16 PRP75646.1 - 1e-06 28.7 0.1 0.00067 19.6 0.1 2.7 3 0 0 3 3 3 1 RsgA GTPase ABC_trans_N PF14510.6 PRP75646.1 - 1.1e-06 29.2 0.1 4.2e-06 27.3 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 PRP75646.1 - 2.3e-06 27.0 16.5 2.3e-06 27.0 16.5 3.8 3 2 1 4 4 4 1 ABC-2 family transporter protein AAA_16 PF13191.6 PRP75646.1 - 8.8e-06 26.2 0.0 0.053 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 PRP75646.1 - 9.8e-06 25.2 0.1 0.0047 16.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PRP75646.1 - 2.7e-05 24.2 0.1 0.12 12.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 PRP75646.1 - 0.00071 19.2 0.1 0.0032 17.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PRP75646.1 - 0.00079 18.8 0.0 0.036 13.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 PRP75646.1 - 0.00085 19.6 0.1 0.18 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PRP75646.1 - 0.0021 18.6 0.0 0.11 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PRP75646.1 - 0.0054 16.8 0.3 4.9 7.3 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 PRP75646.1 - 0.0062 16.7 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF3600 PF12207.8 PRP75646.1 - 0.015 15.2 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) AAA_30 PF13604.6 PRP75646.1 - 0.028 14.1 2.1 2.2 8.0 1.0 2.4 2 0 0 2 2 2 0 AAA domain CNP_C_terminal PF17839.1 PRP75646.1 - 0.036 14.8 0.5 0.58 10.9 0.1 3.1 2 1 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase cobW PF02492.19 PRP75646.1 - 0.085 12.4 0.2 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 PRP75646.1 - 0.089 13.0 3.0 0.31 11.3 1.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PRP75646.1 - 0.25 11.7 0.9 16 6.0 0.3 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PRP75646.1 - 0.28 11.1 1.2 7 6.5 0.6 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 PRP75646.1 - 0.37 11.3 3.5 0.95 9.9 0.3 2.6 2 0 0 2 2 2 0 AAA domain NUDIX PF00293.28 PRP75647.1 - 3.7e-14 52.9 0.1 4.5e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PRP75647.1 - 0.003 17.5 0.2 0.015 15.3 0.2 1.9 1 1 0 1 1 1 1 NUDIX domain Gla PF00594.20 PRP75647.1 - 0.042 14.1 0.5 0.082 13.1 0.5 1.4 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain LRR_8 PF13855.6 PRP75649.1 - 1e-40 137.3 58.9 7e-10 38.5 6.0 8.4 8 0 0 8 8 8 5 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP75649.1 - 4.2e-29 101.6 0.1 8e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP75649.1 - 4.7e-25 87.2 67.6 7.3e-06 26.2 2.8 10.4 6 3 2 9 9 9 7 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP75649.1 - 9.3e-22 77.6 0.1 1.6e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain MRG PF05712.13 PRP75649.1 - 4.3e-18 65.4 0.5 9.3e-18 64.2 0.5 1.5 1 0 0 1 1 1 1 MRG LRR_1 PF00560.33 PRP75649.1 - 5.1e-17 59.8 60.5 0.0045 17.3 0.8 16.1 16 1 0 16 16 16 8 Leucine Rich Repeat GPS PF01825.21 PRP75649.1 - 8.8e-10 39.0 4.6 2.6e-09 37.5 4.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Tudor-knot PF11717.8 PRP75649.1 - 4.8e-09 36.0 0.3 1.1e-08 34.9 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 PRP75649.1 - 0.09 12.7 0.9 0.21 11.5 0.9 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain LRR_9 PF14580.6 PRP75649.1 - 4 6.9 10.1 0.87 9.1 0.5 3.8 2 1 2 4 4 4 0 Leucine-rich repeat C2 PF00168.30 PRP75650.1 - 7.4e-05 23.0 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain DAGK_cat PF00781.24 PRP75653.1 - 3.1e-08 33.3 0.0 1e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3894 PF13033.6 PRP75653.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) RhoGEF PF00621.20 PRP75654.1 - 5.7e-43 147.3 0.0 1.6e-36 126.3 0.0 2.6 2 0 0 2 2 2 2 RhoGEF domain PH_13 PF16652.5 PRP75654.1 - 0.0015 18.3 0.3 0.01 15.6 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 PRP75654.1 - 0.012 15.9 0.8 0.031 14.6 0.2 1.9 2 0 0 2 2 2 0 Plant pleckstrin homology-like region IQ PF00612.27 PRP75654.1 - 0.02 14.6 1.8 0.024 14.4 0.4 1.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif PH PF00169.29 PRP75654.1 - 0.064 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 PH domain Band_7 PF01145.25 PRP75655.1 - 4.4e-07 30.1 0.1 1e-06 28.9 0.1 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family MVP_shoulder PF11978.8 PRP75655.1 - 2e-05 24.6 0.4 4.2e-05 23.6 0.4 1.6 1 1 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 PRP75655.1 - 0.057 13.5 0.7 0.23 11.5 0.1 2.3 2 1 1 3 3 3 0 Major Vault Protein Repeat domain Chorismate_synt PF01264.21 PRP75655.1 - 0.14 10.8 1.9 0.78 8.4 1.9 1.9 1 1 0 1 1 1 0 Chorismate synthase VWD PF00094.25 PRP75656.1 - 0.012 15.9 2.5 0.02 15.1 1.9 1.5 1 1 1 2 2 2 0 von Willebrand factor type D domain ABC2_membrane PF01061.24 PRP75657.1 - 2.9e-08 33.4 4.2 2.9e-08 33.4 4.2 1.4 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 PRP75657.1 - 0.00036 20.4 0.1 0.00036 20.4 0.1 1.6 2 0 0 2 2 2 1 CDR ABC transporter FERM_M PF00373.18 PRP75658.1 - 2.7e-21 76.1 0.0 4.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 FERM central domain FERM_f0 PF16511.5 PRP75658.1 - 3.7e-21 75.2 0.0 1.9e-15 56.9 0.0 2.4 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 PRP75658.1 - 7.4e-09 35.4 0.0 5.4e-06 26.3 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain ACBP PF00887.19 PRP75658.1 - 9.3e-05 22.6 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Kindlin_2_N PF18124.1 PRP75658.1 - 0.03 14.5 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Kindlin-2 N-terminal domain ubiquitin PF00240.23 PRP75658.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin family DUF971 PF06155.12 PRP75659.1 - 1.8e-23 83.0 0.0 2.8e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF971) ATG16 PF08614.11 PRP75660.1 - 1.1e-34 120.4 25.3 2e-34 119.6 25.3 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 PRP75660.1 - 5.7e-34 115.6 11.4 8.5e-08 32.7 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75660.1 - 1.7e-09 37.8 3.4 0.094 13.0 0.0 6.6 3 1 5 8 8 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP75660.1 - 1.3e-05 24.1 7.3 0.37 9.4 0.0 5.1 1 1 4 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.11 PRP75660.1 - 1.9e-05 24.6 0.1 0.018 14.9 0.0 3.5 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PRP75660.1 - 0.00022 20.7 0.0 0.037 13.4 0.0 3.2 2 1 0 2 2 2 1 WD40-like domain Cytochrom_D1 PF02239.16 PRP75660.1 - 0.0035 15.9 0.1 0.2 10.1 0.0 2.5 1 1 1 2 2 2 1 Cytochrome D1 heme domain Tropomyosin PF00261.20 PRP75660.1 - 0.0092 15.4 10.2 0.0092 15.4 10.2 2.9 1 1 2 3 3 3 1 Tropomyosin CALCOCO1 PF07888.11 PRP75660.1 - 0.012 14.5 22.4 0.017 14.0 22.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BST2 PF16716.5 PRP75660.1 - 0.021 15.4 4.6 0.021 15.4 4.6 3.4 2 2 1 3 3 3 0 Bone marrow stromal antigen 2 Kelch_6 PF13964.6 PRP75660.1 - 0.071 13.4 0.1 0.59 10.5 0.0 2.3 2 0 0 2 2 2 0 Kelch motif DUF1921 PF09081.10 PRP75660.1 - 0.11 12.7 0.0 0.59 10.4 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) Angiomotin_C PF12240.8 PRP75660.1 - 0.23 11.0 18.9 0.037 13.6 7.3 2.7 1 1 1 2 2 2 0 Angiomotin C terminal ERM PF00769.19 PRP75660.1 - 0.28 11.0 26.2 0.018 14.8 19.0 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Golgin_A5 PF09787.9 PRP75660.1 - 0.47 9.9 26.0 0.79 9.1 26.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 HAP1_N PF04849.13 PRP75660.1 - 0.82 8.8 28.0 1 8.5 7.6 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Tropomyosin_1 PF12718.7 PRP75660.1 - 0.9 9.7 30.6 3.4 7.8 5.6 2.8 1 1 1 2 2 2 0 Tropomyosin like DUF724 PF05266.14 PRP75660.1 - 1.5 8.6 28.4 0.66 9.8 10.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CobA_CobO_BtuR PF02572.15 PRP75660.1 - 2.2 8.5 9.1 8.4 6.6 8.2 2.4 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP CENP-H PF05837.12 PRP75660.1 - 5.7 7.4 28.3 0.35 11.3 4.7 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Fez1 PF06818.15 PRP75660.1 - 7.8 6.9 27.3 3.6 8.0 13.7 2.3 1 1 1 2 2 2 0 Fez1 DUF3449 PF11931.8 PRP75661.1 - 1.1e-70 237.1 11.2 1.3e-69 233.7 5.1 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF3449) SF3A3 PF16837.5 PRP75661.1 - 2.3e-19 69.7 4.3 3.1e-19 69.3 2.2 2.3 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 PRP75661.1 - 1.3e-09 38.1 4.9 5.2e-06 26.7 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SF3a60_bindingd PF12108.8 PRP75661.1 - 3e-09 36.6 1.5 4.3e-09 36.1 0.1 2.0 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 PRP75661.1 - 1.5e-08 34.7 5.6 4.1e-08 33.3 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PRP75661.1 - 0.0018 18.6 5.6 0.052 13.9 0.1 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 PRP75661.1 - 0.014 16.2 2.3 3.2 8.9 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 PRP75661.1 - 0.078 12.8 0.3 0.078 12.8 0.3 1.9 2 0 0 2 2 2 0 U1 zinc finger zf-Mss51 PF13824.6 PRP75661.1 - 0.13 12.4 0.1 0.45 10.6 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_3rep PF18868.1 PRP75661.1 - 0.16 12.6 0.9 17 6.1 0.1 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 PRP75661.1 - 7.2 6.6 5.9 1.4 9.0 0.5 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ABC_tran PF00005.27 PRP75663.1 - 3e-39 134.6 13.5 1.4e-19 70.9 0.0 4.9 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 PRP75663.1 - 5.1e-13 49.5 25.6 2.9e-05 24.0 0.1 6.2 6 0 0 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PRP75663.1 - 1.3e-06 28.0 0.0 0.02 14.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 PRP75663.1 - 0.0008 19.4 13.2 0.0008 19.4 13.2 6.1 4 1 0 4 4 2 1 ABC transporter RsgA_GTPase PF03193.16 PRP75663.1 - 0.0011 18.8 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP75663.1 - 0.0064 16.6 0.4 4.4 7.4 0.1 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PRP75663.1 - 0.0072 16.7 6.1 0.27 11.6 0.1 3.4 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 PRP75663.1 - 0.0073 16.6 0.1 4 7.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 PRP75663.1 - 0.016 15.6 0.3 4.9 7.6 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PRP75663.1 - 0.035 13.7 0.0 12 5.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 PRP75663.1 - 0.096 12.6 0.2 12 5.8 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 PRP75663.1 - 0.16 12.5 0.0 0.16 12.5 0.0 8.2 4 2 2 6 6 3 0 AAA domain AAA_15 PF13175.6 PRP75663.1 - 1.9 8.1 0.0 1.9 8.1 0.0 6.1 3 1 2 5 5 3 0 AAA ATPase domain AAA_33 PF13671.6 PRP75663.1 - 6.7 6.9 8.6 6.4 6.9 0.1 3.6 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 PRP75663.1 - 8.8 6.6 7.7 3.9 7.8 0.3 3.7 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit G8 PF10162.9 PRP75664.1 - 1.7e-18 66.9 0.2 4.2e-18 65.6 0.1 1.7 2 0 0 2 2 2 1 G8 domain Beta_helix PF13229.6 PRP75664.1 - 0.0084 16.0 4.8 0.0084 16.0 4.8 2.7 2 1 0 2 2 2 1 Right handed beta helix region GPS PF01825.21 PRP75665.1 - 2.8e-11 43.8 6.2 6.9e-11 42.5 6.2 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP75665.1 - 7.3e-07 28.7 1.0 4.7e-05 22.8 1.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75665.1 - 2.1e-05 24.0 0.5 0.00017 21.1 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP75666.1 - 8.3e-11 42.2 6.5 8.3e-11 42.2 6.5 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP75666.1 - 3.8e-07 30.3 9.7 0.0043 17.4 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP75666.1 - 3.2e-06 26.6 0.5 5.9e-05 22.5 0.5 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP75666.1 - 1.6e-05 24.5 10.1 0.00041 20.0 3.1 4.3 2 1 2 4 4 4 2 Leucine rich repeat LRRNT_2 PF08263.12 PRP75666.1 - 0.005 17.1 2.1 0.017 15.4 2.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Atrophin-1 PF03154.15 PRP75666.1 - 0.23 9.7 3.3 0.34 9.2 3.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family LRR_1 PF00560.33 PRP75666.1 - 0.73 10.6 6.7 40 5.3 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat Mucin PF01456.17 PRP75666.1 - 4.8 7.2 41.7 0.052 13.5 33.5 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein BACK PF07707.15 PRP75667.1 - 4.7e-05 23.4 0.0 0.00014 21.9 0.0 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch zf-MIZ PF02891.20 PRP75668.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger NUDIX PF00293.28 PRP75669.1 - 2.2e-21 76.3 0.1 3.5e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain PBP_like PF12727.7 PRP75669.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain PAN_4 PF14295.6 PRP75671.1 - 1.1e-05 25.2 7.0 1.1e-05 25.2 7.0 3.5 2 1 1 3 3 3 1 PAN domain Chitin_bind_1 PF00187.19 PRP75671.1 - 1.6e-05 25.3 21.5 1.6e-05 25.3 21.5 3.4 3 0 0 3 3 3 1 Chitin recognition protein PAN_2 PF08276.11 PRP75671.1 - 0.017 15.2 5.1 0.017 15.2 5.1 2.3 2 1 0 2 2 2 0 PAN-like domain GPS PF01825.21 PRP75673.1 - 1.2e-10 41.7 6.2 1.2e-10 41.7 6.2 3.2 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP75673.1 - 5e-09 35.8 0.1 3.8e-08 33.0 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75673.1 - 3.9e-08 33.0 0.0 1.3e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP75673.1 - 9.1e-05 22.1 0.5 0.87 9.4 0.5 4.6 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 PRP75673.1 - 0.0058 17.0 3.9 22 5.7 0.1 5.4 6 1 2 8 8 8 1 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PRP75673.1 - 0.014 15.6 2.7 0.043 14.1 2.7 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain ELK PF03789.13 PRP75674.1 - 0.062 13.4 0.9 4.1 7.6 0.0 2.8 3 0 0 3 3 3 0 ELK domain 7tm_6 PF02949.20 PRP75674.1 - 0.23 10.5 0.1 0.27 10.3 0.1 1.0 1 0 0 1 1 1 0 7tm Odorant receptor Phage_Mu_Gam PF07352.12 PRP75676.1 - 0.19 11.6 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein ExsD PF16806.5 PRP75680.1 - 0.057 13.3 1.7 0.081 12.8 0.5 1.9 2 0 0 2 2 2 0 Antiactivator protein ExsD FadA PF09403.10 PRP75681.1 - 2.3 8.7 9.7 1 9.9 0.2 3.4 2 1 1 3 3 3 0 Adhesion protein FadA Flp_N PF03930.14 PRP75686.1 - 0.0018 18.2 0.2 0.0043 17.0 0.2 1.7 1 1 1 2 2 2 1 Recombinase Flp protein N-terminus DUF4286 PF14114.6 PRP75686.1 - 0.015 15.7 0.3 0.022 15.2 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) RasGAP PF00616.19 PRP75687.1 - 7.5e-11 42.1 2.5 2.1e-09 37.4 0.2 3.3 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Retrotrans_gag PF03732.17 PRP75688.1 - 1.5e-06 28.4 0.1 3.2e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Asp_protease_2 PF13650.6 PRP75688.1 - 8.9e-06 26.3 0.0 2.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PRP75688.1 - 7.8e-05 23.2 0.0 0.00016 22.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 PRP75688.1 - 0.0071 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 PRP75688.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF3253 PF11625.8 PRP75688.1 - 0.1 12.9 0.0 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) Trypsin_2 PF13365.6 PRP75691.1 - 4e-08 34.3 0.0 5.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.13 PRP75691.1 - 0.0031 16.8 0.1 0.19 10.9 0.1 2.3 2 0 0 2 2 2 2 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.26 PRP75691.1 - 0.0096 15.7 0.4 0.027 14.3 0.4 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.20 PRP75691.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) DUF1918 PF08940.11 PRP75692.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) VirE PF05272.11 PRP75696.1 - 0.015 15.1 0.1 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Virulence-associated protein E AAA_16 PF13191.6 PRP75696.1 - 0.038 14.4 0.0 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 PRP75696.1 - 0.091 12.8 0.1 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Kelch_1 PF01344.25 PRP75698.1 - 8.8e-39 130.9 16.4 5.2e-09 35.6 0.1 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 PRP75698.1 - 1.1e-31 108.0 9.5 2.7e-06 27.4 0.1 6.3 2 2 4 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PRP75698.1 - 8.2e-24 83.4 9.9 2.4e-05 24.2 0.0 7.6 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP75698.1 - 1.8e-18 65.7 9.3 0.0028 17.6 0.0 6.6 5 1 1 6 6 6 5 Kelch motif BTB_2 PF02214.22 PRP75698.1 - 8.1e-17 61.4 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 PRP75698.1 - 3.3e-14 52.8 2.6 0.006 16.9 0.1 6.3 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP75698.1 - 7.1e-14 51.4 1.4 0.0091 16.0 0.1 5.4 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 PRP75698.1 - 0.0004 20.6 0.0 0.00068 19.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4784 PF16023.5 PRP75698.1 - 0.11 11.5 0.0 0.71 8.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4784) Ank_2 PF12796.7 PRP75700.1 - 1.1e-42 144.5 3.9 8.7e-13 48.7 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75700.1 - 2.5e-31 107.6 0.9 3.5e-08 33.8 0.0 5.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) ELMO_CED12 PF04727.13 PRP75700.1 - 4.1e-31 108.4 0.0 1.3e-30 106.8 0.0 1.8 1 1 0 1 1 1 1 ELMO/CED-12 family Ank PF00023.30 PRP75700.1 - 9.3e-29 98.6 1.2 1e-05 25.8 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 PRP75700.1 - 1.8e-26 89.3 0.0 6.5e-05 23.0 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 PRP75700.1 - 2.4e-25 88.3 0.2 2.9e-08 33.8 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DUF3361 PF11841.8 PRP75700.1 - 1.6e-08 34.6 0.0 4.3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) C2 PF00168.30 PRP75700.1 - 0.0075 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain SH2 PF00017.24 PRP75700.1 - 0.015 15.4 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 SH2 domain DUF4879 PF16219.5 PRP75700.1 - 0.038 14.2 0.0 0.095 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4879) Pkinase_Tyr PF07714.17 PRP75701.1 - 1.5e-61 207.9 0.1 6e-61 206.0 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75701.1 - 1.8e-41 142.3 0.0 4.8e-41 140.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain CUB PF00431.20 PRP75701.1 - 8.5e-06 26.1 0.0 1.8e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 CUB domain EGF_2 PF07974.13 PRP75701.1 - 0.00041 20.7 31.9 0.0075 16.6 5.7 2.8 2 0 0 2 2 2 2 EGF-like domain APH PF01636.23 PRP75701.1 - 0.039 13.9 0.0 0.13 12.2 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP75701.1 - 0.05 12.5 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 PRP75701.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Gelsolin PF00626.22 PRP75702.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Gelsolin repeat RICTOR_N PF14664.6 PRP75703.1 - 2.7e-76 257.0 0.0 8.4e-76 255.4 0.0 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 PRP75703.1 - 5.8e-26 90.3 0.0 3.5e-24 84.6 0.0 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 PRP75703.1 - 1.4e-10 41.5 0.1 3e-08 34.0 0.0 3.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 PRP75703.1 - 0.03 14.5 0.1 5.7 7.3 0.0 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Y_phosphatase2 PF03162.13 PRP75704.1 - 2.4e-22 79.3 0.5 1.4e-21 76.7 0.3 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family TIG PF01833.24 PRP75705.1 - 1.9e-06 27.8 0.0 4.5e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 IPT/TIG domain LAG1-DNAbind PF09271.11 PRP75705.1 - 0.038 14.6 0.0 0.088 13.4 0.0 1.6 1 0 0 1 1 1 0 LAG1, DNA binding IU_nuc_hydro PF01156.19 PRP75706.1 - 1.2e-76 258.2 0.0 2.4e-76 257.2 0.0 1.5 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Na_H_Exchanger PF00999.21 PRP75706.1 - 1.8e-54 185.0 40.1 1.8e-54 185.0 40.1 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family SPRY PF00622.28 PRP75707.1 - 4.3e-12 46.2 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 SPRY domain VIT PF08487.10 PRP75707.1 - 3.7e-09 36.8 1.8 1e-08 35.3 0.7 2.5 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 PRP75707.1 - 4.6e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain ORC6 PF05460.13 PRP75707.1 - 0.013 14.8 25.4 0.039 13.2 25.4 1.8 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WD40 PF00400.32 PRP75708.1 - 4.5e-09 36.8 11.2 0.0043 17.9 0.8 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75708.1 - 0.032 14.5 0.1 2.2 8.7 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 PRP75708.1 - 0.14 10.8 0.0 6.7 5.2 0.0 2.1 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Ank_2 PF12796.7 PRP75709.1 - 2e-10 41.1 0.0 4.7e-05 23.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75709.1 - 1.4e-07 31.9 0.4 0.23 12.1 0.1 4.0 2 2 1 4 4 4 3 Ankyrin repeats (many copies) Amino_oxidase PF01593.24 PRP75709.1 - 1.4e-06 27.9 0.2 3.3e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Ank_5 PF13857.6 PRP75709.1 - 2.9e-06 27.4 0.1 0.021 15.1 0.0 4.3 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP75709.1 - 6.1e-06 26.4 0.3 2.7 8.6 0.1 5.2 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PRP75709.1 - 0.00012 22.2 0.0 60 4.7 0.0 5.6 5 0 0 5 5 5 0 Ankyrin repeat IF-2B PF01008.17 PRP75710.1 - 4.5e-50 170.4 0.1 9.7e-50 169.3 0.1 1.6 1 0 0 1 1 1 1 Initiation factor 2 subunit family RasGEF PF00617.19 PRP75710.1 - 1.7e-46 158.7 3.2 2.9e-46 157.9 0.6 2.7 2 0 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 PRP75710.1 - 1.2e-38 130.7 60.4 1.3e-12 47.3 2.4 7.4 4 1 5 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 PRP75710.1 - 1.3e-22 79.5 46.4 0.00027 21.2 1.4 10.0 7 2 1 11 11 9 6 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 PRP75710.1 - 1.1e-17 64.2 1.1 5.1e-17 62.0 1.1 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif Drf_GBD PF06371.13 PRP75710.1 - 1.6e-09 37.6 0.0 3.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PRP75710.1 - 1.7e-09 37.6 0.9 6e-09 35.8 0.9 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain FERM_f0 PF16511.5 PRP75710.1 - 8.7e-09 35.6 0.3 0.0026 18.0 0.0 3.7 3 0 0 3 3 3 3 N-terminal or F0 domain of Talin-head FERM LRR_1 PF00560.33 PRP75710.1 - 3.6e-05 23.7 26.2 10 7.1 0.2 10.2 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_9 PF14580.6 PRP75710.1 - 0.00016 21.2 14.5 1.2 8.7 0.2 4.5 1 1 3 4 4 4 3 Leucine-rich repeat MATH PF00917.26 PRP75710.1 - 0.034 14.3 0.3 1 9.6 0.2 3.1 3 0 0 3 3 3 0 MATH domain VWA_3 PF13768.6 PRP75711.1 - 1.5e-25 89.9 0.0 2.6e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 PRP75711.1 - 8.7e-20 71.0 0.0 1.9e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain SH2 PF00017.24 PRP75711.1 - 6.5e-14 51.8 0.7 1.4e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 SH2 domain VWA PF00092.28 PRP75711.1 - 2.5e-13 50.6 0.0 5.3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Cbl_N2 PF02761.14 PRP75711.1 - 6.3e-12 46.0 0.1 2.3e-11 44.3 0.1 2.0 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain VIT_2 PF13757.6 PRP75711.1 - 6.5e-08 32.4 0.0 5.6e-06 26.2 0.0 2.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 PRP75711.1 - 8.5e-07 29.6 0.0 2.7e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Cbl_N3 PF02762.14 PRP75711.1 - 0.00026 20.8 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, SH2-like domain TED_complement PF07678.14 PRP75711.1 - 0.1 11.6 0.0 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 A-macroglobulin TED domain Pkinase_Tyr PF07714.17 PRP75712.1 - 8.9e-63 212.0 0.0 1.4e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75712.1 - 1.5e-42 145.8 0.0 2.4e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP75712.1 - 0.0015 18.0 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP75712.1 - 0.0099 15.2 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP75712.1 - 0.027 13.2 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pentapeptide_4 PF13599.6 PRP75713.1 - 0.39 10.9 4.8 16 5.8 0.1 3.9 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) EPTP PF03736.17 PRP75713.1 - 0.47 10.5 3.5 13 5.9 0.1 3.5 3 0 0 3 3 3 0 EPTP domain RGS PF00615.19 PRP75714.1 - 2.9e-32 111.4 0.1 2.9e-32 111.4 0.1 2.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain cNMP_binding PF00027.29 PRP75714.1 - 2.9e-15 56.1 0.0 3.6e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GRAM PF02893.20 PRP75714.1 - 9.8e-05 22.2 0.5 0.00028 20.7 0.5 1.9 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 PRP75714.1 - 0.00046 19.9 1.0 0.0012 18.5 1.0 1.7 1 0 0 1 1 1 1 BAR domain RGS-like PF09128.11 PRP75714.1 - 0.0042 16.8 0.1 0.0042 16.8 0.1 2.2 3 0 0 3 3 3 1 Regulator of G protein signalling-like domain DUF1048 PF06304.11 PRP75714.1 - 0.047 14.1 0.3 0.12 12.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) DUF4960 PF16324.5 PRP75714.1 - 0.58 9.7 3.0 0.72 9.4 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4960) COX6A PF02046.15 PRP75714.1 - 2.4 8.7 6.7 0.61 10.6 0.3 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa HA2 PF04408.23 PRP75715.1 - 0.018 15.3 0.1 0.053 13.8 0.1 1.8 1 1 0 1 1 1 0 Helicase associated domain (HA2) TPP_enzyme_C PF02775.21 PRP75716.1 - 0.082 12.7 0.1 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ALO PF04030.14 PRP75718.1 - 2.3e-11 44.0 0.3 5.9e-11 42.7 0.3 1.7 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 PRP75718.1 - 4.5e-07 29.7 0.0 8.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_5 PF00941.21 PRP75718.1 - 0.069 12.9 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Chol_subst-bind PF09129.11 PRP75718.1 - 0.087 11.8 1.9 0.18 10.7 0.3 2.1 3 0 0 3 3 3 0 Cholesterol oxidase, substrate-binding 14-3-3 PF00244.20 PRP75719.1 - 6.4e-107 356.1 3.4 7.3e-107 355.9 3.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 PRP75719.1 - 0.36 11.4 5.1 0.71 10.4 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 PRP75720.1 - 7.2e-67 225.5 0.0 1.2e-66 224.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75720.1 - 1.6e-47 162.0 0.0 3.3e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP75720.1 - 0.00012 21.0 1.3 0.0002 20.3 1.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP75720.1 - 0.00042 19.7 0.0 0.0011 18.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like FIT1_2 PF17357.2 PRP75720.1 - 0.0064 16.6 0.1 0.0064 16.6 0.1 3.0 3 0 0 3 3 3 1 Facilitor Of iron transport 1 and 2 APH PF01636.23 PRP75720.1 - 0.0065 16.4 0.1 2 8.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP75720.1 - 0.082 12.2 0.3 0.27 10.6 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EGF_2 PF07974.13 PRP75720.1 - 0.084 13.3 6.9 0.16 12.3 6.9 1.5 1 0 0 1 1 1 0 EGF-like domain PBD PF00786.28 PRP75720.1 - 0.088 13.2 0.2 0.22 11.9 0.2 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain RIO1 PF01163.22 PRP75720.1 - 0.14 11.8 0.5 0.29 10.7 0.5 1.5 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 PRP75720.1 - 0.16 11.5 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FIT1_2 PF17357.2 PRP75721.1 - 0.00085 19.4 0.2 0.0014 18.6 0.2 1.3 1 0 0 1 1 1 1 Facilitor Of iron transport 1 and 2 EGF_2 PF07974.13 PRP75721.1 - 0.028 14.8 6.9 0.047 14.1 6.9 1.4 1 0 0 1 1 1 0 EGF-like domain Na_K-ATPase PF00287.18 PRP75721.1 - 0.61 9.2 3.1 1.3 8.1 3.1 1.5 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Glug PF07581.12 PRP75721.1 - 2.3 8.8 4.2 23 5.7 1.1 2.6 2 0 0 2 2 2 0 The GLUG motif SSP160 PF06933.11 PRP75721.1 - 2.9 6.0 6.8 0.74 7.9 0.6 2.0 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Glyco_hydro_cc PF11790.8 PRP75722.1 - 5.6e-51 173.4 2.6 7.1e-51 173.1 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.8 PRP75723.1 - 4.4e-50 170.5 3.9 7.1e-50 169.8 3.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Grg1 PF11034.8 PRP75723.1 - 1.6e-29 101.9 7.5 2.6e-29 101.2 7.5 1.3 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 B9-C2 PF07162.11 PRP75724.1 - 9.8e-42 143.0 0.8 1.5e-41 142.4 0.8 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein CDC45 PF02724.14 PRP75724.1 - 0.94 7.7 58.4 0.0056 15.0 19.8 2.1 2 0 0 2 2 2 0 CDC45-like protein zf-C3Hc3H PF13891.6 PRP75726.1 - 1.1e-05 25.7 4.4 6.8e-05 23.2 4.3 2.4 1 1 0 1 1 1 1 Potential DNA-binding domain DUF2456 PF10445.9 PRP75727.1 - 8e-11 41.9 2.8 8e-11 41.9 2.8 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2456) FtsX PF02687.21 PRP75727.1 - 0.69 10.4 11.5 7 7.2 4.9 2.2 2 0 0 2 2 2 0 FtsX-like permease family Pkinase_Tyr PF07714.17 PRP75728.1 - 2e-75 253.4 0.1 2.7e-75 253.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75728.1 - 8.9e-56 189.2 0.0 1.3e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP75728.1 - 8e-40 134.4 109.2 6.8e-06 25.8 1.0 14.8 7 3 10 17 17 17 14 Leucine rich repeat LRR_4 PF12799.7 PRP75728.1 - 5.4e-30 102.9 123.8 9e-05 22.8 1.8 18.2 9 4 10 20 20 20 14 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP75728.1 - 2.5e-12 45.8 81.3 0.79 9.9 0.8 23.9 25 0 0 25 25 25 5 Leucine Rich repeat LRR_1 PF00560.33 PRP75728.1 - 7.4e-07 28.9 105.8 0.028 14.9 0.2 25.4 26 4 0 26 26 26 4 Leucine Rich Repeat Haspin_kinase PF12330.8 PRP75728.1 - 0.0066 15.4 1.9 0.016 14.2 0.8 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP75728.1 - 0.041 12.7 0.1 0.077 11.8 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PRP75728.1 - 0.046 13.1 0.1 0.092 12.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP75728.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like SKG6 PF08693.10 PRP75728.1 - 0.16 11.4 3.8 0.29 10.6 3.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pertactin PF03212.14 PRP75731.1 - 0.029 14.3 2.6 3.9 7.4 0.4 3.4 3 1 0 4 4 4 0 Pertactin SAGA-Tad1 PF12767.7 PRP75732.1 - 4.2e-14 52.9 3.3 7.5e-12 45.5 1.0 2.1 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit DUF1611 PF07755.11 PRP75732.1 - 0.018 14.3 0.0 0.072 12.4 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain HHH_9 PF17674.1 PRP75732.1 - 0.042 14.8 0.8 0.21 12.5 0.0 2.4 3 0 0 3 3 3 0 HHH domain Yopt PF09467.10 PRP75732.1 - 0.081 13.0 0.1 10 6.3 0.1 2.6 2 0 0 2 2 2 0 Hypothetical protein Yopt YWFCY PF14293.6 PRP75732.1 - 0.12 12.7 0.1 0.55 10.6 0.0 2.1 1 1 1 2 2 2 0 YWFCY protein TAF4 PF05236.14 PRP75732.1 - 0.12 12.1 2.2 0.2 11.4 1.4 1.7 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family MutS_V PF00488.21 PRP75733.1 - 1.3e-63 214.4 1.0 3e-63 213.3 0.3 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 PRP75733.1 - 2.2e-32 112.8 3.9 2.2e-32 112.8 3.9 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 PRP75733.1 - 3.4e-13 50.1 0.2 1e-12 48.5 0.1 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 PRP75733.1 - 5e-10 39.6 1.1 1.1e-08 35.3 0.1 2.8 2 0 0 2 2 2 1 MutS family domain IV AAA_27 PF13514.6 PRP75733.1 - 0.024 14.2 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP75733.1 - 0.053 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 PRP75733.1 - 0.066 13.1 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pkinase_Tyr PF07714.17 PRP75734.1 - 1.8e-51 175.0 0.0 2.7e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP75734.1 - 5.7e-48 163.6 0.0 9.4e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP75734.1 - 2e-12 47.0 0.0 4.4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 SH2 domain DUF4395 PF14340.6 PRP75734.1 - 2.3e-11 44.1 8.2 2.3e-11 44.1 8.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4395) APH PF01636.23 PRP75734.1 - 0.00015 21.8 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP75734.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP75734.1 - 0.0028 16.7 0.0 0.074 12.0 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP75734.1 - 0.0038 16.0 0.0 0.019 13.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Cbl_N2 PF02761.14 PRP75734.1 - 0.0061 17.3 0.1 0.015 16.0 0.1 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Seadorna_VP7 PF07387.11 PRP75734.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 UPF0052 PF01933.18 PRP75735.1 - 3.1e-54 184.2 0.0 4.3e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Herpes_US9 PF06072.11 PRP75735.1 - 0.024 14.5 0.4 0.062 13.2 0.4 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 RasGEF PF00617.19 PRP75736.1 - 4.3e-37 128.0 1.7 7e-37 127.3 0.3 2.1 2 0 0 2 2 2 1 RasGEF domain CTK3 PF12243.8 PRP75736.1 - 3.3e-13 49.7 3.6 1.3e-12 47.8 2.2 2.4 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 PRP75736.1 - 1.7e-08 35.2 0.8 6.9e-08 33.2 0.4 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. HEPN-like_int PF18867.1 PRP75736.1 - 0.052 13.4 0.1 0.35 10.7 0.1 2.3 2 0 0 2 2 2 0 HEPN-like integron domain Pkinase PF00069.25 PRP75737.1 - 1.7e-29 103.0 0.1 3e-26 92.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75737.1 - 3e-28 98.8 0.3 7.8e-22 77.8 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP75737.1 - 0.00078 18.3 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase zinc_ribbon_2 PF13240.6 PRP75739.1 - 0.00075 19.1 3.4 0.0015 18.2 3.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 PRP75739.1 - 0.0043 17.0 5.0 0.013 15.5 5.0 1.8 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 PRP75739.1 - 0.097 13.4 1.8 0.29 11.9 1.8 1.8 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 PRP75739.1 - 0.21 11.0 4.3 0.67 9.4 4.0 2.0 1 1 1 2 2 2 0 zinc-ribbon domain IBR PF01485.21 PRP75740.1 - 1.5e-09 37.9 33.0 1.5e-08 34.7 7.7 3.8 3 1 0 3 3 3 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PRP75740.1 - 6.6e-06 26.4 4.8 6.6e-06 26.4 4.8 4.1 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 PRP75740.1 - 7.1e-06 25.9 3.5 7.1e-06 25.9 3.5 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP75740.1 - 6.2e-05 22.8 4.5 6.2e-05 22.8 4.5 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP75740.1 - 0.00024 20.9 4.2 0.00024 20.9 4.2 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP75740.1 - 0.0081 16.1 4.1 0.0081 16.1 4.1 3.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PRP75740.1 - 0.022 14.9 3.3 0.022 14.9 3.3 4.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PRP75740.1 - 0.033 14.1 2.4 0.033 14.1 2.4 4.0 3 1 0 3 3 3 0 zf-RING of BARD1-type protein TRAF6_Z2 PF18048.1 PRP75740.1 - 0.14 12.3 10.2 0.35 11.0 3.4 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 DEP PF00610.21 PRP75741.1 - 0.00032 20.7 0.0 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF547 PF04784.14 PRP75741.1 - 0.0016 18.5 0.0 0.005 16.9 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF547 S1-P1_nuclease PF02265.16 PRP75742.1 - 8.6e-59 199.4 0.1 1e-58 199.2 0.1 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease zf-HC5HC2H_2 PF13832.6 PRP75743.1 - 3e-24 85.3 10.6 3e-24 85.3 10.6 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PRP75743.1 - 1.2e-17 63.9 9.9 1.2e-17 63.9 9.9 3.7 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 PRP75743.1 - 1.1e-12 47.2 5.9 1.1e-12 47.2 5.9 3.1 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.9 PRP75743.1 - 8.1e-12 45.8 0.5 8.1e-12 45.8 0.5 4.1 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD PF00628.29 PRP75743.1 - 3e-07 30.2 11.9 3e-07 30.2 11.9 3.6 3 2 0 3 3 3 2 PHD-finger ubiquitin PF00240.23 PRP75744.1 - 2.3e-16 59.3 0.1 6.3e-16 57.9 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PRP75744.1 - 3.8e-08 33.0 0.0 7.1e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP75744.1 - 0.0002 21.7 0.4 0.0018 18.7 0.1 2.4 1 1 1 2 2 2 1 Ubiquitin-like domain VCH_CASS14 PF18315.1 PRP75744.1 - 0.024 14.7 0.1 0.59 10.2 0.0 2.3 2 1 0 2 2 2 0 Integron cassette protein VCH_CASS1 chain MPLKIP PF15502.6 PRP75745.1 - 0.0031 17.7 0.5 0.0054 16.9 0.5 1.5 1 0 0 1 1 1 1 M-phase-specific PLK1-interacting protein Aa_trans PF01490.18 PRP75746.1 - 1.1e-06 27.7 34.2 1.1e-06 27.6 30.6 2.6 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein PH PF00169.29 PRP75747.1 - 3.6e-08 33.8 1.5 6.8e-08 33.0 1.5 1.4 1 0 0 1 1 1 1 PH domain VWA_2 PF13519.6 PRP75748.1 - 0.0012 19.5 0.0 0.0019 18.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2040 PF09745.9 PRP75749.1 - 2.8e-31 108.1 20.2 2.8e-31 108.1 20.2 4.7 2 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) RhoGAP PF00620.27 PRP75750.1 - 2.5e-09 37.1 0.7 6.7e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain DDRGK PF09756.9 PRP75750.1 - 0.029 14.0 25.2 0.072 12.7 25.2 1.6 1 0 0 1 1 1 0 DDRGK domain ARGLU PF15346.6 PRP75750.1 - 0.1 12.5 33.2 0.074 12.9 31.4 1.6 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 AAA_11 PF13086.6 PRP75750.1 - 0.59 9.9 9.6 1.1 9.0 9.6 1.4 1 0 0 1 1 1 0 AAA domain Asp-B-Hydro_N PF05279.11 PRP75750.1 - 0.77 9.8 14.3 0.63 10.1 12.1 1.9 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.19 PRP75750.1 - 3.2 5.6 10.1 4.8 5.0 10.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VIR_N PF15912.5 PRP75750.1 - 8.5 5.9 10.7 20 4.7 10.7 1.5 1 0 0 1 1 1 0 Virilizer, N-terminal CAP59_mtransfer PF11735.8 PRP75751.1 - 8.4e-57 192.6 0.0 2.3e-56 191.2 0.0 1.7 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ras PF00071.22 PRP75751.1 - 1.8e-12 47.2 0.0 3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP75751.1 - 0.064 13.5 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 PRP75751.1 - 0.22 10.6 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Pkinase_Tyr PF07714.17 PRP75753.1 - 1.1e-67 228.1 0.0 1.5e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP75753.1 - 1.4e-48 162.5 88.7 5.1e-07 29.4 1.1 13.7 10 6 6 16 16 16 12 Leucine rich repeat Pkinase PF00069.25 PRP75753.1 - 9.2e-47 159.6 0.0 1.3e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP75753.1 - 3.3e-38 129.1 89.9 8.3e-05 22.9 0.0 16.2 13 4 3 17 17 17 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP75753.1 - 1.5e-14 52.3 80.4 0.77 10.5 0.1 24.9 24 4 0 24 24 24 5 Leucine Rich Repeat LRR_6 PF13516.6 PRP75753.1 - 2.5e-07 30.2 83.4 0.047 13.7 0.5 21.4 26 0 0 26 26 26 5 Leucine Rich repeat Kdo PF06293.14 PRP75753.1 - 0.044 13.1 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Amnionless PF14828.6 PRP75753.1 - 0.21 10.3 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF1819 PF08849.11 PRP75755.1 - 0.012 15.4 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) MAD PF05557.13 PRP75756.1 - 0.055 11.8 0.1 0.055 11.8 0.1 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein PIN_3 PF13470.6 PRP75756.1 - 0.071 13.9 0.2 0.17 12.7 0.1 1.6 2 0 0 2 2 2 0 PIN domain AIP3 PF03915.13 PRP75756.1 - 0.086 11.9 0.9 0.14 11.3 0.9 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 DUF4140 PF13600.6 PRP75756.1 - 0.094 13.2 6.4 1 9.8 0.0 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.6 PRP75756.1 - 0.11 12.7 5.4 0.34 11.1 4.6 1.9 2 0 0 2 2 2 0 Up-regulated During Septation DUF2730 PF10805.8 PRP75756.1 - 0.16 12.1 0.9 3.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ATG16 PF08614.11 PRP75756.1 - 1.3 9.3 13.2 0.074 13.3 7.4 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TMEM70 PF06979.12 PRP75757.1 - 0.0027 18.1 0.2 0.0044 17.4 0.2 1.4 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex BPD_transp_2 PF02653.16 PRP75757.1 - 0.0062 15.7 0.4 0.0096 15.1 0.4 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Ninjurin PF04923.12 PRP75757.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Ninjurin TMEM223 PF14640.6 PRP75757.1 - 0.063 13.4 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 Colicin_M PF14859.6 PRP75757.1 - 0.09 11.9 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Colicin M Spherulin4 PF12138.8 PRP75758.1 - 2.6e-51 174.6 3.6 3.4e-51 174.2 3.6 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 Ank_2 PF12796.7 PRP75758.1 - 7.8e-06 26.4 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75758.1 - 0.0012 19.4 0.0 0.0041 17.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP75758.1 - 0.088 13.3 0.1 1.4 9.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Prd1-P2 PF09214.11 PRP75760.1 - 0.1 11.3 0.0 0.1 11.3 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 ApoO PF09769.9 PRP75761.1 - 4.2 7.3 25.3 1.1 9.2 0.9 5.6 4 1 2 6 6 6 0 Apolipoprotein O DUF2569 PF10754.9 PRP75763.1 - 0.03 14.8 6.7 0.26 11.7 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF2663 PF10864.8 PRP75763.1 - 0.12 12.8 4.3 0.28 11.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) TMEM208_SND2 PF05620.11 PRP75763.1 - 7.9 6.2 6.2 6.8 6.5 0.1 2.3 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Saf_2TM PF18303.1 PRP75763.1 - 8.7 5.9 14.5 0.052 13.1 3.4 2.5 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Fructosamin_kin PF03881.14 PRP75764.1 - 6.9e-45 153.5 0.0 1e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase GFRP PF06399.13 PRP75764.1 - 0.16 11.8 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Ank_2 PF12796.7 PRP75765.1 - 2.7e-14 53.5 0.0 3.7e-07 30.7 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP75765.1 - 2.6e-06 27.6 0.1 0.048 14.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP75765.1 - 2e-05 25.1 0.0 3.5 8.3 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75765.1 - 0.078 13.6 0.1 13 6.8 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 PRP75765.1 - 0.13 12.8 0.1 19 5.9 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat LTP_2 PF14368.6 PRP75766.1 - 0.071 13.2 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Probable lipid transfer RhoGEF PF00621.20 PRP75767.1 - 1.2e-36 126.6 0.9 2.4e-36 125.7 0.9 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PRP75767.1 - 2.8e-05 24.6 0.0 7.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 PH domain PPP4R2 PF09184.11 PRP75767.1 - 0.059 13.0 24.1 0.094 12.3 23.1 1.8 2 0 0 2 2 2 0 PPP4R2 PH_4 PF15404.6 PRP75767.1 - 0.098 12.4 0.0 0.098 12.4 0.0 3.6 3 1 0 3 3 2 0 Pleckstrin homology domain RR_TM4-6 PF06459.12 PRP75767.1 - 0.24 11.2 25.4 0.44 10.3 25.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SID-1_RNA_chan PF13965.6 PRP75767.1 - 0.44 8.9 1.8 0.68 8.3 1.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4050 PF13259.6 PRP75767.1 - 0.74 10.1 14.3 1.7 8.9 14.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Merozoite_SPAM PF07133.11 PRP75767.1 - 2 8.4 40.0 4.5 7.2 40.0 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) FGF-BP1 PF06473.12 PRP75767.1 - 4 7.2 16.8 7.8 6.3 16.8 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) CDC45 PF02724.14 PRP75767.1 - 4.7 5.4 25.7 8.4 4.5 25.7 1.5 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.6 PRP75767.1 - 5.8 6.8 25.6 14 5.5 25.6 1.6 1 0 0 1 1 1 0 Spore coat protein CotO SLC12 PF03522.15 PRP75767.1 - 6.8 5.6 18.7 12 4.7 18.7 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 PRP75767.1 - 9.9 4.8 23.1 17 4.1 23.1 1.4 1 0 0 1 1 1 0 Presenilin MIF4G_like PF09088.11 PRP75768.1 - 6.9e-32 110.8 3.9 4.8e-29 101.5 1.2 2.5 1 1 1 2 2 2 2 MIF4G like MIF4G_like_2 PF09090.11 PRP75768.1 - 3.8e-31 108.5 0.1 8.3e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 MIF4G like ABC2_membrane PF01061.24 PRP75770.1 - 1.2e-31 109.8 20.4 1.2e-31 109.8 20.4 2.2 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 PRP75770.1 - 1.4e-23 83.9 0.0 2.4e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PRP75770.1 - 0.00091 19.1 0.5 0.65 9.8 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PRP75770.1 - 0.0033 16.9 0.3 0.046 13.2 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 PRP75770.1 - 0.0044 16.2 18.6 0.0044 16.2 18.6 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein EGF_2 PF07974.13 PRP75770.1 - 0.021 15.2 0.3 0.021 15.2 0.3 2.5 2 0 0 2 2 2 0 EGF-like domain RsgA_GTPase PF03193.16 PRP75770.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 PRP75770.1 - 0.15 12.3 0.0 0.73 10.1 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 PRP75770.1 - 0.19 12.3 0.1 0.41 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP75770.1 - 0.19 11.5 0.3 0.42 10.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HNH_2 PF13391.6 PRP75771.1 - 0.0063 16.6 0.1 0.023 14.8 0.1 2.0 1 0 0 1 1 1 1 HNH endonuclease Streptin-Immun PF11083.8 PRP75771.1 - 2.4 8.6 4.0 2.9 8.4 0.3 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein NAS PF03059.16 PRP75772.1 - 0.075 12.4 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein RNase_H PF00075.24 PRP75773.1 - 5.1e-06 26.7 0.1 0.00056 20.1 0.1 2.5 1 1 0 1 1 1 1 RNase H Latrotoxin_C PF15658.6 PRP75773.1 - 0.00026 20.8 0.2 0.33 10.7 0.0 2.4 2 0 0 2 2 2 2 Latrotoxin C-terminal domain BTAD PF03704.17 PRP75773.1 - 0.0097 16.3 0.0 0.94 9.9 0.0 2.3 1 1 1 2 2 2 1 Bacterial transcriptional activator domain FtsZ_C PF12327.8 PRP75773.1 - 0.051 13.9 0.1 23 5.4 0.0 2.8 3 0 0 3 3 3 0 FtsZ family, C-terminal domain PI3_PI4_kinase PF00454.27 PRP75782.1 - 1.6e-31 110.0 0.0 2.7e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ABC_tran PF00005.27 PRP75783.1 - 9.7e-57 191.3 0.5 2.9e-27 95.9 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.7 PRP75783.1 - 3.2e-30 105.4 40.1 1.9e-23 83.1 14.1 3.1 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 PRP75783.1 - 4.6e-21 75.9 5.8 1.5e-09 38.1 0.0 4.5 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PRP75783.1 - 2.8e-07 30.6 5.5 0.59 9.8 0.0 5.2 4 1 0 5 5 5 3 AAA ATPase domain SMC_N PF02463.19 PRP75783.1 - 1.3e-06 28.0 0.0 0.21 11.0 0.0 3.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 PRP75783.1 - 9.9e-05 22.1 0.4 2.9 7.6 0.0 4.0 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_23 PF13476.6 PRP75783.1 - 0.00081 19.9 10.3 0.02 15.4 0.2 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 PRP75783.1 - 0.0028 17.3 2.1 0.4 10.5 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 PRP75783.1 - 0.0032 17.7 0.0 4.7 7.5 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 PRP75783.1 - 0.0063 16.4 0.3 0.15 11.9 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 PRP75783.1 - 0.0086 15.7 2.0 0.62 9.7 0.2 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ABC2_membrane_2 PF12679.7 PRP75783.1 - 0.025 13.9 26.1 0.042 13.1 11.6 2.9 3 0 0 3 3 3 0 ABC-2 family transporter protein AAA_30 PF13604.6 PRP75783.1 - 0.042 13.6 0.9 4.8 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PRP75783.1 - 0.068 12.5 0.1 12 5.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 PRP75783.1 - 0.094 13.1 0.1 11 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 PRP75783.1 - 0.15 11.8 1.7 4.9 6.8 0.1 2.8 2 0 0 2 2 2 0 AAA domain Peptidase_U32_C PF16325.5 PRP75783.1 - 0.18 12.1 1.3 0.77 10.1 0.1 2.5 3 0 0 3 3 2 0 Peptidase family U32 C-terminal domain AAA_22 PF13401.6 PRP75783.1 - 0.18 12.1 2.6 2.5 8.4 0.1 3.1 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PRP75783.1 - 0.4 10.0 2.1 22 4.3 0.0 3.4 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AIM24 PF01987.17 PRP75784.1 - 2e-41 142.0 1.3 2.5e-41 141.7 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PI-PLC-X PF00388.19 PRP75785.1 - 0.0043 16.6 0.2 0.007 16.0 0.2 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Calreticulin PF00262.18 PRP75786.1 - 2.7e-83 279.9 12.4 6.1e-62 209.6 4.4 2.1 1 1 1 2 2 2 2 Calreticulin family CT47 PF15623.6 PRP75786.1 - 0.0016 18.4 7.1 0.075 12.9 4.6 2.3 2 0 0 2 2 2 2 Cancer/testis gene family 47 Fungal_TACC PF12709.7 PRP75786.1 - 0.055 13.9 0.9 0.46 11.0 0.0 2.7 2 1 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins AdoHcyase PF05221.17 PRP75787.1 - 3.1e-145 482.9 0.0 3.6e-145 482.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 PRP75787.1 - 6.1e-84 280.0 1.5 9.3e-84 279.4 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PRP75787.1 - 6.1e-07 29.0 0.2 1.2e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PRP75787.1 - 4.9e-05 23.0 0.2 9.1e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 PRP75787.1 - 0.00029 21.2 0.2 0.00069 20.0 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 PRP75787.1 - 0.0011 19.3 0.4 0.0044 17.3 0.4 2.1 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 PRP75787.1 - 0.033 14.3 0.1 0.077 13.1 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Act-Frag_cataly PF09192.10 PRP75788.1 - 1.2e-33 116.8 0.0 2.9e-33 115.5 0.0 1.6 1 1 0 1 1 1 1 Actin-fragmin kinase, catalytic CENP-C_C PF11699.8 PRP75789.1 - 3.9e-05 23.8 0.0 0.00012 22.2 0.0 1.9 1 0 0 1 1 1 1 Mif2/CENP-C like Ribosomal_L31e PF01198.19 PRP75790.1 - 1.7e-32 111.5 2.0 2.3e-32 111.1 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e 2OG-FeII_Oxy_3 PF13640.6 PRP75791.1 - 5.1e-17 62.6 0.0 9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PRP75791.1 - 4.8e-09 36.8 0.0 1.2e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Adap_comp_sub PF00928.21 PRP75792.1 - 1.5e-43 149.1 1.4 2.2e-43 148.6 1.4 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PRP75792.1 - 0.0055 16.6 0.6 0.012 15.6 0.4 1.8 2 1 0 2 2 2 1 Clathrin adaptor complex small chain muHD PF10291.9 PRP75792.1 - 0.043 13.2 0.2 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain SANT_DAMP1_like PF16282.5 PRP75793.1 - 5.5e-27 93.8 6.3 1.1e-26 92.8 6.3 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 PRP75793.1 - 9.1e-11 41.9 12.5 1.2e-09 38.3 8.5 3.1 2 1 0 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 PRP75793.1 - 0.032 14.5 1.1 0.23 11.7 0.2 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PRP75793.1 - 0.077 13.2 1.5 0.16 12.2 0.2 2.2 2 1 1 3 3 3 0 Myb-like DNA-binding domain TFIID_30kDa PF03540.13 PRP75794.1 - 9.3e-22 76.7 0.1 1.3e-21 76.3 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit SLX9 PF15341.6 PRP75794.1 - 0.0022 18.4 0.4 0.0043 17.4 0.3 1.5 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 ERCC3_RAD25_C PF16203.5 PRP75794.1 - 0.012 14.8 0.2 0.015 14.5 0.2 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TAF4 PF05236.14 PRP75794.1 - 0.04 13.7 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Methyltransf_4 PF02390.17 PRP75797.1 - 7.3e-52 175.3 0.0 1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 PRP75797.1 - 8.9e-05 23.1 0.0 0.00018 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP75797.1 - 0.00052 19.6 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 PRP75797.1 - 0.0022 18.7 0.1 0.018 15.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP75797.1 - 0.011 16.4 0.0 0.084 13.5 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Ribos_L4_asso_C PF14374.6 PRP75797.1 - 0.016 15.2 1.8 0.2 11.7 0.4 2.4 2 0 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain Methyltransf_31 PF13847.6 PRP75797.1 - 0.019 14.8 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 PRP75797.1 - 0.099 12.2 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 BBIP10 PF14777.6 PRP75798.1 - 1.4e-17 62.9 3.0 1.6e-17 62.8 3.0 1.0 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 NICE-3 PF07406.11 PRP75799.1 - 0.00061 19.8 0.1 0.00099 19.1 0.1 1.3 1 0 0 1 1 1 1 NICE-3 protein FERM_f0 PF16511.5 PRP75800.1 - 1.3e-05 25.4 0.0 1.6e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Kindlin_2_N PF18124.1 PRP75800.1 - 0.073 13.3 0.0 0.096 12.9 0.0 1.1 1 0 0 1 1 1 0 Kindlin-2 N-terminal domain TMEM107 PF14995.6 PRP75802.1 - 3e-21 76.1 5.1 3.5e-21 75.9 5.1 1.0 1 0 0 1 1 1 1 Transmembrane protein AMP-binding PF00501.28 PRP75804.1 - 1.1e-100 337.2 0.1 1.6e-100 336.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP75804.1 - 0.002 19.1 0.0 0.0048 17.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3592 PF12158.8 PRP75804.1 - 0.11 12.6 0.1 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) DDE_2 PF02914.15 PRP75806.1 - 0.06 13.1 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase DUF4139 PF13598.6 PRP75807.1 - 1.1e-51 175.5 1.3 1.7e-51 174.9 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 PRP75807.1 - 3e-05 24.4 11.0 6.7e-05 23.3 0.1 4.0 3 1 1 4 4 4 1 N-terminal domain of unknown function (DUF4140) DUF5452 PF17533.2 PRP75807.1 - 0.032 14.3 2.0 0.074 13.1 2.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5452) DGF-1_C PF11040.8 PRP75807.1 - 0.41 10.7 3.3 1.3 9.0 0.2 2.7 2 1 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2031 PF09592.10 PRP75807.1 - 1 8.8 8.4 0.41 10.1 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) Lipase_GDSL_2 PF13472.6 PRP75809.1 - 5.1e-10 40.0 0.0 8.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-RING_5 PF14634.6 PRP75810.1 - 5.7 7.0 17.0 21 5.2 17.2 2.0 1 1 0 1 1 1 0 zinc-RING finger domain WD40 PF00400.32 PRP75811.1 - 5e-40 134.7 35.7 8.4e-08 32.8 1.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75811.1 - 5.2e-17 61.9 5.9 6.6e-05 23.1 0.3 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP75811.1 - 3.2e-07 30.4 5.5 0.012 15.5 0.6 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PRP75811.1 - 0.0027 17.1 0.0 0.46 9.8 0.0 2.8 1 1 3 4 4 4 3 WD40-like domain VID27 PF08553.10 PRP75811.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Ras PF00071.22 PRP75814.1 - 2.6e-43 147.4 0.0 6.1e-43 146.2 0.0 1.6 2 0 0 2 2 2 1 Ras family WD40 PF00400.32 PRP75814.1 - 1.7e-32 110.9 15.4 9e-08 32.7 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.11 PRP75814.1 - 2e-32 111.0 1.1 3.8e-32 110.1 1.1 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like Roc PF08477.13 PRP75814.1 - 3.2e-15 56.4 0.0 4.9e-14 52.6 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ANAPC4_WD40 PF12894.7 PRP75814.1 - 8.7e-14 51.6 0.1 9.6e-05 22.6 0.0 4.9 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 PRP75814.1 - 2.3e-06 27.3 0.1 5.2e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit eIF2A PF08662.11 PRP75814.1 - 1.3e-05 25.2 0.1 0.18 11.7 0.0 2.9 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 PRP75814.1 - 0.00012 22.2 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 U-box domain Arf PF00025.21 PRP75814.1 - 0.00057 19.4 0.0 0.002 17.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF87 PF01935.17 PRP75814.1 - 0.027 14.6 1.4 0.3 11.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain GTP_EFTU PF00009.27 PRP75814.1 - 0.028 14.0 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Rtf2 PF04641.12 PRP75814.1 - 0.034 13.5 1.2 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger RsgA_GTPase PF03193.16 PRP75814.1 - 0.053 13.4 0.1 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Cep57_CLD_2 PF14197.6 PRP75814.1 - 0.49 10.5 3.4 1.5 9.0 3.4 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Ras PF00071.22 PRP75815.1 - 1.4e-51 174.3 0.1 1.7e-51 174.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP75815.1 - 2.7e-15 56.6 0.0 6.5e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP75815.1 - 3.8e-06 26.5 0.0 4.3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP75815.1 - 7.2e-05 22.7 0.0 0.065 13.1 0.0 2.4 2 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP75815.1 - 0.03 14.4 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP75815.1 - 0.05 13.1 0.0 0.16 11.5 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Glyco_hydro_88 PF07470.13 PRP75816.1 - 3.3e-15 56.0 2.5 4.5e-15 55.6 2.5 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 CS PF04969.16 PRP75818.1 - 5.8e-16 59.3 0.1 1.5e-15 57.9 0.1 1.8 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 PRP75818.1 - 2.9e-10 40.0 0.2 9.2e-10 38.4 0.2 1.9 1 1 0 1 1 1 1 N-terminal conserved domain of Nudc. DIM1 PF02966.16 PRP75819.1 - 2e-63 212.1 0.5 2.3e-63 211.9 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 PRP75819.1 - 2.7e-05 24.1 0.0 3.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 PRP75819.1 - 0.0066 16.8 0.8 0.015 15.6 0.8 1.7 1 1 1 2 2 2 1 Thioredoxin-like DUF3192 PF11399.8 PRP75819.1 - 0.016 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Thioredoxin_9 PF14595.6 PRP75819.1 - 0.069 12.9 0.3 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin TRAP_alpha PF03896.16 PRP75820.1 - 6.8 5.8 10.0 3.2 6.9 6.6 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2347 PF09804.9 PRP75820.1 - 9.3 5.7 9.8 0.45 10.1 4.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Tyr-DNA_phospho PF06087.12 PRP75821.1 - 3.4e-75 253.6 0.0 4.9e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase RasGAP PF00616.19 PRP75822.1 - 8.6e-26 90.9 0.0 1.4e-23 83.7 0.0 3.0 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RhoGAP PF00620.27 PRP75822.1 - 5.1e-24 84.8 0.2 1.6e-23 83.2 0.2 1.9 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.32 PRP75822.1 - 0.0041 17.9 3.7 2.6 9.1 0.2 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.25 PRP75823.1 - 3.9e-61 206.7 0.0 1.4e-60 204.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75823.1 - 1.7e-32 112.8 0.0 6.9e-27 94.4 0.1 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP75823.1 - 2.8e-05 23.6 1.7 0.017 14.5 0.0 3.7 4 0 0 4 4 4 1 Kinase-like Pkinase_fungal PF17667.1 PRP75823.1 - 0.0007 18.5 0.1 0.0014 17.5 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pox_polyA_pol_N PF12630.7 PRP75823.1 - 0.013 15.8 0.4 0.046 14.1 0.3 1.9 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain KIP1 PF07765.12 PRP75823.1 - 0.088 12.9 0.5 0.39 10.9 0.5 2.1 1 0 0 1 1 1 0 KIP1-like protein APH PF01636.23 PRP75823.1 - 0.098 12.6 0.3 1.2 9.0 0.4 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family 3-alpha PF03475.14 PRP75823.1 - 0.14 12.1 0.2 0.34 10.8 0.2 1.7 1 0 0 1 1 1 0 3-alpha domain LNS2 PF08235.13 PRP75824.1 - 0.2 11.1 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) PHD PF00628.29 PRP75826.1 - 0.011 15.7 4.6 0.028 14.3 4.6 1.6 1 1 0 1 1 1 0 PHD-finger Acetyltransf_1 PF00583.25 PRP75827.1 - 3.3e-14 53.1 0.0 4.2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP75827.1 - 8.9e-12 45.0 0.0 1.4e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP75827.1 - 4.6e-10 39.8 0.2 7.1e-10 39.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP75827.1 - 3.9e-05 23.8 0.0 5.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP75827.1 - 0.00037 20.6 0.0 0.07 13.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP75827.1 - 0.00044 20.9 0.0 0.00059 20.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP75827.1 - 0.0013 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 PRP75827.1 - 0.0028 17.5 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP75827.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 PRP75827.1 - 0.014 15.1 0.0 0.067 12.9 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_hydro PF18290.1 PRP75827.1 - 0.087 12.8 0.1 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Nudix hydrolase domain Patatin PF01734.22 PRP75828.1 - 9.9e-09 35.7 5.9 9.9e-09 35.7 5.9 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase FAD_binding_1 PF00667.20 PRP75829.1 - 5.2e-19 68.7 0.0 1.4e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 PRP75829.1 - 1.5e-11 44.9 0.1 7.5e-11 42.6 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.9 PRP75829.1 - 8.2e-11 41.4 7.6 1e-10 41.1 4.2 2.4 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal SET PF00856.28 PRP75829.1 - 0.029 14.8 0.0 0.069 13.5 0.0 1.8 1 0 0 1 1 1 0 SET domain DUF3783 PF12646.7 PRP75830.1 - 0.2 11.6 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Ins_beta PF03488.14 PRP75831.1 - 0.059 13.4 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type zf-C2H2_jaz PF12171.8 PRP75832.1 - 0.055 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP75832.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PRP75832.1 - 0.11 12.8 0.7 0.25 11.7 0.7 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF755 PF05501.11 PRP75832.1 - 6 7.2 14.1 3.3 8.0 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) WD40 PF00400.32 PRP75833.1 - 5.3e-13 49.2 9.8 2.1e-05 25.2 0.5 7.4 7 1 0 7 7 7 1 WD domain, G-beta repeat TPR_1 PF00515.28 PRP75833.1 - 2e-10 40.0 10.9 0.00014 21.5 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP75833.1 - 2.1e-09 36.8 10.7 0.00073 19.5 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP75833.1 - 3e-08 33.2 3.2 0.0037 17.4 0.1 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP75833.1 - 1.7e-06 27.6 1.9 0.009 15.7 0.2 3.4 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 PRP75833.1 - 2e-06 28.0 8.5 1.9e-05 24.9 1.4 3.5 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP75833.1 - 3.8e-06 26.9 3.5 5e-06 26.6 0.9 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP75833.1 - 0.00019 21.2 3.7 0.016 15.2 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP75833.1 - 0.00027 21.4 3.1 1.1 10.1 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP75833.1 - 0.00032 20.9 4.8 0.0022 18.2 1.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP75833.1 - 0.00058 20.3 3.5 0.0033 17.9 1.6 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP75833.1 - 0.21 12.2 5.6 15 6.4 0.2 3.3 3 1 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP75833.1 - 0.66 10.9 4.6 4.8 8.3 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF615 PF04751.14 PRP75833.1 - 0.87 9.6 9.2 12 5.9 9.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF615) ADP_ribosyl_GH PF03747.14 PRP75833.1 - 3.6 7.2 5.1 20 4.8 1.9 2.8 2 1 1 3 3 3 0 ADP-ribosylglycohydrolase TPR_10 PF13374.6 PRP75833.1 - 9.3 6.3 6.7 25 4.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 PRP75834.1 - 1.1e-14 54.5 10.0 0.0001 23.0 0.1 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75834.1 - 2.5e-10 40.5 0.7 0.043 14.1 0.0 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP75834.1 - 1e-05 24.7 0.4 0.025 13.6 0.1 2.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP75834.1 - 0.0012 18.7 0.8 11 5.8 0.0 3.7 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Herpes_DNAp_acc PF04929.12 PRP75834.1 - 0.39 9.7 0.0 0.39 9.7 0.0 2.2 3 0 0 3 3 3 0 Herpes DNA replication accessory factor Met_10 PF02475.16 PRP75835.1 - 2.5e-67 226.5 0.2 4.1e-67 225.8 0.2 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 PRP75835.1 - 0.0041 16.8 0.0 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.10 PRP75835.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase EpmC PF04315.12 PRP75835.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Elongation factor P hydroxylase TRM PF02005.16 PRP75835.1 - 0.044 13.0 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_4 PF02390.17 PRP75835.1 - 0.064 12.7 0.1 0.24 10.8 0.0 2.0 2 1 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 PRP75835.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF945 PF06097.11 PRP75835.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) CEL_III_C PF18054.1 PRP75836.1 - 0.084 12.9 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 CEL-III C-terminal TPR_1 PF00515.28 PRP75839.1 - 7.9e-05 22.3 5.5 0.29 11.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP75839.1 - 0.00036 20.2 0.2 0.00096 18.8 0.2 1.8 1 0 0 1 1 1 1 TPR repeat NYD-SP12_N PF15015.6 PRP75839.1 - 0.0023 16.4 0.1 0.0036 15.7 0.1 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal TPR_2 PF07719.17 PRP75839.1 - 0.0025 17.8 7.0 0.099 12.8 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP75839.1 - 0.0037 17.4 2.4 0.051 13.8 2.4 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PRP75839.1 - 0.0039 17.8 3.0 0.56 10.9 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_25 PF13649.6 PRP75839.1 - 0.0085 16.8 0.0 0.11 13.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain TPR_14 PF13428.6 PRP75839.1 - 0.021 15.6 1.1 4.2 8.5 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP75839.1 - 0.071 13.4 2.4 0.3 11.4 0.2 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP75839.1 - 0.085 13.4 4.2 0.51 10.9 0.5 3.3 2 1 2 4 4 4 0 Tetratricopeptide repeat Z1 PF10593.9 PRP75839.1 - 0.087 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Z1 domain ADP_ribosyl_GH PF03747.14 PRP75839.1 - 0.16 11.6 0.3 0.35 10.6 0.1 1.6 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase zinc_ribbon_11 PF11682.8 PRP75841.1 - 0.062 13.3 0.0 0.066 13.2 0.0 1.1 1 0 0 1 1 1 0 Probable zinc-ribbon EVC2_like PF12297.8 PRP75842.1 - 0.041 12.6 0.1 0.073 11.7 0.1 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Ribosomal_L13 PF00572.18 PRP75843.1 - 1.4e-39 135.2 0.4 2.7e-39 134.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 RPN6_N PF18055.1 PRP75844.1 - 3.8e-27 94.9 0.6 3.8e-27 94.9 0.6 2.8 2 2 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 PRP75844.1 - 8e-13 48.8 0.7 8e-13 48.8 0.7 2.6 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 PRP75844.1 - 1.1e-12 47.4 0.4 2e-12 46.6 0.4 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 PRP75844.1 - 0.023 14.1 5.2 0.054 12.9 5.2 1.6 1 0 0 1 1 1 0 MalT-like TPR region TPR_7 PF13176.6 PRP75844.1 - 0.029 14.4 0.9 12 6.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Laminin_II PF06009.12 PRP75844.1 - 0.45 10.5 4.5 1.6 8.8 0.6 3.0 3 0 0 3 3 3 0 Laminin Domain II MgsA_C PF12002.8 PRP75845.1 - 5e-51 172.9 0.0 8.3e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.29 PRP75845.1 - 9.9e-15 55.1 0.0 1.6e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PRP75845.1 - 5.3e-10 39.3 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 PRP75845.1 - 4.2e-09 36.6 0.0 1.2e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 PRP75845.1 - 2.9e-07 31.0 0.1 0.00013 22.4 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 PRP75845.1 - 1.9e-06 27.7 0.0 0.00018 21.2 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 PRP75845.1 - 2.7e-06 27.4 0.1 1.1e-05 25.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP75845.1 - 1.1e-05 25.7 0.5 0.0052 17.1 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 PRP75845.1 - 3.1e-05 24.0 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP75845.1 - 3.2e-05 24.5 0.0 6.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PRP75845.1 - 3.6e-05 23.2 0.1 0.026 13.9 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 PRP75845.1 - 0.00037 20.6 0.0 0.0011 19.0 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain CPT PF07931.12 PRP75845.1 - 0.00085 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 PRP75845.1 - 0.0028 17.4 0.3 0.03 14.0 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP75845.1 - 0.0029 17.9 0.6 2.7 8.3 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 PRP75845.1 - 0.0037 17.0 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP75845.1 - 0.0041 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DNA_pol3_delta2 PF13177.6 PRP75845.1 - 0.0055 16.5 0.1 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_33 PF13671.6 PRP75845.1 - 0.0066 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 PRP75845.1 - 0.0089 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein IstB_IS21 PF01695.17 PRP75845.1 - 0.0099 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.15 PRP75845.1 - 0.01 15.8 0.0 2.3 8.2 0.1 2.3 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 PRP75845.1 - 0.013 14.7 0.0 0.027 13.7 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain Dehydratase_SU PF02287.15 PRP75845.1 - 0.017 15.2 0.2 0.032 14.3 0.2 1.3 1 0 0 1 1 1 0 Dehydratase small subunit AAA_3 PF07726.11 PRP75845.1 - 0.024 14.5 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 PRP75845.1 - 0.032 13.6 0.1 5.9 6.3 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 PRP75845.1 - 0.037 14.4 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 PRP75845.1 - 0.039 14.4 0.0 0.092 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 PRP75845.1 - 0.048 13.4 0.3 1.7 8.4 0.0 2.8 1 1 2 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 PRP75845.1 - 0.086 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 PRP75845.1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 cobW PF02492.19 PRP75845.1 - 0.11 12.0 0.1 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Vps51 PF08700.11 PRP75850.1 - 6.6e-12 45.3 2.3 6.6e-12 45.3 2.3 3.3 4 0 0 4 4 4 1 Vps51/Vps67 Sec5 PF15469.6 PRP75850.1 - 0.0019 18.0 0.6 0.19 11.5 0.0 3.0 2 0 0 2 2 2 2 Exocyst complex component Sec5 Clr2 PF10383.9 PRP75850.1 - 0.023 15.5 0.5 0.16 12.7 0.1 2.5 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 PI3_PI4_kinase PF00454.27 PRP75851.1 - 1.9e-51 175.3 0.0 7.8e-51 173.3 0.0 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 PRP75851.1 - 1.2e-38 133.1 2.0 4.6e-38 131.2 2.0 2.2 1 0 0 1 1 1 1 NUC194 domain FAT PF02259.23 PRP75851.1 - 2.2e-15 56.7 12.3 7.7e-15 54.9 12.3 1.9 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 PRP75851.1 - 1.7e-11 43.7 0.4 4.5e-11 42.4 0.4 1.8 1 0 0 1 1 1 1 FATC domain RIX1 PF08167.12 PRP75851.1 - 6.4e-05 22.8 1.2 1.1 9.0 0.3 5.2 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 PRP75851.1 - 0.0057 16.8 9.2 41 4.8 0.0 7.0 7 0 0 7 7 7 0 HEAT repeat MIT PF04212.18 PRP75851.1 - 0.15 12.2 4.3 0.33 11.0 0.2 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 PRP75851.1 - 0.78 10.0 4.6 3.3 8.1 0.6 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TolA_bind_tri PF16331.5 PRP75851.1 - 4.2 7.5 9.0 13 5.9 0.0 3.9 4 0 0 4 4 4 0 TolA binding protein trimerisation Sin_N PF04801.13 PRP75852.1 - 4.5e-66 223.8 9.5 7.9e-66 223.0 9.5 1.3 1 0 0 1 1 1 1 Sin-like protein conserved region TTc_toxin_rep PF18807.1 PRP75853.1 - 0.13 12.1 0.0 0.59 10.0 0.0 1.9 2 0 0 2 2 2 0 Tripartite Tc toxins repeat gag-asp_proteas PF13975.6 PRP75856.1 - 2.7e-06 27.9 0.0 6.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 PRP75856.1 - 8e-06 26.4 0.0 2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC_3 PF13917.6 PRP75856.1 - 0.15 12.1 1.0 20 5.2 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L37e PF01907.19 PRP75856.1 - 1.3 9.2 3.0 40 4.5 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e RVT_1 PF00078.27 PRP75857.1 - 2e-23 83.1 0.3 2.8e-23 82.6 0.3 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pectate_lyase_3 PF12708.7 PRP75858.1 - 4.4e-27 95.3 6.9 5.4e-19 68.9 2.4 2.7 2 1 1 3 3 3 2 Pectate lyase superfamily protein Beta_helix PF13229.6 PRP75858.1 - 0.0082 16.0 3.0 0.033 14.0 3.1 1.8 1 1 0 1 1 1 1 Right handed beta helix region Wound_ind PF08186.11 PRP75858.1 - 0.011 16.2 1.8 0.84 10.1 0.2 2.6 2 0 0 2 2 2 0 Wound-inducible basic protein family PDR_assoc PF08370.11 PRP75860.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated 7TMR-HDED PF07697.11 PRP75867.1 - 0.031 14.4 0.1 0.056 13.6 0.1 1.3 1 0 0 1 1 1 0 7TM-HD extracellular KCT2 PF17818.1 PRP75868.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Keratinocyte-associated gene product MCPsignal PF00015.21 PRP75869.1 - 0.00046 20.1 0.0 0.00057 19.7 0.0 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2459 PF09601.10 PRP75869.1 - 0.13 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) VirE PF05272.11 PRP75871.1 - 4.1e-06 26.7 0.0 0.00087 19.1 0.0 2.5 1 1 1 2 2 2 2 Virulence-associated protein E VP4_haemagglut PF00426.18 PRP75871.1 - 0.0065 16.7 0.5 0.085 13.1 0.0 2.7 3 0 0 3 3 3 1 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain DAP3 PF10236.9 PRP75871.1 - 0.0073 15.5 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 PRP75871.1 - 0.0082 15.9 0.0 3.3 7.5 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain KAP_NTPase PF07693.14 PRP75871.1 - 0.013 14.8 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Zeta_toxin PF06414.12 PRP75871.1 - 0.1 11.9 0.0 7.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.6 PRP75871.1 - 0.15 12.4 0.0 2.3 8.6 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain DHHC PF01529.20 PRP75873.1 - 7.7e-14 52.0 4.3 7.7e-14 52.0 4.3 2.5 3 0 0 3 3 3 1 DHHC palmitoyltransferase Gaa1 PF04114.14 PRP75873.1 - 0.81 8.6 5.4 0.042 12.9 0.4 1.4 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component XRCC4 PF06632.12 PRP75874.1 - 0.0017 17.3 4.3 0.0017 17.3 4.3 1.7 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 YlqD PF11068.8 PRP75874.1 - 1.2 9.6 14.4 8.5 6.8 0.6 3.2 3 0 0 3 3 3 0 YlqD protein adh_short PF00106.25 PRP75875.1 - 7.4e-37 126.7 1.3 1.4e-35 122.5 1.3 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP75875.1 - 6.6e-23 81.5 0.6 1.2e-19 70.9 0.3 2.7 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP75875.1 - 7.2e-08 32.5 4.7 5.9e-06 26.3 4.7 2.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PRP75875.1 - 1.7e-05 24.2 0.2 2.7e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 PRP75875.1 - 0.0018 17.3 0.2 0.0031 16.5 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PRP75875.1 - 0.011 15.3 0.3 0.017 14.6 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 PRP75875.1 - 0.015 15.4 1.4 0.024 14.7 1.4 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 PRP75875.1 - 0.02 15.6 0.0 0.053 14.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 PRP75875.1 - 0.041 13.1 0.3 0.066 12.4 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 PRP75875.1 - 0.094 12.6 0.8 0.14 12.0 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CBFB_NFYA PF02045.15 PRP75876.1 - 1.2e-05 25.8 6.3 4.1e-05 24.1 6.3 2.1 1 1 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B CarboxypepD_reg PF13620.6 PRP75877.1 - 3.2e-51 171.5 9.8 1.6e-09 37.9 0.1 10.7 10 0 0 10 10 10 8 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 PRP75877.1 - 5.2e-32 110.4 7.9 0.00012 22.3 0.0 10.7 9 2 2 11 11 11 6 SdrD B-like domain DUF2012 PF09430.10 PRP75877.1 - 1.9e-23 82.9 6.7 0.00043 20.4 0.0 9.5 7 3 1 9 9 9 4 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 PRP75877.1 - 2.3e-22 78.8 4.5 2.8e-06 27.2 0.0 9.0 9 0 0 9 9 9 3 CarboxypepD_reg-like domain SpaA PF17802.1 PRP75877.1 - 1.8e-15 57.0 0.3 0.027 14.8 0.0 8.3 7 2 1 8 8 8 3 Prealbumin-like fold domain fn3_3 PF14686.6 PRP75877.1 - 7.2e-10 38.5 0.5 0.0065 16.2 0.0 6.8 8 0 0 8 8 8 2 Polysaccharide lyase family 4, domain II Dioxygenase_C PF00775.21 PRP75877.1 - 2.8e-07 30.2 0.0 3.1 7.2 0.0 6.4 5 1 1 6 6 6 1 Dioxygenase TTR-52 PF01060.23 PRP75877.1 - 1.4e-06 28.9 0.9 1.7 9.4 0.0 6.1 6 0 0 6 6 6 1 Transthyretin-like family bMG3 PF11974.8 PRP75877.1 - 5.4e-06 26.4 0.2 0.15 12.1 0.0 5.8 7 0 0 7 7 7 1 Bacterial alpha-2-macroglobulin MG3 domain DUF4198 PF10670.9 PRP75877.1 - 3.2e-05 24.4 0.1 0.15 12.4 0.0 5.0 6 1 0 6 6 6 1 Domain of unknown function (DUF4198) Y_Y_Y PF07495.13 PRP75877.1 - 0.00074 19.4 0.0 11 6.0 0.0 4.9 7 0 0 7 7 5 1 Y_Y_Y domain fn3 PF00041.21 PRP75877.1 - 0.00075 19.8 0.1 0.52 10.7 0.0 4.3 4 0 0 4 4 4 1 Fibronectin type III domain Big_1 PF02369.16 PRP75877.1 - 0.0016 18.4 4.6 2.5 8.2 0.0 5.1 5 0 0 5 5 5 2 Bacterial Ig-like domain (group 1) MetallophosN PF16371.5 PRP75877.1 - 0.0061 16.8 1.1 4.6 7.6 0.1 5.6 7 0 0 7 7 7 1 N terminal of Calcineurin-like phosphoesterase EMP24_GP25L PF01105.24 PRP75877.1 - 0.077 12.9 3.0 2.7 7.9 0.0 3.9 2 1 2 4 4 4 0 emp24/gp25L/p24 family/GOLD HSP70 PF00012.20 PRP75878.1 - 8.9e-262 869.6 7.7 1e-261 869.4 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP75878.1 - 7.4e-15 54.6 0.1 1e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 PRP75878.1 - 0.0009 18.3 0.3 0.03 13.3 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 PRP75878.1 - 0.011 15.5 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 PRP75878.1 - 0.017 14.6 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 PRP75878.1 - 0.051 12.8 0.2 0.18 11.0 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PV-1 PF06637.11 PRP75878.1 - 0.25 10.1 6.2 0.45 9.3 6.2 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PEMT PF04191.13 PRP75879.1 - 3.2e-05 24.3 1.7 0.00011 22.5 1.7 2.0 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 PRP75879.1 - 6.1e-05 22.7 0.7 9.5e-05 22.0 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 PRP75879.1 - 0.0076 16.7 0.2 0.023 15.1 0.2 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family UPF0552 PF10574.9 PRP75880.1 - 7.1e-13 48.4 3.8 2.4e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 Arp2/3-interacting proteins Arpin FHA PF00498.26 PRP75880.1 - 0.1 13.0 0.0 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 FHA domain Pkinase PF00069.25 PRP75882.1 - 3.3e-42 144.7 3.6 3.7e-42 144.5 3.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75882.1 - 4.9e-30 104.7 1.6 5.6e-30 104.5 1.6 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP75882.1 - 0.00099 19.1 0.0 0.14 12.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP75882.1 - 0.0065 15.8 1.2 0.023 14.0 0.6 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 PRP75882.1 - 0.025 14.2 0.3 0.032 13.8 0.3 1.1 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 PRP75882.1 - 0.035 12.9 0.4 0.038 12.8 0.4 1.3 1 1 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PRP75882.1 - 0.042 12.8 0.4 0.052 12.5 0.4 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pex2_Pex12 PF04757.14 PRP75883.1 - 6.4e-27 94.6 11.5 8.4e-27 94.2 11.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 PRP75883.1 - 2.3e-05 24.1 3.7 4.2e-05 23.3 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP75883.1 - 0.00019 21.2 2.7 0.00036 20.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP75883.1 - 0.0067 16.3 2.6 0.011 15.6 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP75883.1 - 0.0085 16.4 2.0 0.014 15.7 2.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PRP75883.1 - 0.1 12.6 4.0 0.23 11.4 4.0 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PRP75883.1 - 0.25 11.6 4.1 0.45 10.7 4.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PRP75883.1 - 0.97 9.5 4.1 2.1 8.4 4.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Complex1_LYR PF05347.15 PRP75885.1 - 4.7e-09 36.2 2.1 8.8e-09 35.3 2.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PRP75885.1 - 0.00019 22.1 0.5 0.00022 21.9 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 PRP75885.1 - 0.024 15.2 0.5 0.035 14.7 0.5 1.3 1 1 0 1 1 1 0 Complex1_LYR-like Corona_5a PF06336.11 PRP75885.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Coronavirus 5a protein Eapp_C PF10238.9 PRP75886.1 - 3.6e-38 131.0 13.0 3.6e-38 131.0 13.0 2.3 2 1 0 2 2 2 1 E2F-associated phosphoprotein Lge1 PF11488.8 PRP75887.1 - 0.039 14.1 0.2 0.039 14.1 0.2 5.5 6 1 0 6 6 6 0 Transcriptional regulatory protein LGE1 DUF2730 PF10805.8 PRP75887.1 - 0.25 11.5 25.5 0.17 12.0 1.4 6.3 4 4 2 6 6 6 0 Protein of unknown function (DUF2730) Hydantoinase_B PF02538.14 PRP75887.1 - 0.44 8.9 3.7 0.12 10.8 0.3 1.7 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase DUF4795 PF16043.5 PRP75888.1 - 7.3e-07 29.0 3.6 5.4e-06 26.2 3.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) DUF3454 PF11936.8 PRP75888.1 - 0.11 12.9 0.1 0.11 12.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3454) CG-1 PF03859.16 PRP75889.1 - 0.055 13.2 0.1 0.084 12.7 0.1 1.3 1 0 0 1 1 1 0 CG-1 domain LsmAD PF06741.13 PRP75890.1 - 2e-24 85.9 3.0 2e-24 85.9 3.0 3.9 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.6 PRP75890.1 - 1e-19 70.5 1.8 1.3e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 PRP75890.1 - 0.0012 18.9 0.0 0.0041 17.2 0.0 1.9 1 0 0 1 1 1 1 Scd6-like Sm domain PAM2 PF07145.15 PRP75890.1 - 0.011 15.4 0.7 0.011 15.4 0.7 2.4 2 0 0 2 2 2 0 Ataxin-2 C-terminal region LSM PF01423.22 PRP75890.1 - 0.21 11.3 0.0 0.48 10.1 0.0 1.6 1 0 0 1 1 1 0 LSM domain Chalcone_2 PF16035.5 PRP75891.1 - 2.8e-17 63.2 0.0 1.6e-15 57.5 0.0 2.3 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 PRP75891.1 - 3.5e-05 24.0 0.0 0.00048 20.3 0.0 2.1 1 1 0 1 1 1 1 Chalcone isomerase-like Pkinase PF00069.25 PRP75892.1 - 9.5e-35 120.2 0.1 2.9e-34 118.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP75892.1 - 9.7e-24 84.0 0.0 2.1e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 PRP75892.1 - 5e-17 62.0 0.4 1e-16 60.9 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP75892.1 - 4.9e-05 23.5 0.1 0.0002 21.6 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP75892.1 - 0.00016 21.1 0.0 0.00051 19.5 0.0 1.8 1 0 0 1 1 1 1 ADP-ribosylation factor family PCRF PF03462.18 PRP75892.1 - 0.00064 19.6 1.6 0.0014 18.5 1.6 1.5 1 0 0 1 1 1 1 PCRF domain RPW8 PF05659.11 PRP75892.1 - 0.077 12.7 1.5 0.19 11.4 1.5 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Rx_N PF18052.1 PRP75892.1 - 0.13 12.6 1.3 0.32 11.3 1.3 1.6 1 0 0 1 1 1 0 Rx N-terminal domain Mod_r PF07200.13 PRP75892.1 - 0.14 12.2 8.4 0.053 13.6 5.2 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OmpH PF03938.14 PRP75892.1 - 0.18 12.1 6.5 0.37 11.1 6.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-FPG_IleRS PF06827.14 PRP75893.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF2855 PF11017.8 PRP75893.1 - 0.71 9.6 10.3 0.47 10.2 7.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) TRM PF02005.16 PRP75893.1 - 5.3 6.1 8.1 0.41 9.7 3.4 1.5 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase FHA PF00498.26 PRP75894.1 - 2.6e-16 59.7 0.0 5.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PRP75894.1 - 6e-11 42.5 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain OCRE PF17780.1 PRP75894.1 - 1.2 9.3 13.0 1.1 9.4 1.3 3.2 2 1 0 2 2 2 0 OCRE domain Imm53 PF15580.6 PRP75897.1 - 0.015 15.0 1.7 0.015 15.0 0.1 1.8 2 0 0 2 2 2 0 Immunity protein 53 FBP_C PF16571.5 PRP75897.1 - 0.025 14.1 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger WD40 PF00400.32 PRP75898.1 - 1.4e-06 28.9 0.2 7.8e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP75898.1 - 0.076 13.3 0.0 0.082 13.2 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain FAD_binding_3 PF01494.19 PRP75900.1 - 7.9e-35 120.7 0.1 1.2e-34 120.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP75900.1 - 5.6e-09 35.6 0.8 0.0022 17.3 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP75900.1 - 0.00025 20.7 3.5 0.012 15.2 0.0 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase SE PF08491.10 PRP75900.1 - 0.00043 19.4 0.0 0.018 14.1 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 PRP75900.1 - 0.001 18.2 0.5 0.0061 15.7 0.1 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 PRP75900.1 - 0.0022 17.3 4.0 0.61 9.3 1.5 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP75900.1 - 0.0023 18.1 0.2 0.0049 17.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PRP75900.1 - 0.003 18.1 1.3 1.4 9.5 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP75900.1 - 0.0074 15.4 4.1 0.035 13.2 0.9 2.5 2 1 1 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 PRP75900.1 - 0.029 13.7 0.8 0.11 11.8 0.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP75900.1 - 0.054 12.2 0.7 4.9 5.7 0.5 2.3 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 PRP75900.1 - 1.8 8.5 5.7 7.8 6.5 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Csm2_III-A PF03750.13 PRP75902.1 - 0.089 13.6 0.0 0.24 12.3 0.0 1.7 1 0 0 1 1 1 0 Csm2 Type III-A LSM PF01423.22 PRP75903.1 - 5.3e-16 58.1 0.3 6.1e-16 57.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain HPS3_Mid PF14762.6 PRP75904.1 - 4.7e-27 94.8 3.8 4.7e-27 94.8 3.8 2.8 2 2 1 3 3 3 1 Hermansky-Pudlak syndrome 3, middle region HPS3_C PF14763.6 PRP75904.1 - 0.015 14.7 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, C-terminal TPR_2 PF07719.17 PRP75906.1 - 3.9e-19 67.1 18.0 0.47 10.7 0.0 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 PRP75906.1 - 1.5e-15 56.2 23.2 0.077 12.8 0.1 10.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 PRP75906.1 - 9.1e-13 47.9 8.1 0.14 13.1 0.1 8.1 7 2 2 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP75906.1 - 5e-12 45.0 19.9 0.024 14.8 0.1 10.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP75906.1 - 1.4e-11 44.7 11.4 0.36 11.4 0.3 6.7 6 1 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 PRP75906.1 - 4e-09 36.6 10.8 0.091 13.1 0.0 7.5 6 3 1 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP75906.1 - 3.6e-08 33.5 10.3 0.066 13.4 0.0 5.7 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 PRP75906.1 - 2e-06 27.5 4.2 0.37 10.7 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP75906.1 - 1.4e-05 25.7 0.1 18 6.1 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP75906.1 - 3.4e-05 23.6 8.6 0.32 11.1 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP75906.1 - 0.00016 21.8 7.3 2.4 8.3 0.5 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP75906.1 - 0.00078 19.1 0.3 3.1 7.6 0.0 5.4 5 1 1 6 6 6 1 TPR repeat TPR_15 PF13429.6 PRP75906.1 - 0.0028 16.9 1.1 0.0028 16.9 1.1 4.8 3 2 3 6 6 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PRP75906.1 - 0.0036 17.3 7.0 2.8 8.0 0.4 4.8 3 1 2 5 5 5 1 Putative TPR-like repeat TPR_17 PF13431.6 PRP75906.1 - 0.052 13.9 1.2 6.6 7.4 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP75906.1 - 0.062 12.7 7.9 0.12 11.7 0.7 3.8 2 2 1 3 3 3 0 MalT-like TPR region TPR_20 PF14561.6 PRP75906.1 - 0.12 12.7 3.6 7.9 6.9 0.1 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 PRP75906.1 - 0.44 11.3 2.1 39 5.1 0.0 3.1 3 0 0 3 3 2 0 Sel1 repeat ERO1 PF04137.15 PRP75907.1 - 6.7e-15 55.1 0.1 7.5e-15 55.0 0.1 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Actin PF00022.19 PRP75908.1 - 1.3e-73 248.0 0.0 1.4e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Actin SPRY PF00622.28 PRP75909.1 - 1.8e-13 50.6 0.0 3.7e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 PRP75909.1 - 2.9e-12 46.3 0.6 2.9e-12 46.3 0.6 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP75909.1 - 2.1e-08 33.8 2.5 2.1e-08 33.8 2.5 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 PRP75909.1 - 0.082 12.8 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 F-box CLASP_N PF12348.8 PRP75910.1 - 1.2e-05 25.0 0.1 1.8e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 PRP75910.1 - 0.005 17.0 0.1 16 6.1 0.0 3.9 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 PRP75910.1 - 0.057 13.8 0.0 3.5 8.1 0.0 3.0 2 1 0 3 3 3 0 HEAT repeats IBR PF01485.21 PRP75912.1 - 1.1e-15 57.6 46.3 5.2e-09 36.2 8.2 4.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain UBA_4 PF14555.6 PRP75912.1 - 1.9e-05 24.4 0.0 0.061 13.2 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain RWD PF05773.22 PRP75912.1 - 0.0061 16.8 0.1 0.023 15.0 0.1 2.0 1 0 0 1 1 1 1 RWD domain zf-RING_UBOX PF13445.6 PRP75912.1 - 0.011 15.8 1.7 0.011 15.8 1.7 3.8 3 0 0 3 3 3 0 RING-type zinc-finger Nore1-SARAH PF16517.5 PRP75912.1 - 0.025 14.5 0.3 0.075 12.9 0.3 1.8 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain CUE PF02845.16 PRP75912.1 - 0.026 14.2 0.4 35 4.2 0.0 3.6 3 0 0 3 3 3 0 CUE domain Cofilin_ADF PF00241.20 PRP75913.1 - 2.2e-16 59.7 0.0 2.7e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAA_22 PF13401.6 PRP75916.1 - 0.002 18.4 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PRP75916.1 - 0.085 12.8 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Rpn9_C PF18261.1 PRP75917.1 - 0.015 14.8 1.1 2.6 7.7 0.2 2.5 2 0 0 2 2 2 0 Rpn9 C-terminal helix DUF2533 PF10752.9 PRP75917.1 - 0.053 14.0 1.2 0.16 12.5 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2533) DUF3927 PF13064.6 PRP75921.1 - 0.12 12.4 1.6 0.21 11.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) LAP1C PF05609.12 PRP75922.1 - 3 6.8 10.2 4.2 6.4 10.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ank_4 PF13637.6 PRP75923.1 - 8.7e-06 26.2 0.0 1.9e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP75923.1 - 5.1e-05 23.8 0.0 8.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP75923.1 - 0.001 19.3 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP75923.1 - 0.017 15.6 0.0 2.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 PRP75923.1 - 0.17 12.5 0.0 2.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat DHC_N2 PF08393.13 PRP75924.1 - 0.21 10.6 0.0 0.36 9.9 0.0 1.3 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 PGC7_Stella PF15549.6 PRP75926.1 - 0.61 10.1 4.3 0.52 10.3 0.4 2.2 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain HECT PF00632.25 PRP75927.1 - 2.9e-36 125.5 0.0 5.6e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Dynamin_N PF00350.23 PRP75927.1 - 4.3e-13 49.6 0.0 1.3e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 PRP75927.1 - 0.00019 21.5 0.0 0.0014 18.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 PRP75927.1 - 0.0035 16.5 0.1 2 7.4 0.0 2.4 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 PRP75927.1 - 0.0052 16.7 0.9 1.8 8.5 0.3 3.3 3 0 0 3 3 3 1 RsgA GTPase Ank_2 PF12796.7 PRP75927.1 - 0.13 12.9 0.1 0.76 10.4 0.1 2.3 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Roc PF08477.13 PRP75927.1 - 0.13 12.5 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 PRP75927.1 - 0.16 12.5 0.0 0.56 10.7 0.0 2.0 1 0 0 1 1 1 0 ABC transporter CD52 PF15116.6 PRP75929.1 - 0.15 12.1 0.6 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 CAMPATH-1 antigen DUF4337 PF14235.6 PRP75930.1 - 0.016 15.3 1.6 0.016 15.3 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Nop25 PF09805.9 PRP75930.1 - 0.056 13.9 6.0 0.061 13.8 6.0 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1948 PF09185.10 PRP75930.1 - 0.069 13.0 0.4 0.069 13.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) K_trans PF02705.16 PRP75931.1 - 1.1e-11 44.0 0.9 1.3e-11 43.7 0.9 1.1 1 0 0 1 1 1 1 K+ potassium transporter WRKY PF03106.15 PRP75932.1 - 0.16 12.2 1.1 0.42 10.9 1.1 1.8 1 0 0 1 1 1 0 WRKY DNA -binding domain WRKY PF03106.15 PRP75933.1 - 0.18 12.1 0.4 0.38 11.0 0.4 1.5 1 0 0 1 1 1 0 WRKY DNA -binding domain Homeodomain PF00046.29 PRP75934.1 - 1.4e-13 50.4 8.9 8.9e-07 28.7 0.6 3.2 3 0 0 3 3 3 2 Homeodomain Homez PF11569.8 PRP75934.1 - 0.0009 18.7 0.5 0.03 13.8 0.1 2.3 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 PRP75934.1 - 0.017 15.0 4.5 2 8.4 0.4 3.0 3 0 0 3 3 3 0 Homeobox KN domain YdaS_antitoxin PF15943.5 PRP75934.1 - 0.028 14.3 0.6 0.66 9.9 0.0 2.7 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT LepB_GAP_N PF18172.1 PRP75934.1 - 0.081 12.8 0.6 0.21 11.5 0.6 1.7 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain BHD_2 PF10404.9 PRP75934.1 - 6.7 7.8 24.7 24 5.9 15.7 3.9 2 1 1 3 3 3 0 Rad4 beta-hairpin domain 2 HTH_3 PF01381.22 PRP75935.1 - 0.0001 22.3 0.1 0.11 12.6 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix Homeodomain PF00046.29 PRP75935.1 - 0.00026 20.8 2.3 0.26 11.2 0.1 2.9 3 0 0 3 3 3 2 Homeodomain HTH_28 PF13518.6 PRP75935.1 - 0.002 18.2 0.9 0.069 13.3 0.2 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 PRP75935.1 - 0.0038 17.2 0.1 0.61 10.1 0.0 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain InPase PF18823.1 PRP75935.1 - 0.01 15.5 2.6 0.01 15.5 2.6 2.1 2 0 0 2 2 2 0 Inorganic Pyrophosphatase Homeobox_KN PF05920.11 PRP75935.1 - 0.024 14.5 0.4 0.32 10.9 0.1 2.6 2 1 0 2 2 2 0 Homeobox KN domain MerR PF00376.23 PRP75935.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 MerR family regulatory protein HTH_26 PF13443.6 PRP75935.1 - 0.055 13.9 1.7 3.1 8.3 0.0 3.2 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain DUF2170 PF09938.9 PRP75935.1 - 0.057 13.1 0.6 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) YdaS_antitoxin PF15943.5 PRP75935.1 - 0.11 12.3 0.6 0.59 10.0 0.0 2.3 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT NYD-SP28_assoc PF14775.6 PRP75935.1 - 0.47 10.6 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain Homeodomain PF00046.29 PRP75936.1 - 7e-51 169.9 43.7 4.2e-07 29.7 0.7 9.1 8 0 0 8 8 8 8 Homeodomain YdaS_antitoxin PF15943.5 PRP75936.1 - 1.5e-13 50.4 3.5 0.061 13.2 0.0 6.3 6 0 0 6 6 6 4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 PRP75936.1 - 1.8e-10 40.5 29.9 0.18 11.7 0.3 9.2 9 0 0 9 9 9 6 Homeobox KN domain Phage_CI_repr PF07022.13 PRP75936.1 - 0.00037 20.5 0.2 0.18 11.9 0.0 3.0 3 0 0 3 3 3 2 Bacteriophage CI repressor helix-turn-helix domain Homez PF11569.8 PRP75936.1 - 0.0004 19.8 14.7 0.63 9.5 0.0 7.5 8 0 0 8 8 8 1 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.6 PRP75936.1 - 0.83 10.1 21.6 14 6.2 0.2 8.0 9 0 0 9 9 9 0 Cro/C1-type HTH DNA-binding domain ADH_zinc_N_2 PF13602.6 PRP75938.1 - 3.5e-25 89.6 0.0 6.8e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PRP75938.1 - 4.2e-17 62.3 0.0 7.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP75938.1 - 4e-08 33.1 0.0 1.4e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 PRP75938.1 - 0.097 13.1 0.5 0.3 11.6 0.5 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_N_2 PF16884.5 PRP75938.1 - 0.45 10.4 1.5 1.4 8.8 0.1 2.4 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase Hexokinase_2 PF03727.16 PRP75939.1 - 6.2e-72 241.9 0.1 8.3e-72 241.5 0.1 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 PRP75939.1 - 9.5e-66 221.5 0.0 1.5e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase TPP_enzyme_N PF02776.18 PRP75939.1 - 0.055 13.1 0.2 0.094 12.3 0.2 1.3 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain HLH PF00010.26 PRP75940.1 - 4.9e-13 48.8 4.6 9.1e-13 48.0 4.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Poty_PP PF08440.10 PRP75940.1 - 0.018 14.1 0.2 0.026 13.6 0.2 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein ZapB PF06005.12 PRP75940.1 - 0.31 11.5 5.0 0.12 12.8 0.8 2.2 2 0 0 2 2 2 0 Cell division protein ZapB PAP2 PF01569.21 PRP75941.1 - 3.5e-15 56.0 7.8 3.5e-15 56.0 7.8 2.4 2 1 0 2 2 2 1 PAP2 superfamily PhoLip_ATPase_C PF16212.5 PRP75941.1 - 1.4 8.6 10.3 0.13 12.0 5.0 1.7 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal Homeodomain PF00046.29 PRP75942.1 - 1.8e-09 37.3 4.4 7.2e-05 22.6 0.2 2.6 2 0 0 2 2 2 2 Homeodomain YdaS_antitoxin PF15943.5 PRP75942.1 - 0.01 15.7 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR PF00376.23 PRP75942.1 - 0.022 14.5 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 MerR family regulatory protein Homeobox_KN PF05920.11 PRP75942.1 - 0.038 13.9 0.3 5.2 7.0 0.0 2.7 2 0 0 2 2 2 0 Homeobox KN domain CDC45 PF02724.14 PRP75942.1 - 2.1 6.5 30.0 2.9 6.1 30.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 PRP75942.1 - 5.5 5.7 24.9 8.5 5.0 24.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Kinesin PF00225.23 PRP75943.1 - 1.3e-106 356.3 0.5 1.3e-106 356.3 0.5 3.3 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PRP75943.1 - 4.6e-24 85.1 0.0 4.6e-24 85.1 0.0 3.3 3 0 0 3 3 3 1 Microtubule binding HMMR_C PF15908.5 PRP75943.1 - 4.6e-05 23.7 16.5 4.6e-05 23.7 16.5 7.3 2 2 4 7 7 7 1 Hyaluronan mediated motility receptor C-terminal ATG16 PF08614.11 PRP75943.1 - 0.0063 16.8 22.6 0.0063 16.8 22.6 9.3 1 1 8 9 9 9 4 Autophagy protein 16 (ATG16) TrmO PF01980.16 PRP75944.1 - 6.1e-37 126.5 0.0 8.5e-37 126.0 0.0 1.2 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 PRP75944.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 TrmO C-terminal domain Amidohydro_1 PF01979.20 PRP75947.1 - 3.3e-65 220.7 0.0 4.2e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PRP75947.1 - 9e-12 45.2 3.1 2.7e-10 40.3 0.0 3.0 2 1 1 3 3 3 2 Amidohydrolase family DUF4363 PF14276.6 PRP75947.1 - 2 8.6 7.5 0.23 11.6 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) CLU PF13236.6 PRP75948.1 - 3e-50 171.1 0.0 6.3e-50 170.1 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria TPR_12 PF13424.6 PRP75948.1 - 4.5e-30 103.7 13.2 9.4e-11 41.9 0.7 5.8 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 PRP75948.1 - 3.1e-14 52.3 19.9 0.0034 17.2 0.7 7.0 8 0 0 8 8 8 5 Tetratricopeptide repeat eIF3_p135 PF12807.7 PRP75948.1 - 4e-10 40.0 0.1 1.9e-09 37.8 0.0 2.2 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit 135 TPR_MalT PF17874.1 PRP75948.1 - 6.8e-09 35.6 4.5 1.2e-07 31.4 0.4 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 PRP75948.1 - 2e-07 30.6 9.8 0.19 11.9 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP75948.1 - 6e-06 25.9 6.5 0.051 13.6 0.0 5.2 7 0 0 7 7 5 2 Tetratricopeptide repeat ANAPC5 PF12862.7 PRP75948.1 - 0.00044 20.3 2.9 0.024 14.7 0.3 3.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 PRP75948.1 - 0.00052 20.0 10.2 18 5.9 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP75948.1 - 0.0023 17.7 6.8 2.5 8.1 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 PRP75948.1 - 0.0031 16.9 0.0 0.044 13.2 0.0 2.7 2 0 0 2 2 2 1 SHNi-TPR TPR_14 PF13428.6 PRP75948.1 - 0.0045 17.7 5.2 11 7.1 0.0 5.2 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP75948.1 - 0.0066 16.9 6.4 0.45 11.1 0.1 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 PRP75948.1 - 0.022 14.2 7.6 0.024 14.1 1.3 2.8 1 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 PRP75948.1 - 0.12 12.0 8.9 0.67 9.6 0.3 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain PNPase PF03726.14 PRP75948.1 - 0.98 10.0 11.2 0.28 11.7 0.2 4.4 4 0 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain RSN1_7TM PF02714.15 PRP75949.1 - 1.6e-48 165.4 24.9 3.1e-48 164.4 24.9 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 PRP75949.1 - 6.6e-18 65.6 0.0 1e-17 64.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 PRP75949.1 - 7.1e-16 58.4 6.3 4.1e-11 42.9 0.1 3.7 4 1 0 4 4 4 2 Late exocytosis, associated with Golgi transport Steroid_dh PF02544.16 PRP75951.1 - 1.9e-36 125.3 0.1 3.5e-36 124.4 0.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ank_5 PF13857.6 PRP75951.1 - 2.8e-18 65.8 1.7 6.9e-11 42.2 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP75951.1 - 2e-17 63.5 0.2 2.4e-07 31.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75951.1 - 6.7e-16 58.4 3.8 5.2e-07 30.1 0.0 4.6 2 1 3 5 5 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP75951.1 - 4.2e-15 55.4 6.9 1.1e-06 28.8 0.0 4.4 5 0 0 5 5 4 3 Ankyrin repeat Ank_3 PF13606.6 PRP75951.1 - 4.4e-11 42.0 0.0 0.00014 22.0 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat F5_F8_type_C PF00754.25 PRP75951.1 - 1e-09 38.6 0.0 1.1e-08 35.2 0.0 2.6 2 1 0 2 2 2 1 F5/8 type C domain DUF1295 PF06966.12 PRP75951.1 - 0.0015 18.1 0.3 0.0032 17.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 PRP75951.1 - 0.0076 16.6 0.7 0.016 15.6 0.1 1.8 2 0 0 2 2 1 1 Phospholipid methyltransferase RAP1 PF07218.11 PRP75951.1 - 0.24 9.6 10.6 0.34 9.1 10.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nucleo_P87 PF07267.11 PRP75951.1 - 0.62 8.8 11.3 0.85 8.4 11.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF908 PF06012.12 PRP75951.1 - 6.6 6.0 8.5 13 5.1 8.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Chromo PF00385.24 PRP75952.1 - 5.7e-14 51.8 0.3 2.2e-13 49.9 0.3 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-4CXXC_R1 PF10497.9 PRP75952.1 - 3.1e-09 36.9 11.1 3.1e-09 36.9 11.1 2.0 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PEHE PF15275.6 PRP75952.1 - 0.0015 19.1 0.6 0.0015 19.1 0.6 2.7 3 0 0 3 3 3 1 PEHE domain CEBP_ZZ PF16366.5 PRP75952.1 - 1.1 9.6 11.6 0.26 11.6 5.5 2.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Homeodomain PF00046.29 PRP75953.1 - 2.8e-16 59.1 1.1 5.9e-16 58.1 1.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP75953.1 - 0.0001 22.1 0.3 0.00023 21.0 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain FAD_binding_3 PF01494.19 PRP75953.1 - 0.15 11.2 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain PDCD2_C PF04194.13 PRP75954.1 - 3.8e-36 124.8 2.1 3.8e-36 124.8 2.1 2.7 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 PRP75954.1 - 2.3e-08 34.0 10.6 2.3e-08 34.0 10.6 3.0 3 1 0 3 3 3 1 MYND finger zf-RING_7 PF02591.15 PRP75954.1 - 0.19 12.0 7.2 0.47 10.7 0.1 3.6 3 0 0 3 3 3 0 C4-type zinc ribbon domain bZIP_1 PF00170.21 PRP75955.1 - 0.027 14.6 2.6 0.027 14.6 2.6 4.7 5 1 1 6 6 6 0 bZIP transcription factor TSC22 PF01166.18 PRP75955.1 - 0.065 13.5 15.8 0.43 10.9 0.6 5.0 4 1 1 5 5 5 0 TSC-22/dip/bun family BCL_N PF04714.13 PRP75955.1 - 0.2 11.7 5.2 0.74 9.9 0.3 3.1 2 0 0 2 2 2 0 BCL7, N-terminal conserver region CENP-F_leu_zip PF10473.9 PRP75955.1 - 1.9 8.5 27.3 1.9 8.5 0.8 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Homeodomain PF00046.29 PRP75956.1 - 2.3e-08 33.7 6.9 0.00021 21.1 1.4 2.3 2 0 0 2 2 2 2 Homeodomain HTH_Tnp_1 PF01527.20 PRP75956.1 - 4e-05 23.9 2.9 0.14 12.5 0.0 3.4 2 1 0 2 2 2 2 Transposase HTH_23 PF13384.6 PRP75956.1 - 0.00016 21.3 0.3 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 Homeodomain-like domain Homeobox_KN PF05920.11 PRP75956.1 - 0.00023 21.0 1.0 0.06 13.3 0.3 2.5 2 0 0 2 2 2 2 Homeobox KN domain HTH_28 PF13518.6 PRP75956.1 - 0.00035 20.6 0.3 0.08 13.1 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain MerR_1 PF13411.6 PRP75956.1 - 0.00046 20.2 0.6 0.036 14.2 0.2 2.3 2 0 0 2 2 2 1 MerR HTH family regulatory protein YdaS_antitoxin PF15943.5 PRP75956.1 - 0.029 14.2 0.0 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_29 PF13551.6 PRP75956.1 - 0.058 13.4 0.1 13 5.9 0.1 2.7 2 1 0 2 2 2 0 Winged helix-turn helix Chitin_bind_1 PF00187.19 PRP75958.1 - 2.7e-07 30.9 17.9 2.7e-07 30.9 17.9 2.9 3 0 0 3 3 3 1 Chitin recognition protein OST3_OST6 PF04756.13 PRP75959.1 - 1.3e-51 175.7 0.8 1.5e-51 175.5 0.8 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 PRP75959.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin ABC2_membrane_5 PF13346.6 PRP75959.1 - 0.034 13.7 3.6 0.09 12.3 3.6 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3995 PF13160.6 PRP75959.1 - 0.24 11.8 3.9 0.33 11.3 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF4181 PF13789.6 PRP75959.1 - 0.42 10.9 4.6 0.72 10.1 0.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4181) Peroxidase_ext PF11895.8 PRP75960.1 - 0.066 13.2 0.1 0.44 10.5 0.0 2.2 3 0 0 3 3 3 0 Fungal peroxidase extension region Dabb PF07876.12 PRP75961.1 - 5.3e-23 81.5 0.0 7.5e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain CLAMP PF14769.6 PRP75964.1 - 2.5e-14 53.5 0.8 5.2e-14 52.5 0.8 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 NOC3p PF07540.11 PRP75965.1 - 3e-24 85.3 0.2 3e-24 85.3 0.2 3.5 4 0 0 4 4 4 1 Nucleolar complex-associated protein CBF PF03914.17 PRP75965.1 - 1.3e-18 67.6 1.2 1.3e-18 67.6 1.2 3.2 2 1 2 4 4 4 1 CBF/Mak21 family SAS-6_N PF16531.5 PRP75965.1 - 0.012 16.2 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 Centriolar protein SAS N-terminal RbsD_FucU PF05025.13 PRP75965.1 - 0.024 15.0 0.7 0.095 13.1 0.2 2.2 2 0 0 2 2 2 0 RbsD / FucU transport protein family SPG48 PF14764.6 PRP75965.1 - 0.078 13.5 4.1 0.39 11.2 0.2 3.1 2 1 1 3 3 3 0 AP-5 complex subunit, vesicle trafficking PIP5K PF01504.18 PRP75966.1 - 4.3e-88 295.1 1.1 3.1e-87 292.3 1.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase NmrA PF05368.13 PRP75967.1 - 4.6e-17 62.4 0.0 7.7e-17 61.6 0.0 1.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP75967.1 - 9.2e-05 22.4 0.0 0.00024 21.1 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 PRP75967.1 - 0.0003 20.7 0.1 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 PRP75967.1 - 0.00032 21.0 0.0 0.00082 19.6 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 PRP75967.1 - 0.0051 16.1 0.1 0.0076 15.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.20 PRP75967.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 PRP75967.1 - 0.054 13.1 0.1 0.11 12.0 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 PRP75967.1 - 0.12 12.7 0.1 0.53 10.6 0.0 2.1 2 1 0 2 2 2 0 TrkA-N domain Lysine_decarbox PF03641.14 PRP75969.1 - 1.3e-34 119.1 0.0 2.2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 PRP75969.1 - 2.5e-14 53.2 0.0 4.1e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Homeodomain PF00046.29 PRP75969.1 - 2.1e-10 40.3 6.0 5.1e-06 26.2 0.7 2.5 2 0 0 2 2 2 2 Homeodomain DUF1233 PF06806.12 PRP75969.1 - 0.0022 17.6 1.1 5.2 6.7 0.1 3.5 3 0 0 3 3 3 2 Putative excisionase (DUF1233) HTH_26 PF13443.6 PRP75969.1 - 0.0054 17.1 0.9 2.9 8.4 0.2 2.4 2 0 0 2 2 2 2 Cro/C1-type HTH DNA-binding domain Homeobox_KN PF05920.11 PRP75969.1 - 0.028 14.3 3.3 3.1 7.8 0.2 2.5 2 0 0 2 2 2 0 Homeobox KN domain Homez PF11569.8 PRP75969.1 - 0.036 13.5 0.4 0.68 9.4 0.0 2.7 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez DUF5419 PF17441.2 PRP75969.1 - 0.044 13.9 0.1 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5419) NUFIP1 PF10453.9 PRP75969.1 - 0.35 10.7 5.6 1.2 9.0 0.7 2.4 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) NAP PF00956.18 PRP75970.1 - 2.1e-64 217.3 0.0 3e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Homeodomain PF00046.29 PRP75971.1 - 2.2e-14 53.0 2.1 5e-14 51.9 2.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP75971.1 - 4.6e-08 32.8 0.1 1.2e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Pox_J1 PF03338.15 PRP75971.1 - 0.17 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus J1 protein BLM10_N PF16547.5 PRP75971.1 - 0.68 10.3 2.7 0.92 9.8 2.1 1.5 1 1 0 1 1 1 0 Proteasome-substrate-size regulator, N-terminal Glucan_synthase PF02364.15 PRP75972.1 - 1.3e-77 261.8 13.3 7.1e-77 259.3 13.3 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 PRP75972.1 - 0.034 14.5 0.0 0.13 12.6 0.0 2.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 AAA_6 PF12774.7 PRP75973.1 - 7.9e-163 541.1 0.0 2.7e-158 526.2 0.0 3.6 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PRP75973.1 - 1.1e-139 465.9 5.1 1.1e-139 465.9 5.1 3.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PRP75973.1 - 6.1e-115 383.7 0.0 4.4e-114 380.8 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PRP75973.1 - 1.2e-95 319.7 0.0 6.7e-95 317.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PRP75973.1 - 1.8e-91 305.2 9.4 7e-91 303.3 2.3 3.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 PRP75973.1 - 1.2e-85 285.6 0.0 1.4e-80 269.1 0.0 4.0 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PRP75973.1 - 3.2e-61 205.9 0.8 3.6e-60 202.5 0.1 2.9 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PRP75973.1 - 3.1e-47 159.5 0.0 3.6e-45 152.9 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 PRP75973.1 - 5.8e-46 157.1 11.8 5.8e-46 157.1 11.8 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 PRP75973.1 - 1.4e-30 106.0 0.0 6.5e-30 103.9 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PRP75973.1 - 9.2e-25 87.2 0.0 4.6e-08 33.2 0.0 5.9 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PRP75973.1 - 3.1e-21 75.5 0.1 1.8e-20 73.0 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 PRP75973.1 - 1.6e-13 51.2 1.1 0.004 17.6 0.0 5.9 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP75973.1 - 2.3e-10 40.9 0.4 0.0078 16.5 0.0 5.1 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 PRP75973.1 - 1.1e-07 32.4 3.0 5.2 7.4 0.0 6.2 5 1 1 6 6 5 0 AAA ATPase domain AAA_18 PF13238.6 PRP75973.1 - 1.7e-07 31.8 0.0 0.23 12.0 0.0 5.4 5 0 0 5 5 4 2 AAA domain RNA_helicase PF00910.22 PRP75973.1 - 8.9e-06 26.1 0.6 0.78 10.2 0.0 4.3 4 0 0 4 4 3 2 RNA helicase AAA_33 PF13671.6 PRP75973.1 - 4.7e-05 23.6 0.1 0.85 9.8 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 PRP75973.1 - 5.7e-05 22.9 0.7 3 7.5 0.1 3.5 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 PRP75973.1 - 9.2e-05 22.1 2.9 1.2 8.7 0.0 4.3 4 0 0 4 4 3 2 SRP54-type protein, GTPase domain ResIII PF04851.15 PRP75973.1 - 0.00026 21.0 0.1 1.7 8.6 0.0 3.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 PRP75973.1 - 0.00036 21.0 0.1 3.9 8.0 0.0 4.3 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.6 PRP75973.1 - 0.0013 18.5 0.6 8.1 6.1 0.0 3.8 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 PRP75973.1 - 0.0038 17.2 0.2 3.2 7.6 0.0 3.8 3 0 0 3 3 3 1 Rad17 P-loop domain RuvB_N PF05496.12 PRP75973.1 - 0.0085 15.8 0.0 6.3 6.5 0.0 3.4 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 PRP75973.1 - 0.0093 16.3 1.0 15 5.9 0.0 3.8 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 PRP75973.1 - 0.011 15.5 0.0 6.2 6.5 0.0 3.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase TsaE PF02367.17 PRP75973.1 - 0.012 15.7 2.9 7.8 6.5 0.0 4.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF853 PF05872.12 PRP75973.1 - 0.02 13.5 5.7 4.8 5.6 0.0 4.3 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF853) Exonuc_VII_L PF02601.15 PRP75973.1 - 0.021 14.4 22.7 0.19 11.3 0.8 3.9 3 0 0 3 3 3 0 Exonuclease VII, large subunit Mg_chelatase PF01078.21 PRP75973.1 - 0.021 14.2 1.9 2.7 7.3 0.0 3.4 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 PRP75973.1 - 0.022 15.0 0.2 19 5.5 0.0 4.0 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 PRP75973.1 - 0.066 13.0 0.1 19 4.9 0.0 3.6 4 0 0 4 4 3 0 IstB-like ATP binding protein NACHT PF05729.12 PRP75973.1 - 0.099 12.5 0.2 63 3.4 0.0 3.8 3 0 0 3 3 3 0 NACHT domain DUF5082 PF16888.5 PRP75973.1 - 0.11 12.8 17.1 0.066 13.5 4.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Cytidylate_kin PF02224.18 PRP75973.1 - 0.13 12.0 1.6 33 4.1 0.1 4.0 5 0 0 5 5 4 0 Cytidylate kinase SesA PF17107.5 PRP75973.1 - 1.6 8.9 13.8 0.057 13.6 2.4 4.0 3 0 0 3 3 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RNase_H2-Ydr279 PF09468.10 PRP75973.1 - 2 8.6 7.0 9.3 6.4 0.8 3.7 4 0 0 4 4 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain ERM PF00769.19 PRP75973.1 - 4.2 7.1 33.3 0.082 12.7 7.3 3.9 4 0 0 4 4 3 0 Ezrin/radixin/moesin family LAG1-DNAbind PF09271.11 PRP75974.1 - 0.037 14.7 0.0 0.058 14.0 0.0 1.4 1 0 0 1 1 1 0 LAG1, DNA binding Whib PF02467.16 PRP75974.1 - 0.049 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Transcription factor WhiB VWA PF00092.28 PRP75975.1 - 3.4e-16 60.0 0.0 1.2e-15 58.3 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP75975.1 - 6.4e-13 49.3 0.2 1.5e-12 48.1 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PRP75975.1 - 5e-11 42.8 0.0 8.7e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec23_trunk PF04811.15 PRP75975.1 - 0.087 12.4 0.2 0.66 9.5 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain DUF1682 PF07946.14 PRP75977.1 - 0.0022 17.3 11.1 0.0022 17.3 11.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) zf-CCCH_4 PF18044.1 PRP75977.1 - 0.0031 17.3 1.0 0.0062 16.3 1.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PRP75977.1 - 0.23 11.6 1.7 0.43 10.7 1.7 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 PRP75977.1 - 0.42 10.6 1.7 0.79 9.7 1.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDC45 PF02724.14 PRP75977.1 - 1.8 6.7 12.7 3.2 5.9 12.7 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.13 PRP75977.1 - 2.3 7.7 26.9 0.21 11.2 21.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) Borrelia_P83 PF05262.11 PRP75977.1 - 3.9 5.8 18.4 7.5 4.9 18.4 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein ALMT PF11744.8 PRP75977.1 - 9.7 4.9 7.8 19 4.0 7.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter HTH_28 PF13518.6 PRP75979.1 - 2.3e-06 27.6 0.3 0.0026 17.9 0.1 2.6 2 1 1 3 3 3 2 Helix-turn-helix domain Homeodomain PF00046.29 PRP75979.1 - 1.1e-05 25.1 2.9 0.0032 17.3 1.2 2.5 2 0 0 2 2 2 2 Homeodomain HTH_Tnp_1 PF01527.20 PRP75979.1 - 0.00014 22.1 3.8 0.19 12.1 0.2 2.7 2 1 1 3 3 3 2 Transposase HTH_26 PF13443.6 PRP75979.1 - 0.00016 22.0 0.3 0.11 12.9 0.1 2.3 2 0 0 2 2 2 2 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.6 PRP75979.1 - 0.0047 16.7 0.9 0.21 11.4 0.1 2.8 2 1 1 3 3 3 1 Homeodomain-like domain YdaS_antitoxin PF15943.5 PRP75979.1 - 0.0087 15.9 0.0 1.5 8.7 0.0 2.8 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_29 PF13551.6 PRP75979.1 - 0.01 15.8 0.1 5.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Homeobox_KN PF05920.11 PRP75979.1 - 0.028 14.3 2.4 0.17 11.8 0.5 2.7 3 0 0 3 3 3 0 Homeobox KN domain Arc PF03869.14 PRP75979.1 - 0.038 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Arc-like DNA binding domain CENP-B_N PF04218.13 PRP75979.1 - 0.052 13.2 0.4 7.5 6.3 0.0 2.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain DUF746 PF05344.11 PRP75979.1 - 0.054 13.3 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) HTH_19 PF12844.7 PRP75979.1 - 0.08 13.0 0.0 1.5 8.9 0.0 2.6 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_36 PF13730.6 PRP75979.1 - 0.12 12.4 0.1 12 6.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain CDC45 PF02724.14 PRP75979.1 - 0.24 9.6 6.3 0.3 9.3 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 PRP75979.1 - 0.56 10.6 4.5 1.5 9.3 4.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Acetyltransf_1 PF00583.25 PRP75981.1 - 9.4e-16 58.1 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP75981.1 - 3.6e-12 46.3 0.0 6.2e-12 45.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP75981.1 - 1.2e-09 38.5 0.0 1.6e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP75981.1 - 7.9e-06 26.6 0.0 1e-05 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP75981.1 - 0.0018 18.2 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 PRP75981.1 - 0.003 17.6 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 PRP75981.1 - 0.0034 17.5 0.0 0.0077 16.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PRP75981.1 - 0.0077 15.9 0.1 0.0092 15.7 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 PRP75981.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase GNAT_acetyltran PF12746.7 PRP75981.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 1 0 1 1 1 0 GNAT acetyltransferase bMG10 PF17973.1 PRP75982.1 - 8.6e-31 106.8 0.1 4e-30 104.7 0.1 2.3 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain MG2 PF01835.19 PRP75982.1 - 2.1e-18 66.5 2.4 5.6e-16 58.8 0.0 4.9 6 0 0 6 6 6 1 MG2 domain A2M PF00207.22 PRP75982.1 - 7.3e-18 64.2 0.0 1.9e-16 59.7 0.0 3.2 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 PRP75982.1 - 3.8e-16 59.7 0.6 3.8e-16 59.7 0.6 3.9 3 1 0 3 3 3 1 Alpha-2-macroglobulin bait region domain Ank_2 PF12796.7 PRP75982.1 - 2.6e-15 56.8 0.1 1e-09 38.9 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP75982.1 - 1.9e-12 47.4 0.1 0.00054 20.5 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP75982.1 - 2.5e-07 30.8 0.0 1.3 9.6 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Big_5 PF13205.6 PRP75982.1 - 6e-07 30.1 4.5 0.31 11.7 0.3 5.7 4 1 0 4 4 4 2 Bacterial Ig-like domain TED_complement PF07678.14 PRP75982.1 - 0.0003 19.9 0.0 0.0023 17.0 0.0 2.0 2 0 0 2 2 2 1 A-macroglobulin TED domain DUF11 PF01345.18 PRP75982.1 - 0.00043 20.5 0.1 0.013 15.8 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF11 Ank_5 PF13857.6 PRP75982.1 - 0.0055 17.0 0.0 34 4.9 0.0 4.2 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Big_1 PF02369.16 PRP75982.1 - 0.21 11.6 10.3 15 5.7 0.0 6.5 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 PRP75982.1 - 2.7 8.3 10.9 3.2 8.1 0.2 4.3 5 0 0 5 5 5 0 Invasin, domain 3 Ank_4 PF13637.6 PRP75983.1 - 7.2e-07 29.6 0.0 1.4e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP75983.1 - 5.1e-05 23.8 0.0 0.00012 22.6 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP75983.1 - 0.0038 17.5 0.0 3.2 8.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP75983.1 - 0.032 14.7 0.0 8.9 7.2 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 PRP75983.1 - 0.037 14.5 0.2 15 6.2 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat PLDc_2 PF13091.6 PRP75984.1 - 9.4e-17 61.1 0.0 2.1e-10 40.6 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 PRP75984.1 - 1.4e-16 59.9 3.5 1.7e-09 37.4 0.1 3.2 3 0 0 3 3 3 2 Phospholipase D Active site motif PH PF00169.29 PRP75984.1 - 1.4e-05 25.6 0.0 4.2e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 PH domain Peroxidase_2 PF01328.17 PRP75985.1 - 4.5e-44 151.2 0.0 5.7e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 His_Phos_2 PF00328.22 PRP75986.1 - 1.8e-27 96.7 0.1 8.4e-27 94.5 0.1 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SfLAP PF11139.8 PRP75987.1 - 0.00049 19.6 0.6 0.00049 19.6 0.6 2.0 2 0 0 2 2 2 1 Sap, sulfolipid-1-addressing protein DNA_pol_A_exo1 PF01612.20 PRP75988.1 - 2.1e-26 92.7 0.2 4.1e-26 91.8 0.2 1.5 1 0 0 1 1 1 1 3'-5' exonuclease AAA_16 PF13191.6 PRP75988.1 - 9e-08 32.7 0.0 2.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PRP75988.1 - 2.1e-05 24.8 0.0 6.6e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PRP75988.1 - 6.9e-05 22.9 0.0 0.00022 21.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PRP75988.1 - 8.7e-05 23.1 0.0 0.00025 21.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 PRP75988.1 - 0.00013 21.6 0.1 0.00032 20.4 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 PRP75988.1 - 0.00055 20.4 0.0 0.0028 18.1 0.0 2.3 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 PRP75988.1 - 0.00063 19.7 0.0 0.0076 16.2 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 PRP75988.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP75988.1 - 0.0009 18.6 0.0 0.0027 17.0 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin TniB PF05621.11 PRP75988.1 - 0.0012 18.3 0.1 0.0037 16.7 0.0 1.8 2 0 0 2 2 1 1 Bacterial TniB protein AAA_33 PF13671.6 PRP75988.1 - 0.0016 18.6 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 PRP75988.1 - 0.0017 17.4 0.0 0.0033 16.4 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 PRP75988.1 - 0.0025 18.0 0.0 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 PRP75988.1 - 0.0028 17.4 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PRP75988.1 - 0.0034 17.1 0.1 0.013 15.3 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 PRP75988.1 - 0.0037 17.2 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 PRP75988.1 - 0.0039 16.7 0.0 0.0096 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 PRP75988.1 - 0.0051 17.2 0.0 0.026 14.9 0.0 2.2 2 0 0 2 2 1 1 RNA helicase Rad17 PF03215.15 PRP75988.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain T2SSE PF00437.20 PRP75988.1 - 0.0077 15.3 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein PcfJ PF14284.6 PRP75988.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 PcfJ-like protein Mg_chelatase PF01078.21 PRP75988.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 PRP75988.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 PRP75988.1 - 0.012 15.9 0.0 0.046 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PRP75988.1 - 0.017 15.1 0.0 0.069 13.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 PRP75988.1 - 0.021 15.1 0.1 0.07 13.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 PRP75988.1 - 0.022 15.3 0.1 0.12 12.9 0.0 2.4 2 0 0 2 2 1 0 ABC transporter TsaE PF02367.17 PRP75988.1 - 0.025 14.6 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 PRP75988.1 - 0.028 13.4 0.0 0.069 12.1 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATPase PF06745.13 PRP75988.1 - 0.029 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 PRP75988.1 - 0.032 14.2 0.1 0.08 12.8 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 PRP75988.1 - 0.037 13.7 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KTI12 PF08433.10 PRP75988.1 - 0.041 13.3 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Terminase_6 PF03237.15 PRP75988.1 - 0.043 13.5 0.0 0.5 10.0 0.0 2.4 1 1 1 2 2 2 0 Terminase-like family IstB_IS21 PF01695.17 PRP75988.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 PRP75988.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.6 PRP75988.1 - 0.07 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 PRP75988.1 - 0.071 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_11 PF13086.6 PRP75988.1 - 0.072 12.9 1.8 0.19 11.5 0.0 2.4 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 PRP75988.1 - 0.076 12.8 0.1 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 PRP75988.1 - 0.096 12.8 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 PRP75988.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DHO_dh PF01180.21 PRP75989.1 - 2.5e-32 112.3 0.0 1e-31 110.2 0.0 2.0 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 PRP75989.1 - 1e-31 109.0 0.2 1e-31 109.0 0.2 2.6 2 1 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 PRP75989.1 - 2.1e-22 79.0 13.2 2.1e-22 79.0 13.2 3.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 PRP75989.1 - 3.2e-14 52.8 0.0 5.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.6 PRP75989.1 - 2.8e-07 30.5 21.6 1.7e-05 24.8 8.4 2.8 2 0 0 2 2 2 2 4Fe-4S dicluster domain Dus PF01207.17 PRP75989.1 - 3.4e-06 26.4 0.0 7.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Fer4_2 PF12797.7 PRP75989.1 - 1.2e-05 25.1 29.4 0.012 15.6 2.5 4.6 4 0 0 4 4 4 3 4Fe-4S binding domain Fer4_7 PF12838.7 PRP75989.1 - 1.4e-05 25.5 9.0 1.4e-05 25.5 9.0 3.4 3 0 0 3 3 2 2 4Fe-4S dicluster domain Pyr_redox PF00070.27 PRP75989.1 - 0.00012 22.5 0.0 0.057 14.0 0.0 3.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 PRP75989.1 - 0.00016 21.6 32.0 0.00016 21.6 1.5 4.4 4 1 1 5 5 4 3 4Fe-4S binding domain NAD_binding_8 PF13450.6 PRP75989.1 - 0.00077 19.7 0.0 0.003 17.7 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PRP75989.1 - 0.0011 18.3 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.6 PRP75989.1 - 0.0013 18.8 11.6 0.0013 18.8 11.6 2.9 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4 PF00037.27 PRP75989.1 - 0.0035 17.1 14.8 0.0064 16.3 4.1 4.7 5 0 0 5 5 5 2 4Fe-4S binding domain Fer4_17 PF13534.6 PRP75989.1 - 0.051 14.1 18.9 0.2 12.2 0.3 4.0 3 1 1 4 4 3 0 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 PRP75989.1 - 0.054 12.8 0.0 3.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 PRP75989.1 - 0.064 13.3 0.0 11 6.1 0.0 3.1 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.13 PRP75989.1 - 0.14 12.1 0.0 5.3 7.0 0.0 3.1 4 0 0 4 4 4 0 Glycosyl transferase WecB/TagA/CpsF family Fer4_8 PF13183.6 PRP75989.1 - 0.27 11.7 19.8 0.09 13.2 0.6 3.9 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 PRP75989.1 - 4.6 8.1 10.1 9.7 7.0 0.3 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_18 PF13746.6 PRP75989.1 - 8.8 6.6 16.5 11 6.2 0.1 3.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain zf-C3HC4_3 PF13920.6 PRP75991.1 - 5e-05 23.1 1.3 0.00072 19.4 0.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP75991.1 - 0.025 14.5 4.8 0.081 12.8 4.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP75991.1 - 0.043 13.8 1.5 0.043 13.8 1.5 2.5 3 1 1 4 4 4 0 zinc-RING finger domain zf-RING_4 PF14570.6 PRP75991.1 - 0.049 13.4 1.6 0.42 10.4 0.5 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 PRP75991.1 - 0.87 10.0 6.2 1.5 9.2 4.5 2.4 2 1 0 2 2 2 0 Ring finger domain HNH_2 PF13391.6 PRP75993.1 - 4.4e-06 26.7 0.0 0.084 13.0 0.0 2.6 2 0 0 2 2 2 2 HNH endonuclease RBP_receptor PF14752.6 PRP75995.1 - 4.2e-12 45.4 18.5 7.4e-12 44.6 10.3 2.6 2 1 1 3 3 3 2 Retinol binding protein receptor Pox_A14 PF05767.12 PRP75995.1 - 0.1 12.8 0.1 0.1 12.8 0.1 3.4 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 PetL PF05115.14 PRP75995.1 - 0.31 11.0 4.2 2.3 8.3 0.9 3.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) GDPD PF03009.17 PRP75996.1 - 3.7e-20 72.7 0.2 1.5e-14 54.4 0.2 2.7 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Sod_Cu PF00080.20 PRP75997.1 - 5.9e-30 104.3 0.3 8.3e-30 103.8 0.3 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PH PF00169.29 PRP75999.1 - 5.8e-05 23.6 1.0 9.6e-05 22.9 1.0 1.4 1 0 0 1 1 1 1 PH domain ydhR PF08803.11 PRP75999.1 - 0.014 15.3 0.2 0.086 12.8 0.0 2.1 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR Sortase PF04203.13 PRP75999.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Sortase domain DUF4336 PF14234.6 PRP76000.1 - 1.6e-07 30.9 0.0 0.00084 18.6 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Cyclin PF08613.11 PRP76001.1 - 0.044 14.2 0.4 0.059 13.7 0.4 1.2 1 0 0 1 1 1 0 Cyclin HATPase_c PF02518.26 PRP76003.1 - 1.1e-28 99.9 0.1 3.3e-28 98.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP76003.1 - 2e-19 69.8 1.7 5.7e-19 68.3 0.8 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 PRP76003.1 - 2.9e-14 52.9 0.1 9.6e-14 51.2 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CCDC71L PF15374.6 PRP76003.1 - 0.084 12.1 1.7 1.2 8.3 0.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L TSC22 PF01166.18 PRP76004.1 - 0.055 13.8 3.9 0.076 13.3 0.8 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 PRP76004.1 - 0.58 10.8 6.2 2 9.1 6.2 2.0 1 1 0 1 1 1 0 Initiation control protein YabA IPK PF03770.16 PRP76005.1 - 1.8e-41 142.2 0.1 2.9e-41 141.5 0.1 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Phosphodiest PF01663.22 PRP76006.1 - 2.7e-14 53.6 0.5 1.6e-13 51.0 0.5 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PRP76006.1 - 0.0068 15.8 0.1 0.065 12.6 0.0 2.1 2 0 0 2 2 2 1 Sulfatase Neurokinin_B PF03823.14 PRP76007.1 - 0.017 15.2 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 Neurokinin B Asp4 PF16996.5 PRP76007.1 - 0.04 13.7 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 COX2-transmemb PF09125.10 PRP76007.1 - 0.085 12.7 0.6 0.25 11.2 0.6 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane Sigma_reg_N PF13800.6 PRP76007.1 - 8 6.8 11.8 11 6.4 0.1 4.1 4 0 0 4 4 4 0 Sigma factor regulator N-terminal DUF1768 PF08719.11 PRP76010.1 - 3.1e-54 183.5 0.5 5.4e-54 182.8 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Aminotran_5 PF00266.19 PRP76011.1 - 8.6e-66 222.4 0.0 1.7e-64 218.1 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PRP76011.1 - 0.00028 20.3 0.0 0.00071 18.9 0.0 1.6 1 1 1 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 PRP76011.1 - 0.029 12.9 0.0 0.04 12.4 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 PRP76011.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 PRP76011.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.25 PRP76012.1 - 3.5e-63 213.4 0.0 5.6e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76012.1 - 1.1e-36 126.5 0.0 1.9e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.19 PRP76012.1 - 2.1e-31 109.5 0.0 5.4e-31 108.1 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain Kinase-like PF14531.6 PRP76012.1 - 1.1e-07 31.4 0.0 2.8e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RasGEF_N PF00618.20 PRP76012.1 - 5.6e-05 23.3 0.1 0.00014 22.0 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif APH PF01636.23 PRP76012.1 - 0.00011 22.2 0.0 0.031 14.2 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP76012.1 - 0.00019 20.4 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP76012.1 - 0.00028 20.3 0.1 0.0007 19.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP76012.1 - 0.052 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.25 PRP76013.1 - 5.8e-25 87.9 0.0 9.5e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP76013.1 - 4.1e-20 72.3 0.1 7.7e-20 71.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP76013.1 - 2.9e-09 37.1 0.0 5.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP76013.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP76013.1 - 0.0066 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PRP76013.1 - 0.014 14.8 0.0 0.049 13.0 0.0 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Mak10 PF04112.13 PRP76015.1 - 1.6e-31 109.1 0.0 6.9e-24 84.2 0.0 2.6 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF600 PF04634.12 PRP76016.1 - 0.043 13.9 0.5 9.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF600 VD10_N PF08476.10 PRP76016.1 - 0.12 12.0 0.1 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Viral D10 N-terminal LuxT_C PF18285.1 PRP76016.1 - 0.13 12.8 0.0 7.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain Xpo1 PF08389.12 PRP76017.1 - 6.6e-23 81.4 3.4 9.4e-23 80.9 0.1 3.1 3 1 1 4 4 4 1 Exportin 1-like protein CCDC117 PF15810.5 PRP76017.1 - 0.1 12.9 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 Guanylate_cyc PF00211.20 PRP76018.1 - 3.3e-30 105.1 0.1 6.9e-30 104.0 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AMP-binding PF00501.28 PRP76018.1 - 2.3e-29 102.2 0.0 4.7e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 PRP76018.1 - 1.8e-18 66.7 0.0 3.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 PRP76018.1 - 4.1e-10 39.9 0.0 1.1e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 PRP76018.1 - 0.003 17.1 0.0 0.0064 16.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4358 PF14270.6 PRP76018.1 - 0.099 12.9 0.4 7.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) Kinesin PF00225.23 PRP76019.1 - 8.5e-66 222.1 0.5 1.2e-65 221.6 0.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PRP76019.1 - 6e-15 55.5 0.0 1.3e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 PRP76019.1 - 1.1 9.4 3.5 2.2 8.3 0.5 2.4 1 1 0 2 2 2 0 Helicase HerA, central domain DUF4028 PF13220.6 PRP76020.1 - 0.082 12.7 0.1 0.37 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) PP28 PF10252.9 PRP76020.1 - 0.087 13.3 0.4 0.12 12.8 0.4 1.2 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 CLU PF13236.6 PRP76021.1 - 7.5e-48 163.3 0.0 1.5e-47 162.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP76021.1 - 1.1e-10 41.8 0.0 2e-09 37.7 0.0 2.5 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 NatB_MDM20 PF09797.9 PRP76022.1 - 2.9e-65 220.7 2.0 2.9e-65 220.7 2.0 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 PRP76022.1 - 4.5e-07 30.2 0.5 1.3 10.0 0.0 5.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP76022.1 - 6.4e-06 25.9 0.3 0.033 14.3 0.1 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP76022.1 - 1.6e-05 24.6 0.0 0.32 10.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP76022.1 - 2.2e-05 24.1 0.2 9.1 6.6 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP76022.1 - 3.1e-05 24.2 0.3 0.05 13.9 0.0 4.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP76022.1 - 3.4e-05 24.2 1.5 1.6 9.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.20 PRP76022.1 - 0.0017 18.5 0.1 7.1 7.1 0.0 4.5 4 0 0 4 4 4 1 PPR repeat TPR_19 PF14559.6 PRP76022.1 - 0.0025 18.3 0.2 1.5 9.4 0.0 3.8 3 1 0 4 4 4 1 Tetratricopeptide repeat IL11 PF07400.11 PRP76022.1 - 0.0054 16.4 5.2 0.029 14.0 0.7 2.8 2 0 0 2 2 2 1 Interleukin 11 TPR_8 PF13181.6 PRP76022.1 - 0.0083 16.3 1.7 10 6.7 0.1 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP76022.1 - 0.014 16.1 0.0 10 6.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP76022.1 - 0.023 14.5 1.7 1.5 8.8 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 PRP76022.1 - 0.034 13.9 0.3 0.15 11.7 0.0 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat-like domain UPF0449 PF15136.6 PRP76022.1 - 0.078 13.4 4.1 1.5 9.3 0.1 3.3 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 TPR_11 PF13414.6 PRP76022.1 - 0.11 12.2 0.2 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 TPR repeat ZIP4_domain PF18292.1 PRP76022.1 - 3.9 7.4 6.1 3.3 7.6 1.2 2.9 3 0 0 3 3 3 0 Zinc transporter ZIP4 domain HAGH_C PF16123.5 PRP76023.1 - 2.8e-26 91.8 0.0 7.2e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 PRP76023.1 - 2.4e-13 50.5 2.7 5e-13 49.5 2.7 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PRP76023.1 - 0.00014 21.5 0.9 0.00094 18.8 0.9 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PRP76023.1 - 0.019 14.8 0.4 0.05 13.5 0.4 1.7 1 1 1 2 2 2 0 Beta-lactamase superfamily domain DUF3294 PF07957.11 PRP76025.1 - 0.0015 18.4 7.3 0.0021 17.8 7.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3294) ADIP PF11559.8 PRP76025.1 - 0.25 11.4 13.4 0.034 14.2 8.1 1.9 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SpecificRecomb PF10136.9 PRP76025.1 - 1.8 6.8 6.9 2.5 6.3 6.9 1.2 1 0 0 1 1 1 0 Site-specific recombinase TSNAXIP1_N PF15739.5 PRP76025.1 - 2 8.8 11.3 17 5.9 10.1 2.5 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus LMBR1 PF04791.16 PRP76025.1 - 2.8 6.8 4.8 3.5 6.4 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GLE1 PF07817.13 PRP76025.1 - 5.3 6.2 7.7 7.1 5.7 0.8 2.1 1 1 1 2 2 2 0 GLE1-like protein Homeodomain PF00046.29 PRP76026.1 - 1.2e-16 60.3 3.1 2e-16 59.5 3.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP76026.1 - 1.6e-05 24.7 1.2 3e-05 23.8 1.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain Pkinase PF00069.25 PRP76028.1 - 9e-64 215.4 0.0 1.1e-63 215.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76028.1 - 1.4e-38 132.7 0.0 1.7e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP76028.1 - 2.6e-08 33.5 0.0 3.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP76028.1 - 3.1e-06 26.7 0.2 5.1e-06 26.0 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP76028.1 - 5.5e-06 26.1 0.0 8.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 PRP76028.1 - 2.5e-05 23.2 0.0 4.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PRP76028.1 - 2.7e-05 24.2 0.0 0.00075 19.5 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP76028.1 - 0.00079 18.5 0.2 0.0011 17.9 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Arrestin_N PF00339.29 PRP76029.1 - 5.9e-12 45.9 0.1 3.9e-11 43.2 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PRP76029.1 - 3.6e-09 37.2 0.8 9.9e-09 35.8 0.8 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Zn_clus PF00172.18 PRP76029.1 - 2.1e-06 27.7 15.1 4.1e-06 26.8 15.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rgp1 PF08737.10 PRP76029.1 - 0.00085 18.6 2.5 0.068 12.3 0.2 3.1 2 1 1 3 3 3 2 Rgp1 DUF3458_C PF17432.2 PRP76029.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3458_C) ARM repeats Pkinase PF00069.25 PRP76030.1 - 3.5e-71 239.7 0.0 4.7e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76030.1 - 5.8e-41 140.5 0.0 7.7e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP76030.1 - 1.2e-06 28.1 0.1 9.2e-06 25.2 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PRP76030.1 - 2.2e-05 24.5 0.0 9.9e-05 22.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP76030.1 - 6.1e-05 22.7 0.1 9.9e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 PRP76030.1 - 6.7e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP76030.1 - 0.00013 21.4 0.2 0.00022 20.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L36e PF01158.18 PRP76030.1 - 0.037 14.3 0.1 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L36e Haspin_kinase PF12330.8 PRP76030.1 - 0.093 11.7 0.2 0.13 11.2 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 PRP76030.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 PRP76031.1 - 3.1e-43 148.0 0.0 3.6e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76031.1 - 5.1e-19 68.6 0.0 6.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP76031.1 - 1.4e-06 28.5 0.0 9.2e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP76031.1 - 5.7e-05 22.6 0.5 0.00014 21.3 0.1 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP76031.1 - 7.6e-05 22.2 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.20 PRP76031.1 - 0.00036 20.2 0.1 0.00065 19.3 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PRP76031.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase TMEM72 PF16054.5 PRP76032.1 - 0.082 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 72 DUF2418 PF10332.9 PRP76032.1 - 0.1 13.1 0.2 0.28 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) cobW PF02492.19 PRP76034.1 - 2e-26 92.7 0.7 2.6e-26 92.3 0.7 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PRP76034.1 - 3e-21 75.1 0.0 1.1e-20 73.4 0.0 2.0 3 0 0 3 3 3 1 Cobalamin synthesis protein cobW C-terminal domain AAA_15 PF13175.6 PRP76034.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 PRP76034.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain GP67 PF17634.2 PRP76034.1 - 8.8 6.8 14.5 23 5.5 14.5 1.6 1 0 0 1 1 1 0 Gene product 67 DUF4156 PF13698.6 PRP76036.1 - 0.017 15.5 0.0 9.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4156) SET PF00856.28 PRP76038.1 - 2.2e-12 47.7 0.4 1.9e-10 41.4 0.2 2.6 2 1 0 2 2 2 1 SET domain Peptidase_C1 PF00112.23 PRP76039.1 - 1.2e-46 159.6 1.1 2.6e-46 158.4 1.1 1.6 1 0 0 1 1 1 1 Papain family cysteine protease PAN_4 PF14295.6 PRP76039.1 - 4.6e-13 48.9 21.6 2.2e-08 33.9 6.7 3.9 4 0 0 4 4 4 2 PAN domain PAN_1 PF00024.26 PRP76039.1 - 1.2e-08 34.8 17.8 8.9e-06 25.6 0.7 3.3 3 0 0 3 3 3 2 PAN domain Inhibitor_I29 PF08246.12 PRP76039.1 - 4.9e-08 33.3 2.2 7.5e-08 32.7 2.2 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP76039.1 - 6e-05 22.0 2.3 0.0022 16.8 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family PAN_2 PF08276.11 PRP76039.1 - 0.0012 18.9 0.9 0.0012 18.9 0.9 3.7 4 0 0 4 4 4 2 PAN-like domain Carb_bind PF10645.9 PRP76039.1 - 0.0018 18.5 9.0 0.0018 18.5 9.0 5.2 4 3 1 5 5 5 1 Carbohydrate binding PAN_3 PF08277.12 PRP76039.1 - 0.19 11.6 10.7 2 8.3 1.4 3.0 2 0 0 2 2 2 0 PAN-like domain Period_C PF12114.8 PRP76039.1 - 0.67 9.5 6.7 9.6 5.7 0.2 2.4 1 1 0 2 2 2 0 Period protein 2/3C-terminal region Glyco_hydro_38N PF01074.22 PRP76040.1 - 5.1e-85 285.3 1.1 9.2e-85 284.5 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP76040.1 - 4.1e-63 213.3 0.0 6.3e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP76040.1 - 2.9e-30 104.3 0.1 7.1e-30 103.0 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PRP76040.1 - 1.3e-12 47.6 0.0 8.6e-12 45.0 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 PRP76040.1 - 0.00093 18.5 0.0 0.0025 17.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 GATase PF00117.28 PRP76041.1 - 2.1e-15 57.0 0.0 2.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PRP76041.1 - 2.6e-05 24.1 0.4 0.00075 19.3 0.4 2.7 1 1 0 1 1 1 1 Peptidase C26 HTS PF04204.16 PRP76041.1 - 0.031 13.2 0.0 0.05 12.5 0.0 1.5 1 1 0 1 1 1 0 Homoserine O-succinyltransferase GATase_3 PF07685.14 PRP76041.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain SNF2_N PF00176.23 PRP76042.1 - 2.2e-59 200.9 1.8 2.6e-58 197.4 0.4 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 PRP76042.1 - 1.6e-35 122.4 20.3 5e-35 120.8 20.3 1.9 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.31 PRP76042.1 - 1.4e-20 73.7 0.1 3.3e-19 69.3 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 PRP76042.1 - 1.2e-05 24.6 0.1 1.2e-05 24.6 0.1 2.3 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 X8 PF07983.13 PRP76043.1 - 6.3e-30 103.7 20.4 4.7e-11 43.2 1.9 3.8 4 0 0 4 4 4 3 X8 domain Glyco_hydro_17 PF00332.18 PRP76043.1 - 2.1e-09 37.4 0.3 9.1e-07 28.8 0.0 2.8 2 1 0 3 3 3 2 Glycosyl hydrolases family 17 RabGAP-TBC PF00566.18 PRP76044.1 - 5.7e-49 166.7 2.0 1.7e-48 165.2 2.0 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MCM_lid PF17855.1 PRP76044.1 - 0.04 14.3 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 MCM AAA-lid domain CodY PF06018.14 PRP76044.1 - 0.21 11.1 2.3 3.3 7.2 0.6 2.4 2 0 0 2 2 2 0 CodY GAF-like domain ABC_tran PF00005.27 PRP76045.1 - 2.3e-27 96.2 0.2 6.6e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 PRP76045.1 - 0.00067 19.1 1.0 0.0053 16.2 1.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PRP76045.1 - 0.0016 18.3 0.4 0.035 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 PRP76045.1 - 0.0076 16.5 0.1 0.24 11.7 0.1 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 PRP76045.1 - 0.026 14.4 0.1 0.069 13.0 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 PRP76045.1 - 0.12 12.1 0.2 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 PRP76045.1 - 0.12 12.6 0.3 0.12 12.6 0.3 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP76045.1 - 0.2 11.4 0.2 0.41 10.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP76045.1 - 0.21 12.1 2.7 1.2 9.6 0.5 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PRP76045.1 - 0.22 11.8 0.7 0.79 10.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 PRP76046.1 - 2.2e-38 132.1 51.6 1.4e-35 122.9 52.5 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 PRP76046.1 - 1.9e-07 29.9 16.3 3.7e-07 29.0 14.0 2.1 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Protamine_P2 PF00841.19 PRP76046.1 - 0.048 14.1 0.6 0.14 12.6 0.6 1.7 1 0 0 1 1 1 0 Sperm histone P2 Peptidase_C78 PF07910.13 PRP76046.1 - 0.21 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C78 WLM PF08325.10 PRP76047.1 - 1.7e-43 148.9 0.5 1.7e-43 148.9 0.5 1.9 2 0 0 2 2 2 1 WLM domain TAFII28 PF04719.14 PRP76047.1 - 1.2e-30 105.4 0.1 2.5e-30 104.4 0.1 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF45 PF01863.17 PRP76047.1 - 0.0011 19.1 0.3 0.0011 19.1 0.3 2.3 3 0 0 3 3 3 1 Protein of unknown function DUF45 ubiquitin PF00240.23 PRP76047.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family APG5 PF04106.12 PRP76048.1 - 6.4e-51 173.1 0.1 2.2e-50 171.4 0.0 1.9 2 1 0 2 2 2 1 Autophagy protein Apg5 FLYWCH PF04500.16 PRP76049.1 - 0.00039 20.5 2.4 0.0012 18.9 2.4 1.8 1 0 0 1 1 1 1 FLYWCH zinc finger domain WRKY PF03106.15 PRP76049.1 - 0.0017 18.5 3.2 0.0051 17.0 3.2 1.9 1 0 0 1 1 1 1 WRKY DNA -binding domain FAR1 PF03101.15 PRP76049.1 - 0.0056 17.3 0.7 0.014 16.0 0.7 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain MULE PF10551.9 PRP76049.1 - 0.013 15.9 0.0 0.043 14.2 0.0 2.0 1 1 0 1 1 1 0 MULE transposase domain Zn_ribbon_recom PF13408.6 PRP76049.1 - 0.76 10.3 3.1 2 9.0 3.1 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain tRNA_U5-meth_tr PF05958.11 PRP76050.1 - 2.9e-18 66.0 0.0 1e-17 64.2 0.0 2.0 3 0 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 PRP76050.1 - 1.9e-10 40.7 0.0 3.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP76050.1 - 1e-08 35.8 0.0 2.5e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP76050.1 - 7.3e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 PRP76050.1 - 1.2e-07 31.4 0.0 2.1e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 PRP76050.1 - 3.3e-06 26.9 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 PRP76050.1 - 3.3e-06 26.7 0.1 5.8e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 PRP76050.1 - 1.5e-05 25.5 0.0 3.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PRP76050.1 - 1.6e-05 24.4 0.1 2.9e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 PRP76050.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AviRa PF11599.8 PRP76050.1 - 0.0021 17.5 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa NodS PF05401.11 PRP76050.1 - 0.0035 17.0 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 PRP76050.1 - 0.021 15.5 0.0 0.052 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 PRP76050.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PRP76050.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1140 PF06600.11 PRP76051.1 - 0.12 12.8 2.3 0.2 12.1 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1140) TauE PF01925.19 PRP76052.1 - 4.1e-30 105.2 29.5 3.6e-26 92.2 28.3 2.5 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE Paf67 PF10255.9 PRP76053.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Ras PF00071.22 PRP76054.1 - 2e-52 177.0 1.3 5.9e-52 175.5 1.3 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP76054.1 - 9.2e-19 67.8 0.9 1.5e-17 63.9 0.9 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP76054.1 - 2.3e-08 33.7 0.2 2.9e-07 30.1 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP76054.1 - 0.0002 21.3 0.7 0.67 9.8 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 PRP76054.1 - 0.0017 17.9 0.7 0.17 11.4 0.0 2.8 1 1 1 3 3 3 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 PRP76054.1 - 0.0037 17.3 0.0 0.0087 16.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF465 PF04325.13 PRP76054.1 - 0.032 14.3 0.4 0.077 13.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) NB-ARC PF00931.22 PRP76054.1 - 0.06 12.5 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 PRP76054.1 - 0.077 13.3 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PRP76054.1 - 0.097 12.4 2.5 2.6 7.7 0.0 3.1 2 1 0 3 3 3 0 AAA domain RhoGAP PF00620.27 PRP76055.1 - 4.3e-41 140.3 0.1 7.1e-41 139.5 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 PRP76055.1 - 0.00059 19.1 0.1 0.0015 17.8 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) Aminotran_1_2 PF00155.21 PRP76056.1 - 8.3e-52 176.6 0.0 9.9e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PRP76056.1 - 3.6e-05 23.2 0.0 5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 PRP76056.1 - 0.087 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PRP76056.1 - 0.19 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V adh_short PF00106.25 PRP76057.1 - 2.5e-41 141.3 0.0 3.1e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP76057.1 - 1.7e-29 103.1 0.0 2.2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP76057.1 - 6.1e-06 26.3 0.1 9.6e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP76057.1 - 0.0028 17.1 0.2 0.0056 16.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP76057.1 - 0.0029 17.0 0.1 0.0044 16.5 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 PRP76057.1 - 0.0035 16.7 0.0 0.01 15.3 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) UPF0223 PF05256.12 PRP76057.1 - 0.15 12.5 0.1 4.8 7.6 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0223) DOMON PF03351.17 PRP76058.1 - 1.1e-140 461.8 31.9 2.7e-25 89.0 0.5 6.4 6 0 0 6 6 6 6 DOMON domain CDH-cyt PF16010.5 PRP76058.1 - 6.3e-22 78.1 23.8 3.7e-05 23.5 2.4 5.7 5 0 0 5 5 5 4 Cytochrome domain of cellobiose dehydrogenase Ferric_reduct PF01794.19 PRP76058.1 - 7.4e-21 74.6 9.8 1.6e-20 73.4 9.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 PRP76058.1 - 4e-15 55.8 0.0 9.8e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 PRP76058.1 - 8.9e-15 55.1 0.0 2.6e-08 34.1 0.0 2.8 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 PRP76058.1 - 3e-08 34.3 0.0 8.2e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain F-box PF00646.33 PRP76059.1 - 2.3e-08 33.7 0.3 5.2e-08 32.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP76059.1 - 4.8e-07 29.6 1.5 6.9e-07 29.1 0.4 1.9 2 0 0 2 2 2 1 F-box-like SPRY PF00622.28 PRP76059.1 - 3.6e-06 27.1 0.0 6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain F-box_4 PF15966.5 PRP76059.1 - 2.1e-05 24.4 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 F-box Neuralized PF07177.12 PRP76059.1 - 0.00071 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Neuralized Ras PF00071.22 PRP76060.1 - 1.5e-52 177.5 0.0 2e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP76060.1 - 1.5e-17 63.9 0.0 2.7e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP76060.1 - 3.2e-10 39.8 0.0 4.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP76060.1 - 0.00038 20.1 0.0 0.00089 18.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP76060.1 - 0.0028 17.6 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 PRP76060.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain tRNA-synt_2 PF00152.20 PRP76061.1 - 5.2e-69 232.7 0.0 7.2e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PRP76061.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PRP76061.1 - 9.5e-06 25.3 0.0 0.15 11.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) START PF01852.19 PRP76062.1 - 7.7e-23 81.0 0.0 1.5e-22 80.0 0.0 1.5 1 1 0 1 1 1 1 START domain Glyco_transf_54 PF04666.13 PRP76062.1 - 1.5e-14 53.6 1.0 1.2e-05 24.3 0.1 4.0 2 2 1 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Got1 PF04178.12 PRP76062.1 - 2.1 8.8 9.0 2 8.8 4.0 2.3 2 0 0 2 2 2 0 Got1/Sft2-like family NIF PF03031.18 PRP76063.1 - 2.2e-25 89.3 0.7 3.3e-25 88.7 0.7 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 PRP76063.1 - 0.00099 18.8 0.0 0.0035 17.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Beta_helix PF13229.6 PRP76064.1 - 6.1e-11 42.4 18.9 0.00019 21.3 1.5 4.4 3 2 1 4 4 4 4 Right handed beta helix region BCAS3 PF12490.8 PRP76066.1 - 3.6e-14 52.9 3.3 1.5e-07 31.2 1.4 3.2 2 1 2 4 4 4 2 Breast carcinoma amplified sequence 3 WD40 PF00400.32 PRP76066.1 - 3.1e-05 24.7 0.1 0.0082 17.0 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat Lactonase PF10282.9 PRP76066.1 - 0.054 12.7 2.0 0.091 12.0 2.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Dmrt1 PF12374.8 PRP76068.1 - 5.5 7.5 11.8 0.81 10.2 0.1 3.4 2 1 0 2 2 2 0 Double-sex mab3 related transcription factor 1 PI3K_1B_p101 PF10486.9 PRP76068.1 - 6.8 4.3 11.1 1.9 6.2 8.0 1.5 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NAD_binding_5 PF07994.12 PRP76070.1 - 8e-141 469.1 0.0 8e-141 469.1 0.0 2.2 2 1 1 3 3 3 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 PRP76070.1 - 5.3e-48 161.8 3.4 3e-47 159.4 0.1 2.8 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase HAUS-augmin3 PF14932.6 PRP76070.1 - 3.6e-13 49.7 23.0 3.6e-13 49.7 23.0 3.7 3 2 0 3 3 3 1 HAUS augmin-like complex subunit 3 CLZ PF16526.5 PRP76070.1 - 0.00035 20.9 0.6 0.00035 20.9 0.6 4.4 4 1 0 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Dehalogenase PF13486.6 PRP76070.1 - 0.0028 17.1 0.0 0.0089 15.5 0.0 1.8 1 0 0 1 1 1 1 Reductive dehalogenase subunit DHquinase_II PF01220.19 PRP76070.1 - 5.3 6.7 7.1 0.57 9.8 1.4 2.3 2 0 0 2 2 2 0 Dehydroquinase class II DUF5542 PF17696.1 PRP76074.1 - 0.011 15.8 0.7 0.018 15.2 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Actin PF00022.19 PRP76075.1 - 5.8e-73 245.8 0.0 7.1e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Actin SASA PF03629.18 PRP76076.1 - 8.9e-15 54.9 0.0 1.7e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Ubiq_cyt_C_chap PF03981.12 PRP76076.1 - 0.13 12.3 1.7 0.28 11.3 1.7 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone CD34_antigen PF06365.12 PRP76077.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 CD34/Podocalyxin family Borrelia_P83 PF05262.11 PRP76078.1 - 0.028 12.9 42.1 0.049 12.1 42.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RSN1_7TM PF02714.15 PRP76079.1 - 4.2e-49 167.3 27.5 1e-47 162.7 26.5 2.8 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PRP76079.1 - 3.7e-29 101.5 1.4 3.7e-29 101.5 1.4 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PRP76079.1 - 2.8e-25 89.5 0.0 4.3e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter WD40 PF00400.32 PRP76080.1 - 6.4e-16 58.4 5.6 0.00052 20.8 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76080.1 - 2.7e-11 43.6 2.2 3.9e-05 23.9 0.4 3.9 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP76080.1 - 4.5e-06 25.6 1.4 3.8e-05 22.6 0.3 2.1 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PRP76080.1 - 0.042 12.8 0.3 5.3 5.9 0.1 2.6 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein G3P_antiterm PF04309.12 PRP76080.1 - 0.099 12.0 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator ERCC4 PF02732.15 PRP76085.1 - 2.2e-11 44.2 0.0 4.5e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 PRP76086.1 - 1.2e-07 32.0 0.1 2.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain SAM_1 PF00536.30 PRP76086.1 - 3.7e-05 24.1 0.4 0.00022 21.6 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP76086.1 - 0.00041 20.4 0.1 0.001 19.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1084 PF06454.11 PRP76088.1 - 0.0024 17.3 20.3 0.0057 16.1 20.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) YfzA PF14118.6 PRP76088.1 - 0.052 13.9 2.7 0.19 12.1 2.7 1.9 1 0 0 1 1 1 0 YfzA-like protein DUF2070 PF09843.9 PRP76088.1 - 2.4 6.3 17.4 4.6 5.4 17.0 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Guanylate_cyc PF00211.20 PRP76089.1 - 3.5e-53 179.9 0.0 3.2e-30 105.1 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PH PF00169.29 PRP76090.1 - 5.6e-17 62.2 0.0 2.4e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 PRP76090.1 - 1.7e-07 31.3 0.1 4e-06 26.9 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 PRP76090.1 - 0.0011 19.4 0.2 0.014 15.8 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PRP76090.1 - 0.0025 18.1 0.0 0.0096 16.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain NPV_P10 PF05531.12 PRP76090.1 - 0.014 15.9 1.0 0.033 14.7 0.4 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Dynamitin PF04912.14 PRP76090.1 - 0.095 12.0 1.0 1.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Dynamitin Pkinase_Tyr PF07714.17 PRP76091.1 - 2.2e-81 273.0 0.2 3.1e-81 272.5 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76091.1 - 1.3e-48 165.6 0.0 2e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP76091.1 - 1.4e-05 24.6 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP76091.1 - 0.012 14.6 0.1 0.023 13.7 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP76091.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EphA2_TM PF14575.6 PRP76091.1 - 0.027 15.3 0.4 0.074 13.9 0.4 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PRP76091.1 - 0.081 13.0 4.1 0.2 11.7 4.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LapA_dom PF06305.11 PRP76091.1 - 0.1 12.4 0.5 0.25 11.2 0.5 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TMEM154 PF15102.6 PRP76091.1 - 0.17 11.8 0.3 0.43 10.5 0.3 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4381 PF14316.6 PRP76091.1 - 0.25 11.6 0.2 0.46 10.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Adeno_E3_CR2 PF02439.15 PRP76091.1 - 0.68 9.7 4.0 1.7 8.5 4.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CcmD PF04995.14 PRP76091.1 - 0.76 9.9 4.1 1.7 8.8 4.1 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) HTH_50 PF18024.1 PRP76092.1 - 0.0044 16.6 0.1 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 PRP76092.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease RXLR_WY PF18634.1 PRP76092.1 - 0.0053 16.7 0.0 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 RXLR phytopathogen effector protein WY-domain DDE_Tnp_4 PF13359.6 PRP76092.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease EF-hand_1 PF00036.32 PRP76094.1 - 1.8e-13 49.0 0.0 0.00019 20.8 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PRP76094.1 - 4.7e-11 43.0 0.0 1.8e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP76094.1 - 1.4e-10 40.2 0.0 0.0029 17.4 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 PRP76094.1 - 1.6e-08 33.7 0.0 0.00052 19.4 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PRP76094.1 - 1.1e-07 31.6 0.0 0.079 12.8 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair Ndc1_Nup PF09531.10 PRP76095.1 - 0.33 9.6 7.2 0.36 9.5 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tubulin PF00091.25 PRP76096.1 - 3.4e-41 141.6 0.1 6.1e-41 140.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 PRP76096.1 - 1.3e-31 108.8 1.5 1.3e-31 108.8 1.5 1.9 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 PRP76096.1 - 2.6e-05 23.6 3.2 0.013 14.7 1.3 2.6 1 1 1 2 2 2 2 Tubulin like Ank_2 PF12796.7 PRP76097.1 - 1.9e-13 50.8 0.0 1.5e-06 28.7 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP76097.1 - 7.3e-12 44.4 0.1 0.0015 18.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PRP76097.1 - 3.8e-11 43.0 0.1 0.0062 16.8 0.0 4.3 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP76097.1 - 6.7e-10 39.3 1.9 0.018 15.6 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP76097.1 - 4.5e-07 30.0 0.0 2 9.0 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat SPT16 PF08644.11 PRP76098.1 - 8.5e-44 149.4 0.7 3e-43 147.6 0.1 2.4 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 PRP76098.1 - 3.3e-38 131.0 0.0 7.2e-38 129.9 0.0 1.6 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 PRP76098.1 - 6e-28 98.0 0.0 1.1e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 PRP76098.1 - 8.6e-18 64.5 0.0 1.9e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like YL1 PF05764.13 PRP76098.1 - 0.0028 17.8 16.1 0.0028 17.8 16.1 2.5 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 PRP76098.1 - 7.4 4.7 23.9 0.11 10.8 8.0 2.2 2 0 0 2 2 2 0 CDC45-like protein Arf PF00025.21 PRP76099.1 - 2.2e-72 242.2 0.2 2.8e-72 241.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PRP76099.1 - 2.8e-14 53.0 0.0 3.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PRP76099.1 - 7.9e-14 51.6 0.6 4.8e-08 32.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PRP76099.1 - 1.4e-13 51.1 0.0 2.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP76099.1 - 1.1e-12 47.8 0.0 1.5e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 PRP76099.1 - 1.2e-10 41.2 0.0 1.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP76099.1 - 5.1e-07 29.8 0.0 9.3e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP76099.1 - 0.00039 20.0 0.0 0.0091 15.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 PRP76099.1 - 0.0006 20.4 0.0 0.001 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 PRP76099.1 - 0.0055 15.7 0.0 0.44 9.5 0.0 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 PRP76099.1 - 0.0096 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 PRP76099.1 - 0.024 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 PRP76099.1 - 0.12 12.8 0.1 0.49 10.9 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Glyoxalase PF00903.25 PRP76100.1 - 1.5e-22 80.2 1.8 2.5e-15 56.8 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 PRP76100.1 - 6.4e-09 36.1 0.2 2.6e-08 34.2 0.1 1.9 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 PRP76100.1 - 2.5e-07 30.9 0.1 0.012 15.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PRP76100.1 - 8.5e-06 26.0 0.1 0.024 14.7 0.5 3.4 1 1 1 2 2 2 2 Glyoxalase-like domain Laminin_G_3 PF13385.6 PRP76101.1 - 8.9e-23 81.1 0.1 1.9e-22 80.0 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 PRP76101.1 - 0.00014 22.5 0.1 0.00028 21.5 0.1 1.4 1 0 0 1 1 1 1 Laminin G domain Peptidase_S10 PF00450.22 PRP76107.1 - 1.3e-125 420.1 1.0 1.9e-125 419.6 1.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Aldedh PF00171.22 PRP76109.1 - 3.6e-150 500.5 0.0 5e-150 500.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 PRP76109.1 - 0.00082 18.9 0.1 0.0032 17.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) LEA_4 PF02987.16 PRP76110.1 - 2.6e-21 75.4 162.8 3.8e-07 30.1 16.4 11.4 3 2 9 12 12 12 9 Late embryogenesis abundant protein Apolipoprotein PF01442.18 PRP76110.1 - 0.00032 20.6 80.5 0.019 14.8 22.8 4.1 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain YtxH PF12732.7 PRP76110.1 - 0.0096 16.4 113.8 0.43 11.1 16.6 9.3 1 1 4 5 5 5 2 YtxH-like protein DUF883 PF05957.13 PRP76110.1 - 0.094 13.3 100.5 0.5 11.0 12.8 8.5 2 1 8 10 10 10 0 Bacterial protein of unknown function (DUF883) RGS PF00615.19 PRP76112.1 - 5.5e-21 75.0 3.8 1.1e-20 74.0 3.8 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain TyeA PF09059.10 PRP76112.1 - 0.097 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 TyeA PAZ_siRNAbind PF12212.8 PRP76112.1 - 0.48 10.2 2.4 8.5 6.2 0.3 2.7 2 1 1 3 3 3 0 PAZ domain PIF1 PF05970.14 PRP76114.1 - 1.3e-30 106.8 1.2 5.5e-30 104.8 0.1 2.0 2 0 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 PRP76114.1 - 8.2e-14 51.8 0.0 1.5e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP76114.1 - 1.4e-09 38.5 0.0 4.3e-09 36.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP76114.1 - 0.00014 22.1 0.1 0.00077 19.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PRP76114.1 - 0.001 18.5 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PRP76114.1 - 0.0022 18.0 0.0 0.0057 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 PRP76114.1 - 0.0052 16.7 0.1 0.023 14.6 0.1 2.0 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 PRP76114.1 - 0.015 15.7 0.1 0.046 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PRP76114.1 - 0.026 15.0 0.0 0.056 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PRP76114.1 - 0.089 12.7 0.1 0.23 11.4 0.1 1.7 1 0 0 1 1 1 0 NACHT domain VirE PF05272.11 PRP76117.1 - 2.6e-05 24.1 0.0 4.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Virulence-associated protein E Zeta_toxin PF06414.12 PRP76117.1 - 0.011 15.0 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 PRP76117.1 - 0.064 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 PRP76117.1 - 0.092 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DAP3 PF10236.9 PRP76117.1 - 0.2 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Kei1 PF08552.11 PRP76120.1 - 0.98 9.3 5.0 1.7 8.4 5.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LPD24 PF18839.1 PRP76121.1 - 0.1 12.9 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 24 D123 PF07065.14 PRP76125.1 - 7e-89 298.0 1.4 1.9e-87 293.3 1.4 2.0 1 1 0 1 1 1 1 D123 FH2 PF02181.23 PRP76127.1 - 1.9e-73 247.8 0.3 1.9e-73 247.8 0.3 2.5 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PRP76127.1 - 8.7e-27 94.0 4.6 2.8e-26 92.4 4.6 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP76127.1 - 5.2e-24 84.8 2.1 5.2e-24 84.8 2.1 3.7 5 0 0 5 5 5 1 Diaphanous GTPase-binding Domain C2 PF00168.30 PRP76127.1 - 2.1e-11 44.0 0.0 6.9e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 C2 domain DUF3361 PF11841.8 PRP76127.1 - 0.0047 16.9 1.3 0.089 12.7 2.6 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) ATP-synt_E PF05680.12 PRP76127.1 - 0.89 9.9 3.4 2.2 8.7 0.1 3.2 3 0 0 3 3 3 0 ATP synthase E chain Med30 PF11315.8 PRP76127.1 - 4.3 7.5 8.6 0.49 10.6 0.1 3.7 4 0 0 4 4 4 0 Mediator complex subunit 30 G8 PF10162.9 PRP76128.1 - 4.2e-20 72.1 0.1 2e-19 69.9 0.1 2.2 1 0 0 1 1 1 1 G8 domain DUF2190 PF09956.9 PRP76128.1 - 0.52 10.8 4.0 3.4 8.2 2.1 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2190) Carboxyl_trans PF01039.22 PRP76129.1 - 1.6e-149 498.7 0.2 1.9e-149 498.5 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 PRP76129.1 - 0.028 13.9 0.1 0.64 9.5 0.0 2.1 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) TPR_19 PF14559.6 PRP76130.1 - 1.6e-09 38.1 0.0 0.0085 16.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP76130.1 - 4.6e-09 35.7 0.0 0.007 16.4 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP76130.1 - 1.2e-06 28.1 0.0 0.03 14.1 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP76130.1 - 1.8e-06 27.9 0.2 0.075 13.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP76130.1 - 4.6e-06 26.4 0.0 0.029 14.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP76130.1 - 1.1e-05 25.7 0.4 0.065 13.5 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP76130.1 - 3.7e-05 23.8 0.0 0.075 13.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP76130.1 - 0.0001 22.8 0.0 7.5 7.7 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP76130.1 - 0.0049 16.3 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 MalT-like TPR region DUF4919 PF16266.5 PRP76130.1 - 0.009 16.0 0.1 0.033 14.2 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4919) TPR_16 PF13432.6 PRP76130.1 - 0.0099 16.5 0.0 8.7 7.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP76130.1 - 0.011 15.8 0.0 0.63 10.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PRP76130.1 - 0.025 15.2 0.1 40 5.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP76130.1 - 0.032 13.9 0.0 8.7 6.1 0.0 2.7 2 0 0 2 2 2 0 TPR repeat DUF3808 PF10300.9 PRP76130.1 - 0.058 12.1 0.1 0.086 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) RPN7 PF10602.9 PRP76130.1 - 0.064 13.0 0.1 0.44 10.2 0.2 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 PknG_TPR PF16918.5 PRP76130.1 - 0.16 10.6 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat HNH_2 PF13391.6 PRP76132.1 - 9.4e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease MLVIN_C PF18697.1 PRP76132.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Guanylate_cyc PF00211.20 PRP76133.1 - 1e-40 139.4 0.1 5.9e-30 104.2 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain TMEM154 PF15102.6 PRP76133.1 - 3.6e-05 23.7 5.3 0.0021 17.9 0.8 2.6 2 0 0 2 2 2 2 TMEM154 protein family FokI_C PF02980.16 PRP76133.1 - 0.00067 19.7 0.0 1.9 8.5 0.0 3.0 3 0 0 3 3 3 2 Restriction endonuclease FokI, catalytic domain PIG-P PF08510.12 PRP76133.1 - 0.0022 17.9 5.5 0.2 11.6 0.5 2.7 2 0 0 2 2 2 2 PIG-P SAM_DrpA PF18255.1 PRP76133.1 - 0.015 15.6 0.7 13 6.1 0.0 3.1 3 0 0 3 3 3 0 DNA processing protein A sterile alpha motif domain HAMP PF00672.25 PRP76133.1 - 0.023 15.1 0.0 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 HAMP domain Shisa PF13908.6 PRP76133.1 - 0.026 14.8 1.9 0.44 10.8 0.2 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator dCache_1 PF02743.18 PRP76133.1 - 0.029 14.2 0.2 0.093 12.5 0.2 1.8 1 0 0 1 1 1 0 Cache domain R2K_2 PF18299.1 PRP76133.1 - 0.047 13.6 0.0 15 5.5 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 Baculo_gp64 PF03273.13 PRP76133.1 - 0.051 12.4 1.8 3.7 6.3 0.1 2.7 3 0 0 3 3 3 0 Baculovirus gp64 envelope glycoprotein family DUF4446 PF14584.6 PRP76133.1 - 0.052 13.5 4.7 1.5 8.8 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Cas_Csy4 PF09618.10 PRP76133.1 - 0.075 13.2 0.1 18 5.4 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Sigma_reg_N PF13800.6 PRP76133.1 - 0.087 13.1 11.6 0.57 10.5 0.8 3.2 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF2207 PF09972.9 PRP76133.1 - 0.13 11.0 4.6 2 7.1 0.9 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Cellulose_synt PF03552.14 PRP76133.1 - 0.13 10.7 9.2 0.42 9.0 1.3 2.2 2 0 0 2 2 2 0 Cellulose synthase MLANA PF14991.6 PRP76133.1 - 0.3 11.4 1.3 1.9 8.8 0.1 2.3 2 0 0 2 2 2 0 Protein melan-A Claudin_2 PF13903.6 PRP76133.1 - 0.7 9.6 10.0 0.55 10.0 0.2 3.2 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF5527 PF17665.1 PRP76133.1 - 0.73 9.4 3.8 4.6 6.8 0.3 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5527) DUF996 PF06195.13 PRP76133.1 - 1 9.6 17.5 0.55 10.5 4.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF996) HemY_N PF07219.13 PRP76133.1 - 1.2 9.3 8.9 1 9.6 1.3 2.6 2 0 0 2 2 2 0 HemY protein N-terminus m04gp34like PF12216.8 PRP76133.1 - 1.4 8.5 8.0 1.8 8.0 1.1 2.4 2 0 0 2 2 2 0 Immune evasion protein 7tm_7 PF08395.12 PRP76133.1 - 1.5 7.9 11.2 4.5 6.4 2.2 2.3 2 0 0 2 2 2 0 7tm Chemosensory receptor SP_C-Propep PF08999.10 PRP76133.1 - 2.6 7.9 11.3 4.2 7.2 1.9 2.6 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide DUF5305 PF17231.2 PRP76133.1 - 3.8 6.9 5.2 11 5.4 0.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF5385 PF17359.2 PRP76133.1 - 4.2 6.9 5.3 22 4.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Vac7 PF12751.7 PRP76133.1 - 5 6.4 5.6 12 5.1 0.4 2.3 2 0 0 2 2 2 0 Vacuolar segregation subunit 7 Chordopox_A13L PF05961.11 PRP76133.1 - 8.4 6.7 7.8 2.8 8.3 0.4 2.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein EphA2_TM PF14575.6 PRP76133.1 - 9 7.3 10.2 12 6.9 0.7 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Rgp1 PF08737.10 PRP76135.1 - 1.8e-29 103.2 5.0 5.9e-21 75.1 0.8 2.3 1 1 0 2 2 2 2 Rgp1 Arrestin_N PF00339.29 PRP76135.1 - 0.034 14.2 0.1 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain ABC_trans_N PF14510.6 PRP76136.1 - 0.0047 17.5 0.1 0.013 16.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ArAE_2_N PF10337.9 PRP76137.1 - 2.3e-65 221.5 0.1 5e-65 220.4 0.1 1.6 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 PRP76137.1 - 2.5e-34 119.1 0.0 5e-34 118.1 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 Glyoxalase PF00903.25 PRP76137.1 - 5.9e-21 75.0 1.8 1.9e-14 53.9 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FUSC_2 PF13515.6 PRP76137.1 - 1.3e-09 38.2 13.1 1.3e-09 38.2 13.1 3.9 3 1 1 4 4 4 1 Fusaric acid resistance protein-like Glyoxalase_5 PF14696.6 PRP76137.1 - 6.8e-08 32.8 0.1 1.9e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 PRP76137.1 - 8e-06 26.1 0.1 0.077 13.3 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PRP76137.1 - 0.001 19.2 0.0 0.18 11.9 0.3 2.9 1 1 1 2 2 2 1 Glyoxalase-like domain RasGAP PF00616.19 PRP76137.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.7 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase F-box-like PF12937.7 PRP76138.1 - 2.3e-09 37.0 0.2 4.8e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF3506 PF12014.8 PRP76138.1 - 7.8e-06 25.9 0.0 0.00016 21.7 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 PRP76138.1 - 4.6e-05 23.2 0.6 0.00012 21.8 0.6 1.7 1 0 0 1 1 1 1 F-box domain Aldedh PF00171.22 PRP76139.1 - 7e-134 446.8 0.0 1e-133 446.2 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Radical_SAM PF04055.21 PRP76139.1 - 8.8e-20 71.7 0.7 1.8e-17 64.2 0.1 2.9 2 1 0 2 2 2 2 Radical SAM superfamily LIAS_N PF16881.5 PRP76139.1 - 1.9e-17 63.6 0.3 5.8e-17 62.1 0.3 1.9 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Guanylate_cyc PF00211.20 PRP76140.1 - 4.3e-45 153.6 0.0 3e-21 75.9 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain SRP68 PF16969.5 PRP76142.1 - 4.3e-65 220.8 23.2 1.5e-60 205.8 15.2 2.0 1 1 1 2 2 2 2 RNA-binding signal recognition particle 68 TPR_19 PF14559.6 PRP76142.1 - 0.059 13.9 0.4 0.17 12.4 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat PTS_IIA PF02255.16 PRP76142.1 - 0.065 13.3 0.3 0.27 11.3 0.1 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_10 PF13374.6 PRP76142.1 - 0.08 12.8 1.2 0.61 10.0 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP76142.1 - 0.091 12.8 6.3 0.41 10.8 0.5 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP76142.1 - 0.23 11.8 2.7 14 6.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP76142.1 - 0.48 10.7 5.9 0.91 9.8 1.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PH PF00169.29 PRP76144.1 - 2.4e-25 89.1 0.0 3e-12 47.0 0.0 3.6 2 0 0 2 2 2 2 PH domain CH PF00307.31 PRP76144.1 - 1.9e-20 73.1 0.0 7.1e-20 71.2 0.0 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP76144.1 - 0.0026 17.6 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Nudix_N_2 PF14803.6 PRP76144.1 - 1.1 9.3 3.0 1.5 8.8 0.1 2.9 2 0 0 2 2 2 0 Nudix N-terminal PP2C PF00481.21 PRP76145.1 - 4.7e-60 203.4 0.1 1e-59 202.3 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 PRP76145.1 - 0.0012 18.5 0.2 0.0052 16.4 0.2 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C DUF485 PF04341.12 PRP76147.1 - 0.011 15.6 5.8 0.015 15.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF2207 PF09972.9 PRP76147.1 - 0.019 13.8 0.6 0.017 13.9 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1616 PF07760.11 PRP76147.1 - 0.12 11.8 2.4 0.14 11.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) AC_N PF16214.5 PRP76147.1 - 0.25 10.5 1.5 0.28 10.2 1.5 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF4191 PF13829.6 PRP76147.1 - 0.55 9.5 2.5 0.7 9.2 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FtsX PF02687.21 PRP76147.1 - 0.71 10.4 9.4 2 8.9 0.8 2.0 1 1 1 2 2 2 0 FtsX-like permease family E1-E2_ATPase PF00122.20 PRP76147.1 - 1 8.8 3.9 1.3 8.5 3.9 1.1 1 0 0 1 1 1 0 E1-E2 ATPase LRR_8 PF13855.6 PRP76148.1 - 5.2e-39 131.8 49.0 5.8e-13 48.4 2.4 7.0 3 1 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PRP76148.1 - 5.9e-25 86.9 43.5 0.00013 22.3 1.4 8.9 6 2 1 9 9 9 7 Leucine Rich repeats (2 copies) Drf_GBD PF06371.13 PRP76148.1 - 6.5e-10 38.9 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PRP76148.1 - 1e-09 38.3 1.1 2.7e-09 36.9 1.1 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain LRR_1 PF00560.33 PRP76148.1 - 7.7e-08 31.8 26.6 4.6 8.2 0.1 10.4 9 2 0 9 9 9 3 Leucine Rich Repeat LRR_9 PF14580.6 PRP76148.1 - 4.6e-05 23.0 17.2 0.61 9.6 0.3 4.7 2 1 3 5 5 5 4 Leucine-rich repeat DUF2322 PF10084.9 PRP76148.1 - 0.07 13.2 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) IF-2B PF01008.17 PRP76149.1 - 1.4e-81 273.8 0.5 1.8e-81 273.5 0.5 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family TFIIA PF03153.13 PRP76149.1 - 0.078 13.0 25.1 0.12 12.3 25.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1233 PF06806.12 PRP76149.1 - 0.12 12.0 0.0 0.45 10.1 0.0 1.9 2 0 0 2 2 2 0 Putative excisionase (DUF1233) Macoilin PF09726.9 PRP76149.1 - 0.62 8.6 6.4 0.79 8.2 6.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4175 PF13779.6 PRP76149.1 - 0.73 7.7 27.4 1 7.2 27.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CCSAP PF15748.5 PRP76149.1 - 6 7.0 22.2 10 6.2 22.2 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated VirE PF05272.11 PRP76152.1 - 0.00024 20.9 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Virulence-associated protein E GCFC PF07842.12 PRP76153.1 - 1.1e-14 54.7 0.4 6.1e-13 49.0 0.4 2.4 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein AAA_22 PF13401.6 PRP76154.1 - 0.0023 18.2 0.0 0.01 16.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PRP76154.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 PRP76154.1 - 0.088 13.2 0.0 0.28 11.5 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 PRP76154.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Peptidase_C11 PF03415.14 PRP76154.1 - 0.23 10.8 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Clostripain family DUF3253 PF11625.8 PRP76155.1 - 0.026 14.7 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) DUF99 PF01949.16 PRP76156.1 - 0.005 16.3 0.6 0.0093 15.4 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF99 DUF948 PF06103.11 PRP76156.1 - 0.031 14.5 1.9 0.047 13.9 1.9 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Phage_GPO PF05929.11 PRP76156.1 - 0.1 12.2 2.9 0.14 11.7 2.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PPR_2 PF13041.6 PRP76160.1 - 7.3e-06 26.1 1.3 0.09 13.0 0.0 3.6 3 0 0 3 3 3 3 PPR repeat family PPR PF01535.20 PRP76160.1 - 0.00051 20.1 0.6 0.49 10.7 0.1 3.7 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 PRP76160.1 - 0.012 15.0 0.1 0.065 12.6 0.0 2.1 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 PRP76160.1 - 0.099 12.7 0.7 3.9 7.6 0.1 2.9 1 1 1 3 3 3 0 Pentatricopeptide repeat domain DUF89 PF01937.19 PRP76162.1 - 5.3e-101 338.1 0.8 6.5e-101 337.8 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Lycopene_cycl PF05834.12 PRP76165.1 - 0.025 13.6 6.9 0.15 11.1 0.8 2.0 1 1 1 2 2 2 0 Lycopene cyclase protein LCIB_C_CA PF18599.1 PRP76165.1 - 0.049 12.9 0.2 5.3 6.3 0.0 2.1 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF3984 PF13136.6 PRP76165.1 - 0.54 9.6 11.5 1.6 8.0 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3984) LLC1 PF14945.6 PRP76165.1 - 2.6 8.6 5.3 15 6.2 0.9 2.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Myosin_TH1 PF06017.13 PRP76166.1 - 0.0014 18.3 0.3 0.076 12.7 0.1 2.2 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding Ank_2 PF12796.7 PRP76167.1 - 7.7e-32 109.7 0.0 3.4e-10 40.4 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76167.1 - 2.7e-27 94.8 0.1 5.7e-05 23.6 0.0 6.9 2 1 6 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 PRP76167.1 - 3.6e-15 55.6 3.1 1.8 9.2 0.0 9.1 8 1 1 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 PRP76167.1 - 2.6e-14 53.1 0.1 0.047 14.0 0.0 7.7 2 1 7 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76167.1 - 4.2e-05 23.6 0.3 15 6.6 0.0 6.8 9 0 0 9 9 9 1 Ankyrin repeat Zip PF02535.22 PRP76168.1 - 5e-66 223.2 15.3 4.7e-65 220.0 15.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter ETRAMP PF09716.10 PRP76168.1 - 0.0086 16.1 2.7 4.9 7.3 0.0 3.4 3 0 0 3 3 3 2 Malarial early transcribed membrane protein (ETRAMP) Coilin_N PF15862.5 PRP76168.1 - 0.016 15.0 0.4 0.026 14.3 0.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus FAM176 PF14851.6 PRP76168.1 - 0.057 13.1 0.0 0.93 9.1 0.0 2.2 2 0 0 2 2 2 0 FAM176 family EptA_B_N PF08019.12 PRP76168.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.4 2 1 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB AIM3 PF17096.5 PRP76168.1 - 0.33 11.9 6.7 0.66 10.9 6.7 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Peptidase_S49_N PF08496.10 PRP76168.1 - 1.2 9.2 4.1 4 7.5 4.1 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4257 PF14074.6 PRP76168.1 - 3.7 7.8 6.1 3.9 7.7 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4257) ERK-JNK_inhib PF15002.6 PRP76168.1 - 9.3 5.9 8.4 16 5.1 8.4 1.3 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Pkinase_Tyr PF07714.17 PRP76169.1 - 3.7e-69 232.9 0.0 6e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76169.1 - 1.4e-49 168.8 0.0 2.2e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP76169.1 - 1.2e-24 85.8 89.4 6.1e-06 25.9 5.8 13.9 7 5 7 16 16 16 11 Leucine rich repeat LRR_4 PF12799.7 PRP76169.1 - 4.8e-16 58.6 90.1 0.022 15.2 0.1 15.8 10 5 7 18 18 18 9 Leucine Rich repeats (2 copies) Kdo PF06293.14 PRP76169.1 - 0.0024 17.2 0.1 0.0049 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRRNT_2 PF08263.12 PRP76169.1 - 0.0034 17.7 0.8 0.0034 17.7 0.8 3.6 6 0 0 6 6 6 1 Leucine rich repeat N-terminal domain Haspin_kinase PF12330.8 PRP76169.1 - 0.042 12.8 0.5 0.1 11.5 0.1 1.8 2 0 0 2 2 2 0 Haspin like kinase domain LRR_9 PF14580.6 PRP76169.1 - 0.14 11.7 21.3 0.042 13.3 1.1 5.2 5 1 1 6 6 6 0 Leucine-rich repeat Ral PF11058.8 PRP76169.1 - 1.1 8.8 7.6 60 3.3 0.1 5.2 5 0 0 5 5 5 0 Antirestriction protein Ral LRR_1 PF00560.33 PRP76169.1 - 3.5 8.5 61.3 3.1 8.7 0.1 18.2 21 2 1 22 22 22 0 Leucine Rich Repeat Pkinase PF00069.25 PRP76170.1 - 2e-43 148.7 0.0 2.2e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76170.1 - 2.8e-23 82.5 0.0 3.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP76170.1 - 4.4e-15 55.8 0.0 5.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 PRP76172.1 - 2.1e-19 69.7 0.0 4.7e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Peptidase_S74 PF13884.6 PRP76172.1 - 1.4e-14 54.1 0.0 3.2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase PAT1 PF09770.9 PRP76172.1 - 3 6.0 27.4 4.4 5.4 27.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.25 PRP76173.1 - 3.4e-72 243.0 0.0 3.9e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76173.1 - 1.3e-36 126.2 0.0 1.6e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP76173.1 - 6.2e-06 25.7 0.0 8.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP76173.1 - 0.0035 16.7 0.2 0.41 9.9 0.1 2.9 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 PRP76173.1 - 0.04 13.5 0.1 0.079 12.6 0.1 1.4 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 PRP76173.1 - 0.042 13.5 0.1 0.17 11.5 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 PRP76173.1 - 0.047 13.2 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 PRP76173.1 - 0.098 12.6 0.0 7.3 6.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family CRAL_TRIO_2 PF13716.6 PRP76174.1 - 0.01 16.0 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain RnlB_antitoxin PF15933.5 PRP76174.1 - 0.053 13.8 0.3 0.072 13.4 0.3 1.3 1 0 0 1 1 1 0 Antitoxin to bacterial toxin RNase LS or RnlA DUF1848 PF08902.11 PRP76174.1 - 0.091 12.5 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) HA2 PF04408.23 PRP76175.1 - 2.2e-22 79.4 0.0 2.2e-22 79.4 0.0 3.0 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PRP76175.1 - 1.3e-19 70.4 0.0 2.7e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PRP76175.1 - 6.6e-13 49.0 0.0 1.9e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP76175.1 - 1.4e-07 31.5 0.1 4.8e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PRP76175.1 - 0.00017 21.9 0.0 0.00063 20.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PRP76175.1 - 0.00076 19.3 0.2 0.0028 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain PWI PF01480.17 PRP76175.1 - 0.0032 17.8 0.0 0.0089 16.3 0.0 1.8 1 0 0 1 1 1 1 PWI domain T2SSE PF00437.20 PRP76175.1 - 0.0037 16.4 0.0 0.0099 15.0 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 PRP76175.1 - 0.0048 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 PRP76175.1 - 0.013 15.8 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PRP76175.1 - 0.11 12.6 1.3 1.2 9.3 0.0 3.2 3 1 0 3 3 3 0 AAA domain Cut8 PF08559.10 PRP76176.1 - 1e-18 67.8 5.5 5.7e-18 65.4 5.5 1.8 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein FOXP-CC PF16159.5 PRP76176.1 - 0.013 16.1 0.2 0.027 15.1 0.2 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 PRP76176.1 - 0.071 14.0 1.4 0.16 12.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PRP76176.1 - 0.097 13.2 0.7 0.28 11.7 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type Rota_NSP4 PF01452.16 PRP76181.1 - 0.2 11.3 1.7 0.24 11.0 0.5 1.7 1 1 1 2 2 2 0 Rotavirus non structural protein Med31 PF05669.12 PRP76181.1 - 0.66 10.0 3.4 0.39 10.8 0.3 1.9 2 0 0 2 2 2 0 SOH1 ABC_tran_Xtn PF12848.7 PRP76182.1 - 0.21 11.6 1.8 1.7 8.7 0.0 2.8 2 1 0 2 2 2 0 ABC transporter DUF1053 PF06327.14 PRP76182.1 - 0.35 11.4 5.5 2.5 8.7 0.0 3.1 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1053) RHD3 PF05879.12 PRP76185.1 - 0.0091 14.2 0.0 0.0096 14.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) RTA1 PF04479.13 PRP76186.1 - 1.7e-18 67.0 2.8 2e-18 66.8 2.8 1.1 1 0 0 1 1 1 1 RTA1 like protein NDK PF00334.19 PRP76189.1 - 3.1e-42 143.8 0.0 5.2e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 PRP76189.1 - 6.9e-15 54.5 0.3 1.2e-14 53.7 0.3 1.4 1 0 0 1 1 1 1 Dpy-30 motif IQ PF00612.27 PRP76189.1 - 2.4e-14 51.7 6.3 4.9e-05 22.8 0.5 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif FRG2 PF15315.6 PRP76189.1 - 0.041 14.1 10.8 0.061 13.5 10.8 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Ank_4 PF13637.6 PRP76190.1 - 0.0001 22.7 3.4 2.7 8.7 0.3 5.6 5 2 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP76190.1 - 0.00032 21.2 0.5 1.5 9.4 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP76190.1 - 0.018 15.5 0.4 73 4.5 0.0 5.5 7 0 0 7 7 7 0 Ankyrin repeat Ank_5 PF13857.6 PRP76190.1 - 0.25 11.7 1.7 42 4.6 0.0 4.9 4 3 2 6 6 6 0 Ankyrin repeats (many copies) tRNA_bind PF01588.20 PRP76191.1 - 8.1e-30 102.8 1.5 1.8e-29 101.7 1.5 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.6 PRP76191.1 - 3.1e-05 24.1 0.0 0.0001 22.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP76191.1 - 0.00027 21.1 0.0 0.00027 21.1 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF4554 PF15091.6 PRP76191.1 - 0.1 11.5 3.6 0.15 11.0 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) NARP1 PF12569.8 PRP76191.1 - 0.4 9.5 13.6 0.59 9.0 13.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF913 PF06025.12 PRP76191.1 - 2.2 7.2 5.3 3.2 6.7 5.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 PRP76191.1 - 2.2 8.3 4.4 3.1 7.8 4.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 PRP76191.1 - 3.7 6.2 10.5 5.2 5.7 10.5 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 PRP76191.1 - 3.9 6.6 4.6 5.1 6.2 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MCM_bind PF09739.9 PRP76191.1 - 4 5.8 10.0 5.2 5.4 10.0 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PHD PF00628.29 PRP76192.1 - 1.9e-14 53.3 6.5 3.4e-14 52.5 6.5 1.4 1 0 0 1 1 1 1 PHD-finger DUF4777 PF16007.5 PRP76192.1 - 0.0026 18.0 0.0 2 8.7 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4777) zf-PHD-like PF15446.6 PRP76192.1 - 0.022 14.4 4.9 0.1 12.2 4.9 2.2 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 PRP76192.1 - 0.027 14.4 3.6 0.067 13.1 3.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 PRP76192.1 - 0.064 12.8 2.2 0.13 11.8 2.2 1.6 1 0 0 1 1 1 0 PHD-finger DUF760 PF05542.11 PRP76192.1 - 0.12 12.7 0.0 0.74 10.2 0.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF760) zf-RING_2 PF13639.6 PRP76192.1 - 2.3 8.6 5.3 4.3 7.8 5.3 1.5 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 PRP76192.1 - 4.5 7.4 7.2 22 5.3 7.2 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger C1_2 PF03107.16 PRP76192.1 - 5.9 7.3 8.7 11 6.5 2.9 2.5 2 0 0 2 2 2 0 C1 domain RRM_1 PF00076.22 PRP76193.1 - 5.1e-42 141.5 0.0 7.6e-21 73.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PRP76193.1 - 6e-05 22.8 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 PRP76193.1 - 0.00061 19.8 0.1 0.19 11.9 0.0 2.9 2 1 0 2 2 2 1 Limkain b1 RRM_3 PF08777.11 PRP76193.1 - 0.0067 16.5 0.0 0.59 10.2 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif ATP-grasp_2 PF08442.10 PRP76193.1 - 0.041 13.4 0.0 7.7 6.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain RRM_Rrp7 PF17799.1 PRP76193.1 - 0.047 13.5 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain YflT PF11181.8 PRP76193.1 - 0.065 13.7 0.7 4.7 7.8 0.1 2.7 3 0 0 3 3 3 0 Heat induced stress protein YflT RRM_7 PF16367.5 PRP76193.1 - 0.072 13.2 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif GRIP PF01465.20 PRP76194.1 - 2.9e-12 46.3 0.1 1e-11 44.5 0.1 2.1 1 0 0 1 1 1 1 GRIP domain Sld7_N PF18636.1 PRP76195.1 - 0.05 14.0 0.0 0.052 13.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain LapA_dom PF06305.11 PRP76196.1 - 0.015 15.1 1.4 0.034 13.9 1.4 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DAG1 PF05454.11 PRP76196.1 - 0.062 12.7 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) YrhC PF14143.6 PRP76196.1 - 3.1 7.9 4.1 0.88 9.7 0.1 2.1 3 0 0 3 3 3 0 YrhC-like protein Laminin_G_3 PF13385.6 PRP76197.1 - 9.8e-14 51.8 3.3 9.8e-14 51.8 3.3 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 PRP76197.1 - 0.014 15.1 0.2 0.043 13.5 0.2 1.7 1 1 0 1 1 1 0 Pentaxin family HepII_C PF18675.1 PRP76197.1 - 0.032 14.3 0.8 1.3 9.1 0.2 2.7 2 0 0 2 2 2 0 Heparinase II C-terminal domain DENN PF02141.21 PRP76199.1 - 3.7e-24 85.7 7.1 2e-23 83.3 5.6 2.8 2 1 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 PRP76199.1 - 4.3e-10 40.2 1.4 2.2e-09 37.9 0.3 2.6 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 PRP76199.1 - 4.5e-07 29.7 1.8 1.6e-06 28.0 0.2 2.6 1 1 1 2 2 2 1 dDENN domain Ank_2 PF12796.7 PRP76200.1 - 2.7e-57 191.3 0.3 7.7e-10 39.2 0.0 9.3 4 3 4 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76200.1 - 1e-47 159.9 11.8 7.6e-05 23.2 0.1 14.3 7 6 8 15 15 15 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP76200.1 - 2.2e-32 110.7 9.9 0.034 14.5 0.0 15.1 8 4 8 16 16 16 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76200.1 - 2.2e-19 67.5 4.7 15 6.6 0.0 15.8 18 0 0 18 18 18 1 Ankyrin repeat Ank PF00023.30 PRP76200.1 - 9.4e-17 60.6 24.0 2.4 8.8 0.0 17.0 17 3 2 19 19 19 2 Ankyrin repeat Pfg27 PF09216.10 PRP76200.1 - 0.01 15.7 0.0 0.55 10.0 0.0 3.2 3 0 0 3 3 3 0 Pfg27 HTH_13 PF11972.8 PRP76200.1 - 0.057 13.5 0.1 2.2 8.4 0.1 3.3 2 0 0 2 2 2 0 HTH DNA binding domain UPF0149 PF03695.13 PRP76200.1 - 0.15 12.3 0.1 0.45 10.8 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) ADSL_C PF10397.9 PRP76200.1 - 0.42 11.2 6.5 1.6e+02 2.9 0.0 6.9 6 4 3 9 9 9 0 Adenylosuccinate lyase C-terminus p450 PF00067.22 PRP76201.1 - 6.5e-83 279.0 5.5 6.8e-82 275.7 5.5 1.9 1 1 0 1 1 1 1 Cytochrome P450 RNase_H_2 PF13482.6 PRP76201.1 - 0.017 15.1 0.3 0.041 13.9 0.2 1.7 1 1 0 1 1 1 0 RNase_H superfamily Adeno_E1B_55K PF01696.17 PRP76202.1 - 0.00058 18.7 15.2 0.096 11.4 0.0 4.4 2 1 1 4 4 4 3 Adenovirus EB1 55K protein / large t-antigen Beta_helix PF13229.6 PRP76202.1 - 0.0034 17.2 6.9 0.0034 17.2 6.9 4.9 1 1 2 3 3 3 1 Right handed beta helix region Guanylate_cyc_2 PF09778.9 PRP76203.1 - 0.019 14.4 0.2 0.038 13.4 0.2 1.5 1 0 0 1 1 1 0 Guanylylate cyclase Pentapeptide_3 PF13576.6 PRP76204.1 - 0.0052 16.9 3.4 0.15 12.2 0.1 2.8 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Pkinase_Tyr PF07714.17 PRP76206.1 - 3.5e-70 236.3 0.0 6e-70 235.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76206.1 - 4e-48 164.1 0.0 6.3e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP76206.1 - 1.2e-38 130.4 78.4 1e-05 25.8 0.8 17.2 11 4 9 20 20 20 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP76206.1 - 1.1e-28 98.8 94.8 7e-10 38.5 2.6 16.5 10 7 8 18 18 18 9 Leucine rich repeat LRR_6 PF13516.6 PRP76206.1 - 2.2e-11 42.9 68.0 1.3 9.3 0.0 21.5 25 0 0 25 25 24 4 Leucine Rich repeat LRR_1 PF00560.33 PRP76206.1 - 3.8e-07 29.7 71.4 0.29 11.8 0.0 22.1 23 4 0 23 23 20 2 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP76206.1 - 0.00041 20.6 0.1 0.0014 18.9 0.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Podoplanin PF05808.11 PRP76206.1 - 0.035 14.2 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 Podoplanin DUF1180 PF06679.12 PRP76206.1 - 0.066 13.6 0.4 0.12 12.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Kdo PF06293.14 PRP76206.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APP_amyloid PF10515.9 PRP76206.1 - 0.26 11.8 0.6 0.65 10.5 0.6 1.7 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus LRR_9 PF14580.6 PRP76206.1 - 2.4 7.7 11.9 0.95 8.9 0.0 4.5 4 2 1 6 6 6 0 Leucine-rich repeat SKG6 PF08693.10 PRP76206.1 - 7.8 6.0 12.1 18 4.9 12.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RETICULATA-like PF11891.8 PRP76208.1 - 0.083 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein RETICULATA-related SpvD PF05563.12 PRP76208.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Salmonella plasmid virulence protein SpvD Arm PF00514.23 PRP76209.1 - 7.8e-16 57.5 16.3 0.0002 21.3 0.1 7.5 7 1 1 8 8 8 4 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 PRP76209.1 - 4.9e-05 23.3 12.0 0.047 13.6 0.3 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 PRP76209.1 - 0.0023 18.3 0.2 4.7 7.7 0.0 3.5 3 1 0 3 3 3 1 HEAT repeats IFRD PF05004.13 PRP76209.1 - 0.013 14.7 1.4 0.08 12.0 1.2 2.2 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 PRP76209.1 - 0.021 14.8 2.5 1.1 9.2 0.2 3.2 2 2 0 2 2 2 0 Myosin-binding striated muscle assembly central V-ATPase_H_N PF03224.14 PRP76209.1 - 0.026 13.8 7.0 0.15 11.4 6.3 2.4 1 1 1 2 2 2 0 V-ATPase subunit H Proteasom_PSMB PF10508.9 PRP76209.1 - 0.081 11.4 6.0 0.09 11.3 0.3 2.9 2 2 2 4 4 4 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 PRP76209.1 - 0.14 12.7 1.4 57 4.4 0.0 4.1 5 0 0 5 5 5 0 HEAT-like repeat cNMP_binding PF00027.29 PRP76210.1 - 7.6e-09 35.5 0.1 4.7e-06 26.6 0.1 2.4 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PRP76210.1 - 0.0016 18.4 1.3 0.0054 16.7 1.3 2.0 1 0 0 1 1 1 1 Ion channel WH2 PF02205.20 PRP76211.1 - 4.2e-06 26.4 1.6 8e-06 25.5 1.6 1.5 1 0 0 1 1 1 1 WH2 motif Pkinase_Tyr PF07714.17 PRP76211.1 - 0.00094 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76211.1 - 0.006 16.0 0.5 0.07 12.5 0.1 2.6 3 1 1 4 4 4 1 Protein kinase domain DEC-1_N PF04625.13 PRP76211.1 - 0.3 10.0 18.9 0.59 9.1 18.9 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_60s PF00428.19 PRP76211.1 - 5.5 7.7 5.9 2.1 9.0 2.2 2.2 2 1 1 3 3 3 0 60s Acidic ribosomal protein Shisa PF13908.6 PRP76211.1 - 6.7 6.9 6.8 14 5.8 0.1 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator rve PF00665.26 PRP76213.1 - 1.5e-15 57.5 0.0 2.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PRP76213.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Esterase PF00756.20 PRP76216.1 - 7.8e-56 189.5 0.2 1e-55 189.1 0.2 1.1 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 PRP76216.1 - 3e-05 23.4 0.1 0.00012 21.5 0.1 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PRP76216.1 - 0.0017 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF3718 PF12514.8 PRP76216.1 - 0.027 14.6 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) Chlorophyllase2 PF12740.7 PRP76216.1 - 0.044 12.7 0.0 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 PRP76216.1 - 0.049 13.3 0.1 0.092 12.4 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP76216.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4574 PF15141.6 PRP76216.1 - 0.21 11.5 0.4 0.7 9.8 0.4 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Lipase PF00151.19 PRP76217.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Lipase KAP_NTPase PF07693.14 PRP76219.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.12 PRP76219.1 - 0.043 13.1 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin VirE PF05272.11 PRP76219.1 - 0.045 13.5 0.1 0.87 9.3 0.1 2.4 1 1 0 1 1 1 0 Virulence-associated protein E AAA_29 PF13555.6 PRP76219.1 - 0.068 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 PRP76219.1 - 0.08 13.4 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP76219.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain GIT_SHD PF08518.11 PRP76221.1 - 2.3 7.9 4.5 20 4.9 0.4 2.5 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT RhoGAP PF00620.27 PRP76222.1 - 1.7e-31 109.1 0.0 2.7e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MHC_II_alpha PF00993.20 PRP76222.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain WD40 PF00400.32 PRP76222.1 - 0.14 13.1 13.4 0.23 12.4 1.4 5.5 4 1 0 4 4 4 0 WD domain, G-beta repeat Arf PF00025.21 PRP76223.1 - 1.9e-76 255.4 0.2 1.9e-76 255.4 0.2 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Y_phosphatase PF00102.27 PRP76223.1 - 7.4e-68 228.6 1.1 1.2e-67 227.9 0.2 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Ank_2 PF12796.7 PRP76223.1 - 6.6e-46 154.8 6.4 4.3e-11 43.2 0.0 6.3 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP76223.1 - 1.5e-39 133.5 6.1 4.5e-07 30.0 0.1 9.4 5 3 5 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP76223.1 - 1.2e-38 130.9 0.1 4.9e-06 27.0 0.0 8.9 3 2 5 9 9 9 6 Ankyrin repeats (many copies) PH PF00169.29 PRP76223.1 - 2.1e-27 95.6 0.9 1.2e-10 41.8 0.0 3.7 3 0 0 3 3 3 3 PH domain Ank_3 PF13606.6 PRP76223.1 - 6.1e-26 87.6 6.9 0.023 15.2 0.0 12.1 13 0 0 13 13 12 4 Ankyrin repeat Ank PF00023.30 PRP76223.1 - 3e-21 74.9 11.9 0.023 15.2 0.0 10.9 11 1 1 12 12 10 5 Ankyrin repeat Roc PF08477.13 PRP76223.1 - 1.2e-12 48.1 0.0 3.2e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP76223.1 - 1.4e-11 44.2 0.0 3.7e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PRP76223.1 - 1.6e-11 44.1 0.0 3.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 PRP76223.1 - 1.9e-08 33.9 0.0 4.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 PRP76223.1 - 3.1e-08 33.2 0.2 3.1e-08 33.2 0.2 3.6 2 2 1 3 3 3 1 G-protein alpha subunit PH_8 PF15409.6 PRP76223.1 - 1.4e-06 28.5 0.0 0.043 14.1 0.0 4.1 3 0 0 3 3 3 2 Pleckstrin homology domain MMR_HSR1 PF01926.23 PRP76223.1 - 0.00017 21.6 0.1 0.00045 20.3 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PH_11 PF15413.6 PRP76223.1 - 0.00022 21.6 1.9 0.013 15.9 1.5 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain DSPc PF00782.20 PRP76223.1 - 0.0012 18.7 0.6 0.0037 17.1 0.6 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PX PF00787.24 PRP76223.1 - 0.0098 15.9 0.0 0.041 13.9 0.0 2.1 2 0 0 2 2 1 1 PX domain Y_phosphatase3 PF13350.6 PRP76223.1 - 0.028 14.4 0.2 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Spectrin PF00435.21 PRP76223.1 - 2.1 8.9 17.8 7.2 7.1 6.2 4.0 4 0 0 4 4 3 0 Spectrin repeat Epimerase PF01370.21 PRP76224.1 - 2.6e-20 72.9 0.1 1.4e-19 70.5 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PRP76224.1 - 9.4e-15 54.8 0.3 7.8e-11 42.0 0.2 2.4 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 PRP76224.1 - 3.2e-14 53.2 2.1 3.9e-14 53.0 0.3 1.9 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PRP76224.1 - 4.5e-10 39.0 0.1 5.3e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PRP76224.1 - 3e-09 36.7 0.0 7.4e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PRP76224.1 - 1.6e-08 34.0 0.1 1.8e-05 24.0 0.1 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain TrkA_N PF02254.18 PRP76224.1 - 2.1e-06 28.0 0.1 9.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 PRP76224.1 - 5.2e-05 23.5 0.1 0.0001 22.6 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 PRP76224.1 - 5.9e-05 22.6 0.1 0.00012 21.6 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP76224.1 - 0.00011 22.1 0.4 0.00023 21.2 0.2 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 PRP76224.1 - 0.00048 19.4 0.1 0.001 18.3 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_2 PF03446.15 PRP76224.1 - 0.0071 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 PRP76224.1 - 0.011 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.15 PRP76224.1 - 0.014 14.6 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 PRP76224.1 - 0.041 14.0 0.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 PRP76224.1 - 0.059 13.8 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_trans_4_2 PF13477.6 PRP76224.1 - 0.1 12.6 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like Bacillus_HBL PF05791.11 PRP76225.1 - 4.8e-05 23.3 12.0 4.8e-05 23.3 12.0 7.5 2 2 5 8 8 8 1 Bacillus haemolytic enterotoxin (HBL) Secretogranin_V PF05281.11 PRP76225.1 - 9.1 5.8 9.3 4.9 6.7 3.1 3.5 2 1 0 2 2 2 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) Radial_spoke_3 PF06098.11 PRP76228.1 - 3e-05 23.4 0.0 4.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Radial spoke protein 3 zf-RRPl_C4 PF17026.5 PRP76229.1 - 0.002 18.2 0.2 0.0055 16.8 0.1 1.7 2 0 0 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_4 PF14447.6 PRP76229.1 - 0.34 10.8 2.7 0.75 9.7 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PRP76229.1 - 0.54 10.2 4.9 1.2 9.0 4.9 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acetyltransf_1 PF00583.25 PRP76230.1 - 0.00097 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PRP76230.1 - 0.0016 18.4 0.0 0.0053 16.7 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 PRP76230.1 - 0.0035 17.7 0.0 0.0068 16.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP76230.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP76230.1 - 0.016 15.4 0.0 0.05 13.7 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 PRP76230.1 - 0.11 12.3 0.3 0.25 11.0 0.3 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ HATPase_c PF02518.26 PRP76231.1 - 9e-28 97.0 0.3 2.2e-27 95.8 0.3 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP76231.1 - 2.3e-26 92.2 2.2 2e-23 82.7 1.0 3.0 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 PRP76231.1 - 8.4e-17 61.0 0.0 8.3e-16 57.8 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 PRP76231.1 - 1.8e-05 24.6 0.0 0.035 14.2 0.0 2.9 2 0 0 2 2 2 2 PAS domain FleQ PF06490.11 PRP76231.1 - 5.8e-05 23.4 1.3 0.0014 18.9 0.0 3.1 3 1 0 3 3 3 1 Flagellar regulatory protein FleQ PAS PF00989.25 PRP76231.1 - 0.00012 22.1 0.0 0.56 10.2 0.0 3.3 3 0 0 3 3 3 2 PAS fold HATPase_c_3 PF13589.6 PRP76231.1 - 0.00083 19.2 0.1 0.0036 17.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribophorin_II PF05817.14 PRP76231.1 - 0.13 10.8 0.0 0.31 9.6 0.0 1.6 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II C8 PF08742.11 PRP76231.1 - 0.37 11.2 2.8 8 7.0 0.3 2.7 2 0 0 2 2 2 0 C8 domain Sugar_tr PF00083.24 PRP76232.1 - 9.9e-40 136.7 28.8 1.3e-39 136.4 28.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP76232.1 - 4.4e-30 104.8 46.0 1.3e-23 83.6 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PRP76232.1 - 1.3e-06 27.3 1.4 1.3e-06 27.3 1.4 3.5 3 1 0 3 3 3 3 MFS/sugar transport protein TauD PF02668.16 PRP76233.1 - 9.2e-38 130.6 0.0 1.3e-37 130.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 PRP76233.1 - 2.1e-14 53.9 1.2 5e-14 52.7 0.2 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF971) CsiD PF08943.10 PRP76233.1 - 0.0032 16.6 0.0 0.41 9.7 0.0 2.2 2 0 0 2 2 2 2 CsiD Adap_comp_sub PF00928.21 PRP76234.1 - 3.6e-21 75.7 0.5 5.9e-21 75.0 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PRP76234.1 - 2.8e-05 24.1 0.3 5.1e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain IQ PF00612.27 PRP76236.1 - 8e-44 143.3 156.6 0.00043 19.8 2.0 25.6 27 0 0 27 27 27 20 IQ calmodulin-binding motif CH PF00307.31 PRP76236.1 - 3.4e-14 52.9 0.0 6.3e-06 26.3 0.1 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP76236.1 - 1.6e-11 43.9 0.4 1.7e-09 37.4 0.0 3.1 3 0 0 3 3 3 1 CAMSAP CH domain ASH PF15780.5 PRP76236.1 - 0.11 12.8 0.6 0.61 10.3 0.0 2.5 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Taxilin PF09728.9 PRP76238.1 - 0.00044 19.5 31.0 0.00044 19.5 31.0 2.9 1 1 2 3 3 3 1 Myosin-like coiled-coil protein ApoO PF09769.9 PRP76238.1 - 0.3 11.0 6.7 0.62 10.0 0.1 3.2 2 2 0 2 2 2 0 Apolipoprotein O SH3_9 PF14604.6 PRP76239.1 - 9.8e-12 44.6 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP76239.1 - 2e-09 37.0 0.0 3.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP76239.1 - 5.8e-09 35.4 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 PRP76239.1 - 2.9e-06 27.4 0.1 7.8e-06 26.1 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1494 PF07379.11 PRP76239.1 - 0.041 13.7 0.3 0.074 12.9 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1494) Spore_III_AB PF09548.10 PRP76239.1 - 0.082 13.0 2.0 0.11 12.6 1.1 1.7 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Glyco_hydro_38N PF01074.22 PRP76241.1 - 7e-77 258.6 0.4 1.3e-76 257.8 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP76241.1 - 3.6e-23 82.8 1.2 5.3e-16 59.3 0.4 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP76241.1 - 2.6e-09 37.1 0.1 8.7e-09 35.4 0.1 2.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PRP76241.1 - 0.0019 18.3 0.1 0.0052 16.9 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF1831 PF08866.10 PRP76241.1 - 0.028 14.9 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Putative amino acid metabolism Aminotran_1_2 PF00155.21 PRP76242.1 - 2.2e-61 208.1 0.0 2.5e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PRP76242.1 - 2.2e-08 33.8 0.0 3.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 PRP76242.1 - 1.2e-05 24.5 0.0 2.8e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PRP76242.1 - 1.4e-05 23.8 0.0 3e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 PRP76242.1 - 0.0004 19.8 0.0 0.00062 19.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.21 PRP76242.1 - 0.0062 15.2 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III SRP54 PF00448.22 PRP76242.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain zf-RING_9 PF13901.6 PRP76243.1 - 1.8e-30 106.5 2.7 2.1e-30 106.2 2.7 1.0 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon zf-Sec23_Sec24 PF04810.15 PRP76243.1 - 0.058 13.5 1.1 0.058 13.5 1.1 2.7 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Prok-RING_1 PF14446.6 PRP76243.1 - 0.24 11.4 13.7 3 7.9 13.7 2.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.22 PRP76243.1 - 0.32 10.9 13.8 1 9.3 11.0 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ_CXXCXGXG PF00684.19 PRP76243.1 - 0.51 10.7 10.6 1.5 9.3 10.3 1.9 1 1 0 1 1 1 0 DnaJ central domain zf-RING_4 PF14570.6 PRP76243.1 - 1.4 8.7 12.7 0.24 11.2 6.7 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-B_box PF00643.24 PRP76243.1 - 2.1 8.5 14.8 0.18 12.0 3.1 2.5 2 1 0 2 2 2 0 B-box zinc finger PHD PF00628.29 PRP76243.1 - 5.6 6.9 14.7 16 5.5 7.5 3.1 1 1 1 2 2 2 0 PHD-finger Pkinase_Tyr PF07714.17 PRP76247.1 - 4.4e-60 203.1 0.0 6.2e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76247.1 - 8.3e-50 169.6 0.0 1.3e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_18 PF00704.28 PRP76247.1 - 5.1e-26 92.1 0.0 9.1e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Metallophos PF00149.28 PRP76247.1 - 6.2e-18 66.0 0.6 1.1e-17 65.2 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PRP76247.1 - 2.8e-12 47.1 1.5 7e-12 45.8 0.3 2.4 2 0 0 2 2 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 PRP76247.1 - 6e-07 30.2 0.0 1.7e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Kinase-like PF14531.6 PRP76247.1 - 7.7e-06 25.4 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP76247.1 - 5.6e-05 22.6 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family fn3_PAP PF17808.1 PRP76247.1 - 0.00025 21.1 0.2 0.0065 16.6 0.2 2.9 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Syndecan PF01034.20 PRP76247.1 - 0.01 15.7 1.6 0.01 15.7 1.6 2.1 2 0 0 2 2 2 0 Syndecan domain Pkinase_fungal PF17667.1 PRP76247.1 - 0.04 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF5305 PF17231.2 PRP76247.1 - 0.043 13.2 0.1 0.095 12.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2189 PF09955.9 PRP76247.1 - 0.061 13.6 0.1 0.2 11.9 0.1 1.8 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) EphA2_TM PF14575.6 PRP76247.1 - 0.092 13.6 0.0 0.52 11.2 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EVC2_like PF12297.8 PRP76247.1 - 0.098 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein RIFIN PF02009.16 PRP76247.1 - 0.1 12.5 0.3 0.17 11.8 0.3 1.3 1 0 0 1 1 1 0 Rifin LapA_dom PF06305.11 PRP76247.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ank_2 PF12796.7 PRP76248.1 - 1.3e-08 35.3 0.0 0.0075 16.8 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76248.1 - 3.5e-08 33.8 0.0 0.0013 19.3 0.0 4.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) RNA_pol_3_Rpc31 PF11705.8 PRP76248.1 - 0.00032 21.0 8.5 0.00062 20.1 8.5 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 F-box PF00646.33 PRP76248.1 - 0.00079 19.2 0.1 0.0027 17.6 0.1 1.9 1 0 0 1 1 1 1 F-box domain SDA1 PF05285.12 PRP76248.1 - 0.00089 18.8 14.0 0.0014 18.1 14.0 1.2 1 0 0 1 1 1 1 SDA1 Ank_5 PF13857.6 PRP76248.1 - 0.0026 18.0 0.0 1.3 9.4 0.1 4.0 2 2 2 4 4 4 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP76248.1 - 0.0029 17.5 0.2 0.0085 16.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like Nop14 PF04147.12 PRP76248.1 - 0.0076 14.5 14.4 0.011 14.0 14.4 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2722 PF10846.8 PRP76248.1 - 0.058 12.3 1.8 0.086 11.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TRAP_alpha PF03896.16 PRP76248.1 - 0.06 12.5 7.9 0.099 11.8 7.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.9 PRP76248.1 - 0.079 12.1 12.1 0.13 11.4 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NTP_transf_2 PF01909.23 PRP76248.1 - 0.26 11.6 2.9 1.7 9.0 0.0 3.0 3 0 0 3 3 3 0 Nucleotidyltransferase domain DNA_pol_phi PF04931.13 PRP76248.1 - 0.39 8.8 18.0 0.57 8.2 18.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Zip PF02535.22 PRP76248.1 - 0.51 9.5 2.7 0.8 8.9 2.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 PRP76248.1 - 0.56 9.1 2.9 0.89 8.5 2.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PI3K_1B_p101 PF10486.9 PRP76248.1 - 0.56 7.9 8.1 0.86 7.3 8.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 PRP76248.1 - 0.69 8.6 1.5 1 8.0 1.5 1.1 1 0 0 1 1 1 0 Presenilin BUD22 PF09073.10 PRP76248.1 - 0.74 9.1 13.9 0.86 8.9 12.9 1.5 2 0 0 2 2 2 0 BUD22 RPN2_C PF18004.1 PRP76248.1 - 0.79 9.6 11.8 2 8.3 11.7 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPP4R2 PF09184.11 PRP76248.1 - 0.92 9.0 18.9 1.6 8.2 18.9 1.3 1 0 0 1 1 1 0 PPP4R2 Tim54 PF11711.8 PRP76248.1 - 1.7 7.4 8.9 2.7 6.7 8.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4820 PF16091.5 PRP76248.1 - 2.2 7.6 6.7 4.3 6.6 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MAP17 PF15807.5 PRP76248.1 - 2.2 8.5 10.9 5.1 7.3 10.9 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4746 PF15928.5 PRP76248.1 - 2.3 7.5 19.7 3.9 6.8 19.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TMEM51 PF15345.6 PRP76248.1 - 2.6 7.9 4.2 4.3 7.1 4.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 FAM176 PF14851.6 PRP76248.1 - 2.6 7.7 11.8 5.7 6.6 11.8 1.5 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 PRP76248.1 - 3.3 7.7 11.2 7.8 6.5 11.2 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 PRP76248.1 - 4.6 7.0 12.2 8.6 6.1 12.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.13 PRP76248.1 - 6.4 5.7 20.3 12 4.8 20.3 1.3 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.11 PRP76248.1 - 6.4 6.0 21.3 11 5.3 21.3 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Serinc PF03348.15 PRP76248.1 - 8.2 5.2 4.9 12 4.6 4.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NAD_binding_6 PF08030.12 PRP76249.1 - 2.4e-35 121.9 0.0 4.2e-35 121.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PRP76249.1 - 1.2e-20 73.9 13.1 1.3e-20 73.8 11.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 PRP76249.1 - 1.8e-17 63.4 0.0 4.7e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 PRP76249.1 - 0.00013 22.3 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 PRP76249.1 - 0.0018 18.9 0.4 0.011 16.4 0.0 2.4 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain PPV_E2_C PF00511.17 PRP76249.1 - 0.012 15.8 0.5 8.6 6.6 0.0 3.1 2 0 0 2 2 2 0 E2 (early) protein, C terminal cNMP_binding PF00027.29 PRP76250.1 - 4.5e-31 106.8 0.1 3.1e-20 72.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Peptidase_S24 PF00717.23 PRP76250.1 - 6e-08 32.5 0.1 2.8e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase S24-like Lactamase_B_2 PF12706.7 PRP76250.1 - 3.9e-05 23.3 0.1 7.6e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP76250.1 - 0.0066 16.5 1.5 0.018 15.0 1.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Ank_2 PF12796.7 PRP76251.1 - 7.5e-45 151.4 0.1 3.2e-09 37.3 0.0 5.8 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76251.1 - 1.3e-27 95.8 2.2 0.00034 21.1 0.2 9.1 4 3 5 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP76251.1 - 2.8e-24 84.9 1.7 0.0018 18.5 0.0 9.4 5 3 6 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76251.1 - 1.3e-13 49.7 0.1 1.7 9.5 0.0 10.6 11 1 0 11 11 11 2 Ankyrin repeat Ank PF00023.30 PRP76251.1 - 3e-12 46.4 1.5 1.6 9.3 0.0 9.2 9 3 0 9 9 9 2 Ankyrin repeat Birna_VP3 PF01767.16 PRP76251.1 - 0.004 17.3 0.4 41 4.2 0.0 4.9 1 1 1 3 3 3 0 Birnavirus VP3 protein YlzJ PF14035.6 PRP76251.1 - 0.016 15.4 0.0 6 7.2 0.0 4.1 5 0 0 5 5 5 0 YlzJ-like protein Anthrax_toxA PF03497.16 PRP76251.1 - 0.044 13.9 0.1 4.3 7.4 0.0 3.3 3 1 0 4 4 4 0 Anthrax toxin LF subunit ADSL_C PF10397.9 PRP76251.1 - 1 10.0 4.7 20 5.8 0.1 4.7 3 2 2 5 5 5 0 Adenylosuccinate lyase C-terminus VWA_3_C PF18571.1 PRP76251.1 - 9.2 6.2 6.9 11 6.0 0.1 4.2 5 1 0 5 5 5 0 von Willebrand factor type A C-terminal domain cNMP_binding PF00027.29 PRP76252.1 - 3e-16 59.3 0.0 3.6e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PLDc PF00614.22 PRP76252.1 - 7.4e-16 57.6 0.2 7.9e-10 38.5 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PRP76252.1 - 9.1e-15 54.7 0.1 1.8e-08 34.4 0.1 3.1 2 1 0 2 2 2 2 PLD-like domain RasGEF PF00617.19 PRP76252.1 - 3.9e-13 50.0 0.0 1.4e-12 48.2 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP76252.1 - 2.2e-06 27.9 0.0 7.4e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif GRAM PF02893.20 PRP76252.1 - 8e-05 22.5 0.0 0.00022 21.1 0.0 1.8 1 0 0 1 1 1 1 GRAM domain PH PF00169.29 PRP76252.1 - 0.00044 20.7 0.1 0.012 16.2 0.0 3.1 3 0 0 3 3 3 1 PH domain PhyH PF05721.13 PRP76253.1 - 4.6e-19 69.5 0.0 5.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4543 PF15076.6 PRP76256.1 - 2 8.6 5.8 2 8.6 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4543) Di19_C PF14571.6 PRP76256.1 - 7.3 7.2 10.6 1.6 9.3 2.8 2.6 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal PseudoU_synth_2 PF00849.22 PRP76257.1 - 6.2e-30 104.4 0.0 8.2e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Zip PF02535.22 PRP76258.1 - 1.5e-32 113.2 0.1 2.1e-32 112.7 0.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter FeoB_C PF07664.12 PRP76258.1 - 1.5 8.6 5.6 6.9 6.4 0.0 3.5 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus E1-E2_ATPase PF00122.20 PRP76258.1 - 3.6 7.1 6.1 1.1 8.7 0.1 2.8 2 1 1 3 3 3 0 E1-E2 ATPase ASC PF00858.24 PRP76259.1 - 3.8e-05 22.8 11.8 0.033 13.1 0.8 3.1 1 1 1 3 3 3 3 Amiloride-sensitive sodium channel F-box-like PF12937.7 PRP76260.1 - 1.7e-08 34.3 0.3 3.5e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP76260.1 - 1.4e-07 31.2 0.1 3.1e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain EamA PF00892.20 PRP76261.1 - 6.4e-28 97.6 40.8 2.9e-14 53.4 21.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family PIRT PF15099.6 PRP76261.1 - 0.24 11.0 0.0 0.24 11.0 0.0 3.8 2 1 2 4 4 4 0 Phosphoinositide-interacting protein family TMEM174 PF15029.6 PRP76261.1 - 0.59 9.8 3.0 17 5.0 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 174 DSPc PF00782.20 PRP76262.1 - 1.4e-33 115.5 0.1 2.5e-33 114.7 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain EF-hand_4 PF12763.7 PRP76262.1 - 1.8e-05 24.6 0.4 0.0032 17.4 0.1 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Y_phosphatase PF00102.27 PRP76262.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase EF-hand_6 PF13405.6 PRP76262.1 - 0.066 13.2 3.3 0.42 10.7 0.5 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 PRP76262.1 - 0.099 12.2 4.0 0.5 10.0 0.4 3.1 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 PRP76262.1 - 0.15 12.6 4.5 0.36 11.3 2.2 2.5 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 PRP76262.1 - 2.4 8.1 6.6 0.34 10.8 1.6 2.2 2 0 0 2 2 2 0 EF-hand domain pair ATP-grasp_3 PF02655.14 PRP76264.1 - 6.8e-05 23.0 0.0 0.0004 20.5 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 PRP76264.1 - 0.00033 20.4 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Ank_2 PF12796.7 PRP76265.1 - 3.3e-62 207.1 0.0 2.1e-11 44.2 0.0 7.0 5 1 4 9 9 9 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76265.1 - 6.8e-46 154.1 2.8 1.1e-06 29.0 0.0 11.1 5 3 4 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP76265.1 - 3e-33 113.4 0.4 0.053 13.9 0.0 14.1 3 2 10 14 14 14 9 Ankyrin repeats (many copies) Ank PF00023.30 PRP76265.1 - 1.6e-25 88.4 7.0 0.2 12.1 0.0 14.4 14 3 2 17 17 17 7 Ankyrin repeat Ank_3 PF13606.6 PRP76265.1 - 6e-23 78.4 0.2 0.24 12.1 0.0 13.4 14 0 0 14 14 14 3 Ankyrin repeat VWA_3_C PF18571.1 PRP76265.1 - 8e-05 22.4 11.8 20 5.1 0.0 9.1 9 1 1 10 10 10 1 von Willebrand factor type A C-terminal domain Anthrax_toxA PF03497.16 PRP76265.1 - 0.0036 17.4 0.3 7.5 6.7 0.0 4.4 3 3 1 5 5 5 1 Anthrax toxin LF subunit DUF1110 PF06533.12 PRP76265.1 - 0.088 12.8 8.8 13 5.7 0.1 5.9 3 3 5 8 8 8 0 Protein of unknown function (DUF1110) Vps4_C PF09336.10 PRP76266.1 - 0.022 14.7 0.1 0.028 14.4 0.1 1.2 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Ank_4 PF13637.6 PRP76269.1 - 0.0011 19.5 0.2 4 8.1 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Rap_GAP PF02145.15 PRP76271.1 - 1.2e-65 220.5 0.0 2e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP zf-4CXXC_R1 PF10497.9 PRP76272.1 - 0.015 15.5 5.6 0.032 14.5 5.6 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PDEase_I PF00233.19 PRP76273.1 - 1.6e-83 280.1 2.2 3.1e-83 279.1 2.2 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 PRP76273.1 - 7.1e-62 207.9 0.0 7.5e-18 65.4 0.0 5.1 5 0 0 5 5 5 4 GAF domain GAF_2 PF13185.6 PRP76273.1 - 1.7e-43 148.3 0.0 5.3e-11 43.0 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 PRP76273.1 - 7.3e-27 94.3 0.0 4.1e-08 33.6 0.0 4.8 4 0 0 4 4 4 4 GAF domain dCache_1 PF02743.18 PRP76273.1 - 7.5e-06 25.9 1.7 4.3 7.0 0.0 4.4 4 0 0 4 4 4 3 Cache domain Tropomyosin PF00261.20 PRP76273.1 - 0.0036 16.7 8.3 0.0068 15.8 8.3 1.4 1 0 0 1 1 1 1 Tropomyosin TMF_DNA_bd PF12329.8 PRP76273.1 - 0.0069 16.4 8.9 0.02 14.9 8.9 1.9 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 PRP76273.1 - 0.019 14.7 15.0 0.047 13.3 3.2 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CodY PF06018.14 PRP76273.1 - 0.019 14.5 0.5 0.55 9.7 0.0 3.2 3 0 0 3 3 3 0 CodY GAF-like domain Paralemmin PF03285.15 PRP76273.1 - 0.1 12.2 3.3 0.21 11.1 3.3 1.4 1 0 0 1 1 1 0 Paralemmin SlyX PF04102.12 PRP76273.1 - 0.13 12.9 3.2 6.1 7.6 1.1 2.9 2 0 0 2 2 2 0 SlyX T3SSipB PF16535.5 PRP76273.1 - 0.15 12.5 2.7 0.23 11.9 1.5 1.9 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF484 PF04340.12 PRP76273.1 - 0.26 11.0 5.8 0.41 10.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF484 FliG_N PF14842.6 PRP76273.1 - 0.4 11.2 3.7 20 5.8 0.6 3.5 3 1 0 3 3 3 0 FliG N-terminal domain TBCA PF02970.16 PRP76273.1 - 0.64 10.4 5.6 1.6 9.1 5.6 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor A Fib_alpha PF08702.10 PRP76273.1 - 2.9 8.1 11.2 0.69 10.1 4.3 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Uso1_p115_C PF04871.13 PRP76273.1 - 5.4 7.4 8.6 7.4 7.0 7.3 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region WD40 PF00400.32 PRP76274.1 - 3.9e-13 49.6 14.3 0.018 15.9 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF4698 PF15769.5 PRP76274.1 - 0.075 12.1 0.0 0.075 12.1 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4698) CHASE8 PF17152.4 PRP76274.1 - 0.18 12.1 0.0 0.74 10.1 0.0 2.0 2 0 0 2 2 2 0 Periplasmic sensor domain Fz PF01392.22 PRP76275.1 - 0.00092 19.8 10.8 0.00092 19.8 10.8 2.0 1 1 1 2 2 2 1 Fz domain WD40 PF00400.32 PRP76276.1 - 3.2e-12 46.7 5.8 0.06 14.3 0.3 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76276.1 - 0.00036 20.8 0.0 2.2 8.7 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BAR PF03114.18 PRP76277.1 - 1.3e-23 83.9 8.0 2.1e-23 83.3 8.0 1.3 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 PRP76277.1 - 1.1e-05 25.3 4.6 1.8e-05 24.6 4.6 1.3 1 0 0 1 1 1 1 BAR domain of APPL family IL11 PF07400.11 PRP76277.1 - 0.018 14.7 2.5 0.27 10.9 0.0 3.0 2 1 1 3 3 3 0 Interleukin 11 Fes1 PF08609.10 PRP76277.1 - 0.6 11.0 0.1 0.6 11.0 0.1 2.7 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 DUF2688 PF10892.8 PRP76278.1 - 0.011 15.2 0.0 0.027 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) ADD_DNMT3 PF17980.1 PRP76278.1 - 0.022 14.7 0.1 0.062 13.3 0.1 1.8 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 TGT PF01702.18 PRP76279.1 - 8.2e-146 485.6 0.0 9.9e-146 485.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Dus PF01207.17 PRP76280.1 - 1.1e-40 139.7 0.0 4.9e-40 137.5 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 PRP76280.1 - 0.002 17.6 0.0 0.0064 16.0 0.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF4336 PF14234.6 PRP76281.1 - 0.00018 20.8 0.0 0.039 13.2 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Pkinase PF00069.25 PRP76282.1 - 1e-73 248.0 0.0 1.2e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76282.1 - 7.6e-34 117.2 0.0 1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP76282.1 - 5.9e-05 22.5 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP76282.1 - 0.017 14.5 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0139 PF03669.13 PRP76283.1 - 0.0012 18.7 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Aldolase_II PF00596.21 PRP76284.1 - 2.6e-46 157.9 0.0 3e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TruD PF01142.18 PRP76285.1 - 2.2e-69 234.3 0.0 5e-67 226.5 0.0 2.9 1 1 2 3 3 3 2 tRNA pseudouridine synthase D (TruD) LTV PF04180.14 PRP76286.1 - 0.0008 19.3 0.0 0.0008 19.3 0.0 4.6 1 1 2 4 4 4 3 Low temperature viability protein Ank_2 PF12796.7 PRP76287.1 - 6.2e-65 215.8 0.0 5.3e-10 39.8 0.0 6.9 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76287.1 - 4.2e-49 164.3 2.0 0.00055 20.4 0.0 12.2 3 1 9 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP76287.1 - 1.7e-34 117.4 0.4 0.1 13.0 0.0 14.0 5 3 11 16 16 16 10 Ankyrin repeats (many copies) Ank PF00023.30 PRP76287.1 - 8.6e-25 86.1 11.9 4.1 8.0 0.1 15.1 15 1 1 16 16 16 6 Ankyrin repeat Ank_3 PF13606.6 PRP76287.1 - 3.2e-19 67.0 0.1 5 8.0 0.0 13.0 14 0 0 14 14 14 3 Ankyrin repeat VWA_3_C PF18571.1 PRP76287.1 - 5.2e-06 26.2 9.3 6.8 6.6 0.0 9.3 11 0 0 11 11 11 1 von Willebrand factor type A C-terminal domain NUMOD3 PF07460.11 PRP76287.1 - 0.005 17.0 0.0 69 3.8 0.0 4.8 4 0 0 4 4 4 0 NUMOD3 motif (2 copies) HyaE PF07449.11 PRP76287.1 - 0.011 15.7 1.3 19 5.2 0.0 4.3 3 2 1 4 4 4 0 Hydrogenase-1 expression protein HyaE DUF1731 PF08338.11 PRP76287.1 - 0.015 15.2 4.3 24 4.8 0.0 6.6 9 0 0 9 9 9 0 Domain of unknown function (DUF1731) HGD-D PF06050.13 PRP76287.1 - 0.082 12.7 0.0 20 4.8 0.0 3.1 1 1 1 3 3 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component AAA PF00004.29 PRP76288.1 - 9.8e-41 139.3 0.6 1.4e-37 129.0 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP76288.1 - 2e-11 43.5 0.0 5.2e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PRP76288.1 - 0.00011 22.5 0.1 0.0013 19.0 0.1 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 PRP76288.1 - 0.00011 21.9 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 PRP76288.1 - 0.00027 21.0 0.3 0.016 15.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PRP76288.1 - 0.00041 20.8 1.0 0.042 14.2 0.1 3.6 3 1 0 4 4 4 1 AAA ATPase domain AAA_5 PF07728.14 PRP76288.1 - 0.00074 19.5 0.0 0.0034 17.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PRP76288.1 - 0.00083 19.5 0.0 0.008 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PRP76288.1 - 0.00096 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 PRP76288.1 - 0.0039 17.7 1.1 0.068 13.7 0.0 3.5 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 PRP76288.1 - 0.004 16.5 0.1 0.01 15.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 PRP76288.1 - 0.0085 16.2 0.0 0.044 13.9 0.0 2.3 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PRP76288.1 - 0.014 14.7 0.2 0.033 13.4 0.1 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 PRP76288.1 - 0.016 14.8 0.1 0.97 9.0 0.2 2.8 2 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 PRP76288.1 - 0.018 14.6 0.1 0.055 13.0 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 PRP76288.1 - 0.026 13.7 0.0 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 PRP76288.1 - 0.031 14.1 2.3 0.034 13.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 PRP76288.1 - 0.047 13.1 0.0 10 5.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein PhoH PF02562.16 PRP76288.1 - 0.059 12.8 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 PRP76288.1 - 0.059 13.1 0.2 0.18 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PRP76288.1 - 0.068 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PRP76288.1 - 0.072 12.8 0.0 0.2 11.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 PRP76288.1 - 0.073 13.5 0.0 0.27 11.6 0.0 2.1 1 0 0 1 1 1 0 RNA helicase NCD2 PF04905.13 PRP76288.1 - 0.1 12.6 0.2 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) TsaE PF02367.17 PRP76288.1 - 0.15 12.0 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pentapeptide PF00805.22 PRP76289.1 - 0.0029 17.2 1.0 0.022 14.4 1.0 2.3 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Glyco_hydro_77 PF02446.17 PRP76291.1 - 2.9e-156 521.0 2.0 2.9e-156 521.0 2.0 1.6 2 0 0 2 2 2 1 4-alpha-glucanotransferase AA_permease PF00324.21 PRP76291.1 - 1.8e-116 389.6 37.3 2.4e-116 389.2 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease CBM_20 PF00686.19 PRP76291.1 - 2.6e-27 94.6 0.1 1.2e-14 54.0 0.0 2.8 2 0 0 2 2 2 2 Starch binding domain AA_permease_2 PF13520.6 PRP76291.1 - 6.7e-26 91.1 40.4 9.4e-26 90.6 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease ATP-synt_C PF00137.21 PRP76292.1 - 7.4e-25 87.1 28.1 3.3e-13 49.8 10.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C G0-G1_switch_2 PF15103.6 PRP76292.1 - 0.62 10.5 0.2 0.62 10.5 0.2 1.7 2 0 0 2 2 2 0 G0/G1 switch protein 2 PIRT PF15099.6 PRP76292.1 - 1.4 8.5 5.0 8.8 5.9 0.5 2.3 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Oxidored_q2 PF00420.24 PRP76292.1 - 1.7 8.3 8.5 0.25 11.0 0.3 2.7 1 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pkinase_Tyr PF07714.17 PRP76294.1 - 1.2e-58 198.4 0.0 2.5e-58 197.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76294.1 - 1.1e-40 139.6 0.0 1.9e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DHHC PF01529.20 PRP76294.1 - 3.6e-33 114.5 11.6 3.6e-33 114.5 11.6 3.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase LRR_4 PF12799.7 PRP76294.1 - 9.7e-22 76.7 83.3 0.0001 22.6 1.6 10.5 5 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP76294.1 - 1.7e-21 75.7 84.5 3.7e-05 23.4 7.1 8.5 5 2 3 8 8 8 8 Leucine rich repeat LRR_6 PF13516.6 PRP76294.1 - 1.1e-09 37.5 52.3 0.38 10.9 0.0 14.7 14 1 1 15 15 15 4 Leucine Rich repeat LRR_9 PF14580.6 PRP76294.1 - 0.0013 18.3 16.5 0.051 13.1 1.1 3.2 1 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 PRP76294.1 - 0.0083 16.5 61.8 0.22 12.2 0.4 14.8 13 2 1 14 14 14 4 Leucine Rich Repeat CBM_15 PF03426.14 PRP76294.1 - 0.097 12.3 0.0 0.097 12.3 0.0 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain (family 15) DUF3082 PF11282.8 PRP76294.1 - 5.9 7.2 7.9 4.2 7.7 4.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3082) Asp_protease_2 PF13650.6 PRP76297.1 - 0.04 14.6 0.0 0.058 14.1 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Homeodomain PF00046.29 PRP76299.1 - 1.1e-15 57.1 8.8 2.9e-15 55.8 8.3 1.8 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 PRP76299.1 - 0.016 14.7 0.2 0.016 14.7 0.2 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez CENP-B_N PF04218.13 PRP76299.1 - 0.018 14.7 0.2 0.3 10.8 0.0 2.3 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain Homeobox_KN PF05920.11 PRP76299.1 - 0.03 14.2 3.2 0.11 12.4 3.2 2.0 1 1 1 2 2 2 0 Homeobox KN domain BrkDBD PF09607.10 PRP76299.1 - 0.036 13.9 0.7 0.068 13.0 0.7 1.6 1 1 0 1 1 1 0 Brinker DNA-binding domain YdaS_antitoxin PF15943.5 PRP76299.1 - 0.088 12.7 0.1 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Ntox27 PF15531.6 PRP76299.1 - 0.12 12.2 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial toxin 27 CENP-K PF11802.8 PRP76300.1 - 0.0025 17.4 9.0 0.0025 17.4 9.0 3.2 1 1 2 3 3 3 1 Centromere-associated protein K YabA PF06156.13 PRP76300.1 - 0.0036 17.9 20.1 0.11 13.1 14.5 3.9 1 1 2 3 3 3 1 Initiation control protein YabA Syntaxin-6_N PF09177.11 PRP76300.1 - 0.0074 16.8 19.7 2.5 8.7 0.0 4.7 1 1 3 4 4 4 2 Syntaxin 6, N-terminal EzrA PF06160.12 PRP76300.1 - 0.0075 14.5 1.2 0.0075 14.5 1.2 2.9 2 2 1 3 3 3 2 Septation ring formation regulator, EzrA Flagellin_N PF00669.20 PRP76300.1 - 0.03 14.4 1.4 0.03 14.4 1.4 3.3 1 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Laminin_II PF06009.12 PRP76300.1 - 0.038 14.0 16.9 1.8 8.6 6.8 3.9 2 2 1 4 4 4 0 Laminin Domain II bZIP_1 PF00170.21 PRP76300.1 - 0.049 13.7 1.7 0.049 13.7 1.7 3.9 5 1 1 6 6 5 0 bZIP transcription factor AAA_13 PF13166.6 PRP76300.1 - 0.07 11.8 23.5 0.041 12.5 18.3 2.0 1 1 1 2 2 2 0 AAA domain DDE_Tnp_IS240 PF13610.6 PRP76300.1 - 0.091 13.0 2.2 0.16 12.1 0.2 2.3 1 1 1 2 2 2 0 DDE domain Spc7 PF08317.11 PRP76300.1 - 0.1 11.5 26.6 0.017 14.0 18.6 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.12 PRP76300.1 - 0.2 11.7 18.1 1 9.4 1.2 4.0 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) FUSC PF04632.12 PRP76300.1 - 0.82 8.1 13.5 0.11 11.0 0.2 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family CSN7a_helixI PF18392.1 PRP76300.1 - 2.4 8.1 5.5 1.8 8.5 0.2 3.0 1 1 1 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain HAUS-augmin3 PF14932.6 PRP76300.1 - 2.6 7.5 24.6 4.9 6.6 20.7 2.8 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 MitMem_reg PF13012.6 PRP76300.1 - 7.8 7.0 15.8 1e+03 0.1 15.7 3.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function GAS PF13851.6 PRP76300.1 - 8.7 5.6 31.8 0.28 10.5 12.9 3.6 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding adh_short PF00106.25 PRP76301.1 - 2.1e-29 102.4 2.1 9.2e-29 100.3 2.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP76301.1 - 1.4e-17 64.1 0.8 6.1e-17 62.0 0.8 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP76301.1 - 1.5e-07 31.5 0.1 2.4e-07 30.8 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP76301.1 - 0.00069 19.1 0.1 0.0064 16.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 PRP76301.1 - 0.0039 17.3 0.5 0.0094 16.0 0.3 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PRP76301.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 PRP76301.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 PRP76301.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DEAD PF00270.29 PRP76302.1 - 8.2e-47 159.2 0.0 1.1e-45 155.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP76302.1 - 5e-31 107.3 0.1 1e-30 106.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 PRP76302.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Methyltransf_17 PF12692.7 PRP76302.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase ResIII PF04851.15 PRP76302.1 - 0.13 12.3 0.0 15 5.6 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Epsilon_antitox PF08998.11 PRP76304.1 - 0.17 12.2 0.0 6.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial epsilon antitoxin D123 PF07065.14 PRP76306.1 - 1.3e-76 257.7 0.9 4.1e-75 252.8 0.9 2.0 1 1 0 1 1 1 1 D123 GAS PF13851.6 PRP76308.1 - 0.0038 16.6 7.0 0.0038 16.6 7.0 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF5442 PF17514.2 PRP76308.1 - 0.23 11.7 2.4 4.6 7.5 0.0 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5442) DUF2859 PF11072.8 PRP76309.1 - 0.047 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) cNMP_binding PF00027.29 PRP76310.1 - 7.6e-09 35.5 0.1 4.7e-06 26.6 0.1 2.4 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 PRP76310.1 - 0.0016 18.4 1.3 0.0054 16.7 1.3 2.0 1 0 0 1 1 1 1 Ion channel WH2 PF02205.20 PRP76311.1 - 4.1e-06 26.4 1.6 7.9e-06 25.5 1.6 1.5 1 0 0 1 1 1 1 WH2 motif Pkinase_Tyr PF07714.17 PRP76311.1 - 0.00096 18.5 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76311.1 - 0.0062 15.9 0.5 0.069 12.5 0.1 2.6 3 1 1 4 4 4 1 Protein kinase domain DEC-1_N PF04625.13 PRP76311.1 - 0.3 10.0 18.9 0.58 9.1 18.9 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Shisa PF13908.6 PRP76311.1 - 3.8 7.7 4.6 37 4.5 0.0 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ribosomal_60s PF00428.19 PRP76311.1 - 5.1 7.8 5.7 11 6.7 4.6 2.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein Mob_synth_C PF06463.13 PRP76312.1 - 1.3e-39 135.1 0.0 3.7e-39 133.6 0.0 1.8 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 PRP76312.1 - 2e-30 106.4 0.9 8.7e-30 104.3 0.2 2.5 2 0 0 2 2 2 1 Radical SAM superfamily cNMP_binding PF00027.29 PRP76312.1 - 5.8e-28 96.8 0.2 3.5e-13 49.4 0.0 3.1 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain RasGEF PF00617.19 PRP76312.1 - 1.6e-21 77.3 0.0 6.2e-21 75.4 0.0 2.1 1 0 0 1 1 1 1 RasGEF domain PLDc PF00614.22 PRP76312.1 - 3.7e-20 71.2 2.3 5.5e-11 42.2 0.7 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PRP76312.1 - 2.3e-18 66.4 0.1 3.8e-09 36.5 0.0 2.9 2 1 0 2 2 2 2 PLD-like domain RasGEF_N PF00618.20 PRP76312.1 - 4.4e-09 36.5 0.0 1.3e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Fer4_12 PF13353.6 PRP76312.1 - 1.8e-07 31.5 0.0 5.5e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain GRAM PF02893.20 PRP76312.1 - 8.7e-05 22.4 0.2 0.0003 20.7 0.2 1.9 1 0 0 1 1 1 1 GRAM domain Fer4_14 PF13394.6 PRP76312.1 - 0.0002 21.5 0.7 0.0014 18.7 0.0 2.7 3 0 0 3 3 3 1 4Fe-4S single cluster domain PH PF00169.29 PRP76312.1 - 0.11 13.0 0.0 0.47 11.0 0.0 2.2 1 0 0 1 1 1 0 PH domain Zot PF05707.12 PRP76313.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 PRP76313.1 - 0.19 12.1 0.0 1.8 8.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain Dmrt1 PF12374.8 PRP76316.1 - 0.056 13.9 1.5 0.089 13.2 1.5 1.3 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 SF1-HH PF16275.5 PRP76317.1 - 0.037 14.4 0.0 0.054 13.8 0.0 1.2 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain zf-U11-48K PF05253.12 PRP76318.1 - 0.02 14.8 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger zf-TRAF PF02176.18 PRP76318.1 - 0.029 15.0 0.0 0.074 13.7 0.0 1.7 1 0 0 1 1 1 0 TRAF-type zinc finger Hid1 PF12722.7 PRP76320.1 - 0.42 8.7 7.0 0.48 8.5 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 PRP76320.1 - 1.7 6.8 8.5 2 6.6 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 PRP76320.1 - 3.4 6.3 9.8 4.2 6.0 9.8 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 PRP76320.1 - 5.3 5.5 11.2 6.1 5.3 11.2 1.1 1 0 0 1 1 1 0 Macoilin family PWWP PF00855.17 PRP76321.1 - 0.13 12.7 0.1 0.16 12.3 0.1 1.3 1 1 0 1 1 1 0 PWWP domain U3snoRNP10 PF12397.8 PRP76324.1 - 0.11 12.9 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 EFG_IV PF03764.18 PRP76325.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G, domain IV SKG6 PF08693.10 PRP76325.1 - 0.87 9.1 4.3 1.6 8.2 4.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3586 PF12131.8 PRP76327.1 - 0.022 15.0 4.7 0.022 15.0 4.7 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3586) RNA_pol_Rpb1_2 PF00623.20 PRP76335.1 - 5.5e-11 43.0 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PRP76335.1 - 3.2e-10 40.2 0.1 1.3e-05 25.2 0.0 2.6 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_5 PF04998.17 PRP76337.1 - 9.7e-52 176.0 0.0 1.2e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 PRP76337.1 - 9.5e-21 74.5 0.2 4.3e-15 56.0 0.0 2.3 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 PRP76337.1 - 3.9e-10 39.8 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_5 PF04998.17 PRP76342.1 - 2.8e-51 174.5 0.1 4.9e-51 173.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_7 PF04990.12 PRP76342.1 - 1.9e-31 108.8 0.9 4.1e-31 107.8 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 SNF2_N PF00176.23 PRP76342.1 - 9.6e-11 41.0 0.0 1.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain RNA_pol_Rpb1_2 PF00623.20 PRP76343.1 - 4.4e-47 160.4 1.9 8.5e-46 156.2 1.9 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 PRP76343.1 - 6.8e-23 81.5 0.0 1.6e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.17 PRP76343.1 - 1.5e-07 31.3 1.3 0.00044 20.2 0.1 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 PRP76343.1 - 0.00076 19.4 0.1 0.017 15.1 0.0 2.1 1 1 1 2 2 2 1 RNA polymerase Rpb1, domain 3 Glyco_hydro_18 PF00704.28 PRP76345.1 - 6.8e-15 55.6 4.1 9.6e-15 55.1 4.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP76345.1 - 4.2e-10 39.9 43.0 7.3e-06 26.4 12.5 3.3 3 0 0 3 3 3 2 Chitin recognition protein Apt1 PF10351.9 PRP76345.1 - 0.13 11.0 2.9 0.18 10.6 2.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain IlvGEDA_leader PF08046.11 PRP76345.1 - 1.6 8.3 11.7 0.036 13.5 1.5 2.3 2 0 0 2 2 2 0 IlvGEDA operon leader peptide DCP2 PF05026.13 PRP76347.1 - 6.8e-29 100.0 0.2 1.3e-28 99.1 0.2 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 PRP76347.1 - 1.4e-15 57.4 0.0 2.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Nucleoporin_FG PF13634.6 PRP76348.1 - 1.1e-34 119.1 71.1 0.00026 21.8 7.9 9.7 3 2 2 5 5 5 3 Nucleoporin FG repeat region tRNA-synt_1e PF01406.19 PRP76349.1 - 3.5e-127 423.9 0.2 3.5e-127 423.9 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PRP76349.1 - 3.1e-11 42.7 2.9 7.4e-06 25.0 0.6 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PRP76349.1 - 0.00066 18.1 4.0 0.0027 16.0 0.0 3.0 3 1 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 PRP76349.1 - 0.006 15.5 1.3 0.97 8.3 0.1 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 PRP76349.1 - 0.011 14.7 0.4 0.079 11.8 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.11 PRP76349.1 - 0.1 13.1 3.8 0.28 11.7 0.0 3.0 3 0 0 3 3 3 0 DALR domain TPT PF03151.16 PRP76350.1 - 3.8e-05 23.2 15.7 5.9e-05 22.6 15.7 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PRP76350.1 - 0.00014 22.0 11.0 0.00014 22.0 11.0 2.5 2 0 0 2 2 2 1 EamA-like transporter family Proteasome PF00227.26 PRP76351.1 - 1.2e-45 155.4 0.1 3e-45 154.1 0.0 1.6 1 1 1 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 PRP76351.1 - 5.1e-11 42.0 0.1 8.5e-11 41.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SUZ PF12752.7 PRP76352.1 - 0.099 13.4 0.3 0.19 12.5 0.3 1.5 1 0 0 1 1 1 0 SUZ domain zf-BED PF02892.15 PRP76353.1 - 0.64 10.1 4.0 0.39 10.8 0.5 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.6 PRP76353.1 - 8.1 7.6 11.1 0.88 10.6 2.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger AIF_C PF14721.6 PRP76354.1 - 0.066 13.6 1.1 0.14 12.5 0.2 2.1 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PAS_5 PF07310.13 PRP76356.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 PAS domain LRR_6 PF13516.6 PRP76357.1 - 0.0092 16.0 0.1 0.039 14.0 0.0 2.0 2 0 0 2 2 2 1 Leucine Rich repeat WD40 PF00400.32 PRP76358.1 - 3.7e-29 100.4 23.2 4e-06 27.5 1.0 8.2 8 1 1 9 9 8 6 WD domain, G-beta repeat Hira PF07569.11 PRP76358.1 - 5.7e-24 85.1 3.5 1e-13 51.6 1.2 3.1 2 1 1 3 3 3 2 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 PRP76358.1 - 1.6e-17 63.6 0.1 9.9e-05 22.6 0.1 6.6 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP76358.1 - 2.3e-07 30.9 0.2 0.55 10.1 0.0 4.1 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PRP76358.1 - 0.00043 19.7 0.0 0.48 9.7 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain PD40 PF07676.12 PRP76358.1 - 0.0013 18.6 3.1 1.2 9.2 0.1 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 PRP76358.1 - 0.018 14.0 0.8 0.33 9.9 0.0 2.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 PRP76358.1 - 0.037 13.9 0.3 0.16 11.8 0.3 2.3 1 0 0 1 1 1 0 HIRA B motif DPPIV_N PF00930.21 PRP76358.1 - 0.051 12.3 0.8 6.5 5.4 0.0 4.0 4 1 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Uteroglobin PF01099.17 PRP76358.1 - 0.36 11.2 2.2 0.28 11.5 0.1 1.9 2 0 0 2 2 2 0 Uteroglobin family Nucleo_P87 PF07267.11 PRP76358.1 - 0.56 9.0 14.0 0.97 8.2 14.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Vfa1 PF08432.10 PRP76358.1 - 1.3 9.3 14.4 0.4 11.0 10.0 2.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 SWI-SNF_Ssr4 PF08549.10 PRP76358.1 - 1.9 7.0 11.0 2.8 6.5 11.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF1764 PF08576.10 PRP76359.1 - 8.5e-17 61.9 16.7 1.1e-15 58.4 16.7 2.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) ORC6 PF05460.13 PRP76359.1 - 0.3 10.3 9.7 0.34 10.1 9.7 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hamartin PF04388.12 PRP76359.1 - 1.3 7.6 5.5 1.3 7.6 5.5 1.0 1 0 0 1 1 1 0 Hamartin protein Gelsolin PF00626.22 PRP76360.1 - 2.4e-33 113.8 12.8 5.2e-07 29.5 0.0 8.1 8 0 0 8 8 8 5 Gelsolin repeat Pkinase_Tyr PF07714.17 PRP76360.1 - 6.2e-15 55.2 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP76360.1 - 6.5e-12 45.9 10.2 1e-05 26.0 0.4 3.7 2 1 0 2 2 2 2 PH domain Pkinase PF00069.25 PRP76360.1 - 1.2e-10 41.2 0.1 1.2e-10 41.2 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain PH_9 PF15410.6 PRP76360.1 - 0.0011 19.3 2.6 0.011 16.1 0.5 3.3 2 1 1 3 3 3 1 Pleckstrin homology domain C1_1 PF00130.22 PRP76360.1 - 0.032 14.1 5.1 0.061 13.2 5.1 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 PRP76360.1 - 0.049 14.0 6.7 0.11 12.9 6.7 1.6 1 0 0 1 1 1 0 C1 domain RRF PF01765.19 PRP76361.1 - 1.1e-40 139.2 6.0 2.1e-40 138.4 6.0 1.4 1 0 0 1 1 1 1 Ribosome recycling factor ATP-synt_B PF00430.18 PRP76361.1 - 1.1 9.3 7.4 2 8.5 7.4 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Kinesin PF00225.23 PRP76362.1 - 1.4e-99 333.2 3.5 1.4e-99 333.2 3.5 1.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP76362.1 - 2.7e-43 147.5 0.0 7.4e-43 146.0 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_24 PF13479.6 PRP76362.1 - 0.0011 18.7 5.5 0.15 11.8 0.2 3.3 3 0 0 3 3 3 2 AAA domain PKcGMP_CC PF16808.5 PRP76362.1 - 4.6 7.2 10.4 20 5.1 0.1 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SRP68 PF16969.5 PRP76363.1 - 7.2e-13 48.4 0.2 8.8e-13 48.1 0.2 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Nuc_N PF14448.6 PRP76364.1 - 0.17 11.7 0.2 0.28 11.1 0.1 1.4 1 1 0 1 1 1 0 Nuclease N terminal DUF4481 PF14800.6 PRP76367.1 - 0.0071 15.8 0.1 0.0073 15.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) adh_short PF00106.25 PRP76370.1 - 4.3e-07 29.6 0.0 1.1e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 PRP76370.1 - 3.3e-06 27.1 0.0 8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 PRP76370.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Melibiase_2 PF16499.5 PRP76371.1 - 1.6e-43 148.9 7.9 3.1e-43 148.0 7.9 1.4 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase PF02065.18 PRP76371.1 - 8.2e-09 34.9 0.1 1.7e-08 33.9 0.0 1.5 2 0 0 2 2 2 1 Melibiase Peptidase_M3 PF01432.20 PRP76373.1 - 1.3e-89 301.6 0.0 1.9e-89 301.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 PRP76373.1 - 0.12 12.1 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Pkinase PF00069.25 PRP76376.1 - 3.4e-49 167.6 0.0 4.9e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76376.1 - 2.6e-31 108.9 0.0 4.2e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_3 PF13415.6 PRP76376.1 - 4.2e-22 77.9 11.5 8e-08 32.4 0.3 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 PRP76376.1 - 2.3e-20 72.3 8.9 7.4e-07 29.1 0.1 5.9 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP76376.1 - 3.3e-15 55.7 3.5 0.00012 22.3 0.0 6.2 5 1 1 6 6 6 2 Kelch motif Kinase-like PF14531.6 PRP76376.1 - 5e-14 52.3 0.2 1.6e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kelch_1 PF01344.25 PRP76376.1 - 1.1e-13 50.5 1.7 5.2e-07 29.2 0.0 5.3 7 0 0 7 7 7 2 Kelch motif Kelch_5 PF13854.6 PRP76376.1 - 2.6e-11 43.2 6.5 9.3e-05 22.3 0.0 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 PRP76376.1 - 4.7e-11 42.2 4.5 0.00015 21.6 0.0 5.9 6 1 0 6 6 6 2 Kelch motif Kdo PF06293.14 PRP76376.1 - 0.0093 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pro_dh PF01619.18 PRP76377.1 - 7.9e-80 268.5 0.0 1.2e-79 268.0 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Late_protein_L2 PF00513.18 PRP76378.1 - 2.4 7.1 12.6 3.5 6.5 12.6 1.1 1 0 0 1 1 1 0 Late Protein L2 M20_dimer PF07687.14 PRP76380.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase dimerisation domain Ig_mannosidase PF17753.1 PRP76382.1 - 3.2e-11 42.8 0.0 7.7e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 PRP76382.1 - 1.1e-10 42.1 0.0 2.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 PRP76382.1 - 1.4e-07 31.6 0.0 3.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 PRP76382.1 - 0.12 11.5 1.1 0.99 8.4 0.7 2.3 2 1 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain DCAF15_WD40 PF14939.6 PRP76383.1 - 6.8e-27 94.5 0.0 3.9e-19 69.2 0.0 2.2 2 0 0 2 2 2 2 DDB1-and CUL4-substrate receptor 15, WD repeat Hormone_4 PF00220.17 PRP76384.1 - 0.48 10.5 2.6 0.77 9.9 2.6 1.3 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Glyco_transf_90 PF05686.12 PRP76387.1 - 1.7e-10 40.4 3.7 8.2e-08 31.5 1.2 3.6 3 1 0 3 3 3 2 Glycosyl transferase family 90 Meckelin PF09773.9 PRP76388.1 - 1.8e-190 635.0 0.5 1.8e-190 635.0 0.5 2.0 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) HhH-GPD PF00730.25 PRP76389.1 - 2.9e-13 50.2 0.0 4.6e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.6 PRP76389.1 - 0.031 14.8 0.3 0.29 11.7 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4473) Vps54 PF07928.12 PRP76391.1 - 3.5e-41 140.8 2.2 3.5e-41 140.8 2.2 2.4 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 PRP76391.1 - 9e-14 51.4 3.8 9e-14 51.4 3.8 2.5 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex BLOC1_2 PF10046.9 PRP76391.1 - 0.16 12.3 4.0 0.11 12.8 0.3 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ank_2 PF12796.7 PRP76393.1 - 1.7e-19 70.2 0.1 4e-08 33.7 0.0 3.9 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76393.1 - 1.3e-12 47.9 3.8 9.8e-05 22.8 0.1 6.3 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76393.1 - 2.4e-10 39.8 1.5 0.49 11.1 0.0 6.7 8 1 1 9 9 9 4 Ankyrin repeat Ank PF00023.30 PRP76393.1 - 4e-10 39.7 5.1 3.6 8.2 0.0 8.2 8 1 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 PRP76393.1 - 2.2e-06 27.8 6.2 0.13 12.6 0.0 6.0 3 2 5 8 8 8 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP76394.1 - 0.051 14.2 0.0 0.062 13.9 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DnaB_2 PF07261.11 PRP76394.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.7 1 1 0 1 1 1 0 Replication initiation and membrane attachment BCA_ABC_TP_C PF12399.8 PRP76394.1 - 1 9.4 5.3 3.6 7.6 0.5 3.2 4 0 0 4 4 4 0 Branched-chain amino acid ATP-binding cassette transporter F-box-like PF12937.7 PRP76395.1 - 0.0076 16.1 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP76395.1 - 0.049 13.5 0.3 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 F-box domain DNA_binding_1 PF01035.20 PRP76396.1 - 1.3e-28 99.0 0.0 1.7e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Aminotran_5 PF00266.19 PRP76397.1 - 1.1e-05 24.6 0.0 6.1e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V TPR_1 PF00515.28 PRP76398.1 - 7.5e-64 209.1 23.7 7.1e-08 32.0 0.3 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 PRP76398.1 - 4.5e-52 170.0 21.3 1.9e-05 24.4 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 PRP76398.1 - 2.7e-35 120.1 17.6 3.7e-21 74.8 1.6 3.0 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 PRP76398.1 - 7.9e-32 108.7 26.6 2e-06 27.4 0.1 9.5 4 3 5 9 9 9 9 TPR repeat TPR_8 PF13181.6 PRP76398.1 - 3.7e-31 104.7 23.6 0.00021 21.3 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 PRP76398.1 - 1.1e-26 92.9 19.9 4.6e-11 42.9 0.2 7.2 3 3 3 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.6 PRP76398.1 - 1.5e-22 79.9 2.1 0.00035 21.2 0.1 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 PRP76398.1 - 6.1e-18 64.0 0.2 0.22 12.5 0.0 8.4 3 3 6 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP76398.1 - 3.1e-16 59.6 7.2 0.00055 20.4 0.3 6.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 PRP76398.1 - 5.8e-16 57.8 13.8 0.0086 15.9 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 PRP76398.1 - 9.1e-16 56.7 15.9 0.021 14.8 0.0 9.2 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 PRP76398.1 - 3.3e-14 52.1 18.8 0.0051 17.1 0.4 8.8 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 PRP76398.1 - 7e-12 45.3 0.0 0.0019 18.3 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP76398.1 - 9.5e-10 38.4 16.0 0.011 15.7 0.1 6.7 7 1 1 8 8 7 3 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 PRP76398.1 - 7e-09 35.0 4.0 0.76 9.3 0.1 7.1 7 0 0 7 7 7 1 SHNi-TPR ANAPC3 PF12895.7 PRP76398.1 - 3.7e-08 33.5 18.2 0.00035 20.7 0.6 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 PRP76398.1 - 2.8e-06 26.5 12.6 0.016 14.2 0.9 3.4 2 1 1 3 3 3 3 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 PRP76398.1 - 1.3e-05 25.4 10.0 0.35 11.2 0.0 5.4 4 3 2 6 6 6 2 Tetratricopeptide repeat DUF3856 PF12968.7 PRP76398.1 - 0.0001 22.4 5.7 2.5 8.2 0.5 5.6 4 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 PRP76398.1 - 0.00029 21.3 17.8 12 6.8 0.0 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.18 PRP76398.1 - 0.00033 20.7 22.8 4.6 7.4 0.1 7.8 5 3 2 7 7 7 1 MIT (microtubule interacting and transport) domain BTAD PF03704.17 PRP76398.1 - 0.0046 17.4 8.1 18 5.8 0.1 5.1 2 2 2 4 4 4 0 Bacterial transcriptional activator domain DS PF01916.17 PRP76398.1 - 0.0095 15.2 0.6 0.059 12.6 0.1 2.2 1 1 1 2 2 2 1 Deoxyhypusine synthase ATG16 PF08614.11 PRP76398.1 - 0.017 15.4 0.4 0.017 15.4 0.4 3.0 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) TPR_3 PF07720.12 PRP76398.1 - 0.025 14.5 17.2 8.2 6.5 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat SPO22 PF08631.10 PRP76398.1 - 0.026 14.0 11.3 0.97 8.9 0.2 5.1 4 1 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like U83 PF17465.2 PRP76398.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Chemokine-like protein, HHV-6 U83 gene product HsbA PF12296.8 PRP76398.1 - 0.25 11.8 2.2 3.5 8.1 0.0 3.7 5 0 0 5 5 5 0 Hydrophobic surface binding protein A Bul1_C PF04426.12 PRP76398.1 - 2.2 7.6 7.5 1.7 8.0 0.3 2.7 2 1 1 3 3 3 0 Bul1 C terminus EF-hand_7 PF13499.6 PRP76399.1 - 1.5e-09 38.2 0.2 2.3e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP76399.1 - 3.1e-08 32.6 2.2 7.9e-07 28.2 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PRP76399.1 - 2e-07 30.4 2.4 2.6e-07 30.0 0.5 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 PRP76399.1 - 1.6e-05 24.6 0.6 0.0006 19.6 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP76399.1 - 0.00022 20.5 0.0 0.00048 19.5 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_9 PF14658.6 PRP76399.1 - 0.059 13.7 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain Erf4 PF10256.9 PRP76400.1 - 1.2e-16 60.8 0.3 1.5e-16 60.5 0.3 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family RPEL PF02755.15 PRP76400.1 - 2.1 8.1 5.7 9.5 6.1 0.3 2.3 2 0 0 2 2 2 0 RPEL repeat adh_short PF00106.25 PRP76401.1 - 7e-16 58.3 0.0 2.1e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP76401.1 - 4.8e-11 42.7 0.0 7.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP76401.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain PsbY PF06298.11 PRP76401.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) DUF99 PF01949.16 PRP76401.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 RRM_1 PF00076.22 PRP76402.1 - 2.4e-54 181.0 0.7 1.3e-16 60.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP76402.1 - 9.2e-07 28.9 0.0 0.04 14.0 0.0 4.6 4 0 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 PRP76402.1 - 7.6e-06 25.7 1.5 0.022 14.6 0.0 4.4 4 1 0 4 4 4 1 Occluded RNA-recognition motif CDC45 PF02724.14 PRP76402.1 - 9.8e-05 20.8 13.4 9.8e-05 20.8 13.4 3.4 3 1 1 4 4 4 1 CDC45-like protein DNA_pol_phi PF04931.13 PRP76402.1 - 0.0005 18.3 24.4 0.0005 18.3 24.4 3.0 2 1 1 3 3 3 1 DNA polymerase phi Prothymosin PF03247.14 PRP76402.1 - 0.0015 18.9 40.4 0.0015 18.9 40.4 5.3 4 1 1 5 5 5 1 Prothymosin/parathymosin family CDC27 PF09507.10 PRP76402.1 - 0.0034 16.8 41.8 0.0034 16.8 41.8 3.1 2 1 0 3 3 3 1 DNA polymerase subunit Cdc27 PTPRCAP PF15713.5 PRP76402.1 - 0.015 15.6 24.0 0.015 15.6 24.0 4.2 3 1 1 4 4 4 0 Protein tyrosine phosphatase receptor type C-associated RRM_2 PF04059.12 PRP76402.1 - 0.032 14.5 0.3 0.76 10.0 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif 2 Nup35_RRM_2 PF14605.6 PRP76402.1 - 0.038 14.0 1.4 9.4 6.3 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 PRP76403.1 - 4.5e-67 226.2 0.0 6.6e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76403.1 - 5.6e-30 104.5 0.1 1.8e-29 102.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP76403.1 - 4.5e-07 29.5 0.0 8.3e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Sld5 PF05916.11 PRP76403.1 - 4.9e-07 30.2 0.1 1.6e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 GINS complex protein FTA2 PF13095.6 PRP76403.1 - 0.0017 18.0 0.1 0.0029 17.2 0.1 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PRP76403.1 - 0.0019 17.6 0.4 0.0059 16.0 0.4 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP76403.1 - 0.023 14.3 0.2 0.053 13.1 0.2 1.5 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 PRP76404.1 - 1.6e-24 85.7 10.4 0.0028 18.5 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76404.1 - 0.0017 18.6 0.4 4.4 7.7 0.0 4.1 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP76404.1 - 0.11 12.4 0.0 0.7 9.7 0.0 2.0 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A NIBRIN_BRCT_II PF16508.5 PRP76404.1 - 0.14 12.5 0.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein UCH PF00443.29 PRP76405.1 - 4e-43 147.8 1.4 4e-43 147.8 0.0 1.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP76405.1 - 2.9e-16 60.0 0.1 9.2e-16 58.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF5620 PF18522.1 PRP76407.1 - 0.14 12.6 1.6 0.26 11.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5620) WD40 PF00400.32 PRP76408.1 - 5.1e-23 80.9 10.8 2.5e-07 31.3 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76408.1 - 4.9e-10 39.6 0.1 0.00045 20.5 0.0 4.2 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP76408.1 - 0.00017 20.4 0.4 0.11 11.2 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PRP76408.1 - 0.00081 18.4 0.1 0.0022 17.0 0.0 1.7 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RasGEF PF00617.19 PRP76409.1 - 7.3e-52 176.1 3.5 4.7e-51 173.5 0.2 3.4 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 PRP76409.1 - 2.2e-18 66.4 0.2 1e-16 61.0 0.0 3.7 3 0 0 3 3 3 1 RasGEF N-terminal motif FANCI_HD1 PF14679.6 PRP76409.1 - 0.016 15.1 0.1 0.072 13.1 0.1 2.2 1 0 0 1 1 1 0 FANCI helical domain 1 APG6 PF04111.12 PRP76409.1 - 0.024 14.6 0.1 0.07 13.1 0.1 1.8 1 0 0 1 1 1 0 Apg6 BARA domain DUF3802 PF12290.8 PRP76409.1 - 2.2 8.8 6.1 2 8.9 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) Ank_4 PF13637.6 PRP76411.1 - 0.0094 16.5 1.1 3e+02 2.1 0.0 6.0 6 1 2 8 8 8 0 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP76411.1 - 0.055 13.4 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 F-box-like RasGEF PF00617.19 PRP76413.1 - 7.3e-52 176.1 3.5 4.7e-51 173.5 0.2 3.4 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 PRP76413.1 - 2.2e-18 66.4 0.2 1e-16 61.0 0.0 3.7 3 0 0 3 3 3 1 RasGEF N-terminal motif FANCI_HD1 PF14679.6 PRP76413.1 - 0.016 15.1 0.1 0.072 13.1 0.1 2.2 1 0 0 1 1 1 0 FANCI helical domain 1 APG6 PF04111.12 PRP76413.1 - 0.024 14.6 0.1 0.07 13.1 0.1 1.8 1 0 0 1 1 1 0 Apg6 BARA domain DUF3802 PF12290.8 PRP76413.1 - 2.2 8.8 6.1 2 8.9 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) WD40 PF00400.32 PRP76414.1 - 5.1e-23 80.9 10.8 2.5e-07 31.3 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76414.1 - 4.9e-10 39.6 0.1 0.00045 20.5 0.0 4.2 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP76414.1 - 0.00017 20.4 0.4 0.11 11.2 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PRP76414.1 - 0.00081 18.4 0.1 0.0022 17.0 0.0 1.7 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5620 PF18522.1 PRP76415.1 - 0.14 12.6 1.6 0.26 11.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5620) Hydrolase_6 PF13344.6 PRP76416.1 - 6.3e-15 55.1 0.0 9.6e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 PRP76417.1 - 6.6e-25 87.5 0.0 8.1e-08 32.7 0.0 3.5 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76417.1 - 2.2e-14 53.6 1.9 0.003 18.1 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76417.1 - 2.9e-12 45.6 0.3 0.38 11.5 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 PRP76417.1 - 4e-07 30.2 0.3 0.25 11.8 0.0 5.7 5 2 2 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 PRP76417.1 - 5.1e-07 29.9 0.1 0.11 12.8 0.0 4.9 1 1 4 5 5 5 2 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP76417.1 - 0.0014 18.5 0.1 0.0044 16.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like VWA_3_C PF18571.1 PRP76417.1 - 0.076 12.9 0.0 0.87 9.5 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain WSD PF15613.6 PRP76419.1 - 1.9e-15 57.1 0.9 1.8e-14 54.0 0.1 2.9 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 PRP76419.1 - 1.8e-11 43.8 8.7 2e-11 43.6 7.5 1.8 2 0 0 2 2 2 1 PHD-finger WHIM1 PF15612.6 PRP76419.1 - 0.0026 17.2 0.0 0.007 15.9 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DNMT1-RFD PF12047.8 PRP76419.1 - 0.011 15.8 0.0 0.011 15.8 0.0 2.5 2 1 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain PHD_2 PF13831.6 PRP76419.1 - 0.015 14.9 1.4 0.035 13.7 1.4 1.7 1 0 0 1 1 1 0 PHD-finger CDC24_OB3 PF17244.2 PRP76419.1 - 0.083 12.6 0.5 0.46 10.2 0.3 2.2 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 AT_hook PF02178.19 PRP76419.1 - 0.42 10.6 7.2 2.3 8.4 7.2 2.4 1 0 0 1 1 1 0 AT hook motif Dabb PF07876.12 PRP76421.1 - 5.6e-17 62.2 0.1 4.5e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Stress responsive A/B Barrel Domain CHORD PF04968.12 PRP76421.1 - 0.0011 19.7 2.0 1.4 9.7 0.2 2.5 2 0 0 2 2 2 2 CHORD Sar8_2 PF03058.14 PRP76421.1 - 0.023 15.2 0.8 0.057 14.0 0.2 1.9 2 1 0 2 2 2 0 Sar8.2 family GatD_N PF18195.1 PRP76421.1 - 0.068 12.5 0.1 11 5.4 0.0 2.5 2 0 0 2 2 2 0 GatD N-terminal domain MA3 PF02847.17 PRP76421.1 - 0.1 12.6 0.0 5.6 7.0 0.0 2.3 2 0 0 2 2 2 0 MA3 domain zf-RVT PF13966.6 PRP76423.1 - 0.0011 19.7 0.1 0.0025 18.5 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RecR PF02132.15 PRP76423.1 - 0.13 11.8 0.6 0.24 11.0 0.6 1.4 1 0 0 1 1 1 0 RecR protein zf-RVT PF13966.6 PRP76425.1 - 0.0032 18.1 2.6 0.0032 18.1 2.6 2.4 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase Pkinase PF00069.25 PRP76426.1 - 1.8e-77 260.3 0.0 2.9e-77 259.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76426.1 - 1.6e-44 152.2 0.0 3e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP76426.1 - 6.5e-09 35.5 0.0 6.3e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Arm PF00514.23 PRP76426.1 - 4.7e-08 32.8 0.6 0.0035 17.3 0.0 5.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Pkinase_fungal PF17667.1 PRP76426.1 - 0.00029 19.7 0.0 0.00051 18.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase HEAT_2 PF13646.6 PRP76426.1 - 0.00033 21.0 0.0 0.013 15.9 0.0 3.4 2 1 2 4 4 3 2 HEAT repeats HEAT PF02985.22 PRP76426.1 - 0.00061 19.8 0.0 11 6.6 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat FTA2 PF13095.6 PRP76426.1 - 0.0026 17.4 0.2 0.015 14.9 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PRP76426.1 - 0.0047 16.3 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP76426.1 - 0.0064 15.5 1.3 0.012 14.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PRP76426.1 - 0.0069 16.3 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 PRP76426.1 - 0.021 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HSR PF03172.13 PRP76426.1 - 0.055 13.6 0.0 7.5 6.8 0.0 3.3 3 0 0 3 3 3 0 HSR domain RIO1 PF01163.22 PRP76426.1 - 0.06 12.9 0.1 0.14 11.7 0.1 1.6 1 1 0 1 1 1 0 RIO1 family DUF3361 PF11841.8 PRP76426.1 - 2.6 8.0 8.3 70 3.3 0.0 5.4 6 1 0 6 6 6 0 Domain of unknown function (DUF3361) ArsA_ATPase PF02374.15 PRP76427.1 - 5.6e-112 373.9 0.0 7.9e-112 373.4 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 PRP76427.1 - 4.7e-12 46.2 2.1 2.3e-11 44.0 0.0 2.9 4 1 0 4 4 4 1 AAA domain CbiA PF01656.23 PRP76427.1 - 4.1e-11 43.0 0.1 5.7e-10 39.3 0.1 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 PRP76427.1 - 1.5e-05 24.6 0.4 0.00059 19.4 0.3 2.7 2 1 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 PRP76427.1 - 2.6e-05 23.8 0.0 5.3e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 PRP76427.1 - 5.9e-05 22.8 0.0 0.005 16.5 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 PRP76427.1 - 9.6e-05 21.9 0.0 0.0003 20.3 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 PRP76427.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP76427.1 - 0.043 13.1 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.22 PRP76427.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 PRP76427.1 - 0.24 11.8 1.9 4.2 7.8 0.4 3.0 3 1 0 3 3 3 0 RNA helicase Nup192 PF11894.8 PRP76428.1 - 9e-114 381.2 32.1 2.8e-102 343.1 16.1 2.7 2 1 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 FYRC PF05965.14 PRP76429.1 - 2.8e-13 49.8 0.0 1.3e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 PRP76429.1 - 1.2e-08 34.7 1.3 2.5e-08 33.7 1.3 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus DUF716 PF04819.12 PRP76429.1 - 0.016 14.8 0.4 0.016 14.8 0.4 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF716) UxuA PF03786.13 PRP76430.1 - 0.041 12.7 0.0 0.73 8.6 0.0 2.0 2 0 0 2 2 2 0 D-mannonate dehydratase (UxuA) Inovirus_Gp2 PF11726.8 PRP76430.1 - 0.09 12.7 0.1 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 Inovirus Gp2 DUF2202 PF09968.9 PRP76430.1 - 0.11 12.3 0.1 0.38 10.6 0.2 1.7 1 1 1 2 2 2 0 Uncharacterized protein domain (DUF2202) DUF2931 PF11153.8 PRP76430.1 - 0.12 12.1 0.0 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) Inos-1-P_synth PF01658.17 PRP76431.1 - 0.037 14.3 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Prosystemin PF07376.11 PRP76432.1 - 0.058 12.9 5.6 0.066 12.7 5.1 1.3 1 1 0 1 1 1 0 Prosystemin LIM PF00412.22 PRP76435.1 - 8.8e-63 208.4 62.3 2.6e-15 56.4 0.7 5.1 5 0 0 5 5 5 5 LIM domain ATPase-cat_bd PF12156.8 PRP76435.1 - 0.0067 17.1 2.5 0.0067 17.1 2.5 5.2 5 2 2 7 7 7 1 Putative metal-binding domain of cation transport ATPase DUF362 PF04015.12 PRP76435.1 - 0.038 14.2 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) DUF3268 PF11672.8 PRP76436.1 - 6.1 7.2 8.6 0.94 9.8 0.2 2.7 3 0 0 3 3 3 0 zinc-finger-containing domain Mito_carr PF00153.27 PRP76437.1 - 1e-46 156.8 11.0 7.6e-20 70.6 0.8 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DAGK_cat PF00781.24 PRP76438.1 - 6.4e-26 90.4 0.2 1e-25 89.8 0.2 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.8 PRP76438.1 - 0.18 10.6 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LRR_12 PF18837.1 PRP76439.1 - 0.096 12.4 0.1 0.41 10.3 0.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeat DAGK_cat PF00781.24 PRP76440.1 - 1.4e-14 53.8 0.1 3e-12 46.3 0.1 2.4 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Get5_C PF18514.1 PRP76440.1 - 0.029 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Get5 C-terminal domain PNP_UDP_1 PF01048.20 PRP76441.1 - 2.7e-21 75.9 0.0 4.6e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Prenyltransf PF01255.19 PRP76442.1 - 2e-69 233.5 0.0 2.5e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CMD PF02627.20 PRP76443.1 - 0.00019 21.4 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF2393 PF09624.10 PRP76443.1 - 0.034 14.2 0.1 0.058 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) SinI PF08671.10 PRP76443.1 - 0.34 10.7 1.2 0.56 10.0 0.2 1.9 2 0 0 2 2 2 0 Anti-repressor SinI EF-hand_7 PF13499.6 PRP76444.1 - 2.9e-12 46.8 0.2 5.3e-07 30.0 0.1 3.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PRP76444.1 - 1.4e-11 43.4 2.2 6.2e-05 22.6 0.0 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 PRP76444.1 - 3.1e-10 38.8 1.4 5.7e-05 22.4 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PRP76444.1 - 4.6e-07 29.6 2.0 0.00027 20.7 0.1 4.2 3 2 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP76444.1 - 5.9e-05 22.4 1.0 0.0007 19.0 0.1 2.7 2 0 0 2 2 2 1 EF hand DAO PF01266.24 PRP76445.1 - 2.4e-45 155.6 6.7 4.5e-45 154.8 6.7 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 PRP76445.1 - 4.1e-05 23.1 0.1 0.007 15.8 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase Thi4 PF01946.17 PRP76445.1 - 0.0022 17.2 1.3 0.09 12.0 0.5 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 PRP76445.1 - 0.0055 16.9 0.5 0.015 15.5 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 PRP76445.1 - 0.0058 15.8 1.4 0.32 10.0 0.0 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 PRP76445.1 - 0.006 15.9 1.5 0.39 9.9 0.7 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PRP76445.1 - 0.015 14.1 3.3 0.056 12.3 1.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 PRP76445.1 - 0.029 13.5 6.0 0.4 9.7 6.0 2.1 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 PRP76445.1 - 0.087 13.4 0.8 0.16 12.6 0.3 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LuxS PF02664.15 PRP76445.1 - 0.15 11.8 0.3 3.7 7.2 0.1 2.2 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) EIF_2_alpha PF07541.12 PRP76446.1 - 3.9e-34 117.2 0.1 1.5e-33 115.4 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 PRP76446.1 - 1.9e-13 50.5 0.6 3.5e-13 49.7 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain T4_baseplate PF12322.8 PRP76446.1 - 0.035 13.6 1.5 0.088 12.3 0.3 2.2 2 1 0 2 2 2 0 T4 bacteriophage base plate protein MDM1 PF15501.6 PRP76447.1 - 0.0014 17.9 18.9 0.0015 17.8 18.9 1.1 1 0 0 1 1 1 1 Nuclear protein MDM1 SDA1 PF05285.12 PRP76447.1 - 0.0049 16.4 21.8 0.0059 16.1 21.8 1.1 1 0 0 1 1 1 1 SDA1 SLC12 PF03522.15 PRP76447.1 - 0.34 9.9 10.8 0.39 9.7 10.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 PRP76447.1 - 0.39 9.4 9.4 0.44 9.3 9.4 1.1 1 0 0 1 1 1 0 Raftlin Endostatin PF06482.11 PRP76447.1 - 0.62 9.5 5.7 0.63 9.4 5.7 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Afi1 PF07792.12 PRP76447.1 - 0.62 10.5 13.3 28 5.2 13.3 2.7 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking VIR_N PF15912.5 PRP76447.1 - 0.68 9.5 14.3 0.79 9.3 14.3 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal V_ATPase_I PF01496.19 PRP76447.1 - 1.1 7.1 7.0 1.3 6.9 7.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RR_TM4-6 PF06459.12 PRP76447.1 - 1.2 8.9 20.2 2.2 8.0 20.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 PRP76447.1 - 1.4 7.6 18.0 1.7 7.3 18.0 1.1 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 PRP76447.1 - 1.9 7.5 14.4 2.3 7.2 14.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC45 PF02724.14 PRP76447.1 - 2.7 6.2 21.0 3.3 5.9 21.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 PRP76447.1 - 5.6 5.8 10.5 9 5.2 10.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5427 PF10310.9 PRP76447.1 - 6.3 5.6 19.7 8.7 5.2 19.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) GREB1 PF15782.5 PRP76447.1 - 6.8 3.7 9.1 7.7 3.5 9.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FancD2 PF14631.6 PRP76447.1 - 8.6 3.6 11.2 10 3.3 11.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Peroxin-3 PF04882.12 PRP76447.1 - 8.7 5.2 15.4 12 4.8 15.4 1.1 1 0 0 1 1 1 0 Peroxin-3 zf-CCHH PF10283.9 PRP76448.1 - 4e-10 39.5 3.0 8.3e-10 38.5 2.1 2.0 1 1 1 2 2 2 1 PBZ domain BRCT PF00533.26 PRP76448.1 - 5.4e-07 29.9 0.0 1.4e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP76448.1 - 1.3e-06 28.8 0.0 3.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PRP76448.1 - 0.00074 19.4 0.1 0.0019 18.1 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain FHA_2 PF17913.1 PRP76448.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 FHA domain Pro-kuma_activ PF09286.11 PRP76449.1 - 2.3e-19 70.1 0.0 6.5e-18 65.4 0.0 2.2 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP76449.1 - 7e-06 25.5 0.9 1.4e-05 24.5 0.9 1.5 1 0 0 1 1 1 1 Subtilase family Pkinase_Tyr PF07714.17 PRP76451.1 - 4e-40 137.7 0.2 5.8e-40 137.2 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76451.1 - 3.9e-30 105.1 0.1 5.8e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP76451.1 - 8.7e-28 95.9 63.5 2.5e-09 36.7 4.0 8.4 5 2 4 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 PRP76451.1 - 1.9e-25 88.5 70.6 6.1e-06 26.5 0.6 10.7 8 3 2 10 10 10 10 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP76451.1 - 4.7e-09 36.6 3.8 1.6e-08 34.9 3.8 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP76451.1 - 0.00077 19.7 55.8 3.2 8.6 0.1 14.8 14 2 0 14 14 14 3 Leucine Rich Repeat Herpes_gE PF02480.16 PRP76451.1 - 0.083 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 PRP76451.1 - 0.088 13.7 1.5 0.21 12.5 0.2 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PRP76451.1 - 1.6 8.8 7.2 0.15 12.2 0.9 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Peptidase_S74 PF13884.6 PRP76452.1 - 6e-15 55.3 0.1 1.4e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase Pkinase_Tyr PF07714.17 PRP76453.1 - 2.7e-47 161.2 0.0 1.2e-31 109.9 0.1 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP76453.1 - 2e-43 148.7 0.0 7.9e-43 146.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP76453.1 - 0.00014 21.3 0.0 0.00028 20.3 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SWIRM PF04433.17 PRP76453.1 - 0.044 14.1 0.2 9 6.7 0.0 2.7 2 0 0 2 2 2 0 SWIRM domain PHO4 PF01384.20 PRP76454.1 - 1.6e-52 178.6 7.4 2.5e-52 178.0 7.4 1.3 1 0 0 1 1 1 1 Phosphate transporter family Ala_racemase_N PF01168.20 PRP76456.1 - 2.4e-25 89.5 0.0 2.9e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Mito_carr PF00153.27 PRP76457.1 - 8.8e-62 205.1 0.9 1.7e-21 76.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EGF_CA PF07645.15 PRP76457.1 - 1.4e-11 44.4 21.4 4.8e-07 29.9 6.0 7.9 5 1 2 7 7 7 2 Calcium-binding EGF domain EGF_2 PF07974.13 PRP76457.1 - 8.6e-07 29.2 48.7 0.00016 22.0 13.6 10.0 9 2 0 9 9 9 4 EGF-like domain Vps26 PF03643.15 PRP76458.1 - 1.6e-106 355.4 3.1 1.8e-106 355.2 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 DUF3244 PF11589.8 PRP76458.1 - 0.039 14.0 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) SH2 PF00017.24 PRP76459.1 - 1.2e-26 92.6 0.0 7e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP76459.1 - 1.1e-11 45.2 0.0 3.1e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 PF02762.14 PRP76459.1 - 1.2e-05 25.0 0.0 0.021 14.7 0.0 2.7 3 0 0 3 3 3 2 CBL proto-oncogene N-terminus, SH2-like domain IBP39 PF11422.8 PRP76459.1 - 0.0026 17.6 1.3 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 Initiator binding protein 39 kDa SH2_2 PF14633.6 PRP76459.1 - 0.03 13.7 7.6 0.16 11.4 0.0 3.3 3 1 0 3 3 3 0 SH2 domain Cas_VVA1548 PF09652.10 PRP76459.1 - 0.11 12.7 0.0 94 3.3 0.0 4.9 4 1 2 6 6 6 0 Putative CRISPR-associated protein (Cas_VVA1548) Ras PF00071.22 PRP76461.1 - 2.7e-64 215.6 1.3 3.2e-64 215.4 1.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP76461.1 - 2.1e-35 121.5 0.2 3.7e-35 120.7 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP76461.1 - 5.3e-18 65.1 0.4 6.1e-18 64.9 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP76461.1 - 4.6e-05 22.9 0.2 6e-05 22.5 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP76461.1 - 7.7e-05 22.3 0.4 0.00018 21.1 0.3 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP76461.1 - 9.2e-05 22.5 0.1 0.00021 21.4 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP76461.1 - 9.6e-05 22.4 1.3 0.12 12.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 PRP76461.1 - 0.002 17.6 0.2 0.0032 16.9 0.2 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PRP76461.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 PRP76461.1 - 0.027 14.9 0.1 0.37 11.2 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP76461.1 - 0.044 14.1 0.0 0.073 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PRP76461.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 PRP76461.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 PRP76461.1 - 0.073 13.1 0.1 0.11 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 PRP76461.1 - 0.12 12.9 0.1 0.22 12.1 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Mltc_N PF11873.8 PRP76461.1 - 0.14 11.8 1.1 9.7 5.9 0.1 2.2 2 0 0 2 2 2 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain C12orf66_like PF09404.10 PRP76462.1 - 9.3e-28 97.2 3.8 1.8e-27 96.3 3.8 1.4 1 1 0 1 1 1 1 KICSTOR complex C12orf66 like Ank_2 PF12796.7 PRP76463.1 - 1.5e-28 99.2 0.0 1.3e-07 32.1 0.0 3.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76463.1 - 3.1e-18 65.9 1.5 0.0024 18.4 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP76463.1 - 4e-14 52.5 1.7 0.043 14.2 0.1 6.8 3 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP76463.1 - 3.6e-08 33.5 0.1 3.2 8.4 0.0 6.7 6 2 1 7 7 7 1 Ankyrin repeat Ank_3 PF13606.6 PRP76463.1 - 8.5e-08 31.9 0.7 2 9.3 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeat DHquinase_I PF01487.15 PRP76463.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Type I 3-dehydroquinase Pkinase PF00069.25 PRP76465.1 - 0.0024 17.3 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76465.1 - 0.021 14.1 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase zf-C3HC4_3 PF13920.6 PRP76466.1 - 6.7e-07 29.1 12.8 1.2e-06 28.2 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP76466.1 - 3.4e-06 26.8 11.5 6.2e-06 26.0 11.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PRP76466.1 - 9.7e-06 25.5 8.8 4.2e-05 23.5 9.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PRP76466.1 - 1.5e-05 25.2 14.3 3.1e-05 24.2 14.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PRP76466.1 - 1.9e-05 24.5 13.8 4.1e-05 23.5 13.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PRP76466.1 - 0.0003 20.6 14.0 0.0003 20.6 14.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP76466.1 - 0.016 15.0 14.5 0.038 13.8 14.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps54_N PF10475.9 PRP76466.1 - 0.024 13.9 6.4 0.066 12.5 6.4 1.8 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex zf-RING_6 PF14835.6 PRP76466.1 - 0.15 11.9 6.8 0.28 11.1 5.3 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 PRP76466.1 - 0.19 11.5 6.2 0.69 9.7 6.2 2.1 1 0 0 1 1 1 0 RING-like zinc finger Fib_alpha PF08702.10 PRP76466.1 - 0.28 11.4 12.8 0.81 9.9 9.8 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family zf-rbx1 PF12678.7 PRP76466.1 - 0.56 10.5 8.2 1.6 9.1 8.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Lectin_N PF03954.14 PRP76466.1 - 0.67 9.7 5.7 1.8 8.3 5.4 2.0 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain KxDL PF10241.9 PRP76466.1 - 0.87 9.9 8.4 2 8.8 5.5 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein zf-C3HC4_4 PF15227.6 PRP76466.1 - 1.3 9.2 12.8 4.7 7.5 12.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PfkB PF00294.24 PRP76468.1 - 2.1e-58 198.0 0.7 2.6e-58 197.7 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 PRP76468.1 - 0.031 13.8 0.1 0.067 12.7 0.1 1.6 1 1 0 1 1 1 0 Carbohydrate kinase GMC_oxred_N PF00732.19 PRP76468.1 - 0.074 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 GMC oxidoreductase rve PF00665.26 PRP76470.1 - 3.3e-09 36.9 0.0 5.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain NEXCaM_BD PF16644.5 PRP76470.1 - 0.025 14.8 0.1 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin MBOAT_2 PF13813.6 PRP76470.1 - 0.035 14.4 0.2 0.08 13.2 0.2 1.5 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Med9 PF07544.13 PRP76470.1 - 0.044 13.9 0.1 9.6 6.4 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Chromo PF00385.24 PRP76471.1 - 2.2e-13 49.9 0.0 3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP76471.1 - 0.028 14.6 0.2 0.053 13.7 0.2 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DLH PF01738.18 PRP76474.1 - 3.3e-20 72.6 0.7 4e-20 72.3 0.7 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Glyco_hydro_16 PF00722.21 PRP76475.1 - 6.7e-20 71.3 0.4 1.1e-19 70.6 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 X8 PF07983.13 PRP76475.1 - 1.7e-12 47.8 1.9 4.3e-12 46.6 1.9 1.7 1 0 0 1 1 1 1 X8 domain Peroxidase_2 PF01328.17 PRP76476.1 - 4.2e-54 183.9 0.0 5.6e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 UCR_TM PF02921.14 PRP76476.1 - 0.096 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region FANCI_S4 PF14678.6 PRP76476.1 - 0.23 10.6 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 4 AdoMet_Synthase PF01941.19 PRP76477.1 - 0.16 10.7 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) LRR_6 PF13516.6 PRP76480.1 - 2.4e-44 145.6 34.1 1.2e-05 25.0 0.2 9.1 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 PRP76480.1 - 1.3e-10 41.3 9.7 0.021 15.2 0.1 5.4 1 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP76480.1 - 3.2e-09 36.1 0.0 39 5.4 0.0 7.4 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 PRP76480.1 - 9.6e-08 31.7 12.2 0.017 14.9 1.4 6.2 1 1 4 5 5 5 5 Leucine rich repeat DUF3701 PF12482.8 PRP76480.1 - 0.0014 18.7 6.2 56 3.9 0.0 6.3 2 2 5 7 7 7 0 Phage integrase protein Terminase_6C PF17289.2 PRP76480.1 - 0.014 15.5 0.0 12 6.0 0.0 3.4 1 1 2 4 4 4 0 Terminase RNaseH-like domain DUF1647 PF07801.11 PRP76480.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) NAD_binding_6 PF08030.12 PRP76480.1 - 0.64 10.1 12.4 90 3.2 2.2 5.7 2 2 0 2 2 2 0 Ferric reductase NAD binding domain AAA PF00004.29 PRP76482.1 - 1.7e-12 47.9 0.0 3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP76482.1 - 3.2e-05 24.4 0.2 0.014 15.8 0.0 2.3 1 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PRP76482.1 - 9e-05 22.8 0.0 0.00025 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PRP76482.1 - 0.0085 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PRP76482.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 PRP76482.1 - 0.062 12.7 0.1 9.6 5.6 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 PRP76482.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 PRP76482.1 - 0.15 12.0 0.2 4.2 7.2 0.1 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TetR_C_23 PF17931.1 PRP76483.1 - 0.053 13.6 0.2 0.069 13.3 0.2 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FAM176 PF14851.6 PRP76483.1 - 0.14 11.8 0.3 0.18 11.4 0.3 1.2 1 0 0 1 1 1 0 FAM176 family LURAP PF14854.6 PRP76484.1 - 0.21 11.6 0.4 0.3 11.0 0.4 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein PIF1 PF05970.14 PRP76486.1 - 1e-47 163.1 0.0 4e-35 121.6 0.0 2.4 1 1 1 2 2 2 2 PIF1-like helicase zf-PARP PF00645.18 PRP76486.1 - 1.4e-17 64.3 1.2 1.4e-17 64.3 1.2 3.0 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AAA_30 PF13604.6 PRP76486.1 - 1.3e-10 41.3 0.0 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP76486.1 - 0.00046 20.5 0.0 0.0012 19.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain SH3_13 PF18335.1 PRP76486.1 - 0.055 13.3 0.0 0.22 11.4 0.0 2.1 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ABC2_membrane PF01061.24 PRP76487.1 - 3.6e-82 274.8 57.5 3.3e-47 160.6 21.5 2.8 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 PRP76487.1 - 1.1e-35 123.1 0.5 8.8e-18 65.1 0.0 3.7 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 PRP76487.1 - 8.4e-24 83.3 11.5 1e-18 67.0 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter Peptidase_M16_C PF05193.21 PRP76487.1 - 6e-13 49.2 0.1 9.1e-11 42.1 0.0 3.5 3 0 0 3 3 3 1 Peptidase M16 inactive domain ABC2_membrane_3 PF12698.7 PRP76487.1 - 2.6e-08 33.4 47.3 7.9e-08 31.8 16.2 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 PRP76487.1 - 6.1e-07 30.0 0.0 1.8e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal Peptidase_M16 PF00675.20 PRP76487.1 - 1.9e-06 28.0 0.0 9.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Zeta_toxin PF06414.12 PRP76487.1 - 2.3e-06 27.0 0.3 0.056 12.7 0.0 3.4 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 PRP76487.1 - 1.6e-05 24.9 0.9 0.00071 19.5 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 PRP76487.1 - 0.00014 21.5 0.1 0.01 15.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 PRP76487.1 - 0.0009 19.4 1.0 2.1 8.5 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 PRP76487.1 - 0.0017 18.7 0.1 0.98 9.8 0.0 3.2 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 PRP76487.1 - 0.0036 16.9 0.5 0.011 15.3 0.3 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP76487.1 - 0.0084 16.4 0.0 0.49 10.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP76487.1 - 0.016 15.0 0.1 1.5 8.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 PRP76487.1 - 0.02 14.7 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 PRP76487.1 - 0.038 14.4 0.5 35 4.8 0.1 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PRP76487.1 - 0.076 12.9 0.3 0.99 9.3 0.4 2.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 PRP76487.1 - 0.091 12.3 0.0 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 PRP76487.1 - 0.14 12.7 0.0 7.8 7.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain M16C_assoc PF08367.11 PRP76487.1 - 2 7.5 5.7 6.7 5.8 5.8 1.9 1 1 0 1 1 1 0 Peptidase M16C associated AAA_23 PF13476.6 PRP76487.1 - 6.4 7.2 12.4 1.6 9.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain ThiF PF00899.21 PRP76488.1 - 1.3e-52 178.6 0.0 2.1e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family DEAD PF00270.29 PRP76488.1 - 4.3e-44 150.4 0.3 1.6e-43 148.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP76488.1 - 5.5e-26 91.1 0.1 1.5e-25 89.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 PRP76488.1 - 1.1e-11 44.8 8.2 2e-11 44.0 6.3 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain 2-Hacid_dh_C PF02826.19 PRP76488.1 - 0.021 14.2 0.0 0.057 12.8 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 PRP76488.1 - 0.038 14.4 0.0 0.25 11.8 0.0 2.5 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 PRP76488.1 - 0.068 12.7 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TIR_3 PF18567.1 PRP76488.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain Sacchrp_dh_NADP PF03435.18 PRP76488.1 - 1.5 9.1 4.6 11 6.3 1.3 3.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF724 PF05266.14 PRP76489.1 - 0.01 15.6 4.6 0.01 15.6 4.6 6.3 2 2 3 6 6 6 0 Protein of unknown function (DUF724) Sugarporin_N PF11471.8 PRP76489.1 - 4.8 7.2 16.5 0.085 12.8 3.4 3.5 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension PC4 PF02229.16 PRP76490.1 - 3.4e-15 55.4 0.4 7.7e-15 54.3 0.4 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DEK_C PF08766.11 PRP76490.1 - 4.8e-05 23.2 1.7 8.3e-05 22.4 0.9 2.0 1 1 0 1 1 1 1 DEK C terminal domain DUF4795 PF16043.5 PRP76490.1 - 0.012 15.2 4.6 0.012 15.2 4.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) LRR_RI_capping PF18779.1 PRP76490.1 - 0.014 15.0 1.0 0.014 15.0 1.0 2.0 2 0 0 2 2 2 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Nitr_red_bet_C PF14711.6 PRP76490.1 - 0.022 14.5 0.1 0.08 12.7 0.0 2.1 2 1 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal DUF2797 PF10977.8 PRP76490.1 - 0.035 14.0 0.4 0.049 13.5 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2797) DUF5394 PF17372.2 PRP76490.1 - 0.043 13.4 3.1 0.049 13.2 2.6 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5394) FlaC_arch PF05377.11 PRP76490.1 - 1.3 9.4 6.0 13 6.3 1.5 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Peptidase_C78 PF07910.13 PRP76491.1 - 1.2e-47 162.2 0.0 1.5e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C70 PF12385.8 PRP76491.1 - 0.11 12.5 0.0 5.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 ABC2_membrane PF01061.24 PRP76492.1 - 1.1e-31 109.9 20.4 1.1e-31 109.9 20.4 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PRP76492.1 - 1.3e-23 84.0 0.0 2.3e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PRP76492.1 - 0.00088 19.2 0.6 0.69 9.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PRP76492.1 - 0.003 17.0 0.3 0.043 13.3 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 PRP76492.1 - 0.0041 16.3 18.6 0.0041 16.3 18.6 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein EGF_2 PF07974.13 PRP76492.1 - 0.02 15.2 0.3 0.02 15.2 0.3 2.5 2 0 0 2 2 2 0 EGF-like domain RsgA_GTPase PF03193.16 PRP76492.1 - 0.022 14.7 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 PRP76492.1 - 0.15 12.3 0.0 0.69 10.2 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 PRP76492.1 - 0.18 11.6 0.3 0.41 10.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 PRP76492.1 - 0.18 12.4 0.1 0.4 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain LAMTOR5 PF16672.5 PRP76495.1 - 2e-15 56.5 0.2 3.1e-15 55.9 0.2 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 PRP76495.1 - 0.18 11.6 0.2 0.3 10.9 0.2 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain Acyltransferase PF01553.21 PRP76496.1 - 2.4e-20 72.6 0.0 4.3e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 PRP76496.1 - 5.3e-17 61.7 3.9 7.9e-17 61.1 0.9 2.6 2 1 1 3 3 3 1 Acyltransferase C-terminus 7tm_1 PF00001.21 PRP76498.1 - 5 6.4 12.5 33 3.7 1.2 2.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) RasGEF PF00617.19 PRP76499.1 - 1.4e-53 181.7 0.1 2.5e-53 180.9 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP76499.1 - 2.1e-05 24.7 0.4 7.7e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 PRP76500.1 - 1.4e-50 171.0 0.1 1.7e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP76500.1 - 7.7e-19 68.1 0.0 1.2e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP76500.1 - 1.7e-08 34.1 0.1 2e-08 33.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP76500.1 - 4.9e-06 26.2 0.3 1.2e-05 24.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP76500.1 - 0.0011 19.0 0.5 0.48 10.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase DUF561 PF04481.12 PRP76500.1 - 0.0017 17.6 0.0 0.0024 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF561) MMR_HSR1 PF01926.23 PRP76500.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4815 PF16075.5 PRP76500.1 - 0.11 10.8 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4815) TFX_C PF14601.6 PRP76500.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Pkinase_Tyr PF07714.17 PRP76501.1 - 5.7e-25 88.1 4.7 1.6e-16 60.4 0.4 4.3 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 PRP76501.1 - 5.9e-24 84.9 0.8 2.3e-18 66.5 0.4 2.7 2 1 0 2 2 2 2 Protein kinase domain GPS PF01825.21 PRP76501.1 - 1.3e-19 70.4 20.2 2.5e-10 40.7 1.9 4.4 4 0 0 4 4 4 2 GPCR proteolysis site, GPS, motif WYL_2 PF10902.8 PRP76501.1 - 0.11 12.9 0.6 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 WYL_2, Sm-like SH3 beta-barrel fold PMR5N PF14416.6 PRP76501.1 - 0.6 10.5 3.2 2.4 8.5 0.6 2.6 2 0 0 2 2 2 0 PMR5 N terminal Domain DUF3951 PF13131.6 PRP76504.1 - 0.066 13.4 0.3 0.066 13.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF2207 PF09972.9 PRP76504.1 - 0.16 10.7 1.6 0.2 10.4 1.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FixQ PF05545.11 PRP76504.1 - 0.19 11.7 0.3 0.19 11.7 0.3 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ NCD3G PF07562.14 PRP76505.1 - 0.019 14.9 0.7 0.019 14.9 0.7 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Chlam_PMP PF02415.17 PRP76505.1 - 8.3 7.1 7.9 2.2 8.9 0.1 3.6 3 1 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ephrin_rec_like PF07699.13 PRP76505.1 - 9.4 6.1 11.9 0.88 9.4 0.8 3.1 3 0 0 3 3 3 0 Putative ephrin-receptor like Aldedh PF00171.22 PRP76506.1 - 5.7e-127 424.0 0.0 7.1e-127 423.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AhpC-TSA PF00578.21 PRP76507.1 - 2.5e-19 69.4 0.1 4.1e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PRP76507.1 - 1.3e-15 57.4 0.0 1.9e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 PRP76507.1 - 3.8e-15 56.0 0.1 7.3e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PRP76507.1 - 1.3e-11 44.3 0.3 1.4e-09 37.9 0.1 2.5 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 PRP76507.1 - 1.2e-05 25.7 0.1 2.8e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 PRP76507.1 - 0.00044 20.4 0.1 1.4 9.2 0.0 3.0 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin_9 PF14595.6 PRP76507.1 - 0.0022 17.8 0.1 0.63 9.8 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin HeH PF12949.7 PRP76507.1 - 0.0026 17.4 0.2 0.0044 16.7 0.2 1.3 1 0 0 1 1 1 1 HeH/LEM domain DUF899 PF05988.12 PRP76507.1 - 0.0081 15.7 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 PRP76507.1 - 0.025 14.7 0.0 0.098 12.8 0.0 1.8 1 1 0 2 2 2 0 AhpC/TSA antioxidant enzyme TraF PF13728.6 PRP76507.1 - 0.098 12.5 1.2 2.4 7.9 0.2 2.3 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 PRP76507.1 - 0.25 11.6 1.3 0.98 9.6 1.3 2.0 1 1 0 1 1 1 0 Thioredoxin-like Beta_helix PF13229.6 PRP76508.1 - 3.2e-06 27.1 24.9 0.0014 18.5 3.8 4.4 4 1 0 4 4 4 2 Right handed beta helix region NCD3G PF07562.14 PRP76508.1 - 6.7e-05 22.8 14.8 0.011 15.7 0.7 3.5 3 0 0 3 3 3 2 Nine Cysteines Domain of family 3 GPCR Chlam_PMP PF02415.17 PRP76508.1 - 0.0064 16.9 6.1 3.3 8.4 0.2 4.2 3 0 0 3 3 3 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Amdase PF17645.1 PRP76508.1 - 0.13 11.9 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Arylmalonate decarboxylase Ephrin_rec_like PF07699.13 PRP76508.1 - 0.84 9.5 21.4 2 8.2 3.0 4.1 3 0 0 3 3 3 0 Putative ephrin-receptor like Beta_helix PF13229.6 PRP76509.1 - 0.0047 16.8 3.5 0.0047 16.8 3.5 3.2 2 1 0 3 3 3 1 Right handed beta helix region NCD3G PF07562.14 PRP76509.1 - 0.013 15.5 0.5 0.013 15.5 0.5 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 PRP76509.1 - 0.38 10.6 8.0 0.63 9.9 0.7 3.0 2 0 0 2 2 2 0 Putative ephrin-receptor like Chlam_PMP PF02415.17 PRP76509.1 - 7.9 7.2 6.6 0.84 10.2 0.2 2.8 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NCD3G PF07562.14 PRP76510.1 - 0.041 13.9 0.4 0.041 13.9 0.4 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 PRP76510.1 - 2.2 8.1 7.1 0.9 9.4 0.7 2.9 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-C3HC4 PF00097.25 PRP76512.1 - 2e-07 30.8 13.0 2e-07 30.8 13.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP76512.1 - 6.8e-07 29.3 15.0 6.8e-07 29.3 15.0 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PRP76512.1 - 2e-06 27.7 10.3 2e-06 27.7 10.3 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP76512.1 - 2.1e-06 27.5 12.4 2.1e-06 27.5 12.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP76512.1 - 2.4e-06 27.3 10.6 2.4e-06 27.3 10.6 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP76512.1 - 1e-05 25.7 12.0 1e-05 25.7 12.0 2.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PRP76512.1 - 0.00028 20.8 11.8 0.00028 20.8 11.8 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.24 PRP76512.1 - 0.0051 16.9 14.3 0.0051 16.9 14.3 3.5 2 2 0 2 2 2 1 B-box zinc finger Na_H_antiport_2 PF13726.6 PRP76512.1 - 0.16 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Na+-H+ antiporter family MTP18 PF10558.9 PRP76513.1 - 1.6e-57 194.2 10.1 1.4e-28 99.9 2.7 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) Cation_efflux PF01545.21 PRP76515.1 - 3e-33 115.2 10.7 4e-33 114.8 10.7 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 PRP76515.1 - 0.02 14.1 1.6 0.05 12.8 1.6 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter Phage_holin_2_4 PF16082.5 PRP76515.1 - 0.17 11.6 0.4 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like TPR_12 PF13424.6 PRP76517.1 - 1.9e-186 604.8 75.3 2.2e-20 72.7 2.5 20.7 11 5 8 21 21 21 19 Tetratricopeptide repeat TPR_10 PF13374.6 PRP76517.1 - 3.4e-171 551.3 58.8 1.9e-10 40.3 0.0 26.0 26 0 0 26 26 25 22 Tetratricopeptide repeat TPR_7 PF13176.6 PRP76517.1 - 8.1e-65 210.2 66.7 1.5e-05 24.7 0.0 24.9 25 0 0 25 25 25 13 Tetratricopeptide repeat TPR_1 PF00515.28 PRP76517.1 - 2.4e-60 198.0 88.6 4.5e-06 26.3 0.1 25.4 26 0 0 26 26 26 14 Tetratricopeptide repeat TPR_2 PF07719.17 PRP76517.1 - 2e-58 189.9 102.7 5.8e-05 22.9 0.2 27.2 28 0 0 28 28 28 15 Tetratricopeptide repeat TPR_8 PF13181.6 PRP76517.1 - 2.5e-47 155.2 101.1 3.3e-05 23.8 0.4 25.5 26 0 0 26 26 24 14 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP76517.1 - 1.8e-39 136.1 30.9 1.7e-08 34.2 0.2 9.5 3 2 5 9 9 9 7 MalT-like TPR region TPR_19 PF14559.6 PRP76517.1 - 7.2e-34 116.1 31.8 4.3e-05 23.9 0.1 17.4 11 5 5 18 18 18 8 Tetratricopeptide repeat TPR_16 PF13432.6 PRP76517.1 - 1.8e-33 114.9 40.4 7.3e-07 29.7 0.1 17.7 15 6 2 17 17 16 5 Tetratricopeptide repeat TPR_4 PF07721.14 PRP76517.1 - 3e-26 89.3 6.8 0.46 11.3 0.0 17.3 20 0 0 20 20 17 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP76517.1 - 5.8e-25 85.9 50.2 0.037 14.8 0.0 21.1 20 4 4 24 24 19 2 Tetratricopeptide repeat CLU PF13236.6 PRP76517.1 - 7e-24 84.9 0.0 1.7e-23 83.6 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria TPR_17 PF13431.6 PRP76517.1 - 1.4e-22 78.4 29.4 0.2 12.1 0.0 19.0 22 0 0 22 22 18 5 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP76517.1 - 1.3e-11 44.5 43.4 0.015 15.5 1.1 13.1 8 2 5 14 14 12 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PRP76517.1 - 3.5e-06 27.3 55.2 0.14 12.8 0.1 16.9 21 0 0 21 21 15 2 Tetratricopeptide repeat DUF2225 PF09986.9 PRP76517.1 - 0.00023 21.0 35.8 0.3 10.8 1.2 8.2 4 2 5 9 9 7 3 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.6 PRP76517.1 - 0.00035 20.2 59.9 0.036 13.7 0.4 15.2 16 1 0 16 16 15 3 TPR repeat eIF3_p135 PF12807.7 PRP76517.1 - 0.0012 18.9 3.2 0.0014 18.7 0.4 2.5 1 1 1 2 2 2 1 Translation initiation factor eIF3 subunit 135 PPR PF01535.20 PRP76517.1 - 0.0014 18.7 29.9 12 6.4 0.0 13.2 17 0 0 17 17 14 0 PPR repeat SHNi-TPR PF10516.9 PRP76517.1 - 0.0025 17.2 9.4 4.9 6.7 0.0 7.9 9 0 0 9 9 7 2 SHNi-TPR RPN7 PF10602.9 PRP76517.1 - 0.0027 17.5 32.6 9.3 5.9 0.9 12.2 7 3 5 13 13 11 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 PRP76517.1 - 0.0042 17.1 34.7 0.37 10.8 0.0 12.6 13 0 0 13 13 13 1 Tetratricopeptide repeat MIT PF04212.18 PRP76517.1 - 0.0044 17.1 57.6 0.18 11.9 1.7 13.9 13 3 2 15 15 13 2 MIT (microtubule interacting and transport) domain HemY_N PF07219.13 PRP76517.1 - 0.0082 16.3 9.2 20 5.5 0.1 7.3 7 2 2 9 9 9 0 HemY protein N-terminus Arm_3 PF16186.5 PRP76517.1 - 0.0093 15.5 0.2 0.42 10.2 0.0 3.5 4 0 0 4 4 2 1 Atypical Arm repeat DUF4404 PF14357.6 PRP76517.1 - 0.019 15.6 13.3 11 6.7 0.1 9.0 8 3 3 11 11 9 0 Domain of unknown function (DUF4404) TPR_20 PF14561.6 PRP76517.1 - 0.093 13.1 10.8 7.5 7.0 0.1 7.8 8 2 1 9 9 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 PRP76517.1 - 0.22 11.7 8.5 18 5.5 0.1 6.0 6 1 0 6 6 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 PRP76517.1 - 0.27 10.9 23.9 1.1 8.9 0.1 7.7 8 1 0 8 8 6 0 Tetratricopeptide repeat-like domain DUF4810 PF16068.5 PRP76517.1 - 0.4 11.2 9.5 16 6.1 1.7 6.0 4 1 1 5 5 4 0 Domain of unknown function (DUF4810) RPN6_N PF18055.1 PRP76517.1 - 1.4 9.3 24.4 3.6 8.0 0.0 8.2 6 1 2 8 8 7 0 26S proteasome regulatory subunit RPN6 N-terminal domain XG_FTase PF03254.13 PRP76518.1 - 1.1e-13 50.7 2.8 3e-06 26.1 0.0 3.0 2 1 0 2 2 2 2 Xyloglucan fucosyltransferase Med30 PF11315.8 PRP76520.1 - 0.00036 20.7 11.2 0.016 15.4 5.6 3.0 2 0 0 2 2 2 2 Mediator complex subunit 30 DUF2321 PF10083.9 PRP76520.1 - 0.33 10.6 4.4 0.11 12.1 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) DsrC PF04358.13 PRP76520.1 - 4.3 7.9 7.8 43 4.7 0.3 4.9 4 1 0 5 5 5 0 DsrC like protein Galactosyl_T PF01762.21 PRP76521.1 - 1.2e-09 38.3 0.6 9.3e-07 28.9 0.0 2.8 1 1 1 2 2 2 2 Galactosyltransferase FAA_hydrolase PF01557.18 PRP76522.1 - 6.7e-60 202.5 0.0 7.7e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Gly_transf_sug PF04488.15 PRP76523.1 - 3.3e-11 43.6 0.1 9.2e-11 42.2 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SOGA PF11365.8 PRP76523.1 - 0.052 14.7 0.0 0.13 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein SOGA Pkinase PF00069.25 PRP76524.1 - 2.2e-49 168.2 0.0 2.5e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76524.1 - 1.3e-25 90.1 0.0 1.8e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP76524.1 - 2e-05 24.0 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP76524.1 - 0.00021 20.4 2.0 0.00059 18.9 2.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP76524.1 - 0.0007 19.6 0.1 0.0017 18.3 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP76524.1 - 0.00083 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 PRP76524.1 - 0.058 13.0 0.8 0.11 12.0 0.2 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase TOH_N PF12549.8 PRP76525.1 - 7.2 6.6 8.5 14 5.7 0.0 3.7 3 1 1 4 4 4 0 Tyrosine hydroxylase N terminal WD40 PF00400.32 PRP76526.1 - 2.6e-10 40.7 0.6 0.0034 18.2 0.0 3.7 4 1 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76526.1 - 0.00019 21.7 0.0 0.00079 19.7 0.0 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 PRP76526.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Coatomer_WDAD PF04053.14 PRP76526.1 - 0.017 14.2 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Ge1_WD40 PF16529.5 PRP76526.1 - 0.082 11.8 0.0 1.7 7.6 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 PRP76526.1 - 0.11 13.0 0.0 0.42 11.2 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 PRP76527.1 - 1.1e-12 48.2 0.2 6.7e-06 26.8 0.2 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76527.1 - 0.0021 18.4 0.1 0.084 13.2 0.1 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP76527.1 - 0.082 11.6 0.1 0.23 10.2 0.1 1.7 1 1 1 2 2 2 0 Nup133 N terminal like DUF5046 PF16465.5 PRP76527.1 - 0.11 11.9 0.1 0.23 10.9 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) STAG PF08514.11 PRP76528.1 - 7.5e-23 80.6 0.7 6.4e-22 77.6 0.7 2.8 1 0 0 1 1 1 1 STAG domain HEAT PF02985.22 PRP76528.1 - 8.6e-07 28.7 1.7 0.052 13.8 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 PRP76528.1 - 9.2e-06 26.0 0.0 0.043 14.2 0.0 4.1 2 1 0 3 3 3 2 HEAT repeats DUF3535 PF12054.8 PRP76528.1 - 0.00047 19.5 0.1 0.00047 19.5 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) Cnd1 PF12717.7 PRP76528.1 - 0.001 19.1 8.2 0.0028 17.7 0.2 4.7 4 3 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF2385 PF09539.10 PRP76528.1 - 0.94 10.0 4.1 1 9.9 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2385) TTRAP PF14203.6 PRP76528.1 - 2.8 8.0 7.0 14 5.8 0.1 4.8 4 0 0 4 4 4 0 Putative tranposon-transfer assisting protein XH PF03469.14 PRP76529.1 - 0.0074 16.2 0.5 0.0093 15.9 0.5 1.2 1 0 0 1 1 1 1 XH domain PBP_sp32 PF07222.12 PRP76529.1 - 0.045 13.2 2.0 0.055 12.9 2.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 VPS38 PF17649.1 PRP76529.1 - 0.39 9.6 2.4 0.45 9.3 2.4 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Peptidase_M16 PF00675.20 PRP76530.1 - 6.4e-35 120.3 0.0 1.3e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PRP76530.1 - 1.2e-25 90.6 0.0 3.5e-25 89.1 0.0 1.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain PTCB-BRCT PF12738.7 PRP76530.1 - 0.028 14.4 0.3 1.9 8.5 0.1 2.7 1 1 1 2 2 2 0 twin BRCT domain UQ_con PF00179.26 PRP76531.1 - 8.6e-18 64.3 0.1 1.8e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Tub PF01167.18 PRP76532.1 - 3.5e-76 256.1 0.0 4.4e-75 252.5 0.0 2.3 1 1 0 1 1 1 1 Tub family Methyltransf_32 PF13679.6 PRP76532.1 - 7.9e-22 77.9 2.5 3e-21 76.0 2.5 1.9 1 1 0 1 1 1 1 Methyltransferase domain DUF3527 PF12043.8 PRP76532.1 - 0.0045 16.6 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3527) TRM13 PF05206.14 PRP76532.1 - 0.049 13.2 1.1 3.2 7.2 0.2 2.9 3 0 0 3 3 3 0 Methyltransferase TRM13 His_Phos_2 PF00328.22 PRP76533.1 - 4.3e-63 214.0 0.1 6.3e-63 213.4 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 PRP76533.1 - 4.6e-33 113.2 0.1 9.8e-33 112.2 0.1 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 PRP76533.1 - 2.1e-06 27.5 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Swi3 PF07962.12 PRP76533.1 - 0.12 12.3 0.0 0.49 10.4 0.0 2.1 1 1 0 1 1 1 0 Replication Fork Protection Component Swi3 TFX_C PF14601.6 PRP76533.1 - 0.16 12.0 0.1 0.98 9.4 0.0 2.3 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term Peptidase_S24 PF00717.23 PRP76534.1 - 5.1e-14 52.0 0.0 8.6e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 PRP76534.1 - 5.5e-05 23.0 0.0 0.00023 21.0 0.0 1.9 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 KorB_C PF06613.11 PRP76534.1 - 0.12 12.4 0.1 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain Sec63 PF02889.16 PRP76535.1 - 7.5e-23 81.0 0.1 1.1e-22 80.5 0.1 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 PRP76535.1 - 8.7e-19 67.4 0.8 1.9e-18 66.4 0.8 1.6 1 0 0 1 1 1 1 DnaJ domain Chlor_dismutase PF06778.12 PRP76535.1 - 0.042 13.4 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Chlorite dismutase Tetraspanin PF00335.20 PRP76535.1 - 0.053 13.2 1.2 0.57 9.8 0.2 2.3 2 0 0 2 2 2 0 Tetraspanin family EphA2_TM PF14575.6 PRP76535.1 - 0.24 12.3 0.7 12 6.9 0.0 3.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RIG-I_C PF18119.1 PRP76536.1 - 0.012 15.6 0.4 0.012 15.6 0.4 2.0 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain X8 PF07983.13 PRP76537.1 - 3.4e-52 175.1 37.0 8.9e-12 45.5 1.5 5.4 5 0 0 5 5 5 5 X8 domain Glyco_hydro_17 PF00332.18 PRP76537.1 - 4e-07 29.9 2.2 1.2e-06 28.4 1.2 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 DUF226 PF02890.14 PRP76537.1 - 0.0011 18.9 0.2 0.62 10.1 0.0 2.6 2 0 0 2 2 2 2 Borrelia family of unknown function DUF226 AlaE PF06610.13 PRP76537.1 - 0.0082 16.2 0.0 4.1 7.4 0.0 2.8 3 0 0 3 3 3 2 L-alanine exporter DUF2989 PF11207.8 PRP76537.1 - 0.011 15.5 3.9 23 4.7 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2989) RNF220 PF15926.5 PRP76538.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 RasGEF PF00617.19 PRP76540.1 - 6e-37 127.6 0.1 2.4e-36 125.6 0.1 2.2 1 0 0 1 1 1 1 RasGEF domain LRR_8 PF13855.6 PRP76540.1 - 6.8e-33 112.2 61.4 7.1e-12 44.9 6.1 6.9 4 2 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PRP76540.1 - 2.8e-28 97.5 65.7 2.1e-06 27.9 0.8 9.5 2 2 7 11 11 11 11 Leucine Rich repeats (2 copies) Drf_GBD PF06371.13 PRP76540.1 - 1e-12 48.1 0.8 2.1e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PRP76540.1 - 3.6e-12 46.3 0.6 1.2e-11 44.6 0.6 1.8 1 0 0 1 1 1 1 Diaphanous FH3 Domain LRR_9 PF14580.6 PRP76540.1 - 3.1e-09 36.6 28.7 0.0054 16.2 0.3 5.0 3 1 1 5 5 5 4 Leucine-rich repeat RasGEF_N PF00618.20 PRP76540.1 - 3.8e-07 30.3 0.0 1.3e-06 28.6 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif FERM_f0 PF16511.5 PRP76540.1 - 0.00085 19.6 0.5 1.6 9.1 0.1 3.2 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM LRR_6 PF13516.6 PRP76540.1 - 0.0022 17.9 38.7 0.57 10.4 0.1 9.9 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 PRP76540.1 - 0.04 14.5 38.5 15 6.7 0.1 10.8 11 1 0 11 11 9 0 Leucine Rich Repeat DUF1411 PF07199.11 PRP76540.1 - 0.19 11.3 1.5 0.35 10.5 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1411) Ras PF00071.22 PRP76541.1 - 2.7e-48 163.7 0.3 3.1e-48 163.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP76541.1 - 2.5e-31 108.4 0.2 3.8e-31 107.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP76541.1 - 1.5e-13 50.5 0.1 2e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP76541.1 - 2.6e-05 23.7 0.0 4.3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP76541.1 - 0.00048 20.2 0.0 0.00075 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 PRP76541.1 - 0.007 16.1 0.2 0.13 12.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.10 PRP76541.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PRP76541.1 - 0.089 13.2 0.0 0.13 12.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 PRP76541.1 - 0.18 11.8 0.2 0.69 10.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 PRP76542.1 - 7.8e-17 61.5 0.0 2.1e-16 60.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP76542.1 - 5.4e-06 25.8 0.6 0.00082 18.7 0.1 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP76542.1 - 0.00011 22.4 0.1 0.00034 20.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PRP76542.1 - 0.0002 21.8 0.1 0.0045 17.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP76542.1 - 0.00035 20.3 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase 3HCDH_N PF02737.18 PRP76542.1 - 0.0044 16.9 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.10 PRP76542.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 PRP76542.1 - 0.035 13.4 0.1 0.95 8.7 0.1 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PRP76542.1 - 0.041 13.5 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 PRP76542.1 - 0.053 12.6 0.8 0.18 10.9 0.8 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 PRP76542.1 - 0.073 11.8 0.2 8.2 5.0 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Myosin_N PF02736.19 PRP76542.1 - 0.27 11.1 1.2 0.6 10.0 0.6 1.9 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain PPR_2 PF13041.6 PRP76543.1 - 2.5e-05 24.3 3.5 0.0023 18.1 0.0 3.8 3 2 2 5 5 5 1 PPR repeat family PPR_3 PF13812.6 PRP76543.1 - 4.7e-05 23.4 1.3 0.015 15.4 0.0 2.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP76543.1 - 0.075 12.4 0.3 0.21 10.9 0.2 1.7 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP GSDH PF07995.11 PRP76544.1 - 3.3e-33 115.4 0.0 8.3e-32 110.8 0.0 2.6 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 PRP76544.1 - 1e-15 57.3 20.3 1.4e-11 44.0 3.2 3.7 3 0 0 3 3 3 2 PKD domain TMEM154 PF15102.6 PRP76544.1 - 0.048 13.6 2.2 0.1 12.5 2.2 1.6 1 0 0 1 1 1 0 TMEM154 protein family WD40 PF00400.32 PRP76544.1 - 0.18 12.7 2.9 8.8 7.4 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Ank_2 PF12796.7 PRP76545.1 - 9.4e-17 61.4 0.1 1.9e-05 25.1 0.0 4.7 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP76545.1 - 2.3e-14 53.2 0.7 0.15 12.4 0.1 7.3 2 2 6 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP76545.1 - 1.4e-13 51.1 0.1 0.0077 16.8 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76545.1 - 3.5e-08 33.1 0.0 6.1 7.8 0.0 7.2 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 PRP76545.1 - 7.8e-07 29.3 5.8 0.83 10.2 0.2 7.2 7 2 0 7 7 7 2 Ankyrin repeat LRR_8 PF13855.6 PRP76546.1 - 1.2e-24 85.8 45.7 1.7e-07 30.9 1.6 6.7 5 1 0 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PRP76546.1 - 1.2e-18 66.9 59.9 2.1e-05 24.8 3.1 8.9 5 3 4 9 9 9 9 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP76546.1 - 1.9e-08 34.7 3.6 4.4e-08 33.5 3.6 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_9 PF14580.6 PRP76546.1 - 4.3e-05 23.1 6.1 0.1 12.1 0.2 3.4 1 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 PRP76546.1 - 5.8e-05 23.1 29.6 1.3 9.9 0.8 9.5 10 1 0 10 10 10 4 Leucine Rich Repeat Pkinase_Tyr PF07714.17 PRP76548.1 - 2.5e-28 99.1 0.3 3.5e-28 98.6 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76548.1 - 5.8e-18 65.2 0.1 8.8e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP76548.1 - 4.2e-09 36.8 3.9 1.1e-08 35.5 3.9 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Cas9_a PF18470.1 PRP76548.1 - 0.065 12.8 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain CD34_antigen PF06365.12 PRP76548.1 - 0.11 12.1 0.9 0.39 10.3 1.1 1.8 1 1 0 1 1 1 0 CD34/Podocalyxin family GRAM PF02893.20 PRP76551.1 - 9.5e-06 25.5 0.4 9.5e-06 25.5 0.4 2.1 2 0 0 2 2 2 1 GRAM domain YabA PF06156.13 PRP76551.1 - 0.0012 19.4 4.7 0.0012 19.4 4.7 5.2 3 1 2 6 6 6 1 Initiation control protein YabA Spectrin PF00435.21 PRP76551.1 - 0.013 16.0 3.0 0.013 16.0 3.0 4.2 1 1 3 4 4 4 0 Spectrin repeat ZapB PF06005.12 PRP76551.1 - 0.029 14.8 1.6 0.029 14.8 1.6 5.9 2 1 0 4 4 4 0 Cell division protein ZapB HAP1_N PF04849.13 PRP76551.1 - 0.5 9.5 61.2 0.021 14.0 6.6 3.2 1 1 2 3 3 3 0 HAP1 N-terminal conserved region CALCOCO1 PF07888.11 PRP76551.1 - 2.1 7.1 50.7 0.11 11.3 33.8 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4472 PF14739.6 PRP76551.1 - 9.5 7.0 49.9 2.7 8.8 21.5 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Pkinase_Tyr PF07714.17 PRP76552.1 - 2.4e-26 92.6 0.3 3.6e-26 92.0 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76552.1 - 1e-16 61.1 0.0 1.6e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP76552.1 - 2e-14 53.1 43.0 2e-05 24.3 1.4 7.0 5 2 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 PRP76552.1 - 1.7e-09 37.8 67.8 0.0017 18.7 8.2 9.0 5 3 5 11 11 11 5 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP76552.1 - 3.5e-09 37.0 3.5 9.9e-09 35.6 3.5 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_9 PF14580.6 PRP76552.1 - 7.9e-05 22.2 9.5 0.0049 16.4 3.7 2.9 2 1 1 3 3 3 2 Leucine-rich repeat IPI_T4 PF11634.8 PRP76552.1 - 0.015 15.3 0.1 0.046 13.7 0.1 1.8 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 CHCH PF06747.13 PRP76553.1 - 0.00056 20.0 4.8 0.00056 20.0 4.8 1.8 2 0 0 2 2 2 1 CHCH domain NDUF_B7 PF05676.13 PRP76553.1 - 0.00098 18.8 4.2 0.0013 18.4 4.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 PRP76553.1 - 0.014 15.4 6.7 0.02 14.9 6.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 PRP76553.1 - 0.09 12.8 6.2 0.1 12.6 3.9 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Autoind_bind PF03472.15 PRP76553.1 - 0.14 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Autoinducer binding domain RRP14 PF15459.6 PRP76553.1 - 0.16 12.6 3.6 0.34 11.5 3.6 1.6 1 1 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Kelch_3 PF13415.6 PRP76554.1 - 8.7e-53 175.8 16.9 2.1e-09 37.4 0.1 7.3 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP76554.1 - 8e-40 134.2 7.5 9.5e-08 31.9 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PRP76554.1 - 1.4e-36 124.2 13.5 9.1e-10 38.4 0.1 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP76554.1 - 1.4e-35 120.4 6.5 3e-08 33.7 0.1 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PRP76554.1 - 2.9e-35 119.6 8.2 2.4e-07 30.2 0.3 6.4 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 PRP76554.1 - 8.8e-25 87.1 0.7 1.6e-21 76.6 0.4 2.3 1 1 1 2 2 2 2 BTB/POZ domain Kelch_2 PF07646.15 PRP76554.1 - 1.2e-20 72.6 12.9 6.6e-05 22.7 0.1 7.3 7 1 0 7 7 7 5 Kelch motif RAG2 PF03089.14 PRP76554.1 - 0.015 14.3 1.0 6.1 5.7 0.0 4.0 3 2 1 4 4 4 0 Recombination activating protein 2 Seryl_tRNA_N PF02403.22 PRP76555.1 - 0.016 15.4 8.2 0.016 15.4 8.2 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cob_adeno_trans PF01923.18 PRP76555.1 - 0.098 12.8 8.4 3.1 7.9 0.0 3.0 2 1 1 3 3 3 0 Cobalamin adenosyltransferase DUF3349 PF11829.8 PRP76555.1 - 0.33 11.7 5.1 0.24 12.2 0.4 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF3349) YlbD_coat PF14071.6 PRP76555.1 - 0.6 10.4 8.8 0.68 10.2 2.3 2.9 2 1 1 3 3 3 0 Putative coat protein BLOC1_2 PF10046.9 PRP76555.1 - 1.1 9.7 19.3 4.3 7.7 7.0 4.0 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4407 PF14362.6 PRP76555.1 - 2.2 7.5 11.7 1.7 7.9 10.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 PRP76555.1 - 2.4 9.1 22.1 2.2 9.3 0.5 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 PRP76555.1 - 2.4 8.5 18.1 1 9.7 14.7 2.0 1 1 1 2 2 2 0 Fez1 Plasmid_RAQPRD PF09686.10 PRP76555.1 - 3.6 7.9 9.4 9.8 6.5 1.3 3.5 3 1 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF2203 PF09969.9 PRP76555.1 - 4.4 8.1 14.4 2.1 9.1 5.8 3.1 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2203) ComGF PF15980.5 PRP76555.1 - 6.8 7.1 11.5 17 5.8 3.4 3.3 2 1 1 3 3 3 0 Putative Competence protein ComGF LRR_8 PF13855.6 PRP76556.1 - 3e-19 68.5 30.9 7.2e-08 32.1 3.0 6.8 6 1 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 PRP76556.1 - 5.7e-14 52.0 42.4 0.004 17.5 1.4 8.1 5 3 4 9 9 9 8 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP76556.1 - 6.3e-10 39.4 4.3 6.3e-10 39.4 4.3 1.9 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_9 PF14580.6 PRP76556.1 - 0.16 11.4 2.4 1.5 8.3 0.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeat RVT_1 PF00078.27 PRP76557.1 - 8.4e-06 25.4 0.0 2.9e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HxlR PF01638.17 PRP76557.1 - 0.00028 20.7 2.8 0.31 10.9 0.4 3.2 3 0 0 3 3 3 2 HxlR-like helix-turn-helix nos_propeller PF18764.1 PRP76557.1 - 0.0009 19.1 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 2 Nitrous oxide reductase propeller repeat Latrotoxin_C PF15658.6 PRP76557.1 - 0.0061 16.3 0.6 4.4 7.1 0.1 2.6 2 0 0 2 2 2 2 Latrotoxin C-terminal domain CENP-B_N PF04218.13 PRP76557.1 - 0.024 14.2 1.6 13 5.6 0.0 3.5 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain BNIP2 PF12496.8 PRP76557.1 - 0.24 11.8 10.0 0.33 11.4 0.4 3.1 2 1 1 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Ricin_B_lectin PF00652.22 PRP76557.1 - 3.3 8.0 9.2 13 6.0 1.4 2.8 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain Cytochrom_CIII PF02085.16 PRP76557.1 - 4.4 7.7 6.7 24 5.3 0.7 2.6 2 0 0 2 2 2 0 Class III cytochrome C family Tk-SP_N-pro PF18237.1 PRP76558.1 - 0.16 12.1 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Tk-SP N-propeptide domain AAA_22 PF13401.6 PRP76564.1 - 8.8e-05 22.8 0.0 0.00026 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP76564.1 - 0.00015 22.2 0.0 0.00033 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PRP76564.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PRP76564.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PRP76567.1 - 0.00061 20.1 0.0 0.034 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP76567.1 - 0.00084 19.8 0.0 0.46 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PRP76567.1 - 0.0066 16.4 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 PRP76567.1 - 0.06 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 PRP76567.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GerD PF17898.1 PRP76570.1 - 0.0033 17.4 0.3 0.013 15.4 0.3 2.0 1 0 0 1 1 1 1 Spore germination GerD central core domain AAA_35 PF14516.6 PRP76570.1 - 0.019 13.8 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.14 PRP76570.1 - 0.027 13.7 0.0 0.069 12.4 0.0 1.7 2 0 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.6 PRP76570.1 - 0.033 14.5 0.0 0.074 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 PRP76570.1 - 0.035 13.4 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_7 PF12775.7 PRP76570.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 PRP76570.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 PRP76570.1 - 0.14 12.7 0.0 0.52 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 PRP76570.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Helicase AAA PF00004.29 PRP76570.1 - 0.16 12.4 0.0 0.64 10.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PARM PF17061.5 PRP76570.1 - 0.58 10.2 2.8 1.2 9.2 2.8 1.4 1 0 0 1 1 1 0 PARM DUF3824 PF12868.7 PRP76571.1 - 0.06 14.0 2.3 0.086 13.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) GH43_C2 PF17851.1 PRP76573.1 - 0.3 10.8 3.4 0.67 9.6 2.2 1.8 2 0 0 2 2 2 0 Beta xylosidase C-terminal Concanavalin A-like domain DUF5362 PF17319.2 PRP76579.1 - 0.054 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5362) DPM2 PF07297.12 PRP76579.1 - 0.11 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF2157 PF09925.9 PRP76579.1 - 0.11 12.3 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PGG PF13962.6 PRP76579.1 - 0.15 11.9 0.1 0.2 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function End_tail_spike PF12219.8 PRP76579.1 - 0.19 11.7 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase AAA_2 PF07724.14 PRP76580.1 - 9.9e-56 188.5 0.0 3.3e-52 177.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PRP76580.1 - 6.5e-35 119.2 1.4 6.5e-35 119.2 1.4 3.4 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 PRP76580.1 - 1.7e-27 96.5 0.0 1.3e-14 54.8 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PRP76580.1 - 2.7e-21 75.4 1.6 2.7e-21 75.4 1.6 3.6 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PRP76580.1 - 1.8e-18 66.9 0.2 9.5e-12 45.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 PRP76580.1 - 8.9e-17 61.0 7.0 2.5e-08 33.9 0.3 3.8 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 PRP76580.1 - 1.5e-11 44.3 0.0 1.1e-06 28.5 0.0 3.0 2 1 1 3 3 3 2 Sigma-54 interaction domain AAA_22 PF13401.6 PRP76580.1 - 1.1e-10 41.9 1.5 0.00061 20.1 0.0 5.0 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.6 PRP76580.1 - 9.3e-10 39.1 17.5 5.6e-06 26.9 0.1 5.5 4 3 1 5 5 3 2 AAA ATPase domain IstB_IS21 PF01695.17 PRP76580.1 - 6.3e-09 35.8 0.0 0.002 17.9 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 PRP76580.1 - 1.1e-08 35.2 0.1 0.0028 17.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 PRP76580.1 - 5.2e-07 29.4 0.0 0.0078 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 PRP76580.1 - 8.6e-07 28.5 0.3 0.0011 18.4 0.0 3.7 3 1 0 3 3 3 1 Bacterial TniB protein DUF87 PF01935.17 PRP76580.1 - 5.7e-06 26.6 2.7 0.092 12.8 0.0 3.8 3 0 0 3 3 3 1 Helicase HerA, central domain DUF815 PF05673.13 PRP76580.1 - 1.3e-05 24.5 0.5 0.073 12.2 0.0 3.6 4 1 0 4 4 4 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 PRP76580.1 - 4e-05 23.9 3.2 0.6 10.3 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.6 PRP76580.1 - 4.8e-05 24.0 20.2 0.035 14.6 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 PRP76580.1 - 8.1e-05 23.2 2.3 0.15 12.6 0.0 3.6 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.6 PRP76580.1 - 9.7e-05 22.0 0.8 0.029 13.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 PRP76580.1 - 9.9e-05 22.3 0.0 0.13 12.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 PRP76580.1 - 0.00012 21.5 0.3 0.12 11.7 0.0 3.7 3 1 0 3 3 3 1 Zeta toxin Roc PF08477.13 PRP76580.1 - 0.00012 22.2 0.0 0.33 11.2 0.0 3.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 PRP76580.1 - 0.00016 20.8 0.2 0.0012 18.0 0.2 2.4 2 1 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 PRP76580.1 - 0.00018 21.9 0.0 0.68 10.4 0.0 3.1 3 0 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.21 PRP76580.1 - 0.00018 20.9 0.2 1.2 8.5 0.0 3.6 3 1 1 4 4 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 PRP76580.1 - 0.00026 20.8 5.1 0.17 11.6 0.0 4.7 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 PRP76580.1 - 0.00029 20.8 13.0 0.79 9.6 0.2 5.6 5 2 1 7 7 6 2 ATPase domain predominantly from Archaea DNA_pol3_delta2 PF13177.6 PRP76580.1 - 0.00069 19.4 0.0 0.015 15.1 0.0 2.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 PRP76580.1 - 0.0007 19.5 0.9 3 7.7 0.0 4.0 4 0 0 4 4 4 1 RsgA GTPase TsaE PF02367.17 PRP76580.1 - 0.0008 19.4 0.0 2.1 8.4 0.0 3.0 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PRP76580.1 - 0.00081 19.6 0.0 1.1 9.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 PRP76580.1 - 0.00082 19.7 1.2 0.17 12.2 0.1 4.0 3 2 0 4 4 4 1 AAA domain ResIII PF04851.15 PRP76580.1 - 0.0012 18.9 0.0 0.26 11.3 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 PRP76580.1 - 0.0014 17.9 0.3 1.3 8.1 0.0 2.9 3 0 0 3 3 3 1 TIP49 P-loop domain ABC_tran PF00005.27 PRP76580.1 - 0.0017 18.9 3.4 0.27 11.8 0.0 3.8 3 1 0 3 3 3 1 ABC transporter AAA_3 PF07726.11 PRP76580.1 - 0.0032 17.3 0.0 3 7.7 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PRP76580.1 - 0.0039 16.9 0.0 3.3 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PRP76580.1 - 0.0063 16.0 0.0 1.7 8.0 0.0 2.8 2 0 0 2 2 2 1 PhoH-like protein AAA_29 PF13555.6 PRP76580.1 - 0.011 15.4 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain EMP24_GP25L PF01105.24 PRP76580.1 - 0.014 15.3 2.9 0.033 14.1 2.9 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AAA_30 PF13604.6 PRP76580.1 - 0.016 14.9 0.0 1.4 8.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 PRP76580.1 - 0.051 12.9 0.0 4 6.7 0.1 2.8 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 SRP54 PF00448.22 PRP76580.1 - 0.061 13.0 0.0 6.2 6.4 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FTA4 PF13093.6 PRP76580.1 - 0.11 12.4 7.4 0.24 11.3 7.4 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Parvo_NS1 PF01057.17 PRP76580.1 - 0.13 11.4 0.0 6.2 5.8 0.0 2.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CbiA PF01656.23 PRP76580.1 - 0.15 12.1 0.4 6.6 6.8 0.0 3.5 2 2 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE_N PF05157.15 PRP76580.1 - 0.25 11.6 2.3 2.4 8.4 0.0 3.5 4 0 0 4 4 3 0 Type II secretion system (T2SS), protein E, N-terminal domain AAA_11 PF13086.6 PRP76580.1 - 0.79 9.4 10.2 8.2 6.1 0.0 3.3 2 1 0 3 3 3 0 AAA domain Rx_N PF18052.1 PRP76580.1 - 3.7 7.9 10.3 67 3.8 5.7 3.7 2 1 1 3 3 3 0 Rx N-terminal domain Atg14 PF10186.9 PRP76580.1 - 5.3 6.0 12.5 9.1 5.3 12.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Response_reg PF00072.24 PRP76581.1 - 2.5e-19 69.5 0.2 7.6e-19 67.9 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 PRP76581.1 - 2.6e-18 66.6 0.0 5.6e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP76581.1 - 4.4e-12 45.9 2.4 4.7e-12 45.8 0.0 2.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain MASE3 PF17159.4 PRP76581.1 - 2.6e-11 43.6 22.9 4.4e-11 42.8 22.9 1.4 1 0 0 1 1 1 1 Membrane-associated sensor domain PAS PF00989.25 PRP76581.1 - 0.051 13.6 0.0 0.41 10.7 0.0 2.4 2 0 0 2 2 2 0 PAS fold Pkinase PF00069.25 PRP76582.1 - 3.5e-57 193.8 0.0 1.2e-56 192.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76582.1 - 1.9e-31 109.3 0.0 1.6e-24 86.6 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP76582.1 - 5.2e-09 35.8 0.0 2.6e-05 23.7 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 PRP76582.1 - 9e-05 22.5 0.0 0.027 14.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP76582.1 - 9.8e-05 21.3 0.0 0.00043 19.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP76582.1 - 0.0015 17.9 0.0 0.0027 17.1 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PRP76582.1 - 0.0068 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 PRP76582.1 - 0.0092 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family PIP49_C PF12260.8 PRP76582.1 - 0.02 14.5 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 FTA2 PF13095.6 PRP76582.1 - 0.024 14.3 0.1 0.11 12.1 0.0 2.1 1 1 2 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PRP76582.1 - 0.032 13.2 0.0 0.092 11.7 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain DUF473 PF04322.12 PRP76582.1 - 0.075 12.9 0.1 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF473) Asp-B-Hydro_N PF05279.11 PRP76584.1 - 0.69 9.9 11.1 0.055 13.5 6.5 1.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Sec62 PF03839.16 PRP76584.1 - 5.8 6.4 6.2 9 5.7 6.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 HTH_Tnp_4 PF13613.6 PRP76585.1 - 2.7e-08 33.4 0.1 5.4e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_4 PF13359.6 PRP76585.1 - 2.2e-07 30.7 0.0 7.2e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_50 PF18024.1 PRP76585.1 - 0.0042 16.6 0.0 0.017 14.7 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_36 PF13730.6 PRP76585.1 - 0.04 13.9 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain RXLR_WY PF18634.1 PRP76585.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 RXLR phytopathogen effector protein WY-domain Patatin PF01734.22 PRP76587.1 - 0.32 11.2 3.2 1.1 9.5 3.1 2.0 1 1 0 1 1 1 0 Patatin-like phospholipase DegS PF05384.11 PRP76588.1 - 0.00069 19.1 1.6 0.00085 18.9 0.1 1.9 2 0 0 2 2 2 1 Sensor protein DegS HD_3 PF13023.6 PRP76588.1 - 0.16 11.8 0.8 0.37 10.7 0.8 1.5 1 0 0 1 1 1 0 HD domain Alpha-amylase PF00128.24 PRP76589.1 - 2.7e-16 60.0 0.0 1.2e-15 58.0 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PRP76589.1 - 2.2e-11 44.0 0.2 7.7e-11 42.3 0.2 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Pur_ac_phosph_N PF16656.5 PRP76589.1 - 0.46 11.1 4.7 0.56 10.8 0.0 3.1 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Inhibitor_Mig-6 PF11555.8 PRP76589.1 - 1.5 9.0 5.5 4.5 7.5 5.5 1.8 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 DUF1284 PF06935.11 PRP76590.1 - 0.6 10.6 3.4 0.62 10.5 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1284) zf-MYND PF01753.18 PRP76591.1 - 5.2e-11 42.5 16.7 1.3e-10 41.2 16.7 1.7 1 0 0 1 1 1 1 MYND finger CN_hydrolase PF00795.22 PRP76592.1 - 2.4e-55 187.7 0.0 2.9e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase RhoGEF PF00621.20 PRP76593.1 - 1.3e-44 152.6 0.2 2.4e-44 151.8 0.2 1.5 1 0 0 1 1 1 1 RhoGEF domain MORN PF02493.20 PRP76593.1 - 5.6e-44 145.5 83.6 5.1e-05 22.9 2.7 17.6 18 0 0 18 18 18 12 MORN repeat zf-RING_2 PF13639.6 PRP76593.1 - 4.8e-09 36.4 5.5 1.1e-08 35.2 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PRP76593.1 - 7.9e-07 28.7 1.1 1.8e-06 27.6 1.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PRP76593.1 - 1.4e-05 24.8 4.3 3.4e-05 23.6 4.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP76593.1 - 2.2e-05 24.7 3.1 5.4e-05 23.4 3.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PRP76593.1 - 4.6e-05 23.2 1.5 0.0001 22.1 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP76593.1 - 0.00015 21.7 2.0 0.00037 20.5 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger PH PF00169.29 PRP76593.1 - 0.0066 17.0 0.0 0.02 15.4 0.0 1.9 1 0 0 1 1 1 1 PH domain zf-RING_5 PF14634.6 PRP76593.1 - 0.012 15.6 4.0 0.031 14.2 4.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PRP76593.1 - 0.039 13.6 3.4 0.078 12.6 3.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 PRP76593.1 - 0.046 13.9 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family zf-ANAPC11 PF12861.7 PRP76593.1 - 1.3 9.2 4.0 5.7 7.1 4.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PRP76593.1 - 1.5 8.8 3.6 3 7.8 3.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 PRP76593.1 - 1.6 9.0 5.5 3.8 7.8 5.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Ras PF00071.22 PRP76595.1 - 8.4e-56 188.0 0.0 9.8e-56 187.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP76595.1 - 4.6e-35 120.4 0.1 1.7e-34 118.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP76595.1 - 6e-12 45.4 0.1 7.3e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP76595.1 - 0.0019 17.6 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP76595.1 - 0.0032 17.5 0.0 0.0051 16.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP76595.1 - 0.0097 15.8 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 PRP76595.1 - 0.026 14.0 0.0 0.048 13.1 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 PRP76595.1 - 0.035 13.4 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Septin APP_N PF02177.16 PRP76595.1 - 0.087 13.2 0.0 4.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding PPR_2 PF13041.6 PRP76596.1 - 2.8e-31 107.5 15.3 3.9e-12 46.2 0.5 4.1 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.6 PRP76596.1 - 7.1e-22 77.3 7.0 1.7e-07 31.2 0.5 4.2 3 1 0 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 PRP76596.1 - 7.6e-16 57.5 5.9 0.039 13.6 0.0 6.5 6 0 0 6 6 6 6 PPR repeat PPR_long PF17177.4 PRP76596.1 - 2.8e-09 36.6 0.1 0.00016 21.1 0.0 2.9 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 PRP76596.1 - 1.8e-05 23.9 1.7 0.086 11.9 0.1 4.0 1 1 1 2 2 2 2 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.11 PRP76596.1 - 0.00018 21.9 0.9 1.7 9.1 0.1 4.0 2 2 2 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) PPR PF01535.20 PRP76596.1 - 0.00022 21.3 0.5 0.00022 21.3 0.5 6.3 6 0 0 6 6 6 1 PPR repeat MRP-S27 PF10037.9 PRP76596.1 - 0.0018 17.2 0.4 0.85 8.4 0.1 2.7 2 1 1 3 3 3 2 Mitochondrial 28S ribosomal protein S27 Polysacc_deac_1 PF01522.21 PRP76596.1 - 0.033 14.1 0.0 0.065 13.1 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide deacetylase Terminase_4 PF05119.12 PRP76596.1 - 0.071 13.5 0.4 4.4 7.8 0.2 2.7 3 0 0 3 3 3 0 Phage terminase, small subunit Holin_9 PF16936.5 PRP76596.1 - 0.1 12.8 0.1 9.5 6.5 0.1 2.7 2 0 0 2 2 2 0 Putative holin PolyA_pol_RNAbd PF12627.7 PRP76596.1 - 0.18 11.6 0.1 0.45 10.3 0.1 1.6 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Pkinase_Tyr PF07714.17 PRP76598.1 - 1.4e-64 217.9 0.0 2.6e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76598.1 - 1.1e-36 126.5 0.0 2.8e-36 125.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP76598.1 - 6.8e-33 112.2 72.5 2.8e-05 24.4 1.5 14.2 6 3 10 17 17 17 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP76598.1 - 2e-32 110.7 65.4 7.3e-09 35.3 2.4 11.2 7 2 5 13 13 13 10 Leucine rich repeat LRR_6 PF13516.6 PRP76598.1 - 3.3e-13 48.5 42.2 1.1 9.4 0.0 18.0 19 0 0 19 19 19 3 Leucine Rich repeat LRR_1 PF00560.33 PRP76598.1 - 3.6e-07 29.8 63.0 6.8 7.7 0.0 18.9 21 0 0 21 21 19 3 Leucine Rich Repeat zf-C3HC4_2 PF13923.6 PRP76598.1 - 4.4e-06 26.4 12.9 1.4e-05 24.8 12.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP76598.1 - 4.4e-05 23.3 8.0 4.4e-05 23.3 8.0 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP76598.1 - 0.00017 21.4 13.0 0.00045 20.0 13.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP76598.1 - 0.0005 19.9 10.3 0.0016 18.3 10.3 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PRP76598.1 - 0.00067 19.9 12.8 0.0021 18.4 12.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PRP76598.1 - 0.013 15.5 12.7 0.039 14.0 12.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 PRP76598.1 - 0.014 15.6 6.1 0.037 14.3 6.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PRP76598.1 - 0.019 15.1 13.9 0.076 13.2 13.9 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LRR_9 PF14580.6 PRP76598.1 - 0.029 13.9 15.3 0.18 11.3 1.9 4.8 2 1 3 5 5 5 0 Leucine-rich repeat DUF3760 PF12586.8 PRP76598.1 - 1.1 9.4 3.5 11 6.2 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3760) Synaptobrevin PF00957.21 PRP76599.1 - 1.1e-09 37.9 2.8 1.9e-09 37.2 2.8 1.4 1 0 0 1 1 1 1 Synaptobrevin Cytokin_check_N PF10407.9 PRP76599.1 - 0.079 12.9 1.0 1.1 9.3 0.6 2.1 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus DUF5056 PF16479.5 PRP76602.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) JmjC PF02373.22 PRP76603.1 - 0.017 15.5 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF2406 PF10295.9 PRP76603.1 - 0.037 14.7 0.1 0.11 13.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) zf-Sec23_Sec24 PF04810.15 PRP76603.1 - 0.3 11.2 3.1 0.28 11.2 1.4 1.8 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger F-box PF00646.33 PRP76604.1 - 0.031 14.1 0.6 0.061 13.2 0.6 1.5 1 0 0 1 1 1 0 F-box domain UCH PF00443.29 PRP76608.1 - 4.6e-06 26.3 2.9 1.2e-05 24.9 0.1 2.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase C4 PF01413.19 PRP76608.1 - 0.051 14.0 1.9 0.12 12.8 1.9 1.6 1 0 0 1 1 1 0 C-terminal tandem repeated domain in type 4 procollagen UCH_1 PF13423.6 PRP76608.1 - 0.24 10.9 2.8 9 5.8 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF4652 PF15525.6 PRP76609.1 - 0.063 13.1 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4652) Pkinase PF00069.25 PRP76610.1 - 3.4e-27 95.5 0.6 1e-25 90.6 0.2 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76610.1 - 5e-13 48.9 0.0 3.7e-11 42.8 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase TrmO_C PF18389.1 PRP76610.1 - 0.068 13.3 0.2 0.74 10.0 0.1 2.6 2 1 0 2 2 2 0 TrmO C-terminal domain Herpes_BTRF1 PF04682.12 PRP76610.1 - 0.17 11.2 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region zf-C3Hc3H PF13891.6 PRP76621.1 - 0.027 14.8 0.2 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Potential DNA-binding domain Aconitase PF00330.20 PRP76623.1 - 5.2e-150 500.5 0.1 6.4e-150 500.2 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 PRP76623.1 - 8e-47 158.8 0.2 3.5e-46 156.8 0.1 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain ADH_N_2 PF16884.5 PRP76625.1 - 9.2e-22 77.0 0.0 2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 PRP76625.1 - 9.7e-20 70.9 0.0 1.7e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP76625.1 - 0.0047 18.0 0.0 0.025 15.6 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 PRP76625.1 - 0.025 14.4 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DTHCT PF08070.11 PRP76626.1 - 0.64 10.8 37.8 0.22 12.3 10.1 3.8 3 0 0 3 3 3 0 DTHCT (NUC029) region WD40 PF00400.32 PRP76628.1 - 4.6e-14 52.6 5.4 0.085 13.8 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76628.1 - 3.6e-05 24.0 1.0 8.1 6.8 0.0 5.4 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 PRP76628.1 - 0.067 12.5 0.4 5.2 6.3 0.0 2.6 2 1 0 2 2 2 0 CPSF A subunit region DNA_pol_B PF00136.21 PRP76629.1 - 0.14 10.8 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase family B HNH_2 PF13391.6 PRP76631.1 - 2e-21 75.9 0.0 3.8e-10 39.8 0.0 2.8 2 0 0 2 2 2 2 HNH endonuclease Cu_bind_CorA PF18252.1 PRP76631.1 - 0.086 12.5 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Copper(I)-binding protein CorA FerI PF08151.12 PRP76631.1 - 0.12 12.5 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 FerI (NUC094) domain GTPase_binding PF09027.10 PRP76633.1 - 0.046 13.7 0.0 0.049 13.6 0.0 1.1 1 0 0 1 1 1 0 GTPase binding SYCE1 PF15233.6 PRP76634.1 - 0.045 13.8 0.6 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Ras PF00071.22 PRP76635.1 - 3.2e-62 208.9 1.0 1.1e-61 207.2 0.2 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP76635.1 - 1.6e-35 121.9 0.2 3.6e-35 120.8 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP76635.1 - 2.2e-17 63.1 0.0 5.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Ydr279_N PF17745.1 PRP76635.1 - 6e-10 39.2 0.2 8.9e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 PRP76635.1 - 7.5e-06 26.2 0.4 4.2e-05 23.8 0.3 2.1 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain GTP_EFTU PF00009.27 PRP76635.1 - 1.3e-05 24.8 0.5 5.9e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP76635.1 - 7e-05 22.9 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP76635.1 - 8.6e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PRP76635.1 - 0.0003 20.3 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PRP76635.1 - 0.0043 17.0 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 PRP76635.1 - 0.052 14.0 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP76635.1 - 0.057 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PRP76635.1 - 0.07 13.6 0.9 0.19 12.3 0.0 2.1 3 0 0 3 3 2 0 ABC transporter AAA_29 PF13555.6 PRP76635.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ENTH PF01417.20 PRP76636.1 - 1.9e-39 134.5 0.0 2.9e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 PRP76636.1 - 2.1e-05 23.7 0.0 2.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 ANTH domain NKAIN PF05640.14 PRP76637.1 - 0.0062 15.8 5.9 0.0062 15.8 5.9 1.7 1 1 1 2 2 2 1 Na,K-Atpase Interacting protein SafA PF17073.5 PRP76637.1 - 0.031 14.2 2.2 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Two-component-system connector protein DHHC PF01529.20 PRP76637.1 - 0.14 12.2 3.2 0.28 11.3 3.2 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase CLTH PF10607.9 PRP76638.1 - 1.3e-32 112.7 0.8 1.3e-32 112.7 0.8 2.3 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PRP76638.1 - 6.6e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 LisH Myb_DNA-bind_3 PF12776.7 PRP76638.1 - 0.016 16.2 5.5 0.071 14.1 0.9 3.2 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Baculo_PEP_C PF04513.12 PRP76638.1 - 0.049 13.7 0.8 0.23 11.5 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mig-14 PF07395.11 PRP76638.1 - 0.053 12.9 2.1 0.35 10.2 0.3 2.2 1 1 1 2 2 2 0 Mig-14 NPV_P10 PF05531.12 PRP76638.1 - 0.1 13.1 1.3 0.42 11.1 1.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_S7 PF00949.21 PRP76638.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease ApoC-I PF04691.12 PRP76638.1 - 0.12 12.3 1.1 0.62 10.0 0.2 2.5 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) T3SchapCesA PF11439.8 PRP76638.1 - 0.22 11.7 2.3 1.2 9.3 0.7 2.7 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA DUF1664 PF07889.12 PRP76638.1 - 0.81 9.7 8.1 0.18 11.8 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 PRP76638.1 - 2.4 8.2 10.5 7.6 6.6 10.5 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 PRP76638.1 - 3.8 6.7 8.4 0.69 9.1 4.1 1.8 2 0 0 2 2 2 0 TMPIT-like protein MCU PF04678.13 PRP76638.1 - 3.9 7.6 6.3 1 9.4 1.9 2.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter GvpL_GvpF PF06386.11 PRP76638.1 - 3.9 7.3 6.2 6.7 6.6 6.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Tho2 PF11262.8 PRP76638.1 - 5.1 6.2 13.7 0.37 9.9 6.9 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Fzo_mitofusin PF04799.13 PRP76638.1 - 7 6.2 9.2 0.53 9.8 3.0 2.2 2 1 1 3 3 3 0 fzo-like conserved region DUF2951 PF11166.8 PRP76638.1 - 7.1 6.9 10.4 44 4.4 6.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Cpn60_TCP1 PF00118.24 PRP76639.1 - 8.4e-52 176.4 3.9 3.3e-51 174.4 3.9 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DS PF01916.17 PRP76641.1 - 1.9e-130 434.3 0.0 2.3e-130 434.1 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase LEA_4 PF02987.16 PRP76642.1 - 0.011 15.8 14.7 0.11 12.7 14.7 2.5 1 1 0 1 1 1 0 Late embryogenesis abundant protein DUF3619 PF12279.8 PRP76642.1 - 0.38 11.1 4.0 0.85 10.0 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) DUF883 PF05957.13 PRP76642.1 - 0.82 10.3 10.1 2.7 8.7 9.7 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Dehydrin PF00257.19 PRP76642.1 - 3.8 8.1 7.3 0.54 10.8 2.7 1.9 2 1 0 2 2 2 0 Dehydrin PQ-loop PF04193.14 PRP76644.1 - 7.3e-25 86.5 3.4 7.7e-14 51.2 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 PRP76644.1 - 0.066 13.3 4.2 3.2 7.9 0.2 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF1600 PF07667.11 PRP76644.1 - 0.34 11.1 10.5 0.095 12.9 1.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1600) TetR_C_17 PF17922.1 PRP76647.1 - 0.1 12.7 1.2 0.18 11.9 1.2 1.5 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain rve PF00665.26 PRP76648.1 - 0.0026 17.9 0.0 0.0051 17.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Glyco_hydro_57 PF03065.15 PRP76648.1 - 0.011 15.0 0.2 0.012 14.8 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 SF3A2 PF16835.5 PRP76648.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF3232 PF11554.8 PRP76648.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3232) Med13_C PF06333.12 PRP76650.1 - 1.8e-18 66.9 0.2 1.8e-18 66.9 0.2 4.4 4 1 1 5 5 5 2 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 PRP76650.1 - 2.6e-17 63.4 0.9 2.2e-11 44.0 0.0 4.4 4 1 0 4 4 4 2 MID domain of medPIWI DNA_methylase PF00145.17 PRP76651.1 - 9.2e-29 100.8 0.0 8.4e-26 91.1 0.0 2.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF1712 PF08217.11 PRP76652.1 - 2.9e-58 197.8 7.9 4e-53 180.9 1.5 2.2 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) Homoserine_dh PF00742.19 PRP76652.1 - 7.3e-49 166.0 0.0 3.1e-48 164.0 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase AA_kinase PF00696.28 PRP76652.1 - 6.1e-39 134.1 0.3 2.3e-38 132.2 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family NAD_binding_3 PF03447.16 PRP76652.1 - 4.2e-21 75.8 0.0 1.2e-20 74.4 0.0 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 PRP76652.1 - 1.6e-13 50.2 0.6 6.4e-06 25.8 0.1 3.1 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 PRP76652.1 - 7.4e-09 35.3 3.5 0.00037 20.2 0.4 2.7 2 0 0 2 2 2 2 ACT domain ACT_6 PF13740.6 PRP76652.1 - 0.033 14.2 1.1 7.4 6.6 0.1 3.1 1 1 1 2 2 2 0 ACT domain DUF2935 PF11155.8 PRP76652.1 - 0.038 14.3 0.0 5.6 7.3 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) Sdh5 PF03937.16 PRP76652.1 - 0.047 13.7 0.6 9.1 6.3 0.0 2.9 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase PAC2 PF09754.9 PRP76652.1 - 0.092 12.7 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 PAC2 family DapB_N PF01113.20 PRP76652.1 - 0.14 12.3 0.5 1 9.5 0.0 2.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus LAG1-DNAbind PF09271.11 PRP76656.1 - 0.0058 17.3 0.0 0.011 16.4 0.0 1.6 1 1 0 1 1 1 1 LAG1, DNA binding ADH_zinc_N PF00107.26 PRP76657.1 - 1.1e-08 35.1 0.1 2.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP76657.1 - 3.2e-07 30.2 0.0 9.3e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PRP76657.1 - 0.0017 19.4 0.0 0.004 18.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YEATS PF03366.16 PRP76658.1 - 1.3e-21 76.3 0.2 4.5e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 YEATS family ABC_tran PF00005.27 PRP76659.1 - 2e-26 93.1 0.0 3.6e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP76659.1 - 3.3e-19 69.2 16.7 1.2e-18 67.3 16.7 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP76659.1 - 1.5e-12 47.9 0.1 1.7e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PRP76659.1 - 0.00021 21.8 0.0 0.00043 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 PRP76659.1 - 0.0028 17.0 0.1 0.49 9.7 0.0 2.2 2 0 0 2 2 2 2 Zeta toxin ABC2_membrane PF01061.24 PRP76659.1 - 0.0036 16.7 29.1 0.051 13.0 20.7 2.9 3 0 0 3 3 3 2 ABC-2 type transporter RsgA_GTPase PF03193.16 PRP76659.1 - 0.0038 17.1 0.1 0.0073 16.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 PRP76659.1 - 0.012 15.7 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 PRP76659.1 - 0.016 15.7 0.6 0.027 15.0 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP76659.1 - 0.032 14.0 0.2 0.13 12.0 0.2 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 PRP76659.1 - 0.17 11.3 0.1 19 4.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 PRP76660.1 - 7.8e-28 97.7 0.0 1.8e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP76660.1 - 1.2e-27 96.9 24.2 3.4e-27 95.5 20.5 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP76660.1 - 2.1e-07 31.0 0.1 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 PRP76660.1 - 0.003 18.2 0.2 0.01 16.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) ABC2_membrane PF01061.24 PRP76660.1 - 0.004 16.6 22.1 0.004 16.6 22.1 2.9 3 0 0 3 3 3 1 ABC-2 type transporter AAA_29 PF13555.6 PRP76660.1 - 0.064 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 PRP76660.1 - 0.11 11.9 0.0 0.78 9.1 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 PRP76660.1 - 0.19 11.4 0.1 1.1 9.0 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein DSPc PF00782.20 PRP76663.1 - 2.6e-09 37.0 0.0 5.2e-09 36.0 0.0 1.5 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP76663.1 - 6.5e-05 22.6 0.0 0.00019 21.1 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 PRP76663.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 PRP76663.1 - 0.033 14.3 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PRP76663.1 - 0.2 11.6 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Trs65 PF12735.7 PRP76664.1 - 8.4e-13 48.4 0.0 4.5e-12 46.0 0.0 1.9 1 1 0 2 2 2 1 TRAPP trafficking subunit Trs65 MP PF01107.18 PRP76664.1 - 0.039 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Viral movement protein (MP) COX6B PF02297.17 PRP76665.1 - 0.051 13.8 0.7 0.074 13.3 0.7 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 PRP76665.1 - 0.11 12.8 2.6 0.19 12.0 2.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) CX9C PF16860.5 PRP76665.1 - 0.19 11.8 2.8 0.89 9.6 0.2 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF3128 PF11326.8 PRP76665.1 - 0.61 10.5 3.4 4.9 7.6 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) MoCF_biosynth PF00994.24 PRP76666.1 - 2e-32 111.9 0.0 2.4e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF2865 PF11064.8 PRP76667.1 - 0.012 16.0 0.3 0.013 15.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2865) UPF0193 PF05250.11 PRP76667.1 - 0.027 14.3 0.6 0.032 14.0 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) AMPK1_CBM PF16561.5 PRP76669.1 - 1.4e-10 41.2 0.2 2.6e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Chromo PF00385.24 PRP76670.1 - 3.7e-11 42.8 0.0 6.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Spore_coat_CotO PF14153.6 PRP76670.1 - 1.4 8.8 7.2 2.5 8.0 7.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Integrase_H2C2 PF17921.1 PRP76671.1 - 3.3e-22 78.4 1.1 3.3e-22 78.4 1.1 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PRP76671.1 - 2.8e-07 30.6 0.1 5.4e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 H2C2 zinc finger rve PF00665.26 PRP76671.1 - 4.3e-05 23.7 0.3 0.93 9.7 0.0 3.5 2 2 1 3 3 3 2 Integrase core domain Ferrochelatase PF00762.19 PRP76671.1 - 0.15 11.1 0.0 4.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Ferrochelatase SapB_2 PF03489.17 PRP76672.1 - 0.00033 20.7 0.1 0.00075 19.5 0.1 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 2 DUF4690 PF15756.5 PRP76672.1 - 0.0005 20.6 0.4 0.0005 20.6 0.4 2.2 2 0 0 2 2 2 1 Small Novel Rich in Cartilage BB_PF PF18063.1 PRP76672.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Beta barrel Pore-forming domain EB PF01683.18 PRP76672.1 - 0.5 10.7 5.3 0.14 12.5 1.3 2.1 2 0 0 2 2 2 0 EB module EGF_2 PF07974.13 PRP76672.1 - 0.88 10.0 16.3 0.35 11.3 9.9 2.6 2 0 0 2 2 2 0 EGF-like domain Clathrin PF00637.20 PRP76673.1 - 9.7e-192 628.5 43.5 9.7e-32 109.8 2.2 8.7 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 PRP76673.1 - 9.6e-33 111.9 1.1 9.6e-33 111.9 1.1 3.7 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 PRP76673.1 - 3.8e-28 96.4 0.6 2.4e-06 27.6 0.0 5.6 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.10 PRP76673.1 - 1.4e-11 43.6 2.5 3.7e-11 42.2 1.2 2.4 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_14 PF13428.6 PRP76673.1 - 2.3e-08 34.2 0.5 3 8.9 0.0 8.3 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP76673.1 - 1.8e-07 30.7 2.5 3.2 8.0 0.1 7.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP76673.1 - 3.9e-05 23.5 5.0 0.33 11.3 0.1 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP76673.1 - 0.003 17.3 2.8 6.2 6.8 0.2 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 PRP76673.1 - 0.0054 15.8 6.4 0.11 11.6 0.3 4.4 5 0 0 5 5 5 1 Coatomer WD associated region DUF3856 PF12968.7 PRP76673.1 - 0.048 13.7 0.1 0.23 11.5 0.1 2.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 PRP76673.1 - 0.059 13.7 0.4 8.1 6.8 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat RNA_binding PF01877.17 PRP76673.1 - 0.31 11.3 4.2 7.5 6.9 0.1 3.2 3 0 0 3 3 2 0 RNA binding TPR_2 PF07719.17 PRP76673.1 - 0.33 11.2 10.8 2 8.8 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat YppF PF14178.6 PRP76673.1 - 0.41 10.6 3.0 13 5.8 0.4 3.2 2 0 0 2 2 2 0 YppF-like protein RRM_1 PF00076.22 PRP76674.1 - 5.5e-47 157.5 0.6 9.8e-22 76.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 PRP76674.1 - 1.9e-14 54.5 6.3 9.5e-07 29.8 0.1 3.3 2 1 1 3 3 3 2 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 PRP76674.1 - 6.9e-09 35.4 0.0 0.0011 18.8 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 PRP76674.1 - 3e-05 24.1 0.0 0.024 14.8 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 PRP76674.1 - 0.00068 19.6 0.2 0.033 14.2 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 PRP76674.1 - 0.00094 19.1 0.1 4.5 7.3 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 PRP76674.1 - 0.0036 17.4 0.1 0.11 12.6 0.0 3.1 3 1 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 PRP76674.1 - 0.013 15.1 0.0 0.11 12.1 0.0 2.2 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 PRP76674.1 - 0.029 14.3 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 RL domain DUF1866 PF08952.11 PRP76674.1 - 0.057 13.3 0.0 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) SPO11_like PF03533.14 PRP76674.1 - 0.079 13.1 0.1 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 SPO11 homologue SET_assoc PF11767.8 PRP76674.1 - 0.085 12.5 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Ribosomal_60s PF00428.19 PRP76674.1 - 0.14 12.8 3.1 0.45 11.1 3.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein AAA PF00004.29 PRP76677.1 - 2.8e-62 209.0 0.0 1.9e-45 154.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP76677.1 - 2.7e-07 31.1 0.0 0.012 16.0 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain RuvB_N PF05496.12 PRP76677.1 - 3.5e-06 26.9 0.2 0.00015 21.5 0.0 3.4 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 PRP76677.1 - 2.9e-05 24.0 0.1 0.015 15.2 0.0 3.5 4 1 0 4 4 3 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 PRP76677.1 - 0.00071 20.1 0.2 0.093 13.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 PRP76677.1 - 0.0014 18.7 0.1 0.018 15.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 PRP76677.1 - 0.0026 17.5 0.1 0.0083 15.9 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PRP76677.1 - 0.0029 17.9 0.0 0.024 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP76677.1 - 0.0041 17.5 0.0 0.026 14.9 0.0 2.2 2 0 0 2 2 2 1 RNA helicase ATPase PF06745.13 PRP76677.1 - 0.0056 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 PRP76677.1 - 0.0056 16.7 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PRP76677.1 - 0.0058 16.8 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 PRP76677.1 - 0.0073 16.4 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 PRP76677.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 PRP76677.1 - 0.012 15.6 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 PRP76677.1 - 0.013 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 PRP76677.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 PRP76677.1 - 0.015 14.4 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 PRP76677.1 - 0.025 14.0 0.1 0.068 12.5 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SKI PF01202.22 PRP76677.1 - 0.043 14.0 0.0 8.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_25 PF13481.6 PRP76677.1 - 0.053 13.1 0.2 1.1 8.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 PRP76677.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 PRP76677.1 - 0.074 12.8 0.0 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 PRP76677.1 - 0.1 13.0 0.0 0.58 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PRP76677.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.11 PRP76677.1 - 0.16 11.8 0.0 0.51 10.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PRP76677.1 - 0.18 11.5 0.0 0.38 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 PRP76680.1 - 5.5e-47 157.5 0.6 9.8e-22 76.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 PRP76680.1 - 1.9e-14 54.5 6.3 9.5e-07 29.8 0.1 3.3 2 1 1 3 3 3 2 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 PRP76680.1 - 6.9e-09 35.4 0.0 0.0011 18.8 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 PRP76680.1 - 3e-05 24.1 0.0 0.024 14.8 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 PRP76680.1 - 0.00068 19.6 0.2 0.033 14.2 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 PRP76680.1 - 0.00094 19.1 0.1 4.5 7.3 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 PRP76680.1 - 0.0036 17.4 0.1 0.11 12.6 0.0 3.1 3 1 0 3 3 3 1 Limkain b1 RRM_5 PF13893.6 PRP76680.1 - 0.013 15.1 0.0 0.11 12.1 0.0 2.2 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 PRP76680.1 - 0.029 14.3 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 RL domain DUF1866 PF08952.11 PRP76680.1 - 0.057 13.3 0.0 1.3 8.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) SPO11_like PF03533.14 PRP76680.1 - 0.079 13.1 0.1 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 SPO11 homologue SET_assoc PF11767.8 PRP76680.1 - 0.085 12.5 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Ribosomal_60s PF00428.19 PRP76680.1 - 0.14 12.8 3.1 0.45 11.1 3.1 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein Clathrin_propel PF01394.20 PRP76681.1 - 2.9e-18 65.2 0.2 1.8e-07 31.1 0.0 3.3 3 0 0 3 3 3 3 Clathrin propeller repeat Trp_leader2 PF08056.11 PRP76681.1 - 0.059 13.4 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Tryptophan operon leader peptide GIDA PF01134.22 PRP76682.1 - 5.2e-135 450.5 0.0 8e-134 446.6 0.0 2.1 1 1 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 PRP76682.1 - 2.1e-65 220.8 0.1 3.1e-65 220.3 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 PRP76682.1 - 3e-08 33.5 0.1 6.1e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP76682.1 - 1.3e-05 24.6 1.6 4.2e-05 22.9 1.5 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP76682.1 - 4.6e-05 22.7 2.0 5.4e-05 22.5 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 PRP76682.1 - 0.00088 18.6 0.3 0.0017 17.7 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 PRP76682.1 - 0.0073 15.6 0.0 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PRP76682.1 - 0.0074 15.4 0.5 0.069 12.2 0.3 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 PRP76682.1 - 0.014 15.9 1.4 0.025 15.1 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP76682.1 - 0.05 12.3 3.0 0.11 11.2 1.5 2.2 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 PRP76682.1 - 0.11 11.7 0.3 0.17 11.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain UPF0254 PF06787.11 PRP76683.1 - 0.14 12.0 0.0 0.48 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0254) Pkinase_Tyr PF07714.17 PRP76685.1 - 3.4e-72 242.8 0.0 4.8e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76685.1 - 2.1e-48 165.0 0.0 3.3e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Beta_helix PF13229.6 PRP76685.1 - 1.6e-07 31.3 153.7 4.4e-07 29.9 10.3 7.8 2 2 4 6 6 6 4 Right handed beta helix region FTP PF07504.13 PRP76685.1 - 0.084 12.7 1.0 5.7 6.9 0.1 3.2 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif Insulin_TMD PF17870.1 PRP76685.1 - 0.14 12.3 1.9 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Kdo PF06293.14 PRP76685.1 - 0.25 10.7 0.0 0.4 10.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Esterase_phd PF10503.9 PRP76686.1 - 5.9e-06 25.9 0.1 1.7e-05 24.4 0.1 1.7 1 1 1 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 PRP76686.1 - 8.9e-05 22.1 0.6 0.00044 19.8 0.4 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family Gon7 PF08738.10 PRP76687.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 Gon7 family LBP_BPI_CETP_C PF02886.17 PRP76688.1 - 1.5e-32 112.9 0.1 7.1e-31 107.5 0.0 2.2 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 PRP76688.1 - 8.5e-11 41.7 0.4 1.9e-10 40.6 0.4 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain CNPase PF05881.12 PRP76692.1 - 0.094 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) DAO PF01266.24 PRP76693.1 - 1.2e-12 48.2 0.3 6.3e-11 42.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 PRP76693.1 - 0.16 11.2 0.1 0.25 10.6 0.1 1.2 1 0 0 1 1 1 0 Thi4 family Ribosomal_L27 PF01016.19 PRP76694.1 - 3.5e-12 46.2 0.1 6.4e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein TPH PF13868.6 PRP76695.1 - 4.4e-05 22.2 131.7 4.4e-05 22.2 131.7 3.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RCC1 PF00415.18 PRP76697.1 - 6.9e-47 157.9 7.9 2.3e-12 47.4 0.0 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP76697.1 - 8.8e-24 82.7 22.2 1.1e-09 37.8 0.3 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 PRP76697.1 - 5.8e-08 32.4 0.2 9e-08 31.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76697.1 - 0.0038 16.5 0.1 0.0061 15.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Adaptin_N PF01602.20 PRP76697.1 - 0.039 12.5 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Hira PF07569.11 PRP76697.1 - 0.098 12.4 0.0 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split Radical_SAM PF04055.21 PRP76698.1 - 6.8e-10 39.6 0.0 1.8e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily PUB PF09409.10 PRP76698.1 - 0.041 13.8 0.2 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 PUB domain UMP1 PF05348.11 PRP76698.1 - 0.079 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 GFD1 PF17331.2 PRP76698.1 - 2.6 8.3 5.2 3.8 7.8 1.5 2.5 2 0 0 2 2 2 0 GFD1 mRNA transport factor Telomerase_RBD PF12009.8 PRP76699.1 - 0.0082 16.2 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RhoGAP PF00620.27 PRP76700.1 - 9.7e-42 142.4 0.0 1.7e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain SH3_1 PF00018.28 PRP76700.1 - 4.3e-16 58.3 0.0 9.1e-16 57.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP76700.1 - 3.4e-13 49.2 0.0 7.1e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP76700.1 - 5.3e-12 45.2 0.0 1.1e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 PRP76700.1 - 6.6e-11 42.6 0.1 1.4e-10 41.6 0.1 1.6 1 0 0 1 1 1 1 PH domain DUF1708 PF08101.11 PRP76700.1 - 0.0059 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) QLQ PF08880.11 PRP76700.1 - 0.029 14.1 3.5 3.1 7.6 0.1 2.7 2 0 0 2 2 2 0 QLQ AKAP28 PF14469.6 PRP76701.1 - 0.22 11.3 1.2 0.95 9.2 1.2 1.8 1 1 0 1 1 1 0 28 kDa A-kinase anchor UbiA PF01040.18 PRP76702.1 - 6.3e-28 97.8 8.2 7.7e-28 97.5 8.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RFC1 PF08519.12 PRP76703.1 - 1.6e-39 135.6 0.2 1.6e-39 135.6 0.2 3.3 4 0 0 4 4 4 1 Replication factor RFC1 C terminal domain AAA PF00004.29 PRP76703.1 - 1.3e-07 32.1 1.3 1.9e-06 28.3 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PRP76703.1 - 0.00021 21.3 0.0 0.00021 21.3 0.0 2.7 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 PRP76703.1 - 0.001 19.4 0.0 0.012 15.9 0.0 3.0 1 0 0 1 1 1 1 AAA C-terminal domain AAA_7 PF12775.7 PRP76703.1 - 0.028 13.9 0.0 0.089 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region RuvB_N PF05496.12 PRP76703.1 - 0.029 14.1 0.0 0.089 12.5 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PRP76703.1 - 0.11 12.9 0.0 0.11 12.9 0.0 4.8 4 2 0 4 4 4 0 AAA ATPase domain DEAD PF00270.29 PRP76703.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 PRP76703.1 - 0.21 11.3 0.0 0.21 11.3 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 PRP76703.1 - 6.5 7.0 9.7 9.8 6.4 0.0 4.2 3 1 0 3 3 3 0 AAA domain Spc7 PF08317.11 PRP76704.1 - 0.0006 18.8 0.2 0.0006 18.8 0.2 2.4 2 1 0 2 2 2 1 Spc7 kinetochore protein IMD PF08397.11 PRP76704.1 - 0.021 14.2 0.4 0.021 14.2 0.4 1.9 2 1 0 2 2 2 0 IRSp53/MIM homology domain DUF4804 PF16062.5 PRP76704.1 - 0.03 13.1 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) HIP1_clath_bdg PF16515.5 PRP76704.1 - 0.048 14.3 0.6 0.048 14.3 0.6 2.4 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HemX PF04375.14 PRP76704.1 - 0.97 8.7 4.9 3.8 6.7 0.7 2.6 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase Herpes_UL3 PF03369.13 PRP76705.1 - 0.19 12.2 0.0 13 6.3 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL3 protein adh_short PF00106.25 PRP76714.1 - 1e-43 149.1 0.0 1.4e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP76714.1 - 3.2e-28 98.9 0.0 4.4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP76714.1 - 3e-08 33.8 0.0 5.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 KR domain CoA_binding_3 PF13727.6 PRP76714.1 - 0.068 13.2 0.1 0.19 11.7 0.1 1.6 2 0 0 2 2 2 0 CoA-binding domain Pkinase_Tyr PF07714.17 PRP76715.1 - 9e-67 225.1 0.1 1e-65 221.6 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76715.1 - 1.8e-48 165.2 0.1 7.3e-48 163.2 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP76715.1 - 2.5e-43 145.6 87.7 9.3e-07 28.5 7.7 14.3 8 3 9 17 17 17 15 Leucine rich repeat LRR_4 PF12799.7 PRP76715.1 - 1.3e-32 111.2 120.4 0.00013 22.3 0.2 18.2 10 5 11 21 21 21 16 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP76715.1 - 4.3e-06 26.5 98.4 3.3 8.6 0.6 24.6 27 1 1 28 28 25 3 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP76715.1 - 1.8e-05 23.8 0.0 4.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP76715.1 - 0.004 16.2 0.4 0.015 14.3 0.4 1.9 1 1 0 1 1 1 1 Haspin like kinase domain LRRNT_2 PF08263.12 PRP76715.1 - 0.0056 17.0 1.0 0.013 15.7 1.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Kinase-like PF14531.6 PRP76715.1 - 0.0064 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP76715.1 - 0.018 14.4 0.0 0.061 12.7 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syndecan PF01034.20 PRP76715.1 - 0.029 14.3 0.5 0.059 13.3 0.5 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 PRP76715.1 - 0.085 13.7 0.1 0.18 12.7 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_6 PF13516.6 PRP76715.1 - 4.3 7.6 78.1 2 8.7 0.1 17.7 20 0 0 20 20 20 0 Leucine Rich repeat GLE1 PF07817.13 PRP76716.1 - 1.4e-48 165.3 0.3 2e-48 164.8 0.3 1.2 1 0 0 1 1 1 1 GLE1-like protein SRP-alpha_N PF04086.13 PRP76716.1 - 0.56 10.1 19.9 0.16 11.9 17.1 1.5 1 1 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Borrelia_P83 PF05262.11 PRP76716.1 - 1 7.8 13.3 1.4 7.4 13.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PriC PF07445.12 PRP76716.1 - 2.2 8.2 13.4 8.9 6.2 7.9 2.4 2 0 0 2 2 2 0 Primosomal replication protein priC Bac_luciferase PF00296.20 PRP76717.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Metallophos PF00149.28 PRP76718.1 - 9.4e-13 49.1 1.1 1.4e-12 48.5 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PRP76718.1 - 5.3e-07 30.0 1.3 1.1e-06 29.0 1.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-CCHC PF00098.23 PRP76720.1 - 0.87 9.8 3.0 0.62 10.2 1.3 1.7 2 0 0 2 2 2 0 Zinc knuckle Rad17 PF03215.15 PRP76722.1 - 6e-22 78.5 0.0 1.2e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 PRP76722.1 - 3.4e-06 27.5 0.0 9.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 PRP76722.1 - 1.1e-05 25.8 0.0 4.6e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP76722.1 - 6.6e-05 23.2 0.0 0.0003 21.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PRP76722.1 - 0.00027 20.7 0.0 0.00059 19.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 PRP76722.1 - 0.0014 19.0 0.0 0.0041 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain T2SSE PF00437.20 PRP76722.1 - 0.0014 17.7 0.1 0.0037 16.4 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 PRP76722.1 - 0.0021 18.6 0.0 0.034 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PRP76722.1 - 0.0047 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 PRP76722.1 - 0.0065 16.8 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 PRP76722.1 - 0.0085 16.3 0.1 0.029 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PRP76722.1 - 0.017 14.7 0.1 0.74 9.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 PRP76722.1 - 0.031 14.1 0.0 0.031 14.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PRP76722.1 - 0.036 13.2 0.0 0.083 12.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 PRP76722.1 - 0.037 13.8 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PRP76722.1 - 0.039 13.9 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 PRP76722.1 - 0.044 13.8 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 PRP76722.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF2075 PF09848.9 PRP76722.1 - 0.063 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 PRP76722.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 PRP76722.1 - 0.076 12.9 0.2 0.31 10.9 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 PRP76722.1 - 0.086 13.4 0.0 0.29 11.6 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin PF02224.18 PRP76722.1 - 0.1 12.3 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA_5 PF07728.14 PRP76722.1 - 0.1 12.6 0.0 0.37 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 PRP76722.1 - 0.13 12.6 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain LRR_8 PF13855.6 PRP76723.1 - 3.8e-23 81.0 45.6 6e-06 25.9 5.5 8.9 6 2 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 PRP76723.1 - 1.6e-15 56.9 61.0 0.01 16.2 2.5 12.2 7 3 8 15 15 15 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP76723.1 - 9.5e-05 22.4 40.2 10 7.1 0.2 13.6 13 1 0 13 13 13 1 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP76723.1 - 0.00029 21.1 1.0 0.00087 19.5 1.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PRP76723.1 - 1.6 9.0 43.6 2.3 8.5 0.4 10.1 11 0 0 11 11 11 0 Leucine Rich repeat ShK PF01549.24 PRP76727.1 - 2.6 8.7 5.3 14 6.3 0.2 2.3 2 0 0 2 2 2 0 ShK domain-like NADH_4Fe-4S PF10589.9 PRP76728.1 - 0.011 15.8 0.4 0.014 15.5 0.4 1.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DEAD PF00270.29 PRP76730.1 - 3.4e-43 147.4 0.1 1.4e-42 145.4 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP76730.1 - 6.5e-32 110.2 0.1 2.6e-31 108.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP76730.1 - 0.00017 21.7 0.0 0.00054 20.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 PRP76730.1 - 0.00027 20.9 2.0 0.00045 20.2 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle AAA_22 PF13401.6 PRP76730.1 - 0.02 15.2 2.4 0.3 11.3 0.1 3.6 4 0 0 4 4 4 0 AAA domain zf-CCHC_4 PF14392.6 PRP76730.1 - 0.18 11.6 0.8 0.47 10.2 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle ANTH PF07651.16 PRP76731.1 - 1.1e-42 146.0 0.0 1.1e-42 146.0 0.0 2.7 3 0 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 PRP76731.1 - 1.1e-40 139.4 10.1 1.1e-40 139.4 10.1 7.3 3 2 4 8 8 8 2 I/LWEQ domain GFO_IDH_MocA_C PF02894.17 PRP76732.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 PRP76732.1 - 0.21 12.4 0.0 0.38 11.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_M48 PF01435.18 PRP76733.1 - 7.8e-31 107.4 0.6 1.5e-30 106.5 0.6 1.4 1 0 0 1 1 1 1 Peptidase family M48 NopRA1 PF16201.5 PRP76733.1 - 0.056 13.0 0.8 0.11 12.1 0.2 1.9 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 ATP-grasp_4 PF13535.6 PRP76733.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain FoP_duplication PF13865.6 PRP76734.1 - 3.5e-12 46.7 23.5 2e-11 44.3 23.5 2.1 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 GRP PF07172.11 PRP76734.1 - 0.59 10.8 23.6 1.1 10.0 23.6 1.4 1 0 0 1 1 1 0 Glycine rich protein family Pro_isomerase PF00160.21 PRP76735.1 - 1e-49 168.9 0.5 1.9e-49 168.0 0.5 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 PRP76735.1 - 5.1e-09 36.6 0.2 0.031 15.1 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76735.1 - 0.0005 20.3 0.0 10 6.5 0.0 4.9 3 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 PRP76735.1 - 0.021 13.3 0.2 0.037 12.6 0.2 1.4 1 1 0 1 1 1 0 Utp8 family Nucleoporin_N PF08801.11 PRP76735.1 - 0.1 11.3 0.0 2.1 7.0 0.1 2.3 1 1 1 2 2 2 0 Nup133 N terminal like zf-RING_4 PF14570.6 PRP76736.1 - 2.4e-09 36.8 5.9 8.4e-09 35.1 5.9 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 PRP76736.1 - 3e-05 23.7 0.0 9.6e-05 22.1 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PP2C_2 PF13672.6 PRP76736.1 - 0.00013 21.6 0.0 0.00082 19.1 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C Rubredoxin_2 PF18073.1 PRP76736.1 - 0.05 13.3 5.3 0.12 12.1 5.3 1.7 1 0 0 1 1 1 0 Rubredoxin metal binding domain zf-C3HC4_3 PF13920.6 PRP76736.1 - 0.17 11.8 4.0 0.34 10.8 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 PRP76736.1 - 0.21 12.1 1.7 0.5 10.9 1.7 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PRP76736.1 - 0.34 11.6 0.1 0.34 11.6 0.1 3.8 3 0 0 3 3 3 0 Torus domain zf-RING_2 PF13639.6 PRP76736.1 - 4.5 7.7 5.7 11 6.4 5.7 1.7 1 0 0 1 1 1 0 Ring finger domain DEAD PF00270.29 PRP76737.1 - 3.5e-39 134.4 0.1 6.6e-39 133.5 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP76737.1 - 2.8e-29 101.7 0.3 2.2e-27 95.6 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 PRP76737.1 - 0.00098 18.9 0.1 0.023 14.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP76737.1 - 0.025 14.9 0.1 0.076 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain BUD22 PF09073.10 PRP76737.1 - 0.057 12.8 13.6 0.087 12.1 13.6 1.2 1 0 0 1 1 1 0 BUD22 UTP25 PF06862.12 PRP76737.1 - 0.086 11.6 6.7 0.61 8.8 0.0 3.0 3 1 1 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 RNA_pol_3_Rpc31 PF11705.8 PRP76737.1 - 0.34 11.1 17.3 0.66 10.2 17.3 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM60A PF15396.6 PRP76737.1 - 1.2 9.1 6.1 2 8.4 6.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 PRP76737.1 - 1.6 7.4 5.7 2.9 6.6 5.7 1.3 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 PRP76737.1 - 1.8 8.0 10.8 3.1 7.2 10.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DNA_pol_phi PF04931.13 PRP76737.1 - 1.9 6.5 15.0 2.9 5.9 15.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi CoaE PF01121.20 PRP76738.1 - 2.6e-55 186.9 0.1 3.1e-55 186.6 0.1 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 PRP76738.1 - 0.00083 19.5 0.0 0.65 10.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 PRP76738.1 - 0.0022 18.5 0.3 0.0063 17.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain Pkinase PF00069.25 PRP76739.1 - 1.1e-17 64.3 0.0 2.2e-16 60.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76739.1 - 2e-14 53.5 0.0 6.3e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 PRP76739.1 - 9e-05 22.4 0.0 12 6.5 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 PRP76739.1 - 0.0043 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF4569 PF15133.6 PRP76739.1 - 0.44 10.2 4.1 0.57 9.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4569) PH_4 PF15404.6 PRP76739.1 - 1.3 8.8 5.2 21 4.8 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PRK PF00485.18 PRP76740.1 - 1.1e-52 178.7 0.3 1.4e-52 178.3 0.3 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 PRP76740.1 - 8.4e-05 23.1 0.0 0.00019 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP76740.1 - 9e-05 21.8 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 PRP76740.1 - 0.0035 17.8 0.3 2.8 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain Cytidylate_kin PF02224.18 PRP76740.1 - 0.0035 17.1 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 2 Cytidylate kinase T2SSE PF00437.20 PRP76740.1 - 0.0041 16.2 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein CoaE PF01121.20 PRP76740.1 - 0.0043 16.8 0.2 0.14 11.8 0.0 2.1 2 0 0 2 2 2 1 Dephospho-CoA kinase MORN PF02493.20 PRP76741.1 - 1.1e-40 135.2 58.4 8.8e-07 28.5 5.0 13.1 13 0 0 13 13 13 12 MORN repeat DHHA1 PF02272.19 PRP76741.1 - 0.022 15.2 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 DHHA1 domain Yos1 PF08571.10 PRP76742.1 - 2e-21 76.0 1.0 2.5e-21 75.7 1.0 1.1 1 0 0 1 1 1 1 Yos1-like 2OG-FeII_Oxy_2 PF13532.6 PRP76743.1 - 6.4e-22 78.7 0.1 7.9e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MT-A70 PF05063.14 PRP76744.1 - 2.1e-38 131.9 0.0 2.8e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 MT-A70 LepB_GAP_N PF18172.1 PRP76745.1 - 0.035 14.0 0.2 0.076 12.9 0.2 1.5 1 0 0 1 1 1 0 LepB GAP domain N-terminal subdomain DUF3599 PF12206.8 PRP76745.1 - 0.059 13.7 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) HATPase_c PF02518.26 PRP76746.1 - 1.9e-28 99.2 0.1 4.8e-28 97.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP76746.1 - 3.4e-25 88.4 1.8 1.2e-22 80.2 0.4 3.4 2 0 0 2 2 2 1 Response regulator receiver domain Ank_2 PF12796.7 PRP76746.1 - 4.6e-18 65.6 1.8 5.1e-11 43.0 0.3 2.2 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) HisKA PF00512.25 PRP76746.1 - 7.9e-14 51.5 0.0 3e-13 49.6 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Ank_4 PF13637.6 PRP76746.1 - 6.6e-13 48.9 0.2 2.1e-10 40.9 0.1 2.8 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP76746.1 - 1.9e-09 37.6 0.4 1e-07 32.1 0.1 3.1 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP76746.1 - 2.8e-07 30.7 1.1 0.00034 20.9 0.2 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP76746.1 - 1.3e-06 28.2 0.1 0.0063 16.9 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeat HATPase_c_5 PF14501.6 PRP76746.1 - 0.0017 18.2 0.0 0.0071 16.2 0.0 2.1 1 0 0 1 1 1 1 GHKL domain PAS_9 PF13426.7 PRP76746.1 - 0.0054 17.0 0.1 0.78 10.0 0.0 3.4 2 0 0 2 2 2 1 PAS domain MEKHLA PF08670.11 PRP76746.1 - 0.021 14.7 0.0 0.063 13.2 0.0 1.8 1 0 0 1 1 1 0 MEKHLA domain Zn_clus PF00172.18 PRP76747.1 - 0.059 13.5 11.7 0.2 11.8 11.7 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NT5C PF06941.12 PRP76747.1 - 0.076 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) MAM33 PF02330.16 PRP76747.1 - 0.092 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein Glyco_hydro_18 PF00704.28 PRP76748.1 - 3.8e-17 63.0 0.9 8.6e-17 61.8 0.9 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP76748.1 - 3e-05 24.4 22.3 5.6e-05 23.5 22.3 1.4 1 0 0 1 1 1 1 Chitin recognition protein EMP70 PF02990.16 PRP76749.1 - 9e-137 456.9 12.8 9e-137 456.9 12.8 1.7 1 1 1 2 2 2 1 Endomembrane protein 70 DUF5305 PF17231.2 PRP76749.1 - 7.7 5.8 7.1 7.6 5.9 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Wzz PF02706.15 PRP76749.1 - 7.9 6.9 0.0 7.9 6.9 0.0 3.6 4 0 0 4 4 4 0 Chain length determinant protein DUF1748 PF08520.10 PRP76750.1 - 9.8e-12 44.6 0.0 1.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) SAPS PF04499.15 PRP76752.1 - 0.48 9.2 11.5 0.67 8.7 11.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 PRP76752.1 - 0.49 8.5 13.0 0.64 8.2 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family HSD3 PF15244.6 PRP76752.1 - 0.91 9.0 8.9 0.38 10.2 6.4 1.6 2 0 0 2 2 2 0 Spermatogenesis-associated protein 7, or HSD3 PNISR PF15996.5 PRP76752.1 - 2.3 8.5 17.4 3.4 7.9 17.4 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR BUD22 PF09073.10 PRP76752.1 - 4.2 6.6 18.3 5.8 6.1 18.3 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 PRP76752.1 - 7.9 4.4 11.1 10 4.1 11.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 PRP76753.1 - 3.9e-70 236.2 0.0 4.9e-70 235.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76753.1 - 1.2e-43 149.3 0.0 1.8e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP76753.1 - 8.1e-08 31.9 0.0 9.4e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP76753.1 - 1.3e-06 28.0 0.4 2.1e-06 27.2 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP76753.1 - 4.6e-05 23.5 0.0 0.0018 18.3 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP76753.1 - 0.00026 20.6 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 PRP76753.1 - 0.0011 17.8 0.5 0.002 17.0 0.5 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP76753.1 - 0.0077 15.2 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 PRP76753.1 - 0.14 11.7 0.2 0.4 10.2 0.2 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 PRP76753.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 ANAPC4_WD40 PF12894.7 PRP76754.1 - 4.1e-06 27.0 0.4 0.012 15.8 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP76754.1 - 1.2e-05 26.0 16.1 0.05 14.5 0.6 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.7 PRP76754.1 - 0.00042 20.1 5.0 0.0013 18.5 0.5 3.3 3 1 0 3 3 3 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 PRP76754.1 - 0.0032 17.2 0.0 0.0032 17.2 0.0 2.2 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Rotamase_2 PF13145.6 PRP76754.1 - 0.089 13.6 3.9 2.3 9.1 0.1 2.8 2 0 0 2 2 2 0 PPIC-type PPIASE domain Helicase_C_2 PF13307.6 PRP76754.1 - 0.099 12.8 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain VPS13 PF16908.5 PRP76755.1 - 1.7e-61 208.1 1.9 1.7e-61 208.1 1.9 2.7 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 PRP76755.1 - 7.4e-30 104.1 0.1 7.4e-30 104.1 0.1 2.0 3 0 0 3 3 3 1 Repeating coiled region of VPS13 Chorein_N PF12624.7 PRP76755.1 - 9.9e-29 99.8 0.3 3.6e-28 98.0 0.3 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 MutL PF13941.6 PRP76755.1 - 0.22 10.1 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 MutL protein Amino_oxidase PF01593.24 PRP76756.1 - 1.7e-89 301.2 0.0 1.4e-88 298.2 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP76756.1 - 4.4e-11 42.8 0.2 9.7e-11 41.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP76756.1 - 7.4e-07 29.1 1.6 9e-06 25.5 0.4 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PRP76756.1 - 1.8e-05 24.1 1.1 3.3e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP76756.1 - 6.3e-05 22.3 0.2 0.00023 20.5 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PRP76756.1 - 9.9e-05 21.9 1.6 0.0002 20.9 0.7 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PRP76756.1 - 0.00015 21.1 0.1 0.00027 20.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PRP76756.1 - 0.00016 21.0 0.1 0.00029 20.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family SWIRM PF04433.17 PRP76756.1 - 0.00027 21.2 1.1 0.0012 19.1 0.1 2.3 2 0 0 2 2 2 1 SWIRM domain HI0933_like PF03486.14 PRP76756.1 - 0.0013 17.5 1.4 0.0031 16.3 1.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 PRP76756.1 - 0.0017 18.9 0.1 0.0096 16.5 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PRP76756.1 - 0.005 16.0 1.4 0.0061 15.7 0.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PRP76756.1 - 0.0064 15.6 0.1 0.0099 15.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 PRP76756.1 - 0.0075 15.6 1.5 0.016 14.5 0.6 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PRP76756.1 - 0.052 12.8 1.8 0.11 11.7 1.8 1.4 1 0 0 1 1 1 0 FAD binding domain Fascin PF06268.13 PRP76757.1 - 2.4e-16 59.9 1.1 0.00013 22.1 0.0 4.4 2 1 2 4 4 4 4 Fascin domain FGF PF00167.18 PRP76757.1 - 4.1e-06 26.9 0.0 0.73 10.0 0.0 4.7 2 1 2 5 5 5 1 Fibroblast growth factor RicinB_lectin_2 PF14200.6 PRP76757.1 - 0.00012 22.7 0.5 0.36 11.6 0.0 4.3 2 1 4 6 6 6 2 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 PRP76757.1 - 0.00045 20.0 0.1 0.048 13.4 0.0 3.4 2 2 2 4 4 4 1 FRG1-like domain MIR PF02815.19 PRP76757.1 - 0.11 12.3 0.1 1.7 8.5 0.1 2.6 2 1 1 3 3 3 0 MIR domain CPP1-like PF11833.8 PRP76760.1 - 0.28 10.8 2.0 0.4 10.3 2.0 1.3 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Herpes_LMP1 PF05297.11 PRP76760.1 - 0.63 9.2 5.7 0.64 9.2 5.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VIT1 PF01988.19 PRP76760.1 - 1 9.2 2.9 1.5 8.6 2.9 1.2 1 0 0 1 1 1 0 VIT family Tetraspanin PF00335.20 PRP76760.1 - 4.4 7.0 15.6 5.3 6.7 15.6 1.3 1 1 0 1 1 1 0 Tetraspanin family Anoctamin PF04547.12 PRP76761.1 - 2.5e-107 359.5 19.9 3.4e-107 359.1 19.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PRP76761.1 - 9.3e-11 41.9 0.6 2.1e-10 40.8 0.6 1.6 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DUF21 PF01595.20 PRP76761.1 - 0.25 11.1 8.4 0.11 12.2 0.1 2.7 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain ubiquitin PF00240.23 PRP76762.1 - 1.8e-06 27.6 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP76762.1 - 0.0003 20.6 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like OPT PF03169.15 PRP76763.1 - 8e-136 454.2 23.3 1.2e-135 453.6 23.3 1.3 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RhoGEF PF00621.20 PRP76763.1 - 8.8e-42 143.4 1.7 2e-41 142.2 1.7 1.7 1 0 0 1 1 1 1 RhoGEF domain Ras PF00071.22 PRP76763.1 - 2.8e-06 27.0 0.2 6.8e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Ras family PH PF00169.29 PRP76763.1 - 1.2e-05 25.7 0.0 5.8e-05 23.5 0.0 2.2 1 0 0 1 1 1 1 PH domain SRPRB PF09439.10 PRP76763.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF3995 PF13160.6 PRP76763.1 - 0.37 11.2 8.0 0.093 13.1 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) bMG10 PF17973.1 PRP76764.1 - 1.6e-31 109.2 0.1 4.6e-31 107.7 0.1 1.9 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M PF00207.22 PRP76764.1 - 5.3e-18 64.7 0.5 3.7e-17 62.0 0.0 2.8 3 0 0 3 3 3 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 PRP76764.1 - 3e-17 63.3 0.7 3.3e-16 59.9 0.7 3.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 PRP76764.1 - 1.2e-16 60.9 0.7 2.9e-15 56.5 0.0 3.6 5 0 0 5 5 4 1 MG2 domain Big_5 PF13205.6 PRP76764.1 - 5.1e-06 27.1 5.9 0.22 12.2 0.2 6.0 5 1 1 6 6 6 1 Bacterial Ig-like domain DUF11 PF01345.18 PRP76764.1 - 1.7e-05 25.0 0.1 0.0053 17.0 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function DUF11 bMG5 PF17972.1 PRP76764.1 - 2.4e-05 24.7 0.0 0.00046 20.5 0.0 3.1 3 0 0 3 3 2 1 Bacterial Alpha-2-macroglobulin MG5 domain TED_complement PF07678.14 PRP76764.1 - 0.0033 16.5 0.0 0.083 11.9 0.0 2.1 2 0 0 2 2 2 1 A-macroglobulin TED domain Big_9 PF17963.1 PRP76764.1 - 0.11 13.2 1.6 11 6.8 0.1 4.3 4 0 0 4 4 4 0 Bacterial Ig domain Big_1 PF02369.16 PRP76764.1 - 0.18 11.9 11.9 8.1 6.5 0.1 6.5 7 1 0 7 7 7 0 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 PRP76764.1 - 0.52 10.6 7.8 25 5.2 0.1 5.9 5 0 0 5 5 5 0 Carboxypeptidase regulatory-like domain Invasin_D3 PF09134.10 PRP76764.1 - 1.3 9.4 11.2 6.7 7.1 0.3 3.7 4 0 0 4 4 4 0 Invasin, domain 3 tRNA-synt_2_TM PF16995.5 PRP76769.1 - 0.0053 16.5 0.1 0.0077 15.9 0.1 1.2 1 0 0 1 1 1 1 Transmembrane region of lysyl-tRNA synthetase Styelin PF17562.2 PRP76771.1 - 0.029 14.7 0.0 0.071 13.5 0.0 1.6 1 0 0 1 1 1 0 Styelin HNH_2 PF13391.6 PRP76771.1 - 0.056 13.6 0.0 0.18 12.0 0.0 1.9 1 1 0 1 1 1 0 HNH endonuclease COesterase PF00135.28 PRP76775.1 - 1.5e-82 278.1 0.6 2.1e-82 277.6 0.6 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP76775.1 - 7.3e-05 22.7 1.9 0.0017 18.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold NUDIX PF00293.28 PRP76777.1 - 1.1e-05 25.4 0.1 1.8e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Helicase_C PF00271.31 PRP76779.1 - 2e-07 31.3 0.6 4e-07 30.4 0.6 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Asp-B-Hydro_N PF05279.11 PRP76779.1 - 0.0047 17.0 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region FAM60A PF15396.6 PRP76779.1 - 0.048 13.7 3.5 0.074 13.0 3.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SWIRM-assoc_2 PF16496.5 PRP76779.1 - 3.9 6.3 12.3 6.8 5.4 9.1 2.5 2 1 1 3 3 3 0 SWIRM-associated domain at the N-terminal GCV_H PF01597.19 PRP76780.1 - 1.1e-39 135.1 0.1 1.3e-39 134.9 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 PRP76780.1 - 0.0036 17.1 0.1 0.0059 16.4 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Aldo_ket_red PF00248.21 PRP76781.1 - 3.3e-42 144.7 0.0 2.1e-41 142.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family zf-C2H2_2 PF12756.7 PRP76782.1 - 1.2e-31 109.0 17.1 9.3e-27 93.3 4.2 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PRP76782.1 - 1.9e-08 34.4 22.7 9.4e-06 25.8 4.3 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP76782.1 - 2.8e-06 27.5 2.9 2.8e-06 27.5 2.9 3.3 4 0 0 4 4 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 PRP76782.1 - 0.00037 20.8 20.9 0.0012 19.2 0.7 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP76782.1 - 0.0076 17.0 16.5 0.3 12.0 0.1 5.2 5 0 0 5 5 5 1 C2H2-type zinc finger AKAP95 PF04988.12 PRP76782.1 - 0.011 16.0 4.9 1.8 8.8 0.1 3.2 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.12 PRP76782.1 - 0.012 15.7 1.4 0.012 15.7 1.4 3.7 3 0 0 3 3 3 0 DBF zinc finger Mut7-C PF01927.16 PRP76782.1 - 0.93 9.6 7.6 1 9.5 2.0 3.0 1 1 1 3 3 3 0 Mut7-C RNAse domain zf-BED PF02892.15 PRP76782.1 - 2.5 8.2 6.5 6 7.0 0.6 3.6 3 0 0 3 3 3 0 BED zinc finger BIR PF00653.21 PRP76782.1 - 2.8 8.7 9.7 15 6.3 0.7 3.7 4 0 0 4 4 4 0 Inhibitor of Apoptosis domain zf-3CxxC PF13695.6 PRP76782.1 - 5 7.7 9.3 0.51 10.8 3.7 2.2 3 0 0 3 3 2 0 Zinc-binding domain zinc_ribbon_4 PF13717.6 PRP76782.1 - 5.3 7.1 6.8 48 4.0 0.9 3.3 3 0 0 3 3 3 0 zinc-ribbon domain CxC1 PF18802.1 PRP76783.1 - 0.049 13.8 0.1 0.049 13.8 0.1 1.1 1 0 0 1 1 1 0 CxC1 like cysteine cluster associated with KDZ transposases PseudoU_synth_2 PF00849.22 PRP76784.1 - 6.9e-20 71.7 0.5 9.8e-20 71.2 0.5 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2090 PF09863.9 PRP76784.1 - 0.042 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Herpes_Helicase PF02689.14 PRP76785.1 - 0.0027 15.7 0.0 0.0039 15.2 0.0 1.2 1 1 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 PRP76785.1 - 0.0034 17.2 0.5 0.01 15.6 0.1 2.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PRP76785.1 - 0.07 12.9 0.2 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Exo_endo_phos PF03372.23 PRP76787.1 - 1.6e-09 37.6 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF393 PF04134.12 PRP76788.1 - 1.1e-24 87.9 0.0 1.4e-24 87.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 tRNA-synt_1c PF00749.21 PRP76789.1 - 2.1e-100 335.7 0.0 4.1e-100 334.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain SGS PF05002.15 PRP76790.1 - 4.3e-29 100.4 1.2 1.4e-28 98.8 1.2 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.16 PRP76790.1 - 2.2e-11 44.6 0.1 3.8e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 CS domain TPR_19 PF14559.6 PRP76790.1 - 0.00026 21.4 0.0 0.00048 20.6 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP76790.1 - 0.00069 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP76790.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP76790.1 - 0.02 15.5 0.0 0.032 14.9 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP76790.1 - 0.047 13.8 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Motilin_assoc PF04643.12 PRP76790.1 - 0.12 12.2 0.1 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 Motilin/ghrelin-associated peptide Alkyl_sulf_dimr PF14863.6 PRP76790.1 - 0.12 12.8 0.1 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Rap_GAP PF02145.15 PRP76791.1 - 1.4e-59 200.8 0.0 3.9e-59 199.3 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP TMF_TATA_bd PF12325.8 PRP76791.1 - 0.029 14.6 0.1 0.029 14.6 0.1 4.8 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.11 PRP76791.1 - 0.091 12.8 3.5 2.8 8.0 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) PT-VENN PF04829.13 PRP76791.1 - 0.16 12.0 0.9 0.35 11.0 0.1 2.0 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif DUF1664 PF07889.12 PRP76791.1 - 0.98 9.5 24.0 2.1 8.4 0.9 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) SlyX PF04102.12 PRP76791.1 - 1 10.0 0.0 1 10.0 0.0 4.9 4 1 1 5 5 5 0 SlyX Seryl_tRNA_N PF02403.22 PRP76791.1 - 2.7 8.3 22.1 0.04 14.2 2.5 3.8 1 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 PRP76791.1 - 4.2 7.9 27.1 5.5 7.5 0.3 6.2 6 1 1 7 7 7 0 Flagella accessory protein C (FlaC) PKcGMP_CC PF16808.5 PRP76791.1 - 4.2 7.3 9.4 12 5.9 0.2 4.9 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PPR PF01535.20 PRP76792.1 - 0.00011 22.3 0.1 2.2 8.7 0.0 4.3 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 PRP76792.1 - 0.00025 21.0 0.7 0.42 10.7 0.0 2.8 3 0 0 3 3 3 2 Pentatricopeptide repeat domain ATP13 PF12921.7 PRP76792.1 - 0.0023 17.8 0.0 0.022 14.6 0.0 2.4 1 1 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.6 PRP76792.1 - 0.0029 17.8 0.1 23 5.3 0.0 3.8 3 1 1 4 4 4 1 PPR repeat family DUF496 PF04363.12 PRP76792.1 - 0.059 13.4 1.9 0.13 12.3 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Metallophos PF00149.28 PRP76793.1 - 2e-14 54.6 2.8 5.5e-14 53.1 2.8 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PRP76793.1 - 3e-09 37.6 0.1 6.5e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 PRP76793.1 - 0.0012 19.4 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 PRP76793.1 - 0.0085 16.3 0.0 0.047 13.9 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 PRP76793.1 - 0.02 13.9 0.2 2.9 6.8 0.1 2.8 2 1 0 2 2 2 0 PhoD-like phosphatase DUF481 PF04338.12 PRP76793.1 - 0.092 12.7 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF481 Cupin_8 PF13621.6 PRP76796.1 - 5.1e-16 59.1 3.3 1.7e-11 44.4 1.2 3.1 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 PRP76796.1 - 1.7e-05 24.5 0.1 2.5e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PRP76796.1 - 0.025 15.0 0.0 0.2 12.1 0.0 2.5 2 0 0 2 2 2 0 JmjC domain, hydroxylase CTP_synth_N PF06418.14 PRP76797.1 - 9.8e-125 415.2 0.1 1.6e-124 414.5 0.1 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 PRP76797.1 - 5.4e-52 176.3 0.0 9.8e-52 175.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PRP76797.1 - 7.7e-07 29.1 0.0 2.1e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 PRP76797.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TBPIP_N PF15517.6 PRP76797.1 - 0.11 12.6 0.1 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 TBP-interacting protein N-terminus ATP-synt_8 PF00895.20 PRP76800.1 - 0.0054 17.2 3.4 0.01 16.3 3.4 1.4 1 0 0 1 1 1 1 ATP synthase protein 8 LMBR1 PF04791.16 PRP76800.1 - 0.012 14.5 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LRR_4 PF12799.7 PRP76802.1 - 2.5e-18 65.9 6.9 2.9e-08 33.9 0.1 5.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP76802.1 - 1.8e-17 63.4 0.1 7.5e-13 48.3 0.0 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 PRP76802.1 - 1.2e-11 44.2 2.7 1.6e-06 27.8 0.2 3.2 2 1 0 2 2 2 2 Leucine rich repeat Lung_7-TM_R PF06814.13 PRP76802.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Lung seven transmembrane receptor Exonuc_VII_L PF02601.15 PRP76802.1 - 2.5 7.6 8.8 4.6 6.7 8.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit RICH PF05062.12 PRP76802.1 - 5 7.5 10.8 0.42 11.0 2.0 3.1 3 0 0 3 3 3 0 RICH domain FapA PF03961.13 PRP76802.1 - 9.4 4.7 8.9 16 3.9 8.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TLD PF07534.16 PRP76803.1 - 9.9e-19 67.9 0.0 1.7e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 PRP76803.1 - 0.013 15.1 0.8 0.066 12.9 0.8 2.1 1 1 0 1 1 1 0 Rab-GTPase-TBC domain HTH_39 PF14090.6 PRP76803.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_22 PF13401.6 PRP76804.1 - 0.0036 17.6 0.0 0.015 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PRP76804.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SNURF PF07192.11 PRP76805.1 - 0.12 12.3 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 SNURF/RPN4 protein DUF4034 PF13226.6 PRP76806.1 - 0.0036 16.7 0.0 0.0069 15.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4034) Sigma70_ECF PF07638.11 PRP76807.1 - 0.16 11.8 0.5 0.23 11.3 0.5 1.2 1 0 0 1 1 1 0 ECF sigma factor ACCA PF03255.14 PRP76810.1 - 0.37 10.7 2.6 0.38 10.6 0.6 1.8 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ank_4 PF13637.6 PRP76811.1 - 0.00045 20.7 0.0 6.7 7.4 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76811.1 - 0.037 14.6 0.0 24 5.9 0.0 5.1 8 0 0 8 8 8 0 Ankyrin repeat Ceramidase PF05875.12 PRP76812.1 - 1.6e-60 204.8 14.0 1.8e-60 204.6 14.0 1.0 1 0 0 1 1 1 1 Ceramidase ECF_trnsprt PF12822.7 PRP76812.1 - 0.0087 16.2 3.6 0.0087 16.2 3.6 2.3 1 1 1 2 2 2 1 ECF transporter, substrate-specific component DUF3377 PF11857.8 PRP76812.1 - 0.064 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) YrhK PF14145.6 PRP76812.1 - 1.3 8.9 7.4 24 4.9 4.7 3.3 2 1 0 2 2 2 0 YrhK-like protein CTP_transf_1 PF01148.20 PRP76812.1 - 5.1 6.8 11.1 11 5.7 11.1 1.7 1 1 0 1 1 1 0 Cytidylyltransferase family CDC45 PF02724.14 PRP76814.1 - 0.03 12.7 0.4 0.027 12.8 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 PRP76814.1 - 0.077 12.8 4.4 0.11 12.2 4.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 PRP76814.1 - 4.8 6.8 7.7 5.7 6.6 7.3 1.4 1 1 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 PRP76814.1 - 4.8 7.6 9.2 7.7 7.0 9.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Torsin PF06309.11 PRP76815.1 - 3.8e-10 39.9 0.0 8.9e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.6 PRP76815.1 - 8.9e-06 26.0 0.5 0.00064 20.0 0.5 2.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 PRP76815.1 - 0.0026 18.2 0.1 0.0056 17.1 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP76815.1 - 0.008 16.6 0.1 1.1 9.7 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 PRP76815.1 - 0.0096 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF87 PF01935.17 PRP76815.1 - 0.018 15.2 0.2 0.054 13.6 0.2 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 PRP76815.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CAF1 PF04857.20 PRP76817.1 - 2.9e-73 246.8 0.0 3.4e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 PRP76817.1 - 3e-05 23.9 0.1 6.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 RNA binding domain GAD-like PF08887.11 PRP76817.1 - 0.014 15.2 0.1 1.2 9.0 0.0 3.3 3 1 1 4 4 4 0 GAD-like domain NCBP3 PF10309.9 PRP76817.1 - 0.026 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 DNA_pol_A_exo1 PF01612.20 PRP76817.1 - 0.033 13.9 0.0 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 3'-5' exonuclease TPR_2 PF07719.17 PRP76818.1 - 0.014 15.4 0.0 10 6.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4080 PF13311.6 PRP76818.1 - 0.016 15.4 0.6 0.56 10.4 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Uds1 PF15456.6 PRP76818.1 - 0.049 13.8 0.3 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Up-regulated During Septation F-box PF00646.33 PRP76819.1 - 3.7e-06 26.7 1.0 8.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP76819.1 - 0.00027 20.8 0.1 0.00085 19.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 PRP76819.1 - 0.026 14.4 0.6 0.026 14.4 0.6 2.3 2 1 1 3 3 3 0 F-box Cas6_N PF17952.1 PRP76819.1 - 0.23 11.8 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 Cas6 N-terminal domain Ank_4 PF13637.6 PRP76820.1 - 0.13 12.9 0.1 0.25 12.0 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) BAR PF03114.18 PRP76823.1 - 7.7e-19 68.3 7.2 1.3e-18 67.6 7.2 1.3 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 PRP76823.1 - 0.27 10.7 8.0 1.8 8.1 8.0 2.0 1 1 0 1 1 1 0 Arfaptin-like domain Peroxidase_2 PF01328.17 PRP76824.1 - 7e-37 127.8 0.0 1.1e-36 127.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 PRRSV_Env PF02340.15 PRP76824.1 - 0.36 10.2 3.7 0.41 10.0 2.5 1.6 2 0 0 2 2 2 0 PRRSV putative envelope protein CDP-OH_P_transf PF01066.21 PRP76827.1 - 1.9e-12 47.7 1.2 1.9e-12 47.7 1.2 3.4 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Spore_YhaL PF14147.6 PRP76827.1 - 0.46 10.2 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein YhaL Guanylate_cyc PF00211.20 PRP76828.1 - 2.4e-52 177.2 0.0 1.8e-29 102.6 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Mito_carr PF00153.27 PRP76828.1 - 1.2e-12 47.6 0.0 2.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial carrier protein Phage_T4_gp36 PF03903.13 PRP76830.1 - 0.0041 17.1 0.6 0.016 15.2 0.6 2.0 1 0 0 1 1 1 1 Phage T4 tail fibre Ank_2 PF12796.7 PRP76831.1 - 2.4e-18 66.5 0.1 8.8e-11 42.3 0.1 3.6 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76831.1 - 1.7e-13 50.8 0.1 2.8e-05 24.6 0.0 5.6 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP76831.1 - 1.9e-13 50.3 2.7 7.9e-06 26.0 0.1 5.2 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76831.1 - 7.9e-12 44.3 6.7 3.1e-05 24.0 0.0 6.5 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 PRP76831.1 - 3.4e-11 43.1 1.4 1.2e-07 31.8 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat F-box-like PF12937.7 PRP76831.1 - 2.5e-05 24.1 3.0 5.9e-05 22.9 3.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP76831.1 - 0.00041 20.1 1.1 0.0011 18.8 1.1 1.8 1 0 0 1 1 1 1 F-box domain Mito_carr PF00153.27 PRP76833.1 - 6.5e-66 218.3 0.2 3.4e-22 78.2 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Guanylate_cyc PF00211.20 PRP76833.1 - 1e-51 175.2 0.0 3.2e-29 101.8 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Glyco_hydro_cc PF11790.8 PRP76834.1 - 2.5e-61 207.3 4.4 3.8e-61 206.7 4.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fascin PF06268.13 PRP76834.1 - 1.7e-06 28.2 0.1 1.2e-05 25.4 0.1 2.1 1 1 0 1 1 1 1 Fascin domain FRG1 PF06229.12 PRP76834.1 - 0.018 14.8 0.1 2.3 7.9 0.0 2.2 1 1 1 2 2 2 0 FRG1-like domain RicinB_lectin_2 PF14200.6 PRP76834.1 - 0.029 15.1 0.4 0.029 15.1 0.4 2.3 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin domain-like MukB PF04310.12 PRP76835.1 - 0.0013 18.6 0.5 0.0021 17.9 0.5 1.4 1 0 0 1 1 1 1 MukB N-terminal UPF0158 PF03682.13 PRP76835.1 - 0.0045 17.0 1.4 0.0092 16.0 1.4 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0158) Diphtheria_T PF02764.14 PRP76835.1 - 0.042 13.9 0.2 0.062 13.3 0.2 1.3 1 0 0 1 1 1 0 Diphtheria toxin, T domain Torus PF16131.5 PRP76835.1 - 0.054 14.2 0.6 0.054 14.2 0.6 3.7 2 2 2 4 4 4 0 Torus domain DnaJ PF00226.31 PRP76836.1 - 0.0014 18.7 3.4 0.0038 17.3 0.1 2.9 2 1 1 3 3 3 1 DnaJ domain SR-25 PF10500.9 PRP76836.1 - 0.0029 17.3 5.9 0.0043 16.7 5.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4140 PF13600.6 PRP76836.1 - 0.61 10.6 2.6 1 9.8 2.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Hid1 PF12722.7 PRP76836.1 - 1.6 6.7 2.9 2 6.4 2.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 PRP76836.1 - 4.1 5.6 6.4 4.8 5.4 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein OmpH PF03938.14 PRP76836.1 - 7.5 6.9 9.4 14 6.0 9.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rcd1 PF04078.13 PRP76837.1 - 5.5e-127 422.4 1.0 6.3e-127 422.2 1.0 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Ndr PF03096.14 PRP76838.1 - 2.4e-48 164.3 0.0 4.1e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family Fascin PF06268.13 PRP76840.1 - 1e-10 41.8 0.1 3e-10 40.3 0.1 1.7 1 1 0 1 1 1 1 Fascin domain FRG1 PF06229.12 PRP76840.1 - 7.2e-07 29.1 0.2 0.039 13.7 0.1 2.3 1 1 1 2 2 2 2 FRG1-like domain FGF PF00167.18 PRP76840.1 - 4e-05 23.7 0.9 0.023 14.8 0.1 2.1 1 1 1 2 2 2 2 Fibroblast growth factor Ank_3 PF13606.6 PRP76841.1 - 1.1e-13 50.0 0.1 0.0007 19.9 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 PRP76841.1 - 2.8e-13 50.3 0.1 6.2e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) BTB PF00651.31 PRP76841.1 - 2.7e-12 46.9 0.4 6.9e-12 45.6 0.4 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.6 PRP76841.1 - 1e-10 41.9 0.5 0.00017 22.1 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP76841.1 - 7.1e-10 38.9 1.9 0.021 15.2 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PRP76841.1 - 7.8e-07 29.3 0.0 0.061 13.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF1996 PF09362.10 PRP76842.1 - 5.1e-72 242.7 1.2 8.7e-72 241.9 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RicinB_lectin_2 PF14200.6 PRP76842.1 - 1.5 9.6 10.2 0.37 11.5 3.4 3.1 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Phage_TAC_7 PF10109.9 PRP76843.1 - 0.053 13.6 0.0 16 5.7 0.0 3.5 2 1 1 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 SNF2_N PF00176.23 PRP76844.1 - 3.8e-33 114.7 0.1 6.8e-33 113.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 PRP76844.1 - 1e-11 45.1 0.0 4.5e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP76844.1 - 3.8e-09 36.9 0.0 9.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP76844.1 - 2.6e-07 30.6 0.1 6.8e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PRP76844.1 - 0.0066 16.8 0.0 0.029 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain WD40 PF00400.32 PRP76845.1 - 2.7e-18 66.0 13.4 0.00031 21.5 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Sof1 PF04158.14 PRP76845.1 - 1.7e-13 50.6 12.3 1.7e-13 50.6 12.3 2.2 2 0 0 2 2 2 1 Sof1-like domain ANAPC4_WD40 PF12894.7 PRP76845.1 - 7.1e-06 26.2 1.3 1.8 8.9 0.0 4.8 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP76845.1 - 7e-05 22.8 0.8 0.084 12.7 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PRP76845.1 - 0.45 9.1 7.7 4.1 5.9 0.8 3.3 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Sod_Ni PF09055.11 PRP76845.1 - 1.2 9.7 5.8 1.8 9.1 4.3 1.9 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase Pkinase_Tyr PF07714.17 PRP76846.1 - 2.2e-53 181.2 0.3 5.3e-53 179.9 0.0 1.8 2 0 0 2 2 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76846.1 - 8e-45 153.2 0.0 2.3e-44 151.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain BRCT PF00533.26 PRP76846.1 - 2.5e-14 53.4 0.4 1.2e-10 41.6 0.3 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain SH2 PF00017.24 PRP76846.1 - 1e-10 41.5 0.0 3.5e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 SH2 domain PTCB-BRCT PF12738.7 PRP76846.1 - 1.9e-09 37.3 0.9 3.1e-08 33.4 0.8 2.4 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 PRP76846.1 - 4.3e-09 36.7 0.1 1.5e-05 25.3 0.2 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 PRP76846.1 - 1.3e-08 34.6 0.0 3.3e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Zn_clus PF00172.18 PRP76846.1 - 7.9e-06 25.9 7.6 1.5e-05 25.1 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haspin_kinase PF12330.8 PRP76846.1 - 0.096 11.6 9.7 0.52 9.2 0.0 3.1 4 0 0 4 4 4 0 Haspin like kinase domain LIG3_BRCT PF16759.5 PRP76846.1 - 0.18 12.2 0.2 0.41 11.0 0.2 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Lig_C PF18330.1 PRP76846.1 - 0.34 10.9 2.6 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Ligase Pab1020 C-terminal region DTW PF03942.15 PRP76847.1 - 2.2e-31 109.2 0.0 3.2e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.24 PRP76847.1 - 0.55 10.4 3.2 0.93 9.7 3.2 1.3 1 0 0 1 1 1 0 B-box zinc finger Complex1_LYR PF05347.15 PRP76848.1 - 4.1e-09 36.4 1.4 5.9e-09 35.8 1.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 PRP76848.1 - 0.0019 18.8 0.5 0.0023 18.5 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 PRP76848.1 - 0.032 15.0 0.5 0.039 14.7 0.5 1.2 1 0 0 1 1 1 0 Complex1_LYR-like BRO1 PF03097.18 PRP76849.1 - 1.4e-21 76.7 0.2 1.8e-21 76.4 0.2 1.0 1 0 0 1 1 1 1 BRO1-like domain Pkinase PF00069.25 PRP76851.1 - 6e-09 35.7 1.3 1.9e-08 34.0 1.3 1.8 1 0 0 1 1 1 1 Protein kinase domain Caldesmon PF02029.15 PRP76851.1 - 1.3e-05 24.2 30.0 1.8e-05 23.7 30.0 1.2 1 0 0 1 1 1 1 Caldesmon SDA1 PF05285.12 PRP76851.1 - 0.00034 20.2 32.6 0.00067 19.2 32.6 1.5 1 0 0 1 1 1 1 SDA1 MDM1 PF15501.6 PRP76851.1 - 0.038 13.2 24.3 0.057 12.6 24.3 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 DUF4045 PF13254.6 PRP76851.1 - 0.17 11.5 17.9 0.26 10.9 17.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Borrelia_P83 PF05262.11 PRP76851.1 - 0.69 8.3 21.3 0.98 7.8 21.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PI3K_1B_p101 PF10486.9 PRP76851.1 - 1.1 6.9 14.5 0.34 8.6 11.6 1.4 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 PRP76851.1 - 2.1 7.0 24.0 3.2 6.4 24.0 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 PRP76851.1 - 3.3 6.6 16.8 5.3 5.9 16.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 CDC27 PF09507.10 PRP76851.1 - 3.8 6.8 36.4 5.6 6.2 36.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 PRP76851.1 - 5.2 5.1 44.4 8 4.5 44.4 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_9 PF12781.7 PRP76853.1 - 0.001 18.2 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 ATP-binding dynein motor region Pkinase_Tyr PF07714.17 PRP76854.1 - 2.3e-60 204.1 0.0 3.5e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76854.1 - 4.3e-36 124.6 0.0 7.2e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PRP76854.1 - 0.0021 17.1 0.1 0.0044 16.0 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP76854.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase EPTP PF03736.17 PRP76854.1 - 0.17 11.9 1.1 12 6.0 0.1 3.1 2 0 0 2 2 2 0 EPTP domain Pkinase_Tyr PF07714.17 PRP76855.1 - 2e-69 233.8 0.0 3.1e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76855.1 - 5.2e-49 167.0 0.0 7.4e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SKG6 PF08693.10 PRP76855.1 - 4.9e-05 22.6 0.4 0.00013 21.3 0.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kdo PF06293.14 PRP76855.1 - 0.0026 17.1 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP76855.1 - 0.024 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PRP76855.1 - 0.052 12.3 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF2681 PF10883.8 PRP76855.1 - 0.052 14.0 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Pkinase_Tyr PF07714.17 PRP76856.1 - 6.1e-33 114.2 0.5 2.2e-26 92.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP76856.1 - 2.2e-18 66.6 0.3 3e-11 43.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Syndecan PF01034.20 PRP76856.1 - 0.061 13.2 0.7 0.18 11.8 0.7 1.7 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 PRP76857.1 - 3.6e-06 26.3 1.1 8.5e-06 25.1 1.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_Tyr PF07714.17 PRP76857.1 - 0.00018 20.9 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76857.1 - 0.00033 20.1 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF2567 PF10821.8 PRP76857.1 - 0.028 14.5 0.1 0.76 9.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) DUF4448 PF14610.6 PRP76857.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Zn_clus PF00172.18 PRP76858.1 - 8.3e-08 32.2 9.3 8.3e-08 32.2 9.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4720 PF15846.5 PRP76858.1 - 0.06 13.2 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) PSI_integrin PF17205.3 PRP76858.1 - 0.45 10.3 5.8 5.1 6.9 1.1 2.5 1 1 1 2 2 2 0 Integrin plexin domain Methyltr_RsmB-F PF01189.17 PRP76859.1 - 4.8e-43 147.1 0.0 7.4e-41 140.0 0.0 2.1 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 PRP76859.1 - 1.5e-09 37.8 0.0 2.7e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 PRP76859.1 - 0.00016 21.8 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 PRP76859.1 - 0.005 16.2 0.0 0.047 13.0 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Fibrillarin PF01269.17 PRP76859.1 - 0.077 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin Cons_hypoth95 PF03602.15 PRP76859.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 PRP76859.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mito_carr PF00153.27 PRP76860.1 - 2.5e-68 226.0 2.7 1.7e-21 76.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Exo_endo_phos PF03372.23 PRP76861.1 - 4.3e-09 36.2 0.1 1e-08 35.0 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_2 PF12796.7 PRP76862.1 - 1e-17 64.5 0.1 2e-10 41.1 0.1 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP76862.1 - 4.4e-13 49.2 1.0 1.1e-05 25.6 0.1 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP76862.1 - 9.5e-12 45.2 0.1 3.8e-05 24.2 0.0 4.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76862.1 - 1.1e-11 43.9 1.8 4.2e-05 23.6 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 PRP76862.1 - 2.7e-10 40.2 2.5 1.6e-07 31.4 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat F-box-like PF12937.7 PRP76862.1 - 3.8e-05 23.5 3.0 8e-05 22.5 3.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP76862.1 - 0.00066 19.5 1.1 0.0015 18.3 1.1 1.7 1 0 0 1 1 1 1 F-box domain Mpp10 PF04006.12 PRP76862.1 - 0.0016 17.0 27.6 0.0022 16.5 27.6 1.1 1 0 0 1 1 1 1 Mpp10 protein Paf1 PF03985.13 PRP76862.1 - 0.0085 15.1 23.5 0.014 14.5 23.5 1.4 1 0 0 1 1 1 1 Paf1 BUD22 PF09073.10 PRP76862.1 - 0.014 14.8 22.9 0.025 14.0 22.9 1.4 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 PRP76862.1 - 0.042 13.3 31.3 0.077 12.4 31.3 1.4 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PRP76862.1 - 0.045 12.0 32.4 0.062 11.5 32.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2722 PF10846.8 PRP76862.1 - 1.3 7.9 9.9 2.1 7.2 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PTPRCAP PF15713.5 PRP76862.1 - 3.1 8.1 32.3 6.5 7.0 32.3 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TFIIF_alpha PF05793.12 PRP76862.1 - 4.7 5.7 34.2 7 5.1 34.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BSP_II PF05432.11 PRP76862.1 - 7.6 6.1 39.2 15 5.2 39.2 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RR_TM4-6 PF06459.12 PRP76862.1 - 9.4 6.0 22.1 15 5.3 22.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 PRP76863.1 - 0.00019 20.1 27.1 0.00023 19.8 27.1 1.2 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 PRP76863.1 - 0.0064 14.8 32.3 0.0084 14.4 32.3 1.2 1 0 0 1 1 1 1 Nop14-like family Na_trans_assoc PF06512.13 PRP76863.1 - 0.19 12.0 19.3 0.29 11.4 19.3 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated TFIIF_alpha PF05793.12 PRP76863.1 - 0.43 9.1 32.4 0.67 8.5 32.4 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Drc1-Sld2 PF11719.8 PRP76863.1 - 1 8.8 19.4 1.3 8.5 19.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Zip PF02535.22 PRP76863.1 - 3.8 6.6 10.9 4.8 6.3 10.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 PRP76863.1 - 4.6 5.9 13.0 5.4 5.7 13.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 PRP76863.1 - 5.4 6.8 23.2 9.1 6.0 23.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Exo_endo_phos PF03372.23 PRP76864.1 - 4.3e-09 36.2 0.1 1e-08 35.0 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mito_carr PF00153.27 PRP76865.1 - 2.5e-68 226.0 2.7 1.7e-21 76.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltr_RsmB-F PF01189.17 PRP76866.1 - 3.9e-43 147.4 0.0 6.5e-41 140.2 0.0 2.1 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 PRP76866.1 - 1.5e-09 37.8 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 PRP76866.1 - 0.00013 22.1 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 PRP76866.1 - 0.0044 16.4 0.0 0.043 13.1 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PUA PF01472.20 PRP76866.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 PUA domain Fibrillarin PF01269.17 PRP76866.1 - 0.069 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Fibrillarin Cons_hypoth95 PF03602.15 PRP76866.1 - 0.092 12.4 0.0 0.28 10.8 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 PRP76866.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Zn_clus PF00172.18 PRP76867.1 - 1e-07 32.0 9.3 2.7e-07 30.6 9.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4720 PF15846.5 PRP76867.1 - 0.12 12.3 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4720) Proteasome PF00227.26 PRP76868.1 - 2.5e-56 190.2 0.4 3.7e-56 189.6 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PRP76868.1 - 6.4e-14 51.3 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature HATPase_c PF02518.26 PRP76869.1 - 2.6e-42 143.8 7.0 1.7e-23 83.2 0.8 3.7 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP76869.1 - 3.2e-25 88.5 0.1 1.6e-16 60.5 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 PRP76869.1 - 2e-23 82.2 0.8 3.4e-11 43.0 0.1 2.8 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 PRP76869.1 - 9.7e-07 29.2 0.0 1.1e-05 25.7 0.0 2.6 3 0 0 3 3 3 1 GAF domain HATPase_c_3 PF13589.6 PRP76869.1 - 6e-06 26.1 0.5 0.035 13.9 0.1 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 PRP76869.1 - 0.00037 20.5 0.1 0.45 10.5 0.0 2.9 2 0 0 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 PRP76869.1 - 0.00037 20.3 0.2 0.25 11.2 0.0 3.4 3 0 0 3 3 3 1 GHKL domain GAF PF01590.26 PRP76869.1 - 0.046 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 GAF domain GAF_3 PF13492.6 PRP76869.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 GAF domain GBP PF02263.19 PRP76870.1 - 9.9e-32 110.2 0.0 9.9e-32 110.2 0.0 5.0 5 1 0 5 5 5 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 PRP76870.1 - 1.1e-05 25.0 0.2 1.1e-05 25.0 0.2 6.9 2 1 4 7 7 7 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 PRP76870.1 - 0.0073 16.4 0.2 0.18 11.9 0.0 3.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase adh_short_C2 PF13561.6 PRP76870.1 - 0.61 9.6 4.2 0.16 11.5 0.2 2.1 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase DUF2278 PF10042.9 PRP76870.1 - 1.2 9.1 9.5 0.25 11.3 4.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2278) Baculo_PEP_C PF04513.12 PRP76870.1 - 9.8 6.2 40.5 4.1 7.4 3.4 7.0 3 2 4 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus MJ1316 PF04457.12 PRP76872.1 - 3.1e-22 79.1 1.4 4.8e-22 78.5 0.9 1.5 2 0 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain GLE1 PF07817.13 PRP76872.1 - 0.063 12.5 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 GLE1-like protein Ank_2 PF12796.7 PRP76873.1 - 7.1e-21 74.6 0.1 1.5e-11 44.7 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 PRP76873.1 - 1e-17 63.7 0.8 6.7e-08 32.6 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 PRP76873.1 - 2.2e-13 49.1 0.1 1.5e-05 25.0 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 PRP76873.1 - 3.4e-12 46.6 1.7 3.2e-05 24.4 0.0 5.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP76873.1 - 4.1e-11 42.9 1.9 0.0069 16.7 0.1 5.7 6 1 1 7 7 7 3 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP76873.1 - 0.0012 18.7 3.7 0.0025 17.7 1.8 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP76873.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 F-box domain PIN7 PF18475.1 PRP76875.1 - 0.00074 20.1 0.2 0.0049 17.5 0.1 2.5 2 1 1 3 3 3 1 PIN domain BST2 PF16716.5 PRP76875.1 - 0.044 14.4 5.5 0.11 13.1 5.5 1.7 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Cytochrom_B562 PF07361.11 PRP76875.1 - 0.046 14.4 1.3 3 8.5 0.4 2.8 2 0 0 2 2 2 0 Cytochrome b562 p450 PF00067.22 PRP76875.1 - 0.17 10.6 5.0 1.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Cytochrome P450 CENP-H PF05837.12 PRP76875.1 - 1.3 9.5 11.3 0.2 12.1 5.4 2.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Cytochrome_CBB3 PF13442.6 PRP76877.1 - 0.00021 21.6 8.8 0.33 11.3 0.3 3.8 2 1 1 3 3 3 2 Cytochrome C oxidase, cbb3-type, subunit III DUF3348 PF11828.8 PRP76877.1 - 0.0048 16.6 4.8 0.5 10.0 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3348) Phage_Mu_Gp45 PF06890.12 PRP76877.1 - 0.094 12.5 0.0 24 4.7 0.0 2.6 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein Ribosomal_L20 PF00453.18 PRP76877.1 - 0.35 11.0 8.2 15 5.8 0.1 3.9 3 1 0 3 3 3 0 Ribosomal protein L20 Cas_CXXC_CXXC PF09706.10 PRP76877.1 - 3 8.1 20.5 3.9 7.8 0.2 4.5 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_CXXC_CXXC) Pkinase_Tyr PF07714.17 PRP76879.1 - 3.3e-56 190.4 0.0 4.8e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76879.1 - 1.3e-51 175.5 0.0 2.6e-51 174.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP76879.1 - 0.035 14.0 0.1 0.059 13.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP76879.1 - 0.044 12.7 0.4 7.3 5.4 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain SPACA9 PF15120.6 PRP76881.1 - 0.091 12.5 0.0 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 DUF957 PF06117.11 PRP76881.1 - 2 8.0 3.7 17 5.1 0.3 2.4 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) Pkinase PF00069.25 PRP76882.1 - 5.6e-25 88.2 0.1 5.6e-25 88.2 0.1 2.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP76882.1 - 1.9e-10 40.5 0.0 3.8e-09 36.2 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase DUF4973 PF16343.5 PRP76882.1 - 0.035 14.2 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4973) C1_2 PF03107.16 PRP76882.1 - 0.21 11.9 3.1 0.66 10.3 3.1 1.9 1 0 0 1 1 1 0 C1 domain DUF1664 PF07889.12 PRP76882.1 - 6.3 6.9 7.8 2.1 8.4 4.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_8kDa PF06096.11 PRP76883.1 - 0.036 14.2 0.2 0.09 12.9 0.2 1.7 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein Pkinase_Tyr PF07714.17 PRP76885.1 - 1.7e-62 211.0 0.0 2.6e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76885.1 - 3.8e-41 141.2 0.0 7e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Beta_helix PF13229.6 PRP76885.1 - 2.2e-12 47.1 101.1 0.00027 20.8 27.8 7.1 2 2 4 7 7 7 6 Right handed beta helix region Chlam_PMP PF02415.17 PRP76885.1 - 0.0063 16.9 0.6 0.0063 16.9 0.6 13.5 15 0 0 15 15 15 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kdo PF06293.14 PRP76885.1 - 0.0097 15.3 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP76885.1 - 0.013 14.3 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 PRP76886.1 - 8.3e-31 105.6 0.0 2.6e-14 52.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 PRP76886.1 - 0.013 15.5 0.0 0.08 12.9 0.0 2.0 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PRP76886.1 - 0.021 14.9 0.0 0.077 13.1 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif FlxA PF14282.6 PRP76886.1 - 0.15 12.1 4.2 0.28 11.2 4.2 1.3 1 0 0 1 1 1 0 FlxA-like protein LRR_4 PF12799.7 PRP76887.1 - 3e-06 27.5 39.3 0.029 14.8 1.8 8.6 6 3 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP76887.1 - 2.4e-05 24.0 25.5 0.00053 19.7 0.9 6.1 4 3 2 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 PRP76887.1 - 0.0003 20.6 20.1 1.6 8.9 0.4 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 PRP76887.1 - 2.1 9.2 25.2 26 5.9 0.2 8.8 9 1 0 9 9 9 0 Leucine Rich Repeat Peptidase_M28 PF04389.17 PRP76888.1 - 6.1e-36 124.0 0.0 9e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PEN-2 PF10251.9 PRP76888.1 - 2.4 8.6 5.2 22 5.6 3.4 3.1 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Cullin_binding PF03556.15 PRP76889.1 - 1.3e-23 83.7 7.6 1.3e-23 83.7 7.6 2.1 3 0 0 3 3 3 1 Cullin binding SPRY PF00622.28 PRP76889.1 - 4.6e-20 71.9 0.5 2.1e-19 69.8 0.3 2.1 2 0 0 2 2 2 1 SPRY domain C2 PF00168.30 PRP76889.1 - 1.1e-13 51.4 0.2 3.3e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 C2 domain SH3_9 PF14604.6 PRP76890.1 - 0.00032 20.5 0.5 0.00055 19.7 0.5 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP76890.1 - 0.0029 17.3 0.1 0.0048 16.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP76890.1 - 0.0051 16.4 0.6 0.01 15.4 0.6 1.5 1 0 0 1 1 1 1 SH3 domain Utp13 PF08625.11 PRP76891.1 - 5e-28 97.8 1.1 9.8e-28 96.8 1.1 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain BUD22 PF09073.10 PRP76891.1 - 0.015 14.7 22.4 0.016 14.6 22.4 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 PRP76891.1 - 0.032 12.7 21.1 0.033 12.7 21.1 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF2201_N PF13203.6 PRP76891.1 - 0.17 11.4 2.2 0.18 11.3 2.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.15 PRP76891.1 - 1.2 7.8 6.7 1.3 7.7 6.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PhoU PF01895.19 PRP76891.1 - 1.4 9.5 8.7 0.68 10.4 6.0 1.9 2 1 0 2 2 2 0 PhoU domain V_ATPase_I PF01496.19 PRP76891.1 - 4.7 5.0 5.0 5.5 4.8 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RP-C_C PF11800.8 PRP76891.1 - 5.1 7.1 6.6 8 6.5 6.6 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Ceramidase PF05875.12 PRP76892.1 - 2.1e-53 181.5 25.7 2e-52 178.3 25.7 2.0 1 1 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 PRP76892.1 - 0.055 13.4 1.6 0.18 11.8 1.6 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide Sec62 PF03839.16 PRP76892.1 - 6.6 6.2 16.6 0.76 9.2 0.1 2.4 2 0 0 2 2 2 0 Translocation protein Sec62 RT_RNaseH PF17917.1 PRP76895.1 - 1.1e-34 118.9 0.0 2.4e-34 117.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP76895.1 - 2.6e-31 107.6 0.0 7.5e-31 106.1 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP76895.1 - 2.3e-29 102.5 0.6 3.7e-29 101.8 0.1 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 PRP76895.1 - 2.8e-18 65.8 0.4 7.4e-18 64.4 0.4 1.8 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP76895.1 - 8.4e-14 51.8 0.0 2.9e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 PRP76895.1 - 7.2e-09 35.4 0.4 2.3e-08 33.8 0.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 PRP76895.1 - 0.00078 19.6 0.2 0.002 18.3 0.2 1.8 1 0 0 1 1 1 1 H2C2 zinc finger Cytochrome_CBB3 PF13442.6 PRP76895.1 - 0.02 15.2 0.0 4.5 7.7 0.0 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Apolipoprotein PF01442.18 PRP76895.1 - 0.48 10.3 2.3 0.44 10.4 0.2 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain zf-CCHC PF00098.23 PRP76896.1 - 4.1e-06 26.6 2.1 7.6e-06 25.8 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle gag-asp_proteas PF13975.6 PRP76896.1 - 0.0003 21.3 0.0 0.0037 17.8 0.0 2.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_6 PF15288.6 PRP76896.1 - 0.0076 16.1 0.6 0.019 14.8 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.6 PRP76896.1 - 0.015 16.0 0.2 0.042 14.5 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease eIF3g PF12353.8 PRP76896.1 - 0.022 15.2 0.4 0.075 13.4 0.4 1.9 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 PRP76896.1 - 0.022 14.7 1.8 0.046 13.7 1.8 1.5 1 0 0 1 1 1 0 Zinc knuckle Coagulin PF02035.15 PRP76896.1 - 0.038 13.9 0.2 0.081 12.8 0.2 1.5 1 0 0 1 1 1 0 Coagulin zf-CCHC_2 PF13696.6 PRP76896.1 - 0.098 12.5 1.8 0.23 11.3 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 PRP76896.1 - 0.3 10.9 1.1 0.55 10.0 1.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.17 PRP76898.1 - 8.3e-133 441.5 0.0 4.1e-67 226.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TIG PF01833.24 PRP76898.1 - 2.3e-109 357.7 404.2 3.6e-11 43.0 6.8 32.8 28 4 6 34 34 33 27 IPT/TIG domain Pkinase PF00069.25 PRP76898.1 - 2.4e-96 322.2 0.0 4.4e-47 160.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 PRP76898.1 - 6.3e-09 35.5 0.2 0.0025 17.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP76898.1 - 1.1e-07 31.0 0.1 0.0076 15.1 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Adeno_E3_CR2 PF02439.15 PRP76898.1 - 0.00015 21.5 13.1 0.0072 16.1 0.6 3.4 2 0 0 2 2 2 2 Adenovirus E3 region protein CR2 LRR_8 PF13855.6 PRP76898.1 - 0.00065 19.4 0.4 0.00065 19.4 0.4 3.4 2 1 2 4 4 4 3 Leucine rich repeat Kinase-like PF14531.6 PRP76898.1 - 0.001 18.5 0.0 0.25 10.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAN_4 PF14295.6 PRP76898.1 - 0.0011 18.8 1.8 0.0034 17.3 1.8 1.8 1 0 0 1 1 1 1 PAN domain Haspin_kinase PF12330.8 PRP76898.1 - 0.0092 15.0 0.4 0.51 9.2 0.0 2.6 3 0 0 3 3 3 1 Haspin like kinase domain EphA2_TM PF14575.6 PRP76898.1 - 0.013 16.4 2.7 4.5 8.2 0.2 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orthoreo_P10 PF07204.11 PRP76898.1 - 0.043 13.8 2.2 0.78 9.7 0.1 3.4 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 BatA PF07584.11 PRP76898.1 - 0.099 13.0 0.1 0.58 10.6 0.0 2.3 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal LRR_4 PF12799.7 PRP76898.1 - 0.13 12.8 12.4 0.33 11.4 1.9 4.2 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) LapA_dom PF06305.11 PRP76898.1 - 0.26 11.1 7.8 1.3 8.8 1.2 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain APH PF01636.23 PRP76898.1 - 0.47 10.3 1.1 9.3 6.1 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Gram_pos_anchor PF00746.21 PRP76898.1 - 0.92 9.5 3.1 7.7 6.6 0.3 3.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Aminotran_1_2 PF00155.21 PRP76899.1 - 1.3e-30 106.9 0.0 1.6e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 PRP76899.1 - 0.036 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 PRP76899.1 - 0.2 10.2 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_helix PF13229.6 PRP76902.1 - 2.2e-06 27.6 43.5 0.0004 20.3 8.8 6.3 2 2 3 6 6 6 4 Right handed beta helix region Phytochelatin_C PF09328.10 PRP76902.1 - 0.007 15.7 0.0 4.1 6.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1984) DUF2953 PF11167.8 PRP76902.1 - 0.036 14.1 2.0 71 3.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2953) Chlam_PMP PF02415.17 PRP76902.1 - 0.3 11.7 0.9 1.9 9.1 0.2 2.9 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ephrin_rec_like PF07699.13 PRP76902.1 - 1.1 9.1 22.4 1.8 8.4 1.1 5.0 4 0 0 4 4 4 0 Putative ephrin-receptor like Zn_clus PF00172.18 PRP76902.1 - 2.9 8.1 5.8 17 5.6 0.9 3.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NCD3G PF07562.14 PRP76902.1 - 5.1 7.1 24.6 0.11 12.5 0.3 4.1 4 0 0 4 4 4 0 Nine Cysteines Domain of family 3 GPCR ALG11_N PF15924.5 PRP76904.1 - 6.6e-75 251.7 0.3 5e-74 248.9 0.1 2.1 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus IFRD PF05004.13 PRP76904.1 - 1e-50 172.6 7.2 1.5e-50 172.0 7.2 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Glycos_transf_1 PF00534.20 PRP76904.1 - 5.8e-16 58.5 0.0 7.8e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 SET PF00856.28 PRP76905.1 - 3.5e-06 27.5 0.0 0.0024 18.3 0.0 3.1 2 2 1 3 3 3 2 SET domain DUF2283 PF10049.9 PRP76905.1 - 0.13 12.5 2.1 9.3 6.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) Leu_zip PF15294.6 PRP76906.1 - 6.2e-47 160.4 33.3 1.1e-35 123.5 11.8 2.0 1 1 1 2 2 2 2 Leucine zipper UPF0242 PF06785.11 PRP76906.1 - 0.014 15.5 13.2 0.014 15.5 13.2 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Sde2_N_Ubi PF13019.6 PRP76906.1 - 0.02 14.7 9.8 0.062 13.1 9.8 1.9 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain WDCP PF15390.6 PRP76906.1 - 1.6 7.0 14.7 2.3 6.5 14.7 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family HAUS-augmin3 PF14932.6 PRP76906.1 - 3.6 7.1 25.9 0.25 10.9 7.3 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 UPF0449 PF15136.6 PRP76906.1 - 5.2 7.6 18.1 0.88 10.1 3.5 3.4 2 1 0 3 3 3 0 Uncharacterised protein family UPF0449 DUF1664 PF07889.12 PRP76906.1 - 6.5 6.8 17.3 6.9 6.7 0.4 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) SH3_9 PF14604.6 PRP76907.1 - 3.7e-24 84.3 0.7 2.1e-11 43.5 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PRP76907.1 - 4e-22 77.6 0.3 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 PRP76907.1 - 9.3e-19 66.9 0.1 2.7e-10 39.8 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain WD40 PF00400.32 PRP76907.1 - 3.7e-17 62.4 18.1 0.00024 21.8 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Methyltransf_16 PF10294.9 PRP76907.1 - 1.4e-07 31.4 0.0 3.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 PRP76907.1 - 9.6e-07 28.7 0.0 4.5e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP76907.1 - 5.2e-06 26.4 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FCH PF00611.23 PRP76907.1 - 4.8e-05 23.6 0.4 4.8e-05 23.6 0.4 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Methyltransf_12 PF08242.12 PRP76907.1 - 0.00015 22.4 0.0 0.0016 19.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP76907.1 - 0.00026 21.7 0.0 0.0022 18.7 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain ANAPC4_WD40 PF12894.7 PRP76907.1 - 0.00028 21.1 0.2 2.4 8.5 0.0 4.7 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain MTS PF05175.14 PRP76907.1 - 0.0033 17.0 0.0 0.0093 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain PQQ_3 PF13570.6 PRP76907.1 - 0.01 16.3 1.5 3.4 8.3 0.1 4.0 5 0 0 5 5 4 0 PQQ-like domain MetW PF07021.12 PRP76907.1 - 0.028 14.0 0.1 11 5.6 0.0 2.9 2 1 0 2 2 2 0 Methionine biosynthesis protein MetW Spc7 PF08317.11 PRP76907.1 - 0.037 12.9 11.2 0.061 12.2 11.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 PRP76907.1 - 0.043 13.8 1.8 0.22 11.6 1.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TehB PF03848.14 PRP76907.1 - 0.056 12.8 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB Porin_OmpG PF09381.10 PRP76907.1 - 0.065 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) BBS2_Mid PF14783.6 PRP76907.1 - 0.12 12.5 0.0 0.84 9.7 0.0 2.4 3 0 0 3 3 2 0 Ciliary BBSome complex subunit 2, middle region Methyltransf_11 PF08241.12 PRP76907.1 - 0.12 13.0 0.0 0.58 10.8 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain Mit_KHE1 PF10173.9 PRP76907.1 - 0.16 12.0 0.1 0.16 12.0 0.1 2.3 2 1 1 3 3 2 0 Mitochondrial K+-H+ exchange-related Atg14 PF10186.9 PRP76907.1 - 0.42 9.7 7.0 1.1 8.3 7.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF745 PF05335.13 PRP76907.1 - 2 8.1 12.7 0.46 10.2 5.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Dzip-like_N PF13815.6 PRP76908.1 - 3.2e-24 85.2 3.3 3.2e-24 85.2 3.3 3.0 2 1 1 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal NCD3G PF07562.14 PRP76909.1 - 0.018 15.0 0.7 0.018 15.0 0.7 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 PRP76909.1 - 2.5 7.9 9.4 1.6 8.6 1.4 2.9 2 0 0 2 2 2 0 Putative ephrin-receptor like NCD3G PF07562.14 PRP76910.1 - 0.021 14.8 0.4 0.021 14.8 0.4 2.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Chlam_PMP PF02415.17 PRP76910.1 - 0.33 11.5 3.2 2.5 8.8 0.1 3.6 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ephrin_rec_like PF07699.13 PRP76910.1 - 0.67 9.8 7.8 2.2 8.1 0.7 3.0 2 0 0 2 2 2 0 Putative ephrin-receptor like Aldedh PF00171.22 PRP76911.1 - 5.7e-127 424.0 0.0 7.1e-127 423.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AhpC-TSA PF00578.21 PRP76912.1 - 3.4e-19 69.0 0.1 5.5e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PRP76912.1 - 1.4e-15 57.3 0.1 2.1e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 PRP76912.1 - 1.9e-15 57.0 0.1 3.5e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PRP76912.1 - 2.3e-11 43.6 0.5 1.4e-09 37.9 0.1 2.5 2 1 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.6 PRP76912.1 - 3e-06 27.6 0.2 6.9e-06 26.5 0.1 1.5 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 PRP76912.1 - 0.00093 19.0 0.0 0.34 10.7 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin HeH PF12949.7 PRP76912.1 - 0.0031 17.2 0.1 0.0052 16.5 0.1 1.3 1 0 0 1 1 1 1 HeH/LEM domain Glutaredoxin PF00462.24 PRP76912.1 - 0.0047 17.1 0.2 1.1 9.5 0.0 3.0 3 0 0 3 3 3 1 Glutaredoxin DUF899 PF05988.12 PRP76912.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) AhpC-TSA_2 PF13911.6 PRP76912.1 - 0.027 14.6 0.1 0.13 12.4 0.0 1.9 1 1 0 2 2 2 0 AhpC/TSA antioxidant enzyme Thioredoxin_7 PF13899.6 PRP76912.1 - 0.14 12.4 1.3 0.61 10.3 1.3 2.0 1 1 0 1 1 1 0 Thioredoxin-like Beta_helix PF13229.6 PRP76913.1 - 1.7e-05 24.7 13.3 0.00012 22.0 4.8 3.0 2 1 0 2 2 2 2 Right handed beta helix region NCD3G PF07562.14 PRP76913.1 - 0.011 15.7 0.4 0.011 15.7 0.4 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Chlam_PMP PF02415.17 PRP76913.1 - 0.6 10.7 2.4 2.8 8.6 0.2 3.0 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ephrin_rec_like PF07699.13 PRP76913.1 - 0.77 9.6 8.9 0.73 9.7 1.1 3.0 2 0 0 2 2 2 0 Putative ephrin-receptor like NCD3G PF07562.14 PRP76915.1 - 0.015 15.2 0.4 0.015 15.2 0.4 2.5 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 PRP76915.1 - 1.4 8.7 9.4 1 9.1 1.1 3.0 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-C3HC4 PF00097.25 PRP76917.1 - 2.3e-07 30.6 13.0 2.3e-07 30.6 13.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP76917.1 - 7.8e-07 29.2 15.0 7.8e-07 29.2 15.0 2.7 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PRP76917.1 - 2.2e-06 27.5 10.3 2.2e-06 27.5 10.3 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP76917.1 - 2.4e-06 27.3 12.4 2.4e-06 27.3 12.4 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP76917.1 - 2.7e-06 27.1 10.6 2.7e-06 27.1 10.6 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP76917.1 - 1.2e-05 25.5 12.0 1.2e-05 25.5 12.0 2.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PRP76917.1 - 0.00033 20.6 11.8 0.00033 20.6 11.8 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.24 PRP76917.1 - 0.0054 16.8 14.2 0.0054 16.8 14.2 3.4 2 2 0 2 2 2 1 B-box zinc finger Na_H_antiport_2 PF13726.6 PRP76917.1 - 0.19 11.9 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Na+-H+ antiporter family MTP18 PF10558.9 PRP76918.1 - 3.2e-57 193.2 10.2 2.2e-28 99.4 2.8 2.2 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) WBS_methylT PF12589.8 PRP76919.1 - 4.4e-20 72.2 10.0 7.2e-20 71.5 10.0 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 PRP76919.1 - 1.5e-10 41.6 0.0 2.6e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP76919.1 - 2.2e-10 41.1 0.0 4.8e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP76919.1 - 0.0001 23.0 0.0 0.0003 21.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP76919.1 - 0.00032 20.6 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP76919.1 - 0.00087 19.1 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP76919.1 - 0.018 14.4 0.5 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 PRP76919.1 - 0.038 13.3 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 PRP76919.1 - 0.088 12.8 0.3 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain N6_N4_Mtase PF01555.18 PRP76919.1 - 0.12 12.1 2.5 0.54 9.9 0.0 2.4 2 1 0 2 2 2 0 DNA methylase PCMT PF01135.19 PRP76919.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BING4CT PF08149.11 PRP76920.1 - 2.6e-30 104.0 3.3 2.2e-28 97.9 0.0 4.2 5 0 0 5 5 5 1 BING4CT (NUC141) domain WD40 PF00400.32 PRP76920.1 - 3.6e-06 27.6 0.0 0.00019 22.2 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP76920.1 - 1.7e-05 25.1 0.0 0.29 11.5 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 PRP76921.1 - 1.4e-35 119.6 31.5 6.8e-06 25.7 0.1 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 PRP76921.1 - 1.6e-33 112.1 27.9 8.4e-05 22.4 0.1 11.6 12 1 1 13 13 12 7 Tetratricopeptide repeat TPR_12 PF13424.6 PRP76921.1 - 3.5e-27 94.5 17.6 3.7e-09 36.7 0.0 8.0 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 PRP76921.1 - 1.1e-22 80.4 3.0 7.6e-08 32.9 0.0 7.8 8 1 0 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP76921.1 - 5.5e-22 76.1 36.3 0.0011 19.0 0.0 11.3 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_6 PF13174.6 PRP76921.1 - 1.4e-19 69.3 16.4 0.00051 20.5 0.4 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 PRP76921.1 - 1.4e-18 67.1 14.5 2.5e-06 27.9 0.2 7.5 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 PRP76921.1 - 7.4e-18 63.7 4.0 0.17 12.8 0.0 8.7 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 PRP76921.1 - 4.1e-17 60.9 15.6 0.0011 18.8 0.1 9.2 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 PRP76921.1 - 2.3e-15 56.0 17.9 4.9e-07 29.3 0.2 8.0 9 0 0 9 9 8 3 TPR repeat TPR_17 PF13431.6 PRP76921.1 - 1.3e-13 50.3 22.7 0.2 12.1 0.1 9.9 10 1 0 10 10 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP76921.1 - 4.1e-11 43.0 17.8 0.0044 17.2 0.4 6.1 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 PRP76921.1 - 3e-10 40.1 9.3 5.7e-05 22.9 3.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 PRP76921.1 - 1.2e-07 31.8 3.2 0.0081 16.3 0.3 4.8 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP76921.1 - 1.7e-06 27.7 0.7 0.04 13.3 0.0 3.6 3 2 1 4 4 4 3 MalT-like TPR region TPR_15 PF13429.6 PRP76921.1 - 2.1e-05 23.9 12.6 0.00018 20.8 5.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP76921.1 - 6.3e-05 23.0 16.1 0.062 13.4 0.2 6.2 7 0 0 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 PRP76921.1 - 0.00017 20.5 6.0 0.0015 17.3 0.4 2.8 3 1 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_10 PF13374.6 PRP76921.1 - 0.00026 20.8 22.5 0.062 13.2 0.1 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF3856 PF12968.7 PRP76921.1 - 0.0018 18.3 6.5 11 6.1 0.1 4.9 3 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 PRP76921.1 - 0.022 15.1 7.0 0.13 12.6 0.0 4.7 4 2 2 6 6 5 0 Tetratricopeptide repeat DUF4919 PF16266.5 PRP76921.1 - 0.048 13.6 0.1 0.048 13.6 0.1 3.7 3 2 1 4 4 3 0 Domain of unknown function (DUF4919) Rapsyn_N PF10579.9 PRP76921.1 - 0.1 12.7 2.0 0.76 9.9 0.1 3.3 3 1 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TAF1_subA PF14929.6 PRP76921.1 - 0.21 10.9 2.4 6.3 6.1 2.2 3.1 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A Foie-gras_1 PF11817.8 PRP76921.1 - 0.65 9.5 3.8 7.7 6.0 0.0 3.7 3 1 2 5 5 5 0 Foie gras liver health family 1 SPO22 PF08631.10 PRP76921.1 - 0.73 9.3 5.4 1.5 8.2 0.0 3.4 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 PRP76921.1 - 1.1 9.4 19.8 1.6 8.9 0.0 6.4 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain NSF PF02071.20 PRP76921.1 - 9.7 7.5 7.4 5.6e+02 2.2 0.1 5.8 5 0 0 5 5 3 0 Aromatic-di-Alanine (AdAR) repeat Abhydrolase_3 PF07859.13 PRP76922.1 - 1e-53 182.4 0.0 1.8e-53 181.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HSL_N PF06350.12 PRP76922.1 - 2.6e-22 79.2 0.0 4.1e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus Say1_Mug180 PF10340.9 PRP76922.1 - 1.8e-06 27.1 0.0 3.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 PRP76922.1 - 0.035 13.4 0.0 0.41 9.9 0.0 2.3 1 1 0 2 2 2 0 Serine aminopeptidase, S33 LIG3_BRCT PF16759.5 PRP76922.1 - 0.077 13.3 0.3 0.34 11.2 0.1 2.1 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain DLH PF01738.18 PRP76922.1 - 0.091 12.3 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family COesterase PF00135.28 PRP76922.1 - 0.16 10.8 1.5 1.7 7.4 0.3 2.6 2 1 0 2 2 2 0 Carboxylesterase family Bax1-I PF01027.20 PRP76923.1 - 2.4e-36 125.5 27.5 2.8e-36 125.3 27.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 ATP1G1_PLM_MAT8 PF02038.16 PRP76923.1 - 0.19 11.2 2.9 2.8 7.4 0.4 3.0 2 1 1 3 3 3 0 ATP1G1/PLM/MAT8 family BaxI_1 PF12811.7 PRP76923.1 - 0.92 9.0 24.0 1.8 8.1 24.0 1.5 1 1 0 1 1 1 0 Bax inhibitor 1 like TRAPP PF04051.16 PRP76924.1 - 1.3e-39 135.3 0.0 1.6e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Arc PF03869.14 PRP76924.1 - 0.092 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Arc-like DNA binding domain Adeno_terminal PF02459.15 PRP76924.1 - 0.1 11.0 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Pkinase_Tyr PF07714.17 PRP76925.1 - 4.1e-34 118.0 0.0 5.8e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP76925.1 - 6e-34 115.6 56.9 3.7e-08 33.0 3.1 8.8 7 2 1 8 8 8 6 Leucine rich repeat Pkinase PF00069.25 PRP76925.1 - 3.9e-27 95.3 0.1 6.5e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP76925.1 - 1.3e-18 66.8 71.0 0.00031 21.1 0.2 11.2 6 3 3 11 11 11 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP76925.1 - 1e-11 43.7 52.0 0.079 13.5 0.1 17.1 18 0 0 18 18 18 5 Leucine Rich Repeat GPS PF01825.21 PRP76925.1 - 6.6e-10 39.4 4.7 1.5e-09 38.2 4.7 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_6 PF13516.6 PRP76925.1 - 0.28 11.3 0.1 0.28 11.3 0.1 10.6 11 0 0 11 11 11 0 Leucine Rich repeat Pkinase_Tyr PF07714.17 PRP76926.1 - 1.6e-33 116.1 0.2 2.2e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76926.1 - 3.5e-27 95.4 0.7 5.4e-27 94.8 0.7 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP76926.1 - 2.4e-26 91.3 60.3 9.5e-07 28.5 7.9 8.8 6 2 4 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 PRP76926.1 - 8.5e-15 54.6 68.4 1.6e-05 25.2 0.9 9.7 5 3 3 10 10 10 6 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP76926.1 - 5.6e-10 39.6 4.7 1.5e-09 38.3 4.7 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP76926.1 - 1.2e-06 28.2 54.1 0.44 11.3 0.1 15.1 16 0 0 16 16 16 3 Leucine Rich Repeat Ank_4 PF13637.6 PRP76927.1 - 9.5e-05 22.9 0.2 0.031 14.9 0.0 4.3 4 2 0 4 4 4 1 Ankyrin repeats (many copies) F-box PF00646.33 PRP76927.1 - 0.019 14.8 0.2 0.14 12.0 0.0 2.6 3 0 0 3 3 3 0 F-box domain Pkinase_Tyr PF07714.17 PRP76928.1 - 2.5e-37 128.6 0.2 3.5e-37 128.1 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP76928.1 - 2e-26 91.5 53.1 9.8e-07 28.5 6.5 10.3 6 3 4 10 10 10 7 Leucine rich repeat Pkinase PF00069.25 PRP76928.1 - 5.3e-26 91.6 0.2 8.1e-26 91.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP76928.1 - 9e-18 64.1 58.2 6.3e-06 26.4 0.9 11.5 8 2 3 12 12 12 7 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP76928.1 - 7.2e-10 39.2 4.7 1.8e-09 37.9 4.7 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP76928.1 - 3.4e-07 29.9 49.0 1.3 9.9 0.1 14.9 16 1 0 16 16 16 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP76928.1 - 0.28 11.3 0.0 0.28 11.3 0.0 9.9 12 0 0 12 12 12 0 Leucine Rich repeat Orf78 PF06024.12 PRP76928.1 - 0.39 11.1 1.0 0.86 9.9 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Bac_rhamnosid6H PF17389.2 PRP76929.1 - 1e-12 48.0 0.8 1.1e-11 44.6 0.6 2.4 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 PRP76929.1 - 0.00068 18.7 0.8 0.12 11.3 0.1 2.1 1 1 1 2 2 2 2 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 PRP76929.1 - 0.011 14.6 0.7 0.026 13.4 0.1 1.8 2 0 0 2 2 2 0 Trehalase Acyltransf_C PF16076.5 PRP76930.1 - 0.0094 16.0 0.4 0.044 13.9 0.4 2.1 1 1 0 1 1 1 1 Acyltransferase C-terminus NRDE-2 PF08424.10 PRP76931.1 - 3.5e-71 240.0 4.1 3.5e-71 240.0 4.1 2.8 4 0 0 4 4 4 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 PRP76931.1 - 6.1e-06 26.6 6.3 0.27 12.2 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 PRP76931.1 - 8.9e-06 25.1 0.1 0.0041 16.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PRP76931.1 - 0.00012 22.0 1.1 0.17 11.9 0.0 4.2 3 1 1 4 4 4 1 Mad3/BUB1 homology region 1 TPR_11 PF13414.6 PRP76931.1 - 0.0013 18.4 0.2 0.47 10.2 0.0 3.3 3 0 0 3 3 3 1 TPR repeat Mso1_Sec1_bdg PF14475.6 PRP76931.1 - 0.061 12.9 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Sec1-binding region of Mso1 TPR_19 PF14559.6 PRP76931.1 - 0.093 13.3 0.6 58 4.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.14 PRP76931.1 - 0.31 11.0 0.0 0.31 11.0 0.0 4.2 5 1 0 5 5 5 0 Suppressor of forked protein (Suf) TPR_12 PF13424.6 PRP76931.1 - 1.5 9.2 4.9 0.43 10.9 0.1 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MDMPI_N PF11716.8 PRP76931.1 - 5.9 7.6 7.0 1.6 9.4 0.5 2.7 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Cofilin_ADF PF00241.20 PRP76932.1 - 6.2e-39 132.5 0.0 8e-39 132.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AD PF09793.9 PRP76933.1 - 2.1e-25 88.7 0.1 3.1e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 PRP76933.1 - 0.00013 21.6 0.4 0.0015 18.1 0.4 2.1 1 1 0 1 1 1 1 Gemin6 protein RICTOR_N PF14664.6 PRP76934.1 - 6.2e-76 255.8 0.0 1.7e-75 254.3 0.0 1.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 PRP76934.1 - 4.7e-27 93.8 0.1 5.4e-24 84.0 0.0 3.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 PRP76934.1 - 6.6e-27 93.5 2.7 1.4e-21 76.5 0.2 4.8 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 PRP76934.1 - 1.3e-23 83.4 0.6 3.7e-21 75.6 0.0 3.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 PRP76934.1 - 0.02 15.1 0.8 17 6.0 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat HEAT_PBS PF03130.16 PRP76934.1 - 0.032 14.9 0.2 0.62 10.9 0.0 3.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 PRP76934.1 - 0.1 13.1 0.4 0.71 10.4 0.1 2.7 2 1 0 2 2 2 0 HEAT-like repeat Arm PF00514.23 PRP76935.1 - 0.13 12.4 0.2 0.44 10.7 0.2 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat F-box-like PF12937.7 PRP76935.1 - 0.22 11.4 3.2 0.13 12.2 0.4 2.2 2 0 0 2 2 2 0 F-box-like ATP_bind_1 PF03029.17 PRP76936.1 - 1.4e-26 93.7 0.2 2.7e-26 92.8 0.2 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein SF-assemblin PF06705.11 PRP76936.1 - 1.2 8.4 4.8 0.28 10.5 1.4 1.6 2 1 0 2 2 2 0 SF-assemblin/beta giardin Gelsolin PF00626.22 PRP76937.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Gelsolin repeat EGF_2 PF07974.13 PRP76938.1 - 8.1e-06 26.1 31.9 0.0042 17.4 5.7 2.9 2 0 0 2 2 2 2 EGF-like domain Pkinase_Tyr PF07714.17 PRP76938.1 - 0.0004 19.7 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 PRP76939.1 - 5.2e-31 106.6 1.1 3.6e-08 33.8 0.0 5.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP76939.1 - 3.5e-30 104.4 2.8 2.4e-12 47.3 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PRP76939.1 - 3.1e-28 97.0 1.3 1e-05 25.7 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 PRP76939.1 - 5.8e-26 87.7 0.0 6.7e-05 23.0 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 PRP76939.1 - 1.8e-25 88.7 0.2 2.9e-08 33.8 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) ELMO_CED12 PF04727.13 PRP76939.1 - 2.1e-25 89.9 0.0 7.8e-16 58.7 0.0 2.8 2 1 0 2 2 2 2 ELMO/CED-12 family DUF3361 PF11841.8 PRP76939.1 - 1.6e-08 34.6 0.0 4.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) C2 PF00168.30 PRP76939.1 - 0.0076 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain SH2 PF00017.24 PRP76939.1 - 0.015 15.3 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 SH2 domain DUF4879 PF16219.5 PRP76939.1 - 0.039 14.2 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4879) Kelch_1 PF01344.25 PRP76941.1 - 8.8e-39 130.9 16.4 5.2e-09 35.5 0.1 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 PRP76941.1 - 1.1e-31 108.0 9.5 2.8e-06 27.4 0.1 6.3 2 2 4 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PRP76941.1 - 8.4e-24 83.3 9.9 2.4e-05 24.2 0.0 7.6 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP76941.1 - 1.8e-18 65.7 9.3 0.0028 17.6 0.0 6.6 5 1 1 6 6 6 5 Kelch motif BTB_2 PF02214.22 PRP76941.1 - 8.2e-17 61.4 0.0 1.6e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 PRP76941.1 - 3.3e-14 52.7 2.6 0.006 16.8 0.1 6.3 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP76941.1 - 7.2e-14 51.4 1.4 0.0091 16.0 0.1 5.4 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 PRP76941.1 - 0.0004 20.6 0.0 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4784 PF16023.5 PRP76941.1 - 0.11 11.4 0.0 0.71 8.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4784) Ras PF00071.22 PRP76942.1 - 8.2e-37 126.3 0.0 5.2e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PRP76942.1 - 4.6e-16 59.1 0.0 2.7e-07 30.8 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP76942.1 - 0.074 12.5 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_7 PF12775.7 PRP76942.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Tweety PF04906.13 PRP76942.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Tweety OPT PF03169.15 PRP76943.1 - 2.6e-159 531.7 62.6 3e-159 531.5 62.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 PRP76943.1 - 8.3 6.7 6.8 13 6.0 1.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Ephrin_rec_like PF07699.13 PRP76944.1 - 3.3 7.5 10.8 4.6 7.1 2.8 2.9 2 1 0 2 2 2 0 Putative ephrin-receptor like HNH_5 PF14279.6 PRP76945.1 - 1.1 9.2 3.9 12 5.8 0.3 2.5 2 0 0 2 2 2 0 HNH endonuclease Clathrin PF00637.20 PRP76946.1 - 1.6e-18 67.0 10.8 1.3e-13 51.0 3.8 3.0 2 0 0 2 2 2 2 Region in Clathrin and VPS VPS11_C PF12451.8 PRP76946.1 - 4.4e-14 52.4 1.0 4.4e-14 52.4 1.0 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 PRP76946.1 - 3.3e-06 27.0 8.7 6.5e-06 26.1 8.7 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 PRP76946.1 - 0.012 15.4 7.2 0.024 14.5 7.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP76946.1 - 0.04 14.3 6.7 0.1 12.9 6.7 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 PRP76946.1 - 0.043 13.7 1.1 0.11 12.4 1.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-HC5HC2H PF13771.6 PRP76946.1 - 0.18 12.0 2.9 0.74 10.1 2.9 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-Di19 PF05605.12 PRP76946.1 - 0.78 10.1 4.5 1.8 8.9 4.5 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.6 PRP76946.1 - 1.6 8.7 6.3 4.4 7.3 6.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 PRP76946.1 - 2.9 8.2 7.5 1.3 9.4 4.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP76946.1 - 6.3 6.9 6.4 18 5.4 6.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger CFAP91 PF14738.6 PRP76947.1 - 4.1e-30 104.9 6.2 4.1e-30 104.9 6.2 2.9 3 0 0 3 3 3 1 Cilia- and flagella-associated protein 91 LST1 PF05083.13 PRP76947.1 - 3.9 7.8 4.7 2 8.7 0.1 2.6 2 0 0 2 2 2 0 LST-1 protein RNF111_N PF15303.6 PRP76948.1 - 0.047 13.5 1.3 0.05 13.4 1.3 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus ATP_bind_1 PF03029.17 PRP76949.1 - 3.6e-49 167.7 0.0 6.2e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Kelch_1 PF01344.25 PRP76949.1 - 6.6e-24 83.2 20.1 1.2e-09 37.6 0.6 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 PRP76949.1 - 1.3e-21 76.3 18.6 2.5e-07 30.6 0.2 6.0 6 0 0 6 6 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP76949.1 - 1.9e-18 66.0 17.5 1.5e-06 28.3 0.3 6.4 4 2 2 6 6 6 4 Kelch motif Kelch_5 PF13854.6 PRP76949.1 - 1.1e-14 54.1 7.4 9e-05 22.4 0.5 5.3 5 0 0 5 5 5 3 Kelch motif Pkinase_Tyr PF07714.17 PRP76949.1 - 1.4e-14 54.1 0.1 2.5e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_2 PF07646.15 PRP76949.1 - 5.9e-12 45.1 3.7 0.0025 17.7 0.0 4.9 4 0 0 4 4 4 2 Kelch motif Pkinase PF00069.25 PRP76949.1 - 2.7e-07 30.2 0.0 5.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.6 PRP76949.1 - 6.7e-07 29.5 16.7 0.03 14.6 0.3 5.7 6 0 0 6 6 6 2 Galactose oxidase, central domain AAA_29 PF13555.6 PRP76949.1 - 0.005 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 PRP76949.1 - 0.0078 16.8 0.0 0.024 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP76949.1 - 0.0083 15.9 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 PRP76949.1 - 0.011 15.5 0.0 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_PrkA PF08298.11 PRP76949.1 - 0.044 12.7 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_24 PF13479.6 PRP76949.1 - 0.056 13.2 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PRP76949.1 - 0.084 13.4 0.0 0.24 11.9 0.0 1.7 2 0 0 2 2 1 0 ABC transporter RsgA_GTPase PF03193.16 PRP76949.1 - 0.091 12.7 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Sigma54_activat PF00158.26 PRP76949.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNase_P_pop3 PF08228.11 PRP76950.1 - 0.00067 19.7 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 RNase P subunit Pop3 FlaC_arch PF05377.11 PRP76950.1 - 0.086 13.3 0.2 0.086 13.3 0.2 5.2 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 PRP76950.1 - 0.38 11.2 0.0 0.38 11.2 0.0 6.6 4 1 2 6 6 6 0 Cell division protein ZapB Pentapeptide PF00805.22 PRP76951.1 - 6.9e-42 140.6 37.1 1.1e-13 50.6 4.9 4.4 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 PRP76951.1 - 2.6e-23 82.0 1.7 3.8e-12 46.2 0.0 2.5 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 PRP76951.1 - 6.3e-19 68.1 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 PRP76951.1 - 3.9e-18 65.3 0.3 3.7e-06 27.0 0.0 4.5 2 2 1 4 4 4 4 Pentapeptide repeats (9 copies) KHA PF11834.8 PRP76951.1 - 5.7e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel BTB PF00651.31 PRP76951.1 - 0.00014 22.1 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 PRP76951.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DNA_ligase_OB PF03120.16 PRP76951.1 - 0.027 14.3 0.4 22 5.0 0.0 3.7 2 2 1 3 3 3 0 NAD-dependent DNA ligase OB-fold domain TBP PF00352.21 PRP76954.1 - 0.055 13.4 0.2 1.4 8.9 0.1 2.3 1 1 1 2 2 2 0 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3586 PF12131.8 PRP76954.1 - 0.38 11.0 16.2 0.066 13.4 5.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3586) Furin-like_2 PF15913.5 PRP76954.1 - 0.71 10.1 9.1 1.4 9.1 0.4 2.7 1 1 1 3 3 3 0 Furin-like repeat, cysteine-rich RRM_1 PF00076.22 PRP76957.1 - 4.9e-26 90.4 0.5 2.4e-09 36.9 0.1 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP76957.1 - 5.8e-06 25.9 0.1 0.012 15.3 0.0 2.8 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PRP76957.1 - 8e-06 25.6 0.0 0.052 13.4 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 PRP76957.1 - 0.011 15.8 0.1 0.41 10.7 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif Inhibitor_I71 PF12628.7 PRP76957.1 - 0.12 12.2 2.0 0.25 11.2 2.0 1.5 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DUF755 PF05501.11 PRP76958.1 - 0.24 11.7 3.2 0.34 11.2 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TolA_bind_tri PF16331.5 PRP76958.1 - 2.2 8.4 9.9 19 5.4 6.0 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation TetM_leader PF08076.11 PRP76960.1 - 0.059 13.1 0.1 6.8 6.6 0.3 3.1 3 0 0 3 3 3 0 Tetracycline resistance determinant leader peptide bMG10 PF17973.1 PRP76962.1 - 1.1e-06 28.9 0.3 2.9e-06 27.5 0.3 1.7 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M PF00207.22 PRP76962.1 - 2.9e-06 27.0 0.0 7.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-2-macroglobulin family fn3 PF00041.21 PRP76962.1 - 0.06 13.7 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Fibronectin type III domain SPX PF03105.19 PRP76963.1 - 1.1e-30 107.9 5.6 2.9e-13 50.5 0.3 3.2 1 1 2 3 3 3 3 SPX domain Na_sulph_symp PF00939.19 PRP76963.1 - 3.2e-25 89.1 40.9 4.6e-25 88.6 40.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PRP76963.1 - 1.2e-20 74.0 49.4 7.5e-15 54.9 21.5 3.1 1 1 1 2 2 2 2 Citrate transporter DUF4850 PF16142.5 PRP76963.1 - 0.15 11.6 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) DUF1980 PF09323.10 PRP76963.1 - 0.52 10.2 3.8 20 5.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) TPR_19 PF14559.6 PRP76964.1 - 6.2e-05 23.4 0.4 0.45 11.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat CS PF04969.16 PRP76965.1 - 1.8e-08 35.3 0.0 2.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 CS domain Pkinase_Tyr PF07714.17 PRP76966.1 - 9.7e-48 162.7 0.0 3.1e-46 157.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP76966.1 - 2.3e-43 148.5 0.0 3.4e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP76966.1 - 9.1e-06 24.7 0.1 1.4e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 PRP76966.1 - 0.058 13.0 0.0 8.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PRP76966.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP76966.1 - 0.16 11.3 0.0 0.43 9.8 0.0 1.6 2 0 0 2 2 2 0 Kinase-like SH2 PF00017.24 PRP76967.1 - 2.7e-05 24.2 0.0 8.1e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DIOX_N PF14226.6 PRP76968.1 - 1.4e-26 93.5 0.1 2.5e-26 92.7 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PRP76968.1 - 1.1e-17 64.3 0.0 1.6e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 PRP76969.1 - 7.3e-14 52.1 0.0 1.5e-09 38.3 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP76969.1 - 3.6e-12 46.3 0.0 0.0011 19.2 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP76969.1 - 6.2e-10 38.5 0.0 0.1 13.2 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 PRP76969.1 - 1.3e-08 35.2 0.0 0.011 16.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP76969.1 - 4.8e-08 33.1 0.0 0.17 12.4 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat F-box-like PF12937.7 PRP76969.1 - 4.4e-06 26.5 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP76969.1 - 0.00047 20.0 0.6 0.0028 17.5 0.0 2.4 3 0 0 3 3 3 1 F-box domain RP-C_C PF11800.8 PRP76970.1 - 9 6.3 8.1 0.24 11.5 0.2 2.1 2 1 0 2 2 2 0 Replication protein C C-terminal region bMG10 PF17973.1 PRP76971.1 - 1.7e-32 112.3 0.8 1.1e-31 109.8 0.2 2.7 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M PF00207.22 PRP76971.1 - 9.5e-18 63.8 0.0 1.4e-16 60.1 0.0 2.9 2 0 0 2 2 2 1 Alpha-2-macroglobulin family A2M_BRD PF07703.14 PRP76971.1 - 1.1e-16 61.4 2.0 1.1e-16 61.4 2.0 3.8 4 1 0 4 4 4 1 Alpha-2-macroglobulin bait region domain MG2 PF01835.19 PRP76971.1 - 3e-16 59.6 0.1 1.1e-13 51.4 0.0 4.0 3 0 0 3 3 3 1 MG2 domain Big_5 PF13205.6 PRP76971.1 - 3.2e-05 24.6 6.6 0.26 12.0 0.1 6.1 5 1 1 6 6 6 1 Bacterial Ig-like domain TED_complement PF07678.14 PRP76971.1 - 3.7e-05 22.9 0.0 0.00038 19.6 0.0 2.1 2 0 0 2 2 2 1 A-macroglobulin TED domain DUF11 PF01345.18 PRP76971.1 - 0.00097 19.4 0.0 0.031 14.6 0.0 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF11 Filamin PF00630.19 PRP76971.1 - 0.3 11.9 6.4 16 6.3 0.0 4.6 4 0 0 4 4 4 0 Filamin/ABP280 repeat MG4 PF17789.1 PRP76971.1 - 0.97 9.6 6.3 9.3 6.5 0.0 5.0 6 0 0 6 6 6 0 Macroglobulin domain MG4 Big_1 PF02369.16 PRP76971.1 - 1.4 9.0 8.5 5.6 7.0 0.0 5.5 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 PRP76971.1 - 2.1 8.7 8.7 0.99 9.8 0.2 3.9 4 0 0 4 4 4 0 Invasin, domain 3 DPBB_1 PF03330.18 PRP76972.1 - 4.5e-06 26.8 0.2 3.6e-05 24.0 0.2 2.3 1 1 0 1 1 1 1 Lytic transglycolase KSHV_K1 PF11049.8 PRP76973.1 - 0.077 12.9 0.9 1.3 9.1 0.3 2.4 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus Inhibitor_I29 PF08246.12 PRP76974.1 - 3e-11 43.6 2.4 4.7e-11 42.9 2.4 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Propeptide_C1 PF08127.13 PRP76974.1 - 1.2e-07 31.5 0.5 2.4e-07 30.5 0.5 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Thionin PF00321.17 PRP76977.1 - 0.032 14.7 0.4 0.063 13.8 0.4 1.5 1 0 0 1 1 1 0 Plant thionin CAP59_mtransfer PF11735.8 PRP76978.1 - 3.4e-51 174.3 0.0 1.3e-50 172.3 0.0 1.9 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 HA PF03457.14 PRP76978.1 - 5.3e-18 65.1 0.4 1.4e-17 63.8 0.4 1.8 1 0 0 1 1 1 1 Helicase associated domain DEAD PF00270.29 PRP76978.1 - 9.4e-18 64.6 0.0 2.1e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP76978.1 - 1.3e-15 57.7 0.0 3.7e-14 53.0 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PRP76978.1 - 7.5e-11 42.6 3.2 8.2e-11 42.5 0.4 2.5 2 0 0 2 2 2 1 RecQ zinc-binding S1-like PF14444.6 PRP76978.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 S1-like Pro-kuma_activ PF09286.11 PRP76979.1 - 1.5e-31 109.6 2.2 3.4e-31 108.4 0.8 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP76979.1 - 0.00044 19.6 0.3 0.00044 19.6 0.3 1.8 2 0 0 2 2 2 1 Subtilase family DUF4832 PF16116.5 PRP76980.1 - 6e-06 26.3 0.0 2.2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4832) DUF4874 PF16173.5 PRP76980.1 - 0.0034 17.1 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) Ank_2 PF12796.7 PRP76981.1 - 7.8e-13 48.8 0.3 0.00015 22.3 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP76981.1 - 3.4e-08 33.9 0.0 0.00076 20.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP76981.1 - 7.7e-07 29.3 0.0 0.84 10.2 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat SPRY PF00622.28 PRP76981.1 - 1.2e-05 25.4 0.4 0.0058 16.7 0.1 3.2 3 0 0 3 3 3 1 SPRY domain Neuralized PF07177.12 PRP76981.1 - 1.9e-05 24.7 0.0 0.0025 17.8 0.1 2.8 2 1 0 2 2 2 1 Neuralized Ank_3 PF13606.6 PRP76981.1 - 8.8e-05 22.6 0.1 0.37 11.5 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat DUF2839 PF10999.8 PRP76981.1 - 0.00013 22.3 0.0 0.78 10.2 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2839) Glyco_hydro_31 PF01055.26 PRP76982.1 - 5.5e-141 470.7 2.4 6.9e-141 470.4 2.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 PRP76982.1 - 6e-30 103.8 0.5 1.4e-29 102.6 0.1 1.9 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 PRP76982.1 - 1.3e-15 57.4 2.3 2.4e-15 56.6 0.7 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF455 PF04305.14 PRP76983.1 - 8.3e-94 313.7 0.0 1.3e-93 313.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Kelch_1 PF01344.25 PRP76983.1 - 3e-36 122.7 8.8 2.6e-10 39.7 0.1 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PRP76983.1 - 7.8e-31 105.3 5.2 8.3e-08 32.2 0.1 6.3 2 1 4 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PRP76983.1 - 1.6e-21 76.0 2.0 0.00016 21.6 0.1 4.7 3 1 1 4 4 4 4 Galactose oxidase, central domain BTB_2 PF02214.22 PRP76983.1 - 4.8e-20 71.7 0.0 1.1e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 PRP76983.1 - 4.5e-15 54.9 2.8 0.00076 19.4 0.1 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 PRP76983.1 - 1e-08 35.2 11.3 0.0019 18.5 0.1 5.8 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP76983.1 - 1.6e-08 34.3 6.7 0.0066 16.4 0.3 5.5 5 0 0 5 5 5 3 Kelch motif Rieske PF00355.26 PRP76983.1 - 1.3e-07 31.5 0.1 3.1e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain BTB_3 PF16017.5 PRP76983.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DUF2633 PF11119.8 PRP76985.1 - 0.037 13.9 0.1 0.077 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) MM_CoA_mutase PF01642.22 PRP76991.1 - 4.9e-237 787.5 0.1 5.8e-237 787.3 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 PRP76991.1 - 2.5e-15 56.6 0.1 4.6e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 B12 binding domain TMEM154 PF15102.6 PRP76992.1 - 0.00031 20.7 0.0 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family Amnionless PF14828.6 PRP76992.1 - 0.00032 19.7 0.0 0.0081 15.0 0.0 2.8 3 0 0 3 3 3 1 Amnionless Cadherin_C_2 PF16492.5 PRP76992.1 - 0.0021 18.7 2.3 0.18 12.6 0.2 3.0 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal G8 PF10162.9 PRP76992.1 - 0.0092 16.0 0.9 0.0092 16.0 0.9 4.4 4 2 0 4 4 4 1 G8 domain Bactofilin PF04519.13 PRP76992.1 - 0.084 13.2 9.3 2.1 8.7 0.3 3.8 4 0 0 4 4 4 0 Polymer-forming cytoskeletal AIDA PF16168.5 PRP76992.1 - 0.14 12.3 7.7 0.45 10.6 3.9 3.4 2 1 1 3 3 3 0 Adhesin of bacterial autotransporter system, probable stalk Fcf2 PF08698.11 PRP76994.1 - 1.7e-17 63.6 0.6 1.7e-17 63.6 0.6 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing AAA_lid_6 PF17866.1 PRP76994.1 - 0.014 15.6 0.0 1.3 9.2 0.0 2.4 1 1 1 2 2 2 0 AAA lid domain Methyltransf_23 PF13489.6 PRP76995.1 - 2.1e-21 76.4 0.0 2.5e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP76995.1 - 9.3e-16 58.3 0.0 1.7e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP76995.1 - 1.1e-15 58.2 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP76995.1 - 1.7e-15 57.5 0.0 3.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP76995.1 - 1.8e-14 53.8 0.0 3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PRP76995.1 - 1.5e-07 30.6 0.0 2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 PRP76995.1 - 1.9e-07 30.6 0.0 2.4e-06 27.1 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 PRP76995.1 - 3.5e-05 23.5 0.0 4.7e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 PRP76995.1 - 0.00067 19.1 0.0 0.0013 18.2 0.0 1.5 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 PRP76995.1 - 0.0011 18.1 0.0 0.0014 17.7 0.0 1.3 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 PRP76995.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.12 PRP76995.1 - 0.0012 18.0 0.0 0.0022 17.1 0.0 1.4 2 0 0 2 2 2 1 DREV methyltransferase CMAS PF02353.20 PRP76995.1 - 0.0017 17.7 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 PRP76995.1 - 0.0017 18.3 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 PRP76995.1 - 0.0023 17.6 0.3 0.018 14.7 0.1 1.9 1 1 1 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 PRP76995.1 - 0.0035 16.9 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 PRP76995.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase tRNA_U5-meth_tr PF05958.11 PRP76995.1 - 0.06 12.3 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_16 PF10294.9 PRP76995.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase HECT PF00632.25 PRP76996.1 - 8.9e-53 179.8 0.0 1.5e-27 96.9 0.0 3.8 2 1 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Nramp PF01566.18 PRP76997.1 - 9.3e-52 176.2 8.3 9.3e-52 176.2 8.3 1.7 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein V-SNARE_C PF12352.8 PRP77000.1 - 2.5e-10 40.5 5.5 2.5e-10 40.5 5.5 2.9 3 1 1 4 4 4 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PRP77000.1 - 2.8e-06 27.2 1.4 4.7e-06 26.4 0.1 2.0 2 1 0 2 2 2 1 Sec20 V-SNARE PF05008.15 PRP77000.1 - 2.7e-05 24.4 1.0 2.7e-05 24.4 1.0 2.4 1 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Fusion_gly PF00523.18 PRP77000.1 - 0.00074 17.9 2.3 0.001 17.4 1.5 1.6 1 1 1 2 2 2 1 Fusion glycoprotein F0 RRF PF01765.19 PRP77000.1 - 0.035 14.1 0.3 0.074 13.0 0.3 1.5 1 0 0 1 1 1 0 Ribosome recycling factor Orf78 PF06024.12 PRP77000.1 - 0.06 13.7 1.4 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 Orf78 (ac78) FTA4 PF13093.6 PRP77000.1 - 1.3 8.9 7.9 3.4 7.5 7.9 1.7 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2207 PF09972.9 PRP77000.1 - 3.4 6.3 4.8 0.98 8.1 0.5 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) BK_channel_a PF03493.18 PRP77001.1 - 4.5e-17 62.0 0.0 2.1e-16 59.9 0.0 2.1 3 0 0 3 3 3 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 PRP77001.1 - 5.7e-15 55.2 15.8 3.1e-11 43.0 8.0 2.3 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 PRP77001.1 - 1.1e-12 47.7 3.5 1.1e-12 47.7 3.5 2.0 2 0 0 2 2 2 1 Ion channel Mpv17_PMP22 PF04117.12 PRP77002.1 - 2e-26 92.0 0.8 4.6e-26 90.8 0.8 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family TPR_1 PF00515.28 PRP77002.1 - 7.8e-09 35.0 6.3 0.00011 21.9 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP77002.1 - 2.3e-08 33.5 3.4 0.039 14.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP77002.1 - 0.001 19.1 1.1 0.3 11.4 0.6 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP77002.1 - 0.0029 18.3 0.2 3.1 8.8 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP77002.1 - 0.0031 17.5 0.5 0.012 15.7 0.2 2.1 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 PRP77002.1 - 0.0049 17.1 3.0 0.0091 16.2 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PRP77002.1 - 0.027 14.8 3.6 0.14 12.6 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP77002.1 - 0.043 13.5 0.6 0.55 10.0 0.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_19 PF14559.6 PRP77002.1 - 0.19 12.3 1.9 0.86 10.2 1.9 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP77002.1 - 0.32 11.7 1.9 13 6.5 0.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat UPF1_Zn_bind PF09416.10 PRP77003.1 - 5.5e-74 247.2 3.2 9.2e-74 246.5 2.5 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 PRP77003.1 - 5.7e-60 202.4 0.0 9.7e-60 201.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PRP77003.1 - 1.9e-51 175.4 2.7 2.5e-29 102.9 0.1 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 PRP77003.1 - 1.7e-33 114.7 0.0 3e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 PRP77003.1 - 2.6e-14 53.4 0.4 3.1e-13 49.9 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PRP77003.1 - 6.6e-11 42.7 0.1 3.3e-10 40.5 0.1 2.2 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 PRP77003.1 - 9.5e-06 25.7 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 PRP77003.1 - 1.2e-05 24.8 0.4 0.00018 20.9 0.1 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 PRP77003.1 - 2.1e-05 24.5 0.0 5.6e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 PRP77003.1 - 0.00013 21.8 0.3 0.14 11.9 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 PRP77003.1 - 0.00064 19.3 0.1 0.0085 15.6 0.0 2.6 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 PRP77003.1 - 0.00081 18.9 0.1 0.0016 18.0 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 PRP77003.1 - 0.0011 19.3 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 PRP77003.1 - 0.0012 18.7 0.2 0.0022 17.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATPase PF06745.13 PRP77003.1 - 0.0031 16.9 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 KaiC SRP54 PF00448.22 PRP77003.1 - 0.0084 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 PRP77003.1 - 0.0085 15.3 0.1 3 6.9 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase AAA_10 PF12846.7 PRP77003.1 - 0.04 12.8 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 PRP77003.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 PRP77003.1 - 0.069 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ribosomal_S13_N PF08069.12 PRP77003.1 - 0.092 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA PF00004.29 PRP77003.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 PRP77003.1 - 0.18 11.8 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Flavivirus DEAD domain C2 PF00168.30 PRP77004.1 - 5.7e-16 58.7 0.2 1.4e-15 57.4 0.2 1.7 1 0 0 1 1 1 1 C2 domain EB1 PF03271.17 PRP77004.1 - 1e-07 32.1 0.2 2.1e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif Methyltransf_16 PF10294.9 PRP77005.1 - 0.0001 22.1 0.1 0.00016 21.5 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase ABC2_membrane_6 PF06182.11 PRP77005.1 - 0.21 11.3 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein RT_RNaseH PF17917.1 PRP77006.1 - 1.6e-23 82.9 0.0 1.9e-22 79.5 0.0 2.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP77006.1 - 2.1e-22 79.0 0.0 1.2e-21 76.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 PRP77006.1 - 3e-15 56.4 0.0 6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 PRP77006.1 - 1.2e-08 34.9 0.0 3.8e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PRP77006.1 - 1.1e-07 32.0 0.1 4.9e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 H2C2 zinc finger Integrase_Zn PF02022.19 PRP77006.1 - 0.0028 17.6 0.9 0.0028 17.6 0.9 2.4 3 0 0 3 3 3 1 Integrase Zinc binding domain UBA PF00627.31 PRP77008.1 - 5.5e-07 29.4 0.2 0.14 12.1 0.0 4.4 4 0 0 4 4 4 2 UBA/TS-N domain Peptidase_C58 PF03543.14 PRP77008.1 - 0.0033 17.2 0.6 0.014 15.2 0.1 1.9 2 0 0 2 2 2 1 Yersinia/Haemophilus virulence surface antigen HBS1_N PF08938.10 PRP77008.1 - 0.12 12.7 1.6 5.1 7.5 0.0 3.1 3 0 0 3 3 3 0 HBS1 N-terminus DUF1296 PF06972.11 PRP77008.1 - 0.18 12.0 3.4 1.2 9.4 0.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1296) AAA PF00004.29 PRP77009.1 - 9.4e-25 87.6 0.0 6e-24 85.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP77009.1 - 1.7e-06 28.1 0.0 4.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 PRP77009.1 - 3.6e-06 27.0 0.5 1.2e-05 25.3 0.0 2.1 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain RuvB_N PF05496.12 PRP77009.1 - 3.5e-05 23.6 0.0 0.0006 19.6 0.0 2.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PRP77009.1 - 8.9e-05 22.7 0.0 0.00061 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 PRP77009.1 - 0.00012 21.1 0.0 0.00027 20.0 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 PRP77009.1 - 0.00014 22.1 0.3 0.034 14.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain Lon_C PF05362.13 PRP77009.1 - 0.0017 17.9 0.0 0.0051 16.4 0.0 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain MCM PF00493.23 PRP77009.1 - 0.004 16.3 0.0 0.01 14.9 0.0 1.7 1 1 0 1 1 1 1 MCM P-loop domain RsgA_GTPase PF03193.16 PRP77009.1 - 0.0048 16.8 0.0 0.047 13.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 PRP77009.1 - 0.0056 17.1 0.0 0.017 15.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 PRP77009.1 - 0.0074 16.0 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 PRP77009.1 - 0.008 16.6 0.2 0.034 14.5 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.6 PRP77009.1 - 0.0096 16.0 0.0 0.034 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PRP77009.1 - 0.02 15.4 0.0 0.055 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PRP77009.1 - 0.04 13.6 0.1 0.53 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 PRP77009.1 - 0.095 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase DUF3573 PF12097.8 PRP77009.1 - 0.096 11.5 0.6 0.2 10.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) AAA_7 PF12775.7 PRP77009.1 - 0.13 11.7 0.2 0.47 9.9 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_19 PF13245.6 PRP77009.1 - 0.2 12.0 0.6 7.9 6.8 0.0 3.2 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 PRP77009.1 - 0.41 11.2 4.5 0.65 10.5 0.0 3.4 4 0 0 4 4 4 0 ABC transporter NTPase_1 PF03266.15 PRP77009.1 - 0.52 10.2 3.2 17 5.3 0.1 2.9 2 1 1 3 3 3 0 NTPase G8 PF10162.9 PRP77010.1 - 1.3e-11 44.6 0.1 2.6e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 G8 domain CorA PF01544.18 PRP77010.1 - 6e-07 29.1 1.1 8.9e-07 28.5 1.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Bac_globin PF01152.21 PRP77010.1 - 0.012 15.7 0.1 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial-like globin RACo_C_ter PF14574.6 PRP77010.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of RACo the ASKHA domain DUF2105 PF09878.9 PRP77010.1 - 0.85 9.3 3.3 1.7 8.3 3.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) SET PF00856.28 PRP77011.1 - 1.1e-10 42.1 0.0 2.6e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 SET domain Yae1_N PF09811.9 PRP77012.1 - 3.2e-08 33.1 0.5 4.8e-08 32.6 0.5 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FAD-oxidase_C PF02913.19 PRP77013.1 - 2.1e-49 168.4 0.0 2.7e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PRP77013.1 - 1.8e-34 118.4 0.0 3.6e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PRP77013.1 - 0.052 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like GCV_T PF01571.21 PRP77014.1 - 2.1e-86 289.5 0.0 2.7e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 PRP77014.1 - 1.5e-18 66.5 0.1 2.9e-18 65.6 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 PRP77014.1 - 0.0014 18.8 0.1 0.088 13.0 0.0 2.2 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family DUF445 PF04286.12 PRP77015.1 - 0.011 15.5 0.2 0.012 15.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SmpA_OmlA PF04355.13 PRP77016.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 SmpA / OmlA family Transmemb_17 PF09799.9 PRP77017.1 - 4.6e-21 75.4 4.0 4.9e-11 43.2 1.5 2.2 2 0 0 2 2 2 2 Predicted membrane protein MFS_1 PF07690.16 PRP77018.1 - 3.3e-25 88.8 21.0 3.3e-25 88.8 21.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Pro_isomerase PF00160.21 PRP77019.1 - 6.2e-37 127.3 0.0 1.4e-36 126.2 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1279 PF06916.13 PRP77019.1 - 2.8e-08 34.2 0.1 7e-08 32.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SAP PF02037.27 PRP77019.1 - 1.8e-05 24.3 0.8 3.4e-05 23.5 0.8 1.4 1 0 0 1 1 1 1 SAP domain Cwf_Cwc_15 PF04889.12 PRP77019.1 - 0.1 12.3 3.8 0.16 11.7 3.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 PRP77019.1 - 7.3 4.6 9.3 12 3.8 9.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sec5 PF15469.6 PRP77020.1 - 1.8e-25 89.9 4.8 8.5e-24 84.4 4.8 2.6 1 1 0 1 1 1 1 Exocyst complex component Sec5 RINT1_TIP1 PF04437.13 PRP77020.1 - 0.00028 19.9 6.6 0.0024 16.8 0.4 3.2 3 0 0 3 3 3 1 RINT-1 / TIP-1 family Vps51 PF08700.11 PRP77020.1 - 0.068 13.2 1.2 0.47 10.6 0.0 3.0 3 0 0 3 3 3 0 Vps51/Vps67 DUF5344 PF17279.2 PRP77020.1 - 0.85 10.2 4.2 6.7 7.4 0.1 3.8 4 0 0 4 4 4 0 Family of unknown function (DUF5344) SAP PF02037.27 PRP77021.1 - 2.8e-09 36.5 2.0 3.5e-09 36.2 2.0 1.2 1 0 0 1 1 1 1 SAP domain ELH PF02323.15 PRP77021.1 - 0.019 14.4 1.9 0.021 14.2 1.9 1.0 1 0 0 1 1 1 0 Egg-laying hormone precursor DUF4763 PF15960.5 PRP77021.1 - 0.043 13.1 2.2 0.043 13.1 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) XRCC4 PF06632.12 PRP77021.1 - 0.073 11.9 3.3 0.077 11.8 3.3 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cwf_Cwc_15 PF04889.12 PRP77021.1 - 0.12 12.1 9.9 0.14 11.8 9.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 PRP77021.1 - 0.14 10.3 9.8 0.14 10.2 9.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi RCSD PF05177.12 PRP77023.1 - 3 8.8 12.0 33 5.5 12.0 2.2 1 1 0 1 1 1 0 RCSD region Endonuclea_NS_2 PF13930.6 PRP77024.1 - 0.0018 18.4 0.5 0.064 13.4 0.1 2.8 2 1 0 2 2 2 1 DNA/RNA non-specific endonuclease UTP15_C PF09384.10 PRP77028.1 - 0.027 14.1 0.1 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 UTP15 C terminal Drf_DAD PF06345.11 PRP77028.1 - 0.23 11.5 0.3 0.23 11.5 0.3 2.5 4 0 0 4 4 4 0 DRF Autoregulatory Domain LRR_6 PF13516.6 PRP77030.1 - 2.9e-45 148.5 51.9 1.7e-06 27.6 0.1 12.8 13 0 0 13 13 13 9 Leucine Rich repeat LRR_1 PF00560.33 PRP77030.1 - 9.9e-09 34.6 0.0 29 5.7 0.0 7.4 8 0 0 8 8 7 0 Leucine Rich Repeat LRR_4 PF12799.7 PRP77030.1 - 1.3e-08 35.0 30.2 0.018 15.4 0.6 7.3 3 3 6 9 9 9 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PRP77030.1 - 0.00036 20.4 0.1 0.00092 19.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PRP77030.1 - 0.0013 18.4 34.2 0.1 12.4 1.4 7.2 4 2 3 7 7 7 2 Leucine rich repeat F-box PF00646.33 PRP77030.1 - 0.028 14.3 1.0 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 F-box domain PH_5 PF15405.6 PRP77030.1 - 0.03 14.4 3.1 1.5 9.0 0.0 2.6 1 1 1 2 2 2 0 Pleckstrin homology domain Act-Frag_cataly PF09192.10 PRP77030.1 - 0.049 13.0 0.5 0.087 12.2 0.5 1.3 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Apo-CII PF05355.11 PRP77030.1 - 0.087 13.0 12.9 9 6.5 0.1 6.0 3 2 3 8 8 8 0 Apolipoprotein C-II MIase PF02426.16 PRP77030.1 - 0.18 12.0 0.7 0.71 10.1 0.1 2.2 1 1 1 2 2 2 0 Muconolactone delta-isomerase DUF3701 PF12482.8 PRP77030.1 - 0.34 11.0 10.1 31 4.7 0.1 6.6 6 2 3 9 9 8 0 Phage integrase protein SPOUT_MTase PF02590.17 PRP77030.1 - 0.44 10.5 4.1 6.9 6.6 0.1 3.3 1 1 2 3 3 3 0 Predicted SPOUT methyltransferase FumaraseC_C PF10415.9 PRP77030.1 - 1.1 9.8 22.4 2.9 8.4 0.2 7.2 4 1 5 9 9 8 0 Fumarase C C-terminus Fucose_iso_C PF02952.17 PRP77030.1 - 1.1 8.9 5.1 36 4.0 0.0 3.7 2 1 0 3 3 3 0 L-fucose isomerase, C-terminal domain Pkinase_Tyr PF07714.17 PRP77032.1 - 6e-05 22.5 0.0 9.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1192 PF06698.11 PRP77032.1 - 0.052 13.6 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) rve PF00665.26 PRP77032.1 - 0.078 13.2 0.0 0.26 11.5 0.0 1.9 1 1 0 1 1 1 0 Integrase core domain CK2S PF15011.6 PRP77032.1 - 0.14 12.1 0.7 0.5 10.2 0.1 2.2 2 1 1 3 3 3 0 Casein Kinase 2 substrate PerC PF06069.11 PRP77034.1 - 0.69 10.2 5.5 0.68 10.2 2.2 2.6 2 0 0 2 2 2 0 PerC transcriptional activator DUF4778 PF16008.5 PRP77035.1 - 0.014 15.5 0.1 0.016 15.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF4533 PF15047.6 PRP77035.1 - 0.031 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) SAM_2 PF07647.17 PRP77036.1 - 0.00066 19.7 0.6 0.0016 18.5 0.0 1.9 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP77036.1 - 0.0014 19.0 0.0 0.0028 18.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1216 PF06746.11 PRP77037.1 - 0.025 14.6 0.1 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) DUF1192 PF06698.11 PRP77039.1 - 0.13 12.3 0.4 0.24 11.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MM_CoA_mutase PF01642.22 PRP77041.1 - 0.015 13.9 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase MM_CoA_mutase PF01642.22 PRP77042.1 - 2.1e-21 76.1 0.4 2.5e-13 49.4 0.0 3.0 1 1 2 3 3 3 3 Methylmalonyl-CoA mutase Lipoprotein_X PF03305.13 PRP77042.1 - 0.22 11.3 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein WD40 PF00400.32 PRP77043.1 - 8.2e-11 42.3 4.1 4.7e-06 27.2 0.0 5.6 4 2 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP77043.1 - 0.0042 17.3 0.1 3.3 8.1 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain LRR_8 PF13855.6 PRP77044.1 - 7.6e-37 124.9 69.2 2.2e-10 40.1 0.1 10.1 9 2 1 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 PRP77044.1 - 2.7e-36 123.0 66.8 1.5e-05 25.2 0.2 13.8 10 3 5 16 16 16 13 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP77044.1 - 3e-13 48.7 57.1 1.1 9.5 0.0 18.2 20 0 0 20 20 20 9 Leucine Rich repeat LRR_1 PF00560.33 PRP77044.1 - 7.9e-05 22.7 60.7 0.14 12.8 0.1 16.3 20 3 1 21 21 21 6 Leucine Rich Repeat DUF962 PF06127.11 PRP77046.1 - 2.9e-06 27.3 1.5 1.1e-05 25.4 1.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) YjeF_N PF03853.15 PRP77047.1 - 3.8e-34 118.0 0.1 5.5e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 PRP77047.1 - 4.1e-06 27.6 0.6 4.1e-06 27.6 0.6 2.3 2 0 0 2 2 2 1 FDF domain Arb2 PF09757.9 PRP77047.1 - 0.0051 16.0 0.0 0.21 10.7 0.0 2.4 2 0 0 2 2 2 1 Arb2 domain THF_DHG_CYH_C PF02882.19 PRP77047.1 - 0.087 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LSM PF01423.22 PRP77047.1 - 0.15 11.7 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 LSM domain Pkinase PF00069.25 PRP77048.1 - 5.2e-45 153.9 0.0 6.8e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77048.1 - 1e-20 74.1 0.0 1.4e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP77048.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP77048.1 - 0.0076 15.1 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 PRP77049.1 - 3e-05 23.7 0.0 9.6e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBFD_NFYB_HMF PF00808.23 PRP77049.1 - 5.9 7.2 7.2 5.2 7.4 1.9 3.1 2 1 1 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C3HC4_3 PF13920.6 PRP77050.1 - 9e-16 57.5 12.4 1.6e-15 56.7 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP77050.1 - 8e-08 32.0 11.9 1.6e-07 31.1 11.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PRP77050.1 - 1e-06 28.9 12.4 2.2e-06 27.9 12.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PRP77050.1 - 4.1e-05 23.4 12.7 4.1e-05 23.4 12.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP77050.1 - 0.00041 20.2 11.0 0.00091 19.1 11.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PRP77050.1 - 0.0019 18.0 12.2 0.004 17.0 12.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PRP77050.1 - 0.035 13.9 9.5 0.072 12.9 9.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cupredoxin_1 PF13473.6 PRP77050.1 - 0.13 12.4 0.2 0.25 11.5 0.2 1.5 1 0 0 1 1 1 0 Cupredoxin-like domain zf-P11 PF03854.14 PRP77050.1 - 0.18 11.5 8.3 0.26 11.0 7.3 1.7 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_11 PF17123.5 PRP77050.1 - 2.7 7.8 8.6 0.78 9.5 0.7 2.9 3 0 0 3 3 3 0 RING-like zinc finger PHF5 PF03660.14 PRP77050.1 - 3 8.1 9.8 0.55 10.5 1.5 2.6 1 1 1 2 2 2 0 PHF5-like protein zf-RING_UBOX PF13445.6 PRP77050.1 - 3.7 7.7 9.8 0.46 10.6 3.5 2.6 2 1 1 3 3 3 0 RING-type zinc-finger Y_phosphatase PF00102.27 PRP77053.1 - 2.5e-77 259.6 0.1 3.1e-77 259.3 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PRP77053.1 - 7.3e-09 35.5 0.0 1.5e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PRP77053.1 - 0.0019 18.2 0.0 0.0055 16.7 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PRP77053.1 - 0.0095 16.1 0.1 0.044 13.9 0.1 2.2 1 1 1 2 2 2 1 Inositol hexakisphosphate Malic_M PF03949.15 PRP77054.1 - 8.8e-101 336.5 0.1 1.3e-100 335.9 0.1 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 PRP77054.1 - 4.4e-73 245.0 0.0 7e-73 244.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Glyco_hydro_35 PF01301.19 PRP77055.1 - 2.2e-103 346.2 0.0 2.8e-103 345.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 PRP77055.1 - 4.5e-11 42.7 0.0 3.4e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 PRP77055.1 - 0.00015 21.3 0.0 0.00046 19.7 0.0 1.8 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BetaGal_dom4_5 PF13364.6 PRP77055.1 - 0.0003 21.3 5.3 0.0013 19.3 0.5 3.1 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain DUF3592 PF12158.8 PRP77055.1 - 0.061 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) p450 PF00067.22 PRP77056.1 - 1.5e-109 366.8 0.1 5.3e-57 193.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome P450 MWFE PF15879.5 PRP77056.1 - 0.0066 16.6 1.8 0.65 10.2 0.1 3.3 3 0 0 3 3 3 2 NADH-ubiquinone oxidoreductase MWFE subunit Pkinase_Tyr PF07714.17 PRP77057.1 - 1.1e-50 172.4 0.0 1.5e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77057.1 - 1e-33 116.9 0.0 1.8e-33 116.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP77057.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP77057.1 - 0.003 16.9 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP77057.1 - 0.058 12.2 0.3 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase DUF2333 PF10095.9 PRP77057.1 - 0.15 11.1 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) Cellulase PF00150.18 PRP77058.1 - 2.7e-17 63.1 4.6 3.7e-17 62.7 4.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pantoate_transf PF02548.15 PRP77059.1 - 1e-110 369.2 1.0 1.8e-110 368.4 1.0 1.4 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 PRP77059.1 - 9.2e-34 116.3 0.3 4.6e-33 114.1 0.3 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 PRP77059.1 - 3.8e-27 94.8 0.6 8e-27 93.7 0.6 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PEP_mutase PF13714.6 PRP77059.1 - 1.9e-05 24.3 0.4 1.9e-05 24.3 0.4 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 PRP77059.1 - 0.0017 18.3 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF4394 PF14339.6 PRP77059.1 - 0.0047 16.3 0.1 0.0089 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4394) DUF3818 PF12825.7 PRP77060.1 - 9.9e-99 330.6 0.0 1.7e-98 329.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 PRP77060.1 - 8.2e-35 119.6 0.1 1.7e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 PRP77060.1 - 1.7e-09 37.6 0.1 5.4e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 PX domain Lactonase PF10282.9 PRP77061.1 - 1e-70 238.7 0.0 1.2e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PAN_4 PF14295.6 PRP77061.1 - 1.2e-10 41.2 6.7 4e-10 39.4 6.7 2.0 1 0 0 1 1 1 1 PAN domain LVIVD PF08309.11 PRP77061.1 - 0.001 18.4 2.8 0.7 9.3 0.0 3.7 3 0 0 3 3 3 1 LVIVD repeat PAN_2 PF08276.11 PRP77061.1 - 0.0058 16.7 5.5 0.015 15.4 5.5 1.7 1 0 0 1 1 1 1 PAN-like domain DUF5074 PF16819.5 PRP77061.1 - 0.085 12.9 0.1 1.1 9.3 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5074) DUF4643 PF15485.6 PRP77064.1 - 0.059 13.2 0.3 0.071 12.9 0.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4643) Pkinase PF00069.25 PRP77065.1 - 2.2e-66 223.9 0.0 2.6e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77065.1 - 1.6e-39 135.8 0.0 2e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP77065.1 - 4e-06 26.3 0.2 4e-06 26.3 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP77065.1 - 6.5e-05 23.0 0.0 0.072 13.0 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP77065.1 - 0.00065 18.7 0.1 0.00087 18.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PRP77065.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.5 1 1 1 2 2 2 1 Kinase-like DUF1922 PF09082.10 PRP77065.1 - 0.018 15.3 0.0 0.059 13.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) DUF5385 PF17359.2 PRP77065.1 - 0.057 13.0 0.1 0.085 12.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Abhydrolase_1 PF00561.20 PRP77066.1 - 6.2e-17 62.1 0.2 4.7e-13 49.4 0.0 2.3 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP77066.1 - 1.2e-12 47.6 0.0 2.7e-08 33.4 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP77066.1 - 2.9e-08 34.6 0.0 5.2e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 PRP77066.1 - 2.8e-05 23.0 0.0 4.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 PRP77066.1 - 0.0042 16.5 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 PRP77066.1 - 0.0095 15.4 0.0 0.24 10.8 0.0 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Palm_thioest PF02089.15 PRP77066.1 - 0.0098 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF1057 PF06342.12 PRP77066.1 - 0.02 13.9 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydro_lipase PF04083.16 PRP77066.1 - 0.066 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF1325 PF07039.11 PRP77067.1 - 4.5e-34 117.4 0.3 7.3e-34 116.7 0.3 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 PRP77067.1 - 2.6e-05 24.0 0.1 7.9e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 PRP77067.1 - 4.2e-05 23.9 0.2 0.25 11.8 0.0 2.5 2 0 0 2 2 2 2 Agenet domain LBR_tudor PF09465.10 PRP77067.1 - 0.00035 20.3 0.1 0.58 10.0 0.0 2.3 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 PRP77067.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Sm_multidrug_ex PF06695.11 PRP77069.1 - 0.0096 16.6 1.0 0.013 16.2 0.5 1.4 1 1 0 1 1 1 1 Putative small multi-drug export protein XRN_N PF03159.18 PRP77070.1 - 0.00089 18.8 0.0 0.00098 18.6 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PRP77071.1 - 1.7e-20 73.4 3.7 1e-19 70.8 0.4 2.4 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 PRP77071.1 - 5.3e-05 22.8 0.0 0.00013 21.5 0.0 1.8 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Toxin_34 PF08396.10 PRP77072.1 - 0.03 15.1 0.4 0.081 13.7 0.1 1.8 2 0 0 2 2 2 0 Spider toxin omega agatoxin/Tx1 family Peptidase_C48 PF02902.19 PRP77075.1 - 1.8e-08 34.5 0.0 1.1e-07 31.9 0.0 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RSS_P20 PF11757.8 PRP77077.1 - 0.0076 16.7 2.0 0.98 9.9 1.4 2.8 2 1 0 2 2 2 1 Suppressor of RNA silencing P21-like N-terminal domain DUF3450 PF11932.8 PRP77077.1 - 0.046 13.0 3.7 0.067 12.5 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF5582 PF17819.1 PRP77077.1 - 0.23 11.9 3.6 0.34 11.3 3.6 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5582) Seryl_tRNA_N PF02403.22 PRP77077.1 - 0.47 10.7 4.1 0.6 10.4 2.4 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 PRP77079.1 - 2.5e-24 86.1 0.1 5.7e-19 68.5 0.0 2.5 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77079.1 - 6.8e-13 48.5 0.0 4.3e-11 42.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PRP77079.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4287 PF14117.6 PRP77080.1 - 0.0055 16.8 0.1 7.1 6.9 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4287) Tim29 PF10171.9 PRP77080.1 - 0.079 12.5 0.1 1.9 7.9 0.0 2.4 1 1 1 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 REV PF00424.18 PRP77080.1 - 0.092 12.8 3.8 3.2 7.8 1.3 3.3 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) RIB43A PF05914.12 PRP77080.1 - 0.15 10.8 4.9 0.044 12.5 2.1 1.5 2 0 0 2 2 2 0 RIB43A PI_PP_C PF18365.1 PRP77087.1 - 0.14 12.2 0.1 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain HATPase_c PF02518.26 PRP77092.1 - 3.6e-25 88.6 1.1 4.4e-25 88.4 0.2 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP77092.1 - 1.4e-21 76.7 4.6 1.8e-19 69.9 0.3 2.8 3 0 0 3 3 3 2 Response regulator receiver domain BRCT_3 PF18428.1 PRP77092.1 - 0.0014 18.7 0.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HATPase_c_3 PF13589.6 PRP77092.1 - 0.0042 16.9 0.0 0.0074 16.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec1 PF00995.23 PRP77092.1 - 0.036 13.3 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Sec1 family NMD3 PF04981.13 PRP77094.1 - 4.2e-81 272.0 8.0 5.4e-81 271.6 8.0 1.1 1 0 0 1 1 1 1 NMD3 family Ago_PAZ PF18309.1 PRP77094.1 - 0.042 14.5 0.1 0.11 13.1 0.1 1.7 1 0 0 1 1 1 0 Argonaute PAZ domain HypA PF01155.19 PRP77094.1 - 0.075 13.1 7.6 0.46 10.5 3.8 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 PRP77094.1 - 2.3 8.3 15.0 14 5.8 8.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon DUF1289 PF06945.13 PRP77094.1 - 4.6 7.1 8.1 2.7 7.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) Maf PF02545.14 PRP77095.1 - 1.6e-28 99.6 0.0 1.8e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein zf_C2H2_10 PF18414.1 PRP77095.1 - 0.1 12.2 0.2 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger UQ_con PF00179.26 PRP77096.1 - 3.8e-42 143.3 0.0 5.1e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PRP77096.1 - 0.00036 20.4 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PRP77096.1 - 0.00076 19.8 0.1 0.002 18.4 0.1 1.4 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.11 PRP77096.1 - 0.082 12.5 0.0 0.32 10.6 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 ELO PF01151.18 PRP77097.1 - 3.4e-62 210.2 18.7 4e-62 210.0 18.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ank_2 PF12796.7 PRP77098.1 - 4e-24 85.0 0.0 2.3e-08 34.5 0.0 4.7 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP77098.1 - 1.7e-11 43.2 2.1 0.045 14.3 0.0 7.5 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 PRP77098.1 - 5.4e-11 42.4 9.6 0.014 15.8 0.1 6.9 5 2 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PRP77098.1 - 2.7e-09 37.1 4.3 0.0037 17.5 0.0 7.1 5 2 3 8 8 8 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP77098.1 - 3.3e-09 37.1 0.3 1.6 9.4 0.0 5.5 4 3 1 5 5 5 3 Ankyrin repeats (many copies) WWE PF02825.20 PRP77099.1 - 1.9e-08 34.8 1.5 1.9e-08 34.8 1.5 1.9 2 0 0 2 2 2 1 WWE domain NYN PF01936.18 PRP77099.1 - 9.5e-08 32.6 0.0 2.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 NYN domain RRM_1 PF00076.22 PRP77099.1 - 9.5e-05 22.1 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP77099.1 - 0.0069 16.5 0.0 0.022 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif DUF5615 PF18480.1 PRP77099.1 - 0.1 12.4 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) zf-C2H2 PF00096.26 PRP77099.1 - 0.47 11.0 1.9 0.88 10.2 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase_Tyr PF07714.17 PRP77100.1 - 1.1e-65 221.5 0.0 1.6e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77100.1 - 4.3e-46 157.4 0.0 7.3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Rap_GAP PF02145.15 PRP77100.1 - 1e-42 145.8 0.0 2e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP LRR_8 PF13855.6 PRP77100.1 - 4e-38 129.0 68.3 1.2e-05 25.0 0.9 13.8 10 3 4 15 15 15 11 Leucine rich repeat LRR_4 PF12799.7 PRP77100.1 - 4.8e-29 99.9 69.4 7.1e-05 23.1 4.5 17.3 16 2 1 17 17 17 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP77100.1 - 6.3e-06 26.0 48.0 0.59 10.9 0.9 17.0 19 2 0 19 19 19 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP77100.1 - 0.00034 20.4 40.3 23 5.4 0.2 15.5 19 0 0 19 19 19 0 Leucine Rich repeat Adeno_E3_CR2 PF02439.15 PRP77100.1 - 0.022 14.5 1.5 0.056 13.2 1.5 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 PRP77100.1 - 0.87 9.1 3.0 2 7.9 3.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase PF00069.25 PRP77101.1 - 1.1e-58 198.7 0.0 2.2e-58 197.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77101.1 - 1.4e-36 126.1 0.0 2.6e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase WW PF00397.26 PRP77101.1 - 1.6e-08 34.5 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 WW domain Kinase-like PF14531.6 PRP77101.1 - 4.6e-05 22.9 0.0 0.00013 21.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like UPF0730 PF15827.5 PRP77102.1 - 0.018 14.7 0.2 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 UPF0730 unknown protein family SET PF00856.28 PRP77104.1 - 0.0005 20.5 0.3 0.0013 19.2 0.1 1.7 2 0 0 2 2 2 1 SET domain CSD PF00313.22 PRP77104.1 - 0.013 15.4 0.0 1.5 8.7 0.0 2.7 2 1 0 2 2 2 0 'Cold-shock' DNA-binding domain Actin PF00022.19 PRP77105.1 - 1.4e-20 73.3 0.1 1.5e-20 73.2 0.1 1.0 1 0 0 1 1 1 1 Actin Lipase_3 PF01764.25 PRP77106.1 - 2.9e-13 49.9 0.0 6.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) fn3 PF00041.21 PRP77106.1 - 4.4e-11 43.0 1.5 1.4e-10 41.3 1.5 2.0 1 0 0 1 1 1 1 Fibronectin type III domain Hamartin PF04388.12 PRP77106.1 - 5.2 5.6 19.8 8.4 4.9 19.8 1.3 1 0 0 1 1 1 0 Hamartin protein DUF3042 PF11240.8 PRP77107.1 - 5.9 7.0 5.9 29 4.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) Josephin PF02099.17 PRP77108.1 - 2.4e-48 164.3 0.0 4.2e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Josephin UBX PF00789.20 PRP77108.1 - 8.5e-15 54.7 0.0 1.9e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain Phytoreo_P8 PF07124.11 PRP77108.1 - 0.094 11.7 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Snf7 PF03357.21 PRP77109.1 - 1.8e-31 109.0 27.1 2.2e-31 108.7 27.1 1.1 1 0 0 1 1 1 1 Snf7 DUF2726 PF10881.8 PRP77109.1 - 0.021 14.7 1.7 0.037 13.9 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) Kri1 PF05178.12 PRP77109.1 - 0.16 12.5 12.0 0.074 13.6 8.0 2.3 1 1 1 2 2 2 0 KRI1-like family PhoLip_ATPase_C PF16212.5 PRP77110.1 - 1e-85 287.5 25.1 1e-85 287.5 25.1 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP77110.1 - 1.3e-18 66.4 0.5 1.3e-18 66.4 0.5 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 PRP77110.1 - 7.6e-14 51.6 0.1 7.6e-14 51.6 0.1 3.3 3 1 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PRP77110.1 - 4.8e-11 43.3 8.2 1.2e-05 25.7 4.9 3.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PRP77110.1 - 2e-09 37.2 1.2 9.5e-09 35.0 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PRP77110.1 - 0.00035 20.4 1.2 0.00035 20.4 1.2 3.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PASTA PF03793.19 PRP77110.1 - 0.047 13.6 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 PASTA domain DUF4976 PF16347.5 PRP77110.1 - 0.41 10.9 2.7 1.8 8.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4976) F-box PF00646.33 PRP77111.1 - 5.2e-06 26.2 0.3 0.00013 21.8 0.1 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP77111.1 - 0.013 15.4 1.4 0.028 14.3 0.1 2.2 2 0 0 2 2 2 0 F-box-like HTH_10 PF04967.12 PRP77111.1 - 0.019 14.8 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 0 HTH DNA binding domain Ank_4 PF13637.6 PRP77111.1 - 0.077 13.6 0.1 3.6 8.3 0.0 3.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF1924 PF09086.11 PRP77111.1 - 0.19 12.1 0.7 2.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) LCAT PF02450.15 PRP77113.1 - 3.9e-06 26.3 0.0 5.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 PRP77113.1 - 0.00017 22.3 0.1 0.00033 21.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 PRP77113.1 - 0.00041 20.5 0.0 0.00083 19.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 PRP77113.1 - 0.00071 19.4 0.0 0.0069 16.1 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 PRP77113.1 - 0.0019 17.5 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PRP77113.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PRP77113.1 - 0.033 13.8 0.1 0.082 12.5 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 PRP77113.1 - 0.04 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Abhydrolase_8 PF06259.12 PRP77113.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase FSH1 PF03959.13 PRP77115.1 - 8.2e-50 169.4 0.0 1.2e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 PRP77115.1 - 0.024 14.3 0.0 3.9 7.0 0.0 2.3 1 1 0 2 2 2 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 PRP77116.1 - 7e-85 284.7 0.0 8.1e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 PRP77116.1 - 8e-05 22.4 0.0 0.00014 21.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 PRP77116.1 - 0.022 14.1 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 PRP77116.1 - 0.057 12.9 0.0 0.35 10.4 0.0 2.1 2 1 0 2 2 2 0 Lipase (class 2) HECW_N PF16562.5 PRP77116.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 zf-Di19 PF05605.12 PRP77119.1 - 1.3e-06 28.6 13.2 0.0021 18.3 0.4 3.8 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 PRP77119.1 - 7e-05 22.6 6.6 7e-05 22.6 6.6 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_4 PF13894.6 PRP77119.1 - 0.11 13.3 0.2 0.11 13.3 0.2 7.3 7 2 1 8 8 8 0 C2H2-type zinc finger FAD_binding_3 PF01494.19 PRP77120.1 - 1.5e-14 54.1 0.0 2e-07 30.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 PRP77120.1 - 0.00069 19.8 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP77120.1 - 0.047 13.3 0.1 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PRP77120.1 - 0.053 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 PRP77120.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PRP77120.1 - 0.24 10.6 0.0 0.43 9.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP77120.1 - 0.27 10.5 0.2 1 8.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_16 PF13191.6 PRP77121.1 - 3.8e-39 134.8 0.3 1.3e-38 133.0 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain HATPase_c PF02518.26 PRP77121.1 - 5.7e-25 88.0 0.3 1.8e-24 86.4 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP77121.1 - 3.6e-23 81.9 0.8 1.2e-22 80.2 0.8 2.0 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.25 PRP77121.1 - 4.2e-20 72.2 0.6 9.5e-20 71.1 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77121.1 - 4e-10 39.4 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF5009 PF16401.5 PRP77121.1 - 1.9e-08 34.1 13.0 6.4e-08 32.4 8.2 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF5009) GAF PF01590.26 PRP77121.1 - 9.1e-06 26.3 0.0 2.5e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 PRP77121.1 - 1.1e-05 25.4 0.2 0.0001 22.3 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP77121.1 - 0.00025 20.9 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 PRP77121.1 - 0.00047 20.5 0.0 0.0015 18.8 0.0 2.0 2 0 0 2 2 1 1 GAF domain Kinase-like PF14531.6 PRP77121.1 - 0.0012 18.2 0.3 0.0049 16.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like AAA_22 PF13401.6 PRP77121.1 - 0.0017 18.6 0.0 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PRP77121.1 - 0.0088 15.8 1.6 2.5 7.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain DUF4363 PF14276.6 PRP77121.1 - 0.056 13.6 4.5 1.2 9.3 0.9 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Actin PF00022.19 PRP77122.1 - 6.9e-145 482.7 0.0 2.2e-144 481.1 0.0 1.6 1 1 0 1 1 1 1 Actin DUF5381 PF17353.2 PRP77125.1 - 2.5 7.8 9.6 2 8.2 0.2 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5381) PPR PF01535.20 PRP77126.1 - 0.0073 16.5 0.1 7.7 7.0 0.0 3.2 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 PRP77126.1 - 0.075 13.2 0.1 3 8.1 0.0 2.8 1 1 1 2 2 2 0 PPR repeat family zf-met2 PF12907.7 PRP77127.1 - 1.9e-18 66.3 3.6 2.6e-18 65.8 3.6 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 PRP77127.1 - 0.00042 21.1 4.5 0.00042 21.1 4.5 1.9 2 0 0 2 2 2 1 4F5 protein family zf-BED PF02892.15 PRP77127.1 - 0.086 12.9 0.5 0.13 12.3 0.5 1.3 1 0 0 1 1 1 0 BED zinc finger AAA_16 PF13191.6 PRP77128.1 - 6.9e-35 120.9 0.0 2.2e-34 119.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Response_reg PF00072.24 PRP77128.1 - 2.1e-20 73.0 0.1 6.4e-20 71.4 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.25 PRP77128.1 - 1.1e-19 70.8 0.0 4.1e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain HATPase_c PF02518.26 PRP77128.1 - 1.1e-18 67.7 0.0 4.1e-18 65.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 PRP77128.1 - 1.4e-09 38.7 0.0 3.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 PRP77128.1 - 1.6e-07 31.2 0.0 8.2e-07 29.0 0.0 2.3 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 PRP77128.1 - 2.2e-07 31.3 0.0 1.7e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 PRP77128.1 - 0.0016 18.3 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sigma54_activat PF00158.26 PRP77128.1 - 0.053 13.2 0.0 2.7 7.7 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_pol_Rpb2_6 PF00562.28 PRP77129.1 - 2.6e-125 418.6 0.2 3.9e-125 418.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PRP77129.1 - 4.1e-52 176.7 0.3 6.2e-52 176.1 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 PRP77129.1 - 6.4e-33 113.0 0.1 1.5e-32 111.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 PRP77129.1 - 2.6e-25 88.5 0.3 6.8e-25 87.1 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 PRP77129.1 - 3.5e-25 88.7 2.0 7.4e-25 87.7 2.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 PRP77129.1 - 5.5e-21 74.5 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 PRP77129.1 - 5.8e-13 49.2 0.1 2.2e-12 47.3 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SNF2_N PF00176.23 PRP77131.1 - 1.9e-66 224.2 0.0 4.3e-66 223.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP77131.1 - 4e-20 72.2 0.0 1e-18 67.7 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP77131.1 - 3.8e-07 30.3 0.1 2e-05 24.6 0.0 3.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PRP77131.1 - 2e-06 27.2 5.2 4.2e-05 22.9 0.0 3.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 PRP77131.1 - 0.062 12.5 0.1 0.062 12.5 0.1 2.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAR2 PF05282.11 PRP77131.1 - 0.36 10.2 8.3 0.92 8.8 8.3 1.7 1 0 0 1 1 1 0 AAR2 protein EIIBC-GUT_N PF03612.14 PRP77131.1 - 2.9 7.6 7.5 9 6.0 7.5 1.8 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GpcrRhopsn4 PF10192.9 PRP77132.1 - 8.4e-55 186.0 14.9 1.3e-54 185.4 14.9 1.3 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Serinc PF03348.15 PRP77133.1 - 4.9e-113 378.3 13.6 5.8e-113 378.1 13.6 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Deltameth_res PF16020.5 PRP77133.1 - 0.011 15.6 1.4 0.035 14.0 0.0 2.7 2 0 0 2 2 2 0 Deltamethrin resistance DUF2516 PF10724.9 PRP77133.1 - 0.014 15.7 0.8 0.014 15.7 0.8 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF2516) UPF0239 PF06783.11 PRP77133.1 - 0.081 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF5316 PF17247.2 PRP77133.1 - 6.1 6.9 0.0 6.1 6.9 0.0 4.6 6 0 0 6 6 6 0 Family of unknown function (DUF5316) CoA_transf_3 PF02515.17 PRP77136.1 - 1.3e-126 422.6 0.0 1.7e-126 422.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Trypsin_2 PF13365.6 PRP77137.1 - 0.0037 18.2 0.0 0.0065 17.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Biliv-reduc_cat PF09166.10 PRP77139.1 - 0.039 14.3 0.0 0.041 14.2 0.0 1.1 1 0 0 1 1 1 0 Biliverdin reductase, catalytic Glyco_transf_5 PF08323.11 PRP77143.1 - 7.7e-40 137.1 0.0 1.5e-39 136.2 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 PRP77143.1 - 4.9e-12 45.7 0.0 4.6e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PRP77143.1 - 3.1e-09 37.4 0.0 9.4e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.24 PRP77143.1 - 2.5e-05 24.0 0.0 0.0019 17.8 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_transf_4 PF13439.6 PRP77143.1 - 0.00027 21.0 0.2 0.00062 19.8 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PRP77143.1 - 0.00087 19.8 0.0 0.0025 18.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Alpha-amylase_C PF02806.18 PRP77143.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain ubiquitin PF00240.23 PRP77144.1 - 4.2e-05 23.2 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family C_GCAxxG_C_C PF09719.10 PRP77144.1 - 0.05 13.9 4.0 0.068 13.5 4.0 1.2 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) LRR_8 PF13855.6 PRP77145.1 - 1.4e-53 178.5 56.6 6.8e-10 38.6 5.2 8.9 6 3 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 PRP77145.1 - 8.8e-43 143.6 62.4 3.3e-08 33.7 2.6 12.3 7 3 3 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP77145.1 - 1.3e-12 47.6 25.8 0.018 14.6 0.1 6.6 2 2 4 7 7 7 7 Leucine-rich repeat LRR_1 PF00560.33 PRP77145.1 - 1.6e-08 34.0 54.5 5.5 7.9 0.2 14.5 15 1 0 15 15 15 6 Leucine Rich Repeat LRR_5 PF13306.6 PRP77145.1 - 2.4e-08 34.0 10.3 0.0026 17.7 0.7 5.2 3 2 3 6 6 6 5 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 PRP77145.1 - 2.2e-06 27.3 54.5 0.71 10.1 0.2 14.2 16 0 0 16 16 16 5 Leucine Rich repeat DUF155 PF02582.14 PRP77145.1 - 0.023 14.8 0.1 1.6 8.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 MoaE PF02391.17 PRP77146.1 - 2.3e-31 108.4 0.1 4.7e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 MoaE protein MTCP1 PF08991.10 PRP77146.1 - 5.3e-10 39.4 8.0 5.3e-10 39.4 8.0 2.1 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type ThiS PF02597.20 PRP77146.1 - 3.4e-07 30.8 0.1 1.2e-06 29.1 0.0 2.0 2 0 0 2 2 2 1 ThiS family CHCH PF06747.13 PRP77146.1 - 3.7e-05 23.7 5.6 9.5e-05 22.4 5.6 1.8 1 0 0 1 1 1 1 CHCH domain BLI1 PF17324.2 PRP77146.1 - 0.023 15.3 0.0 0.086 13.5 0.0 2.0 1 0 0 1 1 1 0 BLOC-1 interactor 1 Ribosomal_L12_N PF16320.5 PRP77146.1 - 0.14 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain TIG PF01833.24 PRP77147.1 - 0.00074 19.6 0.3 0.0025 17.9 0.0 2.0 2 0 0 2 2 2 1 IPT/TIG domain LysR_substrate PF03466.20 PRP77148.1 - 0.0072 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 LysR substrate binding domain SBP_bac_11 PF13531.6 PRP77148.1 - 0.021 14.6 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein FCSD-flav_bind PF09242.11 PRP77148.1 - 0.14 12.5 0.0 3.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding PAS PF00989.25 PRP77150.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold Glyco_transf_20 PF00982.21 PRP77151.1 - 1.6e-137 459.0 0.0 2.3e-137 458.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PRP77151.1 - 3.5e-55 186.7 0.0 6.3e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase adh_short PF00106.25 PRP77151.1 - 3.6e-47 160.3 0.5 6.2e-47 159.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP77151.1 - 8e-46 156.5 0.7 4.4e-43 147.5 0.7 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_M20 PF01546.28 PRP77151.1 - 8e-36 123.7 0.0 3.2e-35 121.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PRP77151.1 - 1.4e-10 41.0 0.0 3.4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain KR PF08659.10 PRP77151.1 - 1e-08 35.3 0.6 2.4e-07 30.9 0.6 2.3 1 1 0 1 1 1 1 KR domain Peptidase_M28 PF04389.17 PRP77151.1 - 0.0016 18.2 0.2 0.047 13.4 0.0 3.1 3 0 0 3 3 3 1 Peptidase family M28 3HCDH_N PF02737.18 PRP77151.1 - 0.16 11.8 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M16_C PF05193.21 PRP77152.1 - 8e-13 48.8 0.1 2.6e-12 47.1 0.1 1.9 1 0 0 1 1 1 1 Peptidase M16 inactive domain Reprolysin_3 PF13582.6 PRP77152.1 - 0.83 10.2 2.8 1.3 9.6 0.1 2.7 3 0 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like tRNA-synt_1 PF00133.22 PRP77154.1 - 1.9e-217 723.3 0.0 3.4e-217 722.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PRP77154.1 - 3.2e-24 85.6 0.0 5.2e-23 81.7 0.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PRP77154.1 - 1.7e-16 60.0 0.9 5.9e-05 22.0 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PRP77154.1 - 0.00032 20.1 0.0 0.002 17.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF4395 PF14340.6 PRP77155.1 - 4.6e-27 94.9 8.6 4.6e-27 94.9 8.6 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4395) SQS_PSY PF00494.19 PRP77158.1 - 5.4e-53 180.2 0.0 6.7e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase LIM PF00412.22 PRP77159.1 - 4.6e-12 46.0 7.9 8.7e-12 45.1 7.9 1.5 1 0 0 1 1 1 1 LIM domain AKAP2_C PF15304.6 PRP77159.1 - 2.2 7.5 7.9 4 6.6 7.9 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus adh_short PF00106.25 PRP77160.1 - 1.1e-47 162.0 1.3 1.5e-47 161.6 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP77160.1 - 6.8e-34 117.4 0.5 8.5e-34 117.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP77160.1 - 6.7e-16 58.7 0.3 1e-15 58.1 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP77160.1 - 3.8e-06 26.5 0.1 5.3e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 PRP77160.1 - 0.0014 18.0 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 PRP77160.1 - 0.015 14.7 0.1 0.018 14.4 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PRP77160.1 - 0.016 14.3 0.3 0.021 14.0 0.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 PRP77160.1 - 0.034 13.5 0.6 0.065 12.5 0.6 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 PRP77160.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pkinase PF00069.25 PRP77161.1 - 3.4e-57 193.8 3.9 5.5e-54 183.3 0.9 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77161.1 - 1.4e-30 106.4 1.1 8.1e-29 100.7 0.3 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP77161.1 - 7.6e-05 22.2 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP77161.1 - 0.0001 21.8 0.3 0.0002 20.8 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP77161.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1959 PF09218.10 PRP77161.1 - 0.058 13.5 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) Pkinase_fungal PF17667.1 PRP77161.1 - 0.08 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Y_phosphatase2 PF03162.13 PRP77163.1 - 9.5e-48 161.9 0.1 1.7e-47 161.1 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 PRP77163.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Ank_2 PF12796.7 PRP77165.1 - 1.3e-10 41.7 0.0 6.2e-10 39.5 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) F-box-like PF12937.7 PRP77165.1 - 3.5e-08 33.2 0.2 1.6e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like Ank_3 PF13606.6 PRP77165.1 - 4.1e-08 32.9 0.1 0.0049 17.3 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP77165.1 - 4.2e-08 33.3 0.3 0.0011 19.2 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP77165.1 - 7.5e-07 29.6 0.2 0.0039 17.7 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) F-box PF00646.33 PRP77165.1 - 2.8e-05 23.9 0.0 8.3e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ank PF00023.30 PRP77165.1 - 8.5e-05 22.8 0.1 0.075 13.5 0.0 3.3 2 2 1 3 3 3 1 Ankyrin repeat FH2 PF02181.23 PRP77167.1 - 2.3e-76 257.3 2.3 2.3e-76 257.3 2.3 2.5 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PRP77167.1 - 2.3e-28 99.2 3.8 2.3e-28 99.2 3.8 1.9 1 1 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP77167.1 - 1.8e-23 83.1 0.0 1.8e-23 83.1 0.0 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain C2 PF00168.30 PRP77167.1 - 1.4e-12 47.7 0.1 3.1e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 C2 domain Tropomyosin_1 PF12718.7 PRP77167.1 - 0.0048 17.1 9.9 0.0048 17.1 9.9 3.3 3 1 0 3 3 3 1 Tropomyosin like Dynamitin PF04912.14 PRP77167.1 - 0.0092 15.3 12.8 0.021 14.2 5.4 2.4 2 0 0 2 2 2 2 Dynamitin Moulting_cycle PF04870.16 PRP77167.1 - 0.05 12.9 7.3 0.078 12.3 4.8 2.5 2 0 0 2 2 2 0 Moulting cycle Mito_fiss_reg PF05308.11 PRP77167.1 - 0.056 13.5 9.3 0.029 14.4 5.4 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator TMF_TATA_bd PF12325.8 PRP77167.1 - 0.092 13.0 12.4 0.022 14.9 4.3 3.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Myb_DNA-bind_4 PF13837.6 PRP77167.1 - 0.16 12.4 2.1 5.2 7.5 0.3 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4061 PF13270.6 PRP77167.1 - 0.21 11.9 4.2 1 9.7 4.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) LUC7 PF03194.15 PRP77167.1 - 1.1 8.8 9.3 1.5 8.5 0.3 3.6 3 1 1 4 4 4 0 LUC7 N_terminus PPI_Ypi1 PF07491.11 PRP77168.1 - 1.3e-17 63.3 11.0 3.3e-17 62.1 11.0 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor PH PF00169.29 PRP77169.1 - 7.1e-07 29.7 0.0 2.5e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 PH domain SARAF PF06682.12 PRP77169.1 - 0.068 12.8 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SAD_SRA PF02182.17 PRP77170.1 - 1.6e-36 125.4 2.3 1.5e-35 122.2 0.0 2.6 3 0 0 3 3 3 1 SAD/SRA domain PHD PF00628.29 PRP77170.1 - 2.6e-11 43.2 5.8 2.6e-11 43.2 5.8 5.3 4 2 1 5 5 2 1 PHD-finger zf-C3HC4_3 PF13920.6 PRP77170.1 - 2e-10 40.4 21.4 8.7e-09 35.1 8.2 4.7 4 1 0 4 4 3 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP77170.1 - 3.4e-08 33.2 23.0 4.4e-07 29.6 12.1 4.4 4 1 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP77170.1 - 1e-06 28.5 11.4 1e-06 28.5 11.4 5.6 5 1 1 6 6 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP77170.1 - 1.1e-05 25.4 5.7 1.1e-05 25.4 5.7 4.6 5 0 0 5 5 5 2 RING-type zinc-finger zf-RING_2 PF13639.6 PRP77170.1 - 2.4e-05 24.6 10.4 2.4e-05 24.6 10.4 4.8 4 0 0 4 4 3 2 Ring finger domain zf-RING_5 PF14634.6 PRP77170.1 - 3.6e-05 23.6 9.4 3.6e-05 23.6 9.4 5.3 4 2 1 5 5 4 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PRP77170.1 - 9.2e-05 22.5 10.7 9.2e-05 22.5 10.7 4.5 4 1 0 4 4 2 2 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PRP77170.1 - 0.00039 20.2 8.5 0.00039 20.2 8.5 4.6 5 1 0 5 5 4 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PRP77170.1 - 0.0011 19.1 5.2 0.0011 19.1 5.2 4.4 4 1 0 4 4 3 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 PRP77170.1 - 0.013 15.3 2.9 0.013 15.3 2.9 3.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein PHD_2 PF13831.6 PRP77170.1 - 0.019 14.5 1.1 0.019 14.5 1.1 3.4 3 0 0 3 3 3 0 PHD-finger Homeodomain PF00046.29 PRP77172.1 - 7.2e-16 57.8 2.1 9.5e-16 57.4 2.1 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP77172.1 - 1.4e-05 24.9 1.1 1.4e-05 24.9 1.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain PLC-beta_C PF08703.10 PRP77172.1 - 0.081 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 PLC-beta C terminal Gly_transf_sug PF04488.15 PRP77173.1 - 4.9e-10 39.9 0.5 1.3e-09 38.6 0.5 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PRP77173.1 - 0.00019 20.9 0.4 0.00026 20.5 0.4 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein G8 PF10162.9 PRP77174.1 - 2.7e-28 98.5 0.5 6.1e-28 97.4 0.5 1.7 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP77174.1 - 0.00011 22.1 0.1 0.00011 22.1 0.1 3.5 2 1 0 2 2 2 1 Right handed beta helix region Imm-NTF2 PF15655.6 PRP77174.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 NTF2 fold immunity protein MRI PF15325.6 PRP77175.1 - 1.2 10.3 8.9 7.8 7.6 0.0 2.5 2 1 0 2 2 2 0 Modulator of retrovirus infection PEMT PF04191.13 PRP77176.1 - 1.9e-28 98.9 2.1 1.9e-28 98.9 2.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase HA PF03457.14 PRP77178.1 - 2.2e-08 34.3 7.2 6.9e-08 32.7 0.5 3.4 3 1 0 3 3 3 2 Helicase associated domain MCD PF05292.11 PRP77178.1 - 1.7 8.1 10.2 0.36 10.4 3.9 2.6 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Tyr_Deacylase PF02580.16 PRP77179.1 - 3.9e-38 131.2 0.1 1.2e-37 129.7 0.1 1.8 1 1 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PhyH PF05721.13 PRP77179.1 - 4e-09 37.1 0.0 7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3652 PF12372.8 PRP77181.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Huntingtin protein region GPS PF01825.21 PRP77183.1 - 1.3e-06 28.8 1.0 2.8e-06 27.8 1.0 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF2970 PF11174.8 PRP77183.1 - 0.0083 16.0 0.3 0.014 15.2 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2970) Collectrin PF16959.5 PRP77183.1 - 0.092 12.5 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 Renal amino acid transporter Syndecan PF01034.20 PRP77183.1 - 0.41 10.6 1.4 0.68 9.9 1.4 1.2 1 0 0 1 1 1 0 Syndecan domain Cellulase PF00150.18 PRP77185.1 - 7.2e-17 61.7 2.8 9.9e-17 61.3 2.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ChiC PF06483.11 PRP77186.1 - 0.096 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Chitinase C Abhydrolase_1 PF00561.20 PRP77187.1 - 7.9e-16 58.5 0.4 2e-15 57.2 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP77187.1 - 6.8e-14 51.7 0.0 1.3e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP77187.1 - 4.2e-07 30.8 0.7 5.9e-07 30.3 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 PRP77187.1 - 0.00041 19.9 0.2 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Na_H_antiport_1 PF06965.12 PRP77187.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter 1 Ser_hydrolase PF06821.13 PRP77187.1 - 0.058 13.2 0.1 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase ECR1_N PF14382.6 PRP77188.1 - 2.5e-14 52.8 0.5 5.4e-14 51.7 0.5 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 PRP77188.1 - 1.8e-10 41.0 0.1 3.7e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 KH domain LRR_6 PF13516.6 PRP77190.1 - 3.7e-17 60.8 18.1 0.00041 20.2 0.2 6.4 6 0 0 6 6 6 6 Leucine Rich repeat LRR_1 PF00560.33 PRP77190.1 - 0.00045 20.4 8.6 0.87 10.4 0.3 4.9 5 0 0 5 5 5 2 Leucine Rich Repeat DUF2202 PF09968.9 PRP77190.1 - 0.0033 17.3 1.5 2.1 8.2 0.1 3.1 1 1 1 2 2 2 2 Uncharacterized protein domain (DUF2202) DUF3361 PF11841.8 PRP77190.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) LRR_4 PF12799.7 PRP77190.1 - 3.5 8.2 22.7 7.4 7.1 9.0 4.4 2 2 0 3 3 3 0 Leucine Rich repeats (2 copies) Rubis-subs-bind PF09273.11 PRP77191.1 - 9.8e-26 91.0 0.1 1.4e-12 48.4 0.0 2.6 2 0 0 2 2 2 2 Rubisco LSMT substrate-binding SET PF00856.28 PRP77191.1 - 4.5e-07 30.4 0.0 8.2e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 SET domain zf-TAZ PF02135.16 PRP77192.1 - 0.14 12.6 4.9 0.28 11.7 4.9 1.5 1 0 0 1 1 1 0 TAZ zinc finger SET PF00856.28 PRP77193.1 - 0.00016 22.1 1.0 0.00042 20.7 0.2 2.4 2 1 0 2 2 2 1 SET domain zf-HIT PF04438.16 PRP77194.1 - 0.00084 19.2 4.7 0.0015 18.3 4.7 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 PRP77194.1 - 0.0053 14.7 1.5 0.0067 14.4 1.5 1.2 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 C1_2 PF03107.16 PRP77194.1 - 0.017 15.4 3.9 0.034 14.5 3.9 1.5 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 PRP77194.1 - 0.21 11.8 4.6 0.4 10.9 4.6 1.4 1 0 0 1 1 1 0 B-box zinc finger DZR PF12773.7 PRP77194.1 - 0.36 10.9 5.3 0.68 10.0 5.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon TERB2 PF15101.6 PRP77194.1 - 2.4 8.2 5.5 5.6 7.0 5.5 1.6 1 1 0 1 1 1 0 Telomere-associated protein TERB2 Homeodomain PF00046.29 PRP77196.1 - 4.8e-07 29.5 0.7 7.2e-07 29.0 0.2 1.6 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP77196.1 - 0.0024 17.7 0.5 0.0044 16.9 0.3 1.6 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 PRP77196.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 1 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_23 PF13384.6 PRP77196.1 - 0.081 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Med10 PF09748.9 PRP77197.1 - 4.2e-25 88.1 0.6 4.2e-25 88.1 0.6 2.2 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex Homeobox_KN PF05920.11 PRP77197.1 - 6.5e-15 54.7 0.1 2.3e-14 53.0 0.1 2.0 1 0 0 1 1 1 1 Homeobox KN domain PBC PF03792.13 PRP77197.1 - 2.3e-14 53.6 2.8 2.3e-14 53.6 2.8 2.5 3 0 0 3 3 3 1 PBC domain Homeodomain PF00046.29 PRP77197.1 - 2.5e-10 40.1 0.6 7.4e-10 38.5 0.1 2.2 2 0 0 2 2 2 1 Homeodomain YdaS_antitoxin PF15943.5 PRP77197.1 - 0.0053 16.6 0.0 0.036 13.9 0.0 2.4 3 0 0 3 3 3 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT CENP-B_N PF04218.13 PRP77197.1 - 0.052 13.2 0.7 0.33 10.6 0.2 2.5 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain MA3 PF02847.17 PRP77197.1 - 0.089 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 MA3 domain CdvA PF18822.1 PRP77197.1 - 1 9.2 7.9 1.1 9.1 3.1 2.7 2 0 0 2 2 2 0 CdvA-like coiled-coil domain FAM184 PF15665.5 PRP77197.1 - 2.3 8.0 8.8 0.26 11.0 1.4 2.4 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B Pkip-1 PF06878.11 PRP77197.1 - 3.7 7.6 9.2 3.8 7.6 5.6 2.6 2 1 0 2 2 2 0 Pkip-1 protein Porin_3 PF01459.22 PRP77198.1 - 5.9e-30 104.6 2.3 7.8e-30 104.2 2.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin UL45 PF05473.12 PRP77199.1 - 0.00041 20.1 1.9 0.36 10.4 0.1 2.4 2 0 0 2 2 2 2 UL45 protein, carbohydrate-binding C-type lectin-like fn3 PF00041.21 PRP77199.1 - 0.0023 18.2 2.1 0.0023 18.2 2.1 3.8 3 2 0 3 3 3 1 Fibronectin type III domain Binary_toxB PF03495.14 PRP77199.1 - 0.12 12.6 1.3 22 5.3 0.1 2.8 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain TSP_3 PF02412.18 PRP77199.1 - 2.7 7.7 8.5 14 5.4 1.1 2.8 2 0 0 2 2 2 0 Thrombospondin type 3 repeat Big_1 PF02369.16 PRP77199.1 - 8.9 6.4 17.3 3.2 7.8 2.0 4.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) Polyketide_cyc2 PF10604.9 PRP77201.1 - 3.3e-12 46.9 0.0 3.5e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 PRP77201.1 - 2.1e-06 28.0 0.0 2.5e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 PRP77201.1 - 0.031 14.5 0.1 0.041 14.1 0.1 1.4 1 1 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Carb_bind PF10645.9 PRP77203.1 - 0.029 14.6 22.4 0.047 13.9 16.5 3.2 1 1 1 2 2 2 0 Carbohydrate binding Mog1 PF04603.12 PRP77205.1 - 3.7e-37 127.8 0.2 4.6e-37 127.5 0.2 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DEAD PF00270.29 PRP77206.1 - 2.8e-35 121.6 0.0 7.5e-35 120.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP77206.1 - 3.5e-24 85.3 0.5 4e-22 78.6 0.2 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP77206.1 - 4.3e-11 43.1 0.0 1.5e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 PRP77206.1 - 0.0011 17.7 0.2 0.0021 16.8 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 PRP77206.1 - 0.0024 17.6 0.1 0.0041 16.8 0.1 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase NACHT PF05729.12 PRP77206.1 - 0.0092 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Helicase_C_2 PF13307.6 PRP77206.1 - 0.014 15.6 0.0 0.067 13.4 0.0 1.9 2 0 0 2 2 2 0 Helicase C-terminal domain T4SS-DNA_transf PF02534.14 PRP77206.1 - 0.043 12.6 0.0 0.08 11.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Flavi_DEAD PF07652.14 PRP77206.1 - 0.056 13.4 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Arginase PF00491.21 PRP77207.1 - 1.2e-45 156.2 0.0 1.4e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family Gemini_AC4_5 PF04807.12 PRP77207.1 - 0.19 11.5 0.3 0.38 10.5 0.3 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region WD40 PF00400.32 PRP77209.1 - 2.3 9.2 8.3 73 4.5 0.0 3.8 3 1 0 3 3 3 0 WD domain, G-beta repeat ATP-synt_8 PF00895.20 PRP77210.1 - 0.017 15.5 0.1 0.018 15.5 0.1 1.1 1 0 0 1 1 1 0 ATP synthase protein 8 DUF1003 PF06210.11 PRP77213.1 - 7.7 6.7 6.7 0.58 10.3 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) MFS_1 PF07690.16 PRP77215.1 - 1e-33 116.7 32.0 1e-33 116.7 32.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Erg28 PF03694.13 PRP77215.1 - 1.1e-28 99.8 0.3 1.1e-28 99.8 0.3 2.3 2 0 0 2 2 2 1 Erg28 like protein Ig_mannosidase PF17753.1 PRP77216.1 - 4.2e-14 52.0 0.0 1.7e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 PRP77216.1 - 6.9e-09 36.2 0.0 1.8e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2_N PF02837.18 PRP77216.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain DUF1947 PF09183.10 PRP77216.1 - 0.045 14.1 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Gelsolin PF00626.22 PRP77217.1 - 4.3e-38 129.1 0.0 8e-14 51.3 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat C2 PF00168.30 PRP77217.1 - 1.6e-20 73.3 0.0 3.4e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 C2 domain Apolipoprotein PF01442.18 PRP77219.1 - 0.017 15.0 7.3 0.03 14.2 7.3 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PSK_trans_fac PF07704.11 PRP77219.1 - 0.41 11.4 4.4 1.4 9.8 4.4 1.8 1 1 0 1 1 1 0 Rv0623-like transcription factor DUF1451 PF07295.11 PRP77219.1 - 0.59 10.2 4.6 0.74 9.8 4.6 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain Rpn9_C PF18261.1 PRP77219.1 - 1.8 8.2 5.2 0.32 10.6 0.4 2.3 2 1 1 3 3 3 0 Rpn9 C-terminal helix TM_helix PF05552.12 PRP77221.1 - 0.18 11.8 2.6 0.19 11.7 0.9 1.9 2 0 0 2 2 2 0 Conserved TM helix UPF0182 PF03699.13 PRP77221.1 - 0.8 7.8 7.7 1.1 7.4 7.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) ABC2_membrane_2 PF12679.7 PRP77221.1 - 1.5 8.0 12.0 1.8 7.8 12.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein PARG_cat PF05028.14 PRP77223.1 - 1.3e-16 60.9 0.1 2.1e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) cNMP_binding PF00027.29 PRP77224.1 - 3e-11 43.2 0.0 7.2e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain SHMT PF00464.19 PRP77226.1 - 6.9e-186 617.6 0.0 8e-186 617.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 PRP77226.1 - 1.8e-05 24.1 0.0 3.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4142 PF13628.6 PRP77226.1 - 0.13 12.5 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Choline_kinase PF01633.20 PRP77227.1 - 7.2e-49 166.3 0.8 9.7e-49 165.8 0.8 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PRP77227.1 - 0.0033 17.4 0.0 0.0078 16.2 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family MORN PF02493.20 PRP77228.1 - 1.2e-29 100.4 30.9 3.5e-05 23.4 0.6 7.3 7 0 0 7 7 7 7 MORN repeat DUF1579 PF07617.11 PRP77228.1 - 0.0047 16.9 4.7 0.34 10.8 0.1 2.7 1 1 1 3 3 3 2 Protein of unknown function (DUF1579) zf-MIZ PF02891.20 PRP77229.1 - 2.2e-12 46.5 4.1 2.4e-12 46.4 2.1 2.1 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger FYRN PF05964.14 PRP77229.1 - 3.6e-11 42.7 0.0 8.9e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 PRP77229.1 - 2.6e-08 33.9 0.0 8.4e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 F/Y rich C-terminus zf-Nse PF11789.8 PRP77229.1 - 0.25 11.2 0.9 0.75 9.7 0.9 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit EF-hand_1 PF00036.32 PRP77230.1 - 8.2e-15 53.2 0.4 4.2e-05 22.8 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 PRP77230.1 - 2.5e-14 52.0 0.1 0.00013 21.3 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PRP77230.1 - 4.1e-13 48.1 0.1 0.0038 17.1 0.3 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PRP77230.1 - 3.6e-12 46.5 0.0 4.5e-07 30.2 0.0 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP77230.1 - 4.6e-10 39.2 0.1 0.00044 20.1 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_10 PF14788.6 PRP77230.1 - 0.081 12.8 0.1 53 3.8 0.0 3.2 3 0 0 3 3 3 0 EF hand Ribosomal_L18 PF17135.4 PRP77231.1 - 3.4e-76 254.8 2.2 4.2e-76 254.5 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 PRP77231.1 - 0.011 16.4 0.2 0.019 15.6 0.2 1.5 1 0 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GlnE PF03710.15 PRP77231.1 - 0.14 11.5 0.0 0.58 9.5 0.0 1.8 2 0 0 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase Mito_carr PF00153.27 PRP77232.1 - 5.3e-50 167.3 2.1 2.2e-23 82.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TA0956 PF11513.8 PRP77233.1 - 0.088 13.0 0.2 0.22 11.7 0.2 1.7 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 DUF1474 PF07342.11 PRP77233.1 - 3.7 8.1 5.1 1.7 9.2 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1474) RhoGEF PF00621.20 PRP77236.1 - 3.1e-48 164.4 2.6 5.9e-48 163.5 2.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PRP77236.1 - 5.3e-08 33.3 0.9 0.0049 17.3 0.1 2.8 1 1 0 2 2 2 2 PH domain IQ_SEC7_PH PF16453.5 PRP77236.1 - 4.5e-05 23.4 0.1 0.03 14.3 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 PRP77236.1 - 0.0049 16.7 0.7 1.5 8.6 0.1 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain zf-C2H2_4 PF13894.6 PRP77236.1 - 0.013 16.3 0.2 0.066 14.1 0.2 2.4 1 0 0 1 1 1 0 C2H2-type zinc finger Sina PF03145.16 PRP77236.1 - 0.019 15.0 0.4 0.29 11.1 0.1 2.4 2 0 0 2 2 2 0 Seven in absentia protein family zf-C2H2 PF00096.26 PRP77236.1 - 0.038 14.5 0.2 0.12 12.9 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type PH_6 PF15406.6 PRP77236.1 - 0.073 13.4 0.1 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_transf_22 PF03901.17 PRP77237.1 - 7.2e-81 272.5 33.8 1e-80 272.0 33.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4746 PF15928.5 PRP77237.1 - 0.51 9.7 7.8 0.79 9.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ribosomal_60s PF00428.19 PRP77237.1 - 3.2 8.4 13.6 7 7.3 13.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DOMON PF03351.17 PRP77239.1 - 1.3e-23 83.6 3.8 2.3e-23 82.8 3.8 1.4 1 0 0 1 1 1 1 DOMON domain RNase_PH PF01138.21 PRP77240.1 - 7.8e-18 65.2 0.0 3.2e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PRP77240.1 - 4.1e-15 55.6 0.4 9.7e-15 54.4 0.1 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 BTD PF09270.10 PRP77240.1 - 0.1 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain Ndc1_Nup PF09531.10 PRP77241.1 - 0.0022 16.8 0.0 0.0025 16.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup tRNA-synt_2d PF01409.20 PRP77241.1 - 0.05 13.1 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Lipase_3 PF01764.25 PRP77242.1 - 2.2e-13 50.3 0.0 5.2e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 PRP77242.1 - 2.1e-05 24.4 0.0 4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein SAM_3 PF18016.1 PRP77242.1 - 0.032 14.1 0.2 4 7.3 0.0 2.9 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Zeta_toxin PF06414.12 PRP77242.1 - 0.049 12.9 0.1 1.7 7.8 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin Hydrolase_4 PF12146.8 PRP77242.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pro_CA PF00484.19 PRP77242.1 - 0.077 13.3 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Carbonic anhydrase ABC_tran PF00005.27 PRP77242.1 - 0.097 13.2 0.1 0.21 12.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 PRP77242.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Cellulase PF00150.18 PRP77243.1 - 2.2e-45 155.3 3.9 2.2e-45 155.3 3.9 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Ferric_reduct PF01794.19 PRP77243.1 - 5.6e-25 87.9 14.2 2.9e-24 85.6 11.6 2.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DOMON PF03351.17 PRP77243.1 - 1.4e-23 83.4 0.8 3e-23 82.4 0.8 1.6 1 0 0 1 1 1 1 DOMON domain NAD_binding_6 PF08030.12 PRP77243.1 - 2.2e-17 63.6 0.0 5.9e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PRP77243.1 - 5.4e-14 52.2 0.0 1.9e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 PRP77243.1 - 2.3e-07 31.4 0.0 4.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PRP77243.1 - 0.0013 19.0 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain zf-C3HC4_2 PF13923.6 PRP77246.1 - 9.7e-12 44.5 10.3 1.5e-11 44.0 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP77246.1 - 6e-09 35.6 10.9 9.9e-09 34.9 10.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 PRP77246.1 - 8.4e-09 36.0 0.0 2.4e-08 34.5 0.1 1.7 2 0 0 2 2 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_2 PF13639.6 PRP77246.1 - 1.9e-07 31.3 9.0 3.1e-07 30.6 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP77246.1 - 1.8e-06 27.7 7.0 3.1e-06 26.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP77246.1 - 1e-05 25.5 6.7 2.1e-05 24.5 6.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP77246.1 - 1.9e-05 24.5 9.2 3.4e-05 23.7 9.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PRP77246.1 - 9e-05 22.7 5.3 0.00018 21.8 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 PRP77246.1 - 0.00023 21.0 2.5 0.00036 20.3 2.5 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 PRP77246.1 - 0.00032 20.8 8.9 0.00057 20.0 8.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PRP77246.1 - 0.0063 16.3 6.0 0.013 15.4 6.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PRP77246.1 - 0.017 15.3 6.0 0.029 14.5 6.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 PRP77246.1 - 0.017 14.9 4.7 0.037 13.9 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.11 PRP77246.1 - 0.13 12.4 4.4 0.24 11.5 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 PRP77246.1 - 0.57 10.2 4.2 1.1 9.4 4.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 PRP77246.1 - 1.4 8.7 7.9 4 7.3 7.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RsfS PF02410.15 PRP77247.1 - 1.6e-17 63.8 0.1 2.8e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation LPP20 PF02169.16 PRP77247.1 - 0.075 13.4 0.1 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 LPP20 lipoprotein Rho_GDI PF02115.17 PRP77248.1 - 2.4e-62 210.2 1.3 3.2e-62 209.8 1.3 1.1 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor EMP24_GP25L PF01105.24 PRP77250.1 - 3e-46 157.6 0.0 4.4e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 PRP77250.1 - 0.033 14.4 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain DUF348 PF03990.14 PRP77250.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain AAA PF00004.29 PRP77251.1 - 0.00066 20.1 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ORC2 PF04084.14 PRP77251.1 - 0.047 12.6 0.2 0.074 11.9 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 AAA_16 PF13191.6 PRP77251.1 - 0.073 13.5 0.1 0.52 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain DUF4165 PF13752.6 PRP77252.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) MFS_1 PF07690.16 PRP77253.1 - 4.7e-32 111.3 31.7 4.6e-18 65.3 18.2 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 PRP77253.1 - 9.3e-09 34.6 20.3 2.8e-06 26.4 12.0 2.8 1 1 2 3 3 3 3 MFS_1 like family MFS_2 PF13347.6 PRP77253.1 - 5.9e-08 31.7 23.9 1.9e-06 26.7 10.2 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein RhoGEF PF00621.20 PRP77255.1 - 3e-49 167.8 0.7 7.4e-49 166.5 0.7 1.8 1 0 0 1 1 1 1 RhoGEF domain ArfGap PF01412.18 PRP77255.1 - 9.4e-26 90.2 0.3 9.4e-26 90.2 0.3 3.0 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf NLE PF08154.12 PRP77255.1 - 5.2e-18 65.3 0.6 1.3e-17 64.1 0.1 2.0 2 0 0 2 2 2 1 NLE (NUC135) domain WD40 PF00400.32 PRP77255.1 - 7.8e-18 64.5 18.6 0.0064 17.3 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat CH PF00307.31 PRP77255.1 - 3.7e-17 62.5 0.4 4.1e-16 59.1 0.1 2.7 2 0 0 2 2 2 1 Calponin homology (CH) domain PH PF00169.29 PRP77255.1 - 3.7e-12 46.7 1.3 1.1e-06 29.1 0.1 4.3 3 1 0 3 3 3 2 PH domain EF-hand_5 PF13202.6 PRP77256.1 - 2.5e-08 33.0 9.1 0.41 10.2 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.32 PRP77256.1 - 2.9e-08 32.7 8.4 0.41 10.3 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PRP77256.1 - 7e-08 32.8 2.7 4.4 7.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PRP77256.1 - 2.8e-06 26.8 10.2 1.6 8.9 0.3 4.3 4 0 0 4 4 4 4 EF-hand domain Dockerin_1 PF00404.18 PRP77256.1 - 2.9e-05 24.2 5.3 0.94 9.7 0.9 3.8 3 1 1 4 4 4 2 Dockerin type I domain EF-hand_8 PF13833.6 PRP77256.1 - 0.00062 19.6 2.9 12 5.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair LCIB_C_CA PF18599.1 PRP77256.1 - 0.0008 18.8 7.3 0.076 12.3 0.9 2.3 1 1 1 2 2 2 2 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Excalibur PF05901.11 PRP77256.1 - 0.31 11.7 3.1 1e+02 3.6 0.0 4.0 4 0 0 4 4 4 0 Excalibur calcium-binding domain DUF676 PF05057.14 PRP77257.1 - 3.2e-37 128.2 0.0 7.1e-37 127.0 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PRP77257.1 - 2.6e-07 30.7 0.0 4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 PRP77257.1 - 0.00011 22.0 0.1 0.00079 19.2 0.0 2.3 2 1 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 PRP77257.1 - 0.00046 19.5 0.0 0.00076 18.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase TPR_2 PF07719.17 PRP77258.1 - 8.1e-53 172.3 35.2 0.00015 21.6 0.0 17.5 17 0 0 17 17 17 10 Tetratricopeptide repeat TPR_1 PF00515.28 PRP77258.1 - 2.6e-45 150.4 41.7 5e-05 22.9 0.2 17.1 20 0 0 20 20 20 10 Tetratricopeptide repeat TPR_19 PF14559.6 PRP77258.1 - 2.5e-37 127.2 4.3 0.00013 22.4 0.0 12.3 10 2 3 13 13 13 7 Tetratricopeptide repeat TPR_14 PF13428.6 PRP77258.1 - 4.3e-37 123.6 3.2 0.0029 18.3 0.0 15.7 9 4 7 16 16 16 9 Tetratricopeptide repeat TPR_12 PF13424.6 PRP77258.1 - 8.8e-36 122.1 15.4 1.7e-06 28.2 0.1 11.9 8 4 3 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 PRP77258.1 - 9.8e-35 118.9 0.0 4e-05 24.2 0.0 11.4 9 3 2 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 PRP77258.1 - 1.6e-30 104.5 18.0 7e-05 22.4 0.0 12.7 13 3 3 16 16 16 7 TPR repeat TPR_8 PF13181.6 PRP77258.1 - 2.9e-30 101.9 28.3 0.015 15.5 0.0 15.8 18 0 0 18 18 16 9 Tetratricopeptide repeat TPR_17 PF13431.6 PRP77258.1 - 1.5e-24 84.6 28.7 0.78 10.3 0.1 16.1 17 1 0 17 17 14 7 Tetratricopeptide repeat TPR_7 PF13176.6 PRP77258.1 - 1.5e-23 81.0 9.2 0.012 15.5 0.1 13.5 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_6 PF13174.6 PRP77258.1 - 3.2e-21 74.5 13.2 0.0024 18.4 0.0 14.0 16 0 0 16 16 14 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP77258.1 - 2.1e-13 50.3 22.6 0.00025 21.2 0.0 8.1 5 3 3 8 8 8 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PRP77258.1 - 8.9e-13 48.2 0.0 0.011 15.9 0.0 8.1 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 PRP77258.1 - 1.1e-10 41.0 20.2 0.49 10.3 0.0 11.8 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_4 PF07721.14 PRP77258.1 - 2.2e-05 24.7 0.3 15 6.6 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat NARP1 PF12569.8 PRP77258.1 - 0.00015 20.8 0.1 0.00015 20.8 0.1 7.8 4 3 4 8 8 4 2 NMDA receptor-regulated protein 1 HemY_N PF07219.13 PRP77258.1 - 0.23 11.7 2.2 2.5 8.3 0.1 3.8 3 0 0 3 3 2 0 HemY protein N-terminus Sybindin PF04099.12 PRP77259.1 - 3.1e-37 127.7 0.3 3.4e-37 127.5 0.3 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 PRP77259.1 - 2.7e-05 24.3 0.4 4.1e-05 23.7 0.4 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 PRP77260.1 - 7.3e-45 153.4 0.0 1.2e-44 152.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77260.1 - 5.9e-16 58.5 0.0 9.6e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP77260.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like IQ PF00612.27 PRP77260.1 - 0.0092 15.7 2.0 0.028 14.2 2.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif APH PF01636.23 PRP77260.1 - 0.026 14.5 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hat1_N PF10394.9 PRP77261.1 - 4.8e-38 130.9 0.9 1.1e-37 129.7 0.9 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus SesA PF17107.5 PRP77261.1 - 0.03 14.5 0.2 0.059 13.6 0.2 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FapA PF03961.13 PRP77261.1 - 0.24 9.9 5.6 0.44 9.1 5.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Homeodomain PF00046.29 PRP77263.1 - 7.6e-16 57.7 4.0 1.6e-15 56.7 4.0 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PRP77263.1 - 0.12 11.8 0.2 0.3 10.6 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Nop25 PF09805.9 PRP77263.1 - 0.4 11.1 6.7 0.61 10.6 6.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CN_hydrolase PF00795.22 PRP77264.1 - 3.2e-19 69.3 0.0 3.8e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Ras PF00071.22 PRP77265.1 - 7e-50 168.8 0.0 8.7e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP77265.1 - 3.8e-16 59.4 0.0 6.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP77265.1 - 3.8e-11 42.8 0.0 4.7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP77265.1 - 0.0014 18.2 0.0 0.003 17.1 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PRP77265.1 - 0.0083 15.7 0.1 0.021 14.3 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 PRP77265.1 - 0.13 12.5 0.1 4.2 7.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 PRP77265.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ras PF00071.22 PRP77266.1 - 1.5e-44 151.5 0.1 1.7e-44 151.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP77266.1 - 6.9e-13 48.9 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP77266.1 - 1.2e-09 37.8 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 PRP77266.1 - 0.00013 21.6 0.1 0.00078 19.0 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP77266.1 - 0.0012 18.8 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP77266.1 - 0.027 14.0 0.1 0.063 12.8 0.1 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP77266.1 - 0.032 14.3 0.0 0.048 13.8 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase POC3_POC4 PF10448.9 PRP77266.1 - 0.065 13.3 0.2 0.08 12.9 0.2 1.5 1 1 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 PglD_N PF17836.1 PRP77266.1 - 0.083 13.5 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 PglD N-terminal domain START PF01852.19 PRP77267.1 - 2.5e-16 59.7 0.0 3.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 START domain 7TMR-DISM_7TM PF07695.11 PRP77268.1 - 0.00036 20.5 12.9 0.0033 17.3 13.6 1.8 1 1 1 2 2 2 2 7TM diverse intracellular signalling DUF3522 PF12036.8 PRP77268.1 - 0.024 14.9 3.0 0.031 14.5 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) Pr_beta_C PF12465.8 PRP77268.1 - 0.028 13.8 0.3 0.06 12.8 0.3 1.5 1 0 0 1 1 1 0 Proteasome beta subunits C terminal CPP1-like PF11833.8 PRP77268.1 - 0.083 12.5 2.6 0.087 12.5 1.6 1.6 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF423 PF04241.15 PRP77268.1 - 0.094 12.9 1.6 0.2 11.9 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Costars PF14705.6 PRP77269.1 - 0.014 15.5 0.0 0.026 14.7 0.0 1.5 1 1 0 1 1 1 0 Costars Phospholip_B PF04916.13 PRP77270.1 - 0.077 11.6 0.2 0.13 10.9 0.2 1.2 1 0 0 1 1 1 0 Phospholipase B F-box-like PF12937.7 PRP77270.1 - 0.093 12.6 0.3 0.2 11.6 0.3 1.5 1 0 0 1 1 1 0 F-box-like TMEM154 PF15102.6 PRP77271.1 - 0.027 14.4 0.4 0.059 13.3 0.4 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF2207 PF09972.9 PRP77271.1 - 0.047 12.4 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Isy1 PF06246.12 PRP77272.1 - 4.8e-70 236.0 11.2 6.5e-70 235.6 11.2 1.2 1 0 0 1 1 1 1 Isy1-like splicing family KASH_CCD PF14662.6 PRP77272.1 - 0.13 12.1 5.4 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH F-box PF00646.33 PRP77273.1 - 1.1e-07 31.5 2.5 2e-07 30.7 2.5 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP77273.1 - 1.5e-07 31.2 0.4 2.9e-07 30.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like PP2 PF14299.6 PRP77273.1 - 2.9e-07 30.7 0.1 5e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Phloem protein 2 F-box_4 PF15966.5 PRP77273.1 - 9.9e-05 22.2 0.5 0.00022 21.1 0.5 1.6 1 0 0 1 1 1 1 F-box Kelch_4 PF13418.6 PRP77275.1 - 8.9e-12 44.8 0.7 4.1e-06 26.7 0.0 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP77275.1 - 2.9e-08 33.5 0.5 0.00037 20.4 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 PRP77275.1 - 5.4e-08 32.5 6.5 1.8e-05 24.5 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 PRP77275.1 - 9e-08 31.6 0.0 0.0051 16.4 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 PRP77275.1 - 3.4e-06 27.1 0.1 0.065 13.5 0.0 3.5 2 1 1 3 3 3 2 Kelch motif Kelch_3 PF13415.6 PRP77275.1 - 0.00015 21.9 0.8 1 9.7 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain PQQ_3 PF13570.6 PRP77275.1 - 0.076 13.5 0.0 2.6 8.7 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain LRAT PF04970.13 PRP77275.1 - 0.15 12.4 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 Lecithin retinol acyltransferase Laminin_G_3 PF13385.6 PRP77276.1 - 5.3e-37 127.3 4.2 3.8e-20 72.6 0.1 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Toxin_R_bind_N PF07953.12 PRP77276.1 - 1e-05 25.4 0.1 0.22 11.2 0.0 3.2 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding Laminin_G_2 PF02210.24 PRP77276.1 - 0.00053 20.6 0.0 0.5 11.0 0.0 2.3 2 0 0 2 2 2 2 Laminin G domain DUF4982 PF16355.5 PRP77276.1 - 0.033 14.1 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) DUF4183 PF13799.6 PRP77276.1 - 0.11 12.4 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) Med3 PF11593.8 PRP77276.1 - 0.79 8.8 3.2 1.4 8.0 3.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PIG-Y PF15159.6 PRP77278.1 - 2.2e-15 57.3 3.2 4.6e-15 56.3 3.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y LRR_4 PF12799.7 PRP77278.1 - 1.5e-09 38.0 11.8 7.1e-06 26.3 0.7 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP77278.1 - 1.5e-07 31.0 10.7 0.00055 19.6 0.8 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 PRP77278.1 - 8.4e-06 25.4 1.9 1.6e-05 24.5 1.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PRP77278.1 - 0.00038 20.3 11.3 1.3 9.3 0.1 5.3 5 0 0 5 5 5 3 Leucine Rich repeat Peptidase_M28 PF04389.17 PRP77279.1 - 3.5e-29 101.9 0.0 9.2e-29 100.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 PRP77279.1 - 2.2e-07 30.8 0.0 5.4e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4395 PF14340.6 PRP77280.1 - 6e-13 49.3 5.1 6e-13 49.3 5.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4395) Peptidase_S8 PF00082.22 PRP77282.1 - 5.4e-35 121.1 4.4 3.4e-25 88.9 0.4 2.5 1 1 1 2 2 2 2 Subtilase family DUF4215 PF13948.6 PRP77282.1 - 3.6e-08 33.7 18.1 0.001 19.4 5.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4215) Pkinase_Tyr PF07714.17 PRP77283.1 - 1.7e-43 148.8 0.1 3e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77283.1 - 2.1e-29 102.7 0.2 4.5e-29 101.6 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP77283.1 - 1.3e-08 35.2 6.6 3.8e-08 33.7 6.6 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Insulin_TMD PF17870.1 PRP77283.1 - 0.0013 18.8 2.7 0.0039 17.2 2.7 1.8 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Kinase-like PF14531.6 PRP77283.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like EphA2_TM PF14575.6 PRP77283.1 - 0.055 14.4 0.1 0.12 13.3 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 PRP77283.1 - 0.14 12.0 2.5 0.31 10.8 2.5 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 PRP77283.1 - 3.1 7.8 3.9 7 6.7 3.9 1.5 1 0 0 1 1 1 0 Syndecan domain NAD_binding_10 PF13460.6 PRP77284.1 - 1e-11 45.1 0.0 1.4e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PRP77284.1 - 0.00015 20.9 0.0 0.00022 20.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PRP77284.1 - 0.00027 20.5 0.0 0.00051 19.6 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 PRP77284.1 - 0.0014 19.1 0.0 0.0082 16.6 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 PRP77284.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.5 1 1 0 1 1 1 0 KR domain Shikimate_DH PF01488.20 PRP77284.1 - 0.034 14.2 0.1 0.081 13.0 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 PRP77284.1 - 0.043 12.9 0.0 0.063 12.4 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Glyco_hydro_66 PF13199.6 PRP77284.1 - 0.098 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 CPSase_L_D2 PF02786.17 PRP77285.1 - 1.3e-65 220.9 0.0 3.1e-65 219.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PRP77285.1 - 1.8e-42 144.4 0.1 5.1e-42 142.9 0.0 1.8 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PRP77285.1 - 8.9e-26 90.1 0.0 2.6e-25 88.6 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PRP77285.1 - 8.3e-16 57.6 2.3 8.3e-16 57.6 2.3 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PRP77285.1 - 9.1e-07 28.6 0.1 0.0015 18.4 0.0 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 PRP77285.1 - 1.2e-06 28.2 0.0 2.4e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PRP77285.1 - 1.1e-05 25.1 0.0 2.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 PRP77285.1 - 0.016 15.1 0.2 0.037 13.9 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 PRP77285.1 - 0.021 14.5 0.1 0.26 11.0 0.0 2.3 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 HlyD_D23 PF16576.5 PRP77285.1 - 0.03 13.5 0.1 0.49 9.6 0.0 2.2 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 PRP77285.1 - 0.12 12.4 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Glucokinase PF02685.16 PRP77286.1 - 2e-25 89.5 0.0 2.7e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 PRP77286.1 - 1.1e-07 31.6 0.1 0.0031 17.1 0.0 2.4 2 1 0 2 2 2 2 ROK family FGGY_N PF00370.21 PRP77286.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 PRP77286.1 - 0.018 14.5 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family BSP PF04450.12 PRP77286.1 - 0.13 12.0 0.0 9 6.0 0.0 2.6 3 0 0 3 3 3 0 Peptidase of plants and bacteria Pro-kuma_activ PF09286.11 PRP77287.1 - 2.3e-20 73.4 0.0 3.6e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain B_lectin PF01453.24 PRP77287.1 - 0.00088 19.8 0.4 0.085 13.4 0.0 2.5 1 1 1 2 2 2 2 D-mannose binding lectin Pkinase_Tyr PF07714.17 PRP77288.1 - 2.2e-35 122.2 0.0 2.5e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77288.1 - 3.2e-20 72.6 0.0 6.1e-20 71.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP77288.1 - 0.00021 20.7 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.25 PRP77289.1 - 1.3e-08 34.6 0.0 2.3e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP77289.1 - 1.9e-07 31.5 4.6 5.4e-07 30.0 4.6 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP77289.1 - 4.9e-07 29.3 0.0 7.8e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Baculo_PEP_C PF04513.12 PRP77289.1 - 0.0021 18.1 2.6 9.7 6.2 0.0 2.8 1 1 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus EphA2_TM PF14575.6 PRP77289.1 - 0.0052 17.6 0.2 0.012 16.4 0.2 1.6 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PRP77289.1 - 0.015 15.2 0.2 0.015 15.2 0.2 2.7 2 0 0 2 2 2 0 TMEM154 protein family PRIMA1 PF16101.5 PRP77289.1 - 0.52 10.4 4.0 0.15 12.1 0.4 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Voltage_CLC PF00654.20 PRP77290.1 - 2.8e-31 109.0 11.5 3.5e-31 108.8 11.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 PRP77290.1 - 2.1e-15 56.9 0.3 2.5e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain zf-C2H2_4 PF13894.6 PRP77292.1 - 0.044 14.6 2.1 0.2 12.6 2.1 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.15 PRP77292.1 - 0.067 13.2 0.9 0.2 11.7 0.9 1.8 1 0 0 1 1 1 0 BED zinc finger DUF4286 PF14114.6 PRP77292.1 - 0.36 11.4 3.1 0.38 11.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) zf-C2H2 PF00096.26 PRP77292.1 - 0.59 10.7 2.8 3.5 8.3 2.8 2.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pkinase PF00069.25 PRP77295.1 - 9.4e-50 169.4 0.4 6.3e-49 166.7 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77295.1 - 4.4e-37 127.8 0.2 5.4e-36 124.2 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 PRP77295.1 - 3.3e-10 40.2 0.0 8.7e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 PRP77295.1 - 9.9e-09 35.7 1.0 3.6e-08 33.9 1.0 2.1 1 1 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 PRP77295.1 - 0.00039 19.3 0.0 0.00039 19.3 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PRP77295.1 - 0.087 12.7 0.0 4.1 7.2 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family CCT PF06203.14 PRP77295.1 - 0.11 12.6 8.2 0.26 11.4 8.2 1.7 1 0 0 1 1 1 0 CCT motif PH_11 PF15413.6 PRP77295.1 - 0.16 12.4 0.2 0.16 12.4 0.2 2.4 2 1 1 3 3 3 0 Pleckstrin homology domain AAA_23 PF13476.6 PRP77295.1 - 0.56 10.7 3.8 1.3 9.5 3.8 1.5 1 0 0 1 1 1 0 AAA domain LSM PF01423.22 PRP77296.1 - 1.1e-19 69.8 1.2 1.8e-19 69.2 1.2 1.3 1 1 0 1 1 1 1 LSM domain GNAT_acetyltran PF12746.7 PRP77296.1 - 0.14 11.7 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Methyltransf_16 PF10294.9 PRP77298.1 - 4.2e-19 68.9 0.0 6.4e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PMR5N PF14416.6 PRP77298.1 - 2.3 8.6 7.4 0.37 11.1 1.4 2.4 2 0 0 2 2 2 0 PMR5 N terminal Domain Mtp PF03821.16 PRP77299.1 - 0.078 12.6 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter Biliv-reduc_cat PF09166.10 PRP77299.1 - 0.089 13.1 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Biliverdin reductase, catalytic tRNA-synt_1e PF01406.19 PRP77302.1 - 4.9e-99 331.5 2.0 1e-98 330.4 2.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PRP77302.1 - 1.1e-10 40.9 1.3 4.1e-06 25.8 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PRP77302.1 - 8.8e-06 24.3 0.0 1.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 PRP77302.1 - 0.029 14.9 0.0 0.078 13.5 0.0 1.8 1 0 0 1 1 1 0 DALR domain PPR_2 PF13041.6 PRP77303.1 - 1.4e-05 25.1 13.5 0.0037 17.4 0.1 6.4 7 1 1 8 8 8 3 PPR repeat family PPR PF01535.20 PRP77303.1 - 2e-05 24.5 12.1 0.3 11.4 0.1 6.0 7 0 0 7 7 7 4 PPR repeat Folate_rec PF03024.14 PRP77304.1 - 8.9e-13 48.5 10.6 1.1e-12 48.2 10.6 1.1 1 0 0 1 1 1 1 Folate receptor family NPC1_N PF16414.5 PRP77304.1 - 0.002 17.7 5.2 0.0026 17.4 5.2 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Ras PF00071.22 PRP77305.1 - 1e-47 161.7 0.1 1.2e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP77305.1 - 1.5e-32 112.3 0.3 2.3e-32 111.7 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP77305.1 - 5.4e-13 48.8 0.1 6.9e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP77305.1 - 1.8e-09 37.3 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP77305.1 - 3.3e-05 23.9 0.1 4.9e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PRP77305.1 - 3.5e-05 23.2 0.1 0.075 12.2 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PRP77305.1 - 6.5e-05 22.4 0.0 8.5e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 PRP77305.1 - 0.0001 22.2 0.1 0.0023 17.8 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 PRP77305.1 - 0.00011 21.8 0.1 0.0003 20.4 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 PRP77305.1 - 0.00026 20.8 0.0 0.22 11.2 0.0 2.5 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 PRP77305.1 - 0.0024 17.4 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF4998 PF16389.5 PRP77305.1 - 0.0074 15.9 0.2 0.023 14.3 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function AAA_24 PF13479.6 PRP77305.1 - 0.0088 15.8 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DLIC PF05783.11 PRP77305.1 - 0.014 14.3 0.3 2.2 7.0 0.2 2.1 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) ATPase PF06745.13 PRP77305.1 - 0.028 13.8 0.1 0.042 13.2 0.1 1.4 1 1 0 1 1 1 0 KaiC NPFF PF15085.6 PRP77305.1 - 0.033 14.5 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 Neuropeptide FF AAA PF00004.29 PRP77305.1 - 0.038 14.4 0.0 0.099 13.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VirE PF05272.11 PRP77305.1 - 0.046 13.4 0.1 3.3 7.4 0.0 2.3 1 1 1 2 2 2 0 Virulence-associated protein E MMR_HSR1_Xtn PF16897.5 PRP77305.1 - 0.056 13.5 0.1 0.086 12.9 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_15 PF13175.6 PRP77305.1 - 0.064 12.9 0.1 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PRP77305.1 - 0.065 13.5 0.0 0.084 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 PRP77305.1 - 0.067 13.1 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 PRP77305.1 - 0.076 13.4 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.13 PRP77305.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_32 PF13654.6 PRP77305.1 - 0.1 11.3 0.1 0.2 10.4 0.1 1.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PRP77305.1 - 0.11 12.4 0.0 15 5.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 PRP77305.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Fer4 PF00037.27 PRP77306.1 - 9.3e-14 50.6 15.4 8.7e-08 31.7 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 PRP77306.1 - 3.2e-12 46.8 9.4 5.3e-12 46.1 9.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 PRP77306.1 - 5.1e-11 43.3 5.8 4.7e-05 24.2 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 PRP77306.1 - 1.9e-09 37.5 4.5 0.00015 21.8 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 PRP77306.1 - 5e-09 36.5 2.0 0.00016 22.1 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 PRP77306.1 - 2.3e-08 34.0 9.3 4.1e-08 33.3 9.3 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 PRP77306.1 - 9.1e-08 32.1 21.6 1.2e-05 25.3 12.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 PRP77306.1 - 2.7e-07 30.4 16.9 0.00042 20.3 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 PRP77306.1 - 1.3e-06 28.2 12.5 0.0029 17.6 2.0 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 PRP77306.1 - 6.2e-06 26.3 10.7 0.00053 20.3 2.5 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 PRP77306.1 - 0.00048 20.6 11.5 0.11 13.0 13.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 PRP77306.1 - 0.00077 19.9 11.3 0.1 13.2 0.3 2.8 3 0 0 3 3 3 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 PRP77306.1 - 0.041 14.1 5.9 1 9.6 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 PRP77306.1 - 0.043 14.0 8.3 3.1 8.0 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 PRP77306.1 - 0.58 10.3 5.6 2.2 8.5 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 PRP77306.1 - 0.88 10.7 16.7 1.7 9.8 4.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 PRP77306.1 - 1.3 9.9 12.1 2.7 8.9 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain RraA-like PF03737.15 PRP77307.1 - 3.5e-44 150.6 0.6 3.9e-44 150.4 0.6 1.0 1 0 0 1 1 1 1 Aldolase/RraA PP2C PF00481.21 PRP77308.1 - 2.9e-61 207.3 0.1 4.5e-61 206.7 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PRP77308.1 - 0.00045 19.9 0.1 0.0018 18.0 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP77308.1 - 0.0064 16.4 0.2 0.14 12.1 0.2 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Frtz PF11768.8 PRP77308.1 - 0.021 13.1 0.0 0.3 9.3 0.0 2.0 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 PRP77308.1 - 0.09 13.7 0.1 1.7 9.7 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat WD40 PF00400.32 PRP77309.1 - 4.5e-64 210.9 24.5 2.7e-10 40.7 0.1 8.1 7 1 1 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP77309.1 - 2e-20 72.9 0.0 0.0011 19.2 0.0 5.6 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP77309.1 - 3.8e-09 35.9 1.4 0.079 11.9 0.1 5.2 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP77309.1 - 8.2e-08 32.3 0.0 3.2e-05 23.9 0.0 3.4 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PRP77309.1 - 1.1e-05 24.3 6.5 1 8.0 0.5 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 PRP77309.1 - 0.011 15.1 0.0 12 5.1 0.0 3.0 3 0 0 3 3 3 0 WD40-like domain Frtz PF11768.8 PRP77309.1 - 0.012 13.9 0.0 0.037 12.4 0.0 1.8 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz ribosomal_L24 PF17136.4 PRP77310.1 - 2.6e-17 63.0 1.4 4e-17 62.4 0.1 2.0 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 PRP77310.1 - 1.2e-08 34.5 3.3 2.6e-08 33.5 3.3 1.6 1 0 0 1 1 1 1 KOW motif GTP_EFTU_D2 PF03144.25 PRP77310.1 - 0.032 14.6 0.5 0.066 13.6 0.2 1.7 2 0 0 2 2 2 0 Elongation factor Tu domain 2 Hexapep PF00132.24 PRP77311.1 - 4.4e-09 35.7 7.8 0.00084 19.0 0.1 3.9 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PRP77311.1 - 0.00026 20.7 5.2 0.26 11.1 0.1 2.7 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Arm PF00514.23 PRP77312.1 - 5.5e-66 216.8 15.5 2.4e-12 46.5 0.0 8.6 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat cNMP_binding PF00027.29 PRP77312.1 - 4e-32 110.1 0.5 3.5e-16 59.0 0.1 2.9 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain HEAT_EZ PF13513.6 PRP77312.1 - 6e-19 68.2 1.7 1.4e-06 28.6 0.0 4.7 4 0 0 4 4 4 3 HEAT-like repeat Arm_3 PF16186.5 PRP77312.1 - 8.1e-17 60.5 2.3 8.1e-17 60.5 2.3 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 PRP77312.1 - 1.5e-13 51.0 0.0 2.1e-05 24.8 0.0 4.9 2 2 3 5 5 5 4 HEAT repeats IBB PF01749.20 PRP77312.1 - 1.6e-13 50.9 0.8 1.6e-13 50.9 0.8 2.3 2 0 0 2 2 1 1 Importin beta binding domain HEAT PF02985.22 PRP77312.1 - 3.7e-13 48.5 0.6 0.00085 19.4 0.0 6.8 8 0 0 8 8 8 2 HEAT repeat Atx10homo_assoc PF09759.9 PRP77312.1 - 0.00056 19.9 0.3 0.097 12.7 0.0 3.6 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 PRP77312.1 - 0.0017 18.3 0.4 0.037 14.0 0.0 2.8 2 1 2 4 4 4 1 Domain of unknown function (DUF3361) Arm_2 PF04826.13 PRP77312.1 - 0.0042 16.6 0.8 1.2 8.5 0.1 3.8 1 1 4 5 5 5 1 Armadillo-like HEAT_PBS PF03130.16 PRP77312.1 - 0.044 14.5 0.2 24 6.0 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 PRP77312.1 - 0.21 11.9 1.4 6.5 7.1 0.0 3.7 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Ank_4 PF13637.6 PRP77314.1 - 0.14 12.7 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) LMBR1 PF04791.16 PRP77317.1 - 0.15 10.9 0.3 0.13 11.2 0.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Fer2 PF00111.27 PRP77318.1 - 7.1e-09 35.5 0.1 1.1e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Filament PF00038.21 PRP77319.1 - 6e-05 22.8 28.3 0.0019 17.8 14.1 2.4 1 1 1 2 2 2 2 Intermediate filament protein Fez1 PF06818.15 PRP77319.1 - 0.00015 22.3 26.1 0.00041 20.9 26.1 1.7 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 PRP77319.1 - 0.00033 19.6 12.4 0.00033 19.6 12.4 2.6 2 1 1 3 3 3 1 Spc7 kinetochore protein DUF4472 PF14739.6 PRP77319.1 - 0.014 16.1 22.9 0.056 14.2 13.5 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) MutS_III PF05192.18 PRP77319.1 - 0.016 15.4 8.9 1.2 9.3 5.7 2.4 2 0 0 2 2 2 0 MutS domain III EzrA PF06160.12 PRP77319.1 - 0.033 12.4 23.7 0.072 11.3 18.9 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DEAD PF00270.29 PRP77319.1 - 0.036 13.8 2.1 0.045 13.5 0.0 2.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase TMF_TATA_bd PF12325.8 PRP77319.1 - 0.044 14.0 30.1 0.61 10.3 12.3 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4404 PF14357.6 PRP77319.1 - 0.076 13.7 21.6 0.2 12.3 9.5 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Macoilin PF09726.9 PRP77319.1 - 0.081 11.5 12.8 0.18 10.3 12.8 1.6 1 0 0 1 1 1 0 Macoilin family CDPS PF16715.5 PRP77319.1 - 0.092 12.4 9.1 0.058 13.0 6.5 1.9 1 1 1 2 2 2 0 Cyclodipeptide synthase V_ATPase_I PF01496.19 PRP77319.1 - 0.11 10.4 14.0 0.19 9.6 14.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 PRP77319.1 - 0.15 12.4 21.6 11 6.5 0.0 3.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 PRP77319.1 - 0.32 8.9 11.3 0.12 10.3 8.0 1.8 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 PRP77319.1 - 0.41 10.7 12.6 2.1 8.4 4.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4201 PF13870.6 PRP77319.1 - 0.81 9.4 29.6 0.057 13.2 8.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) AAA_11 PF13086.6 PRP77319.1 - 0.96 9.2 9.9 2 8.1 9.9 1.6 1 0 0 1 1 1 0 AAA domain Taxilin PF09728.9 PRP77319.1 - 0.98 8.5 31.0 0.014 14.6 22.0 2.2 2 0 0 2 2 2 0 Myosin-like coiled-coil protein Laminin_I PF06008.14 PRP77319.1 - 1.1 8.9 24.7 0.084 12.6 10.6 2.5 1 1 1 2 2 2 0 Laminin Domain I Fe-S_assembly PF04384.13 PRP77319.1 - 1.1 9.9 6.2 9.4 6.9 1.0 4.1 3 1 1 4 4 4 0 Iron-sulphur cluster assembly Allexi_40kDa PF05549.11 PRP77319.1 - 1.4 8.3 9.2 1.4 8.4 7.6 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein LMBR1 PF04791.16 PRP77319.1 - 1.6 7.6 11.8 2.4 7.0 11.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.11 PRP77319.1 - 2.3 8.7 20.8 0.056 13.9 5.2 3.8 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 PRP77319.1 - 3.9 7.3 25.9 0.036 13.8 4.1 4.1 3 1 1 4 4 4 0 Septum formation initiator FapA PF03961.13 PRP77319.1 - 6.7 5.2 23.2 3.5 6.1 6.7 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A ATG16 PF08614.11 PRP77319.1 - 7.4 6.7 47.2 0.1 12.8 20.5 3.5 4 1 1 5 5 3 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 PRP77319.1 - 7.4 6.9 23.3 9.4 6.5 4.7 3.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FUSC PF04632.12 PRP77319.1 - 7.7 4.9 8.2 19 3.6 8.2 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family NPV_P10 PF05531.12 PRP77319.1 - 9.6 6.8 10.1 7 7.2 0.7 3.6 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 PRP77319.1 - 10 6.7 32.2 0.11 13.0 10.1 4.0 1 1 1 2 2 1 0 Cell division protein ZapB DHHC PF01529.20 PRP77320.1 - 3.9e-13 49.7 19.2 1.8e-10 41.0 5.3 3.1 2 1 1 3 3 3 2 DHHC palmitoyltransferase Sprouty PF05210.13 PRP77320.1 - 0.045 14.1 0.6 0.15 12.5 0.5 1.9 1 1 0 1 1 1 0 Sprouty protein (Spry) Fumerase_C PF05683.12 PRP77320.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Fumarase C-terminus Myb_DNA-binding PF00249.31 PRP77321.1 - 8.5e-44 147.5 12.4 9.6e-16 57.7 1.0 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP77321.1 - 6e-33 112.9 10.1 6.8e-17 61.5 0.5 3.8 2 1 2 4 4 4 3 Myb-like DNA-binding domain SLIDE PF09111.10 PRP77321.1 - 0.00057 19.9 0.3 1.3 9.1 0.0 3.6 3 1 1 4 4 4 2 SLIDE Rap1_C PF11626.8 PRP77321.1 - 0.018 15.1 4.7 0.16 12.1 0.6 2.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 PRP77321.1 - 0.025 14.8 0.2 20 5.5 0.0 3.6 3 0 0 3 3 3 0 Rap1 Myb domain YCII PF03795.14 PRP77322.1 - 0.00076 19.8 0.0 0.001 19.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain MutS_V PF00488.21 PRP77323.1 - 4.1e-81 271.5 0.1 9.5e-81 270.3 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PRP77323.1 - 6.1e-30 104.9 0.5 6.1e-30 104.9 0.5 2.3 2 0 0 2 2 2 1 MutS domain III Pkinase_Tyr PF07714.17 PRP77323.1 - 7.5e-24 84.4 0.8 1.6e-23 83.3 0.8 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP77323.1 - 4.4e-21 74.4 46.2 3.6e-06 26.6 3.8 6.5 2 1 4 7 7 7 6 Leucine rich repeat Pkinase PF00069.25 PRP77323.1 - 2.2e-14 53.4 0.7 4.8e-14 52.4 0.7 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP77323.1 - 1.6e-13 50.5 42.8 0.014 15.8 0.2 7.8 3 1 6 9 9 9 8 Leucine Rich repeats (2 copies) MutS_II PF05188.17 PRP77323.1 - 1.7e-12 47.8 0.0 4.8e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain II GPS PF01825.21 PRP77323.1 - 5.7e-07 30.0 0.3 1.7e-06 28.5 0.3 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif MutS_IV PF05190.18 PRP77323.1 - 2.9e-05 24.3 0.3 0.0001 22.6 0.3 2.0 1 0 0 1 1 1 1 MutS family domain IV SCAB_CC PF16712.5 PRP77323.1 - 0.00056 19.8 0.2 0.00056 19.8 0.2 2.4 3 0 0 3 3 3 1 Coiled-coil regions of plant-specific actin-binding protein DUF148 PF02520.17 PRP77323.1 - 2 8.5 6.3 3.3 7.9 0.6 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF148 Cadherin_3 PF16184.5 PRP77324.1 - 1.8e-07 31.2 1.7 0.00092 19.2 0.0 3.7 4 0 0 4 4 4 2 Cadherin-like Pkinase PF00069.25 PRP77325.1 - 1.7e-49 168.6 0.0 2.8e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77325.1 - 2.2e-49 168.1 0.0 3.7e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 PRP77325.1 - 1.7e-27 95.8 0.5 9.5e-13 48.5 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) DEP PF00610.21 PRP77325.1 - 2.6e-21 75.4 0.0 8e-21 73.9 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ank_4 PF13637.6 PRP77325.1 - 3e-21 75.5 1.1 0.00018 22.0 0.1 6.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP77325.1 - 1.1e-20 73.1 0.0 0.00011 22.5 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 PRP77325.1 - 6.5e-19 66.1 0.5 0.00057 20.1 0.0 7.2 7 0 0 7 7 6 3 Ankyrin repeat Ank_5 PF13857.6 PRP77325.1 - 7.9e-15 54.7 0.6 8.9e-07 29.1 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 PRP77325.1 - 1.3e-06 28.7 0.3 3.2e-06 27.5 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP77325.1 - 7.1e-05 22.8 0.1 0.00018 21.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 PRP77325.1 - 0.11 11.5 0.7 0.32 9.9 0.1 2.0 3 0 0 3 3 3 0 Haspin like kinase domain RasGEF PF00617.19 PRP77326.1 - 2.2e-49 168.0 4.5 4.4e-49 167.1 4.5 1.5 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.29 PRP77326.1 - 3e-23 81.7 0.2 3.3e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF_N PF00618.20 PRP77326.1 - 1.2e-15 57.6 0.0 5.5e-15 55.5 0.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif C2 PF00168.30 PRP77326.1 - 3e-14 53.1 0.1 6.7e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 C2 domain GRAM PF02893.20 PRP77326.1 - 5.1e-06 26.3 0.8 1.4e-05 25.0 0.8 1.7 1 0 0 1 1 1 1 GRAM domain Hemocyanin_N PF03722.14 PRP77326.1 - 0.0079 16.7 0.0 0.24 11.9 0.0 2.6 2 0 0 2 2 2 1 Hemocyanin, all-alpha domain CBFD_NFYB_HMF PF00808.23 PRP77327.1 - 4.4e-15 55.7 0.0 7.8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PRP77327.1 - 0.031 14.7 1.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF4750 PF15938.5 PRP77328.1 - 2.2e-10 40.0 0.2 2.6e-10 39.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) Herpes_glycop PF01528.16 PRP77328.1 - 0.28 10.0 3.9 0.34 9.7 3.9 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Met_gamma_lyase PF06838.11 PRP77329.1 - 0.0094 14.5 0.1 0.014 13.9 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Gag_MA PF01140.19 PRP77329.1 - 0.02 14.6 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 Matrix protein (MA), p15 UbiA PF01040.18 PRP77329.1 - 0.28 10.4 3.8 0.19 11.0 1.9 1.6 2 0 0 2 2 2 0 UbiA prenyltransferase family TLD PF07534.16 PRP77332.1 - 1.2e-25 90.4 0.1 2e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 PRP77332.1 - 9.7e-07 28.6 4.5 1.2e-05 25.1 4.5 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain AAA_29 PF13555.6 PRP77332.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hist_deacetyl PF00850.19 PRP77333.1 - 2.5e-83 280.1 0.1 2.5e-83 280.1 0.1 1.6 2 0 0 2 2 2 1 Histone deacetylase domain DnaJ_C PF01556.18 PRP77334.1 - 3.2e-34 118.2 0.0 4.8e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PRP77334.1 - 3.5e-20 71.9 2.2 6.4e-20 71.0 2.2 1.5 1 0 0 1 1 1 1 DnaJ domain Homeodomain PF00046.29 PRP77334.1 - 2.1e-06 27.4 1.6 3.7e-06 26.7 0.4 2.0 2 0 0 2 2 2 1 Homeodomain DnaJ_CXXCXGXG PF00684.19 PRP77334.1 - 0.00019 21.7 12.8 0.00053 20.3 12.8 1.8 1 0 0 1 1 1 1 DnaJ central domain DUF1543 PF07566.12 PRP77334.1 - 0.1 12.3 0.1 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) LEA_6 PF10714.9 PRP77334.1 - 0.2 11.8 3.5 0.33 11.0 1.1 2.4 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Lar_restr_allev PF14354.6 PRP77334.1 - 1.5 9.3 5.3 6.8 7.1 0.1 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar Anti-TRAP PF15777.5 PRP77334.1 - 6.8 6.7 20.7 0.85 9.6 6.4 3.8 4 1 1 5 5 5 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2401 PF10287.9 PRP77336.1 - 1.2e-53 182.1 2.1 2e-53 181.3 2.1 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 PRP77336.1 - 2.8e-15 56.5 0.0 2.8e-15 56.5 0.0 2.4 3 0 0 3 3 3 1 Glycine-rich protein domain (DUF2403) Phosducin PF02114.16 PRP77337.1 - 6.7e-14 51.5 0.1 9e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 PRP77337.1 - 8.9e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF1908 PF08926.11 PRP77337.1 - 0.021 13.9 1.3 1.8 7.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1908) AhpC-TSA PF00578.21 PRP77337.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 PRP77337.1 - 0.13 12.6 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 PRP77337.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Ccdc124 PF06244.12 PRP77337.1 - 0.35 11.4 4.0 4.6 7.8 2.4 2.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 Atg14 PF10186.9 PRP77338.1 - 0.072 12.2 11.4 0.11 11.5 11.3 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 PRP77338.1 - 0.12 12.8 14.6 0.091 13.1 5.4 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4240 PF14024.6 PRP77338.1 - 0.28 11.4 2.3 0.3 11.3 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4240) SEFIR PF08357.11 PRP77338.1 - 0.29 11.4 4.2 0.31 11.3 3.0 1.8 1 1 0 1 1 1 0 SEFIR domain NPV_P10 PF05531.12 PRP77338.1 - 0.34 11.4 3.4 35 5.0 0.2 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 PRP77338.1 - 0.52 9.6 11.5 1.2 8.4 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 PRP77338.1 - 1 9.2 6.5 3 7.7 0.0 3.3 2 1 0 3 3 3 0 Septum formation initiator SlyX PF04102.12 PRP77338.1 - 3.7 8.2 9.2 16 6.2 1.8 3.4 2 1 1 3 3 3 0 SlyX Med9 PF07544.13 PRP77338.1 - 7.3 6.8 11.5 1.6 8.8 1.9 3.2 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 APG6_N PF17675.1 PRP77338.1 - 9.9 6.7 18.7 13 6.3 10.2 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region UCH PF00443.29 PRP77339.1 - 9.9e-48 162.9 3.3 9.9e-48 162.9 3.3 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PLDc_2 PF13091.6 PRP77339.1 - 3.3e-28 98.2 0.2 6.8e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 PLD-like domain UCH_1 PF13423.6 PRP77339.1 - 3.3e-15 56.5 7.2 9.3e-10 38.6 1.9 3.4 3 1 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase SEC-C PF02810.15 PRP77339.1 - 4e-10 39.4 6.5 9.6e-10 38.2 6.5 1.7 1 0 0 1 1 1 1 SEC-C motif zf-MYND PF01753.18 PRP77339.1 - 2.8e-06 27.3 16.7 2.8e-06 27.3 16.7 2.6 2 0 0 2 2 2 1 MYND finger FAM83 PF07894.12 PRP77339.1 - 0.00084 19.0 0.1 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 FAM83 A-H PLDc PF00614.22 PRP77339.1 - 0.0023 18.1 0.1 0.0063 16.6 0.1 1.8 1 0 0 1 1 1 1 Phospholipase D Active site motif CPSase_L_D2 PF02786.17 PRP77340.1 - 5.7e-78 261.2 0.0 9.7e-78 260.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PRP77340.1 - 1e-45 154.8 0.5 2.8e-44 150.2 0.2 2.3 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PRP77340.1 - 3.9e-38 129.9 0.0 8.4e-38 128.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PRP77340.1 - 2.7e-15 56.0 2.2 4.5e-15 55.2 0.7 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PRP77340.1 - 1.4e-12 47.6 0.0 3.4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PRP77340.1 - 3.1e-08 33.4 0.0 6.4e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 PRP77340.1 - 5.7e-06 27.0 0.0 0.029 15.1 0.0 3.8 3 0 0 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 PRP77340.1 - 1.2e-05 25.0 0.3 0.056 13.3 0.0 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 PRP77340.1 - 5e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 PRP77340.1 - 0.00025 20.9 0.2 0.0022 17.9 0.0 2.4 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 PRP77340.1 - 0.0012 18.1 0.0 0.81 8.9 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion RimK PF08443.11 PRP77340.1 - 0.0023 17.5 0.0 0.01 15.5 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.19 PRP77340.1 - 0.0026 17.6 0.1 0.006 16.5 0.1 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein GARS_A PF01071.19 PRP77340.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 PRP77340.1 - 0.031 13.7 0.1 0.062 12.7 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.9 PRP77340.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF3182 PF11379.8 PRP77340.1 - 0.088 11.7 0.0 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3182) Methyltransf_23 PF13489.6 PRP77342.1 - 1.7e-09 37.7 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP77342.1 - 1e-08 35.8 0.0 2.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP77342.1 - 1.7e-07 31.8 0.0 4.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP77342.1 - 7e-06 26.7 0.0 1.6e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP77342.1 - 5.1e-05 23.1 0.0 8.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 PRP77342.1 - 0.013 14.9 0.0 0.035 13.5 0.0 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB UCH PF00443.29 PRP77343.1 - 1.3e-20 73.9 0.0 2.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_25 PF13649.6 PRP77343.1 - 2.2e-07 31.5 0.0 7.1e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain UCH_1 PF13423.6 PRP77343.1 - 5.4e-07 29.5 2.4 3e-06 27.0 2.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Methyltransf_23 PF13489.6 PRP77343.1 - 1.1e-06 28.6 0.0 2.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP77343.1 - 4.8e-05 24.0 0.0 0.00015 22.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP77343.1 - 0.00037 20.3 0.0 0.00082 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF1361 PF07099.11 PRP77343.1 - 0.0059 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1361) Pepdidase_M14_N PF18027.1 PRP77343.1 - 0.093 13.1 0.3 0.69 10.3 0.0 2.6 2 0 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain RNase_PH PF01138.21 PRP77344.1 - 1e-24 87.5 0.0 2e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PRP77344.1 - 7.4e-05 22.7 0.0 0.00034 20.6 0.0 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 CAP PF00188.26 PRP77346.1 - 1.4e-22 80.8 5.5 2e-22 80.4 5.5 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Nitroreductase PF00881.24 PRP77346.1 - 0.14 12.2 0.1 1.6 8.7 0.0 2.1 1 1 1 2 2 2 0 Nitroreductase family LIM PF00412.22 PRP77348.1 - 3e-24 85.0 20.6 4.4e-12 46.0 3.9 3.3 3 0 0 3 3 3 3 LIM domain Borrelia_P83 PF05262.11 PRP77348.1 - 6.8 5.1 15.8 9.1 4.6 15.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase_Tyr PF07714.17 PRP77349.1 - 8.2e-42 143.3 0.0 5.3e-40 137.3 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77349.1 - 5.3e-34 117.8 0.0 6.3e-32 111.0 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain COR PF16095.5 PRP77349.1 - 3.2e-30 105.4 0.1 8.3e-30 104.1 0.1 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 PRP77349.1 - 4.4e-21 75.3 0.1 9.3e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 PRP77349.1 - 1e-18 66.8 14.6 1.1e-08 34.6 0.7 4.2 2 1 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 PRP77349.1 - 1.6e-18 66.5 15.8 8.3e-07 29.2 1.3 5.4 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) Ras PF00071.22 PRP77349.1 - 1.8e-10 40.6 0.1 4.6e-10 39.3 0.1 1.7 1 1 0 1 1 1 1 Ras family Arf PF00025.21 PRP77349.1 - 0.00056 19.4 0.2 0.0017 17.8 0.2 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family LRR_9 PF14580.6 PRP77349.1 - 0.0025 17.3 4.4 0.52 9.8 0.9 2.5 1 1 0 2 2 2 2 Leucine-rich repeat PduV-EutP PF10662.9 PRP77349.1 - 0.012 15.3 1.5 1.4 8.7 0.2 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 PRP77349.1 - 0.014 15.4 0.1 0.085 12.9 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase LRR_1 PF00560.33 PRP77349.1 - 0.15 12.7 13.2 38 5.4 0.1 6.3 6 1 0 6 6 5 0 Leucine Rich Repeat Sugar_tr PF00083.24 PRP77350.1 - 4.8e-45 154.2 27.1 8.3e-27 94.1 7.0 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 PRP77350.1 - 3.1e-22 79.0 56.3 7.3e-21 74.5 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CH PF00307.31 PRP77350.1 - 1.3e-11 44.6 2.7 1.2e-09 38.2 0.1 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP77350.1 - 0.02 14.8 0.0 0.062 13.1 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain Rer1 PF03248.13 PRP77350.1 - 0.15 11.7 0.1 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Rer1 family UCH PF00443.29 PRP77351.1 - 8e-07 28.8 0.0 8.4e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3430 PF11912.8 PRP77351.1 - 7e-05 23.0 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) UCH_1 PF13423.6 PRP77351.1 - 0.039 13.5 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PAS_9 PF13426.7 PRP77353.1 - 6.7e-13 48.8 0.0 1.4e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 PAS domain GAF PF01590.26 PRP77353.1 - 2.5e-06 28.2 0.0 6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 GAF domain PAS PF00989.25 PRP77353.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold GAF_2 PF13185.6 PRP77353.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 GAF domain PAS_8 PF13188.7 PRP77353.1 - 0.034 14.2 0.0 0.093 12.8 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS_7 PF12860.7 PRP77353.1 - 0.096 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold GAF_3 PF13492.6 PRP77353.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 GAF domain PAS_9 PF13426.7 PRP77354.1 - 3.4e-09 36.9 1.3 6.8e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 PAS domain zf-RING_2 PF13639.6 PRP77354.1 - 1.2e-08 35.2 6.2 2.6e-08 34.1 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PRP77354.1 - 1e-07 32.1 3.2 2.7e-07 30.7 3.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PRP77354.1 - 2e-07 30.7 4.5 4.7e-07 29.6 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GAF PF01590.26 PRP77354.1 - 7.5e-07 29.8 0.0 1.9e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 GAF domain PAS PF00989.25 PRP77354.1 - 2.3e-06 27.6 0.0 2.3e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 PAS fold zf-C3HC4_2 PF13923.6 PRP77354.1 - 5.3e-06 26.2 5.7 1.2e-05 25.0 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP77354.1 - 1.6e-05 24.7 3.5 3e-05 23.8 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PRP77354.1 - 0.00042 19.9 2.4 0.00088 18.9 2.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PRP77354.1 - 0.0009 19.2 3.6 0.0009 19.2 3.6 2.1 2 0 0 2 2 1 1 RING-type zinc-finger UIM PF02809.20 PRP77354.1 - 0.0022 17.8 4.2 0.007 16.2 4.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif zf-RING_11 PF17123.5 PRP77354.1 - 0.0072 16.0 2.4 0.019 14.7 2.4 1.8 1 0 0 1 1 1 1 RING-like zinc finger GAF_2 PF13185.6 PRP77354.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 2 0 0 2 2 1 0 GAF domain Prok-RING_4 PF14447.6 PRP77354.1 - 0.011 15.5 4.7 0.024 14.5 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP77354.1 - 0.037 14.0 4.6 0.089 12.8 4.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain PAS_4 PF08448.10 PRP77354.1 - 0.073 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold zf-C3HC4_4 PF15227.6 PRP77354.1 - 0.38 10.9 4.0 0.95 9.7 4.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DDHD PF02862.17 PRP77354.1 - 0.57 10.3 4.3 1.1 9.4 4.3 1.5 1 0 0 1 1 1 0 DDHD domain LicD PF04991.13 PRP77354.1 - 1.5 8.9 7.7 4 7.5 7.7 1.6 1 0 0 1 1 1 0 LicD family CDC45 PF02724.14 PRP77354.1 - 1.6 7.0 17.5 2.4 6.3 17.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 PRP77354.1 - 4.3 6.2 7.0 8 5.3 7.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Senescence PF06911.12 PRP77355.1 - 9.4e-26 91.2 5.1 1.6e-25 90.5 5.1 1.4 1 0 0 1 1 1 1 Senescence-associated protein Inp1 PF12634.7 PRP77355.1 - 9.8e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 MIT PF04212.18 PRP77355.1 - 0.00068 19.7 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain 2OG-FeII_Oxy_3 PF13640.6 PRP77356.1 - 3.3e-12 47.1 0.0 5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PRP77356.1 - 0.013 16.0 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 PRP77356.1 - 0.073 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Fmp27_WPPW PF10359.9 PRP77357.1 - 0.018 13.9 8.3 0.021 13.7 8.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Jnk-SapK_ap_N PF09744.9 PRP77357.1 - 0.054 13.7 16.2 0.071 13.3 16.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 PRP77357.1 - 0.064 13.6 18.0 0.13 12.7 17.1 1.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region CREPT PF16566.5 PRP77357.1 - 0.066 13.4 7.1 0.088 13.0 7.1 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour BLOC1_2 PF10046.9 PRP77357.1 - 0.074 13.4 8.4 0.11 12.8 8.4 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 PRP77357.1 - 0.11 12.8 10.4 0.15 12.4 10.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ECH_2 PF16113.5 PRP77357.1 - 0.13 11.7 4.2 0.16 11.4 4.2 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase FapA PF03961.13 PRP77357.1 - 0.17 10.4 5.1 0.19 10.3 5.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 PRP77357.1 - 0.21 11.2 7.2 0.24 10.9 7.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 PRP77357.1 - 0.29 11.6 16.2 0.51 10.9 16.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region NYD-SP28_assoc PF14775.6 PRP77357.1 - 0.38 10.9 7.6 9.2 6.5 0.2 2.6 1 1 1 2 2 2 0 Sperm tail C-terminal domain DUF3818 PF12825.7 PRP77357.1 - 0.45 9.5 7.7 0.53 9.2 7.7 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) FUSC PF04632.12 PRP77357.1 - 0.59 8.6 2.8 0.7 8.3 2.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 PRP77357.1 - 0.62 10.1 4.6 0.86 9.6 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 PRP77357.1 - 0.83 10.3 8.8 0.7 10.6 6.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) YabA PF06156.13 PRP77357.1 - 1 10.0 10.2 0.53 10.9 7.2 1.8 1 1 1 2 2 2 0 Initiation control protein YabA BORG_CEP PF14957.6 PRP77357.1 - 1.2 10.3 7.7 0.4 11.8 4.9 1.5 1 1 1 2 2 2 0 Cdc42 effector Glucan_synthase PF02364.15 PRP77357.1 - 1.6 6.8 4.1 1.9 6.5 4.1 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component DUF3450 PF11932.8 PRP77357.1 - 1.9 7.8 12.0 3.8 6.8 3.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 PRP77357.1 - 2.1 9.1 6.9 2.9 8.6 6.4 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 PRP77357.1 - 2.5 7.3 7.7 3 7.0 7.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein CENP-Q PF13094.6 PRP77357.1 - 2.7 8.2 18.4 6.1 7.0 18.4 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-H PF05837.12 PRP77357.1 - 4.2 7.8 13.2 0.69 10.3 8.8 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 PRP77357.1 - 4.5 5.1 9.8 5.2 4.9 9.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 PRP77357.1 - 4.9 6.4 8.6 1.6 8.0 5.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DPPIV_N PF00930.21 PRP77358.1 - 2.9e-70 236.8 9.6 2.9e-70 236.8 9.6 1.4 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 PRP77358.1 - 3.5e-45 154.1 0.2 6.8e-45 153.2 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PRP77358.1 - 0.0031 16.8 0.2 0.29 10.4 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 PRP77358.1 - 0.0036 16.9 0.4 0.12 11.9 0.1 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 PRP77358.1 - 0.0042 17.7 0.0 0.016 15.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 PRP77358.1 - 0.0048 16.6 0.4 0.038 13.6 0.5 2.2 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 PRP77358.1 - 0.0049 16.5 0.2 0.035 13.6 0.2 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 PRP77358.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 PRP77358.1 - 0.029 14.0 0.0 0.083 12.5 0.0 1.8 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 PRP77358.1 - 0.065 13.2 0.0 0.28 11.1 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2920 PF11144.8 PRP77358.1 - 0.1 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PEX11 PF05648.14 PRP77359.1 - 9.1e-21 74.3 0.4 1.2e-20 73.9 0.4 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Csm1_B PF18211.1 PRP77359.1 - 0.078 12.8 0.3 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Csm1 subunit domain B Ribosomal_L33 PF00471.20 PRP77360.1 - 2e-08 34.6 0.2 2.3e-08 34.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Methyltransf_14 PF08484.11 PRP77360.1 - 0.0005 19.9 0.0 0.00062 19.6 0.0 1.0 1 0 0 1 1 1 1 C-methyltransferase C-terminal domain Glyco_hydro_cc PF11790.8 PRP77362.1 - 8.2e-49 166.3 0.1 1.2e-48 165.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PAN_4 PF14295.6 PRP77362.1 - 2.3e-26 91.4 27.3 3.7e-09 36.4 2.3 4.8 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 PRP77362.1 - 1.1e-08 35.0 23.8 0.00068 19.7 0.8 4.9 5 0 0 5 5 5 4 PAN-like domain PAN_1 PF00024.26 PRP77362.1 - 3.4e-05 23.7 15.8 0.22 11.5 0.3 4.4 4 0 0 4 4 4 3 PAN domain GTA_TIM PF13547.6 PRP77362.1 - 0.0038 16.6 0.2 0.0063 15.8 0.2 1.2 1 0 0 1 1 1 1 GTA TIM-barrel-like domain ATP-synt_E PF05680.12 PRP77362.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase E chain RRM_1 PF00076.22 PRP77363.1 - 0.0073 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IP_trans PF02121.18 PRP77364.1 - 2.2e-89 299.3 0.1 2.2e-89 299.3 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol transfer protein PRELI PF04707.14 PRP77364.1 - 0.0078 16.0 0.2 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 PRELI-like family OPT PF03169.15 PRP77365.1 - 4.2e-91 306.4 40.3 4.8e-91 306.3 40.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TMEM125 PF15109.6 PRP77365.1 - 0.085 13.2 1.3 2.2 8.6 0.2 2.6 2 0 0 2 2 2 0 TMEM125 protein family DUF1453 PF07301.11 PRP77365.1 - 0.42 10.6 4.8 0.18 11.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1453) PPC PF04151.15 PRP77366.1 - 0.23 12.6 5.7 3.3 8.9 2.4 3.6 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Chromo PF00385.24 PRP77367.1 - 1.1e-13 50.9 0.0 1.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP77367.1 - 0.02 15.0 0.5 0.039 14.1 0.5 1.6 1 1 0 1 1 1 0 Polycomb-like MTF2 factor 2 Myosin_TH1 PF06017.13 PRP77368.1 - 1.1e-38 132.8 2.1 1.3e-38 132.6 2.1 1.1 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 PRP77368.1 - 0.00018 21.0 2.6 0.00018 21.0 2.6 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif DUF4743 PF15916.5 PRP77368.1 - 0.0055 16.7 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) Ints3 PF10189.9 PRP77369.1 - 0.19 10.9 0.1 0.19 10.9 0.1 1.5 2 0 0 2 2 2 0 Integrator complex subunit 3 Rax2 PF12768.7 PRP77370.1 - 0.0017 17.8 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DHHC PF01529.20 PRP77370.1 - 0.019 15.1 0.2 0.031 14.4 0.2 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase P2X_receptor PF00864.19 PRP77373.1 - 1.3e-82 277.8 0.3 2.3e-82 277.0 0.3 1.4 1 1 0 1 1 1 1 ATP P2X receptor BBP1_C PF15272.6 PRP77373.1 - 0.023 14.5 1.0 0.044 13.6 1.0 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF1356 PF07092.12 PRP77374.1 - 3.8e-07 29.6 3.1 3.8e-07 29.6 2.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 PRP77374.1 - 1.6e-05 25.4 0.5 4.2e-05 24.0 0.5 1.7 1 1 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 PRP77375.1 - 4.8e-12 45.7 0.5 1e-11 44.5 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) DUF3712 PF12505.8 PRP77375.1 - 0.0077 16.5 1.2 0.19 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) CDP-OH_P_transf PF01066.21 PRP77375.1 - 0.076 13.8 0.5 0.076 13.8 0.5 3.9 3 3 0 3 3 3 0 CDP-alcohol phosphatidyltransferase dCMP_cyt_deam_1 PF00383.23 PRP77376.1 - 2.3e-26 91.6 0.0 2.7e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PRP77376.1 - 7.2e-12 45.2 0.0 9.5e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 PRP77376.1 - 0.13 12.3 0.2 0.42 10.7 0.1 1.8 1 1 1 2 2 2 0 APOBEC3 Cellulase PF00150.18 PRP77377.1 - 1.1e-46 159.5 1.4 2.1e-46 158.7 1.4 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 PRP77377.1 - 2.5e-09 36.9 8.8 2.5e-09 36.9 8.8 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF3510 PF12022.8 PRP77377.1 - 0.25 11.8 1.5 0.8 10.1 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DNase_II PF03265.15 PRP77379.1 - 1.8e-87 293.6 0.1 2.3e-87 293.3 0.1 1.1 1 0 0 1 1 1 1 Deoxyribonuclease II RPW8 PF05659.11 PRP77380.1 - 0.25 11.0 4.6 1.1 9.0 1.1 3.0 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 UvrD_C PF13361.6 PRP77380.1 - 3.5 6.9 10.8 2.3 7.5 7.4 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Glyco_hydro_72 PF03198.14 PRP77382.1 - 1.2e-107 359.8 1.7 2e-107 359.1 1.7 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 PRP77382.1 - 1.1e-25 90.1 17.7 5.7e-15 55.8 7.7 2.8 2 0 0 2 2 2 2 X8 domain Glyco_hydro_2_C PF02836.17 PRP77382.1 - 1e-06 28.1 0.2 2.3e-06 26.9 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 PRP77382.1 - 0.00019 20.9 0.3 0.00059 19.3 0.3 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3334 PF11813.8 PRP77383.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Mago-bind PF09282.10 PRP77384.1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Mago binding VIT PF08487.10 PRP77386.1 - 0.45 10.7 2.0 0.94 9.7 2.0 1.6 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain MIP-T3 PF10243.9 PRP77387.1 - 2.1e-42 143.7 0.1 5.9e-42 142.2 0.1 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 PRP77387.1 - 1.7e-34 119.0 14.3 1.7e-34 119.0 14.3 2.8 2 1 0 2 2 1 1 Microtubule-binding protein MIP-T3 C-terminal region DUF948 PF06103.11 PRP77387.1 - 0.0053 17.0 0.3 0.028 14.7 0.1 2.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Macoilin PF09726.9 PRP77387.1 - 0.052 12.1 19.5 0.12 10.9 19.5 1.6 1 0 0 1 1 1 0 Macoilin family DnaB_bind PF10410.9 PRP77387.1 - 0.054 13.7 0.1 15 5.8 0.0 3.0 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Syntaxin-6_N PF09177.11 PRP77387.1 - 0.96 10.0 7.7 1.5 9.4 4.5 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal PIN_4 PF13638.6 PRP77387.1 - 1.5 9.1 6.4 0.44 10.8 2.3 2.3 2 0 0 2 2 2 0 PIN domain YabA PF06156.13 PRP77387.1 - 1.7 9.4 8.1 19 5.9 2.7 3.3 1 1 1 2 2 2 0 Initiation control protein YabA Lectin_N PF03954.14 PRP77387.1 - 1.8 8.3 4.5 7.3 6.4 4.5 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Tup_N PF08581.10 PRP77387.1 - 1.9 8.9 13.1 2 8.8 4.6 3.8 3 0 0 3 3 3 0 Tup N-terminal DUF1664 PF07889.12 PRP77387.1 - 3.6 7.6 10.3 2.9 7.9 3.0 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 PRP77387.1 - 8.2 6.6 17.2 0.81 9.9 8.6 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Arf PF00025.21 PRP77388.1 - 9.1e-61 204.3 0.0 1.4e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PRP77388.1 - 5.1e-12 45.6 0.0 8.9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PRP77388.1 - 1.2e-11 44.9 0.0 3.9e-11 43.2 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PRP77388.1 - 1.9e-09 37.2 2.8 2.3e-06 27.0 0.2 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.22 PRP77388.1 - 4.5e-09 36.1 0.0 8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 PRP77388.1 - 2.9e-08 33.4 0.0 4.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP77388.1 - 0.0016 18.5 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 PRP77388.1 - 0.11 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF4955 PF16315.5 PRP77389.1 - 1.6e-05 25.2 0.0 3.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4955) Exo_endo_phos PF03372.23 PRP77390.1 - 5.7e-13 48.9 0.0 9.9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PWI PF01480.17 PRP77391.1 - 8.2e-15 54.9 0.6 2.1e-14 53.6 0.6 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 PRP77391.1 - 3.6e-09 36.3 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC53 PF10152.9 PRP77391.1 - 5.9 7.3 12.1 0.093 13.1 1.0 2.5 1 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Pkinase PF00069.25 PRP77392.1 - 5.2e-67 226.0 0.0 6.2e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77392.1 - 2.4e-32 112.3 0.0 3e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP77392.1 - 5.4e-05 22.6 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP77392.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP77392.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_M24 PF00557.24 PRP77393.1 - 2.4e-42 145.0 0.0 2.9e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PLAC8 PF04749.17 PRP77394.1 - 4.3e-15 56.5 23.2 4.3e-15 56.5 23.2 1.8 2 0 0 2 2 2 1 PLAC8 family BLUF PF04940.12 PRP77394.1 - 0.0025 17.9 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Sensors of blue-light using FAD DNA_pol_E_B PF04042.16 PRP77394.1 - 0.073 12.4 0.1 1.2 8.4 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase alpha/epsilon subunit B Pkinase_Tyr PF07714.17 PRP77395.1 - 1.2e-46 159.1 0.0 1.8e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77395.1 - 1e-44 152.9 0.0 1.9e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Exo_endo_phos PF03372.23 PRP77395.1 - 1e-18 67.7 0.1 1.8e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PH PF00169.29 PRP77395.1 - 4.5e-14 52.8 0.0 1.2e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 PRP77395.1 - 8.5e-13 48.2 0.2 3e-12 46.5 0.1 2.1 2 0 0 2 2 2 1 SH2 domain PH_11 PF15413.6 PRP77395.1 - 0.0011 19.4 0.5 0.18 12.3 0.1 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain SH2_2 PF14633.6 PRP77395.1 - 0.0028 17.1 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 SH2 domain SMN PF06003.12 PRP77395.1 - 0.025 13.8 0.2 0.045 13.0 0.2 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SSXT PF05030.12 PRP77396.1 - 1.6e-18 66.1 1.6 5e-18 64.5 1.3 2.1 2 0 0 2 2 2 1 SSXT protein (N-terminal region) Myb_DNA-binding PF00249.31 PRP77396.1 - 2.2e-05 24.5 0.0 4.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TetR_C_11 PF16859.5 PRP77396.1 - 0.067 13.5 0.6 0.14 12.5 0.6 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain APG6_N PF17675.1 PRP77396.1 - 0.12 12.9 15.8 0.12 13.0 1.6 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4168 PF13767.6 PRP77396.1 - 1.8 9.8 10.6 11 7.3 6.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Golgin_A5 PF09787.9 PRP77396.1 - 3.3 7.1 17.4 5.5 6.4 17.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 PRP77396.1 - 3.4 6.7 9.1 7.1 5.6 9.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ank_2 PF12796.7 PRP77399.1 - 6e-28 97.3 0.0 5.5e-08 33.3 0.0 6.1 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77399.1 - 1.5e-24 86.0 1.4 3.5e-06 27.4 0.0 8.7 5 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77399.1 - 1.6e-17 61.8 0.4 2.2 9.1 0.0 10.3 10 2 1 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 PRP77399.1 - 5.9e-12 45.6 2.6 2 8.8 0.2 8.7 6 2 2 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP77399.1 - 3.8e-11 42.9 7.8 7 7.3 0.0 9.5 9 2 1 10 10 10 2 Ankyrin repeat Hairy_orange PF07527.13 PRP77399.1 - 0.011 16.0 4.3 96 3.3 0.0 6.8 7 0 0 7 7 7 0 Hairy Orange HTH_13 PF11972.8 PRP77399.1 - 3.4 7.8 5.9 14 5.8 0.3 4.2 4 1 0 4 4 4 0 HTH DNA binding domain MCPVI PF02993.14 PRP77400.1 - 0.0085 15.9 0.1 0.0098 15.7 0.1 1.1 1 0 0 1 1 1 1 Minor capsid protein VI GPS PF01825.21 PRP77401.1 - 3.9e-11 43.3 7.5 1.2e-10 41.7 7.5 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP77401.1 - 1.6e-08 34.1 1.1 2.8e-07 30.1 0.8 2.5 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77401.1 - 3.6e-07 29.8 1.3 3.3e-06 26.7 1.3 2.1 1 1 0 1 1 1 1 Protein kinase domain DUF3827 PF12877.7 PRP77401.1 - 0.0013 17.2 1.5 0.0013 17.2 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3827) LRR19-TM PF15176.6 PRP77401.1 - 0.0024 17.8 0.4 0.0054 16.7 0.4 1.5 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain Alpha_kinase PF02816.18 PRP77401.1 - 0.04 14.0 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha-kinase family Collectrin PF16959.5 PRP77401.1 - 0.043 13.6 1.6 0.084 12.6 1.6 1.4 1 0 0 1 1 1 0 Renal amino acid transporter SOG2 PF10428.9 PRP77401.1 - 0.085 12.0 11.9 0.13 11.4 11.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein EphA2_TM PF14575.6 PRP77401.1 - 0.2 12.6 1.3 0.5 11.3 1.3 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Synaptobrevin PF00957.21 PRP77401.1 - 0.22 11.3 2.0 0.5 10.2 2.0 1.6 1 0 0 1 1 1 0 Synaptobrevin Nucleoporin_FG2 PF15967.5 PRP77401.1 - 0.29 9.6 12.5 0.44 9.0 12.5 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region Insulin_TMD PF17870.1 PRP77401.1 - 0.39 10.8 6.1 0.84 9.7 6.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Shisa PF13908.6 PRP77401.1 - 0.49 10.6 16.4 0.14 12.4 1.8 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator RIFIN PF02009.16 PRP77401.1 - 0.77 9.6 8.6 0.062 13.2 0.4 2.1 2 0 0 2 2 2 0 Rifin Orf78 PF06024.12 PRP77401.1 - 0.81 10.0 3.9 0.46 10.8 1.1 2.0 2 0 0 2 2 2 0 Orf78 (ac78) F-box-like PF12937.7 PRP77402.1 - 2.3e-10 40.2 1.2 6.4e-10 38.8 1.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP77402.1 - 3.3e-07 30.0 0.5 1.2e-06 28.2 0.5 2.1 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 PRP77402.1 - 3.5e-05 23.5 2.7 0.22 11.7 0.0 4.6 6 0 0 6 6 3 2 Leucine Rich repeat DUF3450 PF11932.8 PRP77402.1 - 8.8e-05 21.9 0.8 0.00015 21.2 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 PRP77402.1 - 0.0044 17.0 0.8 0.011 15.8 0.8 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Takusan PF04822.13 PRP77402.1 - 0.006 16.5 0.7 0.018 14.9 0.7 1.8 1 0 0 1 1 1 1 Takusan YabA PF06156.13 PRP77402.1 - 0.013 16.1 2.4 0.013 16.1 0.5 1.9 2 0 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 PRP77402.1 - 0.014 15.8 1.2 0.044 14.2 1.2 1.8 1 0 0 1 1 1 0 Cell division protein ZapB TRPM_tetra PF16519.5 PRP77402.1 - 0.016 15.3 2.5 0.055 13.6 2.5 2.0 1 0 0 1 1 1 0 Tetramerisation domain of TRPM FAM184 PF15665.5 PRP77402.1 - 0.017 14.9 0.8 3.9 7.2 0.2 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B PdxJ PF03740.13 PRP77402.1 - 0.029 13.5 0.1 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ NPV_P10 PF05531.12 PRP77402.1 - 0.04 14.4 0.6 0.13 12.7 0.6 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 PRP77402.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 PRP77402.1 - 0.15 12.4 4.1 0.2 12.0 1.3 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 PRP77402.1 - 0.2 11.9 3.2 0.65 10.2 3.2 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LRR_4 PF12799.7 PRP77402.1 - 0.29 11.6 6.9 4.5 7.8 0.0 5.1 4 1 2 6 6 5 0 Leucine Rich repeats (2 copies) DUF1664 PF07889.12 PRP77402.1 - 0.55 10.3 3.1 1.1 9.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IFT20 PF14931.6 PRP77402.1 - 1.1 9.5 4.9 1.4 9.1 2.2 2.4 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 HA PF03457.14 PRP77403.1 - 1.4e-08 34.9 1.9 1.4e-08 34.9 1.9 2.1 2 0 0 2 2 2 1 Helicase associated domain DUF1409 PF07197.12 PRP77403.1 - 0.029 14.2 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) Adaptin_N PF01602.20 PRP77404.1 - 3.3e-61 207.5 11.1 3.3e-60 204.1 4.8 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 PRP77404.1 - 9e-08 32.3 8.5 2.8e-06 27.5 0.1 3.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 AP4E_app_platf PF14807.6 PRP77404.1 - 3e-05 24.3 0.0 0.0001 22.6 0.0 2.0 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform Coatomer_b_Cpla PF14806.6 PRP77404.1 - 0.0099 15.9 0.1 0.048 13.6 0.0 2.2 3 0 0 3 3 3 1 Coatomer beta subunit appendage platform B2-adapt-app_C PF09066.10 PRP77404.1 - 0.021 14.9 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain RhoGEF PF00621.20 PRP77405.1 - 4.2e-38 131.4 0.0 8.8e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF4149 PF13664.6 PRP77405.1 - 4.3e-19 68.7 1.8 4.3e-19 68.7 1.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) PH PF00169.29 PRP77405.1 - 0.00055 20.4 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 PRP77405.1 - 0.0064 16.3 2.1 0.4 10.5 2.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain Tmem26 PF09772.9 PRP77405.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 26 Rad51 PF08423.11 PRP77406.1 - 4.5e-44 150.6 0.2 5.9e-44 150.3 0.2 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PRP77406.1 - 2.4e-07 30.5 0.0 3.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PRP77406.1 - 8.4e-06 25.3 0.4 0.0021 17.4 0.0 2.4 2 0 0 2 2 2 2 KaiC DnaB_C PF03796.15 PRP77406.1 - 1.4e-05 24.5 1.9 0.001 18.5 0.8 2.1 1 1 1 2 2 2 2 DnaB-like helicase C terminal domain RecA PF00154.21 PRP77406.1 - 0.0013 18.3 0.9 0.0029 17.1 0.9 1.6 1 1 0 1 1 1 1 recA bacterial DNA recombination protein PBP PF01161.20 PRP77407.1 - 3.7e-19 69.3 0.1 5.6e-19 68.8 0.1 1.3 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein CHCH PF06747.13 PRP77408.1 - 7.4e-08 32.3 5.3 1.1e-07 31.8 5.3 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 PRP77408.1 - 0.00019 21.4 7.2 0.00026 20.9 7.0 1.4 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 PRP77408.1 - 0.00031 20.4 3.1 0.00038 20.1 3.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 PRP77408.1 - 0.0028 17.9 4.6 0.0045 17.3 4.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 PRP77408.1 - 0.092 13.1 5.5 0.15 12.5 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) tRNA-synt_2b PF00587.25 PRP77409.1 - 1.1e-32 113.4 0.0 2.6e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PRP77409.1 - 1e-06 29.0 6.4 8.7e-05 22.7 6.4 2.3 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF1963 PF09234.10 PRP77410.1 - 3.9e-12 47.1 0.0 5.9e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) EGF_2 PF07974.13 PRP77411.1 - 2.6e-09 37.3 142.0 0.0091 16.3 5.1 9.0 7 1 1 8 8 8 6 EGF-like domain EGF_Tenascin PF18720.1 PRP77411.1 - 0.0071 16.4 9.3 0.0071 16.4 9.3 9.0 8 1 0 8 8 8 3 Tenascin EGF domain DAG1 PF05454.11 PRP77411.1 - 0.0074 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) HemY_N PF07219.13 PRP77411.1 - 0.041 14.1 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TMEM154 PF15102.6 PRP77411.1 - 0.13 12.1 0.1 0.39 10.6 0.1 1.8 1 0 0 1 1 1 0 TMEM154 protein family PMP1_2 PF08114.11 PRP77411.1 - 0.9 9.3 7.0 0.081 12.7 1.8 1.9 2 0 0 2 2 2 0 ATPase proteolipid family Orf78 PF06024.12 PRP77411.1 - 1.1 9.6 2.6 1.9 8.9 1.6 1.8 2 0 0 2 2 2 0 Orf78 (ac78) SapB_1 PF05184.15 PRP77414.1 - 1.3e-05 25.1 2.0 1.3e-05 25.1 2.0 3.2 4 0 0 4 4 4 1 Saposin-like type B, region 1 SapB_2 PF03489.17 PRP77414.1 - 0.0058 16.7 0.5 0.014 15.5 0.5 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 2 Pkinase PF00069.25 PRP77416.1 - 0.00095 18.6 0.0 0.00095 18.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kei1 PF08552.11 PRP77417.1 - 0.085 12.7 4.6 0.15 11.9 4.6 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Tetraspanin PF00335.20 PRP77417.1 - 0.72 9.5 6.8 1.4 8.5 7.0 1.3 1 1 0 1 1 1 0 Tetraspanin family DUF202 PF02656.15 PRP77417.1 - 6.8 7.2 9.9 24 5.5 6.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) His_Phos_1 PF00300.22 PRP77418.1 - 3e-39 134.7 0.1 3.8e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) p450 PF00067.22 PRP77419.1 - 3.6e-37 128.2 0.0 3.9e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAHP_synth_2 PF01474.16 PRP77420.1 - 8.8e-194 644.0 0.0 1e-193 643.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Myb_DNA-binding PF00249.31 PRP77421.1 - 2.3e-32 110.9 2.1 2e-16 59.9 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP77421.1 - 4.3e-25 87.7 2.7 7.4e-17 61.4 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 PRP77421.1 - 0.0068 16.4 0.0 1.2 9.2 0.0 2.7 1 1 1 2 2 2 1 SLIDE Rap1_C PF11626.8 PRP77421.1 - 0.021 14.9 1.4 0.22 11.6 1.6 2.4 1 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Lbh PF15317.6 PRP77421.1 - 0.053 14.4 1.1 0.15 12.9 0.2 2.2 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein Spore_III_AB PF09548.10 PRP77421.1 - 0.071 13.2 0.7 1.9 8.5 0.1 2.7 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_7 PF15963.5 PRP77421.1 - 0.13 12.1 3.0 4.1 7.4 0.0 3.7 3 1 1 4 4 4 0 Myb DNA-binding like CN_hydrolase PF00795.22 PRP77423.1 - 7.3e-57 192.7 0.0 8.4e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Mito_carr PF00153.27 PRP77424.1 - 6.2e-19 67.7 0.2 1.4e-08 34.6 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.7 PRP77425.1 - 2.1e-51 172.4 4.4 2.1e-13 50.7 0.2 5.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77425.1 - 9e-48 160.1 4.6 1.1e-11 45.0 0.6 9.0 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77425.1 - 3.5e-41 134.4 6.2 0.00075 19.8 0.0 11.5 12 0 0 12 12 12 10 Ankyrin repeat Ank PF00023.30 PRP77425.1 - 5.6e-36 121.4 13.5 0.00028 21.2 0.2 10.8 10 1 1 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 PRP77425.1 - 1.7e-34 117.4 3.6 2e-07 31.1 0.0 8.7 4 2 6 10 10 10 8 Ankyrin repeats (many copies) 30K_MP_core PF17644.1 PRP77425.1 - 0.011 15.6 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 Core domain of 30K viral movement proteins DUF249 PF03158.13 PRP77425.1 - 0.039 13.6 0.2 1.2 8.9 0.0 3.0 3 1 0 3 3 3 0 Multigene family 530 protein Acetyltransf_18 PF18014.1 PRP77426.1 - 1.8e-10 40.7 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP77426.1 - 8e-08 32.6 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP77426.1 - 4.3e-06 26.7 0.0 9.4e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP77426.1 - 1.2e-05 25.5 0.0 3.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 PRP77426.1 - 0.037 14.7 0.0 0.1 13.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain LRR_8 PF13855.6 PRP77427.1 - 6e-24 83.6 33.7 7.2e-08 32.1 2.7 5.3 2 1 5 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 PRP77427.1 - 5.8e-16 58.3 27.1 0.00017 21.9 0.2 5.7 4 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP77427.1 - 7.2e-07 28.9 22.1 0.68 10.7 0.1 9.1 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP77427.1 - 0.0013 18.6 24.6 1.2 9.4 0.7 7.4 8 0 0 8 8 8 2 Leucine Rich repeat Senescence PF06911.12 PRP77427.1 - 0.036 14.4 6.8 0.077 13.3 6.8 1.5 1 0 0 1 1 1 0 Senescence-associated protein Alpha-amylase PF00128.24 PRP77428.1 - 7.6e-115 384.0 1.1 1.1e-114 383.5 1.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 PRP77428.1 - 6.3e-09 35.8 0.0 2.1e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 PRP77428.1 - 0.0036 16.5 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 PRP77428.1 - 0.016 15.5 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.18 PRP77428.1 - 0.052 14.0 0.0 0.21 12.1 0.0 2.1 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Acetyltransf_1 PF00583.25 PRP77429.1 - 1.9e-11 44.2 0.0 2.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP77429.1 - 4.9e-10 39.4 0.0 6.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP77429.1 - 2.6e-06 27.7 0.0 3.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP77429.1 - 0.00015 22.0 0.0 0.00017 21.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP77429.1 - 0.052 13.6 0.0 0.25 11.4 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain C2 PF00168.30 PRP77430.1 - 1.9e-07 31.3 0.1 2.4e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 C2 domain MAPEG PF01124.18 PRP77431.1 - 2e-24 85.9 0.4 2.4e-24 85.7 0.4 1.1 1 0 0 1 1 1 1 MAPEG family RBP_receptor PF14752.6 PRP77433.1 - 1.3e-19 70.3 20.0 7.3e-19 67.8 20.0 1.9 1 1 0 1 1 1 1 Retinol binding protein receptor Big_1 PF02369.16 PRP77433.1 - 2.1e-08 34.1 14.4 0.00074 19.5 0.0 8.5 9 0 0 9 9 9 1 Bacterial Ig-like domain (group 1) CarboxypepD_reg PF13620.6 PRP77433.1 - 5.9e-06 26.5 13.8 7.7e-05 22.9 0.0 5.5 6 0 0 6 6 6 2 Carboxypeptidase regulatory-like domain MG4 PF17789.1 PRP77433.1 - 0.00014 22.0 5.6 0.062 13.4 0.2 5.7 6 1 0 6 6 6 1 Macroglobulin domain MG4 Invasin_D3 PF09134.10 PRP77433.1 - 0.0055 17.0 7.9 0.056 13.7 0.0 4.8 5 0 0 5 5 5 1 Invasin, domain 3 DUF5496 PF17600.2 PRP77433.1 - 0.049 13.7 0.2 0.15 12.1 0.2 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5496) Transthyretin PF00576.21 PRP77433.1 - 0.059 14.1 0.2 0.35 11.6 0.0 2.4 2 0 0 2 2 2 0 HIUase/Transthyretin family DUF4792 PF16040.5 PRP77433.1 - 0.075 13.0 1.2 0.22 11.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4792) Chromo PF00385.24 PRP77435.1 - 0.0025 17.7 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LRR_9 PF14580.6 PRP77436.1 - 0.01 15.4 0.4 0.01 15.4 0.4 1.9 2 0 0 2 2 2 0 Leucine-rich repeat DUF4404 PF14357.6 PRP77436.1 - 5 7.8 6.4 34 5.2 0.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) IMPDH PF00478.25 PRP77437.1 - 7.9e-38 130.3 1.7 8.9e-38 130.2 1.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 PRP77437.1 - 0.012 15.0 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase DUF4047 PF13256.6 PRP77437.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) SIR2 PF02146.17 PRP77438.1 - 8.1e-35 120.3 0.0 1.1e-34 119.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 PRP77438.1 - 0.00021 21.0 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.16 PRP77438.1 - 0.0089 15.0 0.1 0.44 9.4 0.1 2.0 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit WDCP PF15390.6 PRP77440.1 - 0.00014 20.4 0.1 0.00021 19.9 0.1 1.2 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family DUF1411 PF07199.11 PRP77440.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Pkinase PF00069.25 PRP77441.1 - 6.6e-55 186.3 0.0 7.9e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77441.1 - 8.5e-26 90.8 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP77441.1 - 3.4e-07 29.8 0.1 6.1e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP77441.1 - 0.00081 19.4 0.1 0.013 15.4 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP77441.1 - 0.0027 16.6 0.1 0.092 11.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP77441.1 - 0.004 16.5 0.0 1.1 8.5 0.0 2.2 1 1 0 2 2 2 2 Kinase-like Alpha_kinase PF02816.18 PRP77441.1 - 0.053 13.7 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Alpha-kinase family FTA2 PF13095.6 PRP77441.1 - 0.16 11.6 0.4 0.44 10.1 0.4 1.8 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GATA PF00320.27 PRP77442.1 - 1e-08 34.6 5.6 1e-08 34.6 5.6 2.4 2 0 0 2 2 2 1 GATA zinc finger Rhodanese PF00581.20 PRP77442.1 - 1.1e-08 35.5 0.0 2.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain PHD PF00628.29 PRP77442.1 - 0.0023 17.8 8.2 0.0023 17.8 8.2 2.6 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.22 PRP77442.1 - 0.0076 16.1 8.3 0.0076 16.1 8.3 3.3 1 1 2 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Methyltransf_2 PF00891.18 PRP77443.1 - 3.1e-29 101.8 0.0 4.4e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 PRP77443.1 - 0.00012 22.8 0.0 0.00055 20.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PRP77443.1 - 0.00053 19.6 0.0 0.00076 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP77443.1 - 0.0028 18.3 0.0 0.0055 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation2 PF16864.5 PRP77443.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Ubie_methyltran PF01209.18 PRP77443.1 - 0.059 12.7 0.0 0.26 10.6 0.0 1.9 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 PRP77443.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF1084 PF06454.11 PRP77444.1 - 1.3e-50 172.3 16.7 1.7e-50 171.9 16.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF4271 PF14093.6 PRP77444.1 - 0.0012 18.8 18.5 0.0012 18.8 18.5 2.7 1 1 2 3 3 3 2 Domain of unknown function (DUF4271) DUF1129 PF06570.11 PRP77444.1 - 0.0044 16.5 1.5 0.0044 16.5 1.5 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1129) Hol_Tox PF16935.5 PRP77444.1 - 0.25 11.4 6.9 2.1 8.4 0.1 2.9 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) NAR2 PF16974.5 PRP77444.1 - 1 8.8 4.3 0.7 9.3 1.4 1.9 2 0 0 2 2 2 0 High-affinity nitrate transporter accessory PAP2_C PF14360.6 PRP77444.1 - 8.8 6.9 18.0 0.22 12.1 6.8 3.4 3 1 1 4 4 4 0 PAP2 superfamily C-terminal GST_C_3 PF14497.6 PRP77445.1 - 1.3e-15 57.3 0.2 2.5e-15 56.5 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP77445.1 - 1.7e-10 41.0 0.0 3.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP77445.1 - 3.4e-06 27.2 0.1 5.9e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP77445.1 - 4.9e-06 26.9 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PRP77445.1 - 0.0012 19.5 0.0 0.0048 17.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 PRP77445.1 - 0.0048 17.2 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GluRS_N PF18466.1 PRP77445.1 - 0.047 14.1 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain GPS2_interact PF15784.5 PRP77446.1 - 0.0052 17.2 6.0 0.033 14.6 0.2 2.9 2 0 0 2 2 2 1 G-protein pathway suppressor 2-interacting domain Tyosinase_C PF18132.1 PRP77446.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Tyosinase C-terminal domain RRP36 PF06102.12 PRP77446.1 - 0.21 11.5 7.7 0.049 13.6 3.4 1.9 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 PI3_PI4_kinase PF00454.27 PRP77447.1 - 2.6e-27 96.3 0.0 4e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UCH PF00443.29 PRP77448.1 - 1.4e-56 191.9 2.9 1.7e-56 191.6 2.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP77448.1 - 2.7e-28 99.5 4.3 6.7e-28 98.2 4.3 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PRP77448.1 - 0.24 10.8 7.0 0.39 10.1 4.2 2.6 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1924 PF09086.11 PRP77448.1 - 1 9.8 4.9 4.2 7.8 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1924) LIM PF00412.22 PRP77449.1 - 6.8e-08 32.6 4.1 1.4e-07 31.6 4.1 1.6 1 0 0 1 1 1 1 LIM domain Ank_2 PF12796.7 PRP77450.1 - 2.1e-33 114.7 3.7 1.9e-10 41.2 0.2 4.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 PRP77450.1 - 2.5e-24 84.6 10.7 0.00083 19.7 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 PRP77450.1 - 6.8e-22 75.2 4.7 0.0022 18.3 0.2 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 PRP77450.1 - 2e-20 72.9 4.7 1.4e-07 31.9 0.5 5.5 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP77450.1 - 5.7e-19 67.9 7.2 1.4e-06 28.4 0.1 5.6 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Homeodomain PF00046.29 PRP77450.1 - 9.4e-14 51.0 4.7 2e-13 50.0 4.7 1.6 1 0 0 1 1 1 1 Homeodomain SchA_CurD PF04486.12 PRP77450.1 - 0.0036 17.4 0.0 0.04 14.0 0.0 2.5 3 0 0 3 3 3 1 SchA/CurD like domain Homeobox_KN PF05920.11 PRP77450.1 - 0.0064 16.4 1.5 0.011 15.6 0.4 2.0 2 0 0 2 2 2 1 Homeobox KN domain eIF-1a PF01176.19 PRP77451.1 - 2e-20 72.4 0.8 3.6e-20 71.5 0.1 1.9 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 Glyoxalase_4 PF13669.6 PRP77451.1 - 7.8e-19 68.0 0.0 1.6e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 PRP77451.1 - 8.9e-13 48.6 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PRP77451.1 - 2.5e-06 27.7 0.0 3.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain SelR PF01641.18 PRP77452.1 - 2.5e-52 176.0 0.8 5.4e-52 175.0 0.8 1.6 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 PRP77452.1 - 0.00031 20.9 0.3 0.00068 19.8 0.3 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HLH PF00010.26 PRP77452.1 - 0.026 14.5 0.3 0.12 12.3 0.3 2.2 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain SHOCT PF09851.9 PRP77452.1 - 0.041 13.6 0.0 0.18 11.6 0.0 2.1 1 0 0 1 1 1 0 Short C-terminal domain CwfJ_C_1 PF04677.15 PRP77455.1 - 3.3e-34 117.4 0.0 5.2e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 PRP77455.1 - 4.9e-33 113.9 0.2 4.9e-33 113.9 0.2 3.2 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.25 PRP77456.1 - 8.3e-64 215.5 0.0 9.8e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77456.1 - 9.8e-38 129.9 0.0 1.3e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP77456.1 - 1.7e-08 34.1 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP77456.1 - 1.3e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP77456.1 - 5.2e-05 22.9 0.1 8e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PRP77456.1 - 0.002 18.1 0.0 0.0047 16.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 PRP77456.1 - 0.0088 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 LRR_9 PF14580.6 PRP77458.1 - 4.2e-12 45.9 4.2 9.7e-12 44.7 4.2 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PRP77458.1 - 2.2e-08 34.3 18.0 0.00015 22.0 0.8 4.3 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP77458.1 - 1.8e-06 27.6 16.0 0.00032 20.4 3.5 4.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 PRP77458.1 - 0.21 11.7 9.1 2.7 8.3 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat PRIMA1 PF16101.5 PRP77458.1 - 8.4 6.5 11.5 18 5.4 11.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 D123 PF07065.14 PRP77459.1 - 1.6e-27 96.5 1.3 5.9e-23 81.5 0.0 2.7 3 0 0 3 3 3 2 D123 R2K_3 PF14243.6 PRP77459.1 - 1e-05 25.7 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 PRP77459.1 - 2.8e-05 24.0 0.0 7.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 TFIIA PF03153.13 PRP77459.1 - 7 6.5 25.1 12 5.7 25.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HA PF03457.14 PRP77460.1 - 6e-13 48.9 1.7 0.0001 22.6 0.1 3.9 3 1 0 3 3 3 3 Helicase associated domain CH PF00307.31 PRP77461.1 - 2.2e-41 140.4 1.5 4.5e-14 52.5 0.0 4.0 3 0 0 3 3 3 3 Calponin homology (CH) domain RhoGEF PF00621.20 PRP77461.1 - 3.1e-33 115.6 0.0 3.1e-33 115.6 0.0 2.9 3 1 0 3 3 3 1 RhoGEF domain CDC24 PF06395.11 PRP77461.1 - 1.3e-09 38.2 0.1 0.00047 20.4 0.1 3.0 2 0 0 2 2 2 2 CDC24 Calponin PH PF00169.29 PRP77461.1 - 0.018 15.5 0.0 0.072 13.6 0.0 2.1 1 0 0 1 1 1 0 PH domain UQ_con PF00179.26 PRP77462.1 - 1.2e-35 122.2 0.0 1.4e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PRP77462.1 - 0.001 19.3 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 PRP77462.1 - 0.0024 17.5 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Ank_2 PF12796.7 PRP77463.1 - 2.4e-40 137.0 0.0 4.6e-09 36.7 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77463.1 - 2e-24 85.6 0.5 1.4e-06 28.7 0.0 5.9 3 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP77463.1 - 1.7e-15 56.7 1.9 0.39 11.3 0.0 8.8 4 3 3 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 PRP77463.1 - 3.5e-14 51.5 0.1 0.22 12.2 0.0 8.3 7 2 2 9 9 9 3 Ankyrin repeat Ank_5 PF13857.6 PRP77463.1 - 5.2e-11 42.6 0.0 1.8 9.0 0.0 7.4 2 2 6 8 8 8 4 Ankyrin repeats (many copies) VWA_3_C PF18571.1 PRP77463.1 - 0.0016 18.3 1.0 1e+02 2.9 0.0 5.5 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Endonuc-PvuII PF09225.10 PRP77463.1 - 0.0045 16.8 0.0 2.9 7.6 0.0 3.1 1 1 3 4 4 4 2 Restriction endonuclease PvuII Ank_2 PF12796.7 PRP77465.1 - 5.6e-113 369.7 0.6 9e-14 51.8 0.0 8.8 2 2 11 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77465.1 - 3.1e-61 203.0 7.0 7.8e-07 29.5 0.1 12.9 4 1 11 16 16 16 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP77465.1 - 2.7e-34 116.8 1.1 0.16 12.3 0.0 17.4 5 4 12 18 18 18 7 Ankyrin repeats (many copies) DHHA2 PF02833.14 PRP77465.1 - 5.9e-30 104.3 0.1 1.5e-29 103.0 0.1 1.7 1 0 0 1 1 1 1 DHHA2 domain Ank_3 PF13606.6 PRP77465.1 - 3.6e-29 97.6 0.8 0.11 13.1 0.0 17.5 18 2 1 19 19 19 4 Ankyrin repeat Ank PF00023.30 PRP77465.1 - 1.5e-27 94.8 25.0 0.73 10.4 0.0 19.7 16 3 4 20 20 20 6 Ankyrin repeat DHH PF01368.20 PRP77465.1 - 6.8e-12 45.5 0.0 1.9e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 DHH family Dopey_N PF04118.14 PRP77465.1 - 0.15 11.1 0.1 0.35 9.9 0.0 1.5 2 0 0 2 2 2 0 Dopey, N-terminal PRiA4_ORF3 PF07929.11 PRP77466.1 - 0.99 9.1 6.8 0.52 10.0 0.1 3.0 3 0 0 3 3 3 0 Plasmid pRiA4b ORF-3-like protein GAPT PF11770.8 PRP77466.1 - 4.5 7.1 10.3 6.2 6.7 0.9 2.7 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) Lipase_3 PF01764.25 PRP77468.1 - 1.8e-30 105.7 0.0 3.9e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PRP77468.1 - 0.0021 18.7 0.1 0.0046 17.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 PRP77468.1 - 0.0043 16.6 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 PRP77468.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Rap_GAP PF02145.15 PRP77469.1 - 1.3e-54 184.6 0.0 2.9e-54 183.4 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP XRCC4 PF06632.12 PRP77469.1 - 0.024 13.5 2.4 0.034 13.0 2.4 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DsbG_N PF18257.1 PRP77469.1 - 0.041 14.0 2.6 0.081 13.1 1.1 2.3 2 0 0 2 2 2 0 Disulfide isomerase DsbG N-terminal DUF3226 PF11536.8 PRP77469.1 - 0.076 12.7 1.1 6.8 6.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3226) LRR_8 PF13855.6 PRP77470.1 - 5.7e-46 154.1 73.5 6.5e-08 32.2 9.1 9.8 7 2 2 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 PRP77470.1 - 9.3e-32 108.6 74.3 1.4e-05 25.4 0.0 12.9 7 3 9 16 16 16 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP77470.1 - 2e-16 58.0 77.3 0.34 11.6 1.4 20.5 22 1 1 23 23 23 9 Leucine Rich Repeat LRR_6 PF13516.6 PRP77470.1 - 9.3e-05 22.2 64.8 4.5 7.6 0.1 17.7 19 0 0 19 19 19 5 Leucine Rich repeat Mucin PF01456.17 PRP77474.1 - 0.17 11.9 15.6 0.22 11.5 15.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 PRP77474.1 - 1.1 9.8 7.0 1.4 9.4 7.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CTP_synth_N PF06418.14 PRP77477.1 - 6.8e-125 415.7 0.1 1e-124 415.2 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 PRP77477.1 - 1.9e-52 177.8 0.0 2.8e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PRP77477.1 - 5.5e-07 29.6 0.0 1.6e-06 28.0 0.0 1.8 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.23 PRP77477.1 - 0.054 13.5 0.0 0.11 12.6 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 PRP77477.1 - 0.2 10.8 0.0 0.42 9.7 0.0 1.6 1 0 0 1 1 1 0 Anion-transporting ATPase RhoGEF PF00621.20 PRP77478.1 - 9.5e-42 143.3 0.5 1.6e-41 142.5 0.5 1.4 1 0 0 1 1 1 1 RhoGEF domain MORN PF02493.20 PRP77478.1 - 4.2e-36 120.7 65.1 0.00028 20.6 1.7 13.6 14 1 0 14 14 14 10 MORN repeat Dus PF01207.17 PRP77480.1 - 4.5e-51 173.8 0.0 1.3e-50 172.3 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 PRP77480.1 - 0.0037 16.3 0.0 0.0052 15.8 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain MR_MLE_C PF13378.6 PRP77480.1 - 0.028 14.0 0.0 0.046 13.3 0.0 1.4 1 1 0 1 1 1 0 Enolase C-terminal domain-like WD40 PF00400.32 PRP77481.1 - 5e-14 52.5 7.5 0.0072 17.1 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP77481.1 - 0.00038 20.7 0.1 16 5.9 0.0 4.2 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP77481.1 - 0.0015 17.4 0.0 0.15 10.7 0.0 2.3 1 1 0 2 2 2 2 Nup133 N terminal like Nup160 PF11715.8 PRP77481.1 - 0.044 12.4 0.1 4.7 5.7 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 PRP77481.1 - 0.14 12.7 0.1 2.1 8.9 0.1 2.8 3 0 0 3 3 3 0 PQQ-like domain MRNIP PF15749.5 PRP77482.1 - 1.5e-15 57.9 7.7 4.6e-15 56.3 7.7 1.7 1 1 0 1 1 1 1 MRN-interacting protein LIM PF00412.22 PRP77483.1 - 2.9e-29 101.1 18.7 2.1e-10 40.7 2.6 3.3 3 0 0 3 3 3 3 LIM domain C1_4 PF07975.12 PRP77483.1 - 0.08 13.2 1.5 0.08 13.2 1.5 4.0 3 1 1 4 4 4 0 TFIIH C1-like domain DUF2685 PF10886.8 PRP77483.1 - 3.5 7.9 0.0 3.5 7.9 0.0 4.5 6 1 1 7 7 7 0 Protein of unknown function (DUF2685) Glyco_hydro_125 PF06824.11 PRP77485.1 - 1.3e-142 475.5 0.0 2e-142 475.0 0.0 1.2 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) BST2 PF16716.5 PRP77485.1 - 0.84 10.3 2.9 4.2 8.0 0.1 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 MFS_1 PF07690.16 PRP77486.1 - 1.3e-12 47.3 36.5 6.4e-09 35.2 24.6 3.5 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PRP77486.1 - 2e-06 26.6 9.7 3.2e-06 25.9 9.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 PRP77486.1 - 0.019 13.2 14.9 0.024 12.9 1.5 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GST_C_3 PF14497.6 PRP77487.1 - 5.6e-12 45.7 0.0 8.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP77487.1 - 8.3e-07 29.3 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP77487.1 - 9.8e-06 25.7 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GAD-like PF08887.11 PRP77487.1 - 0.078 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 GAD-like domain Ank_2 PF12796.7 PRP77488.1 - 1.3e-16 61.0 8.3 5e-09 36.6 0.6 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77488.1 - 7.8e-08 32.7 1.0 0.031 14.9 0.0 3.7 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP77488.1 - 7.8e-07 29.3 4.5 0.81 10.2 0.1 4.9 4 1 1 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 PRP77488.1 - 2.7e-05 24.2 0.4 5 8.0 0.0 5.0 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PRP77488.1 - 0.00032 20.9 2.7 1.4 9.3 0.0 4.7 3 2 3 6 6 6 1 Ankyrin repeats (many copies) SPRY PF00622.28 PRP77489.1 - 1e-19 70.8 0.1 1.7e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 SPRY domain CD34_antigen PF06365.12 PRP77489.1 - 0.0083 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 CD34/Podocalyxin family Collectrin PF16959.5 PRP77489.1 - 0.053 13.3 1.1 0.091 12.5 1.1 1.3 1 0 0 1 1 1 0 Renal amino acid transporter EphA2_TM PF14575.6 PRP77489.1 - 0.082 13.8 0.0 0.32 11.9 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 PRP77489.1 - 0.36 10.7 1.3 0.78 9.6 1.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Adaptin_N PF01602.20 PRP77490.1 - 1.3e-145 485.9 4.4 1.7e-145 485.6 4.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 PRP77490.1 - 2.5e-22 79.3 0.6 6.1e-22 78.0 0.6 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 PRP77490.1 - 8.5e-15 55.2 4.4 8.4e-09 35.7 0.0 3.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PRP77490.1 - 1e-07 32.2 0.3 0.013 15.9 0.0 3.8 2 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 PRP77490.1 - 1.4e-06 28.0 0.4 0.33 11.3 0.0 5.0 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.7 PRP77490.1 - 0.017 15.7 0.5 0.49 11.0 0.1 3.1 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 PRP77490.1 - 0.071 13.2 0.0 2.8 8.1 0.0 3.0 2 1 1 3 3 3 0 V-ATPase subunit H Arm PF00514.23 PRP77490.1 - 0.11 12.6 3.3 60 3.9 0.0 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.9 PRP77490.1 - 0.17 10.3 6.5 0.033 12.7 2.0 1.9 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 PRP77490.1 - 0.19 12.3 2.4 18 6.0 0.0 4.2 4 1 0 4 4 3 0 HEAT-like repeat TIP120 PF08623.10 PRP77490.1 - 0.33 10.7 4.4 8.4 6.1 0.1 3.8 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) DNMT1-RFD PF12047.8 PRP77491.1 - 5.4e-06 26.5 0.1 1.1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Claudin_2 PF13903.6 PRP77492.1 - 0.051 13.3 6.8 0.15 11.8 6.8 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3292 PF11696.8 PRP77492.1 - 0.097 11.0 1.0 0.11 10.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Meckelin PF09773.9 PRP77492.1 - 0.24 9.4 1.7 0.3 9.1 1.7 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Pkinase_Tyr PF07714.17 PRP77494.1 - 1.3e-50 172.1 0.0 2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77494.1 - 2.1e-47 161.7 0.0 3.5e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP77494.1 - 1.1e-10 41.4 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 PRP77494.1 - 0.037 13.0 0.0 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain SNO PF01174.19 PRP77495.1 - 3.1e-51 173.9 0.0 4.9e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 PRP77495.1 - 1.7e-08 34.3 0.0 3.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 PRP77495.1 - 0.00096 19.0 0.0 0.0042 16.9 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 PRP77495.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family ChapFlgA PF13144.6 PRP77495.1 - 0.093 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation Ras PF00071.22 PRP77496.1 - 4.9e-25 88.0 0.0 1.1e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Ras family LRR_6 PF13516.6 PRP77496.1 - 2.2e-18 64.7 13.0 0.014 15.4 0.0 6.7 6 0 0 6 6 6 6 Leucine Rich repeat Roc PF08477.13 PRP77496.1 - 4.2e-11 43.1 0.3 1.2e-10 41.7 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FAM76 PF16046.5 PRP77496.1 - 0.00024 20.5 7.8 0.00024 20.5 7.8 3.9 2 1 1 3 3 3 1 FAM76 protein LRR_4 PF12799.7 PRP77496.1 - 0.00089 19.6 8.1 0.046 14.1 2.0 3.4 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP77496.1 - 0.0021 18.4 6.0 21 6.2 0.2 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat Jnk-SapK_ap_N PF09744.9 PRP77496.1 - 0.0071 16.6 16.8 0.0071 16.6 16.8 5.3 3 1 2 5 5 3 1 JNK_SAPK-associated protein-1 MMR_HSR1 PF01926.23 PRP77496.1 - 0.12 12.5 3.5 0.12 12.4 0.0 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase LRR_8 PF13855.6 PRP77496.1 - 0.4 10.5 8.7 6.7 6.6 0.2 4.1 2 2 0 2 2 2 0 Leucine rich repeat AAA_22 PF13401.6 PRP77496.1 - 1.1 9.5 4.4 11 6.2 0.0 4.3 5 0 0 5 5 5 0 AAA domain AAA_16 PF13191.6 PRP77496.1 - 1.3 9.4 0.0 1.3 9.4 0.0 4.1 4 1 0 4 4 3 0 AAA ATPase domain zf-C2H2_11 PF16622.5 PRP77497.1 - 0.0032 17.2 0.8 0.0055 16.4 0.8 1.3 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2 PF00096.26 PRP77497.1 - 0.0086 16.5 0.7 0.015 15.8 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP77497.1 - 0.037 14.9 0.6 0.064 14.1 0.6 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-CSL PF05207.13 PRP77497.1 - 0.098 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 CSL zinc finger Glycos_transf_2 PF00535.26 PRP77498.1 - 3.4e-25 88.8 0.0 5.1e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PRP77498.1 - 1.4e-08 34.9 0.0 3.2e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PRP77498.1 - 1.5e-05 24.6 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NuDC PF16273.5 PRP77501.1 - 0.072 13.6 0.2 0.13 12.8 0.2 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain CTD_bind PF04818.13 PRP77503.1 - 1.3e-08 35.5 0.3 2.8e-08 34.4 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Surp PF01805.20 PRP77503.1 - 4.6e-07 29.7 0.1 8.2e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Surp module zf-CCHC PF00098.23 PRP77503.1 - 0.00017 21.5 1.3 0.00031 20.7 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PRP77503.1 - 0.027 14.3 0.8 0.063 13.1 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 PRP77503.1 - 0.059 13.1 0.7 0.12 12.1 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Isy1 PF06246.12 PRP77504.1 - 1.8e-08 34.3 5.7 1.8e-08 34.3 5.7 2.0 1 1 0 2 2 2 1 Isy1-like splicing family DUF1577 PF07614.11 PRP77504.1 - 0.013 14.6 0.4 0.022 13.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) zf-CCHH PF10283.9 PRP77506.1 - 3.4e-08 33.3 7.9 6.5e-08 32.4 7.9 1.4 1 0 0 1 1 1 1 PBZ domain FHA_2 PF17913.1 PRP77506.1 - 5.4e-06 26.6 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Borrelia_P83 PF05262.11 PRP77506.1 - 0.14 10.6 23.5 0.17 10.4 23.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SET PF00856.28 PRP77507.1 - 1.7e-13 51.3 0.0 3.6e-13 50.2 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 PRP77507.1 - 3.1e-07 30.4 11.5 3.1e-07 30.4 11.5 3.1 2 1 0 2 2 2 1 MYND finger Pkinase PF00069.25 PRP77508.1 - 0.00025 20.5 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Choline_transpo PF04515.12 PRP77509.1 - 7.4e-70 235.7 25.6 7.4e-70 235.7 25.6 2.7 2 1 1 3 3 3 1 Plasma-membrane choline transporter HMG_box PF00505.19 PRP77509.1 - 9.8e-18 64.3 0.1 2.6e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PRP77509.1 - 3.9e-09 37.0 0.0 8.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF1013 PF06242.11 PRP77509.1 - 0.063 13.3 0.1 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) CHDNT PF08073.12 PRP77509.1 - 0.073 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF2921 PF11145.8 PRP77509.1 - 0.99 7.1 3.7 3.1 5.5 3.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2921) VIT1 PF01988.19 PRP77510.1 - 7.5e-44 150.2 8.1 1.7e-42 145.8 8.1 2.0 1 1 0 1 1 1 1 VIT family CinA PF02464.17 PRP77511.1 - 7.1e-20 71.1 0.2 1.2e-19 70.4 0.2 1.3 1 0 0 1 1 1 1 Competence-damaged protein RR_TM4-6 PF06459.12 PRP77511.1 - 1.6 8.5 11.1 0.83 9.4 2.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 PRP77511.1 - 4.9 6.9 7.5 3.3 7.4 0.4 2.1 2 0 0 2 2 2 0 Connexin AAA_12 PF13087.6 PRP77512.1 - 5.1e-40 137.2 0.0 1.1e-39 136.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PRP77512.1 - 4.7e-23 82.3 13.2 2.9e-12 47.0 0.0 4.1 3 1 0 4 4 4 2 AAA domain zf-GRF PF06839.12 PRP77512.1 - 1.3e-13 50.8 2.5 2.7e-13 49.8 2.5 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF2439 PF10382.9 PRP77512.1 - 6.6e-10 39.2 0.3 2.1e-09 37.6 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.18 PRP77512.1 - 1.9e-08 34.3 0.0 0.0024 17.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 PRP77512.1 - 0.0036 17.1 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PRP77512.1 - 0.094 13.0 0.0 0.46 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain ECH_2 PF16113.5 PRP77513.1 - 1.1e-38 133.6 0.0 3.1e-38 132.1 0.0 1.8 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PRP77513.1 - 9.1e-13 48.1 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase WD40_like PF17005.5 PRP77513.1 - 2.3e-07 30.5 0.8 0.00032 20.1 0.1 2.4 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 PRP77513.1 - 0.00064 20.0 0.5 2.3 8.6 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP77513.1 - 0.016 16.1 9.8 3 8.9 0.2 4.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Herpeto_peptide PF14409.6 PRP77513.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon PMBR PF09373.10 PRP77513.1 - 0.12 12.6 0.0 0.41 10.9 0.0 2.0 1 0 0 1 1 1 0 Pseudomurein-binding repeat AAA_12 PF13087.6 PRP77516.1 - 5.1e-40 137.2 0.0 1.1e-39 136.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PRP77516.1 - 4.7e-23 82.3 13.2 2.9e-12 47.0 0.0 4.1 3 1 0 4 4 4 2 AAA domain zf-GRF PF06839.12 PRP77516.1 - 1.3e-13 50.8 2.5 2.7e-13 49.8 2.5 1.5 1 0 0 1 1 1 1 GRF zinc finger DUF2439 PF10382.9 PRP77516.1 - 6.6e-10 39.2 0.3 2.1e-09 37.6 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.18 PRP77516.1 - 1.9e-08 34.3 0.0 0.0024 17.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 PRP77516.1 - 0.0036 17.1 0.0 0.0073 16.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PRP77516.1 - 0.094 13.0 0.0 0.46 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain CinA PF02464.17 PRP77517.1 - 7.1e-20 71.1 0.2 1.2e-19 70.4 0.2 1.3 1 0 0 1 1 1 1 Competence-damaged protein RR_TM4-6 PF06459.12 PRP77517.1 - 1.6 8.5 11.1 0.83 9.4 2.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 PRP77517.1 - 4.9 6.9 7.5 3.3 7.4 0.4 2.1 2 0 0 2 2 2 0 Connexin VIT1 PF01988.19 PRP77518.1 - 7.5e-44 150.2 8.1 1.7e-42 145.8 8.1 2.0 1 1 0 1 1 1 1 VIT family Choline_transpo PF04515.12 PRP77519.1 - 7.4e-70 235.7 25.6 7.4e-70 235.7 25.6 2.7 2 1 1 3 3 3 1 Plasma-membrane choline transporter HMG_box PF00505.19 PRP77519.1 - 9.8e-18 64.3 0.1 2.6e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PRP77519.1 - 3.9e-09 37.0 0.0 8.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain DUF1013 PF06242.11 PRP77519.1 - 0.063 13.3 0.1 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) CHDNT PF08073.12 PRP77519.1 - 0.073 13.0 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 CHDNT (NUC034) domain DUF2921 PF11145.8 PRP77519.1 - 0.99 7.1 3.7 3.1 5.5 3.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2921) F-box-like PF12937.7 PRP77521.1 - 4.9e-10 39.1 0.6 1.1e-09 38.1 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP77521.1 - 8.4e-08 31.9 1.4 1.9e-07 30.7 1.4 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 PRP77521.1 - 0.031 14.8 0.3 0.052 14.1 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Ank_4 PF13637.6 PRP77522.1 - 0.044 14.4 0.0 0.62 10.7 0.0 2.1 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP77524.1 - 5e-31 107.1 0.2 8.5e-08 32.7 0.0 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77524.1 - 1.6e-27 95.5 8.5 7.3e-09 36.0 0.0 8.2 6 2 3 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP77524.1 - 2.2e-16 59.7 5.5 0.015 15.6 0.0 9.2 4 2 7 11 11 11 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP77524.1 - 3.6e-16 58.8 9.9 0.27 11.8 0.0 10.2 12 0 0 12 12 12 5 Ankyrin repeat Ank_3 PF13606.6 PRP77524.1 - 5.4e-12 44.8 4.7 8.7 7.3 0.0 9.1 8 1 1 9 9 9 3 Ankyrin repeat GST_N_2 PF13409.6 PRP77525.1 - 6.9e-09 35.9 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP77525.1 - 8.4e-08 32.5 0.1 2e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PRP77525.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP77525.1 - 0.032 14.4 0.0 0.079 13.2 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 PRP77526.1 - 1.6e-28 100.0 0.0 3.2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP77526.1 - 5.1e-18 65.3 15.3 6.9e-18 64.9 15.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP77526.1 - 1.3e-11 44.9 0.0 8.1e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PRP77526.1 - 0.0011 18.4 0.2 0.23 10.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 PRP77526.1 - 0.0014 18.4 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_15 PF13175.6 PRP77526.1 - 0.023 14.4 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 PRP77526.1 - 0.035 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 PRP77526.1 - 0.079 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 PRP77526.1 - 0.11 13.0 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP77526.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_2 PF12796.7 PRP77527.1 - 2.7e-49 165.7 0.0 3.4e-10 40.4 0.1 6.0 2 1 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77527.1 - 5.7e-39 132.0 4.5 2.6e-06 27.9 0.0 9.6 3 3 8 11 11 11 10 Ankyrin repeats (many copies) Ank PF00023.30 PRP77527.1 - 1.1e-26 92.0 19.3 0.058 13.9 0.1 14.0 14 1 1 15 15 15 8 Ankyrin repeat Ank_5 PF13857.6 PRP77527.1 - 2e-22 78.9 5.2 0.35 11.3 0.0 11.2 6 3 5 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77527.1 - 8.9e-22 74.8 2.6 2.9 8.7 0.0 13.5 15 0 0 15 15 15 3 Ankyrin repeat YlzJ PF14035.6 PRP77527.1 - 8.5e-07 29.1 1.7 1.1 9.5 0.0 7.1 8 0 0 8 8 8 1 YlzJ-like protein Hairy_orange PF07527.13 PRP77527.1 - 0.67 10.2 3.6 1.9e+02 2.4 0.0 5.8 8 0 0 8 8 8 0 Hairy Orange ABC_tran PF00005.27 PRP77528.1 - 1.7e-28 99.9 0.0 3.2e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP77528.1 - 1.2e-16 60.8 14.6 1.8e-16 60.2 14.6 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP77528.1 - 4.1e-12 46.5 0.0 2.3e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 PRP77528.1 - 0.002 17.9 0.0 0.56 9.9 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein SMC_N PF02463.19 PRP77528.1 - 0.0022 17.5 0.1 0.33 10.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PRP77528.1 - 0.025 14.3 0.1 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 PRP77528.1 - 0.06 12.7 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 PRP77528.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain URO-D PF01208.17 PRP77529.1 - 3.8e-133 443.9 0.0 4.4e-133 443.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ank_2 PF12796.7 PRP77531.1 - 1.8e-12 47.7 0.0 6.1e-06 26.7 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77531.1 - 2.3e-10 40.8 0.0 0.00037 21.0 0.0 4.5 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP77531.1 - 9e-06 25.9 0.4 7.2 7.2 0.0 5.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 PRP77531.1 - 1.3e-05 25.2 0.0 3.1 8.7 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 PRP77531.1 - 6.1e-05 23.2 0.2 2.5 8.6 0.0 4.5 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP77532.1 - 8.3e-12 45.4 0.5 0.00032 21.2 0.0 4.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP77532.1 - 1.3e-09 38.5 0.0 0.00015 22.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP77532.1 - 1.8e-05 24.9 0.2 0.027 14.8 0.0 3.8 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP77532.1 - 0.00028 21.2 2.1 5.3 7.7 0.0 4.9 5 1 0 5 5 5 1 Ankyrin repeat DUF1731 PF08338.11 PRP77532.1 - 0.0081 16.0 0.1 0.24 11.2 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1731) Ank_3 PF13606.6 PRP77532.1 - 0.024 15.2 0.0 8.3 7.3 0.0 4.1 5 0 0 5 5 5 0 Ankyrin repeat RhoGEF PF00621.20 PRP77533.1 - 5.3e-40 137.6 7.8 1.2e-39 136.4 7.8 1.7 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PRP77533.1 - 1e-06 29.2 0.0 5.4e-06 26.9 0.0 2.2 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 PRP77533.1 - 0.0045 16.9 0.0 0.046 13.7 0.0 2.7 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.7 PRP77535.1 - 8.4e-52 173.7 0.0 4.3e-09 36.8 0.0 6.8 1 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77535.1 - 9e-39 131.4 7.3 5.2e-06 26.9 0.1 9.9 7 2 2 10 10 10 7 Ankyrin repeats (many copies) XPG_N PF00752.17 PRP77535.1 - 2e-30 105.2 0.0 4.2e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 PRP77535.1 - 7.4e-29 100.0 0.0 1.6e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Ank_5 PF13857.6 PRP77535.1 - 3.5e-27 94.1 10.2 0.0049 17.2 0.0 14.5 4 3 12 16 16 16 7 Ankyrin repeats (many copies) Ank PF00023.30 PRP77535.1 - 2.1e-18 65.8 17.3 0.57 10.7 0.1 13.9 13 2 0 13 13 13 3 Ankyrin repeat Ank_3 PF13606.6 PRP77535.1 - 3e-18 64.0 4.2 7.7 7.4 0.0 14.4 16 0 0 16 16 16 2 Ankyrin repeat 5_3_exonuc PF01367.20 PRP77535.1 - 6.2e-05 23.5 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF3734 PF12536.8 PRP77535.1 - 0.11 12.9 0.3 80 3.6 0.0 4.4 3 2 0 4 4 4 0 Patatin phospholipase HHH_5 PF14520.6 PRP77535.1 - 0.11 13.1 0.0 0.31 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1612 PF07756.12 PRP77535.1 - 2 8.6 9.9 56 4.0 0.0 5.7 7 0 0 7 7 7 0 Protein of unknown function (DUF1612) DUF4142 PF13628.6 PRP77535.1 - 2.3 8.5 8.3 0.86 9.8 3.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4142) G-alpha PF00503.20 PRP77536.1 - 9.5e-86 288.1 0.2 2.1e-85 287.0 0.2 1.6 1 0 0 1 1 1 1 G-protein alpha subunit Arm PF00514.23 PRP77536.1 - 5.4e-33 112.0 14.4 3.1e-09 36.5 0.0 8.0 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 PRP77536.1 - 1.4e-15 57.7 0.0 0.0028 17.7 0.0 4.4 1 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PRP77536.1 - 2.6e-15 56.5 11.5 0.0012 19.2 0.1 5.1 3 1 0 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 PRP77536.1 - 3e-15 56.3 10.1 0.0042 17.6 0.1 6.6 5 1 1 6 6 6 5 HEAT-like repeat HEAT PF02985.22 PRP77536.1 - 9.7e-15 53.4 11.0 0.0042 17.2 0.0 8.5 9 0 0 9 9 9 4 HEAT repeat DNA_alkylation PF08713.11 PRP77536.1 - 5.5e-08 32.8 0.0 0.13 12.0 0.0 3.8 1 1 0 3 3 3 3 DNA alkylation repair enzyme Arf PF00025.21 PRP77536.1 - 7.3e-08 32.1 0.1 1.7e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Proteasom_PSMB PF10508.9 PRP77536.1 - 6.4e-05 21.7 0.2 0.0013 17.3 0.1 2.3 1 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 PRP77536.1 - 9.4e-05 21.2 2.9 0.035 12.7 0.4 3.0 1 1 1 2 2 2 2 Adaptin N terminal region API5 PF05918.11 PRP77536.1 - 0.017 14.0 0.4 3.9 6.2 0.0 3.0 1 1 2 3 3 3 0 Apoptosis inhibitory protein 5 (API5) CHASE6_C PF17150.4 PRP77536.1 - 0.026 15.2 0.0 8.5 7.1 0.0 4.0 4 0 0 4 4 4 0 C-terminal domain of two-partite extracellular sensor domain Gtr1_RagA PF04670.12 PRP77536.1 - 0.034 13.5 0.6 5.7 6.2 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF3361 PF11841.8 PRP77536.1 - 0.046 13.7 0.1 8.7 6.3 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 PRP77536.1 - 0.29 11.9 8.9 7 7.6 0.1 4.9 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat RhoGEF PF00621.20 PRP77538.1 - 5.6e-45 153.8 4.3 1.3e-44 152.6 4.3 1.7 1 0 0 1 1 1 1 RhoGEF domain WW PF00397.26 PRP77538.1 - 1e-07 31.9 8.1 0.00013 21.9 4.4 2.6 2 0 0 2 2 2 2 WW domain BSP_II PF05432.11 PRP77538.1 - 1.2 8.8 37.3 0.034 13.9 28.5 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Zip PF02535.22 PRP77538.1 - 2.6 7.2 12.1 4.7 6.3 12.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 PRP77538.1 - 5.8 5.6 23.9 17 4.0 23.9 1.8 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 PRP77538.1 - 6.7 6.5 32.5 29 4.4 32.5 2.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.9 PRP77539.1 - 1.1e-46 158.8 30.1 1.1e-46 158.8 30.1 2.1 2 0 0 2 2 2 1 DDRGK domain Pkinase_Tyr PF07714.17 PRP77540.1 - 2.3e-27 95.9 2.0 1.3e-26 93.5 2.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77540.1 - 2.6e-12 46.7 2.9 1.9e-10 40.5 2.9 2.7 1 1 0 1 1 1 1 Protein kinase domain DUF3977 PF13122.6 PRP77540.1 - 0.015 15.5 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3977) DP-EP PF08985.11 PRP77541.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 DP-EP family Tim17 PF02466.19 PRP77542.1 - 6.4e-17 61.9 2.4 1.1e-16 61.2 2.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 PRP77542.1 - 1.9 8.7 7.6 1.8 8.7 3.6 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5518) C2 PF00168.30 PRP77543.1 - 2.6e-39 133.6 0.1 1.3e-19 70.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 PRP77543.1 - 2.6e-24 86.1 0.0 1.3e-17 64.2 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 PRP77543.1 - 6.2e-15 55.6 1.2 1.2e-14 54.7 1.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP77543.1 - 0.0072 16.7 1.3 0.029 14.8 1.3 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 PRP77544.1 - 2.2e-05 24.7 0.1 0.00025 21.3 0.0 2.4 2 0 0 2 2 2 1 C2 domain SMP_LBD PF17047.5 PRP77544.1 - 0.015 14.7 0.1 0.2 11.1 0.0 2.4 2 1 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain MRC1 PF09444.10 PRP77544.1 - 0.08 13.4 2.1 0.4 11.2 0.3 2.4 2 0 0 2 2 2 0 MRC1-like domain PAS_9 PF13426.7 PRP77546.1 - 1e-12 48.2 0.1 2.1e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 PAS domain GAF PF01590.26 PRP77546.1 - 4.2e-09 37.1 0.0 1.1e-08 35.8 0.0 1.6 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 PRP77546.1 - 0.00026 21.3 0.0 0.00043 20.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain PAS_3 PF08447.12 PRP77546.1 - 0.00083 19.6 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 PRP77546.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 PRP77546.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.7 PRP77546.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 PAS domain zf-RING_2 PF13639.6 PRP77547.1 - 8.4e-09 35.6 7.7 8.4e-09 35.6 7.7 2.1 2 0 0 2 2 1 1 Ring finger domain WWE PF02825.20 PRP77547.1 - 1.3e-08 35.3 0.6 3.9e-08 33.8 0.6 1.9 1 0 0 1 1 1 1 WWE domain zf-rbx1 PF12678.7 PRP77547.1 - 2.9e-07 30.7 6.1 9.8e-07 29.0 6.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PRP77547.1 - 3e-07 30.1 7.1 3e-07 30.1 7.1 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP77547.1 - 9.6e-06 25.2 2.8 9.6e-06 25.2 2.8 2.0 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_1 PF14446.6 PRP77547.1 - 0.00069 19.5 7.0 0.0093 15.9 7.5 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 PRP77547.1 - 0.0092 16.0 2.1 0.0092 16.0 2.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Cas_Csn2 PF09711.10 PRP77547.1 - 0.015 15.0 0.5 0.034 13.8 0.5 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) zf-RanBP PF00641.18 PRP77547.1 - 0.02 14.2 1.7 0.02 14.2 1.7 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-C3HC4 PF00097.25 PRP77547.1 - 0.48 10.3 9.9 0.18 11.7 6.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PRP77547.1 - 0.88 9.2 12.5 0.029 14.0 5.7 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PRP77547.1 - 0.95 9.5 7.1 2.8 8.0 7.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.7 PRP77547.1 - 0.99 9.6 10.5 0.16 12.1 6.0 2.2 2 0 0 2 2 2 0 RING-variant domain OrfB_Zn_ribbon PF07282.11 PRP77547.1 - 1.2 9.1 3.8 2.4 8.2 0.3 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C3HC4_3 PF13920.6 PRP77547.1 - 1.4 8.9 12.8 0.036 13.9 5.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 PRP77547.1 - 4.3 7.1 13.8 0.4 10.4 5.3 2.7 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_5 PF14634.6 PRP77547.1 - 6.6 6.8 13.6 0.44 10.5 6.7 2.5 2 0 0 2 2 2 0 zinc-RING finger domain RasGAP PF00616.19 PRP77550.1 - 2e-28 99.5 1.7 2e-16 60.4 0.5 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 PRP77550.1 - 1.4e-20 73.9 1.8 3.9e-20 72.4 0.4 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 PRP77550.1 - 0.0008 19.2 0.1 0.0082 15.9 0.1 2.5 1 1 1 2 2 2 1 CRAL/TRIO domain MFS_1 PF07690.16 PRP77552.1 - 3.6e-25 88.7 56.2 1.9e-19 69.8 32.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 PRP77552.1 - 5.1e-17 62.0 20.2 5.5e-17 61.9 9.4 2.6 2 1 0 2 2 2 2 Ion channel regulatory protein UNC-93 Kinesin PF00225.23 PRP77553.1 - 2.7e-104 348.7 0.1 8e-104 347.1 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP77553.1 - 5.9e-24 84.7 0.8 8.9e-23 80.9 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding FapA PF03961.13 PRP77553.1 - 4.9 5.7 17.8 1.3 7.5 5.8 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF724 PF05266.14 PRP77553.1 - 5.6 6.7 22.1 0.27 11.1 7.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Med9 PF07544.13 PRP77553.1 - 9.5 6.4 19.7 3.6 7.8 6.0 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HMGL-like PF00682.19 PRP77555.1 - 6.4e-46 157.0 0.4 5.5e-34 117.9 0.2 2.0 1 1 1 2 2 2 2 HMGL-like FAM178 PF14816.6 PRP77555.1 - 0.0026 16.8 0.2 0.0086 15.1 0.2 1.7 1 1 1 2 2 2 1 Family of unknown function, FAM178 PSDC PF12588.8 PRP77555.1 - 0.055 13.4 0.1 0.098 12.6 0.1 1.3 1 0 0 1 1 1 0 Phophatidylserine decarboxylase DUF2070 PF09843.9 PRP77556.1 - 8.4 4.5 10.1 10 4.3 10.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CCSMST1 PF15013.6 PRP77557.1 - 0.015 15.4 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 CCSMST1 family LRR_8 PF13855.6 PRP77558.1 - 3.3e-13 49.2 24.4 5.1e-11 42.2 3.4 4.0 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 PRP77558.1 - 2.6e-11 43.5 22.1 0.0002 21.6 3.3 4.9 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP77558.1 - 8.7e-07 28.6 2.2 0.00056 19.5 1.1 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 PRP77558.1 - 6.3e-05 22.7 12.9 0.41 10.8 0.2 5.3 4 1 1 5 5 5 3 Leucine Rich repeat DUF3557 PF12078.8 PRP77558.1 - 0.00037 20.5 1.0 0.0007 19.6 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3557) Ras PF00071.22 PRP77559.1 - 4.4e-54 182.5 0.3 5e-54 182.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP77559.1 - 1.4e-20 73.7 0.0 1.8e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP77559.1 - 3.4e-07 29.9 0.1 3.6e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP77559.1 - 5.5e-05 23.1 0.1 0.098 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP77559.1 - 0.00022 20.8 0.7 0.00046 19.8 0.3 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP77559.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FERM_M PF00373.18 PRP77561.1 - 1.3e-37 128.8 0.1 1.8e-20 73.5 0.0 2.4 2 0 0 2 2 2 2 FERM central domain FERM_N PF09379.10 PRP77561.1 - 1.2e-26 92.4 0.1 4e-11 42.7 0.0 3.6 3 0 0 3 3 3 2 FERM N-terminal domain FERM_f0 PF16511.5 PRP77561.1 - 8.1e-25 86.9 0.0 3.6e-13 49.6 0.0 3.7 3 0 0 3 3 3 3 N-terminal or F0 domain of Talin-head FERM RA PF00788.23 PRP77561.1 - 2e-05 25.2 0.0 0.18 12.5 0.0 3.3 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain ACBP PF00887.19 PRP77561.1 - 0.00017 21.7 0.0 0.21 11.8 0.0 2.9 3 0 0 3 3 3 2 Acyl CoA binding protein FERM_F1 PF18379.1 PRP77561.1 - 0.00039 20.4 0.1 0.02 14.9 0.0 2.6 2 0 0 2 2 2 1 FERM F1 ubiquitin-like domain PI3K_rbd PF00794.18 PRP77561.1 - 0.017 15.3 0.9 13 6.0 0.0 3.2 3 0 0 3 3 3 0 PI3-kinase family, ras-binding domain PID PF00640.23 PRP77561.1 - 0.02 14.9 0.0 7 6.7 0.0 2.6 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) TUG-UBL1 PF11470.8 PRP77561.1 - 0.035 14.3 0.0 0.81 10.0 0.0 2.7 2 0 0 2 2 2 0 TUG ubiquitin-like domain DWNN PF08783.11 PRP77561.1 - 0.038 14.3 0.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 DWNN domain UN_NPL4 PF11543.8 PRP77561.1 - 0.11 13.0 0.1 3.8 8.1 0.0 2.7 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Gelsolin PF00626.22 PRP77562.1 - 1.3e-41 140.3 1.1 1.4e-12 47.3 0.0 5.7 5 1 0 5 5 5 5 Gelsolin repeat VHP PF02209.19 PRP77562.1 - 5.6e-14 51.9 0.2 1.3e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 Villin headpiece domain UDPGT PF00201.18 PRP77563.1 - 5.5e-09 35.4 0.1 2.3e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 PRP77563.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain VCBS PF13517.6 PRP77564.1 - 7.1e-18 65.0 21.0 1.2e-06 29.0 0.1 6.9 4 3 3 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PRP77564.1 - 5.4e-10 39.2 15.5 0.0029 17.7 0.0 5.7 5 0 0 5 5 5 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 PRP77564.1 - 0.05 13.0 4.1 7.7 5.8 0.1 4.9 5 1 1 6 6 6 0 Insecticide toxin TcdB middle/N-terminal region RhoGEF PF00621.20 PRP77565.1 - 9.7e-41 140.0 0.4 9.7e-41 140.0 0.4 1.8 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 PRP77565.1 - 5e-05 23.8 0.1 0.00014 22.4 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 PRP77565.1 - 0.014 15.3 0.2 0.03 14.2 0.2 1.6 1 0 0 1 1 1 0 PH domain IQ PF00612.27 PRP77565.1 - 0.1 12.4 0.1 0.36 10.8 0.1 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif PH_13 PF16652.5 PRP77565.1 - 0.33 10.7 3.2 1.1 9.0 0.9 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain RNA12 PF10443.9 PRP77566.1 - 2.6e-36 125.3 0.2 1.8e-26 92.9 0.2 2.2 2 0 0 2 2 2 2 RNA12 protein RRM_1 PF00076.22 PRP77566.1 - 3.2e-06 26.9 0.1 0.09 12.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.6 PRP77566.1 - 1.1e-05 25.7 0.0 3.7e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP77566.1 - 2.1e-05 25.0 0.0 6.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 PRP77566.1 - 0.00034 21.2 0.1 0.0013 19.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 PRP77566.1 - 0.0013 19.2 5.5 1.6 9.2 2.9 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PRP77566.1 - 0.0026 17.5 0.0 0.0074 16.0 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain N6_N4_Mtase PF01555.18 PRP77566.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 DNA methylase NACHT PF05729.12 PRP77566.1 - 0.011 15.7 0.3 0.16 11.9 0.3 2.5 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 PRP77566.1 - 0.014 15.3 0.4 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 PRP77566.1 - 0.032 13.5 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FapA PF03961.13 PRP77566.1 - 0.055 12.1 2.9 0.11 11.1 2.9 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A RsgA_GTPase PF03193.16 PRP77566.1 - 0.063 13.2 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 PRP77566.1 - 0.07 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 PRP77566.1 - 0.08 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 PRP77566.1 - 0.12 11.9 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PRP77566.1 - 0.13 12.4 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain DivIC PF04977.15 PRP77566.1 - 5.5 6.8 6.7 1.5 8.7 1.5 2.6 3 0 0 3 3 3 0 Septum formation initiator Pyr_redox_2 PF07992.14 PRP77567.1 - 1.6e-08 34.2 0.8 0.00016 21.0 0.1 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PRP77567.1 - 3.3e-06 26.6 0.0 0.0033 16.7 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 PRP77567.1 - 5.3e-05 23.7 0.2 0.00015 22.3 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP77567.1 - 0.00018 21.2 0.2 0.00031 20.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP77567.1 - 0.00038 20.6 0.2 0.0012 19.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PRP77567.1 - 0.00047 19.4 0.1 0.00079 18.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PRP77567.1 - 0.0012 18.1 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP77567.1 - 0.0086 14.8 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PRP77567.1 - 0.023 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 PRP77567.1 - 0.061 13.8 0.1 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 PRP77567.1 - 0.076 12.1 1.9 0.15 11.1 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A AhpC-TSA PF00578.21 PRP77567.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 AhpC/TSA family Syndecan PF01034.20 PRP77568.1 - 9.7e-06 25.4 1.8 2.1e-05 24.4 1.8 1.5 1 0 0 1 1 1 1 Syndecan domain Podoplanin PF05808.11 PRP77568.1 - 0.00076 19.6 0.2 0.0015 18.6 0.2 1.4 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 PRP77568.1 - 0.016 14.1 0.3 0.029 13.2 0.3 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Syndecan PF01034.20 PRP77569.1 - 0.0026 17.7 0.8 0.0052 16.7 0.8 1.5 1 0 0 1 1 1 1 Syndecan domain Podoplanin PF05808.11 PRP77569.1 - 0.0026 17.9 0.1 0.0056 16.8 0.1 1.5 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 PRP77569.1 - 0.016 15.8 0.0 0.04 14.5 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage LRR_9 PF14580.6 PRP77570.1 - 1.1e-20 73.8 6.9 1.1e-20 73.8 6.9 3.7 4 0 0 4 4 4 1 Leucine-rich repeat LRR_4 PF12799.7 PRP77570.1 - 5.1e-12 45.8 35.6 7.1e-06 26.3 7.3 6.0 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP77570.1 - 8e-11 41.5 28.1 4.8e-07 29.4 11.8 4.3 3 2 1 4 4 4 3 Leucine rich repeat DUF641 PF04859.12 PRP77570.1 - 0.0023 18.3 6.0 0.0023 18.3 6.0 12.0 6 4 7 13 13 13 1 Plant protein of unknown function (DUF641) LRR_6 PF13516.6 PRP77570.1 - 0.085 13.0 19.8 6.4 7.1 0.9 5.9 5 0 0 5 5 5 0 Leucine Rich repeat DUF2052 PF09747.9 PRP77572.1 - 0.004 17.3 3.7 0.004 17.3 3.7 2.2 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) OspD PF03207.13 PRP77572.1 - 0.045 13.1 0.5 0.092 12.1 0.5 1.4 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) NARP1 PF12569.8 PRP77572.1 - 2.2 7.1 7.7 0.2 10.5 2.6 1.7 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RXT2_N PF08595.11 PRP77572.1 - 7.4 6.6 10.9 1.6 8.8 2.6 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Presenilin PF01080.17 PRP77572.1 - 9.7 4.8 6.6 5.2 5.7 4.3 1.6 2 0 0 2 2 2 0 Presenilin ApoO PF09769.9 PRP77573.1 - 0.0041 17.1 0.9 0.073 13.0 0.0 2.5 3 0 0 3 3 3 1 Apolipoprotein O Snapin_Pallidin PF14712.6 PRP77573.1 - 0.006 17.0 10.2 1.6 9.2 0.7 3.2 2 1 1 3 3 3 1 Snapin/Pallidin Cnn_1N PF07989.11 PRP77573.1 - 0.013 15.7 7.8 0.13 12.5 2.7 2.9 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 SKA2 PF16740.5 PRP77573.1 - 0.027 14.3 6.0 0.16 11.8 2.5 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 T2SSF PF00482.23 PRP77573.1 - 0.032 14.2 1.7 5.5 7.0 0.0 3.1 2 1 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF573 PF04504.14 PRP77573.1 - 0.074 13.7 0.6 1.6 9.5 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF573 APG6_N PF17675.1 PRP77573.1 - 0.12 13.0 10.9 0.17 12.4 7.6 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 PRP77573.1 - 0.15 12.3 14.4 1.6 9.0 6.8 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding PDDEXK_4 PF14281.6 PRP77573.1 - 0.16 12.1 1.8 0.22 11.6 1.8 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF4200 PF13863.6 PRP77573.1 - 0.24 11.8 12.9 4.2 7.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) bZIP_2 PF07716.15 PRP77573.1 - 0.29 11.3 14.8 1 9.5 0.7 3.5 2 1 1 3 3 3 0 Basic region leucine zipper YabA PF06156.13 PRP77573.1 - 0.35 11.5 8.6 1.4 9.6 3.5 2.8 2 1 1 3 3 3 0 Initiation control protein YabA BRE1 PF08647.11 PRP77573.1 - 0.36 10.9 11.0 0.54 10.4 5.1 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase FUSC PF04632.12 PRP77573.1 - 0.51 8.8 1.1 0.54 8.7 1.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADIP PF11559.8 PRP77573.1 - 0.59 10.2 15.0 0.24 11.5 10.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 PRP77573.1 - 0.87 8.9 4.8 3.4 6.9 4.4 1.9 2 0 0 2 2 2 0 FAM76 protein Spc7 PF08317.11 PRP77573.1 - 0.93 8.3 11.8 1 8.2 8.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 PRP77573.1 - 1.8 9.3 11.8 20 5.9 0.1 4.1 2 1 1 3 3 3 0 SlyX ABC_tran_CTD PF16326.5 PRP77573.1 - 3 8.2 10.6 29 5.0 6.1 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF3450 PF11932.8 PRP77573.1 - 3.3 7.0 11.4 1.8 7.8 5.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) COG2 PF06148.11 PRP77573.1 - 7.3 6.7 10.6 23 5.0 0.2 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FlxA PF14282.6 PRP77573.1 - 8.4 6.5 11.1 5.1 7.2 0.3 2.9 2 1 1 3 3 3 0 FlxA-like protein Uso1_p115_C PF04871.13 PRP77573.1 - 8.6 6.7 11.9 85 3.5 0.0 3.0 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region V_ATPase_I PF01496.19 PRP77573.1 - 9.3 4.0 6.9 5.7 4.7 4.8 1.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family PspB PF06667.12 PRP77573.1 - 9.3 6.4 7.9 17 5.5 0.0 3.3 2 1 1 3 3 3 0 Phage shock protein B PP2C PF00481.21 PRP77574.1 - 2e-41 142.4 0.0 2.7e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PRP77574.1 - 2.5e-09 37.1 0.0 5.8e-09 35.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP77574.1 - 0.011 15.7 0.3 5.5 6.8 0.2 3.4 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Coiled-coil_56 PF09813.9 PRP77574.1 - 0.042 13.9 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 Mago-bind PF09282.10 PRP77575.1 - 3.5e-14 52.4 0.6 5.4e-14 51.8 0.6 1.3 1 0 0 1 1 1 1 Mago binding Oxysterol_BP PF01237.18 PRP77577.1 - 1e-59 202.3 14.6 7.6e-58 196.1 10.6 2.7 2 1 0 2 2 2 1 Oxysterol-binding protein TPR_MLP1_2 PF07926.12 PRP77578.1 - 1.5e-15 57.4 19.4 1.5e-15 57.4 19.4 16.4 6 3 10 18 18 18 5 TPR/MLP1/MLP2-like protein SAP PF02037.27 PRP77578.1 - 3.2e-05 23.6 0.1 3.2e-05 23.6 0.1 3.2 3 0 0 3 3 3 1 SAP domain HeH PF12949.7 PRP77578.1 - 0.00012 21.8 0.2 0.00051 19.7 0.2 2.1 1 0 0 1 1 1 1 HeH/LEM domain HemY_N PF07219.13 PRP77578.1 - 9.6 6.5 9.4 2.4 8.4 2.4 3.4 2 0 0 2 2 2 0 HemY protein N-terminus Pkinase PF00069.25 PRP77579.1 - 1.1e-67 228.2 0.0 1.3e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77579.1 - 6.9e-32 110.7 0.0 1.1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP77579.1 - 0.00064 19.1 0.1 0.0014 18.1 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP77579.1 - 0.0038 16.2 0.0 0.0068 15.4 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP77579.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP77579.1 - 0.027 13.8 0.1 1 8.6 0.0 3.1 2 1 0 2 2 2 0 Kinase-like LOR PF04525.12 PRP77581.1 - 1.6e-13 50.7 0.1 2.9e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 LURP-one-related C2 PF00168.30 PRP77581.1 - 0.0067 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Muted PF14942.6 PRP77582.1 - 2.8e-13 50.4 2.8 4.8e-13 49.7 2.8 1.4 1 1 0 1 1 1 1 Organelle biogenesis, Muted-like protein SNF2_N PF00176.23 PRP77583.1 - 2.9e-60 203.9 0.6 5.8e-60 202.9 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 PRP77583.1 - 4.8e-37 125.9 0.3 1.2e-21 76.6 0.0 2.8 2 0 0 2 2 2 2 Bromodomain Helicase_C PF00271.31 PRP77583.1 - 1e-17 64.5 0.2 5.1e-17 62.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP77583.1 - 2e-10 40.9 0.0 9.2e-10 38.8 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 PRP77583.1 - 1e-08 34.9 6.9 2e-08 34.0 6.9 1.5 1 0 0 1 1 1 1 PHD-finger DEAD PF00270.29 PRP77583.1 - 6.8e-07 29.2 0.0 2.2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 PRP77583.1 - 0.0028 17.3 0.0 0.009 15.6 0.0 1.8 1 0 0 1 1 1 1 DEAD_2 PHD_2 PF13831.6 PRP77583.1 - 0.01 15.3 2.4 0.019 14.5 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 PRP77583.1 - 0.35 11.1 3.9 0.62 10.4 2.6 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain LRR_9 PF14580.6 PRP77584.1 - 8.8e-15 54.6 7.2 6.1e-10 38.9 0.8 3.3 1 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 PRP77584.1 - 1e-11 44.8 24.4 0.0014 19.0 0.8 5.5 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP77584.1 - 3.5e-11 42.7 15.8 5.3e-05 22.9 1.3 4.9 4 2 3 7 7 7 6 Leucine rich repeat GAF_2 PF13185.6 PRP77584.1 - 3.9e-07 30.5 0.0 1.5e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 PRP77584.1 - 1.7e-05 25.5 0.0 5.3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 PRP77584.1 - 0.0042 17.4 0.0 0.0091 16.3 0.0 1.5 1 0 0 1 1 1 1 GAF domain LRR_6 PF13516.6 PRP77584.1 - 0.72 10.1 11.7 5.2 7.4 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich repeat DUF4472 PF14739.6 PRP77584.1 - 5.7 7.7 6.9 0.24 12.1 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) FAD_binding_3 PF01494.19 PRP77585.1 - 3.2e-68 230.6 0.0 4.6e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain AAA_28 PF13521.6 PRP77585.1 - 5.6e-14 52.7 0.0 1.4e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DAO PF01266.24 PRP77585.1 - 5.8e-13 49.2 0.0 8.9e-06 25.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP77585.1 - 2e-08 33.8 0.0 0.0025 17.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP77585.1 - 8e-06 25.2 0.1 0.00059 19.0 0.2 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 PRP77585.1 - 9.8e-06 26.0 0.0 0.01 16.4 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP77585.1 - 1.1e-05 25.5 0.1 3.6e-05 23.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PRP77585.1 - 0.0001 21.8 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 PRP77585.1 - 0.0039 16.5 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 PRP77585.1 - 0.016 14.0 0.3 1 8.0 0.2 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 PRP77585.1 - 0.017 14.5 0.4 0.055 12.8 0.4 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 PRP77585.1 - 0.018 14.2 0.2 0.028 13.5 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PRP77585.1 - 0.026 13.8 0.0 2.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PRP77585.1 - 0.03 13.5 0.1 1 8.4 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AAA_18 PF13238.6 PRP77585.1 - 0.11 13.0 0.0 0.43 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 PRP77586.1 - 1.2e-50 171.3 0.0 1.7e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 PRP77586.1 - 7.3e-20 71.4 0.3 7.2e-11 42.5 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Roc PF08477.13 PRP77586.1 - 1.2e-19 70.7 0.0 2.3e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_4 PF13637.6 PRP77586.1 - 6.5e-16 58.5 0.0 2.1e-06 28.2 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP77586.1 - 7.9e-13 48.2 2.3 0.00018 21.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP77586.1 - 1.9e-11 44.0 0.2 1.6e-05 25.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77586.1 - 1.9e-10 40.0 0.2 0.017 15.6 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Arf PF00025.21 PRP77586.1 - 1.7e-06 27.6 0.0 3.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_16 PF13191.6 PRP77586.1 - 0.18 12.1 0.0 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Pectate_lyase_3 PF12708.7 PRP77587.1 - 6.2e-74 248.5 1.1 8.1e-58 195.8 1.2 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 PRP77587.1 - 2.4e-05 23.9 0.0 0.041 13.6 0.0 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ald_Xan_dh_C2 PF02738.18 PRP77588.1 - 1.7e-171 571.4 0.2 7.9e-171 569.2 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin-binding domain of aldehyde dehydrogenase Med31 PF05669.12 PRP77588.1 - 6.1e-35 119.1 14.8 1.1e-34 118.3 14.8 1.4 1 0 0 1 1 1 1 SOH1 Ald_Xan_dh_C PF01315.22 PRP77588.1 - 1.6e-31 108.9 0.2 3.8e-31 107.7 0.2 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 PRP77588.1 - 7.9e-28 97.3 0.0 1.5e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 PRP77588.1 - 1.4e-25 89.1 0.2 3.7e-25 87.8 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 PRP77588.1 - 7.8e-23 80.6 0.0 8.6e-22 77.3 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PRP77588.1 - 6.8e-06 26.0 0.0 1.9e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain CH PF00307.31 PRP77589.1 - 1.5e-18 67.0 0.1 2.4e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain TRAF_BIRC3_bd PF16673.5 PRP77589.1 - 0.077 12.8 1.6 0.18 11.6 1.6 1.5 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain TolA_bind_tri PF16331.5 PRP77589.1 - 0.084 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Ax_dynein_light PF10211.9 PRP77589.1 - 0.088 12.7 0.6 0.16 11.9 0.6 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain FlaC_arch PF05377.11 PRP77589.1 - 0.089 13.2 1.6 0.17 12.3 0.3 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 PRP77589.1 - 0.16 12.3 1.9 9.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 PRP77589.1 - 0.32 11.4 3.5 1.9 8.9 0.2 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper LRR_4 PF12799.7 PRP77590.1 - 3.3e-11 43.2 19.5 0.031 14.7 0.1 7.3 5 1 3 9 9 9 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP77590.1 - 2.1e-08 33.6 17.3 0.64 10.2 0.0 9.0 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 PRP77590.1 - 0.018 15.5 18.3 7.1 7.6 0.1 8.6 8 1 0 8 8 8 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 PRP77590.1 - 5.2 7.4 12.7 63 3.9 0.1 5.2 4 2 1 5 5 5 0 Ste50p, sterile alpha motif DUF1687 PF07955.11 PRP77591.1 - 0.07 13.6 0.1 0.07 13.6 0.1 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1687) ACT_4 PF13291.6 PRP77591.1 - 0.15 12.6 0.5 0.42 11.2 0.5 1.7 1 0 0 1 1 1 0 ACT domain Baculo_PEP_C PF04513.12 PRP77591.1 - 0.96 9.5 7.0 1.1 9.3 5.5 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF747 PF05346.11 PRP77592.1 - 8e-98 327.8 27.6 1.2e-97 327.2 27.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Glyco_hydro_88 PF07470.13 PRP77592.1 - 3.9e-16 59.1 0.5 7.6e-16 58.1 0.5 1.5 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 PRP77592.1 - 0.0075 15.8 0.8 0.28 10.6 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 ERG2_Sigma1R PF04622.12 PRP77593.1 - 4.8e-47 160.0 0.0 5.7e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NTP_transferase PF00483.23 PRP77593.1 - 0.075 12.6 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase Rhomboid PF01694.22 PRP77594.1 - 5.4e-35 120.6 13.4 5.4e-35 120.6 13.4 2.7 4 0 0 4 4 4 1 Rhomboid family DUF1751 PF08551.10 PRP77594.1 - 0.013 16.0 0.2 0.013 16.0 0.2 3.8 5 1 1 6 6 6 0 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.15 PRP77594.1 - 0.51 10.2 15.1 0.11 12.4 2.6 2.7 3 0 0 3 3 3 0 Der1-like family NARP1 PF12569.8 PRP77596.1 - 2.3e-166 554.7 21.2 2.3e-166 554.7 21.2 2.9 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 PRP77596.1 - 3.7e-18 65.9 1.0 0.0062 17.2 0.0 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP77596.1 - 5.4e-17 60.5 18.2 0.00019 21.3 0.7 10.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_14 PF13428.6 PRP77596.1 - 2e-15 56.2 10.0 0.12 13.2 0.1 9.1 8 2 3 11 11 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 PRP77596.1 - 7.5e-15 55.2 14.1 0.0054 17.2 0.0 7.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP77596.1 - 1.7e-13 49.7 5.1 0.0012 18.6 0.3 8.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP77596.1 - 8.3e-12 44.3 4.9 0.37 11.1 0.2 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP77596.1 - 2.6e-11 43.6 11.3 0.00012 22.2 1.3 5.2 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PRP77596.1 - 6.7e-09 35.5 0.1 0.033 14.5 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP77596.1 - 8e-09 35.0 0.5 0.06 13.0 0.1 6.8 7 0 0 7 7 7 1 TPR repeat Fis1_TPR_C PF14853.6 PRP77596.1 - 8.1e-08 32.2 7.6 7 6.8 0.0 6.7 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 PRP77596.1 - 6.4e-07 29.0 2.4 0.011 15.7 0.1 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP77596.1 - 2.5e-06 27.7 13.9 0.056 13.7 0.0 6.9 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP77596.1 - 6.9e-06 26.4 1.2 19 6.2 0.0 7.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 PRP77596.1 - 0.00076 19.6 0.1 0.94 9.7 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 PRP77596.1 - 0.0042 17.6 0.4 0.42 11.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Peptidase_C11 PF03415.14 PRP77596.1 - 0.046 13.1 0.3 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Clostripain family GST_N PF02798.20 PRP77597.1 - 2.3e-12 47.1 0.0 4.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP77597.1 - 2.5e-12 46.8 0.0 4.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP77597.1 - 1.6e-11 44.4 0.0 2.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP77597.1 - 2e-09 37.6 0.0 3.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP77597.1 - 1.2e-08 34.9 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP77597.1 - 4.9e-08 33.1 0.0 8.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain His_Phos_2 PF00328.22 PRP77598.1 - 2.5e-18 66.6 0.0 5.9e-13 48.9 0.1 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) VWA_3 PF13768.6 PRP77599.1 - 2.5e-17 63.2 0.0 4.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 PRP77599.1 - 2.2e-10 40.7 0.0 1.4e-09 38.1 0.0 2.2 1 1 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 PRP77599.1 - 3.4e-10 40.4 0.0 5.2e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 von Willebrand factor type A domain VIT_2 PF13757.6 PRP77599.1 - 1.7e-05 24.6 0.1 5e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain PHD PF00628.29 PRP77600.1 - 1.5e-10 40.7 2.4 2.6e-10 40.0 2.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 PRP77600.1 - 0.0096 16.2 3.4 0.016 15.5 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 PRP77600.1 - 0.02 15.1 1.4 0.23 11.7 1.8 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-rbx1 PF12678.7 PRP77600.1 - 0.044 14.1 0.8 0.094 13.0 0.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 PRP77600.1 - 0.086 13.1 0.6 0.27 11.5 0.6 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 PRP77600.1 - 1.9 8.6 4.2 1.1 9.5 1.5 2.0 2 0 0 2 2 2 0 KIAA1045 RING finger PP2C_C PF07830.13 PRP77600.1 - 2.9 8.4 5.5 9.7 6.7 5.1 2.1 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain ADK_lid PF05191.14 PRP77600.1 - 7.7 6.6 5.9 2.3 8.3 0.8 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid Nha1_C PF08619.10 PRP77601.1 - 8.7 5.4 29.4 2.8 7.1 15.8 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Ribosomal_L35Ae PF01247.18 PRP77602.1 - 1.4e-38 131.0 0.1 1.6e-38 130.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 PRP77602.1 - 0.0018 18.4 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain PBP3 PF18056.1 PRP77602.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Penicillin Binding Protein 3 Domain Multi_Drug_Res PF00893.19 PRP77603.1 - 0.035 14.8 0.5 0.063 13.9 0.5 1.3 1 0 0 1 1 1 0 Small Multidrug Resistance protein Arf PF00025.21 PRP77604.1 - 1.4e-60 203.7 0.0 1.9e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 PRP77604.1 - 1.5e-11 44.1 0.2 8.5e-08 31.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PRP77604.1 - 3.3e-08 33.8 0.0 6.9e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP77604.1 - 1.9e-07 30.7 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PRP77604.1 - 9.9e-07 28.5 0.0 1.3e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PRP77604.1 - 2e-06 27.9 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP77604.1 - 1.9e-05 24.1 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 PRP77604.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GMC_oxred_N PF00732.19 PRP77605.1 - 5.8e-28 98.1 1.5 1.3e-14 54.3 0.1 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP77605.1 - 1.4e-15 58.1 0.1 3.7e-15 56.7 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 PRP77605.1 - 0.0013 17.9 0.1 0.0022 17.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 PRP77605.1 - 0.003 17.2 0.1 0.027 14.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP77605.1 - 0.0039 16.5 0.0 0.0088 15.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP77605.1 - 0.056 12.7 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP77605.1 - 0.17 12.2 1.1 0.28 11.4 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pkinase_Tyr PF07714.17 PRP77606.1 - 2.4e-58 197.5 0.0 2.4e-57 194.2 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77606.1 - 8.3e-37 127.0 0.0 8.4e-36 123.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Beta_helix PF13229.6 PRP77606.1 - 1.6e-11 44.3 103.2 1.7e-07 31.3 23.9 7.2 2 2 4 7 7 7 6 Right handed beta helix region Chlam_PMP PF02415.17 PRP77606.1 - 0.0057 17.1 8.8 0.013 15.9 4.8 15.1 16 0 0 16 16 16 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kdo PF06293.14 PRP77606.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP77606.1 - 0.072 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF5123 PF17161.4 PRP77606.1 - 0.12 13.4 29.7 1.6 9.8 0.4 6.4 5 1 1 7 7 7 0 Domain of unknown function (DUF5123) CRAL_TRIO PF00650.20 PRP77608.1 - 4.1e-25 88.4 0.0 6.7e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP77608.1 - 0.00056 20.0 0.1 0.002 18.3 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRF PF00473.17 PRP77609.1 - 0.1 12.7 0.2 0.26 11.4 0.2 1.7 1 0 0 1 1 1 0 Corticotropin-releasing factor family Urm1 PF09138.11 PRP77610.1 - 2.8e-38 130.2 0.1 3.1e-38 130.0 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 PRP77610.1 - 0.00012 22.7 0.0 0.00015 22.3 0.0 1.1 1 0 0 1 1 1 1 ThiS family ubiquitin PF00240.23 PRP77612.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PHD PF00628.29 PRP77613.1 - 4e-10 39.4 4.7 7.6e-10 38.5 4.7 1.5 1 0 0 1 1 1 1 PHD-finger HARE-HTH PF05066.13 PRP77613.1 - 0.00051 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain zf-HC5HC2H PF13771.6 PRP77613.1 - 0.0011 19.1 1.1 0.0038 17.4 1.1 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PRP77613.1 - 0.027 14.6 0.5 0.065 13.4 0.5 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 PRP77613.1 - 0.33 10.9 2.0 0.74 9.8 2.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 PRP77613.1 - 0.94 9.7 7.6 0.33 11.2 2.1 2.5 2 1 1 3 3 3 0 FANCL C-terminal domain ABC_membrane PF00664.23 PRP77615.1 - 4.5e-64 216.7 19.5 3.5e-37 128.5 1.2 3.3 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 PRP77615.1 - 9e-53 178.5 0.1 4.6e-31 108.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PRP77615.1 - 9.6e-15 54.6 1.1 9.4e-05 21.9 0.0 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PRP77615.1 - 5.5e-07 29.7 0.9 0.064 13.3 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase MTABC_N PF16185.5 PRP77615.1 - 3.2e-06 26.8 6.4 9e-06 25.4 6.4 1.7 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_16 PF13191.6 PRP77615.1 - 1.5e-05 25.5 0.1 0.024 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 PRP77615.1 - 2.6e-05 24.2 2.2 0.31 10.8 0.1 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PRP77615.1 - 3.3e-05 23.5 0.6 0.34 10.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP77615.1 - 4.5e-05 24.0 0.0 0.022 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PRP77615.1 - 0.00031 20.5 0.1 0.006 16.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 PRP77615.1 - 0.00055 19.7 0.1 0.31 10.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PRP77615.1 - 0.00073 19.5 1.9 0.35 10.8 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 PRP77615.1 - 0.0013 18.9 2.3 0.18 11.8 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 PRP77615.1 - 0.0022 17.6 0.5 0.05 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP77615.1 - 0.0036 17.6 0.8 2.2 8.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PRP77615.1 - 0.011 15.3 0.4 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 PRP77615.1 - 0.033 13.5 0.7 3.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 PRP77615.1 - 0.039 13.2 0.7 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 PRP77615.1 - 0.074 12.1 0.0 12 4.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 PRP77615.1 - 0.074 13.5 0.4 4.5 7.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 PRP77615.1 - 0.12 12.1 0.5 16 5.2 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Roc PF08477.13 PRP77615.1 - 0.17 12.1 1.1 13 6.0 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 PRP77615.1 - 0.19 10.5 0.3 1.8 7.3 0.1 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.17 PRP77615.1 - 0.35 10.9 2.4 0.95 9.5 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 PRP77615.1 - 0.54 9.9 1.7 32 4.2 0.2 2.8 2 1 0 2 2 2 0 AAA domain PDT PF00800.18 PRP77616.1 - 2.4e-54 183.9 0.0 3.6e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 PRP77616.1 - 2.5e-10 39.9 0.0 3.4e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 PRP77616.1 - 0.0038 17.8 0.0 0.48 11.0 0.0 2.6 2 0 0 2 2 2 1 ACT domain Peptidase_S10 PF00450.22 PRP77617.1 - 1.1e-115 387.4 1.6 1.6e-115 386.9 1.6 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase LAG1-DNAbind PF09271.11 PRP77618.1 - 0.076 13.6 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 LAG1, DNA binding K_oxygenase PF13434.6 PRP77619.1 - 6.9e-24 84.6 0.0 1.7e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 PRP77619.1 - 1.5e-10 40.9 0.0 0.00018 20.9 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PRP77619.1 - 1.2e-06 28.0 0.0 0.00053 19.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP77619.1 - 1.7e-06 28.1 0.0 0.0018 18.3 0.0 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 PRP77619.1 - 0.0024 18.1 0.1 4.1 7.7 0.1 3.0 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PRP77619.1 - 0.061 13.9 0.1 0.65 10.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Helicase_C PF00271.31 PRP77620.1 - 1.9e-17 63.6 2.8 4.3e-15 56.0 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain HA2 PF04408.23 PRP77620.1 - 8.4e-14 51.8 0.0 8.4e-14 51.8 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 PRP77620.1 - 9.6e-10 38.5 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 PRP77620.1 - 1.9e-07 31.3 0.0 4.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 PRP77620.1 - 2.4e-07 31.1 0.1 1.4e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP77620.1 - 0.05 13.3 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 PRP77620.1 - 0.062 13.2 0.0 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 PRP77620.1 - 0.11 12.9 0.2 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Response_reg PF00072.24 PRP77622.1 - 2e-22 79.5 0.0 9.1e-22 77.3 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 PRP77622.1 - 4.2e-22 78.8 0.3 1.3e-21 77.2 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP77622.1 - 3e-15 56.0 0.4 8.2e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Glyco_hydro_16 PF00722.21 PRP77622.1 - 1.3e-05 24.7 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAS_9 PF13426.7 PRP77622.1 - 0.00061 20.0 0.1 2.7 8.3 0.0 4.1 3 0 0 3 3 3 1 PAS domain PAS_8 PF13188.7 PRP77622.1 - 0.0017 18.3 0.1 0.014 15.4 0.1 2.5 2 0 0 2 2 2 1 PAS domain Carb_bind PF10645.9 PRP77622.1 - 0.021 15.1 6.0 0.054 13.7 6.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding HIP1_clath_bdg PF16515.5 PRP77622.1 - 1.2 9.8 6.5 0.25 12.0 2.5 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ubiquitin PF00240.23 PRP77623.1 - 8.4e-06 25.4 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Baseplate_J PF04865.14 PRP77623.1 - 0.037 13.2 0.1 0.044 12.9 0.1 1.0 1 0 0 1 1 1 0 Baseplate J-like protein CH PF00307.31 PRP77624.1 - 5.1e-32 110.3 0.0 1.6e-16 60.4 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain HOOK PF05622.12 PRP77624.1 - 0.0028 15.9 11.5 0.0028 15.9 11.5 3.8 3 1 1 4 4 4 1 HOOK protein YabA PF06156.13 PRP77624.1 - 0.0041 17.7 2.2 0.0041 17.7 2.2 5.3 3 1 2 5 5 5 1 Initiation control protein YabA KLRAQ PF10205.9 PRP77624.1 - 0.013 15.7 4.7 0.013 15.7 4.7 5.0 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein CH_2 PF06294.11 PRP77624.1 - 0.023 14.8 0.0 2.2 8.4 0.0 3.1 2 0 0 2 2 2 0 CH-like domain in sperm protein PAC1 PF16094.5 PRP77625.1 - 1.1e-08 34.6 0.4 1.6e-07 30.8 0.3 2.5 1 1 1 2 2 2 1 Proteasome assembly chaperone 4 RNA_pol_Rpb6 PF01192.22 PRP77626.1 - 1.5e-16 60.0 0.3 2.8e-16 59.2 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 ComK PF06338.11 PRP77626.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 ComK protein UPF0029 PF01205.19 PRP77627.1 - 5.4e-33 113.5 1.0 2.2e-32 111.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 PRP77627.1 - 1.4e-06 28.6 2.0 0.00041 20.6 2.0 2.9 1 1 0 1 1 1 1 RWD domain Aminotran_1_2 PF00155.21 PRP77629.1 - 6.4e-36 124.3 0.0 9.6e-36 123.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II PIF1 PF05970.14 PRP77630.1 - 4.8e-50 170.8 0.1 1e-48 166.4 0.1 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 PRP77630.1 - 5.2e-22 78.5 0.0 8.5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP77630.1 - 3.3e-09 37.2 0.0 8.9e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 PRP77630.1 - 3.9e-09 35.0 0.1 2.6e-05 22.4 0.0 2.7 3 0 0 3 3 3 2 Helicase AAA_22 PF13401.6 PRP77630.1 - 4.5e-07 30.2 0.1 2e-06 28.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PRP77630.1 - 4.8e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PRP77630.1 - 1.7e-05 24.6 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNF220 PF15926.5 PRP77630.1 - 0.00013 21.7 4.5 0.042 13.5 0.1 2.8 2 1 0 3 3 3 2 E3 ubiquitin-protein ligase RNF220 RsgA_GTPase PF03193.16 PRP77630.1 - 0.00031 20.7 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Viral_helicase1 PF01443.18 PRP77630.1 - 0.00042 20.1 0.0 0.12 12.1 0.0 3.6 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 PRP77630.1 - 0.00043 20.7 0.0 0.00093 19.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP77630.1 - 0.0012 19.3 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain F-box PF00646.33 PRP77630.1 - 0.0016 18.3 2.3 0.0036 17.1 2.3 1.7 1 0 0 1 1 1 1 F-box domain NTPase_1 PF03266.15 PRP77630.1 - 0.0026 17.7 0.2 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 NTPase DEAD PF00270.29 PRP77630.1 - 0.0056 16.5 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase F-box_4 PF15966.5 PRP77630.1 - 0.0067 16.3 0.5 0.35 10.8 0.0 3.1 3 0 0 3 3 3 1 F-box AAA_7 PF12775.7 PRP77630.1 - 0.0083 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 PRP77630.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein UvrD_C_2 PF13538.6 PRP77630.1 - 0.0093 15.8 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain MeaB PF03308.16 PRP77630.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 PRP77630.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 PRP77630.1 - 0.027 13.7 0.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zn-C2H2_12 PF18112.1 PRP77630.1 - 0.056 13.9 2.4 0.74 10.3 0.0 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 PRP77630.1 - 0.07 14.0 1.3 2.6 9.1 0.6 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Bac_DnaA PF00308.18 PRP77630.1 - 0.071 12.9 0.0 0.31 10.9 0.0 1.9 1 1 0 1 1 1 0 Bacterial dnaA protein Mg_chelatase PF01078.21 PRP77630.1 - 0.075 12.4 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI zf-Di19 PF05605.12 PRP77630.1 - 0.081 13.2 6.6 1.7 9.0 0.2 2.9 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding IstB_IS21 PF01695.17 PRP77630.1 - 0.12 12.1 0.1 0.6 9.8 0.1 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein TK PF00265.18 PRP77630.1 - 0.12 12.2 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 1 0 Thymidine kinase AAA_14 PF13173.6 PRP77630.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 PRP77630.1 - 0.13 12.1 0.7 1.2 9.0 0.7 2.2 1 1 0 1 1 1 0 Helicase F-box-like PF12937.7 PRP77630.1 - 0.16 11.9 2.1 0.17 11.8 0.3 2.0 2 0 0 2 2 2 0 F-box-like T2SSE PF00437.20 PRP77630.1 - 0.17 11.0 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 PRP77630.1 - 0.18 11.6 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.6 PRP77630.1 - 1.2 8.9 4.6 6.2 6.5 0.0 2.8 3 1 0 3 3 2 0 AAA domain zf-C2H2_9 PF16293.5 PRP77630.1 - 1.3 8.9 5.2 3.8 7.4 0.0 3.3 4 0 0 4 4 3 0 C2H2 type zinc-finger (1 copy) PTEN_C2 PF10409.9 PRP77636.1 - 7e-12 45.3 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 PRP77636.1 - 0.00088 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PH PF00169.29 PRP77636.1 - 0.0013 19.2 0.0 0.0047 17.4 0.0 2.0 1 0 0 1 1 1 1 PH domain CDKN3 PF05706.12 PRP77636.1 - 0.019 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 PRP77636.1 - 0.031 13.8 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PRP77636.1 - 0.041 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PRP77636.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DNA_pol_phi PF04931.13 PRP77636.1 - 6.8 4.7 5.6 11 4.0 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi UQ_con PF00179.26 PRP77637.1 - 6.2e-47 158.8 0.0 7.2e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PRP77637.1 - 9.2e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Choline_kinase PF01633.20 PRP77638.1 - 3e-34 118.5 0.0 6.1e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PRP77638.1 - 4.8e-10 39.8 0.0 7.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_MLP1_2 PF07926.12 PRP77639.1 - 0.00014 21.9 39.5 0.00053 20.0 8.2 8.3 3 2 4 7 7 7 3 TPR/MLP1/MLP2-like protein SRR PF07709.11 PRP77639.1 - 0.026 14.8 0.3 0.13 12.7 0.0 2.5 2 0 0 2 2 2 0 Seven Residue Repeat DUF5082 PF16888.5 PRP77639.1 - 0.11 12.8 85.6 0.48 10.7 19.7 6.6 3 1 3 6 6 6 0 Domain of unknown function (DUF5082) Filament PF00038.21 PRP77639.1 - 0.31 10.6 122.8 0.05 13.2 50.6 4.1 1 1 2 3 3 3 0 Intermediate filament protein Ank_2 PF12796.7 PRP77640.1 - 2e-28 98.8 0.0 9.6e-07 29.3 0.0 5.0 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77640.1 - 2.5e-22 78.9 0.5 1e-07 32.4 0.1 7.5 4 2 5 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77640.1 - 8.1e-15 53.5 0.8 0.13 12.9 0.0 8.2 7 1 1 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 PRP77640.1 - 8.1e-11 41.9 2.1 0.033 14.5 0.0 6.9 4 4 4 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP77640.1 - 1.9e-07 31.2 4.5 0.14 12.6 0.2 6.1 8 0 0 8 8 8 2 Ankyrin repeat DUF3447 PF11929.8 PRP77640.1 - 2.1e-06 27.6 0.0 0.43 10.6 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF3447) F-box-like PF12937.7 PRP77640.1 - 6.6e-05 22.7 0.1 0.00016 21.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP77640.1 - 0.001 18.9 1.2 0.018 14.9 1.2 2.6 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP77641.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like Histidinol_dh PF00815.20 PRP77642.1 - 6.1e-133 443.8 0.0 9.6e-133 443.1 0.0 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase Aminotran_1_2 PF00155.21 PRP77642.1 - 1.5e-47 162.5 0.0 2.5e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II His_biosynth PF00977.21 PRP77642.1 - 1e-40 139.7 1.5 2.1e-40 138.6 1.5 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein PRA-CH PF01502.18 PRP77642.1 - 2.1e-23 81.9 0.6 4.6e-23 80.8 0.6 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase HAD_2 PF13419.6 PRP77642.1 - 5.3e-18 65.7 0.0 1.1e-17 64.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PRA-PH PF01503.17 PRP77642.1 - 1.6e-10 41.2 0.4 3.6e-10 40.1 0.4 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Hydrolase PF00702.26 PRP77642.1 - 1.2e-09 38.7 0.0 3.1e-08 34.2 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP77642.1 - 0.00014 21.8 0.2 0.00085 19.3 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like PRT_C PF08372.10 PRP77642.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Aminotran_5 PF00266.19 PRP77642.1 - 0.058 12.3 0.0 9.7 5.0 0.0 3.0 3 0 0 3 3 3 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PRP77642.1 - 0.18 10.3 0.0 0.31 9.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme LRR_8 PF13855.6 PRP77643.1 - 3.7e-48 161.1 90.0 1.7e-09 37.3 6.5 13.2 7 3 5 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 PRP77643.1 - 2.3e-37 126.4 104.8 0.00024 21.4 5.3 17.4 9 4 5 18 18 18 16 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP77643.1 - 7.7e-32 110.6 0.2 2.5e-31 108.9 0.2 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77643.1 - 3e-21 76.0 0.0 5.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP77643.1 - 2e-10 41.0 5.1 7.1e-10 39.3 5.1 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP77643.1 - 9.3e-06 25.5 75.7 3.3 8.6 0.7 20.5 22 1 0 22 22 21 4 Leucine Rich Repeat Collectrin PF16959.5 PRP77643.1 - 0.048 13.4 0.5 0.096 12.5 0.5 1.5 1 0 0 1 1 1 0 Renal amino acid transporter TMEM154 PF15102.6 PRP77643.1 - 0.14 12.1 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 PRP77643.1 - 0.2 12.6 0.1 0.88 10.5 0.1 2.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PRP77643.1 - 0.23 11.8 0.7 4.5 7.6 0.1 2.5 2 0 0 2 2 2 0 Orf78 (ac78) FeoB_associated PF12669.7 PRP77643.1 - 0.95 9.9 2.9 3.2 8.2 2.9 1.9 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein LRR_6 PF13516.6 PRP77643.1 - 1.5 9.1 68.5 0.83 9.9 0.0 17.6 20 0 0 20 20 19 0 Leucine Rich repeat RGS PF00615.19 PRP77644.1 - 3.7e-25 88.5 0.0 6.5e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain RFXA_RFXANK_bdg PF15289.6 PRP77644.1 - 0.69 10.3 7.5 0.64 10.4 2.0 2.3 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain zf-DNL PF05180.12 PRP77645.1 - 3.1e-28 97.5 0.0 4.9e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 PRP77645.1 - 0.031 14.2 1.7 2.8 8.0 0.0 2.6 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 PRP77645.1 - 0.034 14.2 0.1 0.05 13.6 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 PRP77645.1 - 0.34 10.3 2.3 2.5 7.5 1.1 2.3 1 1 1 2 2 2 0 Transcription factor zinc-finger CpXC PF14353.6 PRP77645.1 - 0.81 9.7 3.3 7.1 6.7 0.3 2.4 1 1 1 2 2 2 0 CpXC protein Pro_CA PF00484.19 PRP77646.1 - 1.8e-45 155.0 0.5 3.3e-45 154.2 0.5 1.4 1 0 0 1 1 1 1 Carbonic anhydrase Peptidase_M11 PF05548.11 PRP77646.1 - 1.3e-10 40.9 0.2 5.7e-10 38.8 0.2 2.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 NPCBM_assoc PF10633.9 PRP77646.1 - 5.4e-05 23.4 8.1 0.011 15.9 0.0 4.8 6 0 0 6 6 6 2 NPCBM-associated, NEW3 domain of alpha-galactosidase Peptidase_M66 PF10462.9 PRP77646.1 - 0.00091 18.3 0.1 0.0022 17.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase M66 Motile_Sperm PF00635.26 PRP77646.1 - 0.011 15.6 0.1 10 6.0 0.0 3.5 3 0 0 3 3 3 0 MSP (Major sperm protein) domain MSP1a PF11670.8 PRP77646.1 - 0.023 14.0 1.3 0.12 11.7 0.6 2.3 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) Reprolysin_5 PF13688.6 PRP77646.1 - 0.065 13.4 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12 Astacin PF01400.24 PRP77646.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) fn3_5 PF06280.12 PRP77646.1 - 0.54 11.0 6.2 6.6 7.5 0.2 4.9 4 1 1 6 6 6 0 Fn3-like domain Choline_kinase PF01633.20 PRP77647.1 - 2.5e-53 180.8 0.2 4.5e-38 131.0 0.2 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 PRP77647.1 - 2.4e-07 30.9 0.0 3.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family bZIP_1 PF00170.21 PRP77649.1 - 4.8e-13 49.0 8.0 4.8e-13 49.0 8.0 2.8 2 1 1 3 3 3 2 bZIP transcription factor bZIP_Maf PF03131.17 PRP77649.1 - 2.9e-07 30.9 7.3 2.9e-07 30.9 7.3 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 PRP77649.1 - 3.3e-06 27.1 5.3 3.3e-06 27.1 5.3 3.0 2 1 1 3 3 3 2 Basic region leucine zipper V_ATPase_I PF01496.19 PRP77649.1 - 0.014 13.4 2.6 0.019 12.9 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 PRP77649.1 - 0.13 12.5 7.5 0.25 11.6 7.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 PRP77649.1 - 1.1 10.0 4.2 0.56 10.9 1.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 PRP77649.1 - 1.5 9.4 6.5 2.4 8.7 6.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region WDCP PF15390.6 PRP77649.1 - 3 6.1 7.0 0.2 10.0 2.2 1.4 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family DUF3261 PF11659.8 PRP77650.1 - 0.19 11.6 0.5 1.1 9.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3261) UPF0203 PF05254.12 PRP77651.1 - 6.5e-17 61.5 1.4 7.7e-17 61.3 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 PRP77651.1 - 0.00084 19.6 1.3 0.0015 18.8 1.3 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 PRP77651.1 - 0.0028 17.6 0.6 0.053 13.5 0.0 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 PRP77651.1 - 0.0031 17.5 2.1 0.87 9.7 0.2 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 PRP77651.1 - 0.034 14.3 2.4 0.051 13.7 0.1 2.1 2 0 0 2 2 2 0 CHCH domain Pkinase_Tyr PF07714.17 PRP77652.1 - 2.2e-44 151.7 0.6 3.7e-44 151.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase RasGEF PF00617.19 PRP77652.1 - 1.8e-43 148.8 0.1 5.8e-43 147.2 0.1 1.9 1 0 0 1 1 1 1 RasGEF domain Pkinase PF00069.25 PRP77652.1 - 7.4e-34 117.3 0.0 1.6e-33 116.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RhoGAP PF00620.27 PRP77652.1 - 1.6e-26 92.9 0.2 4.2e-26 91.6 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain RGS PF00615.19 PRP77652.1 - 3.7e-12 46.6 1.9 3.7e-12 46.6 1.9 2.0 2 0 0 2 2 2 1 Regulator of G protein signaling domain GPS PF01825.21 PRP77652.1 - 3.8e-06 27.3 2.6 1e-05 25.9 2.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif RasGEF_N PF00618.20 PRP77652.1 - 0.011 15.9 0.1 0.074 13.3 0.0 2.5 2 0 0 2 2 2 0 RasGEF N-terminal motif EGF_2 PF07974.13 PRP77655.1 - 0.012 15.9 6.7 0.023 15.0 6.7 1.4 1 0 0 1 1 1 0 EGF-like domain AdoHcyase PF05221.17 PRP77655.1 - 0.09 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Pkinase PF00069.25 PRP77656.1 - 3.9e-67 226.4 0.0 5.1e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77656.1 - 1.7e-26 93.1 0.0 4.9e-26 91.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP77656.1 - 0.01 15.8 1.5 0.034 14.1 0.2 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP77656.1 - 0.025 13.9 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 PRP77656.1 - 0.088 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 eRF1_2 PF03464.15 PRP77657.1 - 9.9e-44 148.9 0.1 1.8e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 PRP77657.1 - 1.9e-36 125.0 0.1 4.2e-36 123.9 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 PRP77657.1 - 2.7e-19 69.5 0.0 5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 PRP77657.1 - 2.4e-09 37.6 0.0 4.2e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 PRP77657.1 - 1.4e-08 35.1 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Pkinase PF00069.25 PRP77659.1 - 1.6e-56 191.6 0.0 1.9e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77659.1 - 1.5e-30 106.3 0.0 2e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP77659.1 - 1.3e-07 31.8 0.1 0.0071 16.3 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP77659.1 - 2.4e-06 27.1 0.0 3.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP77659.1 - 0.00033 20.1 0.1 0.00051 19.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP77659.1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Inhibitor_Mig-6 PF11555.8 PRP77659.1 - 0.06 13.4 0.7 8.9 6.5 0.2 2.4 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 zf-RING_2 PF13639.6 PRP77660.1 - 3.7e-07 30.4 10.1 1.1e-06 28.9 10.1 1.9 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 PRP77660.1 - 5.2e-05 23.3 6.7 0.00016 21.8 6.7 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 PRP77660.1 - 0.00019 21.4 3.1 0.00047 20.1 3.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Cnd1 PF12717.7 PRP77660.1 - 0.00051 20.1 3.7 0.76 9.8 0.0 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP77660.1 - 0.0016 18.5 1.1 25 5.5 0.0 5.4 4 1 1 5 5 5 0 HEAT repeat zf-rbx1 PF12678.7 PRP77660.1 - 0.0055 17.0 9.8 0.02 15.2 9.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain RIX1 PF08167.12 PRP77660.1 - 0.011 15.5 5.7 0.017 14.9 0.1 3.7 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis TetR_C_30 PF17939.1 PRP77660.1 - 0.014 15.6 0.0 0.059 13.6 0.0 2.0 2 0 0 2 2 1 0 Tetracyclin repressor-like, C-terminal domain RINGv PF12906.7 PRP77660.1 - 0.054 13.6 6.8 0.13 12.4 6.8 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 PRP77660.1 - 0.056 13.3 7.1 0.12 12.3 7.1 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 PRP77660.1 - 0.089 12.7 6.9 0.24 11.3 6.9 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 PRP77660.1 - 0.24 11.8 6.1 0.6 10.5 6.1 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 PRP77660.1 - 0.34 10.8 16.2 0.044 13.7 10.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP77660.1 - 1.4 8.9 15.0 0.26 11.2 10.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PRP77660.1 - 2.5 8.0 7.7 7.5 6.4 7.7 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PRP77660.1 - 2.7 7.9 7.1 7.6 6.5 7.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PRP77660.1 - 3.8 7.2 5.8 9 6.0 5.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ApoLp-III PF07464.11 PRP77660.1 - 5.8 7.0 6.5 0.88 9.7 0.1 2.9 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Peptidase_M41 PF01434.18 PRP77661.1 - 1.6e-63 214.1 0.1 2.8e-63 213.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PRP77661.1 - 1e-42 145.7 0.0 2.1e-42 144.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP77661.1 - 1.6e-12 47.0 0.1 3.9e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 PRP77661.1 - 0.0006 20.1 0.0 0.0042 17.4 0.0 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_2 PF07724.14 PRP77661.1 - 0.0018 18.4 0.0 0.0018 18.4 0.0 2.6 2 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 PRP77661.1 - 0.0026 17.5 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PRP77661.1 - 0.0041 17.1 0.2 0.024 14.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP77661.1 - 0.015 15.6 1.2 0.87 9.9 0.1 3.5 2 1 1 4 4 4 0 AAA domain AAA_17 PF13207.6 PRP77661.1 - 0.021 15.2 0.0 0.021 15.2 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.6 PRP77661.1 - 0.036 14.5 0.4 0.39 11.1 0.2 2.4 1 1 1 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 PRP77661.1 - 0.12 11.7 0.4 0.48 9.8 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PRP77661.1 - 0.17 11.6 0.2 0.38 10.5 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 PRP77661.1 - 0.77 10.0 4.1 1.1 9.5 0.0 2.8 2 1 0 3 3 3 0 AAA domain AAA_11 PF13086.6 PRP77661.1 - 1.1 9.0 11.1 7.6 6.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain Thioredoxin PF00085.20 PRP77662.1 - 1.2e-18 67.0 0.2 2.2e-18 66.1 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin TPR_20 PF14561.6 PRP77662.1 - 7.5e-18 64.7 2.7 1.4e-16 60.6 0.0 3.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP77662.1 - 1.2e-09 38.5 0.4 0.00027 21.4 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4795 PF16043.5 PRP77662.1 - 0.006 16.2 0.7 0.012 15.2 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Thioredoxin_2 PF13098.6 PRP77662.1 - 0.0097 16.4 0.1 0.056 13.9 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PRP77662.1 - 0.02 15.2 0.1 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like ATP13 PF12921.7 PRP77662.1 - 0.022 14.6 0.0 5.8 6.8 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ATPase expression TPR_21 PF09976.9 PRP77662.1 - 0.066 12.9 1.2 0.14 11.9 0.3 1.8 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain OST3_OST6 PF04756.13 PRP77662.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TPR_6 PF13174.6 PRP77662.1 - 0.17 12.6 0.1 10 7.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SH2 PF00017.24 PRP77663.1 - 1.1e-11 44.7 0.0 3e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 SH2 domain 7tm_2 PF00002.24 PRP77664.1 - 7.1e-12 45.1 18.0 9.6e-12 44.7 18.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 PRP77664.1 - 4.2e-05 23.5 1.2 4.2e-05 23.5 1.2 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term ADH_N PF08240.12 PRP77665.1 - 1.1e-24 86.3 5.0 2.1e-24 85.5 5.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PRP77665.1 - 2.5e-18 66.3 0.0 6.9e-18 64.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP77665.1 - 3.5e-08 34.6 0.0 5.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 PRP77665.1 - 0.0014 18.1 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 PRP77665.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 PRP77665.1 - 0.12 13.3 0.0 0.68 10.8 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 PRP77666.1 - 3.1e-48 164.5 51.6 1.6e-45 155.6 51.4 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PRP77666.1 - 6.7e-12 44.6 15.1 1.1e-11 43.9 15.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 PRP77666.1 - 8.6e-12 44.6 13.6 8.6e-12 44.6 13.6 3.7 2 2 1 3 3 3 1 Sugar (and other) transporter CcmD PF04995.14 PRP77666.1 - 0.22 11.6 0.0 0.22 11.6 0.0 3.0 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Adipogenin PF15202.6 PRP77666.1 - 0.33 11.0 4.5 13 5.9 0.5 3.4 3 0 0 3 3 3 0 Adipogenin Jiraiya PF15038.6 PRP77666.1 - 0.75 9.2 6.3 1.2 8.5 3.5 2.8 3 0 0 3 3 3 0 Jiraiya RhoGAP PF00620.27 PRP77668.1 - 6.4e-37 126.7 2.8 4e-36 124.1 0.1 2.9 2 0 0 2 2 2 1 RhoGAP domain BAR_3 PF16746.5 PRP77668.1 - 1.2e-05 25.2 10.8 1.2e-05 25.2 10.8 2.7 2 0 0 2 2 2 1 BAR domain of APPL family BAR_2 PF10455.9 PRP77668.1 - 0.0046 16.1 8.4 0.0046 16.1 8.4 2.8 2 1 1 3 3 3 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF4709 PF15821.5 PRP77668.1 - 0.33 11.2 7.6 20 5.5 0.1 4.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4709) Mnd1 PF03962.15 PRP77668.1 - 6.3 7.2 7.1 2.5 8.4 0.2 3.3 3 0 0 3 3 3 0 Mnd1 HTH domain Gly_kinase PF02595.15 PRP77669.1 - 1.7e-99 333.3 0.2 2e-99 333.1 0.2 1.0 1 0 0 1 1 1 1 Glycerate kinase family FAD_binding_4 PF01565.23 PRP77670.1 - 2.9e-17 62.7 1.6 5.8e-17 61.7 1.6 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 PRP77670.1 - 5.1e-17 61.7 0.6 9.3e-17 60.9 0.6 1.5 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_15 PF00723.21 PRP77671.1 - 1.6e-46 159.1 0.0 4.2e-44 151.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF1412 PF07203.11 PRP77671.1 - 0.051 13.8 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) UCH PF00443.29 PRP77672.1 - 1.3e-37 129.7 0.1 1.3e-37 129.7 0.1 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase PHD PF00628.29 PRP77672.1 - 1.9e-12 46.9 7.2 1.9e-12 46.9 7.2 2.1 2 0 0 2 2 2 1 PHD-finger PWWP PF00855.17 PRP77672.1 - 2.7e-11 43.7 0.2 2.7e-11 43.7 0.2 2.7 2 1 0 2 2 2 1 PWWP domain zf-rbx1 PF12678.7 PRP77672.1 - 0.43 10.9 9.4 0.34 11.2 4.7 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain V_ATPase_I PF01496.19 PRP77672.1 - 1.2 6.9 9.5 2 6.3 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PHD_2 PF13831.6 PRP77672.1 - 1.8 8.2 5.7 0.21 11.2 0.8 2.1 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 PRP77672.1 - 2.8 7.9 8.2 0.1 12.5 1.6 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PA26 PF04636.13 PRP77672.1 - 4.7 6.0 8.7 8.6 5.2 8.7 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ADK_lid PF05191.14 PRP77672.1 - 8 6.5 10.2 0.059 13.4 1.1 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF1115 PF06544.12 PRP77673.1 - 4.8e-10 39.7 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF3197 PF11432.8 PRP77673.1 - 0.019 14.9 0.2 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) Xin PF08043.12 PRP77673.1 - 0.31 10.7 1.4 0.66 9.7 0.2 2.1 2 0 0 2 2 2 0 Xin repeat Ras PF00071.22 PRP77674.1 - 1.2e-43 148.5 0.4 1.5e-43 148.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP77674.1 - 4e-27 94.8 0.3 8.5e-27 93.8 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 PRP77674.1 - 2.9e-12 46.5 0.4 1.5e-11 44.2 0.4 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 PRP77674.1 - 2.6e-11 43.3 0.3 3.5e-11 42.9 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP77674.1 - 8.9e-07 28.5 0.1 1.2e-06 28.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP77674.1 - 1.4e-05 25.1 0.4 3.1e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP77674.1 - 0.00012 22.0 1.0 0.22 11.4 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 PRP77674.1 - 0.035 14.1 0.5 0.086 12.9 0.5 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Glyco_hydro_47 PF01532.20 PRP77676.1 - 3.3e-105 352.6 0.0 5.3e-105 352.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1178 PF06676.11 PRP77676.1 - 0.11 12.9 4.3 0.18 12.2 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Ras PF00071.22 PRP77677.1 - 3.3e-52 176.4 0.0 5.2e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Ras family DUF4539 PF15072.6 PRP77677.1 - 4.7e-24 84.2 0.1 9e-24 83.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Roc PF08477.13 PRP77677.1 - 1.1e-21 77.2 0.0 2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP77677.1 - 9.8e-08 31.6 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family tRNA_anti-codon PF01336.25 PRP77677.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Gtr1_RagA PF04670.12 PRP77677.1 - 0.085 12.2 0.0 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Homeodomain PF00046.29 PRP77678.1 - 6.6e-14 51.5 1.4 1.8e-13 50.1 1.4 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP77678.1 - 0.0003 20.6 0.2 0.0011 18.8 0.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 PRP77678.1 - 0.04 13.4 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DEAD PF00270.29 PRP77679.1 - 3.3e-21 75.8 0.0 1.6e-20 73.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP77679.1 - 4.3e-17 62.6 3.3 2.4e-14 53.7 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP77679.1 - 3.5e-05 24.1 0.0 0.00025 21.4 0.0 2.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1831 PF08866.10 PRP77680.1 - 0.018 15.5 0.2 4 7.9 0.1 2.1 2 0 0 2 2 2 0 Putative amino acid metabolism Chlam_PMP PF02415.17 PRP77680.1 - 0.043 14.3 1.1 2.7 8.7 0.0 2.6 2 1 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Big_3_5 PF16640.5 PRP77680.1 - 0.085 13.0 3.1 0.12 12.6 3.1 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Lactamase_B_2 PF12706.7 PRP77681.1 - 7.5e-19 68.0 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PRP77681.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Translat_reg PF01818.17 PRP77681.1 - 0.057 13.4 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage translational regulator DnaJ_C PF01556.18 PRP77682.1 - 7.3e-40 136.5 4.2 9.9e-40 136.0 4.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PRP77682.1 - 8.3e-26 89.9 3.0 1.9e-25 88.8 3.0 1.6 1 0 0 1 1 1 1 DnaJ domain Rab5ip PF07019.12 PRP77683.1 - 7.3e-12 45.7 6.0 3e-11 43.8 6.9 1.6 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) DUF2306 PF10067.9 PRP77683.1 - 0.11 12.7 0.3 0.2 11.9 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Mitoc_mL59 PF18126.1 PRP77684.1 - 1.2e-10 41.8 2.4 1.2e-10 41.8 2.4 2.7 2 1 0 2 2 2 1 Mitochondrial ribosomal protein mL59 CR6_interact PF10147.9 PRP77684.1 - 0.0011 18.7 3.2 0.0011 18.7 3.2 2.2 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 MFS_1_like PF12832.7 PRP77685.1 - 1.7e-61 208.2 15.6 2.7e-61 207.5 15.6 1.3 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 PRP77685.1 - 8.9e-25 87.3 28.7 8.9e-25 87.3 28.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 PRP77685.1 - 3.1e-09 36.1 11.1 6.1e-09 35.2 11.1 1.4 1 1 0 1 1 1 1 LacY proton/sugar symporter AAA_28 PF13521.6 PRP77686.1 - 4.8e-29 101.7 0.4 2.4e-28 99.4 0.4 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PRP77686.1 - 6e-05 22.9 0.0 0.0067 16.2 0.0 2.2 1 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 PRP77686.1 - 0.00061 20.3 0.0 0.00087 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 PRP77686.1 - 0.0018 17.8 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA PF00004.29 PRP77686.1 - 0.0018 18.7 0.0 1 9.8 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 PRP77686.1 - 0.0049 16.8 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 PRP77686.1 - 0.012 15.7 0.0 0.056 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PRP77686.1 - 0.014 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 PRP77686.1 - 0.061 13.2 0.2 0.42 10.5 0.1 2.0 2 0 0 2 2 2 0 NACHT domain dNK PF01712.19 PRP77686.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_16 PF13191.6 PRP77686.1 - 0.085 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PRP77686.1 - 0.09 13.3 0.0 0.13 12.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 PRP77686.1 - 0.092 13.1 0.3 0.12 12.7 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PRP77686.1 - 0.093 13.0 0.0 0.88 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 PRP77686.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit cobW PF02492.19 PRP77686.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 PRP77686.1 - 0.12 11.6 0.0 0.29 10.4 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 PRP77686.1 - 0.13 12.6 0.9 0.72 10.3 1.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 PRP77686.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 PRP77686.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DAP3 PF10236.9 PRP77686.1 - 0.18 10.9 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Pkinase PF00069.25 PRP77687.1 - 2.7e-53 181.0 0.0 3.3e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77687.1 - 3.8e-26 91.9 0.0 5.9e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP77687.1 - 6.6e-07 29.5 0.7 0.012 15.5 0.2 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP77687.1 - 1.5e-06 27.7 0.0 2.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP77687.1 - 3.8e-06 25.9 0.6 6.2e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 PRP77687.1 - 1.8e-05 24.4 0.1 4.3e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.11 PRP77687.1 - 0.00025 20.2 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 PRP77687.1 - 0.00028 20.3 0.1 0.0027 17.1 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 PRP77687.1 - 0.0073 15.9 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) DUF3932 PF13068.6 PRP77687.1 - 0.0087 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3932) FTA2 PF13095.6 PRP77687.1 - 0.012 15.2 0.2 1.3 8.6 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PRP77687.1 - 0.03 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF2236 PF09995.9 PRP77689.1 - 1.5e-07 31.9 0.0 2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) GAF_2 PF13185.6 PRP77690.1 - 8.2e-08 32.6 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PRP77690.1 - 2.8e-07 31.2 0.0 3.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PRP77690.1 - 0.066 13.6 0.0 0.14 12.5 0.0 1.5 1 1 1 2 2 2 0 GAF domain DUF3684 PF12449.8 PRP77691.1 - 1.5e-109 367.4 13.5 2e-68 231.2 0.0 4.7 3 2 1 4 4 4 3 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 PRP77691.1 - 1.1e-08 35.1 0.0 2.7e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 PRP77691.1 - 2.8e-07 30.9 0.0 5.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PRP77691.1 - 2.5e-05 24.9 0.0 7.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PRP77691.1 - 0.0001 22.7 0.0 0.00019 21.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain HATPase_c PF02518.26 PRP77691.1 - 0.00082 19.9 0.0 0.0036 17.8 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rad60-SLD PF11976.8 PRP77691.1 - 0.017 15.0 0.1 0.065 13.1 0.1 2.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like WLM PF08325.10 PRP77691.1 - 0.089 12.9 0.6 0.29 11.2 0.6 1.8 1 0 0 1 1 1 0 WLM domain SLX9 PF15341.6 PRP77691.1 - 0.41 11.1 4.7 18 5.7 0.4 3.5 3 0 0 3 3 3 0 Ribosome biogenesis protein SLX9 AtuA PF07287.11 PRP77693.1 - 3.4e-110 368.1 0.1 4.4e-110 367.7 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Homeodomain PF00046.29 PRP77694.1 - 8e-20 70.4 0.6 1.3e-19 69.8 0.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP77694.1 - 6.7e-05 22.7 0.3 0.00014 21.7 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Sigma70_r4 PF04545.16 PRP77694.1 - 0.036 13.6 0.1 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 TusA PF01206.17 PRP77694.1 - 0.095 12.5 0.0 0.34 10.8 0.0 1.8 1 1 1 2 2 2 0 Sulfurtransferase TusA TM2 PF05154.16 PRP77695.1 - 2.2e-14 53.5 7.7 6.4e-14 52.0 7.7 1.7 1 0 0 1 1 1 1 TM2 domain C1_2 PF03107.16 PRP77696.1 - 0.024 15.0 0.3 0.048 14.0 0.3 1.5 1 0 0 1 1 1 0 C1 domain Metal_resist PF13801.6 PRP77696.1 - 0.07 13.3 0.8 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance DUF3782 PF12644.7 PRP77696.1 - 0.098 12.8 1.5 0.13 12.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) GAT PF03127.14 PRP77696.1 - 0.11 12.8 1.7 0.2 12.0 1.7 1.5 1 0 0 1 1 1 0 GAT domain Guanylate_cyc PF00211.20 PRP77698.1 - 4.5e-15 55.7 0.0 1.3e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1990 PF09348.10 PRP77699.1 - 3.8e-43 147.2 0.2 5e-43 146.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) Hamartin PF04388.12 PRP77700.1 - 1 7.9 17.2 1.1 7.9 17.2 1.2 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 PRP77700.1 - 6.1 6.7 26.5 9 6.2 26.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRAL_TRIO PF00650.20 PRP77701.1 - 1.9e-30 105.7 0.0 3.1e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP77701.1 - 0.0075 16.4 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ALAD PF00490.21 PRP77702.1 - 1.4e-121 405.6 0.0 1.6e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase DOMON PF03351.17 PRP77703.1 - 1e-27 96.8 0.9 1e-27 96.8 0.9 2.5 2 0 0 2 2 2 1 DOMON domain Peptidase_S9 PF00326.21 PRP77703.1 - 5.8e-09 35.7 0.2 1.7e-08 34.2 0.2 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 PRP77703.1 - 1.8e-07 30.9 0.1 3.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 PRP77703.1 - 2.4e-05 24.1 0.0 0.00035 20.3 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 PRP77703.1 - 9.4e-05 22.3 0.1 0.00023 21.0 0.1 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 PRP77703.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Bac_rhamnosid_C PF17390.2 PRP77703.1 - 0.018 14.8 0.1 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain Abhydrolase_3 PF07859.13 PRP77703.1 - 0.03 14.2 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3149 PF11346.8 PRP77704.1 - 0.064 12.9 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) TIL PF01826.17 PRP77704.1 - 5.1 7.4 13.7 40 4.6 13.7 2.1 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain EAP30 PF04157.16 PRP77705.1 - 7.6e-67 225.0 2.0 1.8e-66 223.8 1.1 2.0 2 0 0 2 2 2 1 EAP30/Vps36 family MAM33 PF02330.16 PRP77705.1 - 7.8e-06 26.0 5.1 1.7e-05 24.8 5.1 1.6 1 0 0 1 1 1 1 Mitochondrial glycoprotein Phe_tRNA-synt_N PF02912.18 PRP77705.1 - 1.4 8.9 8.7 0.34 10.9 0.9 2.5 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain SprT-like PF10263.9 PRP77706.1 - 7.7e-27 93.4 0.1 2.1e-26 92.0 0.0 1.7 1 1 1 2 2 2 1 SprT-like family DUF1609 PF07753.11 PRP77707.1 - 0.26 10.8 1.4 0.36 10.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) eRF1_1 PF03463.15 PRP77708.1 - 1.6e-48 163.9 0.4 3e-48 163.1 0.4 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 PRP77708.1 - 5.9e-31 107.5 0.1 1.1e-30 106.7 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 PRP77708.1 - 4.8e-23 81.8 0.0 1e-22 80.8 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 LppX_LprAFG PF07161.13 PRP77708.1 - 0.13 12.1 0.0 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 LppX_LprAFG lipoprotein APG6 PF04111.12 PRP77709.1 - 2.8e-37 128.4 0.0 1.6e-36 126.0 0.0 2.1 1 1 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 PRP77709.1 - 1.2e-06 29.0 9.8 2.1e-06 28.3 8.6 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF4326 PF14216.6 PRP77709.1 - 0.02 15.6 0.5 0.32 11.8 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4326) LRR_4 PF12799.7 PRP77710.1 - 4.1e-10 39.7 10.3 0.00018 21.8 0.2 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP77710.1 - 5.6e-09 35.6 5.0 0.00072 19.3 1.8 2.6 2 1 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 PRP77710.1 - 5.5e-07 29.2 0.2 2.3e-05 24.0 0.1 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 PRP77710.1 - 0.0007 19.4 0.3 0.046 13.8 0.1 2.5 2 0 0 2 2 2 1 Leucine Rich repeat LRR_1 PF00560.33 PRP77710.1 - 0.01 16.2 0.6 0.38 11.5 0.1 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat PP_kinase_N PF13089.6 PRP77710.1 - 0.01 16.1 0.3 0.049 14.0 0.0 2.1 3 0 0 3 3 3 0 Polyphosphate kinase N-terminal domain FNIP PF05725.12 PRP77710.1 - 0.57 10.4 3.2 5.4 7.3 1.4 2.3 2 0 0 2 2 2 0 FNIP Repeat RCC1 PF00415.18 PRP77711.1 - 2.2e-15 57.0 8.6 0.023 15.3 0.0 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP77711.1 - 4.8e-15 54.9 20.6 5.6e-05 22.8 0.1 6.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 PRP77711.1 - 7.9e-10 38.4 2.1 1.4e-09 37.6 2.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP77711.1 - 1.9e-08 34.1 0.8 3.7e-08 33.1 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 PRP77711.1 - 0.13 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 F-box Med11 PF10280.9 PRP77712.1 - 0.00024 21.5 4.2 0.00032 21.2 4.0 1.5 1 1 0 1 1 1 1 Mediator complex protein DHR10 PF18595.1 PRP77712.1 - 0.0044 17.1 4.2 0.011 15.8 4.2 1.8 1 1 0 1 1 1 1 Designed helical repeat protein 10 domain Tti2 PF10521.9 PRP77712.1 - 0.076 12.5 0.5 0.12 11.9 0.5 1.2 1 0 0 1 1 1 0 Tti2 family Ribosomal_L6e PF01159.19 PRP77712.1 - 0.14 12.7 0.3 0.14 12.7 0.3 1.9 2 1 0 2 2 2 0 Ribosomal protein L6e Laminin_II PF06009.12 PRP77712.1 - 0.21 11.6 3.4 0.31 11.1 1.6 1.9 1 1 1 2 2 2 0 Laminin Domain II BORCS7 PF16088.5 PRP77713.1 - 1.6e-11 44.4 3.0 1.8e-11 44.2 3.0 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 Fzo_mitofusin PF04799.13 PRP77713.1 - 0.0098 15.4 1.3 0.012 15.2 1.1 1.3 1 1 0 1 1 1 1 fzo-like conserved region CHDCT2 PF08074.11 PRP77713.1 - 0.059 13.5 0.7 0.076 13.2 0.7 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF745 PF05335.13 PRP77713.1 - 0.075 12.8 0.4 0.097 12.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ABC_membrane_2 PF06472.15 PRP77715.1 - 2.3e-68 230.6 1.6 3.6e-68 229.9 1.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 Ras PF00071.22 PRP77715.1 - 6.8e-51 172.1 6.7 3.7e-36 124.2 0.1 3.2 4 0 0 4 4 3 2 Ras family Roc PF08477.13 PRP77715.1 - 7.4e-27 94.0 6.7 1.2e-12 48.1 0.0 4.1 4 0 0 4 4 3 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 PRP77715.1 - 2.1e-12 47.7 0.0 2.7e-11 44.2 0.0 2.6 2 1 0 2 2 2 1 ABC transporter Arf PF00025.21 PRP77715.1 - 5.6e-08 32.4 3.6 1.5e-07 31.0 0.9 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_29 PF13555.6 PRP77715.1 - 9.7e-05 22.0 0.0 0.0041 16.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PRP77715.1 - 0.00026 21.0 0.3 0.024 14.7 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 PRP77715.1 - 0.00075 19.4 0.5 0.013 15.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PRP77715.1 - 0.00084 19.8 0.0 0.57 10.5 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PRP77715.1 - 0.0011 19.0 0.8 1.3 8.9 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 PRP77715.1 - 0.0018 17.8 0.2 1.2 8.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 PRP77715.1 - 0.0024 17.6 0.9 0.42 10.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 PRP77715.1 - 0.0031 17.0 1.0 0.11 11.9 0.1 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain TniB PF05621.11 PRP77715.1 - 0.0099 15.3 0.1 0.28 10.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein SRPRB PF09439.10 PRP77715.1 - 0.011 15.2 0.1 3.9 6.9 0.0 3.4 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 PRP77715.1 - 0.013 16.0 0.0 0.67 10.5 0.0 3.2 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 PRP77715.1 - 0.029 13.7 0.4 2.8 7.2 0.1 3.0 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 PRP77715.1 - 0.063 13.6 0.0 14 5.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PRP77715.1 - 0.094 13.2 0.1 0.094 13.2 0.1 2.9 3 1 0 3 3 2 0 AAA domain Lactate_perm PF02652.14 PRP77715.1 - 0.1 11.3 0.2 0.2 10.4 0.2 1.4 1 0 0 1 1 1 0 L-lactate permease AAA_28 PF13521.6 PRP77715.1 - 0.12 12.7 0.0 19 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PRP77715.1 - 0.12 11.4 0.2 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 PRP77715.1 - 0.17 11.8 1.5 25 4.7 0.1 3.1 3 0 0 3 3 3 0 NTPase FeoB_N PF02421.18 PRP77715.1 - 0.68 9.4 4.8 2.5 7.6 2.2 2.9 2 1 0 2 2 2 0 Ferrous iron transport protein B Cwf_Cwc_15 PF04889.12 PRP77716.1 - 0.038 13.7 3.8 0.073 12.8 3.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BBS1 PF14779.6 PRP77716.1 - 0.12 11.7 1.2 0.36 10.2 0.2 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 COMM_domain PF07258.14 PRP77716.1 - 0.15 12.2 0.5 2 8.6 0.1 2.4 2 0 0 2 2 2 0 COMM domain DUF2695 PF10905.8 PRP77717.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Dopey_N PF04118.14 PRP77720.1 - 2.4e-87 292.9 4.7 4.3e-85 285.5 1.6 4.2 3 1 0 3 3 3 2 Dopey, N-terminal YojJ PF10372.9 PRP77720.1 - 0.62 10.2 2.8 1.7 8.8 0.7 2.9 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Calcipressin PF04847.12 PRP77721.1 - 1.4e-07 31.4 4.6 1.4e-07 31.4 4.6 1.6 1 1 1 2 2 2 1 Calcipressin RCC1 PF00415.18 PRP77722.1 - 7.6e-38 128.9 13.2 1.6e-09 38.2 0.1 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP77722.1 - 7.3e-11 41.6 29.8 3.1e-06 26.8 2.5 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S11 PF00411.19 PRP77723.1 - 8.2e-47 158.2 0.6 1e-46 157.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 PRP77723.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Dus PF01207.17 PRP77724.1 - 1.8e-55 188.3 0.8 5.1e-55 186.7 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 PRP77724.1 - 0.0011 18.8 6.7 0.0011 18.8 6.7 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP77724.1 - 0.0041 17.1 4.9 0.0041 17.1 4.9 1.9 2 0 0 2 2 2 1 Zinc finger domain RNA_polI_A34 PF08208.11 PRP77724.1 - 3.4 7.7 37.1 0.13 12.3 23.1 2.8 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF3958 PF13125.6 PRP77725.1 - 0.98 9.7 11.3 3 8.1 11.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Jnk-SapK_ap_N PF09744.9 PRP77725.1 - 1.8 8.8 11.0 0.47 10.7 5.4 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Syntaxin PF00804.25 PRP77725.1 - 1.9 8.1 11.3 0.2 11.3 3.8 2.1 2 0 0 2 2 2 0 Syntaxin Ribosomal_S19 PF00203.21 PRP77726.1 - 1.4e-31 108.1 0.4 1.9e-31 107.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 CLP_protease PF00574.23 PRP77727.1 - 0.04 13.8 0.1 0.073 13.0 0.0 1.4 2 0 0 2 2 2 0 Clp protease Syja_N PF02383.18 PRP77728.1 - 5.6e-49 167.2 0.0 1.1e-48 166.2 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain FYVE PF01363.21 PRP77728.1 - 1e-05 25.6 7.0 2.1e-05 24.6 7.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 PRP77728.1 - 0.23 11.7 4.4 0.27 11.5 2.3 2.2 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain YchF-GTPase_C PF06071.13 PRP77729.1 - 4.1e-37 126.2 0.3 1e-36 124.9 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 PRP77729.1 - 5.2e-22 78.1 0.0 1.5e-21 76.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ANAPC5 PF12862.7 PRP77729.1 - 1.6e-15 56.9 0.0 6.2e-15 55.0 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 FeoB_N PF02421.18 PRP77729.1 - 1.7e-07 30.9 0.1 1.7e-06 27.6 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B TPR_12 PF13424.6 PRP77729.1 - 0.00049 20.3 0.4 0.47 10.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP77729.1 - 0.00072 19.0 0.2 0.014 14.8 0.1 2.4 3 0 0 3 3 3 1 MalT-like TPR region TPR_4 PF07721.14 PRP77729.1 - 0.056 14.1 0.0 35 5.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MeaB PF03308.16 PRP77729.1 - 0.14 11.1 0.0 0.32 9.9 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TPR_19 PF14559.6 PRP77729.1 - 0.19 12.3 0.0 24 5.5 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Lustrin_cystein PF14625.6 PRP77733.1 - 0.05 14.0 1.2 0.05 14.0 1.2 3.2 2 1 1 3 3 3 0 Lustrin, cysteine-rich repeated domain Pox_A6 PF04924.12 PRP77735.1 - 0.062 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A6 protein UIM PF02809.20 PRP77737.1 - 0.19 11.7 0.9 0.38 10.8 0.9 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif CPDase PF07823.11 PRP77738.1 - 2.6e-10 40.4 0.0 6.1e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 PRP77738.1 - 0.0089 15.9 0.0 0.029 14.3 0.0 1.7 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily RSN1_7TM PF02714.15 PRP77739.1 - 0.00085 18.7 1.5 0.0082 15.5 0.1 2.4 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate Doppel PF11466.8 PRP77739.1 - 0.078 12.7 2.3 0.11 12.1 0.7 2.3 2 0 0 2 2 2 0 Prion-like protein Doppel DUF5345 PF17280.2 PRP77739.1 - 0.16 12.0 3.0 0.21 11.6 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) 7tm_3 PF00003.22 PRP77739.1 - 0.62 9.7 13.5 4.7 6.9 12.2 2.5 2 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Ank_2 PF12796.7 PRP77741.1 - 2.5e-10 40.8 0.3 0.00054 20.5 0.0 3.5 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP77741.1 - 4.6e-07 29.6 0.7 12 6.8 0.0 6.8 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 PRP77741.1 - 3.3e-06 27.5 3.3 0.77 10.4 0.1 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP77741.1 - 3.3e-06 27.2 0.1 0.21 12.0 0.0 4.8 3 2 2 5 5 5 1 Ankyrin repeats (many copies) F-box PF00646.33 PRP77741.1 - 0.01 15.7 0.1 0.01 15.7 0.1 2.6 3 0 0 3 3 3 0 F-box domain FAT PF02259.23 PRP77741.1 - 0.027 13.7 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 FAT domain F-box-like PF12937.7 PRP77741.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like Helicase_C_2 PF13307.6 PRP77742.1 - 3.7e-53 180.2 0.1 2.4e-52 177.6 0.0 2.5 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.15 PRP77742.1 - 1.2e-52 178.1 1.3 1.2e-52 178.1 1.3 2.5 1 1 1 2 2 2 1 DEAD_2 ResIII PF04851.15 PRP77742.1 - 5.1e-05 23.3 3.3 0.36 10.8 0.4 3.5 2 2 1 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.29 PRP77742.1 - 0.01 15.6 0.8 1.4 8.7 0.3 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.16 PRP77742.1 - 0.011 15.2 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein DUF883 PF05957.13 PRP77742.1 - 0.19 12.4 4.7 0.43 11.2 2.9 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PNISR PF15996.5 PRP77742.1 - 4.3 7.6 16.1 11 6.2 16.1 1.7 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR RasGEF PF00617.19 PRP77743.1 - 6.7e-91 303.3 9.0 3.7e-56 190.1 0.1 3.3 4 0 0 4 4 4 2 RasGEF domain RasGEF_N PF00618.20 PRP77743.1 - 3.8e-45 152.4 14.3 8.1e-24 83.9 1.1 3.7 5 0 0 5 5 5 2 RasGEF N-terminal motif CBM_2 PF00553.19 PRP77743.1 - 0.084 13.2 0.3 0.18 12.1 0.3 1.4 1 0 0 1 1 1 0 Cellulose binding domain dCache_3 PF14827.6 PRP77743.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase Claudin_2 PF13903.6 PRP77743.1 - 0.66 9.7 5.0 0.38 10.5 0.1 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ABC_membrane PF00664.23 PRP77744.1 - 3.3e-68 230.3 29.5 1.4e-38 133.1 0.9 2.5 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP77744.1 - 5.6e-52 175.9 0.0 2.1e-30 106.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PRP77744.1 - 4.3e-13 49.2 2.7 0.00063 19.3 0.0 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PRP77744.1 - 1.1e-06 28.8 0.8 0.17 11.6 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 PRP77744.1 - 1.7e-05 24.0 0.0 0.031 13.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 PRP77744.1 - 5.4e-05 23.2 0.3 0.1 12.7 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 PRP77744.1 - 0.00018 21.3 0.0 0.081 12.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PRP77744.1 - 0.00023 20.8 0.0 0.63 9.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP77744.1 - 0.00031 21.2 0.0 0.073 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 PRP77744.1 - 0.00035 21.1 0.0 0.13 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 PRP77744.1 - 0.0006 19.6 0.0 0.77 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 PRP77744.1 - 0.0019 18.3 0.8 1.1 9.3 0.1 2.6 2 0 0 2 2 2 1 Dynamin family DEAD PF00270.29 PRP77744.1 - 0.0038 17.0 0.2 7.3 6.3 0.1 3.5 3 1 0 3 3 3 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 PRP77744.1 - 0.0039 17.1 0.2 2.3 8.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase TrwB_AAD_bind PF10412.9 PRP77744.1 - 0.0041 16.1 0.0 1.2 8.0 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 PRP77744.1 - 0.0042 17.5 0.5 2 8.9 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP77744.1 - 0.0058 16.9 0.6 1.5 9.1 0.2 2.9 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 PRP77744.1 - 0.0076 16.0 0.1 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PRP77744.1 - 0.0084 15.6 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 PRP77744.1 - 0.016 14.8 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 PRP77744.1 - 0.018 14.9 0.5 12 5.5 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein cobW PF02492.19 PRP77744.1 - 0.026 14.1 0.4 0.39 10.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 PRP77744.1 - 0.045 13.8 1.0 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 PRP77744.1 - 0.086 12.0 0.0 2.7 7.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 PRP77744.1 - 0.12 12.6 0.2 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 PRP77744.1 - 0.12 12.0 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PRP77744.1 - 0.12 11.6 0.1 5.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 PRP77744.1 - 0.14 12.7 0.1 8.8 6.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PRP77744.1 - 0.31 10.8 2.2 18 5.0 0.0 3.1 4 0 0 4 4 4 0 IstB-like ATP binding protein Pyrophosphatase PF00719.19 PRP77746.1 - 5.7e-46 156.2 0.8 1e-45 155.4 0.8 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase Ank_2 PF12796.7 PRP77746.1 - 0.00015 22.3 0.0 0.024 15.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) DUF758 PF05527.11 PRP77746.1 - 0.0007 19.6 0.3 0.0021 18.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF758) F-box-like PF12937.7 PRP77746.1 - 0.0058 16.5 3.2 4.2 7.3 0.2 3.6 3 0 0 3 3 3 2 F-box-like Ank_3 PF13606.6 PRP77746.1 - 0.026 15.0 0.8 15 6.5 0.0 4.8 5 0 0 5 5 5 0 Ankyrin repeat DUF2235 PF09994.9 PRP77747.1 - 1.4e-77 260.9 0.0 3.2e-77 259.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Bact_lectin PF18483.1 PRP77747.1 - 6.6e-12 45.9 0.2 1.7e-11 44.5 0.2 1.6 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 PRP77747.1 - 1.2e-11 44.6 0.0 2.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Legume lectin domain CVNH PF08881.10 PRP77747.1 - 3.3e-09 37.4 0.0 1.9e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 CVNH domain WD40 PF00400.32 PRP77747.1 - 2.3e-08 34.6 15.5 0.066 14.1 1.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Lectin_leg-like PF03388.13 PRP77747.1 - 1.5e-06 27.8 0.2 3.9e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 Legume-like lectin family Dynein_IC2 PF11540.8 PRP77747.1 - 2.5e-05 24.1 0.4 6.3e-05 22.8 0.4 1.8 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 PF12894.7 PRP77747.1 - 0.00074 19.8 0.1 0.013 15.8 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DEK_C PF08766.11 PRP77750.1 - 1.4e-06 28.1 1.8 3.2e-06 26.9 1.8 1.7 1 1 0 1 1 1 1 DEK C terminal domain PC4 PF02229.16 PRP77750.1 - 5.7e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Complex1_LYR PF05347.15 PRP77751.1 - 1.2e-12 47.6 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PRP77751.1 - 0.034 14.9 0.1 0.051 14.3 0.1 1.3 1 1 0 1 1 1 0 Complex1_LYR-like HSP20 PF00011.21 PRP77752.1 - 5.9e-20 71.3 0.2 8e-20 70.9 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP77752.1 - 4.3e-06 26.2 0.0 5.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Ephrin_rec_like PF07699.13 PRP77754.1 - 6.3 6.6 11.3 3.7 7.4 1.0 3.1 1 1 2 3 3 3 0 Putative ephrin-receptor like SapB_1 PF05184.15 PRP77758.1 - 2.5e-06 27.4 5.0 2.6e-06 27.3 2.0 2.4 3 0 0 3 3 3 1 Saposin-like type B, region 1 SapB_2 PF03489.17 PRP77758.1 - 0.0014 18.7 0.5 0.0031 17.6 0.5 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 2 AlaDh_PNT_N PF05222.15 PRP77759.1 - 9e-25 87.6 0.0 1.4e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Rap_GAP PF02145.15 PRP77761.1 - 3.1e-58 196.4 0.0 6.5e-58 195.4 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP YtxH PF12732.7 PRP77761.1 - 0.64 10.6 2.4 1.6 9.3 1.2 2.2 2 0 0 2 2 2 0 YtxH-like protein zf-DBF PF07535.12 PRP77763.1 - 2.6e-16 59.5 2.3 6.1e-16 58.3 0.8 2.4 2 0 0 2 2 2 1 DBF zinc finger LIG3_BRCT PF16759.5 PRP77763.1 - 0.00014 22.1 0.1 0.0011 19.2 0.0 2.3 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 PRP77763.1 - 0.034 14.1 0.3 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 twin BRCT domain Peptidase_M1 PF01433.20 PRP77764.1 - 9e-09 35.2 0.0 8.4e-08 32.0 0.0 2.5 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PRP77764.1 - 0.00042 20.5 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 PRP77764.1 - 0.079 13.4 0.0 1.9 8.9 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats VPS9 PF02204.18 PRP77765.1 - 1.2e-33 115.4 0.0 2.2e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 PRP77765.1 - 4e-08 33.5 0.0 1.3e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) Nucleopor_Nup85 PF07575.13 PRP77765.1 - 0.038 12.6 0.2 0.083 11.4 0.2 1.5 1 0 0 1 1 1 0 Nup85 Nucleoporin NUC202 PF08166.12 PRP77765.1 - 2.7 8.2 4.4 0.79 9.8 0.1 2.3 3 0 0 3 3 3 0 NUC202 domain DUF1963 PF09234.10 PRP77767.1 - 3.4e-11 44.0 0.3 1.3e-10 42.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1963) PTPRCAP PF15713.5 PRP77767.1 - 0.22 11.8 10.6 0.4 11.0 10.6 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PPR_long PF17177.4 PRP77768.1 - 0.0046 16.4 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP BRAP2 PF07576.12 PRP77768.1 - 0.057 13.6 0.3 0.095 12.9 0.3 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 PPR_2 PF13041.6 PRP77768.1 - 0.11 12.7 0.2 0.65 10.2 0.3 2.1 1 1 1 2 2 2 0 PPR repeat family Response_reg PF00072.24 PRP77769.1 - 1.7e-14 53.9 0.3 3.4e-14 52.9 0.1 1.6 2 0 0 2 2 2 1 Response regulator receiver domain OMP_b-brl_3 PF14905.6 PRP77769.1 - 0.039 12.9 0.5 0.062 12.3 0.5 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family HATPase_c PF02518.26 PRP77769.1 - 0.082 13.4 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF577 PF04510.12 PRP77770.1 - 0.049 13.5 0.0 6.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF577) DLH PF01738.18 PRP77771.1 - 4.9e-16 58.9 0.0 6.1e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family adh_short_C2 PF13561.6 PRP77772.1 - 2e-31 109.3 0.0 2.6e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP77772.1 - 8.6e-24 84.1 0.0 1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP77772.1 - 2.2e-05 24.5 0.1 3.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP77772.1 - 0.0033 16.9 0.1 0.0058 16.1 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 PRP77772.1 - 0.038 14.4 0.0 0.31 11.5 0.1 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding RuvX PF03652.15 PRP77772.1 - 0.061 13.7 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 Holliday junction resolvase F420_oxidored PF03807.17 PRP77772.1 - 0.077 13.6 0.1 0.16 12.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sec6 PF06046.13 PRP77773.1 - 2.1e-100 336.8 6.9 2.6e-100 336.5 6.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 OSCP PF00213.18 PRP77773.1 - 0.0023 18.1 0.1 0.36 10.9 0.3 3.2 2 1 0 2 2 2 1 ATP synthase delta (OSCP) subunit NGP1NT PF08153.12 PRP77773.1 - 0.0032 17.6 1.2 8.8 6.5 0.0 3.6 3 0 0 3 3 3 2 NGP1NT (NUC091) domain HhH-GPD PF00730.25 PRP77774.1 - 0.11 12.9 0.0 3.5 8.1 0.0 3.2 2 1 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein Alpha-amylase PF00128.24 PRP77775.1 - 2.7e-16 60.0 0.0 1.2e-15 58.0 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PRP77775.1 - 2.2e-11 44.0 0.2 7.7e-11 42.3 0.2 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Pur_ac_phosph_N PF16656.5 PRP77775.1 - 0.47 11.1 4.7 0.56 10.8 0.0 3.0 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Inhibitor_Mig-6 PF11555.8 PRP77775.1 - 1.5 9.0 5.5 4.5 7.5 5.5 1.8 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 DegS PF05384.11 PRP77776.1 - 0.00068 19.2 1.6 0.00084 18.9 0.1 1.9 2 0 0 2 2 2 1 Sensor protein DegS HD_3 PF13023.6 PRP77776.1 - 0.16 11.9 0.8 0.37 10.7 0.8 1.5 1 0 0 1 1 1 0 HD domain DUF4131 PF13567.6 PRP77777.1 - 1.7 8.3 5.1 12 5.5 4.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Brix PF04427.18 PRP77779.1 - 1e-22 81.2 2.0 1.7e-14 54.4 1.2 2.3 1 1 1 2 2 2 2 Brix domain RCC1 PF00415.18 PRP77780.1 - 1.4e-16 60.8 10.0 4.4e-08 33.6 0.0 6.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat HCNGP PF07818.13 PRP77780.1 - 3.8e-15 56.3 0.1 8e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 HCNGP-like protein BTB PF00651.31 PRP77780.1 - 1.9e-14 53.8 4.9 1.2e-12 48.0 0.1 3.3 3 1 0 3 3 3 2 BTB/POZ domain RCC1_2 PF13540.6 PRP77780.1 - 1.1e-12 47.4 19.8 2.4e-05 24.0 0.1 6.4 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Filamin PF00630.19 PRP77780.1 - 8.3e-06 26.6 0.3 3.1e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Filamin/ABP280 repeat Ank_2 PF12796.7 PRP77780.1 - 0.00078 20.0 0.2 0.0095 16.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77780.1 - 0.023 15.3 1.3 0.17 12.5 0.1 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77780.1 - 0.2 12.3 0.4 47 5.0 0.1 3.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 PRP77782.1 - 0.00047 20.7 0.1 0.0059 17.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77782.1 - 0.025 15.1 0.4 2.2 8.9 0.0 3.7 4 0 0 4 4 4 0 Ankyrin repeats (many copies) PhoLip_ATPase_C PF16212.5 PRP77783.1 - 4.3e-83 278.9 20.5 4.3e-83 278.9 20.5 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP77783.1 - 3.4e-25 87.5 1.8 3.4e-25 87.5 1.8 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 PRP77783.1 - 3.5e-11 43.0 1.0 6.9e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 PRP77783.1 - 3.8e-11 42.9 0.0 2.9e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PRP77783.1 - 1.3e-07 32.1 0.8 4.1e-05 24.0 0.4 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fascin PF06268.13 PRP77784.1 - 1.9e-17 63.5 0.0 4.7e-05 23.6 0.0 4.4 1 1 3 4 4 4 4 Fascin domain RicinB_lectin_2 PF14200.6 PRP77784.1 - 3.2e-11 43.8 0.9 0.0022 18.7 0.2 4.1 1 1 4 5 5 5 5 Ricin-type beta-trefoil lectin domain-like DUF569 PF04601.13 PRP77784.1 - 5.7e-11 42.3 0.1 0.0069 16.1 0.0 3.5 1 1 3 4 4 4 4 Domain of unknown function (DUF569) FRG1 PF06229.12 PRP77784.1 - 3.2e-09 36.8 0.0 0.00011 22.0 0.0 3.8 1 1 3 4 4 4 3 FRG1-like domain Inhibitor_I66 PF16850.5 PRP77784.1 - 0.018 14.9 1.5 0.46 10.3 0.1 3.1 2 2 1 4 4 4 0 Peptidase inhibitor I66 ATG101 PF07855.12 PRP77784.1 - 5.6 6.9 7.1 8.3 6.4 0.2 2.7 2 1 1 3 3 3 0 Autophagy-related protein 101 Band_7 PF01145.25 PRP77787.1 - 5.9e-19 68.8 0.6 8e-19 68.3 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 PRP77787.1 - 0.0049 16.0 0.4 0.0066 15.5 0.4 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial RhoGAP PF00620.27 PRP77788.1 - 1.7e-40 138.3 0.1 2.7e-40 137.7 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 PRP77788.1 - 1.2e-12 47.6 2.3 1.2e-12 47.6 2.3 1.9 2 0 0 2 2 2 1 WW domain RPEL PF02755.15 PRP77788.1 - 2.4e-05 23.9 3.4 5.1e-05 22.8 3.4 1.6 1 0 0 1 1 1 1 RPEL repeat PilN PF05137.13 PRP77788.1 - 0.029 14.5 0.0 0.07 13.3 0.0 1.6 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) Exo_endo_phos PF03372.23 PRP77790.1 - 1.1e-14 54.5 0.0 1.6e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PhoH PF02562.16 PRP77790.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein BTB_2 PF02214.22 PRP77791.1 - 1.4e-15 57.4 0.0 3.3e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Aldo_ket_red PF00248.21 PRP77793.1 - 5.3e-07 29.1 0.0 8.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family CAAP1 PF15335.6 PRP77793.1 - 0.27 11.8 0.8 2.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Kinetochor_Ybp2 PF08568.10 PRP77794.1 - 2.1e-12 46.3 0.3 3.9e-09 35.6 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin SKG6 PF08693.10 PRP77794.1 - 0.048 13.1 2.1 0.14 11.6 2.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Citrate_bind PF16114.5 PRP77795.1 - 3.4e-84 280.8 0.8 5.7e-84 280.0 0.8 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 PRP77795.1 - 5.2e-21 75.1 0.0 6.6e-20 71.5 0.0 2.4 1 1 1 2 2 2 1 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 PRP77795.1 - 3.1e-13 49.8 0.0 7.2e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 PRP77795.1 - 4.4e-10 40.1 0.1 9.9e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 PRP77795.1 - 1e-06 28.5 0.0 2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 PRP77795.1 - 8e-05 22.4 0.0 0.002 17.9 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Beta_helix PF13229.6 PRP77796.1 - 6.3e-05 22.9 25.8 6.3e-05 22.9 25.8 5.0 3 2 0 3 3 3 1 Right handed beta helix region B_lectin PF01453.24 PRP77796.1 - 0.028 15.0 0.1 8 7.1 0.0 3.3 1 1 1 3 3 3 0 D-mannose binding lectin DUF3263 PF11662.8 PRP77796.1 - 0.21 11.5 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3263) PT-VENN PF04829.13 PRP77796.1 - 1.6 8.9 4.1 2.4 8.3 0.9 3.1 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif SAM_2 PF07647.17 PRP77797.1 - 1.2e-07 31.7 0.0 4.4e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP77797.1 - 1.3e-07 32.0 0.0 3.2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Esterase_phd PF10503.9 PRP77799.1 - 0.0011 18.6 0.0 0.0011 18.6 0.0 2.8 3 0 0 3 3 3 1 Esterase PHB depolymerase AXE1 PF05448.12 PRP77799.1 - 0.0057 15.4 0.0 0.019 13.7 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 PRP77799.1 - 0.027 14.0 0.1 0.19 11.2 0.1 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family RicinB_lectin_2 PF14200.6 PRP77800.1 - 1.6e-12 48.0 5.5 2.1e-11 44.4 0.2 3.1 2 1 1 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 PRP77800.1 - 0.00054 20.2 0.6 0.023 15.0 0.4 2.1 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Y_phosphatase PF00102.27 PRP77804.1 - 1.2e-72 244.3 0.1 1.6e-72 243.9 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PRP77804.1 - 5.8e-07 29.4 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PRP77804.1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family BAH PF01426.18 PRP77805.1 - 1.3e-12 47.7 0.0 2.4e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 BAH domain AT_hook PF02178.19 PRP77805.1 - 2.2e-05 23.8 44.0 0.081 12.8 2.1 4.4 4 0 0 4 4 4 4 AT hook motif RFX5_DNA_bdg PF14621.6 PRP77805.1 - 0.007 16.2 9.6 1 9.1 0.2 3.4 3 0 0 3 3 3 3 RFX5 DNA-binding domain PAS PF00989.25 PRP77806.1 - 0.0009 19.2 0.0 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 PRP77807.1 - 0.00048 20.2 11.9 0.0022 18.1 11.9 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Piwi PF02171.17 PRP77809.1 - 2.1e-49 168.4 0.0 3e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 PRP77809.1 - 5.9e-09 35.8 0.2 1.1e-08 34.9 0.2 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 PRP77809.1 - 2.8e-05 23.7 0.0 7.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 PRP77809.1 - 0.0012 19.5 0.1 0.0038 17.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute CAP59_mtransfer PF11735.8 PRP77810.1 - 1.1e-47 162.8 0.0 1.3e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Q_salvage PF10343.9 PRP77812.1 - 7.4e-102 340.7 0.0 8.6e-102 340.5 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Ribosomal_L13 PF00572.18 PRP77813.1 - 3.4e-07 30.6 0.0 8.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L13 SH2 PF00017.24 PRP77814.1 - 2.7e-25 88.3 0.0 1e-15 57.6 0.0 2.6 2 0 0 2 2 2 2 SH2 domain DUF4506 PF14958.6 PRP77814.1 - 9.1e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) Cbl_N3 PF02762.14 PRP77814.1 - 0.0001 22.1 0.0 0.048 13.5 0.0 2.5 2 0 0 2 2 2 2 CBL proto-oncogene N-terminus, SH2-like domain AAA_11 PF13086.6 PRP77814.1 - 0.0035 17.2 0.5 0.0063 16.3 0.5 1.3 1 0 0 1 1 1 1 AAA domain IBP39 PF11422.8 PRP77814.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Initiator binding protein 39 kDa V_ATPase_I PF01496.19 PRP77814.1 - 0.0071 14.3 2.0 0.033 12.1 2.0 1.8 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 PRP77814.1 - 0.19 11.8 5.1 0.58 10.2 5.1 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SDA1 PF05285.12 PRP77815.1 - 1.7e-59 202.0 52.9 1.7e-59 202.0 52.9 2.0 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 PRP77815.1 - 9.6e-21 73.9 0.3 3.3e-20 72.1 0.3 2.0 1 0 0 1 1 1 1 NUC130/3NT domain BTB PF00651.31 PRP77815.1 - 0.048 13.9 0.4 0.2 11.9 0.1 2.3 2 0 0 2 2 2 0 BTB/POZ domain Tim17 PF02466.19 PRP77816.1 - 0.0014 19.0 0.3 0.0027 18.1 0.3 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FAT PF02259.23 PRP77817.1 - 1.1e-89 301.1 0.2 1e-88 297.9 0.0 2.6 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 PRP77817.1 - 3.8e-71 239.8 0.1 1.7e-70 237.7 0.2 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 PRP77817.1 - 3.3e-48 163.6 12.1 2.2e-46 157.7 0.0 5.8 6 1 0 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 PRP77817.1 - 4.5e-41 139.3 4.2 1.2e-40 137.9 0.2 4.1 5 0 0 5 5 4 1 FKBP12-rapamycin binding domain FATC PF02260.20 PRP77817.1 - 1.2e-17 63.4 1.0 4.7e-17 61.5 0.7 2.3 2 0 0 2 2 2 1 FATC domain HEAT PF02985.22 PRP77817.1 - 1.2e-15 56.3 17.7 0.0039 17.3 0.0 11.5 12 0 0 12 12 10 3 HEAT repeat Adaptin_N PF01602.20 PRP77817.1 - 1.2e-13 50.4 13.4 5.8e-08 31.8 0.7 5.5 5 1 1 6 6 6 4 Adaptin N terminal region HEAT_2 PF13646.6 PRP77817.1 - 6.6e-13 48.9 5.7 0.017 15.5 0.0 9.2 5 3 3 9 9 9 2 HEAT repeats Cnd1 PF12717.7 PRP77817.1 - 8.7e-11 42.1 7.5 0.00015 21.8 0.0 6.7 5 2 3 8 8 8 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PRP77817.1 - 2.9e-07 30.8 10.0 0.0051 17.3 0.0 8.4 9 1 1 10 10 8 2 HEAT-like repeat UME PF08064.13 PRP77817.1 - 2.3e-06 27.4 6.1 0.49 10.3 0.2 6.7 6 1 0 6 6 6 2 UME (NUC010) domain DRIM PF07539.12 PRP77817.1 - 8.3e-05 21.1 12.3 0.076 11.3 0.7 5.8 4 2 3 7 7 7 2 Down-regulated in metastasis Sec7_N PF12783.7 PRP77817.1 - 0.0018 18.2 1.1 0.47 10.4 0.0 4.8 4 2 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Utp12 PF04003.12 PRP77817.1 - 0.005 17.1 1.4 0.049 14.0 0.1 3.5 3 0 0 3 3 2 1 Dip2/Utp12 Family Cohesin_HEAT PF12765.7 PRP77817.1 - 0.025 14.9 0.0 4.2 7.8 0.0 3.6 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 PRP77817.1 - 0.026 15.1 3.1 2.1 9.0 0.0 5.3 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region Cytomega_gL PF01801.16 PRP77817.1 - 0.063 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L RICTOR_N PF14664.6 PRP77817.1 - 0.072 12.1 5.1 0.36 9.8 0.1 3.7 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term NmrA PF05368.13 PRP77818.1 - 4.2e-20 72.3 0.0 6e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP77818.1 - 0.016 15.1 0.1 0.087 12.7 0.1 2.2 2 1 0 2 2 2 0 NAD(P)H-binding Alginate_lyase PF05426.12 PRP77820.1 - 0.00012 21.7 0.4 0.00015 21.4 0.4 1.1 1 0 0 1 1 1 1 Alginate lyase RVT_1 PF00078.27 PRP77821.1 - 1.7e-06 27.8 1.0 4.1e-06 26.5 0.2 2.2 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 PRP77822.1 - 4.4e-18 65.6 0.7 7.1e-18 64.9 0.2 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PRP77822.1 - 7.9e-13 48.3 0.1 1.5e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PRP77822.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Viral_env_E26 PF11050.8 PRP77823.1 - 0.1 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 Pkinase PF00069.25 PRP77824.1 - 3.2e-23 82.5 0.0 3.6e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77824.1 - 2.5e-05 23.7 0.0 3.6e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PRP77825.1 - 6.8e-29 97.2 10.8 7.6e-08 31.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PRP77825.1 - 8.4e-28 96.6 10.6 4.2e-14 52.7 2.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP77825.1 - 5e-26 88.4 9.9 9.2e-08 31.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PRP77825.1 - 1.4e-23 82.5 11.5 3.5e-12 46.0 1.3 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 PRP77825.1 - 1.7e-12 47.4 0.5 1e-05 25.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PRP77825.1 - 3.3e-12 45.3 9.3 2.2e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 EF hand Caleosin PF05042.13 PRP77825.1 - 3.5e-06 27.0 2.4 0.29 11.1 0.0 3.8 1 1 3 4 4 4 2 Caleosin related protein EF-hand_11 PF08976.11 PRP77825.1 - 7.9e-05 23.5 1.2 0.0015 19.3 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 PRP77825.1 - 0.00019 21.3 3.8 0.29 11.1 0.1 2.7 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PRP77825.1 - 0.0005 20.4 1.2 0.18 12.2 0.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.13 PRP77825.1 - 0.026 14.5 0.7 0.15 12.0 0.1 2.3 1 1 2 3 3 3 0 Tellurite resistance protein TerB EF-hand_14 PF17959.1 PRP77825.1 - 0.029 14.7 1.7 1.6 9.1 0.3 2.5 2 1 0 2 2 2 0 EF-hand domain DUF1403 PF07183.11 PRP77825.1 - 0.056 13.0 0.0 0.26 10.8 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1403) DUF1636 PF07845.11 PRP77825.1 - 0.056 13.9 0.0 6.2 7.3 0.0 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1636) DUF2666 PF10869.8 PRP77825.1 - 0.086 13.0 3.6 6.2 7.0 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2666) EF-hand_like PF09279.11 PRP77825.1 - 0.099 13.1 2.2 0.89 10.1 0.1 2.7 2 1 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like MgtE_N PF03448.17 PRP77825.1 - 0.14 12.8 2.5 0.31 11.7 0.4 2.3 1 1 1 2 2 2 0 MgtE intracellular N domain GPHH PF16905.5 PRP77825.1 - 0.15 11.8 0.0 1.5 8.7 0.0 2.4 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated DUF1002 PF06207.11 PRP77825.1 - 0.16 11.4 0.3 13 5.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1002) Toprim_2 PF13155.6 PRP77825.1 - 0.21 12.0 2.3 9.5 6.7 0.8 3.0 1 1 2 3 3 3 0 Toprim-like S1 PF00575.23 PRP77826.1 - 2.8e-11 43.6 0.3 5e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 PRP77826.1 - 0.00063 20.0 0.1 0.00089 19.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 PRP77826.1 - 0.00074 19.8 0.0 0.031 14.7 0.0 2.5 1 1 1 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GAGA PF09237.11 PRP77828.1 - 0.017 14.9 0.5 0.028 14.2 0.4 1.4 1 1 0 1 1 1 0 GAGA factor zf-MYND PF01753.18 PRP77830.1 - 2.2e-12 46.8 13.0 4.4e-12 45.9 13.0 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 PRP77830.1 - 1.8 8.9 10.1 5 7.5 10.1 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 PRP77830.1 - 7.9 6.7 11.6 6.2 7.0 0.4 3.2 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ax_dynein_light PF10211.9 PRP77831.1 - 8e-87 290.0 13.5 1.3e-86 289.4 13.5 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain Allexi_40kDa PF05549.11 PRP77831.1 - 0.013 15.1 1.3 0.024 14.1 0.9 1.7 1 1 0 1 1 1 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.24 PRP77831.1 - 0.11 12.5 3.5 0.18 11.7 3.5 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Spc24 PF08286.11 PRP77831.1 - 0.17 12.2 8.2 0.44 10.8 8.2 1.8 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 End3 PF12761.7 PRP77831.1 - 0.2 11.8 10.9 0.042 14.0 7.0 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF5320 PF17253.2 PRP77831.1 - 0.24 12.5 9.3 0.32 12.1 1.2 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Syntaxin-6_N PF09177.11 PRP77831.1 - 0.82 10.3 10.4 0.21 12.1 6.8 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ADIP PF11559.8 PRP77831.1 - 1.1 9.3 20.0 0.061 13.4 14.7 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 PRP77831.1 - 1.3 9.2 14.9 3.2 7.9 4.3 2.8 1 1 1 2 2 2 0 Basic region leucine zipper DUF4164 PF13747.6 PRP77831.1 - 1.8 8.9 12.1 7.7 6.9 9.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF658 PF04936.12 PRP77831.1 - 3.2 7.5 12.6 7.4 6.3 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF658) DivIC PF04977.15 PRP77831.1 - 4.6 7.1 14.8 0.059 13.1 3.2 2.9 2 1 0 3 3 3 0 Septum formation initiator FlaC_arch PF05377.11 PRP77831.1 - 6.8 7.2 9.2 31 5.1 0.2 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) EF-hand_7 PF13499.6 PRP77832.1 - 1.6e-31 108.6 10.1 3.8e-10 40.1 1.7 5.0 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 PRP77832.1 - 4e-31 104.2 13.0 2.6e-05 23.5 0.1 7.6 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 PRP77832.1 - 6.7e-27 91.1 12.6 0.00076 19.2 0.0 7.6 7 0 0 7 7 7 6 EF-hand domain Metallophos PF00149.28 PRP77832.1 - 7.1e-26 92.0 0.1 4e-25 89.5 0.1 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase EF-hand_8 PF13833.6 PRP77832.1 - 1.3e-22 79.4 10.2 0.00076 19.3 0.1 7.5 4 3 3 7 7 7 7 EF-hand domain pair EF-hand_5 PF13202.6 PRP77832.1 - 2.1e-19 68.1 10.4 0.00082 18.8 0.1 6.7 6 1 1 7 7 7 5 EF hand PPP5 PF08321.12 PRP77832.1 - 1.5e-06 28.4 0.0 3.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region EF-hand_4 PF12763.7 PRP77832.1 - 0.0024 17.8 5.2 3.1 7.8 0.3 4.3 3 2 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 PRP77832.1 - 0.017 15.9 0.2 5.1 8.0 0.1 3.1 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 PRP77832.1 - 0.025 14.9 13.6 1.7 9.0 0.1 4.2 5 0 0 5 5 4 0 Secreted protein acidic and rich in cysteine Ca binding region NYD-SP28_assoc PF14775.6 PRP77832.1 - 0.065 13.3 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain RPE65 PF03055.15 PRP77833.1 - 4.2e-106 355.9 0.4 4.9e-106 355.7 0.4 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Cag12 PF13117.6 PRP77833.1 - 0.092 13.3 0.2 2.7 8.6 0.1 2.6 2 0 0 2 2 2 0 Cag pathogenicity island protein Cag12 TetM_leader PF08076.11 PRP77833.1 - 0.13 12.1 0.3 0.34 10.7 0.3 1.7 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide RasGEF PF00617.19 PRP77834.1 - 1.9e-29 103.1 0.0 4.1e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain PAP2 PF01569.21 PRP77834.1 - 0.0095 15.7 3.7 0.027 14.2 3.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily Bap31 PF05529.12 PRP77835.1 - 3.9e-23 81.8 4.9 5.5e-23 81.3 4.9 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF4083 PF13314.6 PRP77835.1 - 0.053 13.5 0.6 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DNase_II PF03265.15 PRP77836.1 - 9.8e-87 291.2 0.2 1.3e-86 290.8 0.2 1.2 1 0 0 1 1 1 1 Deoxyribonuclease II Endonuclea_NS_2 PF13930.6 PRP77836.1 - 4.3e-09 36.6 0.0 1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease RasGEF PF00617.19 PRP77837.1 - 3.3e-37 128.4 3.4 3.3e-37 128.4 3.4 2.3 1 1 1 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP77837.1 - 5.1e-07 29.9 0.7 2.1e-06 27.9 0.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif RGCC PF15151.6 PRP77837.1 - 0.04 14.1 2.2 0.12 12.6 2.2 1.8 1 0 0 1 1 1 0 Response gene to complement 32 protein family DUF4277 PF14104.6 PRP77837.1 - 0.093 13.1 0.1 0.48 10.8 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4277) DUF3391 PF11871.8 PRP77838.1 - 0.023 15.2 0.4 0.023 15.2 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) S_locus_glycop PF00954.20 PRP77838.1 - 1.2 9.6 3.7 3.9 8.1 0.2 2.6 2 0 0 2 2 2 0 S-locus glycoprotein domain CAF-1_p150 PF11600.8 PRP77838.1 - 6.1 6.5 48.6 2.3 7.9 2.9 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase_Tyr PF07714.17 PRP77839.1 - 6.8e-80 268.1 0.1 9.5e-80 267.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77839.1 - 3.9e-58 196.9 0.0 5.6e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP77839.1 - 2.8e-39 132.7 76.8 5.4e-07 29.3 0.1 13.1 7 6 7 14 14 14 12 Leucine rich repeat LRR_4 PF12799.7 PRP77839.1 - 6.2e-30 102.7 92.8 0.00024 21.4 3.2 17.0 10 4 6 18 18 18 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP77839.1 - 2.8e-08 33.2 69.7 2.6 8.9 0.1 21.2 22 3 1 23 23 20 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP77839.1 - 5.2e-06 26.1 67.2 0.08 13.0 0.0 18.3 21 0 0 21 21 18 3 Leucine Rich repeat Kdo PF06293.14 PRP77839.1 - 0.00024 20.5 0.1 0.00043 19.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP77839.1 - 0.0021 17.4 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Syndecan PF01034.20 PRP77839.1 - 0.0031 17.4 0.4 0.0067 16.3 0.4 1.4 1 0 0 1 1 1 1 Syndecan domain FTA2 PF13095.6 PRP77839.1 - 0.0099 15.5 0.1 0.45 10.1 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 EphA2_TM PF14575.6 PRP77839.1 - 0.046 14.6 0.1 0.097 13.6 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AAA_3 PF07726.11 PRP77839.1 - 0.057 13.3 0.0 0.21 11.5 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF456 PF04306.13 PRP77839.1 - 0.087 13.1 0.2 0.25 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Pkinase_fungal PF17667.1 PRP77839.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LRRNT_2 PF08263.12 PRP77839.1 - 0.11 12.8 0.2 0.3 11.4 0.2 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_5 PF13306.6 PRP77839.1 - 2.2 8.2 6.5 20 5.2 0.0 4.5 4 1 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) LRR_2 PF07723.13 PRP77839.1 - 3.4 8.5 5.8 1.3e+02 3.5 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat Haspin_kinase PF12330.8 PRP77839.1 - 6.6 5.6 10.3 0.099 11.6 1.0 2.4 2 1 0 2 2 1 0 Haspin like kinase domain Topoisom_I_N PF02919.15 PRP77843.1 - 3.2e-87 291.5 3.4 3.2e-87 291.5 3.4 2.0 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 PRP77843.1 - 1.2e-33 116.3 0.7 1.2e-33 116.3 0.7 2.3 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core E1-E2_ATPase PF00122.20 PRP77844.1 - 3.8e-51 173.2 0.9 3.8e-51 173.2 0.9 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PRP77844.1 - 1.1e-32 113.2 5.0 1.1e-32 113.2 5.0 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PRP77844.1 - 3.7e-19 69.8 0.5 1.9e-18 67.5 0.5 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP77844.1 - 4.8e-17 61.8 0.0 1.2e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PRP77844.1 - 9.8e-14 50.8 0.3 2.3e-13 49.6 0.1 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PRP77844.1 - 0.00019 21.2 0.5 0.0005 19.9 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PRP77844.1 - 0.006 17.0 0.1 0.02 15.3 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_19 PF14559.6 PRP77845.1 - 1.9e-44 150.0 34.2 1.9e-07 31.5 0.7 16.3 14 3 3 17 17 15 9 Tetratricopeptide repeat LRR_8 PF13855.6 PRP77845.1 - 7.7e-30 102.5 33.4 3.9e-10 39.3 0.7 6.7 3 1 5 8 8 8 6 Leucine rich repeat TPR_14 PF13428.6 PRP77845.1 - 8.7e-29 97.8 19.8 0.073 13.9 0.1 18.3 15 4 5 20 20 17 5 Tetratricopeptide repeat TPR_2 PF07719.17 PRP77845.1 - 1.9e-25 86.9 53.0 0.0023 17.9 0.2 19.0 22 0 0 22 22 16 6 Tetratricopeptide repeat LRR_4 PF12799.7 PRP77845.1 - 1.4e-23 82.6 27.2 0.00011 22.5 0.3 7.9 6 2 1 7 7 6 6 Leucine Rich repeats (2 copies) TPR_8 PF13181.6 PRP77845.1 - 2.3e-21 74.2 32.6 0.0067 16.6 0.1 16.7 16 1 1 17 17 15 3 Tetratricopeptide repeat Ras PF00071.22 PRP77845.1 - 4.5e-21 75.1 0.0 2.6e-18 66.1 0.0 2.7 2 0 0 2 2 2 1 Ras family TPR_16 PF13432.6 PRP77845.1 - 5.5e-20 71.7 7.1 7.6e-05 23.3 0.1 12.8 14 1 1 15 15 11 2 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 PRP77845.1 - 3e-19 69.3 0.3 3.4e-18 65.9 0.1 2.8 2 1 0 2 2 1 1 Protein tyrosine kinase TPR_7 PF13176.6 PRP77845.1 - 7.6e-18 63.2 15.4 0.08 13.0 0.1 12.6 12 1 1 13 13 11 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP77845.1 - 2.1e-14 52.6 43.7 0.011 15.5 0.2 15.6 18 0 0 18 18 16 5 Tetratricopeptide repeat TPR_12 PF13424.6 PRP77845.1 - 2.9e-12 46.7 48.6 0.063 13.6 0.8 15.6 14 4 2 16 16 15 3 Tetratricopeptide repeat TPR_6 PF13174.6 PRP77845.1 - 5.3e-12 45.6 22.4 2.6 8.9 0.0 15.6 20 0 0 20 20 13 2 Tetratricopeptide repeat Pkinase PF00069.25 PRP77845.1 - 1.3e-11 44.4 0.0 1.4e-10 41.0 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP77845.1 - 1.4e-08 35.1 1.6 3.8e-08 33.7 1.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif ANAPC3 PF12895.7 PRP77845.1 - 5.8e-08 32.9 34.7 0.073 13.3 0.6 11.6 7 5 6 13 13 13 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 PRP77845.1 - 1.5e-06 28.1 11.2 0.037 14.1 0.0 6.8 8 0 0 8 8 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 PRP77845.1 - 2e-05 24.0 27.3 2.4 7.3 0.2 8.3 6 1 1 8 8 8 2 Tetratricopeptide repeat ChAPs PF09295.10 PRP77845.1 - 2.3e-05 23.6 0.1 2.3e-05 23.6 0.1 3.7 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 PRP77845.1 - 4.5e-05 23.5 10.4 0.081 13.1 0.1 6.5 6 1 1 7 7 6 2 Tetratricopeptide repeat LRR_1 PF00560.33 PRP77845.1 - 4.8e-05 23.3 28.2 0.98 10.2 0.0 10.4 9 2 0 9 9 7 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP77845.1 - 0.00024 20.9 22.3 0.55 10.4 0.6 6.3 5 0 0 5 5 5 3 Leucine Rich repeat TPR_11 PF13414.6 PRP77845.1 - 0.00027 20.6 21.2 3.9 7.3 0.1 10.2 10 1 1 11 11 9 1 TPR repeat TPR_17 PF13431.6 PRP77845.1 - 0.0015 18.8 12.5 1.7e+02 3.0 0.1 10.9 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_20 PF14561.6 PRP77845.1 - 0.0025 18.1 17.9 2.5 8.5 0.2 8.7 11 0 0 11 11 8 1 Tetratricopeptide repeat Kinase-like PF14531.6 PRP77845.1 - 0.0037 16.6 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TPR_10 PF13374.6 PRP77845.1 - 0.0047 16.8 21.0 3.8 7.5 0.0 10.1 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP77845.1 - 0.0051 16.2 25.9 4.2 6.6 0.2 8.0 6 3 1 8 8 8 1 MalT-like TPR region Roc PF08477.13 PRP77845.1 - 0.0091 16.2 0.0 0.24 11.6 0.0 2.6 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Alkyl_sulf_dimr PF14863.6 PRP77845.1 - 0.016 15.7 0.6 16 6.0 0.1 4.5 3 1 1 4 4 3 0 Alkyl sulfatase dimerisation SCAB_CC PF16712.5 PRP77845.1 - 0.097 12.5 0.1 0.37 10.6 0.0 2.0 2 0 0 2 2 1 0 Coiled-coil regions of plant-specific actin-binding protein TPR_4 PF07721.14 PRP77845.1 - 0.41 11.4 12.8 24 5.9 0.0 6.7 7 0 0 7 7 5 0 Tetratricopeptide repeat YfiO PF13525.6 PRP77845.1 - 1.6 8.4 6.9 3.4 7.3 0.1 4.2 3 1 1 4 4 4 0 Outer membrane lipoprotein SNAP PF14938.6 PRP77845.1 - 2.8 7.3 15.1 4.6 6.6 0.1 5.3 5 0 0 5 5 5 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 PRP77845.1 - 2.9 8.0 11.3 27 4.9 0.2 5.4 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain FAT PF02259.23 PRP77845.1 - 5.5 6.1 12.1 2.5 7.3 0.0 4.6 4 2 0 4 4 4 0 FAT domain Adeno_E3_CR2 PF02439.15 PRP77845.1 - 8.1 6.3 12.7 2.6 7.9 7.2 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Alba PF01918.21 PRP77846.1 - 5.2e-09 35.8 0.2 1.2e-08 34.7 0.1 1.6 2 0 0 2 2 2 1 Alba Rpp20 PF12328.8 PRP77846.1 - 0.023 14.6 0.1 0.026 14.5 0.1 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Pribosyltran PF00156.27 PRP77847.1 - 2.9e-26 91.9 0.0 3.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ribosomal_L26 PF16906.5 PRP77848.1 - 1e-29 102.8 3.3 1.4e-29 102.3 3.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 PRP77848.1 - 1.7e-06 27.8 3.2 4.9e-06 26.3 3.2 1.8 1 0 0 1 1 1 1 KOW motif tRNA-synt_2 PF00152.20 PRP77849.1 - 5.8e-77 258.9 0.1 1e-76 258.1 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PRP77849.1 - 8.5e-08 32.1 1.0 1.6e-07 31.2 1.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PRP77849.1 - 0.0071 15.8 0.2 0.2 11.1 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) CCDC-167 PF15188.6 PRP77849.1 - 0.095 13.1 5.3 0.3 11.5 5.3 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DNA_PPF PF02916.15 PRP77849.1 - 0.21 12.0 0.7 0.39 11.1 0.7 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor AUX_IAA PF02309.16 PRP77849.1 - 1.2 8.9 5.7 0.37 10.6 0.1 2.3 2 0 0 2 2 2 0 AUX/IAA family RNA_pol_Rpc4 PF05132.14 PRP77849.1 - 2 8.8 11.6 0.24 11.8 3.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 RasGEF PF00617.19 PRP77850.1 - 4.3e-53 180.1 0.5 1.6e-52 178.3 0.5 2.1 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP77850.1 - 6.5e-11 42.4 3.0 1.1e-10 41.6 0.1 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif CD36 PF01130.21 PRP77851.1 - 3.8e-101 338.9 3.5 4.8e-101 338.6 3.5 1.0 1 0 0 1 1 1 1 CD36 family Peptidase_M66 PF10462.9 PRP77851.1 - 0.0034 16.4 0.3 0.0057 15.6 0.3 1.3 1 0 0 1 1 1 1 Peptidase M66 PorA PF11271.8 PRP77851.1 - 0.01 15.1 0.0 0.61 9.3 0.0 2.3 2 0 0 2 2 2 0 Porin PorA Pkinase_Tyr PF07714.17 PRP77852.1 - 1.4e-34 119.5 0.0 5e-34 117.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77852.1 - 1e-33 116.9 0.1 3e-33 115.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Homeodomain PF00046.29 PRP77852.1 - 9.2e-30 102.3 9.9 8.5e-13 47.9 0.4 3.8 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 PRP77852.1 - 4.3e-06 26.5 5.2 0.05 13.5 0.1 4.1 4 0 0 4 4 4 2 Homeobox KN domain Homez PF11569.8 PRP77852.1 - 0.001 18.5 0.2 0.051 13.1 0.0 3.0 3 0 0 3 3 3 1 Homeodomain leucine-zipper encoding, Homez TFIIA PF03153.13 PRP77852.1 - 0.42 10.5 19.7 0.94 9.4 19.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBS PF00571.28 PRP77853.1 - 1.8e-20 73.1 1.0 0.00042 20.7 0.0 4.4 4 0 0 4 4 4 4 CBS domain DUF4787 PF16029.5 PRP77853.1 - 7.6e-06 25.9 5.3 1.4e-05 25.1 5.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) CoA_binding PF02629.19 PRP77853.1 - 0.13 13.0 0.1 0.28 11.9 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain DUF3099 PF11298.8 PRP77853.1 - 2.5 8.3 4.3 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) RWP-RK PF02042.15 PRP77854.1 - 2.4e-07 30.6 0.2 3.5e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 PRP77854.1 - 0.0001 22.0 0.1 0.00027 20.6 0.0 1.7 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 PRP77854.1 - 0.00054 19.7 0.0 0.0022 17.7 0.0 1.9 1 1 1 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 PRP77854.1 - 0.00097 19.2 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_psq PF05225.16 PRP77854.1 - 0.0028 17.4 0.1 0.0087 15.8 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_24 PF13412.6 PRP77854.1 - 0.029 13.9 0.1 0.075 12.6 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 PRP77854.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 MarR family HTH_28 PF13518.6 PRP77854.1 - 0.051 13.7 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 PRP77854.1 - 0.13 12.0 0.1 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 Abhydrolase_1 PF00561.20 PRP77855.1 - 5.9e-16 58.9 0.0 1.7e-14 54.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP77855.1 - 9.4e-09 36.2 0.0 1.5e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP77855.1 - 0.00078 18.8 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SDF PF00375.18 PRP77856.1 - 1.5e-107 360.0 28.7 1.7e-107 359.8 28.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family LapA_dom PF06305.11 PRP77856.1 - 0.69 9.8 3.7 0.55 10.1 0.5 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Glyco_transf_15 PF01793.16 PRP77857.1 - 1.7e-43 149.1 0.0 1.2e-42 146.4 0.0 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L11_N PF03946.14 PRP77860.1 - 6.2e-21 74.0 0.3 1e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 PRP77860.1 - 1.2e-15 57.8 0.3 2.1e-15 57.0 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain YicC_N PF03755.13 PRP77860.1 - 0.062 13.7 0.1 0.1 13.1 0.1 1.3 1 0 0 1 1 1 0 YicC-like family, N-terminal region GRAM PF02893.20 PRP77861.1 - 4.2e-08 33.1 0.1 1.1e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 GRAM domain DivIC PF04977.15 PRP77861.1 - 0.00041 20.1 24.1 0.014 15.2 7.2 4.7 3 1 1 4 4 4 2 Septum formation initiator SlyX PF04102.12 PRP77861.1 - 0.003 18.1 25.3 0.017 15.7 0.2 4.6 2 1 2 4 4 4 1 SlyX Phage_tail_NK PF16532.5 PRP77861.1 - 0.0097 15.6 0.1 0.43 10.2 0.1 2.5 2 0 0 2 2 2 1 Sf6-type phage tail needle knob or tip of some Caudovirales AAA_13 PF13166.6 PRP77861.1 - 0.12 11.0 25.7 0.64 8.6 23.5 2.0 1 1 0 1 1 1 0 AAA domain DUF1848 PF08902.11 PRP77861.1 - 0.25 11.1 4.5 0.21 11.3 2.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1848) ADIP PF11559.8 PRP77861.1 - 0.31 11.1 35.6 0.32 11.1 14.1 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 PRP77861.1 - 0.77 9.8 39.1 1.7 8.7 5.3 4.4 2 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding KASH_CCD PF14662.6 PRP77861.1 - 0.79 9.5 28.9 2 8.2 7.5 3.2 1 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 PRP77861.1 - 0.88 9.7 36.9 12 6.0 14.0 3.5 1 1 2 3 3 3 0 Tropomyosin like TSC22 PF01166.18 PRP77861.1 - 1.1 9.7 17.9 0.65 10.3 2.0 4.4 5 0 0 5 5 4 0 TSC-22/dip/bun family DUF5320 PF17253.2 PRP77861.1 - 1.8 9.7 15.2 21 6.3 4.7 3.8 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Med30 PF11315.8 PRP77861.1 - 2.4 8.3 19.2 3.4 7.9 16.3 2.4 1 1 1 2 2 2 0 Mediator complex subunit 30 APG6_N PF17675.1 PRP77861.1 - 2.4 8.7 33.7 22 5.6 20.5 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 PRP77861.1 - 3.4 6.2 21.9 2 7.0 1.0 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A TACC_C PF05010.14 PRP77861.1 - 3.5 7.4 29.9 5.6 6.7 24.1 2.8 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3584 PF12128.8 PRP77861.1 - 3.6 5.0 29.8 5.4 4.4 29.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Csm1_N PF18504.1 PRP77861.1 - 4.2 7.8 29.3 1.6 9.2 0.1 4.9 4 1 1 5 5 5 0 Csm1 N-terminal domain TPR_MLP1_2 PF07926.12 PRP77861.1 - 5.6 7.0 37.9 1.2 9.2 0.3 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein BST2 PF16716.5 PRP77861.1 - 9.2 6.9 30.2 0.23 12.1 0.5 4.7 4 1 1 5 5 5 0 Bone marrow stromal antigen 2 M PF02370.16 PRP77861.1 - 9.3 7.2 15.3 0.63 10.8 4.0 3.7 3 0 0 3 3 2 0 M protein repeat BRCT_2 PF16589.5 PRP77862.1 - 1.5e-07 31.7 0.0 6e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BUD22 PF09073.10 PRP77862.1 - 7.9e-05 22.2 34.9 0.00011 21.7 34.9 1.2 1 0 0 1 1 1 1 BUD22 BRCT PF00533.26 PRP77862.1 - 0.0014 19.0 1.9 0.0031 17.9 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PRP77862.1 - 0.002 18.1 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain RNA_polI_A34 PF08208.11 PRP77862.1 - 0.007 16.5 29.4 0.007 16.5 29.4 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF1682 PF07946.14 PRP77862.1 - 0.016 14.5 33.9 0.048 12.9 19.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) CDC45 PF02724.14 PRP77862.1 - 0.032 12.5 28.0 0.019 13.3 10.4 2.0 2 0 0 2 2 2 0 CDC45-like protein CDC27 PF09507.10 PRP77862.1 - 0.038 13.4 43.2 0.011 15.2 19.8 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF913 PF06025.12 PRP77862.1 - 0.05 12.6 19.0 0.081 11.9 7.3 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) TFIIF_alpha PF05793.12 PRP77862.1 - 0.064 11.8 50.9 0.024 13.2 26.8 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2052 PF09747.9 PRP77862.1 - 0.067 13.3 35.8 0.28 11.3 14.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 PRP77862.1 - 0.086 12.3 39.3 0.41 10.0 9.7 2.1 2 0 0 2 2 2 0 SDA1 DUF2457 PF10446.9 PRP77862.1 - 0.15 11.2 30.7 0.58 9.2 9.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RR_TM4-6 PF06459.12 PRP77862.1 - 0.16 11.8 40.3 0.044 13.6 21.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 PRP77862.1 - 0.17 11.3 32.1 0.14 11.5 12.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) SpoIIP PF07454.11 PRP77862.1 - 0.32 10.4 24.9 0.23 10.9 11.5 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) PPP4R2 PF09184.11 PRP77862.1 - 0.42 10.2 29.6 0.78 9.3 4.6 2.2 2 0 0 2 2 2 0 PPP4R2 AAA_23 PF13476.6 PRP77862.1 - 0.46 11.0 26.4 1.4 9.3 16.6 2.1 2 0 0 2 2 2 0 AAA domain DUF3391 PF11871.8 PRP77862.1 - 0.53 10.8 19.9 1.5 9.4 8.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Myc_N PF01056.18 PRP77862.1 - 0.69 9.8 21.4 0.24 11.3 4.7 2.2 2 0 0 2 2 2 0 Myc amino-terminal region DUF4834 PF16118.5 PRP77862.1 - 0.72 10.8 17.9 2.7 9.0 8.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) RNA_pol_Rpc4 PF05132.14 PRP77862.1 - 0.76 10.2 29.0 0.1 13.1 11.9 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 BORG_CEP PF14957.6 PRP77862.1 - 3.8 8.7 16.2 0.16 13.2 4.0 2.3 2 0 0 2 2 2 0 Cdc42 effector CobT PF06213.12 PRP77862.1 - 4.3 6.6 38.8 1.4 8.3 18.9 2.4 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT CSRNP_N PF16019.5 PRP77862.1 - 4.4 7.1 20.5 0.075 12.9 8.3 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF4045 PF13254.6 PRP77862.1 - 4.6 6.8 29.1 0.11 12.1 11.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Spt5_N PF11942.8 PRP77862.1 - 4.8 8.2 35.3 2.1 9.4 12.2 2.7 3 0 0 3 3 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3807 PF12720.7 PRP77862.1 - 4.8 7.4 33.6 0.08 13.2 13.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) TP53IP5 PF15331.6 PRP77862.1 - 6.4 6.9 26.9 0.044 13.9 11.0 2.1 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 DUF755 PF05501.11 PRP77862.1 - 6.6 7.0 28.9 10 6.4 16.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) TRAP_alpha PF03896.16 PRP77862.1 - 6.7 5.8 23.5 5.1 6.2 7.7 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit AAA_11 PF13086.6 PRP77862.1 - 7.4 6.3 21.8 3 7.6 11.2 2.1 2 0 0 2 2 2 0 AAA domain DUF4820 PF16091.5 PRP77862.1 - 8.3 5.7 22.7 0.81 9.0 9.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FYDLN_acid PF09538.10 PRP77862.1 - 9.6 6.9 29.8 3.7 8.3 14.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) NFACT-R_1 PF05670.13 PRP77863.1 - 3.5e-36 124.2 0.2 6.8e-36 123.2 0.0 1.6 2 0 0 2 2 2 1 NFACT protein RNA binding domain DUF1729 PF08354.10 PRP77863.1 - 0.044 12.7 0.2 0.045 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) tRNA_synt_1c_R2 PF04557.15 PRP77863.1 - 2 9.4 7.4 3.9 8.5 4.4 2.2 1 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 START PF01852.19 PRP77864.1 - 6.2e-07 29.0 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 START domain Myosin_head PF00063.21 PRP77865.1 - 1.2e-255 850.0 0.0 1.5e-255 849.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 PRP77865.1 - 4.5e-44 150.4 0.4 7.5e-44 149.7 0.4 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 PRP77865.1 - 1e-18 66.7 0.5 2e-18 65.7 0.5 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP77865.1 - 7.6e-17 60.9 0.2 2e-16 59.6 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP77865.1 - 1.8e-12 46.8 0.0 4.1e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 PRP77865.1 - 0.036 14.5 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 PRP77865.1 - 0.16 11.2 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.12 PRP77865.1 - 0.17 11.4 0.5 5 6.6 0.1 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Myb_DNA-binding PF00249.31 PRP77866.1 - 3.6e-22 78.3 4.4 1.7e-08 34.5 0.2 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP77866.1 - 6.8e-16 58.3 5.2 7.8e-14 51.7 0.2 3.5 3 1 1 4 4 4 3 Myb-like DNA-binding domain Homeodomain PF00046.29 PRP77867.1 - 8.2e-05 22.4 0.7 0.00026 20.8 0.7 1.9 1 0 0 1 1 1 1 Homeodomain RasGEF PF00617.19 PRP77868.1 - 9e-54 182.4 0.2 3e-53 180.6 0.2 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP77868.1 - 4e-08 33.4 0.1 1.4e-07 31.7 0.1 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif RhoGAP PF00620.27 PRP77868.1 - 6.7e-07 29.2 0.0 5.4e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain Mito_carr PF00153.27 PRP77869.1 - 1.5e-29 101.8 2.7 8.2e-17 60.9 0.1 4.4 3 2 1 4 4 4 4 Mitochondrial carrier protein Cofilin_ADF PF00241.20 PRP77870.1 - 2.7e-36 124.0 0.1 1.9e-24 85.8 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein ATP-synt_C PF00137.21 PRP77871.1 - 7.6e-36 122.3 37.4 1.3e-22 79.9 13.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Glycophorin_A PF01102.18 PRP77871.1 - 0.86 9.9 4.4 0.19 12.0 1.0 1.6 2 0 0 2 2 2 0 Glycophorin A Man-6-P_recep PF02157.15 PRP77871.1 - 2 7.4 4.4 16 4.5 0.1 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate receptor PIRT PF15099.6 PRP77871.1 - 3.8 7.1 6.0 1.1 8.8 2.3 1.8 1 1 0 2 2 2 0 Phosphoinositide-interacting protein family Peptidase_C97 PF05903.14 PRP77873.1 - 0.073 12.9 0.0 0.078 12.8 0.0 1.1 1 0 0 1 1 1 0 PPPDE putative peptidase domain CRIM PF16978.5 PRP77874.1 - 3.3e-07 30.5 0.0 7.8e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain RBD PF02196.15 PRP77874.1 - 2.7e-06 27.4 0.2 0.00051 20.1 0.1 2.6 2 0 0 2 2 2 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 PRP77874.1 - 0.016 15.4 1.1 0.086 13.1 0.1 2.3 2 0 0 2 2 2 0 TUG ubiquitin-like domain PI3K_rbd PF00794.18 PRP77874.1 - 0.039 14.1 0.1 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain SIN1_PH PF16979.5 PRP77874.1 - 0.08 13.2 2.2 0.17 12.1 0.2 2.4 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology HYLS1_C PF15311.6 PRP77874.1 - 0.18 12.5 1.1 0.71 10.7 0.3 2.4 2 1 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus AAA_lid_7 PF17867.1 PRP77875.1 - 0.0086 16.3 0.1 0.52 10.5 0.0 2.7 3 0 0 3 3 3 2 Midasin AAA lid domain Abhydrolase_2 PF02230.16 PRP77876.1 - 4.7e-50 170.4 0.0 5.6e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 PRP77876.1 - 1.2e-09 37.8 0.0 0.005 16.1 0.0 3.0 2 1 1 3 3 3 3 Serine aminopeptidase, S33 FSH1 PF03959.13 PRP77876.1 - 1.8e-08 34.3 0.0 1.1e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 PRP77876.1 - 1.5e-05 25.7 0.0 2.3e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP77876.1 - 0.00011 21.9 0.2 0.0019 17.9 0.2 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 PRP77876.1 - 0.003 17.1 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 PRP77876.1 - 0.0033 17.2 0.0 0.0087 15.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PRP77876.1 - 0.023 14.2 0.2 0.11 11.9 0.0 2.0 1 1 1 2 2 2 0 Prolyl oligopeptidase family Cutinase PF01083.22 PRP77876.1 - 0.032 14.2 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Peptidase_C50 PF03568.17 PRP77876.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C50 Esterase PF00756.20 PRP77876.1 - 0.17 11.5 0.1 0.31 10.6 0.1 1.7 1 1 0 1 1 1 0 Putative esterase Adap_comp_sub PF00928.21 PRP77877.1 - 5.9e-69 232.4 0.1 6.9e-69 232.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PRP77877.1 - 3e-05 24.0 0.1 6.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 PRP77877.1 - 0.0031 17.5 0.1 0.0069 16.4 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain LRR_8 PF13855.6 PRP77878.1 - 2.2e-36 123.4 33.6 4.3e-12 45.6 1.2 6.3 3 1 1 6 6 6 5 Leucine rich repeat RasGEF PF00617.19 PRP77878.1 - 3.1e-36 125.2 0.9 8.6e-36 123.8 0.9 1.8 1 0 0 1 1 1 1 RasGEF domain LRR_4 PF12799.7 PRP77878.1 - 2.4e-27 94.5 36.0 1.7e-05 25.0 0.7 8.7 8 0 0 8 8 8 6 Leucine Rich repeats (2 copies) Drf_GBD PF06371.13 PRP77878.1 - 9.4e-09 35.1 0.2 2.7e-08 33.6 0.2 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain RasGEF_N PF00618.20 PRP77878.1 - 5.7e-07 29.7 0.0 1.9e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Drf_FH3 PF06367.16 PRP77878.1 - 3.7e-06 26.7 0.4 1.3e-05 24.9 0.4 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain LRR_1 PF00560.33 PRP77878.1 - 6.7e-05 22.9 31.4 0.037 14.5 0.9 10.6 9 1 0 9 9 9 1 Leucine Rich Repeat LRR_9 PF14580.6 PRP77878.1 - 0.0004 19.9 12.9 0.11 12.0 0.4 4.6 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 PRP77878.1 - 0.00064 19.6 39.6 2 8.6 0.0 10.5 11 0 0 11 11 11 3 Leucine Rich repeat HPS3_N PF14761.6 PRP77878.1 - 0.02 14.4 0.3 0.05 13.1 0.3 1.6 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Vps53_N PF04100.12 PRP77879.1 - 1.3e-84 284.3 8.1 2.1e-84 283.7 8.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Fic PF02661.18 PRP77879.1 - 1.8e-25 89.6 0.0 1.3e-24 86.9 0.0 2.6 1 0 0 1 1 1 1 Fic/DOC family DUF2451 PF10474.9 PRP77879.1 - 0.0038 17.1 0.5 0.012 15.4 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Zw10 PF06248.13 PRP77879.1 - 0.014 14.0 3.6 0.029 13.0 3.6 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 HTH_5 PF01022.20 PRP77879.1 - 0.02 14.7 0.2 1.4 8.8 0.1 3.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Vps54_N PF10475.9 PRP77879.1 - 0.042 13.1 6.7 0.018 14.3 3.8 1.8 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF1664 PF07889.12 PRP77879.1 - 0.074 13.1 1.3 0.25 11.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 PRP77879.1 - 0.32 11.0 3.6 50 3.9 0.1 4.2 4 1 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_I PF06008.14 PRP77879.1 - 0.35 10.5 5.6 0.83 9.3 5.6 1.6 1 0 0 1 1 1 0 Laminin Domain I VPS53_C PF16854.5 PRP77879.1 - 1 9.2 0.0 1 9.2 0.0 2.7 3 0 0 3 3 3 0 Vacuolar protein sorting-associated protein 53 C-terminus DUF3486 PF11985.8 PRP77879.1 - 1.5 9.2 7.3 1.8 8.9 4.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3486) DUF2312 PF10073.9 PRP77880.1 - 0.013 15.1 5.0 0.013 15.1 5.0 1.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF4795 PF16043.5 PRP77880.1 - 0.037 13.6 7.7 0.042 13.4 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Goodbye PF17109.5 PRP77880.1 - 0.049 14.1 3.5 0.068 13.6 3.5 1.2 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain IFT46_B_C PF12317.8 PRP77880.1 - 0.073 12.8 3.9 0.083 12.6 3.9 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal HemX PF04375.14 PRP77880.1 - 0.091 12.0 9.2 0.1 11.9 9.2 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MCD_N PF17408.2 PRP77880.1 - 0.15 12.2 1.6 0.27 11.4 1.6 1.4 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain DUF4446 PF14584.6 PRP77880.1 - 0.18 11.8 4.1 0.22 11.5 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3492 PF11997.8 PRP77880.1 - 0.25 11.0 4.2 0.26 11.0 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) GEMIN8 PF15348.6 PRP77880.1 - 0.39 11.0 10.7 0.45 10.8 10.7 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Band_3_cyto PF07565.13 PRP77880.1 - 0.59 9.9 7.2 0.71 9.6 7.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NifQ PF04891.12 PRP77880.1 - 0.86 9.9 4.0 0.95 9.8 4.0 1.1 1 0 0 1 1 1 0 NifQ APG6_N PF17675.1 PRP77880.1 - 0.98 10.0 17.1 1.3 9.5 17.1 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 PRP77880.1 - 1.4 9.4 9.3 1.9 9.0 9.3 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.19 PRP77880.1 - 2 6.2 10.9 2.1 6.1 10.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2721 PF11026.8 PRP77880.1 - 5.6 6.9 4.7 6.5 6.6 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Presenilin PF01080.17 PRP77880.1 - 6.3 5.4 6.4 6.8 5.4 6.4 1.0 1 0 0 1 1 1 0 Presenilin Ribosomal_L15e PF00827.17 PRP77881.1 - 1.4e-89 298.9 10.3 1.5e-89 298.8 10.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Crystall PF00030.19 PRP77881.1 - 0.049 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin PPR_2 PF13041.6 PRP77882.1 - 2e-20 72.7 10.4 6.7e-08 32.6 0.0 6.2 3 3 4 7 7 7 4 PPR repeat family PPR_3 PF13812.6 PRP77882.1 - 2.1e-15 56.5 10.7 6.2e-06 26.2 0.3 5.1 2 2 3 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 PRP77882.1 - 1.9e-11 43.4 3.8 0.065 13.5 0.1 7.0 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 PRP77882.1 - 6.4e-11 42.0 1.4 0.00056 19.3 0.0 3.2 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP77882.1 - 1.9e-08 33.8 0.0 2 8.2 0.0 6.0 5 1 1 6 6 6 2 PPR repeat Exog_C PF18026.1 PRP77882.1 - 0.053 13.6 0.2 1.2 9.3 0.0 3.4 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain zf-RING_2 PF13639.6 PRP77883.1 - 4.2e-13 49.4 8.1 6.7e-13 48.7 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP77883.1 - 6.9e-10 38.6 8.4 1.1e-09 38.0 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP77883.1 - 6e-08 32.3 5.0 7.4e-08 32.0 2.9 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PRP77883.1 - 8.4e-08 32.4 11.5 2.5e-07 30.9 11.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PRP77883.1 - 2.8e-06 27.1 8.0 4.7e-06 26.4 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP77883.1 - 1.4e-05 24.8 4.7 2.3e-05 24.2 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP77883.1 - 4.1e-05 23.5 6.1 9.3e-05 22.4 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PRP77883.1 - 0.00024 21.1 0.6 0.00044 20.3 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 PRP77883.1 - 0.00044 20.1 7.1 0.0007 19.5 7.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 PRP77883.1 - 0.0084 15.9 3.2 0.016 15.0 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 PRP77883.1 - 0.0098 16.2 7.0 0.017 15.5 7.0 1.4 1 0 0 1 1 1 1 RING-like domain Prok-RING_4 PF14447.6 PRP77883.1 - 0.014 15.2 7.4 0.028 14.3 7.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PRP77883.1 - 0.041 14.0 6.2 0.068 13.3 6.2 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 PRP77883.1 - 0.081 12.6 6.2 0.14 11.8 6.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 PRP77883.1 - 0.62 10.2 7.1 1.4 9.1 7.1 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 PRP77883.1 - 1.6 8.9 8.9 8.5 6.6 8.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain Vps39_2 PF10367.9 PRP77883.1 - 1.7 9.1 7.2 4.3 7.8 0.1 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 PRP77883.1 - 1.8 8.7 7.6 3.2 7.9 7.6 1.5 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 PRP77883.1 - 4.8 7.4 6.0 21 5.4 6.3 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING RR_TM4-6 PF06459.12 PRP77883.1 - 8.6 6.1 8.2 15 5.3 8.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SH3_11 PF18103.1 PRP77884.1 - 0.58 10.4 3.5 0.24 11.6 0.5 1.9 2 0 0 2 2 2 0 Retroviral integrase C-terminal SH3 domain Keratin_assoc PF09775.9 PRP77887.1 - 5.1e-24 84.4 8.0 1.2e-23 83.1 8.0 1.6 1 1 0 1 1 1 1 Keratinocyte-associated protein 2 LRR_8 PF13855.6 PRP77889.1 - 2.4e-11 43.2 26.7 7.8e-05 22.4 1.2 5.1 4 1 1 5 5 5 4 Leucine rich repeat Pkinase PF00069.25 PRP77889.1 - 6.6e-09 35.5 0.1 3.1e-07 30.1 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77889.1 - 7.6e-09 35.2 0.0 1.3e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP77889.1 - 4.8e-07 30.0 29.4 0.0024 18.2 0.4 6.2 2 1 3 6 6 6 4 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP77889.1 - 0.044 13.1 0.0 0.095 12.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like LRR_4 PF12799.7 PRP77890.1 - 1e-07 32.2 1.5 0.0037 17.6 0.1 2.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP77890.1 - 6.3e-05 22.7 3.5 0.013 15.3 0.4 2.6 1 1 2 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 PRP77890.1 - 0.0028 17.9 4.1 0.66 10.8 0.1 4.0 3 1 0 3 3 3 1 Leucine Rich Repeat Bestrophin PF01062.21 PRP77891.1 - 1.4e-46 159.2 0.0 2.4e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ank_2 PF12796.7 PRP77891.1 - 9.2e-31 106.3 12.9 8.6e-11 42.3 0.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77891.1 - 1.7e-23 82.7 8.4 1.2e-05 25.8 0.0 6.4 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP77891.1 - 2.6e-18 65.8 8.3 3.5e-05 24.0 0.0 6.1 2 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77891.1 - 3.8e-16 57.6 11.7 0.0084 16.6 0.0 8.3 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 PRP77891.1 - 2.6e-10 40.3 19.0 0.024 15.1 0.0 7.9 8 1 1 9 9 9 3 Ankyrin repeat TraB PF01963.17 PRP77894.1 - 2.2e-10 40.9 0.3 1.5e-09 38.1 0.3 2.0 1 1 0 1 1 1 1 TraB family Homeodomain PF00046.29 PRP77895.1 - 4.9e-06 26.3 0.1 7.9e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain STN1_2 PF09170.10 PRP77896.1 - 0.057 13.6 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Glu_synthase PF01645.17 PRP77897.1 - 9.5e-154 512.0 0.1 1.8e-153 511.1 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 PRP77897.1 - 6e-91 304.8 0.0 3.7e-88 295.6 0.0 2.2 2 0 0 2 2 2 2 Glutamate synthase central domain GXGXG PF01493.19 PRP77897.1 - 1.7e-83 278.9 3.2 2.8e-83 278.2 3.2 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 PRP77897.1 - 3.6e-27 95.4 0.0 8.2e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 PRP77897.1 - 3e-21 75.3 0.5 6.8e-21 74.1 0.5 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 PRP77897.1 - 5.2e-09 36.2 0.0 2.2e-08 34.2 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PRP77897.1 - 6.3e-08 33.1 0.5 8.7e-05 23.0 0.0 3.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP77897.1 - 2e-06 27.3 0.3 0.2 10.9 0.0 3.7 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP77897.1 - 2.5e-06 27.3 0.3 0.00092 18.9 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PRP77897.1 - 6e-06 25.8 0.1 1.3e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 PRP77897.1 - 1.1e-05 25.0 0.0 4.3e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP77897.1 - 6.9e-05 21.7 0.2 0.00024 19.9 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PRP77897.1 - 0.00047 19.5 0.1 0.41 9.9 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PRP77897.1 - 0.00058 19.2 0.0 0.0028 16.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 PRP77897.1 - 0.00062 19.0 0.2 0.0022 17.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 PRP77897.1 - 0.00085 18.7 0.1 0.0022 17.3 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 PRP77897.1 - 0.011 16.2 0.0 1.5 9.3 0.0 3.0 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 PRP77897.1 - 0.011 14.2 0.0 1.7 7.0 0.0 3.0 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 PRP77897.1 - 0.015 14.4 0.1 0.1 11.6 0.3 2.2 3 0 0 3 3 3 0 FMN-dependent dehydrogenase NAD_binding_9 PF13454.6 PRP77897.1 - 0.025 14.5 0.1 0.33 10.9 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 PRP77897.1 - 0.072 12.2 0.7 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 PRP77897.1 - 0.085 12.2 0.0 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 PRP77897.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 PRP77897.1 - 0.15 12.1 0.0 27 4.8 0.0 2.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TBP PF00352.21 PRP77899.1 - 5.4e-62 205.8 0.4 5.1e-30 103.3 0.1 2.9 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 PRP77899.1 - 0.039 14.1 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) Glyco_transf_8C PF08437.10 PRP77899.1 - 0.077 13.1 0.2 0.37 10.9 0.2 2.3 1 0 0 1 1 1 0 Glycosyl transferase family 8 C-terminal HALZ PF02183.18 PRP77899.1 - 0.25 11.6 0.0 0.25 11.6 0.0 4.9 5 1 1 6 6 6 0 Homeobox associated leucine zipper ORC3_N PF07034.11 PRP77900.1 - 5.3e-23 81.7 9.0 2e-17 63.3 4.5 3.1 2 1 1 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 PRP77900.1 - 3.2e-14 53.2 1.2 2.2e-07 31.0 0.0 3.4 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal Pex2_Pex12 PF04757.14 PRP77900.1 - 0.02 14.5 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region IL2 PF00715.17 PRP77900.1 - 0.04 13.9 0.1 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 Interleukin 2 V-ATPase_G_2 PF16999.5 PRP77901.1 - 0.2 12.1 9.7 0.13 12.7 2.8 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit CRT10 PF08728.10 PRP77901.1 - 0.26 9.4 3.8 0.27 9.4 3.8 1.0 1 0 0 1 1 1 0 CRT10 Neur_chan_memb PF02932.16 PRP77901.1 - 9.1 6.3 7.4 13 5.8 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CBM9_2 PF16011.5 PRP77902.1 - 0.012 15.4 0.1 0.035 13.8 0.1 1.7 1 1 1 2 2 2 0 Carbohydrate-binding family 9 FAD_binding_4 PF01565.23 PRP77903.1 - 0.11 12.2 0.0 0.82 9.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain CPT_N PF16484.5 PRP77904.1 - 0.018 15.0 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus Pro-kuma_activ PF09286.11 PRP77906.1 - 4.2e-19 69.2 0.1 7e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Ank_3 PF13606.6 PRP77907.1 - 5.8e-06 26.3 0.0 0.057 14.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 PRP77907.1 - 0.00064 20.3 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77907.1 - 0.05 14.2 0.0 0.78 10.4 0.0 2.8 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Glu_syn_central PF04898.14 PRP77908.1 - 1.5e-50 172.3 0.1 1.9e-50 171.9 0.1 1.1 1 0 0 1 1 1 1 Glutamate synthase central domain SH3_1 PF00018.28 PRP77909.1 - 2.5e-20 71.8 0.9 6.3e-09 35.3 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 PRP77909.1 - 8.9e-20 70.1 0.2 2.5e-09 36.7 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 PRP77909.1 - 2.9e-17 62.2 6.4 1.4e-10 40.9 0.2 3.3 2 1 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 PRP77909.1 - 1.9e-05 24.9 3.9 2.3e-05 24.6 0.0 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SNARE PF05739.19 PRP77909.1 - 0.17 11.9 3.2 2.5 8.2 0.2 2.6 2 0 0 2 2 2 0 SNARE domain V_ATPase_I PF01496.19 PRP77909.1 - 0.39 8.6 8.7 0.52 8.2 8.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family p450 PF00067.22 PRP77910.1 - 6.4e-82 275.7 5.2 4.1e-81 273.1 5.2 1.9 1 1 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.7 PRP77910.1 - 1e-51 173.4 0.1 1.1e-09 38.8 0.1 8.7 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77910.1 - 1.1e-35 121.6 9.6 0.0012 19.4 0.0 13.2 7 4 9 16 16 16 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP77910.1 - 1.7e-28 98.3 10.5 0.05 13.9 0.0 15.6 7 4 9 17 17 17 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77910.1 - 4.3e-17 60.5 3.2 22 6.0 0.0 16.1 18 0 0 18 18 18 0 Ankyrin repeat Ank PF00023.30 PRP77910.1 - 1.6e-11 44.1 25.5 3.4 8.3 0.0 16.4 16 2 2 18 18 18 2 Ankyrin repeat Pfg27 PF09216.10 PRP77910.1 - 0.011 15.6 0.4 1.5 8.6 0.0 3.7 4 0 0 4 4 4 0 Pfg27 HDA2-3 PF11496.8 PRP77910.1 - 0.017 14.3 2.2 0.73 8.9 0.0 3.9 5 1 0 5 5 5 0 Class II histone deacetylase complex subunits 2 and 3 DUF3051 PF11252.8 PRP77910.1 - 0.032 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) RNase_H_2 PF13482.6 PRP77910.1 - 0.086 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 RNase_H superfamily HTH_13 PF11972.8 PRP77910.1 - 0.11 12.6 0.9 5.3 7.2 0.1 3.7 3 0 0 3 3 3 0 HTH DNA binding domain ADSL_C PF10397.9 PRP77910.1 - 0.94 10.1 3.1 2.1e+02 2.5 0.0 5.7 5 2 4 9 9 9 0 Adenylosuccinate lyase C-terminus PLDc PF00614.22 PRP77911.1 - 6.4e-20 70.5 0.2 5e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PRP77911.1 - 1.2e-15 57.6 0.1 1.9e-08 34.3 0.4 2.9 2 1 0 2 2 2 2 PLD-like domain FERM_M PF00373.18 PRP77912.1 - 6.3e-18 65.3 0.1 1.7e-17 63.9 0.1 1.8 1 1 0 1 1 1 1 FERM central domain Dynamitin PF04912.14 PRP77913.1 - 0.0045 16.4 0.7 0.0051 16.2 0.7 1.0 1 0 0 1 1 1 1 Dynamitin DUF2163 PF09931.9 PRP77913.1 - 0.12 12.6 0.1 0.12 12.5 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) SH2 PF00017.24 PRP77914.1 - 3.4e-10 39.9 0.0 5.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 PRP77914.1 - 0.18 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 SH2 domain Hist_deacetyl PF00850.19 PRP77915.1 - 1e-63 215.7 10.1 1.2e-63 215.4 0.1 3.6 3 1 0 3 3 3 1 Histone deacetylase domain Lebercilin PF15619.6 PRP77915.1 - 5.4e-07 29.5 20.2 5.4e-07 29.5 20.2 2.8 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Amidoligase_2 PF12224.8 PRP77915.1 - 0.0097 15.6 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 1 Putative amidoligase enzyme Fe_bilin_red PF05996.12 PRP77915.1 - 1.3 8.6 7.4 0.28 10.8 3.2 2.1 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase Cep57_CLD_2 PF14197.6 PRP77915.1 - 9.6 6.4 15.3 0.58 10.3 0.3 3.8 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Ras PF00071.22 PRP77916.1 - 3e-65 218.8 0.2 3.4e-65 218.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP77916.1 - 1.8e-35 121.7 0.0 2.7e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP77916.1 - 1.4e-14 53.9 0.1 1.7e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP77916.1 - 1e-07 31.7 0.3 2.4e-07 30.5 0.2 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP77916.1 - 2.4e-06 27.1 0.1 3.1e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP77916.1 - 0.00017 21.6 0.0 0.00039 20.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP77916.1 - 0.00019 21.4 0.3 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 PRP77916.1 - 0.0013 18.3 0.1 0.0015 18.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PRP77916.1 - 0.0055 15.9 2.9 0.22 10.6 0.8 2.8 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 PRP77916.1 - 0.013 15.3 0.1 0.032 14.0 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MCM PF00493.23 PRP77916.1 - 0.041 13.0 0.0 0.36 9.9 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 PRP77916.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP77916.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ubiquitin PF00240.23 PRP77917.1 - 1.7e-21 75.7 0.0 3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP77917.1 - 5.8e-11 42.1 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 PRP77917.1 - 9e-08 31.9 0.3 2.3e-07 30.6 0.3 1.8 1 0 0 1 1 1 1 UBA/TS-N domain STI1 PF17830.1 PRP77917.1 - 2.5e-06 27.3 43.5 0.021 14.8 1.6 5.0 2 2 3 5 5 5 4 STI1 domain Kelch_4 PF13418.6 PRP77917.1 - 0.00011 22.2 0.0 0.00032 20.7 0.0 1.8 1 0 0 1 1 1 1 Galactose oxidase, central domain Ubiquitin_2 PF14560.6 PRP77917.1 - 0.00047 20.6 0.0 0.0014 19.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Kelch_3 PF13415.6 PRP77917.1 - 0.00076 19.7 0.3 0.0038 17.5 0.0 2.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 PRP77917.1 - 0.0019 17.7 0.0 0.0044 16.6 0.0 1.6 1 0 0 1 1 1 1 Kelch motif TBK1_ULD PF18396.1 PRP77917.1 - 0.008 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP77917.1 - 0.015 15.6 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 PRP77917.1 - 0.018 15.6 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP77917.1 - 0.021 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 PRP77917.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair XPC-binding PF09280.11 PRP77917.1 - 0.1 12.3 43.2 0.34 10.7 1.0 5.5 2 2 3 5 5 5 0 XPC-binding domain Ubiquitin_4 PF18036.1 PRP77917.1 - 0.12 12.5 0.0 4.5 7.4 0.0 2.4 1 1 1 2 2 2 0 Ubiquitin-like domain HCNGP PF07818.13 PRP77917.1 - 1.1 10.0 4.3 4.1 8.1 0.1 3.4 3 1 0 3 3 3 0 HCNGP-like protein Pkinase_Tyr PF07714.17 PRP77918.1 - 5.6e-21 75.0 0.9 1.5e-20 73.6 0.9 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP77918.1 - 1.1e-17 63.8 32.5 7.5e-06 26.2 1.3 5.8 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP77918.1 - 1.2e-16 60.9 2.6 8.2e-16 58.2 2.6 2.0 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP77918.1 - 8.4e-15 54.3 32.1 2.3e-07 30.5 5.5 4.4 3 2 1 4 4 4 4 Leucine rich repeat GPS PF01825.21 PRP77918.1 - 3.7e-08 33.8 1.1 8.8e-08 32.6 1.1 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP77918.1 - 4.1e-07 29.7 26.9 4.3 8.3 3.1 8.5 7 0 0 7 7 7 3 Leucine Rich Repeat STATa_Ig PF18214.1 PRP77918.1 - 0.0062 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 STATa Immunoglobulin-like domain LRR_9 PF14580.6 PRP77918.1 - 0.15 11.6 7.7 0.87 9.1 0.3 3.1 1 1 2 3 3 3 0 Leucine-rich repeat DHHC PF01529.20 PRP77920.1 - 1.6e-34 118.9 14.1 1.6e-34 118.9 14.1 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 PRP77920.1 - 1.5e-25 89.5 4.4 7.8e-11 42.4 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP77920.1 - 5.8e-23 78.5 2.1 0.00013 22.1 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 PRP77920.1 - 5.5e-21 74.0 0.8 0.0002 21.7 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PRP77920.1 - 6.8e-20 71.2 5.8 1.3e-08 35.2 0.6 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP77920.1 - 1.2e-18 66.9 6.2 1.1e-09 38.3 0.2 5.0 2 2 3 5 5 5 3 Ankyrin repeats (many copies) DpnI PF06044.12 PRP77920.1 - 0.14 11.8 0.6 0.4 10.3 0.6 1.7 1 0 0 1 1 1 0 Dam-replacing family ANAPC15 PF15243.6 PRP77921.1 - 8.8e-06 26.0 4.6 1.5e-05 25.3 4.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 NYN PF01936.18 PRP77922.1 - 7.2e-07 29.8 0.0 1.2e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 NYN domain RabGAP-TBC PF00566.18 PRP77923.1 - 2.6e-49 167.8 0.3 4.7e-49 167.0 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 PRP77924.1 - 3.3e-31 106.9 0.2 9.2e-16 57.4 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP77924.1 - 5.7e-05 23.2 0.0 0.0033 17.5 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif ALMT PF11744.8 PRP77924.1 - 0.76 8.5 7.2 6.4 5.5 2.8 2.3 2 0 0 2 2 2 0 Aluminium activated malate transporter Eapp_C PF10238.9 PRP77924.1 - 0.8 9.8 10.5 2.5 8.1 4.3 2.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein PPL5 PF18168.1 PRP77924.1 - 3.9 6.7 11.3 0.29 10.4 4.6 2.3 2 0 0 2 2 2 0 Prim-pol family 5 Laminin_G_3 PF13385.6 PRP77925.1 - 1.8e-32 112.6 10.1 3.3e-16 59.8 2.0 2.8 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily RhoGEF PF00621.20 PRP77925.1 - 6.4e-23 81.9 0.1 1.4e-22 80.8 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PRP77925.1 - 7.9e-07 29.6 0.2 5.2e-06 26.9 0.2 2.5 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 PRP77925.1 - 9.8e-06 25.5 0.8 2.5e-05 24.2 0.8 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Toxin_R_bind_N PF07953.12 PRP77925.1 - 0.0028 17.4 3.1 0.36 10.5 0.9 2.6 2 0 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding Sialidase PF02973.16 PRP77925.1 - 0.003 17.1 0.2 1.5 8.3 0.0 3.3 3 1 0 3 3 3 1 Sialidase, N-terminal domain DUF4183 PF13799.6 PRP77925.1 - 0.012 15.4 0.0 6.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4183) Laminin_G_2 PF02210.24 PRP77925.1 - 0.061 13.9 0.1 11 6.7 0.0 2.8 3 0 0 3 3 3 0 Laminin G domain Pentaxin PF00354.17 PRP77925.1 - 0.066 12.9 0.5 1.2 8.8 0.1 2.7 2 0 0 2 2 2 0 Pentaxin family DUF4982 PF16355.5 PRP77925.1 - 0.081 12.9 0.0 0.78 9.7 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4982) Myb_DNA-binding PF00249.31 PRP77926.1 - 1.9e-05 24.8 2.0 3.6e-05 23.8 0.3 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP77926.1 - 0.00076 19.7 2.7 0.003 17.8 1.1 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF3677 PF12432.8 PRP77927.1 - 8.7e-05 22.8 3.4 0.00025 21.3 0.4 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3677) RasGEF PF00617.19 PRP77928.1 - 9e-42 143.3 2.2 1.3e-41 142.7 0.9 2.1 2 0 0 2 2 2 1 RasGEF domain PPR PF01535.20 PRP77928.1 - 1.6e-07 31.1 3.2 1.2e-06 28.4 0.3 3.8 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.6 PRP77928.1 - 1.1e-06 28.7 0.3 6e-06 26.4 0.3 2.4 1 0 0 1 1 1 1 PPR repeat family PPR_1 PF12854.7 PRP77928.1 - 3.2e-06 26.7 0.2 9e-06 25.3 0.2 1.9 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.6 PRP77928.1 - 0.008 16.2 0.8 0.13 12.3 0.3 3.1 3 0 0 3 3 3 1 Pentatricopeptide repeat domain RasGEF_N PF00618.20 PRP77928.1 - 0.016 15.5 0.1 0.1 12.8 0.1 2.4 2 0 0 2 2 2 0 RasGEF N-terminal motif zf-CSL PF05207.13 PRP77930.1 - 1.2e-22 79.4 1.8 1.9e-22 78.7 1.8 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 PRP77930.1 - 0.0021 18.2 0.3 0.012 15.7 0.1 2.1 2 0 0 2 2 2 1 C4-type zinc ribbon domain zf-RING_4 PF14570.6 PRP77930.1 - 0.013 15.2 0.4 0.023 14.5 0.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF365 PF04033.12 PRP77930.1 - 0.021 15.1 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Ldr_toxin PF13940.6 PRP77931.1 - 0.00064 19.7 5.8 0.0067 16.5 1.2 2.7 2 0 0 2 2 2 2 Toxin Ldr, type I toxin-antitoxin system Homeodomain PF00046.29 PRP77932.1 - 5.5e-17 61.4 1.6 1.6e-16 59.9 1.6 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP77932.1 - 2.6e-07 30.4 0.6 2.6e-07 30.4 0.6 1.8 2 0 0 2 2 2 1 Homeobox KN domain BrkDBD PF09607.10 PRP77932.1 - 0.0019 17.9 0.8 0.0027 17.5 0.1 1.6 2 0 0 2 2 2 1 Brinker DNA-binding domain HTH_23 PF13384.6 PRP77932.1 - 0.023 14.5 0.1 0.62 9.9 0.1 2.5 1 1 1 2 2 2 0 Homeodomain-like domain Pkinase PF00069.25 PRP77933.1 - 1.6e-37 129.3 0.0 2.1e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP77933.1 - 1e-16 61.0 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP77933.1 - 2.9e-05 24.1 0.1 4.4e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP77933.1 - 0.00032 20.1 0.1 0.00048 19.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP77933.1 - 0.023 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PRP77933.1 - 0.15 10.9 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PAN_4 PF14295.6 PRP77934.1 - 1.7e-06 27.8 2.8 1.7e-06 27.8 2.8 2.8 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PRP77934.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 PAN domain GalP_UDP_transf PF01087.22 PRP77936.1 - 7.6e-75 251.4 6.7 7.9e-71 238.3 0.1 3.1 3 1 0 3 3 3 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 PRP77936.1 - 3.6e-65 218.8 0.4 2.9e-54 183.3 0.0 2.6 3 0 0 3 3 3 2 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 PRP77936.1 - 0.00077 20.1 0.2 0.0029 18.3 0.2 2.0 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PRP77936.1 - 0.00083 19.8 1.9 0.0015 19.0 0.4 2.2 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DUF4931 PF16285.5 PRP77936.1 - 0.0097 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) CwfJ_C_1 PF04677.15 PRP77936.1 - 0.087 12.7 2.8 0.22 11.4 0.1 2.6 2 1 1 3 3 3 0 Protein similar to CwfJ C-terminus 1 DUF2203 PF09969.9 PRP77937.1 - 0.78 10.5 4.1 0.39 11.5 0.9 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Atg14 PF10186.9 PRP77937.1 - 2 7.4 7.8 2.9 6.9 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TENA_THI-4 PF03070.16 PRP77940.1 - 0.031 14.1 0.1 0.06 13.1 0.0 1.4 2 0 0 2 2 2 0 TENA/THI-4/PQQC family ACCA PF03255.14 PRP77940.1 - 0.22 11.4 1.4 0.37 10.6 1.4 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Oxysterol_BP PF01237.18 PRP77941.1 - 8.1e-49 166.4 6.0 3e-46 158.0 6.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein P33MONOX PF15302.6 PRP77941.1 - 0.013 15.2 0.8 0.021 14.5 0.8 1.3 1 0 0 1 1 1 0 P33 mono-oxygenase Fcf1 PF04900.12 PRP77942.1 - 3.2e-36 123.7 0.5 3.2e-36 123.7 0.5 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 PRP77942.1 - 7.8e-10 39.1 0.0 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 PIN like domain F-box-like PF12937.7 PRP77943.1 - 1e-09 38.1 0.0 2.1e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP77943.1 - 1.9e-08 34.0 0.0 4.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain Frankia_peptide PF14407.6 PRP77944.1 - 0.006 16.5 0.1 0.04 13.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Oxysterol_BP PF01237.18 PRP77945.1 - 1.7e-55 188.4 7.6 5.4e-52 176.9 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein PH PF00169.29 PRP77945.1 - 2.7e-09 37.5 0.4 9.2e-09 35.8 0.0 2.1 2 0 0 2 2 2 1 PH domain DUF1944 PF09175.10 PRP77945.1 - 0.089 12.6 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) PCI PF01399.27 PRP77946.1 - 1.1e-10 42.0 4.3 8.3e-09 35.9 0.1 2.9 3 0 0 3 3 3 2 PCI domain Ank_2 PF12796.7 PRP77947.1 - 1.5e-48 163.3 0.0 3.7e-09 37.1 0.0 5.5 2 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77947.1 - 4.2e-45 151.6 10.4 2.6e-05 24.7 0.0 10.3 3 1 10 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP77947.1 - 8.6e-30 102.4 4.7 0.007 16.7 0.0 12.3 3 2 10 13 13 13 8 Ankyrin repeats (many copies) Ank PF00023.30 PRP77947.1 - 4.2e-23 80.7 12.5 0.45 11.1 0.0 12.5 13 1 1 14 14 14 7 Ankyrin repeat Ank_3 PF13606.6 PRP77947.1 - 1.1e-21 74.5 2.1 0.81 10.5 0.0 12.7 14 0 0 14 14 14 3 Ankyrin repeat DUF3447 PF11929.8 PRP77947.1 - 0.00052 19.9 0.0 1.2 9.1 0.0 3.2 2 1 0 2 2 2 2 Domain of unknown function (DUF3447) DUF3734 PF12536.8 PRP77947.1 - 0.0033 17.7 5.0 21 5.5 0.0 5.8 2 1 6 8 8 8 0 Patatin phospholipase DUF4671 PF15710.5 PRP77947.1 - 0.1 11.4 1.6 0.42 9.4 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4671) SoxZ PF08770.11 PRP77947.1 - 0.14 11.9 0.1 3.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Sulphur oxidation protein SoxZ HTH_13 PF11972.8 PRP77947.1 - 0.14 12.2 0.0 2.8 8.1 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain F-box PF00646.33 PRP77947.1 - 0.23 11.4 1.2 0.54 10.2 1.2 1.6 1 0 0 1 1 1 0 F-box domain PIP5K PF01504.18 PRP77948.1 - 2.7e-74 249.8 0.0 4.5e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.29 PRP77948.1 - 5.9e-09 36.4 0.0 1.7e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 PH domain NAD_binding_10 PF13460.6 PRP77948.1 - 0.0075 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding RCDG1 PF15725.5 PRP77948.1 - 8.1 7.0 8.1 4 7.9 0.1 3.0 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Stm1_N PF09598.10 PRP77948.1 - 9.9 7.1 6.4 9.3 7.2 3.3 2.7 1 1 1 2 2 2 0 Stm1 TFIIF_beta PF02270.15 PRP77949.1 - 1.3e-21 76.5 1.3 2.5e-21 75.6 0.9 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 PRP77949.1 - 1.6e-07 32.1 1.3 4.4e-06 27.4 0.1 2.7 2 1 1 3 3 3 1 TFIIF, beta subunit N-terminus Med4 PF10018.9 PRP77950.1 - 2.2e-23 82.9 2.2 3e-23 82.5 2.2 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 HMMR_N PF15905.5 PRP77950.1 - 0.0031 17.0 6.9 0.0041 16.7 6.9 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF2482 PF10655.9 PRP77950.1 - 0.0048 17.4 0.9 0.0099 16.4 0.9 1.5 1 0 0 1 1 1 1 Hypothetical protein of unknown function (DUF2482) V_ATPase_I PF01496.19 PRP77950.1 - 0.044 11.7 3.4 0.047 11.6 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phage_lysis PF03245.13 PRP77950.1 - 0.053 13.6 3.0 0.087 12.9 3.0 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DUF3837 PF12939.7 PRP77950.1 - 0.22 12.0 4.6 0.19 12.2 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) PhoU PF01895.19 PRP77950.1 - 0.29 11.6 2.8 0.68 10.4 2.8 1.7 1 1 0 1 1 1 0 PhoU domain DASH_Dad3 PF08656.10 PRP77950.1 - 0.37 10.9 4.4 1 9.5 4.4 1.8 1 1 0 1 1 1 0 DASH complex subunit Dad3 Prominin PF05478.11 PRP77950.1 - 0.4 8.6 4.8 0.46 8.4 4.8 1.1 1 0 0 1 1 1 0 Prominin TMF_DNA_bd PF12329.8 PRP77950.1 - 0.66 10.0 18.1 0.62 10.1 7.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FeoB_Cyto PF17910.1 PRP77950.1 - 0.71 10.4 8.6 3.1 8.4 3.9 2.3 1 1 1 2 2 2 0 FeoB cytosolic helical domain z-alpha PF02295.17 PRP77950.1 - 0.82 9.8 4.0 0.35 11.0 0.4 2.3 2 1 1 3 3 3 0 Adenosine deaminase z-alpha domain FliT PF05400.13 PRP77950.1 - 2.3 9.1 7.0 2.3 9.1 0.4 2.3 1 1 1 2 2 2 0 Flagellar protein FliT Vps39_2 PF10367.9 PRP77951.1 - 4.3e-32 110.8 1.4 2.5e-31 108.3 1.1 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 PRP77951.1 - 6.7e-23 81.7 0.6 2.2e-22 79.9 0.0 2.2 2 1 1 3 3 3 1 CNH domain Clathrin PF00637.20 PRP77951.1 - 2.7e-06 27.3 2.2 0.013 15.4 0.2 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_1 PF10366.9 PRP77951.1 - 0.0053 17.0 0.5 0.034 14.4 0.0 2.7 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 PQQ_3 PF13570.6 PRP77951.1 - 0.087 13.3 0.0 0.48 11.0 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain DUF2175 PF09943.9 PRP77951.1 - 0.51 10.7 4.5 0.15 12.3 0.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) AAA_12 PF13087.6 PRP77952.1 - 2e-46 158.1 0.1 6e-46 156.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PRP77952.1 - 6e-28 98.3 4.6 1.2e-13 51.4 0.0 3.5 3 1 1 4 4 4 2 AAA domain Dna2 PF08696.11 PRP77952.1 - 6.8e-27 94.6 1.1 7.2e-23 81.5 0.0 3.0 2 1 1 3 3 3 2 DNA replication factor Dna2 AAA_30 PF13604.6 PRP77952.1 - 5.9e-11 42.4 0.0 1.4e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP77952.1 - 2.3e-07 31.2 0.0 1.2e-06 28.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PRP77952.1 - 0.00047 20.0 1.6 2.9 7.6 0.0 3.5 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 PRP77952.1 - 0.0035 17.2 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Helicase ResIII PF04851.15 PRP77952.1 - 0.0083 16.1 1.3 0.037 14.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 PRP77952.1 - 0.023 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 PRP77952.1 - 0.025 13.7 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.17 PRP77952.1 - 0.065 13.3 0.1 0.38 10.8 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain UvrD_C_2 PF13538.6 PRP77952.1 - 0.091 12.6 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Hist_deacetyl PF00850.19 PRP77953.1 - 5.9e-57 193.5 0.1 7.3e-57 193.2 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain CLU PF13236.6 PRP77954.1 - 2.4e-51 174.7 0.0 4.7e-51 173.7 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria C2 PF00168.30 PRP77954.1 - 2.1e-07 31.2 0.0 6.1e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 C2 domain eIF3_p135 PF12807.7 PRP77954.1 - 2.5e-05 24.4 0.2 0.00011 22.2 0.2 2.0 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Abhydro_lipase PF04083.16 PRP77955.1 - 3.8e-19 68.0 0.2 8.8e-19 66.8 0.2 1.6 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region ANAPC4_WD40 PF12894.7 PRP77957.1 - 7.1e-17 61.5 2.7 0.00032 21.0 0.0 4.8 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP77957.1 - 1.8e-14 53.9 16.2 0.0002 22.1 0.6 7.0 6 1 1 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 PRP77957.1 - 1.1e-06 28.7 2.6 0.00011 22.2 2.3 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 PRP77957.1 - 0.00022 20.4 0.6 0.14 11.2 0.0 3.0 2 1 1 3 3 3 2 Coatomer WD associated region IKI3 PF04762.12 PRP77957.1 - 0.018 13.0 7.8 1.1 7.2 0.0 3.1 2 1 1 3 3 3 0 IKI3 family Frtz PF11768.8 PRP77957.1 - 0.021 13.2 0.3 0.7 8.1 0.1 2.5 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DPPIV_N PF00930.21 PRP77957.1 - 0.03 13.1 2.0 2.4 6.8 0.9 3.4 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DNA_pol_B PF00136.21 PRP77959.1 - 5.9e-121 404.4 0.0 1.1e-120 403.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PRP77959.1 - 3.3e-40 138.2 0.0 5.9e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 PRP77959.1 - 3.1e-13 49.9 12.4 5.9e-13 49.0 10.7 2.2 1 1 1 2 2 2 1 DNA Polymerase alpha zinc finger RalF_SCD PF18248.1 PRP77959.1 - 0.096 12.6 0.9 15 5.6 0.0 2.5 2 0 0 2 2 2 0 RalF C-terminal Sec-7 capping domain NTF2 PF02136.20 PRP77961.1 - 2.6e-13 50.6 0.1 6.3e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 PRP77961.1 - 5.7e-07 29.6 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 F-box-like PF12937.7 PRP77962.1 - 2.6e-07 30.4 6.5 6.8e-07 29.1 4.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP77962.1 - 0.015 15.1 0.7 0.051 13.5 0.7 2.0 1 0 0 1 1 1 0 F-box domain Cyclin PF08613.11 PRP77963.1 - 7.1e-30 104.5 0.1 2.7e-29 102.6 0.2 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 PRP77963.1 - 4.6e-10 39.3 0.0 1.3e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain KIAA1430 PF13879.6 PRP77964.1 - 1.3e-17 64.4 8.3 1.3e-17 64.4 8.3 3.4 3 1 0 3 3 3 1 KIAA1430 homologue BPS1 PF05633.11 PRP77964.1 - 0.024 13.7 0.3 0.053 12.5 0.3 1.5 1 0 0 1 1 1 0 Protein BYPASS1-related ASXH PF13919.6 PRP77965.1 - 1.9e-05 24.7 4.0 4.7e-05 23.4 3.7 1.8 1 1 0 1 1 1 1 Asx homology domain RPN13_C PF16550.5 PRP77965.1 - 0.0039 17.3 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 UCH-binding domain Peptidase_C1 PF00112.23 PRP77966.1 - 1.9e-33 116.4 1.8 6.9e-33 114.6 1.8 1.9 1 0 0 1 1 1 1 Papain family cysteine protease WSC PF01822.19 PRP77966.1 - 4.7e-20 71.6 30.8 7.5e-12 45.3 13.1 3.3 2 0 0 2 2 2 2 WSC domain CAP PF00188.26 PRP77966.1 - 5.5e-13 49.9 0.3 3e-12 47.5 0.0 2.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Usp PF00582.26 PRP77967.1 - 3.4e-11 43.8 0.0 5.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family C2 PF00168.30 PRP77967.1 - 5.2e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain MqsR_toxin PF15723.5 PRP77967.1 - 0.11 12.9 0.5 0.52 10.7 0.1 2.1 2 0 0 2 2 2 0 Motility quorum-sensing regulator, toxin of MqsA RMP PF14996.6 PRP77968.1 - 3e-42 144.5 1.1 8.3e-42 143.0 1.1 1.8 1 0 0 1 1 1 1 Retinal Maintenance tRNA_bind_2 PF13725.6 PRP77969.1 - 0.075 12.7 0.4 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Possible tRNA binding domain ANAPC10 PF03256.16 PRP77970.1 - 7.9e-66 221.2 0.1 9.4e-66 221.0 0.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 PRP77970.1 - 0.0001 22.4 0.1 0.00014 22.0 0.1 1.3 1 0 0 1 1 1 1 F5/8 type C domain NT-C2 PF10358.9 PRP77972.1 - 2.9e-08 33.6 0.4 5.8e-08 32.6 0.4 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins PRAS PF15798.5 PRP77972.1 - 0.024 15.2 3.2 0.033 14.8 2.4 1.7 1 1 0 1 1 1 0 Proline-rich AKT1 substrate 1 ThiF PF00899.21 PRP77973.1 - 0.00016 21.2 0.2 0.00049 19.5 0.1 1.7 2 0 0 2 2 2 1 ThiF family zf-CCHC_3 PF13917.6 PRP77974.1 - 6.7e-14 51.6 8.0 1.2e-13 50.8 8.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 PRP77974.1 - 0.035 14.2 4.9 0.057 13.5 4.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Band_3_cyto PF07565.13 PRP77974.1 - 0.28 10.9 2.3 0.34 10.7 2.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Macoilin PF09726.9 PRP77974.1 - 0.53 8.8 14.8 0.6 8.6 14.8 1.0 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 PRP77974.1 - 0.88 9.1 45.0 0.78 9.3 42.9 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein ATP11 PF06644.11 PRP77974.1 - 1.4 8.6 4.6 1.8 8.3 4.6 1.3 1 0 0 1 1 1 0 ATP11 protein NPR3 PF03666.13 PRP77974.1 - 2.1 7.1 14.8 2.2 6.9 14.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SPX PF03105.19 PRP77974.1 - 2.6 7.9 26.1 2.8 7.7 26.1 1.1 1 0 0 1 1 1 0 SPX domain Pkinase_fungal PF17667.1 PRP77974.1 - 2.7 6.7 8.3 2.9 6.6 8.3 1.2 1 0 0 1 1 1 0 Fungal protein kinase PI3K_1B_p101 PF10486.9 PRP77974.1 - 3.2 5.4 12.8 3.6 5.2 12.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Presenilin PF01080.17 PRP77974.1 - 8 5.1 11.3 8.6 5.0 11.3 1.2 1 0 0 1 1 1 0 Presenilin CEP76-C2 PF15627.6 PRP77975.1 - 5.9e-30 103.9 0.0 1.1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain Ank_2 PF12796.7 PRP77975.1 - 0.0025 18.4 0.0 0.033 14.8 0.0 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Lung_7-TM_R PF06814.13 PRP77976.1 - 2.9e-11 43.2 3.5 2.9e-11 43.2 3.5 1.9 2 1 0 2 2 2 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 PRP77976.1 - 8.7e-08 31.9 3.6 8.7e-08 31.9 3.6 2.1 2 1 1 3 3 3 1 Rhodopsin-like GPCR transmembrane domain Lipase_GDSL_2 PF13472.6 PRP77977.1 - 3e-09 37.5 0.0 4.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PRP77977.1 - 2.3e-08 34.2 0.0 3.7e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Methyltransf_3 PF01596.17 PRP77979.1 - 8.2e-41 139.5 0.0 1.5e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Peptidase_M28 PF04389.17 PRP77979.1 - 8.6e-31 107.2 0.0 1.7e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Methyltransf_24 PF13578.6 PRP77979.1 - 5.8e-15 56.2 0.0 1.6e-14 54.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PRP77979.1 - 1.2e-08 35.0 0.5 9.7e-07 28.7 0.0 2.3 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_M20 PF01546.28 PRP77979.1 - 3.3e-08 33.5 0.1 8.2e-08 32.2 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 GCD14 PF08704.10 PRP77979.1 - 3.1e-06 27.1 0.0 8.3e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 PRP77979.1 - 9.7e-06 25.5 0.0 3e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 PRP77979.1 - 0.00046 19.8 0.0 0.0016 18.0 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltr_RsmB-F PF01189.17 PRP77979.1 - 0.00071 19.3 0.0 0.0084 15.8 0.0 2.5 3 0 0 3 3 3 1 16S rRNA methyltransferase RsmB/F Cons_hypoth95 PF03602.15 PRP77979.1 - 0.0024 17.6 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 PRP77979.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein CmcI PF04989.12 PRP77979.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Pyr_redox_2 PF07992.14 PRP77981.1 - 3.5e-67 226.7 8.1 5.5e-67 226.1 8.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PRP77981.1 - 9.1e-40 135.3 0.0 3.4e-39 133.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PRP77981.1 - 2.9e-23 82.2 6.8 2.1e-19 69.8 1.4 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Beta_helix PF13229.6 PRP77981.1 - 1.1e-11 44.8 44.0 1.6e-07 31.3 28.9 2.9 2 1 1 3 3 3 2 Right handed beta helix region FAD_oxidored PF12831.7 PRP77981.1 - 4.3e-09 36.2 0.5 4.3e-09 36.2 0.5 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PRP77981.1 - 5e-09 35.8 5.9 1.8e-06 27.4 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PRP77981.1 - 3e-08 33.1 2.7 3e-08 33.1 2.7 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 PRP77981.1 - 3.8e-07 29.6 0.1 0.0014 17.8 0.1 2.4 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NosD PF05048.13 PRP77981.1 - 8.4e-07 28.5 17.0 1.4e-06 27.8 4.2 2.7 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) FAD_binding_2 PF00890.24 PRP77981.1 - 1.1e-05 24.8 1.0 1.1e-05 24.8 1.0 2.9 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 PRP77981.1 - 2.1e-05 23.9 6.5 0.0048 16.2 1.6 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 PRP77981.1 - 0.00057 20.1 6.9 0.0042 17.3 0.8 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PRP77981.1 - 0.00082 18.7 1.9 0.0036 16.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 PRP77981.1 - 0.0031 16.3 0.8 0.0031 16.3 0.8 4.2 4 1 1 5 5 5 1 HI0933-like protein FAD_binding_3 PF01494.19 PRP77981.1 - 0.019 14.2 7.3 0.09 12.0 0.4 2.4 2 0 0 2 2 2 0 FAD binding domain XdhC_C PF13478.6 PRP77981.1 - 0.065 13.7 0.0 8.6 6.9 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 PRP77981.1 - 0.12 11.4 2.8 0.53 9.3 0.0 2.9 2 1 1 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.18 PRP77981.1 - 0.81 9.5 5.7 0.09 12.7 0.8 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 PRP77981.1 - 5.8 6.4 18.9 1.8 8.1 0.4 4.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase Pkinase_Tyr PF07714.17 PRP77982.1 - 2e-44 151.8 0.1 2.7e-43 148.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP77982.1 - 3.1e-40 138.2 0.0 8.2e-40 136.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain RA PF00788.23 PRP77982.1 - 6.3e-07 29.9 6.5 0.018 15.6 0.4 3.9 3 1 0 3 3 3 2 Ras association (RalGDS/AF-6) domain Haspin_kinase PF12330.8 PRP77982.1 - 0.00057 18.9 0.5 0.0034 16.4 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 PRP77982.1 - 0.0054 16.1 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP77982.1 - 0.0086 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family USP7_C2 PF14533.6 PRP77982.1 - 0.076 12.7 0.4 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal HIF-1 PF11413.8 PRP77983.1 - 0.067 12.6 0.4 0.12 11.8 0.4 1.5 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 NPR3 PF03666.13 PRP77984.1 - 5.8e-41 140.8 17.2 5.3e-23 81.6 2.0 3.4 2 1 2 4 4 4 3 Nitrogen Permease regulator of amino acid transport activity 3 Cytochrom_B561 PF03188.16 PRP77984.1 - 9.6e-10 38.7 8.8 2.2e-09 37.6 8.8 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 NPR2 PF06218.11 PRP77984.1 - 0.00023 20.1 0.0 0.0021 16.9 0.0 2.2 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Rootletin PF15035.6 PRP77984.1 - 0.034 14.2 0.2 0.06 13.4 0.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4079 PF13301.6 PRP77984.1 - 0.056 13.6 12.9 0.11 12.7 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) MFS_1 PF07690.16 PRP77986.1 - 2.3e-57 194.5 33.3 9.3e-49 166.2 4.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 PRP77986.1 - 3.9e-15 55.3 18.2 5.2e-09 35.1 3.5 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 PRP77986.1 - 1.3e-14 54.0 6.4 1.3e-14 54.0 6.4 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 PRP77986.1 - 0.0002 19.9 2.5 0.00044 18.8 2.5 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2207 PF09972.9 PRP77986.1 - 0.0051 15.6 0.1 0.0051 15.6 0.1 4.1 2 2 0 3 3 3 1 Predicted membrane protein (DUF2207) Tim54 PF11711.8 PRP77986.1 - 0.052 12.3 1.4 0.078 11.7 1.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GNAT_acetyltr_2 PF13718.6 PRP77986.1 - 0.22 10.9 1.2 0.43 9.9 1.2 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Ferlin_C PF16165.5 PRP77986.1 - 3.9 7.4 5.2 6.7 6.6 0.3 2.6 2 0 0 2 2 2 0 Ferlin C-terminus G0-G1_switch_2 PF15103.6 PRP77986.1 - 4 7.9 5.3 11 6.5 5.3 1.7 1 0 0 1 1 1 0 G0/G1 switch protein 2 Comm PF15957.5 PRP77987.1 - 0.064 13.6 1.2 0.21 12.0 1.2 1.7 1 1 1 2 2 2 0 Commissureless Sigma_reg_N PF13800.6 PRP77987.1 - 0.067 13.5 0.1 0.086 13.1 0.1 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TMEM52 PF14979.6 PRP77987.1 - 0.075 12.9 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 Voltage_CLC PF00654.20 PRP77988.1 - 1.3e-72 245.0 24.9 1.3e-72 245.0 24.9 1.5 1 1 0 1 1 1 1 Voltage gated chloride channel PRA1 PF03208.19 PRP77988.1 - 0.034 13.8 0.4 0.034 13.8 0.4 2.9 3 1 0 3 3 3 0 PRA1 family protein AlaE PF06610.13 PRP77988.1 - 0.043 13.8 0.4 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 L-alanine exporter AzlD PF05437.12 PRP77988.1 - 0.12 12.5 8.9 3.2 8.0 0.2 4.3 4 2 0 4 4 4 0 Branched-chain amino acid transport protein (AzlD) Actin PF00022.19 PRP77989.1 - 8.7e-14 50.9 0.0 1.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Actin WD40 PF00400.32 PRP77990.1 - 1.5e-13 50.9 15.1 0.0054 17.6 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP77990.1 - 1.9e-06 28.0 0.4 0.33 11.3 0.1 5.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP77990.1 - 0.00044 20.2 1.3 0.19 11.6 0.2 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ank_2 PF12796.7 PRP77991.1 - 4.2e-05 24.0 0.0 0.0001 22.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP77991.1 - 0.0079 16.8 0.0 0.35 11.5 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP77991.1 - 0.029 14.9 0.0 0.21 12.3 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 PRP77991.1 - 0.12 12.8 0.0 6 7.3 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) tRNA-synt_1 PF00133.22 PRP77992.1 - 4e-206 685.9 1.2 5e-205 682.3 0.1 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PRP77992.1 - 5e-39 133.7 0.0 1.5e-38 132.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PRP77992.1 - 2.2e-13 49.7 3.5 2e-05 23.5 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 PRP77992.1 - 2.2e-07 30.6 0.1 0.0027 17.3 0.0 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 PRP77992.1 - 0.0021 17.5 4.1 0.0081 15.5 0.0 3.3 4 0 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 PRP77992.1 - 0.14 11.4 1.8 0.34 10.2 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) ABC_tran_CTD PF16326.5 PRP77992.1 - 7.5 6.9 7.7 2.5 8.4 4.3 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain Vfa1 PF08432.10 PRP77993.1 - 2.3 8.5 21.1 2.8 8.2 21.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3043 PF11241.8 PRP77993.1 - 3.2 7.8 13.0 4.7 7.2 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Paramyxo_ncap PF00973.19 PRP77993.1 - 4.7 6.0 9.8 5.2 5.9 9.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SAPS PF04499.15 PRP77993.1 - 5.7 5.6 10.1 6 5.5 10.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hist_deacetyl PF00850.19 PRP77994.1 - 9e-79 265.1 0.4 1.2e-78 264.7 0.4 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF3784 PF12650.7 PRP77995.1 - 0.0057 16.8 2.8 0.36 11.0 0.1 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3784) Acetyltransf_7 PF13508.7 PRP77996.1 - 6e-06 26.6 0.1 1.4e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP77996.1 - 3.2e-05 23.8 0.0 6.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PRP77996.1 - 4.3e-05 23.6 0.0 0.0001 22.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP77996.1 - 0.0015 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP77996.1 - 0.019 15.2 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 PRP77996.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Amidinotransf PF02274.17 PRP77997.1 - 2.7e-108 362.1 1.7 8.5e-54 182.9 0.9 3.0 2 1 0 2 2 2 2 Amidinotransferase PAD_porph PF04371.15 PRP77997.1 - 0.0013 18.1 0.1 0.003 16.9 0.1 1.6 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase NCD3G PF07562.14 PRP77998.1 - 0.045 13.7 0.3 0.045 13.7 0.3 2.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Hepsin-SRCR PF09272.10 PRP77998.1 - 0.051 14.1 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Hepsin, SRCR domain TMEM52 PF14979.6 PRP77998.1 - 0.29 11.0 4.4 0.67 9.9 0.5 3.0 3 0 0 3 3 3 0 Transmembrane 52 TMEM154 PF15102.6 PRP77999.1 - 0.8 9.6 0.0 0.8 9.6 0.0 3.0 3 0 0 3 3 3 0 TMEM154 protein family F-box-like PF12937.7 PRP78000.1 - 7e-07 29.1 0.0 1.9e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP78000.1 - 0.00061 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain SMI1_KNR4 PF09346.10 PRP78000.1 - 0.0038 17.6 0.0 0.0075 16.7 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) F-box_4 PF15966.5 PRP78000.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box ubiquitin PF00240.23 PRP78001.1 - 8.4e-08 31.9 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 PRP78001.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 PRP78001.1 - 0.071 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PRP78001.1 - 0.13 12.9 0.0 0.27 11.8 0.0 1.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF1295 PF06966.12 PRP78002.1 - 2.3e-44 151.7 0.9 1.2e-42 146.0 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 PRP78002.1 - 0.00019 21.8 0.0 0.0011 19.3 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 PRP78002.1 - 0.0053 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 PRP78002.1 - 0.015 15.7 0.2 0.11 13.0 0.0 2.5 3 0 0 3 3 3 0 Phospholipid methyltransferase Syntaxin PF00804.25 PRP78003.1 - 5e-23 81.8 12.1 5e-23 81.8 12.1 2.5 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 PRP78003.1 - 1.2e-08 34.8 0.5 1.2e-08 34.8 0.5 1.9 2 0 0 2 2 2 1 SNARE domain DUF4655 PF15548.6 PRP78003.1 - 0.012 14.6 0.2 0.016 14.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) MCPsignal PF00015.21 PRP78003.1 - 0.031 14.1 5.9 0.23 11.2 1.9 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3040 PF11239.8 PRP78003.1 - 0.1 12.9 0.9 2.2 8.6 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) PCRF PF03462.18 PRP78003.1 - 2.2 8.1 11.6 0.65 9.8 2.7 2.9 1 1 2 3 3 3 0 PCRF domain Glyco_hydro_31 PF01055.26 PRP78004.1 - 3.8e-77 260.3 0.5 5.5e-77 259.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 MFS_1 PF07690.16 PRP78004.1 - 8.8e-40 136.7 43.7 8.8e-40 136.7 43.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gal_mutarotas_2 PF13802.6 PRP78004.1 - 9.2e-13 48.3 0.7 2.7e-12 46.8 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 PRP78004.1 - 4.9e-09 36.3 0.0 2.6e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Sugar_tr PF00083.24 PRP78004.1 - 2.8e-07 29.8 9.8 2.8e-07 29.8 9.8 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter WD40 PF00400.32 PRP78005.1 - 6.8e-11 42.5 0.1 0.014 16.2 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP78005.1 - 0.00011 22.4 0.0 0.00077 19.7 0.0 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP78005.1 - 0.00016 20.5 0.7 0.16 10.7 0.1 2.1 1 1 1 2 2 2 2 Nup133 N terminal like OLF PF02191.16 PRP78005.1 - 0.0013 18.4 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 2 Olfactomedin-like domain eIF2A PF08662.11 PRP78005.1 - 0.038 13.9 0.1 0.1 12.5 0.0 1.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A BBS2_N PF14781.6 PRP78005.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Frtz PF11768.8 PRP78005.1 - 0.12 10.7 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz WRKY PF03106.15 PRP78007.1 - 7e-27 93.4 14.1 3.7e-17 62.3 10.0 2.4 2 0 0 2 2 2 2 WRKY DNA -binding domain CPDase PF07823.11 PRP78008.1 - 4.9e-11 42.7 0.4 1.5e-07 31.3 0.0 2.6 2 1 0 2 2 2 2 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 PRP78008.1 - 0.00036 20.5 0.0 0.027 14.4 0.0 2.7 2 1 1 3 3 3 1 2'-5' RNA ligase superfamily DUF1581 PF07619.11 PRP78008.1 - 0.027 14.6 0.3 13 6.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) Type_III_YscX PF09474.10 PRP78008.1 - 0.1 12.9 0.0 25 5.2 0.0 2.7 1 1 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) MMM1 PF10296.9 PRP78009.1 - 4.8e-13 48.9 4.0 1.1e-06 28.0 0.0 2.6 2 1 1 3 3 3 2 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 PRP78009.1 - 1.6e-05 25.4 0.2 4.9e-05 23.8 0.2 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP78009.1 - 0.0022 18.4 1.7 0.02 15.3 1.7 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain FA_desaturase PF00487.24 PRP78009.1 - 0.27 11.0 2.3 0.15 11.8 0.3 1.6 2 0 0 2 2 2 0 Fatty acid desaturase RecG_N PF17190.4 PRP78009.1 - 9 7.1 8.7 0.29 11.9 0.2 2.8 3 0 0 3 3 3 0 RecG N-terminal helical domain Bac_rhamnosid6H PF17389.2 PRP78010.1 - 1.5e-18 67.2 0.4 2.6e-17 63.1 0.5 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 PRP78010.1 - 0.00029 19.8 0.0 0.00044 19.2 0.0 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_100 PF12899.7 PRP78010.1 - 0.0089 14.7 0.0 0.31 9.6 0.1 2.1 2 0 0 2 2 2 2 Alkaline and neutral invertase MORN PF02493.20 PRP78011.1 - 2.8e-14 52.0 21.4 4e-06 26.4 1.6 4.8 4 0 0 4 4 4 3 MORN repeat CTK3 PF12243.8 PRP78011.1 - 0.17 11.9 0.9 0.38 10.8 0.9 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 BAR_3 PF16746.5 PRP78011.1 - 1.3 8.7 6.5 2 8.0 6.5 1.2 1 0 0 1 1 1 0 BAR domain of APPL family Bac_rhamnosid6H PF17389.2 PRP78012.1 - 6e-19 68.5 0.7 1.1e-17 64.3 0.8 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 PRP78012.1 - 0.00016 20.6 0.0 0.00024 20.1 0.0 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_100 PF12899.7 PRP78012.1 - 0.022 13.4 0.0 0.61 8.7 0.1 2.1 2 0 0 2 2 2 0 Alkaline and neutral invertase Bac_rhamnosid_C PF17390.2 PRP78012.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain IFT57 PF10498.9 PRP78013.1 - 0.0071 15.4 12.6 0.011 14.8 12.6 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 ZapB PF06005.12 PRP78013.1 - 0.0075 16.7 6.4 0.023 15.1 6.4 1.8 1 0 0 1 1 1 1 Cell division protein ZapB TSC22 PF01166.18 PRP78013.1 - 0.058 13.7 2.1 0.14 12.5 0.9 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 PRP78013.1 - 0.067 13.8 6.2 0.17 12.5 6.2 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Wtap PF17098.5 PRP78013.1 - 0.11 12.4 6.5 0.2 11.5 6.5 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family KASH_CCD PF14662.6 PRP78013.1 - 0.28 11.0 16.9 0.054 13.3 12.5 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH MCU PF04678.13 PRP78013.1 - 0.28 11.3 4.0 0.21 11.7 1.8 1.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter TRAF_BIRC3_bd PF16673.5 PRP78013.1 - 0.33 10.8 3.9 0.76 9.6 3.9 1.6 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Spc7 PF08317.11 PRP78013.1 - 0.39 9.5 10.3 0.44 9.4 9.2 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 PRP78013.1 - 0.84 9.8 11.6 1.5 9.1 11.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) HAUS6_N PF14661.6 PRP78013.1 - 1.5 8.3 10.6 3.7 7.1 10.6 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FAM76 PF16046.5 PRP78013.1 - 1.9 7.8 9.6 3.5 6.9 9.6 1.3 1 0 0 1 1 1 0 FAM76 protein DUF3450 PF11932.8 PRP78013.1 - 3.6 6.8 14.0 1 8.6 10.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Dzip-like_N PF13815.6 PRP78013.1 - 6.9 6.7 11.5 4.4 7.3 8.9 2.0 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Gly_transf_sug PF04488.15 PRP78014.1 - 1.3e-15 57.8 0.3 2.6e-15 56.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 PRP78014.1 - 7.4 5.7 7.9 28 3.8 0.5 3.0 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain Pkinase_Tyr PF07714.17 PRP78016.1 - 4.1e-80 268.8 0.0 6.5e-80 268.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78016.1 - 8.4e-46 156.5 0.0 1.7e-45 155.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Guanylate_cyc PF00211.20 PRP78016.1 - 5.7e-31 107.5 1.4 1e-30 106.7 1.4 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 PRP78016.1 - 1.2e-27 95.5 87.3 1.1e-07 32.0 1.5 17.6 15 5 2 18 18 16 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP78016.1 - 1.1e-24 86.0 82.8 2.8e-09 36.6 7.7 14.4 7 5 8 15 15 15 10 Leucine rich repeat Kinase-like PF14531.6 PRP78016.1 - 6.6e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like dCache_1 PF02743.18 PRP78016.1 - 0.0004 20.3 5.1 0.0013 18.5 5.1 2.0 1 1 0 1 1 1 1 Cache domain LRR_1 PF00560.33 PRP78016.1 - 0.002 18.4 70.7 3.6 8.5 0.4 20.8 23 5 0 23 23 21 2 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP78016.1 - 0.0048 15.7 0.2 0.019 13.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase LRR_6 PF13516.6 PRP78016.1 - 0.025 14.6 60.8 3 8.1 0.0 17.2 21 0 0 21 21 19 0 Leucine Rich repeat SKG6 PF08693.10 PRP78016.1 - 0.37 10.2 6.9 0.92 9.0 6.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_9 PF14580.6 PRP78016.1 - 1.1 8.7 6.4 0.21 11.1 0.4 3.0 2 1 1 3 3 3 0 Leucine-rich repeat Syndecan PF01034.20 PRP78016.1 - 8.6 6.4 7.9 1.1 9.3 1.5 2.4 2 0 0 2 2 2 0 Syndecan domain Phage_holin_5_2 PF16079.5 PRP78018.1 - 0.2 12.0 1.1 0.67 10.3 1.1 1.9 1 1 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V Ceramidase PF05875.12 PRP78020.1 - 2.1e-53 181.5 25.7 2e-52 178.3 25.7 2.0 1 1 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 PRP78020.1 - 0.055 13.4 1.6 0.18 11.8 1.6 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide Sec62 PF03839.16 PRP78020.1 - 6.6 6.2 16.6 0.76 9.2 0.1 2.4 2 0 0 2 2 2 0 Translocation protein Sec62 Utp13 PF08625.11 PRP78021.1 - 5e-28 97.8 1.1 9.8e-28 96.8 1.1 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain BUD22 PF09073.10 PRP78021.1 - 0.015 14.7 22.4 0.016 14.6 22.4 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 PRP78021.1 - 0.032 12.7 21.1 0.033 12.7 21.1 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF2201_N PF13203.6 PRP78021.1 - 0.17 11.4 2.2 0.18 11.3 2.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain SAPS PF04499.15 PRP78021.1 - 1.2 7.8 6.7 1.3 7.7 6.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PhoU PF01895.19 PRP78021.1 - 1.4 9.5 8.7 0.68 10.4 6.0 1.9 2 1 0 2 2 2 0 PhoU domain V_ATPase_I PF01496.19 PRP78021.1 - 4.7 5.0 5.0 5.5 4.8 5.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RP-C_C PF11800.8 PRP78021.1 - 5.1 7.1 6.6 8 6.5 6.6 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_S41 PF03572.18 PRP78022.1 - 1.9e-11 43.8 0.0 4.7e-07 29.5 0.0 2.9 2 0 0 2 2 2 2 Peptidase family S41 RIFIN PF02009.16 PRP78022.1 - 0.00049 20.1 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Rifin DAP10 PF07213.11 PRP78022.1 - 0.0047 16.9 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 DAP10 membrane protein TMEM154 PF15102.6 PRP78022.1 - 0.011 15.7 0.2 0.029 14.3 0.2 1.7 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 PRP78022.1 - 0.047 13.5 0.3 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Glycophorin_A PF01102.18 PRP78022.1 - 0.066 13.4 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 Glycophorin A Podoplanin PF05808.11 PRP78022.1 - 0.13 12.3 14.1 0.016 15.3 6.5 2.4 1 1 1 2 2 2 0 Podoplanin BPTA PF17044.5 PRP78022.1 - 0.26 11.1 1.3 6 6.7 0.1 2.6 2 0 0 2 2 2 0 Borrelial persistence in ticks protein A Syndecan PF01034.20 PRP78022.1 - 0.35 10.8 2.0 0.45 10.5 0.6 1.9 2 0 0 2 2 2 0 Syndecan domain Sugar_tr PF00083.24 PRP78023.1 - 3.9e-34 118.3 24.1 3.1e-32 112.0 24.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP78023.1 - 6.1e-29 101.0 35.2 6.1e-29 101.0 35.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 PRP78026.1 - 2.7e-60 204.0 0.0 4.8e-44 150.7 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78026.1 - 2.8e-40 138.2 0.0 9.1e-29 100.5 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP78026.1 - 1.5e-06 27.8 0.0 4.9e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PRP78026.1 - 1.5e-05 24.0 1.2 2.1e-05 23.5 0.0 1.8 2 1 0 2 2 2 1 Fungal protein kinase HSD3 PF15244.6 PRP78026.1 - 0.083 12.4 8.6 0.13 11.8 8.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Sec63 PF02889.16 PRP78027.1 - 4.4e-164 543.8 4.2 3.5e-91 304.9 0.4 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 PRP78027.1 - 6.2e-46 156.4 0.0 3.3e-26 92.1 0.1 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 PRP78027.1 - 6.1e-33 113.3 0.9 1.7e-32 111.9 0.3 2.2 2 0 0 2 2 1 1 N-terminal helicase PWI domain ResIII PF04851.15 PRP78027.1 - 3.1e-27 95.6 0.0 2e-14 53.9 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP78027.1 - 5.2e-13 49.3 0.0 6.5e-07 29.7 0.0 3.9 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 PRP78027.1 - 1.4e-05 25.4 0.0 0.15 12.4 0.1 3.4 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 PRP78027.1 - 0.00012 21.3 0.0 0.069 12.2 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 PRP78027.1 - 0.00019 21.0 0.0 0.039 13.4 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein SWI2_SNF2 PF18766.1 PRP78027.1 - 0.0015 18.2 0.0 0.13 11.9 0.0 2.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_11 PF13086.6 PRP78027.1 - 0.0093 15.8 0.7 2.4 7.9 0.0 3.4 3 1 1 4 4 4 1 AAA domain AAA_7 PF12775.7 PRP78027.1 - 0.015 14.8 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 PRP78027.1 - 0.034 13.9 0.1 20 4.9 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PRP78027.1 - 0.05 13.0 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ThiF PF00899.21 PRP78028.1 - 2.1e-44 151.7 0.0 6.5e-34 117.4 0.0 2.1 1 1 1 2 2 2 2 ThiF family E2_bind PF08825.10 PRP78028.1 - 8e-22 77.2 0.1 1.7e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 PRP78028.1 - 0.0038 17.3 0.1 0.081 13.0 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.9 PRP78028.1 - 0.0098 15.8 1.6 0.24 11.3 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Ecm33 PF12454.8 PRP78028.1 - 0.017 15.3 0.8 0.032 14.4 0.8 1.4 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Xin PF08043.12 PRP78028.1 - 0.12 12.1 0.2 0.31 10.7 0.2 1.7 1 0 0 1 1 1 0 Xin repeat Scramblase PF03803.15 PRP78029.1 - 3.1e-52 177.0 0.0 4.1e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Scramblase Peptidase_C28 PF05408.11 PRP78029.1 - 0.18 11.6 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase IQ PF00612.27 PRP78030.1 - 1.4e-15 55.5 14.1 9.3e-06 25.0 0.1 4.3 4 0 0 4 4 4 3 IQ calmodulin-binding motif Ribosomal_S9 PF00380.19 PRP78031.1 - 1.1e-49 167.9 0.4 1.7e-26 93.1 0.0 2.4 1 1 1 2 2 2 2 Ribosomal protein S9/S16 GPW_gp25 PF04965.14 PRP78031.1 - 0.12 12.2 0.1 7.2 6.5 0.1 2.4 1 1 0 1 1 1 0 Gene 25-like lysozyme MAT1 PF06391.13 PRP78032.1 - 1.8e-22 80.2 24.9 1.8e-22 80.2 24.9 1.7 1 1 1 2 2 2 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 PRP78032.1 - 0.0057 16.5 2.0 0.013 15.3 2.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LMBR1 PF04791.16 PRP78032.1 - 4.2 6.2 8.7 4.8 6.0 8.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HALZ PF02183.18 PRP78033.1 - 0.0091 16.2 1.0 0.021 15.0 1.0 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper DivIC PF04977.15 PRP78033.1 - 0.035 13.9 0.4 0.035 13.9 0.4 2.9 3 0 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 PRP78033.1 - 0.035 14.2 0.8 0.035 14.2 0.8 2.1 2 0 0 2 2 2 0 bZIP transcription factor NICE-3 PF07406.11 PRP78033.1 - 0.079 12.9 2.7 0.1 12.6 0.5 2.0 2 0 0 2 2 2 0 NICE-3 protein EccE PF11203.8 PRP78033.1 - 0.12 12.7 0.8 0.38 11.1 0.8 1.9 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE WD40_alt PF14077.6 PRP78033.1 - 0.18 11.7 2.2 0.56 10.1 2.2 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif MIT PF04212.18 PRP78034.1 - 1e-23 83.2 10.2 7.3e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Arrestin_C PF02752.22 PRP78034.1 - 3.8e-09 37.1 0.1 8.8e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain LIM PF00412.22 PRP78034.1 - 0.0096 16.1 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 LIM domain ADSL_C PF10397.9 PRP78034.1 - 0.019 15.5 0.2 0.036 14.6 0.2 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus TPR_1 PF00515.28 PRP78034.1 - 0.11 12.4 7.4 0.32 10.9 0.5 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat USP8_dimer PF08969.11 PRP78034.1 - 0.27 11.4 5.5 1 9.6 0.6 2.8 3 0 0 3 3 3 0 USP8 dimerisation domain TPR_2 PF07719.17 PRP78034.1 - 1 9.6 10.0 3.3 8.1 0.6 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat GPS PF01825.21 PRP78035.1 - 4.2e-11 43.2 7.4 4.2e-11 43.2 7.4 3.9 4 0 0 4 4 4 1 GPCR proteolysis site, GPS, motif TIG PF01833.24 PRP78035.1 - 5.6e-07 29.5 5.5 5.6e-07 29.5 5.5 4.9 5 0 0 5 5 5 2 IPT/TIG domain Hemopexin PF00045.19 PRP78035.1 - 0.0002 21.2 0.0 0.89 9.6 0.0 2.6 2 0 0 2 2 2 2 Hemopexin LRR_8 PF13855.6 PRP78035.1 - 0.00071 19.3 0.2 9.6 6.1 0.0 4.8 4 1 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 PRP78035.1 - 0.0027 18.1 3.3 3.3 8.3 0.1 5.6 7 0 0 7 7 7 1 Leucine Rich repeats (2 copies) DUF948 PF06103.11 PRP78035.1 - 0.0053 17.0 1.5 0.018 15.3 0.3 2.3 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) LRRNT_2 PF08263.12 PRP78035.1 - 0.013 15.8 3.1 0.044 14.1 3.1 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Ferritin-like PF12902.7 PRP78037.1 - 3.8e-18 66.2 0.0 7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like S_4TM PF18159.1 PRP78038.1 - 0.038 13.3 0.3 0.038 13.3 0.3 2.2 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DUF2070 PF09843.9 PRP78038.1 - 5.6 5.1 12.0 12 4.0 12.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase PF00069.25 PRP78039.1 - 2.5e-42 145.1 0.0 4.2e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78039.1 - 2.7e-33 115.3 0.0 3.7e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP78039.1 - 5.3e-06 26.0 0.0 7.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP78039.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP78039.1 - 0.0098 14.7 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase mRNA_cap_enzyme PF01331.19 PRP78040.1 - 3.7e-26 92.2 0.1 2.1e-19 70.2 0.0 2.5 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 PRP78040.1 - 1e-13 51.9 3.6 5.4e-13 49.5 0.8 2.7 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain mRNA_triPase PF02940.15 PRP78040.1 - 5.3e-09 36.1 1.8 2.7e-07 30.6 1.1 2.4 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain DNA_ligase_A_M PF01068.21 PRP78040.1 - 0.0015 18.2 0.5 0.085 12.5 0.0 3.1 2 1 1 3 3 3 1 ATP dependent DNA ligase domain Pox_ATPase-GT PF10640.9 PRP78040.1 - 0.029 13.3 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase SH3_9 PF14604.6 PRP78042.1 - 3.6e-14 52.3 1.7 6.3e-08 32.4 0.1 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 PRP78042.1 - 6.5e-13 48.1 0.7 7e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 PRP78042.1 - 7.1e-11 41.6 0.1 6.7e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain TSC22 PF01166.18 PRP78042.1 - 0.82 10.0 3.4 4.2 7.8 0.3 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family Nup54 PF13874.6 PRP78042.1 - 1.9 8.6 5.2 5.3 7.1 0.2 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 SGL PF08450.12 PRP78043.1 - 1.9e-77 260.2 0.0 3.4e-77 259.3 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region GPS PF01825.21 PRP78043.1 - 1.8e-10 41.2 6.2 1.8e-10 41.2 6.2 2.5 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP78043.1 - 7.1e-09 35.3 0.1 4.1e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78043.1 - 5.8e-08 32.4 0.0 1.7e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP78043.1 - 0.00058 19.6 0.1 2.6 7.9 0.1 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRRNT_2 PF08263.12 PRP78043.1 - 0.0037 17.5 0.9 0.011 16.0 0.9 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 PRP78043.1 - 0.0044 17.4 0.4 14 6.3 0.0 4.0 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) Mucin PF01456.17 PRP78043.1 - 1.6 8.7 37.0 0.054 13.5 30.7 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein GPS PF01825.21 PRP78045.1 - 2.4e-10 40.8 7.4 2.4e-10 40.8 7.4 3.1 4 0 0 4 4 4 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP78045.1 - 4.9e-07 29.3 1.0 1.4e-05 24.6 1.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP78045.1 - 2.2e-06 27.3 2.7 11 5.8 0.0 7.0 6 2 1 8 8 8 1 Leucine rich repeat LRR_4 PF12799.7 PRP78045.1 - 1.2e-05 25.6 6.6 42 4.7 0.0 7.7 7 2 0 9 9 9 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP78045.1 - 4.8e-05 22.9 0.8 0.00039 19.9 0.8 2.0 1 1 0 1 1 1 1 Protein kinase domain LRRNT_2 PF08263.12 PRP78045.1 - 0.15 12.4 8.8 0.048 14.0 2.7 2.9 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain BACK PF07707.15 PRP78046.1 - 4.7e-05 23.4 0.0 0.00014 21.9 0.0 1.8 1 1 0 1 1 1 1 BTB And C-terminal Kelch zf-MIZ PF02891.20 PRP78047.1 - 0.089 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger NUDIX PF00293.28 PRP78048.1 - 1.5e-20 73.5 0.1 2.7e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain PAN_4 PF14295.6 PRP78048.1 - 2.1e-05 24.3 7.0 2.1e-05 24.3 7.0 3.2 2 1 0 2 2 2 1 PAN domain Chitin_bind_1 PF00187.19 PRP78048.1 - 2.8e-05 24.5 21.5 2.8e-05 24.5 21.5 3.0 3 0 0 3 3 3 1 Chitin recognition protein PAN_2 PF08276.11 PRP78048.1 - 0.0067 16.5 5.1 0.032 14.4 5.1 2.1 1 0 0 1 1 1 1 PAN-like domain GPS PF01825.21 PRP78050.1 - 1.3e-19 70.4 28.7 2.4e-10 40.7 6.2 3.9 4 0 0 4 4 4 2 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP78050.1 - 8.1e-16 58.1 0.9 3e-07 30.0 0.0 3.9 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP78050.1 - 1.9e-14 53.7 0.1 3.7e-07 29.8 0.0 3.1 2 2 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 PRP78050.1 - 1.3e-06 28.0 7.4 0.078 12.8 0.1 6.4 6 1 2 8 8 8 3 Leucine rich repeat EphA2_TM PF14575.6 PRP78050.1 - 0.00022 22.0 0.2 0.89 10.5 0.0 2.6 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain LRR_4 PF12799.7 PRP78050.1 - 0.00029 21.2 10.1 12 6.5 0.0 6.7 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PRP78050.1 - 0.014 15.7 0.9 0.014 15.7 0.9 3.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain MAP17 PF15807.5 PRP78050.1 - 0.047 13.9 1.0 0.79 10.0 0.1 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LRR_1 PF00560.33 PRP78050.1 - 0.66 10.7 3.0 1.4e+02 3.6 0.1 5.2 4 0 0 4 4 4 0 Leucine Rich Repeat GPS PF01825.21 PRP78051.1 - 4.5e-11 43.1 5.8 1.1e-10 41.8 5.8 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP78051.1 - 1.9e-10 40.6 0.0 1.3e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78051.1 - 1.2e-08 34.5 0.1 2.9e-07 30.1 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase BatA PF07584.11 PRP78051.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Pkinase_Tyr PF07714.17 PRP78052.1 - 1.8e-62 210.9 0.0 3.3e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP78052.1 - 1.4e-43 146.1 119.9 0.00013 22.2 0.3 18.4 8 5 10 21 21 21 18 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP78052.1 - 1e-42 146.3 0.0 2.1e-42 145.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP78052.1 - 1.1e-42 143.7 118.5 1.9e-07 30.7 4.8 16.2 8 4 8 17 17 17 16 Leucine rich repeat LRR_9 PF14580.6 PRP78052.1 - 1.2e-09 38.0 30.1 0.00045 19.8 0.3 8.1 3 2 4 8 8 8 4 Leucine-rich repeat Kdo PF06293.14 PRP78052.1 - 0.00034 20.0 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP78052.1 - 0.017 14.1 0.2 0.082 11.8 0.2 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Amnionless PF14828.6 PRP78052.1 - 0.061 12.2 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Amnionless Pkinase_fungal PF17667.1 PRP78052.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Adeno_E3_CR2 PF02439.15 PRP78052.1 - 0.88 9.4 5.6 2.9 7.7 5.6 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_4 PF12799.7 PRP78053.1 - 6.4e-07 29.6 1.9 0.0042 17.5 0.1 2.7 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP78053.1 - 7.6e-05 22.1 0.2 0.00011 21.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 PRP78053.1 - 0.0001 22.0 1.8 0.34 11.1 0.2 3.7 3 0 0 3 3 3 2 Leucine Rich repeat Pkinase PF00069.25 PRP78053.1 - 0.00036 20.0 0.1 0.00051 19.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Amnionless PF14828.6 PRP78053.1 - 0.00062 18.7 0.4 0.00087 18.2 0.4 1.2 1 0 0 1 1 1 1 Amnionless LRR_8 PF13855.6 PRP78053.1 - 0.0054 16.5 5.9 0.021 14.6 2.0 2.8 2 1 0 2 2 2 1 Leucine rich repeat EphA2_TM PF14575.6 PRP78053.1 - 0.0068 17.3 0.7 0.013 16.4 0.7 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 PRP78053.1 - 0.0081 15.5 6.8 0.016 14.6 6.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Orf78 PF06024.12 PRP78053.1 - 0.072 13.4 1.0 0.15 12.4 1.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Cytomega_TRL10 PF06084.11 PRP78053.1 - 0.1 12.7 1.0 3.2 7.8 0.3 2.6 2 1 0 2 2 2 0 Cytomegalovirus TRL10 protein Mid2 PF04478.12 PRP78053.1 - 0.11 12.4 0.8 0.2 11.5 0.8 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4381 PF14316.6 PRP78053.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LRR_1 PF00560.33 PRP78053.1 - 0.11 13.1 1.9 8.9 7.3 0.1 3.6 4 0 0 4 4 3 0 Leucine Rich Repeat FixQ PF05545.11 PRP78053.1 - 0.24 11.4 0.9 0.44 10.6 0.9 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Insulin_TMD PF17870.1 PRP78053.1 - 0.27 11.3 8.1 0.064 13.3 3.5 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 PRP78053.1 - 0.39 10.7 4.3 0.91 9.5 4.3 1.6 1 0 0 1 1 1 0 Syndecan domain ESR1_C PF12743.7 PRP78053.1 - 0.72 9.7 2.7 1.5 8.6 2.7 1.4 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Adeno_E3_CR2 PF02439.15 PRP78053.1 - 0.77 9.6 5.3 2 8.3 5.3 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ATP11 PF06644.11 PRP78055.1 - 1.8e-33 116.5 0.0 2.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 ATP11 protein MCM_bind PF09739.9 PRP78056.1 - 5.1e-131 438.0 0.1 1.9e-129 432.8 0.1 2.0 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 PRP78056.1 - 0.014 15.8 0.1 0.03 14.7 0.1 1.6 1 0 0 1 1 1 0 MCM AAA-lid domain Queuosine_synth PF02547.15 PRP78056.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein Pkinase_Tyr PF07714.17 PRP78057.1 - 1e-73 247.8 0.0 1.5e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78057.1 - 3.8e-51 174.0 0.0 6.5e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP78057.1 - 3.9e-42 141.5 109.3 9e-05 22.8 0.3 18.2 16 3 4 21 21 21 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP78057.1 - 2.8e-40 135.9 104.6 2.3e-08 33.6 4.6 14.2 7 3 9 16 16 16 14 Leucine rich repeat LRR_6 PF13516.6 PRP78057.1 - 5.6e-05 22.9 87.8 1.6 9.0 0.0 22.0 24 0 0 24 24 24 3 Leucine Rich repeat LRR_1 PF00560.33 PRP78057.1 - 0.00021 21.4 89.1 28 5.8 0.0 26.1 26 5 1 27 27 27 0 Leucine Rich Repeat Rax2 PF12768.7 PRP78057.1 - 0.0029 17.1 0.1 0.0029 17.1 0.1 2.4 3 0 0 3 3 3 1 Cortical protein marker for cell polarity LRRNT_2 PF08263.12 PRP78057.1 - 0.0035 17.6 1.4 0.012 15.9 1.4 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Kdo PF06293.14 PRP78057.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP78057.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Inositol_P PF00459.25 PRP78058.1 - 4.7e-40 137.8 0.0 5.7e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family zf-CCCH_4 PF18044.1 PRP78059.1 - 0.061 13.1 4.5 0.19 11.6 4.3 2.0 2 1 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PRP78059.1 - 0.26 11.8 6.9 0.6 10.7 6.9 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger MYCBPAP PF14646.6 PRP78062.1 - 4.2e-27 95.2 7.5 4.2e-27 95.2 7.5 5.0 3 1 0 3 3 3 1 MYCBP-associated protein family BTB PF00651.31 PRP78063.1 - 2.7e-12 46.9 0.9 8.4e-12 45.3 0.9 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-CCCH PF00642.24 PRP78063.1 - 0.00015 21.6 2.0 0.0003 20.6 2.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP78063.1 - 0.0003 20.7 2.1 0.00068 19.6 2.1 1.7 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 PRP78063.1 - 0.00048 20.8 0.1 0.0015 19.2 0.1 1.8 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 PRP78063.1 - 0.0036 17.1 2.4 0.0083 15.9 2.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 PRP78063.1 - 0.046 13.9 2.9 0.18 12.0 2.9 2.0 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 PRP78063.1 - 0.053 14.0 2.3 0.17 12.4 2.3 2.0 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-C4H2 PF10146.9 PRP78064.1 - 0.14 12.5 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein cNMP_binding PF00027.29 PRP78065.1 - 6.3e-36 122.3 0.4 3.1e-18 65.6 0.0 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 PRP78065.1 - 0.00044 19.8 0.1 0.00098 18.7 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP78065.1 - 0.00075 19.6 1.7 0.002 18.2 1.7 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 PRP78065.1 - 0.14 12.0 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pkinase PF00069.25 PRP78066.1 - 3.4e-43 147.9 0.0 3.4e-43 147.9 0.0 2.2 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78066.1 - 5.8e-22 78.2 0.0 5.8e-22 78.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 PRP78066.1 - 0.034 13.1 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 PRP78066.1 - 0.091 12.7 1.5 2.9 7.8 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP78066.1 - 0.48 9.2 21.3 0.012 14.4 13.5 2.2 1 1 0 2 2 2 0 Fungal protein kinase JAB PF01398.21 PRP78067.1 - 2.9e-07 30.5 3.4 3.1e-07 30.4 0.0 2.5 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PRP78067.1 - 0.01 15.6 0.0 0.033 13.9 0.0 1.9 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain TRM13 PF05206.14 PRP78067.1 - 0.062 12.8 4.0 0.11 12.1 4.0 1.3 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF1793 PF08760.11 PRP78067.1 - 0.16 12.4 0.2 0.31 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) SPT16 PF08644.11 PRP78067.1 - 1.1 9.4 6.3 2.5 8.3 6.3 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) GBP_C PF02841.14 PRP78067.1 - 2.3 7.5 17.6 3.8 6.8 17.6 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain MCU PF04678.13 PRP78067.1 - 3.1 7.8 11.0 3.5 7.7 9.9 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter YlqD PF11068.8 PRP78067.1 - 6.7 7.1 17.4 14 6.1 17.4 1.5 1 0 0 1 1 1 0 YlqD protein GCIP PF13324.6 PRP78068.1 - 1.3e-11 44.6 4.5 5.7e-11 42.5 2.9 2.1 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting LIM PF00412.22 PRP78068.1 - 1.8e-07 31.2 5.7 1.8e-07 31.2 5.7 1.9 2 0 0 2 2 2 1 LIM domain Mut7-C PF01927.16 PRP78068.1 - 0.48 10.5 11.0 1.7 8.7 11.0 2.2 1 1 0 1 1 1 0 Mut7-C RNAse domain RecG_N PF17190.4 PRP78070.1 - 0.0096 16.6 0.1 0.06 14.1 0.1 2.0 2 0 0 2 2 2 1 RecG N-terminal helical domain DUF2459 PF09601.10 PRP78070.1 - 0.063 13.1 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) GIY-YIG PF01541.24 PRP78072.1 - 7.4e-06 26.2 0.7 1.8e-05 24.9 0.7 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain Phage_GP20 PF06810.11 PRP78072.1 - 0.051 13.4 0.2 0.2 11.5 0.2 2.0 1 0 0 1 1 1 0 Phage minor structural protein GP20 CdvA PF18822.1 PRP78072.1 - 0.29 10.9 2.6 0.21 11.4 0.5 1.8 2 0 0 2 2 2 0 CdvA-like coiled-coil domain RNase_H PF00075.24 PRP78073.1 - 3.2e-07 30.6 0.0 0.00086 19.5 0.0 2.6 2 0 0 2 2 2 2 RNase H TPR_2 PF07719.17 PRP78073.1 - 0.084 13.0 0.2 0.31 11.3 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP78073.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HEAT PF02985.22 PRP78077.1 - 0.029 14.6 0.1 0.31 11.4 0.0 2.8 4 0 0 4 4 4 0 HEAT repeat TFIID-18kDa PF02269.16 PRP78077.1 - 0.15 12.1 0.3 0.4 10.7 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Sugar_tr PF00083.24 PRP78079.1 - 0.074 11.9 3.9 0.14 11.0 3.9 1.5 1 1 0 1 1 1 0 Sugar (and other) transporter Peptidase_C48 PF02902.19 PRP78080.1 - 2.5e-08 34.1 0.0 2.5e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain JmjC PF02373.22 PRP78080.1 - 1.3e-07 32.1 9.7 5.1e-06 26.9 0.0 3.2 2 1 1 3 3 3 2 JmjC domain, hydroxylase MCM PF00493.23 PRP78081.1 - 2.4e-06 26.8 0.1 3.5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MMR_HSR1 PF01926.23 PRP78081.1 - 3.4e-05 23.9 0.0 8.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 PRP78081.1 - 5.9e-05 22.5 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 PRP78081.1 - 8e-05 22.6 2.2 0.00036 20.5 2.2 1.9 1 1 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 PRP78081.1 - 0.00072 20.1 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 PRP78081.1 - 0.00095 19.4 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PRP78081.1 - 0.00098 19.1 0.3 0.0074 16.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 PRP78081.1 - 0.00099 19.6 0.0 0.0016 19.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PRP78081.1 - 0.0011 19.3 0.1 0.0024 18.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 PRP78081.1 - 0.0026 17.5 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 PRP78081.1 - 0.003 17.8 0.3 0.0057 16.9 0.0 1.6 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 PRP78081.1 - 0.0072 15.9 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 PRP78081.1 - 0.0076 16.5 0.2 0.029 14.6 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 PRP78081.1 - 0.0078 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 PRP78081.1 - 0.0089 16.0 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 NTPase AAA_25 PF13481.6 PRP78081.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PRP78081.1 - 0.015 15.3 0.1 0.032 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 PRP78081.1 - 0.015 14.4 0.2 0.026 13.6 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 PRP78081.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 PRP78081.1 - 0.017 14.3 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.20 PRP78081.1 - 0.025 13.8 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA PF00004.29 PRP78081.1 - 0.029 14.8 0.2 0.065 13.7 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 PRP78081.1 - 0.032 13.7 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein RuvB_N PF05496.12 PRP78081.1 - 0.034 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FeoB_N PF02421.18 PRP78081.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_15 PF13175.6 PRP78081.1 - 0.043 13.5 0.0 0.091 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 PRP78081.1 - 0.047 13.0 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 PRP78081.1 - 0.048 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 PRP78081.1 - 0.053 13.9 0.0 0.083 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 PRP78081.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 PRP78081.1 - 0.068 12.4 0.5 0.13 11.5 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 PRP78081.1 - 0.071 13.2 1.5 2.7 8.0 0.0 2.7 3 0 0 3 3 3 0 Dynamin family DLIC PF05783.11 PRP78081.1 - 0.073 11.9 0.1 0.1 11.4 0.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) IIGP PF05049.13 PRP78081.1 - 0.076 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_7 PF12775.7 PRP78081.1 - 0.077 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 PRP78081.1 - 0.086 12.5 0.1 0.18 11.5 0.1 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 PRP78081.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arf PF00025.21 PRP78081.1 - 0.12 11.8 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Ras PF00071.22 PRP78081.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Ras family Zeta_toxin PF06414.12 PRP78081.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin GTP_EFTU PF00009.27 PRP78081.1 - 0.14 11.7 0.2 0.33 10.5 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 PRP78081.1 - 0.14 11.3 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 PRP78081.1 - 6.6 7.2 9.5 1 9.8 1.5 2.2 1 1 1 2 2 2 0 AAA domain DUF5305 PF17231.2 PRP78082.1 - 0.0049 16.3 0.9 0.0067 15.9 0.9 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5305) AIG1 PF04548.16 PRP78083.1 - 3.8e-15 55.8 0.5 7.8e-15 54.8 0.5 1.5 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PRP78083.1 - 2.2e-06 27.7 0.4 5.3e-06 26.5 0.4 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF87 PF01935.17 PRP78083.1 - 0.0035 17.5 7.0 0.11 12.5 1.0 3.0 2 1 0 2 2 2 2 Helicase HerA, central domain Torsin PF06309.11 PRP78083.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin RRF_GI PF12614.8 PRP78083.1 - 0.21 11.7 2.0 0.42 10.8 2.0 1.4 1 0 0 1 1 1 0 Ribosome recycling factor ABC_tran PF00005.27 PRP78083.1 - 0.38 11.3 0.0 0.38 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter OTU PF02338.19 PRP78084.1 - 0.0036 17.8 0.0 0.0086 16.6 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease RT_RNaseH PF17917.1 PRP78085.1 - 2.5e-35 120.9 0.0 5e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP78085.1 - 1.8e-25 88.9 0.0 3.9e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 PRP78085.1 - 5.8e-14 52.3 0.4 2.1e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.24 PRP78085.1 - 2e-13 50.0 0.3 5.8e-11 42.1 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Integrase_H2C2 PF17921.1 PRP78085.1 - 3.7e-10 39.7 1.5 9.4e-10 38.5 1.5 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain EspB_PE PF18625.1 PRP78085.1 - 0.024 15.1 0.1 13 6.3 0.0 2.4 2 0 0 2 2 2 0 ESX-1 secreted protein B PE domain T7SS_ESX_EspC PF10824.8 PRP78085.1 - 0.089 13.3 0.0 28 5.3 0.0 2.5 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Mtf2_C PF14061.6 PRP78085.1 - 0.2 11.9 1.4 0.47 10.7 0.3 2.1 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 zf-C3HC PF07967.13 PRP78089.1 - 2.6e-26 92.2 0.1 3.7e-22 78.8 0.0 2.7 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 PRP78089.1 - 3.5e-05 23.9 8.4 0.016 15.3 0.0 3.8 3 2 0 3 3 3 2 Rsm1-like CBM_X2 PF03442.14 PRP78090.1 - 0.034 14.2 1.2 6 7.0 0.1 3.6 2 1 1 3 3 3 0 Carbohydrate binding domain X2 DUF5123 PF17161.4 PRP78090.1 - 1.4 10.0 0.0 1.4 10.0 0.0 5.0 5 2 0 5 5 5 0 Domain of unknown function (DUF5123) Pkinase_Tyr PF07714.17 PRP78091.1 - 6.4e-71 238.7 0.0 9.8e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78091.1 - 7.2e-52 176.4 0.0 1.2e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SKG6 PF08693.10 PRP78091.1 - 5e-05 22.6 4.9 0.00013 21.3 4.9 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Haspin_kinase PF12330.8 PRP78091.1 - 0.0062 15.5 1.4 0.093 11.6 0.0 2.8 3 0 0 3 3 3 1 Haspin like kinase domain Kdo PF06293.14 PRP78091.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP78091.1 - 0.033 13.5 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PRP78091.1 - 0.048 12.4 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GvpL_GvpF PF06386.11 PRP78091.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Gly-zipper_YMGG PF13441.6 PRP78091.1 - 9.8 6.0 8.1 0.57 10.0 1.9 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Glyco_hydro_35 PF01301.19 PRP78092.1 - 3.9e-85 286.3 0.0 6.2e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 PRP78092.1 - 1.1e-50 171.0 5.9 1.1e-30 106.5 0.2 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 PRP78092.1 - 8.9e-35 120.1 1.2 1.3e-34 119.6 0.5 1.6 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 PRP78092.1 - 7.8e-13 47.8 0.1 3.2e-12 45.8 0.1 2.1 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Comm PF15957.5 PRP78094.1 - 5.7 7.3 5.1 6.8 7.1 4.0 1.7 1 1 0 1 1 1 0 Commissureless NOA36 PF06524.12 PRP78097.1 - 0.00024 20.5 3.3 0.00048 19.5 3.3 1.4 1 0 0 1 1 1 1 NOA36 protein CDC45 PF02724.14 PRP78097.1 - 0.2 9.9 9.9 0.32 9.2 9.9 1.3 1 0 0 1 1 1 0 CDC45-like protein RasGAP PF00616.19 PRP78097.1 - 0.34 10.6 0.0 0.34 10.6 0.0 2.5 3 0 0 3 3 3 0 GTPase-activator protein for Ras-like GTPase DUF4611 PF15387.6 PRP78097.1 - 0.49 10.6 11.2 1.6 9.0 10.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 PRP78097.1 - 1.6 6.8 10.5 2.7 6.0 10.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Cnd2 PF05786.14 PRP78097.1 - 3.1 6.4 12.7 5.5 5.5 12.7 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 Dicty_REP PF05086.12 PRP78097.1 - 3.2 5.6 6.3 5.1 4.9 6.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MRP-S33 PF08293.11 PRP78097.1 - 3.6 7.9 11.0 0.57 10.5 5.4 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 Adeno_terminal PF02459.15 PRP78097.1 - 8 4.7 7.7 13 4.0 7.7 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Mpp10 PF04006.12 PRP78098.1 - 0.08 11.4 54.0 0.12 10.8 54.0 1.2 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 PRP78098.1 - 0.35 10.2 47.0 0.49 9.7 47.0 1.2 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 PRP78098.1 - 0.45 9.2 28.2 0.68 8.6 28.2 1.2 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 PRP78098.1 - 1.3 8.9 36.1 2.9 7.8 36.1 1.5 1 0 0 1 1 1 0 Spore coat protein CotO SDA1 PF05285.12 PRP78098.1 - 1.7 8.0 65.6 2.6 7.4 65.6 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PRP78098.1 - 1.7 6.7 59.1 2.2 6.4 59.1 1.1 1 0 0 1 1 1 0 Nop14-like family SID-1_RNA_chan PF13965.6 PRP78098.1 - 3.4 6.0 6.3 5.9 5.2 6.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LST1 PF05083.13 PRP78099.1 - 0.012 15.9 0.0 0.048 13.9 0.0 2.1 1 1 0 1 1 1 0 LST-1 protein bZIP_1 PF00170.21 PRP78099.1 - 0.026 14.6 4.8 0.026 14.6 4.8 2.6 1 1 1 2 2 2 0 bZIP transcription factor SKG6 PF08693.10 PRP78099.1 - 0.045 13.2 0.6 0.082 12.3 0.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 PRP78099.1 - 0.068 13.1 0.2 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 Syndecan domain Amnionless PF14828.6 PRP78099.1 - 0.091 11.6 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 PRP78099.1 - 0.1 13.5 0.7 0.25 12.2 0.0 2.0 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM72 PF16054.5 PRP78099.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 72 UPF0242 PF06785.11 PRP78099.1 - 0.16 12.1 16.4 0.67 10.0 16.4 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TssO PF17561.2 PRP78099.1 - 0.62 10.2 3.7 23 5.1 2.5 3.0 2 1 1 3 3 3 0 Type VI secretion system, TssO DUF4446 PF14584.6 PRP78099.1 - 0.99 9.4 5.5 21 5.1 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TMEM51 PF15345.6 PRP78099.1 - 1.8 8.3 13.3 10 5.9 12.6 2.3 1 1 0 1 1 1 0 Transmembrane protein 51 MAP17 PF15807.5 PRP78099.1 - 2.3 8.5 8.0 0.9 9.8 0.1 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF5320 PF17253.2 PRP78099.1 - 3.3 8.8 11.0 12 7.0 0.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) EMP24_GP25L PF01105.24 PRP78099.1 - 3.5 7.5 8.9 8 6.4 9.0 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Med3 PF11593.8 PRP78099.1 - 5.1 6.2 9.9 7.6 5.6 9.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1664 PF07889.12 PRP78099.1 - 6.6 6.8 6.1 12 5.9 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 PRP78099.1 - 6.7 5.7 11.7 5.2 6.1 9.7 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 PRP78099.1 - 8.5 6.9 9.0 4.2 7.8 4.4 2.5 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 PRP78100.1 - 1.6e-50 172.0 0.0 2.8e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78100.1 - 2.1e-50 171.4 0.0 3.3e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.24 PRP78100.1 - 4e-12 46.1 0.1 1.2e-11 44.5 0.2 1.8 2 0 0 2 2 2 1 SH2 domain PH PF00169.29 PRP78100.1 - 4.5e-07 30.3 0.1 1.3e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 PH domain Kdo PF06293.14 PRP78100.1 - 3e-06 26.8 0.0 5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP78100.1 - 0.04 12.9 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Torus PF16131.5 PRP78101.1 - 1.3e-31 109.5 0.5 1.3e-31 109.5 0.5 3.0 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 PRP78101.1 - 1.8e-09 37.3 0.0 5e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_1 PF00536.30 PRP78101.1 - 0.0035 17.8 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-CCCH PF00642.24 PRP78101.1 - 0.01 15.7 3.9 0.022 14.7 3.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.11 PRP78101.1 - 0.014 15.5 0.1 0.014 15.5 0.1 2.4 2 0 0 2 2 2 0 RNA binding motif zf_CCCH_4 PF18345.1 PRP78101.1 - 0.018 15.1 2.8 0.018 15.1 2.8 1.8 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 PRP78101.1 - 0.046 13.5 3.8 0.097 12.5 3.8 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger MMU163 PF17119.5 PRP78101.1 - 0.3 10.2 1.8 7.6 5.6 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis zf-CCCH_2 PF14608.6 PRP78101.1 - 0.5 10.9 1.5 0.83 10.2 1.5 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger UbiA PF01040.18 PRP78102.1 - 1.9e-25 89.6 9.1 2.7e-25 89.1 9.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family U-box PF04564.15 PRP78102.1 - 4e-17 62.2 0.0 8.5e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain SAM_2 PF07647.17 PRP78102.1 - 9.5e-17 60.9 2.2 5.5e-10 39.2 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP78102.1 - 1.3e-13 51.2 1.1 1.7e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 PRP78102.1 - 0.00075 19.7 0.8 0.22 11.8 0.0 2.6 2 0 0 2 2 2 1 Ste50p, sterile alpha motif zf-C2H2_4 PF13894.6 PRP78102.1 - 0.048 14.5 1.9 0.11 13.4 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger SAM_4 PF18017.1 PRP78102.1 - 0.052 13.5 1.5 0.48 10.4 0.0 2.8 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) zf-C2H2 PF00096.26 PRP78102.1 - 0.088 13.3 1.2 0.35 11.4 1.2 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PRP78102.1 - 0.093 12.8 1.1 0.2 11.7 1.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Transgly_assoc PF04226.13 PRP78102.1 - 0.17 12.2 2.3 0.24 11.7 0.9 2.0 2 0 0 2 2 2 0 Transglycosylase associated protein zf-NOSIP PF15906.5 PRP78102.1 - 0.19 11.9 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C2H2_jaz PF12171.8 PRP78102.1 - 0.27 11.6 1.4 0.54 10.6 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PHD PF00628.29 PRP78103.1 - 3.1e-09 36.6 10.7 5.3e-09 35.8 10.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 PRP78103.1 - 0.5 10.0 8.5 0.99 9.0 8.5 1.5 1 0 0 1 1 1 0 PHD-finger RecJ_OB PF17768.1 PRP78104.1 - 0.16 12.2 0.0 0.16 12.2 0.0 1.3 1 1 0 1 1 1 0 RecJ OB domain Lactamase_B_6 PF16661.5 PRP78105.1 - 2.2e-52 177.3 0.0 4.1e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 PRP78105.1 - 3e-20 73.1 0.0 3e-20 73.1 0.0 3.2 2 2 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 PRP78105.1 - 2.3e-14 53.6 0.0 6.2e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 PRP78105.1 - 1.8e-08 34.2 0.0 4.1e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 PRP78105.1 - 3.1e-08 33.9 0.4 6.4e-08 32.8 0.4 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PRP78105.1 - 3.5e-06 26.7 0.1 8.6e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SSB PF00436.25 PRP78105.1 - 0.097 12.7 0.0 0.39 10.8 0.0 2.0 1 0 0 1 1 1 0 Single-strand binding protein family GSDH PF07995.11 PRP78106.1 - 2.2e-18 66.6 0.0 3.8e-16 59.3 0.0 3.1 1 1 1 2 2 2 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 PRP78106.1 - 1.4e-16 60.1 15.2 3.9e-10 39.4 0.5 4.1 3 0 0 3 3 3 2 PKD domain TMEM51 PF15345.6 PRP78106.1 - 0.0011 18.8 4.6 0.0011 18.8 4.6 2.1 2 0 0 2 2 2 1 Transmembrane protein 51 EGF_2 PF07974.13 PRP78106.1 - 0.006 16.9 14.5 0.006 16.9 14.5 7.1 7 0 0 7 7 7 3 EGF-like domain EphA2_TM PF14575.6 PRP78106.1 - 0.043 14.7 0.1 0.45 11.4 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UPF0239 PF06783.11 PRP78106.1 - 0.75 10.0 4.1 0.36 11.0 0.4 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) MAP17 PF15807.5 PRP78106.1 - 5.3 7.3 16.7 0.033 14.4 7.8 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SKG6 PF08693.10 PRP78106.1 - 6.6 6.2 9.3 0.12 11.8 1.8 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain EGF_Tenascin PF18720.1 PRP78106.1 - 7 6.8 76.9 0.93 9.6 3.2 6.0 5 0 0 5 5 5 0 Tenascin EGF domain DUF347 PF03988.12 PRP78106.1 - 8.2 6.7 6.1 5.8 7.2 0.2 2.8 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) WD40 PF00400.32 PRP78107.1 - 6e-10 39.6 7.4 0.014 16.2 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP78107.1 - 0.0027 18.0 0.1 0.78 10.1 0.0 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPIP1 PF15338.6 PRP78107.1 - 0.073 13.2 1.4 0.19 11.8 0.1 2.1 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 GIT_CC PF16559.5 PRP78107.1 - 0.14 12.0 3.5 0.74 9.7 0.1 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMEM215 PF15746.5 PRP78107.1 - 0.82 9.1 7.6 3.2 7.1 1.7 2.7 2 0 0 2 2 2 0 TMEM215 family G6PD_C PF02781.16 PRP78108.1 - 1.2e-111 372.5 0.1 2.2e-111 371.7 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PRP78108.1 - 1.9e-59 201.3 0.6 2.9e-59 200.7 0.0 1.6 2 0 0 2 2 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain CortBP2 PF09727.9 PRP78108.1 - 0.0009 19.2 1.2 0.0019 18.2 1.2 1.5 1 0 0 1 1 1 1 Cortactin-binding protein-2 Val_tRNA-synt_C PF10458.9 PRP78108.1 - 0.0019 18.4 6.1 0.005 17.1 6.1 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm GAS PF13851.6 PRP78108.1 - 0.0074 15.7 3.3 0.016 14.6 3.3 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 PRP78108.1 - 0.012 15.7 2.5 0.027 14.6 2.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor Cluap1 PF10234.9 PRP78108.1 - 0.019 14.3 2.4 0.033 13.6 2.4 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 KASH_CCD PF14662.6 PRP78108.1 - 0.02 14.7 1.9 0.04 13.7 1.9 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PRKG1_interact PF15898.5 PRP78108.1 - 0.025 15.5 1.7 0.087 13.7 1.7 1.9 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Cnn_1N PF07989.11 PRP78108.1 - 0.026 14.7 3.8 0.069 13.3 3.8 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 DHR10 PF18595.1 PRP78108.1 - 0.027 14.5 4.3 0.051 13.6 4.3 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Jnk-SapK_ap_N PF09744.9 PRP78108.1 - 0.029 14.6 4.5 0.067 13.4 4.5 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 PRP78108.1 - 0.052 14.1 1.4 0.13 12.7 1.4 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region SOGA PF11365.8 PRP78108.1 - 0.06 14.5 1.2 0.18 12.9 1.2 1.8 1 0 0 1 1 1 0 Protein SOGA UPF0449 PF15136.6 PRP78108.1 - 0.091 13.2 0.5 0.34 11.4 0.5 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Phage_GPO PF05929.11 PRP78108.1 - 0.098 12.3 1.3 0.24 11.0 1.3 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DivIC PF04977.15 PRP78108.1 - 0.11 12.3 1.8 0.24 11.2 1.8 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF3847 PF12958.7 PRP78108.1 - 0.16 12.1 3.3 0.35 11.0 2.6 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3847) Fusion_gly PF00523.18 PRP78108.1 - 0.25 9.5 0.1 0.37 9.0 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Tmemb_cc2 PF10267.9 PRP78108.1 - 0.34 10.0 4.6 0.22 10.6 2.4 1.6 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein HMMR_C PF15908.5 PRP78108.1 - 0.91 9.8 7.9 0.087 13.1 3.1 1.7 2 0 0 2 2 1 0 Hyaluronan mediated motility receptor C-terminal FAM76 PF16046.5 PRP78108.1 - 1.1 8.6 7.0 0.3 10.4 4.0 1.4 2 0 0 2 2 2 0 FAM76 protein YtxH PF12732.7 PRP78108.1 - 1.5 9.4 6.1 4 8.0 0.2 2.5 2 0 0 2 2 2 0 YtxH-like protein dsrm PF00035.26 PRP78109.1 - 6.5e-15 55.6 0.1 4.9e-09 36.8 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif CN_hydrolase PF00795.22 PRP78110.1 - 7.6e-54 182.8 0.0 9.8e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MBOAT PF03062.19 PRP78111.1 - 5.1e-43 147.8 4.5 5.1e-43 147.8 4.5 2.0 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ThiW PF09512.10 PRP78111.1 - 0.072 13.2 3.5 0.2 11.8 2.3 2.3 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) PQ-loop PF04193.14 PRP78114.1 - 4.1e-20 71.3 9.6 6.5e-14 51.4 0.1 3.1 3 0 0 3 3 3 2 PQ loop repeat RGM_N PF06535.12 PRP78114.1 - 0.2 11.9 0.0 0.26 11.5 0.0 1.1 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus FAM220 PF15487.6 PRP78115.1 - 0.88 9.1 5.7 2.4 7.7 5.7 1.7 1 0 0 1 1 1 0 FAM220 family GDP_Man_Dehyd PF16363.5 PRP78116.1 - 9.8e-96 321.0 0.0 1.1e-95 320.9 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PRP78116.1 - 5.2e-55 186.5 0.0 5.8e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PRP78116.1 - 7.3e-07 28.6 0.0 1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PRP78116.1 - 4.1e-05 22.9 0.0 5.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 PRP78116.1 - 0.018 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Myosin_head PF00063.21 PRP78118.1 - 5.3e-228 758.6 0.0 1.1e-227 757.6 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) LRR_4 PF12799.7 PRP78118.1 - 1.3e-33 114.5 62.9 1.6e-07 31.5 1.1 11.8 9 2 4 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP78118.1 - 1.2e-31 108.2 52.1 1.3e-09 37.7 2.7 8.5 7 1 1 8 8 8 7 Leucine rich repeat LRR_9 PF14580.6 PRP78118.1 - 1.7e-13 50.5 41.5 0.001 18.6 0.1 8.6 9 1 0 9 9 9 7 Leucine-rich repeat LRR_1 PF00560.33 PRP78118.1 - 0.12 13.0 44.9 2.2 9.1 0.4 12.7 14 2 0 14 14 14 0 Leucine Rich Repeat Glyco_hydro_26 PF02156.15 PRP78119.1 - 3.1e-11 43.3 7.0 2.2e-10 40.5 2.8 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 DEAD PF00270.29 PRP78120.1 - 1.4e-46 158.5 0.0 2.1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP78120.1 - 7.3e-19 68.2 0.0 5.5e-18 65.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 PRP78120.1 - 6.2e-05 22.4 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.15 PRP78120.1 - 6.7e-05 23.0 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1590 PF07629.11 PRP78120.1 - 0.064 13.1 0.6 0.16 11.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) Wap1 PF16997.5 PRP78120.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Wap1 domain AAA_19 PF13245.6 PRP78120.1 - 0.11 12.8 0.0 0.39 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain GCH_III PF05165.12 PRP78120.1 - 0.19 10.9 0.0 0.54 9.5 0.0 1.7 1 0 0 1 1 1 0 GTP cyclohydrolase III Glyco_hydro_26 PF02156.15 PRP78121.1 - 5e-11 42.6 8.5 3.2e-10 39.9 2.5 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 DUF3446 PF11928.8 PRP78121.1 - 0.84 10.0 9.3 0.31 11.4 6.1 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain DEAD PF00270.29 PRP78122.1 - 1.4e-46 158.5 0.0 2.1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP78122.1 - 7.3e-19 68.2 0.0 5.5e-18 65.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 PRP78122.1 - 6.2e-05 22.4 0.0 0.00015 21.2 0.0 1.5 1 1 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.15 PRP78122.1 - 6.7e-05 23.0 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1590 PF07629.11 PRP78122.1 - 0.064 13.1 0.6 0.16 11.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) Wap1 PF16997.5 PRP78122.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Wap1 domain AAA_19 PF13245.6 PRP78122.1 - 0.11 12.8 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain GCH_III PF05165.12 PRP78122.1 - 0.2 10.9 0.0 0.54 9.5 0.0 1.6 1 0 0 1 1 1 0 GTP cyclohydrolase III Homeodomain PF00046.29 PRP78123.1 - 1.2e-13 50.7 7.0 2.5e-13 49.7 7.0 1.5 1 0 0 1 1 1 1 Homeodomain Glyco_hydro_26 PF02156.15 PRP78123.1 - 1.1e-08 34.8 12.2 3.5e-08 33.2 3.9 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 26 Abhydrolase_1 PF00561.20 PRP78123.1 - 0.0063 16.2 3.1 1.8 8.1 0.1 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold Homeobox_KN PF05920.11 PRP78123.1 - 0.013 15.4 2.5 0.039 13.9 2.5 1.9 1 0 0 1 1 1 0 Homeobox KN domain DUF648 PF04890.13 PRP78123.1 - 0.16 11.7 0.2 0.28 10.9 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF648) TMEM154 PF15102.6 PRP78123.1 - 4.8 7.1 7.3 17 5.3 7.3 1.9 1 0 0 1 1 1 0 TMEM154 protein family Herpes_capsid PF06112.11 PRP78123.1 - 7 6.7 16.3 16 5.5 16.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pkinase PF00069.25 PRP78125.1 - 5.6e-73 245.6 0.0 6.9e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78125.1 - 4.2e-47 160.6 0.0 5.6e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP78125.1 - 7.8e-05 22.1 0.0 0.00057 19.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 PRP78125.1 - 0.026 14.0 0.0 0.049 13.2 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 PRP78125.1 - 0.13 11.8 0.0 0.99 9.0 0.0 2.1 2 0 0 2 2 2 0 RIO1 family UCH PF00443.29 PRP78126.1 - 1.8e-27 96.5 0.4 1.8e-27 96.5 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP78126.1 - 4.8e-13 49.4 5.2 2.7e-12 46.9 5.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PRP78126.1 - 0.005 16.4 1.1 2.1 7.7 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase Zip PF02535.22 PRP78126.1 - 0.051 12.8 5.1 0.076 12.2 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 PRP78126.1 - 0.2 10.9 17.4 0.3 10.4 17.4 1.1 1 0 0 1 1 1 0 BUD22 Dehalogenase PF13486.6 PRP78126.1 - 0.31 10.4 2.7 0.52 9.6 2.7 1.3 1 0 0 1 1 1 0 Reductive dehalogenase subunit Presenilin PF01080.17 PRP78126.1 - 0.42 9.3 7.8 0.62 8.8 7.8 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 PRP78126.1 - 0.54 8.5 9.0 0.73 8.0 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 PRP78126.1 - 8.2 6.7 19.6 15 5.8 19.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Exo_endo_phos PF03372.23 PRP78127.1 - 3.8e-24 85.5 0.0 1.6e-23 83.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 PRP78127.1 - 3.5e-13 49.1 13.9 3.7e-12 45.8 6.4 2.5 1 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PRP78127.1 - 1.7e-06 28.3 8.3 0.0053 17.1 2.8 3.1 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP78127.1 - 0.0016 18.0 0.4 0.0046 16.5 0.4 1.7 1 1 0 1 1 1 1 Leucine-rich repeat Exo_endo_phos_2 PF14529.6 PRP78127.1 - 0.056 13.3 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Amnionless PF14828.6 PRP78128.1 - 0.044 12.6 0.0 0.096 11.5 0.0 1.5 1 0 0 1 1 1 0 Amnionless Rhomboid PF01694.22 PRP78129.1 - 9.9e-24 84.1 7.1 1.8e-23 83.2 7.1 1.3 1 0 0 1 1 1 1 Rhomboid family COesterase PF00135.28 PRP78130.1 - 3.4e-62 211.0 0.1 1.1e-56 192.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP78130.1 - 0.00059 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP78130.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family YjzC PF14168.6 PRP78131.1 - 0.043 14.2 0.0 0.048 14.0 0.0 1.1 1 0 0 1 1 1 0 YjzC-like protein Pkinase PF00069.25 PRP78133.1 - 9.1e-06 25.2 0.0 9.6e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 PRP78135.1 - 3.5e-51 174.1 0.0 4.2e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78135.1 - 2.3e-27 95.9 0.0 3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP78135.1 - 0.0036 17.3 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP78135.1 - 0.0049 16.5 0.0 0.007 16.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 PRP78135.1 - 0.081 12.2 0.1 0.75 9.1 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 PRP78135.1 - 0.21 10.9 0.1 0.39 10.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PRP78137.1 - 3.6e-45 154.4 0.0 5.9e-44 150.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78137.1 - 1.9e-21 76.6 0.0 2.1e-20 73.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP78137.1 - 0.0026 17.7 0.1 0.0069 16.3 0.0 1.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP78137.1 - 0.04 13.5 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 PRP78137.1 - 0.2 10.9 0.0 0.58 9.4 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 PRP78139.1 - 8.6e-109 363.0 0.0 4.1e-54 183.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78139.1 - 1.3e-60 204.9 0.0 4.9e-29 101.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF1749 PF08538.10 PRP78139.1 - 2e-55 188.0 0.0 3.1e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) APH PF01636.23 PRP78139.1 - 8.2e-10 39.0 0.1 0.00064 19.7 0.0 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP78139.1 - 2.4e-08 33.6 0.5 0.0012 18.3 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP78139.1 - 2.2e-06 27.4 0.0 0.073 12.6 0.0 2.6 2 0 0 2 2 2 2 Choline/ethanolamine kinase Abhydrolase_6 PF12697.7 PRP78139.1 - 2.5e-06 28.3 0.0 6.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP78139.1 - 4.8e-06 26.4 0.1 0.001 18.8 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP78139.1 - 0.0002 20.7 0.0 0.0031 16.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FTA2 PF13095.6 PRP78139.1 - 0.00033 20.3 0.1 0.42 10.2 0.0 2.7 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Ser_hydrolase PF06821.13 PRP78139.1 - 0.00051 19.9 0.0 0.0022 17.9 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Grp7_allergen PF16984.5 PRP78139.1 - 0.0014 18.7 0.0 1.9 8.5 0.0 2.9 3 0 0 3 3 3 2 Group 7 allergen Seadorna_VP7 PF07387.11 PRP78139.1 - 0.0015 17.6 0.0 0.82 8.7 0.1 2.3 2 0 0 2 2 2 2 Seadornavirus VP7 LCAT PF02450.15 PRP78139.1 - 0.0033 16.7 0.1 0.0053 16.0 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 PRP78139.1 - 0.0064 16.0 0.2 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 PRP78139.1 - 0.01 15.2 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Kinase-like PF14531.6 PRP78139.1 - 0.02 14.2 0.1 5.6 6.2 0.0 2.9 2 1 0 2 2 2 0 Kinase-like Sde2_N_Ubi PF13019.6 PRP78139.1 - 0.071 12.9 0.0 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain DUF3530 PF12048.8 PRP78139.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Pox_ser-thr_kin PF05445.11 PRP78139.1 - 0.23 10.4 0.0 18 4.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 PRP78140.1 - 7.8e-52 176.2 0.0 9.1e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78140.1 - 1.5e-24 86.7 0.0 2e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP78140.1 - 0.002 17.5 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP78140.1 - 0.0021 18.0 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP78140.1 - 0.0083 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 PRP78140.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 PRP78141.1 - 1.6e-49 168.7 0.0 2.1e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78141.1 - 1.1e-25 90.4 0.0 1.7e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP78141.1 - 0.00021 20.7 0.1 0.00034 20.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP78141.1 - 0.001 19.1 0.2 0.0024 17.8 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP78141.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 PRP78141.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP78141.1 - 0.2 11.0 0.0 0.45 9.8 0.0 1.7 1 1 0 1 1 1 0 Kinase-like DUF4476 PF14771.6 PRP78143.1 - 2.1e-13 50.4 0.7 3.6e-13 49.6 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) CHCH PF06747.13 PRP78144.1 - 5.5e-06 26.4 2.7 8.5e-06 25.8 2.7 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 PRP78144.1 - 8.5e-05 22.7 12.4 0.0001 22.4 12.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TMEM208_SND2 PF05620.11 PRP78145.1 - 0.5 10.1 3.0 0.47 10.2 0.1 2.4 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 CitMHS PF03600.16 PRP78145.1 - 1.6 7.8 6.5 2.4 7.3 5.7 1.6 1 1 0 1 1 1 0 Citrate transporter SLATT_5 PF18160.1 PRP78146.1 - 0.0044 16.4 0.2 0.0073 15.7 0.0 1.4 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 DSHCT PF08148.12 PRP78146.1 - 0.011 15.4 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain CbtA PF09490.10 PRP78146.1 - 0.075 12.8 2.2 0.1 12.4 0.9 1.7 1 1 1 2 2 2 0 Probable cobalt transporter subunit (CbtA) EMC3_TMCO1 PF01956.16 PRP78146.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Aldedh PF00171.22 PRP78147.1 - 4e-175 582.8 0.0 4.9e-175 582.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 PRP78147.1 - 0.019 14.4 0.0 0.048 13.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Ank_2 PF12796.7 PRP78148.1 - 2.3e-10 40.9 0.0 8.3e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP78148.1 - 1.4e-07 31.2 1.7 0.51 11.1 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat F-box PF00646.33 PRP78148.1 - 7.1e-07 29.0 0.3 1.7e-06 27.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP78148.1 - 1e-06 28.5 0.4 2.2e-06 27.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like Ank_5 PF13857.6 PRP78148.1 - 2.1e-05 24.7 0.7 0.52 10.7 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP78148.1 - 0.0032 18.0 0.7 2.6 8.7 0.0 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) F-box_5 PF18511.1 PRP78148.1 - 0.0044 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box Ank PF00023.30 PRP78148.1 - 0.015 15.7 0.5 16 6.2 0.0 3.6 5 0 0 5 5 5 0 Ankyrin repeat DEAD PF00270.29 PRP78149.1 - 2.6e-49 167.4 0.0 8.4e-49 165.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP78149.1 - 2.7e-28 98.5 0.1 2.4e-25 89.0 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78149.1 - 8.4e-05 22.6 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2325 PF10087.9 PRP78149.1 - 0.17 12.0 0.0 6.5 6.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2325) Pkinase PF00069.25 PRP78150.1 - 1.5e-54 185.2 0.0 1.4e-53 181.9 0.0 2.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78150.1 - 3.1e-29 102.1 0.0 9.3e-29 100.5 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78152.1 - 1.7e-54 185.0 0.0 2.2e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78152.1 - 1.7e-29 102.9 0.0 2.5e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP78152.1 - 0.00071 19.0 0.3 0.0017 17.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP78152.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP78152.1 - 0.0053 16.4 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 PRP78152.1 - 0.066 12.8 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Grp7_allergen PF16984.5 PRP78152.1 - 0.081 13.0 0.1 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Group 7 allergen Kinase-like PF14531.6 PRP78152.1 - 0.12 11.7 0.1 0.85 8.9 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Pkinase PF00069.25 PRP78153.1 - 3e-45 154.7 0.0 5.6e-44 150.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78153.1 - 9e-23 80.9 0.0 1.1e-21 77.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP78153.1 - 0.0029 17.6 0.3 0.0078 16.2 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP78153.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 PRP78153.1 - 0.22 10.9 0.7 0.62 9.4 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1749 PF08538.10 PRP78155.1 - 6.7e-56 189.6 0.0 9.8e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Pkinase PF00069.25 PRP78155.1 - 1.2e-52 178.9 0.0 1.6e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78155.1 - 1.4e-29 103.1 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_1 PF00561.20 PRP78155.1 - 4.2e-07 29.9 0.1 0.00016 21.4 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP78155.1 - 1.6e-06 28.9 0.0 2.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP78155.1 - 0.00011 21.5 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Kdo PF06293.14 PRP78155.1 - 0.00034 20.0 0.1 0.0006 19.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ser_hydrolase PF06821.13 PRP78155.1 - 0.00034 20.5 0.0 0.0011 18.8 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase LCAT PF02450.15 PRP78155.1 - 0.0017 17.6 0.1 0.0027 16.9 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase APH PF01636.23 PRP78155.1 - 0.002 18.1 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF900 PF05990.12 PRP78155.1 - 0.0028 17.2 0.2 0.0066 16.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 PRP78155.1 - 0.0055 16.1 0.1 0.0092 15.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF3530 PF12048.8 PRP78155.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) FTA2 PF13095.6 PRP78155.1 - 0.081 12.5 0.0 0.22 11.1 0.0 1.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Chlorophyllase2 PF12740.7 PRP78155.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 PRP78155.1 - 0.13 11.8 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Grp7_allergen PF16984.5 PRP78155.1 - 0.16 12.0 0.0 0.99 9.4 0.0 2.1 2 0 0 2 2 2 0 Group 7 allergen IR1-M PF12185.8 PRP78155.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Pkinase PF00069.25 PRP78157.1 - 1.9e-55 188.1 0.0 2.4e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78157.1 - 2.3e-30 105.7 0.0 3e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP78157.1 - 2.6e-05 24.3 0.0 0.00013 22.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP78157.1 - 0.0042 16.5 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP78157.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RasGEF PF00617.19 PRP78158.1 - 4.2e-34 118.3 0.0 7.8e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Peptidase_M22 PF00814.25 PRP78160.1 - 7.9e-88 294.7 0.0 9.4e-88 294.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 PRP78160.1 - 0.01 15.5 0.0 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus CNDH2_C PF16858.5 PRP78162.1 - 3.9e-39 135.3 0.0 4.9e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term WRKY PF03106.15 PRP78163.1 - 0.11 12.8 1.1 0.26 11.5 1.1 1.7 1 0 0 1 1 1 0 WRKY DNA -binding domain Pkinase PF00069.25 PRP78164.1 - 1.7e-47 162.0 0.0 2e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78164.1 - 3.2e-16 59.4 0.0 4.2e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP78164.1 - 7.5e-05 22.2 0.1 0.00011 21.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP78164.1 - 0.0005 19.5 0.0 0.00098 18.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 PRP78164.1 - 0.00081 19.4 0.0 0.006 16.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP78164.1 - 0.064 12.8 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Thymidylat_synt PF00303.19 PRP78165.1 - 2.3e-110 368.0 0.0 7.4e-110 366.3 0.0 1.9 2 1 0 2 2 2 1 Thymidylate synthase PRP3 PF08572.10 PRP78166.1 - 0.0089 15.8 1.8 0.0091 15.8 0.1 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) SET PF00856.28 PRP78167.1 - 0.00032 21.1 0.0 0.00081 19.8 0.0 1.7 1 0 0 1 1 1 1 SET domain Rad50_zn_hook PF04423.14 PRP78167.1 - 0.0074 16.1 6.0 0.11 12.4 0.1 3.1 2 1 0 2 2 2 2 Rad50 zinc hook motif THAP PF05485.12 PRP78167.1 - 0.17 12.8 3.4 0.33 11.9 0.2 2.4 2 0 0 2 2 2 0 THAP domain Peptidase_M32 PF02074.15 PRP78168.1 - 7.9e-173 575.7 0.0 9e-173 575.5 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase F_actin_bund_C PF18060.1 PRP78169.1 - 1.4e-21 76.4 1.5 3.2e-21 75.3 1.5 1.6 1 0 0 1 1 1 1 F actin bundling C terminal HR1 PF02185.16 PRP78169.1 - 0.098 12.8 0.9 4.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Hr1 repeat Cation_ATPase_C PF00689.21 PRP78170.1 - 1.3e-46 158.6 5.3 1.3e-46 158.6 5.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PRP78170.1 - 2.4e-39 134.7 1.1 2.4e-39 134.7 1.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PRP78170.1 - 4e-22 79.5 0.2 4.1e-21 76.2 0.1 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP78170.1 - 1.7e-16 60.1 0.0 4.7e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PRP78170.1 - 1.2e-15 56.9 0.0 2.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PRP78170.1 - 4.2e-05 23.4 0.1 0.00066 19.5 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TctB PF07331.11 PRP78170.1 - 0.14 12.4 10.1 0.11 12.7 1.1 3.7 4 0 0 4 4 4 0 Tripartite tricarboxylate transporter TctB family Pkinase_Tyr PF07714.17 PRP78171.1 - 2.9e-52 177.5 0.0 2.7e-50 171.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78171.1 - 5.6e-37 127.5 0.0 6.7e-35 120.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain TIG PF01833.24 PRP78171.1 - 3.4e-11 43.1 6.1 3.4e-11 43.1 6.1 10.3 12 2 1 13 13 13 2 IPT/TIG domain Kdo PF06293.14 PRP78171.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SKG6 PF08693.10 PRP78171.1 - 0.45 10.0 7.1 1.3 8.5 7.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 PRP78171.1 - 0.86 9.5 5.6 2.1 8.2 0.1 2.7 2 0 0 2 2 2 0 TMEM154 protein family RGS-like PF09128.11 PRP78172.1 - 0.12 12.0 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Pkinase PF00069.25 PRP78173.1 - 2.8e-45 154.7 0.0 4.1e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78173.1 - 5.5e-45 153.7 0.0 7.4e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 PRP78173.1 - 9.8e-33 112.6 1.8 3.2e-17 62.9 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PRP78173.1 - 2.7e-29 100.3 4.7 6.7e-06 26.3 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 PRP78173.1 - 1.1e-28 99.2 3.6 4.6e-09 36.6 0.1 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78173.1 - 7.4e-28 93.5 0.2 0.00061 20.1 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 PRP78173.1 - 1.1e-24 86.1 2.4 4.7e-07 29.9 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 PRP78173.1 - 2.5e-05 23.4 0.1 0.00027 20.0 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PRP78173.1 - 0.0017 18.3 0.1 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 PRP78173.1 - 0.068 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CadC_C1 PF18500.1 PRP78175.1 - 0.16 12.1 0.8 23 5.1 0.0 2.4 2 1 0 2 2 2 0 CadC C-terminal domain 1 DUF5052 PF16475.5 PRP78176.1 - 0.015 14.9 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5052) 7TM_GPCR_Srd PF10317.9 PRP78176.1 - 0.026 13.7 0.1 0.034 13.3 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Neurensin PF14927.6 PRP78176.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Neurensin Cas9-BH PF16593.5 PRP78177.1 - 0.064 13.0 0.4 0.089 12.5 0.4 1.2 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 RasGEF PF00617.19 PRP78178.1 - 2.1e-47 161.6 1.7 6.9e-47 159.9 0.4 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP78178.1 - 4.3e-24 84.8 0.9 1.5e-23 83.0 0.9 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif OGG_N PF07934.12 PRP78179.1 - 3e-30 104.8 0.0 5.2e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 PRP78179.1 - 1.7e-16 60.6 0.0 3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PRP78179.1 - 0.00042 20.0 0.0 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF4208 PF13907.6 PRP78179.1 - 0.071 13.6 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Peptidase_M17 PF00883.21 PRP78180.1 - 3.7e-122 407.5 1.5 5.2e-122 407.0 1.5 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 PRP78180.1 - 3.4e-08 33.4 0.7 7.8e-08 32.2 0.7 1.6 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain CMD PF02627.20 PRP78180.1 - 0.13 12.3 1.1 2.7 8.1 0.2 2.5 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Pyr_redox_2 PF07992.14 PRP78181.1 - 7.5e-54 183.0 0.1 9.3e-54 182.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PRP78181.1 - 2.2e-26 92.2 0.0 4.5e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PRP78181.1 - 1.4e-16 60.8 0.2 1e-14 54.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP78181.1 - 1.6e-11 44.1 0.1 4.2e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP78181.1 - 0.00039 19.6 0.5 0.0016 17.6 0.1 2.1 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 PRP78181.1 - 0.0044 16.6 3.2 0.016 14.8 1.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 PRP78181.1 - 0.0051 16.1 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 PRP78181.1 - 0.031 13.6 0.7 2.9 7.1 0.0 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 PRP78181.1 - 0.088 12.1 1.0 0.22 10.9 0.3 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP78181.1 - 0.12 12.6 0.4 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PRP78181.1 - 0.14 12.1 0.7 3.1 7.8 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding T2SSC PF11356.8 PRP78181.1 - 0.15 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system protein C DUF3471 PF11954.8 PRP78181.1 - 0.16 12.5 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) HI0933_like PF03486.14 PRP78181.1 - 0.19 10.4 0.3 1.2 7.8 0.0 2.2 3 0 0 3 3 3 0 HI0933-like protein Grg1 PF11034.8 PRP78182.1 - 1.2e-06 28.6 0.6 3.2e-06 27.3 0.6 1.7 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 FMO-like PF00743.19 PRP78183.1 - 1.3e-20 73.3 0.0 3.1e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 PRP78183.1 - 5.8e-14 52.0 0.1 1.2e-13 51.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PRP78183.1 - 7.9e-12 45.0 0.2 8e-11 41.7 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 PRP78183.1 - 1.4e-11 44.2 2.1 5.3e-10 39.0 1.9 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PRP78183.1 - 2.1e-10 40.3 0.1 2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 PRP78183.1 - 1.5e-07 31.6 3.2 1.5e-07 31.5 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP78183.1 - 1.6e-06 27.9 6.2 7.4e-05 22.5 0.3 2.8 2 1 1 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PRP78183.1 - 8.9e-06 25.2 0.0 0.052 12.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 PRP78183.1 - 1.6e-05 25.4 4.0 0.024 15.2 0.3 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PRP78183.1 - 7.2e-05 22.3 0.3 0.00096 18.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP78183.1 - 0.00024 19.9 5.0 0.0017 17.1 1.3 2.8 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 PRP78183.1 - 0.00069 18.8 2.1 0.00069 18.8 2.1 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 PRP78183.1 - 0.0016 17.6 4.1 0.0042 16.2 0.9 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 PRP78183.1 - 0.0027 17.7 1.1 0.023 14.7 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 PRP78183.1 - 0.0054 17.2 0.0 0.53 10.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 PRP78183.1 - 0.007 15.6 4.0 0.26 10.5 0.6 3.0 3 0 0 3 3 3 1 Thi4 family 3HCDH_N PF02737.18 PRP78183.1 - 0.013 15.3 0.5 0.03 14.2 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PRP78183.1 - 0.11 12.6 0.4 0.21 11.8 0.0 1.6 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Orn_Arg_deC_N PF02784.16 PRP78186.1 - 1.7e-78 263.4 0.0 2.1e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PRP78186.1 - 4.3e-19 68.6 0.0 8.1e-19 67.7 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 PRP78186.1 - 1.3e-06 28.0 0.0 1.5e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel SWIRM PF04433.17 PRP78187.1 - 2.3e-20 72.7 0.0 6.3e-20 71.3 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 PRP78187.1 - 7.2e-12 45.3 0.0 2.9e-11 43.4 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain JAB PF01398.21 PRP78187.1 - 1.6e-08 34.6 0.2 1.6e-08 34.6 0.2 2.8 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PRP78187.1 - 1.6e-06 27.9 0.1 6.9e-06 25.8 0.1 2.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 PRP78187.1 - 8.1e-05 22.8 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF916 PF06030.12 PRP78187.1 - 0.069 13.2 0.4 0.21 11.7 0.4 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Peptidase_M16_C PF05193.21 PRP78188.1 - 4.4e-37 127.9 0.0 1.1e-19 71.2 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PRP78188.1 - 7.8e-30 103.8 1.9 5.3e-22 78.4 0.0 2.9 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Pkinase PF00069.25 PRP78190.1 - 1.8e-70 237.4 0.0 2.3e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78190.1 - 6.6e-51 173.1 0.0 9e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.11 PRP78190.1 - 6.4e-07 29.1 0.0 2.3e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Pkinase_fungal PF17667.1 PRP78190.1 - 7.4e-05 21.7 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP78190.1 - 0.0067 15.8 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP78190.1 - 0.056 12.4 0.0 4.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain GN3L_Grn1 PF08701.11 PRP78191.1 - 0.22 11.6 1.8 1 9.5 1.8 2.2 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase PuR_N PF09182.10 PRP78191.1 - 0.23 11.4 1.2 0.8 9.7 0.4 2.4 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal PRP38 PF03371.15 PRP78191.1 - 0.49 10.3 6.2 1.3 8.9 0.2 3.3 3 0 0 3 3 3 0 PRP38 family UCR_UQCRX_QCR9 PF05365.12 PRP78193.1 - 0.1 12.6 0.9 0.2 11.6 0.9 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RED_N PF07808.13 PRP78194.1 - 1.5e-16 60.8 5.3 8.9e-14 51.6 0.3 4.4 1 1 3 5 5 5 2 RED-like protein N-terminal region RED_C PF07807.11 PRP78194.1 - 0.011 16.2 4.2 0.011 16.2 4.2 4.9 4 2 1 5 5 5 0 RED-like protein C-terminal region PIN_8 PF18476.1 PRP78194.1 - 0.04 13.8 0.2 0.04 13.8 0.2 4.0 3 1 1 4 4 4 0 PIN like domain DUF5345 PF17280.2 PRP78194.1 - 2.7 8.0 10.7 2 8.5 1.8 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Rhodanese PF00581.20 PRP78195.1 - 0.00016 22.2 0.0 0.0004 20.9 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain MMR_HSR1 PF01926.23 PRP78196.1 - 7e-08 32.6 0.1 1.3e-07 31.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF697 PF05128.12 PRP78196.1 - 0.0036 17.0 3.3 0.0085 15.8 3.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF697) Arf PF00025.21 PRP78196.1 - 0.037 13.5 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.18 PRP78196.1 - 0.042 13.4 0.2 0.1 12.1 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AadA_C PF18280.1 PRP78196.1 - 0.093 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Aminoglycoside adenyltransferase C-terminal domain PDEase_I PF00233.19 PRP78198.1 - 2.6e-83 279.4 6.0 5.2e-83 278.4 6.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 PRP78198.1 - 2.5e-63 212.6 0.0 3.7e-20 72.9 0.0 5.1 5 0 0 5 5 5 4 GAF domain GAF_2 PF13185.6 PRP78198.1 - 1.4e-44 151.8 0.0 9.3e-12 45.4 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 PRP78198.1 - 4.9e-30 104.5 0.0 1e-08 35.6 0.0 4.8 4 1 0 4 4 4 4 GAF domain dCache_1 PF02743.18 PRP78198.1 - 9e-08 32.2 2.0 0.00076 19.3 0.0 5.1 5 0 0 5 5 5 1 Cache domain TMF_DNA_bd PF12329.8 PRP78198.1 - 0.00072 19.5 8.6 0.0037 17.2 8.6 2.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding H_kinase_N PF12282.8 PRP78198.1 - 0.0027 17.7 0.0 26 4.8 0.0 3.7 3 0 0 3 3 3 0 Signal transduction histidine kinase FANCI_HD1 PF14679.6 PRP78198.1 - 0.016 15.1 1.2 2 8.5 0.1 3.1 2 0 0 2 2 2 0 FANCI helical domain 1 Lebercilin PF15619.6 PRP78198.1 - 0.26 10.9 19.8 1.5 8.4 17.9 2.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF469 PF04320.14 PRP78198.1 - 0.33 11.9 1.7 1.9 9.4 0.1 3.0 3 0 0 3 3 2 0 Protein with unknown function (DUF469) CorA PF01544.18 PRP78198.1 - 0.65 9.2 9.8 0.68 9.2 7.9 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein SlyX PF04102.12 PRP78198.1 - 1.1 9.9 8.3 14 6.3 0.7 3.2 2 0 0 2 2 2 0 SlyX CLZ PF16526.5 PRP78198.1 - 3.9 7.9 7.8 0.31 11.4 1.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DSHCT PF08148.12 PRP78199.1 - 3.3e-49 166.7 0.9 6.9e-49 165.7 0.9 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 PRP78199.1 - 1.8e-38 133.1 2.5 1.8e-38 133.1 2.5 2.3 2 0 0 2 2 2 1 rRNA-processing arch domain Ski2_N PF17911.1 PRP78199.1 - 3e-18 65.9 0.2 9e-18 64.4 0.2 1.7 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 PRP78199.1 - 8.5e-18 64.7 0.0 2.8e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP78199.1 - 7.3e-07 29.5 0.0 2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78199.1 - 0.00022 21.3 0.0 0.00064 19.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_Tnp_ISL3 PF13542.6 PRP78199.1 - 0.1 12.0 1.8 13 5.2 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 FKBP_C PF00254.28 PRP78200.1 - 1.5e-16 60.5 0.0 2.6e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase p450 PF00067.22 PRP78201.1 - 3.5e-66 223.9 0.0 5.5e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 PRP78201.1 - 8.2e-29 100.8 0.0 1.5e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PRP78201.1 - 1.9e-19 70.3 0.5 1.9e-18 67.0 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 PRP78201.1 - 1.1e-15 58.2 0.0 4.5e-15 56.2 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PRP78201.1 - 0.12 12.7 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain ABC_membrane PF00664.23 PRP78202.1 - 2e-114 381.9 14.1 2.7e-57 194.5 5.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP78202.1 - 9.3e-68 227.0 0.0 1.2e-32 113.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PRP78202.1 - 3.3e-14 52.8 5.2 5e-05 22.8 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PRP78202.1 - 2e-08 33.5 0.3 0.00024 20.0 0.2 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 PRP78202.1 - 5.6e-07 29.2 0.3 0.03 14.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PRP78202.1 - 5.7e-07 29.6 0.0 0.017 15.0 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PRP78202.1 - 4.6e-06 27.1 5.1 0.017 15.5 0.4 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 PRP78202.1 - 6.4e-06 26.0 1.6 0.04 13.6 0.4 3.5 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 PRP78202.1 - 5.5e-05 23.5 1.6 0.19 12.0 0.2 3.8 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 PRP78202.1 - 8.8e-05 21.9 2.2 0.082 12.2 0.0 3.2 4 0 0 4 4 4 2 Zeta toxin AAA_25 PF13481.6 PRP78202.1 - 0.00026 20.6 0.4 1 8.9 0.0 4.0 5 0 0 5 5 4 1 AAA domain G-alpha PF00503.20 PRP78202.1 - 0.00051 19.3 0.0 0.47 9.6 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_33 PF13671.6 PRP78202.1 - 0.00067 19.8 0.0 1.2 9.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PRP78202.1 - 0.0015 18.1 0.0 0.58 9.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 PRP78202.1 - 0.0015 18.7 5.9 1.7 9.0 0.8 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 PRP78202.1 - 0.0027 17.6 1.0 17 5.1 0.1 4.1 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 PRP78202.1 - 0.0053 16.8 0.6 6 6.9 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 PRP78202.1 - 0.012 15.3 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 PRP78202.1 - 0.013 15.6 0.6 3.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 PRP78202.1 - 0.021 14.9 0.6 11 6.1 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_18 PF13238.6 PRP78202.1 - 0.028 15.0 0.0 5.6 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 PRP78202.1 - 0.029 14.1 0.0 0.8 9.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 PRP78202.1 - 0.031 13.4 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 PRP78202.1 - 0.045 14.3 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 PRP78202.1 - 0.059 13.1 0.0 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 PRP78202.1 - 0.076 13.4 0.3 20 5.7 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Rad17 PF03215.15 PRP78202.1 - 0.078 12.9 0.1 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 PRP78202.1 - 0.1 12.5 2.6 15 5.5 0.0 3.2 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 PRP78202.1 - 0.1 11.8 0.2 9.7 5.3 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 PRP78202.1 - 0.11 12.9 0.7 6.7 7.0 0.1 3.8 4 1 0 4 4 4 0 AAA domain APS_kinase PF01583.20 PRP78202.1 - 0.16 11.9 0.4 7.9 6.3 0.0 2.8 3 0 0 3 3 2 0 Adenylylsulphate kinase p450 PF00067.22 PRP78203.1 - 5.1e-72 243.1 0.0 7.3e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 PRP78203.1 - 2.3e-28 99.3 0.0 4.2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PRP78203.1 - 3.1e-20 72.8 0.5 2.8e-19 69.7 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 PRP78203.1 - 9.2e-16 58.4 0.1 3.1e-15 56.7 0.1 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FKBP_C PF00254.28 PRP78204.1 - 1.8e-16 60.3 0.0 3.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DSHCT PF08148.12 PRP78205.1 - 3.3e-49 166.7 0.9 6.9e-49 165.7 0.9 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 PRP78205.1 - 1.8e-38 133.1 2.5 1.8e-38 133.1 2.5 2.3 2 0 0 2 2 2 1 rRNA-processing arch domain Ski2_N PF17911.1 PRP78205.1 - 3e-18 65.9 0.2 9e-18 64.4 0.2 1.7 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 PRP78205.1 - 8.5e-18 64.7 0.0 2.8e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP78205.1 - 7.3e-07 29.5 0.0 2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78205.1 - 0.00022 21.3 0.0 0.00064 19.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_Tnp_ISL3 PF13542.6 PRP78205.1 - 0.1 12.0 1.8 13 5.2 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 PDEase_I PF00233.19 PRP78206.1 - 2.5e-83 279.5 6.0 4.1e-83 278.8 6.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 PRP78206.1 - 1e-63 213.9 0.0 3e-20 73.2 0.0 5.0 5 0 0 5 5 5 4 GAF domain GAF_2 PF13185.6 PRP78206.1 - 6.1e-45 152.9 0.0 7.5e-12 45.7 0.0 4.4 4 0 0 4 4 4 4 GAF domain GAF_3 PF13492.6 PRP78206.1 - 2.2e-30 105.6 0.0 8.5e-09 35.8 0.0 4.8 4 1 0 4 4 4 4 GAF domain dCache_1 PF02743.18 PRP78206.1 - 3.4e-07 30.3 0.0 0.00062 19.6 0.0 4.2 4 0 0 4 4 4 1 Cache domain H_kinase_N PF12282.8 PRP78206.1 - 0.0016 18.4 0.0 22 5.0 0.0 3.6 3 0 0 3 3 3 0 Signal transduction histidine kinase SpoVT_C PF15714.5 PRP78206.1 - 0.0017 18.4 0.1 0.64 10.1 0.0 4.0 5 0 0 5 5 5 1 Stage V sporulation protein T C-terminal, transcription factor FANCI_HD1 PF14679.6 PRP78206.1 - 0.015 15.2 1.2 1.6 8.7 0.1 2.8 2 0 0 2 2 2 0 FANCI helical domain 1 DUF469 PF04320.14 PRP78206.1 - 0.13 13.1 0.2 1.6 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein with unknown function (DUF469) DUF2111 PF09884.9 PRP78206.1 - 0.17 11.9 0.3 3 8.0 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2111) Chromo PF00385.24 PRP78207.1 - 0.00012 21.9 0.2 0.00019 21.3 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TPALS PF18178.1 PRP78208.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family ZZ PF00569.17 PRP78209.1 - 2.9e-06 27.0 12.4 7.8e-06 25.6 12.4 1.6 1 1 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.20 PRP78209.1 - 0.049 13.8 6.7 0.07 13.3 6.0 1.7 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) TehB PF03848.14 PRP78210.1 - 7.9e-12 45.0 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 PRP78210.1 - 1.3e-09 38.6 0.0 2.6e-08 34.4 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP78210.1 - 1.3e-06 28.9 0.0 3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP78210.1 - 5.5e-06 26.2 0.0 8.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP78210.1 - 2.7e-05 24.1 0.0 6.3e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP78210.1 - 3.4e-05 24.5 0.0 0.00082 20.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 PRP78210.1 - 0.00064 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 PRP78210.1 - 0.016 14.8 0.0 0.039 13.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Rhodanese PF00581.20 PRP78210.1 - 0.019 15.5 0.0 0.064 13.8 0.0 1.9 2 0 0 2 2 2 0 Rhodanese-like domain DUF938 PF06080.12 PRP78210.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.6 PRP78210.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Podoplanin PF05808.11 PRP78211.1 - 0.00016 21.8 0.3 0.00016 21.8 0.3 2.6 2 1 0 2 2 2 1 Podoplanin TMEM154 PF15102.6 PRP78211.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 3.3 2 1 1 3 3 3 1 TMEM154 protein family DUF4448 PF14610.6 PRP78211.1 - 0.0081 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Apt1 PF10351.9 PRP78211.1 - 0.08 11.8 11.2 0.15 10.9 10.8 1.6 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF3827 PF12877.7 PRP78211.1 - 0.11 10.8 0.0 0.11 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) DUF5385 PF17359.2 PRP78211.1 - 0.14 11.7 0.3 0.25 10.9 0.1 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF5385) Insulin_TMD PF17870.1 PRP78211.1 - 0.26 11.4 4.5 0.09 12.9 1.0 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Shisa PF13908.6 PRP78211.1 - 3.3 7.9 0.0 3.3 7.9 0.0 3.2 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Homeobox_KN PF05920.11 PRP78213.1 - 1.3e-10 41.0 0.8 3.3e-10 39.7 0.8 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PRP78213.1 - 9.3e-08 31.8 0.2 2.3e-07 30.5 0.2 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP78214.1 - 2.9e-13 49.5 0.3 5.6e-13 48.6 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PRP78214.1 - 1.3e-07 31.4 0.2 2.5e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PRP78214.1 - 0.0029 17.0 0.0 0.0096 15.4 0.0 1.8 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Hormone_2 PF00123.20 PRP78214.1 - 0.059 13.3 0.4 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Peptide hormone COX4 PF02936.14 PRP78214.1 - 0.077 13.0 0.5 0.2 11.7 0.2 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV CorA PF01544.18 PRP78215.1 - 2e-55 188.2 1.8 4.1e-55 187.2 1.8 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_S8 PF00082.22 PRP78216.1 - 1.3e-12 47.6 7.6 1.3e-12 47.6 7.6 2.0 2 0 0 2 2 2 1 Subtilase family Pkinase_Tyr PF07714.17 PRP78217.1 - 1.2e-66 224.7 0.0 2.1e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78217.1 - 1.6e-49 168.7 0.0 2.9e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP78217.1 - 0.00068 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP78217.1 - 0.0017 17.8 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ubiquitin PF00240.23 PRP78218.1 - 5.6e-05 22.8 1.4 0.00024 20.8 1.4 2.0 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP78218.1 - 0.0067 16.2 0.4 0.023 14.5 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF4699 PF15770.5 PRP78218.1 - 0.16 11.7 0.1 12 5.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4699) DUF4536 PF15055.6 PRP78219.1 - 0.027 14.7 3.7 0.054 13.7 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4536) Clat_adaptor_s PF01217.20 PRP78220.1 - 3.3e-43 147.0 3.7 6.5e-43 146.1 3.7 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain PABP PF00658.18 PRP78220.1 - 0.035 14.3 0.0 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain Dodecin PF07311.12 PRP78221.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Dodecin Presenilin PF01080.17 PRP78221.1 - 5.2 5.7 6.6 7.5 5.2 6.6 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 PRP78221.1 - 8.1 6.2 8.5 16 5.2 8.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Brr6_like_C_C PF10104.9 PRP78222.1 - 0.65 9.8 1.9 0.93 9.3 1.9 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Membralin PF09746.9 PRP78222.1 - 3.9 6.4 5.4 4.1 6.3 5.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein RhoGEF PF00621.20 PRP78223.1 - 4.8e-45 154.0 0.8 4.8e-45 154.0 0.8 2.4 3 0 0 3 3 3 1 RhoGEF domain tRNA_m1G_MT PF01746.21 PRP78224.1 - 1.9e-23 83.2 0.1 3.9e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Eapp_C PF10238.9 PRP78224.1 - 4.5 7.3 10.6 7.9 6.5 2.1 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein SOBP PF15279.6 PRP78224.1 - 6.3 7.3 7.7 0.6 10.7 2.1 1.9 1 1 1 2 2 2 0 Sine oculis-binding protein Pkinase PF00069.25 PRP78225.1 - 1.9e-48 165.1 0.5 2.4e-48 164.8 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78225.1 - 1.1e-22 80.6 0.6 1.4e-22 80.3 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP78225.1 - 1.3e-05 24.6 0.3 2.3e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP78225.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PI3_PI4_kinase PF00454.27 PRP78225.1 - 0.003 17.4 1.7 0.0075 16.1 1.7 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1223 PF06764.11 PRP78225.1 - 0.013 15.5 0.5 0.024 14.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) Tubulin PF00091.25 PRP78227.1 - 3.5e-52 177.5 0.1 5.9e-52 176.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 PRP78227.1 - 0.0011 18.3 0.7 0.016 14.4 0.7 2.1 1 1 0 1 1 1 1 Tubulin like Na_H_Exchanger PF00999.21 PRP78229.1 - 1e-55 189.1 40.7 9.2e-55 186.0 41.3 1.9 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family LRR_8 PF13855.6 PRP78229.1 - 3.6e-26 90.7 34.0 1e-09 38.0 2.7 5.7 3 1 2 5 5 5 5 Leucine rich repeat Pkinase PF00069.25 PRP78229.1 - 1.9e-17 63.5 0.6 1.6e-11 44.1 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78229.1 - 7.9e-17 61.4 0.3 1.1e-09 38.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PRP78229.1 - 1.8e-15 56.8 41.5 0.00032 21.0 1.3 7.6 7 0 0 7 7 7 5 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP78229.1 - 1e-08 35.6 2.9 2.1e-08 34.6 2.9 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP78229.1 - 1.3e-05 25.1 35.5 3.5 8.5 0.1 10.2 9 1 1 10 10 10 4 Leucine Rich Repeat LRR_6 PF13516.6 PRP78229.1 - 0.67 10.2 9.2 23 5.4 0.0 6.2 5 0 0 5 5 5 0 Leucine Rich repeat DHO_dh PF01180.21 PRP78231.1 - 1.4e-32 113.1 0.0 6.8e-32 110.9 0.0 2.1 3 0 0 3 3 3 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.6 PRP78231.1 - 1.6e-22 79.4 13.2 1.6e-22 79.4 13.2 2.8 3 0 0 3 3 2 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 PRP78231.1 - 2.1e-14 53.5 0.0 3.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 PRP78231.1 - 6.4e-09 35.6 0.0 6.4e-09 35.6 0.0 2.8 2 1 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Dus PF01207.17 PRP78231.1 - 2.6e-06 26.7 0.0 5.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Fer4 PF00037.27 PRP78231.1 - 6.4e-06 25.8 20.1 0.005 16.6 4.1 3.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_10 PF13237.6 PRP78231.1 - 1.3e-05 25.2 8.4 1.3e-05 25.2 8.4 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 PRP78231.1 - 1.3e-05 25.6 9.2 1.3e-05 25.6 9.2 2.6 2 0 0 2 2 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 PRP78231.1 - 6.3e-05 23.5 0.0 0.044 14.4 0.0 3.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_6 PF12837.7 PRP78231.1 - 0.00013 21.9 1.5 0.00013 21.9 1.5 3.6 3 1 1 4 4 3 2 4Fe-4S binding domain NAD_binding_8 PF13450.6 PRP78231.1 - 0.00053 20.2 0.0 0.0024 18.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PRP78231.1 - 0.00064 19.1 0.0 0.9 8.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.6 PRP78231.1 - 0.001 19.2 11.6 0.001 19.2 11.6 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 PRP78231.1 - 0.0038 17.2 14.0 0.0097 16.0 2.5 3.8 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 PRP78231.1 - 0.011 16.1 9.0 0.2 12.1 1.7 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 PRP78231.1 - 0.014 16.0 13.0 0.33 11.5 2.7 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 PRP78231.1 - 0.026 15.0 11.7 0.38 11.3 1.3 3.1 3 0 0 3 3 2 0 4Fe-4S dicluster domain AlaDh_PNT_C PF01262.21 PRP78231.1 - 0.032 13.5 0.0 2.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 PRP78231.1 - 0.033 14.3 0.0 8.2 6.5 0.0 3.2 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.13 PRP78231.1 - 0.07 13.1 0.0 4.1 7.3 0.0 3.3 4 0 0 4 4 4 0 Glycosyl transferase WecB/TagA/CpsF family Fer4_15 PF13459.6 PRP78231.1 - 3.1 8.6 10.3 7.6 7.4 0.3 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_22 PF17179.4 PRP78231.1 - 8.7 7.3 17.7 1.7 9.5 0.2 3.5 4 0 0 4 4 2 0 4Fe-4S dicluster domain C2 PF00168.30 PRP78232.1 - 6.3e-37 126.0 0.5 1.1e-20 73.8 0.2 2.8 2 0 0 2 2 2 2 C2 domain Pkinase_Tyr PF07714.17 PRP78232.1 - 6.2e-28 97.8 1.0 6.2e-28 97.8 1.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase GRAM PF02893.20 PRP78232.1 - 2.9e-27 94.8 0.9 6.8e-14 51.7 0.2 2.8 2 0 0 2 2 2 2 GRAM domain Pkinase PF00069.25 PRP78232.1 - 2.8e-19 69.5 1.0 2.8e-19 69.5 1.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Membr_traf_MHD PF10540.9 PRP78232.1 - 0.00029 21.0 0.4 0.059 13.6 0.7 3.0 1 1 1 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain PH_TFIIH PF08567.11 PRP78232.1 - 0.0034 17.7 0.0 5.5 7.4 0.0 3.0 2 0 0 2 2 2 2 TFIIH p62 subunit, N-terminal domain ABC1 PF03109.16 PRP78232.1 - 0.053 13.7 0.0 1.9 8.6 0.0 2.9 2 1 0 2 2 2 0 ABC1 family Syndecan PF01034.20 PRP78232.1 - 1.9 8.5 4.2 1 9.4 0.8 2.2 2 0 0 2 2 2 0 Syndecan domain Retrotrans_gag PF03732.17 PRP78233.1 - 5.5e-05 23.4 0.6 5.5e-05 23.4 0.6 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein F-box-like PF12937.7 PRP78235.1 - 4.2e-11 42.6 1.0 2.3e-10 40.2 0.6 2.4 2 0 0 2 2 2 1 F-box-like zf-UBR PF02207.20 PRP78235.1 - 0.00012 22.2 11.4 0.00033 20.8 11.4 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.33 PRP78235.1 - 0.00029 20.6 0.2 0.00067 19.5 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP78235.1 - 0.022 14.7 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 F-box ABC_tran PF00005.27 PRP78236.1 - 8.1e-53 178.6 0.0 9e-31 107.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 PRP78236.1 - 1.3e-45 156.2 30.2 6.5e-29 101.4 10.7 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 PRP78236.1 - 2.5e-09 36.9 7.0 0.0037 16.7 0.2 4.3 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PRP78236.1 - 1.7e-07 31.3 0.6 0.02 15.0 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PRP78236.1 - 8.8e-06 26.2 0.8 0.016 15.6 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 PRP78236.1 - 1.5e-05 25.2 1.0 0.0036 17.4 0.1 2.6 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 PRP78236.1 - 2.3e-05 24.0 1.1 0.073 12.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PRP78236.1 - 0.00016 21.6 1.6 1.6 8.5 0.2 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 PRP78236.1 - 0.00046 20.0 0.4 0.046 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PRP78236.1 - 0.00049 20.0 0.5 0.57 10.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 PRP78236.1 - 0.002 17.0 0.2 0.71 8.6 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 PRP78236.1 - 0.0021 17.7 1.2 0.041 13.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 PRP78236.1 - 0.0054 16.9 4.4 0.83 9.7 0.4 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 PRP78236.1 - 0.011 15.2 0.2 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 PRP78236.1 - 0.012 15.2 0.4 3 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 PRP78236.1 - 0.012 15.4 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 PRP78236.1 - 0.014 15.9 0.5 7.6 7.0 0.2 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PRP78236.1 - 0.054 12.5 2.4 0.34 9.9 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.6 PRP78236.1 - 0.058 13.7 3.5 7.8 6.8 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PRP78236.1 - 0.089 13.0 0.2 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF2407_C PF13373.6 PRP78236.1 - 0.089 13.0 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 DUF2407 C-terminal domain cobW PF02492.19 PRP78236.1 - 0.12 12.0 0.8 1.6 8.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 PRP78236.1 - 0.17 11.6 4.4 14 5.3 1.3 3.0 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PRP78236.1 - 0.26 10.6 0.9 7.9 5.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 PRP78236.1 - 4.7 6.8 5.3 8.4 6.0 0.2 2.6 3 0 0 3 3 2 0 AAA ATPase domain DUF1720 PF08226.11 PRP78238.1 - 0.52 10.8 11.6 1 9.8 11.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) LCAT PF02450.15 PRP78239.1 - 9e-58 196.3 0.2 1.3e-57 195.8 0.2 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ank_4 PF13637.6 PRP78239.1 - 8.9e-16 58.1 1.2 4.7e-06 27.0 0.2 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP78239.1 - 2e-14 53.9 0.1 5.9e-06 26.8 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 PRP78239.1 - 1.2e-12 47.7 0.1 6e-05 23.3 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP78239.1 - 1.2e-10 41.4 0.2 0.0012 19.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78239.1 - 7.9e-10 38.1 0.5 0.0043 17.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Lipase_2 PF01674.18 PRP78239.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) NKWYS PF10364.9 PRP78239.1 - 0.27 11.4 0.9 11 6.2 0.1 2.4 2 0 0 2 2 2 0 Putative capsular polysaccharide synthesis protein Glyco_hydro_18 PF00704.28 PRP78240.1 - 4.6e-21 75.9 1.6 1.3e-10 41.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP78240.1 - 1.4e-18 67.0 76.9 2e-07 31.4 18.3 3.6 3 1 0 3 3 3 3 Chitin recognition protein Ank_2 PF12796.7 PRP78241.1 - 0.00064 20.3 0.1 1.1 9.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Methyltransf_25 PF13649.6 PRP78241.1 - 0.0051 17.5 0.0 0.013 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ank_4 PF13637.6 PRP78241.1 - 0.0098 16.5 0.0 0.19 12.4 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_11 PF08241.12 PRP78241.1 - 0.013 16.1 0.0 0.031 14.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ank_3 PF13606.6 PRP78241.1 - 0.09 13.4 0.0 0.56 11.0 0.0 2.3 3 0 0 3 3 3 0 Ankyrin repeat FAM209 PF15206.6 PRP78241.1 - 0.26 11.1 4.4 1.1 9.1 0.5 2.5 1 1 1 2 2 2 0 FAM209 family Hairy_orange PF07527.13 PRP78242.1 - 0.052 13.8 0.5 0.088 13.0 0.5 1.4 1 0 0 1 1 1 0 Hairy Orange DFF40 PF09230.10 PRP78242.1 - 0.081 12.5 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa TACC_C PF05010.14 PRP78244.1 - 0.057 13.2 13.8 0.025 14.4 11.2 1.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-C4H2 PF10146.9 PRP78244.1 - 0.09 13.1 9.5 0.12 12.7 9.5 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Glutaredoxin2_C PF04399.13 PRP78244.1 - 0.099 12.5 2.7 0.65 9.8 0.5 2.3 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain eIF-4B PF06273.11 PRP78244.1 - 0.7 8.9 7.3 1.1 8.3 7.3 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B TMPIT PF07851.13 PRP78244.1 - 3.9 6.6 9.9 3.4 6.8 8.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein RF-1 PF00472.20 PRP78244.1 - 5.4 7.0 9.4 0.76 9.7 3.8 2.1 2 0 0 2 2 2 0 RF-1 domain Exonuc_VII_L PF02601.15 PRP78244.1 - 6.4 6.3 8.3 8.5 5.8 8.3 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit RIO1 PF01163.22 PRP78245.1 - 3.6e-45 153.9 0.0 8.1e-45 152.7 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 PRP78245.1 - 1.4e-32 111.7 0.1 2.9e-32 110.7 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 PRP78245.1 - 2.3e-08 34.2 0.7 0.00025 21.0 0.0 3.2 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP78245.1 - 7.6e-05 22.2 2.2 0.2 11.0 0.0 3.0 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family FAM176 PF14851.6 PRP78245.1 - 0.76 9.4 6.2 1.3 8.7 6.2 1.4 1 0 0 1 1 1 0 FAM176 family Spt5_N PF11942.8 PRP78245.1 - 1.1 10.3 11.2 2.1 9.4 11.2 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 PRP78245.1 - 4 7.9 13.8 12 6.4 13.8 1.8 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 PRP78245.1 - 4.1 6.7 9.0 0.18 11.1 0.8 2.7 3 1 0 3 3 3 0 Protein kinase domain Pkinase PF00069.25 PRP78246.1 - 1e-29 103.8 0.0 1.7e-29 103.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78246.1 - 2.1e-08 33.8 0.0 4.9e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP78246.1 - 0.03 13.7 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP78246.1 - 0.078 12.9 0.0 8.3 6.3 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4020 PF13212.6 PRP78246.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) Retrotrans_gag PF03732.17 PRP78249.1 - 1.2e-05 25.5 0.0 2.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Chromo PF00385.24 PRP78250.1 - 1.3e-08 34.7 0.0 2.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Zincin_1 PF06262.11 PRP78250.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Mtf2_C PF14061.6 PRP78250.1 - 0.14 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 zf-U1 PF06220.12 PRP78251.1 - 2.6e-20 71.9 4.2 3.8e-20 71.4 4.2 1.3 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 PRP78251.1 - 0.0097 15.8 1.5 0.016 15.1 1.5 1.4 1 0 0 1 1 1 1 CLIP1 zinc knuckle Sar8_2 PF03058.14 PRP78252.1 - 0.038 14.5 0.0 0.069 13.7 0.0 1.4 1 0 0 1 1 1 0 Sar8.2 family Bromodomain PF00439.25 PRP78253.1 - 1.1e-13 51.0 0.1 2.8e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Bromodomain SAP PF02037.27 PRP78253.1 - 3.3e-08 33.1 0.6 7.2e-08 32.0 0.6 1.6 1 0 0 1 1 1 1 SAP domain FHA PF00498.26 PRP78253.1 - 3.5e-07 30.5 0.0 6.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PRP78253.1 - 0.048 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 PRP78253.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 FHA domain Tubulin PF00091.25 PRP78255.1 - 3.5e-52 177.5 0.1 5.9e-52 176.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 PRP78255.1 - 0.0011 18.3 0.7 0.016 14.4 0.7 2.1 1 1 0 1 1 1 1 Tubulin like LRR_8 PF13855.6 PRP78257.1 - 1.4e-25 88.8 40.3 2.8e-09 36.6 5.2 6.2 2 1 6 8 8 8 8 Leucine rich repeat Pkinase PF00069.25 PRP78257.1 - 3.7e-18 65.9 0.7 5.9e-12 45.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78257.1 - 1.1e-17 64.2 0.3 3.6e-10 39.6 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PRP78257.1 - 4.9e-16 58.6 43.4 0.00015 22.1 1.3 7.8 6 1 0 7 7 7 5 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP78257.1 - 3.4e-09 37.1 2.9 9.7e-09 35.6 2.9 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP78257.1 - 1.1e-07 31.4 38.0 1.6 9.5 0.1 10.7 10 1 1 11 11 11 5 Leucine Rich Repeat SPX PF03105.19 PRP78257.1 - 0.041 13.8 6.8 0.058 13.3 6.8 1.2 1 0 0 1 1 1 0 SPX domain MitoNEET_N PF10660.9 PRP78257.1 - 0.049 13.7 2.8 1.1e+02 2.9 0.0 5.7 6 0 0 6 6 6 0 Iron-containing outer mitochondrial membrane protein N-terminus Apt1 PF10351.9 PRP78257.1 - 0.12 11.2 13.8 0.19 10.5 13.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 PRP78257.1 - 0.88 9.5 28.2 1.6 8.7 28.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 PRP78257.1 - 2.3 6.7 19.1 3.5 6.1 19.1 1.2 1 0 0 1 1 1 0 Macoilin family Na_H_Exchanger PF00999.21 PRP78258.1 - 2e-55 188.2 41.3 2.5e-55 187.8 41.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SapB_2 PF03489.17 PRP78259.1 - 0.037 14.2 2.4 0.15 12.2 0.1 2.8 3 0 0 3 3 3 0 Saposin-like type B, region 2 Cupin_8 PF13621.6 PRP78260.1 - 1.1e-16 61.3 6.4 8e-16 58.5 0.5 3.2 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.22 PRP78260.1 - 1.8e-13 50.9 0.1 4.2e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 PRP78260.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP78260.1 - 0.0039 17.0 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.12 PRP78260.1 - 0.013 14.9 0.0 0.037 13.5 0.0 1.7 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_2 PF07883.11 PRP78260.1 - 0.022 14.5 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Cupin domain WEMBL PF05701.11 PRP78261.1 - 0.027 13.2 2.1 0.037 12.7 2.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.12 PRP78261.1 - 0.092 12.8 4.3 0.25 11.4 4.3 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HAD_2 PF13419.6 PRP78262.1 - 2.1e-20 73.6 0.0 3e-20 73.1 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP78262.1 - 7.6e-15 55.8 0.0 9.7e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP78262.1 - 9.5e-11 41.6 0.0 2.3e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like KH_1 PF00013.29 PRP78263.1 - 0.069 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 KH domain Mito_fiss_reg PF05308.11 PRP78264.1 - 0.037 14.1 0.4 0.037 14.1 0.4 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator AATF-Che1 PF13339.6 PRP78264.1 - 0.29 11.8 3.4 0.3 11.8 1.0 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor CLU PF13236.6 PRP78266.1 - 3.6e-59 200.3 0.0 6.8e-59 199.4 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria LRR_4 PF12799.7 PRP78266.1 - 2.4e-16 59.5 19.0 0.00064 20.1 0.3 9.4 8 2 4 12 12 12 7 Leucine Rich repeats (2 copies) UQ_con PF00179.26 PRP78266.1 - 1.7e-14 53.7 2.2 6.2e-14 51.8 0.0 2.9 3 1 0 3 3 3 1 Ubiquitin-conjugating enzyme eIF3_p135 PF12807.7 PRP78266.1 - 3.9e-07 30.3 0.1 1.1e-06 28.8 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 LRR_6 PF13516.6 PRP78266.1 - 8.2e-06 25.5 22.1 4.5 7.6 0.0 11.0 12 1 0 12 12 12 3 Leucine Rich repeat zf-CCCH PF00642.24 PRP78266.1 - 0.014 15.3 0.6 0.62 10.0 0.1 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_8 PF13855.6 PRP78266.1 - 0.06 13.1 22.5 0.21 11.4 0.2 5.9 5 1 0 5 5 5 0 Leucine rich repeat zf-RING_11 PF17123.5 PRP78266.1 - 1.2 8.9 3.8 17 5.2 0.3 3.3 3 0 0 3 3 3 0 RING-like zinc finger Coatomer_E PF04733.14 PRP78267.1 - 4e-05 23.2 0.1 5e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_14 PF13428.6 PRP78267.1 - 0.008 16.9 0.0 0.47 11.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP78267.1 - 0.015 15.3 0.1 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP78267.1 - 0.016 15.7 0.0 4 8.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP78267.1 - 0.04 13.6 0.2 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 TPR repeat ARGLU PF15346.6 PRP78267.1 - 0.044 13.7 2.9 0.053 13.4 1.2 1.8 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 HTH_29 PF13551.6 PRP78270.1 - 0.0032 17.5 0.0 0.0094 15.9 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 PRP78270.1 - 0.072 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.6 PRP78270.1 - 0.31 11.1 0.6 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 HTH domain FlgI PF02119.16 PRP78272.1 - 0.058 12.3 0.2 4.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Flagellar P-ring protein EPO_TPO PF00758.18 PRP78272.1 - 0.077 13.0 0.4 0.18 11.9 0.1 1.8 2 1 0 2 2 2 0 Erythropoietin/thrombopoietin G-patch_2 PF12656.7 PRP78273.1 - 6.4e-16 58.2 0.0 6.4e-16 58.2 0.0 2.5 3 0 0 3 3 3 1 G-patch domain KN17_SH3 PF18131.1 PRP78273.1 - 9e-10 38.5 0.0 4.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain G-patch PF01585.23 PRP78273.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 G-patch domain Acylphosphatase PF00708.18 PRP78273.1 - 0.025 15.0 0.4 2.6 8.5 0.2 2.6 2 0 0 2 2 2 0 Acylphosphatase KOW PF00467.29 PRP78273.1 - 0.032 14.2 0.1 0.032 14.2 0.1 3.0 3 0 0 3 3 3 0 KOW motif FXMRP1_C_core PF12235.8 PRP78273.1 - 2.8 8.6 8.1 6.6 7.4 7.5 1.9 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal Conotoxin PF02950.17 PRP78273.1 - 2.8 9.0 4.8 41 5.3 0.1 2.3 2 0 0 2 2 2 0 Conotoxin Pkinase_Tyr PF07714.17 PRP78274.1 - 1.6e-73 247.2 0.0 2.7e-73 246.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78274.1 - 9.5e-54 182.5 0.0 1.6e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Atg8 PF02991.16 PRP78274.1 - 1.1e-43 147.6 0.1 2.2e-43 146.7 0.1 1.5 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like LRR_8 PF13855.6 PRP78274.1 - 1.9e-41 139.6 96.0 1.2e-06 28.2 5.1 15.0 7 5 10 17 17 17 15 Leucine rich repeat LRR_4 PF12799.7 PRP78274.1 - 1.5e-35 120.6 89.9 0.00047 20.5 0.1 18.1 11 4 10 21 21 21 16 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP78274.1 - 2.4e-14 52.1 42.9 2.6 8.3 0.0 18.4 21 0 0 21 21 17 2 Leucine Rich repeat LRR_1 PF00560.33 PRP78274.1 - 6.7e-07 29.0 89.7 5.7 7.9 0.0 22.8 26 1 0 26 26 22 3 Leucine Rich Repeat APG12 PF04110.13 PRP78274.1 - 1.7e-05 25.1 0.1 5.8e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 Ubiquitin-like autophagy protein Apg12 Kinase-like PF14531.6 PRP78274.1 - 0.0047 16.3 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP78274.1 - 0.0053 15.6 0.1 0.011 14.5 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP78274.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP78274.1 - 0.0084 15.1 0.6 0.085 11.8 0.6 2.1 1 1 0 1 1 1 1 Haspin like kinase domain LRRNT_2 PF08263.12 PRP78274.1 - 0.028 14.7 1.0 0.088 13.1 1.0 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain DUF4381 PF14316.6 PRP78274.1 - 0.087 13.1 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SAM_3 PF18016.1 PRP78274.1 - 2.7 7.9 5.4 67 3.4 0.0 3.9 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) DoxX PF07681.12 PRP78275.1 - 0.17 12.5 4.3 0.54 10.9 0.6 2.6 2 1 1 3 3 3 0 DoxX YdjM PF04307.14 PRP78275.1 - 0.44 9.8 11.2 0.47 9.7 9.8 1.8 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Grg1 PF11034.8 PRP78276.1 - 4.4e-31 106.9 11.1 5.8e-31 106.5 11.1 1.2 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 EF-hand_1 PF00036.32 PRP78277.1 - 1.6e-13 49.1 0.0 0.00013 21.2 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PRP78277.1 - 1.2e-12 46.7 0.0 0.00014 21.5 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 PRP78277.1 - 3.1e-12 46.8 0.0 1.8e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP78277.1 - 2.3e-09 37.0 0.0 0.00046 20.0 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PRP78277.1 - 8.3e-08 31.4 0.0 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 PRP78277.1 - 0.004 17.4 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain bZIP_1 PF00170.21 PRP78278.1 - 1.5e-05 25.0 10.7 3.2e-05 23.9 10.7 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PRP78278.1 - 0.0028 17.7 10.0 0.0028 17.7 10.0 2.1 1 1 1 2 2 2 1 Basic region leucine zipper BRE1 PF08647.11 PRP78278.1 - 0.0033 17.5 9.6 0.0055 16.8 9.6 1.3 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.9 PRP78278.1 - 0.012 15.7 10.2 0.018 15.0 10.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Methyltransf_10 PF05971.12 PRP78278.1 - 0.028 13.8 0.2 0.04 13.3 0.2 1.2 1 0 0 1 1 1 0 RNA methyltransferase bZIP_Maf PF03131.17 PRP78278.1 - 0.099 13.2 7.7 0.23 12.0 7.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6_N PF17675.1 PRP78278.1 - 0.11 13.0 8.1 0.18 12.3 8.1 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5384 PF17358.2 PRP78278.1 - 0.33 11.0 8.4 0.55 10.3 8.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5384) DivIC PF04977.15 PRP78278.1 - 0.77 9.6 4.7 0.51 10.1 2.2 1.9 1 1 0 1 1 1 0 Septum formation initiator JIP_LZII PF16471.5 PRP78278.1 - 1.1 9.5 10.5 0.98 9.6 2.7 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Get5_C PF18514.1 PRP78280.1 - 0.01 15.5 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 Get5 C-terminal domain Homeodomain PF00046.29 PRP78282.1 - 7.4e-14 51.3 3.7 1.1e-13 50.8 3.7 1.3 1 0 0 1 1 1 1 Homeodomain Catalase-rel PF06628.12 PRP78282.1 - 0.0013 18.9 0.1 0.004 17.3 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Homeobox_KN PF05920.11 PRP78282.1 - 0.0092 15.9 0.8 0.017 15.0 0.8 1.5 1 0 0 1 1 1 1 Homeobox KN domain Codanin-1_C PF15296.6 PRP78282.1 - 0.031 14.4 0.2 0.031 14.4 0.2 2.1 1 1 1 2 2 2 0 Codanin-1 C-terminus Pkinase PF00069.25 PRP78283.1 - 8.4e-54 182.7 0.3 1.5e-53 181.8 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78283.1 - 1.7e-22 79.9 0.0 3.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Synaptobrevin PF00957.21 PRP78283.1 - 1e-12 47.7 2.2 1e-12 47.7 2.2 2.0 3 0 0 3 3 3 1 Synaptobrevin Kinase-like PF14531.6 PRP78283.1 - 0.004 16.5 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 PRP78283.1 - 0.0074 15.9 0.1 0.023 14.3 0.1 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase ANAPC4_WD40 PF12894.7 PRP78283.1 - 0.0083 16.4 0.0 23 5.4 0.0 4.2 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP78283.1 - 0.18 12.7 0.6 1.3 10.0 0.4 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat PSK_trans_fac PF07704.11 PRP78283.1 - 7.7 7.4 12.2 1.2 9.9 5.1 2.8 3 0 0 3 3 3 0 Rv0623-like transcription factor tRNA_U5-meth_tr PF05958.11 PRP78284.1 - 6e-14 51.8 0.2 2.2e-12 46.7 0.1 2.8 1 1 1 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 PRP78284.1 - 1.5e-11 44.3 0.1 3.4e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP78284.1 - 1.1e-09 38.9 0.0 3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP78284.1 - 3.9e-06 26.5 0.1 8.1e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 PRP78284.1 - 7e-06 25.6 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 PRP78284.1 - 1.1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 PRP78284.1 - 1.4e-05 24.7 0.1 3.8e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 PRP78284.1 - 3.5e-05 23.2 0.1 6.9e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 PRP78284.1 - 4.9e-05 22.9 0.2 0.00013 21.5 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 PRP78284.1 - 0.00022 21.0 0.1 0.00045 20.0 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 PRP78284.1 - 0.00033 20.5 0.0 0.001 19.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP78284.1 - 0.00067 20.3 0.0 0.0019 18.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 PRP78284.1 - 0.0013 18.6 0.0 0.003 17.3 0.0 1.6 2 0 0 2 2 1 1 Met-10+ like-protein NodS PF05401.11 PRP78284.1 - 0.0083 15.8 0.2 0.029 14.0 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 PRP78284.1 - 0.011 15.8 0.1 0.011 15.8 0.1 2.5 3 2 0 3 3 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 PRP78284.1 - 0.011 16.4 0.0 0.033 14.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain N6_N4_Mtase PF01555.18 PRP78284.1 - 0.013 15.3 0.0 0.039 13.7 0.0 2.0 2 1 0 2 2 2 0 DNA methylase Methyltransf_18 PF12847.7 PRP78284.1 - 0.02 14.8 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.16 PRP78284.1 - 0.031 13.4 0.0 0.073 12.2 0.0 1.6 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase GATase_2 PF00310.21 PRP78286.1 - 2.3e-173 576.7 0.0 3e-173 576.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 PRP78286.1 - 3.2e-107 358.9 1.0 5.9e-107 358.0 1.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 PRP78286.1 - 1.4e-101 339.6 0.0 2.3e-101 339.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GATase_6 PF13522.6 PRP78286.1 - 0.017 15.3 0.0 0.058 13.6 0.0 1.9 1 0 0 1 1 1 0 Glutamine amidotransferase domain PPR_long PF17177.4 PRP78287.1 - 0.07 12.5 0.0 8.7 5.6 0.0 3.1 2 2 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP ESCRT-II PF05871.12 PRP78288.1 - 2e-43 148.0 0.0 2.8e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit MMR_HSR1 PF01926.23 PRP78289.1 - 7.8e-17 61.4 0.1 7.5e-15 55.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP78289.1 - 2.9e-08 33.8 0.6 1.9e-05 24.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 PRP78289.1 - 9.5e-07 28.5 0.3 2.3e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PRP78289.1 - 0.00015 21.4 0.5 0.48 9.9 0.1 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain TniB PF05621.11 PRP78289.1 - 0.011 15.2 0.1 0.021 14.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF2031 PF09592.10 PRP78289.1 - 0.014 14.9 0.7 0.022 14.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Arf PF00025.21 PRP78289.1 - 0.021 14.3 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 PRP78289.1 - 0.029 14.9 0.0 0.084 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 PRP78289.1 - 0.08 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Roc PF08477.13 PRP78289.1 - 0.081 13.1 0.1 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF1175 PF06672.11 PRP78289.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) AAA_16 PF13191.6 PRP78289.1 - 0.13 12.7 0.0 2.7 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain PI3K_P85_iSH2 PF16454.5 PRP78290.1 - 0.014 15.0 1.5 0.018 14.7 1.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain BshC PF10079.9 PRP78290.1 - 0.017 13.9 0.9 0.019 13.7 0.9 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF2205 PF10224.9 PRP78290.1 - 0.17 11.9 2.3 0.38 10.8 0.5 2.0 1 1 1 2 2 2 0 Short coiled-coil protein IZUMO PF15005.6 PRP78290.1 - 0.18 12.3 0.9 0.26 11.8 0.9 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated TPR_MLP1_2 PF07926.12 PRP78290.1 - 0.4 10.7 4.5 0.43 10.6 0.8 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein D123 PF07065.14 PRP78291.1 - 1.2e-25 90.3 1.1 1.6e-22 80.0 0.2 2.9 2 1 0 3 3 3 2 D123 R2K_2 PF18299.1 PRP78291.1 - 5.7e-07 29.5 0.0 1.6e-06 28.1 0.0 1.7 1 1 1 2 2 2 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 PRP78291.1 - 0.002 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 Nepo_coat_N PF03689.15 PRP78291.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain RNase_T PF00929.24 PRP78292.1 - 1.3e-21 77.8 0.1 1.3e-20 74.6 0.1 2.1 1 1 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 PRP78292.1 - 9e-09 35.5 0.0 2.6e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DNA_pol_A_exo1 PF01612.20 PRP78292.1 - 0.023 14.4 0.1 0.11 12.1 0.0 2.2 2 1 0 2 2 2 0 3'-5' exonuclease RNase_H_2 PF13482.6 PRP78292.1 - 0.032 14.2 0.1 2.6 8.0 0.0 2.5 2 0 0 2 2 2 0 RNase_H superfamily GMC_oxred_N PF00732.19 PRP78293.1 - 9.8e-32 110.5 0.0 2.6e-31 109.1 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP78293.1 - 2.4e-13 50.8 0.0 4.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PRP78293.1 - 1.1e-05 25.5 0.0 2.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PRP78293.1 - 0.0012 18.1 0.0 0.0035 16.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 PRP78293.1 - 0.0012 18.5 0.0 0.016 14.8 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP78293.1 - 0.002 17.4 0.0 0.044 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP78293.1 - 0.0095 14.7 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 PRP78293.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 PRP78293.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 PRP78293.1 - 0.18 11.0 0.1 1.4 8.2 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lipoprotein_7 PF01540.16 PRP78294.1 - 0.0013 18.1 14.0 0.0013 18.1 14.0 4.2 1 1 3 4 4 4 1 Adhesin lipoprotein ATG16 PF08614.11 PRP78294.1 - 0.0031 17.8 13.2 0.0031 17.8 13.2 8.5 2 2 5 7 7 7 4 Autophagy protein 16 (ATG16) DUF3113 PF11310.8 PRP78294.1 - 0.074 13.0 0.6 19 5.3 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) FAM25 PF15825.5 PRP78294.1 - 0.7 10.3 5.6 3.1 8.2 0.1 3.6 3 0 0 3 3 3 0 FAM25 family TYW3 PF02676.14 PRP78295.1 - 7.7e-39 133.3 0.0 1.1e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 FWWh PF14922.6 PRP78296.1 - 4.6e-14 52.6 1.4 9.3e-14 51.6 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function ACP_PD PF04336.12 PRP78296.1 - 0.097 13.1 0.6 0.34 11.3 0.6 1.9 1 0 0 1 1 1 0 Acyl carrier protein phosphodiesterase DUF4407 PF14362.6 PRP78296.1 - 0.12 11.7 0.2 0.2 10.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FH2 PF02181.23 PRP78297.1 - 7.8e-81 272.1 7.6 7.8e-81 272.1 7.6 4.2 4 1 1 5 5 5 2 Formin Homology 2 Domain EAP30 PF04157.16 PRP78298.1 - 2.4e-36 125.2 0.3 3.4e-36 124.7 0.3 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 PRP78298.1 - 1.3e-14 54.1 0.0 2.5e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 BBL5 PF07289.11 PRP78298.1 - 0.00039 19.6 0.1 0.00081 18.5 0.0 1.4 1 1 0 1 1 1 1 Bardet-Biedl syndrome 5 protein PH_TFIIH PF08567.11 PRP78298.1 - 0.0017 18.7 0.0 0.0061 16.9 0.0 1.9 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Lsr2 PF11774.8 PRP78298.1 - 0.065 13.4 0.3 0.19 11.9 0.1 1.9 1 1 0 1 1 1 0 Lsr2 DRTGG PF07085.12 PRP78298.1 - 0.11 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 DRTGG domain RNase_T PF00929.24 PRP78299.1 - 8.8e-08 32.9 1.2 8.8e-08 32.9 1.2 3.7 3 1 0 3 3 3 1 Exonuclease AT_hook PF02178.19 PRP78299.1 - 0.013 15.3 2.2 0.033 14.0 2.2 1.7 1 0 0 1 1 1 0 AT hook motif Zip PF02535.22 PRP78299.1 - 0.23 10.7 0.7 0.38 9.9 0.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Inp1 PF12634.7 PRP78299.1 - 0.25 11.3 2.2 0.83 9.7 0.4 2.3 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 AP3D1 PF06375.11 PRP78299.1 - 0.44 10.8 8.5 0.16 12.2 5.6 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Sec62 PF03839.16 PRP78299.1 - 3.4 7.1 7.5 5.7 6.4 7.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Dicty_REP PF05086.12 PRP78299.1 - 4.5 5.1 9.3 0.25 9.3 3.9 1.5 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein FAD_binding_3 PF01494.19 PRP78300.1 - 8.3e-22 77.9 0.3 2.2e-16 60.1 0.0 2.6 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 PRP78300.1 - 3.8e-07 29.6 0.2 0.0022 17.3 0.1 2.6 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP78300.1 - 1.6e-05 25.0 0.1 3.9e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP78300.1 - 0.00019 21.1 0.4 0.00073 19.2 0.4 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PRP78300.1 - 0.00024 20.3 0.0 0.054 12.5 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 PRP78300.1 - 0.00043 20.8 0.3 0.79 10.3 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP78300.1 - 0.0015 17.7 0.2 0.0021 17.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 PRP78300.1 - 0.0089 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PRP78300.1 - 0.012 14.8 0.0 0.1 11.9 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PRP78300.1 - 0.017 14.8 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.10 PRP78300.1 - 0.022 13.8 0.0 0.041 12.9 0.0 1.3 1 1 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 PRP78300.1 - 0.065 11.9 0.1 0.21 10.2 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 PRP78300.1 - 0.13 11.5 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pmp3 PF01679.17 PRP78301.1 - 7.1e-14 51.7 13.6 8.5e-14 51.5 13.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.11 PRP78301.1 - 0.22 11.9 5.7 0.4 11.0 4.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1056) HRG PF16954.5 PRP78302.1 - 0.013 15.9 14.2 0.2 12.1 4.4 3.4 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Prominin PF05478.11 PRP78302.1 - 1.2 7.0 3.1 1.2 7.0 3.1 1.2 1 0 0 1 1 1 0 Prominin LRR_8 PF13855.6 PRP78303.1 - 2.5e-60 200.1 114.6 5.9e-08 32.4 0.1 15.8 9 4 4 16 16 16 15 Leucine rich repeat LRR_4 PF12799.7 PRP78303.1 - 3.8e-36 122.5 136.9 6.2e-06 26.5 3.5 19.9 10 4 10 22 22 22 17 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP78303.1 - 7.7e-08 31.9 101.9 0.22 12.2 0.1 24.3 25 4 0 25 25 25 9 Leucine Rich Repeat DUF899 PF05988.12 PRP78304.1 - 0.016 14.7 0.1 0.019 14.5 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) zf-C2H2_9 PF16293.5 PRP78304.1 - 0.043 13.7 0.1 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) His_Phos_1 PF00300.22 PRP78305.1 - 1.7e-22 80.0 0.1 2.4e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 PRP78305.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 PRP78306.1 - 1.5e-48 165.5 0.0 2.1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78306.1 - 2.2e-30 105.8 0.0 3.6e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP78306.1 - 7.8e-07 28.2 0.0 1.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP78306.1 - 2e-06 27.3 0.2 3.9e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP78306.1 - 9.6e-06 25.7 0.7 0.0015 18.5 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 PRP78306.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP78306.1 - 0.074 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1981 PF09324.10 PRP78307.1 - 1.3e-34 117.9 11.3 2.7e-34 116.9 0.3 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Mon2_C PF16206.5 PRP78307.1 - 0.00058 18.2 0.0 0.0022 16.3 0.0 1.9 2 0 0 2 2 2 1 C-terminal region of Mon2 protein Glyco_tran_WbsX PF14307.6 PRP78307.1 - 0.025 14.0 0.1 0.077 12.4 0.1 1.8 1 0 0 1 1 1 0 Glycosyltransferase WbsX MRNIP PF15749.5 PRP78307.1 - 6.1 7.6 8.8 0.66 10.7 2.5 2.5 2 0 0 2 2 2 0 MRN-interacting protein Pkinase_Tyr PF07714.17 PRP78308.1 - 1.8e-71 240.5 0.0 2.7e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78308.1 - 2.1e-49 168.3 0.0 2.9e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP78308.1 - 6.1e-48 160.4 107.3 3.3e-10 39.6 5.0 17.3 15 3 3 18 18 18 14 Leucine rich repeat LRR_4 PF12799.7 PRP78308.1 - 3.7e-40 135.3 116.5 0.00046 20.5 0.2 19.8 15 4 4 20 20 20 14 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP78308.1 - 4.7e-07 29.3 82.8 2 8.7 0.0 20.8 25 0 0 25 25 24 6 Leucine Rich repeat LRR_5 PF13306.6 PRP78308.1 - 0.015 15.2 8.0 5.4 7.0 0.2 5.0 5 0 0 5 5 5 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PRP78308.1 - 0.037 14.5 113.1 0.44 11.3 0.1 25.3 26 6 1 27 27 21 0 Leucine Rich Repeat LRR_9 PF14580.6 PRP78308.1 - 0.092 12.2 21.0 0.31 10.5 1.6 6.1 5 3 2 7 7 7 0 Leucine-rich repeat DUF4690 PF15756.5 PRP78308.1 - 0.15 12.7 2.4 0.34 11.5 2.4 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Kdo PF06293.14 PRP78308.1 - 0.23 10.8 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VSP PF03302.13 PRP78308.1 - 0.51 9.1 1.2 0.73 8.6 1.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Suppressor_P21 PF11479.8 PRP78308.1 - 1 9.6 8.1 2.9 8.2 0.1 3.9 4 0 0 4 4 4 0 RNA silencing suppressor P21 C-terminal domain Ank_2 PF12796.7 PRP78310.1 - 3.1e-08 34.1 3.2 0.00081 19.9 0.3 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP78310.1 - 0.0014 18.9 2.9 45 5.1 0.0 5.4 5 1 1 6 6 6 0 Ankyrin repeat Ank_4 PF13637.6 PRP78310.1 - 0.0026 18.3 2.2 12 6.6 0.1 3.9 1 1 3 4 4 4 2 Ankyrin repeats (many copies) DUF3644 PF12358.8 PRP78310.1 - 0.017 15.6 0.2 0.052 14.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) Ank PF00023.30 PRP78310.1 - 0.3 11.6 6.9 95 3.7 0.0 4.9 5 1 0 5 5 5 0 Ankyrin repeat HA PF03457.14 PRP78311.1 - 3.1e-06 27.4 3.5 3.1e-06 27.4 3.5 2.6 3 2 0 3 3 3 1 Helicase associated domain TspO_MBR PF03073.15 PRP78313.1 - 1.6e-17 63.8 8.2 1.6e-17 63.8 8.2 3.2 2 1 1 3 3 3 1 TspO/MBR family LAP1C PF05609.12 PRP78313.1 - 0.11 11.6 3.8 0.15 11.2 3.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TMEM215 PF15746.5 PRP78313.1 - 0.2 11.1 0.3 0.32 10.4 0.3 1.2 1 0 0 1 1 1 0 TMEM215 family AP3D1 PF06375.11 PRP78313.1 - 0.62 10.3 8.9 0.91 9.7 8.9 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_A21 PF03566.13 PRP78313.1 - 2.8 6.1 5.0 4.1 5.6 5.0 1.1 1 0 0 1 1 1 0 Peptidase family A21 Cystatin PF00031.21 PRP78314.1 - 3.6e-11 43.2 0.9 5.3e-11 42.6 0.1 1.6 2 0 0 2 2 2 1 Cystatin domain Dynein_light PF01221.18 PRP78314.1 - 0.049 13.9 0.2 0.066 13.5 0.2 1.4 1 1 0 1 1 1 0 Dynein light chain type 1 DUF1724 PF08350.10 PRP78315.1 - 0.075 13.2 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) HEAT_2 PF13646.6 PRP78317.1 - 0.00022 21.5 0.2 0.22 12.0 0.0 3.9 3 0 0 3 3 3 1 HEAT repeats ARS2 PF04959.13 PRP78318.1 - 4.5e-12 46.8 0.6 4.5e-12 46.8 0.6 1.8 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 PRP78318.1 - 1.7e-10 41.1 6.1 1.7e-10 41.1 6.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 PRP78318.1 - 4.8e-08 32.7 1.7 1.3e-07 31.2 1.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) TraP PF07296.11 PRP78318.1 - 0.21 10.7 0.3 0.77 8.9 0.1 2.0 2 0 0 2 2 2 0 TraP protein zf-C2H2_4 PF13894.6 PRP78318.1 - 0.35 11.8 4.3 2.6 9.1 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger UbiA PF01040.18 PRP78318.1 - 0.51 9.6 3.5 0.89 8.8 3.5 1.3 1 0 0 1 1 1 0 UbiA prenyltransferase family THOC7 PF05615.13 PRP78320.1 - 3.9e-10 40.1 8.3 3.9e-10 40.1 8.3 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 TRAF_BIRC3_bd PF16673.5 PRP78320.1 - 0.0037 17.0 0.8 0.0037 17.0 0.8 2.8 2 1 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain DUF4200 PF13863.6 PRP78320.1 - 0.014 15.8 6.6 0.014 15.8 6.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) IpgD PF05925.12 PRP78320.1 - 0.06 11.9 0.9 0.064 11.8 0.9 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD FUSC PF04632.12 PRP78320.1 - 0.2 10.1 0.7 0.24 9.9 0.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 PRP78320.1 - 2.7 7.5 8.5 3.4 7.2 8.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 PRP78320.1 - 4.8 7.0 14.4 15 5.4 13.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ERCC4 PF02732.15 PRP78321.1 - 7.2e-23 81.5 0.1 2.8e-22 79.6 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain HHH_8 PF14716.6 PRP78321.1 - 5.7e-11 42.6 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain SAM_1 PF00536.30 PRP78321.1 - 6.2e-07 29.8 0.1 2.8e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP78321.1 - 3.5e-06 27.0 0.0 1.3e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SNF2_N PF00176.23 PRP78323.1 - 1.4e-59 201.6 3.7 8.7e-59 199.0 3.7 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP78323.1 - 1.3e-17 64.1 0.0 8.3e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78323.1 - 2.8e-09 37.2 0.4 1e-08 35.4 0.1 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 PRP78323.1 - 7.8e-07 28.9 5.6 1.4e-06 28.1 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 PRP78323.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 PRP78323.1 - 4.8e-05 23.6 7.7 8.5e-05 22.8 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP78323.1 - 5.3e-05 23.0 5.3 0.00011 22.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP78323.1 - 5.6e-05 23.0 5.7 9.9e-05 22.2 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain SWI2_SNF2 PF18766.1 PRP78323.1 - 0.00047 19.9 0.2 0.00085 19.0 0.2 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-C3HC4_3 PF13920.6 PRP78323.1 - 0.00058 19.7 6.1 0.001 18.9 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP78323.1 - 0.001 19.0 3.5 0.0021 18.0 3.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PRP78323.1 - 0.0084 16.2 5.2 0.022 14.9 5.2 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PRP78323.1 - 0.023 14.5 5.4 0.047 13.6 5.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 PRP78323.1 - 0.099 12.5 0.7 0.3 10.9 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 PRP78323.1 - 0.17 12.2 6.2 0.37 11.1 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 PRP78323.1 - 0.86 9.5 7.5 1.7 8.5 7.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 PRP78323.1 - 0.9 9.2 7.5 1.7 8.3 7.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type UPF0515 PF15135.6 PRP78323.1 - 4.6 6.5 7.7 2.1 7.6 0.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 zf-MIZ PF02891.20 PRP78323.1 - 6.5 6.6 6.1 16 5.3 6.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Ufd2P_core PF10408.9 PRP78324.1 - 2.6e-45 155.2 3.1 4e-45 154.6 3.1 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core SpoIIIAH PF12685.7 PRP78324.1 - 0.065 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein FliD_C PF07195.12 PRP78324.1 - 0.086 12.2 1.0 14 5.0 0.4 2.8 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Imm40 PF15569.6 PRP78325.1 - 0.082 13.0 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 40 Peptidase_M14 PF00246.24 PRP78327.1 - 3.3e-66 224.0 0.4 4.7e-66 223.5 0.4 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase TMEM144 PF07857.12 PRP78327.1 - 3.1e-21 75.7 15.3 3.1e-21 75.7 15.3 1.5 2 0 0 2 2 2 1 Transmembrane family, TMEM144 of transporters CarboxypepD_reg PF13620.6 PRP78327.1 - 2.5e-09 37.3 0.8 5.1e-09 36.3 0.8 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Sugar_transport PF06800.12 PRP78327.1 - 3.6e-08 33.1 19.5 1.6e-06 27.7 8.5 2.4 2 0 0 2 2 2 2 Sugar transport protein AstE_AspA PF04952.14 PRP78327.1 - 1e-05 24.8 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 PRP78327.1 - 0.00046 19.7 0.2 0.00092 18.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) PEGA PF08308.11 PRP78327.1 - 0.0043 16.9 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 PEGA domain CarbopepD_reg_2 PF13715.6 PRP78327.1 - 0.041 13.9 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 CarboxypepD_reg-like domain UPF0060 PF02694.15 PRP78327.1 - 2.1 8.6 18.7 0.05 13.8 9.2 3.1 3 1 1 4 4 4 0 Uncharacterised BCR, YnfA/UPF0060 family DnaJ_C PF01556.18 PRP78328.1 - 5.1e-43 146.7 0.7 8.7e-43 146.0 0.7 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PRP78328.1 - 8.8e-26 89.8 4.7 1.7e-25 88.9 4.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PRP78328.1 - 1.5e-15 57.3 22.1 1.5e-15 57.3 22.1 2.0 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 PRP78328.1 - 7.9e-05 22.5 12.5 0.00063 19.6 1.6 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 PRP78328.1 - 0.00043 20.3 9.0 0.038 14.0 2.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Gp-FAR-1 PF05823.12 PRP78328.1 - 0.0055 17.1 0.5 0.012 16.0 0.5 1.5 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4770 PF15994.5 PRP78328.1 - 0.037 14.3 2.0 0.084 13.1 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) zinc_ribbon_6 PF14599.6 PRP78328.1 - 0.71 9.9 7.9 4.6 7.3 0.8 2.8 2 0 0 2 2 2 0 Zinc-ribbon zf-RING_10 PF16685.5 PRP78328.1 - 1.3 9.2 11.0 0.12 12.5 1.4 2.5 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 PRP78328.1 - 4.8 7.2 12.5 2.7 8.0 3.8 2.6 2 0 0 2 2 2 0 zinc-RING finger domain FSIP1 PF15554.6 PRP78329.1 - 0.013 14.6 0.1 0.013 14.6 0.1 1.1 1 0 0 1 1 1 0 FSIP1 family Mito_fiss_reg PF05308.11 PRP78331.1 - 0.0092 16.1 2.9 0.0092 16.1 2.9 2.3 2 0 0 2 2 2 1 Mitochondrial fission regulator CompInhib_SCIN PF11546.8 PRP78331.1 - 0.13 12.3 4.3 3.9 7.6 0.0 3.5 4 0 0 4 4 4 0 Staphylococcal complement inhibitor SCIN NPV_P10 PF05531.12 PRP78331.1 - 4.1 7.9 12.4 0.46 11.0 0.4 3.5 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein CDC37_N PF03234.14 PRP78331.1 - 7.1 7.6 13.3 7.3 7.5 9.4 2.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Pkinase_Tyr PF07714.17 PRP78332.1 - 1.1e-22 80.6 0.1 1.6e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP78332.1 - 8.1e-21 73.8 65.7 0.00011 22.4 1.7 11.7 7 4 4 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP78332.1 - 5e-18 64.6 54.9 9.4e-06 25.3 4.7 8.0 6 2 0 6 6 6 6 Leucine rich repeat Pkinase PF00069.25 PRP78332.1 - 7.4e-16 58.3 0.1 1.3e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP78332.1 - 1.1e-09 38.7 4.6 1.1e-09 38.7 4.6 2.1 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP78332.1 - 0.0094 16.4 54.6 4.7 8.2 0.1 14.7 14 2 1 15 15 15 3 Leucine Rich Repeat TMEM154 PF15102.6 PRP78332.1 - 0.24 11.3 2.7 0.23 11.3 0.2 2.1 2 0 0 2 2 2 0 TMEM154 protein family LRR_6 PF13516.6 PRP78332.1 - 0.48 10.6 0.0 0.48 10.6 0.0 12.7 15 1 1 16 16 16 0 Leucine Rich repeat SH3_1 PF00018.28 PRP78333.1 - 9.2e-12 44.4 0.0 2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP78333.1 - 1e-11 44.5 0.2 1.8e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP78333.1 - 3.5e-08 33.0 0.0 6.6e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain IMD PF08397.11 PRP78333.1 - 0.00013 21.4 1.7 0.00018 21.0 1.7 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain SF-assemblin PF06705.11 PRP78333.1 - 0.0033 16.8 3.7 0.0068 15.8 3.7 1.6 1 1 0 1 1 1 1 SF-assemblin/beta giardin DUF2205 PF10224.9 PRP78333.1 - 0.027 14.4 1.2 0.067 13.2 1.2 1.6 1 0 0 1 1 1 0 Short coiled-coil protein Mt_ATP-synt_D PF05873.12 PRP78333.1 - 0.3 10.9 2.9 0.66 9.8 1.4 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) PAP2 PF01569.21 PRP78334.1 - 1.9e-12 47.1 7.7 1.9e-12 47.1 7.7 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 PRP78334.1 - 0.082 12.6 11.0 0.62 9.7 11.0 2.1 1 1 0 1 1 1 0 PAP2 superfamily Trep_dent_lipo PF09710.10 PRP78336.1 - 6.7 5.5 14.7 2.8 6.8 3.3 2.2 2 0 0 2 2 2 0 Treponema clustered lipoprotein (Trep_dent_lipo) WD40 PF00400.32 PRP78337.1 - 1.3e-08 35.4 17.7 0.0017 19.1 0.2 5.6 4 1 0 4 4 4 3 WD domain, G-beta repeat Reg_prop PF07494.11 PRP78337.1 - 0.0013 18.7 1.2 19 5.9 0.0 4.3 4 0 0 4 4 4 2 Two component regulator propeller ANAPC4_WD40 PF12894.7 PRP78337.1 - 0.0029 17.9 0.5 0.4 11.0 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain adh_short PF00106.25 PRP78338.1 - 1.3e-39 135.7 0.0 2.5e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP78338.1 - 8.2e-28 97.5 0.0 1.4e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP78338.1 - 4e-07 30.1 0.0 6.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PRP78338.1 - 7.3e-05 22.3 0.0 0.00026 20.5 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) HEM4 PF02602.15 PRP78338.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Eno-Rase_NADH_b PF12242.8 PRP78338.1 - 0.19 11.5 1.3 0.72 9.7 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Gaa1 PF04114.14 PRP78339.1 - 3.1e-86 290.4 4.7 5.1e-86 289.7 4.7 1.4 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Sacchrp_dh_NADP PF03435.18 PRP78340.1 - 3.1e-14 53.3 0.1 7.3e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ASH PF15780.5 PRP78340.1 - 0.00011 22.4 1.5 0.00011 22.4 1.5 2.0 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin THOC7 PF05615.13 PRP78340.1 - 0.00014 22.1 3.4 0.00032 21.0 3.4 1.5 1 0 0 1 1 1 1 Tho complex subunit 7 SH2 PF00017.24 PRP78340.1 - 0.00028 20.9 0.0 0.00083 19.4 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Shikimate_DH PF01488.20 PRP78340.1 - 0.14 12.2 0.1 0.85 9.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ABC_tran_CTD PF16326.5 PRP78340.1 - 6.8 7.0 7.1 1.8 8.9 3.9 1.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Pex16 PF08610.10 PRP78341.1 - 8.9e-51 173.0 1.5 1.1e-50 172.7 1.5 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) CH PF00307.31 PRP78342.1 - 3.3e-66 220.3 1.5 9.4e-20 70.8 0.1 4.5 4 0 0 4 4 4 4 Calponin homology (CH) domain WD40 PF00400.32 PRP78342.1 - 8.8e-15 54.9 10.2 0.086 13.7 0.2 6.7 6 1 0 6 6 6 4 WD domain, G-beta repeat CAMSAP_CH PF11971.8 PRP78342.1 - 3e-09 36.6 0.5 0.0025 17.6 0.0 3.9 4 0 0 4 4 4 2 CAMSAP CH domain RPEL PF02755.15 PRP78342.1 - 1.8e-06 27.4 3.5 2.1e-05 24.0 0.3 2.8 2 0 0 2 2 2 1 RPEL repeat CH_2 PF06294.11 PRP78342.1 - 0.0026 17.8 0.2 0.01 15.9 0.0 2.2 2 0 0 2 2 2 1 CH-like domain in sperm protein ANAPC4_WD40 PF12894.7 PRP78342.1 - 0.043 14.1 0.9 13 6.1 0.0 3.8 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 PRP78342.1 - 0.058 12.4 2.2 0.67 8.9 1.1 2.8 2 1 0 2 2 2 0 Coatomer WD associated region CPSF100_C PF13299.6 PRP78342.1 - 0.65 10.2 11.4 0.096 12.9 4.8 2.8 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal G0-G1_switch_2 PF15103.6 PRP78342.1 - 2.6 8.5 9.0 0.53 10.7 4.6 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF809 PF05663.11 PRP78342.1 - 3 8.0 18.2 11 6.2 18.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF1682 PF07946.14 PRP78342.1 - 4.2 6.5 15.8 8.8 5.4 15.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RNA_pol_Rpc4 PF05132.14 PRP78342.1 - 4.5 7.7 12.9 3 8.2 6.8 3.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 PRP78342.1 - 4.5 5.9 7.5 7.8 5.1 7.5 1.3 1 0 0 1 1 1 0 Presenilin Thg1 PF04446.12 PRP78343.1 - 6.9e-48 161.8 0.9 8.3e-48 161.5 0.3 1.4 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.6 PRP78343.1 - 9.5e-41 138.8 1.8 9.5e-41 138.8 1.8 1.7 2 1 0 2 2 2 1 Thg1 C terminal domain DUF218 PF02698.17 PRP78344.1 - 0.0043 17.1 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain PAS_9 PF13426.7 PRP78345.1 - 3.1e-12 46.6 0.0 8.8e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 PRP78345.1 - 1e-08 35.2 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 PRP78345.1 - 1.3e-08 35.6 0.0 3.3e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 PRP78345.1 - 8.9e-05 22.8 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain PAS_8 PF13188.7 PRP78345.1 - 0.0087 16.1 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_7 PF12860.7 PRP78345.1 - 0.091 12.9 0.2 0.21 11.8 0.2 1.6 1 0 0 1 1 1 0 PAS fold Aldo_ket_red PF00248.21 PRP78346.1 - 1.9e-47 161.9 0.0 4.5e-45 154.1 0.0 3.1 2 1 0 2 2 2 1 Aldo/keto reductase family HATPase_c PF02518.26 PRP78346.1 - 1.2e-27 96.6 0.2 2.5e-27 95.6 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP78346.1 - 2.1e-22 79.4 0.9 5.3e-22 78.1 0.9 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 PRP78346.1 - 1.6e-13 50.5 0.7 4.9e-13 48.9 0.1 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 PRP78346.1 - 6.9e-11 42.3 0.0 2.4e-10 40.6 0.0 2.1 1 0 0 1 1 1 1 PAS domain GAF PF01590.26 PRP78346.1 - 1.4e-07 32.2 0.3 4.8e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 PRP78346.1 - 3.9e-06 26.7 0.0 8.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 PRP78346.1 - 9.9e-06 25.5 0.1 8.6e-05 22.5 0.0 2.7 3 1 0 3 3 3 1 PAS fold PAS_3 PF08447.12 PRP78346.1 - 0.00068 19.9 0.1 0.0026 18.0 0.1 2.1 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 PRP78346.1 - 0.029 14.4 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 PAS domain Methyltransf_19 PF04672.12 PRP78346.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl methyltransferase CH_2 PF06294.11 PRP78347.1 - 2.5e-30 104.4 0.0 5.4e-30 103.4 0.0 1.6 1 1 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PRP78347.1 - 5.8e-13 48.5 0.0 1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain HOOK PF05622.12 PRP78347.1 - 0.027 12.6 0.0 0.034 12.3 0.0 1.1 1 0 0 1 1 1 0 HOOK protein CH PF00307.31 PRP78347.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain DIOX_N PF14226.6 PRP78348.1 - 1.5e-10 41.9 0.0 6.4e-10 39.8 0.0 2.1 3 0 0 3 3 3 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PRP78348.1 - 0.0079 16.7 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TetR_N PF00440.23 PRP78348.1 - 0.097 12.5 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family DNA_pol_B_palm PF14792.6 PRP78349.1 - 8.6e-31 106.5 0.3 3.6e-30 104.5 0.2 2.3 2 0 0 2 2 1 1 DNA polymerase beta palm AAA_12 PF13087.6 PRP78349.1 - 4e-25 88.6 0.0 1e-24 87.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PRP78349.1 - 1.2e-24 87.5 0.0 5.5e-21 75.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain HHH_8 PF14716.6 PRP78349.1 - 1.6e-15 57.2 1.2 2.2e-12 47.2 0.6 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.6 PRP78349.1 - 5.1e-13 49.0 0.0 8.8e-12 45.0 0.0 3.3 3 0 0 3 3 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 PRP78349.1 - 2.7e-12 46.3 0.0 7.6e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda AAA_19 PF13245.6 PRP78349.1 - 5.6e-08 33.2 0.0 2e-06 28.2 0.0 2.9 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 PRP78349.1 - 0.00023 20.8 5.4 0.02 14.5 0.0 3.0 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 PRP78349.1 - 0.0011 18.7 0.0 0.081 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 PRP78349.1 - 0.0026 17.1 0.0 0.0026 17.1 0.0 2.0 2 0 0 2 2 1 1 Uncharacterized conserved protein (DUF2075) HHH_5 PF14520.6 PRP78349.1 - 0.0037 17.8 0.2 0.096 13.3 0.3 2.6 1 1 1 2 2 2 2 Helix-hairpin-helix domain Pox_Ag35 PF03286.14 PRP78349.1 - 0.015 15.1 6.0 0.039 13.7 6.0 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FHA_2 PF17913.1 PRP78349.1 - 0.033 14.4 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 FHA domain NTP_transf_2 PF01909.23 PRP78349.1 - 0.051 13.9 0.0 0.051 13.9 0.0 2.9 3 0 0 3 3 1 0 Nucleotidyltransferase domain HHH_3 PF12836.7 PRP78349.1 - 0.067 13.5 0.2 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif AAA_25 PF13481.6 PRP78349.1 - 0.081 12.5 0.1 2.4 7.7 0.0 3.0 3 0 0 3 3 3 0 AAA domain APC1_C PF18122.1 PRP78349.1 - 0.11 12.4 0.2 11 5.9 0.2 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain AAA PF00004.29 PRP78349.1 - 0.11 12.9 0.4 2 8.8 0.4 2.8 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) CLN3 PF02487.17 PRP78349.1 - 0.13 11.3 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 CLN3 protein PPL5 PF18168.1 PRP78349.1 - 0.4 9.9 4.0 0.98 8.7 4.0 1.6 1 0 0 1 1 1 0 Prim-pol family 5 AAA_16 PF13191.6 PRP78349.1 - 1.6 9.1 3.9 2.4 8.5 0.0 3.0 2 1 0 3 3 2 0 AAA ATPase domain Connexin PF00029.19 PRP78349.1 - 1.7 8.4 5.4 4.1 7.1 5.4 1.6 1 0 0 1 1 1 0 Connexin RPN2_C PF18004.1 PRP78349.1 - 3 7.8 13.5 8.6 6.2 13.5 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Tim54 PF11711.8 PRP78349.1 - 7.6 5.2 13.5 38 2.9 12.4 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FYDLN_acid PF09538.10 PRP78349.1 - 8.6 7.1 13.4 22 5.8 8.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) FH2 PF02181.23 PRP78350.1 - 1.6e-65 221.7 5.4 1.6e-65 221.7 5.4 3.0 2 1 1 3 3 3 1 Formin Homology 2 Domain Sulfatase PF00884.23 PRP78350.1 - 2e-44 152.3 0.0 3.3e-44 151.5 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Bromodomain PF00439.25 PRP78350.1 - 1.3e-22 79.6 0.2 4.6e-22 77.9 0.1 2.1 2 0 0 2 2 2 1 Bromodomain Choline_sulf_C PF12411.8 PRP78350.1 - 7.9e-22 76.8 0.2 1.9e-21 75.6 0.2 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 PRP78350.1 - 1.1e-07 31.8 3.7 1.4e-07 31.5 0.1 2.8 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 PRP78350.1 - 3.4e-07 30.5 0.0 3.4e-07 30.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 PRP78350.1 - 0.00015 20.5 0.0 0.00015 20.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.6 PRP78350.1 - 0.001 19.8 2.0 0.0088 16.8 0.0 3.4 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase TMEM239 PF15841.5 PRP78350.1 - 1.2 9.0 2.8 2.4 8.1 2.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family ETRAMP PF09716.10 PRP78350.1 - 1.2 9.2 0.0 1.2 9.2 0.0 4.4 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF3886 PF13025.6 PRP78352.1 - 3.3 8.0 13.9 6.5 7.0 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) YecR PF13992.6 PRP78353.1 - 0.0099 16.2 0.5 0.017 15.4 0.5 1.4 1 0 0 1 1 1 1 YecR-like lipoprotein Polyoma_lg_T_C PF06431.11 PRP78353.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus DUF4108 PF13390.6 PRP78354.1 - 3.6e-06 27.0 0.0 0.071 13.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4108) DUF3045 PF11243.8 PRP78354.1 - 0.013 15.6 1.7 19 5.5 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3045) Ac76 PF05814.11 PRP78354.1 - 0.64 10.1 5.2 21 5.2 0.1 3.7 4 0 0 4 4 4 0 Orf76 (Ac76) ATP_bind_3 PF01171.20 PRP78355.1 - 3e-30 105.3 0.2 6e-30 104.3 0.2 1.4 1 1 0 1 1 1 1 PP-loop family CIAPIN1 PF05093.13 PRP78356.1 - 5.3e-19 68.6 13.3 2.2e-13 50.5 2.0 2.7 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Ras PF00071.22 PRP78357.1 - 7.7e-58 194.7 0.1 9e-58 194.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP78357.1 - 5.8e-33 113.6 0.0 8.9e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP78357.1 - 2e-17 63.2 0.0 2.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP78357.1 - 3.5e-08 33.1 0.1 4.3e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP78357.1 - 0.00027 20.5 0.1 0.00059 19.4 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP78357.1 - 0.00059 19.9 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PRP78357.1 - 0.0016 17.7 0.8 0.4 9.8 0.1 2.8 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PRP78357.1 - 0.0027 17.2 0.1 0.0065 15.9 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PRP78357.1 - 0.0069 16.3 0.4 1.1 9.2 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PRP78357.1 - 0.034 14.4 0.0 0.12 12.7 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 PRP78357.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 PRP78357.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP78357.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ChaC PF04752.12 PRP78358.1 - 7.1e-37 127.2 0.0 8.6e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein GGACT PF06094.12 PRP78358.1 - 0.0004 21.0 0.0 0.00054 20.6 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Exo_endo_phos PF03372.23 PRP78359.1 - 3.6e-24 85.6 0.1 5.3e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ras PF00071.22 PRP78360.1 - 7.6e-51 171.9 0.0 8.9e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP78360.1 - 2e-15 57.1 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP78360.1 - 8.4e-07 28.6 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP78360.1 - 0.0023 17.5 0.0 0.0047 16.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP78360.1 - 0.011 15.7 0.1 0.025 14.5 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AlaDh_PNT_C PF01262.21 PRP78360.1 - 0.071 12.4 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain G-alpha PF00503.20 PRP78360.1 - 0.12 11.5 0.0 0.86 8.7 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit TAN PF11640.8 PRP78360.1 - 0.15 12.2 0.0 14 5.8 0.0 2.1 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair EF-hand_1 PF00036.32 PRP78361.1 - 2.3e-10 39.2 0.0 1e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP78361.1 - 2.6e-10 39.4 0.0 1.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PRP78361.1 - 1.7e-08 34.8 0.1 2.5e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP78361.1 - 5.3e-08 32.0 0.0 0.00038 19.8 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PRP78361.1 - 0.0089 15.9 0.0 2.5 8.0 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair B56 PF01603.20 PRP78362.1 - 4.1e-112 375.2 3.8 5e-112 374.9 3.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF1864 PF08933.11 PRP78362.1 - 0.021 13.6 0.1 0.05 12.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) F-box PF00646.33 PRP78363.1 - 3.6e-09 36.3 0.0 1.1e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP78363.1 - 9.2e-05 22.3 1.3 0.00028 20.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like FYVE_2 PF02318.16 PRP78363.1 - 0.0037 17.5 3.8 0.0037 17.5 3.8 2.6 3 0 0 3 3 3 1 FYVE-type zinc finger WD40 PF00400.32 PRP78363.1 - 0.048 14.6 0.9 2.9 8.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 PRP78363.1 - 0.15 11.1 0.0 0.43 9.6 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region Siva PF05458.12 PRP78363.1 - 8.4 6.0 12.5 0.21 11.3 4.9 2.2 2 0 0 2 2 2 0 Cd27 binding protein (Siva) ubiquitin PF00240.23 PRP78364.1 - 3e-103 337.7 15.2 5.5e-34 115.7 0.9 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 PRP78364.1 - 2.9e-48 161.6 16.0 1.1e-15 57.2 1.0 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP78364.1 - 8.8e-19 67.8 7.2 9.9e-05 22.7 0.2 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 PRP78364.1 - 1.6e-12 47.2 3.5 0.011 15.7 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP78364.1 - 4.7e-12 46.1 4.2 0.012 15.9 0.2 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP78364.1 - 4.8e-12 46.0 1.9 0.033 14.3 0.0 4.0 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PRP78364.1 - 1.7e-11 44.6 0.7 0.052 14.1 0.0 3.1 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 PRP78364.1 - 3.7e-08 33.4 0.2 0.44 10.4 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 PRP78364.1 - 1.3e-06 28.3 17.3 7 6.8 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 PRP78364.1 - 2.1e-05 24.6 1.7 4.3 7.6 0.1 3.2 3 0 0 3 3 3 3 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 PRP78364.1 - 0.0003 21.1 0.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) DUF493 PF04359.14 PRP78364.1 - 0.001 19.6 0.1 30 5.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF493) ACT_5 PF13710.6 PRP78364.1 - 0.001 18.9 3.2 10 6.1 0.1 3.3 3 0 0 3 3 3 0 ACT domain DUF1940 PF09155.10 PRP78364.1 - 0.001 19.2 2.8 12 6.0 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1940) Methyltrans_RNA PF04452.14 PRP78364.1 - 0.0013 18.1 0.2 1.6 8.0 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_3_3 PF13750.6 PRP78364.1 - 0.0017 18.0 0.0 20 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Big_7 PF17957.1 PRP78364.1 - 0.0021 18.8 0.1 41 5.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain Raf1_HTH PF18579.1 PRP78364.1 - 0.0022 17.7 0.5 26 4.6 0.0 3.3 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain TmoB PF06234.12 PRP78364.1 - 0.0043 17.1 3.1 22 5.2 0.1 3.8 3 3 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) DUF969 PF06149.12 PRP78364.1 - 0.0079 15.6 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 PRP78364.1 - 0.0087 16.6 0.6 58 4.4 0.0 3.3 3 0 0 3 3 3 0 ACT domain UDP-g_GGTase PF06427.11 PRP78364.1 - 0.012 15.8 3.8 4.3 7.5 0.1 3.2 4 0 0 4 4 3 0 UDP-glucose:Glycoprotein Glucosyltransferase ProRS-C_2 PF09181.10 PRP78364.1 - 0.046 13.9 2.9 48 4.2 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal ORF11CD3 PF10549.9 PRP78364.1 - 0.093 12.9 1.2 62 3.8 0.0 4.0 6 0 0 6 6 3 0 ORF11CD3 domain PI3K_p85B PF02192.16 PRP78364.1 - 0.1 12.3 6.1 24 4.7 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Baculo_p48 PF04878.13 PRP78364.1 - 0.11 11.4 0.1 14 4.4 0.0 2.4 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 PRP78364.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif DMA PF03474.14 PRP78364.1 - 0.27 10.9 1.5 72 3.1 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Myosin_N PF02736.19 PRP78364.1 - 0.36 10.7 3.4 76 3.3 0.0 4.0 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain Plexin_cytopl PF08337.12 PRP78364.1 - 1.1 7.8 13.9 7.1 5.2 0.7 4.0 3 2 0 4 4 4 0 Plexin cytoplasmic RasGAP domain Phage_sheath_1N PF17481.2 PRP78364.1 - 1.7 9.1 5.6 47 4.5 1.6 3.0 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain Cnl2_NKP2 PF09447.10 PRP78364.1 - 8.7 6.6 7.8 1e+02 3.1 0.2 3.4 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Ank_2 PF12796.7 PRP78365.1 - 4.3e-32 110.5 0.0 2.8e-07 31.0 0.0 5.4 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) AA_kinase PF00696.28 PRP78365.1 - 2.6e-25 89.4 0.1 6.2e-25 88.2 0.1 1.6 1 0 0 1 1 1 1 Amino acid kinase family Ank_4 PF13637.6 PRP78365.1 - 5.3e-21 74.7 2.3 0.0015 19.0 0.0 6.9 5 2 2 7 7 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP78365.1 - 1e-15 57.5 4.0 0.099 13.0 0.0 9.3 2 2 7 9 9 9 4 Ankyrin repeats (many copies) Aldedh PF00171.22 PRP78365.1 - 1.1e-15 57.1 0.7 8.4e-10 37.7 0.0 2.8 3 0 0 3 3 3 2 Aldehyde dehydrogenase family VIT1 PF01988.19 PRP78365.1 - 3.5e-15 56.5 0.0 1.4e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 VIT family Ank_3 PF13606.6 PRP78365.1 - 3.5e-13 48.4 0.4 0.21 12.2 0.0 9.3 9 0 0 9 9 8 2 Ankyrin repeat Ank PF00023.30 PRP78365.1 - 1.6e-09 37.7 1.2 34 5.1 0.0 9.5 7 3 1 8 8 8 0 Ankyrin repeat Syntaxin_2 PF14523.6 PRP78365.1 - 0.016 15.6 4.1 0.032 14.6 0.3 2.9 2 0 0 2 2 2 0 Syntaxin-like protein PrpR_N PF06506.11 PRP78365.1 - 0.054 13.1 0.3 2.3 7.8 0.1 2.8 2 0 0 2 2 2 0 Propionate catabolism activator SpoU_sub_bind PF08032.12 PRP78365.1 - 0.067 13.5 2.6 20 5.5 0.1 5.3 5 0 0 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding SET PF00856.28 PRP78367.1 - 4.3e-20 72.8 0.1 1.3e-19 71.2 0.1 1.9 1 0 0 1 1 1 1 SET domain PHD PF00628.29 PRP78367.1 - 2.3e-18 65.8 70.2 1.7e-10 40.6 6.8 6.7 6 1 1 7 7 7 3 PHD-finger zf-HC5HC2H PF13771.6 PRP78367.1 - 2.8e-08 33.9 5.1 2.8e-08 33.9 5.1 5.3 4 1 1 5 5 5 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PRP78367.1 - 3.4e-08 33.6 8.1 3.4e-08 33.6 8.1 4.6 3 2 1 4 4 4 1 PHD-zinc-finger like domain FYRN PF05964.14 PRP78367.1 - 3.7e-08 33.1 0.0 1.3e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 F/Y-rich N-terminus Myb_DNA-binding PF00249.31 PRP78367.1 - 0.00051 20.2 0.4 0.0015 18.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain PHD_2 PF13831.6 PRP78367.1 - 0.011 15.3 0.5 0.011 15.3 0.5 4.9 5 0 0 5 5 5 0 PHD-finger C1_1 PF00130.22 PRP78367.1 - 0.013 15.4 0.5 0.013 15.4 0.5 6.9 6 1 1 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYRC PF05965.14 PRP78367.1 - 0.081 13.1 0.0 2.6 8.3 0.0 2.8 3 0 0 3 3 3 0 F/Y rich C-terminus DUF4176 PF13780.6 PRP78367.1 - 0.1 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) DHR-2 PF06920.13 PRP78369.1 - 4.8e-135 451.2 10.8 8e-135 450.5 10.8 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 PRP78369.1 - 6.8e-31 107.6 1.0 1.6e-30 106.3 1.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins MitMem_reg PF13012.6 PRP78371.1 - 0.06 13.8 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function RSN1_7TM PF02714.15 PRP78372.1 - 1e-60 205.4 31.7 1.1e-34 120.0 8.3 3.4 3 2 1 4 4 4 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PRP78372.1 - 9.8e-33 113.1 9.0 9.8e-33 113.1 9.0 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PRP78372.1 - 2.1e-16 60.7 0.3 3.2e-16 60.1 0.3 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TetR_C_20 PF17925.1 PRP78372.1 - 0.067 13.5 0.3 15 5.9 0.0 3.1 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Syndecan PF01034.20 PRP78372.1 - 1.3 8.9 8.4 7.8 6.5 1.5 3.4 2 0 0 2 2 2 0 Syndecan domain Aminotran_1_2 PF00155.21 PRP78373.1 - 2.6e-34 119.0 0.0 3.4e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 PRP78373.1 - 9e-06 26.3 6.3 0.0054 17.6 0.1 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat RRM_1 PF00076.22 PRP78374.1 - 1.5e-09 37.5 0.0 5.9e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 PRP78374.1 - 0.00041 19.6 5.7 0.00065 19.0 5.7 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Actin PF00022.19 PRP78375.1 - 3.7e-88 295.9 0.0 1.7e-86 290.4 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 PRP78375.1 - 0.004 17.5 0.0 0.037 14.4 0.0 2.2 2 0 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 PRP78375.1 - 0.19 10.5 0.0 8.1 5.2 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Sel_put PF04328.13 PRP78376.1 - 0.0014 18.6 1.1 2.2 8.4 0.0 2.5 2 0 0 2 2 2 2 Selenoprotein, putative CSRNP_N PF16019.5 PRP78376.1 - 0.092 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4521 PF15021.6 PRP78376.1 - 0.1 12.5 1.4 0.76 9.7 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4521) SecY PF00344.20 PRP78377.1 - 8.5e-73 245.3 6.0 1.1e-72 245.0 6.0 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 PRP78377.1 - 1.4e-19 69.6 0.2 1.4e-19 69.6 0.2 2.9 3 0 0 3 3 3 1 Plug domain of Sec61p DUF2975 PF11188.8 PRP78377.1 - 8.3 6.3 13.6 0.068 13.1 0.7 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2975) Myb_DNA-binding PF00249.31 PRP78379.1 - 0.66 10.2 1.9 0.97 9.7 0.0 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain IPK PF03770.16 PRP78380.1 - 7e-52 176.2 0.1 1.1e-51 175.6 0.1 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase JAB PF01398.21 PRP78381.1 - 8.1e-23 80.7 0.0 1.4e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PRP78381.1 - 3.8e-10 39.6 0.0 5.7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Orthopox_F7 PF05813.12 PRP78381.1 - 0.065 13.3 0.1 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Orthopoxvirus F7 protein DUF3208 PF11482.8 PRP78381.1 - 0.18 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) TMEMspv1-c74-12 PF11044.8 PRP78382.1 - 0.19 11.8 1.3 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein LapA_dom PF06305.11 PRP78382.1 - 1.9 8.4 3.3 0.87 9.5 0.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain HA PF03457.14 PRP78383.1 - 1.3e-16 60.7 2.9 2.8e-16 59.6 2.9 1.6 1 0 0 1 1 1 1 Helicase associated domain Ribonuc_red_sm PF00268.21 PRP78384.1 - 3.9e-116 387.4 0.4 4.8e-116 387.1 0.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain QH-AmDH_gamma PF08992.11 PRP78384.1 - 0.078 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit TLD PF07534.16 PRP78385.1 - 1.3e-18 67.6 0.3 3e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 TLD RabGAP-TBC PF00566.18 PRP78385.1 - 0.017 14.8 3.1 0.09 12.4 0.4 2.9 2 1 0 2 2 2 0 Rab-GTPase-TBC domain HTH_39 PF14090.6 PRP78385.1 - 0.18 11.6 0.0 0.49 10.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_4 PF12799.7 PRP78386.1 - 2.5e-18 65.9 6.9 2.9e-08 33.9 0.1 5.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP78386.1 - 1.8e-17 63.4 0.1 7.5e-13 48.3 0.0 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 PRP78386.1 - 1.2e-11 44.2 2.7 1.6e-06 27.8 0.2 3.2 2 1 0 2 2 2 2 Leucine rich repeat Lung_7-TM_R PF06814.13 PRP78386.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Lung seven transmembrane receptor Exonuc_VII_L PF02601.15 PRP78386.1 - 2.5 7.6 8.8 4.6 6.7 8.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit RICH PF05062.12 PRP78386.1 - 5 7.5 10.8 0.42 11.0 2.0 3.1 3 0 0 3 3 3 0 RICH domain FapA PF03961.13 PRP78386.1 - 9.4 4.7 8.9 16 3.9 8.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A FHA PF00498.26 PRP78387.1 - 1.4e-11 44.6 0.2 3.2e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 FHA domain HLH PF00010.26 PRP78387.1 - 6.4e-07 29.2 0.8 1.7e-06 27.9 0.8 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Yop-YscD_cpl PF16697.5 PRP78387.1 - 9e-07 29.1 0.5 2.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain PH PF00169.29 PRP78387.1 - 0.00035 21.0 0.6 0.00035 21.0 0.6 2.2 2 0 0 2 2 2 1 PH domain Sep15_SelM PF08806.11 PRP78388.1 - 4.5e-11 42.7 0.1 2.7e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Sep15/SelM redox domain Thioredoxin PF00085.20 PRP78388.1 - 0.0046 16.9 0.2 0.57 10.2 0.2 2.2 1 1 1 2 2 2 2 Thioredoxin Mob1_phocein PF03637.17 PRP78389.1 - 7.6e-81 270.1 0.3 9.3e-81 269.8 0.3 1.1 1 0 0 1 1 1 1 Mob1/phocein family DLH PF01738.18 PRP78390.1 - 3.9e-26 91.9 0.0 4.9e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 PRP78390.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP78390.1 - 0.074 12.3 0.1 1.3 8.3 0.0 2.4 2 1 1 3 3 3 0 Serine aminopeptidase, S33 PrgH PF09480.10 PRP78390.1 - 0.21 10.9 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) IPPT PF01715.17 PRP78392.1 - 1.5e-51 175.4 0.5 1.5e-51 175.4 0.5 1.9 2 0 0 2 2 1 1 IPP transferase Ank_2 PF12796.7 PRP78392.1 - 2e-18 66.8 1.1 8.9e-07 29.4 0.0 4.5 4 1 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78392.1 - 3.5e-13 49.8 2.6 1.4e-05 25.5 0.1 4.5 5 1 1 6 6 4 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP78392.1 - 2.5e-12 46.7 2.0 0.018 15.5 0.0 6.2 5 2 1 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PRP78392.1 - 2.9e-10 40.2 0.2 0.00027 21.2 0.1 4.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) SAP PF02037.27 PRP78392.1 - 1.7e-08 34.0 0.6 1.7e-08 34.0 0.6 2.3 2 0 0 2 2 2 1 SAP domain Ank_3 PF13606.6 PRP78392.1 - 2.9e-08 33.3 4.6 0.33 11.7 0.0 6.0 8 0 0 8 8 5 3 Ankyrin repeat zf-C2H2_jaz PF12171.8 PRP78392.1 - 4.7e-06 26.7 3.4 1.7e-05 24.9 3.4 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.16 PRP78392.1 - 2e-05 24.1 0.2 0.0002 20.8 0.1 2.6 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.7 PRP78392.1 - 4.8e-05 23.6 1.6 0.00019 21.7 1.6 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_28 PF13521.6 PRP78392.1 - 0.032 14.5 0.1 3.7 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 PRP78392.1 - 0.065 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 PRP78392.1 - 0.065 13.5 0.1 0.29 11.4 0.0 2.2 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 PRP78392.1 - 0.07 12.9 0.0 0.23 11.2 0.0 2.0 1 0 0 1 1 1 0 IstB-like ATP binding protein HeH PF12949.7 PRP78392.1 - 0.1 12.3 0.4 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 HeH/LEM domain Astro_capsid_p PF12226.8 PRP78392.1 - 0.13 11.4 6.6 0.28 10.3 6.6 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nfu_N PF08712.11 PRP78392.1 - 0.14 12.2 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal NB PF04159.13 PRP78392.1 - 1 9.4 3.4 6.3 6.9 0.5 2.7 2 0 0 2 2 2 0 NB glycoprotein GCP_C_terminal PF04130.13 PRP78393.1 - 1.6e-49 169.0 9.4 3.4e-49 168.0 8.5 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal MORN PF02493.20 PRP78393.1 - 2.1e-42 140.5 51.6 2.3e-08 33.4 0.5 8.1 8 0 0 8 8 8 7 MORN repeat GCP_N_terminal PF17681.1 PRP78393.1 - 7.7e-23 81.6 0.1 1.6e-22 80.6 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal HEPN_AbiU2 PF18734.1 PRP78393.1 - 0.13 11.8 1.8 0.27 10.7 1.0 1.9 2 0 0 2 2 2 0 AbiU2 MORN_2 PF07661.13 PRP78393.1 - 0.25 11.7 20.1 8.3 7.0 0.1 6.3 5 0 0 5 5 5 0 MORN repeat variant Pyr_redox_2 PF07992.14 PRP78394.1 - 4.4e-36 124.6 0.0 6.1e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP78394.1 - 2.2e-11 44.2 0.0 1.7e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP78394.1 - 2.8e-08 33.8 0.1 0.0034 17.0 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PRP78394.1 - 1.7e-07 30.7 0.0 0.017 14.2 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 PRP78394.1 - 2.8e-07 30.1 0.0 0.0059 15.9 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PRP78394.1 - 8.1e-07 28.5 0.7 0.0014 17.9 0.0 3.2 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 PRP78394.1 - 3.6e-05 23.4 0.0 0.0079 15.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) Trp_halogenase PF04820.14 PRP78394.1 - 0.00011 21.2 0.2 0.11 11.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 PRP78394.1 - 0.00012 22.3 0.0 0.53 10.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 PRP78394.1 - 0.00012 22.3 0.0 0.4 11.0 0.0 2.7 2 0 0 2 2 2 2 TrkA-N domain Sacchrp_dh_NADP PF03435.18 PRP78394.1 - 0.00026 21.3 0.1 0.26 11.5 0.0 3.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 PRP78394.1 - 0.00029 21.2 0.0 0.32 11.4 0.0 2.9 2 1 1 3 3 3 1 Putative NAD(P)-binding GIDA PF01134.22 PRP78394.1 - 0.0014 17.8 0.1 0.56 9.2 0.0 2.6 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 PRP78394.1 - 0.0014 17.4 0.0 0.073 11.8 0.0 3.1 4 0 0 4 4 4 1 HI0933-like protein ApbA PF02558.16 PRP78394.1 - 0.018 14.7 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 PRP78394.1 - 0.019 14.3 0.0 2.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 PRP78394.1 - 0.073 12.3 0.1 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 PRP78394.1 - 0.094 12.8 0.1 9.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 PRP78394.1 - 0.11 10.9 0.0 12 4.2 0.0 2.4 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like XdhC_C PF13478.6 PRP78394.1 - 0.11 13.0 0.0 0.41 11.2 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 PRP78394.1 - 0.11 11.8 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 PRP78394.1 - 0.16 11.1 0.9 7.1 5.6 0.0 2.7 2 1 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 PRP78394.1 - 0.16 11.9 4.0 6.6 6.7 0.0 3.5 2 2 1 4 4 4 0 FAD-NAD(P)-binding WD40 PF00400.32 PRP78395.1 - 2.6e-21 75.5 22.1 0.00021 22.0 0.7 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP78395.1 - 0.0013 19.0 0.5 1.7 9.0 0.0 4.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP78395.1 - 0.0015 17.9 0.0 0.0085 15.5 0.0 2.2 1 1 0 1 1 1 1 WD40-like domain YajC PF02699.15 PRP78395.1 - 0.19 11.7 0.0 0.93 9.4 0.0 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit PQQ_3 PF13570.6 PRP78395.1 - 1 10.0 6.8 1.9e+02 2.7 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain EMP24_GP25L PF01105.24 PRP78396.1 - 7.5e-38 130.3 0.0 9e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dfp1_Him1_M PF08630.10 PRP78396.1 - 0.014 15.6 0.4 0.022 15.0 0.4 1.2 1 0 0 1 1 1 0 Dfp1/Him1, central region WD40 PF00400.32 PRP78397.1 - 6.6e-37 124.9 17.8 8.7e-09 35.9 0.3 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP78397.1 - 1.3e-18 67.0 0.1 0.00033 20.9 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 PRP78397.1 - 3.5e-10 39.2 7.7 8.4e-10 38.0 7.7 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 PRP78397.1 - 2.2e-06 26.9 0.2 0.026 13.5 0.0 3.7 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PRP78397.1 - 0.084 12.8 0.1 2.9 7.9 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat GspH PF12019.8 PRP78397.1 - 0.1 13.0 0.1 15 6.1 0.0 3.4 1 1 2 3 3 3 0 Type II transport protein GspH WD40_like PF17005.5 PRP78397.1 - 0.13 11.5 0.0 1.2 8.4 0.0 2.1 1 1 1 2 2 2 0 WD40-like domain DUF647 PF04884.14 PRP78398.1 - 1.7e-91 306.1 0.7 2.3e-91 305.7 0.7 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis PUFD PF16553.5 PRP78398.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain B9-C2 PF07162.11 PRP78399.1 - 1.8e-27 96.6 0.2 6.2e-27 94.9 0.2 1.9 1 1 0 1 1 1 1 Ciliary basal body-associated, B9 protein PPR_long PF17177.4 PRP78400.1 - 2.4e-06 27.1 0.9 0.017 14.5 0.1 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP COX5A PF02284.16 PRP78400.1 - 3.5e-06 27.0 0.6 0.22 11.6 0.1 3.3 2 1 1 3 3 3 2 Cytochrome c oxidase subunit Va PPR PF01535.20 PRP78400.1 - 8e-05 22.6 0.8 0.63 10.4 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 PRP78400.1 - 0.00016 21.8 0.0 0.22 11.8 0.0 3.8 4 0 0 4 4 4 1 PPR repeat family RPAP3_C PF13877.6 PRP78400.1 - 0.042 14.4 3.3 0.13 12.8 0.1 3.2 4 1 1 5 5 5 0 Potential Monad-binding region of RPAP3 TPR_6 PF13174.6 PRP78400.1 - 0.11 13.2 0.1 11 6.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP78400.1 - 0.26 11.5 1.1 1.6 9.0 1.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SNF2_N PF00176.23 PRP78401.1 - 6.1e-78 262.0 0.0 1.3e-77 261.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ank_2 PF12796.7 PRP78401.1 - 0.00026 21.5 0.0 0.00073 20.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Helicase_C PF00271.31 PRP78401.1 - 0.00073 19.9 0.0 0.0025 18.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78401.1 - 0.017 15.2 0.1 0.36 10.8 0.0 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Ank_4 PF13637.6 PRP78401.1 - 0.021 15.4 0.1 2.8 8.6 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP78401.1 - 0.051 13.5 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 F-box-like HypA PF01155.19 PRP78401.1 - 2.4 8.2 4.8 0.89 9.6 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Mit_KHE1 PF10173.9 PRP78401.1 - 2.5 8.2 4.5 0.73 9.9 0.4 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF4407 PF14362.6 PRP78402.1 - 2.3 7.5 18.0 2.2 7.5 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) V-SNARE_C PF12352.8 PRP78404.1 - 1.1e-09 38.5 3.0 1.3e-08 35.0 3.0 2.4 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 PRP78404.1 - 0.0035 17.7 2.2 0.0069 16.7 0.6 2.4 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 PRP78404.1 - 0.0055 16.6 1.1 0.027 14.4 0.0 2.4 1 1 1 3 3 3 1 Sec20 DUF3334 PF11813.8 PRP78404.1 - 0.03 14.0 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) YqjK PF13997.6 PRP78404.1 - 0.034 14.4 1.3 0.29 11.4 0.3 2.6 3 0 0 3 3 3 0 YqjK-like protein RRF PF01765.19 PRP78404.1 - 0.035 14.1 1.3 0.14 12.1 1.3 2.0 1 1 0 1 1 1 0 Ribosome recycling factor DUF3552 PF12072.8 PRP78404.1 - 0.041 13.3 4.4 0.065 12.6 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PhoU PF01895.19 PRP78404.1 - 0.043 14.3 0.3 0.11 13.0 0.3 1.7 1 1 0 1 1 1 0 PhoU domain Orf78 PF06024.12 PRP78404.1 - 0.047 14.0 2.1 0.22 11.8 2.0 2.3 1 1 0 1 1 1 0 Orf78 (ac78) DUF1664 PF07889.12 PRP78404.1 - 0.084 12.9 5.2 0.18 11.8 1.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2207 PF09972.9 PRP78404.1 - 0.16 10.7 0.4 0.68 8.6 0.1 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) YscO-like PF16789.5 PRP78404.1 - 0.2 11.7 5.1 0.2 11.7 3.2 1.8 1 1 1 2 2 2 0 YscO-like protein DUF5345 PF17280.2 PRP78404.1 - 3.1 7.8 6.6 0.36 10.8 2.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) ABC2_membrane PF01061.24 PRP78405.1 - 1.2e-63 214.3 55.7 5.2e-39 133.8 30.7 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 PRP78405.1 - 7.3e-21 75.1 0.0 1.2e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PRP78405.1 - 2.9e-06 27.3 0.0 0.033 14.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PRP78405.1 - 0.00025 21.0 0.2 0.00043 20.2 0.2 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PRP78405.1 - 0.0023 17.6 0.1 0.0049 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP78405.1 - 0.0025 18.2 0.0 0.0045 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PRP78405.1 - 0.017 15.4 0.0 0.067 13.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain PDR_CDR PF06422.12 PRP78405.1 - 0.038 13.9 0.1 0.038 13.9 0.1 3.6 4 1 0 4 4 3 0 CDR ABC transporter AAA_18 PF13238.6 PRP78405.1 - 0.053 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PRP78405.1 - 0.083 12.5 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PRP78405.1 - 0.17 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PRP78405.1 - 0.18 12.1 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain ARD PF03079.14 PRP78406.1 - 6e-41 140.2 0.1 7.4e-41 139.9 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 PRP78406.1 - 2.7e-08 33.4 0.0 6.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 PRP78406.1 - 1.4e-06 28.2 0.0 2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 PRP78406.1 - 0.0016 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AbiEi_4 PF13338.6 PRP78406.1 - 0.015 15.4 0.0 9.7 6.4 0.0 2.8 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin Cupin_3 PF05899.12 PRP78406.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Swi5 PF07061.11 PRP78407.1 - 8.1e-18 64.3 3.2 1.1e-17 63.9 3.2 1.4 1 1 0 1 1 1 1 Swi5 GTP_EFTU PF00009.27 PRP78408.1 - 4.3e-34 117.8 0.1 9.5e-34 116.6 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PRP78408.1 - 1.1e-16 60.8 0.0 3.4e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 PRP78408.1 - 3.2e-09 36.9 0.1 1.2e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 PRP78408.1 - 0.00029 21.0 0.0 0.00066 19.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PRP78408.1 - 0.0011 18.9 0.6 0.061 13.2 0.0 2.7 1 1 1 2 2 2 1 RsgA GTPase GTP_EFTU_D4 PF14578.6 PRP78408.1 - 0.0015 18.4 0.1 0.0038 17.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.10 PRP78408.1 - 0.0023 17.4 0.0 0.0069 15.8 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PRP78408.1 - 0.004 16.8 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.25 PRP78408.1 - 0.036 14.5 0.1 0.15 12.5 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 HD PF01966.22 PRP78409.1 - 2.2e-07 31.1 0.0 5.3e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 PRP78409.1 - 0.04 13.4 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 HDOD domain T_hemolysin PF12261.8 PRP78409.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Thermostable hemolysin Methyltransf_31 PF13847.6 PRP78410.1 - 1.5e-17 63.8 0.1 2.1e-17 63.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP78410.1 - 1e-12 48.5 0.0 1.9e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP78410.1 - 1.1e-11 45.3 0.0 1.4e-10 41.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP78410.1 - 1.5e-11 44.4 0.0 3.9e-11 43.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP78410.1 - 5.9e-06 26.9 0.0 1.4e-05 25.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP78410.1 - 9.3e-06 25.3 0.0 0.00024 20.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PRP78410.1 - 0.00014 21.3 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PrmA PF06325.13 PRP78410.1 - 0.00027 20.4 0.0 0.00061 19.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 PRP78410.1 - 0.0059 16.4 0.0 1.3 8.7 0.0 2.1 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 PRP78410.1 - 0.008 15.6 0.0 0.043 13.2 0.0 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB DOT1 PF08123.13 PRP78410.1 - 0.025 14.1 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.12 PRP78410.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 PRP78410.1 - 0.037 14.0 0.1 0.063 13.3 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 PRP78410.1 - 0.052 12.6 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.17 PRP78410.1 - 0.077 12.2 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Homeodomain PF00046.29 PRP78411.1 - 3.6e-14 52.4 2.8 6.5e-14 51.5 2.8 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP78411.1 - 0.0019 18.1 0.9 0.0037 17.1 0.9 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PRP78412.1 - 8.1e-15 54.4 2.2 1.3e-14 53.8 2.2 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP78412.1 - 4.5e-05 23.3 0.5 7.6e-05 22.5 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain CCDC144C PF14915.6 PRP78416.1 - 0.071 12.2 2.8 2.8 7.0 0.4 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region MG4 PF17789.1 PRP78417.1 - 0.034 14.3 0.2 0.13 12.5 0.2 2.0 1 0 0 1 1 1 0 Macroglobulin domain MG4 V-SNARE PF05008.15 PRP78417.1 - 0.046 14.1 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Myotub-related PF06602.14 PRP78418.1 - 5.4e-119 397.2 0.0 9.7e-119 396.4 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain 3-PAP PF12578.8 PRP78418.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Myotubularin-associated protein DSPc PF00782.20 PRP78418.1 - 0.0067 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP78418.1 - 0.023 14.3 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP78418.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family CdiI_4 PF18624.1 PRP78419.1 - 0.3 11.6 1.6 29 5.2 0.1 2.8 3 0 0 3 3 3 0 CDI immunity protein PAS_9 PF13426.7 PRP78420.1 - 2.6e-08 34.1 0.2 0.00037 20.7 0.0 3.7 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 PRP78420.1 - 4.9e-06 26.5 0.3 0.0019 18.2 0.0 3.5 3 1 0 3 3 3 1 PAS fold PAS_3 PF08447.12 PRP78420.1 - 5.9e-06 26.5 0.1 2.8e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 PRP78420.1 - 0.0044 17.0 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 PRP78420.1 - 0.011 16.0 0.0 24 5.2 0.0 3.9 5 0 0 5 5 5 0 PAS fold DUF4450 PF14614.6 PRP78420.1 - 0.039 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Glyco_hydro_72 PF03198.14 PRP78421.1 - 4.9e-101 338.1 1.9 7.2e-101 337.6 1.9 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 PRP78421.1 - 3.3e-10 40.5 1.0 8.8e-10 39.1 1.0 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 PRP78421.1 - 4.3e-05 22.8 4.6 0.0003 20.0 2.8 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 PRP78421.1 - 0.03 13.8 0.0 0.2 11.1 0.0 2.1 1 1 1 2 2 2 0 Cellulase (glycosyl hydrolase family 5) p450 PF00067.22 PRP78422.1 - 2.2e-38 132.2 0.0 2.8e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IQ PF00612.27 PRP78423.1 - 1.4e-64 207.8 168.1 0.00028 20.4 2.4 31.7 33 0 0 33 33 33 26 IQ calmodulin-binding motif Arm PF00514.23 PRP78423.1 - 0.21 11.7 0.7 6.2 7.0 0.0 3.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat LZ3wCH PF18517.1 PRP78423.1 - 0.47 10.6 5.2 1.3 9.2 5.2 1.7 1 0 0 1 1 1 0 Leucine zipper with capping helix domain PAN_4 PF14295.6 PRP78424.1 - 3e-36 123.1 28.5 3.1e-11 43.0 2.3 4.6 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 PRP78424.1 - 6.1e-16 58.3 23.9 0.00015 21.8 0.7 4.6 4 0 0 4 4 4 4 PAN-like domain PAN_1 PF00024.26 PRP78424.1 - 2.1e-10 40.4 18.1 0.006 16.5 0.5 4.4 3 1 1 4 4 4 4 PAN domain DPBB_1 PF03330.18 PRP78424.1 - 2.6e-06 27.6 2.3 4.6e-06 26.8 0.2 2.5 2 1 0 2 2 2 1 Lytic transglycolase ubiquitin PF00240.23 PRP78427.1 - 9.1e-05 22.1 0.1 0.00015 21.4 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin family BH3 PF15285.6 PRP78427.1 - 0.038 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Rap_GAP PF02145.15 PRP78428.1 - 1.8e-51 174.4 0.0 3.2e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Ank_2 PF12796.7 PRP78428.1 - 5.6e-26 91.0 0.2 4.2e-09 36.9 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PRP78428.1 - 6.1e-23 80.2 1.4 0.00015 22.1 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PRP78428.1 - 7.6e-23 80.6 1.0 6.5e-09 36.2 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78428.1 - 4.4e-22 75.8 0.8 8.3e-05 22.7 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PRP78428.1 - 5.6e-22 77.5 2.5 9.3e-08 32.2 0.2 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Peptidase_S6 PF02395.16 PRP78428.1 - 0.17 9.9 0.0 0.3 9.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin A1 protease CH PF00307.31 PRP78429.1 - 4.8e-16 58.9 0.0 1.3e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain LAP1C PF05609.12 PRP78429.1 - 0.65 9.0 37.2 1.6 7.7 9.4 2.3 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) DUF525 PF04379.14 PRP78430.1 - 5.6e-22 77.8 0.3 1.6e-21 76.3 0.1 2.0 2 0 0 2 2 2 1 ApaG domain zf-MYND PF01753.18 PRP78430.1 - 3.1e-09 36.8 18.6 7.5e-09 35.5 18.6 1.7 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 PRP78430.1 - 3e-07 30.2 0.8 6.3e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP78430.1 - 0.00021 21.0 0.1 0.00021 21.0 0.1 2.2 2 0 0 2 2 2 1 F-box domain SMI1_KNR4 PF09346.10 PRP78430.1 - 0.0044 17.4 0.0 0.01 16.3 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Na_trans_cytopl PF11933.8 PRP78430.1 - 0.007 16.2 0.3 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 Cytoplasmic domain of voltage-gated Na+ ion channel zf-HIT PF04438.16 PRP78430.1 - 0.18 11.7 7.6 0.45 10.4 7.6 1.7 1 0 0 1 1 1 0 HIT zinc finger TUG-UBL1 PF11470.8 PRP78430.1 - 0.19 12.0 0.7 0.45 10.8 0.7 1.6 1 0 0 1 1 1 0 TUG ubiquitin-like domain DUF325 PF03804.13 PRP78431.1 - 0.11 12.5 0.6 0.34 11.0 0.6 1.8 1 0 0 1 1 1 0 Viral proteins of unknown function Glyco_hydro_cc PF11790.8 PRP78432.1 - 5.3e-61 206.2 4.4 8.6e-61 205.5 4.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fascin PF06268.13 PRP78432.1 - 3.8e-06 27.1 0.1 2.1e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 Fascin domain RicinB_lectin_2 PF14200.6 PRP78432.1 - 0.042 14.6 2.0 0.049 14.4 0.4 2.0 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like U79_P34 PF03064.16 PRP78432.1 - 0.89 8.9 22.0 1.4 8.2 22.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RPN2_C PF18004.1 PRP78432.1 - 1.4 8.8 26.3 2.5 8.0 26.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NARP1 PF12569.8 PRP78432.1 - 4.9 5.9 26.5 6.5 5.5 26.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 PRP78432.1 - 5.2 6.2 7.9 8.5 5.5 7.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.17 PRP78432.1 - 5.4 7.1 8.4 11 6.0 8.4 1.5 1 0 0 1 1 1 0 DDHD domain DUF262 PF03235.14 PRP78432.1 - 5.7 7.0 11.4 9.9 6.3 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 Rcd1 PF04078.13 PRP78433.1 - 5.5e-127 422.4 1.0 6.3e-127 422.2 1.0 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Ndr PF03096.14 PRP78434.1 - 2.7e-48 164.1 0.0 3.7e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family DOMON PF03351.17 PRP78435.1 - 9.5e-67 222.9 6.6 1e-23 83.9 0.0 3.5 3 0 0 3 3 3 3 DOMON domain Homeodomain PF00046.29 PRP78435.1 - 0.0027 17.5 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain MORN PF02493.20 PRP78436.1 - 6.7e-37 123.2 54.7 4.7e-07 29.3 2.0 7.6 8 0 0 8 8 8 7 MORN repeat DUF3048_C PF17479.2 PRP78436.1 - 0.00028 21.2 14.0 0.2 12.1 0.7 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3048) C-terminal domain HTH_43 PF09904.9 PRP78436.1 - 9.1 6.3 6.0 2.2 8.3 0.2 2.6 2 1 1 3 3 3 0 Winged helix-turn helix Zn_clus PF00172.18 PRP78437.1 - 0.00014 21.9 11.4 0.00024 21.2 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_38N PF01074.22 PRP78438.1 - 8.4e-73 245.2 12.3 2.1e-71 240.6 12.3 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP78438.1 - 1.8e-21 77.2 0.0 3.8e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP78438.1 - 6.6e-13 48.6 0.4 2.5e-12 46.8 0.4 2.1 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 PRP78438.1 - 4e-08 32.8 0.2 1.1e-07 31.4 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro38C2 PF17677.1 PRP78438.1 - 0.0025 17.9 0.2 0.012 15.7 0.1 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Cas9_a PF18470.1 PRP78438.1 - 0.028 14.0 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain Glyco_hydro_31 PF01055.26 PRP78440.1 - 2.4e-140 468.6 7.7 3.6e-140 468.0 7.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 PRP78440.1 - 4.6e-21 74.9 0.8 2.3e-20 72.7 0.1 2.6 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 PRP78440.1 - 5.4e-07 29.8 0.4 2e-06 27.9 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) NtCtMGAM_N PF16863.5 PRP78440.1 - 0.037 14.2 0.3 0.19 12.0 0.1 2.2 2 0 0 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase TB2_DP1_HVA22 PF03134.19 PRP78442.1 - 1.8e-24 85.5 4.7 4e-24 84.3 4.7 1.6 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RasGAP PF00616.19 PRP78442.1 - 9.1e-23 81.1 0.0 1.2e-15 57.8 0.1 2.9 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase Gar1 PF04410.14 PRP78442.1 - 6.8e-21 74.7 0.0 6.8e-21 74.7 0.0 2.8 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Hexapep PF00132.24 PRP78442.1 - 1.8e-05 24.2 9.2 0.00063 19.4 4.8 4.1 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) ING PF12998.7 PRP78442.1 - 0.12 13.0 2.8 5.6 7.6 0.0 3.7 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Hexapep_2 PF14602.6 PRP78442.1 - 0.24 11.2 10.0 0.15 11.8 6.7 2.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase DIRP PF06584.13 PRP78443.1 - 2.5e-25 88.7 0.2 6.5e-25 87.4 0.2 1.7 1 0 0 1 1 1 1 DIRP Voltage_CLC PF00654.20 PRP78444.1 - 1.7e-91 307.2 22.1 2.4e-91 306.6 18.4 2.2 1 1 1 2 2 2 1 Voltage gated chloride channel Acyltransferase PF01553.21 PRP78444.1 - 3.5e-21 75.3 0.0 6.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase CBS PF00571.28 PRP78444.1 - 4.1e-13 49.6 0.1 4.7e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain Phage_tail_U PF06141.11 PRP78444.1 - 0.073 13.4 0.0 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 Phage minor tail protein U HATPase_c PF02518.26 PRP78445.1 - 4.9e-25 88.2 0.2 2.5e-24 86.0 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MASE3 PF17159.4 PRP78445.1 - 1.6e-15 57.4 22.5 3.7e-15 56.2 22.5 1.6 1 1 0 1 1 1 1 Membrane-associated sensor domain Homeobox_KN PF05920.11 PRP78445.1 - 8e-15 54.5 0.4 1.9e-14 53.3 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain HisKA PF00512.25 PRP78445.1 - 1.3e-13 50.8 0.0 3.8e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Homeodomain PF00046.29 PRP78445.1 - 7.2e-10 38.6 0.4 2.2e-09 37.0 0.4 1.8 1 0 0 1 1 1 1 Homeodomain PBC PF03792.13 PRP78445.1 - 2.4e-08 34.0 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 PBC domain YdjM PF04307.14 PRP78445.1 - 0.24 10.7 2.6 0.38 10.0 1.6 1.9 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase PS_Dcarbxylase PF02666.15 PRP78447.1 - 3e-24 85.7 0.0 4.3e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Pkinase_Tyr PF07714.17 PRP78449.1 - 1.6e-25 89.9 0.1 2.4e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP78449.1 - 3.1e-19 68.8 40.8 6.2e-05 23.3 0.5 8.5 5 2 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP78449.1 - 9.7e-18 63.7 35.1 4.5e-06 26.3 2.1 7.5 5 2 2 7 7 7 7 Leucine rich repeat Pkinase PF00069.25 PRP78449.1 - 2.8e-15 56.4 0.0 5.3e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP78449.1 - 3.1e-09 37.2 2.6 8.4e-09 35.8 2.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP78449.1 - 0.093 13.3 33.5 1.2 9.9 0.3 9.5 11 1 0 11 11 11 0 Leucine Rich Repeat LRR_9 PF14580.6 PRP78449.1 - 0.94 9.0 9.6 13 5.3 0.0 4.0 2 1 2 4 4 4 0 Leucine-rich repeat Pkinase_Tyr PF07714.17 PRP78451.1 - 4.6e-14 52.3 3.1 4.3e-12 45.9 0.6 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 PRP78451.1 - 1.4e-11 43.9 56.8 0.00019 21.1 1.3 7.2 4 3 2 7 7 7 5 Leucine rich repeat Pkinase PF00069.25 PRP78451.1 - 1.6e-10 40.8 1.7 5.1e-09 35.9 1.7 2.4 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP78451.1 - 2.4e-09 37.3 67.0 0.0022 18.4 4.3 9.6 5 3 1 9 9 9 8 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP78451.1 - 6e-07 29.9 6.1 6e-07 29.9 6.1 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif RhoGEF PF00621.20 PRP78452.1 - 1.3e-42 146.1 0.7 1.3e-42 146.1 0.7 2.1 2 1 0 2 2 1 1 RhoGEF domain PH PF00169.29 PRP78452.1 - 7.9e-19 68.1 0.1 4e-11 43.3 0.1 2.9 2 1 0 2 2 2 2 PH domain PH_6 PF15406.6 PRP78452.1 - 4.3e-07 30.2 0.2 0.0011 19.2 0.0 3.0 2 0 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 PRP78452.1 - 1.3e-06 28.8 0.1 0.053 13.9 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain CDC45 PF02724.14 PRP78452.1 - 0.00041 18.8 26.8 0.00059 18.3 26.8 1.3 1 0 0 1 1 1 1 CDC45-like protein IQ PF00612.27 PRP78452.1 - 0.0057 16.3 1.5 0.012 15.3 1.5 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif CDC27 PF09507.10 PRP78452.1 - 0.17 11.3 37.7 0.27 10.6 37.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.7 PRP78452.1 - 0.84 7.7 20.1 1.2 7.2 20.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LAP1C PF05609.12 PRP78452.1 - 5.8 5.9 22.9 9.4 5.2 22.9 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SLC12 PF03522.15 PRP78452.1 - 7.3 5.5 24.6 13 4.7 24.6 1.5 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 PRP78452.1 - 7.8 6.2 35.3 19 4.9 35.3 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 adh_short PF00106.25 PRP78453.1 - 8.5e-21 74.3 0.2 1.7e-20 73.3 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP78453.1 - 2.1e-17 63.5 0.2 8.1e-09 35.4 0.0 2.9 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.8 PRP78453.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Carboxyl_trans PF01039.22 PRP78454.1 - 2.5e-156 521.2 0.0 5.5e-156 520.1 0.0 1.5 1 1 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 PRP78454.1 - 1.2e-120 403.9 2.4 2.6e-120 402.9 2.4 1.5 1 1 0 1 1 1 1 Acetyl-CoA carboxylase, central region Gpi1 PF05024.15 PRP78454.1 - 4.1e-56 190.0 10.4 8.8e-56 188.9 10.4 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) CPSase_L_D2 PF02786.17 PRP78454.1 - 3.1e-54 183.7 0.1 5.3e-54 182.9 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PRP78454.1 - 1.6e-24 86.5 0.0 4.5e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PRP78454.1 - 3e-18 65.9 0.0 6.8e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PRP78454.1 - 2.5e-10 40.0 0.0 5.1e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 PRP78454.1 - 3.1e-08 33.8 0.2 1.1e-07 32.0 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 PRP78454.1 - 2e-07 30.8 0.2 6.7e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PRP78454.1 - 2.2e-06 27.4 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ABC_tran PF00005.27 PRP78455.1 - 8.1e-28 97.7 0.1 4.8e-27 95.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PRP78455.1 - 7.5e-05 22.7 7.5 0.00015 21.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PRP78455.1 - 0.016 15.6 0.0 0.042 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 PRP78455.1 - 0.069 12.9 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 PRP78455.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 PRP78455.1 - 0.099 12.9 0.5 0.98 9.7 0.5 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit zf-C3HC4_2 PF13923.6 PRP78457.1 - 3.3e-11 42.8 9.7 7.9e-11 41.6 9.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP78457.1 - 5.5e-09 35.8 9.6 1.3e-08 34.5 9.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RAWUL PF16207.5 PRP78457.1 - 1.9e-08 34.9 0.4 7.4e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_2 PF13639.6 PRP78457.1 - 2.2e-07 31.1 9.5 4.3e-07 30.2 9.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP78457.1 - 1.2e-05 25.1 12.4 2.1e-05 24.3 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP78457.1 - 1.3e-05 25.1 6.3 4e-05 23.5 6.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP78457.1 - 3.7e-05 23.6 8.2 0.00011 22.1 8.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PRP78457.1 - 0.0014 18.8 8.7 0.002 18.3 7.4 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PRP78457.1 - 0.0025 17.6 6.1 0.0065 16.2 6.1 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PRP78457.1 - 0.0089 16.3 8.0 0.039 14.2 8.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 PRP78457.1 - 0.016 15.0 5.2 0.032 14.0 5.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SRP-alpha_N PF04086.13 PRP78457.1 - 0.02 14.8 8.4 0.027 14.4 8.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-RING_6 PF14835.6 PRP78457.1 - 0.029 14.2 5.2 0.049 13.5 5.2 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DDHD PF02862.17 PRP78457.1 - 0.19 11.9 4.5 0.26 11.4 4.5 1.3 1 0 0 1 1 1 0 DDHD domain zf-C3HC4_5 PF17121.5 PRP78457.1 - 0.24 11.3 8.3 0.88 9.5 8.3 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP78457.1 - 0.33 10.8 10.8 30 4.6 12.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3337 PF11816.8 PRP78457.1 - 0.44 10.4 7.0 0.15 12.0 2.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3337) DUF2052 PF09747.9 PRP78457.1 - 0.47 10.5 11.6 0.76 9.9 11.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ALMT PF11744.8 PRP78457.1 - 0.66 8.7 5.3 0.75 8.6 5.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Spore_coat_CotO PF14153.6 PRP78457.1 - 0.78 9.6 12.0 1.3 8.9 12.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO FAM176 PF14851.6 PRP78457.1 - 0.92 9.2 6.2 2.3 7.9 6.2 1.7 1 0 0 1 1 1 0 FAM176 family Presenilin PF01080.17 PRP78457.1 - 2.4 6.8 9.0 3.1 6.5 9.0 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rbc25 PF08292.12 PRP78458.1 - 2.2e-30 105.5 0.2 4.5e-30 104.5 0.2 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 PRP78458.1 - 1.4e-15 57.4 0.0 2.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 PRP78458.1 - 0.014 15.8 0.1 0.044 14.1 0.1 1.9 1 1 0 1 1 1 0 S1 RNA binding domain PCRF PF03462.18 PRP78459.1 - 6.5e-63 212.1 2.4 1e-62 211.5 2.4 1.3 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 PRP78459.1 - 8.3e-32 109.5 0.4 8.3e-32 109.5 0.4 2.0 2 0 0 2 2 2 1 RF-1 domain MRP-S27 PF10037.9 PRP78459.1 - 0.075 11.9 4.0 0.15 10.9 4.0 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 FUSC-like PF12805.7 PRP78459.1 - 0.16 11.0 0.4 0.24 10.5 0.4 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS AAA_23 PF13476.6 PRP78459.1 - 0.72 10.3 4.8 0.37 11.3 2.3 1.7 2 0 0 2 2 2 0 AAA domain DNA_pol_A_exo1 PF01612.20 PRP78460.1 - 3.2e-18 66.0 0.0 6.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Ank_2 PF12796.7 PRP78460.1 - 0.039 14.5 0.0 0.17 12.5 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Nop14 PF04147.12 PRP78460.1 - 0.88 7.7 19.6 1.7 6.8 19.6 1.4 1 0 0 1 1 1 0 Nop14-like family VIR_N PF15912.5 PRP78460.1 - 1.1 8.8 9.8 4 7.0 9.8 1.9 1 0 0 1 1 1 0 Virilizer, N-terminal Myc_N PF01056.18 PRP78460.1 - 1.4 8.8 12.2 0.095 12.6 6.9 1.7 2 0 0 2 2 2 0 Myc amino-terminal region NPR3 PF03666.13 PRP78460.1 - 1.8 7.3 7.7 4.3 6.0 7.7 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 PRP78460.1 - 4.2 5.6 14.8 7 4.8 14.8 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 PRP78460.1 - 6.5 7.2 7.5 4.9 7.6 4.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 SspB PF04386.13 PRP78460.1 - 8.5 6.2 8.8 17 5.3 7.0 2.4 2 0 0 2 2 2 0 Stringent starvation protein B DNA_pol_B PF00136.21 PRP78462.1 - 0.0081 14.9 0.2 0.0082 14.9 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B Smg4_UPF3 PF03467.15 PRP78465.1 - 3.6e-43 147.6 0.7 3.6e-43 147.6 0.7 3.1 3 0 0 3 3 3 1 Smg-4/UPF3 family SUIM_assoc PF16619.5 PRP78465.1 - 0.042 13.9 6.0 0.14 12.2 2.6 3.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RRM_2 PF04059.12 PRP78465.1 - 0.079 13.2 0.2 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif 2 NifT PF06988.11 PRP78465.1 - 0.084 12.7 0.6 0.2 11.5 0.1 1.9 2 0 0 2 2 2 0 NifT/FixU protein BRAP2 PF07576.12 PRP78465.1 - 0.13 12.5 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 BRCA1-associated protein 2 PAM2 PF07145.15 PRP78465.1 - 0.2 11.4 0.1 0.2 11.4 0.1 4.1 4 0 0 4 4 4 0 Ataxin-2 C-terminal region Ferlin_C PF16165.5 PRP78465.1 - 8.4 6.3 6.3 3.5 7.5 2.6 2.3 2 0 0 2 2 2 0 Ferlin C-terminus tRNA-synt_1b PF00579.25 PRP78466.1 - 1.3e-59 202.0 0.0 1.7e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DEAD PF00270.29 PRP78467.1 - 1e-43 149.1 0.0 2.1e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP78467.1 - 1.9e-32 111.9 0.4 1.5e-31 109.0 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78467.1 - 3.2e-07 30.5 0.0 5.3e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PRP78467.1 - 0.017 15.5 0.3 0.11 12.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP78467.1 - 0.052 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 PRP78467.1 - 0.084 12.2 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.6 PRP78467.1 - 0.11 12.8 0.5 1.3 9.3 0.5 2.6 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 PRP78467.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Helicase MerR-DNA-bind PF09278.11 PRP78467.1 - 0.12 13.0 0.2 0.41 11.2 0.2 2.0 2 0 0 2 2 2 0 MerR, DNA binding CMS1 PF14617.6 PRP78467.1 - 0.12 11.7 0.2 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rep_fac_C PF08542.11 PRP78468.1 - 2.2e-15 56.8 0.0 4.5e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 PRP78468.1 - 1.2e-10 41.9 0.3 4e-10 40.2 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PRP78468.1 - 2e-09 37.4 0.1 3.2e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 PRP78468.1 - 0.00037 20.8 0.0 0.0012 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 PRP78468.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 PRP78468.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain BTAD PF03704.17 PRP78468.1 - 0.0085 16.5 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial transcriptional activator domain DEAD PF00270.29 PRP78468.1 - 0.029 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 PRP78468.1 - 0.035 13.8 0.2 0.083 12.6 0.2 1.5 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 PRP78469.1 - 2.3e-48 164.1 0.0 3.1e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PRP78469.1 - 2.8e-34 118.5 0.0 4.8e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP78469.1 - 5e-09 36.8 0.0 8.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PRP78469.1 - 4.8e-06 26.8 0.0 1.7e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PRP78469.1 - 0.00076 19.2 0.1 0.54 9.9 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 PRP78469.1 - 0.0052 16.1 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.29 PRP78469.1 - 0.1 13.0 0.1 0.19 12.1 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 PRP78469.1 - 0.14 12.4 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 PRP78469.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PPR_3 PF13812.6 PRP78470.1 - 7.8e-24 83.5 0.7 9.6e-08 32.0 0.0 4.8 2 2 3 5 5 5 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 PRP78470.1 - 1.4e-22 79.7 6.9 3.9e-09 36.6 0.1 4.8 1 1 5 6 6 6 6 PPR repeat family PPR PF01535.20 PRP78470.1 - 4.8e-12 45.3 8.8 0.0011 19.0 0.0 6.3 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 PRP78470.1 - 3.8e-10 39.5 0.0 4.8e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP78470.1 - 1.8e-06 27.5 0.4 0.12 12.1 0.0 5.3 5 2 0 5 5 5 2 PPR repeat Exog_C PF18026.1 PRP78470.1 - 0.011 15.8 0.1 0.061 13.4 0.1 2.2 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain NETI PF14044.6 PRP78470.1 - 0.15 11.8 0.9 25 4.7 0.0 3.1 3 0 0 3 3 3 0 NETI protein Pkinase_Tyr PF07714.17 PRP78473.1 - 1.6e-31 109.5 0.1 2.9e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78473.1 - 5.7e-23 81.6 0.1 1.1e-22 80.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP78473.1 - 1.4e-22 79.3 75.2 4.9e-05 23.6 6.1 10.2 4 2 7 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP78473.1 - 4.3e-18 64.8 55.2 6.2e-06 25.9 2.7 8.1 7 0 0 7 7 7 6 Leucine rich repeat GPS PF01825.21 PRP78473.1 - 6.5e-10 39.4 5.7 1.9e-09 37.9 5.7 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif F-box PF00646.33 PRP78473.1 - 0.043 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 F-box domain EphA2_TM PF14575.6 PRP78473.1 - 0.19 12.6 0.1 2.9 8.8 0.1 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ceramidase PF05875.12 PRP78474.1 - 1.3e-60 205.1 13.7 1.4e-60 204.9 13.7 1.0 1 0 0 1 1 1 1 Ceramidase ECF_trnsprt PF12822.7 PRP78474.1 - 0.061 13.4 9.9 0.42 10.7 9.7 2.3 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DUF3377 PF11857.8 PRP78474.1 - 0.062 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) YrhK PF14145.6 PRP78474.1 - 1.3 8.9 7.4 24 4.9 4.7 3.3 2 1 0 2 2 2 0 YrhK-like protein CTP_transf_1 PF01148.20 PRP78474.1 - 3.5 7.3 10.3 3.9 7.2 9.1 1.6 1 1 0 1 1 1 0 Cytidylyltransferase family Leader_Trp PF08255.11 PRP78474.1 - 10 6.4 9.6 0.36 10.9 2.5 2.5 2 0 0 2 2 2 0 Trp-operon Leader Peptide Bcl-2 PF00452.19 PRP78476.1 - 0.098 13.4 0.0 0.73 10.6 0.0 2.6 3 1 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Prothymosin PF03247.14 PRP78476.1 - 0.68 10.4 24.9 1.3 9.5 24.9 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Paf1 PF03985.13 PRP78476.1 - 1.2 8.1 17.8 2.2 7.2 17.8 1.3 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 PRP78476.1 - 1.9 7.8 15.2 3.3 7.0 15.2 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 PRP78476.1 - 9.1 5.5 10.5 17 4.6 10.5 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 PRP78476.1 - 9.5 5.5 18.1 22 4.4 18.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Torsin PF06309.11 PRP78477.1 - 2.3e-07 30.9 0.0 6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Torsin AAA_22 PF13401.6 PRP78477.1 - 7.1e-06 26.3 0.6 0.00088 19.6 0.6 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 PRP78477.1 - 0.0024 18.3 0.1 0.0056 17.1 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP78477.1 - 0.0025 17.8 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP78477.1 - 0.006 17.0 0.1 1.1 9.7 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 PRP78477.1 - 0.018 15.1 1.0 0.037 14.1 0.2 1.8 2 1 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 PRP78477.1 - 0.053 12.8 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 PRP78477.1 - 0.12 11.7 0.1 3 7.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein TMEM232 PF15877.5 PRP78478.1 - 0.17 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 232 UPF0239 PF06783.11 PRP78479.1 - 0.036 14.3 0.1 0.072 13.3 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF4062 PF13271.6 PRP78479.1 - 0.041 14.2 0.5 0.08 13.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) CAF1 PF04857.20 PRP78480.1 - 4.4e-74 249.5 0.0 5.3e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 PRP78480.1 - 3e-05 23.9 0.1 6.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 RNA binding domain GAD-like PF08887.11 PRP78480.1 - 0.013 15.2 0.1 1.2 9.0 0.0 3.3 3 1 1 4 4 4 0 GAD-like domain DNA_pol_A_exo1 PF01612.20 PRP78480.1 - 0.015 15.0 0.0 0.73 9.5 0.0 2.6 3 0 0 3 3 3 0 3'-5' exonuclease NCBP3 PF10309.9 PRP78480.1 - 0.026 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 TPR_2 PF07719.17 PRP78481.1 - 0.014 15.5 0.0 9.9 6.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4080 PF13311.6 PRP78481.1 - 0.015 15.5 0.6 0.55 10.4 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) Uds1 PF15456.6 PRP78481.1 - 0.046 13.9 0.3 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Up-regulated During Septation F-box PF00646.33 PRP78482.1 - 5e-06 26.3 0.2 1.6e-05 24.7 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP78482.1 - 0.0027 17.6 0.1 0.0068 16.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF1924 PF09086.11 PRP78482.1 - 0.0063 16.9 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1924) Ank_4 PF13637.6 PRP78482.1 - 0.011 16.3 0.0 21 5.8 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) F-box_4 PF15966.5 PRP78482.1 - 0.036 13.9 0.5 0.036 13.9 0.5 2.8 2 1 1 3 3 3 0 F-box Spidroin_MaSp PF11260.8 PRP78483.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 Methyltrans_RNA PF04452.14 PRP78483.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Kdo PF06293.14 PRP78485.1 - 2e-07 30.6 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PRP78485.1 - 8.5e-07 28.6 0.0 2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP78485.1 - 2.1e-05 24.6 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 PRP78485.1 - 8.6e-05 22.3 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 PRP78485.1 - 8.9e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 PRP78485.1 - 0.0002 21.0 0.1 0.0024 17.5 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 PRP78485.1 - 0.0038 16.5 0.0 0.0069 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEPN_Swt1 PF18731.1 PRP78485.1 - 0.069 13.5 0.0 4.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Swt1-like HEPN Ank_5 PF13857.6 PRP78485.1 - 0.14 12.6 0.0 0.47 10.8 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP78485.1 - 0.15 12.7 0.0 0.4 11.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) MPM1 PF17234.2 PRP78487.1 - 2.1 8.6 14.7 1.3 9.3 4.1 2.4 1 1 1 2 2 2 0 Mitochondrial peculiar membrane protein 1 DNA_pol_B PF00136.21 PRP78488.1 - 0.004 15.9 1.5 0.0058 15.4 1.5 1.2 1 0 0 1 1 1 1 DNA polymerase family B DUF3828 PF12883.7 PRP78489.1 - 0.081 13.3 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) LapA_dom PF06305.11 PRP78489.1 - 0.087 12.7 3.9 1.6 8.6 0.3 3.4 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain NADH_u_ox_C PF12853.7 PRP78489.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF1043 PF06295.12 PRP78489.1 - 1.8 8.6 6.7 43 4.1 6.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Actin PF00022.19 PRP78490.1 - 7.5e-45 153.2 0.0 1.2e-44 152.5 0.0 1.3 1 0 0 1 1 1 1 Actin Arg_repressor_C PF02863.18 PRP78490.1 - 0.0074 16.1 0.5 0.73 9.7 0.0 2.4 2 0 0 2 2 2 2 Arginine repressor, C-terminal domain Actin PF00022.19 PRP78491.1 - 2.5e-72 243.7 0.0 4.2e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Actin Aldo_ket_red PF00248.21 PRP78491.1 - 5.1e-36 124.4 0.4 7.6e-35 120.5 0.4 2.6 1 1 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 PRP78491.1 - 0.00011 22.7 0.0 0.00043 20.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78491.1 - 0.0018 18.8 0.0 4.6 8.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Surp PF01805.20 PRP78492.1 - 6.7e-20 70.8 0.5 6.4e-09 35.7 0.1 2.8 2 1 0 2 2 2 2 Surp module DRY_EERY PF09750.9 PRP78492.1 - 1.7e-15 57.5 0.4 1.7e-15 57.5 0.4 2.8 3 0 0 3 3 3 1 Alternative splicing regulator DUF1003 PF06210.11 PRP78492.1 - 0.52 10.4 0.0 0.52 10.4 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) Myco_haema PF05692.12 PRP78492.1 - 3.8 6.4 5.5 7.7 5.4 5.3 1.6 1 1 1 2 2 2 0 Mycoplasma haemagglutinin CN_hydrolase PF00795.22 PRP78493.1 - 1.4e-37 129.4 0.0 2.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 PRP78493.1 - 8.9e-26 90.5 0.0 1.9e-25 89.4 0.0 1.5 1 1 0 1 1 1 1 NAD synthase FtsJ PF01728.19 PRP78494.1 - 2.2e-28 99.6 0.0 1.1e-21 77.8 0.0 2.2 2 0 0 2 2 2 2 FtsJ-like methyltransferase G-patch PF01585.23 PRP78494.1 - 1.9e-12 46.8 2.5 6.3e-12 45.2 2.5 2.0 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PRP78494.1 - 0.00014 21.9 3.2 0.00032 20.7 3.2 1.6 1 0 0 1 1 1 1 G-patch domain Pox_mRNA-cap PF03341.13 PRP78494.1 - 0.089 12.1 0.4 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Poxvirus mRNA capping enzyme, small subunit LRR_6 PF13516.6 PRP78495.1 - 1.6e-11 43.3 15.4 0.0013 18.6 0.1 5.7 6 0 0 6 6 6 3 Leucine Rich repeat Ank_5 PF13857.6 PRP78495.1 - 4.9e-08 33.1 0.1 2.7e-07 30.7 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP78495.1 - 1.7e-05 25.3 0.2 7.6e-05 23.2 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP78495.1 - 3.9e-05 23.7 0.1 0.00058 20.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat LRR_8 PF13855.6 PRP78495.1 - 0.001 18.8 6.8 1.3 8.8 1.0 4.4 2 2 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PRP78495.1 - 0.0012 19.2 7.8 0.23 11.9 1.1 3.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Ank PF00023.30 PRP78495.1 - 0.0034 17.8 0.3 0.018 15.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 PRP78495.1 - 0.016 15.7 0.4 0.41 11.3 0.1 2.6 2 1 0 3 3 3 0 Ankyrin repeats (many copies) LRR_1 PF00560.33 PRP78495.1 - 5.4 8.0 6.2 67 4.6 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat CPSF73-100_C PF11718.8 PRP78496.1 - 1e-30 106.9 3.0 2.6e-28 99.1 3.0 2.4 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 PRP78496.1 - 2.1e-27 95.6 0.0 5e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 PRP78496.1 - 1.3e-10 41.1 0.0 4.5e-10 39.3 0.0 1.9 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 PRP78496.1 - 0.00017 21.4 0.0 0.00042 20.2 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta_lactamase3 PF17030.5 PRP78496.1 - 0.022 14.0 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative beta-lactamase-like family Lactamase_B PF00753.27 PRP78496.1 - 0.035 14.1 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DRMBL PF07522.14 PRP78496.1 - 0.083 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Lactamase_B_3 PF13483.6 PRP78496.1 - 0.11 12.4 0.0 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Pkinase PF00069.25 PRP78497.1 - 3.6e-57 193.7 0.1 8.2e-56 189.3 0.1 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78497.1 - 2.8e-43 148.1 0.0 4.8e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RasGAP PF00616.19 PRP78497.1 - 1.1e-15 58.0 0.0 1.2e-14 54.5 0.0 2.2 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PSI PF01437.25 PRP78497.1 - 7.4e-07 29.6 46.1 0.0003 21.3 6.0 4.0 4 0 0 4 4 4 3 Plexin repeat DUF3543 PF12063.8 PRP78497.1 - 4.6e-05 22.9 0.1 0.00019 20.9 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Kdo PF06293.14 PRP78497.1 - 0.0027 17.1 0.0 0.0067 15.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP78497.1 - 0.0035 16.2 0.0 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase MIT PF04212.18 PRP78497.1 - 0.0097 16.0 10.0 0.041 13.9 0.3 3.2 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain APH PF01636.23 PRP78497.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3827 PF12877.7 PRP78497.1 - 0.15 10.4 0.3 0.33 9.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pkinase PF00069.25 PRP78499.1 - 2.5e-09 36.9 0.0 5.6e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP78499.1 - 2.4e-07 29.9 0.0 3.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PRP78499.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sulfatase PF00884.23 PRP78499.1 - 0.0047 16.4 0.1 0.015 14.7 0.1 1.8 1 1 0 1 1 1 1 Sulfatase Choline_kinase PF01633.20 PRP78499.1 - 0.097 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Retrotran_gag_2 PF14223.6 PRP78500.1 - 3.4e-05 23.5 1.3 0.32 10.7 0.2 3.0 2 1 0 2 2 2 2 gag-polypeptide of LTR copia-type DehI PF10778.9 PRP78500.1 - 0.022 14.9 0.0 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI Thioredoxin_4 PF13462.6 PRP78500.1 - 0.053 13.7 3.5 3.4 7.8 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin TNFR_c6 PF00020.18 PRP78500.1 - 0.62 10.5 8.5 17 5.9 0.2 4.0 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region AIM3 PF17096.5 PRP78500.1 - 2.1 9.3 5.3 53 4.9 1.2 3.4 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 3 RecQ_Zn_bind PF16124.5 PRP78500.1 - 3 8.7 8.6 53 4.6 0.1 4.7 4 0 0 4 4 4 0 RecQ zinc-binding zf-CXXC PF02008.20 PRP78500.1 - 3 7.9 12.5 6 7.0 1.0 3.9 3 0 0 3 3 3 0 CXXC zinc finger domain NADH_4Fe-4S PF10589.9 PRP78500.1 - 5.9 7.0 9.1 12 6.1 0.2 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region HJURP_mid PF12346.8 PRP78502.1 - 0.0029 18.1 0.1 0.0036 17.8 0.1 1.2 1 0 0 1 1 1 1 Holliday junction recognition protein-associated repeat SAM_1 PF00536.30 PRP78503.1 - 0.012 16.1 0.2 0.027 14.9 0.2 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP78503.1 - 0.16 12.1 0.1 0.45 10.7 0.1 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SatRNA_48 PF17485.2 PRP78504.1 - 0.16 11.1 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Satellite RNA 48 kDa protein GDPD PF03009.17 PRP78505.1 - 1.7e-58 198.4 0.1 3.7e-58 197.3 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 PRP78505.1 - 9.2e-15 54.3 0.1 2.6e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain PrpR_N PF06506.11 PRP78505.1 - 0.0011 18.6 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 Propionate catabolism activator MBOAT_2 PF13813.6 PRP78506.1 - 0.14 12.4 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family zf-C3HC4 PF00097.25 PRP78506.1 - 0.29 11.0 7.9 0.93 9.4 7.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FSAP_sig_propep PF03032.15 PRP78506.1 - 1.3 9.1 7.1 3.4 7.8 7.1 1.7 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide B12-binding PF02310.19 PRP78507.1 - 0.0088 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 B12 binding domain Pkinase_Tyr PF07714.17 PRP78508.1 - 5.4e-67 225.8 0.0 8.1e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78508.1 - 6e-43 147.1 0.0 1e-42 146.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP78508.1 - 2e-05 24.1 0.0 4.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP78508.1 - 0.081 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TMEM154 PF15102.6 PRP78508.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Sugar_tr PF00083.24 PRP78509.1 - 1e-85 288.4 26.0 1.3e-85 288.0 26.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP78509.1 - 1.4e-21 76.9 45.1 8.1e-18 64.5 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LysM PF01476.20 PRP78509.1 - 0.0073 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 LysM domain Ssu72 PF04722.13 PRP78511.1 - 4.2e-63 212.4 0.0 4.7e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein PriC PF07445.12 PRP78511.1 - 0.013 15.4 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC ZapB PF06005.12 PRP78511.1 - 0.014 15.9 1.4 4.5 7.8 0.8 2.3 2 0 0 2 2 2 0 Cell division protein ZapB zf-LITAF-like PF10601.9 PRP78512.1 - 2.5e-21 75.7 14.0 3.4e-21 75.3 14.0 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Ion_trans PF00520.31 PRP78513.1 - 1.3e-33 116.2 57.9 1.2e-19 70.5 21.9 2.2 2 0 0 2 2 2 2 Ion transport protein Adipogenin PF15202.6 PRP78513.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.9 3 0 0 3 3 3 0 Adipogenin Asparaginase PF00710.20 PRP78514.1 - 3.3e-52 176.8 0.0 5.7e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 PRP78514.1 - 3.3e-28 98.2 0.1 5.1e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain ABC_tran PF00005.27 PRP78516.1 - 1.6e-25 90.3 0.1 3.5e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PRP78516.1 - 0.0011 19.0 0.1 0.0033 17.4 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 PRP78516.1 - 0.0013 18.7 0.0 0.49 10.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 PRP78516.1 - 0.0048 16.8 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 PRP78516.1 - 0.022 15.1 0.0 0.076 13.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 PRP78516.1 - 0.026 14.1 0.2 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 PRP78516.1 - 0.055 13.1 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 PRP78516.1 - 0.057 13.9 0.5 0.37 11.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 PRP78516.1 - 0.067 12.9 0.5 0.18 11.6 0.5 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP78516.1 - 1.2 9.5 5.7 0.6 10.6 0.4 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 PRP78516.1 - 4.1 6.4 10.1 12 4.9 10.1 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein Adenylsucc_synt PF00709.21 PRP78517.1 - 5.7e-170 565.8 0.0 6.8e-170 565.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF2547 PF10818.8 PRP78518.1 - 0.0073 17.2 0.0 16 6.5 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2547) ANAPC2 PF08672.11 PRP78518.1 - 0.01 16.3 5.2 4.6 7.8 0.1 3.6 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 RRM_5 PF13893.6 PRP78518.1 - 0.34 10.5 2.5 52 3.5 0.0 4.0 5 0 0 5 5 5 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDUF_B7 PF05676.13 PRP78518.1 - 1.3 8.8 2.9 1.1e+02 2.6 0.1 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PA14 PF07691.12 PRP78519.1 - 0.0038 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain RTC PF01137.21 PRP78520.1 - 9.7e-51 172.1 0.0 1.2e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 PRP78520.1 - 6.3e-32 110.2 0.0 1.2e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Ig_2 PF13895.6 PRP78520.1 - 0.072 13.4 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain TPR_12 PF13424.6 PRP78521.1 - 1e-08 35.3 5.8 0.034 14.4 0.7 6.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP78521.1 - 0.003 17.5 0.3 4.1 7.7 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP78521.1 - 0.015 14.7 0.1 0.8 9.0 0.0 3.3 4 0 0 4 4 4 0 MalT-like TPR region TPR_6 PF13174.6 PRP78521.1 - 0.016 15.8 0.3 11 6.9 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 PRP78521.1 - 0.028 13.9 3.4 1.7 8.0 0.2 2.9 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP FliS PF02561.14 PRP78521.1 - 0.1 12.9 0.3 2.1 8.6 0.1 3.0 2 0 0 2 2 2 0 Flagellar protein FliS ANAPC5 PF12862.7 PRP78521.1 - 0.15 12.2 9.1 0.15 12.1 0.1 4.2 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 SMBP PF16785.5 PRP78521.1 - 0.54 10.5 3.6 4.8 7.4 3.6 2.3 1 1 0 1 1 1 0 Small metal-binding protein TPR_8 PF13181.6 PRP78521.1 - 2.3 8.7 12.0 35 4.9 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 PRP78522.1 - 5.1e-44 150.6 0.0 7e-43 146.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78522.1 - 9.3e-14 51.3 0.0 1.5e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP78522.1 - 9e-06 25.2 0.0 2.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP78522.1 - 3.6e-05 23.2 0.1 8.1e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP78522.1 - 0.0002 21.4 0.0 0.098 12.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family ERAP1_C PF11838.8 PRP78523.1 - 2.9e-83 280.0 1.4 2.8e-82 276.8 0.5 2.4 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 PRP78523.1 - 4.7e-80 268.3 1.9 7.4e-80 267.6 1.9 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PRP78523.1 - 2.6e-55 187.5 0.5 4.5e-55 186.7 0.5 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 PRP78523.1 - 0.0085 16.2 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF45 DUF2808 PF10989.8 PRP78523.1 - 0.061 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) TrbL PF04610.14 PRP78523.1 - 0.095 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MFS_1 PF07690.16 PRP78524.1 - 4.6e-28 98.1 31.2 2e-17 63.2 16.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP78524.1 - 1.4e-26 93.4 30.3 1.9e-25 89.6 30.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Dynamin_N PF00350.23 PRP78525.1 - 2.6e-19 69.9 0.3 1.3e-18 67.7 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PRP78525.1 - 0.00016 21.7 0.3 0.00071 19.6 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP78525.1 - 0.0051 16.7 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase SWIB PF02201.18 PRP78526.1 - 3.1e-25 87.8 0.1 5.7e-25 87.0 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 PRP78526.1 - 2.4e-06 27.3 0.6 8.4e-06 25.6 0.3 2.1 2 0 0 2 2 2 1 DEK C terminal domain CCDC106 PF15794.5 PRP78526.1 - 0.31 10.7 13.4 0.62 9.7 13.3 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 SRP-alpha_N PF04086.13 PRP78526.1 - 1.4 8.7 21.3 2.3 8.1 21.3 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4661 PF15576.6 PRP78526.1 - 3.5 7.5 7.6 5.1 6.9 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) V_ATPase_I PF01496.19 PRP78526.1 - 4.4 5.1 5.5 6.2 4.6 5.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GIDE PF12483.8 PRP78527.1 - 2.6e-11 43.2 0.0 9.7e-11 41.3 0.0 1.9 1 1 1 2 2 2 1 E3 Ubiquitin ligase G8 PF10162.9 PRP78528.1 - 0.0014 18.7 6.2 0.016 15.3 1.1 4.0 2 2 1 3 3 3 1 G8 domain Amnionless PF14828.6 PRP78528.1 - 0.07 12.0 0.1 0.07 12.0 0.1 1.7 2 0 0 2 2 2 0 Amnionless RhoGEF PF00621.20 PRP78529.1 - 5.8e-38 130.9 0.4 5.8e-38 130.9 0.4 1.9 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 PRP78529.1 - 6.9e-19 67.8 13.7 1.4e-18 66.8 13.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 PRP78529.1 - 4.1e-11 43.3 0.4 1.3e-10 41.7 0.4 2.0 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 PRP78529.1 - 1.4e-08 34.7 0.8 3.3e-08 33.5 0.8 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.28 PRP78529.1 - 7.5e-08 31.9 0.1 2.1e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP78529.1 - 1.6e-05 24.6 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_16 PF17838.1 PRP78529.1 - 0.0022 17.8 0.7 0.007 16.2 0.2 2.1 2 1 0 2 2 2 1 PH domain SH3_2 PF07653.17 PRP78529.1 - 0.012 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Siva PF05458.12 PRP78529.1 - 0.02 14.6 5.8 0.034 13.8 5.8 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF1835 PF08874.10 PRP78529.1 - 0.025 14.8 0.6 0.5 10.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) Mcp5_PH PF12814.7 PRP78529.1 - 0.026 14.6 1.0 0.094 12.8 1.0 2.1 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Mpv17_PMP22 PF04117.12 PRP78530.1 - 7.5e-24 83.7 2.3 1.3e-23 82.9 2.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family OSK PF17182.4 PRP78530.1 - 0.14 11.3 0.0 0.38 10.0 0.0 1.7 1 1 1 2 2 2 0 OSK domain Ank_4 PF13637.6 PRP78531.1 - 7.8e-12 45.5 1.8 0.0024 18.4 0.0 6.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) RRM_1 PF00076.22 PRP78531.1 - 1.5e-07 31.1 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 PRP78531.1 - 7.9e-07 29.6 0.0 0.0086 16.7 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP78531.1 - 1.6e-05 24.9 0.3 18 6.3 0.0 6.3 5 1 2 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 PRP78531.1 - 0.00062 20.0 1.0 0.098 13.0 0.0 4.7 5 2 1 7 7 7 1 Ankyrin repeats (many copies) Kin17_mid PF10357.9 PRP78532.1 - 1.1e-43 148.1 0.7 1.1e-43 148.1 0.7 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 PRP78532.1 - 1.4e-21 76.3 8.1 3.4e-21 75.1 8.1 1.7 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain DUF2470 PF10615.9 PRP78532.1 - 0.019 15.6 0.2 0.05 14.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) NdhS PF11623.8 PRP78532.1 - 0.03 14.0 0.4 1.5 8.5 0.2 2.4 2 0 0 2 2 2 0 NAD(P)H dehydrogenase subunit S zf-C2H2_jaz PF12171.8 PRP78532.1 - 0.033 14.5 5.0 0.068 13.5 5.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PRP78532.1 - 0.054 13.8 0.9 0.054 13.8 0.9 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PRP78532.1 - 0.12 12.8 5.9 0.25 11.8 5.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF629 PF04780.12 PRP78532.1 - 0.23 10.0 8.5 0.43 9.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-RING_2 PF13639.6 PRP78533.1 - 4.6e-12 46.1 7.7 7.5e-12 45.4 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP78533.1 - 4.2e-09 36.1 6.1 7.5e-09 35.3 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP78533.1 - 4.7e-09 35.8 3.3 4.7e-09 35.8 3.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 PRP78533.1 - 9.8e-08 31.8 5.5 1.8e-07 30.9 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP78533.1 - 5.7e-07 29.7 7.0 1.4e-06 28.5 7.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PRP78533.1 - 1.4e-06 28.0 5.7 2.1e-06 27.5 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP78533.1 - 3.2e-06 27.1 3.0 6.5e-06 26.1 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP78533.1 - 6.3e-06 26.1 5.3 1e-05 25.4 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PRP78533.1 - 0.00041 20.1 6.6 0.00072 19.4 6.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PRP78533.1 - 0.0082 16.2 1.8 0.015 15.3 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PRP78533.1 - 0.031 13.9 6.2 0.052 13.2 6.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 PRP78533.1 - 0.068 13.5 5.2 0.15 12.4 5.1 1.7 1 1 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 PRP78533.1 - 1.2 9.1 5.7 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Vps39_2 PF10367.9 PRP78533.1 - 2.3 8.7 5.8 17 5.9 0.1 2.9 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Acyl_transf_1 PF00698.21 PRP78534.1 - 9.6e-28 97.6 0.2 1.4e-27 97.1 0.2 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 PRP78534.1 - 0.046 13.4 0.4 0.88 9.3 0.4 2.3 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis GSAP-16 PF14959.6 PRP78535.1 - 2.5e-18 65.9 0.0 7.3e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term HupH_C PF04809.13 PRP78537.1 - 0.049 13.3 0.1 0.057 13.1 0.1 1.1 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region Rogdi_lz PF10259.9 PRP78538.1 - 2.9e-13 49.9 0.0 3.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein IL3 PF02059.15 PRP78538.1 - 0.021 14.8 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Interleukin-3 GST_N PF02798.20 PRP78540.1 - 2.1e-13 50.4 0.0 3.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP78540.1 - 5.4e-08 33.1 0.0 8.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP78540.1 - 9e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP78540.1 - 0.0022 18.1 0.1 0.0042 17.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 PRP78540.1 - 0.035 14.4 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein RicinB_lectin_2 PF14200.6 PRP78541.1 - 2.9e-07 31.1 1.0 0.00037 21.2 0.0 4.1 4 1 2 6 6 6 3 Ricin-type beta-trefoil lectin domain-like B_lectin PF01453.24 PRP78541.1 - 5.9e-05 23.6 0.4 0.013 16.1 0.0 2.9 2 1 1 3 3 3 2 D-mannose binding lectin Diedel PF13164.6 PRP78541.1 - 0.056 13.9 0.7 0.19 12.2 0.3 2.1 2 0 0 2 2 2 0 Diedel Peptidase_M90 PF06167.12 PRP78541.1 - 0.13 11.8 0.4 0.36 10.4 0.3 1.8 1 1 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 MAD PF05557.13 PRP78542.1 - 0.016 13.6 0.1 0.02 13.3 0.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Shugoshin_N PF07558.11 PRP78542.1 - 0.031 14.2 0.2 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF5105 PF17118.5 PRP78542.1 - 0.036 13.8 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5105) BCAS2 PF05700.11 PRP78542.1 - 0.036 13.7 0.1 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Mus7 PF09462.10 PRP78542.1 - 0.048 12.5 0.1 0.054 12.4 0.1 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family FapA PF03961.13 PRP78542.1 - 0.062 11.9 0.0 0.071 11.7 0.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A TSC22 PF01166.18 PRP78542.1 - 0.062 13.6 0.9 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family BRI3BP PF14965.6 PRP78542.1 - 0.072 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 T2SSM PF04612.12 PRP78542.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M JIP_LZII PF16471.5 PRP78542.1 - 0.14 12.4 0.7 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 PRP78542.1 - 0.17 12.0 0.4 0.69 10.1 0.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor Nop14 PF04147.12 PRP78544.1 - 3.4 5.8 54.9 6.1 4.9 54.9 1.4 1 0 0 1 1 1 0 Nop14-like family GST_N_3 PF13417.6 PRP78545.1 - 1.3e-09 38.3 0.0 6.2e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP78545.1 - 2.9e-08 33.6 0.2 9.9e-08 31.9 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP78545.1 - 3.4e-07 30.5 0.0 1.5e-06 28.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP78545.1 - 1.1e-05 25.5 0.1 2.1e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PRP78545.1 - 2e-05 24.8 0.0 6.7e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP78545.1 - 0.00052 20.2 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNA_pol_N PF01194.17 PRP78546.1 - 8.4e-32 109.3 0.5 9.6e-32 109.1 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 PRP78546.1 - 0.027 14.7 0.5 0.043 14.1 0.5 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Arf PF00025.21 PRP78547.1 - 1.6e-67 226.3 0.5 1.9e-67 226.1 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PRP78547.1 - 6.7e-13 48.9 0.0 9.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PRP78547.1 - 2.7e-12 46.5 2.2 8.2e-07 28.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PRP78547.1 - 2.2e-09 37.0 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PRP78547.1 - 2.5e-09 37.0 0.0 3.2e-09 36.6 0.0 1.2 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 PRP78547.1 - 4.3e-07 29.5 0.0 5.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP78547.1 - 6.1e-07 29.5 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP78547.1 - 0.00019 21.0 0.0 0.0015 18.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PRP78547.1 - 0.00024 20.7 0.1 0.0021 17.6 0.1 2.3 1 1 0 2 2 2 1 Ferrous iron transport protein B NST1 PF13945.6 PRP78548.1 - 5.6e-53 179.9 4.4 5.6e-53 179.9 4.4 4.9 5 0 0 5 5 5 3 Salt tolerance down-regulator HAUS6_N PF14661.6 PRP78550.1 - 1.5e-22 80.4 0.3 1.5e-22 80.4 0.3 9.7 3 1 6 9 9 9 1 HAUS augmin-like complex subunit 6 N-terminus Ank_2 PF12796.7 PRP78550.1 - 9.5e-19 67.8 4.0 8.9e-12 45.4 0.4 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78550.1 - 1.2e-11 44.8 0.8 7.5e-06 26.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP78550.1 - 5.8e-11 42.4 0.2 0.00063 20.0 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP78550.1 - 1.4e-09 37.9 1.6 7e-05 23.1 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP78550.1 - 7.3e-07 29.0 0.8 0.0048 17.3 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeat G6PD_C PF02781.16 PRP78551.1 - 1.8e-93 312.9 0.0 2.4e-93 312.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PRP78551.1 - 3.2e-38 132.1 0.0 6.6e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Ank_2 PF12796.7 PRP78552.1 - 1.1e-54 182.9 11.6 1.5e-16 60.7 0.2 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 PRP78552.1 - 7.9e-37 124.1 4.1 9.4e-06 25.8 0.0 6.5 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.6 PRP78552.1 - 1.7e-32 111.3 0.1 1.2e-07 32.1 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78552.1 - 9.8e-30 99.3 0.0 4.5e-05 23.5 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 PRP78552.1 - 9.2e-29 99.1 0.2 3.1e-09 36.9 0.1 5.0 3 1 1 5 5 5 4 Ankyrin repeats (many copies) HEAT PF02985.22 PRP78553.1 - 4.5e-28 94.9 12.3 0.041 14.1 0.0 13.0 14 0 0 14 14 13 6 HEAT repeat HEAT_2 PF13646.6 PRP78553.1 - 1.1e-17 64.2 0.0 0.0013 19.1 0.0 8.3 5 2 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 PRP78553.1 - 2.5e-15 56.6 4.1 0.63 10.6 0.1 9.5 9 2 1 10 10 9 3 HEAT-like repeat Cnd1 PF12717.7 PRP78553.1 - 6.9e-12 45.7 1.7 0.021 14.9 0.0 6.1 4 2 3 8 8 7 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 PRP78553.1 - 1.9e-11 43.7 1.3 2.6e-09 36.8 0.1 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 PRP78553.1 - 2.6e-09 37.6 4.6 3.9 8.1 0.0 8.4 8 3 3 11 11 10 2 Vacuolar 14 Fab1-binding region UME PF08064.13 PRP78553.1 - 1.2e-06 28.4 0.2 1.2 9.1 0.0 5.7 5 1 1 6 6 5 2 UME (NUC010) domain Ipi1_N PF12333.8 PRP78553.1 - 2.9e-06 27.8 0.2 0.0077 16.8 0.1 4.5 4 1 1 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.8 PRP78553.1 - 7e-06 25.8 0.1 5.5 6.5 0.0 5.5 5 2 2 7 7 7 1 CLASP N terminal IFRD PF05004.13 PRP78553.1 - 7.8e-06 25.2 3.4 0.31 10.1 0.2 4.9 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) MMS19_N PF14500.6 PRP78553.1 - 1.7e-05 24.6 0.0 17 4.9 0.0 6.0 5 2 1 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II ParcG PF10274.9 PRP78553.1 - 7e-05 23.0 0.0 0.45 10.6 0.0 4.6 3 1 2 5 5 5 1 Parkin co-regulated protein DUF4042 PF13251.6 PRP78553.1 - 0.00017 21.3 0.1 16 5.1 0.1 4.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4042) DUF577 PF04510.12 PRP78553.1 - 0.00024 21.0 0.1 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF577) MMS19_C PF12460.8 PRP78553.1 - 0.00036 19.8 0.6 2 7.4 0.1 4.7 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal DRIM PF07539.12 PRP78553.1 - 0.0093 14.3 0.3 0.4 8.9 0.0 3.4 2 2 1 3 3 3 1 Down-regulated in metastasis Nipped-B_C PF12830.7 PRP78553.1 - 0.023 14.7 0.0 2.8 7.8 0.0 3.8 2 2 0 3 3 3 0 Sister chromatid cohesion C-terminus UNC45-central PF11701.8 PRP78553.1 - 0.024 14.6 0.4 20 5.1 0.0 4.2 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central BAF250_C PF12031.8 PRP78553.1 - 0.048 13.0 0.1 0.78 9.0 0.0 2.9 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa RasGEF_N_2 PF14663.6 PRP78553.1 - 0.27 11.6 1.3 36 4.8 0.0 4.5 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain UPF0149 PF03695.13 PRP78553.1 - 0.33 11.2 2.2 18 5.5 0.3 3.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0149) LRRNT_2 PF08263.12 PRP78554.1 - 0.12 12.7 2.9 0.22 11.8 2.9 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Hydrolase_4 PF12146.8 PRP78555.1 - 9.4e-05 21.8 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP78555.1 - 0.00043 20.0 0.4 0.00089 19.0 0.4 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 PRP78555.1 - 0.0082 15.2 0.1 0.018 14.1 0.1 1.6 1 1 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 PRP78555.1 - 0.073 12.7 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 PRP78555.1 - 0.23 12.0 0.0 0.3 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cpn60_TCP1 PF00118.24 PRP78556.1 - 4e-167 556.7 5.4 5e-167 556.4 5.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GCD14 PF08704.10 PRP78558.1 - 4.4e-74 249.3 0.5 4.4e-74 249.3 0.5 3.4 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Pro_isomerase PF00160.21 PRP78558.1 - 7.3e-45 153.1 0.0 7.3e-45 153.1 0.0 2.1 3 0 0 3 3 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Y_phosphatase3 PF13350.6 PRP78558.1 - 9.3e-31 107.6 0.0 9.5e-29 101.0 0.0 2.3 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 PRP78558.1 - 4.6e-06 26.3 0.0 1.5e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family SR-25 PF10500.9 PRP78558.1 - 5.5e-06 26.2 30.2 5.5e-06 26.2 30.2 3.9 4 0 0 4 4 3 1 Nuclear RNA-splicing-associated protein GCD14_N PF14801.6 PRP78558.1 - 0.00046 20.0 0.1 0.00098 18.9 0.1 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term CAF-1_p150 PF11600.8 PRP78558.1 - 0.00089 19.0 5.7 0.00089 19.0 5.7 3.3 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Methyltransf_31 PF13847.6 PRP78558.1 - 0.002 17.9 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DSPc PF00782.20 PRP78558.1 - 0.0037 17.1 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain IMUP PF15761.5 PRP78558.1 - 0.0045 17.7 24.2 0.0045 17.7 24.2 3.1 4 0 0 4 4 2 1 Immortalisation up-regulated protein Y_phosphatase PF00102.27 PRP78558.1 - 0.0054 16.3 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PCMT PF01135.19 PRP78558.1 - 0.02 14.7 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Myotub-related PF06602.14 PRP78558.1 - 0.062 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DDHD PF02862.17 PRP78558.1 - 7.3 6.7 13.9 2.9 8.0 5.4 2.4 2 0 0 2 2 2 0 DDHD domain Sedlin_N PF04628.13 PRP78559.1 - 1.9e-41 141.2 2.3 4e-41 140.2 2.3 1.5 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 PRP78559.1 - 7.3e-09 35.7 0.9 1.9e-08 34.3 0.9 1.7 1 1 0 1 1 1 1 Sybindin-like family FrpC PF06901.12 PRP78559.1 - 0.013 15.1 0.2 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC Cytochrom_C PF00034.21 PRP78560.1 - 1e-11 45.8 0.0 1.4e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 PRP78560.1 - 1e-06 28.9 1.3 5e-06 26.7 1.3 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 PRP78560.1 - 0.0028 17.3 0.2 0.032 13.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 PRP78560.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 LCAT PF02450.15 PRP78561.1 - 1.8e-38 132.7 0.8 2.4e-29 102.7 0.1 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase HA PF03457.14 PRP78562.1 - 0.0017 18.7 0.8 0.0019 18.5 0.2 1.4 2 0 0 2 2 2 1 Helicase associated domain MCD_N PF17408.2 PRP78562.1 - 0.0025 17.9 0.4 0.0037 17.4 0.0 1.6 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase N-terminal domain ELK PF03789.13 PRP78562.1 - 0.038 14.1 0.1 9.8 6.4 0.0 3.4 3 0 0 3 3 3 0 ELK domain Pneumo_M2 PF07380.11 PRP78562.1 - 0.23 11.7 3.0 0.27 11.6 2.5 1.5 1 1 0 1 1 1 0 Pneumovirus M2 protein rve PF00665.26 PRP78563.1 - 6.3e-08 32.8 0.0 0.0031 17.7 0.0 2.3 1 1 1 2 2 2 2 Integrase core domain S_100 PF01023.19 PRP78563.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.0 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain Dynamin_M PF01031.20 PRP78564.1 - 0.035 13.3 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Dynamin central region ATP-synt_F6 PF05511.11 PRP78565.1 - 1.3 9.5 6.4 1.2 9.6 4.5 2.1 2 1 0 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF4746 PF15928.5 PRP78569.1 - 0.88 8.9 13.9 1.5 8.2 13.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2201_N PF13203.6 PRP78569.1 - 1.5 8.4 7.0 0.39 10.3 4.1 1.5 2 0 0 2 2 2 0 Putative metallopeptidase domain CDC45 PF02724.14 PRP78569.1 - 2.4 6.4 12.9 3.1 6.0 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Mo25 PF08569.11 PRP78570.1 - 2.7e-124 414.8 4.0 3.2e-124 414.6 4.0 1.0 1 0 0 1 1 1 1 Mo25-like Hydrolase PF00702.26 PRP78571.1 - 4.6e-08 33.6 0.0 0.008 16.5 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PRP78571.1 - 5.2e-06 26.1 0.7 7.3e-05 22.4 0.0 2.9 2 0 0 2 2 2 1 E1-E2 ATPase IF3_N PF05198.16 PRP78572.1 - 5.2e-12 45.9 0.1 1.1e-11 44.8 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 PRP78572.1 - 1.2e-10 41.2 0.1 3.8e-10 39.6 0.1 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Glucosamine_iso PF01182.20 PRP78573.1 - 3.7e-23 82.6 0.0 4.7e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sec15 PF04091.12 PRP78574.1 - 7.5e-41 140.5 7.8 7.5e-41 140.5 7.8 2.6 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 PRP78574.1 - 2.2e-08 34.0 0.2 2.7e-06 27.4 0.2 3.2 1 1 1 2 2 2 2 Vps51/Vps67 COG2 PF06148.11 PRP78574.1 - 0.0097 16.0 1.7 0.49 10.5 0.2 3.7 2 1 1 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 RNA_polI_A14 PF08203.11 PRP78574.1 - 2 9.2 5.0 22 5.9 0.3 3.5 2 1 1 3 3 3 0 Yeast RNA polymerase I subunit RPA14 Cys_Met_Meta_PP PF01053.20 PRP78575.1 - 2.1e-128 428.1 0.0 2.5e-128 427.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 PRP78575.1 - 0.00075 18.1 0.0 0.0048 15.5 0.0 1.9 2 0 0 2 2 2 1 Methionine gamma-lyase SelA PF03841.13 PRP78575.1 - 0.0031 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 L-seryl-tRNA selenium transferase GDC-P PF02347.16 PRP78575.1 - 0.026 13.3 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Aminotran_5 PF00266.19 PRP78575.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V GDA1_CD39 PF01150.17 PRP78577.1 - 1e-15 57.4 0.2 1.1e-07 30.9 0.1 2.3 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family F5_F8_type_C PF00754.25 PRP78577.1 - 0.024 14.7 0.0 0.25 11.5 0.0 2.5 2 0 0 2 2 2 0 F5/8 type C domain CpXC PF14353.6 PRP78577.1 - 0.094 12.8 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 CpXC protein PSI PF01437.25 PRP78577.1 - 0.2 12.2 5.9 0.99 10.0 5.9 2.3 1 0 0 1 1 1 0 Plexin repeat Arm_3 PF16186.5 PRP78577.1 - 4.5 6.9 7.2 17 5.0 0.1 3.6 3 0 0 3 3 3 0 Atypical Arm repeat Pkinase_Tyr PF07714.17 PRP78578.1 - 2e-38 132.1 1.4 2.7e-24 85.9 0.1 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP78578.1 - 1.9e-22 79.9 0.3 2.6e-18 66.4 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain SKG6 PF08693.10 PRP78578.1 - 0.023 14.1 0.6 0.042 13.3 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HMG_box_5 PF14887.6 PRP78578.1 - 0.24 11.4 1.3 2 8.4 0.2 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box 5 HNH_2 PF13391.6 PRP78580.1 - 0.068 13.3 0.0 0.17 12.1 0.0 1.8 1 1 0 1 1 1 0 HNH endonuclease VHP PF02209.19 PRP78580.1 - 0.07 13.2 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 Villin headpiece domain GCFC PF07842.12 PRP78584.1 - 4.8e-15 55.9 0.5 3.4e-13 49.8 0.5 2.4 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein PMC2NT PF08066.12 PRP78584.1 - 0.81 10.4 3.8 1.2 9.8 0.4 3.2 1 1 2 3 3 3 0 PMC2NT (NUC016) domain RT_RNaseH PF17917.1 PRP78585.1 - 1.3e-05 25.4 0.1 2.8e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_RpbA PF10789.9 PRP78588.1 - 0.11 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA Churchill PF06573.11 PRP78591.1 - 1.8e-12 47.5 1.8 3.8e-12 46.5 1.8 1.6 1 1 0 1 1 1 1 Churchill protein PhnA_Zn_Ribbon PF08274.12 PRP78591.1 - 0.029 14.3 5.4 0.14 12.1 0.5 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon E7 PF00527.18 PRP78591.1 - 0.03 14.5 0.3 0.075 13.2 0.4 1.7 1 1 0 1 1 1 0 E7 protein, Early protein TF_Zn_Ribbon PF08271.12 PRP78591.1 - 0.39 10.3 3.6 1.3 8.6 3.6 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding UPF0547 PF10571.9 PRP78591.1 - 0.72 10.0 0.2 0.72 10.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CtaG_Cox11 PF04442.14 PRP78593.1 - 2.2e-60 203.1 0.1 2.9e-60 202.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Med21 PF11221.8 PRP78594.1 - 1.9e-16 60.6 11.4 5.9e-16 59.0 11.4 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 PRP78594.1 - 0.0036 17.4 8.0 0.0058 16.7 2.5 2.7 2 1 1 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 TPR_12 PF13424.6 PRP78595.1 - 7.3e-06 26.2 0.8 0.0059 16.9 0.3 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 PRP78595.1 - 1.7e-05 24.4 2.8 2.2e-05 24.0 1.3 1.9 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 PRP78595.1 - 0.0002 21.0 1.2 0.27 11.1 0.7 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP78595.1 - 0.00038 19.9 0.1 0.069 12.5 0.0 2.2 2 0 0 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 PRP78595.1 - 0.0007 19.5 4.0 0.051 13.7 1.1 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP78595.1 - 0.0042 16.9 0.2 6.5 6.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 PRP78595.1 - 0.02 14.6 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.6 PRP78595.1 - 0.025 14.8 1.4 0.31 11.4 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP78595.1 - 0.025 15.4 0.0 1.7 9.6 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 PRP78595.1 - 0.08 13.0 0.4 3.3 7.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat RP854 PF17460.2 PRP78595.1 - 0.13 12.0 3.2 0.84 9.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein RP854 TPR_7 PF13176.6 PRP78595.1 - 0.17 12.0 1.3 12 6.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat L27_N PF09060.10 PRP78595.1 - 0.81 9.8 2.9 17 5.6 0.1 3.7 4 0 0 4 4 4 0 L27_N Myosin_head PF00063.21 PRP78597.1 - 1.3e-230 767.2 0.2 2.1e-230 766.6 0.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 PRP78597.1 - 4.3e-07 29.1 12.1 0.00016 21.2 0.5 3.6 3 0 0 3 3 3 3 IQ calmodulin-binding motif AAA_16 PF13191.6 PRP78597.1 - 0.0082 16.5 0.1 0.034 14.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain K-box PF01486.17 PRP78597.1 - 0.016 15.4 0.0 0.016 15.4 0.0 2.4 2 1 0 2 2 2 0 K-box region AAA_6 PF12774.7 PRP78597.1 - 0.032 13.2 1.0 0.049 12.6 0.0 1.7 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 PRP78597.1 - 0.037 14.3 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PRP78597.1 - 0.088 13.3 0.0 0.36 11.4 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 PRP78597.1 - 0.13 12.6 0.1 0.94 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PRP78597.1 - 0.16 12.0 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 PRP78597.1 - 0.7 9.6 4.6 22 4.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_pol_Rbc25 PF08292.12 PRP78597.1 - 1.1 9.5 3.0 4.7 7.4 2.8 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Codanin-1_C PF15296.6 PRP78598.1 - 7.8e-06 26.0 0.2 0.00012 22.2 0.0 2.9 2 1 1 3 3 3 1 Codanin-1 C-terminus Auxin_canalis PF05703.11 PRP78598.1 - 0.22 11.4 4.2 0.14 12.1 0.7 2.3 2 0 0 2 2 2 0 Auxin canalisation Nbs1_C PF08599.10 PRP78598.1 - 4.3 7.6 5.5 0.91 9.7 0.9 2.4 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Ric8 PF10165.9 PRP78599.1 - 1.2e-30 107.0 0.0 1.4e-29 103.5 0.0 2.1 2 0 0 2 2 2 2 Guanine nucleotide exchange factor synembryn DUF4225 PF13988.6 PRP78600.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Pkinase_Tyr PF07714.17 PRP78601.1 - 1.4e-58 198.2 0.0 2.1e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78601.1 - 4.4e-42 144.3 0.0 6.8e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP78601.1 - 1e-38 130.8 73.1 8.3e-07 28.7 4.5 13.6 10 2 2 14 14 14 11 Leucine rich repeat LRR_4 PF12799.7 PRP78601.1 - 3.9e-37 125.6 82.8 5.7e-05 23.4 0.3 17.0 12 4 6 18 18 18 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP78601.1 - 2.8e-06 26.9 62.4 0.13 12.3 0.5 17.0 19 0 0 19 19 19 4 Leucine Rich repeat Kdo PF06293.14 PRP78601.1 - 0.00038 19.9 0.1 0.00094 18.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP78601.1 - 0.0015 17.9 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Amnionless PF14828.6 PRP78601.1 - 0.0075 15.1 0.2 0.013 14.3 0.2 1.3 1 0 0 1 1 1 1 Amnionless Pkinase_fungal PF17667.1 PRP78601.1 - 0.0075 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase LRRNT_2 PF08263.12 PRP78601.1 - 0.022 15.0 0.0 0.075 13.4 0.0 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PRP78601.1 - 0.032 14.8 60.3 3.1 8.7 0.8 18.9 18 4 0 18 18 16 0 Leucine Rich Repeat FAM194 PF14977.6 PRP78601.1 - 0.051 12.9 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 FAM194 protein Podoplanin PF05808.11 PRP78601.1 - 0.054 13.6 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 Podoplanin Stevor PF17410.2 PRP78601.1 - 0.061 12.9 0.2 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame VSP PF03302.13 PRP78601.1 - 0.08 11.8 1.9 0.13 11.1 1.9 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF347 PF03988.12 PRP78601.1 - 0.36 11.0 1.7 0.74 10.0 1.7 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Mis12 PF05859.12 PRP78602.1 - 1e-12 48.3 3.3 2.4e-12 47.1 3.3 1.8 1 1 0 1 1 1 1 Mis12 protein DUF3450 PF11932.8 PRP78602.1 - 0.00017 21.0 1.0 0.00029 20.2 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF3251 PF11622.8 PRP78602.1 - 0.012 15.3 0.4 0.021 14.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) GIT_CC PF16559.5 PRP78602.1 - 0.019 14.8 1.2 0.047 13.6 1.2 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CALCOCO1 PF07888.11 PRP78602.1 - 0.02 13.8 11.0 0.029 13.3 11.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.19 PRP78602.1 - 0.059 11.3 3.3 0.081 10.8 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 PRP78602.1 - 0.073 13.7 10.4 1.1 10.0 8.4 2.8 2 1 0 2 2 2 0 Initiation control protein YabA DASH_Dad3 PF08656.10 PRP78602.1 - 0.091 12.9 6.7 0.094 12.8 3.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4407 PF14362.6 PRP78602.1 - 0.11 11.8 1.9 0.15 11.4 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3552 PF12072.8 PRP78602.1 - 0.16 11.4 13.2 0.043 13.2 9.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Swi5 PF07061.11 PRP78602.1 - 0.16 12.1 5.6 0.51 10.4 5.6 1.8 1 0 0 1 1 1 0 Swi5 Spc7 PF08317.11 PRP78602.1 - 0.17 10.8 9.3 0.26 10.1 9.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Dam1 PF08653.10 PRP78602.1 - 0.22 11.4 2.1 0.71 9.7 1.0 2.3 1 1 1 2 2 2 0 DASH complex subunit Dam1 LMBR1 PF04791.16 PRP78602.1 - 0.73 8.7 2.0 0.76 8.6 2.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein 60KD_IMP PF02096.20 PRP78602.1 - 0.82 9.5 2.3 1.3 9.0 2.3 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein CENP-H PF05837.12 PRP78602.1 - 1.8 9.0 10.1 29 5.1 9.1 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 PRP78602.1 - 3.4 8.6 13.2 11 6.9 0.0 3.2 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF5082 PF16888.5 PRP78602.1 - 4.1 7.7 12.7 5.1 7.4 9.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Synaptobrevin PF00957.21 PRP78602.1 - 4.5 7.1 7.9 15 5.4 0.2 2.3 1 1 1 2 2 2 0 Synaptobrevin DUF1664 PF07889.12 PRP78602.1 - 5.9 7.0 6.3 4 7.5 3.4 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 PRP78602.1 - 6.7 6.8 12.3 5 7.2 10.8 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 PRP78603.1 - 1e-66 219.2 33.0 2.4e-09 37.6 0.2 9.1 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP78603.1 - 9.4e-30 102.8 6.2 5.7e-05 23.3 0.1 7.1 3 2 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP78603.1 - 4.3e-16 58.8 0.1 6.4e-05 22.1 0.0 5.6 3 2 4 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP78603.1 - 7.5e-12 45.5 0.0 0.00016 21.6 0.0 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 PRP78603.1 - 1.3e-11 44.9 0.0 2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.6 PRP78603.1 - 1.2e-09 38.0 1.8 0.0047 16.3 0.0 5.0 2 2 3 5 5 5 3 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 PRP78603.1 - 1.2e-07 31.4 2.4 1.9 8.5 0.1 5.0 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Nup160 PF11715.8 PRP78603.1 - 6.6e-07 28.4 7.0 0.16 10.6 0.1 5.5 2 1 4 7 7 7 3 Nucleoporin Nup120/160 WD40_like PF17005.5 PRP78603.1 - 0.0022 17.4 0.0 2.3 7.5 0.0 3.5 2 1 1 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 PRP78603.1 - 0.011 14.3 0.0 0.042 12.4 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain DPPIV_N PF00930.21 PRP78603.1 - 0.014 14.2 0.5 18 3.9 0.0 4.0 3 2 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 PRP78603.1 - 0.032 13.9 2.5 2.5 7.8 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.11 PRP78603.1 - 0.047 12.4 0.6 2.3 6.9 0.0 3.0 3 1 1 4 4 4 0 Nup133 N terminal like WWE PF02825.20 PRP78604.1 - 1.5e-14 54.4 1.5 3.4e-14 53.2 1.5 1.7 1 0 0 1 1 1 1 WWE domain UQ_con PF00179.26 PRP78604.1 - 3.6e-05 23.4 0.0 0.00018 21.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RhoGAP PF00620.27 PRP78605.1 - 2.4e-44 150.8 0.0 5.7e-44 149.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 PRP78605.1 - 1.1e-18 67.6 0.2 3.2e-09 37.3 0.1 2.6 2 0 0 2 2 2 2 PH domain SH3_1 PF00018.28 PRP78605.1 - 1e-08 34.7 0.0 2.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP78605.1 - 1.3e-08 34.6 0.0 2.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP78605.1 - 3.7e-07 29.7 0.0 8.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CCDC144C PF14915.6 PRP78605.1 - 0.036 13.2 0.9 0.089 11.9 0.9 1.6 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region PH_3 PF14593.6 PRP78605.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 PH domain DUF2207 PF09972.9 PRP78605.1 - 0.81 8.4 4.6 0.29 9.9 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) UPF0542 PF15086.6 PRP78605.1 - 8.9 6.3 5.9 9.7 6.2 0.2 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 OST3_OST6 PF04756.13 PRP78606.1 - 4.4e-11 42.7 0.3 5.4e-11 42.4 0.3 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family COesterase PF00135.28 PRP78607.1 - 2.8e-115 386.1 0.0 3.8e-115 385.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP78607.1 - 4.5e-12 46.3 0.2 1.1e-11 45.0 0.2 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP78607.1 - 0.00018 21.0 0.1 0.00033 20.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family VWA_3 PF13768.6 PRP78607.1 - 0.0011 18.9 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP78607.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain K_trans PF02705.16 PRP78612.1 - 2e-97 326.9 15.0 2e-97 326.9 15.0 2.0 3 0 0 3 3 3 1 K+ potassium transporter Pkinase_Tyr PF07714.17 PRP78612.1 - 1.2e-61 208.3 1.0 4e-61 206.5 1.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78612.1 - 2.2e-46 158.4 0.5 8.1e-46 156.5 0.5 1.8 1 1 0 1 1 1 1 Protein kinase domain DUF4690 PF15756.5 PRP78612.1 - 0.00012 22.7 1.2 0.00064 20.3 0.0 2.8 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Haspin_kinase PF12330.8 PRP78612.1 - 0.0025 16.8 1.3 0.013 14.4 1.3 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP78612.1 - 0.065 12.0 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase Glyco_hydro_3_C PF01915.22 PRP78613.1 - 2.8e-59 200.5 0.0 2.2e-42 145.3 0.0 2.2 1 1 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PRP78613.1 - 1.6e-39 136.2 0.0 4.3e-39 134.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 PRP78613.1 - 3.1e-17 62.8 0.0 7.3e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 PRP78613.1 - 1.2e-13 51.0 0.3 2.8e-13 49.8 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain STAS PF01740.21 PRP78613.1 - 0.055 13.1 0.0 17 5.1 0.0 2.9 2 0 0 2 2 2 0 STAS domain UDG PF03167.19 PRP78613.1 - 0.13 12.3 0.0 25 4.8 0.0 2.6 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily Pkinase_Tyr PF07714.17 PRP78615.1 - 1.2e-46 159.1 0.0 1.8e-46 158.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78615.1 - 1.1e-42 146.2 0.0 1.9e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP78615.1 - 5.7e-08 32.7 0.1 1.8e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 PRP78615.1 - 9.2e-05 22.9 2.5 0.00021 21.8 2.5 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PRP78615.1 - 0.0091 16.3 2.2 0.024 14.9 2.2 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 PRP78615.1 - 0.027 13.3 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase ABC_tran PF00005.27 PRP78616.1 - 4.6e-25 88.7 0.0 7.1e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 PRP78616.1 - 1.2e-13 51.0 21.9 2.2e-13 50.1 21.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 PRP78616.1 - 5.3e-05 22.5 13.9 0.00011 21.5 13.9 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP78616.1 - 0.00014 21.8 0.1 0.025 14.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RecA PF00154.21 PRP78616.1 - 0.0011 18.5 0.2 0.0019 17.8 0.2 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_29 PF13555.6 PRP78616.1 - 0.0014 18.3 0.8 0.0031 17.2 0.8 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PRP78616.1 - 0.0022 17.9 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PRP78616.1 - 0.008 15.6 0.4 0.13 11.7 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PRP78616.1 - 0.01 16.3 0.2 0.019 15.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PRP78616.1 - 0.025 14.9 0.1 0.062 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PRP78616.1 - 0.036 14.4 0.0 0.069 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 PRP78616.1 - 0.043 13.4 0.1 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 PRP78616.1 - 0.058 12.7 0.4 0.09 12.1 0.4 1.2 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 PRP78616.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PRP78616.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 PRP78616.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PRP78616.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 PRP78616.1 - 0.22 12.0 0.1 0.63 10.5 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Acid_PPase PF12689.7 PRP78617.1 - 2.5e-33 115.3 0.0 5.8e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 PRP78617.1 - 0.076 12.8 0.0 0.54 10.0 0.0 2.3 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase UreE_C PF05194.12 PRP78618.1 - 0.14 12.7 7.0 0.19 12.2 7.0 1.2 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain UBA PF00627.31 PRP78619.1 - 3.8e-07 29.9 0.3 9e-07 28.7 0.3 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 PRP78619.1 - 0.096 12.5 0.5 0.27 11.1 0.5 1.8 1 0 0 1 1 1 0 UBA-like domain RuvA_C PF07499.13 PRP78619.1 - 0.21 12.1 0.0 0.42 11.1 0.0 1.4 1 0 0 1 1 1 0 RuvA, C-terminal domain CBM49 PF09478.10 PRP78620.1 - 2e-20 72.9 11.1 1.3e-17 63.8 2.5 3.1 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 GFO_IDH_MocA PF01408.22 PRP78620.1 - 6.8e-16 59.2 0.0 1.6e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PRP78620.1 - 2e-06 27.8 0.1 1e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Esterase_phd PF10503.9 PRP78620.1 - 0.0079 15.7 0.1 0.048 13.2 0.1 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 PRP78620.1 - 0.016 14.7 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Laminin_G_3 PF13385.6 PRP78621.1 - 7.2e-19 68.4 1.1 7.2e-19 68.4 1.1 2.3 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_17 PF00332.18 PRP78621.1 - 3.5e-14 53.1 2.4 1.8e-13 50.8 0.4 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Carb_bind PF10645.9 PRP78621.1 - 0.00016 21.8 16.9 0.0016 18.6 16.7 2.5 1 1 1 2 2 2 2 Carbohydrate binding SET PF00856.28 PRP78622.1 - 0.11 12.8 0.0 0.89 9.9 0.0 2.1 1 1 0 1 1 1 0 SET domain 5_nucleotid_C PF02872.18 PRP78623.1 - 1e-31 110.3 0.0 2.1e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PRP78623.1 - 5.3e-08 33.6 0.3 1.4e-07 32.2 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Actin PF00022.19 PRP78624.1 - 1.2e-82 277.7 0.0 7.2e-47 159.9 0.0 2.0 1 1 1 2 2 2 2 Actin Cauli_VI PF01693.16 PRP78624.1 - 0.2 12.0 0.6 44 4.5 0.1 3.0 3 0 0 3 3 3 0 Caulimovirus viroplasmin Nucleoporin_N PF08801.11 PRP78625.1 - 4.7e-06 25.6 0.0 9.2e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Nup133 N terminal like ANAPC3 PF12895.7 PRP78625.1 - 0.072 13.3 2.5 5 7.4 0.4 4.0 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Cyclin_N PF00134.23 PRP78626.1 - 1.2e-17 63.8 0.1 2.1e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP78626.1 - 1.1e-16 61.0 0.1 6.2e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Use1 PF09753.9 PRP78628.1 - 8.8e-28 97.7 11.9 1.2e-27 97.2 11.9 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Dsh_C PF12316.8 PRP78628.1 - 0.29 11.5 1.7 0.39 11.1 0.1 1.8 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal FAM60A PF15396.6 PRP78628.1 - 0.66 9.9 7.0 0.41 10.6 0.2 2.0 1 1 1 2 2 2 0 Protein Family FAM60A Zip PF02535.22 PRP78629.1 - 0.62 9.2 2.7 0.62 9.2 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AIF_C PF14721.6 PRP78629.1 - 2.1 8.7 5.9 3.9 7.8 5.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sortilin-Vps10 PF15902.5 PRP78631.1 - 1.1e-69 235.4 6.1 1.5e-69 234.9 6.1 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PRP78631.1 - 3.1e-27 96.0 5.6 5e-27 95.3 5.6 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PSII_BNR PF14870.6 PRP78631.1 - 0.00059 19.2 2.2 0.0042 16.4 2.2 2.3 1 1 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 PRP78631.1 - 0.012 15.5 28.6 5.2 7.5 0.9 7.5 7 0 0 7 7 7 0 BNR/Asp-box repeat DnaJ_CXXCXGXG PF00684.19 PRP78632.1 - 0.04 14.3 20.6 2.2 8.7 13.2 2.9 1 1 1 2 2 2 0 DnaJ central domain BAR PF03114.18 PRP78634.1 - 7.5e-21 74.9 10.1 1.2e-20 74.2 10.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 PRP78634.1 - 5.8e-10 38.6 0.1 9.3e-10 38.0 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP78634.1 - 2.6e-09 36.8 0.2 4.2e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP78634.1 - 1.6e-08 34.1 0.0 2.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 PRP78634.1 - 0.00065 19.3 5.5 0.00095 18.8 5.5 1.3 1 0 0 1 1 1 1 Arfaptin-like domain CREPT PF16566.5 PRP78634.1 - 1.8 8.8 6.9 3.7 7.7 0.6 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Vps16_C PF04840.12 PRP78635.1 - 8.3e-77 258.4 1.4 1.2e-76 257.8 1.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 PRP78635.1 - 1.5e-76 257.8 0.0 2.2e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region adh_short PF00106.25 PRP78636.1 - 2.8e-38 131.4 0.6 3.5e-38 131.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP78636.1 - 9e-22 77.8 0.3 1.2e-21 77.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP78636.1 - 1.3e-08 35.0 0.7 3.6e-08 33.5 0.7 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 PRP78636.1 - 0.024 14.9 0.2 0.061 13.6 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain CAP59_mtransfer PF11735.8 PRP78637.1 - 3.9e-51 174.1 0.0 4.9e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Pkinase_Tyr PF07714.17 PRP78638.1 - 3.3e-51 174.0 0.0 5.1e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78638.1 - 1.4e-39 136.0 0.0 2.4e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP78638.1 - 2.4e-21 75.4 57.9 0.0024 18.2 0.1 10.7 5 3 7 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP78638.1 - 3.7e-19 68.2 65.8 0.00023 20.9 5.1 9.4 2 2 13 15 15 15 13 Leucine rich repeat Pentapeptide_4 PF13599.6 PRP78638.1 - 0.03 14.5 3.3 1.5 9.0 1.0 4.2 3 1 0 3 3 3 0 Pentapeptide repeats (9 copies) Kdo PF06293.14 PRP78638.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 PRP78638.1 - 0.043 13.3 20.6 0.15 11.6 0.8 5.4 1 1 4 6 6 6 0 Leucine-rich repeat TMEM154 PF15102.6 PRP78638.1 - 0.055 13.4 0.2 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 TMEM154 protein family SHP PF03579.13 PRP78638.1 - 0.061 13.3 0.7 0.18 11.8 0.7 1.8 1 0 0 1 1 1 0 Small hydrophobic protein EphA2_TM PF14575.6 PRP78638.1 - 0.13 13.1 0.2 0.31 12.0 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Phage_1_1 PF08200.11 PRP78640.1 - 5 7.6 12.1 5.4 7.5 0.0 3.2 3 0 0 3 3 3 0 Bacteriophage 1.1 Protein S1 PF00575.23 PRP78641.1 - 2.7e-22 78.9 12.6 3.4e-08 33.7 0.0 11.8 10 2 0 10 10 10 3 S1 RNA binding domain Suf PF05843.14 PRP78641.1 - 1.6e-10 41.5 8.0 2.5e-05 24.4 0.6 5.2 4 1 1 5 5 5 3 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 PRP78641.1 - 3.2e-08 33.1 18.7 1e-06 28.1 1.9 3.6 2 2 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 PRP78641.1 - 7.6e-06 26.3 0.1 0.82 10.7 0.0 4.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP78641.1 - 3e-05 24.4 0.0 1.2 9.7 0.0 3.6 3 1 2 5 5 5 1 Tetratricopeptide repeat MRP-S35 PF10246.9 PRP78641.1 - 0.0035 17.3 0.1 7 6.7 0.0 3.6 3 0 0 3 3 3 1 Mitochondrial ribosomal protein MRP-S35 Utp13 PF08625.11 PRP78641.1 - 0.0081 16.1 0.3 0.02 14.8 0.3 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain TPR_15 PF13429.6 PRP78641.1 - 0.015 14.5 5.1 0.38 9.9 0.1 2.8 1 1 1 3 3 3 0 Tetratricopeptide repeat S1_2 PF13509.6 PRP78641.1 - 0.83 9.8 8.5 8.4 6.5 0.1 5.6 6 1 0 6 6 6 0 S1 domain Fer2_4 PF13510.6 PRP78642.1 - 8.7e-19 67.4 1.9 2.6e-18 65.9 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 PRP78642.1 - 5.2e-15 54.7 0.8 5.2e-15 54.7 0.8 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 PRP78642.1 - 3.8e-09 36.4 4.5 7.7e-09 35.4 0.6 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 PRP78642.1 - 1.2 9.0 8.3 3.3 7.7 0.4 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain AAA PF00004.29 PRP78643.1 - 5.8e-38 130.3 0.0 1.3e-37 129.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP78643.1 - 5e-11 42.2 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 PRP78643.1 - 3.9e-07 30.0 0.2 2e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 PRP78643.1 - 1.8e-05 24.6 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PRP78643.1 - 4.3e-05 23.7 0.0 8.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 PRP78643.1 - 7.6e-05 22.9 0.0 0.00048 20.3 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PRP78643.1 - 0.0005 20.5 0.3 0.16 12.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PRP78643.1 - 0.00098 19.1 0.2 0.0045 17.0 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PRP78643.1 - 0.0012 18.3 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PRP78643.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 PRP78643.1 - 0.0031 18.1 0.3 0.02 15.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 PRP78643.1 - 0.0039 17.0 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 PRP78643.1 - 0.0041 17.4 0.3 0.043 14.1 0.2 2.5 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 PRP78643.1 - 0.0067 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 PRP78643.1 - 0.0074 16.3 0.0 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PRP78643.1 - 0.015 15.5 0.2 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 PRP78643.1 - 0.023 15.1 0.0 0.083 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PRP78643.1 - 0.043 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 PRP78643.1 - 0.049 13.0 0.3 6.6 6.0 0.1 2.4 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.6 PRP78643.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PRP78643.1 - 0.054 13.0 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 PRP78643.1 - 0.091 13.2 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 PRP78643.1 - 0.099 12.2 0.5 0.32 10.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain C2 PF00168.30 PRP78644.1 - 8.4e-26 90.3 0.0 1.9e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain L51_S25_CI-B8 PF05047.16 PRP78644.1 - 0.12 12.4 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Tom22 PF04281.13 PRP78645.1 - 0.068 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 baeRF_family10 PF18854.1 PRP78645.1 - 0.22 11.8 3.5 15 5.9 0.7 3.2 3 1 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 10 Mso1_C PF14477.6 PRP78646.1 - 0.026 14.9 1.0 0.052 14.0 1.0 1.6 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 HSP70 PF00012.20 PRP78647.1 - 7e-83 278.8 4.1 7e-75 252.4 0.3 3.2 1 1 2 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.13 PRP78647.1 - 1.5e-07 30.6 0.1 2.5e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein SIR2 PF02146.17 PRP78648.1 - 1.2e-22 80.7 0.0 2.2e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Sir2 family Cyclin PF08613.11 PRP78648.1 - 0.0027 18.1 0.0 0.0067 16.8 0.0 1.8 1 0 0 1 1 1 1 Cyclin TPP_enzyme_M PF00205.22 PRP78648.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain RhoGEF PF00621.20 PRP78649.1 - 1.8e-32 113.1 1.4 1.3e-22 81.0 1.2 2.6 1 1 1 2 2 2 2 RhoGEF domain Ank_3 PF13606.6 PRP78649.1 - 7.1e-16 56.7 2.3 9.1e-05 22.6 0.2 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 PRP78649.1 - 2e-15 57.1 0.1 6.2e-07 29.9 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78649.1 - 3.8e-15 56.0 1.6 5.6e-06 26.8 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP78649.1 - 3.9e-13 49.4 0.3 5e-05 23.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 PRP78649.1 - 7.1e-06 26.5 0.0 2.3e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 PH domain Ank PF00023.30 PRP78649.1 - 7.3e-06 26.2 3.3 0.0027 18.1 0.0 3.8 5 0 0 5 5 5 2 Ankyrin repeat RR_TM4-6 PF06459.12 PRP78649.1 - 0.66 9.7 17.2 0.75 9.6 15.0 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CorA PF01544.18 PRP78649.1 - 0.73 9.1 5.6 3.8 6.7 0.8 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Peptidase_S64 PF08192.11 PRP78649.1 - 8.3 4.8 8.4 16 3.8 8.4 1.4 1 0 0 1 1 1 0 Peptidase family S64 RGS PF00615.19 PRP78650.1 - 0.00038 20.7 0.0 0.00068 19.9 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Ank_2 PF12796.7 PRP78651.1 - 1.2e-40 137.9 0.0 9.3e-09 35.8 0.0 5.0 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78651.1 - 2e-25 88.8 0.5 0.0011 19.5 0.0 9.0 3 3 7 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP78651.1 - 4.1e-22 78.0 0.3 0.005 17.1 0.0 9.1 3 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP78651.1 - 2.9e-13 49.6 5.3 0.34 11.5 0.2 10.0 8 4 2 10 10 10 3 Ankyrin repeat Ank_3 PF13606.6 PRP78651.1 - 9.9e-10 37.8 0.1 2.2 9.1 0.0 9.1 10 0 0 10 10 10 1 Ankyrin repeat RGS PF00615.19 PRP78651.1 - 3.4e-06 27.3 0.2 6.6e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3562 PF12085.8 PRP78651.1 - 5.8 6.6 7.3 1.8 8.2 0.4 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3562) zf-ZPR1 PF03367.13 PRP78652.1 - 1.3e-115 382.6 0.1 9.8e-59 197.8 0.1 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 PRP78652.1 - 0.13 12.3 2.6 1.1 9.3 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbons DiS_P_DiS PF06750.13 PRP78652.1 - 1.6 8.9 6.7 9.9 6.4 0.2 3.4 2 2 1 3 3 3 0 Bacterial Peptidase A24 N-terminal domain HgmA PF04209.13 PRP78653.1 - 2.5e-206 685.4 0.3 3e-206 685.1 0.3 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Ras PF00071.22 PRP78653.1 - 2e-46 157.6 0.0 3.3e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP78653.1 - 5.9e-14 52.3 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP78653.1 - 0.00024 20.6 0.0 0.00035 20.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ank_2 PF12796.7 PRP78655.1 - 7.1e-31 106.6 0.0 2.3e-10 40.9 0.0 4.6 1 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78655.1 - 3.4e-29 100.9 0.2 8.9e-06 26.2 0.0 7.2 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP78655.1 - 7.7e-17 60.9 4.2 0.14 12.7 0.0 9.7 9 1 2 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 PRP78655.1 - 2.3e-15 56.5 0.7 0.081 13.3 0.0 9.5 3 2 8 11 11 11 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78655.1 - 3.9e-15 54.4 0.0 11 6.9 0.0 10.8 9 2 2 11 11 11 2 Ankyrin repeat DUF3734 PF12536.8 PRP78655.1 - 0.0021 18.4 0.2 16 5.9 0.0 3.6 2 1 1 3 3 3 2 Patatin phospholipase Hairy_orange PF07527.13 PRP78655.1 - 0.059 13.6 2.8 9 6.6 0.0 4.8 6 0 0 6 6 6 0 Hairy Orange HSP70 PF00012.20 PRP78656.1 - 3e-38 131.4 2.4 2.8e-31 108.4 1.5 2.8 1 1 1 2 2 2 2 Hsp70 protein RCC1 PF00415.18 PRP78657.1 - 9.4e-57 189.5 26.5 2.1e-13 50.6 0.2 8.8 8 1 1 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP78657.1 - 7.2e-52 172.3 32.6 4e-09 36.0 0.3 8.5 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat DUF3623 PF12291.8 PRP78657.1 - 0.00052 19.3 0.3 0.0069 15.6 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3623) Peptidase_C25_C PF03785.14 PRP78657.1 - 0.0012 18.6 0.4 0.042 13.7 0.1 3.4 3 1 1 4 4 4 1 Peptidase family C25, C terminal ig-like domain SUKH-3 PF14433.6 PRP78657.1 - 0.052 14.0 3.5 54 4.2 0.0 4.5 3 1 1 5 5 5 0 SUKH-3 immunity protein Thioredoxin_6 PF13848.6 PRP78657.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Hira PF07569.11 PRP78657.1 - 0.16 11.6 0.2 6.5 6.4 0.0 3.3 4 1 0 4 4 4 0 TUP1-like enhancer of split ETF_alpha PF00766.19 PRP78657.1 - 0.19 11.8 1.1 1.5 8.9 0.7 2.6 1 1 1 2 2 2 0 Electron transfer flavoprotein FAD-binding domain PA-IL PF07828.12 PRP78657.1 - 1.2 9.1 5.5 0.56 10.2 0.3 2.7 2 1 1 3 3 3 0 PA-IL-like protein PAD_porph PF04371.15 PRP78658.1 - 3.5e-84 282.8 0.0 4e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 PRP78658.1 - 0.0051 15.9 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 Amidinotransferase Pecanex_C PF05041.15 PRP78660.1 - 7.2e-58 195.9 0.0 1.6e-57 194.8 0.0 1.5 1 0 0 1 1 1 1 Pecanex protein (C-terminus) zf-CCCH PF00642.24 PRP78661.1 - 3.8e-18 64.9 40.9 3.7e-05 23.5 2.2 5.5 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP78661.1 - 1.4e-16 59.9 50.3 4.3e-07 29.8 3.7 6.6 6 1 0 6 6 6 4 Zinc finger domain Torus PF16131.5 PRP78661.1 - 1.8e-14 54.3 27.1 0.00085 20.0 0.3 5.4 1 1 4 5 5 5 5 Torus domain zf-CCHC PF00098.23 PRP78661.1 - 4.4e-10 39.2 19.6 2.9e-05 23.9 2.7 3.8 3 0 0 3 3 3 2 Zinc knuckle zf-CCCH_4 PF18044.1 PRP78661.1 - 1.1e-08 34.6 32.7 0.00014 21.6 1.4 5.3 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 PRP78661.1 - 1.3e-08 35.0 8.6 1.3e-08 35.0 8.6 2.8 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCHC_3 PF13917.6 PRP78661.1 - 0.0021 18.0 9.8 0.092 12.7 1.5 3.1 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 PRP78661.1 - 0.0025 17.5 8.4 0.17 11.6 0.6 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCCH_2 PF14608.6 PRP78661.1 - 0.0056 17.1 3.4 0.0056 17.1 3.4 6.9 8 1 0 8 8 8 4 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 PRP78661.1 - 0.019 14.7 16.3 1.8 8.4 0.1 5.0 4 0 0 4 4 4 0 Putative zinc-finger domain CLP1_P PF16575.5 PRP78662.1 - 1.4e-58 197.8 0.0 2.2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 PRP78662.1 - 9e-27 93.1 0.1 1.5e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 PRP78662.1 - 1.2e-18 67.6 0.1 3.1e-18 66.3 0.1 1.7 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CbiA PF01656.23 PRP78662.1 - 0.00042 20.4 0.0 0.00091 19.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.23 PRP78662.1 - 0.015 15.3 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 PRP78662.1 - 0.024 15.2 0.0 0.043 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.7 PRP78662.1 - 0.066 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 PRP78662.1 - 0.18 12.1 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain GCP_C_terminal PF04130.13 PRP78664.1 - 2.6e-69 234.0 5.5 2.6e-69 234.0 5.5 2.3 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PRP78664.1 - 3.2e-69 233.9 5.6 3.2e-69 233.9 5.6 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Ca_chan_IQ PF08763.11 PRP78664.1 - 0.087 13.0 0.4 0.67 10.2 0.0 2.7 3 0 0 3 3 3 0 Voltage gated calcium channel IQ domain MIF4G PF02854.19 PRP78665.1 - 5.8e-07 29.4 0.5 9.7e-07 28.6 0.5 1.4 1 1 0 1 1 1 1 MIF4G domain RRN3 PF05327.11 PRP78665.1 - 0.035 12.7 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 tRNA-synt_2b PF00587.25 PRP78666.1 - 2.1e-36 125.5 0.0 3.7e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PRP78666.1 - 4.2e-11 42.8 0.0 8.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain ODR4-like PF14778.6 PRP78667.1 - 6.8e-57 193.1 0.5 8.9e-57 192.7 0.5 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like zf-piccolo PF05715.13 PRP78668.1 - 0.18 11.9 1.9 0.68 10.1 0.0 2.4 3 0 0 3 3 3 0 Piccolo Zn-finger G8 PF10162.9 PRP78670.1 - 7.3e-22 77.7 0.0 1.9e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 G8 domain Zn_clus PF00172.18 PRP78672.1 - 0.00029 20.9 12.6 0.00063 19.8 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.7 PRP78672.1 - 0.038 14.3 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.7 PRP78672.1 - 0.091 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 PAS domain Robl_LC7 PF03259.17 PRP78673.1 - 0.0035 17.1 1.5 0.0051 16.5 0.5 1.8 2 0 0 2 2 2 1 Roadblock/LC7 domain PAS_9 PF13426.7 PRP78673.1 - 0.059 13.6 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 PAS domain 2-oxoacid_dh PF00198.23 PRP78674.1 - 1.6e-81 273.2 0.0 2.3e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PRP78674.1 - 5.5e-18 64.6 0.2 1.2e-17 63.5 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 PRP78674.1 - 3.6e-14 52.8 2.7 4.9e-14 52.4 0.5 2.4 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 PRP78674.1 - 0.0025 17.6 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like CPSF100_C PF13299.6 PRP78674.1 - 0.095 12.9 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Methyltransf_31 PF13847.6 PRP78675.1 - 1.1e-08 35.1 0.1 6.4e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 PRP78675.1 - 3.1e-07 31.0 0.1 0.00076 20.1 0.1 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 PRP78675.1 - 2e-05 25.2 0.0 0.0096 16.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP78675.1 - 7.1e-05 22.7 0.0 9.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 PRP78675.1 - 0.00075 19.2 0.0 0.0017 18.0 0.0 1.6 1 1 1 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_8 PF05148.15 PRP78675.1 - 0.053 13.4 0.0 0.08 12.8 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_12 PF08242.12 PRP78675.1 - 0.082 13.7 0.1 1.2 9.9 0.1 2.2 1 1 1 2 2 2 0 Methyltransferase domain Pkinase_Tyr PF07714.17 PRP78677.1 - 5.9e-141 468.2 0.0 1e-69 234.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP78677.1 - 2.9e-93 312.1 0.0 1.6e-45 155.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 PRP78677.1 - 8.6e-20 70.3 70.4 1.2e-05 25.0 4.3 10.7 10 1 1 11 11 11 7 Leucine rich repeat Pkinase_fungal PF17667.1 PRP78677.1 - 3.8e-07 29.2 0.4 0.014 14.2 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase LRRNT_2 PF08263.12 PRP78677.1 - 1.6e-05 25.1 12.1 0.002 18.4 2.7 2.9 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain Kdo PF06293.14 PRP78677.1 - 2.8e-05 23.6 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family EphA2_TM PF14575.6 PRP78677.1 - 0.0023 18.8 1.1 2.6 9.0 0.1 2.7 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 PRP78677.1 - 0.0044 16.8 2.3 2 8.3 0.2 2.7 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain Kinase-like PF14531.6 PRP78677.1 - 0.0099 15.2 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Phage_holin_3_6 PF07332.11 PRP78677.1 - 0.01 15.8 0.2 9.2 6.3 0.0 2.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Epiglycanin_C PF14654.6 PRP78677.1 - 0.014 15.4 2.9 1.4 9.0 0.2 3.3 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region TMEM154 PF15102.6 PRP78677.1 - 0.032 14.1 8.5 1.2 9.1 0.0 3.4 4 0 0 4 4 3 0 TMEM154 protein family DUF4381 PF14316.6 PRP78677.1 - 0.038 14.2 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4083 PF13314.6 PRP78677.1 - 0.056 13.4 2.8 1.9 8.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) MAP17 PF15807.5 PRP78677.1 - 0.059 13.6 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 OSTbeta PF15048.6 PRP78677.1 - 0.083 13.0 0.2 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Haspin_kinase PF12330.8 PRP78677.1 - 0.1 11.5 0.5 12 4.7 0.1 2.5 2 0 0 2 2 2 0 Haspin like kinase domain LRR_4 PF12799.7 PRP78677.1 - 0.14 12.6 112.0 0.09 13.2 9.6 15.5 11 3 3 17 17 14 0 Leucine Rich repeats (2 copies) Sigma_reg_N PF13800.6 PRP78677.1 - 0.16 12.3 3.2 7 7.0 0.1 3.3 3 0 0 3 3 2 0 Sigma factor regulator N-terminal DUF1180 PF06679.12 PRP78677.1 - 0.18 12.2 1.6 43 4.5 0.0 4.4 4 0 0 4 4 3 0 Protein of unknown function (DUF1180) Baculo_11_kDa PF06143.11 PRP78677.1 - 0.27 10.8 6.6 2.1 8.0 1.1 2.7 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF2771 PF10969.8 PRP78677.1 - 0.99 9.4 3.5 49 3.9 0.2 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF2771) DUF4107 PF13389.6 PRP78677.1 - 1.5 8.9 10.6 5.9 7.0 0.2 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF4107) TMEM208_SND2 PF05620.11 PRP78678.1 - 2.9e-40 137.8 4.1 3.1e-40 137.7 4.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 TMEM37 PF15108.6 PRP78678.1 - 0.13 12.1 7.3 0.21 11.5 7.3 1.2 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family DUF2070 PF09843.9 PRP78678.1 - 0.84 7.9 4.8 1 7.5 4.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Beach PF02138.18 PRP78680.1 - 3e-116 387.6 0.0 7e-116 386.4 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 PRP78680.1 - 6.3e-58 196.2 0.6 6.3e-58 196.2 0.6 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 PRP78680.1 - 4e-15 56.3 0.0 1.2e-12 48.2 0.0 2.5 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 PRP78680.1 - 5.6e-15 55.3 3.9 6.4e-13 48.7 3.9 2.7 1 1 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 PRP78680.1 - 2.3e-10 40.2 7.9 2.3e-10 40.2 7.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4800) WD40 PF00400.32 PRP78680.1 - 6.1e-09 36.4 5.7 0.00049 20.9 0.3 3.6 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1088 PF06469.11 PRP78680.1 - 6.9e-05 22.6 1.1 0.00015 21.5 1.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) Rcd1 PF04078.13 PRP78680.1 - 0.03 13.6 0.9 1.3 8.2 0.1 2.9 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like MFS_1 PF07690.16 PRP78681.1 - 2.1e-10 40.1 26.1 5.5e-08 32.1 2.7 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily DAGK_acc PF00609.19 PRP78681.1 - 1.4e-06 28.8 0.1 2.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain UPF0565 PF10561.9 PRP78682.1 - 0.021 14.1 3.5 0.02 14.1 3.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 TLP-20 PF06088.11 PRP78682.1 - 0.021 14.7 4.2 0.022 14.7 4.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Podoplanin PF05808.11 PRP78682.1 - 0.023 14.8 2.7 0.025 14.7 2.7 1.2 1 0 0 1 1 1 0 Podoplanin DUF4746 PF15928.5 PRP78682.1 - 0.19 11.1 6.7 0.21 11.0 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CCDC106 PF15794.5 PRP78682.1 - 0.3 10.8 12.1 0.34 10.6 12.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF913 PF06025.12 PRP78682.1 - 0.82 8.6 6.1 0.87 8.5 6.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4834 PF16118.5 PRP78682.1 - 3.5 8.7 6.3 4.9 8.2 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 PRP78682.1 - 6.6 6.7 6.1 6.7 6.7 6.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 PRP78682.1 - 8.1 5.6 7.1 8.5 5.5 7.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 PRP78682.1 - 9.8 4.8 10.1 10 4.8 10.1 1.0 1 0 0 1 1 1 0 Presenilin PBP1_TM PF14812.6 PRP78682.1 - 9.9 6.6 10.8 13 6.2 10.8 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UQ_con PF00179.26 PRP78684.1 - 9.4e-19 67.5 0.3 1.7e-18 66.6 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DcpS_C PF11969.8 PRP78684.1 - 8.8e-14 52.0 0.4 9.6e-13 48.6 0.2 2.2 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 PRP78684.1 - 4.4e-10 40.2 1.2 1.2e-09 38.8 1.2 1.7 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 PRP78684.1 - 0.046 13.6 0.2 0.095 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 EGF_2 PF07974.13 PRP78685.1 - 0.00022 21.5 9.3 0.00022 21.5 9.3 2.4 1 1 1 2 2 2 1 EGF-like domain EGF PF00008.27 PRP78685.1 - 0.019 15.2 2.6 0.019 15.2 2.6 1.9 1 1 1 2 2 2 0 EGF-like domain hEGF PF12661.7 PRP78685.1 - 0.61 10.8 9.9 0.13 12.9 3.1 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF C2 PF00168.30 PRP78686.1 - 9.6e-25 86.9 0.0 1.2e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain TruB_N PF01509.18 PRP78687.1 - 0.34 11.3 1.6 5.2 7.4 0.0 2.9 2 1 1 3 3 3 0 TruB family pseudouridylate synthase (N terminal domain) PMI_typeI PF01238.21 PRP78688.1 - 1.9e-105 353.2 0.0 2.3e-105 352.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 PRP78688.1 - 1.6e-06 28.1 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.11 PRP78688.1 - 3.9e-05 23.3 0.0 0.049 13.4 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.7 PRP78688.1 - 0.011 15.5 0.0 0.068 12.9 0.0 2.0 2 0 0 2 2 2 0 Cupin GnsAB_toxin PF08178.11 PRP78688.1 - 0.36 10.8 2.3 2.8 7.9 0.1 2.7 3 0 0 3 3 3 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Pkinase_Tyr PF07714.17 PRP78689.1 - 9.5e-71 238.1 0.0 1.5e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78689.1 - 1.4e-51 175.4 0.0 2.1e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP78689.1 - 1.8e-32 110.9 73.1 9.4e-08 31.7 2.8 13.6 7 2 6 14 14 14 10 Leucine rich repeat LRR_4 PF12799.7 PRP78689.1 - 7.6e-24 83.4 74.8 0.00042 20.6 0.2 13.8 11 4 3 14 14 14 9 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP78689.1 - 0.00018 20.9 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP78689.1 - 0.00039 19.3 0.0 0.00062 18.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP78689.1 - 0.00051 19.5 0.3 0.001 18.5 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_1 PF00560.33 PRP78689.1 - 0.00088 19.5 61.0 0.44 11.3 0.5 16.2 16 4 1 17 17 15 3 Leucine Rich Repeat Podoplanin PF05808.11 PRP78689.1 - 0.043 13.9 0.1 0.083 13.0 0.1 1.3 1 0 0 1 1 1 0 Podoplanin LRRNT_2 PF08263.12 PRP78689.1 - 0.095 13.0 0.9 0.21 11.9 0.9 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain APH PF01636.23 PRP78689.1 - 0.11 12.4 1.1 1.7 8.5 0.4 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_5 PF13306.6 PRP78689.1 - 0.12 12.3 3.0 1.3 9.0 0.1 3.5 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Phosphorylase PF00343.20 PRP78690.1 - 3.2e-284 944.7 0.0 3.7e-284 944.5 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CRAL_TRIO PF00650.20 PRP78691.1 - 1.1e-21 77.2 0.1 2.2e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PRP78691.1 - 0.0012 19.0 0.2 0.0021 18.2 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Ferritin-like PF12902.7 PRP78691.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like Bin3 PF06859.12 PRP78693.1 - 2.2e-22 79.7 0.0 3.7e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 PRP78693.1 - 2.3e-07 30.7 0.1 2.9e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP78693.1 - 9.3e-05 23.1 0.1 0.00027 21.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP78693.1 - 0.00031 21.3 0.0 0.00056 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP78693.1 - 0.00044 20.1 0.0 0.00062 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP78693.1 - 0.0011 19.7 0.1 0.0026 18.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 PRP78693.1 - 0.039 13.6 0.0 0.19 11.3 0.0 1.9 1 1 0 1 1 1 0 Nodulation protein S (NodS) SPRY PF00622.28 PRP78694.1 - 2.6e-11 43.7 0.1 6.4e-11 42.4 0.1 1.6 2 0 0 2 2 2 1 SPRY domain F-box-like PF12937.7 PRP78694.1 - 2.9e-09 36.7 3.1 3.2e-08 33.3 0.6 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP78694.1 - 2.9e-09 36.6 0.6 2.9e-09 36.6 0.6 2.1 2 0 0 2 2 2 1 F-box domain CRAL_TRIO PF00650.20 PRP78695.1 - 6.3e-34 117.0 0.0 8.5e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PRP78695.1 - 0.00014 22.0 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP78695.1 - 0.0012 19.0 2.1 0.0028 17.8 2.1 1.7 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain BRCT PF00533.26 PRP78696.1 - 4.2e-09 36.7 0.0 3.4e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP78696.1 - 3.6e-07 30.5 0.0 0.047 14.1 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PRP78696.1 - 1.9e-06 27.7 0.0 0.00027 20.8 0.0 2.8 2 1 1 3 3 3 1 twin BRCT domain BRCT_3 PF18428.1 PRP78696.1 - 0.029 14.5 0.0 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Sulfate_transp PF00916.20 PRP78698.1 - 2.5e-94 316.2 23.6 3.7e-94 315.6 23.6 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PRP78698.1 - 1.9e-12 46.8 0.0 3.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF3429 PF11911.8 PRP78699.1 - 3.6e-32 111.6 7.7 4.4e-32 111.3 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF5360 PF17314.2 PRP78699.1 - 0.062 13.4 0.6 0.094 12.8 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5360) HsbA PF12296.8 PRP78700.1 - 1e-14 55.0 2.7 1.7e-14 54.3 2.7 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A WRNPLPNID PF15017.6 PRP78700.1 - 0.027 15.3 0.2 0.053 14.4 0.2 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Methyltransf_11 PF08241.12 PRP78701.1 - 4.4e-22 78.5 0.0 8e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP78701.1 - 3.5e-20 72.5 0.0 5.9e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP78701.1 - 3.6e-14 52.8 0.0 5.3e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP78701.1 - 5e-12 46.4 0.0 1.2e-11 45.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP78701.1 - 2.8e-11 43.5 0.0 4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP78701.1 - 2.9e-10 39.9 0.0 4.5e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PRP78701.1 - 0.00021 20.9 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 PRP78701.1 - 0.00037 20.4 0.0 0.0016 18.4 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 PRP78701.1 - 0.00068 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 PRP78701.1 - 0.0024 17.2 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 PRP78701.1 - 0.011 15.6 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 PRP78701.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 PRP78701.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 PRP78701.1 - 0.029 13.7 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_PK PF05891.12 PRP78701.1 - 0.049 13.1 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_15 PF09445.10 PRP78701.1 - 0.097 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.16 PRP78701.1 - 0.1 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 PRP78701.1 - 0.1 12.1 0.0 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Cons_hypoth95 PF03602.15 PRP78701.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MFS_1 PF07690.16 PRP78702.1 - 6.7e-36 123.9 27.1 5.5e-34 117.7 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PRP78702.1 - 5.4e-11 41.6 0.4 8.9e-11 40.9 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 PRP78702.1 - 2.5e-08 33.2 7.7 2.5e-08 33.2 7.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Cyt-b5 PF00173.28 PRP78703.1 - 3.2e-24 84.9 0.1 3.6e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3931 PF13082.6 PRP78703.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) DUF3818 PF12825.7 PRP78704.1 - 2.8e-23 82.5 0.1 7e-23 81.2 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) MIP PF00230.20 PRP78705.1 - 3.5e-61 206.8 13.0 4.9e-61 206.3 13.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF2721 PF11026.8 PRP78705.1 - 0.17 11.8 1.7 0.53 10.2 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) RhoGEF PF00621.20 PRP78706.1 - 5.7e-43 147.3 0.2 5.7e-43 147.3 0.2 2.4 2 1 0 3 3 3 1 RhoGEF domain Nup54 PF13874.6 PRP78706.1 - 0.00025 21.2 6.4 0.00066 19.8 6.4 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 PH_16 PF17838.1 PRP78706.1 - 0.0051 16.7 0.1 0.012 15.5 0.1 1.6 1 0 0 1 1 1 1 PH domain DUF2013 PF09431.10 PRP78706.1 - 0.014 15.5 0.7 0.062 13.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2013) bZIP_1 PF00170.21 PRP78706.1 - 0.022 14.8 5.9 0.53 10.4 0.1 3.6 2 1 1 3 3 3 0 bZIP transcription factor RNA_pol_Rpb1_R PF05001.13 PRP78706.1 - 0.37 11.2 6.7 1 9.8 3.5 2.6 1 1 1 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat ADIP PF11559.8 PRP78706.1 - 0.4 10.8 11.5 0.022 14.9 5.7 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 PRP78706.1 - 0.77 9.5 6.3 5 6.9 0.5 2.6 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Snapin_Pallidin PF14712.6 PRP78706.1 - 2.6 8.5 7.0 0.43 11.0 1.1 2.7 3 0 0 3 3 3 0 Snapin/Pallidin bZIP_2 PF07716.15 PRP78706.1 - 2.8 8.1 12.4 1.3 9.2 2.1 3.3 3 0 0 3 3 3 0 Basic region leucine zipper ZapB PF06005.12 PRP78706.1 - 8 7.0 16.1 3 8.4 6.5 3.1 2 1 1 3 3 3 0 Cell division protein ZapB UvrD_C PF13361.6 PRP78707.1 - 5.4e-13 49.1 0.0 8.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 PRP78707.1 - 1.6e-05 24.6 0.3 0.00017 21.3 0.3 2.2 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Pkinase_Tyr PF07714.17 PRP78710.1 - 2.3e-73 246.7 0.0 3.5e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78710.1 - 1.4e-46 159.0 0.0 2.5e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RhoGAP PF00620.27 PRP78710.1 - 4e-33 114.4 0.0 7.4e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Sec7 PF01369.20 PRP78710.1 - 6.2e-17 61.9 0.1 1.2e-16 60.9 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 PRP78710.1 - 1e-11 45.2 0.9 2.9e-11 43.8 0.9 1.9 1 0 0 1 1 1 1 PH domain F-box-like PF12937.7 PRP78710.1 - 9.7e-08 31.8 0.2 3.2e-07 30.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP78710.1 - 3.4e-07 30.0 1.7 3.4e-07 30.0 1.7 1.9 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 PRP78710.1 - 5.5e-06 26.0 1.9 0.11 12.3 0.2 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PRP78710.1 - 6.2e-06 26.5 2.5 1.8 9.1 0.1 5.2 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) PH_11 PF15413.6 PRP78710.1 - 0.014 15.8 0.4 0.058 13.8 0.4 2.2 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_1 PF00560.33 PRP78710.1 - 0.019 15.5 4.6 9.5 7.2 0.1 5.7 5 1 0 5 5 3 0 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP78710.1 - 0.029 13.2 1.4 0.031 13.1 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase LRRNT_2 PF08263.12 PRP78710.1 - 0.036 14.4 2.0 0.092 13.1 2.0 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain PH_3 PF14593.6 PRP78710.1 - 0.049 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 PH domain MHYT PF03707.16 PRP78710.1 - 0.12 12.5 1.1 0.36 11.0 1.1 1.7 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Glycoprotein_G PF00802.19 PRP78710.1 - 0.28 10.5 2.0 0.35 10.2 0.2 2.1 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G Sec62 PF03839.16 PRP78711.1 - 1.3e-38 132.7 8.1 1.3e-38 132.7 8.1 2.3 1 1 1 2 2 2 2 Translocation protein Sec62 DUF3915 PF13054.6 PRP78711.1 - 0.088 12.8 0.9 0.13 12.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Med19 PF10278.9 PRP78711.1 - 0.61 10.0 13.4 0.93 9.4 13.4 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TMEM214 PF10151.9 PRP78711.1 - 1.8 6.9 7.7 2.5 6.5 7.7 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator NARP1 PF12569.8 PRP78711.1 - 7.7 5.3 12.2 10 4.9 12.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DASH_Duo1 PF08651.10 PRP78712.1 - 0.0023 17.7 1.0 0.0037 17.0 1.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF2674 PF10879.8 PRP78712.1 - 0.012 15.2 0.1 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) Peptidase_S46 PF10459.9 PRP78712.1 - 0.017 13.8 2.4 0.018 13.7 2.4 1.0 1 0 0 1 1 1 0 Peptidase S46 SesA PF17107.5 PRP78712.1 - 0.025 14.8 1.8 0.038 14.2 1.8 1.4 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PI_PP_I PF18363.1 PRP78712.1 - 0.041 14.1 0.3 0.052 13.7 0.3 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Allexi_40kDa PF05549.11 PRP78712.1 - 0.094 12.2 1.7 0.11 12.1 1.7 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Syntaxin-6_N PF09177.11 PRP78712.1 - 0.54 10.9 4.9 1.4 9.5 4.9 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMPIT PF07851.13 PRP78712.1 - 0.76 9.0 3.6 0.86 8.8 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Muted PF14942.6 PRP78712.1 - 0.81 10.0 6.3 1.8 8.9 0.4 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Peptidase_M8 PF01457.16 PRP78713.1 - 1.1e-59 202.6 4.1 1.8e-59 201.9 4.1 1.2 1 0 0 1 1 1 1 Leishmanolysin DEAD PF00270.29 PRP78714.1 - 9e-45 152.6 0.1 2.4e-44 151.2 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP78714.1 - 3e-24 85.5 0.5 3e-22 79.0 0.0 2.8 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78714.1 - 1.3e-08 35.0 2.9 2.3e-08 34.2 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Taxilin PF09728.9 PRP78716.1 - 0.00078 18.7 26.6 0.0017 17.6 26.6 1.6 1 1 0 1 1 1 1 Myosin-like coiled-coil protein MAP PF03642.13 PRP78716.1 - 0.025 14.9 1.9 0.028 14.7 0.6 1.7 2 0 0 2 2 2 0 MAP domain Vip3A_N PF12495.8 PRP78716.1 - 0.36 10.7 4.9 0.31 10.9 3.3 1.7 1 1 1 2 2 2 0 Vegetative insecticide protein 3A N terminal RasGAP_C PF03836.15 PRP78716.1 - 0.36 11.0 21.7 1.2 9.3 8.7 2.3 1 1 1 2 2 2 0 RasGAP C-terminus Gly_acyl_tr_N PF06021.11 PRP78716.1 - 3.5 7.7 15.2 0.58 10.2 3.6 2.3 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase ABC1 PF03109.16 PRP78717.1 - 2.6e-29 101.8 0.7 4.2e-29 101.1 0.2 1.6 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 PRP78717.1 - 0.0016 17.9 0.0 0.0041 16.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain PH_17 PF18012.1 PRP78717.1 - 0.051 13.3 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 PH domain IZUMO PF15005.6 PRP78717.1 - 0.31 11.5 0.9 0.71 10.4 0.9 1.5 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Prp18 PF02840.15 PRP78718.1 - 1.8e-59 199.9 1.8 1.8e-59 199.9 1.8 2.4 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 PRP78718.1 - 1.3e-06 27.8 0.0 2.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Pectate_lyase_3 PF12708.7 PRP78719.1 - 7.4e-06 26.0 11.1 0.00038 20.4 11.1 2.8 1 1 0 1 1 1 1 Pectate lyase superfamily protein ABC2_membrane PF01061.24 PRP78720.1 - 2.4e-34 118.6 23.9 2.4e-34 118.6 23.9 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PRP78720.1 - 5.7e-26 91.7 0.0 2.5e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PRP78720.1 - 0.00019 21.4 0.1 1.2 8.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PRP78720.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 PRP78720.1 - 0.019 14.9 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_23 PF13476.6 PRP78720.1 - 0.022 15.3 0.4 0.16 12.5 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PRP78720.1 - 0.04 14.2 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PRP78720.1 - 0.043 13.4 0.1 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 PRP78720.1 - 0.082 12.8 0.2 0.082 12.8 0.2 2.2 2 0 0 2 2 2 0 CDR ABC transporter PDR_assoc PF08370.11 PRP78720.1 - 0.086 12.6 0.3 0.51 10.1 0.3 2.3 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_29 PF13555.6 PRP78720.1 - 0.11 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pannexin_like PF12534.8 PRP78720.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AAA_16 PF13191.6 PRP78720.1 - 0.18 12.2 0.2 0.38 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 PRP78720.1 - 0.51 10.6 2.0 0.38 11.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 PRP78721.1 - 2.3e-15 56.1 0.0 3.5e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PRP78721.1 - 1.1e-08 34.8 4.3 1.7e-08 34.1 4.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 PRP78721.1 - 0.0001 21.9 3.1 0.00024 20.7 3.1 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 PRP78721.1 - 0.0019 18.0 2.7 0.003 17.4 2.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 PRP78721.1 - 0.0029 17.5 0.8 0.0042 17.0 0.0 1.6 2 0 0 2 2 2 1 Zinc knuckle RRM_5 PF13893.6 PRP78721.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RFC1 PF08519.12 PRP78722.1 - 5.3e-47 159.9 0.0 1.9e-46 158.1 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 PRP78722.1 - 1.2e-10 41.9 0.0 2.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 PRP78722.1 - 1.7e-10 41.1 0.0 4.3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 PRP78722.1 - 5.9e-07 29.6 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 PRP78722.1 - 0.0016 18.9 0.0 0.0042 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 PRP78722.1 - 0.0029 17.7 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain PTCB-BRCT PF12738.7 PRP78722.1 - 0.004 17.1 0.0 0.0097 15.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain AAA_22 PF13401.6 PRP78722.1 - 0.0073 16.6 0.0 0.4 10.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PRP78722.1 - 0.031 14.3 0.0 0.085 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PRP78722.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 PRP78722.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 PRP78722.1 - 0.11 12.9 0.1 0.64 10.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 PRP78722.1 - 0.5 10.1 0.0 0.5 10.1 0.0 4.4 3 1 0 4 4 2 0 AAA domain Topoisom_I_N PF02919.15 PRP78724.1 - 1.5e-86 289.3 3.7 1.5e-86 289.3 3.7 3.8 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 PRP78724.1 - 6.6e-72 241.5 12.5 6.6e-72 241.5 12.5 2.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 PRP78724.1 - 5.8e-32 109.4 1.8 5.8e-32 109.4 1.8 2.6 2 0 0 2 2 2 1 C-terminal topoisomerase domain FlxA PF14282.6 PRP78724.1 - 0.00013 21.9 6.0 0.00013 21.9 6.0 6.5 6 1 1 7 7 7 1 FlxA-like protein FWWh PF14922.6 PRP78724.1 - 0.13 12.2 0.9 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function MADF_DNA_bdg PF10545.9 PRP78724.1 - 5.2 7.4 7.8 0.26 11.6 0.3 2.8 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3375 PF11855.8 PRP78724.1 - 7.1 5.4 7.6 0.27 10.1 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Synaptobrevin PF00957.21 PRP78726.1 - 6.3e-24 83.6 1.2 7.9e-24 83.3 1.2 1.2 1 0 0 1 1 1 1 Synaptobrevin F-box-like PF12937.7 PRP78727.1 - 1.3e-11 44.2 0.1 2.8e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP78727.1 - 1.1e-10 41.1 0.3 2.1e-10 40.2 0.3 1.5 1 0 0 1 1 1 1 F-box domain SPRY PF00622.28 PRP78727.1 - 2.3e-10 40.7 0.0 1.1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 SPRY domain F-box_4 PF15966.5 PRP78727.1 - 0.00052 19.9 0.1 0.00087 19.2 0.1 1.4 1 0 0 1 1 1 1 F-box Herpes_Helicase PF02689.14 PRP78727.1 - 0.23 9.4 0.0 0.29 9.0 0.0 1.0 1 0 0 1 1 1 0 Helicase TTKRSYEDQ PF10212.9 PRP78728.1 - 2.4e-19 69.7 13.5 2.9e-19 69.5 13.5 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein PRAI PF00697.22 PRP78728.1 - 0.006 16.4 0.9 0.0082 15.9 0.5 1.5 1 1 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Metal_resist PF13801.6 PRP78728.1 - 0.13 12.5 0.2 0.13 12.5 0.2 1.8 2 0 0 2 2 2 0 Heavy-metal resistance DUF148 PF02520.17 PRP78728.1 - 0.27 11.4 8.2 0.21 11.7 5.1 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF148 IFT57 PF10498.9 PRP78728.1 - 0.29 10.1 14.1 0.61 9.0 14.1 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 UPF0242 PF06785.11 PRP78728.1 - 0.98 9.5 13.8 1.8 8.6 13.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CotJB PF12652.7 PRP78728.1 - 4 7.7 7.7 21 5.4 0.2 3.3 2 1 1 3 3 3 0 CotJB protein Fib_alpha PF08702.10 PRP78728.1 - 4.2 7.6 10.4 1 9.5 6.5 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LegC3_N PF18654.1 PRP78729.1 - 0.0067 15.7 0.4 0.0077 15.5 0.4 1.0 1 0 0 1 1 1 1 LegC3 N-terminal coiled-coil domain AMPK1_CBM PF16561.5 PRP78730.1 - 1.1e-09 38.3 0.1 2e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Ank_2 PF12796.7 PRP78731.1 - 1.7e-60 201.5 0.0 3.6e-11 43.5 0.0 5.5 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78731.1 - 1.3e-38 130.8 0.0 3.7e-06 27.4 0.0 8.6 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 PRP78731.1 - 2.9e-27 93.9 4.3 0.11 13.0 0.0 11.6 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 PRP78731.1 - 4.3e-22 77.9 0.0 0.059 13.7 0.0 9.9 4 2 6 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78731.1 - 7.8e-16 56.6 0.0 11 6.9 0.0 10.2 10 1 1 11 11 11 3 Ankyrin repeat VWA_3_C PF18571.1 PRP78731.1 - 0.0004 20.2 6.5 42 4.1 0.0 8.1 10 0 0 10 10 10 0 von Willebrand factor type A C-terminal domain RRM_1 PF00076.22 PRP78732.1 - 9e-11 41.4 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PRP78732.1 - 0.0029 17.6 0.1 0.0045 17.0 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif Pyr_redox PF00070.27 PRP78732.1 - 0.049 14.2 0.0 0.09 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PI3_PI4_kinase PF00454.27 PRP78734.1 - 1.7e-56 191.8 0.3 7.6e-56 189.7 0.0 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 PRP78734.1 - 1.2e-16 60.9 12.4 3.3e-16 59.5 12.4 1.8 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 PRP78734.1 - 1.8e-06 27.7 0.0 4.3e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 PRP78734.1 - 0.002 18.0 8.1 0.0034 17.3 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) HlyIII PF03006.20 PRP78735.1 - 1.2e-59 201.8 25.7 1.5e-59 201.5 25.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3418 PF11898.8 PRP78735.1 - 0.27 9.8 0.0 0.37 9.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Arrestin_C PF02752.22 PRP78737.1 - 3.1e-07 30.9 1.1 2.3e-06 28.1 0.3 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Phage_glycop_gL PF11108.8 PRP78737.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral glycoprotein L THDPS_N PF14790.6 PRP78737.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal GCN5L1 PF06320.13 PRP78739.1 - 4.7e-40 136.3 4.6 5.3e-40 136.1 4.6 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Arfaptin PF06456.13 PRP78739.1 - 0.0008 19.0 0.4 0.001 18.7 0.4 1.1 1 0 0 1 1 1 1 Arfaptin-like domain Thiol_cytolys_C PF17440.2 PRP78739.1 - 0.027 14.6 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 Thiol-activated cytolysin beta sandwich domain DHR10 PF18595.1 PRP78739.1 - 0.046 13.8 5.0 0.18 11.9 0.2 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Ribosomal_L6e PF01159.19 PRP78740.1 - 4.8e-30 104.4 1.6 8.6e-30 103.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e FAA_hydrolase PF01557.18 PRP78741.1 - 1.6e-54 184.8 0.0 2.7e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 PRP78741.1 - 3.6e-31 107.5 0.0 1.9e-30 105.2 0.0 2.2 3 0 0 3 3 3 1 Fumarylacetoacetase N-terminal Ninjurin PF04923.12 PRP78741.1 - 0.14 12.1 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 Ninjurin PA14 PF07691.12 PRP78742.1 - 1.5e-10 41.1 0.1 4.3e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.18 PRP78742.1 - 5e-07 29.5 7.4 5e-07 29.5 7.4 8.6 8 1 0 8 8 8 3 Dictyostelium (slime mold) repeat Pkinase_Tyr PF07714.17 PRP78743.1 - 8.9e-37 126.8 0.1 2e-36 125.6 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.24 PRP78743.1 - 3.2e-32 110.5 1.0 2.7e-15 56.2 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Pkinase PF00069.25 PRP78743.1 - 3.6e-27 95.4 0.1 6.7e-27 94.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2_2 PF14633.6 PRP78743.1 - 3.7e-09 36.3 0.0 0.00024 20.6 0.0 2.5 2 0 0 2 2 2 2 SH2 domain LRR_8 PF13855.6 PRP78743.1 - 2.4e-08 33.6 6.3 2.5e-07 30.3 5.9 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PRP78743.1 - 1.3e-07 31.8 11.7 4.7e-05 23.7 2.2 4.1 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) IBP39 PF11422.8 PRP78743.1 - 0.0003 20.6 0.1 0.024 14.4 0.0 2.6 2 0 0 2 2 2 1 Initiator binding protein 39 kDa Cbl_N2 PF02761.14 PRP78743.1 - 0.00069 20.3 0.7 0.061 14.0 0.3 2.8 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 PF02762.14 PRP78743.1 - 0.019 14.8 0.3 0.52 10.2 0.2 2.5 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Filamin PF00630.19 PRP78743.1 - 0.082 13.7 0.0 1.8 9.4 0.0 2.5 2 0 0 2 2 2 0 Filamin/ABP280 repeat LRR_1 PF00560.33 PRP78743.1 - 0.19 12.4 4.0 11 7.0 1.0 4.3 3 1 0 3 3 2 0 Leucine Rich Repeat LRR_6 PF13516.6 PRP78743.1 - 4.8 7.5 7.8 1.4 9.1 1.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat HNH_2 PF13391.6 PRP78746.1 - 1.8e-06 28.0 0.2 0.049 13.8 0.0 3.0 2 0 0 2 2 2 2 HNH endonuclease Styelin PF17562.2 PRP78746.1 - 0.0042 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Styelin DUF1400 PF07176.11 PRP78746.1 - 0.029 14.6 1.2 0.092 13.0 0.0 2.5 3 1 1 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) Peptidase_S48 PF03574.15 PRP78746.1 - 0.078 13.2 0.0 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Peptidase family S48 Baculo_8kDa PF06096.11 PRP78746.1 - 0.11 12.7 2.0 10 6.3 0.2 2.6 2 0 0 2 2 2 0 Baculoviridae 8.2 KDa protein Cucumo_2B PF03263.13 PRP78746.1 - 0.15 12.5 2.5 13 6.3 0.1 2.4 2 0 0 2 2 2 0 Cucumovirus protein 2B Pkinase PF00069.25 PRP78751.1 - 3.2e-49 167.7 0.1 4.6e-49 167.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78751.1 - 2e-26 92.8 0.1 3.8e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP78751.1 - 5.1e-05 23.3 0.0 0.00013 22.0 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP78751.1 - 0.00019 20.9 0.0 0.00041 19.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_8 PF13188.7 PRP78751.1 - 0.0043 17.0 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 PAS domain Y1_Tnp PF01797.16 PRP78751.1 - 1.3 9.1 3.9 31 4.7 0.1 4.0 5 0 0 5 5 5 0 Transposase IS200 like HA2 PF04408.23 PRP78752.1 - 1.3e-22 80.1 0.0 2.9e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PRP78752.1 - 1.3e-16 60.7 0.0 2.5e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PRP78752.1 - 1.7e-11 44.4 0.0 4.1e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PRP78752.1 - 1.5e-06 28.5 0.0 4.5e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP78752.1 - 7.8e-05 23.0 0.0 0.00017 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 PRP78752.1 - 7.8e-05 22.5 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP78752.1 - 0.0017 18.4 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SRP54 PF00448.22 PRP78752.1 - 0.0053 16.4 0.2 0.012 15.2 0.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 PRP78752.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PRP78752.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 PRP78752.1 - 0.059 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein HTH_IclR PF09339.10 PRP78752.1 - 0.062 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain ABC_tran PF00005.27 PRP78752.1 - 0.077 13.5 0.1 0.97 9.9 0.1 2.3 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 PRP78752.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PRP78752.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-CHY PF05495.12 PRP78753.1 - 3.2e-14 53.2 13.6 7.1e-14 52.1 13.6 1.5 1 0 0 1 1 1 1 CHY zinc finger zf_UBZ PF18439.1 PRP78753.1 - 0.0037 16.8 7.5 0.46 10.1 0.2 3.4 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf-FPG_IleRS PF06827.14 PRP78753.1 - 0.01 15.7 0.7 0.01 15.7 0.7 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 PRP78753.1 - 0.015 15.4 3.5 0.015 15.4 3.5 2.6 2 1 0 2 2 2 0 Zinc ribbon domain zf_Rg PF17915.1 PRP78753.1 - 0.02 14.3 1.2 1.9 8.0 0.1 2.5 2 0 0 2 2 2 0 Reverse gyrase zinc finger Cys_rich_KTR PF14205.6 PRP78753.1 - 0.021 14.6 6.6 2 8.2 0.1 2.6 1 1 1 2 2 2 0 Cysteine-rich KTR C1_4 PF07975.12 PRP78753.1 - 0.047 13.9 12.4 3.9 7.8 7.2 3.2 1 1 2 3 3 3 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.7 PRP78753.1 - 0.052 13.5 9.4 0.31 11.0 5.9 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain YacG PF03884.14 PRP78753.1 - 0.056 13.2 0.7 0.056 13.2 0.7 2.7 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG DUF4379 PF14311.6 PRP78753.1 - 0.084 13.3 0.3 0.084 13.3 0.3 2.2 2 0 0 2 2 2 0 Probable Zinc-ribbon domain zf-ribbon_3 PF13248.6 PRP78753.1 - 0.19 11.2 9.0 1.4 8.4 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 PRP78753.1 - 0.36 10.8 12.5 1.1 9.2 0.7 3.3 2 1 1 3 3 3 0 zinc-ribbon domain HypA PF01155.19 PRP78753.1 - 0.83 9.7 10.4 0.065 13.3 1.8 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNA_POL_M_15KD PF02150.16 PRP78753.1 - 0.98 9.4 12.0 2.2 8.2 0.1 3.3 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DpnI PF06044.12 PRP78753.1 - 1.7 8.3 6.3 8.9 5.9 1.7 2.1 1 1 1 2 2 2 0 Dam-replacing family DUF3797 PF12677.7 PRP78753.1 - 2.1 8.3 7.8 2 8.4 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) zinc_ribbon_9 PF14369.6 PRP78753.1 - 5.3 7.4 13.0 1.6 9.1 4.2 2.9 1 1 2 3 3 2 0 zinc-ribbon zf-LITAF-like PF10601.9 PRP78753.1 - 8 6.8 11.5 2.5e+02 2.0 10.6 3.1 1 1 0 1 1 1 0 LITAF-like zinc ribbon domain Evr1_Alr PF04777.13 PRP78753.1 - 9.4 6.8 8.8 2.9e+02 2.0 8.8 2.9 1 1 0 1 1 1 0 Erv1 / Alr family TOM20_plant PF06552.12 PRP78754.1 - 1.8e-18 67.0 5.7 3.2e-08 33.6 0.3 6.1 2 1 3 6 6 6 3 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 PRP78754.1 - 6.9e-09 35.3 8.5 0.0002 21.0 0.0 7.4 8 1 0 8 8 8 2 TPR repeat TPR_2 PF07719.17 PRP78754.1 - 7.9e-08 31.9 18.6 2.2 8.6 0.0 9.3 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 PRP78754.1 - 2.2e-06 27.7 1.4 6.3 7.4 0.0 6.8 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP78754.1 - 3.7e-06 27.4 1.6 11 6.6 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat F-box-like PF12937.7 PRP78754.1 - 8.9e-06 25.5 0.7 2.6e-05 24.0 0.7 1.9 1 0 0 1 1 1 1 F-box-like TPR_8 PF13181.6 PRP78754.1 - 3.6e-05 23.6 6.3 1.1 9.6 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP78754.1 - 9.8e-05 22.0 10.4 3.3 7.7 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP78754.1 - 0.0013 19.4 5.5 1.2e+02 3.9 0.0 7.1 7 1 1 8 8 7 0 Tetratricopeptide repeat F-box PF00646.33 PRP78754.1 - 0.004 17.0 0.3 0.009 15.9 0.3 1.7 1 0 0 1 1 1 1 F-box domain TPR_10 PF13374.6 PRP78754.1 - 0.056 13.3 5.9 1 9.3 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP78754.1 - 0.067 13.5 10.1 12 6.3 0.1 6.4 6 3 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP78754.1 - 0.12 13.0 2.0 0.93 10.2 0.0 3.6 5 0 0 5 5 3 0 Tetratricopeptide repeat Spore_III_AB PF09548.10 PRP78754.1 - 0.23 11.6 5.9 0.35 11.0 0.0 3.6 5 0 0 5 5 5 0 Stage III sporulation protein AB (spore_III_AB) Ank_2 PF12796.7 PRP78755.1 - 2.9e-09 37.4 0.0 4.2e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78755.1 - 3.6e-07 30.6 0.0 0.00045 20.7 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP78755.1 - 1.9e-06 28.1 0.0 0.037 14.4 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78755.1 - 0.0034 17.8 0.0 1.7 9.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 PRP78755.1 - 0.022 15.2 0.0 5.4 7.6 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeat TruB_N PF01509.18 PRP78756.1 - 1.1e-22 81.0 0.0 5.3e-22 78.8 0.0 1.9 1 1 1 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PRP78756.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain DHHC PF01529.20 PRP78757.1 - 3.9e-33 114.4 12.3 3.9e-33 114.4 12.3 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase NAD_binding_1 PF00175.21 PRP78757.1 - 1.9e-14 54.3 0.0 3.7e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 PRP78757.1 - 4e-08 33.5 0.1 3e-07 30.7 0.0 2.0 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 PRP78757.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DUF2975 PF11188.8 PRP78757.1 - 0.022 14.6 0.5 0.022 14.6 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF5498 PF17602.2 PRP78757.1 - 0.14 12.7 0.0 0.46 11.0 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5498) DUF1272 PF06906.11 PRP78757.1 - 2.5 8.2 7.6 5.2 7.3 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF1134 PF06577.12 PRP78758.1 - 0.17 11.6 0.1 0.23 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) ECH_1 PF00378.20 PRP78759.1 - 1.1e-26 93.7 0.2 4.4e-26 91.7 0.2 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP78759.1 - 1e-09 38.3 0.1 2.6e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 PRP78759.1 - 0.26 11.2 0.9 10 6.0 0.5 2.2 1 1 1 2 2 2 0 Peptidase family S49 60KD_IMP PF02096.20 PRP78760.1 - 2e-16 60.3 1.6 3.6e-16 59.5 1.6 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein MAP17 PF15807.5 PRP78760.1 - 0.024 14.8 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Selenoprotein_S PF06936.11 PRP78760.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) TM231 PF10149.9 PRP78761.1 - 5.8e-57 193.3 8.3 1.1e-56 192.4 8.3 1.5 1 0 0 1 1 1 1 Transmembrane protein 231 ASH PF15780.5 PRP78761.1 - 3.6e-38 129.7 26.6 1.9e-06 28.0 0.2 14.7 15 0 0 15 15 15 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Glyco_hydro_43 PF04616.14 PRP78761.1 - 3.8e-36 124.9 3.7 7.8e-36 123.9 3.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Motile_Sperm PF00635.26 PRP78761.1 - 9.7e-18 64.0 15.5 0.0012 18.7 0.0 9.8 9 0 0 9 9 9 5 MSP (Major sperm protein) domain DUF1573 PF07610.11 PRP78761.1 - 7.5e-12 45.1 6.2 0.0014 18.6 0.6 8.4 10 1 0 10 10 8 2 Protein of unknown function (DUF1573) CH PF00307.31 PRP78761.1 - 2e-09 37.6 0.0 5.2e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain TMEM131_like PF12371.8 PRP78761.1 - 2.8e-07 30.7 18.8 0.052 13.8 0.4 8.0 8 0 0 8 8 7 3 Transmembrane protein 131-like FixG_C PF11614.8 PRP78761.1 - 0.00042 20.5 0.4 0.78 10.0 0.0 5.2 6 0 0 6 6 5 1 IG-like fold at C-terminal of FixG, putative oxidoreductase PapD-like PF14874.6 PRP78761.1 - 0.0005 20.2 8.1 0.062 13.5 0.3 6.2 7 0 0 7 7 7 1 Flagellar-associated PapD-like BrnA_antitoxin PF14384.6 PRP78761.1 - 0.0035 17.8 0.0 0.057 13.9 0.0 2.7 2 0 0 2 2 2 1 BrnA antitoxin of type II toxin-antitoxin system Transglut_C PF00927.22 PRP78761.1 - 0.0059 16.7 1.0 45 4.3 0.0 6.5 8 0 0 8 8 7 0 Transglutaminase family, C-terminal ig like domain GDE_N_bis PF14742.6 PRP78761.1 - 0.054 13.1 0.1 4.7 6.7 0.0 3.3 3 0 0 3 3 3 0 N-terminal domain of (some) glycogen debranching enzymes ApoB100_C PF12491.8 PRP78761.1 - 0.061 13.3 0.0 0.32 11.0 0.0 2.2 3 0 0 3 3 2 0 Apolipoprotein B100 C terminal MYCBPAP PF14646.6 PRP78761.1 - 0.09 11.7 0.2 0.69 8.8 0.0 2.5 3 0 0 3 3 3 0 MYCBP-associated protein family CAMSAP_CH PF11971.8 PRP78761.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain Arm PF00514.23 PRP78764.1 - 9.4e-10 38.2 7.0 0.00061 19.7 0.2 6.0 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PRP78764.1 - 0.0024 18.2 1.7 0.39 11.1 0.0 4.3 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 PRP78764.1 - 0.024 14.9 0.2 1.2 9.6 0.1 3.8 4 0 0 4 4 4 0 HEAT repeat Pkinase PF00069.25 PRP78766.1 - 9.2e-50 169.5 0.0 1.3e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78766.1 - 9.8e-26 90.6 0.0 1.6e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP78766.1 - 1.5e-05 25.1 0.0 9.7e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP78766.1 - 0.00019 20.8 0.0 0.00044 19.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_8 PF13188.7 PRP78766.1 - 0.00058 19.8 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain Piezo_RRas_bdg PF12166.8 PRP78767.1 - 3.9e-68 230.7 1.1 3.9e-68 230.7 1.1 1.8 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain Hemerythrin PF01814.23 PRP78768.1 - 4.6e-07 30.5 1.7 8.5e-07 29.7 1.7 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain U83 PF17465.2 PRP78768.1 - 0.075 13.2 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 Chemokine-like protein, HHV-6 U83 gene product G8 PF10162.9 PRP78768.1 - 0.15 12.1 1.3 1.5 8.9 0.4 2.8 1 1 2 3 3 3 0 G8 domain FDF PF09532.10 PRP78768.1 - 0.36 11.7 1.8 0.71 10.8 1.8 1.4 1 0 0 1 1 1 0 FDF domain X8 PF07983.13 PRP78769.1 - 4e-28 97.9 28.1 3.5e-09 37.2 4.2 3.9 3 0 0 3 3 3 3 X8 domain CBM_5_12_2 PF14600.6 PRP78769.1 - 3e-07 30.3 11.8 0.12 12.3 0.3 3.9 3 0 0 3 3 3 3 Cellulose-binding domain Cellulase PF00150.18 PRP78769.1 - 5.6e-07 29.3 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GlgS PF08971.11 PRP78769.1 - 2.3e-05 24.3 1.3 5.1 7.2 0.0 3.4 3 0 0 3 3 3 3 Glycogen synthesis protein TssC PF17541.2 PRP78769.1 - 0.0058 15.5 0.3 11 4.7 0.0 3.0 3 0 0 3 3 3 2 Type VI secretion system, TssC, VipB BCDHK_Adom3 PF10436.9 PRP78770.1 - 4.8e-45 153.3 0.2 6.6e-45 152.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 PRP78770.1 - 7.9e-11 42.5 0.0 1.6e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PRP78770.1 - 7.5e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1580 PF07618.11 PRP78770.1 - 0.052 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Laminin_G_3 PF13385.6 PRP78771.1 - 1.7e-38 132.1 3.3 7.2e-20 71.7 0.1 2.6 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily zf-C2HC_2 PF13913.6 PRP78771.1 - 1.4e-28 98.1 27.0 4.1e-09 36.1 0.2 5.9 6 0 0 6 6 6 4 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 PRP78771.1 - 2.8e-06 27.0 2.0 2.7 7.9 0.0 4.8 4 0 0 4 4 4 2 Rad50 zinc hook motif Toxin_R_bind_N PF07953.12 PRP78771.1 - 0.0051 16.6 0.4 1.2 8.8 0.4 2.6 2 1 0 2 2 2 1 Clostridium neurotoxin, N-terminal receptor binding zf_C2H2_10 PF18414.1 PRP78771.1 - 0.014 14.9 5.2 3.2 7.4 0.0 3.8 3 0 0 3 3 3 0 C2H2 type zinc-finger Laminin_G_2 PF02210.24 PRP78771.1 - 0.04 14.5 0.0 0.24 12.0 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain DUF5456 PF17539.2 PRP78771.1 - 0.36 10.7 2.4 24 4.7 0.0 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5456) FliC PF12445.8 PRP78771.1 - 0.83 10.0 4.9 6.3 7.1 5.0 2.5 2 0 0 2 2 2 0 Flagellin protein DUF3039 PF11238.8 PRP78771.1 - 2.7 7.8 7.9 8.6 6.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) zf-C2H2_4 PF13894.6 PRP78771.1 - 3.1 8.9 34.7 0.17 12.8 0.4 6.7 6 1 1 7 7 7 0 C2H2-type zinc finger Carb_bind PF10645.9 PRP78771.1 - 6.1 7.2 30.5 0.55 10.5 5.0 4.0 2 1 1 3 3 3 0 Carbohydrate binding ADK_lid PF05191.14 PRP78771.1 - 6.6 6.8 18.8 16 5.6 0.1 5.0 4 1 0 4 4 4 0 Adenylate kinase, active site lid GcpE PF04551.14 PRP78771.1 - 7.3 5.6 5.8 11 5.0 0.0 2.7 3 0 0 3 3 3 0 GcpE protein YhfH PF14149.6 PRP78771.1 - 8.2 6.5 8.9 27 4.9 0.1 4.3 4 0 0 4 4 4 0 YhfH-like protein NUDIX PF00293.28 PRP78772.1 - 1.7e-15 57.2 0.2 2.1e-15 56.9 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain DeoC PF01791.9 PRP78773.1 - 3.8e-12 46.3 0.1 6.6e-12 45.6 0.1 1.3 1 1 0 1 1 1 1 DeoC/LacD family aldolase Mago_nashi PF02792.14 PRP78774.1 - 3e-75 251.1 1.5 3.3e-75 251.0 1.5 1.0 1 0 0 1 1 1 1 Mago nashi protein RicinB_lectin_2 PF14200.6 PRP78777.1 - 1.1e-07 32.4 8.9 2.1e-07 31.6 0.3 3.2 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 PRP78777.1 - 8.6e-06 26.0 0.6 2.6e-05 24.5 0.1 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain START PF01852.19 PRP78778.1 - 6.8e-15 55.0 0.1 1.1e-14 54.3 0.1 1.3 1 0 0 1 1 1 1 START domain AATF-Che1 PF13339.6 PRP78778.1 - 0.15 12.7 6.6 0.38 11.4 6.6 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor PIN_8 PF18476.1 PRP78778.1 - 0.48 10.2 5.5 0.84 9.5 5.5 1.3 1 0 0 1 1 1 0 PIN like domain TFIIA PF03153.13 PRP78778.1 - 3.5 7.5 10.6 5.2 7.0 10.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 PRP78778.1 - 8.8 4.7 6.4 14 4.1 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 PRP78778.1 - 9.1 6.3 13.1 17 5.5 13.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Membr_traf_MHD PF10540.9 PRP78781.1 - 1.3e-07 32.0 3.8 0.0042 17.3 0.1 3.3 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 PRP78781.1 - 9.7e-06 24.4 1.1 2.1e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) DUF1682 PF07946.14 PRP78781.1 - 0.0056 15.9 6.0 0.012 14.8 6.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Maf1 PF09174.10 PRP78781.1 - 0.017 15.3 1.2 0.06 13.5 0.5 2.2 2 0 0 2 2 2 0 Maf1 regulator Peptidase_S49_N PF08496.10 PRP78781.1 - 2.6 8.1 9.5 0.36 10.9 5.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_L18_c PF14204.6 PRP78781.1 - 4.8 8.2 9.3 0.73 10.8 3.3 2.9 3 0 0 3 3 3 0 Ribosomal L18 C-terminal region Abhydrolase_6 PF12697.7 PRP78782.1 - 3.6e-15 57.2 0.2 2.6e-14 54.4 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP78782.1 - 3.8e-14 53.0 0.2 1.4e-13 51.1 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP78782.1 - 5.4e-09 35.7 0.0 1e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PRP78782.1 - 8.8e-08 32.2 0.1 4.6e-06 26.5 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 PRP78782.1 - 8.7e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 2 0 0 2 2 2 1 Putative esterase Thioesterase PF00975.20 PRP78782.1 - 4.7e-05 23.6 0.0 8.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 PRP78782.1 - 0.016 14.1 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydro_lipase PF04083.16 PRP78782.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.25 PRP78782.1 - 0.065 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 PRP78782.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 PRP78782.1 - 0.1 11.6 0.1 0.16 10.9 0.1 1.3 1 1 0 1 1 1 0 Chlorophyllase DUF2974 PF11187.8 PRP78782.1 - 0.17 11.4 0.0 0.81 9.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) DLH PF01738.18 PRP78782.1 - 0.2 11.2 0.0 4.6 6.7 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Pkinase_Tyr PF07714.17 PRP78783.1 - 1.3e-32 113.1 0.9 2.4e-32 112.2 0.9 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78783.1 - 4.3e-30 105.0 1.8 6.7e-30 104.3 1.8 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP78783.1 - 2.7e-09 37.4 6.5 6.2e-09 36.2 6.5 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif ASFV_J13L PF05568.11 PRP78783.1 - 0.016 14.9 0.2 0.034 13.9 0.2 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Pkinase_Tyr PF07714.17 PRP78784.1 - 4.7e-30 104.7 0.3 8.2e-30 103.9 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Grg1 PF11034.8 PRP78784.1 - 5e-30 103.5 9.6 1e-29 102.5 9.6 1.6 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Pkinase PF00069.25 PRP78784.1 - 3.6e-29 101.9 1.0 5.6e-29 101.3 1.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP78784.1 - 4.4e-10 39.9 5.4 1.4e-09 38.3 5.4 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif ASFV_J13L PF05568.11 PRP78784.1 - 0.037 13.8 1.9 0.056 13.2 0.1 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein PIP49_C PF12260.8 PRP78784.1 - 0.047 13.3 0.0 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 TMEM154 PF15102.6 PRP78784.1 - 0.41 10.6 0.0 0.41 10.6 0.0 2.9 4 0 0 4 4 4 0 TMEM154 protein family Glycophorin_A PF01102.18 PRP78784.1 - 1.8 8.8 4.9 0.96 9.7 0.1 2.5 2 0 0 2 2 2 0 Glycophorin A DnaJ PF00226.31 PRP78786.1 - 8.7e-26 89.8 4.2 1.8e-25 88.8 1.2 3.1 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 PRP78786.1 - 0.0031 17.8 14.2 0.17 12.2 7.6 3.0 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PRP78786.1 - 0.016 16.0 7.6 0.049 14.5 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger C1_4 PF07975.12 PRP78786.1 - 0.11 12.8 0.7 7.4 6.9 0.2 2.8 2 0 0 2 2 2 0 TFIIH C1-like domain zf-met PF12874.7 PRP78786.1 - 0.29 11.6 9.7 2.1 8.9 2.9 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PRP78786.1 - 1 9.8 15.7 0.12 12.7 0.6 3.8 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 PRP78786.1 - 1.2 9.2 5.7 0.35 10.9 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PRP78786.1 - 1.5 9.4 5.9 0.21 12.1 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Mito_fiss_reg PF05308.11 PRP78787.1 - 0.0079 16.3 4.3 0.016 15.3 4.3 1.5 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF2407 PF10302.9 PRP78787.1 - 0.12 12.9 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Histone PF00125.24 PRP78788.1 - 3.6e-52 176.2 2.9 4e-52 176.0 2.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PRP78788.1 - 6.5e-05 23.0 1.1 9.2e-05 22.5 0.1 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 PRP78788.1 - 0.00018 22.1 0.9 0.00021 21.9 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PRP78788.1 - 0.00034 21.0 0.0 0.00054 20.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 PRP78788.1 - 0.028 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 PRP78788.1 - 0.092 13.0 0.6 0.16 12.3 0.1 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SH3_9 PF14604.6 PRP78789.1 - 8.6e-24 83.2 3.3 5.5e-13 48.5 0.2 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PRP78789.1 - 2.4e-20 71.9 1.9 6.5e-11 41.7 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 PRP78789.1 - 1.1e-16 60.3 0.1 3.2e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_16 PF18348.1 PRP78789.1 - 0.17 11.7 0.2 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Ras PF00071.22 PRP78790.1 - 1e-49 168.2 0.0 1.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP78790.1 - 8.3e-17 61.5 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP78790.1 - 1.4e-05 24.7 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP78790.1 - 0.00044 20.2 0.0 0.86 9.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP78790.1 - 0.00091 18.8 0.0 0.0036 16.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PRP78790.1 - 0.0018 17.9 0.0 0.0029 17.1 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 PRP78790.1 - 0.0043 17.1 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase CH PF00307.31 PRP78791.1 - 1.5e-46 157.1 1.5 2e-27 95.5 0.1 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP78791.1 - 1.1e-12 47.6 0.6 4.1e-11 42.6 0.1 2.4 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_6 PF13405.6 PRP78791.1 - 2.4e-07 30.1 0.1 1.1e-06 28.1 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 PRP78791.1 - 4.8e-06 25.7 0.1 1.9e-05 23.9 0.1 2.1 1 0 0 1 1 1 1 EF hand Spectrin PF00435.21 PRP78791.1 - 1.1e-05 25.8 23.5 0.00014 22.3 1.5 3.7 4 1 1 5 5 4 2 Spectrin repeat EFhand_Ca_insen PF08726.10 PRP78791.1 - 2e-05 24.6 2.3 0.0011 19.0 0.2 3.7 3 0 0 3 3 3 1 Ca2+ insensitive EF hand EF-hand_7 PF13499.6 PRP78791.1 - 0.001 19.5 0.2 0.0044 17.4 0.2 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP78791.1 - 0.027 14.0 0.5 0.13 11.8 0.1 2.4 2 0 0 2 2 2 0 EF hand DUF1247 PF06851.11 PRP78791.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) EF-hand_8 PF13833.6 PRP78791.1 - 0.12 12.2 0.1 0.67 9.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Bap31_Bap29_C PF18035.1 PRP78791.1 - 1.2 9.2 6.3 26 4.9 6.3 2.9 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain HrpB7 PF09486.10 PRP78791.1 - 6.2 7.2 12.5 0.064 13.7 2.9 2.6 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Pkinase_Tyr PF07714.17 PRP78792.1 - 2.7e-73 246.5 0.0 4.4e-73 245.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78792.1 - 4.1e-52 177.2 0.0 6.8e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP78792.1 - 1.9e-37 126.8 84.4 6.1e-05 22.7 3.3 15.0 8 3 5 15 15 15 13 Leucine rich repeat LRR_4 PF12799.7 PRP78792.1 - 9.7e-30 102.1 90.4 8.1e-06 26.1 0.3 16.4 11 3 9 20 20 20 11 Leucine Rich repeats (2 copies) DUF2373 PF10180.9 PRP78792.1 - 7e-18 64.2 0.7 1.7e-17 63.0 0.7 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) SET PF00856.28 PRP78792.1 - 3.3e-11 43.8 0.0 3.3e-11 43.8 0.0 3.0 2 1 0 2 2 1 1 SET domain ArAE_2 PF10334.9 PRP78792.1 - 4.8e-06 26.6 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 Kinase-like PF14531.6 PRP78792.1 - 8.5e-06 25.3 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 PRP78792.1 - 2.8e-05 23.8 55.8 1.1 9.5 0.1 16.0 17 0 0 17 17 17 2 Leucine Rich repeat Kdo PF06293.14 PRP78792.1 - 0.00014 21.3 0.4 0.00014 21.3 0.4 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Amnionless PF14828.6 PRP78792.1 - 0.00044 19.2 0.2 0.00077 18.4 0.2 1.3 1 0 0 1 1 1 1 Amnionless zf-MYND PF01753.18 PRP78792.1 - 0.0019 18.3 3.2 0.0019 18.3 3.2 2.9 3 0 0 3 3 3 1 MYND finger EphA2_TM PF14575.6 PRP78792.1 - 0.23 12.4 0.4 0.85 10.5 0.4 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_1 PF00560.33 PRP78792.1 - 0.5 11.1 61.7 6.9 7.6 0.2 18.7 22 1 0 22 22 19 0 Leucine Rich Repeat DUF262 PF03235.14 PRP78792.1 - 2.4 8.3 10.5 5.4 7.1 10.5 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF262 VPS9 PF02204.18 PRP78793.1 - 7.5e-16 58.2 0.2 8.4e-15 54.9 0.1 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.20 PRP78793.1 - 6.5e-14 50.9 24.6 0.002 17.9 0.1 7.3 7 0 0 7 7 7 4 MORN repeat SH2 PF00017.24 PRP78793.1 - 1.9e-11 43.9 0.0 0.00031 20.8 0.0 2.7 2 0 0 2 2 2 2 SH2 domain RPW8 PF05659.11 PRP78793.1 - 0.052 13.2 6.1 0.14 11.9 6.1 1.7 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 AAA_12 PF13087.6 PRP78794.1 - 6.3e-12 45.5 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PRP78794.1 - 0.0054 17.0 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP78794.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 PRP78794.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RhoGEF PF00621.20 PRP78795.1 - 3.6e-41 141.4 1.3 1.5e-40 139.4 0.2 2.8 2 0 0 2 2 2 1 RhoGEF domain Ank_4 PF13637.6 PRP78795.1 - 8.1e-12 45.4 0.5 0.0028 18.2 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP78795.1 - 7.1e-11 42.5 0.0 0.00056 20.5 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP78795.1 - 1e-09 38.5 0.1 0.00012 22.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP78795.1 - 4.8e-06 26.4 0.3 9.9e-06 25.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like Ank_3 PF13606.6 PRP78795.1 - 1.4e-05 25.0 0.0 4.7 8.1 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat F-box PF00646.33 PRP78795.1 - 0.00013 21.7 0.4 0.00033 20.5 0.4 1.7 1 0 0 1 1 1 1 F-box domain IQ PF00612.27 PRP78795.1 - 0.013 15.2 0.0 0.038 13.8 0.0 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ank PF00023.30 PRP78795.1 - 0.015 15.7 0.1 12 6.5 0.0 4.0 3 0 0 3 3 3 0 Ankyrin repeat DUF1275 PF06912.11 PRP78796.1 - 4.5e-26 92.0 17.3 4.5e-26 92.0 17.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1275) Ctr PF04145.15 PRP78796.1 - 8.9e-23 81.5 10.4 8.9e-23 81.5 10.4 3.2 3 1 0 3 3 3 1 Ctr copper transporter family DUF4131 PF13567.6 PRP78796.1 - 0.061 13.0 2.6 0.23 11.1 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Motile_Sperm PF00635.26 PRP78796.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain NADH_4Fe-4S PF10589.9 PRP78796.1 - 0.49 10.5 6.4 0.33 11.0 1.6 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region RasGAP PF00616.19 PRP78797.1 - 2.8e-17 63.1 0.1 9.6e-13 48.3 0.0 3.2 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase SKA2 PF16740.5 PRP78797.1 - 0.008 16.0 1.2 0.024 14.4 1.2 1.9 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF4845 PF16137.5 PRP78797.1 - 0.17 12.8 0.6 0.67 10.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4845) DUF641 PF04859.12 PRP78797.1 - 0.81 10.0 5.3 0.44 10.9 2.9 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 PRP78797.1 - 0.95 10.1 7.4 0.52 11.0 4.3 2.2 2 0 0 2 2 2 0 SlyX DUF16 PF01519.16 PRP78797.1 - 4.6 7.8 10.5 1.1 9.8 5.5 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF2385 PF09539.10 PRP78798.1 - 0.0092 16.5 0.3 0.0099 16.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2385) Tox-GHH PF15636.6 PRP78798.1 - 0.022 14.7 1.8 0.026 14.5 1.8 1.1 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Pyr_redox_2 PF07992.14 PRP78800.1 - 2.3e-43 148.5 0.2 2.6e-43 148.3 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP78800.1 - 2e-21 76.6 0.0 1.1e-17 64.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP78800.1 - 1.3e-17 64.1 0.9 1.3e-16 60.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PRP78800.1 - 1.8e-06 27.4 1.3 0.016 14.5 0.0 3.2 2 1 1 3 3 3 2 Thi4 family GIDA PF01134.22 PRP78800.1 - 1.3e-05 24.5 1.9 0.1 11.6 0.1 3.6 3 1 1 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 PRP78800.1 - 3.5e-05 23.1 2.1 0.025 13.7 0.3 2.7 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 PRP78800.1 - 5.4e-05 22.7 2.3 0.082 12.2 0.2 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP78800.1 - 0.00026 21.2 0.1 0.0047 17.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 PRP78800.1 - 0.0004 19.6 0.0 0.058 12.5 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 PRP78800.1 - 0.0037 16.9 2.6 4.2 6.9 0.6 3.5 3 1 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP78800.1 - 0.0046 15.7 0.3 0.091 11.4 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 PRP78800.1 - 0.0062 15.8 0.5 1.7 7.8 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.21 PRP78800.1 - 0.042 13.1 0.2 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 PRP78800.1 - 0.066 13.7 0.1 0.39 11.2 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Guanylate_cyc PF00211.20 PRP78802.1 - 2.4e-53 180.5 0.0 3.7e-31 108.2 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain MOR2-PAG1_N PF14222.6 PRP78803.1 - 8.1e-16 58.1 0.5 8.1e-16 58.1 0.5 1.9 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.6 PRP78803.1 - 9e-05 20.3 0.1 0.00014 19.7 0.1 1.2 1 0 0 1 1 1 1 Cell morphogenesis central region V-ATPase_H_N PF03224.14 PRP78803.1 - 0.0024 17.2 0.8 0.0069 15.7 0.1 2.2 2 0 0 2 2 2 1 V-ATPase subunit H Histone PF00125.24 PRP78804.1 - 4.9e-27 94.9 1.1 5.7e-27 94.7 1.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PRP78804.1 - 0.01 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Cytochrom_B558a PF05038.13 PRP78805.1 - 0.0025 17.4 0.7 0.0025 17.4 0.7 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit YhhN PF07947.14 PRP78805.1 - 0.95 9.0 10.7 0.045 13.4 1.8 2.1 1 1 1 2 2 2 0 YhhN family DUF4156 PF13698.6 PRP78806.1 - 5.2e-06 26.7 0.0 17 5.8 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4156) DUF1570 PF07607.11 PRP78806.1 - 0.00034 20.9 1.5 11 6.4 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1570) IncF PF17626.2 PRP78806.1 - 0.0043 17.4 3.3 69 3.9 0.2 4.2 4 0 0 4 4 4 0 Inclusion membrane protein F CD34_antigen PF06365.12 PRP78806.1 - 0.014 15.0 1.6 13 5.3 0.1 3.1 3 0 0 3 3 3 0 CD34/Podocalyxin family DUF2684 PF10885.8 PRP78806.1 - 0.036 14.2 5.8 4.3 7.5 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2684) Comm PF15957.5 PRP78806.1 - 0.13 12.6 0.9 16 5.8 0.3 3.0 3 0 0 3 3 3 0 Commissureless DUF2218 PF09981.9 PRP78806.1 - 0.17 12.3 0.1 35 4.9 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2218) Annexin_like PF18411.1 PRP78806.1 - 0.2 12.0 1.0 78 3.6 0.0 3.3 3 0 0 3 3 3 0 Annexin-like domain Cpta_toxin PF07254.12 PRP78806.1 - 0.46 10.5 5.9 9.1 6.3 0.2 3.4 3 0 0 3 3 3 0 Membrane-bound toxin component of toxin-antitoxin system ExoD PF06055.12 PRP78806.1 - 3.5 7.0 8.0 36 3.7 0.1 3.3 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD EPTP PF03736.17 PRP78806.1 - 4.5 7.4 6.7 1.1e+02 2.9 0.2 3.7 3 0 0 3 3 3 0 EPTP domain SNF2_N PF00176.23 PRP78807.1 - 1.4e-59 201.6 3.7 8.7e-59 199.0 3.7 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP78807.1 - 2.1e-17 63.4 0.0 1.3e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78807.1 - 3e-09 37.1 0.4 1e-08 35.4 0.1 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 PRP78807.1 - 7.9e-07 28.9 5.6 1.4e-06 28.1 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 PRP78807.1 - 1.5e-05 24.8 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 PRP78807.1 - 4.8e-05 23.6 7.7 8.5e-05 22.8 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP78807.1 - 5.2e-05 23.0 5.3 0.00011 22.0 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP78807.1 - 5.6e-05 23.0 5.7 9.9e-05 22.2 5.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain SWI2_SNF2 PF18766.1 PRP78807.1 - 0.00047 19.9 0.2 0.00085 19.0 0.2 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase zf-C3HC4_3 PF13920.6 PRP78807.1 - 0.00058 19.7 6.1 0.001 18.9 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP78807.1 - 0.001 19.0 3.5 0.0021 18.0 3.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PRP78807.1 - 0.0084 16.2 5.2 0.021 14.9 5.2 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PRP78807.1 - 0.023 14.5 5.4 0.047 13.6 5.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 PRP78807.1 - 0.098 12.5 0.7 0.3 10.9 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 PRP78807.1 - 0.17 12.2 6.2 0.37 11.1 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 PRP78807.1 - 0.86 9.5 7.5 1.7 8.5 7.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 PRP78807.1 - 0.9 9.2 7.5 1.7 8.3 7.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type UPF0515 PF15135.6 PRP78807.1 - 4.4 6.6 7.7 2 7.7 0.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein UPF0515 zf-MIZ PF02891.20 PRP78807.1 - 6.5 6.6 6.1 16 5.3 6.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Ufd2P_core PF10408.9 PRP78808.1 - 2.6e-170 568.1 15.7 3.5e-170 567.7 15.7 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 PRP78808.1 - 1.3e-26 92.6 0.6 5.7e-26 90.5 0.6 2.2 1 0 0 1 1 1 1 U-box domain FlaC_arch PF05377.11 PRP78808.1 - 0.48 10.9 2.6 1.7 9.1 0.1 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Pro-kuma_activ PF09286.11 PRP78809.1 - 2.1e-30 105.9 0.0 4.1e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP78809.1 - 0.00014 21.3 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Pkinase_fungal PF17667.1 PRP78809.1 - 0.0096 14.7 4.6 0.015 14.1 4.6 1.2 1 0 0 1 1 1 1 Fungal protein kinase MRNIP PF15749.5 PRP78809.1 - 0.19 12.5 2.9 0.38 11.5 2.9 1.4 1 0 0 1 1 1 0 MRN-interacting protein Ribosomal_L14e PF01929.17 PRP78810.1 - 1.2e-19 70.5 0.3 1.7e-19 70.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 PRP78810.1 - 0.0054 16.6 0.4 0.0098 15.8 0.4 1.4 1 0 0 1 1 1 1 KOW motif rRNA_proc-arch PF13234.6 PRP78810.1 - 0.072 13.0 0.4 0.13 12.2 0.4 1.6 1 1 0 1 1 1 0 rRNA-processing arch domain Ank_2 PF12796.7 PRP78811.1 - 1.4e-33 115.4 0.0 8.8e-16 58.3 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78811.1 - 6.3e-27 93.6 0.4 2e-08 34.6 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP78811.1 - 7.4e-25 86.3 0.1 4.9e-05 23.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 PRP78811.1 - 2.8e-24 82.5 0.3 0.00032 20.9 0.0 6.5 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 PRP78811.1 - 2.8e-24 84.9 0.9 6.9e-08 32.6 0.0 4.2 3 2 1 4 4 4 3 Ankyrin repeats (many copies) DUF410 PF04190.13 PRP78811.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) DUF3447 PF11929.8 PRP78811.1 - 0.12 12.3 0.0 2.5 8.1 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) Sec23_trunk PF04811.15 PRP78812.1 - 1.6e-13 50.8 0.0 3.2e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 PRP78812.1 - 5.8e-12 45.3 0.1 1.5e-11 44.0 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 PRP78812.1 - 1.7e-08 35.1 0.0 4.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 PRP78812.1 - 4.4e-07 29.8 0.5 8.6e-07 28.9 0.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Pkinase_Tyr PF07714.17 PRP78813.1 - 5.1e-22 78.4 0.2 1.4e-21 77.0 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78813.1 - 5e-13 49.0 0.3 1.1e-12 47.9 0.3 1.5 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP78813.1 - 2.9e-08 33.3 19.3 0.0055 16.4 7.2 4.2 3 0 0 3 3 3 3 Leucine rich repeat GPS PF01825.21 PRP78813.1 - 1.6e-06 28.6 5.8 4.9e-06 27.0 5.8 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP78813.1 - 5.9e-05 23.4 33.3 0.0027 18.1 4.0 6.1 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP78813.1 - 0.0042 16.4 0.1 0.0072 15.7 0.1 1.3 1 0 0 1 1 1 1 Kinase-like LRR_1 PF00560.33 PRP78813.1 - 0.53 11.0 18.4 2.4 9.0 0.1 6.9 8 0 0 8 8 8 0 Leucine Rich Repeat RasGEF PF00617.19 PRP78814.1 - 3.3e-37 128.4 0.1 4.8e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP78815.1 - 0.022 15.0 0.2 0.082 13.2 0.2 2.0 1 0 0 1 1 1 0 RasGEF N-terminal motif IQ PF00612.27 PRP78815.1 - 0.023 14.5 10.3 0.079 12.8 1.7 3.2 3 0 0 3 3 3 0 IQ calmodulin-binding motif PH PF00169.29 PRP78815.1 - 0.063 13.8 0.0 0.27 11.8 0.0 2.1 1 1 0 1 1 1 0 PH domain EF-hand_8 PF13833.6 PRP78816.1 - 1e-06 28.5 0.1 1.5e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP78816.1 - 2.6e-06 26.6 0.2 0.00037 19.8 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP78816.1 - 3e-06 26.7 0.5 0.075 13.0 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PRP78816.1 - 6.7e-06 26.5 0.2 1.1e-05 25.8 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP78816.1 - 0.017 14.6 0.8 0.33 10.5 0.1 2.3 2 0 0 2 2 2 0 EF hand IlvGEDA_leader PF08046.11 PRP78816.1 - 0.23 10.9 0.4 0.39 10.2 0.4 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide U-box PF04564.15 PRP78817.1 - 3.3e-17 62.4 0.0 7.8e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain UEV PF05743.13 PRP78817.1 - 3.3e-11 43.1 0.0 8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 UEV domain SAM_1 PF00536.30 PRP78817.1 - 1.6e-08 34.9 0.2 0.0002 21.7 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) zf-Nse PF11789.8 PRP78817.1 - 5.4e-07 29.3 0.0 6.6e-05 22.7 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit SAM_2 PF07647.17 PRP78817.1 - 7.7e-05 22.7 0.3 0.0074 16.4 0.1 2.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MCM3AP_GANP PF16769.5 PRP78817.1 - 0.0064 14.8 4.5 0.01 14.2 4.5 1.2 1 0 0 1 1 1 1 MCM3AP domain of GANP SAM_PNT PF02198.16 PRP78817.1 - 0.049 13.6 0.1 0.55 10.2 0.0 2.4 1 1 1 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 PRP78817.1 - 0.082 12.7 0.2 4 7.3 0.0 2.9 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) zf-NOSIP PF15906.5 PRP78817.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF724 PF05266.14 PRP78817.1 - 0.34 10.7 6.3 0.58 10.0 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) GPS2_interact PF15784.5 PRP78817.1 - 0.53 10.8 5.3 1.2 9.6 5.3 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain FPP PF05911.11 PRP78819.1 - 1.2e-05 23.8 3.9 1.6e-05 23.3 3.9 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil WH2 PF02205.20 PRP78819.1 - 5.5e-05 22.9 0.0 0.00021 21.0 0.0 2.0 2 0 0 2 2 2 1 WH2 motif PBD PF00786.28 PRP78819.1 - 0.011 16.1 0.2 0.053 13.9 0.0 2.4 2 0 0 2 2 2 0 P21-Rho-binding domain TssO PF17561.2 PRP78819.1 - 0.11 12.6 0.3 0.11 12.6 0.3 2.7 2 1 1 3 3 3 0 Type VI secretion system, TssO GAS PF13851.6 PRP78819.1 - 0.11 11.8 17.3 1.7 8.0 5.7 2.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 PRP78819.1 - 0.17 12.0 14.4 0.13 12.4 2.8 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Cnn_1N PF07989.11 PRP78819.1 - 0.36 11.0 10.8 21 5.4 5.6 3.8 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 PRP78819.1 - 0.94 9.5 8.9 0.4 10.7 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FUSC PF04632.12 PRP78819.1 - 1.7 7.1 3.5 2.6 6.5 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 PRP78819.1 - 1.9 8.9 15.7 0.31 11.5 11.3 1.8 2 0 0 2 2 2 0 Fez1 Tup_N PF08581.10 PRP78819.1 - 2 8.8 8.7 1.8 8.9 0.7 3.9 2 1 1 4 4 4 0 Tup N-terminal Dzip-like_N PF13815.6 PRP78819.1 - 3.4 7.7 7.2 3.7 7.5 0.6 2.6 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF4071 PF13281.6 PRP78819.1 - 4.5 6.2 8.0 12 4.8 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4071) DivIC PF04977.15 PRP78819.1 - 5.7 6.8 13.0 11 5.8 3.4 3.3 2 1 1 3 3 3 0 Septum formation initiator Rho_Binding PF08912.11 PRP78819.1 - 5.9 7.8 16.3 0.25 12.2 1.3 3.1 3 0 0 3 3 2 0 Rho Binding GrpE PF01025.19 PRP78819.1 - 7.7 6.1 21.5 0.66 9.6 1.8 3.4 4 0 0 4 4 4 0 GrpE Cupin_2 PF07883.11 PRP78820.1 - 3.3e-11 42.8 0.1 4.7e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 PRP78820.1 - 1.5e-07 31.0 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 PRP78820.1 - 2.2e-05 24.4 0.0 2.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain EutQ PF06249.12 PRP78820.1 - 0.00028 20.7 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ CENP-C_C PF11699.8 PRP78820.1 - 0.00064 19.9 0.0 0.00092 19.4 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_6 PF12852.7 PRP78820.1 - 0.0022 17.8 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding_2 PF14525.6 PRP78820.1 - 0.059 13.1 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 AraC-binding-like domain Ectoine_synth PF06339.12 PRP78820.1 - 0.15 12.2 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Ectoine synthase Amidohydro_1 PF01979.20 PRP78821.1 - 2.9e-74 250.4 0.0 3.9e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PRP78821.1 - 6e-14 52.4 0.0 1.2e-10 41.5 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 PRP78821.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase HEAT PF02985.22 PRP78822.1 - 1.3e-15 56.2 5.3 0.0037 17.4 0.0 8.6 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 PRP78822.1 - 2.4e-12 47.1 0.5 3.1e-06 27.6 0.0 7.0 6 1 1 7 7 7 1 HEAT-like repeat IBN_N PF03810.19 PRP78822.1 - 5.1e-08 32.7 0.6 2.8e-07 30.3 0.0 2.6 3 0 0 3 3 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 PRP78822.1 - 8e-07 28.0 0.3 0.39 9.2 0.0 3.4 3 0 0 3 3 3 3 Adaptin N terminal region DUF3385 PF11865.8 PRP78822.1 - 2.4e-05 24.3 0.0 3.2 7.6 0.0 4.5 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) MMS19_C PF12460.8 PRP78822.1 - 4e-05 22.9 0.1 0.68 9.0 0.0 3.8 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal Xpo1 PF08389.12 PRP78822.1 - 0.00014 22.0 0.1 1.1 9.3 0.0 3.9 1 1 2 3 3 3 2 Exportin 1-like protein HEAT_2 PF13646.6 PRP78822.1 - 0.00014 22.2 0.1 4.2 7.8 0.0 5.1 4 2 1 5 5 5 1 HEAT repeats Arm PF00514.23 PRP78822.1 - 0.0011 18.9 5.7 0.017 15.2 0.1 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 PRP78822.1 - 0.0071 16.9 0.4 3.9 8.2 0.0 4.3 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 PRP78822.1 - 0.02 14.5 0.0 8.5 5.9 0.0 3.3 2 2 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Ecm29 PF13001.7 PRP78822.1 - 0.039 12.6 0.1 2 7.0 0.0 3.0 3 1 0 3 3 3 0 Proteasome stabiliser Cnd3 PF12719.7 PRP78822.1 - 0.083 12.1 0.1 0.6 9.3 0.1 2.5 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain MetOD1 PF18546.1 PRP78822.1 - 0.14 12.2 0.1 1.8 8.5 0.0 2.8 2 0 0 2 2 2 0 Metanogen output domain 1 MMPL PF03176.15 PRP78823.1 - 0.086 11.7 4.7 0.18 10.7 4.7 1.5 1 0 0 1 1 1 0 MMPL family DUF948 PF06103.11 PRP78823.1 - 9.2 6.6 9.0 38 4.6 9.0 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RIC1 PF07064.13 PRP78824.1 - 1.3e-57 195.1 0.2 2.5e-57 194.2 0.2 1.4 1 0 0 1 1 1 1 RIC1 EF-hand_1 PF00036.32 PRP78824.1 - 1.5e-12 46.1 5.0 2.5e-06 26.6 0.5 3.3 4 0 0 4 4 3 2 EF hand EF-hand_7 PF13499.6 PRP78824.1 - 2.2e-12 47.2 1.0 1.2e-11 44.9 0.5 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP78824.1 - 8.6e-12 44.0 0.9 4.8e-06 26.1 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP78824.1 - 2.9e-10 39.2 1.0 0.00077 18.8 0.0 2.9 2 0 0 2 2 2 2 EF hand zf-RING_2 PF13639.6 PRP78824.1 - 1.1e-08 35.3 30.5 1.6e-08 34.8 8.6 3.1 3 0 0 3 3 3 2 Ring finger domain zf-RING_11 PF17123.5 PRP78824.1 - 2.5e-08 33.5 6.6 2.5e-08 33.5 6.6 2.9 3 0 0 3 3 3 1 RING-like zinc finger ANAPC4_WD40 PF12894.7 PRP78824.1 - 4e-07 30.2 0.5 0.039 14.2 0.1 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 PRP78824.1 - 2.8e-06 27.5 4.4 2.8e-06 27.5 4.4 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain EF-hand_8 PF13833.6 PRP78824.1 - 4.4e-06 26.4 0.7 4.8e-05 23.1 0.1 2.8 1 1 1 2 2 2 2 EF-hand domain pair zf-C3HC4_3 PF13920.6 PRP78824.1 - 5.7e-06 26.1 8.5 5.7e-06 26.1 8.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP78824.1 - 6.7e-05 22.7 24.7 0.00014 21.7 7.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP78824.1 - 0.00013 21.8 7.6 0.00013 21.8 7.6 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PRP78824.1 - 0.0012 18.7 24.9 0.0027 17.5 7.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP78824.1 - 0.004 17.1 23.0 0.08 12.9 8.2 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-ANAPC11 PF12861.7 PRP78824.1 - 0.0091 16.0 2.1 0.0091 16.0 2.1 2.5 3 0 0 3 3 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PRP78824.1 - 0.076 13.2 5.4 0.028 14.6 1.4 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain IKI3 PF04762.12 PRP78824.1 - 0.088 10.8 0.0 0.2 9.6 0.0 1.5 1 0 0 1 1 1 0 IKI3 family RINGv PF12906.7 PRP78824.1 - 0.22 11.7 8.3 0.66 10.1 8.3 1.8 1 0 0 1 1 1 0 RING-variant domain DUF3918 PF13056.6 PRP78824.1 - 0.25 11.0 0.8 0.59 9.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) WD40 PF00400.32 PRP78824.1 - 0.46 11.5 7.8 7.9 7.5 0.2 4.8 5 0 0 5 5 3 0 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 PRP78824.1 - 0.75 9.9 22.2 0.071 13.1 7.9 2.8 2 0 0 2 2 2 0 RING-type zinc-finger TIG PF01833.24 PRP78826.1 - 9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 IPT/TIG domain Cdh1_DBD_1 PF18196.1 PRP78826.1 - 0.45 10.8 2.0 3.7 7.9 2.4 2.1 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Homeodomain PF00046.29 PRP78827.1 - 5e-16 58.3 5.1 9.5e-16 57.4 5.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP78827.1 - 0.04 13.8 2.8 0.04 13.8 2.8 2.4 2 1 0 2 2 2 0 Homeobox KN domain 4F5 PF04419.14 PRP78828.1 - 2.3e-05 25.2 3.9 2.3e-05 25.2 3.9 2.5 1 1 1 2 2 2 1 4F5 protein family GRIM-19 PF06212.12 PRP78829.1 - 3.3e-24 85.3 0.0 4.6e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 GRIM-19 protein Got1 PF04178.12 PRP78830.1 - 1.9e-16 60.5 13.9 2.3e-16 60.2 13.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PI-PLC-X PF00388.19 PRP78831.1 - 4e-05 23.2 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain CAP59_mtransfer PF11735.8 PRP78832.1 - 1.9e-52 178.3 0.0 2.5e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ig_2 PF13895.6 PRP78832.1 - 0.041 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Methyltransf_8 PF05148.15 PRP78834.1 - 5.3e-84 281.5 0.0 6.7e-84 281.1 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 PRP78834.1 - 3.5e-05 24.4 0.0 0.00031 21.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP78834.1 - 5e-05 22.9 0.1 0.0015 18.1 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PRP78834.1 - 0.00074 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PRP78834.1 - 0.001 19.7 0.0 0.044 14.5 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP78834.1 - 0.0053 16.6 0.1 0.47 10.2 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Stn1 PF10451.9 PRP78834.1 - 0.74 8.7 5.0 1.2 8.0 5.0 1.4 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Ndc1_Nup PF09531.10 PRP78834.1 - 2 7.0 10.5 2.5 6.7 10.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 PRP78834.1 - 2.7 6.5 13.4 4.1 5.9 13.4 1.3 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.17 PRP78834.1 - 8.8 5.0 15.4 13 4.4 15.4 1.2 1 0 0 1 1 1 0 Presenilin Ras PF00071.22 PRP78835.1 - 2.9e-59 199.3 0.3 4.2e-59 198.8 0.3 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP78835.1 - 1.1e-32 112.8 0.1 2.2e-32 111.8 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP78835.1 - 3.3e-14 52.7 0.1 4.3e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP78835.1 - 4.6e-08 33.1 2.7 1.5e-07 31.5 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP78835.1 - 4.5e-06 26.7 0.2 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP78835.1 - 3.1e-05 23.6 0.2 0.00016 21.3 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP78835.1 - 0.00011 21.7 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 PRP78835.1 - 0.00022 21.5 0.1 0.00096 19.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.18 PRP78835.1 - 0.00063 19.3 0.8 0.56 9.7 0.0 2.6 2 1 1 3 3 3 2 Ferrous iron transport protein B PduV-EutP PF10662.9 PRP78835.1 - 0.0042 16.8 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 PRP78835.1 - 0.0087 15.5 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein SRPRB PF09439.10 PRP78835.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TPP_enzyme_M PF00205.22 PRP78835.1 - 0.032 14.0 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain AAA_16 PF13191.6 PRP78835.1 - 0.035 14.5 0.1 0.059 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 PRP78835.1 - 0.043 13.0 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 PRP78835.1 - 0.044 13.3 0.0 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 PRP78835.1 - 0.057 13.9 0.3 0.11 13.0 0.2 1.8 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 PRP78835.1 - 0.057 13.1 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PRP78835.1 - 0.078 13.0 0.1 0.3 11.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 PRP78835.1 - 0.13 12.2 0.0 1 9.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 PRP78835.1 - 0.15 12.1 0.0 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Methyltransf_11 PF08241.12 PRP78837.1 - 6.8e-16 58.7 0.0 1.2e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP78837.1 - 5.1e-14 52.7 0.0 1.3e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP78837.1 - 2e-08 34.2 0.0 2.9e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP78837.1 - 6.2e-08 33.3 0.0 1.1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP78837.1 - 2.8e-07 30.1 0.0 3.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PRP78837.1 - 2.9e-05 23.9 0.0 0.00015 21.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PRP78837.1 - 5.3e-05 23.2 0.0 9.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.19 PRP78837.1 - 0.0036 17.1 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 PRP78837.1 - 0.024 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase NNMT_PNMT_TEMT PF01234.17 PRP78837.1 - 0.07 12.3 0.0 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DUF938 PF06080.12 PRP78837.1 - 0.09 12.5 0.0 0.47 10.2 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Sec63 PF02889.16 PRP78838.1 - 1.9e-133 443.4 0.0 4.3e-69 232.5 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 PRP78838.1 - 3.4e-52 176.7 0.2 1.1e-26 93.6 0.4 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 PRP78838.1 - 5.1e-28 98.2 0.0 3.3e-14 53.2 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP78838.1 - 1.7e-16 60.6 0.0 9.7e-07 29.1 0.0 3.7 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 PRP78838.1 - 1e-07 32.3 0.8 0.00079 19.7 0.1 3.4 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 PRP78838.1 - 0.00012 21.3 0.0 0.36 9.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 PRP78838.1 - 0.00018 21.9 0.4 0.062 13.6 0.3 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PRP78838.1 - 0.0016 18.0 0.0 2.2 7.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 PRP78838.1 - 0.0016 18.1 0.0 0.79 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 PRP78838.1 - 0.0066 16.0 3.7 0.1 12.1 0.1 3.3 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain Helicase_PWI PF18149.1 PRP78838.1 - 0.012 15.8 1.8 0.05 13.8 0.1 2.7 2 0 0 2 2 2 0 N-terminal helicase PWI domain AAA_7 PF12775.7 PRP78838.1 - 0.024 14.1 0.1 9.4 5.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 PRP78838.1 - 0.12 12.1 0.0 4.1 7.1 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein Synaptobrevin PF00957.21 PRP78839.1 - 5.2e-16 58.2 1.4 6.3e-16 57.9 1.1 1.3 1 1 0 1 1 1 1 Synaptobrevin OKR_DC_1 PF01276.20 PRP78839.1 - 0.02 13.7 0.2 0.023 13.4 0.2 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain PDDEXK_1 PF12705.7 PRP78839.1 - 0.04 13.8 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily VanY PF02557.17 PRP78839.1 - 0.077 12.8 0.1 0.098 12.5 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase adh_short PF00106.25 PRP78840.1 - 9.6e-17 61.1 0.0 2.2e-14 53.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 PRP78840.1 - 4.9e-07 29.8 0.0 8.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 PRP78840.1 - 2.2e-05 24.1 0.0 0.0004 20.0 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Sacchrp_dh_NADP PF03435.18 PRP78840.1 - 0.0059 16.9 0.0 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 PRP78840.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 PRP78840.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein G8 PF10162.9 PRP78841.1 - 0.011 15.8 0.1 1.5 8.9 0.2 3.0 2 1 1 3 3 3 0 G8 domain Aminotran_4 PF01063.19 PRP78842.1 - 7.8e-34 117.5 0.0 1e-33 117.1 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV zf-C2H2_jaz PF12171.8 PRP78843.1 - 3.7e-08 33.4 3.1 7e-08 32.6 3.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PRP78843.1 - 0.00025 21.3 0.2 0.00036 20.8 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PRP78843.1 - 0.0014 18.9 1.5 0.0027 18.0 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PRP78843.1 - 0.2 12.6 0.5 0.44 11.5 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3449 PF11931.8 PRP78843.1 - 0.27 11.0 4.8 0.075 12.8 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) DNA_ligase_A_M PF01068.21 PRP78844.1 - 7.4e-63 211.9 0.0 2e-62 210.5 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PRP78844.1 - 2.2e-46 158.3 0.6 6.1e-46 156.9 0.6 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 PRP78844.1 - 1.4e-22 80.1 2.1 3.6e-22 78.8 0.0 2.9 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Red1 PF07964.11 PRP78844.1 - 0.0046 15.3 49.0 0.0081 14.5 49.0 1.4 1 0 0 1 1 1 1 Rec10 / Red1 Pan3_PK PF18101.1 PRP78845.1 - 5.3e-59 198.1 0.3 7.6e-59 197.6 0.3 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 PRP78845.1 - 9.5e-09 35.0 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.24 PRP78845.1 - 0.0014 18.5 3.8 0.0014 18.5 3.8 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP78845.1 - 0.27 11.4 6.0 0.42 10.7 3.5 2.4 2 0 0 2 2 2 0 Zinc finger domain Torus PF16131.5 PRP78845.1 - 0.28 11.9 5.2 0.18 12.5 0.4 2.2 1 1 1 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 PRP78845.1 - 6.3 6.7 13.6 0.15 11.9 2.3 2.7 2 1 0 2 2 2 0 CCCH-type zinc finger Pkinase_Tyr PF07714.17 PRP78846.1 - 3.7e-24 85.4 1.3 1.2e-23 83.7 1.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78846.1 - 2.1e-20 73.2 1.4 5.4e-20 71.9 1.4 1.7 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP78846.1 - 3.8e-08 33.7 5.8 1.4e-07 31.9 5.8 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP78846.1 - 1.1e-06 28.8 26.0 0.0014 19.0 4.3 6.2 1 1 7 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP78846.1 - 5.7e-05 22.9 6.9 0.46 10.7 0.1 6.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 PRP78846.1 - 0.0024 17.6 33.3 0.0048 16.6 2.0 6.0 2 1 4 8 8 8 3 Leucine rich repeat LRR_1 PF00560.33 PRP78846.1 - 0.062 13.9 13.4 16 6.5 0.1 7.2 6 2 0 6 6 6 0 Leucine Rich Repeat Abhydrolase_6 PF12697.7 PRP78847.1 - 3.5e-14 53.9 0.1 4.8e-13 50.2 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP78847.1 - 6.1e-14 52.3 2.3 1.3e-12 47.9 1.5 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP78847.1 - 3.4e-08 33.0 0.0 4.5e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 PRP78847.1 - 0.00038 20.3 0.0 0.0044 16.8 0.0 2.2 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 PRP78847.1 - 0.012 15.8 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 PRP78847.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase IGR PF09597.10 PRP78847.1 - 0.29 11.3 0.8 0.59 10.3 0.8 1.5 1 0 0 1 1 1 0 IGR protein motif Pkinase_Tyr PF07714.17 PRP78848.1 - 9.9e-107 356.0 0.4 4.7e-81 271.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP78848.1 - 3.9e-55 187.0 0.0 1.1e-48 166.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 PRP78848.1 - 2.5e-10 39.9 17.7 0.0056 16.4 0.0 6.3 5 2 1 6 6 6 3 Leucine rich repeat Kinase-like PF14531.6 PRP78848.1 - 1.7e-05 24.3 0.0 5.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PA PF02225.22 PRP78848.1 - 1.7e-05 24.7 0.0 3.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 PA domain LRR_4 PF12799.7 PRP78848.1 - 4.5e-05 23.7 31.2 0.083 13.4 0.2 8.3 8 2 0 8 8 8 3 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 PRP78848.1 - 0.005 15.8 0.0 0.027 13.4 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain LRR_1 PF00560.33 PRP78848.1 - 0.03 14.8 18.6 2e+02 3.2 0.0 10.1 9 1 1 10 10 9 0 Leucine Rich Repeat CYYR1 PF10873.8 PRP78848.1 - 0.037 14.5 1.0 0.072 13.5 0.1 1.9 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 APH PF01636.23 PRP78848.1 - 0.22 11.4 0.2 0.52 10.2 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family B_solenoid_ydck PF18836.1 PRP78848.1 - 0.5 10.3 10.2 7.2 6.7 0.3 3.8 3 0 0 3 3 3 0 Beta solenoid repeat from YDCK CAP_GLY PF01302.25 PRP78849.1 - 1.1e-18 67.0 0.5 1.7e-18 66.4 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain Pkinase_Tyr PF07714.17 PRP78849.1 - 1.2e-14 54.2 0.6 5e-14 52.2 0.4 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78849.1 - 1.8e-06 27.6 0.5 1.8e-06 27.6 0.5 2.3 3 0 0 3 3 3 1 Protein kinase domain Syntaxin_2 PF14523.6 PRP78849.1 - 0.0015 18.8 6.0 0.0035 17.7 6.0 1.5 1 0 0 1 1 1 1 Syntaxin-like protein SPX PF03105.19 PRP78849.1 - 0.35 10.7 8.5 0.03 14.2 3.6 1.6 2 0 0 2 2 2 0 SPX domain ArfGap PF01412.18 PRP78850.1 - 5.7e-45 152.2 5.6 5.3e-44 149.0 0.3 2.8 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf LRR_6 PF13516.6 PRP78852.1 - 1.1e-18 65.7 27.7 1.7e-05 24.5 0.1 10.2 11 0 0 11 11 11 5 Leucine Rich repeat SAM_1 PF00536.30 PRP78852.1 - 2.8e-10 40.5 0.9 9.2e-05 22.8 0.1 3.3 2 1 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP78852.1 - 7.4e-08 32.4 1.6 0.00039 20.5 0.0 3.6 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) LRR_1 PF00560.33 PRP78852.1 - 0.51 11.1 3.8 90 4.2 0.1 5.2 5 1 0 5 5 5 0 Leucine Rich Repeat Kelch_4 PF13418.6 PRP78853.1 - 3.7e-35 119.7 6.1 1.4e-06 28.1 0.0 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP78853.1 - 5.5e-30 102.8 3.2 2.1e-05 24.4 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PRP78853.1 - 2.6e-27 94.2 1.7 1.4e-06 27.8 0.1 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 PRP78853.1 - 3.1e-26 90.7 6.1 2.4e-06 27.6 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 PRP78853.1 - 1.1e-25 89.3 12.0 6.2e-06 26.4 0.1 7.3 7 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP78853.1 - 6.8e-17 60.7 17.6 0.0061 16.5 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Apolipoprotein PF01442.18 PRP78853.1 - 1.5e-05 24.9 21.4 1.5e-05 24.9 21.4 4.4 2 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 PRP78853.1 - 0.00091 19.3 7.6 0.00091 19.3 7.6 6.7 3 2 5 8 8 8 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 PRP78853.1 - 0.0047 17.0 1.8 0.0047 17.0 1.8 6.0 2 1 3 6 6 6 4 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen_mid PF15984.5 PRP78853.1 - 0.066 13.0 0.5 0.2 11.4 0.2 1.8 2 0 0 2 2 2 0 Bacterial collagen, middle region ADH_zinc_N PF00107.26 PRP78856.1 - 1.2e-27 96.4 0.1 2.6e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP78856.1 - 1.9e-17 64.5 0.0 3.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP78856.1 - 1.2e-11 44.4 0.0 1.7e-10 40.8 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 PRP78856.1 - 0.13 12.2 0.1 0.68 9.9 0.0 2.2 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Calsequestrin PF01216.17 PRP78856.1 - 0.19 10.7 0.1 0.3 10.1 0.1 1.3 1 0 0 1 1 1 0 Calsequestrin DUF4446 PF14584.6 PRP78860.1 - 0.082 12.9 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PAN_1 PF00024.26 PRP78861.1 - 5.8e-18 64.6 16.1 0.00019 21.3 1.1 5.3 4 0 0 4 4 4 4 PAN domain PAN_4 PF14295.6 PRP78861.1 - 1.5e-07 31.2 22.1 0.0086 16.0 1.2 5.1 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.12 PRP78861.1 - 0.0062 16.3 19.1 0.059 13.2 2.3 4.3 3 0 0 3 3 3 2 PAN-like domain ZapB PF06005.12 PRP78861.1 - 3 8.4 7.4 5.6 7.5 7.4 1.3 1 0 0 1 1 1 0 Cell division protein ZapB LRR_8 PF13855.6 PRP78862.1 - 1.5e-10 40.7 1.4 1.5e-07 31.1 0.3 3.0 2 1 1 3 3 3 2 Leucine rich repeat ClpS PF02617.17 PRP78862.1 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS LRR_4 PF12799.7 PRP78862.1 - 1.7e-06 28.3 1.4 0.0026 18.1 0.2 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP78862.1 - 1.2e-05 24.9 3.4 0.041 14.0 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat DUF3492 PF11997.8 PRP78863.1 - 0.23 11.1 0.8 0.38 10.4 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) VPS9 PF02204.18 PRP78864.1 - 2.2e-24 85.6 0.0 4e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.6 PRP78864.1 - 2.1e-06 28.1 0.0 3.4e-05 24.3 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP78864.1 - 3.3e-06 27.6 0.0 1.9e-05 25.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP78864.1 - 6e-06 26.2 0.1 0.025 15.1 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP78864.1 - 2.4e-05 24.5 0.0 0.015 15.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP78864.1 - 0.0083 16.5 0.0 3.9 8.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Pkinase_Tyr PF07714.17 PRP78865.1 - 4e-77 259.0 0.0 5.8e-77 258.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78865.1 - 1.4e-52 178.7 0.0 2.2e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_18 PF00704.28 PRP78865.1 - 3.2e-35 122.4 0.4 6.5e-35 121.4 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP78865.1 - 2.3e-16 60.0 78.5 6.8e-08 32.9 20.5 4.3 4 0 0 4 4 4 3 Chitin recognition protein Pkinase_fungal PF17667.1 PRP78865.1 - 0.008 15.0 0.0 0.021 13.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP78865.1 - 0.019 14.3 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 PRP78865.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 14-3-3 PF00244.20 PRP78866.1 - 0.00011 21.8 0.2 0.0023 17.5 0.2 2.2 2 0 0 2 2 2 2 14-3-3 protein LRR_6 PF13516.6 PRP78867.1 - 1.4e-10 40.4 3.0 0.0034 17.3 0.1 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 PRP78867.1 - 6.6e-05 23.2 5.4 0.0052 17.2 0.3 4.5 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) PARP PF00644.20 PRP78867.1 - 0.013 15.1 0.1 0.63 9.6 0.0 2.6 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase catalytic domain LRR_8 PF13855.6 PRP78867.1 - 0.018 14.8 8.0 0.39 10.5 0.4 4.3 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 PRP78867.1 - 0.024 15.1 0.3 7.9 7.5 0.1 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat SH3_1 PF00018.28 PRP78868.1 - 5.2e-27 93.2 0.0 2.6e-13 49.3 0.0 3.3 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 PRP78868.1 - 2.8e-23 81.5 0.0 2e-11 43.5 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 PRP78868.1 - 2e-20 72.2 0.1 2.1e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WW PF00397.26 PRP78868.1 - 1.8e-09 37.5 0.1 5.4e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 WW domain SH3_10 PF17902.1 PRP78868.1 - 0.0014 18.6 0.0 0.1 12.7 0.0 2.8 2 0 0 2 2 2 1 SH3 domain Cas9_b_hairpin PF17893.1 PRP78868.1 - 0.063 13.1 0.3 0.21 11.4 0.3 2.0 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain SH3_3 PF08239.11 PRP78868.1 - 0.4 11.0 2.7 8.5 6.7 0.8 2.8 3 0 0 3 3 3 0 Bacterial SH3 domain KAsynt_C_assoc PF16197.5 PRP78869.1 - 0.13 12.7 0.0 0.61 10.6 0.0 2.2 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Ank_2 PF12796.7 PRP78870.1 - 9.3e-26 90.2 0.8 2.6e-09 37.5 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78870.1 - 1.6e-25 89.1 0.8 2e-13 50.5 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78870.1 - 1.5e-20 71.1 1.3 1.7e-05 24.8 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PRP78870.1 - 7.7e-18 64.3 3.5 3.5e-07 30.4 1.2 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP78870.1 - 2.2e-17 62.6 3.1 1.1e-05 25.6 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Dynamin_N PF00350.23 PRP78870.1 - 3.2e-05 24.1 0.1 0.00026 21.1 0.0 2.2 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.18 PRP78870.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 PRP78870.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sina PF03145.16 PRP78872.1 - 0.0056 16.6 6.2 0.0056 16.6 6.2 2.3 2 1 1 3 3 3 1 Seven in absentia protein family Spc29 PF17082.5 PRP78872.1 - 0.095 12.5 0.9 0.16 11.7 0.9 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 Fibrillarin PF01269.17 PRP78873.1 - 0.026 13.6 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin DUF1148 PF06618.11 PRP78874.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1148) adh_short PF00106.25 PRP78875.1 - 7.3e-40 136.5 0.0 8.7e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP78875.1 - 6.6e-20 71.7 0.0 8.9e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP78875.1 - 4.1e-14 52.9 0.0 5.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP78875.1 - 4.6e-07 29.5 0.0 1.1e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PRP78875.1 - 6.5e-06 25.5 0.1 9.1e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 PRP78875.1 - 9.5e-05 22.9 0.4 0.0002 21.8 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 PRP78875.1 - 0.00076 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 PRP78875.1 - 0.0014 18.2 0.1 0.0031 17.0 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_Gly3P_dh_N PF01210.23 PRP78875.1 - 0.013 15.5 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3Beta_HSD PF01073.19 PRP78875.1 - 0.017 14.2 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PRP78875.1 - 0.033 14.1 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 PRP78875.1 - 0.037 13.1 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 PRP78875.1 - 0.067 13.4 0.0 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Mlh1_C PF16413.5 PRP78876.1 - 6.6e-56 189.7 0.0 3e-55 187.5 0.0 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus AAA_16 PF13191.6 PRP78876.1 - 1.2e-27 97.3 0.0 2.9e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP78876.1 - 2e-26 92.9 0.5 6.4e-26 91.3 0.5 1.9 1 0 0 1 1 1 1 Protein kinase domain HATPase_c PF02518.26 PRP78876.1 - 1.4e-24 86.8 0.5 5.1e-22 78.5 0.2 3.1 3 0 0 3 3 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 PRP78876.1 - 4.7e-23 81.1 0.2 1.2e-22 79.8 0.2 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PRP78876.1 - 1.8e-12 47.3 0.1 5.9e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP78876.1 - 5.4e-09 36.0 0.2 2e-08 34.2 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Kinase-like PF14531.6 PRP78876.1 - 1.4e-05 24.6 1.2 0.00034 20.0 0.2 3.0 3 1 1 4 4 4 1 Kinase-like Response_reg PF00072.24 PRP78876.1 - 0.0001 22.4 0.5 0.0004 20.5 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 PRP78876.1 - 0.00068 20.3 0.0 0.0021 18.7 0.0 1.9 2 0 0 2 2 1 1 GAF domain NARG2_C PF10505.9 PRP78876.1 - 0.036 13.6 1.5 0.098 12.2 1.5 1.7 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus BST2 PF16716.5 PRP78876.1 - 0.037 14.6 1.8 0.086 13.4 0.0 2.6 2 0 0 2 2 1 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 PRP78876.1 - 0.22 11.5 0.9 0.75 9.8 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_22 PF13401.6 PRP78876.1 - 0.25 11.6 1.6 0.78 10.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain Response_reg PF00072.24 PRP78877.1 - 1.3e-12 47.9 0.1 1.5e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF1086 PF06461.11 PRP78877.1 - 0.013 15.4 0.1 0.013 15.3 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Nanovirus_C8 PF05629.11 PRP78878.1 - 0.024 14.7 0.2 0.057 13.5 0.2 1.6 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein G8 PF10162.9 PRP78878.1 - 0.064 13.3 1.7 0.23 11.5 0.4 2.5 2 1 0 2 2 2 0 G8 domain Peptidase_C1 PF00112.23 PRP78879.1 - 3.8e-37 128.5 2.8 8.2e-37 127.4 2.8 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP78879.1 - 5.7e-09 36.3 1.9 7.8e-09 35.8 0.1 2.2 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) HALZ PF02183.18 PRP78879.1 - 5.1e-07 29.8 21.7 0.002 18.3 7.0 4.1 2 1 2 4 4 4 3 Homeobox associated leucine zipper Peptidase_C1_2 PF03051.15 PRP78879.1 - 0.001 17.9 0.0 0.001 17.9 0.0 2.6 3 0 0 3 3 2 1 Peptidase C1-like family DUF3450 PF11932.8 PRP78879.1 - 0.0063 15.9 26.5 0.014 14.8 13.9 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) GAS PF13851.6 PRP78879.1 - 0.0066 15.8 25.4 0.012 15.0 25.4 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding MAD PF05557.13 PRP78879.1 - 0.01 14.2 21.8 0.016 13.6 21.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein JIP_LZII PF16471.5 PRP78879.1 - 0.013 15.6 11.1 0.013 15.6 11.1 2.6 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II ZapB PF06005.12 PRP78879.1 - 0.02 15.3 39.9 32 5.1 16.0 4.0 1 1 1 2 2 2 0 Cell division protein ZapB SHE3 PF17078.5 PRP78879.1 - 0.035 13.8 20.5 0.078 12.7 20.5 1.6 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 PRP78879.1 - 0.045 13.8 32.4 0.39 10.7 32.1 2.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 PRP78879.1 - 0.15 11.8 31.1 0.55 10.0 5.7 4.0 1 1 3 4 4 4 0 Septum formation initiator KASH_CCD PF14662.6 PRP78879.1 - 0.62 9.9 35.1 0.96 9.2 22.7 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH UPF0242 PF06785.11 PRP78879.1 - 0.71 9.9 21.9 1.9 8.6 21.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 PRP78879.1 - 0.73 10.0 29.4 0.91 9.7 9.6 4.5 1 1 4 5 5 5 0 bZIP transcription factor ADIP PF11559.8 PRP78879.1 - 0.82 9.7 31.8 2.9 8.0 15.0 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CCDC92 PF14916.6 PRP78879.1 - 1.5 8.7 7.4 0.089 12.6 1.4 2.2 2 0 0 2 2 1 0 Coiled-coil domain of unknown function DUF874 PF05917.11 PRP78879.1 - 2.4 7.1 23.1 0.071 12.1 15.4 2.0 1 1 1 2 2 2 0 Helicobacter pylori protein of unknown function (DUF874) BLOC1_2 PF10046.9 PRP78879.1 - 3.6 7.9 21.1 0.4 11.0 12.7 2.9 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec20 PF03908.13 PRP78879.1 - 5.8 6.9 8.8 2.3 8.2 3.7 2.9 1 1 1 2 2 2 0 Sec20 bZIP_2 PF07716.15 PRP78879.1 - 7.5 6.7 32.4 1.2 9.2 8.5 4.1 2 1 1 3 3 3 0 Basic region leucine zipper Seryl_tRNA_N PF02403.22 PRP78879.1 - 8.4 6.7 31.6 2.2 8.5 15.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.15 PRP78879.1 - 9.3 5.7 14.6 17 4.8 14.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit MCC-bdg_PDZ PF10506.9 PRP78879.1 - 9.4 6.3 17.4 1.1 9.4 1.3 3.9 2 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Cnn_1N PF07989.11 PRP78879.1 - 9.8 6.4 24.9 13 6.1 12.4 2.9 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF2428 PF10350.9 PRP78880.1 - 5e-65 219.5 0.0 1.2e-64 218.2 0.0 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 PRP78880.1 - 0.0001 22.2 2.3 6.8 7.2 0.1 6.1 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 PRP78880.1 - 0.00021 21.6 0.4 3.7 8.0 0.0 4.4 4 0 0 4 4 4 2 HEAT repeats Proteasom_PSMB PF10508.9 PRP78880.1 - 0.00046 18.8 2.7 0.0011 17.6 2.7 1.6 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Arm_2 PF04826.13 PRP78880.1 - 0.028 13.9 3.1 0.032 13.7 0.4 2.4 3 0 0 3 3 3 0 Armadillo-like zf-MYND PF01753.18 PRP78881.1 - 1.5e-10 40.9 16.7 3.3e-10 39.9 16.7 1.6 1 0 0 1 1 1 1 MYND finger CN_hydrolase PF00795.22 PRP78882.1 - 3.5e-55 187.2 0.0 4.3e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PPR PF01535.20 PRP78883.1 - 0.0073 16.5 0.1 7.7 7.0 0.0 3.2 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 PRP78883.1 - 0.075 13.2 0.1 3 8.1 0.0 2.8 1 1 1 2 2 2 0 PPR repeat family TPR_2 PF07719.17 PRP78884.1 - 5.8e-07 29.1 18.8 4.5e-05 23.3 0.0 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP78884.1 - 2e-06 28.0 17.9 0.00066 19.9 0.0 6.2 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP78884.1 - 1.2e-05 25.2 21.6 0.073 13.3 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP78884.1 - 0.00013 21.7 12.0 0.00032 20.4 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP78884.1 - 0.00024 21.6 16.3 0.037 14.8 0.0 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP78884.1 - 0.00065 19.6 4.5 0.02 14.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP78884.1 - 0.00078 19.9 16.7 0.41 11.2 0.3 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP78884.1 - 0.041 13.6 2.0 0.5 10.1 0.0 3.7 4 0 0 4 4 4 0 TPR repeat TPR_10 PF13374.6 PRP78884.1 - 0.14 12.0 9.0 1.7 8.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat AbiEi_3_N PF17194.4 PRP78884.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain TPR_17 PF13431.6 PRP78884.1 - 0.34 11.4 2.2 1.1e+02 3.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat ZapD PF07072.11 PRP78884.1 - 0.65 9.7 10.3 0.48 10.1 3.4 2.9 2 1 1 3 3 3 0 Cell division protein ANAPC5 PF12862.7 PRP78884.1 - 1.8 8.7 6.4 9.7 6.3 0.4 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 PRP78884.1 - 7 7.5 8.8 18 6.2 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat 2OG-FeII_Oxy PF03171.20 PRP78885.1 - 4.9e-17 62.3 0.0 9.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 PRP78885.1 - 5.5e-14 52.9 0.0 9.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CCDC-167 PF15188.6 PRP78886.1 - 8.8e-09 35.6 4.3 1.1e-08 35.2 4.3 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 Dsl1_C PF11989.8 PRP78886.1 - 0.012 15.4 0.6 0.013 15.2 0.6 1.2 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal FlaC_arch PF05377.11 PRP78886.1 - 0.069 13.6 3.6 0.63 10.5 0.4 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FemAB PF02388.16 PRP78886.1 - 0.071 12.0 2.0 0.083 11.8 2.0 1.0 1 0 0 1 1 1 0 FemAB family DUF1640 PF07798.11 PRP78886.1 - 0.12 12.4 5.2 0.25 11.4 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) LRS4 PF10422.9 PRP78886.1 - 0.21 11.1 4.6 0.24 10.9 4.6 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 FlxA PF14282.6 PRP78886.1 - 0.29 11.1 5.9 0.4 10.7 5.9 1.2 1 0 0 1 1 1 0 FlxA-like protein PEPcase PF00311.17 PRP78888.1 - 8.6e-90 301.9 0.8 1.2e-80 271.7 0.0 2.0 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase Cnl2_NKP2 PF09447.10 PRP78888.1 - 0.13 12.5 0.7 0.83 9.8 0.0 2.6 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Gly_transf_sug PF04488.15 PRP78890.1 - 0.00015 22.3 0.2 0.00037 21.1 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PRP78890.1 - 0.0021 17.5 1.3 0.0031 17.0 1.3 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein RNase_PH PF01138.21 PRP78891.1 - 2e-22 80.1 0.0 3.2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PRP78891.1 - 6.4e-15 54.9 0.1 1.6e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Asn_synthase PF00733.21 PRP78892.1 - 4.6e-94 316.0 0.3 3.5e-56 191.4 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 PRP78892.1 - 1.6e-37 128.2 0.0 2.4e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PRP78892.1 - 3.1e-26 92.2 0.0 5.1e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 PRP78892.1 - 1.2e-07 31.4 0.1 2.2e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 PRP78892.1 - 0.032 13.4 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD synthase HECT PF00632.25 PRP78893.1 - 1.4e-53 182.4 0.1 4.8e-53 180.7 0.0 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.17 PRP78893.1 - 1.9e-16 59.6 22.3 4.5e-13 48.8 9.2 2.6 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_2 PF03107.16 PRP78893.1 - 7.8e-07 29.3 19.9 0.00045 20.5 6.1 3.0 2 0 0 2 2 2 2 C1 domain Peptidase_S64 PF08192.11 PRP78893.1 - 0.026 13.0 6.6 0.056 11.9 6.6 1.5 1 0 0 1 1 1 0 Peptidase family S64 NOA36 PF06524.12 PRP78893.1 - 0.25 10.6 9.6 0.63 9.3 9.6 1.7 1 0 0 1 1 1 0 NOA36 protein VIR_N PF15912.5 PRP78893.1 - 4.6 6.7 15.0 13 5.3 15.0 1.7 1 0 0 1 1 1 0 Virilizer, N-terminal UPF0020 PF01170.18 PRP78894.1 - 1.8e-25 89.8 0.1 1.3e-24 87.0 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 PRP78894.1 - 5e-09 36.7 0.0 6.1e-08 33.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP78894.1 - 1.8e-08 34.4 0.0 3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP78894.1 - 2.8e-06 26.8 0.0 7.2e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 PRP78894.1 - 3.2e-05 24.5 0.0 0.00058 20.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 PRP78894.1 - 0.00063 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.12 PRP78894.1 - 0.00087 20.0 0.0 0.013 16.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 PRP78894.1 - 0.00098 19.1 0.1 0.0074 16.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 PRP78894.1 - 0.0022 17.5 0.0 0.18 11.2 0.1 2.3 1 1 1 2 2 2 1 RRNA methyltransferase AviRa N6_Mtase PF02384.16 PRP78894.1 - 0.0048 16.2 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_33 PF10017.9 PRP78894.1 - 0.011 14.8 0.1 0.059 12.5 0.0 1.9 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent MTS PF05175.14 PRP78894.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 PRP78894.1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1660 PF07874.11 PRP78894.1 - 0.1 13.1 0.3 0.71 10.4 0.1 2.4 2 1 0 2 2 2 0 Prophage protein (DUF1660) Methyltransf_15 PF09445.10 PRP78894.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase C2 PF00168.30 PRP78896.1 - 3.7e-30 104.3 1.1 1.8e-15 57.1 0.4 2.4 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 PRP78896.1 - 8.9e-23 81.1 0.0 2.4e-12 47.0 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 PRP78896.1 - 2.7e-11 43.9 0.5 2.7e-11 43.9 0.5 2.4 2 1 1 3 3 3 1 PH domain Tetraspanin PF00335.20 PRP78897.1 - 0.018 14.8 3.9 0.025 14.3 3.9 1.3 1 1 0 1 1 1 0 Tetraspanin family ABC2_membrane_2 PF12679.7 PRP78897.1 - 0.12 11.6 1.0 0.15 11.3 1.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein AC_N PF16214.5 PRP78897.1 - 0.89 8.6 2.4 1.2 8.2 1.9 1.4 1 1 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region DUF2157 PF09925.9 PRP78897.1 - 1.2 8.9 5.4 2.4 7.9 0.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Pkinase PF00069.25 PRP78898.1 - 2.1e-06 27.3 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP78898.1 - 0.00034 19.5 0.0 0.00049 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase HSDR_N PF04313.14 PRP78898.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) F-box PF00646.33 PRP78902.1 - 2.1e-07 30.6 2.2 4e-07 29.7 0.7 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP78902.1 - 5.8e-07 29.3 0.6 1.4e-06 28.0 0.6 1.7 1 0 0 1 1 1 1 F-box-like LNS2 PF08235.13 PRP78903.1 - 2.2e-12 46.9 0.0 4.6e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Retrotran_gag_2 PF14223.6 PRP78903.1 - 0.024 14.3 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Acid_PPase PF12689.7 PRP78904.1 - 7.5e-07 29.1 0.4 9e-06 25.6 0.3 2.3 1 1 1 2 2 2 1 Acid Phosphatase PGP_phosphatase PF09419.10 PRP78904.1 - 0.0047 16.6 0.1 0.023 14.3 0.0 1.9 1 1 1 2 2 2 1 Mitochondrial PGP phosphatase HAD_2 PF13419.6 PRP78904.1 - 0.0074 16.4 0.4 0.036 14.1 0.3 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF3157 PF11355.8 PRP78904.1 - 0.043 13.4 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Transposase_28 PF04195.12 PRP78904.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Putative gypsy type transposon Hydrolase PF00702.26 PRP78904.1 - 0.12 12.7 0.0 0.51 10.6 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Lipase_3 PF01764.25 PRP78905.1 - 2.1e-05 24.4 0.0 7.5e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 PRP78905.1 - 0.00012 22.0 0.0 0.00036 20.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) AIG1 PF04548.16 PRP78906.1 - 3.9e-09 36.1 0.1 6.1e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PRP78906.1 - 0.00013 22.0 0.1 0.00044 20.3 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP78906.1 - 0.00069 19.6 1.9 0.00099 19.0 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 PRP78906.1 - 0.0019 17.9 0.1 0.0065 16.2 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 PRP78906.1 - 0.0038 17.3 0.6 2.5 8.1 0.2 2.4 1 1 1 2 2 2 2 Dynamin family DUF4097 PF13349.6 PRP78906.1 - 0.0068 15.8 5.3 0.019 14.3 5.0 1.9 1 1 0 1 1 1 1 Putative adhesin AAA_16 PF13191.6 PRP78906.1 - 0.01 16.2 0.1 0.029 14.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 PRP78906.1 - 0.019 14.3 0.4 0.12 11.6 0.4 2.1 1 1 0 1 1 1 0 Septin Roc PF08477.13 PRP78906.1 - 0.021 15.1 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF2807 PF10988.8 PRP78906.1 - 0.11 12.3 4.1 2.5 7.9 3.7 3.1 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Cadherin_4 PF17803.1 PRP78906.1 - 0.37 11.4 2.0 1.9 9.2 0.3 3.2 3 1 0 3 3 2 0 Bacterial cadherin-like domain DHHC PF01529.20 PRP78907.1 - 6.7e-05 23.0 2.9 9.2e-05 22.6 2.9 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase MCM PF00493.23 PRP78909.1 - 0.036 13.2 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Pkinase PF00069.25 PRP78910.1 - 1.8e-65 220.9 0.0 3e-65 220.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78910.1 - 1.8e-46 158.5 0.0 3e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP78910.1 - 3.1e-05 22.9 0.0 6.8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP78910.1 - 0.0037 16.6 0.0 0.012 14.9 0.0 1.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PRP78910.1 - 0.0055 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP78910.1 - 0.0097 15.3 0.1 0.031 13.6 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_10 PF15411.6 PRP78910.1 - 0.051 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain NTP_transf_7 PF07984.12 PRP78911.1 - 1.1e-33 116.8 2.9 2.8e-33 115.5 2.9 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase NUDIX_2 PF13869.6 PRP78912.1 - 4.7e-67 225.2 0.0 7.5e-67 224.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase ATP-synt_F PF01990.17 PRP78912.1 - 0.04 14.2 2.1 0.13 12.6 2.1 1.9 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit SM-ATX PF14438.6 PRP78912.1 - 0.17 12.0 0.1 16 5.7 0.0 2.3 1 1 1 2 2 2 0 Ataxin 2 SM domain Miga PF10265.9 PRP78912.1 - 0.35 9.8 3.4 0.44 9.5 3.4 1.1 1 0 0 1 1 1 0 Mitoguardin PI3K_1B_p101 PF10486.9 PRP78912.1 - 1.1 6.9 3.9 1.3 6.7 3.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Acyltransferase PF01553.21 PRP78913.1 - 1.5e-25 89.4 0.1 2.1e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Acyltransferase CH PF00307.31 PRP78914.1 - 2.1e-34 118.0 0.3 5.5e-17 61.9 0.1 3.4 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP78914.1 - 0.0089 15.8 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain Abhydrolase_2 PF02230.16 PRP78915.1 - 6.3e-23 81.7 0.1 2.5e-22 79.8 0.0 1.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 PRP78915.1 - 2e-05 24.4 0.0 3.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.22 PRP78915.1 - 0.00097 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Cutinase DLH PF01738.18 PRP78915.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 PRP78915.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Armet PF10208.9 PRP78915.1 - 0.0029 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Abhydrolase_1 PF00561.20 PRP78915.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 PRP78915.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 PRP78915.1 - 0.059 14.0 0.0 0.085 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.11 PRP78915.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Fz PF01392.22 PRP78916.1 - 0.001 19.6 5.8 0.001 19.6 5.8 1.8 1 1 0 2 2 2 1 Fz domain Allene_ox_cyc PF06351.11 PRP78916.1 - 0.13 12.0 0.3 0.2 11.4 0.3 1.2 1 0 0 1 1 1 0 Allene oxide cyclase TYA PF01021.19 PRP78917.1 - 0.11 12.8 0.9 0.29 11.5 0.2 1.9 2 0 0 2 2 2 0 TYA transposon protein SH2 PF00017.24 PRP78918.1 - 5.5e-13 48.8 2.1 8.6e-13 48.2 0.1 2.3 2 0 0 2 2 2 1 SH2 domain Pkinase_Tyr PF07714.17 PRP78918.1 - 2e-05 24.0 0.0 0.011 15.1 0.0 2.6 1 1 0 2 2 2 2 Protein tyrosine kinase TFIIA_gamma_N PF02268.16 PRP78918.1 - 6.1e-05 22.9 0.2 6.1e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit, helical domain V-ATPase_G PF03179.15 PRP78918.1 - 0.0073 16.8 17.6 0.0073 16.8 17.6 2.2 1 1 1 2 2 2 1 Vacuolar (H+)-ATPase G subunit TFIIA_gamma_C PF02751.14 PRP78918.1 - 0.02 15.0 0.1 0.048 13.8 0.1 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit Spc7 PF08317.11 PRP78918.1 - 0.34 9.7 32.1 0.62 8.9 32.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 PRP78918.1 - 0.72 10.4 34.7 3.3 8.2 22.8 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Pkinase PF00069.25 PRP78919.1 - 1e-69 234.9 0.1 1.9e-69 234.0 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78919.1 - 5e-37 127.6 0.1 1.2e-36 126.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PAS PF00989.25 PRP78919.1 - 1.5e-20 73.3 0.0 4.4e-08 33.1 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 PRP78919.1 - 2.1e-19 69.7 0.0 6.1e-07 29.6 0.0 4.5 4 0 0 4 4 4 3 PAS domain Kinase-like PF14531.6 PRP78919.1 - 9.1e-10 38.3 0.0 1.3e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAS_4 PF08448.10 PRP78919.1 - 4e-06 27.0 0.0 0.73 10.1 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_3 PF08447.12 PRP78919.1 - 5.9e-05 23.3 0.0 2.3 8.6 0.0 4.2 4 0 0 4 4 4 2 PAS fold Pkinase_fungal PF17667.1 PRP78919.1 - 0.00037 19.4 0.1 0.00059 18.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP78919.1 - 0.0029 16.6 0.2 0.0046 15.9 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Big_9 PF17963.1 PRP78919.1 - 0.0059 17.3 11.8 0.26 12.1 9.0 3.0 2 1 0 2 2 1 1 Bacterial Ig domain APH PF01636.23 PRP78919.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS_8 PF13188.7 PRP78919.1 - 0.053 13.6 0.0 4.3 7.5 0.0 3.0 3 0 0 3 3 3 0 PAS domain REJ PF02010.15 PRP78921.1 - 9.2e-19 67.5 20.8 1.7e-17 63.3 9.6 3.8 3 0 0 3 3 3 2 REJ domain PKD_2 PF16407.5 PRP78921.1 - 0.0037 17.5 0.2 0.054 13.7 0.0 2.7 2 0 0 2 2 2 1 PKD-like family DUF4690 PF15756.5 PRP78921.1 - 0.0046 17.5 0.3 0.026 15.1 0.3 2.3 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 PRP78921.1 - 0.062 13.4 8.8 0.064 13.4 0.4 3.0 2 0 0 2 2 2 0 Podoplanin MtrF PF09472.10 PRP78921.1 - 3.5 7.1 8.6 0.69 9.3 4.7 1.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Glyco_hydro_3_C PF01915.22 PRP78922.1 - 3.2e-45 154.6 0.0 4.7e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PRP78922.1 - 2.1e-43 148.9 0.0 5.7e-43 147.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 PRP78922.1 - 1.7e-15 57.1 0.0 3.6e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 PRP78922.1 - 8.3e-15 54.7 0.0 2.2e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1279 PF06916.13 PRP78923.1 - 1.5e-16 60.7 0.3 1.9e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) MatE PF01554.18 PRP78923.1 - 0.0048 16.6 3.9 0.17 11.5 0.0 2.0 1 1 1 2 2 2 2 MatE NrsF PF06532.11 PRP78923.1 - 0.064 13.0 1.5 0.077 12.7 1.5 1.1 1 0 0 1 1 1 0 Negative regulator of sigma F DUF418 PF04235.12 PRP78923.1 - 0.15 12.0 2.3 0.39 10.6 1.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF418) V-SNARE_C PF12352.8 PRP78924.1 - 5.2e-08 33.0 13.3 0.0016 18.6 1.2 3.3 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 PRP78924.1 - 0.0012 18.8 5.3 0.27 11.3 0.2 2.7 2 0 0 2 2 2 2 SNARE domain DUF5089 PF17002.5 PRP78924.1 - 0.01 15.7 0.8 0.01 15.7 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5089) bPH_3 PF14470.6 PRP78924.1 - 0.012 15.9 0.1 3.9 7.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial PH domain DUF16 PF01519.16 PRP78924.1 - 0.14 12.6 7.1 0.13 12.8 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 PRP78924.1 - 0.27 11.7 8.1 0.9 10.0 1.3 3.8 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 PRP78924.1 - 0.91 9.5 4.9 1.9 8.5 0.9 2.6 2 0 0 2 2 2 0 Laminin Domain II Copine PF07002.16 PRP78925.1 - 4.6e-58 196.2 0.0 6.7e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 PRP78925.1 - 2.3e-09 37.7 0.0 5.8e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 vWA found in TerF C terminus MFS_1 PF07690.16 PRP78926.1 - 1.6e-42 145.7 44.2 4.2e-41 141.0 39.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 PRP78926.1 - 1.6e-17 63.2 12.8 1.8e-09 36.6 1.8 2.8 2 1 1 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 PRP78926.1 - 4.1e-15 55.6 19.0 2.4e-13 49.8 3.2 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Acetyltransf_1 PF00583.25 PRP78927.1 - 6.8e-11 42.4 0.2 9.3e-11 42.0 0.2 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP78927.1 - 1.5e-08 34.6 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP78927.1 - 2.9e-08 34.0 0.0 4.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP78927.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 PRP78927.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 PRP78927.1 - 0.027 15.1 0.0 0.036 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RNase_PH PF01138.21 PRP78928.1 - 8.4e-23 81.3 0.0 1.4e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PRP78928.1 - 3.9e-15 55.6 0.1 7.5e-15 54.7 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NIF PF03031.18 PRP78929.1 - 3e-15 56.3 0.0 4.4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Biotin_lipoyl PF00364.22 PRP78929.1 - 0.072 12.9 0.0 0.3 10.9 0.0 2.0 2 1 0 2 2 2 0 Biotin-requiring enzyme NQRA PF05896.11 PRP78929.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RRN9 PF10680.9 PRP78930.1 - 0.11 12.8 0.3 0.11 12.8 0.3 3.9 3 1 0 3 3 3 0 RNA polymerase I specific transcription initiation factor DUF4407 PF14362.6 PRP78930.1 - 8.1 5.7 47.5 2.9 7.2 22.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) V-SNARE_C PF12352.8 PRP78932.1 - 1.1e-09 38.4 3.0 1.4e-08 34.9 2.9 2.4 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 PRP78932.1 - 0.004 17.5 2.3 0.0078 16.6 0.7 2.4 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 PRP78932.1 - 0.0064 16.4 1.2 0.027 14.4 0.0 2.4 1 1 2 3 3 3 1 Sec20 DUF3334 PF11813.8 PRP78932.1 - 0.033 13.9 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) RRF PF01765.19 PRP78932.1 - 0.038 14.0 1.3 0.15 12.0 1.3 2.0 1 1 0 1 1 1 0 Ribosome recycling factor Orf78 PF06024.12 PRP78932.1 - 0.042 14.1 1.8 0.21 11.9 1.7 2.2 1 1 0 1 1 1 0 Orf78 (ac78) PhoU PF01895.19 PRP78932.1 - 0.045 14.2 0.3 0.12 12.8 0.3 1.8 1 1 0 1 1 1 0 PhoU domain YqjK PF13997.6 PRP78932.1 - 0.045 14.0 1.5 0.31 11.3 0.3 2.6 3 0 0 3 3 3 0 YqjK-like protein DUF1664 PF07889.12 PRP78932.1 - 0.082 12.9 5.2 0.2 11.7 1.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3552 PF12072.8 PRP78932.1 - 0.088 12.2 5.5 0.16 11.4 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) YscO-like PF16789.5 PRP78932.1 - 0.18 11.8 5.0 0.25 11.4 3.4 1.9 1 1 1 2 2 2 0 YscO-like protein DUF5345 PF17280.2 PRP78932.1 - 3.4 7.7 6.6 0.39 10.7 2.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Ras PF00071.22 PRP78933.1 - 1.3e-25 89.9 0.0 1.9e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP78933.1 - 1.6e-11 44.5 0.0 4.6e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PRP78933.1 - 0.00048 20.1 0.2 0.0042 17.0 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 PRP78933.1 - 0.0019 17.6 0.5 0.012 14.9 0.0 2.3 3 0 0 3 3 3 1 Septin MMR_HSR1 PF01926.23 PRP78933.1 - 0.0022 18.1 0.3 0.0053 16.8 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 PRP78933.1 - 0.0068 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 PRP78933.1 - 0.013 15.0 0.0 0.036 13.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 PRP78933.1 - 0.076 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 PRP78933.1 - 0.091 12.5 0.1 0.18 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain TPR_2 PF07719.17 PRP78934.1 - 3.2e-05 23.7 0.0 0.052 13.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP78934.1 - 0.0013 18.4 0.0 0.9 9.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat FTCD_C PF04961.12 PRP78934.1 - 0.18 11.6 0.9 0.41 10.4 0.9 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Relaxase PF03432.14 PRP78934.1 - 0.93 9.0 7.3 0.2 11.2 0.3 2.1 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain Ge1_WD40 PF16529.5 PRP78935.1 - 5.2e-08 32.2 0.1 5.1e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 PRP78935.1 - 0.0067 17.3 1.5 0.92 10.5 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat RRN3 PF05327.11 PRP78935.1 - 0.34 9.4 4.5 0.54 8.7 4.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 T3SS_basalb_I PF17001.5 PRP78935.1 - 1.9 9.1 4.5 4.6 7.9 2.7 2.4 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Stn1 PF10451.9 PRP78935.1 - 5.6 5.8 7.9 0.7 8.8 0.1 2.4 2 0 0 2 2 2 0 Telomere regulation protein Stn1 Guanylate_cyc PF00211.20 PRP78937.1 - 2.7e-54 183.6 0.0 1.5e-29 102.9 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF4874 PF16173.5 PRP78939.1 - 1.5e-18 67.0 0.2 1.7e-08 34.3 0.0 3.4 3 1 0 3 3 3 2 Domain of unknown function (DUF4874) DUF4832 PF16116.5 PRP78939.1 - 2.6e-11 43.8 1.3 1.7e-06 28.1 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4832) tRNA-synt_2 PF00152.20 PRP78941.1 - 1.3e-81 274.1 0.2 1.9e-81 273.6 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PRP78941.1 - 1.3e-11 44.3 0.0 3e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PRP78941.1 - 1.1e-06 28.3 0.0 0.01 15.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TMEM215 PF15746.5 PRP78941.1 - 0.019 14.4 0.7 0.036 13.5 0.7 1.3 1 0 0 1 1 1 0 TMEM215 family TAF4 PF05236.14 PRP78941.1 - 0.13 11.9 6.7 0.22 11.2 6.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DHHW PF14286.6 PRP78941.1 - 1.2 8.4 4.8 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 DHHW protein RNA_pol_Rpc4 PF05132.14 PRP78941.1 - 2.9 8.3 7.1 7.2 7.0 7.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 PRP78941.1 - 4.4 6.1 12.0 7.9 5.3 12.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Linker_histone PF00538.19 PRP78942.1 - 1.8e-10 41.0 0.2 6.2e-10 39.3 0.0 2.0 2 1 0 2 2 2 1 linker histone H1 and H5 family Recombinase PF07508.13 PRP78942.1 - 0.28 11.6 5.1 0.24 11.8 2.9 2.0 2 2 0 2 2 2 0 Recombinase PDEase_I_N PF08499.12 PRP78942.1 - 6.5 6.7 6.3 4.8 7.1 0.1 3.0 4 0 0 4 4 4 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Syntaxin PF00804.25 PRP78944.1 - 7.9e-27 94.2 14.3 7.9e-27 94.2 14.3 2.7 3 1 0 3 3 3 1 Syntaxin SNARE PF05739.19 PRP78944.1 - 3.8e-09 36.4 0.2 9e-09 35.2 0.2 1.6 1 0 0 1 1 1 1 SNARE domain SH3_1 PF00018.28 PRP78945.1 - 9.2e-10 38.0 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP78945.1 - 7.7e-08 32.1 0.1 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP78945.1 - 0.0002 21.0 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Laminin_G_3 PF13385.6 PRP78946.1 - 1.4e-35 122.7 11.5 5.5e-20 72.0 0.1 4.3 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily Asn_synthase PF00733.21 PRP78946.1 - 6.2e-18 65.6 0.0 8.7e-08 32.2 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase GATase_6 PF13522.6 PRP78946.1 - 3.8e-05 23.9 0.0 9.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 PRP78946.1 - 6.4e-05 22.9 0.0 0.0004 20.3 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase domain Toxin_R_bind_N PF07953.12 PRP78946.1 - 0.0016 18.2 0.8 3 7.5 1.0 2.9 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding DUF4982 PF16355.5 PRP78946.1 - 0.042 13.8 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) Carb_bind PF10645.9 PRP78946.1 - 4.5 7.6 28.5 0.82 9.9 5.7 3.9 3 0 0 3 3 3 0 Carbohydrate binding Fe-S_biosyn PF01521.20 PRP78947.1 - 7.6e-19 67.9 0.0 8.8e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Pkinase PF00069.25 PRP78948.1 - 3e-77 259.6 0.0 3.6e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP78948.1 - 3.8e-36 124.7 0.0 4.9e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PRP78948.1 - 2e-06 28.4 3.6 5.8e-06 26.9 3.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 PRP78948.1 - 6.3e-05 22.1 0.2 8.8e-05 21.6 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PRP78948.1 - 9.9e-05 21.8 0.3 0.00093 18.6 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PRP78948.1 - 0.002 17.0 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 PRP78948.1 - 0.0021 17.7 0.3 0.23 11.0 0.2 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PRP78948.1 - 0.0093 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Syntaxin PF00804.25 PRP78949.1 - 9.2e-49 165.8 18.0 9.2e-49 165.8 18.0 1.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 PRP78949.1 - 1.1e-14 54.1 1.3 1.1e-14 54.1 1.3 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 PRP78949.1 - 5.5e-08 33.1 6.5 5.5e-08 33.1 6.5 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Arc_PepC_II PF06847.11 PRP78949.1 - 0.75 10.4 3.0 1.5 9.4 0.6 2.6 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Herpes_US9 PF06072.11 PRP78949.1 - 2.2 8.2 4.5 0.47 10.4 0.6 1.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 ETRAMP PF09716.10 PRP78949.1 - 4.8 7.3 11.2 0.051 13.6 1.3 2.5 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PAH PF02671.21 PRP78949.1 - 8.5 6.6 6.5 19 5.5 6.5 1.7 1 1 0 1 1 1 0 Paired amphipathic helix repeat G-patch PF01585.23 PRP78950.1 - 1.9e-15 56.4 0.3 3.6e-15 55.6 0.3 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 PRP78950.1 - 2.7e-07 30.3 0.1 5.8e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dynein_light PF01221.18 PRP78950.1 - 0.022 15.0 0.0 0.067 13.5 0.0 1.8 1 0 0 1 1 1 0 Dynein light chain type 1 G-patch_2 PF12656.7 PRP78950.1 - 0.025 14.6 1.6 0.032 14.3 0.1 2.0 2 0 0 2 2 2 0 G-patch domain Med3 PF11593.8 PRP78950.1 - 0.26 10.4 10.0 0.41 9.8 10.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3573 PF12097.8 PRP78951.1 - 2.1 7.1 3.3 3.8 6.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF5486 PF17588.2 PRP78951.1 - 5.8 6.9 7.8 0.91 9.5 0.7 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5486) DEAD PF00270.29 PRP78953.1 - 2.2e-52 177.4 0.0 6.9e-52 175.8 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP78953.1 - 4.3e-28 97.9 0.0 1.4e-27 96.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP78953.1 - 1.3e-06 28.6 0.0 1.3e-06 28.6 0.0 3.8 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit IQ PF00612.27 PRP78953.1 - 2.6e-06 26.7 7.1 0.00014 21.3 0.3 2.9 2 0 0 2 2 2 2 IQ calmodulin-binding motif CW_binding_2 PF04122.12 PRP78953.1 - 0.058 14.1 1.9 0.18 12.5 1.3 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 ThiI PF02568.14 PRP78953.1 - 0.062 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Terminase_6 PF03237.15 PRP78953.1 - 2.8 7.5 0.0 2.8 7.5 0.0 3.8 4 1 0 4 4 4 0 Terminase-like family PAP_central PF04928.17 PRP78954.1 - 1.6e-109 364.7 0.0 2.1e-109 364.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 PRP78954.1 - 1.6e-31 109.3 0.0 8.1e-31 106.9 0.0 2.1 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 PRP78954.1 - 2.6e-09 37.2 0.0 7.9e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 PRP78954.1 - 0.0053 16.5 0.4 0.023 14.5 0.1 2.2 2 1 0 2 2 2 1 Nrap protein PAP/OAS-like domain DNA_pol_B_palm PF14792.6 PRP78954.1 - 0.0058 16.8 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm Pribosyltran_N PF13793.6 PRP78955.1 - 3e-34 117.4 0.0 2.8e-28 98.2 0.0 3.2 3 0 0 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 PRP78955.1 - 5.3e-23 82.0 4.8 9.6e-21 74.6 2.4 2.9 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Dicty_CAR PF05462.11 PRP78955.1 - 4.4e-16 58.9 13.2 8e-16 58.0 13.2 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 PRP78955.1 - 1.7e-08 34.0 13.8 5e-08 32.5 13.8 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 PRP78955.1 - 9.9e-07 28.1 19.8 0.0002 20.5 6.4 2.2 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region GPR_Gpa2_C PF11970.8 PRP78955.1 - 0.0027 17.8 0.1 0.0076 16.3 0.1 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Pribosyltran PF00156.27 PRP78955.1 - 0.003 17.1 1.9 0.014 14.9 1.9 2.2 2 1 0 2 2 2 1 Phosphoribosyl transferase domain 7tm_1 PF00001.21 PRP78955.1 - 4 6.7 12.3 9.1 5.5 12.3 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ribosomal_L28e PF01778.17 PRP78957.1 - 1.3e-35 122.6 0.3 1.3e-35 122.6 0.3 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 PRP78957.1 - 6e-16 58.9 21.6 6e-16 58.9 21.6 1.8 2 0 0 2 2 2 1 Mak16 protein C-terminal region Nop14 PF04147.12 PRP78957.1 - 0.031 12.5 19.5 0.04 12.1 19.5 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 PRP78957.1 - 0.049 13.6 8.5 0.064 13.2 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PP_M1 PF03012.14 PRP78957.1 - 0.32 10.5 12.4 0.16 11.5 9.2 1.9 1 1 1 2 2 2 0 Phosphoprotein Hairy_orange PF07527.13 PRP78958.1 - 0.0017 18.5 0.1 0.01 16.0 0.0 2.3 2 0 0 2 2 2 1 Hairy Orange Phage_Gp111 PF07410.11 PRP78958.1 - 0.19 12.2 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein Zn_clus PF00172.18 PRP78958.1 - 4 7.6 10.7 1.2 9.3 6.9 2.2 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 PRP78959.1 - 1.4e-46 158.6 0.3 2.5e-46 157.8 0.3 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 PRP78959.1 - 4.9e-08 32.5 2.0 0.071 13.2 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP78959.1 - 9.2e-08 32.5 2.4 1.4e-05 25.5 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP78959.1 - 0.00012 22.6 0.2 0.18 12.7 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP78959.1 - 0.00041 20.9 2.5 0.068 13.8 0.1 2.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP78959.1 - 0.0013 18.8 4.0 0.58 10.5 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat YfiO PF13525.6 PRP78959.1 - 0.0013 18.5 3.1 0.0019 17.9 3.1 1.3 1 0 0 1 1 1 1 Outer membrane lipoprotein TPR_11 PF13414.6 PRP78959.1 - 0.0016 18.1 0.0 0.0016 18.1 0.0 2.2 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 PRP78959.1 - 0.0018 18.0 3.4 1.6 8.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP78959.1 - 0.082 13.0 3.4 4.9 7.3 0.0 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 PRP78959.1 - 0.2 12.4 2.8 41 5.1 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP78959.1 - 0.22 11.8 2.3 0.54 10.5 0.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PRP78959.1 - 0.25 11.6 1.6 1.4 9.2 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2572 PF10833.8 PRP78959.1 - 0.43 10.3 2.9 0.48 10.2 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) CENP-H PF05837.12 PRP78959.1 - 5 7.6 6.4 0.8 10.1 0.2 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) MCPVI PF02993.14 PRP78960.1 - 4.3 7.1 8.8 16 5.2 8.9 2.0 1 1 0 1 1 1 0 Minor capsid protein VI TMEM154 PF15102.6 PRP78961.1 - 0.00069 19.5 0.3 0.0014 18.6 0.3 1.4 1 0 0 1 1 1 1 TMEM154 protein family SAM_3 PF18016.1 PRP78961.1 - 0.013 15.3 1.2 0.47 10.3 0.0 4.2 6 2 2 8 8 8 0 SAM domain (Sterile alpha motif) DIL PF01843.19 PRP78961.1 - 0.087 13.1 0.5 28 5.0 0.0 4.2 4 0 0 4 4 4 0 DIL domain DUF4448 PF14610.6 PRP78961.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Vpu PF00558.19 PRP78961.1 - 0.16 11.8 0.1 0.43 10.4 0.1 1.8 1 0 0 1 1 1 0 Vpu protein PMP1_2 PF08114.11 PRP78961.1 - 0.45 10.3 1.5 0.96 9.2 1.5 1.5 1 0 0 1 1 1 0 ATPase proteolipid family IF4E PF01652.18 PRP78962.1 - 1.9e-56 190.3 1.7 2.3e-56 190.0 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PNRC PF15365.6 PRP78964.1 - 7.3e-05 22.5 4.3 7.3e-05 22.5 4.3 2.7 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif CYYR1 PF10873.8 PRP78964.1 - 9 6.7 6.6 30 5.0 0.9 2.2 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Pam16 PF03656.13 PRP78965.1 - 0.048 13.7 0.0 0.17 11.9 0.0 2.0 1 0 0 1 1 1 0 Pam16 MinE PF03776.14 PRP78965.1 - 0.68 10.0 4.2 3.8 7.6 0.4 2.9 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE TGase_elicitor PF16683.5 PRP78966.1 - 8.1e-27 93.9 6.0 1.1e-20 73.8 1.5 3.1 2 1 0 2 2 2 2 Transglutaminase elicitor CUB PF00431.20 PRP78966.1 - 4.3e-08 33.5 0.1 1.4e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 CUB domain IQ PF00612.27 PRP78967.1 - 0.0025 17.5 0.1 0.011 15.4 0.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF3484 PF11983.8 PRP78967.1 - 1.3 10.2 9.2 7.3 7.8 0.0 4.0 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Methyltransf_16 PF10294.9 PRP78968.1 - 8.9e-17 61.4 0.1 1.1e-15 57.8 0.1 2.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 PRP78968.1 - 0.00096 19.0 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP78968.1 - 0.046 13.1 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 PRP78968.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 PRP78968.1 - 0.29 11.8 1.0 15 6.3 0.6 3.0 2 1 0 2 2 2 0 Methyltransferase domain PI3_PI4_kinase PF00454.27 PRP78969.1 - 4.2e-27 95.5 5.2 2e-23 83.5 0.2 3.1 3 1 1 4 4 4 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PRP78969.1 - 0.00052 19.5 0.3 0.0018 17.7 0.3 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ribosomal_L17 PF01196.19 PRP78969.1 - 0.16 12.9 1.2 0.54 11.2 1.2 1.9 1 0 0 1 1 1 0 Ribosomal protein L17 Prefoldin_2 PF01920.20 PRP78969.1 - 0.71 9.9 15.4 2.3 8.2 0.4 3.2 2 0 0 2 2 2 0 Prefoldin subunit MutS_V PF00488.21 PRP78970.1 - 4.3e-68 229.1 0.8 7.5e-68 228.3 0.8 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PRP78970.1 - 3.3e-29 102.5 2.5 6.7e-29 101.5 0.5 2.3 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 PRP78970.1 - 2.4e-16 60.0 0.1 5.6e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 PRP78970.1 - 2.9e-08 34.1 0.0 8.1e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 MutS domain II Nramp PF01566.18 PRP78971.1 - 4e-21 75.4 1.6 4.8e-21 75.1 1.6 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF4657 PF15552.6 PRP78971.1 - 0.03 13.9 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) RSN1_7TM PF02714.15 PRP78972.1 - 1.3e-62 211.6 23.0 1.7e-62 211.3 23.0 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate GP41 PF00517.17 PRP78972.1 - 0.58 10.0 2.9 0.53 10.2 1.2 1.8 2 0 0 2 2 2 0 Retroviral envelope protein Pkinase_Tyr PF07714.17 PRP78973.1 - 6.1e-56 189.6 0.1 1.2e-55 188.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP78973.1 - 3.7e-51 174.0 0.0 6.8e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PBP_like_2 PF12849.7 PRP78973.1 - 0.00014 21.7 0.0 0.0004 20.1 0.0 1.7 2 0 0 2 2 2 1 PBP superfamily domain APH PF01636.23 PRP78973.1 - 0.058 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP78973.1 - 0.13 11.2 0.4 14 4.5 0.1 2.2 2 0 0 2 2 2 0 Haspin like kinase domain HEPN PF05168.14 PRP78974.1 - 9.1e-11 41.9 0.5 9.1e-11 41.9 0.5 2.8 3 0 0 3 3 3 1 HEPN domain HATPase_c_3 PF13589.6 PRP78974.1 - 0.0027 17.5 0.2 0.36 10.7 0.0 3.0 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_2 PF12796.7 PRP78975.1 - 4.5e-17 62.4 0.0 1.3e-07 32.1 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP78975.1 - 2.6e-13 50.2 0.7 3.4e-05 24.3 0.0 4.2 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP78975.1 - 1.5e-11 43.4 0.0 0.074 13.6 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 PRP78975.1 - 2.1e-09 37.4 0.0 0.025 15.0 0.0 4.3 2 2 1 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 PRP78975.1 - 1.9e-08 34.4 0.3 0.048 14.0 0.0 5.0 1 1 4 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP78975.1 - 0.027 14.4 0.1 0.074 13.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like HrcA PF01628.21 PRP78976.1 - 0.048 13.6 0.0 0.053 13.4 0.0 1.0 1 0 0 1 1 1 0 HrcA protein C terminal domain RsgI_N PF12791.7 PRP78976.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor N-terminus E1-E2_ATPase PF00122.20 PRP78977.1 - 6.6e-43 146.3 3.1 6.6e-43 146.3 3.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PRP78977.1 - 2.6e-37 128.3 1.1 2.6e-37 128.3 1.1 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PRP78977.1 - 1e-21 78.2 0.8 2.7e-20 73.6 0.8 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP78977.1 - 2.1e-15 56.5 0.0 1.1e-14 54.3 0.0 2.3 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PRP78977.1 - 2.2e-14 52.9 0.0 5.4e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PRP78977.1 - 0.0077 16.0 0.2 0.052 13.3 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TPT PF03151.16 PRP78978.1 - 1.5e-15 57.3 23.5 2e-15 56.9 23.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PRP78978.1 - 0.01 15.1 20.6 0.024 13.9 20.4 1.7 1 1 0 1 1 1 0 UAA transporter family 2Fe-2S_thioredx PF01257.19 PRP78979.1 - 8.3e-61 204.1 0.0 1e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin WD40 PF00400.32 PRP78980.1 - 2.2e-39 132.7 25.7 9.8e-09 35.7 0.1 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP78980.1 - 7.2e-12 45.5 3.8 0.0015 18.8 0.2 5.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP78980.1 - 1.6e-06 27.7 0.0 2e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 PRP78980.1 - 0.00022 20.0 12.8 0.14 10.8 0.2 4.4 3 1 0 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PRP78980.1 - 0.016 14.2 3.4 2.1 7.2 0.1 3.2 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 PRP78980.1 - 0.17 11.5 1.2 3.3 7.4 0.1 2.7 2 0 0 2 2 2 0 TUP1-like enhancer of split PQQ_3 PF13570.6 PRP78980.1 - 0.52 10.9 5.7 0.5 10.9 0.2 3.4 4 0 0 4 4 4 0 PQQ-like domain AAA PF00004.29 PRP78981.1 - 8.5e-43 145.9 0.0 1.6e-42 145.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 PRP78981.1 - 1.1e-23 83.1 3.1 1.1e-23 83.1 3.1 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 PRP78981.1 - 3.1e-23 81.5 0.0 1.1e-22 79.8 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 PRP78981.1 - 1.5e-06 28.7 0.1 3.1e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 PRP78981.1 - 1.7e-05 24.5 0.0 9.9e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 PRP78981.1 - 1.8e-05 24.6 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PRP78981.1 - 5.3e-05 23.2 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP78981.1 - 0.0001 22.6 0.7 0.032 14.5 0.0 2.9 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 PRP78981.1 - 0.00019 20.7 0.1 0.0004 19.7 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 PRP78981.1 - 0.00021 21.1 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 PRP78981.1 - 0.00029 20.9 0.2 0.0026 17.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 PRP78981.1 - 0.0005 19.5 0.1 0.67 9.3 0.0 2.6 1 1 1 2 2 2 2 KaiC AAA_2 PF07724.14 PRP78981.1 - 0.0005 20.2 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 PRP78981.1 - 0.00077 18.7 0.0 0.0041 16.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 PRP78981.1 - 0.00098 19.7 0.0 0.0028 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PRP78981.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PRP78981.1 - 0.0035 17.5 0.0 0.0089 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 PRP78981.1 - 0.0046 17.3 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 PRP78981.1 - 0.018 14.6 0.1 1 8.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 PRP78981.1 - 0.023 14.1 0.7 8.3 5.8 0.0 3.4 3 1 1 4 4 4 0 Bacterial TniB protein MCM PF00493.23 PRP78981.1 - 0.038 13.1 0.0 3.1 6.8 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain NACHT PF05729.12 PRP78981.1 - 0.04 13.8 0.0 0.62 10.0 0.0 2.3 1 1 0 1 1 1 0 NACHT domain DUF4037 PF13228.6 PRP78981.1 - 0.05 14.4 0.3 0.11 13.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) DUF4349 PF14257.6 PRP78981.1 - 0.051 13.0 1.4 0.34 10.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Mg_chelatase PF01078.21 PRP78981.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 PRP78981.1 - 0.056 13.9 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain SnoaL_2 PF12680.7 PRP78981.1 - 0.066 13.9 0.1 0.21 12.2 0.1 2.0 1 1 0 1 1 1 0 SnoaL-like domain PhoH PF02562.16 PRP78981.1 - 0.081 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 PRP78981.1 - 0.096 12.2 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 PRP78981.1 - 3.3 8.2 7.4 26 5.2 4.8 3.1 3 0 0 3 3 3 0 AAA domain NmrA PF05368.13 PRP78982.1 - 5.4e-20 71.9 0.0 7.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 PRP78982.1 - 8e-05 23.1 0.0 0.0002 21.8 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 PRP78982.1 - 0.00023 21.1 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PRP78982.1 - 0.0012 17.9 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PRP78982.1 - 0.0073 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Gp_dh_N PF00044.24 PRP78982.1 - 0.016 15.5 0.0 9.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 PRP78982.1 - 0.034 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GST_N PF02798.20 PRP78984.1 - 1.6e-14 54.0 0.0 4.4e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP78984.1 - 2.4e-11 43.9 0.0 5.1e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP78984.1 - 3.7e-10 39.9 0.0 1.2e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PRP78984.1 - 8.6e-09 35.6 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP78984.1 - 4.9e-08 33.1 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP78984.1 - 5.4e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1218 PF06749.12 PRP78984.1 - 0.16 12.5 1.1 15 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF4083 PF13314.6 PRP78984.1 - 0.3 11.1 3.8 0.83 9.6 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Arrestin_N PF00339.29 PRP78985.1 - 1.7e-10 41.1 0.0 1.1e-06 28.8 0.1 3.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PRP78985.1 - 5.2e-10 39.9 8.4 1.4e-09 38.5 0.0 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain SOBP PF15279.6 PRP78985.1 - 0.1 13.2 12.6 0.19 12.3 12.6 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein SMYLE_N PF18615.1 PRP78985.1 - 3.4 7.1 6.2 5.5 6.4 6.2 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Pkinase_Tyr PF07714.17 PRP78986.1 - 1.3e-108 362.2 0.0 2.6e-60 203.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP78986.1 - 3.7e-77 259.3 0.0 7.7e-45 153.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain SBBP PF06739.11 PRP78986.1 - 1.6e-05 24.8 3.7 1.6e-05 24.8 3.7 9.6 11 2 0 11 11 11 3 Beta-propeller repeat EphA2_TM PF14575.6 PRP78986.1 - 0.0012 19.7 0.1 3 8.8 0.0 2.6 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 PRP78986.1 - 0.007 15.7 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP78986.1 - 0.026 14.5 0.2 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Syndecan PF01034.20 PRP78986.1 - 5.3 7.0 6.1 2.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain PIG-H PF10181.9 PRP78988.1 - 1.1e-16 60.4 0.8 2.1e-16 59.5 0.8 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF2244 PF10003.9 PRP78988.1 - 0.058 13.1 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2058 PF09831.9 PRP78988.1 - 0.2 11.8 0.4 0.28 11.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) NUDIX PF00293.28 PRP78989.1 - 3.3e-07 30.4 0.6 9e-07 29.0 0.6 1.7 1 1 0 1 1 1 1 NUDIX domain DUF3289 PF11692.8 PRP78989.1 - 0.076 12.6 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3289) Ras PF00071.22 PRP78991.1 - 3.6e-47 160.0 0.0 5.5e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP78991.1 - 2.3e-22 79.4 0.0 3.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP78991.1 - 2.1e-05 24.1 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Lipase_GDSL_3 PF14606.6 PRP78991.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Aconitase PF00330.20 PRP78992.1 - 1.3e-151 505.7 0.0 1.6e-151 505.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 PRP78992.1 - 1.1e-46 158.4 0.2 4.4e-46 156.4 0.1 2.1 2 0 0 2 2 2 1 Aconitase C-terminal domain ADH_N_2 PF16884.5 PRP78993.1 - 1.3e-21 76.5 0.0 6.3e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 PRP78993.1 - 2.8e-19 69.4 0.0 5.9e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP78993.1 - 3.8e-09 37.7 0.0 7.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DTHCT PF08070.11 PRP78995.1 - 0.48 11.2 37.9 0.2 12.4 10.1 3.8 3 0 0 3 3 3 0 DTHCT (NUC029) region Diedel PF13164.6 PRP78996.1 - 0.1 13.1 0.8 12 6.4 0.3 2.3 1 1 1 2 2 2 0 Diedel WD40 PF00400.32 PRP78997.1 - 4.6e-14 52.6 5.4 0.085 13.8 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP78997.1 - 3.6e-05 24.0 1.0 8.1 6.8 0.0 5.4 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 PRP78997.1 - 0.067 12.5 0.4 5.2 6.3 0.0 2.6 2 1 0 2 2 2 0 CPSF A subunit region PALP PF00291.25 PRP78998.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme RBP_receptor PF14752.6 PRP78999.1 - 2.1e-13 49.7 13.9 3.1e-12 45.9 8.8 2.2 2 0 0 2 2 2 2 Retinol binding protein receptor Pox_A14 PF05767.12 PRP78999.1 - 0.1 12.7 0.1 0.1 12.7 0.1 3.5 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 PetL PF05115.14 PRP78999.1 - 1.7 8.7 6.5 2.4 8.2 0.9 3.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) GDPD PF03009.17 PRP79000.1 - 3.5e-20 72.8 0.2 1.6e-14 54.3 0.2 2.8 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family DUF4336 PF14234.6 PRP79000.1 - 5.6e-06 25.8 0.1 0.017 14.4 0.0 3.0 3 1 0 3 3 3 2 Domain of unknown function (DUF4336) Sod_Cu PF00080.20 PRP79001.1 - 6.1e-31 107.5 0.3 7.5e-31 107.2 0.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Peptidase_C48 PF02902.19 PRP79002.1 - 8.9e-06 25.7 0.5 1.9e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain PH PF00169.29 PRP79002.1 - 2.9e-05 24.5 1.0 5.8e-05 23.5 1.0 1.5 1 0 0 1 1 1 1 PH domain Sortase PF04203.13 PRP79002.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Sortase domain RTA1 PF04479.13 PRP79006.1 - 2.3e-45 154.7 4.2 3.9e-45 154.0 4.2 1.2 1 0 0 1 1 1 1 RTA1 like protein NCBP3 PF10309.9 PRP79008.1 - 2.8e-06 27.1 0.0 5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RRM_3 PF08777.11 PRP79008.1 - 0.095 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif RGS PF00615.19 PRP79010.1 - 3.2e-32 111.3 1.5 5.7e-32 110.5 0.1 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain cNMP_binding PF00027.29 PRP79010.1 - 9.4e-15 54.5 0.0 6.9e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Glyco_trans_4_4 PF13579.6 PRP79010.1 - 1.8e-08 35.0 0.2 3.6e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 PRP79010.1 - 3.7e-07 30.3 0.1 8.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 PRP79010.1 - 1.6e-06 27.8 0.0 4.2e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PRP79010.1 - 2.8e-06 27.8 0.0 5.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 GRAM PF02893.20 PRP79010.1 - 0.00021 21.1 0.5 0.00054 19.8 0.5 1.8 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 PRP79010.1 - 0.00093 18.9 1.0 0.0024 17.5 1.0 1.6 1 0 0 1 1 1 1 BAR domain RGS-like PF09128.11 PRP79010.1 - 0.0031 17.2 1.0 0.0079 15.9 0.1 2.1 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain Glyco_trans_1_2 PF13524.6 PRP79010.1 - 0.011 16.1 0.1 0.068 13.6 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferases group 1 DUF1048 PF06304.11 PRP79010.1 - 0.078 13.4 0.3 0.22 12.0 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) FTA4 PF13093.6 PRP79010.1 - 0.34 10.8 3.8 0.11 12.3 0.7 1.7 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Ank_2 PF12796.7 PRP79011.1 - 1e-70 234.3 4.0 1.2e-10 41.8 0.0 7.2 1 1 9 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79011.1 - 6.1e-38 128.7 9.1 1.9e-06 28.3 0.0 11.3 5 4 6 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP79011.1 - 6.7e-29 96.7 4.6 0.36 11.5 0.0 14.8 15 0 0 15 15 15 7 Ankyrin repeat Ank PF00023.30 PRP79011.1 - 2.8e-27 93.9 18.6 0.1 13.1 0.0 14.6 13 2 1 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 PRP79011.1 - 9.5e-26 89.5 16.1 0.0056 17.0 0.1 12.8 3 2 9 13 13 13 7 Ankyrin repeats (many copies) YlzJ PF14035.6 PRP79011.1 - 0.00011 22.3 0.3 53 4.1 0.0 6.0 6 1 1 7 7 7 0 YlzJ-like protein DUF3734 PF12536.8 PRP79011.1 - 0.0042 17.4 1.9 16 5.9 0.0 5.4 4 2 2 6 6 6 1 Patatin phospholipase HTH_13 PF11972.8 PRP79011.1 - 3.2 7.9 11.0 12 6.1 0.0 4.8 6 0 0 6 6 6 0 HTH DNA binding domain MTP18 PF10558.9 PRP79012.1 - 5.3e-58 195.8 4.6 5.3e-29 101.4 0.2 2.2 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) CCDC53 PF10152.9 PRP79013.1 - 0.00012 22.6 0.4 0.00017 22.1 0.1 1.4 1 1 1 2 2 2 1 Subunit CCDC53 of WASH complex MapZ_EC1 PF18041.1 PRP79013.1 - 0.013 15.7 0.2 0.015 15.5 0.2 1.1 1 0 0 1 1 1 0 MapZ extracellular domain 1 Imm41 PF15592.6 PRP79013.1 - 0.019 15.3 0.1 0.021 15.1 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 41 pP_pnuc_1 PF18165.1 PRP79013.1 - 0.019 14.8 0.3 0.021 14.7 0.3 1.1 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease Baculo_PEP_C PF04513.12 PRP79013.1 - 0.051 13.6 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5054 PF16477.5 PRP79015.1 - 3.9e-47 161.4 0.0 7.9e-47 160.4 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5054) WD40 PF00400.32 PRP79015.1 - 9.8e-14 51.5 7.1 3.7e-07 30.7 0.3 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP79015.1 - 0.0001 22.6 0.3 0.0057 16.9 0.2 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PIN_4 PF13638.6 PRP79016.1 - 9.3e-24 84.2 0.5 9.3e-24 84.2 0.5 1.9 2 0 0 2 2 2 1 PIN domain F-box PF00646.33 PRP79016.1 - 4e-06 26.6 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain TFIIA PF03153.13 PRP79016.1 - 2e-05 24.8 15.1 2.6e-05 24.4 15.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PIN_9 PF18477.1 PRP79016.1 - 0.0012 19.1 1.2 0.039 14.2 0.4 2.5 2 0 0 2 2 2 1 PIN like domain F-box-like PF12937.7 PRP79016.1 - 0.004 17.0 0.0 0.017 15.0 0.0 2.2 1 0 0 1 1 1 1 F-box-like CEND1 PF15677.5 PRP79016.1 - 1.9 9.0 9.1 3.1 8.3 9.1 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 SRP-alpha_N PF04086.13 PRP79016.1 - 6.4 6.6 10.2 9.6 6.0 10.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LRR_4 PF12799.7 PRP79017.1 - 1.9e-125 406.4 405.3 5.2e-06 26.7 1.9 63.7 38 15 36 77 77 77 62 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP79017.1 - 2.1e-124 405.3 413.3 9.9e-11 41.2 3.9 54.2 43 13 12 55 55 55 45 Leucine rich repeat LRRNT_2 PF08263.12 PRP79017.1 - 4.2e-15 55.8 76.0 0.0024 18.1 1.2 12.2 12 0 0 12 12 12 10 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PRP79017.1 - 0.0031 17.8 323.5 2.8 8.8 0.1 75.2 80 9 3 83 83 83 12 Leucine Rich Repeat CBM26 PF16738.5 PRP79017.1 - 3.9 7.8 4.8 4 7.8 0.2 3.5 3 0 0 3 3 3 0 Starch-binding module 26 tRNA_int_end_N2 PF12928.7 PRP79018.1 - 1.5e-10 41.1 0.0 1e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 PRP79018.1 - 1.3e-05 24.8 0.1 5.5e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Fer4_22 PF17179.4 PRP79019.1 - 0.046 14.6 2.8 9.7 7.1 0.4 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain PseudoU_synth_1 PF01416.20 PRP79022.1 - 1.7e-11 44.5 0.0 1e-06 29.2 0.0 3.3 3 0 0 3 3 3 3 tRNA pseudouridine synthase GTP_EFTU PF00009.27 PRP79023.1 - 8.6e-44 149.4 0.0 1.6e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PRP79023.1 - 6.6e-26 90.8 0.0 2.2e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PRP79023.1 - 7.9e-07 29.4 0.1 2.1e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PRP79023.1 - 0.00028 20.9 0.1 0.0018 18.3 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 PRP79023.1 - 0.72 9.7 5.5 0.27 11.0 0.2 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region CAP59_mtransfer PF11735.8 PRP79024.1 - 2.5e-55 187.8 0.0 3.9e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ResIII PF04851.15 PRP79024.1 - 0.0016 18.4 0.6 0.0085 16.1 0.2 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CopB PF05275.11 PRP79024.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) CAP59_mtransfer PF11735.8 PRP79025.1 - 3.6e-54 184.0 0.0 5.7e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CO_dh PF02552.16 PRP79025.1 - 0.059 13.1 0.4 3.9 7.2 0.0 3.0 3 0 0 3 3 3 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Lipase_3 PF01764.25 PRP79026.1 - 2.6e-35 121.4 0.0 4e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PRP79026.1 - 4.8e-05 24.1 0.1 7.9e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP79026.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 PRP79026.1 - 0.015 15.3 0.0 0.046 13.7 0.0 1.7 1 1 0 1 1 1 0 Cutinase DUF2974 PF11187.8 PRP79026.1 - 0.019 14.5 0.1 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 PRP79026.1 - 0.04 14.0 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 PRP79026.1 - 0.061 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PE-PPE PF08237.11 PRP79026.1 - 0.15 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Gly_transf_sug PF04488.15 PRP79027.1 - 1.7e-11 44.6 0.2 7.1e-11 42.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Pkinase PF00069.25 PRP79028.1 - 1.5e-68 231.0 0.1 1.4e-58 198.3 0.2 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79028.1 - 8.9e-31 107.1 0.1 1.2e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP79028.1 - 0.00043 19.7 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP79028.1 - 0.0091 15.4 0.3 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP79028.1 - 0.025 14.2 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 PRP79028.1 - 0.026 14.2 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 PRP79028.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL EXS PF03124.14 PRP79029.1 - 3.2e-76 256.8 27.4 5.1e-76 256.1 27.4 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.19 PRP79029.1 - 1.5e-30 107.4 16.3 4.5e-16 59.8 11.0 2.8 1 1 1 2 2 2 2 SPX domain DUF1765 PF08578.10 PRP79030.1 - 1.2e-17 64.5 5.1 2.2e-17 63.7 2.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) P4Ha_N PF08336.11 PRP79030.1 - 0.089 12.8 2.5 4.2 7.4 1.2 2.5 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Mei5_like PF17021.5 PRP79030.1 - 1.2 9.3 5.2 0.7 9.9 0.6 2.6 1 1 1 2 2 2 0 Putative double-strand recombination repair-like Elongin_A PF06881.11 PRP79030.1 - 5.8 7.5 7.4 1.7 9.2 3.5 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A LRR_8 PF13855.6 PRP79031.1 - 5.9e-16 58.0 29.3 2.3e-07 30.4 6.2 4.8 1 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 PRP79031.1 - 2.1e-14 53.4 29.2 5.4e-05 23.5 0.1 5.3 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PRP79031.1 - 6.3e-07 29.6 3.7 1.6e-06 28.3 3.7 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PRP79031.1 - 0.0004 20.5 30.5 6.2 7.8 0.4 8.6 9 0 0 9 9 9 5 Leucine Rich Repeat Peptidase_M48_N PF16491.5 PRP79032.1 - 0.29 11.0 3.5 0.15 11.9 1.1 1.7 1 1 1 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices DUF2070 PF09843.9 PRP79032.1 - 3.1 6.0 7.9 3.6 5.8 7.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Zn_clus PF00172.18 PRP79033.1 - 0.00015 21.8 14.1 0.00015 21.8 14.1 2.6 2 1 1 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 PRP79033.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 PAS fold cNMP_binding PF00027.29 PRP79034.1 - 3.3e-22 78.3 0.0 9.7e-11 41.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PLDc PF00614.22 PRP79034.1 - 1.5e-16 59.8 1.2 3e-10 39.8 0.3 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PRP79034.1 - 1.8e-16 60.3 0.9 8.5e-11 41.9 0.3 2.8 2 0 0 2 2 2 2 PLD-like domain RasGEF PF00617.19 PRP79034.1 - 4.1e-11 43.4 0.0 2.7e-07 31.0 0.0 3.6 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.20 PRP79034.1 - 3.4e-05 24.0 0.0 0.00016 21.9 0.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif Polysacc_lyase PF14099.6 PRP79034.1 - 0.076 12.8 0.9 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Polysaccharide lyase His_Phos_1 PF00300.22 PRP79035.1 - 1.2e-34 119.8 0.0 1.1e-27 96.9 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) RTA1 PF04479.13 PRP79036.1 - 2.4e-65 220.0 6.3 3.9e-65 219.3 6.3 1.3 1 0 0 1 1 1 1 RTA1 like protein Cas_Csa5 PF09702.10 PRP79036.1 - 0.089 13.1 0.1 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) LCE6A PF15858.5 PRP79038.1 - 0.42 11.4 7.8 13 6.6 0.0 2.5 2 1 0 2 2 2 0 Late cornified envelope protein 6A family WD40 PF00400.32 PRP79039.1 - 1.8e-16 60.2 12.8 0.016 16.1 0.0 7.8 7 1 0 7 7 7 4 WD domain, G-beta repeat F-box-like PF12937.7 PRP79039.1 - 3.3e-06 26.9 0.1 6.1e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP79039.1 - 0.00017 21.4 0.3 0.00042 20.1 0.3 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 PRP79039.1 - 0.0045 16.3 0.1 0.71 9.1 0.0 2.7 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 PRP79039.1 - 0.0095 14.6 0.5 0.15 10.6 0.1 2.2 1 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 PRP79039.1 - 0.026 14.1 1.9 0.067 12.8 1.2 2.0 1 1 1 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 PRP79039.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 F-box DUF5344 PF17279.2 PRP79042.1 - 0.088 13.4 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5344) SH3_9 PF14604.6 PRP79049.1 - 4.9e-25 87.1 1.0 6.6e-12 45.1 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PRP79049.1 - 1.5e-24 85.4 1.3 4.7e-11 42.1 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 PRP79049.1 - 1.8e-20 72.3 0.1 4.2e-09 35.9 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 PRP79049.1 - 0.00011 22.4 2.8 0.0016 18.7 0.6 2.7 2 0 0 2 2 2 1 Bacterial SH3 domain Sec2p PF06428.11 PRP79049.1 - 0.024 14.6 2.3 0.21 11.6 0.9 3.0 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Rx_N PF18052.1 PRP79049.1 - 0.11 12.7 0.6 2.6 8.4 0.1 2.5 2 0 0 2 2 2 0 Rx N-terminal domain TBCC_N PF16752.5 PRP79049.1 - 3.7 8.0 6.3 0.69 10.4 0.1 2.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain NPL PF17800.1 PRP79051.1 - 8.7e-06 26.2 0.0 1.5e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoplasmin-like domain YL1 PF05764.13 PRP79051.1 - 0.24 11.5 5.0 0.26 11.4 5.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Kri1 PF05178.12 PRP79052.1 - 1.4e-21 76.9 16.4 1.4e-21 76.9 16.4 5.9 3 2 3 6 6 6 1 KRI1-like family Kri1_C PF12936.7 PRP79052.1 - 3.4e-18 65.6 1.9 3.4e-18 65.6 1.9 4.6 5 0 0 5 5 5 1 KRI1-like family C-terminal LIN52 PF10044.9 PRP79052.1 - 0.15 12.8 0.3 0.15 12.8 0.3 3.1 3 1 0 3 3 3 0 Retinal tissue protein zf-C3H1 PF10650.9 PRP79053.1 - 8.4e-07 28.6 3.7 1.8e-06 27.6 3.7 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain TPR_14 PF13428.6 PRP79053.1 - 9.2e-06 26.1 0.3 15 6.8 0.0 6.0 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79053.1 - 0.011 15.9 0.0 1.3 9.4 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP79053.1 - 0.019 15.4 0.3 54 4.4 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TMEMspv1-c74-12 PF11044.8 PRP79054.1 - 7.6 6.6 7.3 19 5.3 0.1 3.2 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein GMC_oxred_N PF00732.19 PRP79055.1 - 4.8e-26 91.8 0.0 2e-25 89.8 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP79055.1 - 1.2e-12 48.6 0.0 2.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 PRP79055.1 - 0.00019 21.1 0.0 0.00053 19.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP79055.1 - 0.0042 17.3 0.0 0.02 15.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 PRP79055.1 - 0.18 11.0 0.0 7.5 5.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DNA_pol_B PF00136.21 PRP79057.1 - 7.7e-100 334.8 0.4 1.2e-99 334.2 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PRP79057.1 - 1.8e-21 76.6 1.6 1.2e-14 54.2 0.5 2.8 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PRP79057.1 - 9.5e-13 48.4 4.5 2.3e-12 47.2 4.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta OrfB_Zn_ribbon PF07282.11 PRP79057.1 - 0.43 10.5 2.8 1.3 9.0 2.8 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain RicinB_lectin_2 PF14200.6 PRP79058.1 - 1.3e-05 25.8 0.2 2.2e-05 25.1 0.2 1.4 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Fascin PF06268.13 PRP79058.1 - 0.02 15.1 0.0 0.031 14.5 0.0 1.4 1 1 0 1 1 1 0 Fascin domain fn3_3 PF14686.6 PRP79058.1 - 0.1 12.4 0.0 4.1 7.3 0.1 2.4 1 1 1 2 2 2 0 Polysaccharide lyase family 4, domain II DNA_pol_E_B PF04042.16 PRP79059.1 - 2e-43 148.2 0.8 3e-43 147.6 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.7 PRP79059.1 - 0.0047 17.1 0.0 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 PRP79059.1 - 0.038 14.5 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase HECT PF00632.25 PRP79060.1 - 1.1e-85 287.8 0.1 1.9e-85 287.0 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 PRP79060.1 - 2.2e-85 281.1 5.9 6.2e-16 58.8 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP79060.1 - 2.9e-39 132.1 24.6 1.8e-09 37.2 1.3 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat HTH_32 PF13565.6 PRP79060.1 - 0.16 12.6 0.0 0.59 10.8 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain DUF5359 PF17313.2 PRP79060.1 - 0.3 11.1 0.9 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5359) ABC_tran PF00005.27 PRP79061.1 - 2e-21 77.0 0.0 2e-21 77.0 0.0 2.7 2 0 0 2 2 1 1 ABC transporter ABC2_membrane PF01061.24 PRP79061.1 - 1.1e-15 57.6 22.5 2.3e-15 56.6 22.5 1.6 1 0 0 1 1 1 1 ABC-2 type transporter PSI PF01437.25 PRP79061.1 - 0.0001 22.8 71.1 0.15 12.6 0.9 7.4 7 0 0 7 7 6 5 Plexin repeat LRR_6 PF13516.6 PRP79061.1 - 0.0047 16.9 2.4 50 4.3 0.0 5.9 6 0 0 6 6 5 0 Leucine Rich repeat AAA_16 PF13191.6 PRP79061.1 - 0.011 16.1 0.0 0.036 14.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane_3 PF12698.7 PRP79061.1 - 0.028 13.5 19.4 0.059 12.5 19.4 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein RsgA_GTPase PF03193.16 PRP79061.1 - 0.048 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 PRP79061.1 - 0.058 13.0 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PRP79061.1 - 0.067 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PRP79061.1 - 0.076 13.5 0.0 0.076 13.5 0.0 3.4 2 1 1 3 3 1 0 AAA domain RNA_helicase PF00910.22 PRP79061.1 - 0.083 13.3 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 PRP79061.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 PRP79061.1 - 0.16 11.8 0.4 0.35 10.7 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 PRP79061.1 - 3.8 7.2 12.3 44 3.7 0.0 4.2 4 1 1 5 5 4 0 AAA domain, putative AbiEii toxin, Type IV TA system NmrA PF05368.13 PRP79062.1 - 6e-18 65.2 0.1 8.2e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP79062.1 - 1.5e-12 47.8 0.0 3e-12 46.8 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 PRP79062.1 - 0.00015 21.3 0.0 0.00028 20.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 PRP79062.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TcdB_toxin_midN PF12256.8 PRP79062.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region RmlD_sub_bind PF04321.17 PRP79062.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.20 PRP79062.1 - 0.08 13.1 0.0 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF4187 PF13821.6 PRP79063.1 - 4.2e-12 45.7 1.2 1.2e-11 44.2 1.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 PRP79063.1 - 7.2e-09 35.4 0.6 4.5e-07 29.7 0.1 2.4 2 0 0 2 2 2 2 G-patch domain G-patch_2 PF12656.7 PRP79063.1 - 0.00013 22.0 1.7 0.00026 21.0 0.7 2.1 1 1 1 2 2 2 1 G-patch domain AKNA PF12443.8 PRP79065.1 - 0.016 15.8 0.2 0.02 15.5 0.2 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor PspB PF06667.12 PRP79065.1 - 0.46 10.6 2.5 23 5.2 0.0 2.2 2 0 0 2 2 2 0 Phage shock protein B Glyco_hydro_cc PF11790.8 PRP79066.1 - 1.1e-69 234.7 0.1 1.7e-69 234.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core X8 PF07983.13 PRP79066.1 - 1.3e-12 48.2 2.0 3.5e-12 46.8 2.0 1.7 1 0 0 1 1 1 1 X8 domain CorA PF01544.18 PRP79066.1 - 0.00023 20.6 3.5 0.00044 19.7 3.5 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein VID27 PF08553.10 PRP79068.1 - 4.3e-97 325.4 0.1 7.6e-97 324.5 0.1 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 PRP79068.1 - 8.8e-10 38.8 0.1 2.3e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 VID27 PH-like domain VID27_N PF17748.1 PRP79068.1 - 0.0029 17.5 12.0 0.13 12.1 0.1 4.5 2 2 3 5 5 5 2 VID27 N-terminal region BTB PF00651.31 PRP79069.1 - 1.7e-15 57.2 0.1 4.7e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 PRP79069.1 - 1.4e-05 25.1 1.0 0.00047 20.2 0.2 2.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF627 PF04781.12 PRP79069.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Arm_2 PF04826.13 PRP79069.1 - 0.065 12.7 1.4 0.13 11.7 0.1 2.1 2 1 1 3 3 3 0 Armadillo-like DUF3120 PF11318.8 PRP79069.1 - 0.15 12.4 0.2 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) RhoGAP PF00620.27 PRP79070.1 - 8.3e-67 223.7 0.0 1.6e-25 89.7 0.0 3.8 3 0 0 3 3 3 3 RhoGAP domain FERM_N PF09379.10 PRP79070.1 - 0.00013 21.8 0.4 0.13 12.2 0.0 3.0 3 0 0 3 3 3 2 FERM N-terminal domain TUG-UBL1 PF11470.8 PRP79070.1 - 0.00048 20.3 0.0 0.59 10.4 0.0 2.6 2 0 0 2 2 2 2 TUG ubiquitin-like domain RA PF00788.23 PRP79070.1 - 0.001 19.7 0.0 0.074 13.7 0.0 2.5 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain Rad60-SLD PF11976.8 PRP79070.1 - 0.0022 17.8 0.0 0.48 10.3 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Gemini_mov PF01708.16 PRP79071.1 - 0.016 14.9 0.8 0.037 13.8 0.1 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF4577 PF15145.6 PRP79071.1 - 0.033 14.2 0.8 1 9.4 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4577) Pkinase_Tyr PF07714.17 PRP79074.1 - 3.7e-55 187.0 0.1 6.2e-55 186.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79074.1 - 1e-37 129.9 0.5 9.7e-36 123.5 0.1 2.7 2 1 0 2 2 2 1 Protein kinase domain Ras PF00071.22 PRP79074.1 - 3.9e-37 127.4 0.0 7.9e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Ras family TIG PF01833.24 PRP79074.1 - 5.4e-20 71.3 61.5 0.0001 22.3 0.4 10.0 9 0 0 9 9 9 7 IPT/TIG domain Roc PF08477.13 PRP79074.1 - 1.5e-19 70.4 0.0 3.8e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GPS PF01825.21 PRP79074.1 - 4.2e-05 24.0 3.8 4.2e-05 24.0 3.8 2.8 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP79074.1 - 0.00022 20.7 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP79074.1 - 0.0061 15.9 0.2 0.021 14.1 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 PRP79074.1 - 0.022 14.3 1.4 0.067 12.7 0.0 2.4 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 PRP79074.1 - 0.068 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP79074.1 - 0.079 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 PRP79074.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF5527 PF17665.1 PRP79074.1 - 0.24 10.9 0.6 0.47 10.0 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5527) Pkinase PF00069.25 PRP79075.1 - 6.3e-44 150.3 0.0 7.6e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79075.1 - 1.7e-15 57.1 0.0 2.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP79075.1 - 1.5e-06 28.4 0.3 0.024 14.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP79075.1 - 5.6e-06 25.9 0.0 7.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP79075.1 - 1.5e-05 24.5 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OSK PF17182.4 PRP79075.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 OSK domain FAD_binding_3 PF01494.19 PRP79076.1 - 2.6e-76 257.1 0.0 3.6e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 PRP79076.1 - 1.6e-42 145.4 0.0 3.4e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 PRP79076.1 - 0.0032 17.7 0.0 0.009 16.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PRP79076.1 - 0.0047 15.7 0.0 0.007 15.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 PRP79076.1 - 0.0066 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 PRP79076.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP79076.1 - 0.025 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 PRP79076.1 - 0.028 13.5 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein SE PF08491.10 PRP79076.1 - 0.046 12.8 0.1 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.27 PRP79076.1 - 0.056 14.0 0.0 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP79076.1 - 0.083 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP79076.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase APG6 PF04111.12 PRP79077.1 - 3.8e-60 202.9 0.8 1.1e-59 201.4 0.0 2.1 2 1 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 PRP79077.1 - 1.2e-13 51.7 19.4 2e-13 51.0 19.4 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region V_ATPase_I PF01496.19 PRP79077.1 - 0.16 9.9 4.4 0.21 9.5 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 PRP79077.1 - 0.85 10.3 7.7 2.2 9.0 7.7 1.7 1 0 0 1 1 1 0 Initiation control protein YabA FapA PF03961.13 PRP79077.1 - 5.3 5.5 6.7 7.5 5.0 6.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1192 PF06698.11 PRP79077.1 - 5.3 7.2 15.1 0.46 10.6 4.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Sterol-sensing PF12349.8 PRP79078.1 - 0.0061 16.4 4.2 0.0061 16.4 4.2 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Herpes_US9 PF06072.11 PRP79078.1 - 0.1 12.5 4.7 3.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Ctr PF04145.15 PRP79078.1 - 0.1 13.2 1.4 0.18 12.5 1.1 1.6 1 1 0 1 1 1 0 Ctr copper transporter family Tweety PF04906.13 PRP79078.1 - 0.15 10.6 4.8 0.19 10.4 0.5 2.0 2 0 0 2 2 2 0 Tweety DUF4149 PF13664.6 PRP79078.1 - 0.57 10.5 0.0 0.57 10.5 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) GILT PF03227.16 PRP79079.1 - 7.3e-09 35.8 0.8 7.3e-09 35.8 0.8 2.4 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Peripla_BP_7 PF18610.1 PRP79079.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Sec7 PF01369.20 PRP79080.1 - 5e-63 212.1 0.4 2.1e-62 210.1 0.1 2.3 2 0 0 2 2 2 1 Sec7 domain UCH PF00443.29 PRP79080.1 - 7.6e-51 173.1 17.3 6e-21 75.1 0.6 5.0 5 0 0 5 5 5 3 Ubiquitin carboxyl-terminal hydrolase Sec7_N PF12783.7 PRP79080.1 - 1.5e-42 145.2 1.5 1.5e-42 145.2 1.5 3.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 PRP79080.1 - 9e-34 115.2 0.3 9e-34 115.2 0.3 6.0 8 0 0 8 8 8 1 Domain of unknown function (DUF1981) DCB PF16213.5 PRP79080.1 - 5.6e-33 114.1 6.1 3.3e-29 101.8 2.0 4.7 3 0 0 3 3 3 3 Dimerisation and cyclophilin-binding domain of Mon2 UCH_1 PF13423.6 PRP79080.1 - 1.6e-16 60.8 12.2 1.6e-05 24.7 0.2 4.3 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase U3snoRNP10 PF12397.8 PRP79080.1 - 0.043 14.2 0.9 25 5.3 0.0 4.1 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Glyco_tran_WbsX PF14307.6 PRP79080.1 - 0.057 12.9 0.1 0.23 10.9 0.1 2.0 1 0 0 1 1 1 0 Glycosyltransferase WbsX Pput2613-deam PF14427.6 PRP79080.1 - 1.5 8.7 3.8 85 3.1 0.1 3.5 3 0 0 3 3 3 0 Pput_2613-like deaminase PreAtp-grasp PF18604.1 PRP79081.1 - 0.017 14.8 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Pre ATP-grasp domain PapC_N PF13954.6 PRP79081.1 - 0.047 13.7 0.4 2.4 8.1 0.1 2.5 1 1 1 2 2 2 0 PapC N-terminal domain TubC_N PF18563.1 PRP79081.1 - 0.065 13.2 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 TubC N-terminal docking domain MSP7_C PF12948.7 PRP79081.1 - 0.12 13.0 0.1 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain AMP-binding PF00501.28 PRP79082.1 - 8.4e-82 275.0 0.1 1.6e-80 270.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme DEAD PF00270.29 PRP79082.1 - 1.7e-06 27.9 0.4 1.5e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PRP79082.1 - 0.0012 19.2 1.0 0.002 18.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP79082.1 - 0.003 17.8 0.0 0.015 15.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP79082.1 - 0.0043 16.8 0.1 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 PRP79082.1 - 0.0085 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain SPX PF03105.19 PRP79083.1 - 0.37 10.7 6.1 0.47 10.3 6.1 1.0 1 0 0 1 1 1 0 SPX domain DUF4834 PF16118.5 PRP79083.1 - 3.1 8.8 5.7 1.5 9.8 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Kinesin_assoc PF16183.5 PRP79083.1 - 5.6 7.1 6.7 1.8 8.7 3.6 1.6 2 0 0 2 2 2 0 Kinesin-associated DUF1180 PF06679.12 PRP79083.1 - 6.2 7.2 8.9 2.6 8.4 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CLN3 PF02487.17 PRP79084.1 - 9.3e-98 327.9 25.4 3.7e-96 322.6 25.4 2.0 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 PRP79084.1 - 8e-06 25.0 31.2 0.022 13.7 14.6 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily FPN1 PF06963.12 PRP79084.1 - 0.012 14.3 1.8 0.013 14.0 0.0 1.9 2 0 0 2 2 2 0 Ferroportin1 (FPN1) DUF3043 PF11241.8 PRP79084.1 - 1.1 9.2 2.1 1.9 8.5 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3043) VKOR PF07884.14 PRP79085.1 - 2.7e-24 85.7 13.9 2.7e-24 85.7 13.9 2.0 2 0 0 2 2 2 1 Vitamin K epoxide reductase family Meckelin PF09773.9 PRP79085.1 - 0.077 11.1 4.0 0.065 11.3 0.3 2.0 1 1 1 2 2 2 0 Meckelin (Transmembrane protein 67) Pkinase PF00069.25 PRP79086.1 - 3.1e-73 246.4 0.0 3.7e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79086.1 - 3.2e-35 121.7 0.1 5.4e-35 120.9 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP79086.1 - 1.4e-05 24.6 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP79086.1 - 0.0002 20.4 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP79086.1 - 0.0076 16.2 0.6 0.18 11.7 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP79086.1 - 0.039 13.6 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 RIO1 family MscL PF01741.18 PRP79087.1 - 1.4e-30 106.0 1.0 2.3e-30 105.4 1.0 1.3 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL MAPKK1_Int PF08923.10 PRP79087.1 - 0.0071 16.1 0.3 0.019 14.8 0.1 1.8 2 0 0 2 2 2 1 Mitogen-activated protein kinase kinase 1 interacting Laminin_EGF PF00053.24 PRP79088.1 - 9.5e-16 57.7 82.7 0.00053 20.1 12.3 5.8 3 2 2 5 5 5 5 Laminin EGF domain EGF_2 PF07974.13 PRP79088.1 - 0.00033 20.9 5.0 0.00033 20.9 5.0 7.8 7 1 0 7 7 7 3 EGF-like domain EGF PF00008.27 PRP79088.1 - 1.4 9.3 52.6 0.11 12.8 6.0 6.6 5 0 0 5 5 5 0 EGF-like domain DUF2757 PF10955.8 PRP79090.1 - 0.048 13.9 0.2 15 5.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) Ala_racemase_N PF01168.20 PRP79090.1 - 0.056 13.1 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain DUF4518 PF15008.6 PRP79090.1 - 0.079 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) zinc-ribbons_6 PF07191.12 PRP79090.1 - 0.18 11.8 1.2 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-ACC PF17848.1 PRP79090.1 - 0.31 11.2 2.3 5.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn-ribbon_8 PF09723.10 PRP79090.1 - 0.87 9.8 4.4 11 6.3 0.0 3.0 3 0 0 3 3 3 0 Zinc ribbon domain GRAM PF02893.20 PRP79091.1 - 0.031 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 GRAM domain MORN PF02493.20 PRP79093.1 - 9e-28 94.5 21.5 4.3e-07 29.4 0.5 5.7 6 0 0 6 6 6 5 MORN repeat Gln-synt_C-ter PF18318.1 PRP79093.1 - 3.6 7.5 4.0 11 5.8 0.2 2.4 1 1 1 2 2 2 0 Glutamine synthetase C-terminal domain RhoGEF PF00621.20 PRP79094.1 - 1.5e-65 220.8 10.0 5.9e-47 160.3 4.4 2.6 2 0 0 2 2 2 2 RhoGEF domain BTB PF00651.31 PRP79094.1 - 1.7e-09 37.9 0.3 4.4e-09 36.6 0.3 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF3632 PF12311.8 PRP79094.1 - 0.056 13.9 0.2 0.6 10.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3632) CPSF100_C PF13299.6 PRP79094.1 - 0.31 11.2 7.7 3.2 7.9 0.1 3.4 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Paramyxo_ncap PF00973.19 PRP79095.1 - 0.46 9.3 3.6 0.66 8.8 3.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Tmemb_cc2 PF10267.9 PRP79095.1 - 0.47 9.6 4.5 0.12 11.4 1.5 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein LegC3_N PF18654.1 PRP79096.1 - 0.0051 16.1 0.2 0.0051 16.1 0.2 2.0 1 1 0 2 2 2 1 LegC3 N-terminal coiled-coil domain UVR PF02151.19 PRP79096.1 - 0.061 13.1 0.3 0.061 13.1 0.3 2.5 2 0 0 2 2 2 0 UvrB/uvrC motif RasGAP PF00616.19 PRP79097.1 - 8.6e-19 68.1 0.0 2.9e-10 40.2 0.0 3.1 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase START PF01852.19 PRP79097.1 - 1e-05 25.0 0.0 1.7e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 START domain C_Hendra PF16821.5 PRP79097.1 - 0.12 12.3 1.9 0.25 11.2 1.9 1.5 1 0 0 1 1 1 0 C protein from hendra and measles viruses zf-RING_2 PF13639.6 PRP79098.1 - 7e-12 45.5 5.7 1.5e-11 44.4 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP79098.1 - 2.2e-10 40.2 6.2 4.6e-10 39.2 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP79098.1 - 5.5e-09 35.6 2.6 1.4e-08 34.3 2.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 PRP79098.1 - 1.3e-08 34.7 3.7 2.7e-08 33.6 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PRP79098.1 - 8.4e-08 32.4 9.4 1.3e-07 31.8 6.9 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP79098.1 - 8.3e-07 28.9 2.9 1.8e-06 27.9 2.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP79098.1 - 1.8e-06 27.7 3.5 3.5e-06 26.8 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP79098.1 - 3e-06 27.0 4.2 5.9e-06 26.0 4.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PRP79098.1 - 4.1e-06 26.5 5.5 7.9e-06 25.6 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PRP79098.1 - 1.2e-05 24.8 5.1 2.4e-05 23.9 5.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 PRP79098.1 - 1.2e-05 25.2 2.6 8.1e-05 22.6 1.5 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PRP79098.1 - 0.0017 18.5 2.1 0.021 15.0 2.7 2.5 2 0 0 2 2 2 1 FANCL C-terminal domain Baculo_RING PF05883.11 PRP79098.1 - 0.0021 18.0 0.3 0.0051 16.8 0.3 1.6 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.6 PRP79098.1 - 0.021 14.6 3.5 0.045 13.5 3.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 PRP79098.1 - 0.056 13.6 4.9 0.12 12.5 4.9 1.6 1 0 0 1 1 1 0 RING-variant domain DUF2921 PF11145.8 PRP79098.1 - 0.16 9.8 1.6 0.31 8.8 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2921) zf-RING-like PF08746.11 PRP79098.1 - 0.17 12.2 3.6 0.44 10.9 3.6 1.8 1 0 0 1 1 1 0 RING-like domain zf-Nse PF11789.8 PRP79098.1 - 0.38 10.6 3.1 0.81 9.5 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 PRP79098.1 - 2 8.5 3.9 4.4 7.4 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 PRP79098.1 - 2 8.6 6.0 5.8 7.2 6.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ATG27 PF09451.10 PRP79099.1 - 1.6e-17 64.2 0.0 2.8e-08 33.9 0.0 2.7 2 2 0 2 2 2 2 Autophagy-related protein 27 Man-6-P_recep PF02157.15 PRP79099.1 - 2.1e-16 59.8 0.2 2.4e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 Mannose-6-phosphate receptor DUF3093 PF11292.8 PRP79099.1 - 0.0083 16.4 0.9 3.2 8.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3093) Autophagy_act_C PF03987.15 PRP79099.1 - 0.0094 16.5 0.0 7.2 7.3 0.0 2.6 2 0 0 2 2 2 2 Autophagocytosis associated protein, active-site domain DUF347 PF03988.12 PRP79099.1 - 0.018 15.2 5.1 0.88 9.8 0.5 2.7 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) RepA1_leader PF08048.12 PRP79099.1 - 0.075 13.3 6.2 0.28 11.5 0.7 2.7 2 0 0 2 2 2 0 Tap RepA1 leader peptide DUF1201 PF06716.11 PRP79099.1 - 3.4 7.7 8.8 5.6 7.1 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Rad9 PF04139.13 PRP79100.1 - 6.8e-71 238.6 0.5 8e-71 238.4 0.5 1.0 1 0 0 1 1 1 1 Rad9 PCNA_N PF00705.18 PRP79100.1 - 0.03 14.0 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain SPX PF03105.19 PRP79100.1 - 0.5 10.2 4.0 0.61 10.0 4.0 1.2 1 0 0 1 1 1 0 SPX domain QWRF PF04484.12 PRP79100.1 - 7.5 6.2 10.8 13 5.4 10.8 1.3 1 0 0 1 1 1 0 QWRF family MtN3_slv PF03083.16 PRP79101.1 - 4.4e-08 33.0 5.9 5e-06 26.5 0.4 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Imp-YgjV PF10688.9 PRP79101.1 - 0.24 11.2 11.6 4.8 7.0 0.3 3.5 2 1 1 3 3 3 0 Bacterial inner membrane protein DUF3792 PF12670.7 PRP79101.1 - 3.1 8.0 7.4 1.1 9.4 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) Pkinase_Tyr PF07714.17 PRP79102.1 - 2.8e-28 98.9 2.4 4.6e-27 94.9 0.6 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP79102.1 - 4.4e-24 85.3 1.8 9.4e-24 84.2 1.8 1.4 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP79102.1 - 1.2e-19 69.8 39.4 9.7e-08 31.7 8.6 5.8 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 PRP79102.1 - 5.5e-10 39.3 48.3 0.0083 16.5 2.3 7.8 5 2 4 9 9 9 7 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP79102.1 - 5.9e-07 29.9 0.1 1.3e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP79102.1 - 0.0016 17.8 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 Kinase-like GNVR PF13807.6 PRP79102.1 - 0.062 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase ATE_N PF04376.13 PRP79102.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, N terminus LRR_1 PF00560.33 PRP79102.1 - 9 7.3 44.0 2.2 9.2 0.4 11.8 11 2 1 12 12 12 0 Leucine Rich Repeat Lipoprotein_15 PF03640.15 PRP79104.1 - 0.084 12.4 0.1 19 4.9 0.0 2.6 2 0 0 2 2 2 0 Secreted repeat of unknown function RANK_CRD_2 PF18278.1 PRP79104.1 - 0.12 12.6 2.2 10 6.3 0.1 2.4 2 0 0 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Pkinase_Tyr PF07714.17 PRP79105.1 - 8.4e-77 257.9 0.0 2.2e-76 256.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79105.1 - 1.3e-54 185.3 0.0 2.4e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP79105.1 - 5.5e-22 77.3 45.8 1.9e-10 40.3 6.8 8.9 6 3 4 10 10 10 6 Leucine rich repeat LRR_4 PF12799.7 PRP79105.1 - 3.5e-21 74.9 56.6 0.00076 19.8 0.7 10.6 6 3 6 13 13 12 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP79105.1 - 1e-06 28.4 10.7 0.095 12.2 0.3 5.4 2 1 2 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 PRP79105.1 - 2.2e-06 27.4 35.2 3.7 8.5 0.2 13.4 13 3 0 13 13 11 2 Leucine Rich Repeat Kdo PF06293.14 PRP79105.1 - 0.00065 19.1 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP79105.1 - 0.0015 17.4 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase SKG6 PF08693.10 PRP79105.1 - 0.022 14.1 3.8 0.022 14.2 1.4 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Haspin_kinase PF12330.8 PRP79105.1 - 0.03 13.3 0.1 0.2 10.5 0.1 2.1 1 1 0 1 1 1 0 Haspin like kinase domain LRR_6 PF13516.6 PRP79105.1 - 0.35 11.0 0.0 0.35 11.0 0.0 12.9 16 0 0 16 16 16 0 Leucine Rich repeat X8 PF07983.13 PRP79106.1 - 1e-49 167.1 47.5 2.3e-08 34.6 2.1 6.6 6 0 0 6 6 6 6 X8 domain Glyco_hydro_17 PF00332.18 PRP79106.1 - 3.2e-05 23.7 2.0 5.3e-05 23.0 0.9 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF2989 PF11207.8 PRP79106.1 - 0.00047 20.0 2.9 3.4 7.4 0.0 5.4 6 0 0 6 6 6 1 Protein of unknown function (DUF2989) DUF226 PF02890.14 PRP79106.1 - 0.17 11.9 2.0 8.8 6.3 0.0 3.2 4 0 0 4 4 4 0 Borrelia family of unknown function DUF226 MFS_1 PF07690.16 PRP79107.1 - 4.6e-27 94.9 64.2 1.7e-19 70.0 43.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.22 PRP79107.1 - 4e-25 88.3 0.0 6.1e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79107.1 - 2.8e-06 27.5 0.0 7.6e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Virulence_fact PF13769.6 PRP79107.1 - 0.065 13.5 0.5 0.18 12.1 0.2 1.8 2 0 0 2 2 2 0 Virulence factor GFO_IDH_MocA PF01408.22 PRP79109.1 - 5.7e-23 82.0 0.0 8.9e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PRP79109.1 - 0.0021 18.1 0.0 0.0062 16.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain TFIIF_alpha PF05793.12 PRP79110.1 - 0.029 13.0 15.2 0.035 12.7 15.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4407 PF14362.6 PRP79110.1 - 0.51 9.6 6.4 0.69 9.2 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CobT PF06213.12 PRP79110.1 - 0.87 8.9 12.8 1.2 8.4 12.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 PRP79110.1 - 2.4 7.1 5.2 3.2 6.7 5.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 PRP79110.1 - 4.9 6.3 5.4 7.1 5.7 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 PRP79110.1 - 5.7 4.9 14.5 9 4.3 14.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi PAC1 PF16094.5 PRP79110.1 - 6.1 5.9 6.9 11 5.1 6.9 1.5 1 1 0 1 1 1 0 Proteasome assembly chaperone 4 Presenilin PF01080.17 PRP79110.1 - 7.8 5.2 8.2 9.7 4.8 8.2 1.1 1 0 0 1 1 1 0 Presenilin YabA PF06156.13 PRP79111.1 - 6.8e-05 23.4 3.5 0.00021 21.9 3.5 1.9 1 0 0 1 1 1 1 Initiation control protein YabA Laminin_I PF06008.14 PRP79111.1 - 0.00048 19.9 2.4 0.00077 19.2 2.4 1.3 1 0 0 1 1 1 1 Laminin Domain I KASH_CCD PF14662.6 PRP79111.1 - 0.0023 17.8 6.8 0.0051 16.7 6.8 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Ax_dynein_light PF10211.9 PRP79111.1 - 0.0039 17.2 6.8 0.0039 17.2 6.8 1.8 2 0 0 2 2 2 1 Axonemal dynein light chain K-box PF01486.17 PRP79111.1 - 0.0063 16.7 6.8 0.026 14.7 1.8 2.6 2 0 0 2 2 2 1 K-box region Yuri_gagarin PF15934.5 PRP79111.1 - 0.008 16.0 6.0 2.2 8.0 3.8 2.2 2 0 0 2 2 2 2 Yuri gagarin ADIP PF11559.8 PRP79111.1 - 0.01 15.9 7.5 0.01 15.9 7.5 1.7 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 PRP79111.1 - 0.016 15.2 3.7 0.016 15.2 3.7 2.3 2 1 0 2 2 1 0 FlxA-like protein DivIC PF04977.15 PRP79111.1 - 0.017 14.9 1.4 0.017 14.9 1.4 2.9 2 1 1 3 3 2 0 Septum formation initiator TSC22 PF01166.18 PRP79111.1 - 0.021 15.1 4.9 1.4 9.3 1.0 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family HALZ PF02183.18 PRP79111.1 - 0.031 14.5 2.2 0.031 14.5 2.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.11 PRP79111.1 - 0.049 12.5 13.7 0.014 14.3 10.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 PRP79111.1 - 0.052 13.6 10.2 0.19 11.9 2.3 2.9 1 1 1 2 2 2 0 bZIP transcription factor Golgin_A5 PF09787.9 PRP79111.1 - 0.057 12.9 11.8 0.02 14.4 8.7 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 Hemerythrin PF01814.23 PRP79111.1 - 0.063 13.9 0.1 0.15 12.7 0.1 1.6 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Exonuc_VII_L PF02601.15 PRP79111.1 - 0.34 10.5 5.1 0.58 9.7 5.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lectin_N PF03954.14 PRP79111.1 - 0.37 10.5 3.7 0.47 10.2 1.3 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Prominin PF05478.11 PRP79111.1 - 0.42 8.5 2.1 0.73 7.7 2.1 1.3 1 0 0 1 1 1 0 Prominin LCD1 PF09798.9 PRP79111.1 - 2 6.8 9.1 2.5 6.5 9.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein UPF0449 PF15136.6 PRP79111.1 - 2 8.9 10.1 0.097 13.2 1.6 2.8 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 TMPIT PF07851.13 PRP79111.1 - 2.2 7.5 6.1 4.1 6.6 6.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein bZIP_2 PF07716.15 PRP79111.1 - 3.5 7.8 10.3 0.93 9.6 3.2 2.9 3 0 0 3 3 2 0 Basic region leucine zipper TPR_MLP1_2 PF07926.12 PRP79111.1 - 4.1 7.5 15.0 0.16 12.1 8.6 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.6 PRP79112.1 - 3.8e-05 23.6 0.4 0.00011 22.2 0.4 1.7 1 0 0 1 1 1 1 FlxA-like protein CCDC144C PF14915.6 PRP79112.1 - 0.00013 21.2 3.1 0.00025 20.3 3.1 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region GAS PF13851.6 PRP79112.1 - 0.0002 20.8 4.1 0.00054 19.4 4.1 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding RasGAP_C PF03836.15 PRP79112.1 - 0.00071 19.7 0.9 0.0013 18.8 0.9 1.4 1 0 0 1 1 1 1 RasGAP C-terminus bZIP_1 PF00170.21 PRP79112.1 - 0.0014 18.7 1.3 1.7 8.8 0.2 2.7 2 0 0 2 2 2 2 bZIP transcription factor Uso1_p115_C PF04871.13 PRP79112.1 - 0.0094 16.3 3.8 0.0094 16.3 3.8 3.0 2 1 1 3 3 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 PRP79112.1 - 0.012 15.7 1.0 0.027 14.5 1.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.6 PRP79112.1 - 0.015 15.4 2.0 0.14 12.2 0.2 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TolA_bind_tri PF16331.5 PRP79112.1 - 0.015 15.4 4.5 0.35 11.0 1.0 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation GIT_CC PF16559.5 PRP79112.1 - 0.023 14.5 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FapA PF03961.13 PRP79112.1 - 0.039 12.6 0.6 0.058 12.0 0.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A KASH_CCD PF14662.6 PRP79112.1 - 0.063 13.1 2.7 0.18 11.6 2.7 1.6 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 PRP79112.1 - 0.073 13.4 0.5 4.6 7.6 0.1 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 PRP79112.1 - 0.089 12.6 4.0 0.38 10.6 0.2 2.6 1 1 1 2 2 2 0 Septum formation initiator Csm1_N PF18504.1 PRP79112.1 - 0.17 12.3 3.7 0.58 10.5 0.6 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain ZapB PF06005.12 PRP79112.1 - 0.81 10.2 5.3 5.1 7.6 5.2 2.3 1 1 0 1 1 1 0 Cell division protein ZapB BST2 PF16716.5 PRP79112.1 - 1.2 9.8 5.5 0.93 10.1 0.9 2.4 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 PRP79112.1 - 1.6 9.4 4.7 1.5 9.5 2.0 2.3 2 1 0 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 PRP79114.1 - 1.8e-66 224.2 0.0 3.2e-65 220.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79114.1 - 8.1e-41 140.0 0.0 1.7e-40 139.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP79114.1 - 5.2e-05 22.7 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP79114.1 - 0.0003 19.7 0.0 0.00099 18.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP79114.1 - 0.00083 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP79114.1 - 0.00095 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP79114.1 - 0.014 14.3 1.4 0.063 12.2 0.0 2.4 3 0 0 3 3 3 0 Haspin like kinase domain FTA2 PF13095.6 PRP79114.1 - 0.053 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 PRP79114.1 - 0.11 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Abhydrolase_6 PF12697.7 PRP79116.1 - 1.9e-13 51.5 1.3 2.8e-13 51.0 0.8 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP79116.1 - 1.5e-10 41.2 0.1 1.6e-09 37.8 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP79116.1 - 5.5e-10 38.9 0.1 1.3e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 GCS PF03074.16 PRP79117.1 - 6.3e-139 463.4 0.2 1.7e-138 462.0 0.2 1.6 1 1 0 1 1 1 1 Glutamate-cysteine ligase RabGAP-TBC PF00566.18 PRP79118.1 - 7.5e-52 176.1 0.6 1.2e-51 175.4 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PerC PF06069.11 PRP79118.1 - 0.032 14.5 0.1 0.073 13.3 0.1 1.5 1 0 0 1 1 1 0 PerC transcriptional activator Flu_NP PF00506.18 PRP79118.1 - 0.054 12.1 0.0 0.089 11.4 0.0 1.2 1 0 0 1 1 1 0 Influenza virus nucleoprotein DUF3220 PF11516.8 PRP79118.1 - 0.064 13.5 0.3 0.97 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) SAP PF02037.27 PRP79119.1 - 2.4e-10 39.9 1.4 5.1e-10 38.9 1.4 1.5 1 0 0 1 1 1 1 SAP domain Nop14 PF04147.12 PRP79119.1 - 0.1 10.8 29.7 0.19 9.9 29.7 1.3 1 0 0 1 1 1 0 Nop14-like family Cut8 PF08559.10 PRP79119.1 - 0.61 9.6 16.0 24 4.4 16.0 2.6 1 1 0 1 1 1 0 Cut8, nuclear proteasome tether protein PIEZO PF15917.5 PRP79119.1 - 8.5 5.8 13.6 20 4.6 13.6 1.6 1 0 0 1 1 1 0 Piezo DUF938 PF06080.12 PRP79120.1 - 1.8e-46 158.5 0.0 2.1e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 PRP79120.1 - 0.0014 18.5 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP79120.1 - 0.0022 18.7 0.0 0.0076 16.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP79120.1 - 0.025 15.3 0.0 0.047 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 PRP79120.1 - 0.051 13.0 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 PRP79120.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Solute_trans_a PF03619.16 PRP79122.1 - 3.6e-84 282.4 25.5 5.1e-84 281.9 25.5 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PH PF00169.29 PRP79122.1 - 7.4e-12 45.7 0.1 1.8e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PRP79122.1 - 7.6e-06 26.1 0.4 3.2e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 PRP79122.1 - 0.0004 20.7 0.0 0.00088 19.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain MG1 PF17790.1 PRP79122.1 - 0.14 12.6 0.0 0.39 11.2 0.0 1.8 1 0 0 1 1 1 0 Macroglobulin domain MG1 DIM PF08194.12 PRP79123.1 - 0.18 12.0 3.0 0.55 10.5 3.0 1.9 1 0 0 1 1 1 0 DIM protein DNA_pol_B_palm PF14792.6 PRP79124.1 - 0.044 14.0 0.1 0.061 13.5 0.1 1.4 1 1 0 1 1 1 0 DNA polymerase beta palm Suv3_N PF18114.1 PRP79124.1 - 0.089 12.9 0.1 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Suv3 helical N-terminal domain Matrilin_ccoil PF10393.9 PRP79124.1 - 0.099 12.5 0.7 1.7 8.6 0.0 2.4 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin AMP-binding PF00501.28 PRP79129.1 - 2e-91 306.7 0.0 2.7e-91 306.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP79129.1 - 1.4e-17 64.4 1.8 2.7e-17 63.5 1.8 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SH3_9 PF14604.6 PRP79130.1 - 8.3e-16 57.6 0.1 1.7e-06 27.8 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PRP79130.1 - 8.4e-13 47.7 0.3 8.1e-08 31.8 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 PRP79130.1 - 4.9e-10 38.9 0.0 2.3e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain DUF4600 PF15372.6 PRP79130.1 - 0.0045 17.4 17.6 0.018 15.5 0.8 3.1 3 1 1 4 4 4 2 Domain of unknown function (DUF4600) SH3_3 PF08239.11 PRP79130.1 - 0.028 14.7 0.1 0.059 13.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain AKNA PF12443.8 PRP79130.1 - 2.8 8.6 9.4 0.06 14.0 1.6 2.2 3 0 0 3 3 3 0 AT-hook-containing transcription factor U79_P34 PF03064.16 PRP79130.1 - 5 6.4 11.1 0.13 11.6 4.1 1.9 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF1664 PF07889.12 PRP79130.1 - 6.6 6.8 6.7 6 6.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 PRP79130.1 - 8.4 4.2 6.6 15 3.4 6.6 1.4 1 0 0 1 1 1 0 Prominin PRC2_HTH_1 PF18118.1 PRP79130.1 - 8.9 7.2 8.0 2.4 9.0 0.2 2.8 3 1 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain PPR_2 PF13041.6 PRP79131.1 - 1.3e-28 98.9 9.4 3.6e-06 27.1 0.0 7.6 5 2 2 7 7 7 7 PPR repeat family PPR_3 PF13812.6 PRP79131.1 - 5.3e-18 64.8 0.0 4.9e-06 26.5 0.0 5.8 4 1 1 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP79131.1 - 3.3e-14 52.8 0.0 6.4e-05 22.4 0.0 3.3 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PRP79131.1 - 9.2e-11 41.2 9.6 0.013 15.7 0.0 8.6 9 0 0 9 9 9 2 PPR repeat PPR_1 PF12854.7 PRP79131.1 - 1.9e-09 37.1 0.0 0.21 11.3 0.3 5.5 5 0 0 5 5 5 2 PPR repeat ECSIT PF06239.11 PRP79131.1 - 5.6e-05 22.4 0.0 0.59 9.2 0.0 3.4 3 0 0 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway NTP_transf_6 PF06042.11 PRP79131.1 - 0.0026 17.7 0.3 0.0055 16.6 0.3 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase IPPT PF01715.17 PRP79131.1 - 0.013 15.3 0.7 0.18 11.6 0.0 2.7 2 1 0 3 3 3 0 IPP transferase DUF3826 PF12875.7 PRP79131.1 - 0.3 11.2 3.2 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) Tim44 PF04280.15 PRP79132.1 - 1.6e-07 31.5 0.0 2.7e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Tim44-like domain DUF4690 PF15756.5 PRP79132.1 - 0.00014 22.4 0.4 0.00055 20.5 0.4 2.1 1 0 0 1 1 1 1 Small Novel Rich in Cartilage SapB_2 PF03489.17 PRP79132.1 - 0.0029 17.7 0.0 0.0073 16.4 0.0 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 2 MBA1 PF07961.11 PRP79132.1 - 0.0055 15.8 0.1 0.014 14.5 0.2 1.6 2 0 0 2 2 2 1 MBA1-like protein BB_PF PF18063.1 PRP79132.1 - 0.041 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Beta barrel Pore-forming domain EB PF01683.18 PRP79132.1 - 0.48 10.7 5.1 0.15 12.4 1.3 2.1 2 0 0 2 2 2 0 EB module EGF_2 PF07974.13 PRP79132.1 - 0.73 10.3 15.8 0.38 11.1 9.9 2.6 2 0 0 2 2 2 0 EGF-like domain zf-CHY PF05495.12 PRP79134.1 - 1.4e-10 41.5 11.7 1.4e-10 41.5 11.7 4.6 3 1 1 4 4 4 1 CHY zinc finger RWD PF05773.22 PRP79134.1 - 6e-09 36.2 0.5 1.9e-08 34.6 0.1 2.1 2 0 0 2 2 2 1 RWD domain LMBR1 PF04791.16 PRP79134.1 - 1.7 7.5 2.9 2.9 6.7 2.9 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein 4HBT_2 PF13279.6 PRP79135.1 - 3.6e-13 50.1 0.5 6.4e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 PRP79135.1 - 0.061 12.6 0.5 0.13 11.5 0.4 1.5 2 0 0 2 2 2 0 Acyl-ACP thioesterase Ysc84 PF04366.12 PRP79139.1 - 0.049 13.4 0.1 0.063 13.0 0.1 1.1 1 0 0 1 1 1 0 Las17-binding protein actin regulator FSH1 PF03959.13 PRP79142.1 - 1.6e-26 93.3 0.0 1.3e-25 90.3 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Pkinase PF00069.25 PRP79144.1 - 1e-46 159.5 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79144.1 - 4.8e-16 58.8 0.0 6.4e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP79144.1 - 2e-07 30.7 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP79144.1 - 1.5e-05 24.5 0.0 7.4e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP79144.1 - 0.00014 21.5 0.1 0.00022 20.9 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PRP79144.1 - 0.0041 17.1 0.0 0.55 10.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-SAP30 PF13866.6 PRP79144.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 SAP30 zinc-finger Haspin_kinase PF12330.8 PRP79144.1 - 0.096 11.6 0.1 0.14 11.1 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Asp PF00026.23 PRP79145.1 - 1.9e-37 129.4 0.3 7.9e-37 127.3 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 PRP79145.1 - 1.8e-18 66.8 0.0 3.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 PRP79145.1 - 9.8e-14 52.0 7.6 9.8e-14 52.0 7.6 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal EamA PF00892.20 PRP79146.1 - 7.9e-08 32.6 30.6 5.4e-06 26.6 3.9 3.9 5 0 0 5 5 5 2 EamA-like transporter family PUNUT PF16913.5 PRP79146.1 - 0.71 9.0 22.5 0.028 13.7 8.3 3.5 3 1 0 3 3 3 0 Purine nucleobase transmembrane transport DUF1129 PF06570.11 PRP79147.1 - 1.5 8.2 4.3 2.5 7.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Sdh_cyt PF01127.22 PRP79147.1 - 2.3 8.3 4.9 3.2 7.8 4.9 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit VIT PF08487.10 PRP79148.1 - 3.1e-25 88.5 0.0 6.1e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VIT_2 PF13757.6 PRP79148.1 - 6.8e-09 35.5 0.0 2.2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Endosulfine PF04667.17 PRP79148.1 - 0.00073 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF924 PF06041.11 PRP79148.1 - 0.039 14.1 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) UNC-50 PF05216.13 PRP79149.1 - 1.2e-80 270.2 30.9 1.4e-80 270.0 30.9 1.0 1 0 0 1 1 1 1 UNC-50 family Prefoldin_2 PF01920.20 PRP79150.1 - 1.3e-20 73.3 3.2 1.6e-20 73.0 3.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit DegS PF05384.11 PRP79150.1 - 0.021 14.3 1.4 1.1 8.7 0.1 2.1 2 0 0 2 2 2 0 Sensor protein DegS Prefoldin PF02996.17 PRP79150.1 - 0.029 14.3 1.5 0.059 13.3 1.4 1.5 1 1 0 1 1 1 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 PRP79150.1 - 0.23 11.7 3.2 7.9 6.8 0.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CdvA PF18822.1 PRP79150.1 - 0.28 11.0 4.1 1.1 9.1 0.4 2.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Aldo_ket_red PF00248.21 PRP79151.1 - 4e-57 193.7 0.0 1.7e-56 191.6 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family MORN PF02493.20 PRP79152.1 - 1.7e-16 59.0 29.8 2.8e-05 23.7 0.2 8.1 8 1 0 8 8 8 5 MORN repeat COMM_domain PF07258.14 PRP79153.1 - 3e-15 56.1 0.2 7.8e-15 54.8 0.1 1.8 2 0 0 2 2 2 1 COMM domain LINES_N PF14694.6 PRP79154.1 - 7.5e-08 32.2 0.7 3.1e-07 30.2 0.7 2.0 1 1 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 PRP79154.1 - 3.9e-05 23.0 0.0 0.0001 21.6 0.0 1.7 1 0 0 1 1 1 1 Lines C-terminus AAA PF00004.29 PRP79156.1 - 2.1e-16 60.6 0.0 4.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP79156.1 - 0.00013 22.3 0.8 0.0012 19.1 0.0 2.8 3 1 1 4 4 3 1 AAA domain AAA_16 PF13191.6 PRP79156.1 - 0.00028 21.3 1.0 0.0016 18.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PRP79156.1 - 0.00054 20.0 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 PRP79156.1 - 0.0046 16.8 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PRP79156.1 - 0.0079 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 PRP79156.1 - 0.027 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PRP79156.1 - 0.033 14.3 0.0 0.086 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 PRP79156.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 PRP79156.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 PRP79156.1 - 0.19 12.1 0.1 0.57 10.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF2336 PF10098.9 PRP79157.1 - 0.16 11.4 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) F-box PF00646.33 PRP79160.1 - 0.00096 19.0 0.8 0.0024 17.7 0.8 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 PRP79162.1 - 3.4e-20 72.0 4.1 4e-07 30.6 0.1 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP79162.1 - 5.7e-18 65.0 0.0 0.018 15.3 0.0 4.6 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 PRP79162.1 - 6.5e-05 21.4 0.0 0.011 14.1 0.0 2.3 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 PRP79162.1 - 0.00057 18.7 0.2 0.59 8.8 0.0 2.5 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.6 PRP79162.1 - 0.0041 16.7 0.1 2.6 7.6 0.0 2.6 3 0 0 3 3 3 2 PQQ-like domain Ge1_WD40 PF16529.5 PRP79162.1 - 0.0087 15.1 0.0 0.51 9.2 0.0 3.1 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP79162.1 - 0.026 13.2 1.8 1.1 7.8 0.2 2.4 2 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 PRP79162.1 - 0.051 12.9 0.3 2.7 7.2 0.1 2.8 2 1 1 3 3 3 0 WD40-like domain DUF21 PF01595.20 PRP79163.1 - 2e-30 105.8 3.0 4.1e-30 104.8 3.0 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PRP79163.1 - 0.0001 22.6 2.6 0.068 13.6 0.0 3.8 5 0 0 5 5 5 2 CBS domain ALG3 PF05208.13 PRP79164.1 - 2.9e-143 477.6 18.4 4.2e-143 477.1 18.4 1.2 1 0 0 1 1 1 1 ALG3 protein Zn_clus PF00172.18 PRP79165.1 - 0.0089 16.1 0.9 0.018 15.1 0.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3682 PF12446.8 PRP79165.1 - 0.018 15.5 0.1 0.034 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Ribonuc_red_2_N PF08471.10 PRP79165.1 - 0.038 14.2 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase HAUS4 PF14735.6 PRP79165.1 - 0.098 12.3 0.2 0.27 10.9 0.0 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 Tocopherol_cycl PF14249.6 PRP79166.1 - 4.2e-10 39.3 0.7 5.4e-09 35.6 0.7 2.0 1 1 0 1 1 1 1 Tocopherol cyclase Ank_2 PF12796.7 PRP79167.1 - 6.6e-09 36.2 1.8 0.0042 17.6 0.1 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP79167.1 - 0.0014 18.9 5.0 4.5 8.2 0.1 5.8 6 1 1 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 PRP79167.1 - 0.013 16.1 3.6 18 6.0 0.1 3.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP79167.1 - 0.076 13.4 0.6 5.2 7.5 0.1 3.7 2 2 2 4 4 4 0 Ankyrin repeats (many copies) WD40 PF00400.32 PRP79169.1 - 0.0061 17.4 0.4 0.12 13.2 0.1 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat GIT_CC PF16559.5 PRP79169.1 - 0.056 13.3 3.3 0.51 10.2 0.1 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPIP1 PF15338.6 PRP79169.1 - 0.069 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 TMEM215 PF15746.5 PRP79169.1 - 0.75 9.2 8.7 2.5 7.5 2.1 2.7 2 0 0 2 2 2 0 TMEM215 family G6PD_C PF02781.16 PRP79170.1 - 8.1e-112 373.1 0.1 1.5e-111 372.2 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PRP79170.1 - 1.4e-59 201.7 0.6 2.2e-59 201.1 0.0 1.6 2 0 0 2 2 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Val_tRNA-synt_C PF10458.9 PRP79170.1 - 0.0015 18.8 6.1 0.0042 17.3 6.1 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm GAS PF13851.6 PRP79170.1 - 0.0059 16.0 3.3 0.013 14.9 3.3 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 PRP79170.1 - 0.0095 16.0 2.5 0.022 14.8 2.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor Cluap1 PF10234.9 PRP79170.1 - 0.01 15.2 2.7 0.018 14.5 2.7 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 CortBP2 PF09727.9 PRP79170.1 - 0.01 15.7 2.9 0.023 14.6 2.9 1.5 1 0 0 1 1 1 0 Cortactin-binding protein-2 KASH_CCD PF14662.6 PRP79170.1 - 0.016 15.0 1.9 0.033 14.0 1.9 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 PRP79170.1 - 0.022 15.0 4.5 0.055 13.7 4.5 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DHR10 PF18595.1 PRP79170.1 - 0.022 14.8 4.3 0.042 13.9 4.3 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Cnn_1N PF07989.11 PRP79170.1 - 0.027 14.6 4.1 0.074 13.2 4.1 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 SOGA PF11365.8 PRP79170.1 - 0.048 14.8 1.2 0.15 13.2 1.2 1.8 1 0 0 1 1 1 0 Protein SOGA UPF0449 PF15136.6 PRP79170.1 - 0.075 13.5 0.4 0.3 11.6 0.4 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DivIC PF04977.15 PRP79170.1 - 0.083 12.7 1.8 0.2 11.4 1.8 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF3847 PF12958.7 PRP79170.1 - 0.095 12.8 2.6 0.29 11.3 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Fusion_gly PF00523.18 PRP79170.1 - 0.21 9.8 0.1 0.3 9.3 0.1 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Tmemb_cc2 PF10267.9 PRP79170.1 - 0.38 9.8 5.1 0.23 10.6 2.8 1.7 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein PRKG1_interact PF15898.5 PRP79170.1 - 0.42 11.5 6.0 0.071 14.0 1.7 2.0 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 PRP79170.1 - 0.7 10.4 5.5 0.084 13.4 1.1 1.7 2 0 0 2 2 1 0 Apg6 coiled-coil region Phage_GPO PF05929.11 PRP79170.1 - 0.71 9.5 4.5 0.31 10.6 1.9 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HMMR_C PF15908.5 PRP79170.1 - 0.76 10.0 8.0 0.072 13.4 3.1 1.8 2 0 0 2 2 1 0 Hyaluronan mediated motility receptor C-terminal YtxH PF12732.7 PRP79170.1 - 1 9.9 6.1 3.3 8.3 0.2 2.6 2 0 0 2 2 2 0 YtxH-like protein FAM76 PF16046.5 PRP79170.1 - 1.1 8.5 7.8 0.65 9.3 5.8 1.5 2 0 0 2 2 2 0 FAM76 protein dsrm PF00035.26 PRP79171.1 - 8e-16 58.5 0.1 1.6e-09 38.3 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif WW PF00397.26 PRP79171.1 - 0.022 14.9 0.1 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 WW domain CN_hydrolase PF00795.22 PRP79172.1 - 6.5e-54 183.0 0.0 8.3e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MBOAT PF03062.19 PRP79173.1 - 2.2e-44 152.2 1.7 4.9e-44 151.1 1.7 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family ThiW PF09512.10 PRP79173.1 - 0.069 13.3 3.8 0.17 12.0 2.5 2.2 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Rhodanese_C PF12368.8 PRP79174.1 - 5.6e-10 39.4 11.5 1.3e-09 38.2 11.5 1.7 1 0 0 1 1 1 1 Rhodanase C-terminal M_domain PF12938.7 PRP79176.1 - 0.049 13.4 0.1 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 M domain of GW182 DUF3963 PF13124.6 PRP79183.1 - 0.83 9.7 2.8 1.8 8.6 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) PQ-loop PF04193.14 PRP79184.1 - 4.1e-20 71.3 9.6 6.5e-14 51.4 0.1 3.1 3 0 0 3 3 3 2 PQ loop repeat RGM_N PF06535.12 PRP79184.1 - 0.2 11.9 0.0 0.26 11.5 0.0 1.1 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) N-terminus WD40 PF00400.32 PRP79185.1 - 7.5e-25 86.7 29.7 1.7e-06 28.6 0.3 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat BTB_2 PF02214.22 PRP79185.1 - 2.3e-07 31.1 0.4 0.00016 22.0 0.4 2.6 1 1 0 1 1 1 1 BTB/POZ domain ATP-grasp PF02222.22 PRP79185.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain CALCOCO1 PF07888.11 PRP79185.1 - 0.031 13.2 9.3 0.048 12.5 9.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1921 PF09081.10 PRP79185.1 - 0.031 14.5 2.2 6.2 7.1 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1921) Read-through PF16814.5 PRP79185.1 - 0.073 12.9 1.8 8.3 6.2 0.1 3.6 1 1 3 4 4 4 0 Read-through domain DUF769 PF05590.11 PRP79185.1 - 0.4 10.1 3.4 24 4.3 0.0 3.7 2 1 3 5 5 5 0 Xylella fastidiosa protein of unknown function (DUF769) Invasin_D3 PF09134.10 PRP79185.1 - 4.3 7.7 8.6 7.4 7.0 3.0 3.7 1 1 2 3 3 3 0 Invasin, domain 3 Sel1 PF08238.12 PRP79186.1 - 2e-50 168.1 17.9 2.6e-08 34.3 0.0 6.5 6 0 0 6 6 6 6 Sel1 repeat TPR_16 PF13432.6 PRP79186.1 - 0.39 11.4 7.7 1.8 9.3 3.1 3.3 2 2 2 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 PRP79187.1 - 1e-38 133.1 0.0 1.9e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79187.1 - 1.3e-33 116.5 0.0 2.1e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_6 PF13405.6 PRP79187.1 - 0.0049 16.7 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain Pex24p PF06398.11 PRP79187.1 - 3.4 6.6 7.9 6.7 5.6 7.9 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin EMP70 PF02990.16 PRP79188.1 - 6.4e-158 526.6 14.2 8.6e-158 526.2 14.2 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 PRP79188.1 - 0.0003 19.8 10.1 0.0003 19.8 10.1 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily CBS PF00571.28 PRP79189.1 - 1.3e-20 73.6 2.2 3.9e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain Voltage_CLC PF00654.20 PRP79189.1 - 1.5e-10 40.9 1.5 1.8e-10 40.6 1.5 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel HicB-like_2 PF15970.5 PRP79189.1 - 8.7e-05 22.6 0.1 0.48 10.6 0.0 2.4 1 1 1 2 2 2 2 HicB_like antitoxin of bacterial toxin-antitoxin system DUF1725 PF08333.11 PRP79189.1 - 6 6.7 6.1 66 3.3 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1725) SET PF00856.28 PRP79190.1 - 4.6e-15 56.4 0.1 5.4e-15 56.2 0.1 1.0 1 0 0 1 1 1 1 SET domain DUF4176 PF13780.6 PRP79190.1 - 0.006 16.6 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4176) Dynactin PF12455.8 PRP79192.1 - 9.8e-31 107.0 8.5 9.8e-31 107.0 8.5 4.5 4 1 1 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 PRP79192.1 - 7.7e-22 77.1 0.1 1.3e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Glyco_transf_54 PF04666.13 PRP79192.1 - 2e-07 30.2 0.6 5.1e-05 22.3 0.1 3.2 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region PPR_2 PF13041.6 PRP79193.1 - 1.8e-33 114.5 15.2 1.6e-08 34.6 0.6 8.7 5 2 5 10 10 10 5 PPR repeat family PPR_3 PF13812.6 PRP79193.1 - 3.9e-30 103.7 8.4 4.1e-07 30.0 1.5 7.9 3 3 8 11 11 11 8 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP79193.1 - 1.5e-17 63.7 2.6 7.2e-06 25.5 0.1 3.7 2 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PRP79193.1 - 5.8e-15 54.4 23.2 0.0087 16.2 0.0 11.6 14 0 0 14 14 14 4 PPR repeat PPR_1 PF12854.7 PRP79193.1 - 8.4e-06 25.4 3.2 13 5.5 0.0 8.0 10 0 0 10 10 10 1 PPR repeat Exog_C PF18026.1 PRP79193.1 - 0.0062 16.6 0.2 31 4.7 0.0 4.7 5 0 0 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain Radical_SAM PF04055.21 PRP79193.1 - 0.023 15.1 0.3 3.4 8.0 0.0 3.1 2 1 1 3 3 3 0 Radical SAM superfamily ECSIT PF06239.11 PRP79193.1 - 0.034 13.3 4.4 0.088 11.9 0.5 3.3 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway MRP-S27 PF10037.9 PRP79193.1 - 0.039 12.8 1.0 2.5 6.9 0.1 2.9 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 BKACE PF05853.12 PRP79193.1 - 0.089 12.1 1.1 4.4 6.5 0.1 3.1 1 1 2 3 3 3 0 beta-keto acid cleavage enzyme DUF4911 PF16256.5 PRP79193.1 - 0.35 10.9 2.8 1.6 8.8 0.0 3.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4911) Clathrin PF00637.20 PRP79193.1 - 0.59 10.0 5.7 5.1 7.0 0.2 4.3 4 1 2 6 6 6 0 Region in Clathrin and VPS Abhydrolase_3 PF07859.13 PRP79195.1 - 2.9e-13 50.2 0.0 1.2e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PRP79195.1 - 7.7e-11 41.5 0.0 5.4e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 PRP79195.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family FGGY_N PF00370.21 PRP79198.1 - 9.6e-68 228.4 0.0 2.8e-67 226.8 0.0 1.8 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PRP79198.1 - 3.2e-62 209.8 0.0 5.1e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain WW PF00397.26 PRP79198.1 - 2.5 8.3 4.5 36 4.5 0.1 3.5 3 0 0 3 3 3 0 WW domain Pkinase_Tyr PF07714.17 PRP79199.1 - 8.6e-23 80.9 0.0 1.7e-19 70.1 0.0 2.5 1 1 0 2 2 2 2 Protein tyrosine kinase DNA_pol_A_exo1 PF01612.20 PRP79199.1 - 2e-20 73.2 0.0 3.9e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.25 PRP79199.1 - 6.6e-08 32.2 0.0 5.1e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GPS PF01825.21 PRP79199.1 - 6.4e-07 29.8 4.1 6.4e-07 29.8 4.1 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP79199.1 - 1e-05 25.8 13.5 9.7e-05 22.7 1.6 4.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF4428 PF14471.6 PRP79199.1 - 0.017 15.1 0.4 0.12 12.3 0.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) DUF4166 PF13761.6 PRP79199.1 - 0.15 11.8 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) LRR_8 PF13855.6 PRP79199.1 - 0.19 11.5 17.0 0.022 14.5 6.6 3.5 1 1 3 4 4 4 0 Leucine rich repeat PRIMA1 PF16101.5 PRP79199.1 - 0.22 11.6 5.0 3 7.9 2.5 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_carr PF00153.27 PRP79200.1 - 1.3e-08 34.7 0.3 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Guanylate_cyc PF00211.20 PRP79202.1 - 1.3e-32 112.9 5.4 1.9e-19 70.0 0.2 3.3 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain GGDEF PF00990.21 PRP79202.1 - 0.00025 20.9 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain GrpE PF01025.19 PRP79203.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 GrpE Pkinase_Tyr PF07714.17 PRP79204.1 - 7.5e-78 261.4 0.0 1.1e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79204.1 - 1.4e-45 155.7 0.0 2.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Chlam_PMP PF02415.17 PRP79204.1 - 0.016 15.7 42.3 0.96 10.1 0.0 12.4 12 0 0 12 12 12 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kinase-like PF14531.6 PRP79204.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RCC1_2 PF13540.6 PRP79204.1 - 0.46 10.4 3.2 0.45 10.4 0.9 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat AI-2E_transport PF01594.16 PRP79205.1 - 2.5e-17 63.1 30.9 2.5e-17 63.1 30.9 2.2 2 0 0 2 2 2 2 AI-2E family transporter TRIQK PF15168.6 PRP79205.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.8 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Glyco_hydro_16 PF00722.21 PRP79206.1 - 2.3e-14 53.3 0.4 8.7e-14 51.4 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 RasGAP PF00616.19 PRP79207.1 - 0.00029 20.6 0.0 0.00094 18.9 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase TIG PF01833.24 PRP79207.1 - 0.0084 16.2 0.3 0.0084 16.2 0.3 6.0 5 2 1 6 6 6 1 IPT/TIG domain Syndecan PF01034.20 PRP79207.1 - 0.055 13.4 2.1 0.13 12.2 2.1 1.6 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 PRP79207.1 - 0.14 13.1 0.0 0.31 11.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SapB_2 PF03489.17 PRP79208.1 - 3.6e-08 33.4 1.3 2.8e-07 30.5 0.4 2.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 TPR_1 PF00515.28 PRP79209.1 - 1.3e-13 50.1 11.5 0.024 14.4 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 PRP79209.1 - 2.6e-13 49.9 1.4 0.0019 18.3 0.0 4.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP79209.1 - 3e-13 48.8 9.2 0.16 12.2 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79209.1 - 1.7e-09 37.1 9.2 0.0087 16.2 0.0 7.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP79209.1 - 2.3e-06 28.0 9.3 0.29 11.7 0.2 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP79209.1 - 4.6e-05 23.9 3.3 10 7.2 0.0 6.1 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP79209.1 - 0.00016 21.8 0.1 14 6.4 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP79209.1 - 0.00091 19.8 2.2 11 6.8 0.0 5.5 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP79209.1 - 0.0099 16.2 10.1 1.5 9.2 0.0 5.3 5 2 1 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP79209.1 - 0.04 14.1 7.4 0.36 11.1 0.5 3.7 4 1 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PRP79209.1 - 0.11 12.3 1.2 2.7 7.8 0.0 3.7 4 1 1 5 5 5 0 TPR repeat TPR_10 PF13374.6 PRP79209.1 - 3.9 7.5 5.7 12 5.9 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 PRP79211.1 - 0.004 16.4 0.0 0.0048 16.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_9 PF13901.6 PRP79212.1 - 1.8e-42 145.7 7.7 3.1e-42 144.9 7.7 1.4 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon RUN PF02759.19 PRP79212.1 - 1.5e-13 50.9 0.0 8.6e-13 48.4 0.0 2.3 2 0 0 2 2 2 1 RUN domain DUF1213 PF06740.12 PRP79212.1 - 0.0015 19.1 7.0 8.5 7.0 0.0 5.1 4 1 1 5 5 5 2 Protein of unknown function (DUF1213) Prok-RING_1 PF14446.6 PRP79212.1 - 1.4 8.9 12.4 3.2 7.7 9.5 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_2 PF14445.6 PRP79212.1 - 1.6 8.9 7.6 0.13 12.4 1.9 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Fe-S_biosyn PF01521.20 PRP79213.1 - 1.3e-14 54.3 0.0 1.7e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF61 PF01886.16 PRP79213.1 - 0.05 13.6 0.1 0.099 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF61 UPF0547 PF10571.9 PRP79213.1 - 0.61 10.2 0.2 0.61 10.2 0.2 2.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Abhydro_lipase PF04083.16 PRP79214.1 - 7e-16 57.6 0.0 1.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 PRP79214.1 - 2.4e-09 37.2 0.7 5.9e-08 32.7 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP79214.1 - 0.00038 19.8 0.1 0.0091 15.3 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Esterase PF00756.20 PRP79214.1 - 0.051 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Putative esterase YccV-like PF08755.11 PRP79215.1 - 2.2e-21 76.2 1.4 7e-21 74.6 1.4 1.9 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 PRP79215.1 - 2.2e-16 59.8 0.0 3.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 PRP79215.1 - 4e-08 33.0 0.4 1e-07 31.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP79215.1 - 5.6e-07 29.3 0.1 1.1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain DMRL_synthase PF00885.19 PRP79217.1 - 2.5e-58 195.9 0.0 3.2e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Rubis-subs-bind PF09273.11 PRP79218.1 - 4.8e-20 72.6 0.1 9.2e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Aldo_ket_red PF00248.21 PRP79219.1 - 3.2e-47 161.2 0.0 2e-44 151.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.12 PRP79220.1 - 4.4e-42 144.0 0.0 7e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 PRP79220.1 - 1.4e-24 86.5 0.1 4.1e-24 84.9 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 PRP79220.1 - 2.2e-09 37.1 0.0 5.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 PRP79220.1 - 2.5e-08 34.1 0.0 4.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 PRP79220.1 - 4.8e-05 23.3 0.1 0.00014 21.9 0.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PRP79220.1 - 0.067 12.3 0.0 0.77 8.8 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PRP79220.1 - 0.079 12.0 0.0 5.7 5.9 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Nop53 PF07767.11 PRP79222.1 - 5.8e-13 49.0 7.4 5.8e-13 49.0 7.4 3.4 1 1 1 3 3 3 1 Nop53 (60S ribosomal biogenesis) GREB1 PF15782.5 PRP79222.1 - 1.5 5.8 15.0 2.1 5.4 15.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4874 PF16173.5 PRP79223.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) DUF4832 PF16116.5 PRP79223.1 - 0.015 15.2 0.0 0.055 13.3 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4832) WD40 PF00400.32 PRP79224.1 - 7.8e-25 86.7 16.8 3.2e-05 24.6 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat F-box-like PF12937.7 PRP79224.1 - 1.2e-11 44.3 0.2 3.1e-11 43.0 0.0 1.8 2 0 0 2 2 1 1 F-box-like ANAPC4_WD40 PF12894.7 PRP79224.1 - 5e-06 26.7 1.4 0.041 14.2 0.1 3.9 2 1 2 4 4 3 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 PRP79224.1 - 1.3e-05 24.9 1.2 2.7e-05 23.9 0.4 2.0 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 PRP79224.1 - 3.4e-05 23.3 0.3 7.9e-05 22.1 0.3 1.5 1 0 0 1 1 1 1 WD40-like domain F-box_5 PF18511.1 PRP79224.1 - 0.00062 19.3 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 F-box zf-C3HC4_3 PF13920.6 PRP79224.1 - 0.0047 16.8 12.9 0.012 15.5 12.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP79224.1 - 0.035 14.0 12.6 0.089 12.7 12.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PQQ PF01011.21 PRP79224.1 - 0.1 12.6 1.4 26 5.0 0.0 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat zf-RING_UBOX PF13445.6 PRP79224.1 - 0.72 9.9 11.2 5.3 7.2 8.2 3.0 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 PRP79224.1 - 0.91 9.5 13.5 3.8 7.5 13.4 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Rhodanese_C PF12368.8 PRP79224.1 - 1.4 9.3 8.7 11 6.5 6.5 2.6 2 0 0 2 2 2 0 Rhodanase C-terminal zf-C3HC4 PF00097.25 PRP79224.1 - 4.1 7.4 11.7 43 4.1 12.3 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 PRP79224.1 - 9.8 6.3 11.3 21 5.3 11.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon CIMR PF00878.18 PRP79225.1 - 7.1e-05 22.9 0.0 0.00024 21.2 0.0 1.8 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat TPR_1 PF00515.28 PRP79226.1 - 3.6e-14 51.9 0.1 2.3e-07 30.4 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP79226.1 - 5.7e-13 47.9 0.4 1.6e-05 24.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79226.1 - 9.3e-10 37.9 1.0 0.0037 17.4 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP79226.1 - 3e-08 33.2 0.2 3.9e-05 23.2 0.0 3.8 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 PRP79226.1 - 1.8e-06 28.4 0.0 4.7e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP79226.1 - 2.9e-06 27.3 0.1 6e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP79226.1 - 3.2e-05 23.6 0.2 0.0017 18.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP79226.1 - 9.5e-05 22.6 0.1 0.00033 20.9 0.1 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP79226.1 - 0.00032 21.3 0.4 0.24 12.3 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP79226.1 - 0.0021 18.5 0.9 0.0061 17.1 0.6 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 PRP79226.1 - 0.0035 17.6 0.2 0.96 10.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP79226.1 - 0.0051 17.4 1.6 8.2 7.3 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP79226.1 - 0.0072 16.2 0.6 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 PRP79226.1 - 0.009 15.0 1.3 0.014 14.3 1.3 1.2 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 PRP79226.1 - 0.11 11.7 0.7 0.41 9.8 0.6 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat CstA_5TM PF13722.6 PRP79227.1 - 0.098 13.0 0.0 2.3 8.6 0.0 2.2 2 0 0 2 2 2 0 5TM C-terminal transporter carbon starvation CstA zf-HC5HC2H_2 PF13832.6 PRP79228.1 - 1.3e-30 105.8 6.7 1.3e-30 105.8 6.7 4.7 4 1 1 5 5 5 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PRP79228.1 - 2.2e-23 82.3 5.0 2.2e-23 82.3 5.0 6.4 5 2 2 7 7 7 2 PHD-like zinc-binding domain EPL1 PF10513.9 PRP79228.1 - 1.5e-18 67.7 1.4 1.5e-18 67.7 1.4 6.1 4 1 0 4 4 4 1 Enhancer of polycomb-like Bromodomain PF00439.25 PRP79228.1 - 1.1e-16 60.6 0.0 1.1e-16 60.6 0.0 2.4 3 0 0 3 3 3 1 Bromodomain PHD PF00628.29 PRP79228.1 - 2.8e-07 30.3 72.6 0.0027 17.6 7.9 6.4 5 1 0 5 5 5 4 PHD-finger PHD_2 PF13831.6 PRP79228.1 - 0.00021 20.8 6.2 0.006 16.1 0.1 5.9 5 0 0 5 5 5 3 PHD-finger Zn_clus PF00172.18 PRP79228.1 - 0.00093 19.3 7.3 0.00093 19.3 7.3 5.9 6 1 0 6 6 6 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 PRP79229.1 - 5.7e-57 191.8 0.2 6.6e-57 191.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79229.1 - 3.6e-35 120.8 0.0 6.1e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP79229.1 - 1.7e-17 63.4 0.2 2.1e-17 63.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP79229.1 - 2e-05 24.2 0.2 8.1e-05 22.3 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP79229.1 - 4.7e-05 23.4 0.0 0.00026 21.0 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP79229.1 - 0.0014 18.5 0.8 0.082 12.8 0.0 2.3 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 PRP79229.1 - 0.0025 17.3 0.8 0.027 13.9 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PRP79229.1 - 0.0029 17.0 0.1 0.0039 16.6 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 PRP79229.1 - 0.027 14.2 0.4 0.08 12.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain Septin PF00735.18 PRP79229.1 - 0.028 13.7 0.1 0.061 12.6 0.0 1.5 2 0 0 2 2 2 0 Septin TniB PF05621.11 PRP79229.1 - 0.029 13.8 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 PRP79229.1 - 0.034 14.5 0.1 0.45 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 PRP79229.1 - 0.049 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 PRP79229.1 - 0.061 12.8 0.0 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 PRP79229.1 - 0.067 12.3 1.3 0.56 9.3 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 PRP79229.1 - 0.12 12.7 0.0 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PRP79229.1 - 0.19 12.2 0.7 0.87 10.1 0.7 2.0 1 1 0 1 1 1 0 ABC transporter AAA_6 PF12774.7 PRP79236.1 - 1.7e-136 454.5 0.1 6.7e-136 452.6 0.0 2.2 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PRP79236.1 - 2.8e-120 402.1 9.8 2.8e-120 402.1 9.8 6.1 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 PRP79236.1 - 2.5e-116 389.6 14.7 2.5e-116 389.6 14.7 4.1 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 PRP79236.1 - 3.3e-71 238.9 0.0 3.3e-71 238.9 0.0 4.1 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 PRP79236.1 - 1.6e-70 237.4 0.0 7.1e-70 235.3 0.0 2.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PRP79236.1 - 5e-51 173.8 0.1 2.3e-50 171.6 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 PRP79236.1 - 5.4e-42 143.4 0.0 5e-36 123.9 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PRP79236.1 - 2.2e-38 131.7 0.0 7.1e-38 130.0 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PRP79236.1 - 2e-37 129.0 6.5 4.5e-37 127.9 6.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 PRP79236.1 - 1.2e-32 112.8 0.0 1.3e-14 54.4 0.0 6.2 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 PRP79236.1 - 1.6e-29 102.4 0.0 1.1e-28 99.7 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PRP79236.1 - 5.4e-18 65.3 0.0 2.1e-17 63.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 PRP79236.1 - 8.4e-13 48.8 0.0 0.063 13.6 0.0 6.3 5 0 0 5 5 5 4 AAA domain AAA PF00004.29 PRP79236.1 - 1.8e-12 47.8 0.0 0.031 14.7 0.0 5.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PRP79236.1 - 2.3e-08 34.3 0.2 0.025 14.8 0.0 5.3 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.6 PRP79236.1 - 3.9e-08 33.9 1.1 1.3 9.4 0.0 7.3 7 0 0 7 7 6 1 AAA ATPase domain AAA_lid_1 PF17857.1 PRP79236.1 - 5.5e-08 33.0 0.4 4.6e-06 26.8 0.0 3.3 2 0 0 2 2 2 1 AAA+ lid domain RNA_helicase PF00910.22 PRP79236.1 - 0.00056 20.3 0.0 13 6.3 0.0 5.4 5 0 0 5 5 5 0 RNA helicase T2SSE PF00437.20 PRP79236.1 - 0.0007 18.7 0.0 0.05 12.7 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein ADIP PF11559.8 PRP79236.1 - 0.0013 18.8 28.0 0.15 12.2 0.3 4.6 4 0 0 4 4 3 2 Afadin- and alpha -actinin-Binding Mg_chelatase PF01078.21 PRP79236.1 - 0.0024 17.3 4.1 1.3 8.3 0.0 3.7 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 PRP79236.1 - 0.0033 18.0 12.9 7.2 7.2 0.0 6.9 7 0 0 7 7 4 0 AAA domain GreA_GreB_N PF03449.15 PRP79236.1 - 0.0039 17.3 1.1 0.2 11.8 0.0 4.0 3 0 0 3 3 2 1 Transcription elongation factor, N-terminal AAA_29 PF13555.6 PRP79236.1 - 0.0047 16.6 0.0 5 6.9 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 PRP79236.1 - 0.0054 16.5 0.4 36 4.0 0.4 3.9 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 PRP79236.1 - 0.0083 16.5 3.1 0.77 10.1 0.0 4.8 6 0 0 6 6 5 1 AAA domain IstB_IS21 PF01695.17 PRP79236.1 - 0.0084 15.9 0.4 1.4 8.6 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_25 PF13481.6 PRP79236.1 - 0.0085 15.7 2.0 0.055 13.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 PRP79236.1 - 0.032 14.7 5.4 4.4 7.8 0.0 5.5 5 0 0 5 5 3 0 ABC transporter Tropomyosin PF00261.20 PRP79236.1 - 0.17 11.3 27.0 0.033 13.6 2.2 3.5 2 0 0 2 2 2 0 Tropomyosin UPF0147 PF03685.13 PRP79236.1 - 0.24 11.5 4.5 9.2 6.4 1.9 3.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) LPP PF04728.13 PRP79236.1 - 5.2 7.5 8.8 38 4.8 0.2 5.2 3 1 1 4 4 4 0 Lipoprotein leucine-zipper LON_substr_bdg PF02190.16 PRP79237.1 - 3.7e-12 46.6 0.1 6.6e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Acetyltransf_10 PF13673.7 PRP79237.1 - 2.5e-08 33.9 0.0 5.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP79237.1 - 1e-07 32.2 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP79237.1 - 2.2e-05 24.8 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP79237.1 - 0.069 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HA2 PF04408.23 PRP79238.1 - 0.017 15.4 0.1 0.036 14.4 0.1 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) Herpes_DNAp_acc PF04929.12 PRP79238.1 - 1.1 8.1 7.9 1.5 7.7 7.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ndc1_Nup PF09531.10 PRP79238.1 - 1.4 7.5 6.6 1.9 7.0 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pet100 PF09803.9 PRP79238.1 - 7.2 7.2 6.1 8.9 6.9 4.9 1.7 1 1 0 1 1 1 0 Pet100 U1snRNP70_N PF12220.8 PRP79238.1 - 8.6 7.1 16.8 19 6.0 7.1 2.8 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DIL PF01843.19 PRP79239.1 - 5.9e-15 55.4 1.2 5.9e-15 55.4 1.2 2.6 3 0 0 3 3 1 1 DIL domain NT-C2 PF10358.9 PRP79239.1 - 2.6e-09 37.0 2.2 6.5e-09 35.6 2.2 1.7 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Spc7 PF08317.11 PRP79239.1 - 6.8e-05 21.9 19.3 0.00016 20.7 19.3 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein GAS PF13851.6 PRP79239.1 - 0.00027 20.4 19.8 0.00027 20.4 19.8 1.8 2 0 0 2 2 1 1 Growth-arrest specific micro-tubule binding FPP PF05911.11 PRP79239.1 - 0.00042 18.7 15.2 0.00042 18.7 15.2 1.5 2 0 0 2 2 1 1 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 PRP79239.1 - 0.0013 19.3 31.0 0.0023 18.5 12.7 2.9 1 1 1 2 2 2 1 Apg6 coiled-coil region HOOK PF05622.12 PRP79239.1 - 0.002 16.4 19.7 0.0033 15.7 19.7 1.2 1 0 0 1 1 1 1 HOOK protein TMF_DNA_bd PF12329.8 PRP79239.1 - 0.0028 17.6 10.9 0.0028 17.6 10.9 3.3 3 0 0 3 3 2 1 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.8 PRP79239.1 - 0.0047 14.5 16.3 0.0075 13.9 16.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4795 PF16043.5 PRP79239.1 - 0.0048 16.5 14.4 0.017 14.8 14.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) DUF4164 PF13747.6 PRP79239.1 - 0.0061 16.8 13.9 0.019 15.2 1.3 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) Filament PF00038.21 PRP79239.1 - 0.0063 16.1 12.6 0.015 14.9 12.6 1.6 1 0 0 1 1 1 1 Intermediate filament protein ATG16 PF08614.11 PRP79239.1 - 0.0066 16.7 11.0 0.0066 16.7 11.0 2.6 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) SOGA PF11365.8 PRP79239.1 - 0.0088 17.2 14.4 0.068 14.3 1.1 4.1 4 0 0 4 4 3 1 Protein SOGA HAUS-augmin3 PF14932.6 PRP79239.1 - 0.0096 15.5 20.4 0.021 14.4 5.9 2.6 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 LRRFIP PF09738.9 PRP79239.1 - 0.012 15.1 17.1 0.023 14.2 17.1 1.4 1 0 0 1 1 1 0 LRRFIP family FlaC_arch PF05377.11 PRP79239.1 - 0.013 15.9 12.8 0.69 10.3 1.3 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) T3SSipB PF16535.5 PRP79239.1 - 0.021 15.3 9.5 0.051 14.1 9.5 1.7 1 0 0 1 1 1 0 Type III cell invasion protein SipB Fez1 PF06818.15 PRP79239.1 - 0.022 15.2 15.3 0.062 13.7 15.3 1.7 1 0 0 1 1 1 0 Fez1 DHR10 PF18595.1 PRP79239.1 - 0.037 14.1 19.9 0.14 12.2 7.0 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain FapA PF03961.13 PRP79239.1 - 0.07 11.7 10.8 0.16 10.6 10.8 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A ERM PF00769.19 PRP79239.1 - 0.081 12.7 21.6 0.032 14.1 18.7 1.8 2 0 0 2 2 1 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.5 PRP79239.1 - 0.088 12.9 17.2 0.45 10.6 2.3 3.6 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF4407 PF14362.6 PRP79239.1 - 0.094 12.1 14.7 0.18 11.1 14.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 PRP79239.1 - 0.12 11.3 24.7 0.36 9.7 24.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) MscS_porin PF12795.7 PRP79239.1 - 0.14 11.7 27.6 0.45 10.0 27.6 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4200 PF13863.6 PRP79239.1 - 0.17 12.3 18.0 0.12 12.7 4.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) GTP-bdg_M PF16360.5 PRP79239.1 - 0.19 12.4 6.7 0.17 12.5 4.4 2.2 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region BRE1 PF08647.11 PRP79239.1 - 0.27 11.3 17.0 0.061 13.4 4.6 3.0 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2381 PF09544.10 PRP79239.1 - 0.29 10.6 10.3 0.11 12.0 1.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2381) DUF1664 PF07889.12 PRP79239.1 - 0.32 11.0 8.6 2.7 8.1 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 PRP79239.1 - 0.41 11.1 23.2 0.23 11.9 7.0 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Golgin_A5 PF09787.9 PRP79239.1 - 0.42 10.0 16.3 0.82 9.1 16.3 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Prefoldin PF02996.17 PRP79239.1 - 0.97 9.4 16.5 2.3 8.2 4.3 3.3 3 0 0 3 3 3 0 Prefoldin subunit Sec2p PF06428.11 PRP79239.1 - 1 9.3 25.7 0.058 13.4 6.0 3.9 3 1 0 3 3 3 0 GDP/GTP exchange factor Sec2p Phage_HK97_TLTM PF06120.11 PRP79239.1 - 1.1 8.3 14.0 3.4 6.8 14.0 1.8 1 0 0 1 1 1 0 Tail length tape measure protein DUF5082 PF16888.5 PRP79239.1 - 1.2 9.5 16.3 4.3 7.6 16.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Uds1 PF15456.6 PRP79239.1 - 1.2 9.3 15.4 3.5 7.8 15.4 1.8 1 0 0 1 1 1 0 Up-regulated During Septation Prefoldin_2 PF01920.20 PRP79239.1 - 1.3 9.0 20.1 4.3 7.3 6.3 2.9 2 0 0 2 2 2 0 Prefoldin subunit MutS_IV PF05190.18 PRP79239.1 - 1.4 9.3 8.8 2.3 8.6 0.5 3.1 2 0 0 2 2 2 0 MutS family domain IV T2SSM PF04612.12 PRP79239.1 - 1.4 9.0 10.3 1.5 8.8 1.8 3.1 2 1 0 3 3 3 0 Type II secretion system (T2SS), protein M CENP-F_leu_zip PF10473.9 PRP79239.1 - 1.4 8.9 30.5 2.2 8.3 25.6 3.0 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.16 PRP79239.1 - 1.5 9.0 18.3 0.17 12.1 10.2 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein THOC7 PF05615.13 PRP79239.1 - 2.1 8.6 22.3 0.83 9.9 7.7 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 Laminin_II PF06009.12 PRP79239.1 - 2.4 8.2 12.9 5.5 7.0 3.6 2.6 1 1 0 2 2 2 0 Laminin Domain II Spc24 PF08286.11 PRP79239.1 - 2.6 8.3 23.1 1.3 9.2 6.3 3.4 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 ABC_tran_CTD PF16326.5 PRP79239.1 - 3.3 8.0 23.1 9 6.6 10.7 3.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain COG2 PF06148.11 PRP79239.1 - 3.3 7.8 15.2 8.1 6.5 3.6 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4349 PF14257.6 PRP79239.1 - 3.4 7.1 14.4 0.41 10.1 4.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) ZapB PF06005.12 PRP79239.1 - 3.4 8.2 27.8 1.1e+02 3.4 19.8 3.5 1 1 1 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 PRP79239.1 - 3.6 6.8 22.5 0.37 10.1 7.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PRKG1_interact PF15898.5 PRP79239.1 - 3.9 8.4 20.0 8.2 7.4 8.2 3.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain RPW8 PF05659.11 PRP79239.1 - 4 7.1 7.6 4.2 7.1 0.8 3.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 KELK PF15796.5 PRP79239.1 - 4.2 7.9 19.2 4.2 7.9 6.0 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1515 PF07439.11 PRP79239.1 - 4.4 7.4 6.9 2.3 8.3 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DASH_Spc19 PF08287.11 PRP79239.1 - 4.5 7.2 23.4 0.21 11.5 15.7 2.6 1 1 1 2 2 2 0 Spc19 YscO PF07321.12 PRP79239.1 - 5.2 7.0 19.5 1.9 8.4 6.9 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO Seryl_tRNA_N PF02403.22 PRP79239.1 - 5.5 7.3 19.1 15 5.9 5.8 2.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2968 PF11180.8 PRP79239.1 - 6.3 6.4 15.2 0.86 9.2 4.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) SlyX PF04102.12 PRP79239.1 - 6.6 7.4 19.9 4.5 8.0 4.5 4.0 3 0 0 3 3 3 0 SlyX KfrA_N PF11740.8 PRP79239.1 - 6.7 7.4 16.0 0.58 10.8 4.8 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DivIC PF04977.15 PRP79239.1 - 7 6.5 26.0 3 7.7 2.2 3.5 2 1 1 3 3 3 0 Septum formation initiator HR1 PF02185.16 PRP79239.1 - 8.1 6.6 18.4 0.25 11.5 6.5 2.9 2 0 0 2 2 2 0 Hr1 repeat BST2 PF16716.5 PRP79239.1 - 8.6 7.0 16.7 3.5 8.3 3.8 3.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 PRP79239.1 - 8.6 7.0 24.5 5.7 7.6 8.3 3.0 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 PRP79239.1 - 9.8 6.4 11.9 15 5.7 9.2 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family WXG100 PF06013.12 PRP79239.1 - 9.8 6.5 9.3 15 5.9 1.8 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG 2OG-FeII_Oxy_3 PF13640.6 PRP79240.1 - 1.4e-07 32.3 0.0 5.3e-07 30.4 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Rad50_zn_hook PF04423.14 PRP79241.1 - 0.16 11.9 0.2 0.16 11.9 0.2 4.4 6 1 1 7 7 7 0 Rad50 zinc hook motif DUF1644 PF07800.12 PRP79241.1 - 8.4 6.4 13.5 0.099 12.7 3.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) MFS_1 PF07690.16 PRP79243.1 - 9.1e-22 77.4 35.1 3.1e-21 75.7 35.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily JAB PF01398.21 PRP79244.1 - 1.1e-32 112.5 0.0 2.1e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 PRP79244.1 - 1.5e-12 47.9 1.0 2.9e-12 47.0 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 PRP79244.1 - 5.8e-07 29.3 0.0 9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 PRP79244.1 - 0.0029 17.7 0.2 0.0051 16.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) GED PF02212.18 PRP79244.1 - 0.51 10.5 4.7 1.6 8.9 2.5 2.6 1 1 1 2 2 2 0 Dynamin GTPase effector domain Cgr1 PF03879.14 PRP79245.1 - 3.4e-07 30.6 17.2 3.4e-07 30.6 17.2 1.5 1 1 0 1 1 1 1 Cgr1 family zf-LYAR PF08790.11 PRP79246.1 - 7.5e-14 51.3 8.0 2.7e-12 46.4 3.8 2.6 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger CDC45 PF02724.14 PRP79246.1 - 0.79 7.9 13.4 0.87 7.8 13.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 PRP79246.1 - 1.5 8.0 7.4 1.6 7.9 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 PRP79246.1 - 5.3 7.0 7.8 7.2 6.6 7.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sec23_BS PF08033.12 PRP79247.1 - 5.1e-10 39.9 0.0 9.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 PRP79247.1 - 5.3e-08 32.7 0.0 8.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 PRP79247.1 - 5.5e-08 32.7 0.9 1.1e-07 31.8 0.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 PRP79247.1 - 1e-05 25.3 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-RanBP PF00641.18 PRP79247.1 - 0.64 9.4 2.5 2.6 7.4 0.8 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 PRP79247.1 - 2.4 7.6 4.6 4.7 6.7 0.0 2.9 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SRP14 PF02290.15 PRP79248.1 - 1.4e-22 79.8 0.2 2e-22 79.3 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle 14kD protein tRNA-synt_2b PF00587.25 PRP79249.1 - 7.6e-38 130.3 0.0 1.3e-37 129.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PRP79249.1 - 2.8e-21 75.5 0.4 5.8e-21 74.4 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 PRP79249.1 - 4.3e-10 39.5 0.0 1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 PRP79249.1 - 8.9e-07 28.9 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain EamA PF00892.20 PRP79251.1 - 2.6e-07 30.9 34.9 4.4e-06 26.9 15.6 2.8 2 1 1 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 PRP79251.1 - 1.2e-06 28.3 18.6 2.4e-06 27.3 18.4 1.6 1 1 1 2 2 2 1 Solute carrier family 35 TPR_2 PF07719.17 PRP79252.1 - 7e-36 119.4 15.0 1.9e-06 27.5 0.2 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 PRP79252.1 - 1.2e-33 113.5 19.7 2.5e-06 27.1 0.2 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79252.1 - 6.2e-26 88.4 16.5 8.7e-05 22.4 0.1 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 PRP79252.1 - 2.2e-24 84.9 19.8 0.0001 21.9 0.1 8.6 5 3 3 8 8 8 8 TPR repeat TPR_16 PF13432.6 PRP79252.1 - 3.5e-24 85.2 0.1 1e-05 26.1 0.0 6.3 5 1 1 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.31 PRP79252.1 - 1e-22 80.0 3.6 1e-22 80.0 3.6 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_14 PF13428.6 PRP79252.1 - 5.1e-21 73.6 3.3 0.0034 18.1 0.1 8.1 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 PRP79252.1 - 2.7e-19 69.4 12.4 0.0019 18.7 0.9 6.3 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 PRP79252.1 - 2.8e-19 69.0 0.1 0.00025 21.1 0.1 5.3 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 PRP79252.1 - 2e-17 62.2 10.8 0.0013 18.9 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 PRP79252.1 - 4.5e-14 52.1 11.0 0.0014 19.1 0.1 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP79252.1 - 9.2e-12 45.0 11.6 0.00019 21.6 0.1 5.4 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PRP79252.1 - 9.7e-11 41.8 13.1 0.032 14.5 0.4 6.3 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_15 PF13429.6 PRP79252.1 - 1.8e-09 37.2 4.2 0.019 14.2 0.1 4.2 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 PRP79252.1 - 3.9e-07 30.0 9.9 0.055 13.2 0.5 4.4 3 2 1 4 4 4 3 Tetratricopeptide repeat-like domain RPN7 PF10602.9 PRP79252.1 - 3.4e-06 26.9 2.8 0.0042 16.8 0.1 4.2 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_7 PF13176.6 PRP79252.1 - 5.6e-06 26.0 8.6 0.7 10.1 0.0 6.6 7 1 0 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.8 PRP79252.1 - 8.2e-06 25.0 16.2 0.019 13.9 1.6 3.9 2 2 0 3 3 3 2 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 PRP79252.1 - 0.0066 16.9 7.8 11 6.5 0.0 4.2 2 1 2 4 4 4 0 Alkyl sulfatase dimerisation BTAD PF03704.17 PRP79252.1 - 0.0099 16.3 2.3 21 5.5 0.3 4.3 3 2 0 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 PRP79252.1 - 0.041 14.2 11.6 1.5 9.2 0.1 5.0 3 2 1 5 5 5 0 Tetratricopeptide repeat TOM20_plant PF06552.12 PRP79252.1 - 0.83 9.4 7.7 4.2 7.1 0.6 3.8 3 1 1 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 RPT PF13446.6 PRP79252.1 - 0.89 9.5 3.2 3.4 7.7 0.0 3.6 6 0 0 6 6 5 0 A repeated domain in UCH-protein Fis1_TPR_C PF14853.6 PRP79252.1 - 2.7 8.1 19.8 18 5.5 2.1 6.0 7 1 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat 4HB_MCP_1 PF12729.7 PRP79252.1 - 2.8 7.4 8.3 0.44 10.1 1.1 2.8 2 1 1 3 3 3 0 Four helix bundle sensory module for signal transduction MIT PF04212.18 PRP79252.1 - 3 8.0 14.6 11 6.2 1.7 5.3 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain Acyl-CoA_dh_1 PF00441.24 PRP79253.1 - 6.4e-31 107.6 0.3 1.3e-30 106.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PRP79253.1 - 2.7e-19 69.2 0.0 4.9e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PRP79253.1 - 5.1e-12 46.2 0.0 1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PRP79253.1 - 7.1e-11 42.8 0.0 1.8e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Pkinase_Tyr PF07714.17 PRP79254.1 - 9.5e-18 64.4 0.0 1.4e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79254.1 - 4.4e-16 59.0 0.0 6.9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Adeno_E1B_55K PF01696.17 PRP79254.1 - 0.36 9.5 4.6 0.22 10.2 0.0 2.9 5 0 0 5 5 5 0 Adenovirus EB1 55K protein / large t-antigen Pkinase_Tyr PF07714.17 PRP79255.1 - 8.1e-28 97.4 0.0 9.6e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79255.1 - 2.1e-13 50.2 0.0 2.3e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain AKNA PF12443.8 PRP79256.1 - 1.2 9.8 8.1 0.075 13.7 1.2 2.1 2 0 0 2 2 2 0 AT-hook-containing transcription factor Sugar_tr PF00083.24 PRP79259.1 - 1.9e-119 399.5 32.1 2.1e-119 399.3 32.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP79259.1 - 7.4e-29 100.8 56.1 8.1e-25 87.5 33.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PRP79259.1 - 0.00044 18.7 1.5 0.00044 18.7 1.5 2.2 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Tetraspanin PF00335.20 PRP79259.1 - 0.11 12.2 5.9 2.2 7.9 1.4 2.8 2 2 0 2 2 2 0 Tetraspanin family WTF PF03303.13 PRP79259.1 - 0.18 11.5 1.2 0.58 9.8 1.2 1.8 1 0 0 1 1 1 0 WTF protein Glyco_hydro_38N PF01074.22 PRP79260.1 - 1.9e-85 286.7 9.4 3.2e-85 286.0 9.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP79260.1 - 1.7e-20 74.0 1.3 2e-20 73.8 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP79260.1 - 1.7e-16 60.1 0.6 5.2e-16 58.6 0.6 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 PRP79260.1 - 0.00067 18.9 2.1 0.0013 18.0 0.8 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Glyco_hydro38C2 PF17677.1 PRP79260.1 - 0.14 12.3 1.9 0.7 10.0 1.0 2.7 2 1 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Colipase-like PF15083.6 PRP79261.1 - 0.0039 17.3 9.5 0.0077 16.3 9.5 1.4 1 0 0 1 1 1 1 Colipase-like tRNA_anti-codon PF01336.25 PRP79262.1 - 3.3e-06 27.0 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Phage_BR0599 PF09356.10 PRP79262.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Phage conserved hypothetical protein BR0599 F-box PF00646.33 PRP79263.1 - 2.4e-08 33.7 0.0 5.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP79263.1 - 4.3e-07 29.7 0.7 4.3e-07 29.7 0.7 2.2 2 0 0 2 2 2 1 F-box-like Elongin_A PF06881.11 PRP79263.1 - 0.013 16.0 0.4 0.027 15.0 0.4 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RasGEF PF00617.19 PRP79264.1 - 6.2e-33 114.5 0.2 1.3e-32 113.4 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP79264.1 - 4.3e-08 33.3 0.2 4.9e-07 29.9 0.1 2.7 3 0 0 3 3 3 1 RasGEF N-terminal motif LisH_TPL PF17814.1 PRP79264.1 - 0.0016 18.1 0.0 0.0053 16.4 0.0 1.9 1 0 0 1 1 1 1 LisH-like dimerisation domain TRAPP PF04051.16 PRP79265.1 - 2.9e-39 134.1 0.0 3.5e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF111 PF01969.17 PRP79265.1 - 0.079 12.0 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF111 Sybindin PF04099.12 PRP79266.1 - 3.9e-42 143.6 0.1 4.5e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 PRP79266.1 - 9.7e-06 25.7 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Halogen_Hydrol PF10112.9 PRP79268.1 - 0.57 10.2 0.0 0.57 10.2 0.0 2.9 3 1 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein K1 PF02960.14 PRP79269.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 K1 glycoprotein Pkinase PF00069.25 PRP79270.1 - 9.4e-27 94.0 0.0 1.9e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79270.1 - 4e-16 59.1 0.0 6.4e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP79270.1 - 1.1e-12 47.5 0.1 1.1e-12 47.5 0.1 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP79270.1 - 0.0047 16.3 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 PRP79270.1 - 0.0069 15.4 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase F-box_4 PF15966.5 PRP79270.1 - 0.013 15.4 0.2 0.025 14.4 0.2 1.5 1 0 0 1 1 1 0 F-box APH PF01636.23 PRP79270.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP79270.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like F-box PF00646.33 PRP79270.1 - 0.2 11.6 1.2 0.57 10.1 1.3 1.7 2 0 0 2 2 1 0 F-box domain RNA_polI_A34 PF08208.11 PRP79270.1 - 0.28 11.3 27.7 0.8 9.8 26.8 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 F-box-like PF12937.7 PRP79270.1 - 0.34 10.8 1.3 0.57 10.1 1.3 1.4 1 0 0 1 1 1 0 F-box-like PBP_sp32 PF07222.12 PRP79270.1 - 1.7 8.0 10.4 3.5 7.0 10.4 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Connexin PF00029.19 PRP79270.1 - 3.7 7.2 4.5 7.2 6.3 4.5 1.6 1 0 0 1 1 1 0 Connexin Nuc_sug_transp PF04142.15 PRP79271.1 - 1.7e-106 356.0 18.8 2.2e-106 355.6 18.8 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter FKBP_C PF00254.28 PRP79271.1 - 4.2e-31 107.1 0.0 1.4e-30 105.4 0.0 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 PRP79271.1 - 1.1e-13 50.4 4.5 8.5e-06 25.4 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP79271.1 - 1.2e-12 46.9 4.6 4e-06 26.5 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79271.1 - 4.9e-08 32.6 10.2 0.00055 19.9 0.1 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat EamA PF00892.20 PRP79271.1 - 1.4e-06 28.5 26.6 2e-05 24.8 1.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPR_11 PF13414.6 PRP79271.1 - 2.4e-05 23.9 0.2 0.37 10.5 0.1 3.6 2 1 1 3 3 3 2 TPR repeat UAA PF08449.11 PRP79271.1 - 4.8e-05 22.7 17.9 0.00039 19.7 17.9 2.2 1 1 0 1 1 1 1 UAA transporter family TPR_19 PF14559.6 PRP79271.1 - 8.7e-05 23.0 1.4 0.1 13.1 0.1 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP79271.1 - 0.00029 21.4 0.1 0.63 10.7 0.0 2.9 1 1 0 2 2 2 1 Tetratricopeptide repeat PUNUT PF16913.5 PRP79271.1 - 0.0011 18.3 18.3 0.0017 17.7 18.3 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport MIT PF04212.18 PRP79271.1 - 0.0029 17.6 1.3 0.13 12.3 0.0 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 PRP79271.1 - 0.0033 17.7 1.5 26 5.2 0.1 3.7 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PRP79271.1 - 0.0071 16.9 1.2 0.43 11.3 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PRP79271.1 - 0.012 15.9 0.6 1.7 9.2 0.2 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP79271.1 - 0.019 15.7 0.0 4.9 8.2 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP79271.1 - 0.024 14.7 1.0 0.7 10.0 0.1 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 PRP79271.1 - 0.098 12.7 0.7 4.9 7.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 PRP79271.1 - 0.13 11.7 0.3 0.47 10.0 0.1 1.9 2 0 0 2 2 2 0 SHNi-TPR DMT_6 PF04342.12 PRP79271.1 - 0.25 11.5 9.0 1.7 8.9 1.0 2.5 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) DUF1126 PF06565.12 PRP79273.1 - 6.6e-95 312.0 3.1 3.2e-34 116.9 0.3 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_8 PF13833.6 PRP79273.1 - 0.0015 18.3 0.4 0.045 13.6 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 PRP79273.1 - 0.0052 17.2 1.2 0.18 12.2 0.0 3.2 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP79273.1 - 0.046 13.3 1.8 6.3 6.6 0.0 3.5 3 0 0 3 3 3 0 EF hand Glutaredoxin PF00462.24 PRP79274.1 - 3.3e-20 72.0 0.1 4.6e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 PRP79274.1 - 2.4e-05 24.6 0.1 3.7e-05 24.0 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 PRP79274.1 - 0.00012 22.4 0.0 0.00015 22.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP79274.1 - 0.0017 18.6 0.0 0.0026 18.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 PRP79274.1 - 0.0068 16.8 0.1 0.011 16.2 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 PRP79274.1 - 0.014 15.3 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein GST_N PF02798.20 PRP79274.1 - 0.014 15.7 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin PF00085.20 PRP79274.1 - 0.014 15.4 0.1 0.015 15.3 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 PRP79274.1 - 0.015 15.3 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.20 PRP79274.1 - 0.04 13.7 0.1 0.059 13.1 0.1 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF953 PF06110.11 PRP79274.1 - 0.077 12.6 0.1 0.14 11.8 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) PHD PF00628.29 PRP79275.1 - 8.9e-17 60.7 24.5 4e-10 39.4 7.1 3.5 3 0 0 3 3 3 2 PHD-finger Zf_RING PF16744.5 PRP79275.1 - 0.00099 19.2 13.9 0.0072 16.4 8.3 3.3 2 1 0 2 2 2 1 KIAA1045 RING finger FANCL_C PF11793.8 PRP79275.1 - 0.0038 17.4 8.8 0.1 12.8 0.6 2.7 1 1 1 2 2 2 2 FANCL C-terminal domain Prok-RING_1 PF14446.6 PRP79275.1 - 0.008 16.1 3.4 0.008 16.1 3.4 3.8 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 PRP79275.1 - 0.026 14.8 16.3 0.082 13.2 1.1 3.3 2 1 0 3 3 3 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 PRP79275.1 - 0.026 14.1 0.7 0.026 14.1 0.7 2.6 4 0 0 4 4 4 0 Zinc-ribbon, C4HC2 type zf-PHD-like PF15446.6 PRP79275.1 - 0.11 12.2 3.6 0.68 9.5 1.2 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.6 PRP79275.1 - 0.97 9.6 12.4 3.6 7.8 1.8 3.5 2 1 0 3 3 3 0 PHD-zinc-finger like domain PHD_2 PF13831.6 PRP79275.1 - 3.8 7.2 14.7 0.44 10.1 1.4 3.3 3 0 0 3 3 3 0 PHD-finger zf-RING-like PF08746.11 PRP79275.1 - 6 7.3 15.3 0.19 12.1 0.3 3.2 3 0 0 3 3 3 0 RING-like domain Dabb PF07876.12 PRP79276.1 - 4.8e-17 62.4 0.1 5.2e-17 62.2 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ABM PF03992.16 PRP79276.1 - 0.068 13.3 0.0 0.077 13.1 0.0 1.1 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase TPR_2 PF07719.17 PRP79278.1 - 0.0036 17.3 0.3 0.0089 16.1 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP79278.1 - 0.015 16.1 1.1 0.041 14.7 0.4 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79278.1 - 0.032 14.4 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP79278.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 PRP79278.1 - 0.12 12.8 0.1 0.41 11.2 0.0 1.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 PRP79278.1 - 0.12 12.7 0.7 0.27 11.6 0.6 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP79278.1 - 0.15 11.7 0.0 2.9 7.7 0.0 2.1 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 PRP79279.1 - 0.15 12.7 0.1 0.34 11.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Kinesin PF00225.23 PRP79280.1 - 9.8e-98 327.1 0.0 9.8e-98 327.1 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PRP79280.1 - 7.5e-14 51.9 0.0 7.5e-14 51.9 0.0 3.4 4 1 0 4 4 4 1 Microtubule binding FlbD PF06289.11 PRP79280.1 - 0.06 13.0 1.7 13 5.4 0.0 3.1 3 0 0 3 3 3 0 Flagellar and Swarming motility proteins DUF413 PF04219.12 PRP79280.1 - 1.8 8.6 6.1 11 6.1 3.6 3.0 2 1 0 2 2 2 0 Protein of unknown function, DUF Tim17 PF02466.19 PRP79281.1 - 1.8e-25 89.4 4.5 2.4e-25 89.1 4.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 PRP79281.1 - 9.5 6.1 13.9 0.18 11.6 2.5 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Arf PF00025.21 PRP79282.1 - 5.6e-42 143.1 0.0 1.1e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PRP79282.1 - 1.7e-13 50.5 0.0 3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79282.1 - 6.2e-11 42.6 0.0 1.8e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP79282.1 - 2.2e-08 33.7 0.0 5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PRP79282.1 - 4.2e-07 30.0 0.0 1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PRP79282.1 - 2.8e-05 23.5 5.8 0.0011 18.2 0.0 3.2 2 1 1 3 3 3 2 G-protein alpha subunit GTP_EFTU PF00009.27 PRP79282.1 - 0.002 17.7 3.0 1.1 8.8 0.1 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP79282.1 - 0.0027 17.1 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_21 PF13304.6 PRP79282.1 - 0.0052 16.6 0.0 0.0052 16.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 PRP79282.1 - 0.015 14.8 0.2 0.028 13.9 0.2 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_15 PF13175.6 PRP79282.1 - 0.03 14.0 0.1 0.03 14.0 0.1 2.3 2 1 0 2 2 1 0 AAA ATPase domain AAA_27 PF13514.6 PRP79282.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.9 2 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 PRP79282.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.6 2 1 0 2 2 1 0 ABC transporter Dynamin_N PF00350.23 PRP79282.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.0 2 1 0 2 2 1 0 Dynamin family Borrelia_P83 PF05262.11 PRP79282.1 - 9.4 4.6 30.2 14 4.0 30.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_1 PF00515.28 PRP79283.1 - 3.5e-08 32.9 1.8 0.034 14.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP79283.1 - 2.1e-07 31.3 2.0 0.0066 16.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP79283.1 - 3.7e-07 30.4 0.5 1 10.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP79283.1 - 4.5e-07 29.8 4.1 0.00013 22.1 0.6 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP79283.1 - 5.4e-07 29.2 1.3 0.05 13.3 0.0 3.5 3 0 0 3 3 3 3 TPR repeat TPR_16 PF13432.6 PRP79283.1 - 5.4e-07 30.2 0.1 0.084 13.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP79283.1 - 8e-07 28.7 9.0 0.013 15.6 0.0 5.8 7 0 0 7 7 7 2 Tetratricopeptide repeat MAS20 PF02064.15 PRP79283.1 - 0.00067 19.8 1.6 0.025 14.7 0.6 2.4 2 1 0 2 2 2 1 MAS20 protein import receptor TPR_12 PF13424.6 PRP79283.1 - 0.0011 19.3 4.4 0.48 10.8 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 PRP79283.1 - 0.028 14.8 0.1 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79283.1 - 0.037 14.2 4.9 21 5.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP79283.1 - 0.36 11.1 2.8 21 5.4 0.1 2.8 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RNA_POL_M_15KD PF02150.16 PRP79284.1 - 1.8e-07 30.9 0.5 3.2e-07 30.1 0.5 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Methyltransf_25 PF13649.6 PRP79284.1 - 0.00043 20.9 0.0 0.0013 19.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 PRP79284.1 - 0.0006 19.0 0.0 0.00092 18.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 PRP79284.1 - 0.00094 19.8 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 PRP79284.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Nudix_N_2 PF14803.6 PRP79284.1 - 0.031 14.2 0.2 0.078 12.9 0.2 1.7 1 0 0 1 1 1 0 Nudix N-terminal FtsJ PF01728.19 PRP79284.1 - 0.058 13.5 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Pkinase_Tyr PF07714.17 PRP79285.1 - 3.5e-21 75.7 0.1 2.5e-15 56.5 0.0 2.9 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 PRP79285.1 - 2.9e-20 71.8 48.3 3.1e-06 26.8 8.5 7.2 5 2 1 7 7 7 6 Leucine rich repeat Pkinase PF00069.25 PRP79285.1 - 1e-16 61.1 0.1 2.7e-11 43.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain LRR_4 PF12799.7 PRP79285.1 - 1.7e-16 60.1 54.4 7.2e-05 23.1 0.2 7.6 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP79285.1 - 2.5e-11 43.9 2.2 7.2e-11 42.4 2.2 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP79285.1 - 0.00088 19.5 56.7 0.09 13.4 1.2 12.4 13 1 0 13 13 13 3 Leucine Rich Repeat LRR_9 PF14580.6 PRP79285.1 - 0.78 9.2 10.2 5.9 6.4 1.5 3.3 2 1 1 3 3 3 0 Leucine-rich repeat UDPG_MGDP_dh_N PF03721.14 PRP79287.1 - 2.9e-54 183.5 0.6 1.5e-53 181.1 0.1 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 PRP79287.1 - 5.4e-32 110.3 0.1 2e-30 105.3 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 PRP79287.1 - 1.7e-30 105.0 0.1 6.4e-30 103.2 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain OTCace PF00185.24 PRP79287.1 - 1.7e-05 24.9 0.3 0.012 15.7 0.2 2.3 2 0 0 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain F420_oxidored PF03807.17 PRP79287.1 - 0.0013 19.3 1.7 2.5 8.8 0.0 3.6 3 2 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent DpaA_N PF16924.5 PRP79287.1 - 0.0013 18.8 0.1 0.37 10.9 0.0 3.3 3 0 0 3 3 3 1 Dipicolinate synthase subunit A N-terminal domain Shikimate_DH PF01488.20 PRP79287.1 - 0.0015 18.6 0.4 0.25 11.4 0.1 3.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 PRP79287.1 - 0.016 15.1 0.3 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_7 PF13241.6 PRP79287.1 - 0.028 14.8 0.1 0.22 12.0 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_2 PF03446.15 PRP79287.1 - 0.034 14.3 0.2 0.82 9.8 0.0 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase EspA PF03433.13 PRP79287.1 - 0.053 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 EspA-like secreted protein Sacchrp_dh_NADP PF03435.18 PRP79287.1 - 0.16 12.2 1.1 6.2 7.1 0.1 2.8 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 PRP79287.1 - 0.18 11.8 2.2 6.5 6.7 0.3 3.0 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TPR_1 PF00515.28 PRP79288.1 - 2.1e-19 68.5 0.6 0.0001 21.9 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 PRP79288.1 - 9.5e-17 59.7 6.4 6.3e-05 22.8 0.1 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 PRP79288.1 - 1.5e-11 44.1 5.9 0.051 14.4 0.0 5.8 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79288.1 - 1.9e-11 43.2 4.9 0.002 18.2 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP79288.1 - 3e-11 42.8 4.0 0.0013 18.4 0.0 5.7 5 1 1 6 6 6 3 TPR repeat TPR_17 PF13431.6 PRP79288.1 - 8.6e-10 38.3 4.1 0.0026 18.0 0.1 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP79288.1 - 5.1e-09 36.6 2.7 0.035 14.7 0.7 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP79288.1 - 9.5e-06 26.0 6.2 0.025 15.1 0.3 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP79288.1 - 7.5e-05 22.8 2.2 0.19 11.9 0.0 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP79288.1 - 0.00013 22.2 8.1 0.22 11.9 0.1 4.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP79288.1 - 0.00029 21.3 0.3 0.27 11.9 0.2 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP79288.1 - 0.00043 20.1 4.6 0.94 9.7 0.1 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat BTAD PF03704.17 PRP79288.1 - 0.0007 20.1 2.3 0.89 10.0 0.5 3.3 2 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 PRP79288.1 - 0.00082 19.2 2.5 0.12 12.3 0.3 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4810 PF16068.5 PRP79288.1 - 0.001 19.5 0.7 1.2 9.7 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4810) TPR_20 PF14561.6 PRP79288.1 - 0.0063 16.8 4.3 4 7.9 1.2 3.9 2 2 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 PRP79288.1 - 0.02 15.0 2.1 1.2 9.3 0.0 3.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain MRP-S27 PF10037.9 PRP79288.1 - 0.021 13.7 3.3 0.031 13.1 3.3 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF1641 PF07849.11 PRP79288.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Macro PF01661.21 PRP79289.1 - 9.9e-22 77.2 0.0 1.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Macro domain F-box-like PF12937.7 PRP79289.1 - 3e-07 30.2 0.6 3.5e-06 26.8 1.9 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP79289.1 - 5.1e-07 29.4 2.2 1.3e-06 28.1 2.2 1.7 1 0 0 1 1 1 1 F-box domain NAD_binding_10 PF13460.6 PRP79290.1 - 0.0019 18.1 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Peptidase_C48 PF02902.19 PRP79291.1 - 2.9e-06 27.3 0.2 0.00092 19.1 0.0 2.1 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain adh_short PF00106.25 PRP79292.1 - 6.6e-22 77.9 0.1 1.2e-21 77.1 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP79292.1 - 1.7e-17 63.8 0.0 2.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP79292.1 - 1.7e-10 41.1 0.0 4.4e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PRP79292.1 - 1.9e-05 24.3 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP79292.1 - 0.00045 19.7 0.0 0.0012 18.4 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PRP79292.1 - 0.00072 19.5 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3H PF02829.14 PRP79292.1 - 0.093 13.0 0.1 2.5 8.5 0.0 2.2 2 0 0 2 2 2 0 3H domain DEK_C PF08766.11 PRP79293.1 - 1.9e-06 27.7 1.7 4.1e-06 26.6 1.7 1.6 1 1 0 1 1 1 1 DEK C terminal domain PC4 PF02229.16 PRP79293.1 - 2.4e-05 23.9 0.0 4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Complex1_LYR PF05347.15 PRP79294.1 - 1.2e-12 47.6 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PRP79294.1 - 0.034 14.9 0.1 0.051 14.3 0.1 1.3 1 1 0 1 1 1 0 Complex1_LYR-like HSP20 PF00011.21 PRP79295.1 - 5.8e-20 71.3 0.2 8e-20 70.9 0.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP79295.1 - 4.3e-06 26.2 0.0 5.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Ssl1 PF04056.14 PRP79298.1 - 1.8e-75 253.0 0.0 2.4e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 PRP79298.1 - 1.6e-12 47.4 8.4 1.6e-12 47.4 8.4 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 PRP79298.1 - 1.3e-09 38.7 0.2 4e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 PRP79298.1 - 1.7e-05 25.1 0.1 3.1e-05 24.3 0.0 1.4 2 0 0 2 2 2 1 von Willebrand factor type A domain Sua5_yciO_yrdC PF01300.18 PRP79298.1 - 0.00039 20.0 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination DUF3668 PF12416.8 PRP79298.1 - 0.089 12.6 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Cep120 protein Tfb4 PF03850.14 PRP79298.1 - 0.41 10.1 4.1 0.98 8.8 3.2 2.0 1 1 1 2 2 2 0 Transcription factor Tfb4 FlhC PF05280.11 PRP79298.1 - 0.75 9.5 3.8 1.5 8.5 3.8 1.5 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) ABC_membrane PF00664.23 PRP79299.1 - 6.8e-111 370.3 17.6 6.3e-58 196.6 6.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP79299.1 - 1e-68 230.1 0.1 2e-34 119.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter CLU PF13236.6 PRP79299.1 - 6.7e-55 186.3 0.0 1.5e-54 185.2 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria SMC_N PF02463.19 PRP79299.1 - 3.7e-16 59.2 0.0 8.4e-07 28.6 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 PRP79299.1 - 4.7e-09 35.6 0.1 0.0015 17.4 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 PRP79299.1 - 2.3e-07 31.3 1.5 0.0085 16.5 0.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 PRP79299.1 - 1.3e-06 28.1 0.8 0.0064 16.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain eIF3_p135 PF12807.7 PRP79299.1 - 2.5e-05 24.4 0.1 6.9e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 AAA_30 PF13604.6 PRP79299.1 - 2.8e-05 23.9 0.4 0.013 15.2 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 PRP79299.1 - 3.3e-05 24.3 1.1 1.4 9.3 0.1 4.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PRP79299.1 - 0.00016 21.6 2.1 0.44 10.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 PRP79299.1 - 0.00037 20.8 4.7 1.2 9.4 0.3 4.8 3 2 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 PRP79299.1 - 0.00038 19.8 0.3 1.7 7.9 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_7 PF12775.7 PRP79299.1 - 0.0011 18.5 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 PRP79299.1 - 0.0016 18.3 0.0 0.29 10.8 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 PRP79299.1 - 0.0021 17.3 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 PRP79299.1 - 0.0036 17.5 3.8 0.89 9.8 0.3 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 PRP79299.1 - 0.0058 17.2 5.7 0.1 13.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain SRP54 PF00448.22 PRP79299.1 - 0.0072 16.0 0.0 1.9 8.1 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain TPR_1 PF00515.28 PRP79299.1 - 0.0073 16.1 0.0 0.048 13.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat IstB_IS21 PF01695.17 PRP79299.1 - 0.018 14.8 0.6 62 3.2 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_33 PF13671.6 PRP79299.1 - 0.024 14.8 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 PRP79299.1 - 0.024 14.5 0.4 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_21 PF13304.6 PRP79299.1 - 0.031 14.1 1.6 11 5.8 0.1 4.0 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 PRP79299.1 - 0.041 13.9 0.1 13 5.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) TPR_14 PF13428.6 PRP79299.1 - 0.052 14.4 0.0 0.29 12.1 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP79299.1 - 0.06 13.5 0.0 0.29 11.3 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF815 PF05673.13 PRP79299.1 - 0.1 11.7 0.1 8.9 5.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 PRP79299.1 - 0.11 12.2 0.1 8.8 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain LRR19-TM PF15176.6 PRP79299.1 - 0.12 12.4 0.0 0.45 10.5 0.0 2.0 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Rad17 PF03215.15 PRP79299.1 - 0.12 12.3 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 PRP79299.1 - 0.12 12.2 1.1 32 4.4 0.0 3.5 3 1 1 4 4 4 0 NTPase DUF87 PF01935.17 PRP79299.1 - 0.15 12.1 4.1 9.4 6.3 0.0 3.4 3 0 0 3 3 2 0 Helicase HerA, central domain PLDc_N PF13396.6 PRP79300.1 - 3.5e-09 36.4 3.2 8.6e-09 35.2 3.2 1.7 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal DUF4199 PF13858.6 PRP79300.1 - 0.05 14.0 0.4 0.068 13.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Cecropin PF00272.19 PRP79300.1 - 0.17 11.7 0.8 0.27 11.0 0.8 1.3 1 0 0 1 1 1 0 Cecropin family Herpes_LMP1 PF05297.11 PRP79300.1 - 1.6 7.8 5.8 1.9 7.6 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) zf-MYND PF01753.18 PRP79301.1 - 4.7e-11 42.6 15.8 4.7e-11 42.6 15.8 1.9 2 0 0 2 2 2 1 MYND finger CDC37_M PF08565.11 PRP79301.1 - 6.3e-11 42.2 0.8 1.1e-09 38.2 0.3 2.3 1 1 1 2 2 2 1 Cdc37 Hsp90 binding domain Baculo_LEF-11 PF06385.12 PRP79301.1 - 0.017 15.6 0.1 0.094 13.2 0.1 2.2 1 1 0 1 1 1 0 Baculovirus LEF-11 protein LRR_8 PF13855.6 PRP79303.1 - 9e-63 207.9 109.2 5.4e-09 35.7 5.4 14.9 6 1 10 17 17 17 17 Leucine rich repeat LRR_4 PF12799.7 PRP79303.1 - 1.3e-41 139.9 115.6 0.0001 22.6 1.6 17.4 10 3 8 19 19 19 16 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP79303.1 - 1.2e-09 37.4 106.3 1.6 9.6 1.0 25.3 26 2 2 28 28 28 6 Leucine Rich Repeat MitoNEET_N PF10660.9 PRP79303.1 - 1.5 8.9 4.2 7.1 6.7 0.0 4.2 5 0 0 5 5 5 0 Iron-containing outer mitochondrial membrane protein N-terminus GMC_oxred_N PF00732.19 PRP79304.1 - 1.2e-31 110.2 0.0 2.6e-31 109.1 0.0 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP79304.1 - 1.4e-12 48.4 0.0 2.5e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PRP79304.1 - 0.00024 21.3 0.1 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP79304.1 - 0.015 14.9 0.3 0.071 12.7 0.1 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP79304.1 - 0.018 14.3 0.1 0.056 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP79304.1 - 0.038 12.7 0.0 0.074 11.7 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 PRP79304.1 - 0.042 12.9 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 PRP79304.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 PRP79304.1 - 0.072 12.2 0.1 0.53 9.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 PRP79304.1 - 0.16 11.2 0.0 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase_Tyr PF07714.17 PRP79305.1 - 4.8e-69 232.5 0.0 7e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79305.1 - 9e-51 172.8 0.0 1.4e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP79305.1 - 8.3e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP79305.1 - 0.00069 18.7 0.1 0.051 12.5 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP79305.1 - 0.01 14.7 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase dCache_1 PF02743.18 PRP79305.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Cache domain FTA2 PF13095.6 PRP79305.1 - 0.028 14.0 0.3 2.9 7.4 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP79305.1 - 0.042 13.2 0.0 0.093 12.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Renin_r PF07850.14 PRP79305.1 - 0.18 12.4 1.1 1.3 9.6 0.0 2.6 2 0 0 2 2 2 0 Renin receptor-like protein Protocadherin PF08374.11 PRP79305.1 - 0.29 11.1 0.5 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Protocadherin DUF2975 PF11188.8 PRP79305.1 - 2.5 8.0 7.8 0.52 10.2 0.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Nexin_C PF08628.12 PRP79307.1 - 0.031 14.8 3.4 0.049 14.2 0.1 2.8 3 1 0 3 3 3 0 Sorting nexin C terminal Vinculin PF01044.19 PRP79308.1 - 1.9e-05 23.1 41.8 2.7e-05 22.7 4.0 3.2 2 1 0 3 3 3 3 Vinculin family AAA_6 PF12774.7 PRP79308.1 - 0.37 9.7 2.9 1.5 7.7 0.2 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DinB_2 PF12867.7 PRP79308.1 - 9.6 6.7 9.5 1.3 9.5 1.0 3.3 3 0 0 3 3 3 0 DinB superfamily Yippee-Mis18 PF03226.14 PRP79309.1 - 2.5e-06 27.6 1.9 0.00015 21.9 0.6 2.3 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rhodanese PF00581.20 PRP79310.1 - 1.5e-11 44.7 0.0 3.3e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain AAA PF00004.29 PRP79312.1 - 1.6e-42 145.1 0.0 3.2e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP79312.1 - 2.5e-12 46.4 0.1 7e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PRP79312.1 - 6.9e-10 38.7 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 PRP79312.1 - 1.8e-07 31.7 0.0 9e-05 22.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 PRP79312.1 - 1.8e-06 28.0 0.0 2.4e-05 24.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PRP79312.1 - 8.8e-06 25.6 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PRP79312.1 - 1.6e-05 25.1 0.0 3.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PRP79312.1 - 0.0003 21.1 0.3 0.023 15.0 0.0 2.7 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 PRP79312.1 - 0.001 18.3 0.0 0.0031 16.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 PRP79312.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 PRP79312.1 - 0.0032 18.0 0.0 0.0094 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PRP79312.1 - 0.0037 17.0 0.0 0.0079 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 PRP79312.1 - 0.0042 16.4 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 PRP79312.1 - 0.0045 16.7 0.1 0.023 14.4 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 PRP79312.1 - 0.0053 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 PRP79312.1 - 0.0073 15.8 0.0 0.017 14.6 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 PRP79312.1 - 0.0078 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 PRP79312.1 - 0.015 14.4 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 PRP79312.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PRP79312.1 - 0.02 14.6 0.1 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 PRP79312.1 - 0.022 14.5 0.3 0.062 13.0 0.0 2.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 PRP79312.1 - 0.024 14.7 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PRP79312.1 - 0.026 14.7 0.0 0.077 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 PRP79312.1 - 0.027 14.4 0.0 0.063 13.2 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA_28 PF13521.6 PRP79312.1 - 0.03 14.6 0.1 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 PRP79312.1 - 0.038 13.7 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain Thymidylate_kin PF02223.17 PRP79312.1 - 0.072 12.8 0.7 14 5.3 0.4 2.7 2 1 1 3 3 3 0 Thymidylate kinase ATPase PF06745.13 PRP79312.1 - 0.079 12.3 0.1 0.29 10.4 0.0 2.0 3 0 0 3 3 3 0 KaiC PhoH PF02562.16 PRP79312.1 - 0.092 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 PRP79312.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 PRP79312.1 - 0.12 12.3 0.8 0.26 11.1 0.0 2.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 PRP79312.1 - 0.12 12.1 1.1 0.37 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ZapB PF06005.12 PRP79312.1 - 1.4 9.4 6.2 0.16 12.4 0.9 2.2 3 0 0 3 3 1 0 Cell division protein ZapB AAA_13 PF13166.6 PRP79312.1 - 1.6 7.3 3.9 4.2 5.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain BTB_2 PF02214.22 PRP79313.1 - 1e-21 77.1 1.0 2.5e-21 75.8 0.2 2.1 2 0 0 2 2 2 1 BTB/POZ domain Jnk-SapK_ap_N PF09744.9 PRP79313.1 - 0.0056 16.9 2.0 0.0089 16.3 2.0 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 dCache_2 PF08269.11 PRP79313.1 - 0.041 13.1 2.3 0.061 12.5 2.3 1.2 1 0 0 1 1 1 0 Cache domain DUF4962 PF16332.5 PRP79313.1 - 0.042 12.4 0.4 0.053 12.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) DUF2205 PF10224.9 PRP79313.1 - 0.16 12.0 3.9 0.39 10.7 3.9 1.7 1 0 0 1 1 1 0 Short coiled-coil protein ASD2 PF08687.11 PRP79313.1 - 0.19 11.3 5.9 0.28 10.7 5.9 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 OmpH PF03938.14 PRP79313.1 - 0.39 11.1 4.3 0.71 10.2 4.3 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 PRP79313.1 - 0.52 10.4 7.2 1 9.4 7.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Aldo_ket_red PF00248.21 PRP79314.1 - 1.3e-67 228.0 0.7 1.5e-67 227.9 0.7 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CbiG_C PF01890.16 PRP79314.1 - 0.092 13.3 0.0 12 6.4 0.0 2.8 2 1 1 3 3 3 0 Cobalamin synthesis G C-terminus NAF PF03822.14 PRP79314.1 - 0.14 12.3 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 NAF domain Sec1 PF00995.23 PRP79315.1 - 6.3e-120 402.1 0.1 7.1e-120 401.9 0.1 1.0 1 0 0 1 1 1 1 Sec1 family LAG1-DNAbind PF09271.11 PRP79317.1 - 0.043 14.4 0.0 0.076 13.7 0.0 1.5 1 1 0 1 1 1 0 LAG1, DNA binding PseudoU_synth_2 PF00849.22 PRP79318.1 - 4.8e-15 56.0 2.3 8.8e-15 55.1 0.1 2.5 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 PRP79318.1 - 1.1e-06 28.2 0.9 4.2e-06 26.4 0.1 2.3 1 1 1 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.22 PRP79319.1 - 7e-22 78.2 0.0 1.3e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase ChapFlgA PF13144.6 PRP79319.1 - 0.046 13.8 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Chaperone for flagella basal body P-ring formation DNA_ligase_OB PF03120.16 PRP79319.1 - 0.091 12.7 0.9 17 5.4 0.1 2.3 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain EGF_2 PF07974.13 PRP79320.1 - 0.022 15.2 5.9 0.056 13.8 5.9 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 PRP79320.1 - 1.3 9.8 5.4 0.94 10.2 2.4 2.4 1 1 1 2 2 2 0 Human growth factor-like EGF Pkinase_Tyr PF07714.17 PRP79321.1 - 5.2e-20 71.8 0.1 7.8e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79321.1 - 5.2e-17 62.1 0.1 8.8e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP79321.1 - 6.8e-06 26.5 0.4 2.6e-05 24.7 0.4 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_8 PF13855.6 PRP79321.1 - 2.1e-05 24.2 2.3 2.1e-05 24.2 2.3 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PRP79321.1 - 0.062 13.7 8.3 0.17 12.4 0.7 3.8 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) PMP1_2 PF08114.11 PRP79321.1 - 0.12 12.2 0.7 0.25 11.1 0.7 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Syndecan PF01034.20 PRP79321.1 - 0.25 11.3 0.4 0.49 10.4 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain SprA-related PF12118.8 PRP79321.1 - 0.7 9.0 16.7 1.2 8.2 16.7 1.4 1 0 0 1 1 1 0 SprA-related family Hamartin PF04388.12 PRP79321.1 - 1.5 7.4 14.1 2 6.9 14.1 1.1 1 0 0 1 1 1 0 Hamartin protein zf-H2C2_2 PF13465.6 PRP79323.1 - 1.4e-15 56.9 24.7 3.4e-09 36.7 1.5 4.8 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 PRP79323.1 - 9.4e-12 44.7 31.1 0.0023 18.3 0.9 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP79323.1 - 9.1e-10 38.5 28.9 0.0077 17.0 0.6 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PRP79323.1 - 0.014 15.7 10.9 0.76 10.1 0.3 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 PRP79323.1 - 0.043 14.0 10.4 0.66 10.1 0.1 3.9 2 1 2 4 4 4 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 PRP79323.1 - 0.23 11.8 15.4 4.2 7.8 0.2 4.1 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 PRP79323.1 - 0.91 10.0 10.4 6.1 7.4 1.7 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger CCAP PF11105.8 PRP79323.1 - 2 8.4 4.7 21 5.1 0.1 2.8 1 1 2 3 3 3 0 Arthropod cardioacceleratory peptide 2a zf-LYAR PF08790.11 PRP79323.1 - 9.5 6.2 10.1 40 4.2 0.0 3.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Alk_phosphatase PF00245.20 PRP79324.1 - 3.1e-95 319.6 0.1 4e-95 319.2 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 PRP79324.1 - 0.00056 19.4 0.0 0.002 17.5 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF4934 PF16288.5 PRP79324.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) Autophagy_act_C PF03987.15 PRP79325.1 - 4.1e-05 24.1 0.2 5.9e-05 23.6 0.2 1.5 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Aminotran_1_2 PF00155.21 PRP79326.1 - 7.5e-32 110.9 0.0 9e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 PRP79326.1 - 5.1e-09 35.4 0.0 6.4e-09 35.1 0.0 1.3 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 PRP79326.1 - 0.0022 17.4 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 PRP79326.1 - 0.092 11.6 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Allinase Cir_N PF10197.9 PRP79327.1 - 0.00035 20.7 6.8 0.00035 20.7 6.8 6.4 6 1 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF5550 PF17704.1 PRP79327.1 - 0.019 15.1 1.3 0.041 14.0 1.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5550) WD40 PF00400.32 PRP79328.1 - 7.9e-26 89.8 19.1 2.3e-05 25.0 0.5 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 PRP79328.1 - 3e-14 52.9 0.1 6.1e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.24 PRP79328.1 - 1.1e-12 47.8 0.1 2.7e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 SH2 domain Pkinase PF00069.25 PRP79328.1 - 5.6e-11 42.3 0.2 1.1e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 PRP79328.1 - 2.1e-10 41.0 0.0 8.6e-10 39.1 0.0 2.2 1 0 0 1 1 1 1 PH domain ANAPC4_WD40 PF12894.7 PRP79328.1 - 1.4e-08 34.9 0.2 0.0088 16.3 0.0 5.3 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 PRP79328.1 - 1.4e-06 28.1 0.3 4.8e-06 26.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like PH_11 PF15413.6 PRP79328.1 - 0.00052 20.4 0.0 0.003 18.0 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Histone PF00125.24 PRP79329.1 - 4.8e-30 104.6 2.7 5.4e-30 104.4 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PARP PF00644.20 PRP79330.1 - 1.1e-40 139.4 0.0 1.1e-40 139.4 0.0 3.5 3 1 1 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PRP79330.1 - 8.2e-37 126.3 1.7 8.2e-37 126.3 1.7 3.7 4 1 0 4 4 4 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 PRP79330.1 - 1.3e-24 86.0 2.3 1.3e-24 86.0 2.3 3.0 2 0 0 2 2 2 1 WGR domain SAP PF02037.27 PRP79330.1 - 0.18 11.6 6.0 0.052 13.3 1.5 2.6 2 1 0 2 2 2 0 SAP domain tRNA-synt_1 PF00133.22 PRP79331.1 - 2.2e-217 723.1 0.0 3.7e-217 722.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PRP79331.1 - 3.6e-24 85.5 0.0 5.5e-23 81.6 0.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PRP79331.1 - 1.8e-16 59.9 0.8 6.3e-05 21.9 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PRP79331.1 - 0.00031 20.2 0.0 0.0021 17.5 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 PRP79332.1 - 6.5e-26 91.3 0.0 1.1e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79332.1 - 8.4e-23 81.0 0.1 1.4e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP79332.1 - 0.0015 19.0 0.2 0.0045 17.5 0.2 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP79332.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HATPase_c PF02518.26 PRP79332.1 - 0.025 15.1 0.0 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pox_int_trans PF05718.12 PRP79335.1 - 0.04 12.6 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus intermediate transcription factor Pkinase PF00069.25 PRP79337.1 - 2.3e-26 92.7 0.1 3.9e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79337.1 - 2.7e-22 79.3 0.1 5e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP79337.1 - 6.4e-08 33.0 4.7 1.8e-07 31.5 4.7 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF1191 PF06697.12 PRP79337.1 - 0.0011 18.7 0.1 0.0034 17.2 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1191) Kinase-like PF14531.6 PRP79337.1 - 0.004 16.5 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HATPase_c PF02518.26 PRP79337.1 - 0.032 14.7 0.0 0.077 13.5 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rpn3_C PF08375.11 PRP79338.1 - 8.7e-25 86.9 1.7 3e-24 85.2 1.7 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 PRP79338.1 - 1.1e-22 80.5 0.8 3.6e-22 78.8 0.2 2.2 2 0 0 2 2 2 1 PCI domain DUF4368 PF14287.6 PRP79338.1 - 0.011 16.0 0.1 0.088 13.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) DUF4519 PF15012.6 PRP79338.1 - 0.054 13.7 0.5 12 6.2 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Ank_4 PF13637.6 PRP79341.1 - 1.3e-20 73.5 0.1 2.7e-12 46.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP79341.1 - 2.7e-15 56.7 0.0 3.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP79341.1 - 4e-14 52.5 0.0 2.1e-08 34.2 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP79341.1 - 3.8e-11 42.9 0.2 3.8e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 PRP79341.1 - 2.6e-05 24.2 0.0 0.2 12.3 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Phage_T7_Capsid PF05396.11 PRP79341.1 - 0.048 14.0 0.3 0.063 13.6 0.3 1.2 1 0 0 1 1 1 0 Phage T7 capsid assembly protein ACOX PF01756.19 PRP79342.1 - 7.2e-20 71.3 0.1 3.6e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PRP79342.1 - 2.2e-11 43.8 0.3 4.8e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 PRP79342.1 - 0.00013 22.2 0.0 0.00047 20.4 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Tcf25 PF04910.14 PRP79343.1 - 2.1e-78 263.9 4.0 3.7e-78 263.0 4.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_14 PF13428.6 PRP79343.1 - 6.4e-05 23.4 0.0 0.2 12.6 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP79343.1 - 0.012 15.8 0.0 1.5 9.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP79343.1 - 0.26 11.2 0.9 45 4.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP19 PF11022.8 PRP79343.1 - 1.9 8.9 8.9 5.1 7.5 0.1 2.8 2 0 0 2 2 2 0 ATP synthase subunit K Stm1_N PF09598.10 PRP79343.1 - 2.2 9.2 8.9 0.95 10.4 4.7 2.5 2 0 0 2 2 2 0 Stm1 Peptidase_C37 PF05416.12 PRP79343.1 - 2.2 6.7 11.2 3.1 6.2 11.2 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase GREB1 PF15782.5 PRP79343.1 - 4.9 4.1 11.5 6.5 3.7 11.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 PRP79343.1 - 7.4 4.7 15.9 12 4.1 15.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.18 PRP79344.1 - 0.019 15.1 0.3 0.034 14.3 0.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.7 PRP79344.1 - 0.02 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 PRP79344.1 - 0.028 14.4 0.2 0.059 13.4 0.0 1.7 2 0 0 2 2 2 0 PAS fold DUF2408 PF10303.9 PRP79344.1 - 0.031 14.8 0.0 0.046 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) PAS_4 PF08448.10 PRP79344.1 - 0.051 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF937 PF06078.11 PRP79345.1 - 6.7 7.3 17.8 94 3.6 17.8 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF937) USP8_dimer PF08969.11 PRP79346.1 - 4.8e-09 36.4 0.0 9.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain PX PF00787.24 PRP79346.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 PX domain KOG2701 PF09762.9 PRP79347.1 - 9.1e-59 198.6 0.0 9.1e-59 198.6 0.0 4.4 2 1 0 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) Ndc80_HEC PF03801.13 PRP79347.1 - 0.001 18.7 0.2 0.0053 16.4 0.0 2.2 2 0 0 2 2 2 1 HEC/Ndc80p family Aurora-A_bind PF09041.10 PRP79347.1 - 0.092 12.8 0.2 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Aurora-A binding OSCP PF00213.18 PRP79347.1 - 3.5 7.7 15.5 0.37 10.9 9.3 2.7 2 1 0 2 2 2 0 ATP synthase delta (OSCP) subunit TF_Zn_Ribbon PF08271.12 PRP79349.1 - 0.0012 18.3 0.4 0.0028 17.1 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Homeodomain PF00046.29 PRP79350.1 - 3.1e-11 42.9 0.6 3.9e-11 42.6 0.6 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP79350.1 - 6.2e-07 29.2 1.5 9e-07 28.7 1.5 1.2 1 0 0 1 1 1 1 Homeobox KN domain COesterase PF00135.28 PRP79351.1 - 2.3e-41 142.2 0.0 3.2e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP79351.1 - 1.4e-05 25.0 0.0 5e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Mito_carr PF00153.27 PRP79352.1 - 3.9e-69 228.7 1.0 9e-25 86.4 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein PAS_8 PF13188.7 PRP79352.1 - 0.0036 17.3 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain Serine_protease PF18405.1 PRP79352.1 - 0.013 14.7 2.1 1.9 7.6 0.2 2.5 1 1 0 2 2 2 0 Gammaproteobacterial serine protease Zn_clus PF00172.18 PRP79352.1 - 0.02 15.0 2.2 0.055 13.6 2.2 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.7 PRP79352.1 - 0.13 12.6 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 PRP79352.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold SPW PF03779.14 PRP79352.1 - 0.25 10.9 1.0 22 4.8 0.2 2.7 2 0 0 2 2 2 0 SPW repeat Pro_isomerase PF00160.21 PRP79354.1 - 2.3e-13 50.7 0.0 3e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 PRP79356.1 - 2.3e-13 50.7 0.0 3.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAS_8 PF13188.7 PRP79357.1 - 0.00083 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 PRP79357.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 PRP79357.1 - 0.033 14.5 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain Mito_carr PF00153.27 PRP79358.1 - 5.1e-66 218.7 1.1 3.6e-25 87.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PRP79358.1 - 0.0024 17.1 2.0 0.86 8.7 0.2 2.6 1 1 0 2 2 2 2 Gammaproteobacterial serine protease SPW PF03779.14 PRP79358.1 - 3 7.5 6.7 11 5.6 0.2 3.0 3 0 0 3 3 3 0 SPW repeat Kelch_3 PF13415.6 PRP79359.1 - 4e-53 176.8 16.9 1.8e-09 37.6 0.1 7.2 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP79359.1 - 4e-40 135.2 7.5 8.4e-08 32.0 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PRP79359.1 - 6.8e-37 125.2 13.6 7.9e-10 38.6 0.1 6.7 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP79359.1 - 5.8e-36 121.6 6.4 2.6e-08 33.8 0.1 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PRP79359.1 - 1.4e-35 120.6 8.2 2.1e-07 30.4 0.3 6.4 6 0 0 6 6 6 6 Kelch motif BTB PF00651.31 PRP79359.1 - 3e-21 75.7 0.4 4.5e-21 75.2 0.4 1.3 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 PRP79359.1 - 6e-21 73.6 13.0 5.8e-05 22.9 0.1 7.4 7 1 0 7 7 7 5 Kelch motif RAG2 PF03089.14 PRP79359.1 - 0.008 15.2 0.7 5.3 5.9 0.0 4.1 3 2 1 4 4 4 1 Recombination activating protein 2 Pkinase_Tyr PF07714.17 PRP79360.1 - 2.9e-24 85.7 2.0 3.6e-24 85.4 0.3 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79360.1 - 3.7e-13 49.5 1.2 1.9e-12 47.1 1.2 2.1 1 1 0 1 1 1 1 Protein kinase domain PUF PF00806.19 PRP79360.1 - 0.00034 20.1 0.7 1 9.2 0.0 6.0 8 0 0 8 8 8 1 Pumilio-family RNA binding repeat ATP-synt_B PF00430.18 PRP79360.1 - 0.21 11.7 8.6 5.1 7.2 0.2 3.0 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Seryl_tRNA_N PF02403.22 PRP79360.1 - 0.51 10.6 13.6 0.29 11.4 9.1 3.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PKD_channel PF08016.12 PRP79362.1 - 7.9e-46 156.6 8.0 1.4e-45 155.8 8.0 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ank_2 PF12796.7 PRP79362.1 - 9.4e-07 29.3 0.1 0.0007 20.1 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79362.1 - 2e-06 28.2 3.3 1.6e-05 25.4 0.9 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP79362.1 - 0.00096 19.4 0.3 1.6 9.6 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 PRP79362.1 - 0.024 15.0 0.2 0.36 11.2 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 PRP79362.1 - 0.11 13.0 0.3 4.8 7.8 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat zf-4CXXC_R1 PF10497.9 PRP79363.1 - 0.00043 20.5 13.7 0.00085 19.5 13.7 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD PF00628.29 PRP79363.1 - 2.7 7.9 17.1 0.18 11.8 11.4 2.0 2 0 0 2 2 2 0 PHD-finger Macoilin PF09726.9 PRP79363.1 - 3.2 6.2 9.6 3.9 5.9 9.6 1.1 1 0 0 1 1 1 0 Macoilin family FYVE_2 PF02318.16 PRP79363.1 - 3.3 8.0 11.6 3.7 7.8 10.1 1.8 1 1 1 2 2 2 0 FYVE-type zinc finger DUF4769 PF15992.5 PRP79363.1 - 3.8 7.2 9.0 2 8.2 6.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) DSPc PF00782.20 PRP79364.1 - 7.1e-32 110.0 0.2 1.5e-31 109.0 0.2 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP79364.1 - 0.0008 19.0 0.1 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PRP79364.1 - 0.0044 17.1 0.2 0.15 12.1 0.0 2.6 3 0 0 3 3 3 1 Inositol hexakisphosphate TackOD1 PF18551.1 PRP79364.1 - 0.011 15.4 2.1 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Init_tRNA_PT PF04179.12 PRP79364.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain LIM PF00412.22 PRP79364.1 - 0.11 12.8 6.3 2.1 8.6 0.6 2.8 3 0 0 3 3 3 0 LIM domain HemN_C PF06969.16 PRP79364.1 - 0.19 11.8 0.6 24 5.1 0.1 2.7 2 1 1 3 3 3 0 HemN C-terminal domain ACBP PF00887.19 PRP79365.1 - 4.2e-22 78.1 0.4 8.4e-22 77.2 0.4 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Cellulase PF00150.18 PRP79365.1 - 3.6e-18 66.0 6.1 5.5e-18 65.4 6.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 PRP79365.1 - 0.0011 19.0 0.1 0.0032 17.5 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4434) SIS PF01380.22 PRP79366.1 - 1.2e-56 190.1 0.1 2.3e-31 108.4 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 PRP79366.1 - 1.2e-15 57.9 0.0 2.3e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 PRP79366.1 - 2e-10 40.6 0.0 4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 PRP79366.1 - 0.0013 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DUF3730 PF12530.8 PRP79368.1 - 8e-32 110.7 0.2 8e-32 110.7 0.2 3.9 5 0 0 5 5 5 1 Protein of unknown function (DUF3730) Focadhesin PF11229.8 PRP79368.1 - 1.4e-05 23.6 0.3 6.3e-05 21.4 0.1 2.0 2 0 0 2 2 2 1 Focadhesin NAGidase PF07555.13 PRP79369.1 - 9.4e-20 71.1 0.1 1.6e-19 70.4 0.1 1.4 1 1 0 1 1 1 1 beta-N-acetylglucosaminidase Ank_2 PF12796.7 PRP79370.1 - 8.1e-10 39.2 0.1 2e-09 37.9 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP79370.1 - 2e-09 36.9 0.2 0.031 14.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 PRP79370.1 - 5.3e-06 26.9 0.4 0.1 13.2 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP79370.1 - 2.2e-05 24.6 0.2 0.52 10.7 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP79370.1 - 2.4e-05 24.6 0.3 0.21 12.1 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeat DUF3910 PF13049.6 PRP79370.1 - 0.21 11.9 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) SNARE_assoc PF09335.11 PRP79373.1 - 4e-20 72.5 7.1 4e-20 72.5 7.1 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein Glycophorin_A PF01102.18 PRP79373.1 - 0.014 15.6 0.0 0.091 13.0 0.0 2.0 2 0 0 2 2 2 0 Glycophorin A Protocadherin PF08374.11 PRP79373.1 - 0.1 12.6 0.1 8.1 6.4 0.1 2.2 2 0 0 2 2 2 0 Protocadherin EssA PF10661.9 PRP79373.1 - 0.8 9.5 2.7 3.6 7.4 0.0 2.7 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein EssA Dynamitin PF04912.14 PRP79374.1 - 2.6e-74 250.9 25.5 3.3e-74 250.6 25.5 1.1 1 0 0 1 1 1 1 Dynamitin Baculo_PEP_C PF04513.12 PRP79374.1 - 0.0077 16.3 2.0 0.0077 16.3 2.0 4.2 2 2 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1796 PF08795.10 PRP79374.1 - 0.025 14.6 1.3 0.41 10.6 0.4 2.3 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) BLOC1_2 PF10046.9 PRP79374.1 - 1.5 9.2 23.5 0.39 11.0 2.5 5.0 1 1 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.6 PRP79374.1 - 3.6 8.0 23.9 3.2 8.2 5.0 4.0 2 1 2 4 4 4 0 Syntaxin-like protein Matrilin_ccoil PF10393.9 PRP79374.1 - 4.7 7.1 10.7 32 4.5 0.1 4.7 6 0 0 6 6 6 0 Trimeric coiled-coil oligomerisation domain of matrilin Laminin_II PF06009.12 PRP79374.1 - 4.9 7.2 23.8 0.025 14.6 4.0 4.2 1 1 2 4 4 4 0 Laminin Domain II TsaE PF02367.17 PRP79375.1 - 1.4e-29 102.7 0.0 2.2e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 PRP79375.1 - 0.0011 19.1 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP79375.1 - 0.004 16.8 0.0 0.0057 16.3 0.0 1.1 1 0 0 1 1 1 1 Ras family NACHT PF05729.12 PRP79375.1 - 0.054 13.4 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 PRP79375.1 - 0.075 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 PRP79375.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 PRP79375.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Longin PF13774.6 PRP79376.1 - 3.1e-19 68.8 0.1 9.4e-19 67.2 0.1 1.8 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 PRP79376.1 - 2.8e-14 52.7 0.0 6.1e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin Glutaredoxin2_C PF04399.13 PRP79376.1 - 0.16 11.8 1.0 0.6 10.0 0.2 2.2 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain Ribosomal_S25 PF03297.15 PRP79377.1 - 8.6e-34 115.8 4.6 1e-33 115.5 4.6 1.1 1 0 0 1 1 1 1 S25 ribosomal protein Fe_dep_repress PF01325.19 PRP79377.1 - 0.0011 19.2 0.1 0.0018 18.5 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_24 PF13412.6 PRP79377.1 - 0.014 14.9 0.4 0.021 14.4 0.4 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.19 PRP79377.1 - 0.016 15.1 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF3987 PF13148.6 PRP79377.1 - 0.044 12.8 0.1 0.048 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Complex1_LYR PF05347.15 PRP79378.1 - 7.4e-08 32.3 0.5 1.5e-07 31.4 0.1 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Laminin_EGF PF00053.24 PRP79380.1 - 0.0078 16.3 7.5 0.028 14.5 7.5 2.0 1 0 0 1 1 1 1 Laminin EGF domain SOG2 PF10428.9 PRP79380.1 - 0.025 13.8 23.8 0.044 13.0 23.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 PRP79380.1 - 5 5.6 18.8 12 4.3 18.8 1.6 1 0 0 1 1 1 0 Macoilin family EGF_2 PF07974.13 PRP79380.1 - 5.9 7.4 19.3 0.77 10.2 13.9 2.4 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 PRP79381.1 - 0.047 13.8 11.8 0.14 12.3 11.8 1.8 1 0 0 1 1 1 0 Laminin EGF domain TMEM223 PF14640.6 PRP79381.1 - 0.25 11.5 1.9 0.91 9.7 0.4 2.5 1 1 1 2 2 2 0 Transmembrane protein 223 SOG2 PF10428.9 PRP79381.1 - 1.3 8.1 14.2 2.1 7.5 14.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein EGF_2 PF07974.13 PRP79381.1 - 5.4 7.5 24.5 0.22 11.9 18.0 2.2 2 0 0 2 2 2 0 EGF-like domain MGC-24 PF05283.11 PRP79381.1 - 8.4 6.8 23.7 0.81 10.1 7.4 2.8 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CAP PF00188.26 PRP79382.1 - 6.2e-20 72.3 6.6 6.2e-20 72.3 6.6 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family PT PF04886.12 PRP79382.1 - 0.0075 15.8 6.1 0.0075 15.8 6.1 4.9 2 1 1 3 3 3 2 PT repeat LSM14 PF12701.7 PRP79383.1 - 1.7e-13 50.4 0.0 4.4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 PRP79383.1 - 4.1e-07 30.8 7.6 2.7e-05 25.0 0.1 4.7 5 1 1 6 6 6 2 FDF domain Macoilin PF09726.9 PRP79383.1 - 6 5.3 9.2 1.2 7.6 5.7 1.7 1 1 0 1 1 1 0 Macoilin family CENP-B_dimeris PF09026.10 PRP79384.1 - 0.27 11.6 0.2 0.4 11.1 0.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PKD PF00801.20 PRP79385.1 - 0.052 13.4 0.3 1 9.3 0.0 2.8 3 0 0 3 3 3 0 PKD domain ASH PF15780.5 PRP79387.1 - 3.8e-44 148.9 14.1 8.4e-08 32.3 0.2 10.5 11 0 0 11 11 11 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 PRP79387.1 - 9.2e-15 54.4 2.7 0.33 10.8 0.0 10.4 11 0 0 11 11 11 2 MSP (Major sperm protein) domain PapD-like PF14874.6 PRP79387.1 - 3.3e-13 49.6 7.2 0.12 12.6 0.1 7.4 6 1 1 7 7 7 4 Flagellar-associated PapD-like DUF1573 PF07610.11 PRP79387.1 - 5e-09 36.1 10.6 0.00038 20.4 0.2 7.6 9 1 0 9 9 9 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 PRP79387.1 - 1.2e-07 31.9 7.9 0.24 11.7 0.0 7.8 9 1 0 9 9 9 2 Transmembrane protein 131-like MYCBPAP PF14646.6 PRP79387.1 - 5.5e-05 22.3 0.6 0.055 12.4 0.1 4.8 4 1 1 5 5 5 1 MYCBP-associated protein family PapD_N PF00345.20 PRP79387.1 - 0.00044 20.1 0.0 0.044 13.7 0.0 3.9 4 0 0 4 4 4 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Transglut_C PF00927.22 PRP79387.1 - 0.034 14.3 1.2 76 3.5 0.0 5.3 7 0 0 7 7 7 0 Transglutaminase family, C-terminal ig like domain fn3_5 PF06280.12 PRP79387.1 - 0.035 14.8 8.7 7.6 7.3 0.0 6.4 6 1 1 7 7 7 0 Fn3-like domain Calycin_like PF13944.6 PRP79387.1 - 3.2 8.1 5.0 5.2 7.4 0.5 3.6 5 0 0 5 5 5 0 Calycin-like beta-barrel domain ERG4_ERG24 PF01222.17 PRP79388.1 - 9.5e-134 446.4 23.3 7.4e-133 443.4 23.3 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family VirB3 PF05101.13 PRP79388.1 - 1.1 9.6 0.0 1.1 9.6 0.0 4.0 4 1 1 5 5 5 0 Type IV secretory pathway, VirB3-like protein DUF5381 PF17353.2 PRP79388.1 - 1.7 8.4 4.6 4.4 7.0 4.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5381) Pept_tRNA_hydro PF01195.19 PRP79389.1 - 9.4e-52 175.4 0.0 1.6e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PPP4R2 PF09184.11 PRP79389.1 - 0.024 14.3 16.8 0.03 13.9 16.8 1.1 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.12 PRP79389.1 - 0.34 9.8 11.9 0.47 9.4 11.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_23 PF13476.6 PRP79389.1 - 0.88 10.0 21.3 1.5 9.3 21.3 1.3 1 0 0 1 1 1 0 AAA domain SpoVR PF04293.13 PRP79389.1 - 1.4 7.5 13.7 2.3 6.8 13.7 1.4 1 0 0 1 1 1 0 SpoVR like protein AAA_11 PF13086.6 PRP79389.1 - 2.3 7.9 12.5 3.2 7.5 12.5 1.2 1 0 0 1 1 1 0 AAA domain DUF3959 PF13105.6 PRP79389.1 - 3.7 7.0 12.0 5.3 6.5 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Presenilin PF01080.17 PRP79389.1 - 4.2 6.0 16.6 5.3 5.7 16.6 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 PRP79389.1 - 4.5 5.3 14.4 5.3 5.0 14.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 PRP79389.1 - 4.7 6.1 15.2 6 5.8 15.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 PRP79389.1 - 6.7 6.0 21.0 9.5 5.5 21.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PA26 PF04636.13 PRP79389.1 - 7.5 5.4 11.8 9.2 5.1 11.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Zip PF02535.22 PRP79389.1 - 8.3 5.5 11.5 11 5.1 11.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 PRP79389.1 - 8.3 6.1 21.5 11 5.7 21.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 PRP79389.1 - 8.7 4.1 14.2 11 3.8 14.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.17 PRP79389.1 - 8.9 6.4 10.0 14 5.7 10.0 1.3 1 0 0 1 1 1 0 DDHD domain ABC_tran PF00005.27 PRP79390.1 - 9e-24 84.5 0.0 1.4e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 PRP79390.1 - 2.8e-09 36.7 17.6 2.8e-09 36.7 17.6 3.9 3 2 0 3 3 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 PRP79390.1 - 0.0016 17.7 9.4 0.0016 17.7 9.4 2.9 3 0 0 3 3 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP79390.1 - 0.0035 17.2 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 PRP79390.1 - 0.005 16.4 0.1 0.016 14.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP79390.1 - 0.0052 17.2 0.0 0.0084 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PRP79390.1 - 0.0076 16.2 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PRP79390.1 - 0.018 14.5 0.1 0.52 9.7 0.1 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PRP79390.1 - 0.028 14.1 0.4 0.063 13.0 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PRP79390.1 - 0.05 13.9 0.1 0.22 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 PRP79390.1 - 0.068 12.9 0.3 0.11 12.2 0.3 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PRP79390.1 - 0.071 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 PRP79390.1 - 0.15 11.4 0.5 0.26 10.6 0.5 1.2 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 PRP79390.1 - 0.16 12.1 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PRP79390.1 - 0.17 12.4 0.0 0.35 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 PRP79390.1 - 0.25 11.1 0.3 0.69 9.6 0.6 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 PRP79391.1 - 3.7e-30 105.5 0.1 9.2e-30 104.3 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP79391.1 - 9.3e-25 87.5 0.0 1.9e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HATPase_c PF02518.26 PRP79391.1 - 1.4e-24 86.7 0.1 3.8e-24 85.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP79391.1 - 3e-22 78.9 0.7 9.6e-22 77.3 0.7 2.0 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase_Tyr PF07714.17 PRP79391.1 - 5.3e-18 65.2 0.0 1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HisKA PF00512.25 PRP79391.1 - 5.4e-07 29.6 1.2 2.4e-06 27.5 0.2 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP79391.1 - 4.4e-06 26.6 0.1 1.1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 PRP79391.1 - 7.7e-06 26.6 0.0 4.7e-05 24.0 0.0 2.4 3 0 0 3 3 2 1 GAF domain GAF_2 PF13185.6 PRP79391.1 - 7.6e-05 23.0 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.6 PRP79391.1 - 0.00092 19.5 0.3 0.0076 16.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 PRP79391.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Kinase-like PF14531.6 PRP79391.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NB-ARC PF00931.22 PRP79391.1 - 0.063 12.4 0.0 0.47 9.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 PRP79391.1 - 0.081 12.8 0.2 0.69 9.8 0.2 2.4 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 PRP79391.1 - 0.12 12.9 0.9 0.51 10.8 0.0 2.5 3 0 0 3 3 2 0 ABC transporter Methyltransf_25 PF13649.6 PRP79392.1 - 4.3e-05 24.1 0.0 0.00047 20.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP79392.1 - 0.0002 21.9 0.0 0.00035 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP79392.1 - 0.00042 20.1 0.1 0.0028 17.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP79392.1 - 0.031 15.0 0.0 0.2 12.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 PRP79392.1 - 0.054 12.8 0.3 0.32 10.3 0.3 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pkinase PF00069.25 PRP79393.1 - 6.9e-52 176.4 0.0 8e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79393.1 - 1.7e-24 86.6 0.0 2.1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP79393.1 - 1.1e-05 24.6 0.2 9.1e-05 21.6 0.2 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP79393.1 - 0.0033 16.2 0.1 0.0052 15.6 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP79393.1 - 0.0044 16.4 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP79393.1 - 0.0093 15.9 0.2 0.022 14.7 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP79393.1 - 0.033 13.5 0.0 0.14 11.4 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 PRP79393.1 - 0.18 11.3 1.4 0.71 9.4 1.4 2.0 1 1 0 1 1 1 0 Choline/ethanolamine kinase MT-A70 PF05063.14 PRP79394.1 - 5e-27 94.9 0.0 7.8e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Got1 PF04178.12 PRP79395.1 - 9.2e-34 116.3 18.9 9.2e-34 116.3 18.9 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family DUF4064 PF13273.6 PRP79395.1 - 3.1 8.1 15.7 8 6.8 15.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) LCAT PF02450.15 PRP79396.1 - 5.2e-05 22.6 0.0 9.9e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 PRP79396.1 - 0.00029 20.6 0.0 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein FOXP-CC PF16159.5 PRP79396.1 - 0.0079 16.8 0.4 0.024 15.2 0.4 1.8 1 0 0 1 1 1 1 FOXP coiled-coil domain Abhydrolase_6 PF12697.7 PRP79396.1 - 0.043 14.4 0.0 0.081 13.5 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP79396.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF4854 PF16146.5 PRP79396.1 - 0.16 12.4 0.4 0.73 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Pkinase PF00069.25 PRP79397.1 - 1.8e-62 211.1 0.0 5.4e-62 209.6 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79397.1 - 1.3e-42 145.9 0.0 4.1e-42 144.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 PRP79397.1 - 0.0041 16.7 0.0 0.0041 16.7 0.0 3.8 5 0 0 5 5 5 1 PhoP regulatory network protein YrbL APH PF01636.23 PRP79397.1 - 0.24 11.3 3.6 0.32 10.9 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family C2 PF00168.30 PRP79398.1 - 3.4e-05 24.1 0.0 5.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 C2 domain YjcB PF15940.5 PRP79399.1 - 0.004 17.3 4.0 0.81 9.9 0.6 2.5 2 0 0 2 2 2 2 Family of unknown function DHHC PF01529.20 PRP79399.1 - 0.078 13.1 0.4 0.078 13.1 0.4 3.2 2 1 1 3 3 3 0 DHHC palmitoyltransferase EGF_2 PF07974.13 PRP79399.1 - 0.67 10.4 4.1 1.3 9.5 4.1 1.4 1 0 0 1 1 1 0 EGF-like domain Xpo1 PF08389.12 PRP79401.1 - 0.0059 16.7 0.5 0.76 9.8 0.0 3.9 4 0 0 4 4 4 1 Exportin 1-like protein BPL_N PF09825.9 PRP79402.1 - 2.7e-17 62.9 0.0 5.2e-11 42.2 0.0 2.0 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal GATase PF00117.28 PRP79402.1 - 0.004 16.9 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 PRP79402.1 - 0.0045 16.6 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 PRP79402.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Stealth_CR2 PF11380.8 PRP79403.1 - 7.9e-26 90.4 0.9 7.4e-24 84.0 0.9 2.6 1 1 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 PRP79403.1 - 1.3e-10 41.0 0.4 2.1e-10 40.3 0.4 1.4 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Ifi-6-16 PF06140.13 PRP79403.1 - 0.00024 20.9 25.0 0.00034 20.5 23.8 1.9 1 1 1 2 2 2 1 Interferon-induced 6-16 family IQ PF00612.27 PRP79404.1 - 0.029 14.1 0.3 0.07 13.0 0.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Mito_carr PF00153.27 PRP79405.1 - 4.4e-71 234.9 3.4 3e-25 88.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.11 PRP79405.1 - 0.043 14.0 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Uperin family Amino_oxidase PF01593.24 PRP79406.1 - 3.1e-95 320.1 0.0 5e-95 319.4 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP79406.1 - 3e-14 53.0 0.4 5.9e-14 52.1 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 PRP79406.1 - 2e-12 47.3 0.0 6.6e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain SRI PF08236.11 PRP79406.1 - 6.4e-09 35.9 6.9 2.2e-08 34.1 6.9 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Pyr_redox_2 PF07992.14 PRP79406.1 - 5.6e-08 32.4 0.1 5.1e-06 25.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP79406.1 - 8.9e-06 26.2 0.6 4.3e-05 24.0 0.4 2.3 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP79406.1 - 1e-05 24.9 0.6 2.7e-05 23.4 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 PRP79406.1 - 3.9e-05 23.4 2.4 3.9e-05 23.4 2.4 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PRP79406.1 - 4.2e-05 22.9 0.4 0.00015 21.1 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PRP79406.1 - 7.3e-05 21.6 0.1 7.3e-05 21.6 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 PRP79406.1 - 9.1e-05 21.7 1.2 0.001 18.2 0.4 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 PRP79406.1 - 0.00036 20.0 1.8 0.00036 20.0 1.8 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 PRP79406.1 - 0.0011 18.3 0.0 0.0037 16.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 PRP79406.1 - 0.0014 17.9 0.9 0.0036 16.6 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 PRP79406.1 - 0.0038 16.5 0.0 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase YjeF_N PF03853.15 PRP79406.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 YjeF-related protein N-terminus Lycopene_cycl PF05834.12 PRP79406.1 - 0.12 11.4 1.2 0.17 10.9 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 PRP79406.1 - 0.55 9.9 1.9 4.4 6.9 0.8 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GMC_oxred_N PF00732.19 PRP79408.1 - 4.7e-37 128.0 2.4 3.2e-19 69.4 0.3 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP79408.1 - 6.8e-10 39.6 0.0 1.9e-09 38.2 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PRP79408.1 - 2.9e-05 24.2 0.2 0.00012 22.2 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PRP79408.1 - 0.00028 20.1 0.1 0.00048 19.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PRP79408.1 - 0.00088 18.6 0.4 0.0071 15.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP79408.1 - 0.0015 18.2 0.2 0.005 16.5 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PRP79408.1 - 0.016 14.3 0.2 0.035 13.2 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain SecG PF03840.14 PRP79408.1 - 0.034 14.2 0.1 0.11 12.6 0.1 1.9 1 0 0 1 1 1 0 Preprotein translocase SecG subunit TrkA_N PF02254.18 PRP79408.1 - 0.038 14.3 0.0 3.3 8.0 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain ApbA PF02558.16 PRP79408.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 PRP79408.1 - 0.048 12.9 0.4 1.3 8.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP79408.1 - 0.1 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 PRP79408.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family SH2 PF00017.24 PRP79409.1 - 1.8e-05 24.7 0.0 2.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 SH2 domain DUF4278 PF14105.6 PRP79410.1 - 0.077 13.4 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4278) Cytochrom_B561 PF03188.16 PRP79411.1 - 1.7e-06 28.2 5.4 0.013 15.6 0.9 2.9 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 Cation_ATPase_C PF00689.21 PRP79411.1 - 0.013 15.2 1.9 0.014 15.1 0.3 1.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF4079 PF13301.6 PRP79411.1 - 0.015 15.4 3.2 1.1 9.4 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Sulfate_transp PF00916.20 PRP79411.1 - 0.034 12.9 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Sulfate permease family Virul_fac_BrkB PF03631.15 PRP79411.1 - 0.044 13.4 0.3 0.044 13.4 0.3 2.3 1 1 1 2 2 2 0 Virulence factor BrkB DUF4231 PF14015.6 PRP79411.1 - 0.05 14.1 1.0 2 8.9 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Phage_holin_3_6 PF07332.11 PRP79411.1 - 0.067 13.2 10.7 3.2 7.8 0.0 3.2 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SLAC1 PF03595.17 PRP79411.1 - 0.068 12.4 9.3 0.021 14.1 4.5 1.9 1 1 0 1 1 1 0 Voltage-dependent anion channel HlyIII PF03006.20 PRP79411.1 - 0.074 12.8 2.6 0.28 10.9 2.6 1.9 1 1 0 1 1 1 0 Haemolysin-III related Ceramidase PF05875.12 PRP79411.1 - 0.092 12.2 3.7 1.1 8.6 0.1 2.5 2 1 0 2 2 2 0 Ceramidase DUF2231 PF09990.9 PRP79411.1 - 0.19 12.2 9.6 0.079 13.4 5.3 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) Wzy_C_2 PF11846.8 PRP79411.1 - 0.22 11.4 1.1 3.8 7.4 0.4 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF3169 PF11368.8 PRP79411.1 - 0.26 10.8 4.2 8.7 5.8 4.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) SAYSvFN PF10260.9 PRP79412.1 - 5.6e-26 90.3 1.6 8.9e-26 89.6 1.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) Guanylate_cyc PF00211.20 PRP79413.1 - 2.2e-19 69.8 0.1 1.9e-08 34.1 0.1 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 PRP79413.1 - 1.1e-15 58.5 0.0 6.2e-14 52.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF2791 PF10923.8 PRP79413.1 - 1.4e-05 24.1 0.1 2.4e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) NACHT PF05729.12 PRP79413.1 - 0.0024 17.8 0.2 2.9 7.8 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 PRP79413.1 - 0.0051 17.1 0.0 0.022 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain HSM3_N PF18795.1 PRP79413.1 - 0.009 15.5 0.2 0.027 13.9 0.2 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain DUF4372 PF14294.6 PRP79413.1 - 0.13 12.5 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) Pro-kuma_activ PF09286.11 PRP79414.1 - 6e-22 78.5 1.3 1.1e-21 77.6 1.3 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain ADAM_CR PF08516.12 PRP79414.1 - 1.4 9.4 4.2 12 6.3 2.1 2.7 3 0 0 3 3 3 0 ADAM cysteine-rich PIP5K PF01504.18 PRP79416.1 - 6.4e-80 268.3 2.0 1.2e-79 267.4 2.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ras PF00071.22 PRP79416.1 - 5.8e-11 42.3 0.2 1.1e-10 41.4 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79416.1 - 2.6e-08 34.1 0.2 5.7e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP79416.1 - 7.8e-05 22.2 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 PRP79416.1 - 0.04 13.6 0.1 0.097 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PRP79416.1 - 0.088 13.3 0.5 0.48 10.9 0.5 2.4 1 1 0 1 1 1 0 ABC transporter DUF5113 PF17140.4 PRP79416.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) MMR_HSR1 PF01926.23 PRP79416.1 - 0.15 12.1 0.1 0.47 10.5 0.1 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase CENP-M PF11111.8 PRP79416.1 - 0.16 11.2 0.3 0.79 8.9 0.0 2.0 2 0 0 2 2 2 0 Centromere protein M (CENP-M) L51_S25_CI-B8 PF05047.16 PRP79418.1 - 5.7e-08 32.6 0.0 2.4e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CBM_26 PF16824.5 PRP79418.1 - 0.081 13.1 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 C-terminal carbohydrate-binding module LRR_8 PF13855.6 PRP79419.1 - 2.6e-58 193.6 109.2 4.6e-07 29.5 0.6 15.9 10 4 6 17 17 17 16 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP79419.1 - 2.3e-54 184.4 0.1 4.9e-54 183.3 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP79419.1 - 6.6e-45 150.3 124.2 5.6e-05 23.4 0.3 21.6 14 5 14 28 28 27 22 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP79419.1 - 3.6e-38 131.4 0.0 5.2e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 PRP79419.1 - 4.5e-09 35.6 92.6 0.41 10.8 0.1 24.4 27 0 0 27 27 27 6 Leucine Rich repeat LRR_1 PF00560.33 PRP79419.1 - 5.9e-05 23.1 112.2 1.6 9.5 0.1 26.4 30 2 0 30 30 27 6 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP79419.1 - 0.00037 20.7 0.5 0.00037 20.7 0.5 2.1 2 0 0 2 2 1 1 Leucine rich repeat N-terminal domain Kdo PF06293.14 PRP79419.1 - 0.027 13.8 0.2 0.061 12.7 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Orf78 PF06024.12 PRP79419.1 - 0.073 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 PRP79419.1 - 0.079 12.9 0.3 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 TMEM154 protein family TMEM132D_C PF15706.5 PRP79419.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SKG6 PF08693.10 PRP79419.1 - 0.57 9.6 6.0 1.3 8.5 6.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CE2_N PF17996.1 PRP79420.1 - 1.9e-18 66.4 0.0 8.1e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 PRP79420.1 - 1.1e-07 32.4 1.1 7.2e-07 29.8 0.1 2.1 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CDC48_2 PF02933.17 PRP79420.1 - 0.00038 20.2 0.5 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Cell division protein 48 (CDC48), domain 2 PMP22_Claudin PF00822.20 PRP79420.1 - 0.045 13.6 0.5 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family EMC3_TMCO1 PF01956.16 PRP79423.1 - 4.7e-53 179.4 3.5 7e-53 178.8 3.5 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF1664 PF07889.12 PRP79424.1 - 1.2 9.2 9.6 1.1 9.3 7.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Nucleoporin_N PF08801.11 PRP79425.1 - 6.7e-37 127.3 0.0 1.2e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 PRP79425.1 - 5.1e-10 38.7 3.4 9e-10 37.9 3.4 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal ANAPC3 PF12895.7 PRP79425.1 - 0.23 11.7 2.5 7.1 6.9 0.4 3.8 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Cyclin_N PF00134.23 PRP79426.1 - 1.2e-17 63.8 0.1 2.1e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP79426.1 - 1.1e-16 61.0 0.1 6.2e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain Use1 PF09753.9 PRP79429.1 - 8.8e-28 97.7 11.9 1.2e-27 97.2 11.9 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Dsh_C PF12316.8 PRP79429.1 - 0.29 11.5 1.7 0.39 11.1 0.1 1.8 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal FAM60A PF15396.6 PRP79429.1 - 0.66 9.9 7.0 0.41 10.6 0.2 2.0 1 1 1 2 2 2 0 Protein Family FAM60A Zip PF02535.22 PRP79430.1 - 0.62 9.2 2.7 0.62 9.2 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AIF_C PF14721.6 PRP79430.1 - 2.1 8.7 5.9 3.9 7.8 5.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Sortilin-Vps10 PF15902.5 PRP79432.1 - 4.4e-69 233.4 6.0 6.7e-69 232.8 6.0 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PRP79432.1 - 1.6e-27 96.9 5.9 2.6e-27 96.2 5.9 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PSII_BNR PF14870.6 PRP79432.1 - 0.00062 19.1 2.2 0.0042 16.4 2.2 2.3 1 1 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 PRP79432.1 - 0.024 14.6 27.7 5.2 7.5 0.9 7.4 7 0 0 7 7 7 0 BNR/Asp-box repeat DnaJ_CXXCXGXG PF00684.19 PRP79433.1 - 0.12 12.7 20.6 3.2 8.2 12.7 2.7 1 1 2 3 3 3 0 DnaJ central domain Chromo PF00385.24 PRP79434.1 - 3.5e-06 26.8 1.9 5.9e-06 26.1 1.9 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Trypan_PARP PF05887.11 PRP79434.1 - 0.0048 16.9 3.5 0.0075 16.2 3.5 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SF3a60_bindingd PF12108.8 PRP79434.1 - 0.008 16.0 1.2 0.017 15.0 1.2 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Tudor-knot PF11717.8 PRP79434.1 - 0.016 15.1 1.3 0.04 13.8 1.3 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain MLVIN_C PF18697.1 PRP79434.1 - 0.018 15.1 0.1 0.046 13.8 0.1 1.7 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RT_RNaseH PF17917.1 PRP79435.1 - 1.7e-36 124.7 0.0 4.5e-36 123.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 PRP79435.1 - 3.6e-29 101.9 0.1 6e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PRP79435.1 - 3.9e-29 100.6 0.0 8.1e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP79435.1 - 5.6e-21 74.4 0.1 1.2e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PRP79435.1 - 0.00052 20.2 0.0 0.0023 18.1 0.0 2.2 2 0 0 2 2 2 1 H2C2 zinc finger DDE_Tnp_4 PF13359.6 PRP79436.1 - 2.1e-23 82.7 0.0 2.8e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP79436.1 - 8.2e-08 32.2 0.4 3.8e-07 30.0 0.4 1.9 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 PRP79436.1 - 0.00027 20.6 0.0 0.00069 19.3 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein DUF2405 PF10293.9 PRP79436.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Pkinase_Tyr PF07714.17 PRP79437.1 - 1.8e-44 152.0 0.1 2e-43 148.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79437.1 - 1.5e-40 139.2 0.0 3.7e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RA PF00788.23 PRP79437.1 - 0.00023 21.7 5.6 0.018 15.7 0.4 3.7 3 1 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Haspin_kinase PF12330.8 PRP79437.1 - 0.00064 18.8 0.5 0.0036 16.3 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 PRP79437.1 - 0.0058 16.0 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP79437.1 - 0.0089 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 PRP79439.1 - 1e-35 122.1 0.0 6.1e-11 42.8 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP79439.1 - 1.1e-28 98.8 0.2 0.014 15.7 0.0 8.8 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP79439.1 - 4.8e-28 97.2 0.1 0.00021 21.8 0.0 7.2 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP79439.1 - 9.1e-20 68.7 0.0 0.95 10.2 0.0 9.7 9 1 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 PRP79439.1 - 1.6e-14 53.6 0.8 7.5 7.2 0.0 9.4 9 1 0 9 9 9 3 Ankyrin repeat DUF1403 PF07183.11 PRP79439.1 - 0.0068 16.0 5.1 17 4.8 0.1 5.3 1 1 5 7 7 7 1 Protein of unknown function (DUF1403) MSA-2c PF12238.8 PRP79439.1 - 0.075 13.0 0.0 27 4.7 0.0 3.1 3 0 0 3 3 3 0 Merozoite surface antigen 2c DUF4350 PF14258.6 PRP79439.1 - 0.1 13.0 0.4 31 5.1 0.0 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF4350) ADSL_C PF10397.9 PRP79439.1 - 7.4 7.2 8.1 2.7e+02 2.2 0.1 5.2 1 1 6 7 7 7 0 Adenylosuccinate lyase C-terminus VapB_antitoxin PF09957.9 PRP79439.1 - 8.6 6.4 7.5 38 4.3 0.1 4.6 6 0 0 6 6 6 0 Bacterial antitoxin of type II TA system, VapB HIF-1 PF11413.8 PRP79440.1 - 0.099 12.1 0.5 0.16 11.4 0.5 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 NPR3 PF03666.13 PRP79441.1 - 8.8e-41 140.2 17.7 5.4e-23 81.5 2.0 3.4 2 1 2 4 4 4 3 Nitrogen Permease regulator of amino acid transport activity 3 Cytochrom_B561 PF03188.16 PRP79441.1 - 8.4e-10 38.9 8.8 2.3e-09 37.5 8.8 1.8 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 NPR2 PF06218.11 PRP79441.1 - 0.00034 19.5 0.0 0.0035 16.1 0.0 2.2 1 1 0 1 1 1 1 Nitrogen permease regulator 2 DUF4079 PF13301.6 PRP79441.1 - 0.051 13.7 13.8 0.1 12.7 2.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Rootletin PF15035.6 PRP79441.1 - 0.059 13.4 1.3 0.062 13.3 0.2 1.6 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion MFS_1 PF07690.16 PRP79443.1 - 2.3e-57 194.5 33.3 9.3e-49 166.2 4.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 PRP79443.1 - 3.9e-15 55.3 18.2 5.2e-09 35.1 3.5 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 PRP79443.1 - 1.3e-14 54.0 6.4 1.3e-14 54.0 6.4 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 PRP79443.1 - 0.0002 19.9 2.5 0.00044 18.8 2.5 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2207 PF09972.9 PRP79443.1 - 0.0051 15.6 0.1 0.0051 15.6 0.1 4.1 2 2 0 3 3 3 1 Predicted membrane protein (DUF2207) Tim54 PF11711.8 PRP79443.1 - 0.052 12.3 1.4 0.078 11.7 1.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GNAT_acetyltr_2 PF13718.6 PRP79443.1 - 0.22 10.9 1.2 0.43 9.9 1.2 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Ferlin_C PF16165.5 PRP79443.1 - 3.9 7.4 5.2 6.7 6.6 0.3 2.6 2 0 0 2 2 2 0 Ferlin C-terminus G0-G1_switch_2 PF15103.6 PRP79443.1 - 4 7.9 5.3 11 6.5 5.3 1.7 1 0 0 1 1 1 0 G0/G1 switch protein 2 Ferric_reduct PF01794.19 PRP79444.1 - 0.033 14.3 0.1 0.041 14.0 0.1 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component EBA-175_VI PF11556.8 PRP79444.1 - 0.084 13.2 1.0 0.25 11.7 1.0 1.8 1 1 0 1 1 1 0 Erythrocyte binding antigen 175 Voltage_CLC PF00654.20 PRP79445.1 - 1.2e-72 245.1 24.6 1.2e-72 245.1 24.6 1.5 1 1 0 1 1 1 1 Voltage gated chloride channel PRA1 PF03208.19 PRP79445.1 - 0.037 13.7 0.4 0.037 13.7 0.4 2.9 3 1 0 3 3 3 0 PRA1 family protein AlaE PF06610.13 PRP79445.1 - 0.045 13.8 0.3 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 L-alanine exporter AzlD PF05437.12 PRP79445.1 - 0.13 12.5 8.7 3.3 7.9 0.2 4.2 4 1 0 4 4 4 0 Branched-chain amino acid transport protein (AzlD) Pex24p PF06398.11 PRP79451.1 - 0.87 8.5 2.7 2.3 7.1 2.7 1.7 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin COesterase PF00135.28 PRP79453.1 - 0.00046 19.2 0.1 0.00067 18.6 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF2686 PF10887.8 PRP79454.1 - 0.0085 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2686) DUF3586 PF12131.8 PRP79455.1 - 0.051 13.8 0.1 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3586) adh_short PF00106.25 PRP79457.1 - 0.00018 21.0 0.0 0.029 13.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase NMD3 PF04981.13 PRP79459.1 - 0.00018 21.1 0.2 0.00034 20.2 0.2 1.4 1 0 0 1 1 1 1 NMD3 family WAK_assoc PF14380.6 PRP79459.1 - 0.55 11.0 0.1 0.55 11.0 0.1 3.0 3 0 0 3 3 3 0 Wall-associated receptor kinase C-terminal SAP PF02037.27 PRP79461.1 - 0.00044 19.9 0.1 0.00081 19.1 0.1 1.4 1 0 0 1 1 1 1 SAP domain Integrase_H2C2 PF17921.1 PRP79462.1 - 1.2e-20 73.3 0.9 1.2e-20 73.3 0.9 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain zf-H2C2 PF09337.10 PRP79462.1 - 1.7e-07 31.3 0.6 3.3e-07 30.4 0.1 1.8 2 0 0 2 2 2 1 H2C2 zinc finger RVT_1 PF00078.27 PRP79463.1 - 6.4e-46 156.6 0.2 1.8e-45 155.2 0.2 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 PRP79463.1 - 1.4e-11 44.7 0.0 5.3e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 PRP79463.1 - 0.098 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family YqgF PF14639.6 PRP79463.1 - 0.33 10.7 2.7 14 5.5 0.0 3.5 3 0 0 3 3 3 0 Holliday-junction resolvase-like of SPT6 UL42 PF17638.2 PRP79464.1 - 0.024 14.6 1.2 0.043 13.8 1.2 1.4 1 0 0 1 1 1 0 HCMV UL42 zf-RVT PF13966.6 PRP79464.1 - 0.029 15.1 0.2 0.047 14.4 0.2 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Otopetrin PF03189.13 PRP79465.1 - 0.0018 17.2 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Otopetrin Consortin_C PF15281.6 PRP79465.1 - 0.051 13.6 0.8 0.33 11.0 0.1 2.4 2 0 0 2 2 2 0 Consortin C-terminus Radial_spoke PF04712.12 PRP79465.1 - 0.14 11.1 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein NCD3G PF07562.14 PRP79465.1 - 7.6 6.6 13.7 0.029 14.3 1.4 2.7 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Ctr PF04145.15 PRP79468.1 - 4.8e-17 62.9 6.5 4.8e-17 62.9 6.5 3.0 2 1 0 2 2 2 1 Ctr copper transporter family ADK PF00406.22 PRP79468.1 - 1.5e-07 31.6 0.4 6.2e-07 29.6 0.4 2.0 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PRP79468.1 - 2.6e-05 24.7 0.1 0.00011 22.6 0.1 2.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP79468.1 - 0.14 12.7 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF5394 PF17372.2 PRP79468.1 - 0.21 11.1 1.2 0.37 10.3 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5394) PDCD2_C PF04194.13 PRP79469.1 - 1.2e-27 97.2 25.0 1.6e-26 93.4 20.1 3.3 1 1 1 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PhnA_Zn_Ribbon PF08274.12 PRP79469.1 - 0.00098 19.0 1.7 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 PhnA Zinc-Ribbon Zn-ribbon_8 PF09723.10 PRP79469.1 - 0.012 15.7 1.0 3.8 7.7 0.1 3.0 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 PRP79469.1 - 0.12 12.4 1.3 2.2 8.3 0.0 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-RRN7 PF11781.8 PRP79469.1 - 0.22 11.2 2.1 5.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Lar_restr_allev PF14354.6 PRP79469.1 - 3.3 8.1 8.7 16 6.0 0.0 3.2 3 1 0 3 3 3 0 Restriction alleviation protein Lar YdjO PF14169.6 PRP79469.1 - 4.7 7.0 8.3 0.85 9.4 0.3 3.1 3 0 0 3 3 3 0 Cold-inducible protein YdjO TFIIS_C PF01096.18 PRP79469.1 - 7.2 6.6 6.9 3 7.8 0.0 3.3 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) Serine_rich PF08824.10 PRP79470.1 - 0.00053 20.0 2.3 0.00053 20.0 2.3 2.7 2 1 0 2 2 2 1 Serine rich protein interaction domain Mobilization_B PF17511.2 PRP79470.1 - 0.0069 16.7 1.7 0.015 15.7 1.7 1.4 1 0 0 1 1 1 1 Mobilization protein B RecO_C PF02565.15 PRP79470.1 - 0.017 15.0 0.4 1 9.1 0.0 2.4 2 0 0 2 2 2 0 Recombination protein O C terminal Peptidase_S49 PF01343.18 PRP79470.1 - 0.042 13.8 1.0 0.094 12.7 1.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 FMN_red PF03358.15 PRP79470.1 - 0.042 13.6 0.1 0.096 12.4 0.1 1.6 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Arg_decarbox_C PF17944.1 PRP79470.1 - 0.17 12.5 0.5 1.8 9.2 0.1 2.8 1 1 1 2 2 2 0 Arginine decarboxylase C-terminal helical extension KapB PF08810.10 PRP79470.1 - 0.17 12.0 3.6 7.4 6.8 1.0 2.9 2 0 0 2 2 2 0 Kinase associated protein B FAA_hydrolase_N PF09298.11 PRP79470.1 - 0.33 11.2 3.0 0.51 10.5 0.7 2.6 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal TipAS PF07739.13 PRP79470.1 - 0.72 10.4 3.4 0.83 10.2 0.6 2.6 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Metallophos PF00149.28 PRP79472.1 - 1.2e-34 120.6 0.2 1.9e-34 119.9 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PRP79472.1 - 0.00019 21.8 0.1 0.0004 20.8 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 PRP79472.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF4574 PF15141.6 PRP79474.1 - 0.062 13.2 0.3 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Cupin_4 PF08007.12 PRP79475.1 - 9.7e-61 206.0 0.0 1.4e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 PRP79475.1 - 1.2e-06 28.4 0.3 0.0002 21.2 0.0 2.8 2 1 0 2 2 2 1 Cupin-like domain DUF5495 PF17599.2 PRP79475.1 - 0.034 14.4 0.1 0.074 13.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5495) HMA PF00403.26 PRP79476.1 - 4.7e-08 33.4 0.2 7.3e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain MerT PF02411.15 PRP79476.1 - 0.0054 16.8 0.5 0.0085 16.1 0.1 1.5 2 0 0 2 2 2 1 MerT mercuric transport protein Pkinase_Tyr PF07714.17 PRP79477.1 - 1.8e-36 125.8 0.0 5.9e-19 68.4 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP79477.1 - 7.8e-19 68.1 0.0 1.2e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain TFIID-31kDa PF02291.15 PRP79477.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Pkinase_Tyr PF07714.17 PRP79478.1 - 3.2e-64 216.7 0.0 5.2e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79478.1 - 1.5e-42 145.8 0.0 2.5e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SKG6 PF08693.10 PRP79478.1 - 0.00077 18.8 2.2 0.0017 17.7 2.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kdo PF06293.14 PRP79478.1 - 0.0017 17.7 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP79478.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DUF5052 PF16475.5 PRP79478.1 - 0.022 14.4 0.2 1.5 8.4 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5052) Ssu72 PF04722.13 PRP79478.1 - 0.095 12.3 0.2 9.2 5.8 0.0 2.6 2 0 0 2 2 2 0 Ssu72-like protein Kinase-like PF14531.6 PRP79478.1 - 0.17 11.1 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pentapeptide_3 PF13576.6 PRP79478.1 - 9.1 6.5 8.6 0.59 10.3 0.2 3.4 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) BCD PF15461.6 PRP79479.1 - 1.2e-42 146.2 10.2 2.4e-42 145.3 10.2 1.5 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase Pkinase_Tyr PF07714.17 PRP79479.1 - 3.6e-16 59.2 0.3 6.4e-16 58.4 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79479.1 - 1.7e-12 47.3 0.1 2.9e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP79479.1 - 1.7e-06 28.5 0.2 1.7e-06 28.5 0.2 2.7 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif ABC_ATPase PF09818.9 PRP79480.1 - 7.5e-167 555.7 0.0 9.8e-167 555.3 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 PRP79480.1 - 0.0035 17.9 3.3 0.02 15.4 3.3 2.2 1 1 0 1 1 1 1 AAA domain DUF4228 PF14009.6 PRP79480.1 - 1.3 9.4 3.6 1.4 9.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) LMBR1 PF04791.16 PRP79481.1 - 5.1e-29 101.6 27.9 1.1e-23 83.9 2.8 3.3 2 1 1 3 3 3 3 LMBR1-like membrane protein G8 PF10162.9 PRP79481.1 - 3.9e-08 33.4 0.1 7.6e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 G8 domain DUF3742 PF12553.8 PRP79481.1 - 0.22 11.6 4.1 0.6 10.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) DUF4716 PF15837.5 PRP79481.1 - 0.25 11.4 0.8 0.66 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) Adipogenin PF15202.6 PRP79481.1 - 0.76 9.9 4.1 2.3 8.3 1.3 3.2 2 0 0 2 2 2 0 Adipogenin m04gp34like PF12216.8 PRP79481.1 - 0.92 9.0 3.6 4.3 6.8 0.6 2.6 2 0 0 2 2 2 0 Immune evasion protein DUF2207 PF09972.9 PRP79481.1 - 1.4 7.6 33.8 1.4 7.6 1.5 4.7 2 2 1 3 3 3 0 Predicted membrane protein (DUF2207) EGF_2 PF07974.13 PRP79482.1 - 0.00064 20.0 11.8 0.0011 19.2 11.8 1.3 1 0 0 1 1 1 1 EGF-like domain DUF2427 PF10348.9 PRP79482.1 - 0.29 11.0 6.6 0.064 13.0 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) EGF PF00008.27 PRP79482.1 - 2.9 8.3 7.1 4.7 7.6 7.1 1.3 1 0 0 1 1 1 0 EGF-like domain GMC_oxred_N PF00732.19 PRP79483.1 - 8.2e-29 100.9 4.5 7.4e-15 55.1 0.3 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP79483.1 - 5.9e-14 52.8 0.4 2.4e-13 50.8 0.4 2.0 1 1 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 PRP79483.1 - 0.00059 19.0 0.2 0.0012 17.9 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 PRP79483.1 - 0.0016 18.1 0.3 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP79483.1 - 0.0019 17.5 0.1 0.0044 16.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PRP79483.1 - 0.013 14.6 0.6 2.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PRP79483.1 - 0.016 14.4 0.1 0.06 12.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP79483.1 - 0.052 13.8 1.3 0.11 12.8 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PRP79483.1 - 0.079 11.7 0.0 0.16 10.6 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein MMtag PF10159.9 PRP79486.1 - 1.6e-12 47.5 7.3 1.6e-12 47.5 7.3 3.4 3 1 0 3 3 3 1 Multiple myeloma tumor-associated Cofilin_ADF PF00241.20 PRP79490.1 - 0.04 13.7 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein DUF1996 PF09362.10 PRP79491.1 - 1.1e-72 244.8 3.6 1.9e-72 244.0 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FRG1 PF06229.12 PRP79491.1 - 0.017 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 FRG1-like domain GATA PF00320.27 PRP79492.1 - 1.3e-11 43.9 1.1 1.3e-11 43.9 1.1 2.7 3 1 0 3 3 3 1 GATA zinc finger PHD PF00628.29 PRP79492.1 - 0.0045 16.9 12.1 0.0045 16.9 12.1 2.9 2 1 1 3 3 3 1 PHD-finger zf-RING_7 PF02591.15 PRP79492.1 - 1.8 8.8 7.3 28 5.0 0.1 4.0 2 1 0 2 2 2 0 C4-type zinc ribbon domain XRN_N PF03159.18 PRP79493.1 - 1.8e-32 112.7 0.3 3.9e-17 62.5 0.1 2.4 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PRP79493.1 - 0.0047 15.9 1.7 0.039 12.9 1.7 2.0 1 1 0 1 1 1 1 Xrn1 helical domain Ras PF00071.22 PRP79495.1 - 6.7e-47 159.1 0.0 1.5e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79495.1 - 5.6e-14 52.4 0.0 1.4e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Plant_NMP1 PF06694.11 PRP79495.1 - 0.0022 17.2 0.2 0.0045 16.1 0.2 1.4 1 0 0 1 1 1 1 Plant nuclear matrix protein 1 (NMP1) Arf PF00025.21 PRP79495.1 - 0.0073 15.8 0.0 0.086 12.3 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family TPD52 PF04201.15 PRP79495.1 - 0.056 13.1 0.1 0.056 13.1 0.1 2.8 3 0 0 3 3 3 0 Tumour protein D52 family TH1 PF04858.13 PRP79496.1 - 2.8e-106 356.4 0.0 3.9e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 TH1 protein Zn_clus PF00172.18 PRP79496.1 - 0.00024 21.2 17.6 0.00043 20.3 17.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 PRP79496.1 - 0.042 14.3 0.4 0.19 12.2 0.4 2.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region PAS_8 PF13188.7 PRP79496.1 - 0.05 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 PAS domain DUF4436 PF14494.6 PRP79497.1 - 8.1e-20 71.2 2.4 1e-19 70.8 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Nrap_D2 PF17403.2 PRP79498.1 - 7.3e-36 123.2 1.1 3e-33 114.7 0.4 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 PRP79498.1 - 5.6e-30 104.4 0.7 1.5e-29 103.1 0.4 1.9 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 PRP79498.1 - 2.4e-28 99.2 0.0 5.5e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 RMI2 PF16100.5 PRP79498.1 - 1.7e-25 89.3 0.0 3.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Nrap_D5 PF17406.2 PRP79498.1 - 3.3e-25 88.7 0.1 1.1e-24 87.1 0.0 1.9 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 PRP79498.1 - 1.3e-24 86.7 0.0 3.4e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D6 PF17407.2 PRP79498.1 - 2e-13 50.7 0.2 6.8e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 Nrap protein domain 6 tRNA_anti-codon PF01336.25 PRP79498.1 - 0.14 12.1 0.1 0.36 10.8 0.1 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain SUIM_assoc PF16619.5 PRP79499.1 - 0.029 14.4 0.2 0.029 14.4 0.2 3.6 4 1 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 LMWPc PF01451.21 PRP79500.1 - 2.3e-34 118.8 0.0 2.8e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ank_2 PF12796.7 PRP79501.1 - 2.7e-37 127.2 0.1 3.3e-14 53.2 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79501.1 - 3.6e-34 116.7 0.4 1.7e-08 34.8 0.0 5.9 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP79501.1 - 2.4e-27 94.6 1.9 4.5e-09 36.4 0.0 5.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP79501.1 - 1.8e-26 91.3 2.7 0.0013 19.1 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 PRP79501.1 - 3e-26 88.6 3.7 0.0072 16.7 0.0 8.7 8 1 1 9 9 8 5 Ankyrin repeat ubiquitin PF00240.23 PRP79501.1 - 6.2e-17 61.1 0.1 1.4e-16 60.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP79501.1 - 6.1e-10 38.8 0.1 1.2e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 PRP79501.1 - 0.00097 19.2 0.0 0.0032 17.5 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP79501.1 - 0.0036 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 PRP79501.1 - 0.03 14.4 0.9 7.4 6.7 0.1 2.7 2 1 1 3 3 3 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP79501.1 - 0.058 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain TFIIA PF03153.13 PRP79501.1 - 7.9 6.4 18.8 12 5.8 18.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ras PF00071.22 PRP79502.1 - 5.2e-53 179.0 0.0 7.9e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79502.1 - 2.1e-34 118.3 0.0 6.4e-34 116.7 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP79502.1 - 1e-13 51.2 0.0 1.6e-13 50.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP79502.1 - 5.4e-05 22.8 0.0 0.00014 21.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP79502.1 - 0.00048 20.1 0.1 0.13 12.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP79502.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP79502.1 - 0.002 17.5 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region F-box PF00646.33 PRP79502.1 - 0.024 14.5 0.2 0.046 13.6 0.2 1.5 1 0 0 1 1 1 0 F-box domain ABC_tran PF00005.27 PRP79502.1 - 0.068 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 PRP79502.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit Formin_GBD_N PF18382.1 PRP79506.1 - 0.054 14.0 0.0 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 Formin N-terminal GTPase-binding domain MaoC_dehydrat_N PF13452.6 PRP79507.1 - 0.055 13.6 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase Myosin_head PF00063.21 PRP79508.1 - 3.8e-31 108.0 1.2 9.9e-13 47.2 0.2 3.4 3 1 0 3 3 3 3 Myosin head (motor domain) ZZ PF00569.17 PRP79509.1 - 5.9e-13 48.4 25.2 2.8e-09 36.6 9.0 2.7 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_2 PF03107.16 PRP79509.1 - 0.00032 21.0 27.0 0.001 19.4 6.8 3.5 3 0 0 3 3 3 2 C1 domain DUF35_N PF12172.8 PRP79509.1 - 0.064 13.1 9.2 0.35 10.8 0.5 2.7 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) C1_1 PF00130.22 PRP79509.1 - 0.22 11.5 29.4 0.05 13.5 3.3 4.0 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 PRP79509.1 - 6.3 6.9 22.2 3.5 7.7 5.3 3.5 2 2 0 2 2 2 0 Double zinc ribbon AMPK1_CBM PF16561.5 PRP79510.1 - 2.7e-10 40.3 0.2 4.8e-10 39.5 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Peptidase_S41 PF03572.18 PRP79512.1 - 3.8e-11 42.8 0.1 6.7e-07 29.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase family S41 RIFIN PF02009.16 PRP79512.1 - 3.3e-05 24.0 1.4 6.6e-05 23.0 1.4 1.4 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 PRP79512.1 - 9.2e-05 22.4 1.3 0.00023 21.1 1.3 1.6 1 0 0 1 1 1 1 TMEM154 protein family DAP10 PF07213.11 PRP79512.1 - 0.0075 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 DAP10 membrane protein MGC-24 PF05283.11 PRP79512.1 - 0.023 15.1 3.6 0.068 13.6 3.6 1.8 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4448 PF14610.6 PRP79512.1 - 0.037 13.8 0.4 0.093 12.5 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CPSF100_C PF13299.6 PRP79512.1 - 0.086 13.0 1.1 0.23 11.6 1.1 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Podoplanin PF05808.11 PRP79512.1 - 0.094 12.8 20.0 0.051 13.7 15.9 2.2 1 1 1 2 2 2 0 Podoplanin Mucin PF01456.17 PRP79512.1 - 0.17 11.9 14.8 0.44 10.5 14.8 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Syndecan PF01034.20 PRP79512.1 - 0.29 11.1 1.3 0.42 10.6 0.2 1.9 2 0 0 2 2 2 0 Syndecan domain ABC_tran PF00005.27 PRP79514.1 - 1.9e-47 161.2 0.1 4.6e-23 82.2 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 PRP79514.1 - 3.1e-22 78.4 6.4 3.9e-21 74.9 6.7 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PRP79514.1 - 9e-21 75.0 3.3 3.1e-05 23.9 0.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PRP79514.1 - 9.2e-09 35.1 5.8 0.0066 15.9 0.2 4.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PRP79514.1 - 2.6e-07 30.3 0.0 0.023 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 PRP79514.1 - 1.1e-05 25.9 0.0 0.055 13.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 PRP79514.1 - 1.7e-05 24.7 5.3 0.085 12.6 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 PRP79514.1 - 2.1e-05 25.1 9.4 0.031 14.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.6 PRP79514.1 - 3.4e-05 23.9 0.1 0.57 10.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 PRP79514.1 - 6.8e-05 23.2 0.0 0.083 13.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 PRP79514.1 - 8.2e-05 23.2 0.0 0.6 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PRP79514.1 - 8.6e-05 22.8 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PRP79514.1 - 0.00014 21.8 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PRP79514.1 - 0.00015 22.2 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 PRP79514.1 - 0.00017 21.5 0.6 0.84 9.5 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 PRP79514.1 - 0.00025 21.3 0.2 0.5 10.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 PRP79514.1 - 0.00036 20.6 0.1 0.89 9.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PRP79514.1 - 0.00038 20.2 1.1 0.2 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 PRP79514.1 - 0.00059 19.9 0.0 0.5 10.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 PRP79514.1 - 0.0012 18.6 0.0 0.67 9.7 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 PRP79514.1 - 0.0013 18.8 0.0 0.94 9.5 0.0 3.1 2 1 1 3 3 3 1 Dynamin family NB-ARC PF00931.22 PRP79514.1 - 0.0019 17.4 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_30 PF13604.6 PRP79514.1 - 0.0023 17.7 0.0 0.31 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 PRP79514.1 - 0.0025 17.7 0.0 0.049 13.5 0.0 2.3 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 PRP79514.1 - 0.0029 17.6 0.8 0.14 12.2 0.0 2.8 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 PRP79514.1 - 0.0036 16.6 0.1 0.32 10.2 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.22 PRP79514.1 - 0.0046 17.3 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 PRP79514.1 - 0.0064 16.1 0.0 0.83 9.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 PRP79514.1 - 0.0093 15.0 1.7 0.29 10.1 0.0 3.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 PRP79514.1 - 0.017 14.8 0.7 0.4 10.3 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 PRP79514.1 - 0.018 15.5 0.4 4.3 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 PRP79514.1 - 0.027 14.1 0.5 8.8 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 PRP79514.1 - 0.033 14.1 0.0 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 PRP79514.1 - 0.034 13.9 0.0 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MukB PF04310.12 PRP79514.1 - 0.049 13.4 0.1 2.8 7.7 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal cobW PF02492.19 PRP79514.1 - 0.058 13.0 0.9 1.2 8.7 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 PRP79514.1 - 0.064 12.4 0.0 9.7 5.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Arf PF00025.21 PRP79514.1 - 0.075 12.5 0.1 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF87 PF01935.17 PRP79514.1 - 0.084 13.0 1.4 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 PRP79514.1 - 0.09 12.5 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 PRP79514.1 - 0.1 12.1 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 PRP79514.1 - 0.11 12.7 0.1 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Alg14 PF08660.11 PRP79515.1 - 4.2e-48 163.6 0.0 5.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 PRP79515.1 - 4.6e-21 75.5 0.0 6.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PhoD PF09423.10 PRP79516.1 - 1.5e-13 50.5 0.0 9.7e-12 44.6 0.0 2.4 1 1 0 1 1 1 1 PhoD-like phosphatase AA_permease_2 PF13520.6 PRP79517.1 - 2.8e-46 158.2 37.2 2.8e-46 158.2 37.2 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 PRP79517.1 - 2.2e-30 105.7 33.1 2.2e-30 105.7 33.1 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 PRP79517.1 - 8.6e-10 38.5 2.6 8.6e-10 38.5 2.6 3.9 5 0 0 5 5 5 1 C-terminus of AA_permease Spore_permease PF03845.13 PRP79517.1 - 1.2e-06 27.7 4.9 1.2e-06 27.7 4.9 3.1 4 1 0 4 4 4 1 Spore germination protein FYRC PF05965.14 PRP79518.1 - 5.4e-14 52.1 0.0 4.3e-13 49.2 0.0 2.4 2 0 0 2 2 2 1 F/Y rich C-terminus FYRN PF05964.14 PRP79518.1 - 5e-09 35.9 1.3 9.1e-09 35.0 1.3 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus PPV_E2_N PF00508.17 PRP79519.1 - 0.041 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 E2 (early) protein, N terminal COesterase PF00135.28 PRP79520.1 - 2.6e-114 382.9 0.0 4.2e-114 382.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP79520.1 - 1.9e-08 34.5 0.0 3.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Oxidored_FMN PF00724.20 PRP79521.1 - 1.2e-73 248.3 0.0 1.4e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ras PF00071.22 PRP79522.1 - 2e-50 170.5 0.0 2.5e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79522.1 - 7.4e-21 74.6 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP79522.1 - 3.2e-06 26.7 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP79522.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Lipase_GDSL_2 PF13472.6 PRP79524.1 - 7e-22 78.7 0.0 1e-21 78.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PRP79524.1 - 4e-15 56.3 0.0 5.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MIP PF00230.20 PRP79525.1 - 6.9e-60 202.6 15.8 8.5e-60 202.3 15.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Dsh_C PF12316.8 PRP79525.1 - 0.0076 16.7 1.3 0.011 16.1 1.3 1.2 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal Pam17 PF08566.10 PRP79525.1 - 2.5 7.9 4.9 0.53 10.1 1.1 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Ank PF00023.30 PRP79526.1 - 1.7e-10 40.9 1.1 3.2e-05 24.2 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 PRP79526.1 - 3.3e-10 40.4 0.0 1e-09 38.9 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79526.1 - 7.6e-10 39.1 0.0 0.00016 22.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP79526.1 - 2.6e-09 36.5 0.0 0.002 18.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PRP79526.1 - 7e-08 32.6 0.0 4.5e-05 23.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DNA_repr_REX1B PF14966.6 PRP79526.1 - 0.03 15.0 0.7 0.077 13.7 0.7 1.7 1 0 0 1 1 1 0 DNA repair REX1-B Nup54 PF13874.6 PRP79526.1 - 0.051 13.7 7.8 0.098 12.8 7.8 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HR1 PF02185.16 PRP79526.1 - 0.95 9.6 8.4 0.18 11.9 0.5 2.7 1 1 1 2 2 2 0 Hr1 repeat HAUS6_N PF14661.6 PRP79526.1 - 2.7 7.5 10.1 4.8 6.7 9.9 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HAD_2 PF13419.6 PRP79527.1 - 0.0002 21.5 0.0 0.0027 17.8 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP79527.1 - 0.0057 16.7 0.1 0.028 14.5 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Kinesin PF00225.23 PRP79528.1 - 1.3e-108 362.9 1.6 1.3e-108 362.9 1.6 2.2 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PRP79528.1 - 8.6e-56 188.0 0.2 3.6e-55 186.0 0.1 2.2 1 1 0 1 1 1 1 Microtubule binding TcdB_N PF12918.7 PRP79528.1 - 0.095 13.0 10.9 0.63 10.4 1.2 3.6 2 1 1 3 3 3 0 TcdB toxin N-terminal helical domain DUF4806 PF16064.5 PRP79528.1 - 0.13 12.6 2.9 0.15 12.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) Spc29 PF17082.5 PRP79528.1 - 4.8 6.9 19.1 0.074 12.9 4.2 2.7 1 1 1 2 2 2 0 Spindle Pole Component 29 CAF1 PF04857.20 PRP79529.1 - 1.2e-19 70.6 0.3 5.8e-09 35.6 0.0 2.5 2 1 0 2 2 2 2 CAF1 family ribonuclease EF-hand_1 PF00036.32 PRP79530.1 - 2.6e-16 57.9 8.1 2.8e-06 26.5 0.5 4.9 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PRP79530.1 - 1.4e-15 55.8 1.7 0.00027 20.6 0.2 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 PRP79530.1 - 1.4e-15 57.4 2.4 3.1e-08 34.0 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP79530.1 - 5.3e-12 44.6 7.4 0.0031 16.9 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PRP79530.1 - 4.7e-08 32.8 8.7 0.017 15.0 1.6 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP79530.1 - 0.15 12.4 0.4 9.4 6.6 0.4 2.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region GTP_EFTU PF00009.27 PRP79531.1 - 1.5e-64 217.1 0.2 2.5e-64 216.4 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 PRP79531.1 - 4e-27 94.1 0.0 9.7e-27 92.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PRP79531.1 - 6.1e-23 80.7 0.0 1.2e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PRP79531.1 - 6.1e-11 42.6 0.5 1.6e-10 41.3 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PRP79531.1 - 1.6e-09 37.7 0.0 1.2e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 PRP79531.1 - 5.3e-09 35.9 0.0 1.6e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 PRP79531.1 - 0.00018 21.5 0.0 0.00059 19.9 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PRP79531.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family tRNA_int_endo PF01974.17 PRP79532.1 - 6.3e-14 51.8 0.0 1.6e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Thaumatin PF00314.17 PRP79532.1 - 6.9e-09 35.7 10.2 6.9e-09 35.7 10.2 3.1 2 1 0 2 2 2 1 Thaumatin family Carb_bind PF10645.9 PRP79532.1 - 0.0027 17.9 3.9 0.01 16.0 3.9 2.1 1 0 0 1 1 1 1 Carbohydrate binding Ycf1 PF05758.12 PRP79532.1 - 1.5 6.6 4.4 1.9 6.2 4.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF1682 PF07946.14 PRP79532.1 - 2.4 7.3 11.5 3.3 6.8 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) BTV_NS2 PF04514.12 PRP79532.1 - 4.8 5.9 7.5 10 4.9 7.5 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 LRR_8 PF13855.6 PRP79534.1 - 1.7e-18 66.1 24.8 2.3e-06 27.3 1.4 3.6 1 1 3 4 4 4 4 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP79534.1 - 3.2e-18 66.0 0.2 3.3e-17 62.6 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79534.1 - 3.4e-18 66.0 0.1 5.5e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP79534.1 - 2e-12 47.1 12.8 9.3e-05 22.7 0.8 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP79534.1 - 1.2e-06 28.1 2.6 0.002 17.6 0.3 2.5 1 1 1 2 2 2 2 Leucine-rich repeat Kdo PF06293.14 PRP79534.1 - 3.5e-05 23.3 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_5 PF13306.6 PRP79534.1 - 0.017 15.1 0.1 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PRP79534.1 - 3 8.8 11.0 92 4.2 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat Pyr_redox_2 PF07992.14 PRP79535.1 - 5.6e-45 153.8 0.0 7.1e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 PRP79535.1 - 7.6e-20 71.6 0.4 2.9e-13 50.3 0.1 2.6 1 1 1 2 2 2 2 Apoptosis-inducing factor, mitochondrion-associated, C-term Pyr_redox_3 PF13738.6 PRP79535.1 - 8.2e-12 45.0 0.1 2e-10 40.5 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP79535.1 - 2.4e-07 30.8 0.0 0.58 10.1 0.0 4.6 4 1 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 PRP79535.1 - 9.6e-07 29.3 2.5 3.9e-05 24.1 0.0 3.6 3 1 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PRP79535.1 - 0.00056 19.2 0.0 2.9 7.0 0.0 3.4 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 PRP79535.1 - 0.001 17.9 0.0 1.9 7.1 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.12 PRP79535.1 - 0.0034 16.5 0.0 0.21 10.6 0.0 2.8 2 1 1 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 PRP79535.1 - 0.056 13.0 0.0 3.5 7.1 0.0 2.9 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 PRP79535.1 - 0.17 10.9 0.2 34 3.4 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A Pkinase_Tyr PF07714.17 PRP79536.1 - 2.1e-40 138.7 0.0 3.9e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79536.1 - 3e-28 98.9 0.0 5.9e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 PRP79536.1 - 1e-09 38.8 1.0 1.2e-08 35.4 0.1 3.0 3 0 0 3 3 3 1 PH domain RE_NgoPII PF09521.10 PRP79536.1 - 0.059 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 NgoPII restriction endonuclease PH_8 PF15409.6 PRP79536.1 - 0.099 12.9 0.1 0.31 11.3 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 PRP79536.1 - 4.3 7.8 5.3 4.4 7.8 1.5 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain HEPN_Swt1 PF18731.1 PRP79536.1 - 5.6 7.3 5.9 1.7 9.0 1.4 2.4 2 0 0 2 2 2 0 Swt1-like HEPN WBP-1 PF11669.8 PRP79537.1 - 0.0018 18.8 0.5 0.0022 18.6 0.5 1.2 1 0 0 1 1 1 1 WW domain-binding protein 1 Shisa PF13908.6 PRP79537.1 - 0.061 13.6 0.9 0.072 13.3 0.9 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator tRNA_anti-like PF12869.7 PRP79537.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like DUF4051 PF13260.6 PRP79537.1 - 1.1 9.0 3.7 1.6 8.5 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) LST1 PF05083.13 PRP79537.1 - 2.4 8.5 4.2 23 5.3 4.2 2.0 1 1 0 1 1 1 0 LST-1 protein SH3_2 PF07653.17 PRP79538.1 - 0.00091 18.9 0.1 0.0023 17.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PRP79538.1 - 0.043 13.7 0.1 0.17 11.8 0.1 2.1 1 1 0 1 1 1 0 Variant SH3 domain Sec1 PF00995.23 PRP79539.1 - 5.6e-123 412.2 1.7 6.4e-123 412.0 1.7 1.0 1 0 0 1 1 1 1 Sec1 family ComZ PF10815.8 PRP79539.1 - 0.077 13.0 0.4 0.29 11.2 0.4 2.0 1 0 0 1 1 1 0 ComZ DUF4891 PF16232.5 PRP79540.1 - 0.018 15.5 0.0 0.79 10.3 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4891) Ank_4 PF13637.6 PRP79540.1 - 0.15 12.6 0.5 1.1e+02 3.5 0.0 4.3 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Y_phosphatase PF00102.27 PRP79542.1 - 2.8e-42 144.9 1.0 5.4e-30 104.7 0.3 3.5 3 0 0 3 3 3 3 Protein-tyrosine phosphatase SH3_2 PF07653.17 PRP79542.1 - 0.002 17.8 0.1 0.0045 16.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PRP79542.1 - 0.095 12.6 0.1 0.32 10.9 0.1 2.0 1 1 0 1 1 1 0 Variant SH3 domain BRCT_2 PF16589.5 PRP79543.1 - 3e-10 40.4 0.2 8.4e-10 38.9 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PRP79543.1 - 2.2e-05 24.8 0.0 4.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PRP79543.1 - 0.003 17.5 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain FAM176 PF14851.6 PRP79544.1 - 4.7 6.9 8.8 0.23 11.1 0.5 2.2 1 1 1 2 2 2 0 FAM176 family Menin PF05053.13 PRP79544.1 - 9.5 4.4 10.0 13 4.0 10.0 1.1 1 0 0 1 1 1 0 Menin DHC_N1 PF08385.12 PRP79545.1 - 2.9e-13 49.3 0.2 5.3e-13 48.5 0.0 1.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 ACP PF06857.11 PRP79545.1 - 0.0086 16.3 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Malonate decarboxylase delta subunit (MdcD) Peptidase_S41_N PF11918.8 PRP79545.1 - 0.065 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP WD40 PF00400.32 PRP79546.1 - 2.2e-11 44.1 9.8 0.00014 22.6 0.2 7.3 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP79546.1 - 0.00062 20.0 0.4 0.15 12.3 0.1 4.5 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Asp_protease PF09668.10 PRP79546.1 - 0.089 12.6 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease PQQ_3 PF13570.6 PRP79546.1 - 0.63 10.6 0.0 0.63 10.6 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain V_ATPase_I PF01496.19 PRP79547.1 - 1.6e-302 1005.4 0.4 2e-302 1005.2 0.4 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4355 PF14265.6 PRP79547.1 - 0.052 13.8 3.1 1.5 9.1 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF948 PF06103.11 PRP79547.1 - 0.061 13.6 0.5 2.4 8.5 0.3 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4298 PF14131.6 PRP79547.1 - 0.1 12.5 3.3 0.086 12.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) NumbF PF06311.12 PRP79547.1 - 0.13 12.9 0.1 0.34 11.5 0.1 1.7 1 0 0 1 1 1 0 NUMB domain Streptin-Immun PF11083.8 PRP79547.1 - 0.14 12.5 2.7 0.6 10.5 0.1 2.5 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein DUF1664 PF07889.12 PRP79547.1 - 1.1 9.3 4.3 6.6 6.8 1.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 PRP79547.1 - 6.7 7.2 9.3 15 6.1 0.6 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) EGF_2 PF07974.13 PRP79548.1 - 4.8e-06 26.8 53.9 0.017 15.5 11.0 4.0 3 0 0 3 3 3 3 EGF-like domain Laminin_EGF PF00053.24 PRP79548.1 - 0.0014 18.7 40.3 0.15 12.2 4.2 3.7 2 1 1 3 3 3 3 Laminin EGF domain TIG PF01833.24 PRP79548.1 - 0.014 15.5 1.0 0.014 15.5 1.0 2.4 2 0 0 2 2 2 0 IPT/TIG domain Alliinase_C PF04864.13 PRP79548.1 - 0.2 10.5 0.2 0.33 9.8 0.2 1.2 1 0 0 1 1 1 0 Allinase CorA PF01544.18 PRP79549.1 - 4.3e-55 187.1 4.3 6.6e-55 186.5 4.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF5082 PF16888.5 PRP79549.1 - 0.019 15.2 0.9 0.031 14.5 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) FliD_C PF07195.12 PRP79549.1 - 0.021 14.2 0.2 0.028 13.8 0.2 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus CoaE PF01121.20 PRP79549.1 - 0.036 13.8 0.4 0.12 12.0 0.2 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase SE PF08491.10 PRP79549.1 - 0.039 13.0 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 Squalene epoxidase Sec63 PF02889.16 PRP79549.1 - 0.04 13.1 0.1 0.073 12.2 0.1 1.4 1 0 0 1 1 1 0 Sec63 Brl domain DUF3671 PF12420.8 PRP79549.1 - 0.11 12.6 1.8 0.3 11.2 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function Shugoshin_C PF07557.11 PRP79550.1 - 7.4e-06 25.7 1.6 2.4e-05 24.0 1.6 2.0 1 0 0 1 1 1 1 Shugoshin C terminus CCCAP PF15964.5 PRP79550.1 - 0.0047 15.3 7.7 0.0085 14.4 7.7 1.3 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family Nebulin PF00880.18 PRP79550.1 - 0.0051 16.7 0.4 0.017 15.0 0.4 2.0 1 0 0 1 1 1 1 Nebulin repeat DUF2400 PF09674.10 PRP79550.1 - 0.057 13.4 1.1 0.093 12.7 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) TPR_MLP1_2 PF07926.12 PRP79550.1 - 0.39 10.8 11.4 1.9 8.6 1.6 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Itfg2 PF15907.5 PRP79550.1 - 0.47 9.4 2.3 5.7 5.9 0.0 2.5 2 1 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF3450 PF11932.8 PRP79550.1 - 1.9 7.7 10.6 0.3 10.3 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 PRP79550.1 - 3.2 5.5 9.3 6.4 4.5 9.3 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family PspA_IM30 PF04012.12 PRP79550.1 - 4.4 6.8 12.8 5.4 6.5 9.4 2.5 2 1 0 2 2 2 0 PspA/IM30 family TMPIT PF07851.13 PRP79550.1 - 4.7 6.4 7.4 7.5 5.7 7.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein YabA PF06156.13 PRP79550.1 - 5.7 7.6 11.4 0.12 13.1 1.2 2.9 2 1 1 3 3 2 0 Initiation control protein YabA UCR_UQCRX_QCR9 PF05365.12 PRP79551.1 - 4e-15 55.5 0.0 4.4e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ribosomal_S8e PF01201.22 PRP79552.1 - 1.3e-49 167.9 0.5 2.2e-49 167.2 0.5 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e ArfGap PF01412.18 PRP79554.1 - 1.1e-32 112.6 2.2 1.1e-32 112.6 2.2 2.2 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf Sad1_UNC PF07738.13 PRP79555.1 - 3.2e-29 101.6 0.1 6.9e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 PRP79555.1 - 0.0027 17.8 0.0 0.0027 17.8 0.0 2.4 4 0 0 4 4 4 1 F5/8 type C domain Rep_Org_C PF06926.11 PRP79555.1 - 0.026 14.8 0.3 0.2 12.0 0.1 2.4 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus FAP206 PF12018.8 PRP79555.1 - 0.15 11.5 3.6 0.32 10.4 3.6 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF417 PF04224.12 PRP79555.1 - 0.15 11.6 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF417 DUF4248 PF14053.6 PRP79556.1 - 0.00062 19.7 0.0 0.96 9.5 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4248) LRR_4 PF12799.7 PRP79556.1 - 0.004 17.5 5.4 0.91 10.0 0.4 4.5 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF4347 PF14252.6 PRP79556.1 - 0.14 12.0 0.1 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4347) Glyco_hydro_71 PF03659.14 PRP79557.1 - 8.4e-81 271.7 22.1 1.4e-80 271.0 22.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Pro_isomerase PF00160.21 PRP79557.1 - 8.3e-38 130.1 0.0 2.3e-37 128.7 0.0 1.8 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EGF_2 PF07974.13 PRP79557.1 - 2.6e-06 27.7 66.1 0.0002 21.7 13.2 4.5 4 0 0 4 4 4 3 EGF-like domain TIG PF01833.24 PRP79557.1 - 0.00065 19.7 0.5 0.004 17.2 0.5 2.5 1 0 0 1 1 1 1 IPT/TIG domain DUF4604 PF15377.6 PRP79557.1 - 0.011 16.2 0.2 0.011 16.2 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4604) Pur_ac_phosph_N PF16656.5 PRP79557.1 - 0.086 13.4 0.5 0.93 10.1 0.0 2.8 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain CRAL_TRIO PF00650.20 PRP79558.1 - 2.8e-27 95.4 0.0 4.6e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PRP79558.1 - 4.2e-11 43.2 0.0 7.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP79558.1 - 0.067 13.4 0.8 0.21 11.8 0.8 1.9 1 1 0 1 1 1 0 CRAL/TRIO, N-terminal domain CLASP_N PF12348.8 PRP79559.1 - 0.0052 16.4 0.2 0.0085 15.7 0.2 1.3 1 0 0 1 1 1 1 CLASP N terminal RasGEF_N_2 PF14663.6 PRP79559.1 - 0.051 14.0 0.2 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Prok-RING_4 PF14447.6 PRP79559.1 - 0.11 12.4 4.8 1.6 8.7 0.4 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 CTU2 PF10288.9 PRP79559.1 - 0.79 10.0 5.6 18 5.6 2.7 3.6 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Pkinase_Tyr PF07714.17 PRP79560.1 - 1.5e-47 162.1 0.0 2.4e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79560.1 - 4e-35 121.5 0.0 7.4e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP79560.1 - 2e-06 28.2 3.2 5.6e-06 26.8 3.2 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Cad PF03596.13 PRP79560.1 - 0.12 12.2 0.4 0.24 11.2 0.4 1.4 1 0 0 1 1 1 0 Cadmium resistance transporter UPF0203 PF05254.12 PRP79561.1 - 6.5e-17 61.5 1.4 7.7e-17 61.3 1.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 PRP79561.1 - 0.00084 19.6 1.3 0.0015 18.8 1.3 1.4 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 PRP79561.1 - 0.0028 17.6 0.6 0.053 13.5 0.0 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 PRP79561.1 - 0.0031 17.5 2.1 0.87 9.7 0.2 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 PRP79561.1 - 0.034 14.3 2.4 0.051 13.7 0.1 2.1 2 0 0 2 2 2 0 CHCH domain zf_Hakai PF18408.1 PRP79562.1 - 0.016 14.9 0.3 0.072 12.8 0.1 2.1 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain His_Phos_2 PF00328.22 PRP79563.1 - 1.8e-14 53.9 0.1 2.6e-11 43.5 0.1 2.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Dioxygenase_C PF00775.21 PRP79565.1 - 1.8e-07 30.8 0.0 3.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Uricase PF01014.18 PRP79567.1 - 0.077 13.3 0.0 0.077 13.3 0.0 1.1 1 0 0 1 1 1 0 Uricase Solute_trans_a PF03619.16 PRP79568.1 - 7.8e-77 258.4 19.3 9.1e-77 258.1 19.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BK_channel_a PF03493.18 PRP79571.1 - 1.4e-15 57.3 0.0 1.9e-14 53.6 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PRP79571.1 - 3.7e-12 46.0 3.6 3.7e-12 46.0 3.6 2.4 2 0 0 2 2 2 1 Ion channel GPS PF01825.21 PRP79571.1 - 6.6e-09 36.2 7.0 1.5e-08 35.0 7.0 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Ion_trans PF00520.31 PRP79571.1 - 4.3e-08 32.7 13.2 4.3e-08 32.7 13.2 1.9 2 0 0 2 2 2 1 Ion transport protein Pkinase_Tyr PF07714.17 PRP79571.1 - 5.3e-06 25.9 0.1 2.9e-05 23.5 0.0 2.1 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79571.1 - 7e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TrkA_C PF02080.21 PRP79571.1 - 0.077 12.8 0.8 0.37 10.7 0.0 2.6 3 0 0 3 3 3 0 TrkA-C domain CH PF00307.31 PRP79572.1 - 9.1e-34 115.9 0.1 1.3e-15 57.5 0.1 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain C2 PF00168.30 PRP79572.1 - 1.4e-16 60.6 0.0 3.2e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain CAMSAP_CH PF11971.8 PRP79572.1 - 5.8e-08 32.5 0.3 0.00027 20.7 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain TipAS PF07739.13 PRP79572.1 - 3.9 8.1 9.5 55 4.3 0.0 2.9 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain MAT1 PF06391.13 PRP79572.1 - 6 6.6 28.1 19 5.0 27.5 2.1 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF1700 PF08006.11 PRP79572.1 - 8.8 5.8 6.2 16 5.0 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) EF-hand_12 PF17901.1 PRP79573.1 - 3.9e-26 91.3 2.9 5e-26 91.0 0.5 2.5 3 0 0 3 3 3 1 EF-hand fold domain STATa_Ig PF18214.1 PRP79573.1 - 8.7e-21 74.2 0.9 2e-20 73.0 0.9 1.7 1 0 0 1 1 1 1 STATa Immunoglobulin-like domain SH2 PF00017.24 PRP79573.1 - 3.5e-08 33.4 0.0 1.2e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Dict-STAT-coil PF09267.10 PRP79573.1 - 7.9e-07 29.5 10.0 2.1e-06 28.1 10.0 1.7 1 0 0 1 1 1 1 Dictyostelium STAT, coiled coil Cbl_N3 PF02762.14 PRP79573.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain DUF1160 PF06648.11 PRP79573.1 - 0.0096 15.9 2.9 0.74 9.8 0.1 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF1160) DUF4642 PF15484.6 PRP79573.1 - 0.21 11.8 0.1 0.21 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) eIF-4B PF06273.11 PRP79573.1 - 0.34 9.9 2.8 0.55 9.2 2.8 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Dioxygenase_C PF00775.21 PRP79575.1 - 9.7e-08 31.7 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Paf67 PF10255.9 PRP79576.1 - 6.3e-150 499.7 4.5 9.9e-150 499.0 4.5 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 Homeodomain PF00046.29 PRP79577.1 - 3.2e-16 58.9 2.6 8.4e-16 57.6 2.6 1.7 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 PRP79577.1 - 0.014 15.2 0.3 0.028 14.2 0.3 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Homeobox_KN PF05920.11 PRP79577.1 - 0.077 12.9 4.6 0.51 10.3 3.0 2.9 2 1 0 2 2 2 0 Homeobox KN domain AMPK1_CBM PF16561.5 PRP79579.1 - 2.5e-08 34.0 0.2 5.9e-08 32.8 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Hexapep PF00132.24 PRP79579.1 - 0.39 10.5 2.2 3.7 7.4 0.2 3.1 2 1 1 3 3 3 0 Bacterial transferase hexapeptide (six repeats) DUF3331 PF11811.8 PRP79580.1 - 0.13 12.2 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) ADK PF00406.22 PRP79581.1 - 1.1e-36 126.1 0.0 2.2e-13 50.6 0.0 4.7 4 0 0 4 4 4 4 Adenylate kinase AAA_17 PF13207.6 PRP79581.1 - 3.9e-23 82.4 0.1 2.8e-05 24.6 0.0 5.1 5 0 0 5 5 4 4 AAA domain FAP206 PF12018.8 PRP79581.1 - 4.9e-20 72.2 0.1 0.0031 17.1 0.0 6.0 4 1 0 5 5 5 4 Domain of unknown function AAA_18 PF13238.6 PRP79581.1 - 2.6e-15 57.1 0.2 0.02 15.4 0.0 5.1 4 0 0 4 4 4 4 AAA domain AAA_33 PF13671.6 PRP79581.1 - 9.9e-11 42.0 0.0 0.015 15.5 0.0 4.6 4 0 0 4 4 4 2 AAA domain SKI PF01202.22 PRP79581.1 - 4.2e-07 30.2 0.0 0.073 13.2 0.0 3.8 3 0 0 3 3 3 2 Shikimate kinase Cytidylate_kin PF02224.18 PRP79581.1 - 5.2e-07 29.6 0.0 0.19 11.4 0.0 3.9 4 0 0 4 4 4 2 Cytidylate kinase YHS PF04945.13 PRP79581.1 - 7.9e-07 29.1 0.1 0.055 13.6 0.0 4.4 4 0 0 4 4 4 2 YHS domain AAA_28 PF13521.6 PRP79581.1 - 9.2e-07 29.2 1.0 0.63 10.3 0.0 5.2 4 1 1 5 5 5 1 AAA domain Hydin_ADK PF17213.3 PRP79581.1 - 1.1e-05 25.8 0.6 0.038 14.3 0.0 3.2 4 0 0 4 4 2 2 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 PRP79581.1 - 1.8e-05 25.0 0.0 2.6 8.3 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 PRP79581.1 - 0.00049 20.5 0.3 9.4 6.7 0.0 4.6 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 PRP79581.1 - 0.0018 18.4 0.3 0.093 12.9 0.3 3.2 2 1 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.27 PRP79581.1 - 0.003 18.1 0.0 9.7 6.7 0.0 4.4 4 0 0 4 4 4 0 ABC transporter KTI12 PF08433.10 PRP79581.1 - 0.0064 16.0 0.1 3 7.2 0.0 3.4 3 0 0 3 3 3 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 PRP79581.1 - 0.016 15.2 0.3 1.8 8.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 PRP79581.1 - 0.022 14.7 0.0 10 6.0 0.0 3.3 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_24 PF13479.6 PRP79581.1 - 0.03 14.0 0.0 5.5 6.7 0.0 3.5 4 0 0 4 4 4 0 AAA domain Dpy-30 PF05186.13 PRP79581.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Dpy-30 motif AAA_16 PF13191.6 PRP79581.1 - 0.072 13.5 0.1 1.1 9.6 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain Zeta_toxin PF06414.12 PRP79581.1 - 0.11 11.8 0.0 0.93 8.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 PRP79581.1 - 0.11 12.9 0.0 99 3.4 0.0 3.9 4 0 0 4 4 3 0 RNA helicase AAA_29 PF13555.6 PRP79581.1 - 0.13 12.0 0.0 11 5.9 0.0 3.8 5 0 0 5 5 5 0 P-loop containing region of AAA domain Jas PF16135.5 PRP79582.1 - 5.1e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 TPL-binding domain in jasmonate signalling F-box-like PF12937.7 PRP79582.1 - 0.00015 21.5 0.2 0.00029 20.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP79582.1 - 0.00024 20.9 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain Peptidase_C1 PF00112.23 PRP79583.1 - 3.4e-43 148.2 8.5 6e-43 147.5 8.5 1.4 1 0 0 1 1 1 1 Papain family cysteine protease PAN_4 PF14295.6 PRP79583.1 - 1.2e-07 31.5 5.3 1.2e-07 31.5 5.3 2.6 4 0 0 4 4 4 1 PAN domain Peptidase_C1_2 PF03051.15 PRP79583.1 - 2.4e-05 23.3 1.5 0.00076 18.4 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PAN_1 PF00024.26 PRP79583.1 - 4.2e-05 23.4 1.6 4.2e-05 23.4 1.6 2.2 3 0 0 3 3 3 1 PAN domain Inhibitor_I29 PF08246.12 PRP79583.1 - 0.00016 22.0 1.5 0.00042 20.7 1.5 1.6 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PAN_2 PF08276.11 PRP79583.1 - 0.00029 20.9 2.0 0.00029 20.9 2.0 2.5 2 0 0 2 2 2 1 PAN-like domain Zip PF02535.22 PRP79584.1 - 2e-46 158.8 9.8 4e-46 157.8 9.8 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter AhpC-TSA PF00578.21 PRP79584.1 - 3.8e-30 104.3 0.0 6.4e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 PRP79584.1 - 3e-11 43.0 0.0 6.6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 PRP79584.1 - 3.3e-10 39.9 0.0 1.1e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Redoxin Auxin_canalis PF05703.11 PRP79584.1 - 1.8 8.4 3.9 0.4 10.6 0.5 1.6 2 0 0 2 2 2 0 Auxin canalisation F-box PF00646.33 PRP79585.1 - 0.00037 20.3 0.1 0.00083 19.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 PRP79585.1 - 0.0016 19.0 0.3 13 6.5 0.0 5.5 5 1 1 6 6 6 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP79585.1 - 0.017 15.0 0.5 0.051 13.5 0.1 2.0 2 0 0 2 2 2 0 F-box-like AKAP95 PF04988.12 PRP79585.1 - 0.068 13.4 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) TFIID_20kDa PF03847.13 PRP79586.1 - 7.6e-19 68.0 1.1 9.3e-19 67.7 0.2 1.5 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 PRP79586.1 - 4.2e-05 23.9 0.2 9.6e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PRP79586.1 - 0.00043 20.5 0.1 0.00083 19.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone HSP70 PF00012.20 PRP79588.1 - 9.1e-109 364.3 0.5 1e-108 364.1 0.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP79588.1 - 1.5e-09 37.1 0.1 7.9e-08 31.5 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 PRP79588.1 - 0.031 13.5 0.5 0.069 12.4 0.1 1.7 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.10 PRP79588.1 - 0.034 13.2 0.1 0.046 12.7 0.1 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain DUF1894 PF08979.11 PRP79588.1 - 0.17 12.3 0.0 0.81 10.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) PsbH PF00737.20 PRP79589.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Vps36-NZF-N PF16988.5 PRP79589.1 - 0.24 10.8 0.1 0.24 10.8 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Folliculin_C PF16692.5 PRP79590.1 - 8.6e-33 114.0 0.0 5.1e-32 111.4 0.0 2.1 2 0 0 2 2 2 1 Folliculin C-terminal domain Folliculin PF11704.8 PRP79590.1 - 1.2e-32 113.3 0.0 2.6e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Itfg2 PF15907.5 PRP79591.1 - 5.4e-29 101.3 0.0 1.4e-15 57.2 0.0 2.9 2 1 1 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 DUF547 PF04784.14 PRP79591.1 - 2.5e-21 76.0 0.0 5.1e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF547 BBS2_Mid PF14783.6 PRP79591.1 - 4.1e-08 33.2 1.3 0.0061 16.6 0.1 4.1 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.6 PRP79591.1 - 3.8e-05 24.2 0.7 0.058 14.0 0.0 3.0 2 1 0 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PHTB1_N PF14727.6 PRP79591.1 - 0.00087 18.8 0.0 0.18 11.1 0.0 3.2 3 0 0 3 3 3 1 PTHB1 N-terminus DUF919 PF06034.11 PRP79591.1 - 0.027 14.3 1.6 0.044 13.6 0.3 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) BBS2_C PF14782.6 PRP79591.1 - 0.074 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal WD40_like PF17005.5 PRP79591.1 - 0.11 11.8 1.6 1.2 8.4 0.1 2.8 3 0 0 3 3 3 0 WD40-like domain FG-GAP PF01839.23 PRP79591.1 - 1.4 9.1 4.1 1.8 8.8 0.3 2.4 2 0 0 2 2 2 0 FG-GAP repeat Cactin_mid PF10312.9 PRP79592.1 - 8.9e-34 117.0 11.7 8.9e-34 117.0 11.7 1.9 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.9 PRP79592.1 - 3.6e-32 110.9 3.9 9.8e-32 109.5 3.9 1.7 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein RasGAP PF00616.19 PRP79593.1 - 1.4e-10 41.2 4.2 7.9e-09 35.5 0.0 3.6 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase NUC153 PF08159.12 PRP79593.1 - 1.7e-05 24.5 0.5 3.6e-05 23.5 0.5 1.6 1 0 0 1 1 1 1 NUC153 domain Str_synth PF03088.16 PRP79593.1 - 0.016 15.3 0.0 0.082 13.0 0.0 2.2 2 0 0 2 2 2 0 Strictosidine synthase Cytochrom_D1 PF02239.16 PRP79593.1 - 0.067 11.7 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF410 PF04190.13 PRP79594.1 - 3e-67 227.1 0.0 4.6e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF4363 PF14276.6 PRP79594.1 - 0.23 11.6 2.7 17 5.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4363) UPF0556 PF10572.9 PRP79595.1 - 8.5e-14 51.3 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 OSCP PF00213.18 PRP79596.1 - 1.5e-18 67.5 0.1 2.7e-18 66.7 0.1 1.4 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit ASL_C2 PF14698.6 PRP79596.1 - 0.079 13.7 0.0 0.25 12.1 0.0 1.8 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal DUF4279 PF14106.6 PRP79596.1 - 0.13 12.5 0.0 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) zf-C3HC4_2 PF13923.6 PRP79597.1 - 6.6e-06 25.9 11.8 1.2e-05 25.0 10.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP79597.1 - 6.6e-06 26.0 3.9 6.6e-06 26.0 3.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 PRP79597.1 - 3.1e-05 24.0 10.1 6.6e-05 23.0 10.1 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 PRP79597.1 - 6.4e-05 22.7 10.3 0.00013 21.7 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP79597.1 - 0.0006 19.9 12.3 0.0014 18.7 12.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PRP79597.1 - 0.0007 19.9 9.4 0.0018 18.6 9.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP79597.1 - 0.0011 18.7 11.9 0.002 17.9 11.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP79597.1 - 0.0043 16.9 14.0 0.048 13.5 14.4 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 PRP79597.1 - 0.012 15.5 6.5 0.033 14.1 6.5 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) U-box PF04564.15 PRP79597.1 - 0.042 14.0 0.6 0.26 11.5 0.1 2.4 2 0 0 2 2 2 0 U-box domain BRICHOS PF04089.14 PRP79597.1 - 0.062 13.6 0.3 0.23 11.7 0.1 2.0 1 1 1 2 2 2 0 BRICHOS domain zf-RING_5 PF14634.6 PRP79597.1 - 0.072 13.1 14.9 0.063 13.3 12.6 2.1 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_6 PF14835.6 PRP79597.1 - 0.13 12.2 5.5 0.28 11.1 5.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PRP79597.1 - 0.47 10.3 8.9 0.57 10.0 4.0 2.8 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-WRNIP1_ubi PF18279.1 PRP79597.1 - 3.7 8.4 6.3 5.1 8.0 0.5 2.7 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain ORC2 PF04084.14 PRP79598.1 - 1.6e-72 244.2 2.1 2.2e-72 243.8 2.1 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 IF4E PF01652.18 PRP79599.1 - 4.4e-39 133.8 0.2 5.7e-39 133.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E RIO1 PF01163.22 PRP79601.1 - 1.4e-70 236.7 0.3 2.8e-70 235.7 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 PRP79601.1 - 0.011 14.5 0.4 0.036 12.9 0.1 1.6 1 1 0 1 1 1 0 Fungal protein kinase CPT_N PF16484.5 PRP79601.1 - 0.06 13.3 0.0 0.18 11.8 0.0 1.9 1 0 0 1 1 1 0 Carnitine O-palmitoyltransferase N-terminus Sld5 PF05916.11 PRP79602.1 - 2.8e-05 24.5 0.1 4.8e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 GINS complex protein DUF3375 PF11855.8 PRP79602.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) MoaC PF01967.21 PRP79603.1 - 6.3e-48 162.3 2.9 7.3e-48 162.1 2.9 1.0 1 0 0 1 1 1 1 MoaC family MRPL52 PF18699.1 PRP79603.1 - 0.034 14.3 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Mitoribosomal protein mL52 MULE PF10551.9 PRP79604.1 - 0.0054 17.1 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain WRKY PF03106.15 PRP79604.1 - 0.068 13.4 0.7 0.068 13.4 0.7 2.7 3 0 0 3 3 3 0 WRKY DNA -binding domain DUF2838 PF10998.8 PRP79608.1 - 7.2e-37 126.0 13.2 7.2e-37 126.0 13.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF4199 PF13858.6 PRP79608.1 - 0.71 10.2 0.1 0.71 10.2 0.1 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4199) Rer1 PF03248.13 PRP79609.1 - 1.6e-66 223.3 3.5 1.9e-66 223.0 3.5 1.0 1 0 0 1 1 1 1 Rer1 family Copine PF07002.16 PRP79610.1 - 7.1e-55 185.8 0.0 1.7e-54 184.6 0.0 1.6 1 1 0 1 1 1 1 Copine C2 PF00168.30 PRP79610.1 - 2.4e-20 72.7 0.0 1.4e-10 41.3 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 PRP79610.1 - 3.2e-06 27.4 0.0 4.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 PRP79610.1 - 0.0081 16.4 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Acetyltransf_3 PF13302.7 PRP79611.1 - 1.8e-18 67.5 3.7 6.1e-18 65.8 3.7 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PRP79611.1 - 1.4e-09 37.8 0.5 2.4e-09 37.0 0.5 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP79611.1 - 9.1e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 PRP79611.1 - 0.0005 20.3 0.7 0.00086 19.5 0.7 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Tropomodulin PF03250.14 PRP79611.1 - 0.029 14.4 1.7 0.39 10.8 0.1 2.3 1 1 1 2 2 2 0 Tropomodulin Nmad3 PF18754.1 PRP79611.1 - 0.049 13.2 0.1 0.057 13.0 0.1 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 UPF0086 PF01868.16 PRP79612.1 - 4.4e-27 93.8 0.1 1.1e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Podoplanin PF05808.11 PRP79614.1 - 0.0033 17.5 0.7 0.011 15.8 0.7 1.9 1 0 0 1 1 1 1 Podoplanin VSP PF03302.13 PRP79614.1 - 0.0049 15.8 0.3 0.0049 15.8 0.3 1.8 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF4690 PF15756.5 PRP79614.1 - 0.011 16.4 1.5 0.017 15.7 0.1 2.0 2 0 0 2 2 1 0 Small Novel Rich in Cartilage PepSY_TM PF03929.16 PRP79614.1 - 0.15 11.7 0.2 0.33 10.6 0.2 1.5 1 0 0 1 1 1 0 PepSY-associated TM region Syndecan PF01034.20 PRP79614.1 - 0.19 11.6 1.2 0.48 10.4 1.2 1.6 1 0 0 1 1 1 0 Syndecan domain Thg1C PF14413.6 PRP79614.1 - 0.35 11.0 3.7 0.7 10.1 3.7 1.5 1 0 0 1 1 1 0 Thg1 C terminal domain Insulin_TMD PF17870.1 PRP79614.1 - 0.5 10.5 4.7 0.17 12.0 1.2 2.0 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF809 PF05663.11 PRP79614.1 - 1.2 9.3 4.7 7 6.8 5.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF809) DUF1840 PF08895.11 PRP79614.1 - 1.6 9.1 4.3 1.5 9.2 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) EphA2_TM PF14575.6 PRP79614.1 - 1.7 9.6 0.0 1.7 9.6 0.0 2.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4407 PF14362.6 PRP79614.1 - 4.6 6.5 5.7 0.59 9.4 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PTPLA PF04387.14 PRP79616.1 - 2.1e-48 164.1 6.2 2.6e-48 163.8 6.2 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Rap_GAP PF02145.15 PRP79617.1 - 5.9e-64 215.1 0.1 1.4e-63 213.8 0.1 1.7 1 0 0 1 1 1 1 Rap/ran-GAP PqiA PF04403.13 PRP79618.1 - 1.4e-14 54.2 28.9 2e-09 37.5 6.1 3.0 3 0 0 3 3 3 2 Paraquat-inducible protein A DUF2207 PF09972.9 PRP79618.1 - 0.52 9.0 0.0 0.52 9.0 0.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) ADH_zinc_N PF00107.26 PRP79619.1 - 1.8e-17 63.5 0.3 3.7e-17 62.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 PRP79619.1 - 0.00047 19.7 0.5 0.00069 19.1 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.12 PRP79619.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KR PF08659.10 PRP79619.1 - 0.0078 16.1 0.2 0.013 15.5 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP79619.1 - 0.03 14.2 1.3 0.064 13.1 1.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 PRP79619.1 - 0.14 11.7 0.4 0.22 11.0 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 PRP79619.1 - 0.18 12.0 0.9 0.38 10.9 0.9 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Herpes_UL92 PF03048.14 PRP79620.1 - 0.1 12.4 0.1 5.3 6.8 0.2 3.0 3 0 0 3 3 3 0 UL92 family DUF4061 PF13270.6 PRP79621.1 - 2.8e-10 40.4 1.9 3.8e-10 39.9 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) DUF5401 PF17380.2 PRP79621.1 - 0.019 13.1 0.7 0.018 13.1 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) ERp29 PF07749.12 PRP79621.1 - 0.082 13.8 0.2 0.66 10.9 0.0 2.2 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain RNase_H2-Ydr279 PF09468.10 PRP79621.1 - 0.082 13.1 0.4 7 6.8 0.1 2.1 1 1 1 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain SLT_L PF14718.6 PRP79621.1 - 0.21 11.7 0.6 6.5 7.0 0.1 2.4 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain CCDC84 PF14968.6 PRP79622.1 - 3.6e-34 118.9 8.4 5.9e-33 114.9 8.4 2.3 1 1 0 1 1 1 1 Coiled coil protein 84 Methyltransf_16 PF10294.9 PRP79622.1 - 1.5e-29 103.0 0.1 3.4e-29 101.8 0.1 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 PRP79622.1 - 0.0071 16.2 0.1 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF1289 PF06945.13 PRP79622.1 - 0.12 12.2 0.7 0.3 10.9 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) Lyase_8 PF02278.18 PRP79623.1 - 3.1e-55 187.4 1.5 3.1e-55 187.4 1.5 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 PRP79623.1 - 3.1e-20 72.4 0.1 5.2e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 PRP79623.1 - 7.9e-11 42.3 1.2 3.1e-10 40.4 0.0 2.7 3 0 0 3 3 3 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain AAA PF00004.29 PRP79624.1 - 3e-17 63.3 0.0 1.9e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PRP79624.1 - 4.9e-09 36.4 0.0 1.1e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 PRP79624.1 - 2.2e-06 27.7 0.0 6.7e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 PRP79624.1 - 1e-05 25.6 0.0 3.2e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP79624.1 - 1.4e-05 25.6 0.1 0.00015 22.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP79624.1 - 7.9e-05 22.9 0.4 0.083 13.2 0.1 3.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 PRP79624.1 - 0.00016 21.5 0.2 0.00039 20.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PRP79624.1 - 0.00046 20.4 0.0 0.0026 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP79624.1 - 0.00047 20.5 0.0 0.0044 17.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 PRP79624.1 - 0.001 18.4 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 PRP79624.1 - 0.0018 18.7 0.1 0.0063 16.9 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain TsaE PF02367.17 PRP79624.1 - 0.0031 17.5 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 PRP79624.1 - 0.0038 17.0 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PRP79624.1 - 0.0061 17.0 1.0 0.047 14.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF3512 PF12024.8 PRP79624.1 - 0.012 15.1 1.2 0.029 13.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) NTPase_1 PF03266.15 PRP79624.1 - 0.014 15.3 0.2 0.06 13.3 0.1 2.1 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 PRP79624.1 - 0.015 15.8 0.2 0.088 13.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter RhoGEF67_u2 PF16614.5 PRP79624.1 - 0.02 14.9 0.3 0.12 12.5 0.0 2.5 3 0 0 3 3 1 0 Unstructured region two on RhoGEF 6 and 7 AAA_25 PF13481.6 PRP79624.1 - 0.021 14.4 0.9 0.27 10.8 0.3 2.7 2 1 0 3 3 3 0 AAA domain NACHT PF05729.12 PRP79624.1 - 0.033 14.1 0.1 0.87 9.5 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 PRP79624.1 - 0.035 14.3 0.5 0.081 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain Polyoma_lg_T_C PF06431.11 PRP79624.1 - 0.038 12.9 0.0 0.084 11.7 0.0 1.5 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus TIP49 PF06068.13 PRP79624.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 PRP79624.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 PRP79624.1 - 0.074 12.8 0.2 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 PRP79624.1 - 0.075 12.2 0.0 0.32 10.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 PRP79624.1 - 0.086 12.2 0.3 3.9 6.8 0.1 3.3 3 1 1 4 4 4 0 KaiC DOG1 PF14144.6 PRP79624.1 - 0.097 12.9 0.0 5 7.4 0.0 3.4 4 0 0 4 4 4 0 Seed dormancy control SKI PF01202.22 PRP79624.1 - 0.12 12.5 0.2 0.44 10.7 0.0 2.1 2 0 0 2 2 1 0 Shikimate kinase T2SSE PF00437.20 PRP79624.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribosomal_60s PF00428.19 PRP79625.1 - 3e-11 43.8 0.0 5.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cnd3 PF12719.7 PRP79625.1 - 0.079 12.1 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Pre-PUA PF17832.1 PRP79626.1 - 1.6e-20 73.6 0.0 2.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 PRP79627.1 - 1.5e-06 28.1 0.1 1.6e-06 28.0 0.1 1.0 1 0 0 1 1 1 1 PUA domain PagL PF09411.10 PRP79627.1 - 0.09 12.9 0.0 0.092 12.9 0.0 1.1 1 0 0 1 1 1 0 Lipid A 3-O-deacylase (PagL) EF-hand_7 PF13499.6 PRP79628.1 - 3.5e-09 37.0 0.0 0.0041 17.6 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP79628.1 - 2.6e-05 23.8 0.0 0.15 12.0 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PRP79628.1 - 0.0032 16.9 0.0 0.4 10.3 0.0 2.9 4 0 0 4 4 4 1 EF hand IPP-2 PF04979.14 PRP79629.1 - 7.5e-20 72.0 11.1 7.5e-20 72.0 11.1 1.5 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) SNF2_N PF00176.23 PRP79629.1 - 0.027 13.2 0.1 0.027 13.2 0.1 1.4 2 0 0 2 2 2 0 SNF2 family N-terminal domain HTH_45 PF14947.6 PRP79630.1 - 0.05 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix polyprenyl_synt PF00348.17 PRP79632.1 - 1.6e-90 302.6 0.0 2.1e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Drf_FH1 PF06346.12 PRP79633.1 - 0.24 11.1 10.2 0.47 10.2 10.2 1.6 1 1 0 1 1 1 0 Formin Homology Region 1 EGF_2 PF07974.13 PRP79634.1 - 0.02 15.2 3.3 0.04 14.3 3.3 1.4 1 0 0 1 1 1 0 EGF-like domain Brr6_like_C_C PF10104.9 PRP79635.1 - 3.4 7.4 6.2 11 5.8 0.1 2.7 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain SLC3A2_N PF16028.5 PRP79635.1 - 4 7.1 9.6 0.15 11.6 0.6 2.8 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus DUF4538 PF15061.6 PRP79635.1 - 4.8 7.0 7.0 9 6.1 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) DUF2401 PF10287.9 PRP79636.1 - 2.6e-25 89.4 1.5 2.8e-18 66.3 0.9 2.6 1 1 1 2 2 2 2 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 PRP79636.1 - 1.4e-06 28.6 0.0 4.3e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Kinesin PF00225.23 PRP79637.1 - 1.4e-106 356.2 0.1 1.4e-106 356.2 0.1 4.9 4 2 2 6 6 6 1 Kinesin motor domain Microtub_bd PF16796.5 PRP79637.1 - 1.8e-49 167.5 0.0 1.8e-49 167.5 0.0 4.2 3 1 0 3 3 3 1 Microtubule binding RNA_pol_Rpb2_3 PF04565.16 PRP79637.1 - 5.3 7.3 5.3 30 4.9 0.2 3.1 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 3 DLH PF01738.18 PRP79638.1 - 3.4e-21 75.8 0.0 2.7e-17 63.0 0.0 2.0 2 0 0 2 2 2 2 Dienelactone hydrolase family SapB_1 PF05184.15 PRP79638.1 - 0.26 11.3 1.4 0.43 10.6 0.4 1.9 2 0 0 2 2 2 0 Saposin-like type B, region 1 adh_short PF00106.25 PRP79639.1 - 9.5e-29 100.2 0.0 1.3e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP79639.1 - 1.6e-24 86.8 0.0 2.1e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP79639.1 - 0.00097 19.1 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Pkinase PF00069.25 PRP79640.1 - 0.029 13.8 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain La PF05383.17 PRP79641.1 - 1.1e-19 70.2 0.1 3.1e-19 68.8 0.1 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 PRP79641.1 - 1.2e-11 44.2 0.0 4e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPS PF01825.21 PRP79641.1 - 2.2e-11 44.1 2.8 2.2e-11 44.1 2.8 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP79641.1 - 1.7e-10 40.6 0.0 5.4e-08 32.4 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP79641.1 - 2.4e-10 40.3 0.2 2.6e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain SUZ-C PF12901.7 PRP79641.1 - 0.0021 18.0 1.6 0.0057 16.6 1.6 1.7 1 0 0 1 1 1 1 SUZ-C motif Snf7 PF03357.21 PRP79641.1 - 0.15 11.6 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Snf7 YajC PF02699.15 PRP79641.1 - 0.47 10.4 1.5 20 5.2 0.4 3.2 3 0 0 3 3 3 0 Preprotein translocase subunit Suf PF05843.14 PRP79641.1 - 9 6.2 12.9 3.3 7.6 1.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) WSC PF01822.19 PRP79642.1 - 1.6e-50 169.2 74.0 4.5e-15 55.6 10.2 5.2 5 0 0 5 5 5 4 WSC domain PQQ_3 PF13570.6 PRP79642.1 - 6.1e-05 23.4 2.5 0.034 14.6 0.1 4.4 3 0 0 3 3 3 1 PQQ-like domain DUF1573 PF07610.11 PRP79642.1 - 9.1e-05 22.4 2.5 0.082 12.9 0.0 4.0 4 1 0 4 4 4 2 Protein of unknown function (DUF1573) ASH PF15780.5 PRP79642.1 - 0.014 15.6 8.3 7.9 6.8 0.0 3.9 4 0 0 4 4 4 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SPX PF03105.19 PRP79642.1 - 6.5 6.6 10.7 9.6 6.0 10.7 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 PRP79642.1 - 7.5 5.6 21.1 11 5.0 21.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PB1 PF00564.24 PRP79643.1 - 1.5e-08 34.5 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 PB1 domain baeRF_family11 PF18855.1 PRP79643.1 - 0.047 14.0 0.0 2.1 8.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 11 MCM PF00493.23 PRP79646.1 - 1.2e-94 315.7 0.0 1.8e-94 315.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MIP PF00230.20 PRP79646.1 - 2.3e-31 109.3 7.4 3.7e-31 108.6 7.4 1.3 1 0 0 1 1 1 1 Major intrinsic protein MCM_OB PF17207.3 PRP79646.1 - 9.2e-29 99.9 0.5 1.8e-28 98.9 0.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PRP79646.1 - 1.9e-20 73.0 0.7 4.3e-20 71.9 0.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PRP79646.1 - 9.6e-12 45.4 1.2 3.8e-11 43.5 0.5 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 PRP79646.1 - 1.2e-08 35.0 0.1 1.5e-07 31.4 0.0 3.0 5 0 0 5 5 5 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PRP79646.1 - 2.1e-07 30.5 0.2 2.6e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PRP79646.1 - 0.0095 15.8 0.0 0.037 13.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF368 PF04018.13 PRP79646.1 - 0.04 13.5 1.0 0.09 12.3 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF368) PIG-S PF10510.9 PRP79646.1 - 0.15 10.9 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein SVIP PF15811.5 PRP79646.1 - 1.1 9.7 4.1 3 8.3 4.1 1.7 1 0 0 1 1 1 0 Small VCP/p97-interacting protein AAA_16 PF13191.6 PRP79646.1 - 2.7 8.4 4.9 3 8.2 0.1 2.9 2 2 0 2 2 2 0 AAA ATPase domain Carn_acyltransf PF00755.20 PRP79649.1 - 3.5e-192 640.1 0.0 4.9e-192 639.7 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Pkinase_Tyr PF07714.17 PRP79649.1 - 6.4e-80 268.2 0.0 1e-79 267.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79649.1 - 1.9e-49 168.4 0.0 3.6e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 PRP79649.1 - 0.0023 17.8 0.9 0.0052 16.7 0.9 1.5 1 0 0 1 1 1 1 TMEM154 protein family Haspin_kinase PF12330.8 PRP79649.1 - 0.011 14.7 0.1 0.031 13.2 0.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP79649.1 - 0.032 13.0 0.1 0.069 11.9 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 PRP79649.1 - 0.071 12.7 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 PRP79649.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Chlam_PMP PF02415.17 PRP79649.1 - 5 7.8 51.4 0.83 10.3 1.1 9.9 10 0 0 10 10 10 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NAD_binding_10 PF13460.6 PRP79650.1 - 6.9e-09 35.9 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PRP79650.1 - 1.3e-08 34.6 0.0 2.8e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PRP79650.1 - 1.7e-07 31.1 0.0 5.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 PRP79650.1 - 0.00038 20.0 0.0 0.00059 19.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 PRP79650.1 - 0.0012 18.3 0.1 0.087 12.2 0.0 2.4 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PRP79650.1 - 0.018 14.2 0.0 0.5 9.4 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 PRP79650.1 - 0.021 13.8 0.0 0.21 10.6 0.0 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 PRP79650.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 KR domain Glu-tRNAGln PF02686.15 PRP79650.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Homeodomain PF00046.29 PRP79652.1 - 3.3e-19 68.5 2.4 3.3e-19 68.5 2.4 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP79652.1 - 0.00011 22.1 0.5 0.00032 20.5 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain TusA PF01206.17 PRP79652.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Sulfurtransferase TusA DUF521 PF04412.13 PRP79652.1 - 0.15 10.7 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RasGEF PF00617.19 PRP79654.1 - 2.2e-57 194.1 4.4 2.6e-57 193.9 0.6 3.0 3 0 0 3 3 3 1 RasGEF domain RbsD_FucU PF05025.13 PRP79654.1 - 2.9e-29 102.2 0.4 1.8e-28 99.6 0.0 2.7 2 0 0 2 2 2 1 RbsD / FucU transport protein family RasGEF_N PF00618.20 PRP79654.1 - 7.8e-21 74.3 3.6 3.6e-20 72.2 3.6 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF1664 PF07889.12 PRP79654.1 - 0.089 12.8 0.1 6.7 6.8 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) RabGAP-TBC PF00566.18 PRP79654.1 - 0.11 12.1 3.6 0.24 11.0 0.1 2.8 2 1 0 2 2 2 0 Rab-GTPase-TBC domain Asp-B-Hydro_N PF05279.11 PRP79654.1 - 0.93 9.5 18.5 0.75 9.8 12.3 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DAG_kinase_N PF14513.6 PRP79654.1 - 2.9 8.1 10.8 7.6 6.7 0.3 3.0 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Uteroglobin PF01099.17 PRP79654.1 - 5.8 7.3 6.4 9.6 6.6 0.6 3.4 3 0 0 3 3 3 0 Uteroglobin family F-box PF00646.33 PRP79655.1 - 6.6e-07 29.1 0.2 1.4e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP79655.1 - 3.4e-05 23.6 2.1 7e-05 22.6 2.1 1.6 1 0 0 1 1 1 1 F-box-like Glyco_hydro_43 PF04616.14 PRP79656.1 - 4.8e-06 26.1 0.8 0.027 13.8 0.0 2.5 2 1 1 3 3 3 2 Glycosyl hydrolases family 43 PAN_4 PF14295.6 PRP79656.1 - 3.9e-05 23.5 5.1 6.7e-05 22.7 2.3 2.7 3 0 0 3 3 3 1 PAN domain Asparaginase_II PF06089.12 PRP79656.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 L-asparaginase II AAA_16 PF13191.6 PRP79657.1 - 3.3e-40 138.3 0.0 1e-39 136.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain HATPase_c PF02518.26 PRP79657.1 - 2.8e-26 92.2 0.3 7.6e-26 90.8 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP79657.1 - 3e-19 69.2 0.1 6.7e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.25 PRP79657.1 - 6.4e-12 45.4 0.0 2e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain PAS PF00989.25 PRP79657.1 - 2.4e-11 43.6 0.1 7.5e-11 42.0 0.1 1.9 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 PRP79657.1 - 5.3e-11 43.3 0.1 9.9e-08 32.7 0.0 2.8 2 0 0 2 2 2 2 GAF domain PAS_9 PF13426.7 PRP79657.1 - 7.5e-10 39.0 0.1 2.6e-09 37.3 0.1 2.0 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 PRP79657.1 - 1.3e-07 31.5 2.6 7.5e-07 29.1 0.1 2.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 PRP79657.1 - 1.8e-06 28.3 0.0 1.5e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 PRP79657.1 - 0.00072 19.5 0.0 0.0029 17.6 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 PRP79657.1 - 0.0011 19.1 0.0 0.005 17.1 0.0 2.2 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 PRP79657.1 - 0.0089 15.9 0.2 0.024 14.5 0.2 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 PRP79657.1 - 0.031 14.6 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold Kinase-like PF14531.6 PRP79657.1 - 0.043 13.1 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF1664 PF07889.12 PRP79657.1 - 0.046 13.8 1.0 0.11 12.5 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AAA_22 PF13401.6 PRP79657.1 - 0.055 13.7 0.1 0.9 9.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain Methyltransf_32 PF13679.6 PRP79658.1 - 0.021 14.8 0.4 0.43 10.6 0.4 2.6 1 1 0 1 1 1 0 Methyltransferase domain Hema_esterase PF03996.15 PRP79659.1 - 0.13 12.0 0.1 0.23 11.2 0.0 1.4 1 1 0 1 1 1 0 Hemagglutinin esterase tRNA-synt_1b PF00579.25 PRP79660.1 - 1.1e-60 205.5 0.0 1.7e-60 204.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) VGCC_beta4Aa_N PF12052.8 PRP79660.1 - 8.8 6.5 6.2 11 6.3 1.8 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Pro-kuma_activ PF09286.11 PRP79663.1 - 1.2e-18 67.8 0.7 2.2e-18 66.9 0.7 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP79663.1 - 3.1e-08 33.2 0.4 6e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 Subtilase family DNA_pol_E_B PF04042.16 PRP79665.1 - 2.8e-37 128.2 0.0 4.2e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 PRP79665.1 - 1.3e-36 125.5 0.0 2.3e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Pro-MCH PF05824.12 PRP79665.1 - 0.095 12.6 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) EF-hand_5 PF13202.6 PRP79666.1 - 0.13 11.8 0.5 1.3 8.6 0.2 2.2 2 0 0 2 2 2 0 EF hand Pkinase PF00069.25 PRP79667.1 - 2.5e-65 220.5 0.0 4.2e-65 219.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Hydrolase_4 PF12146.8 PRP79667.1 - 3.5e-46 157.4 0.0 4.7e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 PRP79667.1 - 9.7e-39 133.2 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_1 PF00561.20 PRP79667.1 - 4.6e-14 52.7 0.0 8.6e-13 48.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Kinase-like PF14531.6 PRP79667.1 - 1.4e-06 27.9 0.0 2.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Abhydrolase_6 PF12697.7 PRP79667.1 - 3e-06 28.0 0.0 4.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FTA2 PF13095.6 PRP79667.1 - 0.00021 21.0 0.1 0.21 11.2 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PRP79667.1 - 0.0013 17.6 0.3 0.003 16.4 0.3 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP79667.1 - 0.0019 17.6 0.0 0.0045 16.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP79667.1 - 0.023 14.3 0.1 0.87 9.2 0.0 2.3 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 PRP79667.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP79667.1 - 0.09 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DLH PF01738.18 PRP79667.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family CAP PF00188.26 PRP79668.1 - 0.12 13.3 2.4 0.52 11.2 0.2 2.5 1 1 1 2 2 2 0 Cysteine-rich secretory protein family AAA_8 PF12780.7 PRP79670.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 REJ PF02010.15 PRP79672.1 - 7.2e-38 130.5 11.1 7.2e-38 130.5 11.1 4.1 2 2 1 3 3 3 1 REJ domain Ribosomal_S15 PF00312.22 PRP79672.1 - 3.5e-13 49.5 0.2 6.2e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Plasmodium_HRP PF05403.11 PRP79672.1 - 0.17 11.6 0.1 0.32 10.8 0.1 1.3 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) tRNA-synt_2c PF01411.19 PRP79673.1 - 3.5e-220 732.2 0.0 3.5e-220 732.2 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 PRP79673.1 - 1.7e-12 47.2 0.1 3.7e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Activator-TraM PF11657.8 PRP79673.1 - 0.61 9.9 8.3 1.6 8.6 4.8 3.0 3 0 0 3 3 3 0 Transcriptional activator TraM ESP PF16590.5 PRP79673.1 - 1.6 9.1 4.5 8.5 6.7 1.7 3.1 2 1 0 2 2 2 0 Exocrine gland-secreting peptide MMPL PF03176.15 PRP79673.1 - 1.7 7.5 4.5 3.1 6.6 4.5 1.3 1 0 0 1 1 1 0 MMPL family Cation_efflux PF01545.21 PRP79674.1 - 3.4e-45 154.2 30.3 5.4e-45 153.6 30.3 1.3 1 1 0 1 1 1 1 Cation efflux family Voltage_CLC PF00654.20 PRP79674.1 - 0.023 14.0 2.2 0.07 12.4 2.3 1.6 1 1 0 2 2 2 0 Voltage gated chloride channel EIIC-GAT PF03611.14 PRP79674.1 - 0.034 13.2 4.6 0.057 12.5 4.6 1.3 1 0 0 1 1 1 0 PTS system sugar-specific permease component Na_H_Exchanger PF00999.21 PRP79674.1 - 0.32 9.7 12.6 0.65 8.7 7.0 2.2 2 0 0 2 2 2 0 Sodium/hydrogen exchanger family Hid1 PF12722.7 PRP79674.1 - 0.4 8.7 4.5 0.53 8.4 4.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Podoplanin PF05808.11 PRP79674.1 - 0.63 10.1 2.3 1.4 9.0 1.6 2.0 1 1 0 1 1 1 0 Podoplanin Thg1 PF04446.12 PRP79675.1 - 6.6e-29 100.5 0.0 9.7e-29 99.9 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase DUF4085 PF13315.6 PRP79675.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) G-patch PF01585.23 PRP79676.1 - 2.5e-12 46.5 1.3 4.3e-12 45.7 1.3 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PRP79676.1 - 0.00064 19.8 0.5 0.0015 18.6 0.5 1.6 1 0 0 1 1 1 1 G-patch domain PVL_ORF50 PF07768.11 PRP79676.1 - 0.052 13.9 5.2 0.29 11.5 2.5 2.6 2 0 0 2 2 2 0 PVL ORF-50-like family FlxA PF14282.6 PRP79676.1 - 0.3 11.1 3.4 0.64 10.0 3.4 1.5 1 0 0 1 1 1 0 FlxA-like protein Methyltransf_11 PF08241.12 PRP79677.1 - 4.9e-25 88.0 0.1 8.9e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP79677.1 - 1.3e-23 83.5 0.0 3.3e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP79677.1 - 1.5e-22 80.0 0.0 2.4e-22 79.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP79677.1 - 4.6e-18 65.4 0.0 8.5e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PRP79677.1 - 5.8e-16 59.0 0.1 1.8e-15 57.5 0.0 1.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP79677.1 - 3.2e-14 53.1 0.1 1.3e-13 51.2 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP79677.1 - 7.5e-12 45.1 0.0 1.4e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 PRP79677.1 - 7.9e-10 38.6 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 PRP79677.1 - 5.9e-09 35.7 0.0 9.3e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 PRP79677.1 - 5.5e-08 32.5 0.0 9.8e-06 25.1 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_8 PF05148.15 PRP79677.1 - 2.8e-06 27.4 0.4 8.4e-05 22.5 0.1 2.8 2 1 0 2 2 2 1 Hypothetical methyltransferase CMAS PF02353.20 PRP79677.1 - 3.6e-06 26.5 0.1 4.2e-06 26.2 0.1 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 PRP79677.1 - 4.2e-06 25.6 0.0 6.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 PRP79677.1 - 5.1e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 PRP79677.1 - 2.1e-05 24.2 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 PRP79677.1 - 3.8e-05 23.7 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PRP79677.1 - 0.00064 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 PRP79677.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 PRP79677.1 - 0.0018 18.4 0.1 0.015 15.4 0.1 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase UPF0020 PF01170.18 PRP79677.1 - 0.0019 18.0 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PRMT5 PF05185.16 PRP79677.1 - 0.002 18.0 0.3 0.0038 17.1 0.0 1.5 2 0 0 2 2 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.11 PRP79677.1 - 0.0033 16.4 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltr_RsmB-F PF01189.17 PRP79677.1 - 0.0039 16.9 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TehB PF03848.14 PRP79677.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB AlaDh_PNT_C PF01262.21 PRP79677.1 - 0.0084 15.4 0.3 1.7 7.9 0.1 2.9 2 2 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_PK PF05891.12 PRP79677.1 - 0.0089 15.6 0.1 0.022 14.3 0.0 1.7 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 PRP79677.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase GidB PF02527.15 PRP79677.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G LIM PF00412.22 PRP79678.1 - 5.8e-34 116.1 28.4 9.2e-12 45.0 1.1 4.0 4 0 0 4 4 4 3 LIM domain Acetyltransf_13 PF13880.6 PRP79678.1 - 2.7e-27 94.6 0.0 5.5e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 PRP79678.1 - 3.6e-06 26.7 0.1 3.6e-06 26.7 0.1 4.5 5 0 0 5 5 5 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 PRP79678.1 - 2e-05 24.9 0.0 4.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP79678.1 - 0.00017 21.8 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family YopX PF09643.10 PRP79678.1 - 0.002 18.2 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 YopX protein Acetyltransf_10 PF13673.7 PRP79678.1 - 0.0075 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP79678.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rpr2 PF04032.16 PRP79678.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.9 4 1 0 4 4 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-BED PF02892.15 PRP79678.1 - 5.5 7.1 13.8 27 4.9 2.2 4.5 4 1 0 4 4 4 0 BED zinc finger zf-C3HC4_2 PF13923.6 PRP79678.1 - 5.9 6.8 11.2 0.51 10.2 0.3 3.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 PRP79680.1 - 4.1e-50 170.0 0.0 8.9e-50 168.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP79680.1 - 2.8e-32 111.3 0.0 6.7e-30 103.7 0.0 3.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PRP79680.1 - 0.0073 16.6 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain CDC45 PF02724.14 PRP79680.1 - 0.1 10.9 29.2 0.15 10.3 29.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Hormone_3 PF00159.18 PRP79680.1 - 0.17 12.0 0.0 10 6.3 0.0 2.5 2 0 0 2 2 2 0 Pancreatic hormone peptide SOBP PF15279.6 PRP79680.1 - 2.2 8.8 19.2 3.7 8.1 19.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 PRP79680.1 - 2.3 6.8 19.2 3.5 6.2 19.2 1.2 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 PRP79680.1 - 8.4 5.1 21.1 11 4.7 21.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FHA PF00498.26 PRP79681.1 - 5.9e-13 49.0 0.0 1.9e-12 47.3 0.0 2.0 1 0 0 1 1 1 1 FHA domain LemA PF04011.12 PRP79683.1 - 0.077 12.8 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 LemA family DUF2855 PF11017.8 PRP79684.1 - 2.1e-94 317.1 0.9 2.4e-94 316.9 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Di19_C PF14571.6 PRP79684.1 - 0.19 12.3 0.0 0.37 11.3 0.0 1.4 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF2855 PF11017.8 PRP79685.1 - 3.5e-94 316.3 0.6 4.6e-94 315.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Adaptin_N PF01602.20 PRP79687.1 - 3e-146 488.1 19.3 3.7e-146 487.7 19.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PRP79687.1 - 1.5e-61 207.2 12.9 2.1e-61 206.7 1.7 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 PRP79687.1 - 2.5e-18 66.2 0.0 2e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 PRP79687.1 - 4.1e-18 65.6 11.5 5.8e-08 33.0 0.1 6.2 4 1 3 7 7 6 4 HEAT repeats HEAT PF02985.22 PRP79687.1 - 2.8e-14 52.0 6.3 0.0016 18.5 0.1 7.1 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 PRP79687.1 - 8.9e-08 31.9 5.1 0.01 15.9 0.2 4.5 4 0 0 4 4 3 3 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 PRP79687.1 - 7.5e-06 25.3 3.5 0.0025 17.1 0.3 2.6 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 PRP79687.1 - 1.1e-05 25.9 7.8 0.2 12.2 0.1 5.2 5 1 0 5 5 5 2 HEAT-like repeat Alpha_adaptinC2 PF02883.20 PRP79687.1 - 1.1e-05 25.7 0.3 2.7e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 PRP79687.1 - 9.6e-05 22.5 12.0 0.059 13.6 0.1 5.6 2 1 3 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Nipped-B_C PF12830.7 PRP79687.1 - 0.00047 20.2 1.2 4.4 7.2 0.0 3.7 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus UNC45-central PF11701.8 PRP79687.1 - 0.001 19.0 0.6 1.3 9.0 0.0 2.8 2 0 0 2 2 2 2 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 PRP79687.1 - 0.0034 17.0 1.9 6.9 6.2 0.4 3.6 2 2 0 2 2 2 2 CLASP N terminal RasGEF_N_2 PF14663.6 PRP79687.1 - 0.0041 17.5 1.6 0.5 10.8 0.1 4.0 2 2 1 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain SIL1 PF16782.5 PRP79687.1 - 0.22 10.7 3.0 0.54 9.4 1.7 2.3 1 1 1 2 2 2 0 Nucleotide exchange factor SIL1 V-ATPase_H_C PF11698.8 PRP79687.1 - 1.5 9.0 8.2 8.4 6.5 0.0 3.9 5 0 0 5 5 5 0 V-ATPase subunit H ATG22 PF11700.8 PRP79688.1 - 3.1e-75 253.6 17.3 4.8e-75 253.0 17.3 1.3 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 PRP79688.1 - 2.6e-10 39.8 34.7 2.8e-05 23.2 16.9 3.3 2 2 1 3 3 3 3 Major Facilitator Superfamily Chitin_bind_1 PF00187.19 PRP79688.1 - 1.4e-06 28.6 18.7 1.4e-06 28.6 18.7 2.1 2 0 0 2 2 2 1 Chitin recognition protein COesterase PF00135.28 PRP79689.1 - 5.3e-86 289.5 0.1 7.4e-86 289.1 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP79689.1 - 0.00049 20.0 0.3 0.0047 16.8 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ank_2 PF12796.7 PRP79689.1 - 0.068 13.8 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP79689.1 - 0.11 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ABC_tran PF00005.27 PRP79690.1 - 2.4e-21 76.7 0.0 4.8e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 PRP79690.1 - 0.00012 21.7 0.3 0.00021 20.8 0.3 1.4 1 0 0 1 1 1 1 SbmA/BacA-like family RsgA_GTPase PF03193.16 PRP79690.1 - 0.00017 21.5 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PRP79690.1 - 0.00071 19.1 0.2 0.044 13.2 0.2 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 PRP79690.1 - 0.0052 16.7 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.23 PRP79690.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 PRP79690.1 - 0.013 15.8 0.6 0.11 12.8 0.5 2.3 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP79690.1 - 0.018 14.8 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP79690.1 - 0.019 14.7 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP79690.1 - 0.02 15.3 0.1 0.043 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 PRP79690.1 - 0.041 13.6 0.1 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein SLATT_5 PF18160.1 PRP79690.1 - 0.041 13.2 0.1 0.072 12.4 0.1 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 AAA_21 PF13304.6 PRP79690.1 - 0.058 13.2 2.3 0.38 10.5 0.1 2.5 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 PRP79690.1 - 0.061 13.7 0.1 6.5 7.2 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PHR PF08005.12 PRP79690.1 - 0.091 13.4 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 PHR domain Rad17 PF03215.15 PRP79690.1 - 0.093 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 PRP79690.1 - 0.11 11.9 0.3 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein NCD3G PF07562.14 PRP79694.1 - 0.37 10.8 7.4 0.03 14.3 1.0 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUF3784 PF12650.7 PRP79694.1 - 1.6 9.0 8.8 6.5 7.0 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) Pkinase_Tyr PF07714.17 PRP79695.1 - 1.9e-74 250.2 0.0 2.7e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79695.1 - 9.1e-53 179.3 0.0 1.4e-52 178.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP79695.1 - 2.6e-38 129.4 116.1 5.5e-05 23.4 4.4 18.4 11 5 6 19 19 19 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP79695.1 - 5.2e-38 128.6 120.4 8.5e-06 25.4 12.8 16.2 9 3 8 18 18 18 15 Leucine rich repeat Kdo PF06293.14 PRP79695.1 - 0.00017 21.0 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP79695.1 - 0.0003 20.2 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP79695.1 - 0.0025 16.7 0.1 0.0043 15.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_1 PF00560.33 PRP79695.1 - 0.0094 16.4 106.2 0.11 13.1 0.9 25.6 27 4 0 27 27 26 1 Leucine Rich Repeat UFD1 PF03152.14 PRP79695.1 - 0.014 14.9 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Amnionless PF14828.6 PRP79695.1 - 0.063 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Amnionless Orf78 PF06024.12 PRP79695.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) MKT1_C PF12246.8 PRP79695.1 - 0.14 11.4 2.2 14 4.8 0.2 3.1 2 1 1 3 3 3 0 Temperature dependent protein affecting M2 dsRNA replication PIF1 PF05970.14 PRP79697.1 - 8.6e-57 192.9 0.0 1.3e-56 192.4 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 PRP79697.1 - 1.1e-25 90.5 0.0 1.6e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cauli_VI PF01693.16 PRP79697.1 - 3.1e-19 69.0 2.6 7.5e-19 67.8 2.6 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_19 PF13245.6 PRP79697.1 - 6.4e-10 39.5 0.0 2.1e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP79697.1 - 0.00033 20.9 0.0 0.0016 18.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 PRP79697.1 - 0.0008 17.5 0.2 0.026 12.5 0.0 2.1 2 0 0 2 2 2 1 Helicase Viral_helicase1 PF01443.18 PRP79697.1 - 0.0016 18.3 1.3 0.79 9.4 0.0 3.3 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SH3_13 PF18335.1 PRP79697.1 - 0.0089 15.8 1.1 0.06 13.2 0.2 2.6 3 0 0 3 3 2 1 ATP-dependent RecD-like DNA helicase SH3 domain PhoH PF02562.16 PRP79697.1 - 0.013 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.6 PRP79697.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 PRP79697.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Helicase MeaB PF03308.16 PRP79697.1 - 0.034 13.1 0.1 0.068 12.1 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 PRP79697.1 - 0.036 14.4 0.0 0.082 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 PRP79697.1 - 0.092 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 PRP79697.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 PRP79697.1 - 0.17 11.8 0.3 0.8 9.6 0.1 2.2 2 0 0 2 2 2 0 NTPase PseudoU_synth_2 PF00849.22 PRP79698.1 - 6.9e-20 71.7 0.5 9.8e-20 71.2 0.5 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2090 PF09863.9 PRP79698.1 - 0.042 12.9 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Ras PF00071.22 PRP79699.1 - 0.0011 18.6 0.0 0.0034 17.0 0.0 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP79699.1 - 0.0037 17.5 0.0 0.0086 16.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase zf-C2H2_2 PF12756.7 PRP79700.1 - 1.2e-31 109.0 17.1 9.3e-27 93.3 4.2 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PRP79700.1 - 1.9e-08 34.4 22.7 9.4e-06 25.8 4.3 4.4 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP79700.1 - 2.8e-06 27.5 2.9 2.8e-06 27.5 2.9 3.3 4 0 0 4 4 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 PRP79700.1 - 0.00037 20.8 20.9 0.0012 19.2 0.7 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP79700.1 - 0.0076 17.0 16.5 0.3 12.0 0.1 5.2 5 0 0 5 5 5 1 C2H2-type zinc finger AKAP95 PF04988.12 PRP79700.1 - 0.011 16.0 4.9 1.8 8.8 0.1 3.2 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.12 PRP79700.1 - 0.012 15.7 1.4 0.012 15.7 1.4 3.7 3 0 0 3 3 3 0 DBF zinc finger Mut7-C PF01927.16 PRP79700.1 - 0.93 9.6 7.6 1 9.5 2.0 3.0 1 1 1 3 3 3 0 Mut7-C RNAse domain zf-BED PF02892.15 PRP79700.1 - 2.5 8.2 6.5 6 7.0 0.6 3.6 3 0 0 3 3 3 0 BED zinc finger BIR PF00653.21 PRP79700.1 - 2.8 8.7 9.7 15 6.3 0.7 3.7 4 0 0 4 4 4 0 Inhibitor of Apoptosis domain zf-3CxxC PF13695.6 PRP79700.1 - 5 7.7 9.3 0.51 10.8 3.7 2.2 3 0 0 3 3 2 0 Zinc-binding domain zinc_ribbon_4 PF13717.6 PRP79700.1 - 5.3 7.1 6.8 48 4.0 0.9 3.3 3 0 0 3 3 3 0 zinc-ribbon domain Aldo_ket_red PF00248.21 PRP79701.1 - 6e-40 137.3 0.0 2.2e-39 135.5 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 PRP79701.1 - 1.2e-11 44.7 0.1 1.2e-10 41.4 0.0 2.4 3 0 0 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.6 PRP79701.1 - 8.5e-06 25.8 0.1 4.2e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 NAD(P)H-binding GCV_H PF01597.19 PRP79702.1 - 1.4e-39 134.7 0.1 1.8e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 PRP79702.1 - 0.0059 16.4 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Helicase_C PF00271.31 PRP79703.1 - 2e-07 31.3 0.6 4e-07 30.4 0.6 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Asp-B-Hydro_N PF05279.11 PRP79703.1 - 0.0046 17.0 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region FAM60A PF15396.6 PRP79703.1 - 0.048 13.7 3.5 0.074 13.0 3.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SWIRM-assoc_2 PF16496.5 PRP79703.1 - 3.9 6.3 12.3 6.8 5.4 9.1 2.5 2 1 1 3 3 3 0 SWIRM-associated domain at the N-terminal NUDIX PF00293.28 PRP79705.1 - 1.3e-05 25.2 0.1 2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain TPR_2 PF07719.17 PRP79707.1 - 5.8e-07 29.1 11.1 0.0064 16.5 0.5 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_C PF00254.28 PRP79707.1 - 1.2e-06 28.7 0.2 4.6e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 PRP79707.1 - 2.5e-06 27.0 15.6 0.0028 17.4 0.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Pkr1 PF08636.10 PRP79707.1 - 3.4e-06 27.1 0.9 5.6e-06 26.4 0.9 1.3 1 0 0 1 1 1 1 ER protein Pkr1 TPR_19 PF14559.6 PRP79707.1 - 7.5e-06 26.4 5.4 1.7e-05 25.2 2.9 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP79707.1 - 1.1e-05 25.5 0.1 3.2e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP79707.1 - 9.9e-05 22.3 9.0 0.0008 19.4 0.8 2.9 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 PRP79707.1 - 0.00011 22.2 7.1 0.0077 16.4 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP79707.1 - 0.0011 19.5 2.3 0.015 16.1 0.8 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP79707.1 - 0.0026 18.0 3.2 2.6 8.4 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP79707.1 - 0.0067 16.6 2.4 1 9.6 1.0 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2207 PF09972.9 PRP79707.1 - 0.012 14.4 5.1 0.012 14.4 3.6 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TPR_16 PF13432.6 PRP79707.1 - 0.013 16.1 3.1 4.7 7.9 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.10 PRP79707.1 - 0.019 14.0 0.4 0.035 13.1 0.4 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 PRP79707.1 - 0.029 15.0 7.8 0.077 13.7 0.3 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 PRP79707.1 - 0.16 12.3 4.6 0.12 12.7 2.3 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP79707.1 - 0.25 11.0 7.7 0.14 11.9 0.8 3.0 3 1 0 3 3 3 0 TPR repeat DUF262 PF03235.14 PRP79707.1 - 1.7 8.7 12.9 0.31 11.2 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF262 F-box-like PF12937.7 PRP79708.1 - 0.0018 18.2 2.0 0.0084 16.0 2.0 2.2 1 0 0 1 1 1 1 F-box-like LRR_5 PF13306.6 PRP79708.1 - 0.0033 17.4 0.0 1.2 9.1 0.0 3.2 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 PRP79708.1 - 0.18 12.3 21.6 0.93 10.0 3.0 6.5 3 3 5 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP79708.1 - 0.58 10.0 15.7 9.1 6.1 2.6 5.7 3 2 3 6 6 6 0 Leucine rich repeat IL3 PF02059.15 PRP79709.1 - 0.015 15.3 1.9 1 9.4 0.5 2.4 2 0 0 2 2 2 0 Interleukin-3 Mer2 PF09074.10 PRP79709.1 - 0.032 14.1 8.8 0.0089 15.8 5.9 1.6 2 0 0 2 2 2 0 Mer2 Spc7 PF08317.11 PRP79709.1 - 0.072 12.0 14.0 0.065 12.1 8.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TSC22 PF01166.18 PRP79709.1 - 1.7 9.0 14.1 4.3 7.7 3.9 3.9 3 2 1 4 4 4 0 TSC-22/dip/bun family JAKMIP_CC3 PF16034.5 PRP79709.1 - 2.4 8.1 19.4 1.7 8.5 10.8 3.1 1 1 1 2 2 2 0 JAKMIP CC3 domain Exonuc_VII_L PF02601.15 PRP79709.1 - 4.6 6.7 12.1 14 5.1 12.1 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Cauli_AT PF03233.13 PRP79709.1 - 5.4 6.9 8.0 0.68 9.8 1.6 2.4 2 1 1 3 3 3 0 Aphid transmission protein bZIP_1 PF00170.21 PRP79709.1 - 9.3 6.4 13.1 1.4 9.1 1.6 3.1 3 1 0 3 3 3 0 bZIP transcription factor Ras PF00071.22 PRP79710.1 - 1.3e-55 187.4 0.0 1.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79710.1 - 6.8e-23 81.2 0.0 1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP79710.1 - 2.9e-06 26.8 0.0 3.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Pkinase_Tyr PF07714.17 PRP79711.1 - 1.1e-63 214.9 0.0 1.7e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79711.1 - 1.5e-43 149.0 0.0 3.3e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP79711.1 - 9.2e-37 124.6 98.6 8.7e-08 31.8 3.4 13.0 7 4 6 15 15 15 15 Leucine rich repeat LRR_4 PF12799.7 PRP79711.1 - 4.4e-24 84.2 107.0 0.00082 19.7 0.3 17.6 12 4 5 18 18 18 12 Leucine Rich repeats (2 copies) Cellulase PF00150.18 PRP79711.1 - 1.3e-15 57.6 12.4 1.7e-11 44.1 7.4 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) LRR_5 PF13306.6 PRP79711.1 - 0.033 14.1 22.3 0.65 10.0 0.8 4.9 4 1 1 5 5 5 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PRP79711.1 - 0.68 10.7 95.0 3.7 8.5 0.2 21.9 22 1 0 22 22 22 0 Leucine Rich Repeat LRR_9 PF14580.6 PRP79711.1 - 1 8.8 11.0 0.9 9.0 4.2 3.5 3 1 2 5 5 5 0 Leucine-rich repeat Colipase PF01114.18 PRP79712.1 - 0.043 13.5 15.0 0.05 13.3 2.4 2.5 2 0 0 2 2 2 0 Colipase, N-terminal domain Colipase-like PF15083.6 PRP79712.1 - 0.11 12.6 17.2 0.11 12.6 15.4 1.7 1 1 0 1 1 1 0 Colipase-like LEAP-2 PF07359.11 PRP79712.1 - 7.1 6.5 8.2 2.1 8.2 1.2 2.3 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Abhydrolase_6 PF12697.7 PRP79713.1 - 0.045 14.3 0.7 0.16 12.6 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PRP79713.1 - 0.049 13.1 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 PRP79713.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF915 PF06028.11 PRP79713.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) COesterase PF00135.28 PRP79714.1 - 2e-63 215.0 0.3 2.3e-63 214.8 0.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP79714.1 - 1.4e-05 25.0 1.9 0.00071 19.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP79714.1 - 0.057 12.9 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3141 PF11339.8 PRP79714.1 - 0.11 10.9 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Arabino_trans_C PF14896.6 PRP79716.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 EmbC C-terminal domain Flp_N PF03930.14 PRP79718.1 - 0.0032 17.4 0.6 0.0045 16.9 0.6 1.4 1 1 0 1 1 1 1 Recombinase Flp protein N-terminus NRDE-2 PF08424.10 PRP79718.1 - 0.027 13.6 0.4 0.027 13.6 0.4 1.0 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference UPF0128 PF03673.13 PRP79718.1 - 0.054 13.0 0.1 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0128) WD40 PF00400.32 PRP79722.1 - 4.4e-08 33.6 8.5 0.0053 17.6 0.1 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP79722.1 - 0.0015 18.8 0.2 12 6.3 0.0 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP79723.1 - 0.016 16.1 0.0 0.65 11.0 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Thioredoxin PF00085.20 PRP79724.1 - 4.4e-25 87.7 0.0 7.1e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PRP79724.1 - 0.00068 20.1 0.1 0.02 15.4 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PRP79724.1 - 0.0038 17.4 0.0 0.08 13.1 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like FNIP_M PF14637.6 PRP79725.1 - 5.9e-17 62.4 0.1 1.1e-16 61.6 0.1 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 PRP79725.1 - 9.3e-09 35.2 0.0 1.2e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 PRP79725.1 - 0.034 15.1 0.0 0.25 12.3 0.0 2.4 1 1 1 2 2 2 0 Folliculin-interacting protein N-terminus Phage_holin_2_4 PF16082.5 PRP79725.1 - 1.5 8.6 3.7 0.58 9.9 0.6 1.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF3638 PF12340.8 PRP79726.1 - 1.4e-21 76.9 0.0 4.3e-21 75.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) EF-hand_7 PF13499.6 PRP79726.1 - 9.6e-17 61.2 2.1 5.1e-07 30.1 0.4 3.1 2 0 0 2 2 2 2 EF-hand domain pair DUF3645 PF12359.8 PRP79726.1 - 2.7e-15 55.4 0.2 5.7e-15 54.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_6 PF13405.6 PRP79726.1 - 4.3e-13 48.1 2.7 0.01 15.7 0.1 5.0 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 PRP79726.1 - 1.1e-12 46.5 3.1 0.032 13.8 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 PRP79726.1 - 5e-09 35.3 3.3 0.0042 16.5 0.0 3.9 4 0 0 4 4 4 2 EF hand Vps62 PF06101.11 PRP79726.1 - 1.2e-05 23.8 0.0 2.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 EF-hand_8 PF13833.6 PRP79726.1 - 4.9e-05 23.1 2.9 0.62 10.0 0.0 4.2 3 1 1 4 4 4 2 EF-hand domain pair Coilin_N PF15862.5 PRP79726.1 - 0.015 15.1 1.0 0.19 11.5 1.0 2.4 1 1 0 1 1 1 0 Coilin N-terminus CobT PF06213.12 PRP79726.1 - 0.87 8.9 11.2 2 7.7 11.2 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Roughex PF06020.11 PRP79726.1 - 5 6.1 9.1 9.9 5.1 9.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Trypan_PARP PF05887.11 PRP79726.1 - 6.9 6.7 7.1 13 5.7 7.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PBP_sp32 PF07222.12 PRP79726.1 - 8.7 5.7 8.8 26 4.2 8.8 1.8 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FYVE PF01363.21 PRP79727.1 - 6.3e-07 29.4 11.5 1.2e-06 28.6 11.5 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 PRP79727.1 - 0.00048 20.3 8.4 0.0011 19.2 8.4 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger C1_2 PF03107.16 PRP79727.1 - 0.012 15.9 4.7 0.03 14.6 4.7 1.7 1 0 0 1 1 1 0 C1 domain zf-B_box PF00643.24 PRP79727.1 - 0.46 10.7 10.1 0.048 13.8 4.9 2.0 1 1 1 2 2 2 0 B-box zinc finger zf-RRN7 PF11781.8 PRP79727.1 - 1.2 8.9 4.0 0.72 9.6 1.2 2.1 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 YL1 PF05764.13 PRP79728.1 - 6.5e-28 98.5 30.5 6.5e-28 98.5 30.5 2.0 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 PRP79728.1 - 2.5e-12 46.3 0.1 2.5e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain GREB1 PF15782.5 PRP79728.1 - 4.4 4.3 10.0 5.3 4.0 10.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 PRP79728.1 - 5.4 5.6 6.6 6.7 5.3 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIS_M PF07500.14 PRP79729.1 - 1.9e-24 86.3 2.6 1.9e-24 86.3 2.6 2.3 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 PRP79729.1 - 2.4e-20 72.1 5.1 4.6e-20 71.2 5.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 PRP79729.1 - 5.1e-13 48.8 2.8 1.7e-12 47.1 2.8 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain UPF0167 PF03691.14 PRP79729.1 - 0.05 13.4 2.0 0.058 13.2 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) Zn-ribbon_8 PF09723.10 PRP79729.1 - 1.1 9.5 3.8 3.9 7.7 3.8 1.9 1 1 0 1 1 1 0 Zinc ribbon domain CDC27 PF09507.10 PRP79730.1 - 5.3e-35 121.6 67.0 5.1e-33 115.1 67.0 2.0 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Glycolytic PF00274.19 PRP79731.1 - 1.2e-161 537.2 0.0 1.4e-161 537.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Ras PF00071.22 PRP79733.1 - 7e-49 165.5 0.1 8.1e-49 165.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79733.1 - 1.5e-19 70.3 0.0 2.2e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 PRP79733.1 - 4.7e-06 26.3 0.1 1.4e-05 24.8 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 PRP79733.1 - 3.7e-05 23.3 0.1 4.5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP79733.1 - 0.0082 16.1 0.9 1.5 8.7 0.2 2.6 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP79733.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3128 PF11326.8 PRP79735.1 - 3e-06 27.5 1.6 5.2e-06 26.7 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.17 PRP79735.1 - 0.014 15.6 0.6 0.027 14.7 0.6 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Phage_int_SAM_1 PF02899.17 PRP79736.1 - 0.018 15.3 0.1 0.025 14.9 0.1 1.1 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain ATP-synt_ab PF00006.25 PRP79737.1 - 8.4e-108 358.9 0.0 1.3e-107 358.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 PRP79737.1 - 2.8e-41 140.2 0.0 5.2e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 PRP79737.1 - 1.1e-16 61.1 1.8 3.3e-16 59.5 1.8 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain CDC4_D PF16856.5 PRP79738.1 - 0.093 12.6 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain UQ_con PF00179.26 PRP79740.1 - 3.4e-46 156.4 0.2 3.9e-46 156.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PRP79740.1 - 0.0028 17.9 0.1 0.0039 17.5 0.1 1.3 1 0 0 1 1 1 1 RWD domain CdiI_2 PF18593.1 PRP79740.1 - 0.026 15.2 0.4 0.085 13.5 0.1 1.9 2 0 0 2 2 2 0 CdiI immunity protein UEV PF05743.13 PRP79740.1 - 0.047 13.6 0.1 0.09 12.6 0.1 1.5 1 1 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 PRP79740.1 - 0.053 13.2 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UCH PF00443.29 PRP79741.1 - 2.7e-73 246.6 0.2 7e-73 245.3 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.25 PRP79741.1 - 7.4e-64 215.7 0.0 1.9e-63 214.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79741.1 - 6.1e-40 137.1 0.0 1.3e-39 136.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase UCH_1 PF13423.6 PRP79741.1 - 9.1e-16 58.3 13.8 1.9e-09 37.6 0.7 4.5 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PRP79741.1 - 2.1e-10 41.1 1.3 8.4e-10 39.2 0.1 2.9 3 0 0 3 3 3 1 DUSP domain SAE2 PF08573.10 PRP79741.1 - 1.1e-06 29.7 8.4 2.1e-05 25.6 0.6 3.7 2 1 1 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Pkinase_fungal PF17667.1 PRP79741.1 - 1.3e-06 27.5 0.7 3.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP79741.1 - 3.4e-05 23.3 0.0 7.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Tweety PF04906.13 PRP79741.1 - 0.0029 16.3 5.9 0.2 10.3 0.3 2.4 2 0 0 2 2 2 2 Tweety USP7_C2 PF14533.6 PRP79741.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal adh_short PF00106.25 PRP79742.1 - 3.4e-47 160.5 0.1 4.5e-47 160.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP79742.1 - 1.2e-26 93.7 0.0 1.6e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP79742.1 - 8.5e-15 55.1 0.2 1.4e-14 54.4 0.2 1.2 1 0 0 1 1 1 1 KR domain ATP-synt_ab PF00006.25 PRP79742.1 - 0.0053 16.4 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Epimerase PF01370.21 PRP79742.1 - 0.036 13.5 0.1 0.053 13.0 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Limkain-b1 PF11608.8 PRP79742.1 - 0.054 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 THF_DHG_CYH_C PF02882.19 PRP79742.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 PRP79742.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Big_6 PF17936.1 PRP79743.1 - 0.0019 18.4 1.0 0.0073 16.6 1.0 1.9 1 0 0 1 1 1 1 Bacterial Ig domain Stealth_CR1 PF17101.5 PRP79744.1 - 3.3e-08 33.1 1.1 5.5e-08 32.4 1.1 1.4 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Pkinase PF00069.25 PRP79745.1 - 3.2e-14 52.9 0.0 1.6e-12 47.4 0.0 2.6 1 1 1 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 PRP79745.1 - 0.0018 17.6 0.0 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP79745.1 - 0.078 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GBP PF02263.19 PRP79748.1 - 8.9e-41 139.9 0.2 1.8e-40 138.9 0.2 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 PRP79748.1 - 0.0007 19.7 0.0 0.0021 18.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GldM_N PF12081.8 PRP79748.1 - 0.03 14.4 3.5 0.63 10.1 0.0 2.8 2 0 0 2 2 2 0 GldM N-terminal domain CPSF_A PF03178.15 PRP79749.1 - 8.4e-71 238.9 0.0 2.4e-70 237.4 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 PRP79749.1 - 3.6e-33 114.9 0.3 4.5e-25 88.2 0.0 2.7 2 1 1 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40 PF00400.32 PRP79750.1 - 2.6e-20 72.4 5.3 0.00033 21.4 0.1 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP79750.1 - 0.078 13.3 0.2 22 5.4 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP79750.1 - 0.096 11.3 1.3 12 4.4 0.1 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 MIP PF00230.20 PRP79751.1 - 1.5e-64 217.8 17.7 2.3e-64 217.2 17.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein DEAD PF00270.29 PRP79751.1 - 2.1e-49 167.7 0.0 3.6e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP79751.1 - 2e-29 102.2 0.0 3e-28 98.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ABC_tran PF00005.27 PRP79753.1 - 4e-24 85.7 0.3 8.9e-24 84.6 0.3 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 PRP79753.1 - 1.9e-11 43.8 14.1 1.9e-11 43.8 14.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter AAA_21 PF13304.6 PRP79753.1 - 0.00015 21.7 0.4 0.015 15.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PRP79753.1 - 0.0043 17.0 0.1 0.0094 15.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PRP79753.1 - 0.0072 16.1 0.8 0.022 14.5 0.8 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP79753.1 - 0.018 15.5 1.4 0.035 14.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain GATA PF00320.27 PRP79753.1 - 0.029 14.0 5.4 0.033 13.8 3.2 2.4 2 0 0 2 2 2 0 GATA zinc finger AAA_16 PF13191.6 PRP79753.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain dNK PF01712.19 PRP79753.1 - 0.052 13.4 0.1 15 5.4 0.0 3.0 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_22 PF13401.6 PRP79753.1 - 0.073 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PRP79753.1 - 0.085 12.3 0.2 0.17 11.3 0.2 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 PRP79753.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PRP79753.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 PRP79753.1 - 0.19 11.3 0.2 0.32 10.6 0.2 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AWS PF17907.1 PRP79753.1 - 8.4 6.5 7.3 44 4.2 3.0 3.1 2 0 0 2 2 2 0 AWS domain Ku PF02735.16 PRP79754.1 - 1.4e-38 132.7 0.4 2.1e-38 132.1 0.4 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 PRP79754.1 - 1.3e-33 115.7 1.6 1.3e-33 115.7 1.6 3.4 4 0 0 4 4 4 1 Ku C terminal domain like Ku_N PF03731.15 PRP79754.1 - 1.7e-17 63.9 0.5 4e-17 62.7 0.1 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 PRP79754.1 - 3.2e-09 37.4 4.7 8.8e-09 35.9 2.9 2.6 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 PRP79754.1 - 3e-05 24.4 0.2 6.9e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP79754.1 - 0.00048 20.7 0.1 0.016 15.8 0.0 3.2 3 1 0 3 3 3 1 von Willebrand factor type A domain VWA_3 PF13768.6 PRP79754.1 - 0.012 15.6 0.1 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 von Willebrand factor type A domain Pkinase_Tyr PF07714.17 PRP79755.1 - 1.1e-71 241.1 0.0 1.6e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79755.1 - 2.7e-50 171.2 0.0 3.9e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP79755.1 - 0.00073 18.4 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP79755.1 - 0.0027 17.1 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EphA2_TM PF14575.6 PRP79755.1 - 0.13 13.1 0.8 0.41 11.6 0.8 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 PRP79755.1 - 0.15 11.9 0.1 0.38 10.6 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 PRP79755.1 - 0.4 10.6 1.4 1.1 9.2 1.4 1.7 1 0 0 1 1 1 0 Protocadherin GFA PF04828.14 PRP79756.1 - 4.4e-08 33.4 0.2 4.4e-08 33.4 0.2 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HSP70 PF00012.20 PRP79757.1 - 4e-148 494.3 17.4 4e-148 494.3 17.4 2.3 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 PRP79757.1 - 9.5e-10 37.8 3.4 4.5e-09 35.6 0.6 2.6 3 0 0 3 3 3 1 MreB/Mbl protein FtsA PF14450.6 PRP79757.1 - 0.98 9.9 12.4 57 4.2 0.3 4.7 2 2 0 2 2 2 0 Cell division protein FtsA MFS_1 PF07690.16 PRP79758.1 - 9e-34 116.9 34.0 9e-34 116.9 34.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP79758.1 - 8.5e-07 28.2 11.8 8.5e-07 28.2 11.8 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TMEM89 PF15098.6 PRP79758.1 - 0.3 11.2 1.3 9.3 6.4 0.1 2.5 2 0 0 2 2 2 0 TMEM89 protein family AMP-binding PF00501.28 PRP79759.1 - 3.2e-92 309.3 0.0 4.8e-92 308.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP79759.1 - 9.2e-12 45.8 0.0 1.2e-10 42.2 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 PRP79759.1 - 3e-11 42.6 5.8 5.9e-05 22.6 0.2 6.4 6 1 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PRP79759.1 - 1e-06 28.4 9.2 0.0014 18.4 0.4 4.3 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase PP-binding PF00550.25 PRP79759.1 - 0.0027 18.0 0.0 0.0062 16.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site UCH PF00443.29 PRP79760.1 - 2e-41 142.2 2.0 3.5e-41 141.4 2.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP79760.1 - 6.5e-09 35.8 3.1 3.1e-06 27.0 3.1 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 PRP79760.1 - 6.3e-06 25.9 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 PRP79760.1 - 0.011 15.6 1.3 0.034 14.1 1.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Fez1 PF06818.15 PRP79760.1 - 0.42 11.0 15.5 0.016 15.7 8.6 2.1 2 0 0 2 2 2 0 Fez1 Lebercilin PF15619.6 PRP79760.1 - 7.3 6.2 12.2 1.7 8.3 0.1 3.2 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Ribosomal_S27e PF01667.17 PRP79761.1 - 2.6e-28 97.5 3.8 3.3e-28 97.2 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 PRP79761.1 - 0.02 15.3 1.2 0.16 12.4 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) IBR PF01485.21 PRP79761.1 - 0.027 14.7 0.8 0.04 14.1 0.8 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_1 PF14446.6 PRP79761.1 - 0.16 11.9 3.8 0.26 11.2 3.8 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.12 PRP79761.1 - 0.38 10.3 4.7 0.68 9.5 4.7 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding PIP5K PF01504.18 PRP79762.1 - 3.4e-65 220.0 0.4 6.3e-65 219.1 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF520 PF04461.13 PRP79762.1 - 0.084 13.0 0.6 0.35 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF520) DUF1115 PF06544.12 PRP79763.1 - 5.9e-10 39.4 0.2 8.1e-10 39.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) TATR PF03430.13 PRP79763.1 - 0.08 11.3 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator MCU PF04678.13 PRP79764.1 - 8.4e-30 104.2 0.0 1.4e-29 103.4 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial calcium uniporter DUF2721 PF11026.8 PRP79764.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Pkinase PF00069.25 PRP79765.1 - 5.3e-73 245.6 0.0 5.3e-73 245.6 0.0 1.6 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79765.1 - 3.8e-33 114.9 0.0 5.6e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 PRP79765.1 - 9.5e-14 51.5 0.2 2.7e-13 50.1 0.2 1.8 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 PRP79765.1 - 4.5e-10 39.3 4.3 1e-09 38.2 4.3 1.7 1 0 0 1 1 1 1 PBZ domain Kinase-like PF14531.6 PRP79765.1 - 4e-07 29.6 0.0 9.2e-07 28.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PRP79765.1 - 1.3e-06 27.5 1.5 1.4e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP79765.1 - 0.00072 19.0 0.1 0.0068 15.8 0.0 2.4 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP79765.1 - 0.0091 15.6 0.1 0.0091 15.6 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PRP79765.1 - 0.018 14.9 0.1 0.051 13.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 PRP79765.1 - 0.095 12.3 0.1 0.095 12.3 0.1 2.2 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 PRP79765.1 - 0.28 10.7 0.0 0.28 10.7 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 PRP79766.1 - 4.3e-59 200.0 0.0 1e-58 198.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79766.1 - 1.2e-30 106.6 0.0 1.9e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP79766.1 - 9.5e-08 31.7 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP79766.1 - 8.9e-05 21.4 0.0 0.0002 20.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PRP79766.1 - 0.00015 21.7 0.1 0.00058 19.8 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PRP79766.1 - 0.0005 19.2 0.1 0.00087 18.4 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 PRP79766.1 - 0.0067 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP79766.1 - 0.06 12.3 0.3 0.17 10.8 0.3 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Fapy_DNA_glyco PF01149.24 PRP79767.1 - 8.5e-15 55.4 0.0 1.9e-14 54.2 0.0 1.6 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Neil1-DNA_bind PF09292.10 PRP79767.1 - 4e-08 33.1 0.1 7.1e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Endonuclease VIII-like 1, DNA bind H2TH PF06831.14 PRP79767.1 - 0.036 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain TLP-20 PF06088.11 PRP79767.1 - 0.25 11.2 2.3 0.39 10.6 2.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SAP130_C PF16014.5 PRP79767.1 - 0.65 9.0 9.2 0.9 8.6 9.2 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus MCM_bind PF09739.9 PRP79767.1 - 4.7 5.5 6.1 6.4 5.1 6.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 PRP79767.1 - 5.2 6.8 12.5 8 6.2 12.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 PRP79767.1 - 8.9 6.0 18.4 17 5.2 18.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pkinase_Tyr PF07714.17 PRP79768.1 - 1.3e-72 244.2 0.0 1.8e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79768.1 - 9.1e-48 162.9 0.0 1.3e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP79768.1 - 4.5e-10 39.1 36.0 3.6e-05 23.4 1.5 6.3 5 2 2 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 PRP79768.1 - 6.3e-07 29.6 38.7 0.016 15.6 0.0 8.0 6 1 1 7 7 6 4 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PRP79768.1 - 0.0076 16.5 2.3 0.017 15.4 2.3 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Pkinase_fungal PF17667.1 PRP79768.1 - 0.01 14.6 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase TMEM154 PF15102.6 PRP79768.1 - 0.017 15.0 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family Kdo PF06293.14 PRP79768.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chlam_PMP PF02415.17 PRP79768.1 - 0.13 12.8 0.1 0.13 12.8 0.1 12.8 13 1 0 13 13 12 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kinase-like PF14531.6 PRP79768.1 - 0.21 10.9 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like EphA2_TM PF14575.6 PRP79768.1 - 0.48 11.3 2.1 0.47 11.4 0.2 2.0 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain RL11D PF11088.8 PRP79768.1 - 3.2 8.1 8.0 1.4 9.2 2.6 3.3 1 1 1 2 2 2 0 Glycoprotein encoding membrane proteins RL5A and RL6 PGI PF00342.19 PRP79769.1 - 6.4e-243 806.7 1.3 7.2e-243 806.5 1.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase FCD PF07729.12 PRP79769.1 - 0.007 16.8 0.1 0.017 15.6 0.1 1.6 1 0 0 1 1 1 1 FCD domain DUF4473 PF14747.6 PRP79769.1 - 0.058 14.0 0.2 0.27 11.8 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) PASTA PF03793.19 PRP79769.1 - 0.1 12.5 0.0 0.61 10.0 0.0 2.4 2 0 0 2 2 2 0 PASTA domain MAF_flag10 PF01973.18 PRP79769.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF115 FUSC_2 PF13515.6 PRP79770.1 - 2.8e-14 53.3 16.2 2.8e-14 53.3 16.2 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 PRP79770.1 - 1.4e-12 47.0 3.5 1.4e-12 47.0 3.5 2.2 2 0 0 2 2 2 2 Fusaric acid resistance protein family ArAE_2_N PF10337.9 PRP79770.1 - 2.4e-12 46.7 0.4 2.4e-12 46.7 0.4 2.3 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 PRP79770.1 - 1.1e-09 37.7 14.3 4.9e-08 32.2 8.3 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 PRP79770.1 - 2.8e-05 24.1 1.0 5.7e-05 23.0 0.3 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 PRP79770.1 - 0.0019 18.3 1.6 0.0019 18.3 1.6 3.2 2 1 1 3 3 3 1 Aromatic acid exporter family member 1 RTA1 PF04479.13 PRP79771.1 - 1.1e-45 155.8 4.1 1.9e-45 155.0 4.1 1.3 1 0 0 1 1 1 1 RTA1 like protein MIG-14_Wnt-bd PF06664.12 PRP79771.1 - 0.0033 16.7 1.7 0.0033 16.7 1.7 1.9 1 1 1 2 2 2 1 Wnt-binding factor required for Wnt secretion PMP1_2 PF08114.11 PRP79771.1 - 2.4 8.0 10.0 9.1 6.1 2.6 2.8 2 1 0 2 2 2 0 ATPase proteolipid family Ctr PF04145.15 PRP79772.1 - 2.3e-25 89.9 9.0 2.3e-25 89.9 9.0 2.9 3 1 0 3 3 3 1 Ctr copper transporter family MFS_1 PF07690.16 PRP79772.1 - 1.8e-15 56.7 36.9 1.8e-15 56.7 36.9 2.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 PRP79772.1 - 4.5e-14 52.4 3.0 4.5e-14 52.4 3.0 2.7 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 PRP79772.1 - 0.0014 17.5 10.7 0.0014 17.5 10.7 3.1 4 0 0 4 4 4 1 Sugar (and other) transporter DUF962 PF06127.11 PRP79772.1 - 0.84 9.8 3.9 23 5.2 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF962) CGI-121 PF08617.10 PRP79773.1 - 8.9e-23 81.2 0.0 1.6e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Kinase binding protein CGI-121 TIG PF01833.24 PRP79773.1 - 1.4e-09 37.9 1.1 9.3e-09 35.3 1.1 2.2 2 0 0 2 2 2 1 IPT/TIG domain Mito_carr PF00153.27 PRP79774.1 - 3.1e-78 257.8 4.5 3.2e-26 91.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UNC-50 PF05216.13 PRP79774.1 - 0.046 13.3 0.3 4 6.9 0.0 2.3 2 0 0 2 2 2 0 UNC-50 family Laminin_G_3 PF13385.6 PRP79776.1 - 1.1e-19 71.0 5.1 1.1e-19 71.0 5.1 3.3 3 1 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily ASH PF15780.5 PRP79776.1 - 0.00028 21.0 1.9 0.00042 20.5 0.4 2.2 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Laminin_G_2 PF02210.24 PRP79776.1 - 0.0026 18.3 0.4 0.013 16.1 0.1 2.4 3 0 0 3 3 3 1 Laminin G domain GSIII_N PF12437.8 PRP79777.1 - 5.5e-70 234.2 0.2 1.3e-69 232.9 0.1 1.7 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 PRP79777.1 - 7.6e-33 112.9 0.2 2.8e-32 111.1 0.0 2.1 2 0 0 2 2 2 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 PRP79777.1 - 2.4e-18 66.3 0.0 4.3e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Methyltransf_32 PF13679.6 PRP79777.1 - 6.3e-18 65.2 0.2 1.4e-17 64.1 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF4246 PF14033.6 PRP79777.1 - 5e-16 58.9 0.0 1.5e-08 34.2 0.1 3.4 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_3 PF13640.6 PRP79777.1 - 0.002 19.0 0.0 0.0053 17.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_18 PF12847.7 PRP79777.1 - 0.003 17.5 0.1 0.73 9.8 0.0 3.6 4 0 0 4 4 4 1 Methyltransferase domain TspO_MBR PF03073.15 PRP79781.1 - 1.5e-16 60.7 13.2 2.9e-16 59.8 13.2 1.4 1 1 0 1 1 1 1 TspO/MBR family EF-hand_7 PF13499.6 PRP79781.1 - 1.7e-07 31.6 1.4 1.3e-05 25.5 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP79781.1 - 7.3e-07 28.3 0.0 0.029 13.9 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP79781.1 - 1.8e-06 27.4 0.1 0.0057 16.5 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PRP79781.1 - 0.0031 17.3 0.0 0.069 13.0 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain pair DUF5401 PF17380.2 PRP79781.1 - 0.012 13.7 6.9 0.022 12.9 6.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) EF-hand_5 PF13202.6 PRP79781.1 - 0.093 12.3 0.0 0.73 9.4 0.0 2.3 2 0 0 2 2 2 0 EF hand Helicase_C PF00271.31 PRP79782.1 - 9.8e-17 61.3 0.0 2.6e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP79782.1 - 4.6e-12 46.1 0.4 4.6e-12 46.1 0.4 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HA2 PF04408.23 PRP79782.1 - 1.4e-05 25.4 4.0 0.00069 19.9 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) AAA_22 PF13401.6 PRP79782.1 - 8e-05 22.9 0.1 0.00023 21.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PRP79782.1 - 0.015 15.2 0.1 0.093 12.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 PRP79782.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 PRP79782.1 - 0.042 14.2 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 PRP79782.1 - 1.2 8.8 7.2 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ferlin_C PF16165.5 PRP79782.1 - 4.6 7.2 6.4 9.2 6.2 6.4 1.4 1 0 0 1 1 1 0 Ferlin C-terminus IPK PF03770.16 PRP79783.1 - 6.4e-49 166.5 0.0 9.7e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase ATP-synt_DE_N PF02823.16 PRP79784.1 - 1.6e-16 60.0 0.5 2.2e-16 59.5 0.5 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Voltage_CLC PF00654.20 PRP79785.1 - 1.5e-79 267.8 22.8 2.3e-79 267.2 22.8 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 PRP79785.1 - 0.0062 17.0 0.0 0.08 13.4 0.0 2.5 2 0 0 2 2 2 1 CBS domain DUF3368 PF11848.8 PRP79785.1 - 0.16 11.8 0.2 3.8 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) DDE_Tnp_4 PF13359.6 PRP79786.1 - 0.00021 21.0 0.0 0.00023 20.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HA PF03457.14 PRP79789.1 - 9.2e-15 54.7 0.1 7.5e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Helicase associated domain UBX PF00789.20 PRP79789.1 - 0.0037 17.4 0.2 0.74 10.1 0.0 2.7 3 0 0 3 3 3 2 UBX domain Actin PF00022.19 PRP79790.1 - 1e-149 498.6 0.0 2.3e-149 497.5 0.0 1.6 1 1 0 1 1 1 1 Actin PP2C PF00481.21 PRP79790.1 - 2.4e-60 204.4 0.5 2.4e-60 204.4 0.5 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Ras PF00071.22 PRP79790.1 - 1.6e-53 180.6 0.5 3.2e-53 179.7 0.5 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79790.1 - 3.4e-17 62.8 0.0 8.7e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Anoctamin PF04547.12 PRP79790.1 - 4.9e-12 45.4 17.9 4.5e-11 42.2 18.4 2.0 1 1 0 1 1 1 1 Calcium-activated chloride channel Arf PF00025.21 PRP79790.1 - 7.9e-09 35.2 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family TMC PF07810.13 PRP79790.1 - 8.9e-09 35.9 0.3 3.9e-08 33.9 0.3 2.2 1 0 0 1 1 1 1 TMC domain GTP_EFTU PF00009.27 PRP79790.1 - 0.00026 20.6 0.0 0.00063 19.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP79790.1 - 0.00045 20.2 0.0 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 PRP79790.1 - 0.035 13.7 0.1 0.083 12.4 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Sulf_transp PF04143.14 PRP79790.1 - 0.49 9.9 8.0 0.27 10.7 4.2 2.4 2 1 0 2 2 2 0 Sulphur transport SASA PF03629.18 PRP79793.1 - 1.3e-11 44.6 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase RCC1 PF00415.18 PRP79794.1 - 1.8e-38 130.9 10.3 5.7e-09 36.5 0.0 7.9 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP79794.1 - 4.3e-30 102.8 33.9 1e-08 34.7 1.2 8.0 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 PRP79794.1 - 0.095 12.6 0.0 21 5.1 0.0 2.6 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain TPR_2 PF07719.17 PRP79795.1 - 1.2e-07 31.3 4.5 0.0034 17.4 0.9 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat Palm_thioest PF02089.15 PRP79795.1 - 3.1e-07 30.5 0.0 6.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase TPR_1 PF00515.28 PRP79795.1 - 1.2e-06 28.1 1.9 0.013 15.2 0.9 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Ank_2 PF12796.7 PRP79795.1 - 1.8e-06 28.4 0.0 3.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79795.1 - 6.7e-06 26.5 0.0 1.6e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP79795.1 - 1.4e-05 25.3 0.0 3.5e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Abhydrolase_1 PF00561.20 PRP79795.1 - 7.6e-05 22.5 0.0 0.17 11.5 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 PRP79795.1 - 0.00019 21.2 0.3 0.00036 20.3 0.3 1.3 1 0 0 1 1 1 1 PGAP1-like protein Ank_3 PF13606.6 PRP79795.1 - 0.0025 18.2 0.0 0.0092 16.4 0.0 2.0 2 0 0 2 2 1 1 Ankyrin repeat DUF676 PF05057.14 PRP79795.1 - 0.0044 16.5 0.1 0.0097 15.4 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_12 PF13424.6 PRP79795.1 - 0.015 15.5 1.0 0.4 11.0 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 PRP79795.1 - 0.021 15.2 0.3 0.078 13.4 0.3 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP79795.1 - 0.021 15.3 0.0 0.065 13.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_transf_9 PF01075.17 PRP79795.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Abhydrolase_6 PF12697.7 PRP79795.1 - 0.095 13.3 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank PF00023.30 PRP79795.1 - 0.098 13.1 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Fis1_TPR_C PF14853.6 PRP79795.1 - 0.1 12.7 0.1 0.74 9.9 0.1 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 PRP79795.1 - 0.16 12.8 0.1 35 5.6 0.0 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Cyclin_N PF00134.23 PRP79796.1 - 1.3e-05 24.9 0.1 3.2e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ras PF00071.22 PRP79797.1 - 1.4e-54 184.1 0.0 2.9e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 Ras family Y_phosphatase3 PF13350.6 PRP79797.1 - 1.5e-43 149.5 0.2 1.6e-42 146.1 0.2 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Roc PF08477.13 PRP79797.1 - 1.4e-21 76.9 0.0 4e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP79797.1 - 1.7e-08 34.1 0.0 3.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Y_phosphatase2 PF03162.13 PRP79797.1 - 1.6e-05 24.6 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 PRP79797.1 - 0.00035 20.2 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GTP_EFTU PF00009.27 PRP79797.1 - 0.0043 16.6 0.5 0.017 14.7 0.0 2.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain E1_4HB PF16191.5 PRP79797.1 - 0.024 14.8 0.1 0.41 10.9 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle Myotub-related PF06602.14 PRP79797.1 - 0.038 12.9 0.0 0.079 11.9 0.0 1.4 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Ank_2 PF12796.7 PRP79798.1 - 3.8e-06 27.4 0.4 0.032 14.8 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79798.1 - 5.3e-05 23.7 0.2 0.0019 18.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP79798.1 - 0.00086 19.6 3.4 1.9 8.9 0.2 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP79798.1 - 0.022 15.3 3.1 31 5.6 0.0 4.1 5 0 0 5 5 5 0 Ankyrin repeat Ank PF00023.30 PRP79798.1 - 0.89 10.1 4.0 47 4.7 0.0 4.0 3 1 0 3 3 3 0 Ankyrin repeat VASt PF16016.5 PRP79799.1 - 3.9e-32 111.8 0.1 7.2e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 PRP79799.1 - 7.4e-18 64.5 1.0 1.4e-17 63.6 0.5 1.8 2 0 0 2 2 2 1 GRAM domain YjbR PF04237.13 PRP79799.1 - 0.18 12.4 0.3 3.2 8.4 0.0 2.7 2 1 0 2 2 2 0 YjbR Asp-B-Hydro_N PF05279.11 PRP79799.1 - 1.4 8.9 11.6 0.3 11.1 5.0 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF383 PF04063.14 PRP79800.1 - 1.4e-31 109.7 0.0 1e-30 106.8 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 PRP79800.1 - 8.2e-15 54.4 2.2 1.1e-13 50.7 0.5 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF3361 PF11841.8 PRP79800.1 - 0.0014 18.6 0.3 0.0036 17.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) RRP7 PF12923.7 PRP79800.1 - 0.43 10.7 3.1 0.78 9.9 3.1 1.4 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain KR PF08659.10 PRP79801.1 - 9.7e-05 22.4 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 PRP79801.1 - 0.00039 19.9 0.1 0.0011 18.5 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 PRP79801.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Melibiase_2 PF16499.5 PRP79802.1 - 1.5e-63 214.6 5.1 2.6e-63 213.9 5.1 1.4 1 0 0 1 1 1 1 Alpha galactosidase A RicinB_lectin_2 PF14200.6 PRP79802.1 - 1.6e-21 76.8 4.7 1.9e-11 44.5 0.0 3.8 3 1 2 5 5 5 3 Ricin-type beta-trefoil lectin domain-like Melibiase_C PF17801.1 PRP79802.1 - 2.6e-13 49.8 0.1 1.2e-11 44.4 0.0 2.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 PRP79802.1 - 4.1e-08 32.6 0.0 8.5e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 PRP79802.1 - 0.0091 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain PRiA4_ORF3 PF07929.11 PRP79804.1 - 3e-08 33.6 0.0 3.6e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Pkinase_Tyr PF07714.17 PRP79805.1 - 9.3e-61 205.4 0.0 1.5e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Copine PF07002.16 PRP79805.1 - 5.5e-55 186.2 0.0 8.6e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 Copine Pkinase PF00069.25 PRP79805.1 - 2.3e-38 132.1 0.0 3.9e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP79805.1 - 8e-26 89.9 0.0 4.2e-13 49.2 0.0 3.1 2 0 0 2 2 2 2 SH2 domain C2 PF00168.30 PRP79805.1 - 1.4e-19 70.2 0.1 3e-11 43.5 0.0 3.8 3 0 0 3 3 3 2 C2 domain Cbl_N2 PF02761.14 PRP79805.1 - 2.6e-06 28.0 0.3 1.7e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 PF02762.14 PRP79805.1 - 1.4e-05 24.8 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 CBL proto-oncogene N-terminus, SH2-like domain Kdo PF06293.14 PRP79805.1 - 0.005 16.2 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH2_2 PF14633.6 PRP79805.1 - 0.02 14.3 0.0 0.089 12.2 0.0 1.9 2 0 0 2 2 2 0 SH2 domain Kinase-like PF14531.6 PRP79805.1 - 0.032 13.6 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like IBP39 PF11422.8 PRP79805.1 - 0.036 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Initiator binding protein 39 kDa vWA-TerF-like PF10138.9 PRP79805.1 - 0.038 14.1 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 vWA found in TerF C terminus Y_phosphatase3 PF13350.6 PRP79807.1 - 1e-40 140.2 0.0 1.5e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 PRP79807.1 - 2.9e-09 36.7 0.1 4.5e-07 29.6 0.1 2.6 2 1 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.27 PRP79807.1 - 0.00068 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BLM10_mid PF16507.5 PRP79808.1 - 6.4e-41 140.6 5.8 9.9e-27 93.8 0.1 4.8 2 1 0 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 PRP79808.1 - 4e-26 90.8 0.0 7.5e-25 86.7 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) LRR_8 PF13855.6 PRP79809.1 - 3.6e-12 45.9 21.3 8.7e-08 31.8 7.7 4.0 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PRP79809.1 - 2.2e-07 31.1 21.0 0.0021 18.4 5.3 4.7 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP79809.1 - 7.4e-06 25.8 24.6 0.18 12.4 1.4 7.7 8 0 0 8 8 8 3 Leucine Rich Repeat EMP70 PF02990.16 PRP79812.1 - 5.1e-50 170.6 16.4 5.1e-50 170.6 16.4 1.8 2 0 0 2 2 2 1 Endomembrane protein 70 DUF2070 PF09843.9 PRP79812.1 - 0.39 9.0 12.2 0.5 8.6 12.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Voltage_CLC PF00654.20 PRP79813.1 - 1.2e-63 215.5 31.3 2.8e-63 214.3 26.2 3.1 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PRP79813.1 - 1.2e-19 70.5 1.9 1.4e-08 35.0 0.0 2.8 2 0 0 2 2 2 2 CBS domain DUF1294 PF06961.13 PRP79813.1 - 0.14 12.4 0.4 0.45 10.8 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Ca_hom_mod PF14798.6 PRP79813.1 - 0.14 11.2 0.3 0.96 8.5 0.0 2.4 3 0 0 3 3 3 0 Calcium homeostasis modulator EF-hand_6 PF13405.6 PRP79814.1 - 0.031 14.2 0.8 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Ribosomal_L36 PF00444.18 PRP79815.1 - 1.7e-12 47.3 5.6 4e-12 46.1 5.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L36 JHD PF17811.1 PRP79815.1 - 2.3e-11 44.1 0.0 5.7e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 PRP79815.1 - 2.2e-10 40.3 8.5 2.2e-10 40.3 8.5 3.3 3 0 0 3 3 3 1 PHD-finger JmjC PF02373.22 PRP79815.1 - 1.3e-05 25.6 0.1 0.00022 21.6 0.1 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 PRP79815.1 - 4.1e-05 23.4 1.0 0.00018 21.3 0.3 2.2 1 1 0 2 2 2 1 Cupin-like domain PHD_2 PF13831.6 PRP79815.1 - 0.22 11.1 1.9 0.57 9.8 1.9 1.8 1 0 0 1 1 1 0 PHD-finger FMO-like PF00743.19 PRP79816.1 - 6.7e-45 153.5 2.0 3e-35 121.7 0.1 3.8 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 PRP79816.1 - 9.5e-06 25.8 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 PRP79816.1 - 8.4e-05 21.9 0.4 0.025 13.7 0.1 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 PRP79816.1 - 0.00015 21.1 0.0 0.00068 19.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP79816.1 - 0.001 18.4 0.6 0.16 11.2 0.0 3.5 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP79816.1 - 0.0026 17.8 0.1 0.1 12.6 0.0 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding Cytochrom_B562 PF07361.11 PRP79816.1 - 0.016 15.9 1.8 0.55 10.9 0.3 2.3 2 0 0 2 2 2 0 Cytochrome b562 Thi4 PF01946.17 PRP79816.1 - 0.049 12.9 0.1 0.14 11.3 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Sod_Cu PF00080.20 PRP79817.1 - 1.8e-42 144.9 5.5 3.7e-42 143.9 5.1 1.7 2 0 0 2 2 1 1 Copper/zinc superoxide dismutase (SODC) Paf1 PF03985.13 PRP79817.1 - 0.025 13.6 16.4 0.013 14.5 14.3 1.6 2 0 0 2 2 2 0 Paf1 Nop14 PF04147.12 PRP79817.1 - 0.031 12.5 13.5 0.048 11.9 13.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 PRP79817.1 - 0.11 11.5 8.9 1.7 7.5 7.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.12 PRP79817.1 - 0.11 12.8 5.4 0.21 11.8 5.4 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.14 PRP79817.1 - 0.11 10.8 14.7 0.17 10.1 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 PRP79817.1 - 0.13 10.8 6.2 0.32 9.5 6.2 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 EOS1 PF12326.8 PRP79817.1 - 0.19 11.6 1.7 0.44 10.5 0.9 1.9 2 0 0 2 2 2 0 N-glycosylation protein CobT PF06213.12 PRP79817.1 - 0.3 10.4 16.6 0.49 9.8 16.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Spore_coat_CotO PF14153.6 PRP79817.1 - 0.5 10.3 16.2 1 9.3 16.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.17 PRP79817.1 - 0.71 10.0 2.8 1.5 8.9 2.8 1.5 1 0 0 1 1 1 0 DDHD domain Merozoite_SPAM PF07133.11 PRP79817.1 - 0.78 9.7 30.2 1.5 8.8 30.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF4820 PF16091.5 PRP79817.1 - 0.82 9.0 6.4 1.6 8.0 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 PRP79817.1 - 1.2 8.9 19.8 2.2 8.1 19.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.8 PRP79817.1 - 1.8 8.6 6.4 2.4 8.2 5.3 1.7 2 0 0 2 2 1 0 Replication protein C C-terminal region DUF1115 PF06544.12 PRP79817.1 - 2.7 8.1 8.7 31 4.7 6.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) DNA_pol_phi PF04931.13 PRP79817.1 - 4.6 5.2 18.3 8 4.4 18.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 PRP79817.1 - 4.7 7.4 9.9 9.3 6.4 9.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF740 PF05340.12 PRP79817.1 - 5.3 5.7 11.2 8.6 5.0 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) RNA_pol_Rpc4 PF05132.14 PRP79817.1 - 8.3 6.8 11.2 17 5.8 11.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 COG7 PF10191.9 PRP79818.1 - 9.1e-144 480.6 12.7 4.1e-143 478.4 12.7 1.8 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) NPV_P10 PF05531.12 PRP79818.1 - 0.0096 16.4 0.7 7.4 7.1 0.7 4.4 3 2 0 3 3 3 1 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PRP79818.1 - 0.43 10.6 2.8 3.1 7.8 1.2 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 PRP79819.1 - 7.3e-23 80.9 2.3 7.3e-23 80.9 2.3 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Knl1_RWD_C PF18210.1 PRP79819.1 - 0.0011 19.4 0.4 0.059 13.9 0.0 2.9 3 0 0 3 3 3 1 Knl1 RWD C-terminal domain KapB PF08810.10 PRP79819.1 - 1.5 9.1 3.8 0.83 9.9 0.5 2.2 2 0 0 2 2 2 0 Kinase associated protein B Transposase_mut PF00872.18 PRP79820.1 - 3e-05 23.1 0.2 3e-05 23.1 0.2 2.2 3 0 0 3 3 3 1 Transposase, Mutator family Peptidase_M1 PF01433.20 PRP79821.1 - 4.1e-81 271.7 1.1 6.5e-81 271.1 1.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 PRP79821.1 - 7.2e-63 213.0 0.2 7.2e-63 213.0 0.2 2.0 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PRP79821.1 - 1.7e-43 149.0 0.2 1.1e-42 146.3 0.1 2.3 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain DUF4224 PF13986.6 PRP79821.1 - 0.016 15.1 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) GSHPx PF00255.19 PRP79822.1 - 3.7e-44 148.7 0.2 4.9e-44 148.3 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 PRP79822.1 - 1.7e-05 24.6 0.0 7.5e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 PRP79822.1 - 3.8e-05 23.6 0.0 0.00013 21.9 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family CBM_1 PF00734.18 PRP79822.1 - 2.5 8.1 4.8 0.49 10.4 0.5 1.9 2 0 0 2 2 2 0 Fungal cellulose binding domain CoaE PF01121.20 PRP79823.1 - 8.9e-35 120.0 2.5 8.7e-32 110.2 2.5 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.6 PRP79823.1 - 5.2e-05 23.6 0.1 0.00019 21.7 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PRP79823.1 - 0.0062 16.3 0.1 0.012 15.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 PRP79823.1 - 0.053 14.1 0.1 0.16 12.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 PRP79823.1 - 0.071 12.5 0.7 0.17 11.3 0.1 1.9 1 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 PRP79823.1 - 0.092 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Diphtheria_C PF02763.14 PRP79823.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, C domain GAF PF01590.26 PRP79824.1 - 3e-42 144.4 0.0 5.2e-24 85.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain Guanylate_cyc PF00211.20 PRP79824.1 - 1.2e-40 139.1 0.4 4e-40 137.4 0.1 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain GAF_3 PF13492.6 PRP79824.1 - 6.6e-25 87.9 0.0 3.8e-12 46.7 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 PRP79824.1 - 2.3e-24 86.3 0.0 4.5e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 GAF domain DUF3369 PF11849.8 PRP79824.1 - 7.7e-05 23.0 0.6 0.36 11.0 0.1 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF3369) PAS PF00989.25 PRP79824.1 - 9e-05 22.4 0.1 0.00086 19.3 0.0 2.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 PRP79824.1 - 9.7e-05 22.6 0.7 0.0016 18.6 0.1 3.4 5 0 0 5 5 5 1 PAS domain TPR_2 PF07719.17 PRP79824.1 - 0.0017 18.3 0.1 0.0056 16.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat dCache_1 PF02743.18 PRP79824.1 - 0.0045 16.8 1.0 0.68 9.7 0.0 3.1 3 0 0 3 3 3 1 Cache domain DUF2111 PF09884.9 PRP79824.1 - 0.12 12.5 0.1 60 3.8 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2111) 3Beta_HSD PF01073.19 PRP79825.1 - 3.7e-65 219.7 0.0 4.7e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PRP79825.1 - 1.7e-38 132.5 0.0 2.3e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP79825.1 - 3.8e-17 62.7 0.0 9e-14 51.6 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PRP79825.1 - 1.3e-15 57.2 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 PRP79825.1 - 5.8e-15 55.7 0.0 8.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PRP79825.1 - 1.2e-12 47.5 0.1 2.1e-10 40.2 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 PRP79825.1 - 2.7e-07 30.0 0.1 1.1e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 PRP79825.1 - 0.0033 17.0 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 PRP79825.1 - 0.012 15.6 0.1 0.23 11.4 0.1 2.3 1 1 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 PRP79825.1 - 0.022 15.0 0.3 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 PRP79825.1 - 0.04 14.4 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Rotamase PF00639.21 PRP79829.1 - 2.3e-22 79.7 0.3 3.9e-22 79.0 0.3 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PRP79829.1 - 1.2e-20 74.2 0.4 1.6e-20 73.8 0.4 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 PRP79829.1 - 1.1e-10 41.4 2.3 1.1e-10 41.4 2.3 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 PRP79829.1 - 0.0092 16.8 0.0 0.013 16.3 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 PRP79829.1 - 0.077 13.7 0.2 0.18 12.5 0.0 1.7 2 0 0 2 2 2 0 X8 domain GATA PF00320.27 PRP79830.1 - 3.2e-13 49.0 3.1 3.2e-13 49.0 3.1 2.4 3 0 0 3 3 3 1 GATA zinc finger DZR PF12773.7 PRP79830.1 - 0.0085 16.1 5.0 0.055 13.5 1.1 2.5 2 0 0 2 2 2 1 Double zinc ribbon Vps36-NZF-N PF16988.5 PRP79830.1 - 4.9 6.6 5.8 0.31 10.5 0.3 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Myosin_head PF00063.21 PRP79831.1 - 1.9e-240 799.7 2.0 2.7e-240 799.2 2.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 PRP79831.1 - 4.4e-16 59.0 0.1 3.4e-15 56.2 0.0 2.7 2 0 0 2 2 2 1 DIL domain Spc7 PF08317.11 PRP79831.1 - 0.045 12.6 41.7 0.17 10.8 26.2 3.7 2 1 2 4 4 4 0 Spc7 kinetochore protein AAA_22 PF13401.6 PRP79831.1 - 0.073 13.3 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 PRP79831.1 - 0.075 12.8 0.0 17 5.1 0.0 2.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 PRP79831.1 - 0.089 13.2 0.0 0.089 13.2 0.0 3.8 3 1 0 3 3 2 0 AAA ATPase domain TsaE PF02367.17 PRP79831.1 - 0.093 12.7 0.5 2 8.5 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Hpr_kinase_C PF07475.12 PRP79831.1 - 0.096 12.2 0.1 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SlyX PF04102.12 PRP79831.1 - 0.61 10.8 12.7 42 4.8 0.8 4.7 2 1 1 3 3 3 0 SlyX Fib_alpha PF08702.10 PRP79831.1 - 3.1 8.0 17.6 0.17 12.1 1.6 4.5 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 PRP79831.1 - 8.4 6.8 43.5 0.48 10.9 18.5 3.1 1 1 1 2 2 2 0 Fez1 zf_CCCH_4 PF18345.1 PRP79832.1 - 9e-17 60.5 29.2 5.6e-06 26.2 2.1 3.5 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 PRP79832.1 - 1.5e-14 53.5 21.4 3.8e-05 23.5 3.1 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PRP79832.1 - 7.7e-14 51.1 23.2 0.00024 20.8 0.4 3.8 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 PRP79832.1 - 1e-06 29.4 12.3 0.0027 18.4 0.5 3.2 2 1 1 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 PRP79832.1 - 5e-05 23.6 29.1 0.0052 17.2 3.0 3.8 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 PRP79832.1 - 0.00016 21.8 15.3 0.03 14.5 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger containing family zf-RING_UBOX PF13445.6 PRP79832.1 - 0.00018 21.4 5.2 0.00018 21.4 5.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PRP79832.1 - 0.00064 20.0 5.1 0.00064 20.0 5.1 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP79832.1 - 0.00071 19.4 5.4 0.00071 19.4 5.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 PRP79832.1 - 0.0014 18.5 1.6 0.0014 18.5 1.6 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 PRP79832.1 - 0.0032 17.3 6.6 0.0032 17.3 6.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP79832.1 - 0.0052 16.7 5.5 0.0052 16.7 5.5 2.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 PRP79832.1 - 0.0074 16.0 7.0 0.0074 16.0 7.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 PRP79832.1 - 0.34 11.1 7.2 4.8 7.4 7.3 2.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Gliadin PF13016.6 PRP79832.1 - 3.7 8.0 10.4 1.3 9.5 5.8 2.3 2 1 0 2 2 2 0 Cys-rich Gliadin N-terminal Paf1 PF03985.13 PRP79833.1 - 1.6e-50 172.4 0.4 2.2e-50 171.9 0.4 1.1 1 0 0 1 1 1 1 Paf1 DAGAT PF03982.13 PRP79834.1 - 1.1e-33 116.4 0.0 3.5e-33 114.8 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DNA_pol_B_2 PF03175.13 PRP79834.1 - 2.4e-07 30.0 8.6 5.9e-07 28.7 8.6 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral Biliv-reduc_cat PF09166.10 PRP79834.1 - 0.098 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Biliverdin reductase, catalytic MIP-T3 PF10243.9 PRP79835.1 - 0.049 13.6 0.1 0.068 13.1 0.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain CBFD_NFYB_HMF PF00808.23 PRP79837.1 - 0.17 12.2 1.3 0.22 11.8 0.1 2.0 2 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L44 PF00935.19 PRP79838.1 - 7.5e-36 122.5 12.3 1.1e-35 121.9 12.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 PRP79838.1 - 0.024 14.9 1.1 0.048 14.0 1.1 1.4 1 0 0 1 1 1 0 Cathelicidin DnaJ-X PF14308.6 PRP79839.1 - 0.0074 15.8 0.6 0.0074 15.8 0.6 1.4 2 0 0 2 2 2 1 X-domain of DnaJ-containing Fis1_TPR_C PF14853.6 PRP79839.1 - 0.01 15.9 1.7 0.021 14.9 0.4 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat DUF4533 PF15047.6 PRP79839.1 - 0.017 14.7 0.6 0.022 14.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF2951 PF11166.8 PRP79839.1 - 0.043 14.0 1.2 0.043 14.0 1.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) HARE-HTH PF05066.13 PRP79839.1 - 0.062 13.7 0.4 0.096 13.1 0.4 1.3 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain U1snRNP70_N PF12220.8 PRP79839.1 - 0.067 13.8 1.1 0.077 13.6 0.4 1.5 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DCB PF16213.5 PRP79839.1 - 0.12 12.0 1.5 0.5 10.0 0.7 1.9 1 1 1 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 ADH_zinc_N PF00107.26 PRP79840.1 - 1.4e-14 54.2 0.0 2.7e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP79840.1 - 9.8e-07 29.9 0.1 2.9e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP79840.1 - 0.00097 19.0 0.1 0.0061 16.4 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Metallophos PF00149.28 PRP79841.1 - 3.1e-08 34.4 0.2 6.4e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cytochrom_B561 PF03188.16 PRP79841.1 - 2.1e-07 31.1 13.2 2.3e-07 31.0 10.8 2.4 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Metallophos_2 PF12850.7 PRP79841.1 - 5.5e-07 29.9 0.0 1.7e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PGG PF13962.6 PRP79841.1 - 1.7 8.5 5.0 0.47 10.3 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DOPA_dioxygen PF08883.11 PRP79842.1 - 1.1e-35 122.0 0.4 1.9e-35 121.3 0.2 1.5 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family MepB PF08877.10 PRP79842.1 - 0.11 12.1 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 MepB protein Ank_2 PF12796.7 PRP79844.1 - 1.5e-08 35.1 0.0 2.8e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79844.1 - 5.8e-07 29.9 0.0 5e-06 27.0 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP79844.1 - 4.1e-05 23.8 0.0 0.053 13.9 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP79844.1 - 0.00029 21.0 0.0 1.4 9.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 PRP79844.1 - 0.0033 17.8 0.0 0.85 10.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat VIT PF08487.10 PRP79845.1 - 2.1e-30 105.2 0.2 6.6e-30 103.6 0.2 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PRP79845.1 - 1.6e-22 80.1 0.0 4.2e-22 78.7 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 PRP79845.1 - 8.9e-14 52.1 0.0 3.4e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 PRP79845.1 - 6.7e-10 38.7 0.4 6.5e-09 35.6 0.1 2.7 3 0 0 3 3 3 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 PRP79845.1 - 8e-08 32.9 0.0 5.5e-07 30.2 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PRP79845.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein DUF2201 PF09967.9 PRP79845.1 - 0.031 14.4 0.0 0.4 10.8 0.0 2.8 2 1 0 2 2 2 0 VWA-like domain (DUF2201) CobT_C PF11775.8 PRP79845.1 - 0.082 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Mito_carr PF00153.27 PRP79847.1 - 9.8e-60 198.5 0.2 9.3e-20 70.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Hexapep PF00132.24 PRP79848.1 - 9.6e-15 53.7 13.1 4.9e-07 29.2 3.2 3.8 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PRP79848.1 - 3.1e-05 23.6 13.3 0.003 17.3 0.9 3.2 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase CCDC92 PF14916.6 PRP79848.1 - 0.06 13.1 0.5 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function DUF4954 PF16314.5 PRP79848.1 - 0.19 9.8 0.6 0.27 9.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Sulfate_transp PF00916.20 PRP79849.1 - 4.8e-105 351.4 20.7 6.9e-105 350.9 20.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PRP79849.1 - 2.1e-18 66.1 0.0 7.9e-18 64.2 0.0 1.9 2 0 0 2 2 2 1 STAS domain Ras PF00071.22 PRP79850.1 - 3.7e-49 166.4 0.0 4.5e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79850.1 - 2.3e-30 105.2 0.0 8.5e-30 103.4 0.0 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP79850.1 - 1.5e-11 44.0 0.0 2.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 PRP79850.1 - 0.00042 20.7 0.1 0.0033 17.8 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 PRP79850.1 - 0.00087 19.4 0.0 0.0014 18.7 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP79850.1 - 0.012 14.9 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PRP79850.1 - 0.017 15.0 0.1 0.62 9.9 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 PRP79850.1 - 0.02 14.6 0.1 0.037 13.8 0.1 1.6 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 PRP79850.1 - 0.024 14.2 0.5 0.14 11.7 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 PRP79850.1 - 0.026 14.0 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 PRP79850.1 - 0.082 13.3 0.1 0.19 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 PRP79850.1 - 0.097 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 PRP79850.1 - 0.1 11.7 2.3 2.4 7.3 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit TsaE PF02367.17 PRP79850.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 PRP79850.1 - 0.13 11.7 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_18 PF13238.6 PRP79851.1 - 1.3e-22 80.7 0.3 2e-22 80.1 0.0 1.4 2 0 0 2 2 1 1 AAA domain dNK PF01712.19 PRP79851.1 - 4.4e-05 23.4 5.4 0.00087 19.2 2.0 2.2 1 1 0 2 2 2 1 Deoxynucleoside kinase NTPase_1 PF03266.15 PRP79851.1 - 0.00012 22.0 0.3 0.0004 20.3 0.0 1.8 2 0 0 2 2 2 1 NTPase Mg_chelatase PF01078.21 PRP79851.1 - 0.0004 19.8 0.0 0.0006 19.3 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PRP79851.1 - 0.00051 20.1 0.0 0.0012 18.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 PRP79851.1 - 0.00058 20.3 0.3 0.00077 19.9 0.3 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP79851.1 - 0.00066 20.1 0.0 0.0015 18.9 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 PRP79851.1 - 0.0011 19.2 0.5 0.21 11.7 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PRP79851.1 - 0.0015 18.8 0.8 0.0025 18.1 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PRP79851.1 - 0.0018 18.7 0.5 0.014 15.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain MCM PF00493.23 PRP79851.1 - 0.0019 17.3 0.0 0.0038 16.4 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain AAA_29 PF13555.6 PRP79851.1 - 0.0033 17.1 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 PRP79851.1 - 0.0046 16.7 0.2 0.017 14.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP79851.1 - 0.0059 17.0 0.1 0.018 15.4 0.0 1.9 2 1 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 PRP79851.1 - 0.006 16.9 0.6 0.018 15.3 0.1 1.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 PRP79851.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SKI PF01202.22 PRP79851.1 - 0.014 15.5 1.9 0.15 12.1 1.9 2.1 1 1 0 1 1 1 0 Shikimate kinase AsnA PF03590.15 PRP79851.1 - 0.022 14.5 0.5 0.073 12.8 0.0 1.8 2 0 0 2 2 2 0 Aspartate-ammonia ligase ATPase PF06745.13 PRP79851.1 - 0.036 13.4 0.1 0.036 13.4 0.1 1.7 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.27 PRP79851.1 - 0.037 14.6 4.2 0.32 11.5 4.2 2.1 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 PRP79851.1 - 0.043 13.5 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 PRP79851.1 - 0.047 13.0 0.9 0.062 12.6 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 PRP79851.1 - 0.049 12.7 0.6 0.092 11.8 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein CoaE PF01121.20 PRP79851.1 - 0.055 13.1 0.6 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Sigma54_activat PF00158.26 PRP79851.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 PRP79851.1 - 0.062 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 PRP79851.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 PRP79851.1 - 0.093 12.5 0.1 0.16 11.7 0.0 1.5 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 PRP79851.1 - 0.098 12.7 0.4 0.21 11.6 0.4 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 PRP79851.1 - 0.11 11.4 0.2 0.22 10.4 0.0 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 PRP79851.1 - 0.2 12.0 2.6 0.45 10.8 2.6 2.0 1 1 0 1 1 1 0 AAA domain GST_C_2 PF13410.6 PRP79852.1 - 5.8e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Polyketide_cyc2 PF10604.9 PRP79852.1 - 3.7e-07 30.5 0.0 7.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GST_C PF00043.25 PRP79852.1 - 1.5e-05 25.1 0.1 3.1e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP79852.1 - 0.00024 21.3 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP79852.1 - 0.0028 18.0 0.0 0.0064 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TPR_14 PF13428.6 PRP79853.1 - 8.5e-05 23.1 1.8 0.024 15.4 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP79853.1 - 0.011 15.9 1.0 2.7 8.3 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP79853.1 - 0.02 15.4 0.1 0.16 12.5 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RasGEF PF00617.19 PRP79853.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 RasGEF domain V-SNARE PF05008.15 PRP79853.1 - 0.057 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Rnk_N PF14760.6 PRP79853.1 - 0.1 13.1 1.2 0.34 11.4 0.0 2.5 2 0 0 2 2 2 0 Rnk N-terminus YfiO PF13525.6 PRP79853.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Outer membrane lipoprotein PseudoU_synth_1 PF01416.20 PRP79854.1 - 1.9e-25 89.4 0.0 5.4e-17 62.2 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase adh_short_C2 PF13561.6 PRP79855.1 - 4.7e-54 183.4 3.0 6e-54 183.1 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP79855.1 - 8.7e-47 159.1 2.0 1.1e-46 158.7 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP79855.1 - 6.6e-11 42.4 0.3 9.1e-11 42.0 0.3 1.1 1 0 0 1 1 1 1 KR domain PP2C PF00481.21 PRP79856.1 - 7.1e-54 183.1 0.0 8.9e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C LSM PF01423.22 PRP79857.1 - 2.9e-18 65.3 0.6 3.7e-18 65.0 0.6 1.1 1 0 0 1 1 1 1 LSM domain Suc_Fer-like PF06999.12 PRP79858.1 - 2.2e-34 119.1 0.0 2.5e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PPTA PF01239.22 PRP79859.1 - 6.4e-40 133.8 20.2 4.3e-11 42.2 0.9 5.7 5 1 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DDE_Tnp_ISL3 PF01610.17 PRP79859.1 - 0.31 10.7 8.6 0.2 11.3 2.4 2.3 2 1 0 2 2 2 0 Transposase NYD-SP28_assoc PF14775.6 PRP79860.1 - 1.1e-22 79.9 4.6 1.1e-22 79.9 4.6 4.3 4 1 0 4 4 4 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 PRP79860.1 - 2e-11 43.8 15.9 2e-11 43.8 15.9 6.2 4 2 3 8 8 8 1 Sperm tail zf-C2H2_aberr PF17017.5 PRP79860.1 - 0.033 14.3 0.8 0.033 14.3 0.8 3.8 2 1 0 3 3 3 0 Aberrant zinc-finger DUF1902 PF08972.11 PRP79860.1 - 0.18 11.8 1.3 1.2 9.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Lentiviral_Tat PF02998.14 PRP79860.1 - 2 8.5 4.9 0.88 9.7 0.6 2.6 2 0 0 2 2 2 0 Lentiviral Tat protein DUF3506 PF12014.8 PRP79863.1 - 7.1e-05 22.8 0.0 0.00065 19.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) GN3L_Grn1 PF08701.11 PRP79864.1 - 2.5e-20 72.3 21.0 2.5e-20 72.3 21.0 5.2 3 1 2 5 5 5 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 PRP79864.1 - 6e-16 58.5 8.0 4.8e-15 55.6 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP79864.1 - 1.1e-10 41.2 0.1 2.6e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP79864.1 - 4.9e-08 33.1 1.6 0.0077 16.2 0.4 3.1 1 1 1 2 2 2 2 RsgA GTPase Roc PF08477.13 PRP79864.1 - 0.044 14.0 0.2 4.8 7.4 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 PRP79864.1 - 0.086 13.2 0.0 0.086 13.2 0.0 3.5 3 2 0 3 3 3 0 AAA ATPase domain MeaB PF03308.16 PRP79864.1 - 0.11 11.4 0.0 0.11 11.4 0.0 2.6 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3761 PF12587.8 PRP79864.1 - 0.21 12.1 0.2 0.75 10.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) GTP_EFTU PF00009.27 PRP79864.1 - 0.45 10.0 12.3 0.07 12.7 0.2 4.2 3 2 0 3 3 3 0 Elongation factor Tu GTP binding domain BUD22 PF09073.10 PRP79864.1 - 3.7 6.8 58.7 0.063 12.6 39.5 2.4 2 0 0 2 2 2 0 BUD22 CH PF00307.31 PRP79866.1 - 3e-13 49.9 0.0 4.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.22 PRP79866.1 - 8.3e-12 45.1 5.7 1.5e-11 44.3 5.7 1.4 1 0 0 1 1 1 1 LIM domain CDC24 PF06395.11 PRP79866.1 - 0.0035 17.5 0.1 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 CDC24 Calponin Lentivirus_VIF PF05851.11 PRP79866.1 - 0.025 13.5 0.5 0.09 11.7 0.2 1.8 2 0 0 2 2 2 0 Lentivirus virion infectivity factor (VIF) zf_C2H2_13 PF18508.1 PRP79866.1 - 0.12 12.0 3.8 1.9 8.1 0.2 2.5 2 0 0 2 2 2 0 Zinc finger domain Sgf11 PF08209.11 PRP79866.1 - 0.25 11.0 5.9 8 6.1 3.1 2.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) A2L_zn_ribbon PF08792.10 PRP79866.1 - 0.71 9.7 6.0 38 4.1 0.0 3.2 2 1 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.10 PRP79866.1 - 4.5 7.5 8.8 22 5.3 4.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain PPR_2 PF13041.6 PRP79867.1 - 5.4e-15 55.3 1.0 0.00014 22.0 0.0 4.6 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.6 PRP79867.1 - 4.4e-14 52.3 2.4 0.0004 20.4 0.3 5.1 4 1 2 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP79867.1 - 2.9e-11 43.2 0.3 4.3e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 PRP79867.1 - 1.7e-05 24.1 1.8 0.99 8.5 0.2 4.3 2 2 1 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway PPR PF01535.20 PRP79867.1 - 0.027 14.7 9.2 17 5.9 0.0 6.3 7 1 0 7 7 7 0 PPR repeat PPR_1 PF12854.7 PRP79867.1 - 0.041 13.6 0.0 6.9 6.5 0.0 2.9 2 0 0 2 2 2 0 PPR repeat PIP49_N PF14875.6 PRP79867.1 - 0.082 12.8 0.2 9.1 6.1 0.1 2.5 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 Exog_C PF18026.1 PRP79867.1 - 0.15 12.2 0.8 8.5 6.5 0.1 3.1 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain VIT PF08487.10 PRP79868.1 - 5.1e-31 107.2 0.2 1.6e-30 105.6 0.2 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PRP79868.1 - 9.6e-23 80.8 0.0 2.9e-22 79.3 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP79868.1 - 6.3e-15 55.9 0.0 1.7e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 PRP79868.1 - 6.2e-10 38.8 0.1 1.6e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 PRP79868.1 - 3.5e-09 37.2 0.0 1.6e-08 35.2 0.0 2.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Sec34 PF04136.15 PRP79868.1 - 0.09 12.7 3.3 0.058 13.3 0.5 2.1 2 0 0 2 2 2 0 Sec34-like family DUF4259 PF14078.6 PRP79868.1 - 0.53 11.0 2.7 1.4 9.7 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) Actin PF00022.19 PRP79869.1 - 8.4e-58 195.9 1.2 3.1e-35 121.6 0.0 2.2 2 0 0 2 2 2 2 Actin Fungal_trans_2 PF11951.8 PRP79869.1 - 0.15 10.8 0.3 0.42 9.4 0.3 1.7 1 0 0 1 1 1 0 Fungal specific transcription factor domain TFIIF_beta_N PF17683.1 PRP79871.1 - 0.036 14.8 0.5 0.046 14.4 0.5 1.1 1 0 0 1 1 1 0 TFIIF, beta subunit N-terminus DUF3886 PF13025.6 PRP79871.1 - 2.7 8.2 13.9 4.8 7.4 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) MTS PF05175.14 PRP79872.1 - 0.00015 21.4 0.0 0.0015 18.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain UPF0020 PF01170.18 PRP79872.1 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 PRP79872.1 - 0.0096 16.6 0.0 0.016 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP79872.1 - 0.069 13.8 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Amidase PF01425.21 PRP79873.1 - 2.9e-77 260.5 0.0 3.7e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Pkinase_Tyr PF07714.17 PRP79874.1 - 1.9e-73 247.0 0.0 2.5e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79874.1 - 3.4e-49 167.6 0.0 4.9e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP79874.1 - 9.7e-27 92.6 102.6 4.2e-05 23.8 0.2 17.4 9 5 9 20 20 20 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP79874.1 - 8.7e-25 86.3 99.1 8.7e-08 31.8 2.3 16.5 12 3 8 20 20 20 14 Leucine rich repeat LRR_6 PF13516.6 PRP79874.1 - 3.1e-05 23.7 77.9 5 7.4 0.1 19.6 21 0 0 21 21 21 3 Leucine Rich repeat LRR_1 PF00560.33 PRP79874.1 - 0.00035 20.7 75.7 3.1 8.7 0.1 21.5 21 2 0 21 21 20 1 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP79874.1 - 0.00069 19.9 0.2 0.0018 18.6 0.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Kdo PF06293.14 PRP79874.1 - 0.0066 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM154 PF15102.6 PRP79874.1 - 0.01 15.8 1.4 0.022 14.7 1.4 1.5 1 0 0 1 1 1 0 TMEM154 protein family Pkinase_fungal PF17667.1 PRP79874.1 - 0.03 13.1 0.1 0.044 12.5 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase TFIID-31kDa PF02291.15 PRP79874.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Kinase-like PF14531.6 PRP79874.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Retrotrans_gag PF03732.17 PRP79876.1 - 0.023 15.0 0.1 0.077 13.3 0.1 1.9 1 0 0 1 1 1 0 Retrotransposon gag protein WD40 PF00400.32 PRP79879.1 - 9.1e-34 114.9 8.6 1.7e-06 28.6 0.6 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat LisH_TPL PF17814.1 PRP79879.1 - 4.5e-13 48.6 0.1 8.3e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain ANAPC4_WD40 PF12894.7 PRP79879.1 - 5.9e-12 45.7 0.5 7.3e-05 23.0 0.1 5.5 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP79879.1 - 1.3e-08 34.2 2.4 0.0089 15.0 0.3 3.9 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP79879.1 - 1.2e-07 30.7 3.9 0.0041 15.8 0.2 4.0 1 1 2 4 4 4 3 Nucleoporin Nup120/160 SdiA-regulated PF06977.11 PRP79879.1 - 0.016 14.4 0.0 0.042 13.1 0.0 1.6 2 0 0 2 2 2 0 SdiA-regulated PALB2_WD40 PF16756.5 PRP79879.1 - 0.036 13.0 0.8 0.32 9.9 0.1 2.3 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SNN_linker PF09050.10 PRP79879.1 - 0.22 11.3 2.1 0.47 10.3 2.1 1.6 1 0 0 1 1 1 0 Stannin unstructured linker DnaJ PF00226.31 PRP79880.1 - 1.8e-24 85.6 0.8 3.5e-24 84.7 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain LRR_8 PF13855.6 PRP79880.1 - 2.6e-22 78.4 18.0 1.6e-11 43.8 1.8 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PRP79880.1 - 1.3e-19 69.9 12.0 5.3e-07 29.9 0.7 4.1 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP79880.1 - 4.5e-07 29.5 3.9 0.00019 21.0 0.5 2.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 PRP79880.1 - 4.9e-07 29.4 7.9 1.2 10.0 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP79880.1 - 0.0047 16.9 15.2 3.7 7.9 0.1 6.4 7 0 0 7 7 7 1 Leucine Rich repeat RsmF_methylt_CI PF17126.5 PRP79880.1 - 0.035 14.1 0.2 4.5 7.4 0.0 3.0 2 1 1 3 3 3 0 RsmF rRNA methyltransferase first C-terminal domain IBN_N PF03810.19 PRP79881.1 - 3.4e-05 23.7 0.2 9.1e-05 22.3 0.2 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Pkinase_Tyr PF07714.17 PRP79882.1 - 3.5e-14 52.7 0.2 3.4e-08 33.1 0.0 2.9 1 1 1 2 2 2 2 Protein tyrosine kinase zf-C3HC4_2 PF13923.6 PRP79882.1 - 3.1e-11 42.9 10.6 3.1e-11 42.9 10.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LRR_8 PF13855.6 PRP79882.1 - 7.1e-11 41.7 1.7 1.9e-10 40.3 1.7 1.8 1 0 0 1 1 1 1 Leucine rich repeat GPS PF01825.21 PRP79882.1 - 7.4e-10 39.2 2.3 2.4e-09 37.6 2.3 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP79882.1 - 3.4e-07 29.9 0.1 0.016 14.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain RNF220 PF15926.5 PRP79882.1 - 1.4e-06 28.1 5.9 1.4e-06 28.1 5.9 2.1 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-RING_5 PF14634.6 PRP79882.1 - 0.00013 21.9 8.1 0.00032 20.6 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PRP79882.1 - 0.00021 21.1 9.8 0.00021 21.1 9.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP79882.1 - 0.00067 19.5 9.1 0.0018 18.1 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.7 PRP79882.1 - 0.0017 18.8 8.8 0.033 14.6 2.2 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP79882.1 - 0.0029 17.9 1.3 2.9 8.8 0.0 3.7 3 0 0 3 3 2 1 Leucine Rich Repeat Mid2 PF04478.12 PRP79882.1 - 0.0086 15.9 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor zf-RING_UBOX PF13445.6 PRP79882.1 - 0.012 15.6 6.1 0.035 14.1 6.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 PRP79882.1 - 0.012 15.9 11.4 0.031 14.6 11.4 1.8 1 0 0 1 1 1 0 Ring finger domain SCAB_CC PF16712.5 PRP79882.1 - 0.063 13.1 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Prok-RING_4 PF14447.6 PRP79882.1 - 0.41 10.6 9.2 1.1 9.2 9.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PRP79882.1 - 0.59 10.3 6.8 1.8 8.7 6.8 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 PRP79882.1 - 1.6 8.6 6.2 0.71 9.7 3.4 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit LRR_6 PF13516.6 PRP79882.1 - 2.5 8.4 6.5 1.9 8.7 0.3 3.6 3 0 0 3 3 3 0 Leucine Rich repeat zf-rbx1 PF12678.7 PRP79882.1 - 2.7 8.4 8.0 9 6.7 8.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PRP79882.1 - 7.7 6.8 10.1 19 5.5 10.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase_Tyr PF07714.17 PRP79883.1 - 1.5e-29 103.0 1.4 2.5e-29 102.4 1.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79883.1 - 2.3e-19 69.8 0.6 4.5e-19 68.9 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP79883.1 - 1.1e-17 63.8 34.4 0.00036 20.9 0.5 6.2 5 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP79883.1 - 3.4e-13 49.2 34.8 1.7e-05 24.5 2.4 5.9 2 2 3 5 5 5 5 Leucine rich repeat GPS PF01825.21 PRP79883.1 - 1.7e-09 38.1 2.3 4.5e-09 36.7 2.3 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRRNT_2 PF08263.12 PRP79883.1 - 0.02 15.2 4.6 0.048 14.0 4.6 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Dsl1_N PF11988.8 PRP79883.1 - 0.064 12.2 6.6 0.39 9.6 5.6 2.1 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal DUF2448 PF10476.9 PRP79883.1 - 0.19 11.6 1.1 0.4 10.5 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) LRR_8 PF13855.6 PRP79884.1 - 9.4e-11 41.3 36.8 6.3e-08 32.3 7.5 4.7 2 2 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 PRP79884.1 - 7.6e-09 35.7 38.6 0.0015 18.9 3.2 5.1 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP79884.1 - 7.7e-09 35.9 2.7 2.5e-08 34.3 2.7 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP79884.1 - 6.2e-08 32.2 0.0 4.8e-07 29.3 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79884.1 - 0.021 14.2 0.0 0.068 12.5 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain SKI PF01202.22 PRP79885.1 - 2e-26 93.0 0.0 3.6e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Thr_synth_N PF14821.6 PRP79885.1 - 1.3e-10 41.3 0.0 5.4e-10 39.3 0.0 2.1 1 1 0 1 1 1 1 Threonine synthase N terminus AAA_18 PF13238.6 PRP79885.1 - 3.9e-07 30.7 0.0 1.2e-06 29.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain PALP PF00291.25 PRP79885.1 - 9.8e-07 28.5 0.0 7e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_17 PF13207.6 PRP79885.1 - 5.4e-05 23.6 0.8 0.001 19.5 0.2 2.7 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 PRP79885.1 - 8.7e-05 22.7 0.0 0.00036 20.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 PRP79885.1 - 0.00089 19.7 0.0 0.0029 18.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PRP79885.1 - 0.0031 17.3 0.0 0.015 15.1 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 PRP79885.1 - 0.0032 17.4 0.0 0.0086 16.0 0.0 1.7 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 PRP79885.1 - 0.0039 17.6 0.0 0.012 16.1 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 PRP79885.1 - 0.005 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 PRP79885.1 - 0.0078 16.3 0.1 0.22 11.6 0.0 2.8 3 0 0 3 3 3 1 Adenylate kinase dNK PF01712.19 PRP79885.1 - 0.0079 16.1 0.1 2.1 8.2 0.1 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_5 PF07728.14 PRP79885.1 - 0.011 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 PRP79885.1 - 0.016 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_32 PF13654.6 PRP79885.1 - 0.02 13.7 0.1 0.12 11.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 PRP79885.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Mg_chelatase PF01078.21 PRP79885.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 PRP79885.1 - 0.027 15.0 0.0 0.056 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 PRP79885.1 - 0.035 13.8 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PRP79885.1 - 0.047 14.0 0.0 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PRP79885.1 - 0.052 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TniB PF05621.11 PRP79885.1 - 0.054 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 PRP79885.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 PRP79885.1 - 0.072 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 PRP79885.1 - 0.073 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 PRP79885.1 - 0.09 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain PH PF00169.29 PRP79886.1 - 2e-06 28.2 0.6 3.3e-06 27.5 0.6 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 PRP79886.1 - 0.00076 19.8 0.1 0.0016 18.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PRP79886.1 - 0.033 14.6 0.1 0.09 13.2 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Lyase_1 PF00206.20 PRP79887.1 - 6.5e-118 393.7 0.0 1e-117 393.0 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 PRP79887.1 - 3.5e-20 72.2 0.3 1.2e-19 70.5 0.1 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus DUF4288 PF14119.6 PRP79887.1 - 0.1 13.0 0.1 0.23 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) TFIIB_C_1 PF18542.1 PRP79887.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 adh_short PF00106.25 PRP79888.1 - 1.6e-23 83.2 0.0 2.4e-22 79.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP79888.1 - 2.1e-14 53.7 0.0 1.3e-13 51.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP79888.1 - 9.5e-12 45.2 0.1 1.5e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP79888.1 - 0.00038 20.0 0.0 0.00059 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.9 PRP79888.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain ABC_sub_bind PF04392.12 PRP79888.1 - 0.017 14.4 0.3 0.026 13.8 0.3 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein Peripla_BP_6 PF13458.6 PRP79888.1 - 0.024 14.3 0.1 0.038 13.7 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein GDP_Man_Dehyd PF16363.5 PRP79888.1 - 0.042 13.2 0.6 0.4 10.0 0.6 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PRP79888.1 - 0.084 12.0 0.4 0.14 11.2 0.4 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 PRP79888.1 - 0.13 12.4 0.2 0.23 11.5 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Jag_N PF14804.6 PRP79888.1 - 0.26 11.7 2.2 22 5.5 0.1 2.7 3 0 0 3 3 3 0 Jag N-terminus Sina PF03145.16 PRP79889.1 - 0.021 14.8 3.4 0.021 14.8 3.4 2.1 2 1 0 2 2 2 0 Seven in absentia protein family VWA_CoxE PF05762.14 PRP79891.1 - 0.008 15.6 0.1 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Cyclin_N PF00134.23 PRP79894.1 - 1e-42 144.9 1.2 1.9e-42 144.0 1.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP79894.1 - 4.5e-37 126.8 0.5 1.5e-36 125.1 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Glutaredoxin2_C PF04399.13 PRP79897.1 - 1.4 8.7 5.3 19 5.1 0.5 3.2 2 1 0 3 3 3 0 Glutaredoxin 2, C terminal domain TMEM189_B_dmain PF10520.9 PRP79898.1 - 4.1e-65 219.1 2.0 4.1e-65 219.1 2.0 1.4 2 0 0 2 2 2 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 PRP79898.1 - 0.0039 17.5 5.7 0.0039 17.5 5.7 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily MFS_3 PF05977.13 PRP79898.1 - 0.056 11.8 2.8 0.24 9.7 0.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector MIP PF00230.20 PRP79899.1 - 4.5e-63 213.0 17.3 6.9e-63 212.4 17.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein RabGAP-TBC PF00566.18 PRP79899.1 - 3.3e-24 85.7 1.1 7e-24 84.7 1.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 PRP79899.1 - 2.4e-07 30.5 0.3 7.1e-07 29.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP79899.1 - 2.9e-05 23.8 0.4 0.00013 21.7 0.1 2.3 2 0 0 2 2 2 1 F-box domain SMI1_KNR4 PF09346.10 PRP79899.1 - 0.0063 16.9 1.8 0.013 15.9 0.5 2.1 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) HAP PF03866.13 PRP79899.1 - 0.037 14.0 2.4 0.082 12.9 2.4 1.5 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) PI3K_1B_p101 PF10486.9 PRP79899.1 - 0.062 11.1 4.0 0.095 10.5 4.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Fanconi_A PF03511.14 PRP79899.1 - 0.18 11.7 0.6 7.8 6.5 0.2 3.3 4 0 0 4 4 4 0 Fanconi anaemia group A protein CENP-B_dimeris PF09026.10 PRP79899.1 - 0.33 11.3 11.0 0.19 12.2 8.0 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4820 PF16091.5 PRP79899.1 - 0.79 9.0 3.3 2.1 7.7 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TRAP_alpha PF03896.16 PRP79899.1 - 1.1 8.4 6.0 2.3 7.4 6.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 PRP79899.1 - 2.1 6.3 18.6 3.7 5.5 18.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2721 PF11026.8 PRP79899.1 - 3.3 7.6 4.6 20 5.0 2.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) RPA43_OB PF17875.1 PRP79899.1 - 8 7.1 6.7 4.9 7.8 1.1 2.8 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I GGACT PF06094.12 PRP79900.1 - 7.7e-09 36.2 0.0 1.8e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 PRP79900.1 - 0.00021 21.6 0.0 0.00058 20.2 0.0 1.7 1 1 0 1 1 1 1 AIG2-like family SNF2_N PF00176.23 PRP79901.1 - 2.9e-45 154.5 0.8 4.7e-45 153.8 0.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP79901.1 - 1.1e-16 61.2 0.0 2.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP79901.1 - 1.2e-08 35.1 0.0 5.8e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 PRP79901.1 - 0.011 15.4 0.4 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 PRP79901.1 - 0.047 12.9 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CLLAC PF15675.5 PRP79902.1 - 5.2 6.7 11.9 0.35 10.4 1.8 2.6 2 0 0 2 2 2 0 CLLAC-motif containing domain Peptidase_S9_N PF02897.15 PRP79903.1 - 4.2e-105 351.9 9.0 6.7e-105 351.3 9.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PRP79903.1 - 9.1e-60 201.7 0.0 1.5e-59 201.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family 2OG-FeII_Oxy_2 PF13532.6 PRP79903.1 - 2.3e-16 60.6 0.1 5.1e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 PRP79903.1 - 6.4e-14 52.4 0.1 2.2e-13 50.6 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP79903.1 - 7.6e-12 45.8 0.1 2.6e-11 44.1 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP79903.1 - 8.9e-08 32.1 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP79903.1 - 5.8e-06 26.2 0.0 1.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP79903.1 - 2.9e-05 24.7 0.0 0.00019 22.1 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 PRP79903.1 - 0.0002 21.1 0.0 0.00066 19.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ubie_methyltran PF01209.18 PRP79903.1 - 0.00069 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 PRP79903.1 - 0.0062 15.1 0.0 0.012 14.2 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase GFO_IDH_MocA PF01408.22 PRP79904.1 - 1.7e-23 83.7 0.1 2.7e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 PRP79904.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 PRP79904.1 - 0.0065 17.0 0.0 0.057 14.0 0.0 2.2 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NBD94 PF16830.5 PRP79904.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH F-box PF00646.33 PRP79905.1 - 0.0017 18.2 0.1 0.0052 16.6 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP79905.1 - 0.0075 16.1 0.7 0.032 14.1 0.1 2.4 2 0 0 2 2 2 1 F-box-like DUF1231 PF06802.11 PRP79905.1 - 0.045 12.9 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) PTPlike_phytase PF14566.6 PRP79906.1 - 2.1e-41 141.7 0.4 6.1e-41 140.1 0.0 2.0 3 0 0 3 3 3 1 Inositol hexakisphosphate DSPc PF00782.20 PRP79906.1 - 0.013 15.3 0.0 0.045 13.6 0.0 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PEPcase PF00311.17 PRP79909.1 - 0.0063 14.7 0.0 0.0082 14.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Gemin6 PF06372.12 PRP79909.1 - 0.042 13.4 0.0 0.051 13.1 0.0 1.1 1 0 0 1 1 1 0 Gemin6 protein PTPlike_phytase PF14566.6 PRP79910.1 - 2e-41 141.7 0.4 5.9e-41 140.2 0.0 2.0 3 0 0 3 3 3 1 Inositol hexakisphosphate DSPc PF00782.20 PRP79910.1 - 0.012 15.4 0.0 0.043 13.6 0.0 1.9 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain F-box PF00646.33 PRP79911.1 - 0.0018 18.1 0.1 0.006 16.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP79911.1 - 0.0033 17.3 1.7 0.038 13.9 0.1 3.2 3 0 0 3 3 3 1 F-box-like GFO_IDH_MocA PF01408.22 PRP79912.1 - 1.7e-23 83.7 0.1 2.7e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 PRP79912.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 PRP79912.1 - 0.0065 17.0 0.0 0.057 14.0 0.0 2.2 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NBD94 PF16830.5 PRP79912.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Peptidase_S9_N PF02897.15 PRP79913.1 - 4.1e-105 352.0 9.0 6.4e-105 351.3 9.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PRP79913.1 - 8.7e-60 201.8 0.0 1.4e-59 201.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family 2OG-FeII_Oxy_2 PF13532.6 PRP79913.1 - 2.1e-16 60.7 1.1 4.9e-16 59.5 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 PRP79913.1 - 6.3e-14 52.4 0.1 2.2e-13 50.7 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP79913.1 - 7.3e-12 45.8 0.1 2.5e-11 44.1 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP79913.1 - 9.1e-08 32.0 0.0 2.4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP79913.1 - 1.3e-05 25.1 0.0 3.8e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP79913.1 - 2.7e-05 24.8 0.0 0.00018 22.2 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 PRP79913.1 - 0.0002 21.1 0.0 0.00064 19.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ubie_methyltran PF01209.18 PRP79913.1 - 0.00074 18.9 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 PRP79913.1 - 0.0071 14.9 0.0 0.014 14.0 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CLLAC PF15675.5 PRP79914.1 - 1.5 8.4 11.9 0.2 11.2 1.8 2.8 2 0 0 2 2 2 0 CLLAC-motif containing domain SNF2_N PF00176.23 PRP79916.1 - 2.8e-45 154.6 0.7 4.2e-45 154.0 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP79916.1 - 1.2e-16 61.1 0.0 2.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP79916.1 - 3.9e-08 33.5 0.0 1.7e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 PRP79916.1 - 0.014 15.0 0.8 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 PRP79916.1 - 0.05 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GGACT PF06094.12 PRP79917.1 - 8.5e-09 36.1 0.0 1.7e-08 35.1 0.0 1.6 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 PRP79917.1 - 0.003 17.9 0.0 0.0079 16.6 0.0 1.7 1 1 0 1 1 1 1 AIG2-like family MIP PF00230.20 PRP79918.1 - 4.5e-63 213.0 17.3 7.2e-63 212.3 17.3 1.3 1 0 0 1 1 1 1 Major intrinsic protein RabGAP-TBC PF00566.18 PRP79918.1 - 3.4e-24 85.7 1.1 7.2e-24 84.6 1.1 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.7 PRP79918.1 - 2.5e-07 30.5 0.3 7.3e-07 29.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP79918.1 - 3.1e-05 23.7 0.4 0.00014 21.7 0.1 2.3 2 0 0 2 2 2 1 F-box domain SMI1_KNR4 PF09346.10 PRP79918.1 - 0.0079 16.6 1.0 0.022 15.1 0.2 2.1 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) TEX19 PF15553.6 PRP79918.1 - 0.028 14.4 2.8 0.035 14.1 0.6 2.2 3 0 0 3 3 3 0 Testis-expressed protein 19 HAP PF03866.13 PRP79918.1 - 0.037 14.0 2.4 0.084 12.9 2.4 1.5 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) PI3K_1B_p101 PF10486.9 PRP79918.1 - 0.44 8.3 1.6 0.7 7.6 1.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RPA43_OB PF17875.1 PRP79918.1 - 0.94 10.1 3.6 2.7 8.6 0.2 2.7 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I FAM176 PF14851.6 PRP79918.1 - 2.5 7.8 7.9 7.9 6.1 7.9 1.8 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 PRP79918.1 - 3.5 5.6 15.3 6.3 4.8 15.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 PRP79918.1 - 4.9 5.3 10.2 8.1 4.5 10.2 1.2 1 0 0 1 1 1 0 Nop14-like family TMEM189_B_dmain PF10520.9 PRP79919.1 - 1.3e-65 220.8 2.0 2e-65 220.1 2.0 1.3 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 PRP79919.1 - 0.0017 18.7 5.5 0.0017 18.7 5.5 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Sec1 PF00995.23 PRP79920.1 - 2.8e-120 403.3 0.4 3.3e-120 403.0 0.4 1.0 1 0 0 1 1 1 1 Sec1 family G-gamma PF00631.22 PRP79921.1 - 2.8e-14 52.9 0.1 3.2e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 GGL domain TALPID3 PF15324.6 PRP79921.1 - 0.044 11.5 0.3 0.038 11.7 0.3 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF3573 PF12097.8 PRP79921.1 - 0.11 11.3 0.1 0.12 11.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Metallophos PF00149.28 PRP79923.1 - 1.1e-13 52.2 0.1 1.9e-13 51.4 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PRP79923.1 - 0.028 14.6 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Fapy_DNA_glyco PF01149.24 PRP79924.1 - 3e-26 92.3 0.0 5.2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 PRP79924.1 - 1.2e-19 70.1 0.0 1.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain CDC45 PF02724.14 PRP79924.1 - 0.89 7.8 4.2 1.1 7.4 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 PRP79924.1 - 2.3 7.9 4.8 3.8 7.2 4.8 1.3 1 0 0 1 1 1 0 FAM176 family UPF0239 PF06783.11 PRP79924.1 - 3 8.1 5.5 6 7.1 5.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Tetraspanin PF00335.20 PRP79925.1 - 0.00021 21.1 13.8 0.00065 19.5 13.8 1.6 1 1 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 PRP79925.1 - 0.0013 18.8 12.0 0.0027 17.8 11.0 1.9 1 1 0 1 1 1 1 CD20-like family DUF4383 PF14325.6 PRP79925.1 - 0.58 10.4 5.2 5.3 7.3 5.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) 2TM PF13239.6 PRP79925.1 - 0.92 9.9 7.7 0.068 13.5 1.3 2.1 2 0 0 2 2 2 0 2TM domain DUF4282 PF14110.6 PRP79925.1 - 1.5 9.6 10.5 0.23 12.2 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) SGP PF17228.2 PRP79925.1 - 5.9 7.8 20.6 26 5.8 20.6 2.0 1 1 0 1 1 1 0 Sulphur globule protein Laminin_G_3 PF13385.6 PRP79926.1 - 2e-16 60.5 0.7 3.7e-16 59.6 0.7 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Methyltransf_16 PF10294.9 PRP79926.1 - 6.9e-10 38.9 0.2 3.4e-08 33.4 0.0 2.2 1 1 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 PRP79926.1 - 1e-05 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP79926.1 - 0.0091 16.7 0.0 0.038 14.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP79926.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP79926.1 - 0.03 15.0 0.0 0.15 12.8 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 PRP79926.1 - 0.086 13.5 0.1 1.7 9.3 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 PRP79926.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Hep_core_N PF08290.11 PRP79928.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger ACOX PF01756.19 PRP79929.1 - 4.9e-42 143.5 0.1 8.9e-42 142.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PRP79929.1 - 5.9e-10 39.2 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 PRP79929.1 - 0.00061 20.0 0.1 0.0043 17.3 0.1 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase_Tyr PF07714.17 PRP79930.1 - 2.7e-60 203.8 0.8 1.5e-59 201.4 0.8 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP79930.1 - 2.3e-42 145.2 0.1 8.7e-42 143.3 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 PRP79930.1 - 0.0061 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Insulin_TMD PF17870.1 PRP79930.1 - 0.01 15.9 0.2 0.025 14.7 0.2 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Kinase-like PF14531.6 PRP79930.1 - 0.018 14.3 0.1 0.046 13.0 0.1 1.5 1 1 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 PRP79930.1 - 0.029 13.3 0.1 0.065 12.2 0.1 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DUF3952 PF13130.6 PRP79930.1 - 0.038 14.2 0.9 0.24 11.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) EphA2_TM PF14575.6 PRP79930.1 - 0.092 13.6 0.1 0.25 12.3 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain APH PF01636.23 PRP79930.1 - 0.22 11.4 0.0 0.59 10.0 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family CBS PF00571.28 PRP79931.1 - 0.13 12.7 0.1 2.6 8.6 0.0 2.4 2 0 0 2 2 2 0 CBS domain Pkinase PF00069.25 PRP79933.1 - 3.2e-48 164.4 0.0 7.4e-48 163.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain RCC1 PF00415.18 PRP79933.1 - 8.7e-42 141.5 20.4 4.8e-13 49.5 0.0 8.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 PRP79933.1 - 3.1e-41 141.4 0.0 5.7e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.6 PRP79933.1 - 1.1e-28 98.4 36.9 1.4e-06 27.9 2.5 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat SAM_1 PF00536.30 PRP79933.1 - 0.00055 20.3 0.2 0.0019 18.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 PRP79933.1 - 0.00064 18.6 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ASH PF15780.5 PRP79933.1 - 0.057 13.6 0.3 0.18 12.0 0.3 1.8 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF3455 PF11937.8 PRP79933.1 - 0.088 13.2 0.1 0.27 11.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3455) PapD_N PF00345.20 PRP79933.1 - 0.094 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain SAM_2 PF07647.17 PRP79933.1 - 0.12 12.4 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) fn3_6 PF17766.1 PRP79933.1 - 0.16 12.2 1.0 0.38 11.0 1.0 1.6 1 0 0 1 1 1 0 Fibronectin type-III domain Pkinase PF00069.25 PRP79934.1 - 8.4e-72 241.7 0.0 9.6e-72 241.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79934.1 - 2.8e-32 112.0 0.0 3.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP79934.1 - 2.7e-09 36.5 0.0 3.7e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP79934.1 - 0.00056 19.3 0.0 0.0009 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP79934.1 - 0.00094 19.2 0.1 0.007 16.3 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP79934.1 - 0.0022 17.4 0.4 0.53 9.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 PRP79934.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 PRP79934.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 1 0 1 1 1 0 RIO1 family DUF2987 PF11205.8 PRP79934.1 - 0.14 12.1 0.1 0.31 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) RasGAP PF00616.19 PRP79935.1 - 8.6e-23 81.1 0.8 1.8e-21 76.8 0.8 2.3 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase PSI PF01437.25 PRP79935.1 - 6.4e-09 36.2 48.8 0.0019 18.7 3.0 5.2 5 0 0 5 5 5 4 Plexin repeat EphA2_TM PF14575.6 PRP79935.1 - 0.007 17.2 0.0 0.02 15.7 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 PRP79935.1 - 0.012 15.3 3.2 0.024 14.4 3.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM154 PF15102.6 PRP79935.1 - 0.02 14.8 1.5 0.062 13.2 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family Mid2 PF04478.12 PRP79935.1 - 0.026 14.4 0.5 0.075 12.9 0.5 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Collectrin PF16959.5 PRP79935.1 - 0.079 12.7 1.6 0.18 11.6 1.6 1.5 1 0 0 1 1 1 0 Renal amino acid transporter SKG6 PF08693.10 PRP79935.1 - 0.1 12.0 9.9 0.23 10.9 9.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Orf78 PF06024.12 PRP79935.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF3827 PF12877.7 PRP79935.1 - 0.56 8.5 6.5 0.031 12.7 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) Saf_2TM PF18303.1 PRP79936.1 - 0.024 14.2 3.4 3 7.4 1.7 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF3792 PF12670.7 PRP79936.1 - 0.96 9.6 9.0 6.5 7.0 9.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) Pkinase_Tyr PF07714.17 PRP79937.1 - 1.6e-91 306.2 0.0 6.8e-77 258.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP79937.1 - 1.5e-66 224.5 0.0 1.2e-46 159.3 0.0 2.8 2 0 0 2 2 2 2 Protein kinase domain AAA_16 PF13191.6 PRP79937.1 - 1.9e-38 132.5 0.0 4.1e-38 131.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain HATPase_c PF02518.26 PRP79937.1 - 1.1e-24 87.1 0.2 5e-24 85.0 0.2 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP79937.1 - 2.1e-21 76.2 0.3 2e-20 73.1 0.2 2.8 2 0 0 2 2 2 1 Response regulator receiver domain GAF PF01590.26 PRP79937.1 - 4.5e-13 50.0 0.0 1.3e-12 48.5 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 PRP79937.1 - 1.3e-08 35.2 0.0 3.7e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 PRP79937.1 - 1.4e-08 34.7 0.2 5.7e-08 32.7 0.2 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Kinase-like PF14531.6 PRP79937.1 - 1.1e-06 28.2 0.0 0.007 15.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like HATPase_c_3 PF13589.6 PRP79937.1 - 0.0002 21.2 0.0 0.00054 19.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Haspin_kinase PF12330.8 PRP79937.1 - 0.00073 18.6 0.4 0.035 13.0 0.1 2.9 2 1 0 2 2 2 1 Haspin like kinase domain RsgA_GTPase PF03193.16 PRP79937.1 - 0.011 15.7 0.3 0.056 13.4 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase GAF_3 PF13492.6 PRP79937.1 - 0.026 14.9 0.0 0.059 13.7 0.0 1.7 1 0 0 1 1 1 0 GAF domain AAA_22 PF13401.6 PRP79937.1 - 0.036 14.3 0.2 0.47 10.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Nab2 PF11517.8 PRP79937.1 - 0.092 13.1 0.2 0.36 11.1 0.2 2.0 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Insulin_TMD PF17870.1 PRP79937.1 - 0.21 11.7 2.5 0.61 10.2 2.5 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Chlam_PMP PF02415.17 PRP79937.1 - 2.9 8.5 29.5 0.051 14.1 0.2 7.8 10 0 0 10 10 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TPR_12 PF13424.6 PRP79937.1 - 8.4 6.8 9.4 2.1 8.7 4.4 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.12 PRP79938.1 - 7.1e-09 35.0 0.3 2.2e-07 30.1 0.1 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 90 RasGEF PF00617.19 PRP79939.1 - 1.8e-47 161.9 2.4 1.8e-47 161.9 2.4 2.1 2 0 0 2 2 2 1 RasGEF domain RhoGAP PF00620.27 PRP79939.1 - 4.1e-11 42.9 0.3 1.6e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.20 PRP79939.1 - 1.1e-05 25.6 0.0 8.1e-05 22.8 0.0 2.6 1 0 0 1 1 1 1 RasGEF N-terminal motif CAP PF00188.26 PRP79940.1 - 0.0056 17.5 0.6 0.011 16.6 0.6 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family VirB8 PF04335.13 PRP79940.1 - 0.0076 16.1 2.4 0.038 13.8 0.1 2.1 1 1 1 2 2 2 1 VirB8 protein T3SS_ExsE PF18286.1 PRP79940.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Type III secretion system ExsE DUF676 PF05057.14 PRP79941.1 - 1.1e-40 139.5 0.0 2.1e-40 138.6 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 PRP79941.1 - 1.3e-07 31.6 0.1 4.9e-06 26.4 0.1 2.5 1 1 0 1 1 1 1 PGAP1-like protein DUF3657 PF12394.8 PRP79941.1 - 1.4e-07 31.9 0.0 1e-06 29.2 0.0 2.4 2 0 0 2 2 2 1 Protein FAM135 Palm_thioest PF02089.15 PRP79941.1 - 8.7e-06 25.8 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LCAT PF02450.15 PRP79941.1 - 0.00076 18.8 0.1 0.0024 17.1 0.0 1.8 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 PRP79941.1 - 0.0033 16.8 0.3 0.01 15.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 PRP79941.1 - 0.0041 16.8 0.4 0.059 13.0 0.1 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Enolase_N PF03952.16 PRP79941.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Enolase, N-terminal domain HMA PF00403.26 PRP79942.1 - 5.4e-17 62.0 0.5 1.2e-16 60.9 0.5 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Cupin_2 PF07883.11 PRP79942.1 - 5.7e-08 32.4 1.3 2e-07 30.6 1.1 1.8 2 0 0 2 2 2 1 Cupin domain Fer2_BFD PF04324.15 PRP79942.1 - 0.09 13.1 0.7 0.57 10.6 0.1 2.3 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF4246 PF14033.6 PRP79943.1 - 1.2e-133 446.6 0.0 1.8e-133 446.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arf PF00025.21 PRP79943.1 - 6.3e-60 201.6 0.2 1.2e-59 200.7 0.2 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PRP79943.1 - 1.4e-11 44.7 0.0 3.8e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PRP79943.1 - 2.3e-11 43.5 0.0 3.8e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 PRP79943.1 - 2.6e-11 43.4 0.0 4.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PRP79943.1 - 1.7e-09 37.4 0.0 3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PRP79943.1 - 2.1e-05 24.6 0.0 4.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PRP79943.1 - 0.00046 19.4 0.2 0.21 10.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit 2OG-FeII_Oxy_5 PF13759.6 PRP79943.1 - 0.05 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Nab2p_Zf1 PF18260.1 PRP79943.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 DHR-2 PF06920.13 PRP79944.1 - 3.7e-110 369.1 2.3 6.3e-110 368.3 2.3 1.2 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 PRP79944.1 - 5.5e-23 81.8 2.6 8.8e-23 81.1 1.1 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 PRP79944.1 - 0.00016 22.1 0.0 0.00067 20.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) Vac14_Fab1_bd PF12755.7 PRP79944.1 - 0.014 16.0 0.0 0.061 13.9 0.0 2.1 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region DOCK_N PF16172.5 PRP79944.1 - 0.029 13.3 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 DOCK N-terminus AAA_31 PF13614.6 PRP79945.1 - 0.016 15.2 0.1 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain PAR1 PF06521.11 PRP79945.1 - 0.034 13.8 0.1 0.089 12.4 0.1 1.7 1 0 0 1 1 1 0 PAR1 protein CSN8_PSD8_EIF3K PF10075.9 PRP79947.1 - 3.4e-29 101.7 0.5 2.5e-28 98.9 0.1 2.3 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family FERM_M PF00373.18 PRP79947.1 - 8.6e-26 90.7 0.0 2.2e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 FERM central domain RA PF00788.23 PRP79947.1 - 0.00028 21.5 0.0 0.00072 20.1 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAC3_GANP PF03399.16 PRP79947.1 - 0.0003 20.3 0.5 0.00047 19.6 0.5 1.3 1 0 0 1 1 1 1 SAC3/GANP family IRS PF02174.17 PRP79947.1 - 0.0053 16.6 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 PTB domain (IRS-1 type) UPF0172 PF03665.13 PRP79948.1 - 1.2e-23 84.2 0.0 1.6e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Aldo_ket_red PF00248.21 PRP79949.1 - 3.6e-51 174.1 0.0 4.1e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TRAM_LAG1_CLN8 PF03798.16 PRP79950.1 - 7.1e-09 35.7 17.6 7.1e-09 35.7 17.6 1.6 2 0 0 2 2 2 1 TLC domain TctB PF07331.11 PRP79950.1 - 0.058 13.7 0.2 0.058 13.7 0.2 2.2 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF1772 PF08592.11 PRP79950.1 - 0.065 13.5 0.7 0.065 13.5 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) WD40 PF00400.32 PRP79951.1 - 5.7e-19 68.1 7.9 4.3e-05 24.2 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP79951.1 - 6.8e-15 55.1 0.6 0.044 14.1 0.0 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP79951.1 - 0.0011 18.0 0.1 9.1 5.1 0.0 3.6 2 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP79951.1 - 0.0025 17.7 0.0 0.51 10.2 0.0 3.1 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 PRP79951.1 - 0.0069 16.0 0.0 0.25 10.9 0.0 2.6 1 1 1 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.16 PRP79951.1 - 0.08 11.5 0.0 0.4 9.2 0.0 2.0 2 1 0 2 2 2 0 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 PRP79951.1 - 0.086 11.9 0.0 7.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region Glyoxal_oxid_N PF07250.11 PRP79951.1 - 0.09 12.0 0.5 0.19 10.9 0.5 1.6 1 1 0 1 1 1 0 Glyoxal oxidase N-terminus SUKH_6 PF14568.6 PRP79951.1 - 0.097 13.1 0.4 0.95 9.9 0.0 2.7 2 2 0 2 2 2 0 SMI1-KNR4 cell-wall PBECR2 PF18810.1 PRP79951.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease2 WD40 PF00400.32 PRP79952.1 - 5.3e-48 160.0 36.7 8.1e-09 36.0 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP79952.1 - 9.3e-17 61.1 5.9 0.026 14.8 0.0 6.2 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 PRP79952.1 - 5e-05 21.5 5.7 0.0002 19.6 1.4 2.5 1 1 3 4 4 4 3 IKI3 family eIF2A PF08662.11 PRP79952.1 - 0.00011 22.1 0.5 0.0054 16.6 0.0 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 PRP79952.1 - 0.00074 18.7 0.4 0.037 13.1 0.3 2.7 1 1 1 2 2 2 1 Coatomer WD associated region Lactonase PF10282.9 PRP79952.1 - 0.057 12.7 0.0 0.46 9.7 0.0 2.2 1 1 2 3 3 3 0 Lactonase, 7-bladed beta-propeller DUF4082 PF13313.6 PRP79952.1 - 0.072 13.1 1.2 0.48 10.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4082) DUF2387 PF09526.10 PRP79952.1 - 0.18 12.0 7.2 14 5.9 0.1 3.7 4 0 0 4 4 4 0 Probable metal-binding protein (DUF2387) GDPD PF03009.17 PRP79953.1 - 5.4e-24 85.3 0.0 9.2e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family BLF1 PF17752.1 PRP79953.1 - 0.051 12.9 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 Burkholderia lethal factor 1 Big_9 PF17963.1 PRP79954.1 - 1e-12 48.6 171.2 2.7e-05 24.8 4.5 21.7 16 7 3 19 19 19 8 Bacterial Ig domain Cadherin_3 PF16184.5 PRP79954.1 - 2.6e-11 43.5 20.1 0.005 16.8 0.0 9.8 10 0 0 10 10 10 3 Cadherin-like Cadherin_4 PF17803.1 PRP79954.1 - 0.0055 17.3 3.9 0.0055 17.3 3.9 18.4 17 2 0 17 17 17 4 Bacterial cadherin-like domain Fil_haemagg_2 PF13332.6 PRP79954.1 - 0.86 9.7 4.4 0.65 10.1 1.3 2.5 2 0 0 2 2 2 0 Hemagglutinin repeat COG4 PF08318.12 PRP79957.1 - 4.4e-34 118.1 8.8 1e-29 103.7 0.0 3.8 5 0 0 5 5 5 2 COG4 transport protein DUF498 PF04430.14 PRP79958.1 - 7.1e-26 90.4 0.0 1e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Aminotran_3 PF00202.21 PRP79959.1 - 1.5e-94 317.0 0.0 1.8e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.25 PRP79960.1 - 1.8e-61 207.8 0.0 9.3e-61 205.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79960.1 - 2.8e-32 112.0 0.0 4.2e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP79960.1 - 1.8e-09 37.3 0.0 3.8e-09 36.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP79960.1 - 1.5e-05 24.4 0.1 2.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP79960.1 - 2.7e-05 24.2 0.3 0.0013 18.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP79960.1 - 0.0011 17.9 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 PRP79960.1 - 0.0012 18.0 0.1 0.0022 17.1 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 PRP79960.1 - 0.022 13.7 0.1 0.034 13.1 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 PRP79960.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 PRP79960.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 UCH PF00443.29 PRP79961.1 - 2.6e-52 177.9 0.8 4.1e-52 177.2 0.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PRP79961.1 - 3e-15 56.3 10.6 3e-15 56.3 10.6 2.6 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 PRP79961.1 - 3.1e-13 50.0 3.1 3.1e-13 50.0 3.1 3.2 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.7 PRP79961.1 - 4 7.6 12.5 15 5.7 0.3 4.2 3 1 0 3 3 3 0 Double zinc ribbon YrhK PF14145.6 PRP79962.1 - 2.4e-11 43.3 14.0 6.6e-08 32.3 3.3 2.9 3 0 0 3 3 3 2 YrhK-like protein Orn_Arg_deC_N PF02784.16 PRP79963.1 - 3.1e-70 236.4 0.0 3.9e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PRP79963.1 - 6.3e-19 68.0 0.0 1e-18 67.4 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ig_mannosidase PF17753.1 PRP79964.1 - 3.4e-19 68.4 0.1 9.6e-19 66.9 0.1 1.8 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 PRP79964.1 - 1.1e-10 42.0 0.2 4.7e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 PRP79964.1 - 1.4e-08 35.4 0.6 4.1e-08 33.9 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 PRP79964.1 - 5.6e-06 26.4 0.3 1.5e-05 24.9 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 PRP79964.1 - 0.00027 20.2 0.0 0.0013 18.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain TIMELESS_C PF05029.13 PRP79965.1 - 0.04 13.1 0.0 0.04 13.1 0.0 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region ACOX PF01756.19 PRP79966.1 - 8.4e-55 185.1 0.1 1.3e-54 184.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 PRP79966.1 - 1.1e-22 80.9 0.3 2.2e-22 80.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 PRP79966.1 - 7.1e-11 42.2 0.0 2.4e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 PRP79966.1 - 0.067 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PRP79966.1 - 0.1 13.3 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain SRP9-21 PF05486.12 PRP79967.1 - 3e-13 50.0 1.7 2.4e-11 43.9 1.7 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) FH2 PF02181.23 PRP79969.1 - 1.9e-72 244.5 4.2 3.6e-72 243.6 4.2 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PRP79969.1 - 5.6e-27 94.6 1.9 2.8e-26 92.4 0.1 2.8 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP79969.1 - 4.7e-20 72.0 0.2 1.5e-19 70.3 0.2 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain U3_snoRNA_assoc PF08297.11 PRP79969.1 - 1.4 9.7 8.0 5 7.9 2.5 3.2 3 0 0 3 3 3 0 U3 snoRNA associated Mito_fiss_reg PF05308.11 PRP79969.1 - 2.5 8.1 6.9 2 8.5 3.5 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator RRM_1 PF00076.22 PRP79970.1 - 1.1e-17 63.6 0.1 1.8e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP79970.1 - 0.043 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 PRP79972.1 - 1.7e-18 66.3 41.7 2.7e-05 24.5 4.2 4.2 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 PRP79972.1 - 2.7e-06 27.0 29.3 0.0031 17.3 1.2 5.3 5 1 0 5 5 5 3 CCCH-type zinc finger zf-CCCH PF00642.24 PRP79972.1 - 8.9e-06 25.5 37.3 0.015 15.2 3.4 6.9 6 2 1 7 7 7 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP79972.1 - 0.0038 17.2 37.4 0.017 15.2 1.3 6.1 6 2 2 8 8 8 4 Zinc finger domain zf-CCCH_3 PF15663.5 PRP79972.1 - 0.078 13.2 9.5 0.076 13.2 2.9 3.0 1 1 1 2 2 2 0 Zinc-finger containing family BTB_2 PF02214.22 PRP79973.1 - 3.5e-07 30.5 0.0 1.5e-06 28.5 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain Pkinase PF00069.25 PRP79974.1 - 1e-76 257.8 0.0 1.2e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79974.1 - 7.7e-37 127.0 0.0 8.8e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP79974.1 - 9.4e-06 25.1 0.0 8.4e-05 22.0 0.0 2.0 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 PRP79974.1 - 7e-05 22.5 0.0 0.00018 21.1 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 PRP79974.1 - 0.00024 20.5 0.0 0.00039 19.8 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP79974.1 - 0.001 19.0 0.1 0.15 11.9 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP79974.1 - 0.0087 15.0 0.1 0.012 14.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Ank_2 PF12796.7 PRP79975.1 - 1.5e-12 47.9 1.0 0.0016 19.0 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79975.1 - 2.1e-07 31.4 4.4 0.33 11.6 0.0 5.9 1 1 5 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP79975.1 - 1.1e-05 25.4 4.3 3.1 8.7 0.1 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 PRP79975.1 - 4.8e-05 23.6 2.2 0.48 10.8 0.0 5.2 4 2 2 6 6 6 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP79975.1 - 0.0012 18.7 2.8 0.0036 17.2 1.8 2.2 2 0 0 2 2 2 1 F-box-like Abhydrolase_4 PF08386.10 PRP79975.1 - 0.2 11.8 1.1 1.3 9.2 0.7 2.5 2 1 0 2 2 2 0 TAP-like protein Ank_2 PF12796.7 PRP79976.1 - 1.7e-19 70.2 1.1 2e-09 37.9 0.3 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP79976.1 - 1.2e-16 59.1 0.1 0.0033 17.8 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 PRP79976.1 - 1.6e-16 59.9 0.2 0.00087 19.6 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 PRP79976.1 - 1.9e-15 56.7 0.3 3.9e-05 23.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP79976.1 - 7.4e-15 55.1 0.1 0.0037 17.8 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Cnd3 PF12719.7 PRP79977.1 - 5.4e-46 157.1 5.7 2.1e-45 155.2 5.7 2.1 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 PRP79977.1 - 3.5e-06 26.8 0.7 2.7 8.5 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 PRP79977.1 - 5.3e-06 26.7 1.1 0.022 15.2 0.0 3.8 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 PRP79977.1 - 8e-05 22.7 8.6 0.13 12.3 0.2 4.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Pectate_lyase_3 PF12708.7 PRP79978.1 - 6.8e-88 294.1 18.1 9.2e-74 247.9 10.2 3.0 3 0 0 3 3 2 2 Pectate lyase superfamily protein TPR_1 PF00515.28 PRP79978.1 - 2.7e-21 74.4 11.1 1.4e-08 34.2 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP79978.1 - 2.3e-17 61.6 10.8 3.5e-06 26.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP79978.1 - 1.9e-14 53.0 12.7 1.4e-07 31.1 3.7 4.4 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 PRP79978.1 - 1.1e-12 47.0 11.4 1.6e-05 24.8 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat SGTA_dimer PF16546.5 PRP79978.1 - 1.2e-10 41.0 0.6 4e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_16 PF13432.6 PRP79978.1 - 6.9e-08 33.0 1.0 0.00028 21.5 0.9 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP79978.1 - 1.3e-07 31.8 4.7 0.00019 21.6 1.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP79978.1 - 2.1e-07 30.9 4.6 0.00085 19.5 0.6 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat End_N_terminal PF12218.8 PRP79978.1 - 2.6e-06 27.0 0.7 0.076 12.7 0.4 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase TPR_14 PF13428.6 PRP79978.1 - 2.9e-06 27.6 0.4 0.27 12.2 0.0 4.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP79978.1 - 4.9e-05 23.1 0.6 0.3 11.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SGT1 PF07093.11 PRP79978.1 - 0.00017 20.2 0.0 0.00027 19.5 0.0 1.2 1 0 0 1 1 1 1 SGT1 protein TPR_9 PF13371.6 PRP79978.1 - 0.00023 21.2 0.0 0.0007 19.7 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 PRP79978.1 - 0.00033 20.0 0.4 0.22 10.7 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP79978.1 - 0.00066 20.1 4.4 0.02 15.4 0.0 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP79978.1 - 0.0016 18.9 0.2 0.36 11.6 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 PRP79978.1 - 0.0018 17.2 1.1 0.0032 16.5 1.1 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 PRP79978.1 - 0.0051 17.0 3.1 0.014 15.7 3.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 PRP79978.1 - 0.011 15.8 2.9 1.3 9.2 0.4 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 PRP79978.1 - 0.011 16.2 0.1 0.033 14.6 0.1 1.8 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 PRP79978.1 - 0.012 15.5 4.4 0.59 10.1 0.4 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Fascin PF06268.13 PRP79978.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 Fascin domain Fis1_TPR_C PF14853.6 PRP79978.1 - 0.043 13.9 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.23 PRP79978.1 - 0.089 12.0 2.8 1.5 7.9 0.4 2.4 2 1 0 2 2 2 0 FAT domain SHNi-TPR PF10516.9 PRP79978.1 - 0.1 12.1 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 SHNi-TPR GerD PF17898.1 PRP79978.1 - 0.49 10.4 8.0 3.8 7.5 8.0 2.3 1 1 0 1 1 1 0 Spore germination GerD central core domain XPC-binding PF09280.11 PRP79978.1 - 1.1 9.1 6.7 4.8 7.0 6.0 2.3 1 1 1 2 2 2 0 XPC-binding domain STI1 PF17830.1 PRP79978.1 - 1.8 8.6 21.7 10 6.2 12.7 2.7 1 1 1 2 2 2 0 STI1 domain Ank_2 PF12796.7 PRP79980.1 - 6.4e-42 142.0 6.5 3.4e-12 46.8 0.0 5.3 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP79980.1 - 1.4e-35 121.2 8.9 6.1e-08 33.1 0.0 7.3 3 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP79980.1 - 7.2e-28 95.8 9.4 5.3e-05 23.5 0.2 7.4 7 1 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 PRP79980.1 - 1.9e-23 82.2 3.8 5.4e-08 32.9 0.1 6.1 5 1 1 6 6 6 4 Ankyrin repeats (many copies) BTB PF00651.31 PRP79980.1 - 8.2e-22 77.5 0.1 2e-08 34.4 0.0 3.8 3 1 0 3 3 3 3 BTB/POZ domain Ank_3 PF13606.6 PRP79980.1 - 1e-21 74.7 8.9 0.0014 19.0 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat DUF4637 PF15470.6 PRP79980.1 - 0.061 13.1 2.3 0.12 12.1 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) AMP-binding PF00501.28 PRP79981.1 - 1.4e-99 333.6 0.0 2.1e-99 333.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RVT_1 PF00078.27 PRP79985.1 - 3.3e-20 72.6 0.0 3.7e-19 69.1 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3902 PF13042.6 PRP79985.1 - 0.00036 20.2 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3902) Glyco_hydro_16 PF00722.21 PRP79989.1 - 5.8e-15 55.2 0.7 5.8e-15 55.2 0.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 UPF0176_N PF17773.1 PRP79989.1 - 7.4e-12 45.5 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 PRP79989.1 - 1.2e-09 38.3 7.9 1.2e-09 38.3 7.9 2.4 2 0 0 2 2 2 1 Rhodanase C-terminal Rhodanese PF00581.20 PRP79989.1 - 2.5e-06 27.9 0.0 7.7e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Carb_bind PF10645.9 PRP79989.1 - 0.0089 16.2 7.1 0.024 14.9 7.1 1.7 1 0 0 1 1 1 1 Carbohydrate binding PT PF04886.12 PRP79989.1 - 0.24 11.0 45.7 0.15 11.6 26.2 2.5 1 1 1 2 2 2 0 PT repeat Trypan_PARP PF05887.11 PRP79989.1 - 0.38 10.7 6.1 0.72 9.8 6.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Thymidylate_kin PF02223.17 PRP79990.1 - 2.7e-44 151.1 0.0 3.1e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 PRP79990.1 - 0.0017 18.2 0.3 0.015 15.1 0.3 2.1 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_14 PF13173.6 PRP79990.1 - 0.0078 16.2 0.0 0.39 10.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain LIP1 PF15904.5 PRP79990.1 - 0.024 15.0 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 AAA_5 PF07728.14 PRP79990.1 - 0.03 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 PRP79990.1 - 0.065 12.7 0.1 5 6.5 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 PRP79990.1 - 0.094 13.3 0.0 0.2 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain GAS PF13851.6 PRP79991.1 - 0.003 16.9 22.5 0.003 16.9 22.5 2.9 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding zf-CCCH_6 PF18585.1 PRP79991.1 - 0.053 13.4 0.9 0.4 10.6 0.9 2.6 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 PMEI PF04043.15 PRP79991.1 - 1.6 9.0 9.8 0.19 12.0 4.8 1.9 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Myosin_head PF00063.21 PRP79992.1 - 2.3e-262 872.2 0.1 2.8e-262 871.9 0.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 PRP79992.1 - 2.7e-43 147.8 1.0 4.4e-43 147.1 1.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 PRP79992.1 - 1.9e-13 50.1 0.1 6.2e-13 48.4 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP79992.1 - 3.9e-13 48.8 0.2 1e-12 47.5 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP79992.1 - 4.6e-09 35.8 0.0 1.2e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain TsaE PF02367.17 PRP79992.1 - 0.036 14.1 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PRP79992.1 - 0.085 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PRP79992.1 - 0.12 12.6 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PRP79992.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF92 PF01940.16 PRP79993.1 - 3.9e-79 265.4 4.1 4.5e-79 265.2 4.1 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Tetraspanin PF00335.20 PRP79993.1 - 0.035 13.8 0.5 0.061 13.0 0.5 1.5 1 0 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.6 PRP79993.1 - 0.13 11.9 6.7 3.1 7.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) NQR2_RnfD_RnfE PF03116.15 PRP79993.1 - 0.28 10.6 6.2 0.054 12.9 1.1 2.1 3 0 0 3 3 3 0 NQR2, RnfD, RnfE family Hyccin PF09790.9 PRP79994.1 - 3.2e-38 131.6 0.0 1.1e-37 129.9 0.0 1.7 1 1 0 1 1 1 1 Hyccin PGM_PMM_II PF02879.16 PRP79994.1 - 0.071 13.7 0.0 0.14 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Ras PF00071.22 PRP79995.1 - 4.4e-40 136.9 0.1 5.8e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP79995.1 - 1.1e-27 96.6 0.1 2.9e-27 95.3 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP79995.1 - 3.4e-12 46.2 0.1 4.9e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP79995.1 - 0.00016 21.1 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP79995.1 - 0.00038 20.1 1.1 0.055 13.0 1.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PRP79995.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PRP79995.1 - 0.0025 17.9 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 PRP79995.1 - 0.011 15.5 0.1 0.38 10.5 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 PRP79995.1 - 0.031 13.8 0.0 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 PRP79995.1 - 0.082 11.7 0.0 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) TniB PF05621.11 PRP79995.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein TPR_12 PF13424.6 PRP79996.1 - 3.3e-14 52.9 2.6 1e-10 41.8 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP79996.1 - 0.00015 21.6 0.7 0.41 10.9 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP79996.1 - 0.00017 21.0 1.9 0.00072 19.0 1.5 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 PRP79996.1 - 0.00032 20.7 0.8 1.8 9.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP79996.1 - 0.00059 20.4 1.1 0.3 12.0 0.1 3.7 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP79996.1 - 0.0024 17.6 0.6 0.23 11.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP79996.1 - 0.036 13.9 2.2 4.2 7.4 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TIP120 PF08623.10 PRP79996.1 - 0.047 13.5 5.9 2.9 7.7 1.0 2.9 3 1 0 3 3 3 0 TATA-binding protein interacting (TIP20) TPR_6 PF13174.6 PRP79996.1 - 0.047 14.3 1.3 68 4.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP79996.1 - 0.06 14.0 1.8 5.2 7.8 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat EzrA PF06160.12 PRP79996.1 - 0.066 11.4 8.2 0.3 9.2 1.0 2.2 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA SlyX PF04102.12 PRP79996.1 - 0.46 11.1 4.2 13 6.4 0.9 2.8 2 0 0 2 2 2 0 SlyX DUF948 PF06103.11 PRP79996.1 - 3.3 8.0 5.6 23 5.3 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 PRP79997.1 - 1.1e-69 234.8 0.0 1.5e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP79997.1 - 3.5e-29 101.9 0.0 5e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PRP79997.1 - 0.037 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 PRP79997.1 - 0.047 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP79997.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family JAMP PF05571.12 PRP79998.1 - 1.6e-48 165.8 24.3 2.3e-48 165.3 24.3 1.2 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein Claudin_2 PF13903.6 PRP79999.1 - 0.00086 19.1 3.9 0.0014 18.4 3.9 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction COX14 PF14880.6 PRP79999.1 - 0.14 12.1 3.1 2.6 8.0 0.0 2.6 3 0 0 3 3 3 0 Cytochrome oxidase c assembly DUF3413 PF11893.8 PRP79999.1 - 0.15 11.2 3.3 0.25 10.5 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Virul_fac_BrkB PF03631.15 PRP79999.1 - 0.97 9.0 9.3 1.3 8.5 6.4 2.3 2 1 0 2 2 2 0 Virulence factor BrkB Pex16 PF08610.10 PRP80000.1 - 2.1e-53 181.6 3.2 2.3e-53 181.4 3.2 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) TTL PF03133.15 PRP80001.1 - 1.3e-80 270.7 0.4 1.9e-80 270.2 0.4 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PRP80001.1 - 1.3e-05 24.6 0.1 0.0018 17.6 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PRP80001.1 - 7e-05 22.2 0.0 0.059 12.6 0.0 3.2 3 0 0 3 3 3 1 Sugar-transfer associated ATP-grasp DUF1660 PF07874.11 PRP80001.1 - 0.15 12.6 1.4 15 6.2 0.1 2.8 2 0 0 2 2 2 0 Prophage protein (DUF1660) UPF0565 PF10561.9 PRP80003.1 - 1e-23 84.1 0.2 5.8e-11 42.1 0.0 3.1 2 1 1 3 3 3 3 Uncharacterised protein family UPF0565 NUDIX PF00293.28 PRP80004.1 - 9.3e-12 45.1 0.3 1e-11 45.0 0.3 1.0 1 0 0 1 1 1 1 NUDIX domain Cupin_8 PF13621.6 PRP80005.1 - 5.9e-39 134.3 2.6 1.6e-38 132.9 2.5 1.7 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 PRP80005.1 - 3.6e-16 59.5 0.9 5.7e-16 58.9 0.9 1.3 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PRP80005.1 - 0.024 15.1 0.9 0.05 14.0 0.1 2.0 2 0 0 2 2 2 0 JmjC domain, hydroxylase ThaI PF15514.6 PRP80006.1 - 0.098 12.3 0.0 0.098 12.3 0.0 1.0 1 0 0 1 1 1 0 Restriction endonuclease ThaI PAP2 PF01569.21 PRP80006.1 - 0.099 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 PAP2 superfamily HA PF03457.14 PRP80007.1 - 1.7e-18 66.7 2.8 4.4e-18 65.4 2.8 1.7 1 0 0 1 1 1 1 Helicase associated domain FAT PF02259.23 PRP80008.1 - 8.9e-38 130.4 9.6 8.9e-38 130.4 9.6 2.3 2 0 0 2 2 2 1 FAT domain TPR_14 PF13428.6 PRP80008.1 - 0.026 15.3 0.0 0.3 12.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SAND PF01342.21 PRP80008.1 - 0.099 12.4 0.2 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 SAND domain Sec7_N PF12783.7 PRP80008.1 - 6.8 6.6 12.8 2.1 8.2 0.1 5.8 7 0 0 7 7 7 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CEP19 PF14933.6 PRP80009.1 - 9e-21 74.9 0.0 1.2e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein EF-hand_6 PF13405.6 PRP80010.1 - 5.9e-14 50.7 4.1 1.7e-07 30.6 0.1 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PRP80010.1 - 2.7e-13 48.4 8.8 8.9e-08 31.2 0.1 3.9 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 PRP80010.1 - 4.7e-11 41.7 4.2 1e-05 24.8 0.1 3.1 2 0 0 2 2 2 2 EF hand DIX PF00778.17 PRP80010.1 - 6.9e-11 41.8 0.3 3.8e-10 39.5 0.2 2.2 2 0 0 2 2 2 1 DIX domain EF-hand_7 PF13499.6 PRP80010.1 - 1e-10 41.9 2.5 1.3e-05 25.5 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP80010.1 - 3.9e-10 39.4 5.4 4.8e-05 23.1 2.6 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 PRP80010.1 - 6.7e-05 23.1 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain KAP PF05804.12 PRP80010.1 - 0.12 10.5 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) EF-hand_4 PF12763.7 PRP80010.1 - 0.16 12.0 2.0 15 5.6 0.0 3.0 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand AAA PF00004.29 PRP80011.1 - 2.7e-53 179.9 0.0 7.1e-41 139.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 PRP80011.1 - 3.5e-25 88.2 0.1 1e-24 86.8 0.1 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 PRP80011.1 - 1.9e-13 51.2 4.0 0.00018 22.0 0.0 4.8 2 2 2 4 4 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 PRP80011.1 - 6.2e-10 38.7 0.7 2e-08 33.9 0.0 2.7 3 0 0 3 3 2 1 AAA+ lid domain AAA_22 PF13401.6 PRP80011.1 - 7.4e-09 36.0 1.0 0.048 13.9 0.1 4.8 2 2 1 3 3 3 2 AAA domain AAA_33 PF13671.6 PRP80011.1 - 2.8e-08 34.0 0.1 0.0023 18.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 PRP80011.1 - 4.3e-07 30.0 0.0 0.0028 17.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 PRP80011.1 - 1.6e-06 28.1 0.1 0.0091 15.8 0.0 2.7 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 PRP80011.1 - 1.6e-06 28.0 0.0 0.0072 16.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.14 PRP80011.1 - 2.3e-06 27.9 0.0 0.053 13.6 0.0 3.8 4 0 0 4 4 4 2 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 PRP80011.1 - 2.6e-06 28.0 0.0 0.046 14.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PRP80011.1 - 5.4e-06 26.4 2.3 0.026 14.4 0.1 4.1 3 1 0 3 3 3 2 NACHT domain AAA_5 PF07728.14 PRP80011.1 - 1.2e-05 25.3 0.2 0.34 10.9 0.0 4.1 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) Torsin PF06309.11 PRP80011.1 - 9.1e-05 22.6 0.0 0.0016 18.5 0.0 2.4 2 0 0 2 2 2 1 Torsin Zeta_toxin PF06414.12 PRP80011.1 - 0.00013 21.3 0.0 0.49 9.6 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin TsaE PF02367.17 PRP80011.1 - 0.00019 21.4 0.0 0.11 12.5 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 PRP80011.1 - 0.00028 20.2 0.0 0.68 9.1 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 PRP80011.1 - 0.00037 20.9 0.1 0.13 12.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 PRP80011.1 - 0.00068 18.9 0.1 1.4 8.0 0.1 3.0 2 1 1 3 3 3 2 NB-ARC domain Bac_DnaA PF00308.18 PRP80011.1 - 0.00073 19.4 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein RNA_helicase PF00910.22 PRP80011.1 - 0.001 19.4 0.0 1.3 9.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Sigma54_activat PF00158.26 PRP80011.1 - 0.0013 18.4 0.0 0.19 11.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 PRP80011.1 - 0.0015 18.3 0.0 0.0058 16.4 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 PRP80011.1 - 0.0019 18.2 0.0 0.44 10.4 0.0 3.7 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 PRP80011.1 - 0.0051 16.4 0.8 0.67 9.5 0.1 3.3 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PRP80011.1 - 0.0052 17.3 0.0 3.7 8.1 0.0 3.3 3 0 0 3 3 2 1 ABC transporter Mg_chelatase PF01078.21 PRP80011.1 - 0.0056 16.1 0.0 0.29 10.5 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 PRP80011.1 - 0.006 15.8 0.0 0.027 13.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 PRP80011.1 - 0.011 15.5 0.1 4.4 7.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 PRP80011.1 - 0.017 14.3 0.0 5.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AFG1_ATPase PF03969.16 PRP80011.1 - 0.02 13.8 0.1 0.17 10.7 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase AAA_28 PF13521.6 PRP80011.1 - 0.034 14.4 0.0 1 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PRP80011.1 - 0.073 12.1 0.0 6.9 5.6 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein Hydin_ADK PF17213.3 PRP80011.1 - 8 6.7 6.8 15 5.8 0.0 3.8 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Copine PF07002.16 PRP80012.1 - 4.7e-62 209.3 0.0 6.5e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 PRP80012.1 - 1.9e-23 82.7 0.0 4.2e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 PRP80012.1 - 4.4e-07 30.2 0.0 1.3e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus TINF2_N PF14973.6 PRP80014.1 - 0.46 10.8 1.9 0.47 10.8 0.1 1.9 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Chromo PF00385.24 PRP80015.1 - 1e-13 50.9 0.0 1.3e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP80015.1 - 0.05 13.8 1.1 0.053 13.7 0.2 1.5 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Ubiquitin_4 PF18036.1 PRP80016.1 - 2.3e-12 46.8 0.2 3.6e-12 46.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF1084 PF06454.11 PRP80017.1 - 2.5e-13 50.0 16.0 1e-09 38.2 13.4 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) YoqO PF14037.6 PRP80017.1 - 0.12 12.9 12.3 0.12 13.0 7.4 2.7 2 1 0 2 2 2 0 YoqO-like protein EptA_B_N PF08019.12 PRP80017.1 - 9.6 6.1 14.8 0.15 11.9 3.5 3.2 2 1 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB tRNA_anti-codon PF01336.25 PRP80019.1 - 6.3e-07 29.3 0.1 1.3e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 PRP80019.1 - 0.021 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 RecQ-mediated genome instability protein 2 RPA_C PF08784.11 PRP80019.1 - 0.04 14.6 0.2 0.091 13.4 0.2 1.6 1 0 0 1 1 1 0 Replication protein A C terminal FAM117 PF15388.6 PRP80019.1 - 0.071 12.5 0.2 0.1 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein Family FAM117 DUF4011 PF13195.6 PRP80019.1 - 0.076 12.9 0.1 0.59 10.0 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4011) DUF4539 PF15072.6 PRP80019.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) zf-C3HC4_3 PF13920.6 PRP80020.1 - 3.2e-12 46.1 9.6 3.2e-12 46.1 9.6 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) CBM_20 PF00686.19 PRP80020.1 - 1.3e-10 41.0 0.1 5.1e-10 39.1 0.1 2.0 1 1 0 1 1 1 1 Starch binding domain Prok-RING_4 PF14447.6 PRP80020.1 - 5.4e-05 23.0 10.2 5.4e-05 23.0 10.2 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 UPF0262 PF06793.12 PRP80020.1 - 0.052 13.7 0.5 0.69 10.0 0.8 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0262) K-box PF01486.17 PRP80020.1 - 0.1 12.8 4.0 0.27 11.4 4.0 1.8 1 0 0 1 1 1 0 K-box region Vma12 PF11712.8 PRP80020.1 - 0.2 11.7 0.1 0.2 11.7 0.1 1.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CK2S PF15011.6 PRP80020.1 - 0.29 11.0 4.5 7.2 6.5 0.7 2.2 1 1 1 2 2 2 0 Casein Kinase 2 substrate zf-C3HC4_2 PF13923.6 PRP80020.1 - 3.4 7.6 21.9 0.054 13.3 12.0 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2321 PF10083.9 PRP80020.1 - 4.7 6.8 7.9 1.1 8.8 3.4 2.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) DEAD PF00270.29 PRP80021.1 - 4.6e-47 160.0 0.5 9.3e-47 159.0 0.5 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP80021.1 - 1.8e-24 86.2 0.1 2.5e-23 82.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PRP80021.1 - 4.1e-20 71.8 0.1 8.5e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Neur_chan_memb PF02932.16 PRP80021.1 - 1.1 9.3 8.6 2.1 8.4 8.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleo_P87 PF07267.11 PRP80021.1 - 6.6 5.5 16.3 11 4.7 16.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 His_Phos_1 PF00300.22 PRP80022.1 - 4.4e-57 192.9 0.0 5e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase_Tyr PF07714.17 PRP80023.1 - 1.9e-51 174.8 0.0 2.6e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80023.1 - 1.3e-48 165.7 0.0 1.9e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP80023.1 - 1.4e-11 44.3 0.1 3.2e-11 43.2 0.1 1.7 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 PRP80023.1 - 1.2e-06 29.0 1.2 2.9e-06 27.8 0.3 2.1 2 0 0 2 2 2 1 PH domain Kdo PF06293.14 PRP80023.1 - 5e-05 22.7 0.0 8.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_11 PF15413.6 PRP80023.1 - 0.0013 19.1 1.7 0.0017 18.7 0.3 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_15 PF17339.2 PRP80023.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 PH domain PH_9 PF15410.6 PRP80023.1 - 0.17 12.3 0.1 0.37 11.2 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain RhoGAP PF00620.27 PRP80025.1 - 2.8e-22 79.2 0.0 3.4e-20 72.4 0.0 2.5 1 1 0 1 1 1 1 RhoGAP domain SH3_1 PF00018.28 PRP80025.1 - 4e-07 29.5 0.3 1.5e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 PRP80025.1 - 4.1e-07 29.8 0.0 1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RPEL PF02755.15 PRP80025.1 - 3.7e-06 26.5 1.0 1.2e-05 24.9 1.0 2.0 1 0 0 1 1 1 1 RPEL repeat TIG PF01833.24 PRP80025.1 - 4.6e-06 26.6 0.0 1.7e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 IPT/TIG domain SH3_2 PF07653.17 PRP80025.1 - 0.00074 19.1 0.0 0.0019 17.8 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain COX5B PF01215.19 PRP80025.1 - 0.055 13.2 0.0 3 7.5 0.0 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Vb LRR_4 PF12799.7 PRP80026.1 - 5e-28 96.7 27.4 1.9e-09 37.6 0.3 6.2 6 0 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP80026.1 - 4.1e-16 58.5 21.4 1.9e-06 27.5 3.7 5.6 1 1 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 PRP80026.1 - 7.8e-13 48.3 11.5 2e-05 24.1 0.8 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 PRP80026.1 - 7.5e-07 28.7 12.4 1.6 9.0 0.2 6.7 7 0 0 7 7 7 4 Leucine Rich repeat Rbsn PF11464.8 PRP80026.1 - 0.44 10.3 0.1 0.44 10.3 0.1 2.5 3 0 0 3 3 3 0 Rabenosyn Rab binding domain PP1_inhibitor PF05361.12 PRP80026.1 - 0.77 9.8 4.1 0.84 9.6 1.0 2.4 1 1 1 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor DIE2_ALG10 PF04922.12 PRP80027.1 - 5.8e-106 355.1 26.0 7.7e-106 354.7 26.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family PMT_2 PF13231.6 PRP80027.1 - 3.9 7.7 33.8 0.37 11.0 3.5 3.9 3 1 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase RhoGAP PF00620.27 PRP80029.1 - 1.3e-05 25.1 0.1 0.00011 22.1 0.0 2.4 2 1 0 2 2 2 1 RhoGAP domain DUF4521 PF15021.6 PRP80030.1 - 0.03 14.3 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) TMEM151 PF14857.6 PRP80031.1 - 2.2e-16 59.8 4.8 4.2e-16 58.9 4.8 1.4 1 0 0 1 1 1 1 TMEM151 family Lyase_8 PF02278.18 PRP80032.1 - 1.3e-47 162.5 0.6 1.3e-47 162.5 0.6 2.4 4 0 0 4 4 4 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 PRP80032.1 - 4.8e-16 58.6 0.8 1.7e-15 56.8 0.8 1.8 1 1 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 PRP80032.1 - 2.3e-12 47.2 0.8 8.5e-12 45.4 0.8 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain He_PIG PF05345.12 PRP80032.1 - 0.076 13.2 1.4 0.49 10.6 1.4 2.5 1 0 0 1 1 1 0 Putative Ig domain DUF5608 PF18356.1 PRP80032.1 - 0.13 12.3 0.1 0.93 9.5 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5608) TrmE_N PF10396.9 PRP80033.1 - 3.7e-33 114.3 0.0 7.1e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 PRP80033.1 - 1.8e-30 106.7 0.0 6.3e-29 101.6 0.0 2.2 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 PRP80033.1 - 6.8e-21 74.5 0.0 1.7e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP80033.1 - 4e-07 29.7 0.0 8.4e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PRP80033.1 - 2.2e-06 27.9 0.0 4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 PRP80033.1 - 0.00015 21.7 0.0 0.21 11.5 0.0 2.9 1 1 2 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 PRP80033.1 - 0.0021 18.3 0.0 0.0054 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PRP80033.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 PRP80033.1 - 0.022 15.3 0.1 0.064 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1_Xtn PF16897.5 PRP80033.1 - 0.057 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 PRP80033.1 - 0.058 13.8 0.0 1 9.7 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.27 PRP80033.1 - 0.084 12.4 0.0 8.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.19 PRP80033.1 - 0.11 12.0 0.3 8.8 5.9 0.3 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LIM PF00412.22 PRP80034.1 - 4.6e-53 177.3 34.7 1.1e-15 57.5 3.7 4.1 4 0 0 4 4 4 4 LIM domain Calpain_inhib PF00748.19 PRP80034.1 - 0.0059 17.1 3.7 0.013 16.0 3.7 1.6 1 0 0 1 1 1 1 Calpain inhibitor DUF3235 PF11574.8 PRP80034.1 - 0.2 12.6 8.4 0.46 11.4 8.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) TMEM135_C_rich PF15982.5 PRP80035.1 - 1e-21 77.9 0.1 5.9e-21 75.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 PRP80035.1 - 0.016 15.6 6.8 0.095 13.1 0.0 2.7 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Occludin_ELL PF07303.13 PRP80036.1 - 8.7e-08 32.8 11.4 8.7e-08 32.8 11.4 3.4 3 0 0 3 3 3 1 Occludin homology domain ELL PF10390.9 PRP80036.1 - 9.5e-05 22.0 14.3 9.5e-05 22.0 14.3 4.8 1 1 1 2 2 2 1 RNA polymerase II elongation factor ELL ANAPC4_WD40 PF12894.7 PRP80037.1 - 5e-08 33.1 1.4 0.0028 17.9 0.0 6.2 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP80037.1 - 5.2e-05 23.9 0.3 0.14 13.0 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 PRP80037.1 - 0.0054 15.8 0.1 0.0054 15.8 0.1 3.2 3 0 0 3 3 3 1 Coatomer WD associated region Clathrin PF00637.20 PRP80037.1 - 0.012 15.5 1.5 0.33 10.8 0.1 2.8 1 1 1 2 2 2 0 Region in Clathrin and VPS EGF_2 PF07974.13 PRP80037.1 - 0.028 14.8 3.5 0.09 13.2 3.5 1.9 1 0 0 1 1 1 0 EGF-like domain Cript PF10235.9 PRP80037.1 - 0.036 14.6 0.5 0.12 12.9 0.5 1.9 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT PD40 PF07676.12 PRP80037.1 - 0.041 13.8 0.0 0.98 9.4 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DZR PF12773.7 PRP80037.1 - 0.89 9.6 5.8 2.5 8.2 5.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon Vps39_1 PF10366.9 PRP80037.1 - 1 9.7 4.6 4.2 7.7 1.6 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 PRP80037.1 - 1.7 9.0 11.4 1.9 8.8 1.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn-ribbon_8 PF09723.10 PRP80037.1 - 4.2 7.6 7.2 9.7 6.4 2.6 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Peptidase_M28 PF04389.17 PRP80039.1 - 5.4e-24 85.0 0.0 2.3e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 SnoaL_4 PF13577.6 PRP80039.1 - 0.19 11.9 0.5 0.38 10.9 0.1 1.7 2 0 0 2 2 2 0 SnoaL-like domain Pkinase_Tyr PF07714.17 PRP80040.1 - 1.1e-78 264.1 0.0 1.6e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80040.1 - 6.3e-53 179.8 0.0 9.7e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP80040.1 - 1.4e-37 127.2 49.8 9.7e-06 25.3 0.3 9.9 7 2 1 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 PRP80040.1 - 2e-28 98.0 55.2 1.8e-05 25.0 0.1 11.2 6 3 10 16 16 16 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP80040.1 - 4.8e-11 41.6 56.5 6.4 7.7 0.0 18.0 17 3 0 17 17 16 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP80040.1 - 8.7e-07 28.5 53.8 7.3 6.9 0.1 16.4 18 0 0 18 18 18 4 Leucine Rich repeat Pkinase_fungal PF17667.1 PRP80040.1 - 0.00071 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP80040.1 - 0.00072 19.0 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP80040.1 - 0.051 12.5 0.5 0.094 11.6 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 PRP80040.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vpu PF00558.19 PRP80040.1 - 0.13 12.1 0.4 0.3 10.9 0.4 1.5 1 0 0 1 1 1 0 Vpu protein Adeno_E3_CR2 PF02439.15 PRP80040.1 - 0.34 10.7 2.7 0.61 9.9 2.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 F-box-like PF12937.7 PRP80041.1 - 8.2e-05 22.4 0.0 0.00043 20.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP80041.1 - 0.0019 18.0 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain MORN PF02493.20 PRP80042.1 - 1.8e-08 33.8 4.7 0.001 18.8 0.2 2.8 3 0 0 3 3 3 2 MORN repeat PA14 PF07691.12 PRP80044.1 - 0.05 13.4 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 PA14 domain MORN PF02493.20 PRP80045.1 - 6.5e-94 302.6 191.9 2.7e-07 30.1 0.7 30.2 30 0 0 30 30 30 26 MORN repeat zf-C3HC4_3 PF13920.6 PRP80046.1 - 9.2e-07 28.6 6.4 7.7e-06 25.7 2.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MORN PF02493.20 PRP80046.1 - 0.0058 16.5 9.8 0.0076 16.1 0.3 3.8 3 1 0 3 3 3 1 MORN repeat PH_9 PF15410.6 PRP80046.1 - 0.056 13.8 0.3 0.21 12.0 0.3 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PilJ PF13675.6 PRP80046.1 - 0.062 13.3 14.2 0.79 9.8 3.6 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1917 PF08939.10 PRP80046.1 - 0.062 13.2 15.3 0.75 9.6 4.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) zf-UBP_var PF17807.1 PRP80046.1 - 0.11 12.3 1.9 9.9 6.0 0.1 2.8 2 0 0 2 2 2 0 Variant UBP zinc finger TetR_C_6 PF13977.6 PRP80046.1 - 0.21 11.8 4.6 15 5.9 0.2 3.3 3 1 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal KHA PF11834.8 PRP80046.1 - 0.27 11.3 1.8 34 4.6 0.1 3.2 3 1 0 3 3 3 0 KHA, dimerisation domain of potassium ion channel zf-RING_2 PF13639.6 PRP80046.1 - 0.51 10.7 9.2 0.052 13.9 3.2 2.3 2 0 0 2 2 2 0 Ring finger domain DUF4449 PF14613.6 PRP80046.1 - 1.4 9.0 24.3 4.1 7.5 8.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Taxilin PF09728.9 PRP80046.1 - 1.5 7.9 51.1 1.4 8.0 19.9 2.5 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF5631 PF18645.1 PRP80046.1 - 1.7 9.1 4.1 7.2 7.1 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5631) ERM PF00769.19 PRP80046.1 - 5.7 6.7 64.2 0.46 10.3 22.7 2.7 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Zn_clus PF00172.18 PRP80047.1 - 1.8e-07 31.1 11.6 3.5e-07 30.2 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.6 PRP80048.1 - 0.0044 17.7 0.0 0.01 16.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain TssR PF17643.1 PRP80048.1 - 0.01 13.9 0.0 0.014 13.4 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssR VWA PF00092.28 PRP80048.1 - 0.022 15.0 0.0 0.038 14.3 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain Glyco_hydro_63 PF03200.16 PRP80049.1 - 9.1e-159 529.3 11.9 6.3e-157 523.3 11.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 PRP80049.1 - 6.2e-52 176.9 1.0 6.2e-52 176.9 1.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain ZnuA PF01297.17 PRP80049.1 - 0.03 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Rubis-subs-bind PF09273.11 PRP80050.1 - 2.6e-19 70.2 0.6 4.7e-19 69.4 0.6 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 PRP80050.1 - 8.4e-05 23.0 0.0 0.00029 21.3 0.0 1.9 2 1 0 2 2 2 1 SET domain Claudin_2 PF13903.6 PRP80052.1 - 0.93 9.2 9.2 2.2 8.0 8.5 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PhyH PF05721.13 PRP80053.1 - 1.1e-46 159.7 0.0 1.7e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ELMO_CED12 PF04727.13 PRP80054.1 - 9.2e-29 100.8 0.0 1.8e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family Methyltransf_31 PF13847.6 PRP80055.1 - 3.3e-14 53.0 0.1 4.1e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP80055.1 - 1.1e-08 35.7 0.0 1.7e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP80055.1 - 1.1e-05 26.0 0.0 1.9e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP80055.1 - 2.7e-05 24.1 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP80055.1 - 0.00024 20.7 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 PRP80055.1 - 0.00033 21.3 0.0 0.00049 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 PRP80055.1 - 0.0054 15.9 0.0 0.0072 15.5 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_4 PF02390.17 PRP80055.1 - 0.11 11.9 0.1 1 8.8 0.0 2.0 1 1 1 2 2 2 0 Putative methyltransferase CAP_C PF08603.11 PRP80056.1 - 6.8e-45 152.5 6.7 1.3e-44 151.6 6.7 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Laminin_G_3 PF13385.6 PRP80056.1 - 0.00026 21.2 0.3 0.33 11.1 0.0 3.3 2 1 1 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily TBCC PF07986.12 PRP80056.1 - 0.007 16.1 0.7 0.015 15.0 0.7 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Synuclein PF01387.17 PRP80056.1 - 1.4 9.1 7.5 2.5 8.3 7.5 1.3 1 0 0 1 1 1 0 Synuclein Pkinase_Tyr PF07714.17 PRP80057.1 - 4.8e-23 81.8 0.0 4.4e-21 75.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80057.1 - 1.4e-12 47.5 0.0 2.8e-11 43.3 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Shadoo PF14999.6 PRP80057.1 - 1.5 8.9 5.1 0.2 11.8 0.6 1.8 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Pro-kuma_activ PF09286.11 PRP80058.1 - 2e-24 86.5 0.4 3.3e-24 85.8 0.4 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP80058.1 - 0.00016 21.0 2.7 0.00025 20.4 2.7 1.2 1 0 0 1 1 1 1 Subtilase family PP2C PF00481.21 PRP80059.1 - 3.4e-40 138.3 0.0 8e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP80059.1 - 0.00013 22.0 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 PRP80059.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Fer4_24 PF18109.1 PRP80059.1 - 0.1 12.9 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain PI3K_1B_p101 PF10486.9 PRP80063.1 - 4.4e-09 34.7 0.3 0.00092 17.1 0.1 2.7 2 1 0 2 2 2 2 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Laminin_G_3 PF13385.6 PRP80065.1 - 1.2e-37 129.4 2.4 1.5e-19 70.6 0.1 2.8 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily DUF4982 PF16355.5 PRP80065.1 - 0.0088 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Carb_bind PF10645.9 PRP80065.1 - 0.83 9.9 29.7 0.49 10.7 2.9 3.9 4 0 0 4 4 4 0 Carbohydrate binding Asp PF00026.23 PRP80067.1 - 1.7e-19 70.4 0.0 1.2e-18 67.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PRP80067.1 - 1.6e-09 38.2 0.9 3.2e-08 34.0 0.4 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 PRP80067.1 - 1.5e-05 24.8 0.0 4.2e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Pkinase PF00069.25 PRP80068.1 - 4.3e-41 141.0 0.0 6.2e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80068.1 - 1.1e-15 57.7 0.0 1.6e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP80068.1 - 9.2e-06 25.8 0.2 0.15 12.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP80068.1 - 3e-05 23.5 0.3 5e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP80068.1 - 0.025 13.9 0.0 0.062 12.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF3517 PF12030.8 PRP80068.1 - 0.12 11.3 0.1 0.4 9.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3517) AAA_16 PF13191.6 PRP80068.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain 2-Hacid_dh_C PF02826.19 PRP80069.1 - 1.1e-55 187.7 0.0 1.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PRP80069.1 - 4.2e-12 45.9 0.0 5.2e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PRP80069.1 - 2.2e-09 37.7 0.3 4.2e-09 36.8 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 PRP80069.1 - 3e-07 30.9 0.2 5.7e-07 30.0 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 PRP80069.1 - 1.5e-06 28.4 0.1 2.3e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 PRP80069.1 - 8e-05 22.3 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_Gly3P_dh_N PF01210.23 PRP80069.1 - 0.00053 20.0 0.1 0.65 10.0 0.8 3.2 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 PRP80069.1 - 0.0092 15.3 1.4 0.016 14.5 1.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PDH PF02153.17 PRP80069.1 - 0.065 12.2 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase 3HCDH_N PF02737.18 PRP80069.1 - 0.065 13.1 0.3 0.11 12.4 0.2 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 PRP80069.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA EF1G PF00647.19 PRP80070.1 - 2e-42 143.6 0.1 3.8e-42 142.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 PRP80070.1 - 5.1e-10 39.4 0.1 5.1e-10 39.4 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP80070.1 - 5.3e-06 26.4 0.3 1.6e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP80070.1 - 3.9e-05 23.8 0.1 0.00011 22.4 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP80070.1 - 0.00073 19.9 0.0 0.0037 17.6 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PRP80070.1 - 0.024 15.0 1.0 0.11 12.8 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 PRP80070.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Lactamase_B_2 PF12706.7 PRP80072.1 - 3.9e-07 29.8 0.3 1.3e-06 28.1 0.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP80072.1 - 7.8e-07 29.3 0.3 1.4e-06 28.4 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ABC2_membrane PF01061.24 PRP80073.1 - 1.3e-42 145.6 16.3 1.8e-42 145.1 16.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PRP80073.1 - 3.9e-25 89.0 0.1 9.2e-25 87.8 0.1 1.7 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PRP80073.1 - 2.1e-05 24.5 0.1 0.00011 22.2 0.2 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 PRP80073.1 - 0.00045 20.1 0.7 0.41 10.4 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PRP80073.1 - 0.0012 19.2 0.0 0.0026 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PRP80073.1 - 0.0013 19.1 0.1 0.0096 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 PRP80073.1 - 0.0035 16.5 12.0 0.0035 16.5 12.0 2.2 1 1 1 2 2 2 1 ABC-2 family transporter protein AAA PF00004.29 PRP80073.1 - 0.0094 16.4 0.1 0.056 13.9 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PRP80073.1 - 0.0097 16.2 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PRP80073.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PRP80073.1 - 0.015 15.8 0.1 0.032 14.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 PRP80073.1 - 0.016 15.1 0.2 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 PRP80073.1 - 0.016 14.9 0.3 0.041 13.6 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 PRP80073.1 - 0.021 13.9 0.2 0.037 13.1 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 PRP80073.1 - 0.022 15.1 0.0 0.067 13.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 PRP80073.1 - 0.03 14.4 0.1 0.068 13.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 PRP80073.1 - 0.032 14.1 0.3 0.085 12.8 0.1 1.7 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_25 PF13481.6 PRP80073.1 - 0.038 13.6 0.1 0.098 12.2 0.1 1.7 2 0 0 2 2 1 0 AAA domain Herpes_Helicase PF02689.14 PRP80073.1 - 0.043 11.7 0.0 0.062 11.2 0.0 1.1 1 0 0 1 1 1 0 Helicase ATPase_2 PF01637.18 PRP80073.1 - 0.055 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_30 PF13604.6 PRP80073.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PRP80073.1 - 0.063 13.2 0.1 0.18 11.7 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 PRP80073.1 - 0.074 13.5 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 PRP80073.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RuvB_N PF05496.12 PRP80073.1 - 0.098 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 PRP80073.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 PRP80073.1 - 0.11 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 PRP80073.1 - 0.16 11.3 0.2 0.7 9.3 0.2 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC2_membrane_2 PF12679.7 PRP80073.1 - 3.4 6.9 14.4 9.3 5.4 14.4 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Laminin_G_3 PF13385.6 PRP80074.1 - 2e-37 128.7 2.7 1.6e-19 70.6 0.1 2.9 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily DUF4982 PF16355.5 PRP80074.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Carb_bind PF10645.9 PRP80074.1 - 0.8 10.0 29.4 0.48 10.7 5.7 3.9 4 0 0 4 4 4 0 Carbohydrate binding Abhydrolase_1 PF00561.20 PRP80075.1 - 6.8e-23 81.6 0.0 8.6e-22 78.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP80075.1 - 1.9e-19 71.2 0.0 2.7e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP80075.1 - 3.4e-11 42.9 0.0 4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PRP80075.1 - 4.8e-06 26.5 0.1 0.0011 18.7 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 PRP80075.1 - 0.00014 22.1 0.0 0.00022 21.4 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 PRP80075.1 - 0.00031 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 PRP80075.1 - 0.0046 16.6 0.0 0.0086 15.7 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.14 PRP80075.1 - 0.0054 15.5 0.0 0.064 11.9 0.0 2.0 1 1 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 PRP80075.1 - 0.032 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Palm_thioest PF02089.15 PRP80075.1 - 0.032 14.1 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF915 PF06028.11 PRP80075.1 - 0.04 13.2 0.0 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 PRP80075.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 PRP80075.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region AAA PF00004.29 PRP80076.1 - 1.7e-37 128.8 0.0 5.7e-37 127.1 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP80076.1 - 5.8e-12 45.2 0.0 1.6e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 PRP80076.1 - 7.9e-09 35.4 0.0 2.2e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 PRP80076.1 - 8e-07 29.1 0.0 3.7e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PRP80076.1 - 7.6e-05 22.5 0.0 0.00027 20.7 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PRP80076.1 - 0.0009 19.7 0.5 0.0095 16.3 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PRP80076.1 - 0.0022 18.3 0.0 0.022 15.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 PRP80076.1 - 0.0022 18.1 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) CHASE2 PF05226.11 PRP80076.1 - 0.0089 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 CHASE2 domain TIP49 PF06068.13 PRP80076.1 - 0.0092 15.2 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 PRP80076.1 - 0.014 15.2 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MIT PF04212.18 PRP80076.1 - 0.016 15.3 0.1 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain AAA_25 PF13481.6 PRP80076.1 - 0.016 14.8 0.3 0.18 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 PRP80076.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 PRP80076.1 - 0.049 13.0 0.0 10 5.5 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 PRP80076.1 - 0.077 13.2 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PRP80076.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain MetOD2 PF18548.1 PRP80076.1 - 0.41 10.8 2.3 1.2 9.3 0.3 2.7 3 0 0 3 3 3 0 Metanogen output domain 2 EGF_2 PF07974.13 PRP80077.1 - 0.085 13.2 6.7 0.14 12.6 6.7 1.3 1 0 0 1 1 1 0 EGF-like domain PMT PF02366.18 PRP80079.1 - 0.0017 18.0 1.1 0.0027 17.3 1.1 1.2 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase SAM_2 PF07647.17 PRP80081.1 - 3.7e-16 59.0 0.1 6e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP80081.1 - 4.2e-14 52.7 0.0 5.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 PRP80081.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF2870 PF11069.8 PRP80082.1 - 4.2e-34 116.8 1.6 4.2e-34 116.8 1.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) Haemagg_act PF05860.13 PRP80082.1 - 0.11 12.4 0.0 0.47 10.3 0.0 2.1 2 1 0 2 2 2 0 haemagglutination activity domain TANGO2 PF05742.12 PRP80083.1 - 2.2e-68 231.1 0.0 2.7e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Sec1 PF00995.23 PRP80086.1 - 1.1e-99 335.2 0.0 1.3e-99 335.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GvpL_GvpF PF06386.11 PRP80087.1 - 0.31 10.9 3.5 0.52 10.2 3.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Spc24 PF08286.11 PRP80087.1 - 5.2 7.4 10.6 7.1 6.9 9.8 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Filament PF00038.21 PRP80088.1 - 0.11 12.0 0.2 0.11 12.0 0.2 1.0 1 0 0 1 1 1 0 Intermediate filament protein zf-C2H2_4 PF13894.6 PRP80089.1 - 0.99 10.4 5.2 0.34 11.9 1.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Vps52 PF04129.12 PRP80091.1 - 8.7e-93 311.8 21.9 1.4e-92 311.0 21.9 1.3 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 PRP80091.1 - 6.5e-06 24.8 7.7 6.5e-06 24.8 7.7 3.1 3 1 0 3 3 3 2 Exocyst complex component Sec3 Sec5 PF15469.6 PRP80091.1 - 0.0061 16.4 1.9 0.0061 16.4 1.9 3.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 Fes1 PF08609.10 PRP80091.1 - 0.95 10.4 8.8 0.25 12.3 1.6 3.8 5 0 0 5 5 5 0 Nucleotide exchange factor Fes1 Hox9_act PF04617.13 PRP80091.1 - 2 9.1 7.0 3.1 8.5 6.2 1.7 1 1 0 1 1 1 0 Hox9 activation region EF-hand_1 PF00036.32 PRP80092.1 - 8.6e-25 84.4 19.3 1.5e-06 27.3 0.5 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PRP80092.1 - 1.4e-22 77.7 10.3 7.6e-06 25.5 0.2 4.9 4 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 PRP80092.1 - 2.3e-22 79.2 8.7 2.5e-14 53.4 0.2 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PRP80092.1 - 5.5e-17 60.4 22.1 2.2e-06 26.9 0.3 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 PRP80092.1 - 1.9e-13 50.1 11.1 5.3e-07 29.4 2.4 4.0 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP80092.1 - 4.4e-08 33.4 0.5 0.031 14.6 0.3 3.1 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PRP80092.1 - 7.2e-05 22.7 5.5 0.038 13.9 0.3 3.5 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 PRP80092.1 - 0.00013 22.2 0.9 0.0059 16.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain p25-alpha PF05517.12 PRP80092.1 - 0.0042 17.2 0.8 0.018 15.2 0.2 2.2 1 1 1 2 2 2 1 p25-alpha OmpH PF03938.14 PRP80092.1 - 0.0045 17.3 4.5 0.0074 16.6 4.5 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) EF-hand_2 PF09068.11 PRP80092.1 - 0.0054 16.9 0.0 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 EF hand DUF4132 PF13569.6 PRP80092.1 - 0.028 14.2 0.2 0.054 13.3 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4132) EF-hand_14 PF17959.1 PRP80092.1 - 0.032 14.6 1.6 2.1 8.7 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain Dockerin_1 PF00404.18 PRP80092.1 - 0.044 14.0 0.3 4 7.7 0.0 2.7 3 0 0 3 3 3 0 Dockerin type I domain EAP30 PF04157.16 PRP80092.1 - 0.12 11.7 1.3 0.17 11.1 1.3 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family UPF0154 PF03672.13 PRP80092.1 - 0.15 12.1 4.0 0.45 10.6 2.3 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0154) FapA PF03961.13 PRP80092.1 - 0.19 10.3 1.1 0.27 9.8 0.2 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Caleosin PF05042.13 PRP80092.1 - 0.88 9.5 10.8 13 5.6 1.0 4.5 2 2 2 5 5 5 0 Caleosin related protein cNMP_binding PF00027.29 PRP80093.1 - 3.6e-31 107.1 0.1 5.2e-16 58.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF PF00617.19 PRP80093.1 - 1.8e-27 96.7 1.3 4e-27 95.5 0.2 2.2 3 0 0 3 3 3 1 RasGEF domain PLDc PF00614.22 PRP80093.1 - 2.5e-15 55.9 0.2 1.1e-09 38.1 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PRP80093.1 - 1.6e-12 47.4 0.0 2.7e-06 27.3 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain RasGEF_N PF00618.20 PRP80093.1 - 3.4e-11 43.3 0.0 1e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.29 PRP80093.1 - 0.00045 20.7 0.2 0.0021 18.5 0.1 2.2 2 0 0 2 2 2 1 PH domain Rubis-subs-bind PF09273.11 PRP80095.1 - 4.7e-17 62.9 0.3 8e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Glyco_trans_1_4 PF13692.6 PRP80096.1 - 7e-17 62.1 0.0 1.6e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PRP80096.1 - 1.2e-13 50.9 0.0 8.2e-13 48.2 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 HA PF03457.14 PRP80096.1 - 4.9e-08 33.2 9.4 0.001 19.3 0.0 4.5 4 1 0 4 4 4 2 Helicase associated domain Glyco_trans_1_2 PF13524.6 PRP80096.1 - 0.0013 19.0 0.0 0.0049 17.2 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sod_Fe_N PF00081.22 PRP80096.1 - 0.018 15.5 0.6 0.046 14.2 0.6 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Med9 PF07544.13 PRP80096.1 - 0.072 13.2 0.6 0.94 9.6 0.3 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Glyco_transf_4 PF13439.6 PRP80096.1 - 0.19 11.7 0.0 0.47 10.4 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Josephin PF02099.17 PRP80097.1 - 0.023 14.8 0.2 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Josephin Gemini_AL1 PF00799.20 PRP80097.1 - 0.029 14.7 0.5 0.27 11.6 0.9 2.2 3 0 0 3 3 3 0 Geminivirus Rep catalytic domain RGS PF00615.19 PRP80099.1 - 1.5e-23 83.3 0.2 5.1e-23 81.6 0.1 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain OB_NTP_bind PF07717.16 PRP80100.1 - 2.5e-26 91.8 0.0 5e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PRP80100.1 - 1.2e-24 86.7 0.0 1.2e-24 86.7 0.0 3.6 4 1 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PRP80100.1 - 3.6e-13 49.8 0.0 9.6e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 PRP80100.1 - 7.8e-11 42.2 0.6 2e-10 40.9 0.6 1.8 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 PRP80100.1 - 8.6e-08 32.1 0.2 1.9e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PRP80100.1 - 1.7e-07 31.6 0.1 4.5e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PRP80100.1 - 0.00061 19.6 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP80100.1 - 0.0023 18.3 0.1 0.0052 17.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 PRP80100.1 - 0.0035 17.3 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 PRP80100.1 - 0.0079 15.5 0.2 0.019 14.2 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 PRP80100.1 - 0.0087 16.6 2.8 0.75 10.3 0.1 3.4 2 1 1 3 3 3 1 ABC transporter Microtub_bd PF16796.5 PRP80100.1 - 0.0094 15.9 0.9 1.9 8.4 0.0 2.8 3 0 0 3 3 2 1 Microtubule binding T2SSE PF00437.20 PRP80100.1 - 0.014 14.5 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 PRP80100.1 - 0.022 14.8 0.2 0.15 12.1 0.2 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 PRP80100.1 - 0.072 12.5 0.5 0.26 10.7 0.2 2.0 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 PRP80100.1 - 0.075 12.8 0.0 17 5.1 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 PRP80100.1 - 7.4 7.0 0.0 7.4 7.0 0.0 4.3 5 0 0 5 5 5 0 AAA domain SMODS PF18144.1 PRP80101.1 - 0.041 14.0 0.0 0.05 13.8 0.0 1.1 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Phage_Integr_2 PF13009.6 PRP80102.1 - 0.21 10.7 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Putative phage integrase PepSY_TM PF03929.16 PRP80105.1 - 0.96 9.1 14.4 0.17 11.6 0.6 3.0 1 1 2 3 3 3 0 PepSY-associated TM region ABC_membrane PF00664.23 PRP80106.1 - 1.8e-36 126.2 10.6 2.6e-36 125.7 10.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PRP80106.1 - 4.3e-36 124.5 0.0 9.7e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PRP80106.1 - 2.5e-05 23.8 2.0 0.0015 18.0 0.6 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PRP80106.1 - 0.00019 21.3 1.0 0.00041 20.2 0.0 2.0 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 PRP80106.1 - 0.0012 18.8 0.1 0.0049 16.8 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 PRP80106.1 - 0.0021 17.8 1.5 0.0031 17.2 0.2 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP80106.1 - 0.0033 17.8 0.2 0.012 16.0 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 PRP80106.1 - 0.0042 16.9 0.0 0.0091 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 PRP80106.1 - 0.02 15.4 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 PRP80106.1 - 0.021 14.9 0.1 0.074 13.1 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain G-alpha PF00503.20 PRP80106.1 - 0.031 13.5 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 PRP80106.1 - 0.043 14.1 0.0 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PRP80106.1 - 0.068 13.2 0.0 2.1 8.4 0.0 2.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PRP80106.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 PRP80106.1 - 0.094 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 PRP80106.1 - 0.096 12.8 0.1 0.23 11.6 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4957 PF16318.5 PRP80106.1 - 0.1 12.5 0.2 0.34 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4957) AAA_23 PF13476.6 PRP80106.1 - 0.22 12.0 2.4 0.25 11.8 0.7 1.9 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.6 PRP80106.1 - 0.28 11.4 2.9 2.6 8.2 0.3 2.5 2 1 0 2 2 2 0 AAA domain Ank_2 PF12796.7 PRP80108.1 - 4.1e-22 78.6 0.3 3e-07 30.9 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80108.1 - 2.9e-17 62.8 4.1 0.00056 20.4 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP80108.1 - 1.2e-13 51.0 2.0 0.042 14.2 0.1 6.8 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80108.1 - 7.7e-08 32.0 1.7 9.5 7.2 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 PRP80108.1 - 9.1e-08 32.2 1.6 2.9 8.5 0.0 6.3 5 2 1 6 6 6 2 Ankyrin repeat PRODH PF18327.1 PRP80108.1 - 0.098 12.9 0.2 23 5.3 0.0 3.8 3 1 1 4 4 4 0 Proline utilization A proline dehydrogenase N-terminal domain Aa_trans PF01490.18 PRP80111.1 - 3.5e-14 52.3 28.6 7.8e-14 51.2 28.5 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Redoxin PF08534.10 PRP80112.1 - 1.7e-28 99.2 0.0 2.2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PRP80112.1 - 1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family HARE-HTH PF05066.13 PRP80113.1 - 2.2e-20 72.8 0.0 5.5e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain ASXH PF13919.6 PRP80113.1 - 2.5e-15 56.7 0.3 5.1e-15 55.7 0.3 1.6 1 0 0 1 1 1 1 Asx homology domain RPN13_C PF16550.5 PRP80113.1 - 5.6e-06 26.5 0.2 1.2e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 UCH-binding domain DUF3994 PF13159.6 PRP80113.1 - 0.015 15.8 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) efThoc1 PF11957.8 PRP80114.1 - 5.1e-31 107.9 20.6 8.1e-19 67.7 1.9 3.7 1 1 2 3 3 3 2 THO complex subunit 1 transcription elongation factor Nop14 PF04147.12 PRP80114.1 - 0.91 7.7 34.6 1.3 7.1 34.6 1.4 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.16 PRP80115.1 - 3.4e-13 49.2 42.0 1.3e-09 37.5 23.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 PRP80115.1 - 1.1e-12 47.9 7.7 1.1e-12 47.9 7.7 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Beta_helix PF13229.6 PRP80116.1 - 0.00075 19.4 12.8 0.00075 19.4 12.8 4.0 2 1 2 4 4 4 4 Right handed beta helix region v110 PF01639.17 PRP80116.1 - 0.15 12.0 6.4 0.52 10.2 6.3 2.0 1 1 0 1 1 1 0 Viral family 110 RNA_pol_Rpb2_6 PF00562.28 PRP80117.1 - 1.7e-114 382.9 0.0 4.7e-114 381.5 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PRP80117.1 - 3.4e-33 114.9 0.0 5.4e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 PRP80117.1 - 7.5e-28 96.5 0.0 1.5e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 PRP80117.1 - 1.1e-21 77.0 0.1 4.1e-21 75.2 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 PRP80117.1 - 2.5e-20 72.9 0.3 5.9e-20 71.7 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 PRP80117.1 - 4.1e-17 61.9 0.0 9.2e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_Me_trans PF04252.13 PRP80118.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase LysM PF01476.20 PRP80119.1 - 0.0026 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 LysM domain CHORD PF04968.12 PRP80119.1 - 0.0069 17.1 7.6 0.015 16.0 7.6 1.6 1 0 0 1 1 1 1 CHORD BTK PF00779.19 PRP80119.1 - 0.011 15.5 2.0 0.026 14.3 2.0 1.6 1 0 0 1 1 1 0 BTK motif UBA_4 PF14555.6 PRP80119.1 - 0.065 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain TAP_C PF03943.13 PRP80119.1 - 0.13 11.9 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 TAP C-terminal domain Ank_4 PF13637.6 PRP80120.1 - 7.5e-13 48.7 0.2 5.9e-07 29.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP80120.1 - 1.9e-09 37.6 0.0 9.1e-07 29.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP80120.1 - 4e-09 36.9 0.0 6.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PRP80120.1 - 9.7e-06 25.8 0.0 0.00013 22.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 PRP80120.1 - 1.9e-05 24.7 0.0 0.038 14.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat ABM PF03992.16 PRP80121.1 - 5.3e-20 71.3 0.5 5.5e-10 39.2 0.1 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 PRP80121.1 - 0.018 15.7 0.9 0.039 14.6 0.2 1.9 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain NIPSNAP PF07978.13 PRP80121.1 - 0.092 13.0 0.1 0.68 10.2 0.0 2.0 1 1 1 2 2 2 0 NIPSNAP Anoctamin PF04547.12 PRP80122.1 - 2.7e-15 56.2 12.8 7.8e-15 54.7 12.8 1.6 1 1 0 1 1 1 1 Calcium-activated chloride channel DUF1129 PF06570.11 PRP80122.1 - 0.0021 17.6 1.2 0.91 9.0 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1129) TMC PF07810.13 PRP80122.1 - 0.018 15.6 0.1 0.066 13.8 0.0 2.0 1 1 0 1 1 1 0 TMC domain SH3_9 PF14604.6 PRP80123.1 - 2.9e-09 36.6 0.1 8.1e-09 35.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 PRP80123.1 - 6.6e-08 32.0 0.1 1.6e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP80123.1 - 0.00068 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain F-box-like PF12937.7 PRP80123.1 - 0.025 14.5 0.2 0.091 12.7 0.0 1.9 2 0 0 2 2 2 0 F-box-like TPT PF03151.16 PRP80125.1 - 5.2e-32 111.4 30.0 6.2e-32 111.1 30.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PRP80125.1 - 5.8e-12 46.0 40.4 1.5e-09 38.2 11.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PRP80125.1 - 5.3e-06 25.9 30.3 6.5e-06 25.6 30.3 1.1 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 PRP80125.1 - 0.00062 19.0 19.7 0.025 13.8 19.7 2.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF4051 PF13260.6 PRP80125.1 - 5.8 6.7 5.5 0.86 9.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) WD40 PF00400.32 PRP80126.1 - 1e-24 86.3 21.6 0.0001 23.0 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80126.1 - 3.5e-23 81.7 5.5 8.5e-08 32.4 0.3 4.7 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP80126.1 - 3.1e-08 33.7 1.1 3.8e-05 23.7 0.1 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PRP80126.1 - 7.6e-08 31.7 2.1 0.0035 16.4 0.0 4.0 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP80126.1 - 0.001 17.8 0.9 0.002 16.8 0.1 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 PRP80126.1 - 0.11 11.5 2.2 1.5 7.7 0.2 2.7 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 PRP80126.1 - 0.18 11.1 0.0 15 4.8 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain MFS_1 PF07690.16 PRP80127.1 - 1.6e-42 145.7 28.1 1.6e-36 126.0 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP80127.1 - 5.4e-11 42.0 8.5 5.4e-11 42.0 8.5 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 PRP80127.1 - 0.00015 20.4 3.6 0.00026 19.5 3.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AvrM_N PF18247.1 PRP80128.1 - 0.18 11.8 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain Glyco_transf_10 PF00852.19 PRP80129.1 - 6.8e-32 110.6 0.0 2.6e-31 108.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term TnpV PF14198.6 PRP80129.1 - 0.046 13.7 0.9 0.17 11.8 0.9 2.0 1 0 0 1 1 1 0 Transposon-encoded protein TnpV PhoU PF01895.19 PRP80129.1 - 0.065 13.7 3.6 0.16 12.4 2.6 2.2 1 1 1 2 2 2 0 PhoU domain Baculo_PEP_C PF04513.12 PRP80129.1 - 4.4 7.4 18.9 1.3 9.1 3.6 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mac PF12464.8 PRP80130.1 - 1.4e-16 60.5 0.1 2.2e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 PRP80130.1 - 8.5e-15 53.8 14.3 5.7e-11 41.7 7.7 3.5 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PRP80130.1 - 4.9e-13 48.6 9.6 1.4e-09 37.6 6.2 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase 4HBT PF03061.22 PRP80131.1 - 4.3e-05 23.8 0.8 0.026 14.8 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Glucan_synthase PF02364.15 PRP80132.1 - 1.3e-80 271.7 13.1 1.4e-77 261.7 13.1 3.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase component Amidohydro_3 PF07969.11 PRP80134.1 - 4.4e-94 316.6 0.9 5.3e-94 316.3 0.9 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 PRP80134.1 - 7.5e-13 48.5 0.0 3.5e-10 39.7 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family Prefoldin_2 PF01920.20 PRP80135.1 - 0.00079 19.3 0.1 0.00085 19.3 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit PALP PF00291.25 PRP80137.1 - 3e-92 309.2 0.0 1.4e-79 267.5 0.0 2.5 2 1 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme PaaX_C PF08223.11 PRP80138.1 - 0.032 14.5 0.0 0.12 12.7 0.0 1.8 1 1 1 2 2 2 0 PaaX-like protein C-terminal domain DUF2968 PF11180.8 PRP80140.1 - 0.012 15.3 7.5 0.012 15.3 7.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) Cadherin_C PF01049.17 PRP80140.1 - 0.23 11.8 2.4 0.24 11.7 0.3 2.1 2 0 0 2 2 2 0 Cadherin cytoplasmic region Lge1 PF11488.8 PRP80140.1 - 0.33 11.2 12.8 0.034 14.3 5.0 3.1 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 KLRAQ PF10205.9 PRP80140.1 - 2.4 8.4 25.9 0.072 13.3 4.7 3.8 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein DUF3302 PF11742.8 PRP80141.1 - 5 7.3 14.9 12 6.1 0.0 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF3302) RRM_1 PF00076.22 PRP80142.1 - 6.8e-37 125.1 0.0 1.6e-19 69.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP80142.1 - 0.00036 20.6 0.0 0.7 10.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 PRP80142.1 - 0.0054 16.8 0.0 0.4 10.7 0.0 2.4 1 1 1 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 PRP80142.1 - 0.017 15.1 0.0 6.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 PRP80142.1 - 0.17 11.9 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain DPBB_1 PF03330.18 PRP80144.1 - 1.5e-08 34.8 2.3 1.5e-08 34.8 2.3 2.7 2 1 0 2 2 2 1 Lytic transglycolase DPBB_1 PF03330.18 PRP80145.1 - 2.8e-09 37.1 0.5 8.9e-09 35.5 0.5 1.9 1 1 0 1 1 1 1 Lytic transglycolase Colipase-like PF15083.6 PRP80145.1 - 3.3 7.9 10.8 2.3 8.4 1.7 2.3 2 0 0 2 2 2 0 Colipase-like RVT_1 PF00078.27 PRP80146.1 - 7.3e-06 25.7 0.0 1.8e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4817 PF16087.5 PRP80146.1 - 0.042 13.7 0.0 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) BBS2_Mid PF14783.6 PRP80148.1 - 0.0093 16.0 0.2 0.026 14.5 0.2 1.8 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region PolC_DP2 PF03833.13 PRP80148.1 - 0.012 13.5 0.2 0.016 13.1 0.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 UMP1 PF05348.11 PRP80149.1 - 4.3e-20 72.1 0.1 5e-20 71.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 UDP-g_GGTase PF06427.11 PRP80149.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.5 1 1 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase GTPase_binding PF09027.10 PRP80149.1 - 0.09 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 GTPase binding Epimerase PF01370.21 PRP80151.1 - 8.2e-12 45.1 1.3 2e-10 40.6 0.4 2.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP80151.1 - 1.5e-07 31.5 0.1 2.1e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PRP80151.1 - 7.6e-06 25.5 0.5 0.095 12.1 0.0 3.5 3 1 0 3 3 3 2 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 PRP80151.1 - 5.7e-05 23.4 0.1 0.00011 22.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 PRP80151.1 - 0.00042 20.8 0.1 0.0012 19.4 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 PRP80151.1 - 0.00045 19.8 1.8 0.00048 19.8 0.3 1.8 2 1 1 3 3 3 1 NmrA-like family RmlD_sub_bind PF04321.17 PRP80151.1 - 0.00077 18.6 0.1 0.0034 16.5 0.1 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 PRP80151.1 - 0.00077 18.6 0.2 0.54 9.2 0.0 2.6 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 PRP80151.1 - 0.0047 17.4 0.1 0.078 13.4 0.3 2.4 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 PRP80151.1 - 0.0057 16.6 1.2 0.019 14.8 1.1 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 PRP80151.1 - 0.0075 15.7 0.3 0.013 14.9 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.20 PRP80151.1 - 0.013 15.6 0.1 0.031 14.4 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.15 PRP80151.1 - 0.025 14.8 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4247 PF14042.6 PRP80152.1 - 0.11 13.2 0.1 0.2 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) Class_IIIsignal PF04021.12 PRP80152.1 - 0.87 9.6 4.0 1.6 8.8 4.0 1.5 1 0 0 1 1 1 0 Class III signal peptide Ras PF00071.22 PRP80154.1 - 3.6e-47 160.0 0.1 4.2e-47 159.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP80154.1 - 4.2e-32 110.9 0.4 6e-32 110.4 0.4 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP80154.1 - 6e-12 45.4 0.1 7.9e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 PRP80154.1 - 3.7e-06 26.3 0.0 0.043 13.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PRP80154.1 - 9.2e-06 25.7 0.1 1.4e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP80154.1 - 1.1e-05 25.0 0.1 1.7e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP80154.1 - 4.1e-05 23.0 0.0 5.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 PRP80154.1 - 0.00011 22.1 0.6 0.13 12.1 0.1 2.3 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 PRP80154.1 - 0.00057 19.4 0.0 0.0016 18.0 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 PRP80154.1 - 0.0027 17.6 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PRP80154.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 PRP80154.1 - 0.023 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRPRB PF09439.10 PRP80154.1 - 0.033 13.6 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PRP80154.1 - 0.035 13.8 0.0 0.98 9.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_32 PF13654.6 PRP80154.1 - 0.037 12.8 0.1 0.074 11.8 0.1 1.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PRP80154.1 - 0.089 13.2 0.1 0.62 10.5 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 PRP80154.1 - 0.09 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 PRP80154.1 - 0.098 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GST_C PF00043.25 PRP80155.1 - 6.8e-07 29.4 0.1 1.8e-06 28.1 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP80155.1 - 3.6e-06 27.3 0.0 1.3e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP80155.1 - 5.7e-06 26.5 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP80155.1 - 5.8e-06 26.6 0.1 1.8e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP80155.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 PRP80156.1 - 7.9e-11 42.3 7.8 0.0098 16.7 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80156.1 - 4.9e-07 30.0 0.0 0.037 14.3 0.0 3.7 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PAPA-1 PF04795.12 PRP80156.1 - 5.2 7.9 16.5 1 10.2 7.7 2.7 2 0 0 2 2 2 0 PAPA-1-like conserved region Na_Ca_ex PF01699.24 PRP80157.1 - 1.6e-13 50.9 35.4 1.1e-09 38.4 8.0 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Otopetrin PF03189.13 PRP80157.1 - 0.017 13.9 1.8 0.03 13.2 1.8 1.3 1 0 0 1 1 1 0 Otopetrin p450 PF00067.22 PRP80158.1 - 9.8e-07 27.9 1.3 5.4e-06 25.4 1.3 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 PRP80159.1 - 0.025 13.3 0.0 0.027 13.2 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 JmjC PF02373.22 PRP80161.1 - 2e-10 41.1 0.0 1.4e-08 35.2 0.0 3.2 3 0 0 3 3 3 1 JmjC domain, hydroxylase LpqV PF17301.2 PRP80161.1 - 0.00037 20.7 0.3 0.0024 18.1 0.0 2.3 2 0 0 2 2 2 1 Putative lipoprotein LpqV GFA PF04828.14 PRP80161.1 - 0.022 15.1 0.9 11 6.4 0.3 2.8 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Peptidase_C48 PF02902.19 PRP80162.1 - 0.0014 18.5 10.0 0.0016 18.3 0.3 2.7 2 1 1 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 PRP80162.1 - 0.0043 16.7 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Legionella ubiquitin-specific protease A domain BPL_N PF09825.9 PRP80162.1 - 0.005 16.0 0.1 0.0088 15.2 0.1 1.4 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal RIF5_SNase_1 PF18187.1 PRP80162.1 - 0.051 13.3 0.4 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 TIG PF01833.24 PRP80163.1 - 9.4e-42 141.0 49.6 8.6e-12 45.0 0.5 9.1 7 1 1 8 8 8 8 IPT/TIG domain DUF4333 PF14230.6 PRP80163.1 - 1.7 9.0 7.7 4.8 7.5 0.1 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4333) MACPF PF01823.19 PRP80164.1 - 1.8e-22 80.5 2.2 4.4e-22 79.2 2.2 1.7 1 0 0 1 1 1 1 MAC/Perforin domain PAN_1 PF00024.26 PRP80164.1 - 3.5e-06 26.9 2.3 1.1e-05 25.3 2.3 1.8 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 PRP80164.1 - 1.3e-05 25.0 3.6 4.5e-05 23.3 3.6 2.0 1 0 0 1 1 1 1 PAN domain AAA_6 PF12774.7 PRP80165.1 - 5e-09 35.6 0.2 3.5e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_6 PF12774.7 PRP80167.1 - 1.8e-13 50.2 0.1 1.8e-13 50.1 0.1 1.0 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region CTD PF12815.7 PRP80169.1 - 0.0048 17.4 0.0 0.0088 16.6 0.0 1.5 1 1 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 GTP_EFTU PF00009.27 PRP80170.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Gemini_V2 PF01524.17 PRP80173.1 - 0.042 14.0 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 Geminivirus V2 protein MACPF PF01823.19 PRP80174.1 - 4.4e-22 79.2 0.1 9.2e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 MAC/Perforin domain PAN_1 PF00024.26 PRP80174.1 - 6.4e-07 29.2 7.5 0.004 17.1 6.0 2.8 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 PRP80174.1 - 2.8e-06 27.1 10.5 0.00021 21.1 2.6 2.9 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PRP80174.1 - 0.34 11.1 10.4 0.03 14.4 2.9 2.8 2 0 0 2 2 2 0 PAN-like domain PAN_3 PF08277.12 PRP80174.1 - 1.3 8.9 12.5 1.4 8.8 0.6 3.2 2 0 0 2 2 2 0 PAN-like domain Ank_2 PF12796.7 PRP80175.1 - 1.3e-14 54.5 0.0 8.2e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80175.1 - 2.6e-09 37.4 2.3 0.00017 22.1 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP80175.1 - 5.3e-06 26.6 0.2 0.64 10.4 0.0 4.4 3 2 2 5 5 5 2 Ankyrin repeats (many copies) F-box PF00646.33 PRP80175.1 - 0.00026 20.8 0.3 0.00076 19.3 0.3 1.8 1 0 0 1 1 1 1 F-box domain Ank_3 PF13606.6 PRP80175.1 - 0.00034 20.8 0.2 17 6.4 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat F-box-like PF12937.7 PRP80175.1 - 0.011 15.7 0.3 0.024 14.5 0.3 1.6 1 0 0 1 1 1 0 F-box-like Ank PF00023.30 PRP80175.1 - 0.58 10.7 4.7 62 4.3 0.0 4.9 6 1 1 7 7 7 0 Ankyrin repeat WRNPLPNID PF15017.6 PRP80175.1 - 1.4 9.9 5.9 3.2 8.7 5.9 1.6 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF3348 PF11828.8 PRP80176.1 - 0.0091 15.7 0.1 0.013 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3348) DNase_II PF03265.15 PRP80178.1 - 1e-14 54.6 0.2 2.1e-14 53.5 0.2 1.5 1 0 0 1 1 1 1 Deoxyribonuclease II Zincin_1 PF06262.11 PRP80178.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase Fer4_22 PF17179.4 PRP80180.1 - 0.18 12.7 0.7 22 6.0 0.1 2.8 2 0 0 2 2 2 0 4Fe-4S dicluster domain DUF3586 PF12131.8 PRP80181.1 - 2.7 8.3 13.7 0.14 12.3 3.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3586) CadC_C1 PF18500.1 PRP80182.1 - 0.00051 20.2 1.6 12 6.0 0.0 4.1 3 1 0 3 3 3 3 CadC C-terminal domain 1 NHS PF15273.6 PRP80182.1 - 0.018 14.2 0.1 0.82 8.7 0.0 2.1 2 0 0 2 2 2 0 NHS-like Moricin PF06451.11 PRP80182.1 - 0.04 13.7 0.4 47 3.9 0.0 3.4 3 0 0 3 3 3 0 Moricin zf-RING_7 PF02591.15 PRP80182.1 - 0.26 11.5 4.3 27 5.0 0.1 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain Acyl-CoA_dh_1 PF00441.24 PRP80184.1 - 2.2e-29 102.6 2.9 3.3e-29 102.0 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PRP80184.1 - 1.2e-13 51.7 0.2 2.2e-12 47.6 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PRP80184.1 - 4.6e-10 39.6 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SH2 PF00017.24 PRP80185.1 - 9.1e-14 51.3 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 SH2 domain DUF599 PF04654.12 PRP80185.1 - 0.09 12.2 0.8 0.15 11.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 SH2_2 PF14633.6 PRP80185.1 - 0.19 11.1 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Ank_4 PF13637.6 PRP80186.1 - 9.2e-13 48.4 0.1 3.2e-07 30.7 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP80186.1 - 2.4e-11 44.0 0.0 4.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP80186.1 - 2.8e-11 43.4 1.3 2.7e-07 30.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80186.1 - 2.6e-10 39.6 0.0 1.8e-05 24.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PRP80186.1 - 6.8e-10 38.9 0.1 3.6e-07 30.3 0.2 3.3 3 0 0 3 3 3 1 Ankyrin repeat CENP-F_leu_zip PF10473.9 PRP80188.1 - 0.016 15.2 0.2 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macro PF01661.21 PRP80189.1 - 9.7e-36 122.4 0.1 2.1e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 Macro domain ADP_ribosyl_GH PF03747.14 PRP80191.1 - 1.6e-24 87.1 0.0 3.4e-24 86.1 0.0 1.5 1 1 1 2 2 2 1 ADP-ribosylglycohydrolase zf-MYND PF01753.18 PRP80192.1 - 9.3e-09 35.2 9.8 1.5e-08 34.5 9.8 1.4 1 0 0 1 1 1 1 MYND finger CH PF00307.31 PRP80193.1 - 1.7e-15 57.2 0.2 1.7e-11 44.2 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF4735 PF15882.5 PRP80193.1 - 1.1 8.7 12.0 0.46 9.9 5.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4735) DUF3135 PF11333.8 PRP80193.1 - 6.2 7.1 8.0 11 6.4 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) DUF2947 PF11163.8 PRP80193.1 - 8.4 6.2 8.1 1.4 8.7 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2947) ASH PF15780.5 PRP80194.1 - 9.6e-14 51.4 2.2 0.56 10.5 0.0 7.8 6 1 1 7 7 7 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PRP80194.1 - 6.1e-07 29.5 0.0 4.3 7.6 0.0 5.3 4 0 0 4 4 4 2 Flagellar-associated PapD-like TMEM131_like PF12371.8 PRP80194.1 - 0.00015 21.9 0.1 1.4 9.3 0.0 5.9 6 1 0 6 6 6 1 Transmembrane protein 131-like Glyco_transf_36 PF06165.11 PRP80194.1 - 0.79 9.1 3.2 16 4.8 0.0 3.6 3 1 0 3 3 3 0 Glycosyltransferase family 36 Pkinase_Tyr PF07714.17 PRP80195.1 - 7.5e-24 84.4 0.1 1.1e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP80195.1 - 1.3e-19 69.7 49.0 4.7e-07 29.5 3.1 8.0 4 2 2 8 8 8 7 Leucine rich repeat Pkinase PF00069.25 PRP80195.1 - 9.5e-17 61.2 0.0 1.6e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP80195.1 - 5.1e-15 55.4 61.9 3.8e-05 24.0 1.5 10.4 5 2 4 11 11 11 6 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP80195.1 - 4.8e-08 33.4 0.6 1.8e-07 31.5 0.6 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP80195.1 - 4.4e-05 23.5 44.6 2.1 9.2 0.0 12.8 12 2 1 13 13 13 2 Leucine Rich Repeat EphA2_TM PF14575.6 PRP80195.1 - 0.064 14.1 0.1 0.15 12.9 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_6 PF13516.6 PRP80195.1 - 0.094 12.8 32.8 3.8 7.8 0.5 10.1 11 0 0 11 11 11 0 Leucine Rich repeat DUF2353 PF09789.9 PRP80196.1 - 0.016 14.6 29.9 0.015 14.7 28.9 1.4 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) NPV_P10 PF05531.12 PRP80196.1 - 0.96 10.0 4.0 5.3 7.6 0.3 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PRP80196.1 - 2.2 8.3 12.7 3.1 7.8 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 PRP80196.1 - 2.5 8.5 30.6 0.16 12.4 11.7 2.2 1 1 1 2 2 2 0 Fez1 Glyco_hydro_72 PF03198.14 PRP80197.1 - 4.8e-88 295.4 0.5 7.8e-88 294.7 0.5 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 PRP80197.1 - 4.9e-18 65.6 7.6 4.9e-18 65.6 7.6 2.8 3 0 0 3 3 3 1 X8 domain OS-D PF03392.13 PRP80197.1 - 0.087 12.9 0.8 0.27 11.4 0.5 2.0 1 1 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D WD40 PF00400.32 PRP80198.1 - 4.2e-25 87.5 9.7 2e-05 25.3 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 PRP80198.1 - 2.7e-09 36.3 0.4 0.0067 15.1 0.1 4.4 2 2 0 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PRP80198.1 - 2.8e-06 27.5 0.9 3 8.2 0.0 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SH2 PF00017.24 PRP80198.1 - 3.2e-06 27.1 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 SH2 domain PQQ_3 PF13570.6 PRP80198.1 - 6.4e-06 26.5 0.0 2 9.0 0.0 4.5 4 0 0 4 4 4 1 PQQ-like domain WD40_like PF17005.5 PRP80198.1 - 0.0018 17.6 1.6 0.066 12.5 0.1 3.1 1 1 3 4 4 4 1 WD40-like domain PQQ_2 PF13360.6 PRP80198.1 - 0.002 17.8 0.0 0.28 10.7 0.0 2.7 1 1 2 3 3 3 2 PQQ-like domain RabGAP-TBC PF00566.18 PRP80199.1 - 1.6e-50 171.7 4.8 2.4e-50 171.2 2.3 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 PRP80199.1 - 1.4e-08 34.6 0.3 0.00045 20.1 0.1 3.2 2 1 0 2 2 2 2 GRAM domain RGS PF00615.19 PRP80199.1 - 1.7e-05 25.1 0.0 0.00011 22.4 0.0 2.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF3857 PF12969.7 PRP80199.1 - 0.057 13.5 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Myb_DNA-binding PF00249.31 PRP80199.1 - 0.1 12.8 0.0 0.34 11.1 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ras PF00071.22 PRP80200.1 - 7.9e-61 204.4 0.4 1.2e-60 203.8 0.4 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP80200.1 - 4.9e-35 120.4 0.1 9.3e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP80200.1 - 1.7e-14 53.7 0.1 2.5e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP80200.1 - 6.3e-07 29.5 0.1 1.3e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP80200.1 - 4.1e-05 23.2 0.1 0.00013 21.6 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP80200.1 - 5.2e-05 23.2 3.2 0.011 15.6 0.0 2.5 3 0 0 3 3 2 2 RsgA GTPase Gtr1_RagA PF04670.12 PRP80200.1 - 0.00036 20.0 0.1 0.00052 19.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PRP80200.1 - 0.0014 19.1 0.0 0.0048 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.9 PRP80200.1 - 0.0034 17.1 0.0 0.0085 15.8 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PRP80200.1 - 0.0064 16.8 0.0 0.048 13.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 PRP80200.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 PRP80200.1 - 0.028 14.2 0.0 0.052 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PRP80200.1 - 0.046 14.2 0.1 0.092 13.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 PRP80200.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein NTPase_1 PF03266.15 PRP80200.1 - 0.06 13.2 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 NTPase DUF2868 PF11067.8 PRP80200.1 - 0.1 12.1 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) AAA_21 PF13304.6 PRP80200.1 - 0.1 12.4 1.3 0.33 10.7 1.3 2.1 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 PRP80200.1 - 0.12 11.8 0.2 0.43 10.1 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MCM PF00493.23 PRP80200.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain SH2 PF00017.24 PRP80202.1 - 1.8e-14 53.6 0.0 8.7e-07 29.0 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP80202.1 - 3.5e-06 27.6 0.1 7.5e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 PF02762.14 PRP80202.1 - 0.0033 17.3 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain Yippee-Mis18 PF03226.14 PRP80203.1 - 6.4e-19 68.1 0.2 1.2e-18 67.2 0.2 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HBM PF16591.5 PRP80203.1 - 0.0078 15.7 0.4 0.012 15.1 0.4 1.2 1 0 0 1 1 1 1 Helical bimodular sensor domain DUF1732 PF08340.11 PRP80203.1 - 0.089 12.8 1.1 0.36 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) MFS_2 PF13347.6 PRP80204.1 - 1.8e-11 43.3 10.8 1.8e-11 43.3 10.8 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.16 PRP80204.1 - 3.3e-11 42.7 32.7 3.3e-11 42.7 32.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Lipase_3 PF01764.25 PRP80205.1 - 4.2e-25 88.3 0.0 8.8e-25 87.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) VWA PF00092.28 PRP80205.1 - 7.4e-12 45.9 0.0 2e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP80205.1 - 1.3e-06 29.0 0.0 3.9e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Hydrolase_4 PF12146.8 PRP80205.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 PRP80205.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Atrophin-1 PF03154.15 PRP80205.1 - 5.9 5.0 8.7 9.7 4.3 8.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family AAA PF00004.29 PRP80207.1 - 2.4e-40 138.0 0.0 5.2e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PRP80207.1 - 3e-17 62.3 0.1 6e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PRP80207.1 - 5.4e-13 48.5 1.2 4.8e-12 45.5 0.1 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 PRP80207.1 - 2.5e-06 28.0 0.7 0.00068 20.1 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PRP80207.1 - 1.4e-05 25.1 0.1 7.1e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PRP80207.1 - 3.1e-05 24.2 0.0 0.00037 20.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 PRP80207.1 - 0.00025 20.8 0.0 0.00069 19.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PRP80207.1 - 0.00029 21.1 1.8 0.03 14.6 0.1 2.9 2 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 PRP80207.1 - 0.0024 17.1 0.0 0.0059 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 PRP80207.1 - 0.0068 15.9 0.0 0.035 13.6 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 PRP80207.1 - 0.0088 15.4 0.1 0.041 13.3 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PRP80207.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PRP80207.1 - 0.012 15.4 0.2 0.12 12.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PRP80207.1 - 0.018 14.9 0.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PRP80207.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 PRP80207.1 - 0.021 14.0 0.5 0.51 9.5 0.0 2.3 1 1 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 PRP80207.1 - 0.04 14.5 0.1 0.15 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PRP80207.1 - 0.045 14.2 0.0 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 PRP80207.1 - 0.054 12.8 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 KaiC ZapB PF06005.12 PRP80207.1 - 0.058 13.8 1.7 0.1 13.1 0.6 2.0 2 0 0 2 2 1 0 Cell division protein ZapB Sigma54_activat PF00158.26 PRP80207.1 - 0.063 13.0 0.0 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 PRP80207.1 - 0.069 12.7 0.0 0.18 11.3 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 PRP80207.1 - 0.086 12.4 1.0 0.44 10.1 0.1 2.2 1 1 0 2 2 2 0 AAA domain CPT PF07931.12 PRP80207.1 - 0.093 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 PRP80207.1 - 0.11 11.6 0.1 0.76 8.8 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 PRP80207.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Pkinase_Tyr PF07714.17 PRP80208.1 - 1.2e-54 185.3 0.0 2.5e-54 184.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80208.1 - 6.1e-48 163.5 0.0 1.7e-47 162.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.24 PRP80208.1 - 1.1e-05 25.5 0.0 2.9e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain THRAP3_BCLAF1 PF15440.6 PRP80208.1 - 0.0065 15.5 35.6 0.008 15.2 35.6 1.1 1 0 0 1 1 1 1 THRAP3/BCLAF1 family Cbl_N2 PF02761.14 PRP80208.1 - 0.071 13.8 0.1 0.21 12.3 0.1 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain Hamartin PF04388.12 PRP80208.1 - 0.18 10.4 33.2 0.26 9.9 33.2 1.2 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 PRP80208.1 - 9.6 4.6 48.8 40 2.6 48.9 1.7 1 1 0 1 1 1 0 Macoilin family DUF3712 PF12505.8 PRP80209.1 - 1.5e-34 119.0 15.7 2.1e-15 57.1 1.3 4.0 3 0 0 3 3 3 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 PRP80209.1 - 3.2 8.3 9.5 20 5.8 0.0 5.8 8 0 0 8 8 8 0 Late embryogenesis abundant protein p450 PF00067.22 PRP80210.1 - 5.1e-138 460.7 0.1 7.2e-68 229.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_1 PF00667.20 PRP80210.1 - 1.2e-90 303.0 0.0 1.2e-28 100.2 0.0 3.5 3 0 0 3 3 3 3 FAD binding domain NAD_binding_1 PF00175.21 PRP80210.1 - 1.2e-42 145.0 0.9 5.9e-14 52.6 0.1 3.9 3 0 0 3 3 3 3 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 PRP80210.1 - 3.7e-37 127.7 4.3 4.2e-18 65.9 0.0 3.6 4 0 0 4 4 4 2 Flavodoxin Poly_export PF02563.16 PRP80210.1 - 0.0003 21.0 0.0 19 5.6 0.0 3.8 3 0 0 3 3 3 0 Polysaccharide biosynthesis/export protein TetR_C_5 PF08360.11 PRP80210.1 - 0.00047 20.3 0.1 13 6.0 0.0 3.9 3 0 0 3 3 3 0 QacR-like protein, C-terminal region DUF806 PF05657.11 PRP80210.1 - 0.003 18.0 0.2 3.1 8.3 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF806) Prenyltransf PF01255.19 PRP80210.1 - 0.01 15.4 2.0 0.79 9.2 0.1 2.6 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Eco57I PF07669.11 PRP80210.1 - 0.013 16.0 0.4 5.6 7.5 0.0 3.1 2 0 0 2 2 2 0 Eco57I restriction-modification methylase SAC3_GANP PF03399.16 PRP80210.1 - 0.023 14.1 0.0 4 6.7 0.0 3.5 4 0 0 4 4 4 0 SAC3/GANP family Flavodoxin_5 PF12724.7 PRP80210.1 - 0.034 14.4 0.4 17 5.6 0.0 3.2 3 0 0 3 3 3 0 Flavodoxin domain PAS PF00989.25 PRP80210.1 - 0.059 13.4 1.4 97 3.0 0.0 4.0 3 0 0 3 3 3 0 PAS fold Z1 PF10593.9 PRP80210.1 - 0.094 12.2 0.0 10 5.6 0.0 3.0 2 0 0 2 2 2 0 Z1 domain TPR_7 PF13176.6 PRP80210.1 - 0.099 12.7 2.1 74 3.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MRP-S24 PF14955.6 PRP80210.1 - 0.11 12.5 0.4 19 5.2 0.0 3.2 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S24 FMN_red PF03358.15 PRP80210.1 - 0.16 11.7 0.0 17 5.1 0.0 2.7 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Pap_E4 PF02711.14 PRP80211.1 - 0.18 12.7 2.6 0.24 12.4 2.6 1.2 1 0 0 1 1 1 0 E4 protein ABC_membrane PF00664.23 PRP80213.1 - 5.2e-38 131.3 9.8 6.6e-38 130.9 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PRP80213.1 - 1.7e-35 122.5 0.0 4.2e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PRP80213.1 - 1.8e-05 24.3 1.0 0.00022 20.7 1.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 PRP80213.1 - 0.00095 19.6 0.1 1.5 9.2 0.2 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP80213.1 - 0.0033 17.7 0.4 0.038 14.3 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PRP80213.1 - 0.0045 17.0 0.0 1.1 9.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP80213.1 - 0.0078 16.6 0.1 0.021 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 PRP80213.1 - 0.0081 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PRP80213.1 - 0.013 15.7 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Calici_coat_C PF08435.11 PRP80213.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal DUF4140 PF13600.6 PRP80213.1 - 0.074 13.5 0.1 0.56 10.7 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_29 PF13555.6 PRP80213.1 - 0.086 12.6 2.0 0.097 12.4 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain APS_kinase PF01583.20 PRP80213.1 - 0.09 12.7 0.1 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF4446 PF14584.6 PRP80213.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ABC_membrane_3 PF13748.6 PRP80213.1 - 0.16 11.2 9.5 0.69 9.1 9.5 1.9 1 1 0 1 1 1 0 ABC transporter transmembrane region DUF5353 PF17304.2 PRP80213.1 - 0.3 10.9 2.6 0.69 9.7 2.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Pkinase_Tyr PF07714.17 PRP80214.1 - 1.3e-72 244.3 0.0 1.9e-72 243.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80214.1 - 1.5e-52 178.6 0.0 2.1e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP80214.1 - 7.6e-07 28.7 0.0 0.00016 21.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP80214.1 - 0.0006 19.2 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP80214.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1137 PF06587.11 PRP80214.1 - 0.016 15.3 0.9 0.17 12.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1137) DUF4957 PF16318.5 PRP80214.1 - 0.19 11.7 50.2 0.12 12.3 0.7 9.3 7 3 1 8 8 8 0 Domain of unknown function (DUF4957) SGL PF08450.12 PRP80215.1 - 1.6e-77 260.4 0.0 1.9e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 PRP80215.1 - 0.0007 19.5 0.0 1.9 9.0 0.1 3.1 2 0 0 2 2 2 2 Two component regulator propeller WW PF00397.26 PRP80215.1 - 0.017 15.2 0.3 0.96 9.6 0.3 2.7 2 0 0 2 2 2 0 WW domain DUF839 PF05787.13 PRP80215.1 - 0.089 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) DOT1 PF08123.13 PRP80216.1 - 5.4e-24 84.9 0.0 1e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 PRP80216.1 - 0.054 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase DEAD PF00270.29 PRP80217.1 - 4.1e-21 75.5 0.0 2.7e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP80217.1 - 5.5e-21 75.0 0.0 6.3e-17 61.9 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PRP80217.1 - 1.3e-09 38.6 5.6 1.3e-09 38.6 5.6 2.5 3 1 1 4 4 4 1 RecQ zinc-binding ResIII PF04851.15 PRP80217.1 - 2.1e-07 31.1 0.0 5.1e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PRP80217.1 - 0.0021 18.3 2.6 0.03 14.6 0.1 3.1 3 1 1 4 4 4 1 AAA domain UPF0175 PF03683.13 PRP80217.1 - 0.13 12.0 0.1 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) TIG PF01833.24 PRP80218.1 - 0 1532.3 1429.3 1.1e-10 41.5 4.5 105.2 103 2 2 105 105 105 103 IPT/TIG domain SspH PF08141.12 PRP80218.1 - 1.3e-10 41.2 4.1 18 5.6 0.0 9.9 10 0 0 10 10 10 5 Small acid-soluble spore protein H family Borealin PF10512.9 PRP80218.1 - 7.8 6.5 17.0 0.56 10.2 0.1 7.6 6 0 0 6 6 6 0 Cell division cycle-associated protein 8 Pkinase PF00069.25 PRP80220.1 - 1.9e-54 184.8 0.0 5.6e-54 183.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80220.1 - 5.9e-27 94.6 0.0 2e-20 73.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase cNMP_binding PF00027.29 PRP80220.1 - 5.4e-23 80.9 0.1 1.3e-10 41.2 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GRAM PF02893.20 PRP80220.1 - 3.4e-08 33.3 0.9 8.3e-08 32.1 0.9 1.6 1 0 0 1 1 1 1 GRAM domain APH PF01636.23 PRP80220.1 - 0.0014 18.6 0.7 0.011 15.7 0.7 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family YfkD PF14167.6 PRP80220.1 - 0.018 14.2 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 YfkD-like protein Kdo PF06293.14 PRP80220.1 - 0.029 13.7 0.0 0.079 12.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP80220.1 - 0.03 13.3 0.1 0.076 12.0 0.1 1.7 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 PRP80220.1 - 0.037 13.4 1.1 0.056 12.8 0.1 1.8 2 0 0 2 2 2 0 Kinase-like Peptidase_M48 PF01435.18 PRP80221.1 - 3.4e-20 72.7 0.3 1.3e-18 67.4 0.3 2.2 1 1 0 1 1 1 1 Peptidase family M48 GSDH PF07995.11 PRP80222.1 - 2.2e-32 112.7 0.0 3.6e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Folate_rec PF03024.14 PRP80222.1 - 8.6e-09 35.5 7.5 1.5e-08 34.7 7.5 1.3 1 0 0 1 1 1 1 Folate receptor family Toxin_7 PF05980.12 PRP80222.1 - 0.046 14.0 0.6 0.15 12.3 0.6 1.9 1 0 0 1 1 1 0 Toxin 7 PQQ_3 PF13570.6 PRP80222.1 - 0.77 10.3 7.2 21 5.7 0.1 4.0 4 0 0 4 4 4 0 PQQ-like domain RabGAP-TBC PF00566.18 PRP80223.1 - 3.2e-46 157.7 2.6 8.1e-46 156.4 0.6 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PH PF00169.29 PRP80223.1 - 2.1e-05 25.0 0.0 4.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 PRP80223.1 - 0.046 14.1 0.4 0.73 10.2 0.4 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain EI24 PF07264.11 PRP80224.1 - 1.4e-06 28.7 5.0 2.5e-06 27.9 5.0 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) PP2C PF00481.21 PRP80226.1 - 1.1e-57 195.6 0.0 2e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PRP80226.1 - 7.9e-06 25.7 0.1 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C EF-hand_7 PF13499.6 PRP80226.1 - 0.00045 20.6 3.2 0.0012 19.2 3.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair SpoIIE PF07228.12 PRP80226.1 - 0.007 16.3 0.2 0.92 9.4 0.0 2.4 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) EF-hand_4 PF12763.7 PRP80226.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand CpcD PF01383.21 PRP80226.1 - 0.12 12.6 0.0 0.54 10.6 0.0 2.1 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain EF-hand_6 PF13405.6 PRP80226.1 - 0.2 11.7 3.9 4.1 7.6 3.6 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 PRP80226.1 - 0.64 9.7 3.6 22 4.9 3.8 2.5 2 0 0 2 2 2 0 EF hand zf-C2H2 PF00096.26 PRP80227.1 - 2.1e-11 43.6 11.1 2.4e-06 27.7 3.1 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP80227.1 - 2.6e-08 34.0 9.0 0.00011 22.7 2.0 3.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PRP80227.1 - 4.3e-08 33.2 16.9 3e-05 24.2 1.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 PRP80227.1 - 1.3e-05 25.3 4.2 0.052 13.9 0.2 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP80227.1 - 7.8e-05 22.9 4.2 0.15 12.5 0.4 3.2 2 1 1 3 3 3 2 Zinc-finger of C2H2 type LisH PF08513.11 PRP80227.1 - 0.0033 17.3 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 LisH zf-H2C2_5 PF13909.6 PRP80227.1 - 0.0068 16.1 1.9 0.0068 16.1 1.9 3.1 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2HE PF16278.5 PRP80227.1 - 0.028 14.9 10.7 0.075 13.5 2.6 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger FYDLN_acid PF09538.10 PRP80227.1 - 0.22 12.2 5.7 6.8 7.4 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-C2H2_6 PF13912.6 PRP80227.1 - 1 9.4 6.2 4.7 7.3 0.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Alpha_kinase PF02816.18 PRP80234.1 - 3.8e-42 144.5 0.2 3.8e-42 144.5 0.2 2.0 2 0 0 2 2 2 1 Alpha-kinase family Neur_chan_memb PF02932.16 PRP80234.1 - 3.8 7.5 23.7 7.2 6.6 23.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VWA_2 PF13519.6 PRP80235.1 - 0.013 16.1 0.0 0.054 14.1 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain Golgin_A5 PF09787.9 PRP80235.1 - 0.27 10.7 7.5 0.44 9.9 7.5 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 AIP3 PF03915.13 PRP80235.1 - 0.52 9.3 6.4 0.8 8.7 6.4 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 SOGA PF11365.8 PRP80235.1 - 4.3 8.5 8.8 6.9 7.9 4.1 2.7 1 1 2 3 3 3 0 Protein SOGA HPP PF04982.13 PRP80236.1 - 4.6e-28 97.8 9.1 6.7e-28 97.3 9.1 1.2 1 0 0 1 1 1 1 HPP family RPOL_N PF14700.6 PRP80236.1 - 0.018 14.4 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF1770 PF08589.10 PRP80236.1 - 0.13 13.2 1.4 0.2 12.6 1.4 1.2 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) PHO4 PF01384.20 PRP80236.1 - 0.28 10.2 6.6 0.38 9.7 6.6 1.2 1 0 0 1 1 1 0 Phosphate transporter family Connexin PF00029.19 PRP80236.1 - 0.66 9.7 2.0 0.99 9.1 2.0 1.2 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 PRP80236.1 - 0.83 9.3 3.5 1.4 8.5 3.5 1.4 1 0 0 1 1 1 0 FAM176 family Thioredoxin PF00085.20 PRP80237.1 - 1.3e-59 198.6 0.0 8.7e-30 102.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 PRP80237.1 - 2.1e-18 67.0 0.0 5.1e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 PRP80237.1 - 3.2e-13 49.7 0.0 5.4e-08 32.5 0.0 2.4 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PRP80237.1 - 3.8e-11 43.4 0.1 0.00028 21.3 0.1 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain LRR_4 PF12799.7 PRP80237.1 - 1.2e-05 25.6 16.5 0.00099 19.5 0.4 7.0 3 2 1 5 5 5 1 Leucine Rich repeats (2 copies) Thioredoxin_8 PF13905.6 PRP80237.1 - 3.4e-05 24.1 0.0 2 8.8 0.0 3.9 2 1 1 3 3 3 2 Thioredoxin-like HyaE PF07449.11 PRP80237.1 - 0.00026 20.9 0.0 0.64 10.0 0.0 2.6 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 PRP80237.1 - 0.0011 18.9 0.1 0.79 9.7 0.0 2.8 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.6 PRP80237.1 - 0.0021 18.2 0.0 0.87 9.8 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like LRR_8 PF13855.6 PRP80237.1 - 0.0035 17.1 10.2 0.05 13.4 0.6 5.9 5 1 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.6 PRP80237.1 - 0.0063 16.5 23.9 9.1 6.6 0.1 8.9 9 0 0 9 9 9 1 Leucine Rich repeat Flagellin_IN PF07196.13 PRP80237.1 - 0.0099 16.1 0.2 0.099 12.9 0.1 2.5 2 0 0 2 2 2 1 Flagellin hook IN motif DUF836 PF05768.14 PRP80237.1 - 0.014 15.7 0.0 8.4 6.9 0.0 4.3 4 1 0 4 4 4 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 PRP80237.1 - 0.021 14.9 0.0 0.39 10.8 0.0 3.0 4 0 0 4 4 4 0 Thioredoxin domain LRR_1 PF00560.33 PRP80237.1 - 0.27 11.9 6.7 17 6.4 0.0 5.9 6 2 0 6 6 4 0 Leucine Rich Repeat PseudoU_synth_2 PF00849.22 PRP80239.1 - 4.8e-18 65.7 0.7 1.5e-16 60.9 0.2 2.2 2 0 0 2 2 2 2 RNA pseudouridylate synthase Vps35 PF03635.17 PRP80240.1 - 1.4e-274 913.2 12.2 1.6e-274 913.0 12.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 LOH1CR12 PF10158.9 PRP80240.1 - 0.045 13.8 0.3 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 Tumour suppressor protein RTP1_C1 PF10363.9 PRP80240.1 - 0.068 13.4 1.9 4.2 7.6 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 VPS13 PF16908.5 PRP80242.1 - 1.2e-65 221.6 9.4 6.5e-65 219.2 0.2 4.4 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 PRP80242.1 - 7.1e-56 188.8 11.0 1.5e-54 184.4 0.6 3.4 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 PRP80242.1 - 2.2e-52 177.8 19.4 1.8e-43 148.7 4.8 5.8 4 1 0 4 4 4 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 PRP80242.1 - 4.6e-43 147.5 3.4 1.7e-38 132.6 1.0 3.2 2 1 1 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 PRP80242.1 - 5.4e-35 120.0 0.4 2.4e-34 117.9 0.4 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 PRP80242.1 - 1.8e-07 31.4 0.0 1.5e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Tropomyosin_1 PF12718.7 PRP80243.1 - 0.073 13.2 11.4 0.64 10.2 4.7 2.6 2 0 0 2 2 2 0 Tropomyosin like PhoU PF01895.19 PRP80243.1 - 0.15 12.6 2.2 0.44 11.0 1.8 2.0 1 1 1 2 2 2 0 PhoU domain DUF334 PF03904.13 PRP80243.1 - 0.29 10.6 5.7 0.086 12.4 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF334) DUF812 PF05667.11 PRP80243.1 - 0.43 9.4 20.1 0.091 11.6 11.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) EMP24_GP25L PF01105.24 PRP80243.1 - 1.6 8.7 5.0 0.33 10.9 0.7 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF465 PF04325.13 PRP80243.1 - 2.3 8.3 8.0 1.3 9.1 1.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) ADIP PF11559.8 PRP80243.1 - 4.3 7.4 11.5 2.3 8.3 2.9 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding XhlA PF10779.9 PRP80243.1 - 5.9 7.2 8.4 13 6.1 2.4 3.3 3 0 0 3 3 3 0 Haemolysin XhlA DnaJ_CXXCXGXG PF00684.19 PRP80244.1 - 5.1e-05 23.5 13.9 0.015 15.6 5.3 2.9 2 0 0 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 PRP80244.1 - 1.7 8.6 16.0 6 6.9 9.6 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein EDR1 PF14381.6 PRP80245.1 - 0.048 13.4 0.3 0.057 13.1 0.3 1.1 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Myb_DNA-binding PF00249.31 PRP80246.1 - 2.4e-13 50.0 0.2 4.6e-13 49.1 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SCA7 PF08313.12 PRP80246.1 - 1.8e-05 24.6 0.2 5.4e-05 23.0 0.2 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain Myb_DNA-bind_6 PF13921.6 PRP80246.1 - 0.00026 21.2 0.2 0.00026 21.2 0.2 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF3819 PF12842.7 PRP80246.1 - 1.9 8.4 12.2 4.8 7.1 12.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Myb_DNA-bind_7 PF15963.5 PRP80246.1 - 2.3 8.2 9.5 0.055 13.4 0.8 2.6 2 1 0 2 2 2 0 Myb DNA-binding like PepSY_TM_like_2 PF16357.5 PRP80246.1 - 3.3 7.7 7.7 7.5 6.5 7.7 1.6 1 0 0 1 1 1 0 Putative PepSY_TM-like DnaJ_CXXCXGXG PF00684.19 PRP80249.1 - 0.00077 19.8 16.6 0.0056 17.0 16.2 2.2 1 1 0 1 1 1 1 DnaJ central domain NOT2_3_5 PF04153.18 PRP80250.1 - 3.9e-32 111.1 3.4 8e-32 110.1 3.4 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family YL1_C PF08265.11 PRP80251.1 - 1.8e-12 46.8 3.9 2.8e-12 46.2 3.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 PRP80251.1 - 0.01 15.7 3.7 0.018 14.9 3.7 1.4 1 0 0 1 1 1 0 HIT zinc finger Arm PF00514.23 PRP80252.1 - 7.2e-06 25.9 1.6 0.0021 18.0 0.0 4.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat KAP PF05804.12 PRP80252.1 - 0.038 12.1 0.0 0.06 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) DUF809 PF05663.11 PRP80252.1 - 1.8 8.7 5.3 1.7 8.8 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Exo_endo_phos PF03372.23 PRP80253.1 - 4.5e-06 26.4 0.0 9.4e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF21 PF01595.20 PRP80255.1 - 8.7e-37 126.5 0.2 1.2e-36 126.0 0.2 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PRP80255.1 - 6.8e-11 42.4 0.1 1.3e-05 25.5 0.0 3.0 3 0 0 3 3 3 2 CBS domain PAP2 PF01569.21 PRP80258.1 - 3.6e-15 55.9 2.7 3.6e-15 55.9 2.7 2.5 3 0 0 3 3 3 1 PAP2 superfamily Pro_isomerase PF00160.21 PRP80259.1 - 2.3e-48 164.5 0.0 3.4e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NARP1 PF12569.8 PRP80260.1 - 1.4 7.7 5.5 1.9 7.3 5.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAS_3 PF08447.12 PRP80261.1 - 1.6e-09 37.9 0.0 2.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 PRP80261.1 - 2.9e-06 27.5 0.0 6.6e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 PRP80261.1 - 0.0028 17.6 0.0 0.077 13.0 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 PRP80261.1 - 0.0045 17.0 0.0 0.032 14.2 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 PRP80261.1 - 0.005 17.1 0.0 0.05 13.9 0.0 2.2 2 0 0 2 2 2 1 PAS fold Brix PF04427.18 PRP80261.1 - 0.013 15.7 0.2 0.14 12.3 0.1 2.1 1 1 1 2 2 2 0 Brix domain Seadorna_VP6 PF07407.11 PRP80261.1 - 0.19 10.7 0.0 0.25 10.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein TPH PF13868.6 PRP80262.1 - 3.6e-46 157.3 147.9 3.6e-46 157.3 147.9 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Sec6 PF06046.13 PRP80263.1 - 1.2e-100 337.6 2.7 2e-100 336.8 2.7 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 GMC_oxred_N PF00732.19 PRP80264.1 - 4.1e-18 65.8 0.0 8e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP80264.1 - 2.9e-12 47.3 0.0 7.4e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DUF3533 PF12051.8 PRP80264.1 - 0.034 13.1 3.8 0.055 12.4 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) XRN_N PF03159.18 PRP80266.1 - 3.1e-69 233.1 0.0 3.1e-69 233.1 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PRP80266.1 - 2.2e-50 171.9 5.6 2.3e-44 152.1 0.9 2.9 2 1 1 3 3 3 2 Xrn1 helical domain RRM_1 PF00076.22 PRP80266.1 - 3.5e-18 65.2 0.1 6.7e-18 64.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA_4 PF14555.6 PRP80266.1 - 2.3e-09 36.9 0.1 4.9e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain RRM_occluded PF16842.5 PRP80266.1 - 0.0012 18.6 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif RL PF17797.1 PRP80266.1 - 0.032 14.2 0.1 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 RL domain TAP_C PF03943.13 PRP80266.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain APO_RNA-bind PF05634.11 PRP80266.1 - 0.071 12.5 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 APO RNA-binding PHM7_cyt PF14703.6 PRP80266.1 - 2.3 8.4 6.3 3.2 8.0 0.6 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter LRR_4 PF12799.7 PRP80267.1 - 1.9e-08 34.5 27.9 0.0011 19.3 0.1 9.6 6 1 6 13 13 13 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP80267.1 - 3.1e-08 33.0 27.7 0.52 10.5 0.0 12.0 13 0 0 13 13 13 2 Leucine Rich repeat LRR_8 PF13855.6 PRP80267.1 - 0.033 14.0 12.7 2.1 8.2 0.3 6.5 6 1 1 7 7 7 0 Leucine rich repeat U79_P34 PF03064.16 PRP80267.1 - 0.22 10.8 14.9 0.43 9.9 11.6 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 DUF1682 PF07946.14 PRP80267.1 - 0.27 10.4 14.2 0.47 9.6 14.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Spt20 PF12090.8 PRP80267.1 - 0.58 9.7 16.3 0.96 9.0 16.3 1.3 1 0 0 1 1 1 0 Spt20 family PA26 PF04636.13 PRP80267.1 - 2 7.2 10.8 3.9 6.3 10.8 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GPR15L PF15854.5 PRP80268.1 - 1.2 9.4 0.0 1.2 9.4 0.0 2.9 4 0 0 4 4 4 0 G-protein coupled receptor ligand 15 PAN_4 PF14295.6 PRP80269.1 - 4.3e-13 49.0 15.2 1.2e-08 34.7 0.8 3.4 3 0 0 3 3 3 3 PAN domain E_raikovi_mat PF06360.11 PRP80269.1 - 0.13 12.7 6.1 5.4 7.5 0.3 2.7 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone PAN_2 PF08276.11 PRP80269.1 - 0.45 10.7 13.0 1.2 9.3 0.4 2.8 2 1 1 3 3 3 0 PAN-like domain ArfGap PF01412.18 PRP80270.1 - 9.1e-37 125.7 0.3 9.1e-37 125.7 0.3 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 PRP80270.1 - 6.3e-08 33.1 3.4 2.1e-06 28.2 1.3 3.0 2 0 0 2 2 2 1 PH domain Sec20 PF03908.13 PRP80270.1 - 0.18 11.7 1.0 0.61 10.0 1.0 1.9 1 0 0 1 1 1 0 Sec20 TetR_C_24 PF17932.1 PRP80271.1 - 0.03 14.6 0.2 0.07 13.4 0.2 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CENP-F_leu_zip PF10473.9 PRP80271.1 - 0.033 14.2 0.5 0.033 14.2 0.5 2.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MIT PF04212.18 PRP80271.1 - 0.035 14.2 7.1 0.31 11.2 4.8 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain V-SNARE PF05008.15 PRP80271.1 - 1.9 9.0 7.8 0.1 13.0 1.2 2.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus SpoU_methylase PF00588.19 PRP80273.1 - 3.4e-21 75.9 0.0 9.9e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family AIG1 PF04548.16 PRP80273.1 - 1.6e-05 24.4 2.7 0.007 15.7 0.1 2.7 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 PRP80273.1 - 6.6e-05 23.0 0.0 0.0002 21.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PRP80273.1 - 0.0034 17.5 0.1 0.0034 17.5 0.1 2.9 3 0 0 3 3 3 1 Dynamin family FapA PF03961.13 PRP80273.1 - 0.48 9.0 3.0 6.2 5.3 1.9 2.5 2 0 0 2 2 2 0 Flagellar Assembly Protein A TraB PF01963.17 PRP80274.1 - 1.6e-05 25.0 0.0 2.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 TraB family Guanylate_cyc PF00211.20 PRP80276.1 - 4.2e-33 114.5 0.9 9.6e-33 113.3 0.1 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain dCache_1 PF02743.18 PRP80276.1 - 4.3e-07 30.0 0.8 9.6e-07 28.8 0.8 1.6 1 1 0 1 1 1 1 Cache domain Phage_holin_7_1 PF16081.5 PRP80276.1 - 0.059 13.5 0.7 0.13 12.4 0.7 1.6 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family DUF4064 PF13273.6 PRP80276.1 - 7.1 7.0 6.6 5.6 7.3 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) RdRP PF05183.12 PRP80277.1 - 7.8e-116 388.1 0.0 1.3e-115 387.3 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase ACOX PF01756.19 PRP80277.1 - 3e-43 147.5 0.0 6e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PRP80277.1 - 2.1e-15 56.7 0.0 1.5e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 PRP80277.1 - 2.4e-05 24.9 0.0 6.5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 PRP80277.1 - 0.065 13.4 0.0 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain MA3 PF02847.17 PRP80279.1 - 5e-33 113.5 1.9 5.1e-18 65.1 0.1 2.3 2 0 0 2 2 2 2 MA3 domain AF0941-like PF14591.6 PRP80279.1 - 0.0064 17.0 1.0 0.029 14.9 0.2 2.3 2 0 0 2 2 2 1 AF0941-like IpaB_EvcA PF03278.13 PRP80279.1 - 0.0087 15.8 0.0 0.18 11.5 0.0 2.4 2 1 0 2 2 2 1 IpaB/EvcA family CDC45 PF02724.14 PRP80279.1 - 0.0096 14.3 0.0 0.012 14.0 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein PHtD_u1 PF16645.5 PRP80279.1 - 0.041 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein SPOB_a PF14689.6 PRP80279.1 - 0.079 12.7 0.5 0.24 11.1 0.5 1.9 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain SPRY PF00622.28 PRP80280.1 - 2.6e-12 46.9 1.6 5.5e-05 23.3 0.1 2.2 2 0 0 2 2 2 2 SPRY domain DUF722 PF05263.11 PRP80283.1 - 0.075 13.3 1.7 0.63 10.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF722) GAS PF13851.6 PRP80284.1 - 0.0076 15.6 3.4 0.019 14.3 3.2 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF5057 PF16480.5 PRP80284.1 - 0.081 12.3 1.4 0.087 12.2 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5057) HNH_2 PF13391.6 PRP80286.1 - 2.8e-08 33.8 0.2 1.2e-07 31.8 0.1 2.2 2 1 0 2 2 2 1 HNH endonuclease GAS PF13851.6 PRP80287.1 - 0.0041 16.5 14.2 0.0059 16.0 14.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FAM92 PF06730.11 PRP80288.1 - 1.1e-10 41.4 5.6 2e-10 40.5 5.6 1.4 1 0 0 1 1 1 1 FAM92 protein Phage_TAC_4 PF08748.11 PRP80288.1 - 0.083 13.2 0.0 0.39 11.0 0.0 2.2 1 0 0 1 1 1 0 Phage tail assembly chaperone Arm PF00514.23 PRP80289.1 - 9.9e-39 130.2 50.0 0.0014 18.6 0.0 22.9 24 1 1 25 25 24 9 Armadillo/beta-catenin-like repeat WW PF00397.26 PRP80289.1 - 3.2e-22 78.3 8.6 1.3e-11 44.4 0.3 2.5 2 0 0 2 2 2 2 WW domain FYVE PF01363.21 PRP80289.1 - 6.7e-14 51.8 16.7 1.5e-13 50.6 16.7 1.6 1 0 0 1 1 1 1 FYVE zinc finger HEAT_2 PF13646.6 PRP80289.1 - 3.3e-11 43.4 11.4 1.4 9.3 0.0 11.2 8 3 3 13 13 13 3 HEAT repeats HEAT PF02985.22 PRP80289.1 - 1.6e-10 40.3 7.9 1.3 9.5 0.0 10.6 11 0 0 11 11 9 3 HEAT repeat HEAT_EZ PF13513.6 PRP80289.1 - 2.5e-06 27.9 9.9 2.8 8.5 0.0 9.3 9 1 1 10 10 9 1 HEAT-like repeat Arm_2 PF04826.13 PRP80289.1 - 7.5e-06 25.6 0.2 7.5e-06 25.6 0.2 8.9 7 2 2 9 9 9 2 Armadillo-like V-ATPase_H_N PF03224.14 PRP80289.1 - 0.00013 21.3 29.9 0.0024 17.2 0.3 6.8 4 2 1 5 5 5 1 V-ATPase subunit H CTNNBL PF08216.11 PRP80289.1 - 0.00057 20.0 1.8 1.2 9.3 0.0 5.0 3 1 1 4 4 4 1 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 PRP80289.1 - 0.18 11.8 13.7 2.7 8.1 0.1 6.4 9 0 0 9 9 7 0 Spinocerebellar ataxia type 10 protein domain VHS PF00790.19 PRP80289.1 - 0.18 11.6 1.3 4.8 7.0 0.3 3.2 2 1 0 2 2 2 0 VHS domain Cnd1 PF12717.7 PRP80289.1 - 0.25 11.4 23.7 1.8 8.6 0.2 8.2 8 2 1 10 10 10 0 non-SMC mitotic condensation complex subunit 1 FYVE_2 PF02318.16 PRP80289.1 - 0.56 10.4 9.6 1.4 9.1 9.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger V-ATPase_H_C PF11698.8 PRP80289.1 - 0.78 9.9 8.2 1.6e+02 2.4 0.0 6.6 9 0 0 9 9 7 0 V-ATPase subunit H RTP1_C1 PF10363.9 PRP80289.1 - 1.1 9.5 8.6 54 4.0 0.2 5.2 5 1 1 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 PRP80289.1 - 2.4 8.0 15.4 6.1 6.7 0.1 6.5 6 2 0 6 6 6 0 Domain of unknown function (DUF3385) ADIP PF11559.8 PRP80289.1 - 3.2 7.8 6.5 0.38 10.8 0.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SIL1 PF16782.5 PRP80289.1 - 4.2 6.5 10.6 12 5.0 0.4 5.1 6 0 0 6 6 6 0 Nucleotide exchange factor SIL1 Homeobox_KN PF05920.11 PRP80291.1 - 4.5e-07 29.7 7.1 7.1e-06 25.8 7.1 2.3 1 1 0 1 1 1 1 Homeobox KN domain Meis_PKNOX_N PF16493.5 PRP80291.1 - 0.15 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Glyco_hydro_65m PF03632.15 PRP80292.1 - 4e-110 368.3 2.5 5.5e-110 367.8 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 PRP80292.1 - 1.6e-44 152.3 0.8 3.1e-44 151.3 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain MIP PF00230.20 PRP80292.1 - 9.8e-42 143.2 12.1 1.7e-41 142.4 12.1 1.3 1 0 0 1 1 1 1 Major intrinsic protein HAD_2 PF13419.6 PRP80292.1 - 1.7e-18 67.3 0.0 6.7e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP80292.1 - 5.4e-11 43.2 0.2 2e-10 41.3 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP80292.1 - 0.048 13.7 0.0 0.097 12.7 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF3471 PF11954.8 PRP80292.1 - 0.1 13.1 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) SAP PF02037.27 PRP80293.1 - 5.7e-07 29.1 0.4 1.5e-05 24.6 0.4 3.2 3 0 0 3 3 3 1 SAP domain DUF772 PF05598.11 PRP80293.1 - 0.13 12.2 0.1 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Transposase domain (DUF772) LRR_6 PF13516.6 PRP80293.1 - 0.42 10.8 7.2 8.6 6.7 0.0 4.7 6 0 0 6 6 6 0 Leucine Rich repeat GTP_EFTU PF00009.27 PRP80294.1 - 4.2e-23 81.9 0.1 4.2e-23 81.9 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PRP80294.1 - 1.3e-19 70.3 0.7 6.5e-19 68.0 0.1 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 PRP80294.1 - 5.3e-13 49.2 2.1 7.2e-08 32.7 0.1 4.6 4 0 0 4 4 4 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 PRP80294.1 - 1.1e-10 41.2 0.0 4.3e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 PRP80294.1 - 9.3e-05 22.5 0.1 9.3e-05 22.5 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Inhibitor_I48 PF10467.9 PRP80294.1 - 0.061 13.2 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin Lipase_GDSL_3 PF14606.6 PRP80294.1 - 2.7 8.1 7.1 0.5 10.5 0.1 2.5 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.25 PRP80295.1 - 6e-50 170.1 0.0 6e-50 170.1 0.0 3.5 3 2 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80295.1 - 3.4e-35 121.6 0.0 3.4e-35 121.6 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase Ank PF00023.30 PRP80295.1 - 3e-26 90.7 2.9 2.1e-05 24.7 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 PRP80295.1 - 1e-23 83.7 4.2 1.2e-09 38.6 0.7 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80295.1 - 3.9e-23 81.5 4.6 4.2e-09 36.8 0.2 5.9 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP80295.1 - 3.6e-22 78.1 5.2 1.5e-06 28.4 0.1 4.6 2 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80295.1 - 5.9e-21 72.3 1.5 0.00082 19.7 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat NAD_binding_10 PF13460.6 PRP80296.1 - 1.4e-17 64.2 0.0 2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PRP80296.1 - 4.5e-05 23.1 0.0 0.007 16.0 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 PRP80296.1 - 0.0061 15.6 0.1 0.0092 15.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PRP80296.1 - 0.0074 15.5 0.0 0.017 14.3 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 PRP80296.1 - 0.02 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ER PF01133.17 PRP80297.1 - 1.1e-26 92.6 0.0 2.4e-26 91.6 0.0 1.6 1 0 0 1 1 1 1 Enhancer of rudimentary RMI1_N PF08585.12 PRP80297.1 - 1.1e-25 90.7 0.0 1.9e-14 53.9 0.0 2.3 1 1 1 2 2 2 2 RecQ mediated genome instability protein RMI1_C PF16099.5 PRP80297.1 - 4e-19 68.9 0.2 1.1e-18 67.4 0.0 1.8 2 0 0 2 2 2 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Glyco_hydro_18 PF00704.28 PRP80298.1 - 1.5e-61 208.8 0.0 2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.25 PRP80298.1 - 2e-26 92.7 0.1 3.3e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP80298.1 - 4.9e-23 81.9 0.3 7.3e-23 81.3 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP80298.1 - 3e-05 24.0 0.1 6.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP80298.1 - 0.00023 21.1 0.2 0.00057 19.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Aldo_ket_red PF00248.21 PRP80299.1 - 3.4e-31 108.5 0.1 1.7e-20 73.4 0.0 3.2 2 1 0 2 2 2 2 Aldo/keto reductase family SKG6 PF08693.10 PRP80300.1 - 0.0051 16.2 0.1 0.0093 15.3 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PRP80300.1 - 0.0054 17.6 0.0 0.0065 17.3 0.0 1.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 PRP80300.1 - 0.021 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Adeno_E3_CR2 PF02439.15 PRP80300.1 - 0.03 14.1 1.0 0.048 13.4 1.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MLANA PF14991.6 PRP80300.1 - 0.037 14.3 0.0 0.042 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein melan-A Herpes_gE PF02480.16 PRP80300.1 - 0.08 11.7 0.0 0.081 11.7 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SNRNP27 PF08648.12 PRP80301.1 - 5.3e-24 84.0 2.5 1.6e-23 82.5 2.5 1.9 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF3464 PF11947.8 PRP80301.1 - 0.45 10.3 3.5 0.76 9.5 3.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4778 PF16008.5 PRP80301.1 - 0.63 10.0 4.4 0.96 9.4 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) RR_TM4-6 PF06459.12 PRP80301.1 - 1.6 8.5 18.0 1.9 8.2 18.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 PRP80301.1 - 1.8 8.6 13.7 2.6 8.1 13.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.14 PRP80301.1 - 5.5 5.1 8.6 6.3 5.0 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_1 PF00515.28 PRP80303.1 - 1.2e-11 43.9 2.4 7.9e-06 25.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP80303.1 - 7.1e-09 35.1 0.6 0.00043 20.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP80303.1 - 6.2e-06 26.0 1.0 0.0033 17.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP80303.1 - 1.3e-05 25.3 0.8 4.3e-05 23.7 0.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP80303.1 - 6.1e-05 23.5 0.2 0.00072 20.0 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP80303.1 - 0.00013 22.1 0.1 2.9 8.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP80303.1 - 0.00019 22.0 0.0 0.00053 20.6 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP80303.1 - 0.0035 17.9 0.5 1.5 9.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP80303.1 - 0.005 17.6 0.0 0.017 15.9 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 PRP80303.1 - 0.07 13.5 0.1 1.2 9.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP80303.1 - 0.14 11.8 0.2 1.1 9.0 0.1 2.3 1 1 1 2 2 2 0 TPR repeat TPR_7 PF13176.6 PRP80303.1 - 0.16 12.0 0.0 7.7 6.8 0.0 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat Cofilin_ADF PF00241.20 PRP80304.1 - 4.4e-26 91.1 0.0 5.8e-12 45.5 0.1 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF3430 PF11912.8 PRP80306.1 - 0.00066 19.8 4.9 0.0008 19.5 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) AMP-binding PF00501.28 PRP80307.1 - 1.6e-77 260.9 0.0 2.3e-77 260.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP80307.1 - 5.7e-21 75.3 1.9 9.9e-21 74.5 1.9 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain OmpW PF03922.14 PRP80307.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 OmpW family Brix PF04427.18 PRP80308.1 - 1.2e-42 146.2 0.1 1.8e-42 145.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF1284 PF06935.11 PRP80308.1 - 0.015 15.8 1.2 0.034 14.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) PPL5 PF18168.1 PRP80308.1 - 0.12 11.6 6.4 0.2 10.9 6.4 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Serinc PF03348.15 PRP80308.1 - 0.31 9.9 2.0 0.44 9.4 2.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4820 PF16091.5 PRP80308.1 - 0.57 9.5 6.2 0.88 8.9 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) AIF_C PF14721.6 PRP80308.1 - 0.88 9.9 4.9 1.2 9.5 3.2 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIEZO PF15917.5 PRP80308.1 - 2.2 7.7 12.3 4.6 6.6 12.3 1.5 1 0 0 1 1 1 0 Piezo Presenilin PF01080.17 PRP80308.1 - 4.3 6.0 11.2 6.6 5.4 11.2 1.3 1 0 0 1 1 1 0 Presenilin Astro_capsid_p PF12226.8 PRP80308.1 - 5.1 6.1 10.2 8.2 5.5 10.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RR_TM4-6 PF06459.12 PRP80308.1 - 8.7 6.1 23.5 0.42 10.4 18.1 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PI3Ka PF00613.20 PRP80309.1 - 6.9e-55 185.3 0.1 1.2e-54 184.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 PRP80309.1 - 3.2e-47 161.4 0.1 5.6e-46 157.4 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 PRP80309.1 - 7e-08 32.6 0.4 1.6e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 PRP80309.1 - 0.0004 20.3 0.0 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 PRP80309.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Peptidase_S8 PF00082.22 PRP80310.1 - 8.3e-40 136.9 8.0 8.3e-40 136.9 8.0 2.2 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 PRP80310.1 - 5.2e-09 36.6 1.0 1.2e-08 35.5 0.3 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 GDPD PF03009.17 PRP80310.1 - 1e-08 35.2 0.6 6.2e-07 29.4 0.0 2.6 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 PRP80310.1 - 0.19 12.2 1.2 1.1 9.9 0.7 2.4 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Period_C PF12114.8 PRP80311.1 - 9.8 5.7 8.9 12 5.4 8.3 1.5 1 1 0 1 1 1 0 Period protein 2/3C-terminal region DUF4139 PF13598.6 PRP80312.1 - 1.8e-46 158.5 0.1 1.8e-46 158.5 0.1 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 PRP80312.1 - 1.7e-16 60.4 3.0 1.7e-16 60.4 3.0 2.0 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) Top6b_C PF18000.1 PRP80312.1 - 0.052 13.7 3.9 1.2 9.4 0.9 2.9 2 1 0 2 2 2 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain DUF4407 PF14362.6 PRP80312.1 - 0.93 8.8 6.0 1.3 8.3 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Synaptobrevin PF00957.21 PRP80314.1 - 3.6e-30 103.6 5.3 4e-30 103.5 5.3 1.0 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 PRP80314.1 - 0.0037 16.8 1.3 0.0037 16.8 1.3 1.7 1 1 1 2 2 2 1 fzo-like conserved region DUF2275 PF10039.9 PRP80314.1 - 0.0096 16.0 1.3 0.015 15.4 1.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2275) DUF2207 PF09972.9 PRP80314.1 - 0.092 11.5 0.1 0.099 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ferlin_C PF16165.5 PRP80314.1 - 6.6 6.7 7.6 6.7 6.6 6.6 1.4 1 1 0 1 1 1 0 Ferlin C-terminus Pkinase PF00069.25 PRP80315.1 - 9e-54 182.6 0.3 1.6e-53 181.8 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80315.1 - 1.8e-22 79.9 0.0 3.3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Synaptobrevin PF00957.21 PRP80315.1 - 3.5e-13 49.1 2.6 1e-12 47.6 2.2 2.0 2 0 0 2 2 2 1 Synaptobrevin Kinase-like PF14531.6 PRP80315.1 - 0.0043 16.4 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 PRP80315.1 - 0.0078 15.8 0.1 0.025 14.2 0.1 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase ANAPC4_WD40 PF12894.7 PRP80315.1 - 0.0098 16.2 0.0 23 5.3 0.0 4.1 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP80315.1 - 0.18 12.8 0.5 1.4 9.9 0.4 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat PSK_trans_fac PF07704.11 PRP80315.1 - 8.5 7.2 12.2 1.3 9.9 5.1 2.8 3 0 0 3 3 3 0 Rv0623-like transcription factor Homeodomain PF00046.29 PRP80316.1 - 7.4e-14 51.3 3.7 1.1e-13 50.8 3.7 1.3 1 0 0 1 1 1 1 Homeodomain Catalase-rel PF06628.12 PRP80316.1 - 0.0013 18.9 0.1 0.004 17.3 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Homeobox_KN PF05920.11 PRP80316.1 - 0.0092 15.9 0.8 0.017 15.0 0.8 1.5 1 0 0 1 1 1 1 Homeobox KN domain Codanin-1_C PF15296.6 PRP80316.1 - 0.031 14.4 0.2 0.031 14.4 0.2 2.1 1 1 1 2 2 2 0 Codanin-1 C-terminus Pinin_SDK_memA PF04696.13 PRP80317.1 - 6.1e-19 68.4 8.5 6.1e-19 68.4 8.5 4.0 2 2 1 3 3 3 1 pinin/SDK/memA/ protein conserved region Herpes_UL25 PF01499.16 PRP80317.1 - 0.13 10.8 0.0 0.13 10.8 0.0 2.3 3 0 0 3 3 3 0 Herpesvirus UL25 family Homeodomain PF00046.29 PRP80319.1 - 1e-10 41.3 6.6 1e-07 31.7 0.3 2.3 2 0 0 2 2 2 2 Homeodomain Homez PF11569.8 PRP80319.1 - 0.024 14.1 0.6 0.046 13.2 0.1 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 PRP80319.1 - 0.11 12.4 1.8 0.45 10.5 1.8 2.0 1 1 0 1 1 1 0 Homeobox KN domain Ras PF00071.22 PRP80320.1 - 3.8e-60 202.2 1.8 4.6e-60 201.9 1.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP80320.1 - 9.5e-32 109.7 2.1 1.8e-31 108.9 0.2 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP80320.1 - 3e-16 59.4 0.6 3.7e-16 59.1 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP80320.1 - 1.4e-07 31.5 2.8 0.0075 16.2 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP80320.1 - 1.4e-06 28.0 0.8 4.5e-06 26.3 0.8 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP80320.1 - 6.6e-06 26.2 0.2 1.3e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 PRP80320.1 - 0.00011 21.6 0.6 0.00059 19.2 0.0 1.9 2 0 0 2 2 2 1 Septin Gtr1_RagA PF04670.12 PRP80320.1 - 0.00016 21.1 0.6 0.00024 20.6 0.6 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 PRP80320.1 - 0.0003 20.1 5.3 0.046 12.9 2.5 2.9 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 PRP80320.1 - 0.0023 18.3 0.0 0.0038 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 PRP80320.1 - 0.0028 17.1 0.7 0.0046 16.4 0.7 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.6 PRP80320.1 - 0.012 15.4 0.0 0.017 14.8 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 PRP80320.1 - 0.014 15.2 0.0 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 PRP80320.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PRP80320.1 - 0.033 14.7 1.2 0.068 13.7 1.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 PRP80320.1 - 0.033 14.6 0.4 1.1 9.7 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 PRP80320.1 - 0.052 13.1 0.2 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Hpr_kinase_C PF07475.12 PRP80320.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.14 PRP80320.1 - 0.11 12.6 0.1 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP80320.1 - 0.12 12.6 0.1 0.38 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain LRR_6 PF13516.6 PRP80321.1 - 7.3e-12 44.3 9.9 0.015 15.3 0.0 5.5 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 PRP80321.1 - 0.0001 22.6 3.1 0.45 11.0 0.0 4.0 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP80321.1 - 0.0083 16.5 5.4 6.5 7.7 0.0 5.6 7 2 0 7 7 7 1 Leucine Rich Repeat UCH PF00443.29 PRP80322.1 - 1e-52 179.2 0.4 2.5e-52 177.9 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP80322.1 - 8.9e-30 104.4 0.4 3.3e-29 102.5 0.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 PRP80322.1 - 1.2e-08 34.6 0.4 1.2e-06 28.0 0.1 2.5 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 Ubiquitin_2 PF14560.6 PRP80322.1 - 0.0014 19.0 6.0 6.9 7.2 0.0 4.8 5 0 0 5 5 5 2 Ubiquitin-like domain ubiquitin PF00240.23 PRP80322.1 - 0.018 14.8 0.5 1.6 8.6 0.0 3.5 4 0 0 4 4 4 0 Ubiquitin family USP7_C2 PF14533.6 PRP80322.1 - 0.072 12.8 0.1 0.072 12.8 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-specific protease C-terminal DUF3592 PF12158.8 PRP80324.1 - 7.3e-14 52.1 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Neuraminidase PF18413.1 PRP80324.1 - 0.0073 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Neuraminidase-like domain F_actin_bind PF08919.10 PRP80326.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 F-actin binding TPR_2 PF07719.17 PRP80327.1 - 3.9e-19 67.1 18.0 0.47 10.7 0.0 10.8 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 PRP80327.1 - 1.5e-15 56.2 23.2 0.077 12.8 0.1 10.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 PRP80327.1 - 9.1e-13 47.9 8.1 0.14 13.1 0.1 8.1 7 2 2 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP80327.1 - 5e-12 45.0 19.9 0.024 14.8 0.1 10.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP80327.1 - 1.4e-11 44.7 11.4 0.36 11.4 0.3 6.7 6 1 0 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 PRP80327.1 - 4e-09 36.6 10.8 0.091 13.1 0.0 7.5 6 3 1 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP80327.1 - 3.6e-08 33.5 10.3 0.066 13.4 0.0 5.7 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 PRP80327.1 - 2e-06 27.5 4.2 0.37 10.7 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP80327.1 - 1.4e-05 25.7 0.1 18 6.1 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP80327.1 - 3.4e-05 23.6 8.6 0.32 11.1 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP80327.1 - 0.00016 21.8 7.3 2.4 8.3 0.5 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP80327.1 - 0.00078 19.1 0.3 3.1 7.6 0.0 5.4 5 1 1 6 6 6 1 TPR repeat TPR_15 PF13429.6 PRP80327.1 - 0.0028 16.9 1.1 0.0028 16.9 1.1 4.8 3 2 3 6 6 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PRP80327.1 - 0.0036 17.3 7.0 2.8 8.0 0.4 4.8 3 1 2 5 5 5 1 Putative TPR-like repeat TPR_17 PF13431.6 PRP80327.1 - 0.052 13.9 1.2 6.6 7.4 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP80327.1 - 0.062 12.7 7.9 0.12 11.7 0.7 3.8 2 2 1 3 3 3 0 MalT-like TPR region TPR_20 PF14561.6 PRP80327.1 - 0.12 12.7 3.6 7.9 6.9 0.1 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 PRP80327.1 - 0.44 11.3 2.1 39 5.1 0.0 3.1 3 0 0 3 3 2 0 Sel1 repeat ERO1 PF04137.15 PRP80328.1 - 6.2e-109 364.4 0.4 8e-109 364.1 0.4 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF72 PF01904.18 PRP80329.1 - 1e-41 143.4 0.0 1.5e-41 142.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF72 Acetyltransf_1 PF00583.25 PRP80329.1 - 1.7e-06 28.3 0.0 3.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PRP80329.1 - 0.00092 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 PRP80329.1 - 0.0097 15.6 0.0 0.87 9.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Peptidase_C1 PF00112.23 PRP80331.1 - 3e-57 194.2 4.7 3e-57 194.2 4.7 2.0 2 0 0 2 2 2 1 Papain family cysteine protease CAP PF00188.26 PRP80331.1 - 1.8e-13 51.4 3.0 1.8e-13 51.4 3.0 2.9 3 0 0 3 3 3 1 Cysteine-rich secretory protein family WSC PF01822.19 PRP80331.1 - 1.8e-11 44.0 15.6 1.8e-11 44.0 15.6 3.8 4 0 0 4 4 4 2 WSC domain Peptidase_C1_2 PF03051.15 PRP80331.1 - 0.0011 17.9 3.0 0.028 13.2 1.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Tim17 PF02466.19 PRP80332.1 - 1e-10 42.0 0.5 9.8e-10 38.8 0.4 2.0 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family IlvB_leader PF08049.11 PRP80332.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 IlvB leader peptide DUF1269 PF06897.12 PRP80332.1 - 0.98 9.7 3.2 1.5 9.1 2.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) DFRP_C PF16543.5 PRP80333.1 - 1.4e-13 51.1 7.2 1.4e-13 51.1 7.2 3.5 3 2 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 PRP80333.1 - 3.5e-07 30.9 15.7 2.8e-05 24.8 4.8 4.0 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 PRP80333.1 - 2.1e-05 24.3 1.2 2.1e-05 24.3 1.2 2.6 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP80333.1 - 0.00011 22.1 12.7 0.0002 21.3 5.8 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 PRP80333.1 - 0.00028 20.6 7.0 0.0015 18.2 1.9 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PRP80333.1 - 0.055 14.0 11.8 0.29 11.7 4.8 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 PRP80333.1 - 1.4 9.2 6.4 0.41 10.9 0.4 2.6 2 1 1 3 3 3 0 Zinc-finger containing family PFU PF09070.11 PRP80334.1 - 0.0005 20.3 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Glyco_hydro_76 PF03663.14 PRP80335.1 - 1e-24 87.7 5.2 3.1e-21 76.3 0.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 RicinB_lectin_2 PF14200.6 PRP80335.1 - 1.7e-16 60.7 4.3 3.5e-11 43.7 0.2 3.4 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like PAN_4 PF14295.6 PRP80335.1 - 3.4e-11 42.9 5.4 5.8e-10 38.9 2.2 2.7 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PRP80335.1 - 9e-05 22.4 2.0 0.00065 19.6 0.7 2.8 3 0 0 3 3 3 1 PAN domain Ricin_B_lectin PF00652.22 PRP80335.1 - 0.00034 20.9 0.1 0.00034 20.9 0.1 2.9 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain C5-epim_C PF06662.13 PRP80335.1 - 0.0066 16.0 0.1 0.016 14.7 0.1 1.7 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus LRR_8 PF13855.6 PRP80336.1 - 1.3e-56 188.2 68.8 6.3e-10 38.7 0.1 10.0 4 3 7 11 11 11 11 Leucine rich repeat PP2C PF00481.21 PRP80336.1 - 2.4e-48 165.0 0.0 3.7e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 PRP80336.1 - 4.1e-42 141.5 78.5 5.5e-07 29.8 0.0 11.6 9 1 1 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP80336.1 - 6.8e-13 48.5 34.6 0.00076 19.0 1.1 5.2 1 1 3 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 PRP80336.1 - 7.8e-09 35.6 6.3 0.086 12.8 0.1 4.2 2 1 2 4 4 4 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PRP80336.1 - 3.1e-07 30.0 61.9 0.44 11.3 0.1 15.5 19 0 0 19 19 19 4 Leucine Rich Repeat LRR_6 PF13516.6 PRP80336.1 - 0.00012 21.8 60.1 0.3 11.2 0.1 15.5 17 0 0 17 17 17 4 Leucine Rich repeat PP2C_2 PF13672.6 PRP80336.1 - 0.00069 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP80336.1 - 0.073 13.0 0.0 0.26 11.2 0.0 1.9 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) WD40_4 PF16300.5 PRP80337.1 - 1.8e-13 50.1 0.5 3.3e-13 49.3 0.5 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 PRP80337.1 - 2.6e-09 37.5 0.5 0.0005 20.8 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80337.1 - 6.5e-07 29.6 0.0 0.032 14.5 0.0 3.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 PRP80337.1 - 3.6e-06 26.7 0.0 9.3e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Ge1_WD40 PF16529.5 PRP80337.1 - 0.008 15.2 0.0 1.9 7.4 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Phage_CI_C PF16452.5 PRP80338.1 - 0.15 12.4 0.0 17 5.8 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage CI repressor C-terminal domain BRCT_2 PF16589.5 PRP80339.1 - 2.5e-06 27.8 0.0 0.00073 19.9 0.0 3.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PRP80339.1 - 0.0036 17.6 0.1 0.05 14.0 0.0 3.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PRP80339.1 - 0.1 12.6 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain DUF4250 PF14056.6 PRP80339.1 - 0.55 10.2 3.7 1.5 8.8 0.5 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) AlbA_2 PF04326.14 PRP80340.1 - 0.0014 19.0 0.0 0.0045 17.3 0.0 1.8 1 0 0 1 1 1 1 Putative DNA-binding domain Gin PF10764.9 PRP80340.1 - 0.16 12.0 1.9 0.95 9.5 1.5 2.6 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin ABC_tran PF00005.27 PRP80341.1 - 1.9e-47 161.2 0.1 4.6e-23 82.2 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 PRP80341.1 - 3.1e-22 78.4 6.4 3.9e-21 74.9 6.7 2.4 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PRP80341.1 - 9e-21 75.0 3.3 3.1e-05 23.9 0.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PRP80341.1 - 9.2e-09 35.1 5.8 0.0066 15.9 0.2 4.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PRP80341.1 - 2.6e-07 30.3 0.0 0.023 14.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 PRP80341.1 - 1.1e-05 25.9 0.0 0.055 13.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 PRP80341.1 - 1.7e-05 24.7 5.3 0.085 12.6 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 PRP80341.1 - 2.1e-05 25.1 9.4 0.031 14.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.6 PRP80341.1 - 3.4e-05 23.9 0.1 0.57 10.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 PRP80341.1 - 6.8e-05 23.2 0.0 0.083 13.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 PRP80341.1 - 8.2e-05 23.2 0.0 0.6 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PRP80341.1 - 8.6e-05 22.8 0.0 0.22 11.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PRP80341.1 - 0.00014 21.8 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PRP80341.1 - 0.00015 22.2 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 PRP80341.1 - 0.00017 21.5 0.6 0.84 9.5 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 PRP80341.1 - 0.00025 21.3 0.2 0.5 10.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 PRP80341.1 - 0.00036 20.6 0.1 0.89 9.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PRP80341.1 - 0.00038 20.2 1.1 0.2 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 PRP80341.1 - 0.00059 19.9 0.0 0.5 10.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 PRP80341.1 - 0.0012 18.6 0.0 0.67 9.7 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 PRP80341.1 - 0.0013 18.8 0.0 0.94 9.5 0.0 3.1 2 1 1 3 3 3 1 Dynamin family NB-ARC PF00931.22 PRP80341.1 - 0.0019 17.4 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_30 PF13604.6 PRP80341.1 - 0.0023 17.7 0.0 0.31 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 PRP80341.1 - 0.0025 17.7 0.0 0.049 13.5 0.0 2.3 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 PRP80341.1 - 0.0029 17.6 0.8 0.14 12.2 0.0 2.8 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 PRP80341.1 - 0.0036 16.6 0.1 0.32 10.2 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.22 PRP80341.1 - 0.0046 17.3 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 PRP80341.1 - 0.0064 16.1 0.0 0.83 9.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 PRP80341.1 - 0.0093 15.0 1.7 0.29 10.1 0.0 3.0 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 PRP80341.1 - 0.017 14.8 0.7 0.4 10.3 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 PRP80341.1 - 0.018 15.5 0.4 4.3 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 PRP80341.1 - 0.027 14.1 0.5 8.8 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.15 PRP80341.1 - 0.033 14.1 0.0 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 PRP80341.1 - 0.034 13.9 0.0 5.6 6.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein MukB PF04310.12 PRP80341.1 - 0.049 13.4 0.1 2.8 7.7 0.0 2.6 3 0 0 3 3 2 0 MukB N-terminal cobW PF02492.19 PRP80341.1 - 0.058 13.0 0.9 1.2 8.7 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 PRP80341.1 - 0.064 12.4 0.0 9.7 5.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Arf PF00025.21 PRP80341.1 - 0.075 12.5 0.1 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF87 PF01935.17 PRP80341.1 - 0.084 13.0 1.4 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 PRP80341.1 - 0.09 12.5 0.0 0.9 9.2 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 PRP80341.1 - 0.1 12.1 0.0 4.3 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 PRP80341.1 - 0.11 12.7 0.1 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Alg14 PF08660.11 PRP80342.1 - 4.2e-48 163.6 0.0 5.9e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 PRP80342.1 - 4.6e-21 75.5 0.0 6.6e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain PhoD PF09423.10 PRP80343.1 - 1.5e-13 50.5 0.0 9.7e-12 44.6 0.0 2.4 1 1 0 1 1 1 1 PhoD-like phosphatase PARP PF00644.20 PRP80347.1 - 1.1e-22 80.5 0.1 2.3e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain LEAP-2 PF07359.11 PRP80348.1 - 0.022 14.6 0.2 0.022 14.6 0.2 33.9 26 10 18 44 44 44 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Beta_elim_lyase PF01212.21 PRP80351.1 - 5e-71 239.4 0.0 6.4e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 PRP80351.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 PRP80351.1 - 0.016 13.7 0.0 0.027 13.0 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TTL PF03133.15 PRP80351.1 - 0.097 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family AbiEi_2 PF09952.9 PRP80351.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Inositol_P PF00459.25 PRP80352.1 - 7.1e-71 238.9 0.1 8.5e-71 238.6 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family SAP PF02037.27 PRP80353.1 - 2e-10 40.1 1.2 3.8e-10 39.3 1.2 1.5 1 0 0 1 1 1 1 SAP domain DUF1664 PF07889.12 PRP80354.1 - 0.0058 16.7 4.3 0.0058 16.7 4.3 7.0 3 2 3 7 7 7 2 Protein of unknown function (DUF1664) Cullin_Nedd8 PF10557.9 PRP80355.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Cullin protein neddylation domain F-box PF00646.33 PRP80356.1 - 4.1e-05 23.3 1.4 4.1e-05 23.3 1.4 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP80356.1 - 0.0031 17.4 3.5 0.0063 16.4 3.5 1.6 1 0 0 1 1 1 1 F-box-like Pkinase_Tyr PF07714.17 PRP80357.1 - 7.9e-48 163.0 0.0 1.1e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80357.1 - 4.7e-44 150.7 0.0 7e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kelch_1 PF01344.25 PRP80357.1 - 2e-05 24.1 11.5 0.014 14.9 0.2 5.6 5 0 0 5 5 5 2 Kelch motif DUF5122 PF17164.4 PRP80357.1 - 0.33 11.3 31.6 0.83 10.0 0.3 8.5 9 0 0 9 9 9 0 Domain of unknown function (DUF5122) beta-propeller Kelch_4 PF13418.6 PRP80357.1 - 0.44 10.6 7.7 0.9 9.6 0.1 4.9 5 1 1 6 6 6 0 Galactose oxidase, central domain Rax2 PF12768.7 PRP80357.1 - 0.97 8.8 10.7 1 8.8 0.3 4.8 5 1 0 5 5 5 0 Cortical protein marker for cell polarity Kelch_2 PF07646.15 PRP80357.1 - 1.7 8.8 17.1 5.1 7.2 0.1 7.6 10 0 0 10 10 10 0 Kelch motif LVIVD PF08309.11 PRP80357.1 - 4.8 6.6 10.6 3.9 6.9 0.4 3.7 3 0 0 3 3 3 0 LVIVD repeat Kelch_6 PF13964.6 PRP80357.1 - 9.5 6.7 11.8 2.5 8.5 0.1 5.2 5 0 0 5 5 5 0 Kelch motif F-box PF00646.33 PRP80358.1 - 2.6e-05 24.0 0.3 6.1e-05 22.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain DUF3447 PF11929.8 PRP80358.1 - 0.0017 18.3 0.1 21 5.2 0.0 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3447) F-box-like PF12937.7 PRP80358.1 - 0.0038 17.1 3.0 0.0086 15.9 3.0 1.6 1 0 0 1 1 1 1 F-box-like p450 PF00067.22 PRP80359.1 - 5e-16 58.5 0.3 4.6e-13 48.7 0.5 2.2 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_17 PF00332.18 PRP80359.1 - 2.3e-11 43.9 0.7 8.7e-11 42.0 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 X8 PF07983.13 PRP80359.1 - 4.3e-08 33.7 4.4 1.7e-07 31.8 3.3 2.4 2 0 0 2 2 2 1 X8 domain F-box PF00646.33 PRP80361.1 - 5.8e-07 29.2 0.3 1.8e-06 27.6 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP80361.1 - 0.00023 21.0 2.2 0.00055 19.8 2.2 1.7 1 0 0 1 1 1 1 F-box-like YfbU PF03887.14 PRP80361.1 - 0.16 12.0 0.8 17 5.4 0.0 2.8 3 0 0 3 3 3 0 YfbU domain F-box PF00646.33 PRP80364.1 - 4.8e-05 23.1 0.1 0.00012 21.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 PRP80364.1 - 0.00036 21.0 0.1 0.62 10.7 0.0 4.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP80364.1 - 0.0033 17.3 0.3 0.0067 16.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like Ank_3 PF13606.6 PRP80364.1 - 0.017 15.6 0.0 55 4.8 0.0 5.3 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 PRP80364.1 - 0.047 14.3 0.0 9.7 6.9 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) ADH_zinc_N PF00107.26 PRP80365.1 - 2.1e-17 63.3 0.0 3.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP80365.1 - 3.8e-14 53.9 0.0 9.3e-14 52.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP80365.1 - 9.9e-11 41.5 0.0 1.7e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KTI12 PF08433.10 PRP80366.1 - 3.7e-15 56.1 0.9 2.8e-13 49.9 0.9 2.1 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 PRP80366.1 - 2.4e-06 27.8 1.0 0.0016 18.6 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 PRP80366.1 - 0.00038 21.0 0.1 0.00038 21.0 0.1 2.2 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP80366.1 - 0.00043 20.7 0.1 0.0017 18.7 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.10 PRP80366.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 PRP80366.1 - 0.017 15.4 0.6 0.23 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 PRP80366.1 - 0.056 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 PRP80366.1 - 0.51 10.8 0.0 0.51 10.8 0.0 2.7 2 2 0 2 2 2 0 AAA domain LAG1-DNAbind PF09271.11 PRP80367.1 - 0.0099 16.5 0.0 0.024 15.3 0.0 1.4 1 1 0 1 1 1 1 LAG1, DNA binding F-box PF00646.33 PRP80368.1 - 0.001 18.9 1.2 0.0036 17.1 0.5 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP80368.1 - 0.3 11.0 1.5 0.79 9.7 1.5 1.7 1 0 0 1 1 1 0 F-box-like GCFC PF07842.12 PRP80369.1 - 2.1e-54 185.0 15.4 3.4e-54 184.3 15.4 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Na_H_Exchanger PF00999.21 PRP80369.1 - 6.9e-51 173.2 19.6 9.8e-51 172.7 19.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family G-patch PF01585.23 PRP80369.1 - 5.3e-15 55.0 4.7 1.1e-14 54.0 4.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PRP80369.1 - 2e-06 27.8 2.9 2e-06 27.8 2.9 2.7 3 0 0 3 3 3 1 G-patch domain Phage_holin_3_3 PF16083.5 PRP80369.1 - 0.02 15.0 1.8 1.2 9.3 0.1 3.1 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III Nha1_C PF08619.10 PRP80369.1 - 0.58 9.3 34.7 0.049 12.8 4.4 3.0 2 1 1 3 3 3 0 Alkali metal cation/H+ antiporter Nha1 C terminus EMP70 PF02990.16 PRP80369.1 - 3.2 6.3 9.7 0.064 11.9 0.4 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 Phage_holin_5_2 PF16079.5 PRP80369.1 - 7.6 6.9 6.9 36 4.8 1.1 2.7 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V EMP24_GP25L PF01105.24 PRP80370.1 - 2.9e-44 151.2 0.1 5e-44 150.4 0.1 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LRR_8 PF13855.6 PRP80370.1 - 1.9e-21 75.5 52.6 1.1e-07 31.5 4.9 6.3 3 2 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 PRP80370.1 - 1.1e-18 66.9 54.8 3e-06 27.4 3.2 6.9 3 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP80370.1 - 0.00038 20.6 52.1 0.21 12.3 0.5 11.8 10 3 1 11 11 11 3 Leucine Rich Repeat SAP PF02037.27 PRP80372.1 - 1.6e-06 27.7 0.0 5.3e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 SAP domain eIF-3c_N PF05470.12 PRP80372.1 - 0.072 11.4 9.4 0.094 11.0 9.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SAPS PF04499.15 PRP80372.1 - 1.6 7.4 9.7 1.9 7.2 9.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 PRP80372.1 - 2.5 7.8 16.6 2.9 7.7 16.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TLP-20 PF06088.11 PRP80372.1 - 4.9 7.0 11.2 6.4 6.6 11.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PRC2_HTH_1 PF18118.1 PRP80372.1 - 6.4 7.6 12.3 19 6.1 0.2 2.2 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain DUF4498 PF14926.6 PRP80374.1 - 1e-20 74.1 0.1 2.6e-11 43.3 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4498) zf-MYND PF01753.18 PRP80376.1 - 0.00094 19.2 7.5 0.0019 18.2 7.5 1.6 1 0 0 1 1 1 1 MYND finger XPC-binding PF09280.11 PRP80376.1 - 0.022 14.5 1.8 8.2 6.2 0.1 5.1 3 0 0 3 3 3 0 XPC-binding domain zf-Mss51 PF13824.6 PRP80376.1 - 0.065 13.3 5.6 0.27 11.3 5.6 2.1 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Syntaxin-18_N PF10496.9 PRP80376.1 - 0.7 10.2 7.9 2.1 8.6 0.2 5.6 4 0 0 4 4 4 0 SNARE-complex protein Syntaxin-18 N-terminus DUF2605 PF10792.9 PRP80376.1 - 2.4 8.2 4.7 11 6.0 0.7 4.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) WD40 PF00400.32 PRP80377.1 - 1.1e-29 102.0 17.0 6.8e-07 29.9 0.0 7.3 7 2 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80377.1 - 4.2e-07 30.2 1.6 0.34 11.2 0.0 4.2 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP80377.1 - 0.00034 19.4 1.5 0.035 12.8 0.0 3.5 2 1 1 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PRP80377.1 - 0.00047 19.0 1.6 0.19 10.4 0.1 2.8 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_3 PF13570.6 PRP80377.1 - 0.051 14.1 0.0 70 4.1 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Ge1_WD40 PF16529.5 PRP80377.1 - 0.1 11.5 3.5 8.4 5.2 0.0 3.2 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pkinase_Tyr PF07714.17 PRP80378.1 - 8.5e-53 179.3 0.0 9.9e-31 107.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP80378.1 - 2.3e-48 164.8 0.0 4.1e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP80378.1 - 1.4e-12 47.5 0.0 2.8e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 PRP80378.1 - 0.0016 18.4 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cbl_N2 PF02761.14 PRP80378.1 - 0.014 16.1 0.2 0.029 15.1 0.2 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain Pkinase_fungal PF17667.1 PRP80378.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_M50B PF13398.6 PRP80379.1 - 0.0041 16.8 0.9 0.005 16.5 0.9 1.1 1 0 0 1 1 1 1 Peptidase M50B-like PsbI PF02532.14 PRP80379.1 - 0.27 11.2 3.3 0.59 10.1 3.3 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) WW PF00397.26 PRP80380.1 - 3.1 8.0 7.9 14 5.8 2.3 2.7 2 0 0 2 2 2 0 WW domain DUF515 PF04415.12 PRP80380.1 - 8.2 4.7 16.1 15 3.9 16.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2254 PF10011.9 PRP80381.1 - 2.6e-11 42.9 6.8 4.2e-11 42.3 6.8 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) DUF1129 PF06570.11 PRP80381.1 - 0.75 9.2 5.4 1.5 8.3 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) F-box PF00646.33 PRP80382.1 - 1.3e-05 24.9 0.3 1.3e-05 24.9 0.3 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP80382.1 - 0.00053 19.8 2.2 0.00053 19.8 2.2 2.2 3 0 0 3 3 3 1 F-box-like TMEM135_C_rich PF15982.5 PRP80383.1 - 2.2e-06 28.3 0.2 5.9e-06 26.9 0.2 1.7 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Methyltransf_11 PF08241.12 PRP80384.1 - 1.3e-22 80.2 0.0 2.6e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP80384.1 - 6.4e-22 78.0 0.0 8.4e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP80384.1 - 4e-21 75.5 0.0 3.1e-20 72.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP80384.1 - 2.1e-15 57.3 0.0 4.7e-15 56.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP80384.1 - 2.3e-14 53.3 0.0 3.7e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PRP80384.1 - 9.3e-11 41.8 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP80384.1 - 4.7e-07 29.5 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 PRP80384.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 PRP80384.1 - 0.00017 21.4 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 PRP80384.1 - 0.00045 19.7 0.0 0.3 10.5 0.0 2.3 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 PRP80384.1 - 0.00059 19.3 0.0 0.0012 18.3 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 PRP80384.1 - 0.0015 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PRP80384.1 - 0.0039 16.5 0.0 0.0059 15.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 PRP80384.1 - 0.0069 15.0 0.0 0.01 14.5 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 PRP80384.1 - 0.0072 15.5 0.0 0.0099 15.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_18 PF12847.7 PRP80384.1 - 0.0075 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 PRP80384.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_8 PF05148.15 PRP80384.1 - 0.0086 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.20 PRP80384.1 - 0.0097 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 PRP80384.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF938 PF06080.12 PRP80384.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 PRP80384.1 - 0.076 13.1 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase NSP16 PF06460.12 PRP80384.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NSP16 DUF3684 PF12449.8 PRP80386.1 - 1.4e-251 837.8 2.5 1.5e-246 821.1 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 PRP80386.1 - 0.0019 18.0 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IQ_SEC7_PH PF16453.5 PRP80386.1 - 0.32 11.0 1.9 0.72 9.8 0.7 2.1 2 0 0 2 2 2 0 PH domain Peptidase_C1 PF00112.23 PRP80387.1 - 3.6e-24 86.1 0.9 6.6e-24 85.2 0.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 PRP80387.1 - 0.00013 20.9 0.1 0.00022 20.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase C1-like family BrnA_antitoxin PF14384.6 PRP80387.1 - 0.018 15.5 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system PAN_4 PF14295.6 PRP80387.1 - 5.6 7.0 10.7 1.4 8.9 2.2 3.6 3 1 0 3 3 3 0 PAN domain Carb_anhydrase PF00194.21 PRP80388.1 - 1.3e-44 152.6 5.5 2.5e-44 151.7 5.5 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Q_salvage PF10343.9 PRP80389.1 - 2.9e-100 335.5 0.0 4.2e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family FG-GAP_2 PF14312.6 PRP80389.1 - 0.00083 19.6 0.3 0.00083 19.6 0.3 4.9 6 0 0 6 6 6 2 FG-GAP repeat Toxin_12 PF07740.12 PRP80389.1 - 2.2 9.0 9.3 5.8 7.7 9.3 1.7 1 0 0 1 1 1 0 Ion channel inhibitory toxin Conotoxin_I2 PF17557.2 PRP80389.1 - 4.3 7.5 11.8 12 6.1 11.8 1.7 1 0 0 1 1 1 0 I2-superfamily conotoxins CAP59_mtransfer PF11735.8 PRP80391.1 - 1.1e-47 162.8 0.0 1.3e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Piwi PF02171.17 PRP80392.1 - 2.1e-49 168.4 0.0 3e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 PRP80392.1 - 5.9e-09 35.9 0.2 1.1e-08 34.9 0.2 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 PRP80392.1 - 2.8e-05 23.7 0.0 7.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 PRP80392.1 - 0.0012 19.5 0.1 0.0038 17.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute Guanylate_cyc PF00211.20 PRP80396.1 - 4.6e-23 81.8 0.2 1.8e-22 79.8 0.2 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Galactosyl_T PF01762.21 PRP80396.1 - 7.2e-09 35.7 0.0 1.7e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 Galactosyltransferase LPP PF04728.13 PRP80396.1 - 0.039 14.4 15.2 0.23 11.9 1.2 4.3 4 0 0 4 4 4 0 Lipoprotein leucine-zipper UPF0449 PF15136.6 PRP80396.1 - 0.045 14.2 0.2 0.045 14.2 0.2 5.4 3 2 3 7 7 7 0 Uncharacterised protein family UPF0449 SapB_1 PF05184.15 PRP80397.1 - 4.6e-21 74.5 16.1 7.3e-08 32.3 1.1 5.0 5 0 0 5 5 5 3 Saposin-like type B, region 1 SapB_2 PF03489.17 PRP80397.1 - 4.7e-15 55.4 8.3 2.8e-06 27.3 0.6 3.7 3 0 0 3 3 3 3 Saposin-like type B, region 2 Mce4_CUP1 PF11887.8 PRP80397.1 - 0.0012 18.3 0.6 1.3 8.4 0.0 2.9 2 1 1 3 3 3 2 Cholesterol uptake porter CUP1 of Mce4, putative Sec34 PF04136.15 PRP80397.1 - 0.025 14.4 0.4 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Sec34-like family PEPcase PF00311.17 PRP80397.1 - 0.096 10.7 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Sgf11 PF08209.11 PRP80398.1 - 0.065 12.8 0.3 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) GAIN_A PF18619.1 PRP80398.1 - 0.21 11.8 2.4 7.1 6.9 0.1 3.6 3 0 0 3 3 3 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A BCIP PF13862.6 PRP80398.1 - 2.7 7.7 6.4 0.64 9.8 2.1 2.0 2 0 0 2 2 2 0 p21-C-terminal region-binding protein Adaptin_binding PF10199.9 PRP80398.1 - 5.2 7.7 14.3 0.93 10.1 0.6 3.0 1 1 2 3 3 3 0 Alpha and gamma adaptin binding protein p34 PUL PF08324.11 PRP80399.1 - 3e-42 144.7 4.1 4.1e-42 144.3 4.1 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 PRP80399.1 - 6.8e-21 74.2 0.0 2.2e-20 72.5 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin STI1 PF17830.1 PRP80399.1 - 7.9e-10 38.5 2.3 2.4e-09 37.0 2.3 1.8 1 0 0 1 1 1 1 STI1 domain Thioredoxin_2 PF13098.6 PRP80399.1 - 5.1e-05 23.7 0.1 0.016 15.6 0.1 2.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PRP80399.1 - 0.0026 18.0 0.1 0.015 15.6 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 PRP80399.1 - 0.0069 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PRP80399.1 - 0.027 14.4 0.1 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.6 PRP80399.1 - 0.066 13.0 0.8 0.18 11.6 0.0 2.2 2 1 0 2 2 2 0 Thioredoxin SEA PF01390.20 PRP80399.1 - 0.068 13.3 3.4 0.087 12.9 0.9 2.2 2 0 0 2 2 2 0 SEA domain DUF4065 PF13274.6 PRP80399.1 - 0.081 13.8 0.5 0.27 12.1 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4065) RPN6_N PF18055.1 PRP80399.1 - 0.18 12.2 1.5 11 6.3 0.1 2.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain RhoGEF67_u2 PF16614.5 PRP80399.1 - 0.21 11.7 1.7 0.22 11.6 0.2 1.9 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 TssO PF17561.2 PRP80399.1 - 2.9 8.0 7.0 1.6 8.8 0.0 2.9 2 1 1 3 3 3 0 Type VI secretion system, TssO Mur_ligase_M PF08245.12 PRP80400.1 - 1.5e-10 41.4 0.7 1e-09 38.7 0.7 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 PRP80400.1 - 0.0034 17.6 0.1 0.041 14.1 0.0 2.4 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain PEMT PF04191.13 PRP80401.1 - 1.7e-06 28.4 0.7 4.1e-06 27.1 0.7 1.7 1 1 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 PRP80401.1 - 0.00012 22.1 1.8 0.0002 21.3 1.8 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 PRP80401.1 - 0.00028 20.5 1.0 0.00041 19.9 1.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 PRP80401.1 - 0.028 14.8 0.2 0.028 14.8 0.2 1.7 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2542 PF10808.8 PRP80401.1 - 0.16 12.4 5.0 0.18 12.3 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2542) TraF_2 PF13729.6 PRP80402.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Urease_beta PF00699.20 PRP80402.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Urease beta subunit Nicastrin PF05450.15 PRP80402.1 - 0.26 10.7 0.7 14 5.0 0.0 2.1 1 1 1 2 2 2 0 Nicastrin 2-oxoacid_dh PF00198.23 PRP80404.1 - 3.9e-79 265.4 0.0 5.8e-79 264.8 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PRP80404.1 - 7.6e-21 73.7 1.0 3.1e-20 71.8 0.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 PRP80404.1 - 2.2e-14 53.5 0.0 2.8e-13 49.9 0.0 2.8 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 PRP80404.1 - 0.00013 21.7 0.6 0.29 11.0 0.0 3.3 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.6 PRP80404.1 - 0.0068 17.1 0.0 0.14 12.9 0.0 2.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 PRP80404.1 - 0.02 14.1 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_2 PF12700.7 PRP80404.1 - 0.048 12.4 0.2 0.1 11.3 0.1 1.5 2 0 0 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 PRP80404.1 - 0.09 12.7 0.3 0.53 10.2 0.0 2.1 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF5488 PF17590.2 PRP80404.1 - 0.12 12.1 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Flavokinase PF01687.17 PRP80405.1 - 2e-31 108.6 0.0 5.4e-31 107.2 0.0 1.8 1 0 0 1 1 1 1 Riboflavin kinase DUF883 PF05957.13 PRP80405.1 - 0.001 19.6 106.5 0.61 10.7 5.5 10.7 2 1 10 12 12 12 10 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 PRP80405.1 - 0.0017 18.3 112.6 0.05 13.5 28.8 4.9 1 1 3 4 4 4 3 Apolipoprotein A1/A4/E domain YtxH PF12732.7 PRP80405.1 - 0.0076 16.8 16.5 0.0076 16.8 16.5 12.3 2 2 8 10 10 10 8 YtxH-like protein Pox_F16 PF04708.12 PRP80405.1 - 0.1 12.0 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Poxvirus F16 protein NopRA1 PF16201.5 PRP80405.1 - 0.2 11.2 0.8 0.56 9.8 0.8 1.7 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 Yip1 PF04893.17 PRP80406.1 - 1.5e-09 37.8 27.1 9.5e-09 35.2 26.5 2.3 1 1 1 2 2 2 1 Yip1 domain Peptidase_U4 PF03419.13 PRP80406.1 - 1.8 7.8 12.9 2.3 7.4 12.9 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF3040 PF11239.8 PRP80406.1 - 3.8 7.9 9.6 0.18 12.1 1.4 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF3040) Glu_cyclase_2 PF05096.12 PRP80407.1 - 7.4e-85 284.4 3.5 1.3e-84 283.6 3.5 1.3 1 0 0 1 1 1 1 Glutamine cyclotransferase Pkinase_Tyr PF07714.17 PRP80407.1 - 8.8e-72 241.5 0.0 1.3e-71 241.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80407.1 - 9.1e-46 156.3 0.0 1.7e-45 155.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RRM_1 PF00076.22 PRP80407.1 - 8.1e-24 83.2 0.2 3.9e-11 42.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.6 PRP80407.1 - 7.8e-12 44.8 16.6 9.6e-05 22.1 0.3 5.1 4 0 0 4 4 4 3 Leucine rich repeat Glyco_hydro_15 PF00723.21 PRP80407.1 - 4.5e-05 22.4 0.0 0.00052 18.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 LRR_4 PF12799.7 PRP80407.1 - 0.0001 22.6 22.2 0.00068 20.0 0.3 5.5 4 1 1 5 5 4 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PRP80407.1 - 0.0029 17.9 0.8 0.01 16.1 0.8 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain TMEM154 PF15102.6 PRP80407.1 - 0.0035 17.3 0.2 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family Pkinase_fungal PF17667.1 PRP80407.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Collectrin PF16959.5 PRP80407.1 - 0.022 14.6 0.4 0.05 13.4 0.4 1.6 1 0 0 1 1 1 0 Renal amino acid transporter RRM_7 PF16367.5 PRP80407.1 - 0.036 14.2 0.0 16 5.7 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif Kdo PF06293.14 PRP80407.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_q2 PF00420.24 PRP80407.1 - 0.078 12.6 0.4 0.31 10.7 0.2 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Orf78 PF06024.12 PRP80407.1 - 0.13 12.5 0.0 0.84 10.0 0.0 2.2 2 0 0 2 2 2 0 Orf78 (ac78) CD34_antigen PF06365.12 PRP80407.1 - 0.14 11.7 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 CD34/Podocalyxin family EphA2_TM PF14575.6 PRP80407.1 - 0.16 12.9 3.9 1.5 9.8 0.4 2.9 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PRP80407.1 - 6.4 6.9 7.1 3.6 7.7 1.8 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment S4 PF01479.25 PRP80408.1 - 2e-12 46.6 1.3 5.4e-12 45.2 1.3 1.8 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 PRP80408.1 - 4.1e-05 24.4 4.0 0.00062 20.6 4.0 2.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L7Ae PF01248.26 PRP80409.1 - 1e-11 44.4 0.5 7.2e-11 41.7 0.1 2.5 2 1 1 3 3 3 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2475 PF10629.9 PRP80410.1 - 4.1e-11 42.9 6.5 0.00018 21.6 0.2 4.5 4 0 0 4 4 4 4 Protein of unknown function (DUF2475) Ank_2 PF12796.7 PRP80411.1 - 1.1e-48 163.7 4.7 2.1e-13 50.6 0.4 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 PRP80411.1 - 1e-26 92.1 3.2 0.00038 20.8 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 PRP80411.1 - 1.7e-26 92.2 5.2 1.5e-09 38.2 0.4 5.3 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP80411.1 - 4.6e-26 90.5 2.9 2.2e-06 27.8 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80411.1 - 2.8e-21 73.3 0.4 0.0012 19.2 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Catalase PF00199.19 PRP80412.1 - 4.6e-136 453.9 0.0 5.7e-136 453.6 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 PRP80412.1 - 1.6e-10 41.0 0.0 3.7e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive UQ_con PF00179.26 PRP80413.1 - 1e-39 135.4 0.0 1.5e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PRP80413.1 - 0.021 14.7 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain TagA PF12561.8 PRP80413.1 - 0.031 14.7 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 ToxR activated gene A lipoprotein domain RWD PF05773.22 PRP80413.1 - 0.034 14.4 0.1 0.046 14.0 0.1 1.3 1 1 0 1 1 1 0 RWD domain SNARE_assoc PF09335.11 PRP80414.1 - 3e-23 82.6 1.7 3e-23 82.6 1.7 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4200 PF13863.6 PRP80415.1 - 5.1e-16 59.1 23.4 5.1e-16 59.1 23.4 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) ApoO PF09769.9 PRP80415.1 - 3.8 7.5 5.7 7 6.6 0.2 2.9 2 1 1 3 3 3 0 Apolipoprotein O WXG100 PF06013.12 PRP80415.1 - 4.2 7.7 7.6 4.7 7.5 0.1 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG TPR_MLP1_2 PF07926.12 PRP80415.1 - 5.2 7.2 31.1 0.91 9.6 14.2 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Vps51 PF08700.11 PRP80416.1 - 4.4e-26 90.8 6.6 1.8e-25 88.9 3.6 3.4 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.6 PRP80416.1 - 4.6e-17 62.4 3.2 3.1e-16 59.7 3.2 2.6 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 PRP80416.1 - 7.1e-14 51.2 11.8 1.6e-13 50.0 11.8 1.5 1 0 0 1 1 1 1 Dor1-like family Vps54_N PF10475.9 PRP80416.1 - 7e-08 32.1 9.6 7e-08 32.1 9.6 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Vps53_N PF04100.12 PRP80416.1 - 3e-05 23.2 5.8 0.00015 20.9 5.8 2.4 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.11 PRP80416.1 - 8.6e-05 22.6 5.7 9.9e-05 22.4 2.3 2.8 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2408 PF10303.9 PRP80416.1 - 0.001 19.6 6.2 0.0015 19.1 0.5 3.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2408) COG5 PF10392.9 PRP80416.1 - 0.0071 16.5 1.3 0.0071 16.5 1.3 2.9 4 0 0 4 4 4 1 Golgi transport complex subunit 5 NdhM PF10664.9 PRP80416.1 - 0.11 12.7 0.8 1 9.7 0.0 2.7 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M CENP-Q PF13094.6 PRP80416.1 - 0.33 11.1 6.7 0.36 11.0 1.1 2.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GIT_CC PF16559.5 PRP80416.1 - 0.41 10.5 4.7 0.26 11.2 1.1 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ING PF12998.7 PRP80416.1 - 0.47 11.1 7.9 17 6.1 0.7 4.3 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF5376 PF17346.2 PRP80416.1 - 0.62 10.4 4.2 3.2 8.1 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5376) Sec8_exocyst PF04048.14 PRP80416.1 - 6.8 6.6 7.9 2.2 8.1 0.7 3.5 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain ATG7_N PF16420.5 PRP80417.1 - 1.5e-77 261.2 0.5 2.1e-77 260.7 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 PRP80417.1 - 3.2e-48 164.2 0.0 5.5e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 PRP80417.1 - 0.0084 16.2 0.1 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 PRP80417.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MORN PF02493.20 PRP80418.1 - 2.2e-46 153.0 71.5 1.5e-06 27.8 1.0 11.3 11 0 0 11 11 11 10 MORN repeat DUF1107 PF06526.12 PRP80418.1 - 9.6 6.2 7.3 19 5.3 0.4 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1107) adh_short PF00106.25 PRP80419.1 - 4.2e-41 140.5 0.0 5.7e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP80419.1 - 1.6e-24 86.8 0.6 1.5e-12 47.6 0.5 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP80419.1 - 7.3e-08 32.5 1.2 1e-05 25.5 0.5 2.2 2 0 0 2 2 2 2 KR domain 2-Hacid_dh_C PF02826.19 PRP80419.1 - 0.015 14.7 0.1 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PRP80419.1 - 0.025 14.8 0.4 0.044 14.0 0.4 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 PRP80419.1 - 0.065 12.7 0.1 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RA PF00788.23 PRP80419.1 - 0.19 12.4 0.0 0.35 11.5 0.0 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Grg1 PF11034.8 PRP80420.1 - 2.9e-31 107.5 9.6 4e-31 107.0 9.6 1.2 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DUF4100 PF13352.6 PRP80420.1 - 0.011 15.5 2.3 0.015 15.1 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) Rap_GAP PF02145.15 PRP80421.1 - 6e-16 58.5 0.0 2.2e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Rap/ran-GAP Pkinase PF00069.25 PRP80422.1 - 1.7e-52 178.4 0.0 4.9e-32 111.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80422.1 - 6e-22 78.2 0.0 1.8e-17 63.5 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PRP80422.1 - 2.4e-05 24.4 0.1 0.034 14.0 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP80422.1 - 0.0083 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 PRP80422.1 - 0.019 14.5 0.1 0.041 13.5 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 PRP80422.1 - 0.02 14.2 0.2 0.055 12.8 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP80422.1 - 0.069 12.8 0.1 0.16 11.5 0.1 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Glyco_hydro_85 PF03644.13 PRP80424.1 - 9.2e-67 225.6 14.5 1.6e-65 221.5 9.8 3.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 85 FBA PF04300.13 PRP80424.1 - 4.6e-16 59.0 1.3 6.8e-16 58.5 0.3 1.7 2 0 0 2 2 2 1 F-box associated region ThiF PF00899.21 PRP80425.1 - 6.5e-29 101.0 0.0 8.5e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family E1_4HB PF16191.5 PRP80425.1 - 2.8e-05 24.2 0.0 8.1e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 PRP80425.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 PRP80426.1 - 4e-36 125.3 0.0 5.1e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP80426.1 - 1e-10 41.7 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP80426.1 - 2e-05 24.4 0.0 0.0003 20.5 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PRP80426.1 - 0.00019 20.8 0.1 0.00038 19.8 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 PRP80426.1 - 0.00027 21.0 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding TMEM206 PF15122.6 PRP80426.1 - 0.26 10.4 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 TMEM206 protein family RRM_2 PF04059.12 PRP80427.1 - 1e-49 166.7 1.6 2.2e-49 165.6 1.6 1.6 1 0 0 1 1 1 1 RNA recognition motif 2 Pkinase PF00069.25 PRP80427.1 - 1.2e-46 159.3 0.0 2e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RRM_1 PF00076.22 PRP80427.1 - 4.5e-29 100.1 3.1 1.2e-12 47.5 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.17 PRP80427.1 - 1.6e-19 70.3 0.0 2.4e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_5 PF13893.6 PRP80427.1 - 1.1e-10 41.2 0.0 0.00015 21.4 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PRP80427.1 - 1.2e-06 28.3 0.0 0.00047 20.0 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif Kdo PF06293.14 PRP80427.1 - 7.8e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BRAP2 PF07576.12 PRP80427.1 - 0.0009 19.4 1.5 0.0014 18.8 0.3 2.0 2 0 0 2 2 1 1 BRCA1-associated protein 2 Pkinase_fungal PF17667.1 PRP80427.1 - 0.0012 17.8 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Smg4_UPF3 PF03467.15 PRP80427.1 - 0.0058 16.7 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family Kinase-like PF14531.6 PRP80427.1 - 0.013 14.8 0.0 0.041 13.2 0.0 1.8 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 PRP80427.1 - 0.026 14.5 0.0 0.089 12.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family PHM7_cyt PF14703.6 PRP80427.1 - 0.037 14.3 1.7 15 5.8 0.0 3.5 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter BRCT PF00533.26 PRP80428.1 - 4.3e-64 212.9 2.2 5.2e-11 42.8 0.1 8.0 9 0 0 9 9 9 7 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP80428.1 - 2e-53 178.8 0.2 2.3e-07 31.1 0.0 8.5 7 1 1 8 8 8 7 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PRP80428.1 - 1.6e-51 172.1 4.8 3.6e-16 58.9 0.1 8.0 8 0 0 8 8 8 5 twin BRCT domain LIG3_BRCT PF16759.5 PRP80428.1 - 5.3e-20 71.5 0.0 0.0047 17.2 0.0 7.5 7 0 0 7 7 7 5 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 PRP80428.1 - 1.6e-11 43.9 0.2 0.025 14.5 0.0 6.5 7 0 0 7 7 7 4 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 PRP80428.1 - 2.3e-08 34.0 0.3 0.62 10.2 0.0 7.5 8 0 0 8 8 8 1 BRCA1 C Terminus (BRCT) domain Exo_endo_phos PF03372.23 PRP80430.1 - 2.9e-09 36.8 0.0 4.6e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family adh_short PF00106.25 PRP80431.1 - 5.1e-51 172.9 0.2 6e-51 172.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP80431.1 - 2e-43 148.6 0.1 2.6e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP80431.1 - 2.3e-12 47.2 0.5 3.9e-12 46.5 0.5 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 PRP80431.1 - 2.5e-05 24.2 0.2 3.7e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 PRP80431.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 PRP80431.1 - 0.00042 19.4 0.1 0.00058 19.0 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.6 PRP80431.1 - 0.00055 20.6 0.1 0.00092 19.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 PRP80431.1 - 0.00095 19.4 0.4 0.0017 18.6 0.4 1.4 1 0 0 1 1 1 1 TrkA-N domain Ubie_methyltran PF01209.18 PRP80431.1 - 0.0031 16.9 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PRP80431.1 - 0.0086 15.6 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain YjeF_N PF03853.15 PRP80431.1 - 0.0091 15.9 0.2 0.014 15.3 0.2 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus F420_oxidored PF03807.17 PRP80431.1 - 0.019 15.5 0.2 0.035 14.7 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_12 PF08242.12 PRP80431.1 - 0.031 15.0 0.0 0.053 14.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain RmlD_sub_bind PF04321.17 PRP80431.1 - 0.034 13.2 0.1 0.055 12.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_31 PF13847.6 PRP80431.1 - 0.04 13.7 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 PRP80431.1 - 0.049 13.1 0.8 0.096 12.1 0.2 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.14 PRP80431.1 - 0.05 13.2 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LpxI_N PF17930.1 PRP80431.1 - 0.052 13.4 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 LpxI N-terminal domain DFP PF04127.15 PRP80431.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PTH2 PF01981.16 PRP80431.1 - 0.089 13.1 1.4 2.5 8.4 0.0 2.7 2 1 1 3 3 3 0 Peptidyl-tRNA hydrolase PTH2 Pyr_redox PF00070.27 PRP80431.1 - 0.092 13.3 0.5 0.19 12.3 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_11 PF08241.12 PRP80431.1 - 0.12 13.1 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pho88 PF10032.9 PRP80432.1 - 5.8e-39 133.2 2.2 6.6e-39 133.1 2.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TssO PF17561.2 PRP80432.1 - 0.06 13.4 0.0 0.095 12.8 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO T2SSM PF04612.12 PRP80432.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M WD40 PF00400.32 PRP80433.1 - 2e-37 126.5 29.4 1.1e-05 26.1 0.1 9.9 10 0 0 10 10 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80433.1 - 1.1e-17 64.1 0.9 0.023 15.0 0.0 6.7 3 3 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PRP80433.1 - 6.9e-10 38.9 1.7 5.2e-05 22.9 0.6 4.0 1 1 2 3 3 3 3 PQQ-like domain WD40_like PF17005.5 PRP80433.1 - 2.2e-09 37.1 0.2 0.015 14.6 0.1 5.1 2 1 4 6 6 6 2 WD40-like domain PQQ_3 PF13570.6 PRP80433.1 - 1.2e-06 28.7 4.5 6.1 7.5 0.0 6.9 8 1 1 9 9 8 2 PQQ-like domain eIF2A PF08662.11 PRP80433.1 - 0.00015 21.7 0.0 1.8 8.4 0.0 3.7 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PRP80433.1 - 0.00026 20.9 0.0 0.67 10.0 0.0 4.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 PRP80433.1 - 0.00063 17.9 1.3 1 7.2 0.0 3.6 1 1 3 4 4 4 3 IKI3 family PALB2_WD40 PF16756.5 PRP80433.1 - 0.0057 15.6 7.1 3.5 6.4 0.0 4.4 3 2 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain SGL PF08450.12 PRP80433.1 - 0.012 15.3 0.6 1.9 8.0 0.1 4.2 3 2 1 4 4 4 0 SMP-30/Gluconolactonase/LRE-like region ELYS-bb PF16687.5 PRP80433.1 - 0.047 12.3 0.0 0.28 9.7 0.0 2.0 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Cytochrom_D1 PF02239.16 PRP80433.1 - 0.11 11.0 0.9 13 4.2 0.0 3.8 4 2 2 6 6 6 0 Cytochrome D1 heme domain PQQ PF01011.21 PRP80433.1 - 0.35 10.9 1.4 41 4.3 0.0 4.6 4 0 0 4 4 4 0 PQQ enzyme repeat Rit1_C PF17184.4 PRP80434.1 - 1.8e-72 244.1 0.0 2.4e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 PRP80434.1 - 1.9e-10 41.0 0.0 3.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Bcr-Abl_Oligo PF09036.10 PRP80435.1 - 0.051 13.6 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain PP2C PF00481.21 PRP80436.1 - 3.8e-50 170.9 0.0 4.5e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PRP80436.1 - 2.6e-06 27.2 0.0 2.1e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Ras PF00071.22 PRP80437.1 - 3.8e-40 137.1 0.2 2.4e-39 134.5 0.2 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP80437.1 - 4.4e-19 68.9 0.5 3.9e-18 65.8 0.5 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP80437.1 - 1.6e-08 34.2 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 PRP80437.1 - 4.2e-06 27.1 0.0 1.2e-05 25.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 PRP80437.1 - 6.5e-05 22.4 0.0 8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PRP80437.1 - 0.00031 21.2 0.0 0.00063 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 PRP80437.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 PRP80437.1 - 0.0022 17.7 0.1 0.027 14.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 PRP80437.1 - 0.0023 17.7 0.0 0.0073 16.1 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MCM PF00493.23 PRP80437.1 - 0.0033 16.6 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain NACHT PF05729.12 PRP80437.1 - 0.0042 17.0 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 PRP80437.1 - 0.0061 17.0 0.0 0.24 11.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PRP80437.1 - 0.0067 16.3 0.0 0.91 9.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PRP80437.1 - 0.0082 15.7 0.1 0.6 9.6 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MobB PF03205.14 PRP80437.1 - 0.0096 15.8 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 PRP80437.1 - 0.011 15.8 0.0 0.047 13.8 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 PRP80437.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 PRP80437.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PRP80437.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 PRP80437.1 - 0.03 13.6 0.0 0.068 12.4 0.0 1.5 2 0 0 2 2 2 0 Septin cobW PF02492.19 PRP80437.1 - 0.042 13.4 0.1 3.3 7.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 PRP80437.1 - 0.042 13.0 0.0 0.51 9.4 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 PRP80437.1 - 0.056 12.8 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TsaE PF02367.17 PRP80437.1 - 0.072 13.1 0.1 0.2 11.7 0.1 1.7 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 PRP80437.1 - 0.12 12.2 0.0 0.38 10.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 PRP80439.1 - 1.1e-23 83.0 18.5 0.00043 21.0 0.1 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3337 PF11816.8 PRP80439.1 - 2.3e-23 82.9 0.2 4.8e-23 81.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) Nucleoporin_N PF08801.11 PRP80439.1 - 0.00016 20.6 1.9 0.1 11.3 0.2 2.7 1 1 1 2 2 2 2 Nup133 N terminal like WD40_like PF17005.5 PRP80439.1 - 0.039 13.3 1.7 1.5 8.0 0.0 2.8 3 1 1 4 4 4 0 WD40-like domain RAWUL PF16207.5 PRP80439.1 - 0.17 12.6 0.1 0.58 10.9 0.0 2.0 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rep_1B PF17873.1 PRP80439.1 - 0.18 11.7 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Replicase polyprotein 1ab TPR_8 PF13181.6 PRP80440.1 - 2.2e-14 52.4 9.6 2.9e-05 23.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 PRP80440.1 - 6.4e-13 48.8 2.6 8.7e-05 22.7 0.0 3.8 2 2 2 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 PRP80440.1 - 3.2e-10 39.3 0.6 0.035 14.1 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP80440.1 - 1.4e-08 34.5 1.6 6e-05 22.6 0.0 2.6 2 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 PRP80440.1 - 9.5e-08 31.6 2.3 0.0012 18.5 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP80440.1 - 1.4e-05 24.9 3.9 0.098 12.8 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4810 PF16068.5 PRP80440.1 - 0.0032 18.0 0.9 0.024 15.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4810) TPR_6 PF13174.6 PRP80440.1 - 0.013 16.1 1.8 2.9 8.7 0.0 4.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP80440.1 - 0.032 14.1 0.1 0.74 9.8 0.0 3.3 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 PRP80440.1 - 0.059 12.8 14.6 0.64 9.4 8.8 2.2 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP DUF3585 PF12130.8 PRP80440.1 - 0.17 12.0 0.7 0.61 10.2 0.6 1.9 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain SMBP PF16785.5 PRP80440.1 - 1.9 8.7 6.4 0.5 10.6 0.4 2.6 3 0 0 3 3 3 0 Small metal-binding protein Adaptin_N PF01602.20 PRP80441.1 - 1.5e-112 376.8 9.9 2.3e-112 376.3 9.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PRP80441.1 - 1.2e-13 51.5 0.4 1e-10 41.9 0.0 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PRP80441.1 - 5.2e-07 30.0 1.0 0.023 15.1 0.0 3.2 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 PRP80441.1 - 0.00069 19.7 5.1 11 6.6 0.1 5.0 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 PRP80441.1 - 0.0035 17.5 0.3 0.75 10.0 0.1 3.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 PRP80441.1 - 0.015 15.9 0.1 1.3 9.7 0.0 3.4 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 PRP80441.1 - 0.52 10.9 2.4 39 4.9 0.2 3.8 2 1 1 3 3 3 0 HEAT-like repeat Pkinase PF00069.25 PRP80442.1 - 1.8e-61 207.8 0.0 2.8e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80442.1 - 5.5e-47 160.2 0.0 1e-46 159.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_3 PF13415.6 PRP80442.1 - 2.6e-14 53.1 8.6 4.5e-09 36.4 0.0 6.0 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 PRP80442.1 - 1.2e-13 50.8 15.4 5.2e-08 32.8 0.1 6.6 6 2 2 8 8 8 2 Galactose oxidase, central domain LSM PF01423.22 PRP80442.1 - 2e-11 43.4 0.6 4.9e-11 42.1 0.3 1.8 2 0 0 2 2 2 1 LSM domain Kelch_5 PF13854.6 PRP80442.1 - 1.2e-10 41.1 6.5 1.1e-06 28.5 0.0 5.5 7 0 0 7 7 7 2 Kelch motif Kelch_6 PF13964.6 PRP80442.1 - 6.2e-10 39.0 6.5 0.0006 20.0 0.0 6.6 5 2 2 7 7 7 2 Kelch motif Kelch_1 PF01344.25 PRP80442.1 - 0.00024 20.6 4.8 1.9 8.1 0.0 5.1 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 PRP80442.1 - 0.00028 20.7 9.3 0.83 9.7 0.0 6.1 6 1 1 7 7 7 2 Kelch motif Pkinase_fungal PF17667.1 PRP80442.1 - 0.00029 19.8 0.1 0.0022 16.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase PBD PF00786.28 PRP80442.1 - 0.038 14.4 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain Kinase-like PF14531.6 PRP80442.1 - 0.13 11.6 0.0 0.54 9.5 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 PRP80443.1 - 3.5e-73 246.2 0.0 4e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80443.1 - 6.3e-30 104.3 0.0 8.7e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP80443.1 - 1e-05 24.7 0.0 0.00026 20.1 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PRP80443.1 - 0.0059 15.7 0.0 0.0095 15.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 PRP80443.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP80443.1 - 0.057 12.7 0.1 2 7.6 0.0 2.3 1 1 0 2 2 2 0 Kinase-like DUF3874 PF12990.7 PRP80445.1 - 0.026 14.9 0.1 0.048 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) MLVIN_C PF18697.1 PRP80445.1 - 0.15 12.1 0.2 0.45 10.6 0.0 1.9 2 1 1 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Fic PF02661.18 PRP80448.1 - 1e-06 29.5 0.1 7.3e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family CSN4_RPN5_eIF3a PF18420.1 PRP80449.1 - 0.00062 19.9 0.0 0.0067 16.6 0.1 2.1 2 0 0 2 2 2 1 CSN4/RPN5/eIF3a helix turn helix domain DUF5344 PF17279.2 PRP80449.1 - 0.029 14.9 0.6 5.2 7.7 0.2 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DUF1251 PF06856.11 PRP80449.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1251) RUN PF02759.19 PRP80450.1 - 5.6e-21 74.9 0.1 5.6e-21 74.9 0.1 2.6 3 0 0 3 3 3 1 RUN domain zf-RING_9 PF13901.6 PRP80450.1 - 1.5e-20 74.1 0.0 1.5e-20 74.1 0.0 3.6 2 1 1 3 3 3 1 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 PRP80450.1 - 2.6 8.0 8.1 1.4 8.9 4.5 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SLATT_fungal PF18142.1 PRP80451.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Tti2 PF10521.9 PRP80455.1 - 0.0037 16.8 1.6 0.0037 16.8 1.6 2.1 3 0 0 3 3 3 1 Tti2 family IF-2B PF01008.17 PRP80457.1 - 2e-73 247.1 0.0 2.3e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family N6-adenineMlase PF10237.9 PRP80458.1 - 8.4e-41 139.4 0.4 9.9e-41 139.2 0.4 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase MTS PF05175.14 PRP80458.1 - 0.051 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Arm PF00514.23 PRP80459.1 - 0.0037 17.3 0.4 1 9.5 0.0 3.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat PQ-loop PF04193.14 PRP80459.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 PQ loop repeat Telomere_reg-2 PF10193.9 PRP80459.1 - 0.04 14.4 0.4 0.87 10.1 0.1 2.9 2 1 1 3 3 3 0 Telomere length regulation protein PRD PF00874.20 PRP80459.1 - 0.06 13.6 0.1 0.62 10.4 0.0 2.6 2 0 0 2 2 2 0 PRD domain PI3_PI4_kinase PF00454.27 PRP80459.1 - 0.086 12.6 6.2 2.5 7.9 0.4 2.5 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase DR2241 PF18069.1 PRP80459.1 - 0.23 11.3 2.7 0.48 10.3 2.7 1.5 1 0 0 1 1 1 0 DR2241 stabilising domain YqzH PF14164.6 PRP80459.1 - 0.27 11.4 1.9 4.3 7.5 0.2 3.2 3 0 0 3 3 3 0 YqzH-like protein RIC3 PF15361.6 PRP80459.1 - 0.45 10.9 6.7 1.2 9.5 6.7 1.7 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Ras PF00071.22 PRP80460.1 - 6.1e-44 149.5 0.0 7.3e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP80460.1 - 1.3e-23 83.5 0.0 1.8e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP80460.1 - 1.3e-12 47.5 0.0 1.8e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP80460.1 - 0.00014 21.9 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP80460.1 - 0.00034 20.2 0.0 0.00069 19.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP80460.1 - 0.0034 16.8 0.0 0.0043 16.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PRP80460.1 - 0.007 16.3 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Ank_2 PF12796.7 PRP80461.1 - 5e-10 39.8 0.0 3.6e-06 27.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP80461.1 - 1.3e-08 35.0 0.3 4.5e-05 23.7 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP80461.1 - 2.5e-07 31.1 0.0 0.44 11.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80461.1 - 5.1e-07 29.5 0.0 0.49 11.1 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat SH2 PF00017.24 PRP80461.1 - 0.00019 21.5 1.9 0.00053 20.0 0.4 2.5 2 0 0 2 2 2 1 SH2 domain Ank PF00023.30 PRP80461.1 - 0.00044 20.6 0.4 0.086 13.3 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeat SAP18 PF06487.12 PRP80461.1 - 3.2 7.9 5.6 1.9 8.7 0.1 3.0 3 0 0 3 3 3 0 Sin3 associated polypeptide p18 (SAP18) Ribosomal_60s PF00428.19 PRP80461.1 - 3.6 8.2 13.2 14 6.4 1.9 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein ThiF PF00899.21 PRP80462.1 - 8.8e-18 64.5 0.0 1.9e-17 63.4 0.0 1.5 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 PRP80462.1 - 1.2e-05 25.4 0.1 0.09 13.0 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle DUF758 PF05527.11 PRP80463.1 - 1.2e-10 41.6 0.1 2.1e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PH PF00169.29 PRP80463.1 - 1.2e-09 38.6 0.1 2.4e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP80463.1 - 0.0004 20.8 0.4 0.0014 19.0 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 PRP80463.1 - 0.11 12.8 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_M8 PF01457.16 PRP80464.1 - 1.3e-92 311.2 3.8 2.6e-92 310.2 3.8 1.4 1 1 0 1 1 1 1 Leishmanolysin Astacin PF01400.24 PRP80464.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) TIG PF01833.24 PRP80464.1 - 0.12 12.4 8.8 0.024 14.7 3.6 2.6 2 1 0 2 2 2 0 IPT/TIG domain TPR_10 PF13374.6 PRP80465.1 - 3.9e-06 26.5 0.6 0.037 13.9 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP80465.1 - 4.2e-06 26.9 5.7 0.6 10.4 0.1 6.0 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP80465.1 - 0.0018 17.7 0.1 1 8.6 0.0 3.1 1 1 0 2 2 2 2 MalT-like TPR region ANAPC3 PF12895.7 PRP80465.1 - 0.0032 17.7 0.1 7.6 6.8 0.4 3.5 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 PRP80465.1 - 0.0041 17.1 5.0 55 4.2 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat SPOB_a PF14689.6 PRP80465.1 - 0.037 13.7 1.2 35 4.2 0.0 3.8 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain HTH_53 PF18606.1 PRP80465.1 - 0.11 12.2 1.5 0.24 11.1 0.5 2.1 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain TPR_1 PF00515.28 PRP80465.1 - 0.23 11.3 6.8 6.5 6.7 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP80465.1 - 1.9 8.9 7.1 64 4.1 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat EF-hand_6 PF13405.6 PRP80466.1 - 3.3e-06 26.6 1.8 1.1 9.3 0.0 6.3 6 0 0 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 PRP80466.1 - 4.8e-06 26.9 12.0 0.028 14.9 0.1 5.3 4 2 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 PRP80466.1 - 1.3e-05 24.3 0.8 0.36 10.5 0.0 5.1 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PRP80466.1 - 0.0015 18.3 1.9 0.086 12.7 0.0 4.0 4 1 0 4 4 4 1 EF-hand domain pair EF-hand_13 PF17958.1 PRP80466.1 - 0.016 15.0 0.0 5.5 6.9 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain EF-hand_9 PF14658.6 PRP80466.1 - 0.027 14.8 0.0 9.8 6.6 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain FBA_2 PF07735.17 PRP80466.1 - 0.035 14.2 3.6 10 6.3 0.2 4.0 4 0 0 4 4 4 0 F-box associated MFS_1 PF07690.16 PRP80468.1 - 1.2e-15 57.3 31.9 1.2e-15 57.3 31.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SprA-related PF12118.8 PRP80470.1 - 0.021 14.0 14.1 0.054 12.6 14.1 1.6 1 0 0 1 1 1 0 SprA-related family DUF16 PF01519.16 PRP80470.1 - 0.16 12.5 12.0 0.41 11.1 12.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 TERB2 PF15101.6 PRP80470.1 - 0.17 11.9 7.9 0.48 10.5 7.9 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FemAB PF02388.16 PRP80470.1 - 0.54 9.1 7.1 0.83 8.5 7.1 1.2 1 0 0 1 1 1 0 FemAB family TFIIA PF03153.13 PRP80470.1 - 1.2 9.1 42.9 1.2 9.0 41.5 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 PRP80470.1 - 1.4 7.8 39.1 2.5 7.0 39.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4407 PF14362.6 PRP80470.1 - 2.2 7.6 7.9 3.7 6.8 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Borrelia_P83 PF05262.11 PRP80470.1 - 4.4 5.7 7.9 6.9 5.0 7.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Synaptobrevin PF00957.21 PRP80471.1 - 3.7e-34 116.4 6.1 6e-34 115.7 6.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PRP80471.1 - 2.7e-25 88.2 0.2 4.6e-25 87.5 0.2 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Corona_S2 PF01601.16 PRP80471.1 - 0.001 17.7 0.1 0.001 17.7 0.1 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein DUF730 PF05325.11 PRP80471.1 - 0.036 14.1 0.8 0.057 13.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF730) Redoxin PF08534.10 PRP80471.1 - 0.066 12.9 0.1 0.091 12.5 0.1 1.2 1 0 0 1 1 1 0 Redoxin S6OS1 PF15676.5 PRP80471.1 - 0.41 9.1 6.3 0.2 10.1 2.8 2.0 2 1 1 3 3 3 0 Six6 opposite strand transcript 1 family YlbE PF14003.6 PRP80471.1 - 0.42 11.1 2.4 0.55 10.7 0.9 2.0 2 0 0 2 2 2 0 YlbE-like protein TraG-D_C PF12696.7 PRP80472.1 - 1.1 9.2 5.3 0.16 12.0 1.4 1.6 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG AhpC-TSA PF00578.21 PRP80473.1 - 4.2e-14 52.5 0.0 4.4e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PRP80473.1 - 2.7e-09 36.9 0.0 2.7e-09 36.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF35_N PF12172.8 PRP80473.1 - 0.086 12.7 1.0 0.13 12.2 1.0 1.2 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) AATase PF07247.12 PRP80475.1 - 2.5e-27 95.6 0.0 2e-26 92.6 0.0 2.2 2 1 0 2 2 2 1 Alcohol acetyltransferase Cyclin_N PF00134.23 PRP80475.1 - 1.8e-25 89.1 0.1 4.6e-25 87.8 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Condensation PF00668.20 PRP80475.1 - 2.3e-09 36.5 0.0 2.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Condensation domain Cyclin_C PF02984.19 PRP80475.1 - 0.028 14.5 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 Cyclin, C-terminal domain WES_acyltransf PF03007.16 PRP80475.1 - 0.032 14.0 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DnaJ_C PF01556.18 PRP80476.1 - 2.2e-29 102.5 1.7 3.6e-29 101.8 1.7 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PRP80476.1 - 3.3e-24 84.8 2.9 5.8e-24 84.0 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain ARID PF01388.21 PRP80478.1 - 0.019 15.6 0.1 0.026 15.2 0.1 1.1 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain Pkinase_fungal PF17667.1 PRP80479.1 - 1.6e-07 30.5 0.1 0.00064 18.6 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase RIO1 PF01163.22 PRP80479.1 - 0.042 13.4 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family UCH PF00443.29 PRP80481.1 - 2.9e-45 154.8 1.3 7.1e-45 153.5 1.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP80481.1 - 1.5e-15 57.6 9.2 1.3e-14 54.6 3.7 3.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PRP80481.1 - 1.1e-12 48.4 15.7 3.1e-05 24.5 0.1 5.6 5 1 0 5 5 5 3 DUSP domain ubiquitin PF00240.23 PRP80481.1 - 1.3e-11 44.1 0.3 3.8e-11 42.6 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin family zf-RanBP PF00641.18 PRP80481.1 - 6.1e-06 25.5 1.3 6.1e-06 25.5 1.3 3.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF2757 PF10955.8 PRP80481.1 - 0.019 15.2 3.3 0.37 11.1 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2757) TBK1_ULD PF18396.1 PRP80481.1 - 0.15 12.0 0.2 0.37 10.7 0.2 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP80481.1 - 0.9 9.9 5.9 23 5.4 1.0 3.4 3 0 0 3 3 3 0 Ubiquitin-like domain Metallophos PF00149.28 PRP80484.1 - 8.8e-24 85.1 2.1 1.4e-23 84.5 2.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PRP80484.1 - 7.1e-17 62.0 1.5 2.2e-16 60.4 0.5 2.5 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 PRP80484.1 - 1.2e-05 25.8 1.0 3.5e-05 24.3 1.0 1.8 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 PRP80484.1 - 0.00013 22.2 0.1 0.00052 20.2 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HCO3_cotransp PF00955.21 PRP80485.1 - 1.2e-75 255.3 7.0 8.1e-42 143.7 3.5 3.0 1 1 1 2 2 2 2 HCO3- transporter family ubiquitin PF00240.23 PRP80486.1 - 7.1e-18 64.1 0.0 1.5e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP80486.1 - 1.1e-07 31.5 0.0 2.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like SH2 PF00017.24 PRP80486.1 - 1.3e-06 28.4 0.0 3.3e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Ubiquitin_2 PF14560.6 PRP80486.1 - 0.078 13.4 0.0 0.26 11.8 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain FGase PF05013.12 PRP80486.1 - 0.17 12.1 0.2 0.31 11.2 0.2 1.5 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase PPR_2 PF13041.6 PRP80487.1 - 8.3e-11 41.9 0.1 2.1e-07 31.0 0.0 3.2 2 1 2 4 4 4 2 PPR repeat family PPR_3 PF13812.6 PRP80487.1 - 1.8e-09 37.5 0.0 0.00017 21.6 0.0 3.5 3 1 2 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 PRP80487.1 - 0.0015 18.6 0.0 24 5.5 0.0 4.5 5 0 0 5 5 5 0 PPR repeat PPR_1 PF12854.7 PRP80487.1 - 0.0047 16.6 0.0 1.9 8.3 0.0 2.9 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 PRP80487.1 - 0.0048 16.3 0.1 0.015 14.6 0.1 1.9 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP KfrA_N PF11740.8 PRP80487.1 - 0.029 15.0 0.5 4 8.1 0.0 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Exog_C PF18026.1 PRP80487.1 - 0.24 11.5 5.0 9.9 6.3 0.1 4.1 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain REV1_C PF16727.5 PRP80487.1 - 0.25 11.7 2.2 1.1 9.7 2.2 2.1 1 1 0 1 1 1 0 DNA repair protein REV1 C-terminal domain Arf PF00025.21 PRP80488.1 - 4.5e-62 208.6 0.4 5.7e-62 208.3 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PRP80488.1 - 6.2e-14 52.2 0.6 9.2e-14 51.7 0.6 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP80488.1 - 4.9e-12 45.8 0.2 5.8e-12 45.5 0.2 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PRP80488.1 - 3.2e-10 39.7 0.1 4.3e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PRP80488.1 - 1.6e-07 31.4 0.3 2.2e-07 30.9 0.3 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PRP80488.1 - 1e-06 28.2 0.5 1e-05 24.9 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 PRP80488.1 - 1.3e-05 24.7 0.3 1.6e-05 24.4 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 PRP80488.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 PRP80488.1 - 0.028 14.2 0.0 0.79 9.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PRP80488.1 - 0.029 14.9 0.2 0.066 13.7 0.2 1.6 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 PRP80488.1 - 0.06 13.4 0.2 3.5 7.6 0.1 2.1 2 0 0 2 2 2 0 Dynamin family AAA_21 PF13304.6 PRP80488.1 - 0.064 13.1 0.1 0.086 12.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PRP80488.1 - 0.079 13.5 0.5 0.16 12.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PRP80488.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PRP80488.1 - 0.22 11.1 1.7 12 5.4 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 PRP80488.1 - 0.8 9.2 3.4 2.7 7.5 0.5 2.1 1 1 1 2 2 2 0 Ferrous iron transport protein B Ank_2 PF12796.7 PRP80489.1 - 1.5e-43 147.2 0.0 2.5e-11 44.0 0.0 4.8 2 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80489.1 - 5.5e-38 128.9 1.6 1.9e-07 31.5 0.0 8.8 3 2 9 12 12 12 8 Ankyrin repeats (many copies) Peptidase_S8 PF00082.22 PRP80489.1 - 2.4e-32 112.4 12.9 8.3e-28 97.5 2.6 2.6 1 1 1 2 2 2 2 Subtilase family Ank_5 PF13857.6 PRP80489.1 - 8e-26 89.8 0.0 0.022 15.1 0.0 11.0 2 1 9 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 PRP80489.1 - 3.5e-21 74.6 6.5 0.26 11.8 0.1 10.7 9 1 0 9 9 9 4 Ankyrin repeat Ank_3 PF13606.6 PRP80489.1 - 1.3e-13 49.8 0.3 13 6.8 0.0 9.8 9 0 0 9 9 9 3 Ankyrin repeat Inhibitor_I9 PF05922.16 PRP80489.1 - 4.9e-07 30.3 0.3 2.2e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase inhibitor I9 DUF4671 PF15710.5 PRP80489.1 - 0.011 14.6 5.4 0.12 11.2 2.6 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4671) VWA_3_C PF18571.1 PRP80489.1 - 0.2 11.6 6.5 76 3.3 0.0 6.3 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain SH2 PF00017.24 PRP80490.1 - 2.8e-25 88.2 1.3 2.9e-12 46.5 0.0 4.2 4 0 0 4 4 4 2 SH2 domain Cbl_N2 PF02761.14 PRP80490.1 - 1.4e-09 38.5 0.0 3.8e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain DEP PF00610.21 PRP80490.1 - 0.0019 18.2 0.0 0.01 15.9 0.0 2.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cbl_N3 PF02762.14 PRP80490.1 - 0.0077 16.1 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, SH2-like domain IBP39 PF11422.8 PRP80490.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 Initiator binding protein 39 kDa NDUF_B6 PF09782.9 PRP80490.1 - 0.035 14.2 0.2 0.64 10.1 0.0 2.6 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit LVIVD PF08309.11 PRP80490.1 - 0.14 11.5 0.0 0.38 10.1 0.0 1.6 1 0 0 1 1 1 0 LVIVD repeat Glyco_hydro_16 PF00722.21 PRP80491.1 - 1.1e-06 28.3 0.0 1.9e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Carb_bind PF10645.9 PRP80491.1 - 0.014 15.6 1.7 0.014 15.6 1.7 3.1 4 0 0 4 4 4 0 Carbohydrate binding Defensin_beta PF00711.19 PRP80491.1 - 3.1 7.9 6.5 25 5.0 1.4 3.2 2 0 0 2 2 2 0 Beta defensin E1-E2_ATPase PF00122.20 PRP80492.1 - 8.8e-42 142.7 2.6 8.8e-42 142.7 2.6 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PRP80492.1 - 3.5e-38 131.1 7.0 3.5e-38 131.1 7.0 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PRP80492.1 - 1.3e-23 84.4 0.5 3.6e-21 76.4 0.5 3.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP80492.1 - 1.7e-15 56.9 0.0 5.3e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) GST_C PF00043.25 PRP80492.1 - 3.4e-13 49.6 0.0 9.2e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP80492.1 - 9.1e-11 42.0 0.0 8.1e-10 38.9 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP80492.1 - 1.4e-10 41.0 0.8 3.4e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP80492.1 - 3.6e-10 40.1 0.0 1.8e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP80492.1 - 3.6e-10 39.9 0.1 1.1e-09 38.3 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cation_ATPase_N PF00690.26 PRP80492.1 - 3.8e-09 36.1 0.9 8.6e-09 35.0 0.0 2.2 2 0 0 2 2 1 1 Cation transporter/ATPase, N-terminus GST_N_2 PF13409.6 PRP80492.1 - 2.4e-08 34.2 0.0 5.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Hydrolase_3 PF08282.12 PRP80492.1 - 1.9e-06 27.8 0.1 0.00044 20.1 0.0 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CLU PF13236.6 PRP80494.1 - 1.8e-42 145.7 0.0 4e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP80494.1 - 0.0011 19.0 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Caps_synth PF05704.12 PRP80496.1 - 3.2e-12 46.4 0.0 5.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 PRP80496.1 - 7.4e-05 23.3 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif COX6B PF02297.17 PRP80497.1 - 1.4e-14 54.1 3.6 1.7e-14 53.8 3.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 PRP80497.1 - 0.00065 19.8 1.5 0.0013 18.8 1.5 1.5 1 0 0 1 1 1 1 CHCH domain RFC1 PF08519.12 PRP80497.1 - 0.092 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain CX9C PF16860.5 PRP80497.1 - 0.16 12.0 1.8 0.27 11.3 1.8 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Sec2p PF06428.11 PRP80498.1 - 7.5e-08 32.2 9.4 7.5e-08 32.2 9.4 2.7 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p EMP24_GP25L PF01105.24 PRP80498.1 - 0.24 11.3 1.9 0.49 10.3 1.3 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4201 PF13870.6 PRP80498.1 - 0.27 11.0 8.5 0.039 13.7 4.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DivIVA PF05103.13 PRP80498.1 - 0.84 9.7 7.4 1.5 8.9 7.4 1.3 1 0 0 1 1 1 0 DivIVA protein Ribosomal_L29 PF00831.23 PRP80498.1 - 1.1 9.3 10.1 14 5.7 2.7 3.4 2 1 1 3 3 3 0 Ribosomal L29 protein Ank_4 PF13637.6 PRP80499.1 - 9.4e-09 35.7 3.1 0.49 11.0 0.0 6.9 8 2 1 9 9 9 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP80499.1 - 0.0001 22.8 0.0 1.7 9.3 0.0 4.5 4 1 1 5 5 5 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP80499.1 - 0.0011 19.3 0.0 23 5.4 0.0 4.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80499.1 - 0.0014 19.0 0.1 48 5.0 0.0 6.5 7 0 0 7 7 7 0 Ankyrin repeat DUF4014 PF13198.6 PRP80499.1 - 0.17 12.3 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) Pkinase_Tyr PF07714.17 PRP80501.1 - 2.2e-56 191.0 0.0 3.3e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80501.1 - 5.9e-43 147.1 0.0 1.1e-42 146.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 PRP80501.1 - 8.6e-36 123.6 0.0 2.1e-35 122.3 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain LRR_6 PF13516.6 PRP80501.1 - 3.4e-24 82.8 50.2 0.00084 19.2 0.2 14.9 15 0 0 15 15 15 8 Leucine Rich repeat Roc PF08477.13 PRP80501.1 - 3.1e-23 82.3 0.0 8.3e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 PRP80501.1 - 2.2e-14 53.0 40.3 2.6e-06 27.1 10.3 9.0 6 3 2 8 8 8 4 Leucine rich repeat Ras PF00071.22 PRP80501.1 - 4e-11 42.8 0.3 7.5e-11 41.9 0.3 1.4 1 0 0 1 1 1 1 Ras family LRR_4 PF12799.7 PRP80501.1 - 2.1e-07 31.1 51.9 0.00041 20.7 8.5 9.1 5 3 4 10 10 9 5 Leucine Rich repeats (2 copies) Arf PF00025.21 PRP80501.1 - 5.8e-05 22.6 0.2 0.00015 21.3 0.2 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP80501.1 - 7.8e-05 22.7 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase LRR_1 PF00560.33 PRP80501.1 - 0.0013 19.0 33.6 8.5 7.4 0.2 12.0 12 1 0 12 12 11 1 Leucine Rich Repeat FeoB_N PF02421.18 PRP80501.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 PRP80501.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Septin Gtr1_RagA PF04670.12 PRP80501.1 - 0.074 12.4 0.2 0.18 11.1 0.2 1.7 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 PRP80501.1 - 0.083 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Pkinase_fungal PF17667.1 PRP80501.1 - 0.17 10.6 0.0 0.37 9.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SWIM PF04434.17 PRP80502.1 - 0.027 14.1 0.2 0.06 13.0 0.2 1.6 1 0 0 1 1 1 0 SWIM zinc finger Pkinase_Tyr PF07714.17 PRP80503.1 - 2.7e-11 43.3 0.1 4.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP80503.1 - 0.0019 17.6 0.0 0.038 13.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain DUF3300 PF11737.8 PRP80503.1 - 0.091 12.3 0.7 1.6 8.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3300) Pkinase_Tyr PF07714.17 PRP80504.1 - 1.6e-18 66.9 0.2 8e-16 58.1 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 PRP80504.1 - 2.3e-16 59.3 29.1 1.4e-05 24.7 2.8 5.5 4 1 0 5 5 5 4 Leucine rich repeat Pkinase PF00069.25 PRP80504.1 - 3e-10 39.9 0.1 3.4e-08 33.2 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain GPS PF01825.21 PRP80504.1 - 9e-08 32.5 1.1 1.8e-07 31.5 1.1 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP80504.1 - 3e-07 30.7 35.8 0.0051 17.2 3.1 7.0 2 1 6 8 8 8 7 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP80504.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_1 PF00560.33 PRP80504.1 - 0.015 15.7 34.4 6.1 7.8 0.5 9.3 9 1 0 9 9 9 0 Leucine Rich Repeat SET PF00856.28 PRP80505.1 - 9.1e-14 52.2 0.2 2.3e-13 50.9 0.2 1.8 1 0 0 1 1 1 1 SET domain FYVE_2 PF02318.16 PRP80505.1 - 0.00033 20.9 6.5 0.00092 19.4 6.5 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger MULE PF10551.9 PRP80505.1 - 0.0018 18.7 0.0 0.0046 17.4 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain IBR PF01485.21 PRP80505.1 - 1.1 9.6 8.9 1.1 9.5 7.0 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 PRP80505.1 - 1.3 9.3 12.7 3.6 7.8 12.7 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_2 PF13639.6 PRP80505.1 - 6.6 7.2 10.2 16 5.9 10.2 1.7 1 0 0 1 1 1 0 Ring finger domain Ank_2 PF12796.7 PRP80506.1 - 1.9e-39 134.1 1.6 5e-11 43.0 0.0 4.7 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80506.1 - 3.8e-25 87.9 9.2 8.2e-06 26.3 0.0 6.3 2 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP80506.1 - 1.6e-21 75.7 4.4 0.15 12.5 0.0 8.7 5 3 3 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 PRP80506.1 - 3.2e-21 75.1 1.6 0.013 15.8 0.0 7.5 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80506.1 - 4.4e-17 60.4 4.0 0.21 12.2 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeat Anthrax_toxA PF03497.16 PRP80506.1 - 4.7e-06 26.9 0.6 1.3 9.1 0.1 4.2 1 1 2 4 4 4 2 Anthrax toxin LF subunit YlzJ PF14035.6 PRP80506.1 - 1.7e-05 24.9 1.4 1.2 9.4 0.0 5.6 6 1 1 7 7 7 2 YlzJ-like protein INTS5_C PF14838.6 PRP80506.1 - 0.055 12.1 1.1 1.5 7.3 0.2 2.7 3 0 0 3 3 3 0 Integrator complex subunit 5 C-terminus Pkinase_Tyr PF07714.17 PRP80507.1 - 3.4e-26 92.1 4.8 2.2e-24 86.1 0.6 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP80507.1 - 6.7e-18 65.0 0.5 6.7e-18 65.0 0.5 2.1 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 PRP80507.1 - 2.6e-13 49.5 40.1 7.7e-06 25.6 4.9 4.2 3 1 1 4 4 4 4 Leucine rich repeat GPS PF01825.21 PRP80507.1 - 4.1e-10 40.0 5.1 1.2e-09 38.5 5.1 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP80507.1 - 5.9e-10 39.2 39.3 0.00063 20.1 7.4 5.8 5 0 0 5 5 5 5 Leucine Rich repeats (2 copies) Med31 PF05669.12 PRP80507.1 - 9e-06 25.6 10.6 0.004 17.1 0.8 3.3 2 1 1 3 3 3 2 SOH1 TMEM154 PF15102.6 PRP80507.1 - 0.017 15.0 1.3 0.022 14.7 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family Syndecan PF01034.20 PRP80507.1 - 0.044 13.7 0.6 0.096 12.6 0.6 1.5 1 0 0 1 1 1 0 Syndecan domain Bromodomain PF00439.25 PRP80508.1 - 3.5e-22 78.3 0.2 6.4e-22 77.4 0.2 1.5 1 0 0 1 1 1 1 Bromodomain WSD PF15613.6 PRP80508.1 - 0.016 15.7 0.4 0.034 14.6 0.4 1.7 1 0 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF218 PF02698.17 PRP80510.1 - 3.5e-16 59.4 0.0 4.3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain TPR_12 PF13424.6 PRP80511.1 - 1.9e-26 92.1 10.3 3.2e-06 27.3 0.0 7.4 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 PRP80511.1 - 5.1e-22 76.2 14.1 0.013 15.5 0.0 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 PRP80511.1 - 6.9e-22 76.3 9.6 0.0056 16.4 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 PRP80511.1 - 6.3e-17 60.3 1.8 0.051 13.6 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 PRP80511.1 - 7.9e-15 53.8 11.6 0.00081 19.4 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat NB-ARC PF00931.22 PRP80511.1 - 6.9e-11 41.8 0.2 2e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_14 PF13428.6 PRP80511.1 - 5.7e-09 36.0 6.6 0.9 10.5 0.2 8.0 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP80511.1 - 3.2e-08 33.2 12.9 0.11 12.4 0.1 7.2 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP80511.1 - 8.8e-08 32.3 7.0 6.7 7.6 0.0 8.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP80511.1 - 1.5e-07 31.9 0.0 2.8 8.7 0.0 6.0 4 1 1 6 6 5 2 Tetratricopeptide repeat NACHT PF05729.12 PRP80511.1 - 5.4e-06 26.4 0.0 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 PRP80511.1 - 8.8e-06 26.2 2.9 0.093 13.3 0.0 5.6 3 2 3 6 6 6 1 Tetratricopeptide repeat ATPase_2 PF01637.18 PRP80511.1 - 2.2e-05 24.5 4.1 0.019 14.9 0.0 3.4 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea SNAP PF14938.6 PRP80511.1 - 3.3e-05 23.5 9.8 0.13 11.7 1.3 3.9 3 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP AAA_14 PF13173.6 PRP80511.1 - 0.0019 18.2 0.1 0.01 15.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain TPR_17 PF13431.6 PRP80511.1 - 0.0034 17.7 0.3 34 5.1 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_19 PF13245.6 PRP80511.1 - 0.017 15.5 0.1 2.4 8.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.6 PRP80511.1 - 0.022 14.4 1.2 1.1e+02 2.6 0.0 5.5 6 0 0 6 6 6 0 TPR repeat AAA_16 PF13191.6 PRP80511.1 - 0.027 14.8 0.0 0.29 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain RPN7 PF10602.9 PRP80511.1 - 0.1 12.3 8.5 0.45 10.2 0.6 4.3 2 2 2 4 4 4 0 26S proteasome subunit RPN7 ANAPC5 PF12862.7 PRP80511.1 - 0.22 11.6 5.8 10 6.3 0.0 4.9 3 2 3 6 6 5 0 Anaphase-promoting complex subunit 5 PPR PF01535.20 PRP80511.1 - 1 9.8 4.8 30 5.1 0.0 4.3 4 0 0 4 4 3 0 PPR repeat Phage_holin_6_1 PF09682.10 PRP80511.1 - 1.9 8.9 4.3 2 8.9 0.4 2.9 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Mito_carr PF00153.27 PRP80512.1 - 3.2e-60 200.1 0.1 1.2e-20 73.3 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 PRP80512.1 - 4.2e-18 65.4 33.2 2.9e-11 42.9 10.6 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.13 PRP80512.1 - 3.7e-13 49.6 1.2 8.2e-13 48.4 1.2 1.6 1 0 0 1 1 1 1 Nodulin-like RabGAP-TBC PF00566.18 PRP80514.1 - 2.5e-44 151.5 0.7 6.3e-44 150.2 0.7 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RCC1 PF00415.18 PRP80514.1 - 2e-38 130.7 12.0 4.8e-10 39.9 0.0 8.7 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP80514.1 - 6.2e-22 76.9 20.8 3.2e-07 30.0 0.0 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat GRAM PF02893.20 PRP80514.1 - 2.1e-06 27.6 0.2 0.094 12.6 0.1 2.7 2 0 0 2 2 2 2 GRAM domain TRAPP PF04051.16 PRP80515.1 - 2.7e-12 46.6 0.0 3.2e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Gemini_C4 PF01492.17 PRP80515.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Geminivirus C4 protein F-box_4 PF15966.5 PRP80515.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 F-box TRAPP PF04051.16 PRP80516.1 - 1e-14 54.5 0.0 2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component APG17 PF04108.12 PRP80517.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 GFO_IDH_MocA PF01408.22 PRP80518.1 - 1.1e-14 55.3 0.0 1.8e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF2236 PF09995.9 PRP80519.1 - 5.4e-31 108.5 0.2 7.7e-31 108.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) CNH PF00780.22 PRP80520.1 - 0.066 12.8 0.3 12 5.4 0.0 2.9 3 1 0 3 3 3 0 CNH domain BBS1 PF14779.6 PRP80520.1 - 0.066 12.6 0.4 0.54 9.7 0.1 2.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 1 MFS_1 PF07690.16 PRP80521.1 - 1.4e-30 106.4 30.6 4.2e-19 68.7 18.6 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP80521.1 - 5.2e-27 94.8 20.6 1e-25 90.5 20.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Methyltransf_16 PF10294.9 PRP80522.1 - 2.6e-34 118.5 0.1 4e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 PRP80522.1 - 8.1e-05 22.2 0.0 8.1e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PRP80522.1 - 0.00053 20.6 0.0 0.0012 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP80522.1 - 0.001 18.9 0.1 0.0027 17.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP80522.1 - 0.0012 18.4 0.1 0.0021 17.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PRP80522.1 - 0.0023 17.7 0.1 0.0023 17.7 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP80522.1 - 0.0038 18.0 0.0 0.0038 18.0 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 PRP80522.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_11 PF08241.12 PRP80522.1 - 0.022 15.4 0.0 0.07 13.8 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Borrelia_P83 PF05262.11 PRP80522.1 - 0.14 10.7 26.6 0.17 10.4 26.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2052 PF09747.9 PRP80522.1 - 2.3 8.3 25.9 4.8 7.3 25.9 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) E1_DerP2_DerF2 PF02221.15 PRP80523.1 - 8.4e-14 52.1 0.0 1.3e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 ML domain SNARE_assoc PF09335.11 PRP80523.1 - 5.2e-12 46.3 10.0 5.2e-12 46.3 10.0 2.8 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF2976 PF11190.8 PRP80523.1 - 0.38 10.6 2.3 6.1 6.7 1.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) Acetyltransf_6 PF13480.7 PRP80524.1 - 3.2e-06 27.4 1.7 2.3e-05 24.6 1.7 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP80524.1 - 5e-06 26.7 0.0 9.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 PRP80524.1 - 0.00012 22.1 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy_2 PF13532.6 PRP80524.1 - 0.038 14.2 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Acetyltransf_10 PF13673.7 PRP80524.1 - 0.044 13.7 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4131 PF13567.6 PRP80524.1 - 9.5 5.8 8.0 0.99 9.0 0.4 3.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Actin PF00022.19 PRP80525.1 - 1e-126 422.8 0.0 5e-126 420.6 0.0 1.7 1 1 0 1 1 1 1 Actin zf-ribbon_3 PF13248.6 PRP80526.1 - 0.17 11.3 0.2 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Dus PF01207.17 PRP80527.1 - 7.3e-50 169.8 1.1 1.1e-49 169.3 1.1 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PHTB1_N PF14727.6 PRP80528.1 - 1.3e-140 469.4 0.0 1.9e-140 468.9 0.0 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 PRP80528.1 - 7.1e-75 252.4 3.3 1.2e-74 251.7 3.3 1.4 1 0 0 1 1 1 1 PTHB1 C-terminus EH_Signature PF15611.6 PRP80528.1 - 0.0018 17.8 0.2 0.0032 17.0 0.2 1.4 1 0 0 1 1 1 1 EH_Signature domain Syndecan PF01034.20 PRP80529.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Pkinase_Tyr PF07714.17 PRP80530.1 - 1.7e-47 161.9 0.0 2.1e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80530.1 - 1.7e-27 96.5 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain TMEM154 PF15102.6 PRP80530.1 - 0.00059 19.8 0.1 0.00097 19.1 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 PRP80530.1 - 0.0047 17.8 0.2 0.0099 16.7 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 PRP80530.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF4051 PF13260.6 PRP80530.1 - 0.017 14.8 0.2 0.035 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Herpes_gE PF02480.16 PRP80530.1 - 0.023 13.5 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3377 PF11857.8 PRP80530.1 - 0.023 14.6 0.2 0.061 13.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Pilin_N PF07790.11 PRP80530.1 - 0.027 15.4 1.2 0.52 11.3 1.4 2.4 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal RIFIN PF02009.16 PRP80530.1 - 0.032 14.1 0.2 0.052 13.4 0.2 1.3 1 0 0 1 1 1 0 Rifin LST1 PF05083.13 PRP80530.1 - 0.044 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 LST-1 protein DUF3827 PF12877.7 PRP80530.1 - 0.065 11.6 0.1 0.42 8.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) PRIMA1 PF16101.5 PRP80530.1 - 0.086 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DAG1 PF05454.11 PRP80530.1 - 0.18 11.1 0.1 0.27 10.6 0.1 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Amnionless PF14828.6 PRP80530.1 - 0.19 10.5 0.2 0.27 10.0 0.2 1.1 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 PRP80530.1 - 0.2 11.2 0.1 0.39 10.2 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Insulin_TMD PF17870.1 PRP80530.1 - 7.1 6.8 8.6 16 5.6 8.2 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 PRP80532.1 - 8e-24 84.4 0.0 6.7e-23 81.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80532.1 - 6e-14 51.9 0.0 1.7e-09 37.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP80532.1 - 1.4e-07 30.6 0.2 2.2e-07 30.0 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase F-box-like PF12937.7 PRP80532.1 - 2.4e-07 30.6 0.4 4.5e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP80532.1 - 7.8e-06 25.6 0.9 1.6e-05 24.6 0.9 1.5 1 0 0 1 1 1 1 F-box domain Kdo PF06293.14 PRP80532.1 - 0.00062 19.2 0.3 0.0022 17.4 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP80532.1 - 0.0057 16.6 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family T6SS_HCP PF05638.12 PRP80532.1 - 0.0093 16.4 0.1 0.018 15.5 0.1 1.5 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp ABC1 PF03109.16 PRP80532.1 - 0.041 14.0 0.0 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 ABC1 family Mito_carr PF00153.27 PRP80533.1 - 4.3e-59 196.4 2.3 1.7e-19 69.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RCC1 PF00415.18 PRP80534.1 - 2.6e-79 261.7 22.0 3e-15 56.6 0.3 8.4 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP80534.1 - 1.4e-42 142.6 26.0 4.6e-07 29.5 0.1 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 PRP80534.1 - 1.8e-39 134.4 0.0 3.7e-19 69.0 0.1 3.2 2 1 1 3 3 3 3 BTB/POZ domain DUF1160 PF06648.11 PRP80534.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) CTD_bind PF04818.13 PRP80536.1 - 3.4e-16 59.8 3.7 9.9e-16 58.3 0.2 3.0 4 0 0 4 4 4 1 RNA polymerase II-binding domain. CTK3 PF12243.8 PRP80536.1 - 0.0088 16.0 1.4 0.018 15.0 1.4 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Chorismate_bind PF00425.18 PRP80536.1 - 0.22 11.0 3.6 0.76 9.3 3.6 1.8 1 1 0 1 1 1 0 chorismate binding enzyme CAMSAP_CC1 PF17095.5 PRP80536.1 - 0.81 9.6 6.6 0.81 9.6 2.1 2.4 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Dynactin_p22 PF07426.11 PRP80536.1 - 0.93 9.3 9.6 0.059 13.2 1.4 2.6 2 1 0 2 2 2 0 Dynactin subunit p22 RasGAP PF00616.19 PRP80537.1 - 4.8e-24 85.2 0.4 2.3e-20 73.2 0.2 4.4 3 2 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase ABC_tran PF00005.27 PRP80538.1 - 1.1e-32 113.4 0.0 1.1e-15 58.4 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 PRP80538.1 - 2.9e-11 43.0 6.1 7.1e-11 41.8 6.1 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 PRP80538.1 - 5e-09 35.9 6.2 0.0018 17.7 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 PRP80538.1 - 8.1e-08 31.8 3.3 8.1e-08 31.8 3.3 2.1 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_21 PF13304.6 PRP80538.1 - 1.2e-07 31.9 3.9 0.21 11.4 0.0 4.4 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 PRP80538.1 - 1.3e-06 28.5 0.4 0.12 12.3 0.1 3.3 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_16 PF13191.6 PRP80538.1 - 1.1e-05 25.9 0.0 0.13 12.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 PRP80538.1 - 1.8e-05 24.7 1.4 0.36 10.5 0.3 3.5 3 1 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 PRP80538.1 - 1.9e-05 25.1 0.0 0.3 11.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PRP80538.1 - 4.4e-05 23.5 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 PRP80538.1 - 4.9e-05 23.2 1.8 4.9e-05 23.2 1.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain NACHT PF05729.12 PRP80538.1 - 8.9e-05 22.5 0.2 0.058 13.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 PRP80538.1 - 0.00013 22.2 0.0 0.095 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP80538.1 - 0.00028 21.2 0.1 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_29 PF13555.6 PRP80538.1 - 0.0003 20.5 0.2 0.94 9.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.22 PRP80538.1 - 0.00058 19.5 3.0 0.23 11.0 0.1 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.6 PRP80538.1 - 0.00062 20.3 1.1 0.049 14.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 PRP80538.1 - 0.0019 18.7 1.3 0.0019 18.7 1.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_24 PF13479.6 PRP80538.1 - 0.0021 17.8 0.3 0.45 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 PRP80538.1 - 0.0026 17.8 0.8 0.0026 17.8 0.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 PRP80538.1 - 0.0026 17.8 11.2 0.006 16.7 11.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain TsaE PF02367.17 PRP80538.1 - 0.0028 17.7 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_9 PF13187.6 PRP80538.1 - 0.004 17.3 11.9 0.0082 16.3 11.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_30 PF13604.6 PRP80538.1 - 0.005 16.6 0.6 1.9 8.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 PRP80538.1 - 0.005 16.9 2.5 0.005 16.9 2.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.6 PRP80538.1 - 0.0062 16.7 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PRP80538.1 - 0.01 16.1 0.2 4 7.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PRP80538.1 - 0.013 15.4 0.8 2.6 7.9 0.0 3.3 4 0 0 4 4 2 0 NTPase AAA_18 PF13238.6 PRP80538.1 - 0.015 15.9 0.0 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PRP80538.1 - 0.015 15.4 0.0 7.8 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 PRP80538.1 - 0.021 15.7 1.0 0.021 15.7 1.0 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_5 PF07728.14 PRP80538.1 - 0.024 14.6 0.1 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 PRP80538.1 - 0.025 14.3 0.1 5.5 6.6 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Septin PF00735.18 PRP80538.1 - 0.031 13.6 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 PRP80538.1 - 0.032 13.8 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region CLP1_P PF16575.5 PRP80538.1 - 0.064 13.0 0.4 2 8.1 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Roc PF08477.13 PRP80538.1 - 0.065 13.4 0.5 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 PRP80538.1 - 0.089 12.1 0.1 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 PRP80538.1 - 0.093 11.9 0.1 2.6 7.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TniB PF05621.11 PRP80538.1 - 0.1 12.0 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 PRP80538.1 - 0.11 12.6 2.0 11 6.1 0.3 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.13 PRP80538.1 - 0.17 11.0 0.1 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Pmp3 PF01679.17 PRP80539.1 - 2.7e-12 46.7 3.4 3.4e-12 46.4 3.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator cNMP_binding PF00027.29 PRP80540.1 - 4.4e-22 78.0 0.0 1.2e-09 38.1 0.0 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain 3-HAO PF06052.12 PRP80541.1 - 1.1e-57 193.9 0.0 1.3e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 PRP80541.1 - 1.3e-05 24.8 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 PRP80541.1 - 0.0022 17.6 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 PRP80541.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 PRP80541.1 - 0.017 15.3 0.1 0.032 14.4 0.0 1.5 2 0 0 2 2 2 0 ARD/ARD' family zf-ribbon_3 PF13248.6 PRP80541.1 - 0.15 11.5 1.6 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 PRP80541.1 - 0.6 10.2 4.6 0.97 9.6 0.1 2.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain WD40 PF00400.32 PRP80542.1 - 1.5e-28 98.5 15.0 3.4e-06 27.7 0.9 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80542.1 - 4e-22 78.3 0.4 4.9e-05 23.6 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP80542.1 - 8.9e-09 35.5 0.2 0.00067 19.6 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PRP80542.1 - 4.4e-05 22.3 0.5 0.00041 19.1 0.2 2.2 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 PRP80542.1 - 0.0011 17.6 0.0 0.011 14.3 0.0 2.1 1 1 0 2 2 2 1 Cytochrome D1 heme domain HPS3_N PF14761.6 PRP80542.1 - 0.0023 17.5 0.0 0.28 10.7 0.0 3.0 1 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 Coatomer_WDAD PF04053.14 PRP80542.1 - 0.0067 15.5 0.0 3.6 6.5 0.0 2.4 2 1 1 3 3 3 3 Coatomer WD associated region WD40_like PF17005.5 PRP80542.1 - 0.011 15.1 0.2 2.6 7.3 0.0 3.0 3 2 1 4 4 4 0 WD40-like domain VID27 PF08553.10 PRP80542.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain CNH PF00780.22 PRP80542.1 - 0.081 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 CNH domain DLIC PF05783.11 PRP80543.1 - 1.7e-15 56.8 6.0 3.8e-14 52.4 0.1 3.0 2 1 1 3 3 3 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 PRP80543.1 - 9e-08 32.4 0.2 4.3e-07 30.2 0.0 2.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PRP80543.1 - 0.0048 17.0 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 PRP80543.1 - 0.015 14.9 0.0 0.11 12.1 0.0 2.3 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 PRP80543.1 - 0.019 15.3 0.0 0.22 11.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 PRP80543.1 - 0.034 13.3 1.0 0.059 12.5 0.0 2.1 2 1 0 2 2 2 0 G-protein alpha subunit GTP_EFTU PF00009.27 PRP80543.1 - 0.04 13.5 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP80543.1 - 0.047 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA PF00004.29 PRP80543.1 - 0.079 13.4 0.1 0.36 11.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 PRP80543.1 - 0.37 10.7 2.0 0.9 9.4 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea SurE PF01975.17 PRP80544.1 - 2.5e-53 180.7 0.0 3e-53 180.5 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.6 PRP80544.1 - 0.11 12.9 0.1 0.17 12.4 0.1 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 PRP80544.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like Zn_clus PF00172.18 PRP80545.1 - 0.0032 17.5 18.6 0.0053 16.8 18.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.11 PRP80545.1 - 0.22 9.8 7.1 0.31 9.3 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SRP40_C PF05022.12 PRP80546.1 - 1.9e-24 86.3 2.4 1.9e-24 86.3 2.4 6.5 3 1 0 3 3 3 1 SRP40, C-terminal domain Ank_2 PF12796.7 PRP80547.1 - 2.7e-05 24.7 0.2 0.15 12.6 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP80547.1 - 0.00052 20.3 2.3 39 5.3 0.0 6.6 7 1 0 7 7 7 0 Ankyrin repeat Ank_4 PF13637.6 PRP80547.1 - 0.0043 17.6 3.1 6.6 7.4 0.0 5.7 5 1 2 7 7 7 2 Ankyrin repeats (many copies) F-box PF00646.33 PRP80547.1 - 0.03 14.2 0.3 0.1 12.5 0.3 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 PRP80547.1 - 0.096 12.6 0.4 0.2 11.6 0.4 1.6 1 0 0 1 1 1 0 F-box-like Ribosomal_S8 PF00410.19 PRP80548.1 - 1.1e-19 70.6 0.1 1.9e-19 69.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 dCMP_cyt_deam_1 PF00383.23 PRP80549.1 - 2.8e-17 62.4 0.0 4e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 PRP80549.1 - 2.8e-10 40.5 0.2 7.8e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 PRP80549.1 - 0.0014 18.2 0.9 0.16 11.6 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases FGAR-AT_N PF18076.1 PRP80550.1 - 0.097 12.7 0.1 0.3 11.1 0.0 1.9 1 1 1 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Guanylate_cyc PF00211.20 PRP80551.1 - 1.6e-26 93.1 1.0 2e-24 86.2 1.0 2.3 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4460 PF14687.6 PRP80551.1 - 1.9e-06 27.9 0.2 5.6e-06 26.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) TRM PF02005.16 PRP80552.1 - 1.5e-126 422.6 0.1 1.9e-126 422.3 0.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 PRP80552.1 - 0.00051 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 PRP80552.1 - 0.0043 16.5 0.7 0.0075 15.7 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 PRP80552.1 - 0.032 13.2 0.0 0.07 12.1 0.0 1.5 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.15 PRP80552.1 - 0.074 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TPR_12 PF13424.6 PRP80553.1 - 3.3e-10 40.1 10.7 0.003 17.8 1.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP80553.1 - 1.3e-07 31.1 13.3 0.0019 18.0 1.5 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP80553.1 - 1.7e-06 27.7 14.9 0.025 14.6 0.0 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP80553.1 - 1.7e-06 27.7 9.4 0.26 11.6 1.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP80553.1 - 0.0003 21.4 4.2 5.3 8.1 0.4 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP80553.1 - 0.00054 19.7 5.9 5.9 6.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP80553.1 - 0.0051 17.4 3.0 1 10.0 0.6 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP80553.1 - 0.0099 15.8 4.2 7 6.9 0.6 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP80553.1 - 0.013 16.0 5.8 7.4 7.4 0.6 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 PRP80553.1 - 0.029 15.1 1.8 1.3 9.8 0.2 3.3 3 0 0 3 3 3 0 Sel1 repeat DUF3811 PF11656.8 PRP80553.1 - 0.032 14.6 1.2 0.085 13.2 1.2 1.7 1 0 0 1 1 1 0 YjbD family (DUF3811) SNAP PF14938.6 PRP80553.1 - 0.37 10.2 3.0 0.67 9.3 1.5 2.2 1 1 1 2 2 2 0 Soluble NSF attachment protein, SNAP DUF5113 PF17140.4 PRP80553.1 - 0.56 10.0 6.9 0.8 9.5 0.7 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) Abhydrolase_1 PF00561.20 PRP80554.1 - 2e-06 27.7 0.1 2.8e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP80554.1 - 2.2e-05 25.2 0.3 3.8e-05 24.4 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP80554.1 - 0.00027 20.3 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 PRP80554.1 - 0.00046 19.0 0.0 0.00069 18.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ras PF00071.22 PRP80555.1 - 4.5e-47 159.7 0.6 6.5e-46 155.9 0.6 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP80555.1 - 5e-16 59.0 0.0 3.5e-15 56.3 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP80555.1 - 0.00059 19.3 0.0 0.0067 15.9 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP80555.1 - 0.0029 17.7 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP80555.1 - 0.0067 16.3 0.1 2.2 8.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 PRP80555.1 - 0.0072 15.7 0.0 0.011 15.0 0.0 1.6 1 1 0 1 1 1 1 AIG1 family Ran_BP1 PF00638.18 PRP80556.1 - 2.1e-46 157.2 4.6 2.1e-46 157.2 4.6 2.1 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 PRP80556.1 - 6.4e-06 26.1 1.7 1.8e-05 24.6 1.7 1.7 1 1 0 1 1 1 1 WH1 domain Kelch_1 PF01344.25 PRP80556.1 - 0.19 11.3 0.1 0.93 9.1 0.0 2.0 2 0 0 2 2 2 0 Kelch motif Ribosomal_60s PF00428.19 PRP80557.1 - 1.2e-28 99.5 9.4 1.6e-28 99.1 9.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein WD40 PF00400.32 PRP80558.1 - 0.0041 17.9 6.5 0.045 14.6 0.0 4.5 4 1 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80558.1 - 0.15 12.4 0.1 1.6 9.1 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Lipase_3 PF01764.25 PRP80559.1 - 9.3e-12 45.0 0.0 2.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) FecCD PF01032.18 PRP80559.1 - 0.0071 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 FecCD transport family zinc_ribbon_6 PF14599.6 PRP80561.1 - 1.3e-23 82.8 0.4 1.3e-23 82.8 0.4 4.3 5 0 0 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 PRP80561.1 - 1.2e-19 70.6 16.9 1.2e-19 70.6 16.9 4.1 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 PRP80561.1 - 1.4e-07 31.7 4.2 1.4e-07 31.7 4.2 5.2 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 PRP80561.1 - 3.4e-05 23.7 5.2 3.4e-05 23.7 5.2 6.2 2 1 3 5 5 5 1 zinc-RING finger domain zf-RING_11 PF17123.5 PRP80561.1 - 0.0053 16.5 1.3 0.0053 16.5 1.3 5.1 6 1 0 6 6 6 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PRP80561.1 - 0.02 14.9 0.3 0.02 14.9 0.3 4.6 5 1 1 6 6 6 0 RING-type zinc-finger Senescence_reg PF04520.13 PRP80561.1 - 0.052 14.4 4.1 1.1 10.1 0.1 2.2 2 0 0 2 2 2 0 Senescence regulator DUF4064 PF13273.6 PRP80562.1 - 0.41 11.0 15.3 0.66 10.3 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3671 PF12420.8 PRP80562.1 - 0.43 10.7 3.5 1.6 8.9 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF202 PF02656.15 PRP80562.1 - 0.58 10.7 7.8 0.077 13.4 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) CorA PF01544.18 PRP80562.1 - 1.2 8.3 4.3 2.2 7.5 4.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SRTM1 PF15872.5 PRP80562.1 - 2.4 8.3 6.8 4.5 7.5 0.1 2.3 1 1 1 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 DUF4131 PF13567.6 PRP80562.1 - 7 6.3 7.5 1.8 8.2 3.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Rap_GAP PF02145.15 PRP80563.1 - 1.7e-63 213.6 0.2 5.7e-63 211.8 0.1 1.9 2 0 0 2 2 2 1 Rap/ran-GAP SWIM PF04434.17 PRP80563.1 - 8.6e-05 22.1 0.1 8.6e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 SWIM zinc finger zf-C2H2_6 PF13912.6 PRP80563.1 - 0.0031 17.4 0.1 0.0096 15.9 0.1 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 PRP80563.1 - 0.024 15.5 1.7 0.024 15.5 1.7 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PRP80563.1 - 0.03 14.6 0.3 0.081 13.2 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 PRP80563.1 - 0.12 12.7 15.3 0.39 11.1 0.4 3.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 PRP80563.1 - 1.2 9.7 6.1 4.2 7.9 0.6 3.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_1 PF14446.6 PRP80563.1 - 3.2 7.8 16.7 0.2 11.6 7.7 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.6 PRP80563.1 - 7 6.8 9.5 22 5.2 9.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DUF4106 PF13388.6 PRP80564.1 - 0.0042 16.4 1.1 0.0053 16.1 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) DUF2517 PF10725.9 PRP80564.1 - 0.18 11.6 0.8 0.93 9.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2517) ELMO_CED12 PF04727.13 PRP80565.1 - 6.9e-29 101.2 0.0 1.2e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 PRP80565.1 - 4.6e-07 29.9 0.0 8.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) WAPL PF07814.13 PRP80565.1 - 0.031 13.1 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Forkhead PF00250.18 PRP80566.1 - 0.005 17.1 0.3 0.33 11.2 0.0 2.2 2 0 0 2 2 2 2 Forkhead domain Ribosomal_L31e PF01198.19 PRP80566.1 - 0.013 15.7 0.2 0.027 14.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L31e NUFIP1 PF10453.9 PRP80570.1 - 1.9e-09 37.2 0.2 1.9e-09 37.2 0.2 3.3 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.8 PRP80570.1 - 0.0044 17.3 0.5 0.0044 17.3 0.5 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PRP80570.1 - 0.032 14.7 0.3 0.12 12.8 0.3 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PRP80570.1 - 0.063 13.3 0.3 0.14 12.2 0.3 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 PRP80570.1 - 0.1 13.5 2.9 0.13 13.1 0.4 2.6 1 1 1 2 2 2 0 C2H2-type zinc finger MCU PF04678.13 PRP80571.1 - 9.8e-37 126.7 0.0 1.5e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter HEM4 PF02602.15 PRP80571.1 - 0.0083 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD F-box-like PF12937.7 PRP80572.1 - 3.2e-06 26.9 0.0 7.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP80572.1 - 0.00029 20.7 0.0 0.00075 19.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain 2OG-FeII_Oxy_3 PF13640.6 PRP80572.1 - 0.037 14.9 0.0 0.079 13.9 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Maf PF02545.14 PRP80573.1 - 1.9e-33 115.7 0.0 3.4e-33 114.8 0.0 1.4 1 1 0 1 1 1 1 Maf-like protein TPR_14 PF13428.6 PRP80574.1 - 7.8e-06 26.3 1.3 0.024 15.4 0.1 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP80574.1 - 1.6e-05 24.6 12.2 0.0097 16.0 0.2 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP80574.1 - 0.00021 21.7 8.0 0.29 11.7 0.2 4.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP80574.1 - 0.00044 20.1 3.3 0.037 14.0 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP80574.1 - 0.0015 18.3 8.7 0.19 11.6 1.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP80574.1 - 0.0021 18.3 5.8 0.17 12.1 2.7 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PRP80574.1 - 0.005 17.4 5.3 2.9 8.7 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP80574.1 - 0.0058 17.3 6.5 2 9.2 0.1 3.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TOM20_plant PF06552.12 PRP80574.1 - 0.0065 16.2 0.8 0.11 12.2 0.1 2.7 2 1 0 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_8 PF13181.6 PRP80574.1 - 0.0091 16.1 6.8 1.2 9.6 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Vir_act_alpha_C PF10400.9 PRP80574.1 - 0.016 15.9 1.5 0.059 14.1 1.5 2.0 1 1 0 1 1 1 0 Virulence activator alpha C-term RPN6_N PF18055.1 PRP80574.1 - 0.051 13.9 4.4 2.3 8.6 0.9 3.5 3 1 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_12 PF13424.6 PRP80574.1 - 0.12 12.7 8.2 0.96 9.8 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP80574.1 - 6.4 6.8 6.1 1.1 9.2 0.2 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Fib_alpha PF08702.10 PRP80574.1 - 6.7 6.9 6.8 1.8 8.8 1.3 2.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Thaumatin PF00314.17 PRP80575.1 - 4.5e-10 39.5 10.9 4.5e-10 39.5 10.9 3.8 2 2 0 2 2 2 1 Thaumatin family Carb_bind PF10645.9 PRP80575.1 - 4.9e-10 39.5 37.9 2.7e-07 30.7 7.2 4.3 4 0 0 4 4 4 3 Carbohydrate binding SPX PF03105.19 PRP80575.1 - 0.35 10.7 1.0 0.44 10.4 1.0 1.1 1 0 0 1 1 1 0 SPX domain Rad51 PF08423.11 PRP80576.1 - 1.9e-16 60.1 0.1 7.2e-16 58.2 0.1 1.9 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 PRP80576.1 - 8.4e-07 28.6 0.1 4.1e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 PRP80576.1 - 4.6e-06 26.4 0.0 7.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 PRP80576.1 - 6.3e-06 25.9 0.0 1.6e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.15 PRP80576.1 - 0.00041 19.8 0.0 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 PRP80576.1 - 0.0058 16.6 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 PRP80576.1 - 0.0068 16.2 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PRP80576.1 - 0.011 15.3 0.1 0.032 13.8 0.1 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 PRP80576.1 - 0.031 14.3 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 PRP80576.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EF1_GNE PF00736.19 PRP80577.1 - 6.8e-30 103.1 1.3 6.8e-30 103.1 1.3 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain DUF1192 PF06698.11 PRP80577.1 - 0.055 13.5 8.2 1.3 9.1 5.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SIMPL PF04402.14 PRP80577.1 - 0.19 12.1 5.1 0.2 12.1 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF541) YlbD_coat PF14071.6 PRP80577.1 - 0.25 11.6 2.7 1.1 9.5 0.6 2.3 1 1 1 2 2 2 0 Putative coat protein UTP25 PF06862.12 PRP80578.1 - 1.2e-142 476.0 2.6 2e-142 475.3 2.6 1.3 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Merozoite_SPAM PF07133.11 PRP80578.1 - 0.042 13.8 48.9 0.015 15.3 39.6 2.4 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Nop53 PF07767.11 PRP80578.1 - 0.068 12.6 29.4 0.14 11.5 29.4 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SDA1 PF05285.12 PRP80578.1 - 0.16 11.4 31.3 0.12 11.7 27.8 2.1 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 PRP80578.1 - 0.6 9.4 26.7 1.1 8.5 26.7 1.5 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 PRP80578.1 - 0.61 9.9 20.3 1.3 8.8 20.3 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 PRP80578.1 - 0.85 8.9 29.8 1.3 8.3 29.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 PRP80578.1 - 1 9.1 30.9 1.9 8.2 30.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 PRP80578.1 - 1.7 6.7 32.2 2.6 6.1 32.2 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PRP80578.1 - 1.9 6.5 34.9 3.2 5.8 34.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Neur_chan_memb PF02932.16 PRP80578.1 - 2.3 8.2 10.4 4.2 7.4 10.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.6 PRP80578.1 - 3.7 8.0 22.7 1.4 9.4 18.4 2.3 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.14 PRP80578.1 - 7.3 4.8 25.9 12 4.0 25.9 1.2 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 PRP80578.1 - 9.9 5.9 20.1 26 4.5 20.1 1.7 1 0 0 1 1 1 0 SpoIIIAH-like protein MBOAT PF03062.19 PRP80579.1 - 4.8e-23 82.1 20.8 7e-23 81.5 20.5 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 PRP80579.1 - 0.011 16.0 3.8 0.027 14.7 3.8 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Tweety PF04906.13 PRP80579.1 - 0.019 13.7 0.2 0.027 13.1 0.2 1.4 1 0 0 1 1 1 0 Tweety CENP-S PF15630.6 PRP80580.1 - 1.3e-23 83.2 0.0 1.4e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PRP80580.1 - 6.4e-09 35.9 0.0 7e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 PRP80580.1 - 2e-07 31.4 0.0 2.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PRP80580.1 - 0.002 18.4 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 PRP80580.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Ribosomal_L19e PF01280.20 PRP80581.1 - 9.9e-63 210.5 11.6 9.9e-63 210.5 11.6 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e DUF4813 PF16072.5 PRP80581.1 - 2.8 7.5 18.1 3.6 7.2 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) CLAMP PF14769.6 PRP80582.1 - 9e-26 90.2 4.9 1.7e-25 89.3 4.9 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 MORN PF02493.20 PRP80583.1 - 2e-41 137.4 59.1 5.2e-06 26.0 1.4 10.7 11 0 0 11 11 11 9 MORN repeat Spc24 PF08286.11 PRP80583.1 - 4.7 7.5 6.9 1.9 8.8 0.6 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Guanylate_cyc PF00211.20 PRP80584.1 - 6.4e-24 84.6 0.2 3.7e-11 43.0 0.0 2.8 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 PRP80584.1 - 1.3e-08 35.4 0.1 1.3e-07 32.2 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain PAS_9 PF13426.7 PRP80584.1 - 2.3e-06 27.8 0.0 1.1e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 PAS domain TPR_1 PF00515.28 PRP80584.1 - 0.00011 21.8 4.0 0.037 13.9 0.2 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat PAS PF00989.25 PRP80584.1 - 0.00066 19.7 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 PAS fold NACHT PF05729.12 PRP80584.1 - 0.00069 19.6 0.1 0.0018 18.3 0.1 1.7 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.6 PRP80584.1 - 0.00077 19.3 0.1 14 6.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PAS_4 PF08448.10 PRP80584.1 - 0.0014 18.8 0.0 0.0045 17.2 0.0 1.9 2 0 0 2 2 2 1 PAS fold TPR_12 PF13424.6 PRP80584.1 - 0.0074 16.5 11.3 0.31 11.3 0.1 5.2 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP80584.1 - 0.025 14.0 7.7 0.52 9.6 0.6 3.9 3 1 1 4 4 4 0 MalT-like TPR region TPR_2 PF07719.17 PRP80584.1 - 0.044 13.9 0.1 0.044 13.9 0.1 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP80584.1 - 0.054 13.7 0.2 0.054 13.7 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ETF PF01012.21 PRP80586.1 - 9.8e-46 155.9 0.1 1.2e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Radical_SAM PF04055.21 PRP80586.1 - 0.066 13.6 0.1 1.1 9.6 0.1 2.2 2 0 0 2 2 2 0 Radical SAM superfamily Raftlin PF15250.6 PRP80587.1 - 5 5.7 24.6 5.9 5.5 24.6 1.1 1 0 0 1 1 1 0 Raftlin SRP-alpha_N PF04086.13 PRP80587.1 - 5.2 6.9 38.6 6 6.7 38.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.7 PRP80587.1 - 8.6 4.3 25.2 9.3 4.2 25.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_11 PF08241.12 PRP80588.1 - 2.5e-12 47.3 0.0 4.1e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP80588.1 - 5.7e-10 39.8 0.0 1.5e-08 35.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP80588.1 - 1.2e-07 31.7 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP80588.1 - 6.9e-07 28.8 0.0 2.1e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PRP80588.1 - 1.4e-06 28.2 0.0 2.2e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP80588.1 - 2.2e-06 28.3 0.0 5.9e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PRP80588.1 - 0.012 15.5 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase TPMT PF05724.11 PRP80588.1 - 0.038 13.6 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) N6_N4_Mtase PF01555.18 PRP80588.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA methylase Exo_endo_phos PF03372.23 PRP80589.1 - 0.0014 18.2 0.0 0.0082 15.7 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4358 PF14270.6 PRP80590.1 - 0.0042 17.3 1.8 0.019 15.2 0.1 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4358) COX7C PF02935.16 PRP80590.1 - 0.078 13.2 0.7 0.16 12.3 0.7 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Golgin_A5 PF09787.9 PRP80590.1 - 5.7 6.3 42.5 0.025 14.1 12.9 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 Pkinase PF00069.25 PRP80591.1 - 3.6e-64 216.7 0.0 5.5e-64 216.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80591.1 - 2.4e-44 151.6 0.0 3.9e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP80591.1 - 5.2e-08 33.4 0.1 1.9e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 PRP80591.1 - 0.00039 19.3 0.0 0.0012 17.7 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase PH_16 PF17838.1 PRP80591.1 - 0.0065 16.3 0.0 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 PRP80591.1 - 0.01 15.6 2.2 6.1 6.6 0.1 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain PBD PF00786.28 PRP80591.1 - 0.18 12.2 5.4 0.21 12.0 0.0 3.7 5 0 0 5 5 5 0 P21-Rho-binding domain RGS12_us1 PF16613.5 PRP80591.1 - 3.4 8.0 8.5 0.37 11.1 0.6 2.7 2 1 0 2 2 2 0 Unstructured region of RGS12 Dynamin_N PF00350.23 PRP80592.1 - 2.7e-16 60.1 0.0 7.7e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin family GATA PF00320.27 PRP80592.1 - 6.6e-12 44.8 4.8 1.3e-11 43.9 4.8 1.5 1 0 0 1 1 1 1 GATA zinc finger MMR_HSR1 PF01926.23 PRP80592.1 - 4.7e-06 26.7 0.0 2.8e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PRP80592.1 - 0.0001 21.7 0.2 0.0023 17.3 0.0 2.6 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 PRP80592.1 - 0.0017 17.9 0.1 0.017 14.7 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PRP80592.1 - 0.0032 17.9 0.1 0.016 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 PRP80592.1 - 0.008 16.7 12.0 0.05 14.1 3.6 3.2 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 PRP80592.1 - 0.0088 16.6 0.1 0.032 14.7 0.0 2.0 2 0 0 2 2 1 1 ABC transporter PduV-EutP PF10662.9 PRP80592.1 - 0.014 15.2 0.0 0.07 12.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PRP80592.1 - 0.018 15.3 0.5 0.2 11.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 PRP80592.1 - 0.019 14.7 0.0 0.06 13.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 PRP80592.1 - 0.03 14.2 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PRP80592.1 - 0.048 13.6 0.3 0.35 10.8 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 PRP80592.1 - 0.059 12.8 0.1 0.69 9.3 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit cobW PF02492.19 PRP80592.1 - 0.092 12.3 1.6 0.59 9.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 PRP80592.1 - 0.14 12.1 0.8 0.49 10.3 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 PRP80592.1 - 0.22 11.5 1.2 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Nitroreductase PF00881.24 PRP80593.1 - 8.3e-16 58.5 0.0 1e-15 58.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family SOR PF07682.11 PRP80593.1 - 0.0086 15.0 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Sulphur oxygenase reductase TM1586_NiRdase PF14512.6 PRP80593.1 - 0.12 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative TM nitroreductase LRR_8 PF13855.6 PRP80594.1 - 4.6e-33 112.8 91.8 3.2e-07 30.0 5.3 11.4 9 4 3 12 12 12 9 Leucine rich repeat LRR_4 PF12799.7 PRP80594.1 - 9.5e-25 86.3 91.5 0.00051 20.4 6.7 12.1 3 3 7 13 13 13 13 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP80594.1 - 7.3e-20 71.3 0.0 2.8e-19 69.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80594.1 - 2.7e-14 53.2 0.0 6.6e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain LRR_1 PF00560.33 PRP80594.1 - 1e-08 34.5 69.7 15 6.6 1.5 19.6 18 4 0 18 18 18 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP80594.1 - 2.9e-07 30.0 83.9 4.9 7.5 0.4 19.3 21 0 0 21 21 21 8 Leucine Rich repeat LRR_5 PF13306.6 PRP80594.1 - 0.0084 16.1 0.5 0.0084 16.1 0.5 2.6 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Cytomega_TRL10 PF06084.11 PRP80594.1 - 0.022 14.8 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein LRRNT_2 PF08263.12 PRP80594.1 - 0.027 14.8 2.5 0.069 13.5 0.2 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Cupin_5 PF06172.11 PRP80598.1 - 2.5e-32 112.0 0.0 3.1e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) PRA1 PF03208.19 PRP80599.1 - 4.4e-23 81.5 6.1 6.9e-23 80.9 6.1 1.3 1 0 0 1 1 1 1 PRA1 family protein DUF4389 PF14333.6 PRP80599.1 - 0.44 10.5 7.8 0.14 12.1 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) VirB3 PF05101.13 PRP80599.1 - 9.3 6.6 14.9 0.43 10.8 3.5 2.3 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein DUF3169 PF11368.8 PRP80599.1 - 9.4 5.7 15.7 7.5 6.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Acetyltransf_1 PF00583.25 PRP80600.1 - 3.7e-19 69.1 0.0 5e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP80600.1 - 1.4e-10 41.5 0.0 2.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP80600.1 - 4.9e-10 39.4 0.0 6.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP80600.1 - 1.3e-09 38.4 0.1 1.6e-09 38.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP80600.1 - 2.7e-05 24.2 0.0 4.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP80600.1 - 0.00017 22.3 0.0 0.00022 21.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP80600.1 - 0.00019 21.5 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 PRP80600.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_6 PF13480.7 PRP80600.1 - 0.056 13.6 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CLTH PF10607.9 PRP80601.1 - 4.4e-28 98.0 0.1 4.4e-28 98.0 0.1 2.0 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 PRP80601.1 - 1.5e-05 24.9 0.1 2.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger TelA PF05816.11 PRP80601.1 - 0.00051 19.2 3.5 0.072 12.1 1.8 2.2 1 1 1 2 2 2 2 Toxic anion resistance protein (TelA) Rtf2 PF04641.12 PRP80601.1 - 0.0044 16.4 0.0 0.0044 16.4 0.0 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 PRP80601.1 - 0.0045 17.3 0.1 0.0099 16.2 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 PRP80601.1 - 0.016 15.0 0.7 0.047 13.5 0.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit EFTUD2 PF16004.5 PRP80601.1 - 0.038 14.6 0.5 0.068 13.8 0.5 1.4 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Pet127 PF08634.10 PRP80601.1 - 0.062 12.7 1.3 0.1 12.0 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet127 zf-RING_5 PF14634.6 PRP80601.1 - 0.092 12.7 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain LAGLIDADG_WhiA PF14527.6 PRP80601.1 - 0.22 11.6 2.7 12 6.0 0.1 3.1 4 0 0 4 4 3 0 WhiA LAGLIDADG-like domain Goodbye PF17109.5 PRP80601.1 - 0.26 11.8 4.4 21 5.6 0.1 3.5 2 2 2 4 4 4 0 fungal STAND N-terminal Goodbye domain GNAT_acetyltr_2 PF13718.6 PRP80602.1 - 1.2e-96 322.6 0.1 3.4e-96 321.1 0.0 1.8 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 PRP80602.1 - 3.9e-67 225.5 0.0 1.1e-66 224.1 0.0 1.8 1 0 0 1 1 1 1 Helicase tRNA_bind_2 PF13725.6 PRP80602.1 - 1.6e-59 201.5 0.3 5.2e-59 199.8 0.0 1.9 2 0 0 2 2 2 1 Possible tRNA binding domain DUF1726 PF08351.11 PRP80602.1 - 2e-31 107.7 0.1 5.2e-31 106.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 PRP80602.1 - 0.00012 21.9 0.1 0.01 15.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 PRP80602.1 - 0.0038 17.5 0.0 0.78 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PRP80602.1 - 0.0096 16.3 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF742 PF05331.11 PRP80602.1 - 0.21 11.4 1.2 0.46 10.3 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF742) RNase_H PF00075.24 PRP80604.1 - 3.1e-13 50.1 2.2 9.5e-13 48.5 0.2 2.8 2 1 0 2 2 2 1 RNase H zf-RVT PF13966.6 PRP80604.1 - 0.0056 17.4 2.2 0.11 13.2 0.4 3.1 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase TetR_C_17 PF17922.1 PRP80604.1 - 0.019 15.1 0.4 0.046 13.8 0.4 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RVT_3 PF13456.6 PRP80604.1 - 0.031 14.1 0.0 0.094 12.5 0.0 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like RVT_1 PF00078.27 PRP80605.1 - 5.2e-42 143.8 1.7 1.1e-41 142.8 0.1 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 PRP80605.1 - 4.3e-08 33.0 5.4 4e-07 29.9 5.4 2.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PRP80605.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ntox15 PF15604.6 PRP80605.1 - 0.032 14.4 0.8 0.07 13.3 0.8 1.5 1 0 0 1 1 1 0 Novel toxin 15 CHDCT2 PF08074.11 PRP80605.1 - 0.055 13.6 1.8 0.35 11.0 0.7 2.5 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain DUF3287 PF11690.8 PRP80605.1 - 0.86 9.3 4.3 23 4.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3287) Med26 PF08711.11 PRP80605.1 - 3.7 7.7 5.7 0.89 9.6 1.4 2.2 2 0 0 2 2 2 0 TFIIS helical bundle-like domain DUF445 PF04286.12 PRP80605.1 - 5.2 6.8 9.5 18 5.0 8.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) YIF1 PF03878.15 PRP80608.1 - 3.1e-68 229.9 9.2 3.9e-68 229.6 9.2 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 PRP80608.1 - 6.8e-08 32.4 5.2 1.2e-07 31.6 5.2 1.4 1 0 0 1 1 1 1 Yip1 domain Tfb2 PF03849.14 PRP80610.1 - 3.1e-111 371.8 4.7 3.7e-111 371.5 4.7 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 PRP80610.1 - 5.4e-16 58.8 0.0 1.5e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 PRP80610.1 - 0.0085 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_38N PF01074.22 PRP80611.1 - 1.5e-89 300.2 9.8 2.1e-89 299.8 9.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP80611.1 - 1.1e-35 123.7 0.0 2.1e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP80611.1 - 2.7e-17 62.7 0.0 6.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PRP80611.1 - 2.9e-07 30.5 0.0 7.2e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 PRP80611.1 - 0.0045 16.2 0.0 0.011 14.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 HemN_C PF06969.16 PRP80611.1 - 0.11 12.6 0.0 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 HemN C-terminal domain Helicase_C PF00271.31 PRP80612.1 - 1.8e-17 63.7 0.1 1.4e-16 60.8 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP80612.1 - 7.8e-08 32.5 0.0 3.9e-07 30.2 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PRP80612.1 - 1.5e-07 31.4 0.0 3.6e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 PRP80612.1 - 0.0032 17.2 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PhoH PF02562.16 PRP80612.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein GreA_GreB_N PF03449.15 PRP80612.1 - 0.17 12.1 1.4 0.3 11.3 0.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Ribosomal_L31 PF01197.18 PRP80613.1 - 0.12 12.6 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L31 Helicase_C PF00271.31 PRP80614.1 - 2e-16 60.3 0.3 1.3e-15 57.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP80614.1 - 1.5e-05 25.1 0.3 0.00079 19.5 0.4 2.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 PRP80614.1 - 0.0026 17.5 0.1 0.0049 16.6 0.1 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase CCDC32 PF14989.6 PRP80614.1 - 0.02 14.9 0.7 0.29 11.1 0.0 2.7 2 0 0 2 2 2 0 Coiled-coil domain containing 32 RIG-I_C-RD PF11648.8 PRP80614.1 - 8.7 6.6 10.4 3.5 7.9 5.7 2.7 2 1 0 2 2 2 0 C-terminal domain of RIG-I 2OG-FeII_Oxy_2 PF13532.6 PRP80615.1 - 2.1e-39 135.8 0.0 4.2e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily C2 PF00168.30 PRP80615.1 - 5.8e-15 55.4 0.0 2.6e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 C2 domain Glyco_hydro_38N PF01074.22 PRP80616.1 - 2.5e-84 283.0 2.7 3.3e-84 282.7 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP80616.1 - 1.6e-34 119.9 0.0 2.8e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP80616.1 - 1.4e-17 63.6 0.1 2.7e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PRP80616.1 - 4.9e-06 26.6 0.1 1.9e-05 24.7 0.1 2.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Exo84_C PF16528.5 PRP80617.1 - 2e-39 135.5 0.4 2e-39 135.5 0.4 6.3 4 2 4 8 8 8 1 Exocyst component 84 C-terminal SMC_N PF02463.19 PRP80617.1 - 1.8e-24 86.4 10.4 6.2e-24 84.7 10.4 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PRP80617.1 - 1.3e-14 55.2 1.9 1.3e-14 55.2 1.9 7.2 4 3 2 6 6 6 1 AAA domain Vps51 PF08700.11 PRP80617.1 - 5.5e-14 52.0 1.6 5.5e-14 52.0 1.6 8.0 6 2 1 8 8 8 2 Vps51/Vps67 Dor1 PF04124.12 PRP80617.1 - 5.6e-05 22.0 3.4 5.6e-05 22.0 3.4 5.6 4 2 0 5 5 5 1 Dor1-like family AAA_29 PF13555.6 PRP80617.1 - 0.079 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MtrB PF05440.12 PRP80617.1 - 0.089 13.2 0.8 4 7.9 0.0 3.8 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B AAA_21 PF13304.6 PRP80617.1 - 0.1 12.4 3.6 0.33 10.7 0.1 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF775 PF05603.12 PRP80618.1 - 3.5e-52 176.8 0.0 4e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) CN_hydrolase PF00795.22 PRP80619.1 - 9.3e-47 159.6 0.0 1.1e-46 159.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Rad51 PF08423.11 PRP80620.1 - 9.3e-117 388.8 0.4 1.7e-115 384.7 0.4 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PRP80620.1 - 5e-08 32.8 0.0 8.3e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 PRP80620.1 - 9.3e-06 26.2 1.0 2e-05 25.1 1.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_24 PF13479.6 PRP80620.1 - 0.0013 18.5 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PRP80620.1 - 0.0019 17.6 3.3 0.0096 15.3 3.3 2.1 1 1 0 1 1 1 1 KaiC RNA_pol_A_CTD PF03118.15 PRP80620.1 - 0.0053 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain HHH PF00633.23 PRP80620.1 - 0.025 14.5 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DnaB_C PF03796.15 PRP80620.1 - 0.03 13.7 0.3 0.085 12.2 0.1 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Synapsin_C PF02750.14 PRP80621.1 - 1.4e-58 197.8 0.0 1.9e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 PRP80621.1 - 9.2e-21 74.0 0.0 2.4e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Synapsin, N-terminal domain DNA_pol_P_Exo PF18049.1 PRP80621.1 - 0.015 14.7 0.2 0.024 14.1 0.2 1.2 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo UNC45-central PF11701.8 PRP80622.1 - 2.3e-06 27.6 10.1 2.8e-05 24.1 0.7 4.0 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central TPR_2 PF07719.17 PRP80622.1 - 2e-05 24.4 6.0 0.00043 20.2 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP80622.1 - 0.00012 21.6 0.4 0.15 11.7 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 PRP80622.1 - 0.0006 19.8 2.2 0.0032 17.5 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP80622.1 - 0.0012 18.6 1.1 0.43 10.5 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP80622.1 - 0.0036 17.8 8.3 0.46 11.0 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP80622.1 - 0.0064 17.2 2.2 0.84 10.6 0.1 3.8 3 0 0 3 3 2 1 Tetratricopeptide repeat HEAT_2 PF13646.6 PRP80622.1 - 0.011 16.1 9.4 0.32 11.4 0.1 5.5 4 2 1 5 5 5 0 HEAT repeats TPR_6 PF13174.6 PRP80622.1 - 0.012 16.2 0.4 0.2 12.4 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Arm PF00514.23 PRP80622.1 - 0.013 15.6 6.6 18 5.6 0.0 6.2 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat TPR_7 PF13176.6 PRP80622.1 - 0.022 14.8 0.2 2.6 8.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP80622.1 - 0.03 15.0 1.6 8.9 7.0 0.6 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat VHS PF00790.19 PRP80622.1 - 0.041 13.7 0.8 28 4.5 0.0 3.9 4 0 0 4 4 4 0 VHS domain Tti2 PF10521.9 PRP80622.1 - 0.052 13.1 0.5 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Tti2 family ANAPC2 PF08672.11 PRP80622.1 - 0.086 13.4 0.0 12 6.4 0.0 3.9 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 DivIC PF04977.15 PRP80622.1 - 0.087 12.6 0.1 0.29 10.9 0.1 1.9 1 0 0 1 1 1 0 Septum formation initiator Glyoxalase PF00903.25 PRP80623.1 - 0.0011 19.2 0.0 0.033 14.4 0.0 2.4 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ntox10 PF15520.6 PRP80623.1 - 0.0092 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Novel toxin 10 Toxin-JAB1 PF15659.6 PRP80623.1 - 0.074 13.4 0.2 0.24 11.8 0.1 2.0 2 1 0 2 2 2 0 JAB-like toxin 1 ALO PF04030.14 PRP80624.1 - 2.6e-47 161.8 0.4 3.4e-47 161.5 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 PRP80624.1 - 5.2e-19 68.4 0.1 8.4e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_5 PF00941.21 PRP80624.1 - 0.00058 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase VD10_N PF08476.10 PRP80624.1 - 0.058 13.1 0.2 1.3 8.7 0.1 2.4 2 0 0 2 2 2 0 Viral D10 N-terminal Ras PF00071.22 PRP80625.1 - 1.8e-50 170.7 0.2 2.1e-50 170.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP80625.1 - 8.7e-34 116.3 0.1 1.3e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP80625.1 - 1.6e-15 57.0 0.1 1.9e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP80625.1 - 1.5e-08 34.3 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP80625.1 - 9.3e-08 32.2 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP80625.1 - 4e-07 30.1 0.0 0.0049 16.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP80625.1 - 0.0014 18.2 0.0 0.023 14.2 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PRP80625.1 - 0.0024 17.3 0.1 0.0076 15.7 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PRP80625.1 - 0.0052 16.0 1.3 0.44 9.7 0.1 2.9 1 1 2 3 3 3 1 G-protein alpha subunit ABC_tran PF00005.27 PRP80625.1 - 0.0076 16.8 0.4 0.022 15.3 0.4 1.9 1 1 0 1 1 1 1 ABC transporter IIGP PF05049.13 PRP80625.1 - 0.0095 15.0 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 PRP80625.1 - 0.018 14.8 0.2 0.034 13.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PRP80625.1 - 0.024 15.0 0.1 0.05 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 PRP80625.1 - 0.049 13.7 0.0 0.069 13.2 0.0 1.5 1 1 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 PRP80625.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 PRP80625.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PRP80625.1 - 0.16 11.8 0.1 0.22 11.5 0.1 1.4 1 1 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 PRP80625.1 - 0.19 11.5 0.5 1.7 8.3 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ZZ PF00569.17 PRP80626.1 - 1.1e-18 66.8 24.7 6.2e-10 38.7 5.7 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type PB1 PF00564.24 PRP80626.1 - 8.2e-15 54.5 0.0 2e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 PRP80626.1 - 1.4e-07 31.7 18.2 0.00085 19.6 2.3 2.6 2 0 0 2 2 2 2 C1 domain UBA PF00627.31 PRP80626.1 - 0.0036 17.2 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain zf-C3HC4_3 PF13920.6 PRP80626.1 - 0.024 14.5 1.4 0.024 14.5 1.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UBR PF02207.20 PRP80626.1 - 2 8.6 20.2 0.74 10.0 7.9 2.5 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) TBCC PF07986.12 PRP80626.1 - 2.2 8.1 6.2 2.1 8.1 1.0 2.4 2 0 0 2 2 2 0 Tubulin binding cofactor C PBP_sp32 PF07222.12 PRP80626.1 - 7 6.0 12.1 13 5.2 12.1 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 HIRAN PF08797.11 PRP80627.1 - 0.00021 21.1 0.0 0.00052 19.9 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Chromo PF00385.24 PRP80630.1 - 6.1e-13 48.5 0.0 9.4e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP80630.1 - 0.096 12.9 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Peptidase_M20 PF01546.28 PRP80632.1 - 4.9e-14 52.5 0.0 8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PRP80632.1 - 4.1e-12 46.0 0.0 6.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain LicD PF04991.13 PRP80633.1 - 1.5e-27 97.2 0.1 1.3e-18 67.9 0.1 2.4 1 1 1 2 2 2 2 LicD family Pkinase PF00069.25 PRP80634.1 - 1.8e-53 181.6 1.2 2e-53 181.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain TrmO PF01980.16 PRP80634.1 - 2.3e-41 140.7 0.0 6.1e-41 139.4 0.0 1.8 1 0 0 1 1 1 1 tRNA-methyltransferase O Pkinase_Tyr PF07714.17 PRP80634.1 - 1.8e-32 112.7 0.0 3.8e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TrmO_C PF18389.1 PRP80634.1 - 2e-05 24.6 0.4 6e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 TrmO C-terminal domain Kdo PF06293.14 PRP80634.1 - 4.6e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PrmA PF06325.13 PRP80636.1 - 7.1e-15 55.2 0.1 1.4e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PRP80636.1 - 9.2e-11 41.6 0.3 2.5e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP80636.1 - 2.7e-09 37.6 0.2 1.1e-08 35.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP80636.1 - 2e-07 30.9 0.2 5.7e-07 29.4 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PRP80636.1 - 2.6e-07 30.5 0.4 0.00044 19.9 0.0 2.3 1 1 1 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 PRP80636.1 - 8.6e-06 25.7 0.1 1.5e-05 24.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP80636.1 - 0.0013 19.4 0.0 0.0035 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PRP80636.1 - 0.0023 17.9 0.3 0.0055 16.7 0.1 1.8 2 0 0 2 2 1 1 Methyltransferase domain DUF43 PF01861.16 PRP80636.1 - 0.0051 16.1 0.0 0.011 15.0 0.0 1.7 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain UPF0020 PF01170.18 PRP80636.1 - 0.0068 16.1 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Myc_N PF01056.18 PRP80636.1 - 0.0086 16.0 0.6 0.012 15.6 0.6 1.2 1 0 0 1 1 1 1 Myc amino-terminal region Methyltransf_12 PF08242.12 PRP80636.1 - 0.017 15.8 5.2 0.48 11.2 0.1 2.8 2 1 1 3 3 2 0 Methyltransferase domain FtsJ PF01728.19 PRP80636.1 - 0.025 14.7 1.4 0.046 13.8 1.4 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 PRP80636.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.11 PRP80636.1 - 0.083 12.4 0.3 0.2 11.2 0.1 1.7 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_15 PF09445.10 PRP80636.1 - 0.17 11.5 0.6 0.58 9.7 0.4 1.9 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AviRa PF11599.8 PRP80636.1 - 0.19 11.1 3.1 0.18 11.2 0.3 2.2 2 1 0 2 2 2 0 RRNA methyltransferase AviRa RXT2_N PF08595.11 PRP80636.1 - 0.22 11.5 6.1 0.41 10.7 6.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 PRP80636.1 - 0.45 10.9 8.7 0.95 9.9 8.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 PRP80636.1 - 1 7.4 9.2 1.8 6.6 9.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi MscS_TM PF12794.7 PRP80636.1 - 1.2 7.9 2.7 2 7.2 2.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2457 PF10446.9 PRP80636.1 - 1.8 7.6 13.4 2.8 7.0 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Lys PF00062.20 PRP80637.1 - 1.1e-06 28.9 1.9 7.3e-06 26.2 1.9 2.0 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SLT PF01464.20 PRP80637.1 - 9.5e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Transglycosylas PF06737.14 PRP80637.1 - 0.019 15.6 2.8 0.032 14.9 2.2 1.7 1 1 0 1 1 1 0 Transglycosylase-like domain UBX PF00789.20 PRP80638.1 - 7.6e-13 48.5 0.0 2.6e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 UBX domain MFS_1 PF07690.16 PRP80639.1 - 1.2e-42 146.2 74.3 5.6e-37 127.5 47.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Fer4_8 PF13183.6 PRP80639.1 - 0.19 12.2 1.1 0.42 11.1 1.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain FA_desaturase PF00487.24 PRP80639.1 - 0.96 9.2 7.4 3.6 7.3 7.4 2.1 1 0 0 1 1 1 0 Fatty acid desaturase SHMT PF00464.19 PRP80641.1 - 1.3e-189 629.9 0.0 1.5e-189 629.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase ubiquitin PF00240.23 PRP80642.1 - 3.6e-26 90.7 5.3 1.9e-15 56.3 0.2 2.9 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 PRP80642.1 - 1.4e-13 50.4 3.8 4.2e-06 26.5 0.1 3.0 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 PRP80642.1 - 7.9e-10 38.7 12.3 1.4e-09 38.0 12.3 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_5 PF18037.1 PRP80642.1 - 0.00027 21.2 2.6 0.33 11.3 0.0 3.1 1 1 0 3 3 3 2 Ubiquitin-like domain TBK1_ULD PF18396.1 PRP80642.1 - 0.0018 18.1 0.1 0.0052 16.7 0.0 1.8 1 1 1 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 PRP80642.1 - 0.0043 17.5 0.5 0.021 15.2 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP80642.1 - 0.012 15.7 0.1 2.9 8.0 0.0 2.9 2 2 1 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like TerY_C PF15616.6 PRP80642.1 - 0.015 15.4 1.2 0.015 15.4 1.2 2.0 2 0 0 2 2 2 0 TerY-C metal binding domain Ubiquitin_4 PF18036.1 PRP80642.1 - 0.048 13.7 5.6 6.2 6.9 0.0 4.1 3 1 1 4 4 4 0 Ubiquitin-like domain CRAL_TRIO PF00650.20 PRP80643.1 - 1.4e-36 125.7 0.0 1.7e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP80643.1 - 1.7e-05 24.9 0.1 4.1e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 PRP80643.1 - 0.001 19.2 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FLILHELTA PF10306.9 PRP80644.1 - 3.7e-11 43.3 0.0 1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 PRP80644.1 - 0.012 16.1 1.1 0.026 15.1 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Atypical_Card PF18461.1 PRP80645.1 - 0.042 14.1 0.2 0.26 11.5 0.1 2.4 3 0 0 3 3 3 0 Atypical caspase recruitment domain Nexin_C PF08628.12 PRP80645.1 - 0.066 13.8 0.1 0.23 12.0 0.1 1.9 1 0 0 1 1 1 0 Sorting nexin C terminal HEAT PF02985.22 PRP80645.1 - 0.13 12.6 0.0 44 4.7 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Csm2_III-A PF03750.13 PRP80645.1 - 0.28 12.1 1.3 6 7.7 0.1 3.1 3 0 0 3 3 3 0 Csm2 Type III-A Nup188 PF10487.9 PRP80647.1 - 3.1e-52 177.7 4.8 5.9e-52 176.7 4.8 1.5 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF1854 PF08909.11 PRP80647.1 - 0.018 14.9 0.7 0.17 11.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) Guanylate_cyc PF00211.20 PRP80649.1 - 2.7e-33 115.1 0.2 5.2e-33 114.2 0.2 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FokI_C PF02980.16 PRP80649.1 - 0.12 12.4 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Restriction endonuclease FokI, catalytic domain Baculo_gp64 PF03273.13 PRP80649.1 - 0.26 10.1 1.7 1.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Baculovirus gp64 envelope glycoprotein family Sigma_reg_N PF13800.6 PRP80649.1 - 0.46 10.8 4.7 0.17 12.2 0.4 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Syndecan PF01034.20 PRP80649.1 - 0.77 9.7 3.8 2.4 8.1 3.8 1.8 1 0 0 1 1 1 0 Syndecan domain 7tm_7 PF08395.12 PRP80649.1 - 1.2 8.3 5.3 0.35 10.0 1.0 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor Cupin_8 PF13621.6 PRP80652.1 - 1.7e-38 132.8 0.1 3.1e-38 131.9 0.1 1.4 1 0 0 1 1 1 1 Cupin-like domain Kelch_4 PF13418.6 PRP80652.1 - 5.3e-34 116.0 16.2 2.6e-13 49.8 0.1 5.8 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 PRP80652.1 - 5.8e-29 99.8 2.2 1.4e-08 34.8 0.1 4.7 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP80652.1 - 6.3e-28 96.3 7.2 1.8e-08 34.2 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PRP80652.1 - 5e-20 71.0 10.1 5e-08 33.0 0.0 6.4 6 0 0 6 6 6 4 Kelch motif LCM PF04072.14 PRP80652.1 - 7.9e-19 68.3 0.0 1.6e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_2 PF07646.15 PRP80652.1 - 1e-18 66.5 11.7 1.9e-05 24.5 0.0 6.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 PRP80652.1 - 4.5e-18 64.6 10.6 2.5e-05 23.8 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Lipase_3 PF01764.25 PRP80652.1 - 7.2e-18 64.8 0.0 1.7e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Cupin_4 PF08007.12 PRP80652.1 - 1.9e-05 24.3 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PRP80652.1 - 0.042 14.3 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase Peptidase_S9_N PF02897.15 PRP80656.1 - 2.1e-80 270.6 10.1 2.9e-80 270.1 10.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PRP80656.1 - 3.9e-45 153.9 2.5 6.4e-45 153.2 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 PRP80656.1 - 0.00015 21.5 0.0 0.00062 19.4 0.0 2.0 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PfUIS3 PF11567.8 PRP80656.1 - 0.18 12.2 2.8 0.39 11.1 1.5 2.1 2 0 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein Ank_2 PF12796.7 PRP80658.1 - 7.4e-26 90.6 0.0 1.2e-10 41.9 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80658.1 - 2e-16 60.1 0.2 2.1e-06 28.1 0.0 5.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP80658.1 - 4.8e-12 45.9 0.0 0.014 15.7 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP80658.1 - 2.9e-09 36.9 0.1 2.4 8.8 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 PRP80658.1 - 1.3e-07 31.4 0.2 8 7.4 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Rep_fac-A_C PF08646.10 PRP80659.1 - 2.7e-25 88.8 0.5 3.7e-24 85.1 0.2 2.2 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 PRP80659.1 - 3.3e-19 68.6 0.1 1.5e-18 66.5 0.1 2.0 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 PRP80659.1 - 1.3e-14 54.0 1.6 1.8e-14 53.6 0.3 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 PRP80659.1 - 9.5e-11 41.5 0.0 2e-07 30.9 0.0 3.6 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF223 PF02721.14 PRP80659.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF223 tRNA_anti_2 PF13742.6 PRP80659.1 - 0.11 12.7 0.0 33 4.8 0.0 3.6 4 0 0 4 4 4 0 OB-fold nucleic acid binding domain SLATT_5 PF18160.1 PRP80659.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Peptidase_C1 PF00112.23 PRP80660.1 - 1.5e-44 152.7 0.8 2.2e-44 152.2 0.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP80660.1 - 7e-11 42.4 0.1 1e-10 41.9 0.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP80660.1 - 2.5e-07 29.8 1.0 8.4e-05 21.5 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family MFS_1 PF07690.16 PRP80663.1 - 1.2e-28 100.1 24.1 1.2e-28 100.1 24.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF805 PF05656.14 PRP80663.1 - 6.2 7.3 10.8 0.16 12.4 1.7 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF805) EGF_2 PF07974.13 PRP80664.1 - 0.068 13.5 9.7 0.13 12.6 9.7 1.4 1 0 0 1 1 1 0 EGF-like domain GPS PF01825.21 PRP80665.1 - 6e-09 36.3 1.1 1.9e-08 34.7 1.1 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF3377 PF11857.8 PRP80665.1 - 2 8.4 4.6 0.81 9.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) MDD_C PF18376.1 PRP80666.1 - 1.2e-63 214.3 0.0 1.8e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 PRP80666.1 - 2.1e-06 27.9 1.5 4.3e-06 26.9 1.5 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF4175 PF13779.6 PRP80666.1 - 0.38 8.6 3.5 0.55 8.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Cadherin_2 PF08266.12 PRP80667.1 - 0.0067 16.2 0.0 5.4 6.9 0.0 2.9 2 1 1 3 3 3 2 Cadherin-like Exonuc_VII_L PF02601.15 PRP80667.1 - 2 7.9 7.1 2.9 7.4 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mito_carr PF00153.27 PRP80668.1 - 1.5e-62 207.5 0.3 4.1e-25 87.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LBP_BPI_CETP_C PF02886.17 PRP80672.1 - 2.9e-30 105.5 0.0 4.6e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 PRP80672.1 - 0.037 13.7 0.1 0.13 11.9 0.0 1.9 2 1 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain Guanylate_cyc PF00211.20 PRP80673.1 - 3.6e-61 206.0 0.0 2.2e-32 112.2 0.0 3.1 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.25 PRP80674.1 - 1.4e-63 214.8 0.0 1.7e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80674.1 - 1.1e-29 103.5 0.0 3.6e-29 101.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP80674.1 - 3.4e-08 33.1 0.0 6.2e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 Kinase-like ADP_ribosyl_GH PF03747.14 PRP80675.1 - 9.1e-61 206.1 0.0 1.1e-60 205.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Rick_17kDa_Anti PF05433.15 PRP80675.1 - 0.044 13.7 1.1 0.15 12.0 1.1 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 PRP80675.1 - 1.6 8.8 0.0 1.6 8.8 0.0 2.8 3 0 0 3 3 3 0 Glycine zipper SnoaL_2 PF12680.7 PRP80676.1 - 0.00095 19.8 0.0 0.0014 19.2 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF3876 PF12992.7 PRP80676.1 - 0.083 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3876) DUF4440 PF14534.6 PRP80676.1 - 0.12 12.8 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) DSPc PF00782.20 PRP80677.1 - 9.7e-30 103.1 0.0 1.6e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain R3H PF01424.22 PRP80677.1 - 1.7e-09 37.5 0.3 3.4e-09 36.6 0.3 1.5 1 0 0 1 1 1 1 R3H domain Y_phosphatase PF00102.27 PRP80677.1 - 7.2e-05 22.5 0.2 0.00026 20.7 0.1 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PBP-Tp47_c PF14888.6 PRP80677.1 - 0.061 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain C XRN_N PF03159.18 PRP80678.1 - 1.1e-89 300.0 0.0 1.1e-89 300.0 0.0 2.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PRP80678.1 - 7.5e-66 222.9 2.2 6.2e-44 150.7 0.3 3.4 2 1 2 4 4 4 2 Xrn1 helical domain SH3_12 PF18129.1 PRP80678.1 - 1.4e-20 73.1 2.1 4.7e-20 71.4 0.6 2.4 2 0 0 2 2 2 1 Xrn1 SH3-like domain XRN1_D1 PF18332.1 PRP80678.1 - 3.1e-15 56.4 3.3 4.7e-15 55.9 0.0 2.4 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 PRP80678.1 - 0.0016 18.6 1.0 0.0037 17.4 0.0 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain TERB2 PF15101.6 PRP80678.1 - 0.078 13.0 2.6 0.24 11.4 2.6 1.8 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GATase_6 PF13522.6 PRP80678.1 - 0.095 12.9 0.0 0.33 11.2 0.0 1.8 2 0 0 2 2 2 0 Glutamine amidotransferase domain GAGA_bind PF06217.12 PRP80678.1 - 1.8 8.8 5.7 0.47 10.7 2.0 1.9 2 0 0 2 2 2 0 GAGA binding protein-like family Dynein_light PF01221.18 PRP80678.1 - 2.4 8.5 4.7 0.44 10.9 0.1 2.2 2 0 0 2 2 2 0 Dynein light chain type 1 RNA_pol_A_bac PF01000.26 PRP80682.1 - 1.3e-36 125.3 0.4 3.3e-35 120.8 0.1 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PRP80682.1 - 1.7e-20 72.2 0.0 2.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.32 PRP80683.1 - 5.4e-32 109.3 21.1 1.7e-06 28.6 0.3 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat BTB_2 PF02214.22 PRP80683.1 - 5.8e-18 65.0 0.0 1.1e-08 35.3 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain DUF1664 PF07889.12 PRP80683.1 - 0.043 13.9 0.6 0.079 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TraG-D_C PF12696.7 PRP80683.1 - 0.053 13.5 0.3 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG GAS PF13851.6 PRP80683.1 - 0.1 12.0 2.2 0.18 11.1 2.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Presenilin PF01080.17 PRP80684.1 - 7.2e-116 387.2 34.6 1.9e-79 267.3 17.5 2.6 1 1 2 3 3 3 2 Presenilin SPP PF06550.11 PRP80684.1 - 3e-06 26.9 23.4 4.1e-06 26.5 23.4 1.2 1 0 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Nup35_RRM PF05172.13 PRP80684.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif F-box-like PF12937.7 PRP80685.1 - 2.9e-06 27.1 0.0 1.3e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP80685.1 - 0.0021 17.9 0.4 0.054 13.4 0.2 3.4 3 2 0 3 3 3 1 F-box domain Pkinase PF00069.25 PRP80686.1 - 2.9e-75 253.0 0.0 3.8e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80686.1 - 2.9e-35 121.8 0.0 8.9e-35 120.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP80686.1 - 0.00057 18.9 0.3 0.00086 18.3 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PRP80686.1 - 0.0031 17.1 0.4 0.0051 16.4 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PRP80686.1 - 0.054 12.9 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PRP80687.1 - 3.1e-41 141.4 0.2 4.2e-41 140.9 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80687.1 - 1.3e-30 106.6 0.1 2e-30 106.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP80687.1 - 2.5e-10 40.7 7.2 5.1e-10 39.7 7.2 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP80687.1 - 2.7e-05 23.6 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like D123 PF07065.14 PRP80688.1 - 5.2e-13 48.8 0.2 2.6e-12 46.5 0.1 2.0 1 1 0 2 2 2 1 D123 R2K_2 PF18299.1 PRP80688.1 - 0.07 13.0 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Cyclin PF08613.11 PRP80689.1 - 5.7e-07 30.0 0.0 9.5e-07 29.3 0.0 1.4 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 PRP80689.1 - 3.4e-06 26.8 0.0 9e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Pkinase PF00069.25 PRP80690.1 - 7.7e-52 176.3 0.1 1.8e-51 175.1 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80690.1 - 8.2e-20 71.2 0.0 1.4e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 PRP80690.1 - 0.021 14.4 0.6 0.051 13.2 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 PRP80690.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 PRP80690.1 - 0.18 11.4 0.2 0.36 10.4 0.2 1.5 1 0 0 1 1 1 0 RIO1 family DUF4201 PF13870.6 PRP80692.1 - 6.3e-41 140.0 41.2 6.6e-41 140.0 30.6 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Mac PF12464.8 PRP80692.1 - 0.27 11.5 9.5 0.64 10.3 0.7 3.0 2 1 0 2 2 2 0 Maltose acetyltransferase DUF1664 PF07889.12 PRP80692.1 - 0.94 9.5 11.0 6.7 6.8 2.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 PRP80692.1 - 1.5 8.8 5.9 4.2 7.4 0.6 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 PRP80692.1 - 1.8 9.1 5.5 19 5.8 0.3 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4250 PF14056.6 PRP80692.1 - 3.4 7.7 12.0 2.5 8.1 1.3 4.3 3 1 2 5 5 5 0 Domain of unknown function (DUF4250) KxDL PF10241.9 PRP80692.1 - 5.8 7.3 25.7 0.73 10.1 2.4 4.1 3 1 1 4 4 4 0 Uncharacterized conserved protein Cyclin_N PF00134.23 PRP80693.1 - 8.7e-16 57.8 4.1 3.1e-14 52.8 1.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 PRP80693.1 - 0.0041 17.1 0.2 0.61 10.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 PRP80693.1 - 0.015 15.7 0.6 0.15 12.4 0.4 2.7 1 1 1 2 2 2 0 Cyclin C-terminal domain MTD PF01993.18 PRP80693.1 - 0.051 12.9 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase GSH_synthase PF03199.15 PRP80693.1 - 0.085 13.3 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic glutathione synthase Pkinase PF00069.25 PRP80694.1 - 2.5e-65 220.5 0.0 4.2e-65 219.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80694.1 - 3.9e-37 127.9 0.0 5.5e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_N PF08240.12 PRP80694.1 - 7e-25 87.0 2.2 2e-24 85.6 2.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PRP80694.1 - 3.8e-18 65.7 0.2 6.9e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Kdo PF06293.14 PRP80694.1 - 1.5e-06 27.7 0.1 3.9e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP80694.1 - 0.00031 20.7 0.0 0.0028 17.6 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP80694.1 - 0.00051 19.5 0.0 0.00083 18.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like AlaDh_PNT_C PF01262.21 PRP80694.1 - 0.0015 17.9 0.7 0.0028 17.0 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 PRP80694.1 - 0.0029 17.2 0.1 0.0056 16.3 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RIO1 PF01163.22 PRP80694.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PRP80694.1 - 0.015 15.0 0.3 0.81 9.3 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PRP80694.1 - 0.036 12.8 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PRP80694.1 - 0.04 12.8 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain BRCT PF00533.26 PRP80695.1 - 5.5e-14 52.3 0.0 8.1e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP80695.1 - 9.4e-11 42.0 0.0 5.6e-05 23.5 0.0 3.3 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 PRP80695.1 - 4.3e-09 36.4 0.0 1.3e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 PRP80695.1 - 7.6e-09 35.3 0.1 1.9e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PRP80695.1 - 4.7e-08 32.4 0.2 7.1e-08 31.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 PRP80695.1 - 7.2e-07 28.8 0.1 1.1e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 PRP80695.1 - 0.00033 19.8 0.2 0.00049 19.2 0.2 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RTT107_BRCT_5 PF16770.5 PRP80695.1 - 0.00099 19.0 0.0 0.0066 16.3 0.0 2.5 2 1 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 PRP80695.1 - 0.051 13.5 0.0 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain APH PF01636.23 PRP80695.1 - 0.062 13.2 0.1 0.14 12.1 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family RtcB PF01139.17 PRP80696.1 - 6.2e-67 226.6 0.0 4.4e-51 174.4 0.0 2.5 1 1 0 2 2 2 2 tRNA-splicing ligase RtcB MFS_1 PF07690.16 PRP80696.1 - 8.3e-17 61.1 32.3 8.3e-17 61.1 32.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 PRP80696.1 - 0.0039 16.1 10.6 4.7 6.0 0.0 2.3 1 1 1 2 2 2 2 MFS_1 like family DUF5357 PF17310.2 PRP80696.1 - 0.24 9.9 3.8 0.59 8.6 3.8 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5357) DUF5336 PF17270.2 PRP80696.1 - 1.4 8.5 9.2 1.9 8.1 6.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5336) WD40 PF00400.32 PRP80697.1 - 2.9e-41 138.6 35.4 6e-06 26.9 0.6 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat BTB_2 PF02214.22 PRP80697.1 - 2.3e-23 82.3 0.0 2.2e-10 40.8 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain WD40_like PF17005.5 PRP80697.1 - 8.6e-05 22.0 0.7 0.0035 16.7 0.1 2.5 1 1 1 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 PRP80697.1 - 0.00021 21.3 0.1 0.59 10.2 0.0 4.0 1 1 6 7 7 7 2 Ciliary BBSome complex subunit 2, middle region Invasin_D3 PF09134.10 PRP80697.1 - 0.00075 19.8 21.9 9.8 6.6 0.7 6.2 1 1 5 6 6 6 2 Invasin, domain 3 SnoaL_2 PF12680.7 PRP80697.1 - 0.012 16.3 2.1 7.3 7.3 0.1 3.9 2 1 3 5 5 5 0 SnoaL-like domain Mcl1_mid PF12341.8 PRP80697.1 - 0.025 13.9 4.3 10 5.3 4.3 3.9 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region HECA PF15353.6 PRP80697.1 - 0.026 14.8 7.1 7.7 6.8 0.4 4.9 4 1 1 5 5 5 0 Headcase protein family homologue Read-through PF16814.5 PRP80697.1 - 0.13 12.1 3.6 19 5.0 0.0 4.3 1 1 5 6 6 6 0 Read-through domain Imm74 PF15603.6 PRP80697.1 - 0.28 11.4 2.9 34 4.7 0.1 4.3 4 0 0 4 4 4 0 Immunity protein 74 Fib_alpha PF08702.10 PRP80697.1 - 0.74 10.0 6.6 15 5.8 2.4 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Caudo_TAP PF02413.17 PRP80697.1 - 2.6 8.2 8.8 2.5 8.2 1.0 3.5 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK DUF3109 PF11307.8 PRP80697.1 - 3.6 7.4 7.2 3.5 7.4 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3109) DUF3826 PF12875.7 PRP80699.1 - 0.054 13.6 0.7 0.13 12.4 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3826) HisKA_4TM PF16926.5 PRP80700.1 - 0.043 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase WSS_VP PF12175.8 PRP80700.1 - 0.05 13.1 0.2 0.094 12.2 0.2 1.4 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP WD40 PF00400.32 PRP80701.1 - 2e-44 148.7 35.1 6.3e-07 30.0 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat BTB_2 PF02214.22 PRP80701.1 - 2.2e-25 88.8 0.0 1e-11 45.0 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain DUF4402 PF14352.6 PRP80701.1 - 1.7e-07 31.9 11.1 0.67 10.6 0.1 6.2 1 1 4 5 5 5 3 Domain of unknown function (DUF4402) WD40_like PF17005.5 PRP80701.1 - 3.5e-06 26.6 2.6 0.00048 19.6 0.1 2.4 1 1 1 2 2 2 2 WD40-like domain DUF5639 PF18690.1 PRP80701.1 - 0.0039 17.3 0.0 9.1 6.5 0.0 3.9 2 1 2 4 4 4 1 Family of unknown function (DUF5639) HECA PF15353.6 PRP80701.1 - 0.016 15.4 9.3 7.7 6.8 0.4 6.3 2 1 5 7 7 7 0 Headcase protein family homologue 4HBT_3 PF13622.6 PRP80701.1 - 0.065 13.5 1.1 3.3 7.9 0.1 3.2 1 1 1 2 2 2 0 Thioesterase-like superfamily Read-through PF16814.5 PRP80701.1 - 0.16 11.7 3.6 74 3.1 0.1 4.4 2 1 3 5 5 5 0 Read-through domain Invasin_D3 PF09134.10 PRP80701.1 - 0.3 11.4 21.2 9.5 6.6 0.5 6.0 1 1 5 6 6 6 0 Invasin, domain 3 Fib_alpha PF08702.10 PRP80701.1 - 0.67 10.1 6.1 14 5.9 2.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Caudo_TAP PF02413.17 PRP80701.1 - 0.96 9.6 6.3 2.3 8.4 0.8 3.0 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK 2OG-FeII_Oxy_3 PF13640.6 PRP80702.1 - 2.8e-06 28.1 0.2 2.8e-06 28.1 0.2 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase_Tyr PF07714.17 PRP80703.1 - 3.5e-58 196.9 1.3 4.6e-57 193.3 1.1 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80703.1 - 1.8e-41 142.2 0.1 3.6e-41 141.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP80703.1 - 2.4e-40 136.1 76.3 6.5e-10 38.6 0.8 14.0 10 3 2 12 12 12 8 Leucine rich repeat LRR_4 PF12799.7 PRP80703.1 - 2e-30 104.3 91.4 2.3e-08 34.2 0.4 17.4 10 8 10 20 20 20 12 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP80703.1 - 3e-11 42.4 70.3 0.58 10.4 0.1 20.6 23 0 0 23 23 21 6 Leucine Rich repeat LRR_1 PF00560.33 PRP80703.1 - 8.2e-09 34.8 69.0 0.11 13.1 0.2 21.7 24 3 0 24 24 20 2 Leucine Rich Repeat TMEM154 PF15102.6 PRP80703.1 - 0.0036 17.2 0.6 0.0079 16.1 0.6 1.5 1 0 0 1 1 1 1 TMEM154 protein family Neurensin PF14927.6 PRP80703.1 - 0.0076 16.0 0.2 0.024 14.4 0.2 1.8 1 0 0 1 1 1 1 Neurensin Pkinase_fungal PF17667.1 PRP80703.1 - 0.011 14.5 0.1 0.017 13.9 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Stevor PF17410.2 PRP80703.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF1453 PF07301.11 PRP80703.1 - 0.032 14.2 0.9 0.07 13.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) EphA2_TM PF14575.6 PRP80703.1 - 0.041 14.8 0.7 0.093 13.6 0.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 PRP80703.1 - 0.045 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 PRP80703.1 - 0.062 12.7 7.0 0.14 11.6 7.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRRNT_2 PF08263.12 PRP80703.1 - 0.1 12.9 1.9 0.32 11.3 1.9 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Kinase-like PF14531.6 PRP80703.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF3377 PF11857.8 PRP80703.1 - 0.14 12.1 0.1 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Haspin_kinase PF12330.8 PRP80703.1 - 0.17 10.8 0.8 0.31 9.9 0.1 1.7 2 0 0 2 2 2 0 Haspin like kinase domain SurA_N_2 PF13623.6 PRP80703.1 - 0.21 11.5 1.5 0.42 10.5 1.5 1.4 1 0 0 1 1 1 0 SurA N-terminal domain Amnionless PF14828.6 PRP80703.1 - 2 7.2 4.1 0.96 8.2 0.2 2.0 2 0 0 2 2 2 0 Amnionless MMACHC PF16690.5 PRP80704.1 - 2e-19 70.1 0.0 3.7e-19 69.3 0.0 1.4 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Peptidase_C15 PF01470.17 PRP80705.1 - 1.7e-10 41.4 0.0 2.5e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 Pyroglutamyl peptidase Rad51 PF08423.11 PRP80706.1 - 4.5e-123 409.5 0.1 9.5e-123 408.4 0.1 1.6 1 0 0 1 1 1 1 Rad51 Pkinase PF00069.25 PRP80706.1 - 7.1e-49 166.5 0.0 2.9e-47 161.2 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80706.1 - 2.4e-22 79.5 0.0 5.2e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP80706.1 - 3.2e-14 53.4 0.1 1.2e-07 31.9 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 PRP80706.1 - 4.1e-14 52.6 0.1 3.6e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 PRP80706.1 - 9.8e-09 34.5 0.2 1.9e-08 33.6 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) AAA_25 PF13481.6 PRP80706.1 - 1.2e-08 34.8 0.0 2.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Kinase-like PF14531.6 PRP80706.1 - 1.6e-08 34.2 0.0 1.1e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RecA PF00154.21 PRP80706.1 - 2.3e-08 33.9 0.1 3.7e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 PRP80706.1 - 2.6e-06 27.9 2.3 7.5e-06 26.5 2.3 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Kdo PF06293.14 PRP80706.1 - 1e-05 25.0 0.0 0.00015 21.2 0.1 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP80706.1 - 0.0002 21.0 0.0 0.066 12.8 0.0 2.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase ATPase PF06745.13 PRP80706.1 - 0.0013 18.1 4.0 0.0023 17.3 1.8 2.4 2 1 0 2 2 2 1 KaiC Haspin_kinase PF12330.8 PRP80706.1 - 0.0019 17.2 0.2 0.0051 15.8 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PRP80706.1 - 0.062 12.3 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_Tyr PF07714.17 PRP80707.1 - 1.4e-70 237.5 0.0 1.9e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80707.1 - 7.7e-48 163.1 0.0 1.1e-47 162.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP80707.1 - 6e-06 25.8 0.0 1.7e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP80707.1 - 7e-05 22.3 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP80707.1 - 0.00033 19.6 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Amnionless PF14828.6 PRP80707.1 - 0.0066 15.3 0.1 0.011 14.6 0.1 1.4 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.10 PRP80707.1 - 0.0068 15.8 5.7 0.0068 15.8 5.7 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Stevor PF17410.2 PRP80707.1 - 0.13 11.8 0.2 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Podoplanin PF05808.11 PRP80707.1 - 0.22 11.6 2.0 0.52 10.4 2.0 1.6 1 0 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.15 PRP80707.1 - 0.3 10.9 4.4 0.63 9.9 4.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 VSP PF03302.13 PRP80707.1 - 0.97 8.2 3.4 1.5 7.6 3.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein p450 PF00067.22 PRP80708.1 - 3e-69 233.9 0.1 4.6e-69 233.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 PRP80708.1 - 1.3e-30 106.6 0.0 2.6e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PRP80708.1 - 8.7e-20 71.4 0.4 4.9e-19 69.0 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 PRP80708.1 - 4.2e-14 53.1 0.1 4.3e-13 49.9 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF806 PF05657.11 PRP80708.1 - 0.056 13.9 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF806) Eco57I PF07669.11 PRP80708.1 - 0.057 13.9 0.0 0.35 11.4 0.0 2.3 2 0 0 2 2 2 0 Eco57I restriction-modification methylase zf-MYND PF01753.18 PRP80709.1 - 8.2e-05 22.6 3.1 8.2e-05 22.6 3.1 2.8 3 0 0 3 3 3 1 MYND finger Rpr2 PF04032.16 PRP80709.1 - 0.076 13.3 1.5 4.5 7.6 0.5 2.7 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain G8 PF10162.9 PRP80710.1 - 0.041 14.0 0.4 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 G8 domain Proteasome PF00227.26 PRP80712.1 - 2.4e-61 206.6 0.1 3.5e-61 206.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PRP80712.1 - 1.4e-09 37.5 1.4 2.4e-09 36.7 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature LRR_8 PF13855.6 PRP80714.1 - 7.5e-29 99.3 43.7 1.7e-09 37.3 0.3 5.4 2 2 4 6 6 6 6 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP80714.1 - 1.3e-26 93.4 0.2 2.1e-26 92.8 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP80714.1 - 6.5e-21 74.1 30.1 2.8e-05 24.4 0.1 6.9 5 2 2 7 7 7 6 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP80714.1 - 1.6e-18 67.0 0.1 2.7e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP80714.1 - 5.4e-11 42.8 4.2 2e-10 41.0 4.2 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP80714.1 - 2.6e-07 30.3 25.5 2.2 9.2 0.1 10.0 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP80714.1 - 0.0044 17.0 24.6 7 7.0 0.1 8.9 9 0 0 9 9 9 3 Leucine Rich repeat Kdo PF06293.14 PRP80714.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FA_FANCE PF11510.8 PRP80715.1 - 4.9e-18 65.4 8.3 5.6e-14 52.1 4.6 2.4 2 0 0 2 2 2 2 Fanconi Anaemia group E protein FANCE zf-C3HC4_3 PF13920.6 PRP80715.1 - 5.1e-10 39.1 12.0 5.1e-10 39.1 12.0 5.4 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP80715.1 - 4.4e-05 23.3 14.9 4.4e-05 23.3 14.9 3.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP80715.1 - 0.0014 18.5 13.7 0.0014 18.5 13.7 4.4 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 EphA2_TM PF14575.6 PRP80715.1 - 0.0065 17.3 0.1 0.022 15.6 0.1 1.9 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 PRP80715.1 - 0.032 14.2 0.8 0.068 13.1 0.8 1.4 1 0 0 1 1 1 0 Protocadherin DEAD PF00270.29 PRP80716.1 - 2.7e-43 147.8 0.1 4.3e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP80716.1 - 3e-29 101.6 1.8 1.2e-28 99.6 0.6 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP80716.1 - 5.7e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PRP80716.1 - 0.00098 18.4 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 PRP80716.1 - 0.055 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Sirohm_synth_M PF14824.6 PRP80716.1 - 0.17 11.3 1.1 0.36 10.3 1.1 1.5 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central WD40 PF00400.32 PRP80717.1 - 4.2e-15 55.9 6.2 1.2e-05 26.0 0.1 8.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80717.1 - 6.6e-14 52.0 0.4 0.0053 17.0 0.0 5.7 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 PRP80717.1 - 8.6e-05 22.4 0.6 2.6 7.9 0.0 4.1 1 1 2 4 4 4 2 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 PRP80717.1 - 0.029 13.4 13.4 0.096 11.7 0.6 5.4 5 2 1 6 6 6 0 Coatomer WD associated region zf-RING_5 PF14634.6 PRP80717.1 - 1.2 9.1 9.5 0.063 13.2 0.9 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 PRP80717.1 - 4.3 7.7 10.0 0.075 13.4 1.9 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 PRP80717.1 - 4.7 7.1 9.7 0.9 9.4 0.5 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PPR_2 PF13041.6 PRP80719.1 - 3.6e-42 142.3 40.7 3.1e-05 24.1 0.0 14.6 9 4 7 16 16 16 13 PPR repeat family PPR_3 PF13812.6 PRP80719.1 - 1.2e-25 89.4 18.4 0.00088 19.3 0.3 11.2 4 3 7 13 13 13 9 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP80719.1 - 2.7e-19 69.4 0.1 5.9e-09 35.6 0.0 6.2 3 2 2 6 6 6 5 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PRP80719.1 - 1.8e-18 65.4 50.4 0.0084 16.3 0.2 15.0 16 0 0 16 16 16 7 PPR repeat LIM PF00412.22 PRP80719.1 - 1.8e-13 50.4 7.1 5e-13 49.1 7.1 1.8 1 0 0 1 1 1 1 LIM domain PPR_1 PF12854.7 PRP80719.1 - 3.7e-08 32.9 0.0 8.4 6.2 0.0 8.2 9 0 0 9 9 9 2 PPR repeat Sel1 PF08238.12 PRP80719.1 - 0.033 14.9 0.8 45 4.9 0.1 4.2 3 0 0 3 3 3 0 Sel1 repeat zinc_ribbon_12 PF11331.8 PRP80719.1 - 1.7 8.5 3.8 3.7 7.4 3.8 1.6 1 0 0 1 1 1 0 Probable zinc-ribbon domain Myf5 PF12232.8 PRP80719.1 - 6.7 7.6 6.2 5.6 7.8 1.8 2.8 2 0 0 2 2 2 0 Myogenic determination factor 5 PITH PF06201.13 PRP80720.1 - 1.7e-32 112.7 1.4 2.9e-32 112.0 1.4 1.4 1 1 0 1 1 1 1 PITH domain Pox_MCEL PF03291.16 PRP80722.1 - 9.3e-27 94.0 0.3 9.2e-22 77.6 0.2 2.4 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 PRP80722.1 - 0.00058 20.5 0.1 0.0063 17.2 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP80722.1 - 0.0031 17.4 0.0 0.0059 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP80722.1 - 0.015 15.9 0.0 0.03 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cas_DxTHG PF09455.10 PRP80722.1 - 0.043 13.4 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family ComA PF02679.15 PRP80722.1 - 0.096 12.1 0.0 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) Ank_2 PF12796.7 PRP80723.1 - 3.2e-37 127.0 0.1 5.5e-10 39.7 0.0 6.0 2 1 6 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80723.1 - 1.6e-30 105.0 0.2 2.4e-06 28.0 0.0 7.8 4 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80723.1 - 2e-14 52.3 4.0 0.95 10.2 0.0 10.7 10 1 1 11 11 11 3 Ankyrin repeat Ank_5 PF13857.6 PRP80723.1 - 4e-14 52.5 5.8 0.28 11.6 0.1 9.3 3 1 9 12 12 12 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP80723.1 - 1.7e-12 47.2 11.6 6.4 7.4 0.1 10.0 7 3 2 9 9 9 4 Ankyrin repeat DUF1955 PF09205.10 PRP80723.1 - 0.069 12.9 3.5 37 4.0 0.0 4.6 4 2 1 5 5 5 0 Domain of unknown function (DUF1955) Cpn60_TCP1 PF00118.24 PRP80725.1 - 2.2e-158 528.0 2.7 2.5e-158 527.8 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family LRAT PF04970.13 PRP80725.1 - 0.11 12.7 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Lecithin retinol acyltransferase adh_short PF00106.25 PRP80726.1 - 1e-17 64.3 0.0 2.1e-17 63.2 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP80726.1 - 4.9e-06 26.3 0.0 8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ZIP4_domain PF18292.1 PRP80726.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Zinc transporter ZIP4 domain CarboxypepD_reg PF13620.6 PRP80727.1 - 2.8e-10 40.3 1.4 9.3e-10 38.7 1.4 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PRP80727.1 - 2.2e-09 37.2 0.2 4.9e-09 36.1 0.2 1.6 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Ras PF00071.22 PRP80728.1 - 5.6e-61 204.9 0.2 7.4e-61 204.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP80728.1 - 2.1e-31 108.6 0.0 3.4e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP80728.1 - 2.7e-12 46.5 0.0 3.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP80728.1 - 1.9e-05 24.7 0.0 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP80728.1 - 0.0017 17.7 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP80728.1 - 0.0023 17.5 0.0 0.0077 15.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP80728.1 - 0.009 15.9 0.2 3 7.7 0.0 2.9 1 1 1 3 3 3 2 RsgA GTPase Ald_Xan_dh_C2 PF02738.18 PRP80730.1 - 2.7e-149 498.2 0.0 3.8e-149 497.7 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 PRP80730.1 - 2e-30 105.4 0.0 4.9e-30 104.1 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PRP80730.1 - 1e-26 92.8 0.2 2.3e-26 91.6 0.2 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain FAD_binding_5 PF00941.21 PRP80730.1 - 2.2e-26 92.6 0.0 4.7e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 PRP80730.1 - 3.6e-24 84.9 0.1 1.1e-23 83.3 0.1 1.9 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PRP80730.1 - 2.2e-08 33.9 1.0 5.7e-08 32.6 1.0 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain WW PF00397.26 PRP80730.1 - 8.4e-07 29.0 0.1 2.6e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 WW domain FAD_binding_4 PF01565.23 PRP80730.1 - 0.046 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain GDPD PF03009.17 PRP80731.1 - 1.1e-51 176.1 0.0 2e-51 175.2 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 PRP80731.1 - 3.4e-17 62.1 0.0 7.2e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain PrpR_N PF06506.11 PRP80731.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Propionate catabolism activator PX PF00787.24 PRP80732.1 - 2.2e-07 30.9 0.0 6.3e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 PX domain Erp_C PF06780.11 PRP80732.1 - 0.14 12.2 0.4 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Erp protein C-terminus Nkap_C PF06047.11 PRP80733.1 - 2e-28 98.5 0.4 2e-28 98.5 0.4 2.4 2 1 1 3 3 2 1 NF-kappa-B-activating protein C-terminal domain AP3D1 PF06375.11 PRP80733.1 - 4.1e-05 23.9 10.9 7.1e-05 23.1 10.9 1.4 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Dehydrin PF00257.19 PRP80733.1 - 0.004 17.7 5.5 0.0067 17.0 5.5 1.3 1 0 0 1 1 1 1 Dehydrin DUF1168 PF06658.12 PRP80733.1 - 0.0045 16.8 16.4 0.0084 15.9 16.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DUF755 PF05501.11 PRP80733.1 - 0.006 16.8 17.6 0.011 16.0 17.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF755) GAGA_bind PF06217.12 PRP80733.1 - 0.044 14.1 4.8 0.06 13.6 4.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Rrn6 PF10214.9 PRP80733.1 - 0.098 11.1 13.3 0.12 10.8 13.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Presenilin PF01080.17 PRP80733.1 - 0.41 9.4 4.2 0.44 9.3 4.2 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 PRP80733.1 - 0.5 9.1 6.8 0.56 8.9 6.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S49_N PF08496.10 PRP80733.1 - 1.6 8.8 6.1 2.6 8.1 5.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Med19 PF10278.9 PRP80733.1 - 1.6 8.7 12.3 2.3 8.2 12.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nucleo_P87 PF07267.11 PRP80733.1 - 2.5 6.8 8.5 3 6.6 8.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ATG16 PF08614.11 PRP80734.1 - 0.0052 17.0 4.7 0.0052 17.0 4.7 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 PRP80734.1 - 0.039 14.5 6.5 0.081 13.4 6.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 PRP80734.1 - 0.048 14.1 15.4 0.13 12.8 5.8 3.1 3 1 1 4 4 3 0 Cell division protein ZapB DivIVA PF05103.13 PRP80734.1 - 0.048 13.7 8.0 0.12 12.5 8.0 1.6 1 0 0 1 1 1 0 DivIVA protein LURAP PF14854.6 PRP80734.1 - 0.063 13.2 0.4 0.15 12.0 0.3 1.6 1 1 0 1 1 1 0 Leucine rich adaptor protein Cgr1 PF03879.14 PRP80734.1 - 0.093 13.1 5.3 0.31 11.4 0.8 2.3 2 0 0 2 2 2 0 Cgr1 family Tsi6 PF18660.1 PRP80734.1 - 0.1 12.7 0.8 0.35 10.9 0.5 2.1 2 0 0 2 2 1 0 Tsi6 Shugoshin_N PF07558.11 PRP80734.1 - 0.11 12.4 0.3 0.11 12.4 0.3 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DASH_Dam1 PF08653.10 PRP80734.1 - 0.26 11.1 2.2 2.9 7.8 0.2 2.7 2 0 0 2 2 2 0 DASH complex subunit Dam1 bZIP_1 PF00170.21 PRP80734.1 - 0.33 11.1 4.5 2.5 8.3 0.2 2.7 1 1 1 2 2 2 0 bZIP transcription factor PKcGMP_CC PF16808.5 PRP80734.1 - 0.54 10.1 3.3 5.6 6.9 0.7 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_2 PF07716.15 PRP80734.1 - 0.57 10.3 5.1 0.92 9.6 0.1 2.9 2 0 0 2 2 2 0 Basic region leucine zipper Pil1 PF13805.6 PRP80734.1 - 0.6 9.5 8.7 0.035 13.6 2.9 1.8 2 0 0 2 2 2 0 Eisosome component PIL1 TSC22 PF01166.18 PRP80734.1 - 0.61 10.4 6.1 0.48 10.8 0.3 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family Herpes_UL6 PF01763.16 PRP80734.1 - 0.77 8.2 8.9 0.81 8.1 7.4 1.6 1 1 1 2 2 2 0 Herpesvirus UL6 like DivIC PF04977.15 PRP80734.1 - 1 9.2 11.3 1.6 8.5 1.0 2.7 1 1 1 2 2 2 0 Septum formation initiator Cep57_MT_bd PF06657.13 PRP80734.1 - 1.1 9.7 9.9 0.46 11.0 1.7 2.8 2 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 ERM PF00769.19 PRP80734.1 - 1.8 8.4 15.0 4.7 7.0 14.9 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 PRP80734.1 - 1.8 7.8 11.7 0.23 10.7 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 PRP80734.1 - 2.4 8.6 7.5 5.8 7.4 0.2 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.14 PRP80734.1 - 3.2 7.5 10.4 0.37 10.6 5.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 PRP80734.1 - 5.7 7.0 9.9 1.7 8.7 4.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 PRP80734.1 - 9.4 6.3 9.2 0.49 10.4 1.9 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Voltage_CLC PF00654.20 PRP80735.1 - 5.4e-90 302.2 21.2 7.3e-90 301.8 21.2 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel RicinB_lectin_2 PF14200.6 PRP80736.1 - 3.3e-07 30.9 0.2 0.00047 20.8 0.0 3.7 3 1 2 5 5 5 3 Ricin-type beta-trefoil lectin domain-like B_lectin PF01453.24 PRP80736.1 - 6.9e-05 23.3 0.7 0.0086 16.6 0.1 2.8 2 1 1 3 3 3 2 D-mannose binding lectin Peptidase_M90 PF06167.12 PRP80736.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Diedel PF13164.6 PRP80736.1 - 0.23 11.9 0.9 0.5 10.8 0.2 1.9 2 0 0 2 2 2 0 Diedel F-box PF00646.33 PRP80737.1 - 0.0086 15.9 0.7 0.032 14.1 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP80737.1 - 0.073 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like Stealth_CR3 PF17102.5 PRP80738.1 - 0.046 13.6 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 zf-C2H2_4 PF13894.6 PRP80738.1 - 0.073 13.9 1.7 0.31 12.0 0.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger AA_permease PF00324.21 PRP80739.1 - 2.6e-133 445.1 41.7 3.2e-133 444.8 41.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 PRP80739.1 - 8.9e-37 126.9 46.1 1.3e-36 126.4 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease Yippee-Mis18 PF03226.14 PRP80739.1 - 5.9e-15 55.4 4.7 7.2e-09 35.8 0.7 2.5 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly F-box-like PF12937.7 PRP80739.1 - 1.5e-11 44.0 0.1 4.5e-11 42.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP80739.1 - 8.2e-05 22.4 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain RIG-I_C-RD PF11648.8 PRP80739.1 - 0.049 13.9 3.0 8.2 6.7 0.1 3.3 3 0 0 3 3 3 0 C-terminal domain of RIG-I DUF2101 PF09874.9 PRP80739.1 - 2.4 7.8 4.6 6.8 6.3 4.6 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Methyltransf_16 PF10294.9 PRP80741.1 - 1.3e-23 83.6 0.1 4.7e-23 81.8 0.1 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 PRP80741.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain YIF1 PF03878.15 PRP80742.1 - 0.0074 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 YIF1 LAG1-DNAbind PF09271.11 PRP80742.1 - 0.0086 16.7 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding Asparaginase_2 PF01112.18 PRP80743.1 - 1e-105 353.1 9.5 1.2e-105 352.9 9.5 1.0 1 0 0 1 1 1 1 Asparaginase G_glu_transpept PF01019.21 PRP80743.1 - 0.0051 15.6 0.2 0.39 9.4 0.1 2.2 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Mpv17_PMP22 PF04117.12 PRP80744.1 - 3.3e-19 68.9 0.5 8.2e-19 67.6 0.5 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family 7TMR-DISM_7TM PF07695.11 PRP80744.1 - 0.023 14.6 2.9 0.55 10.1 0.4 2.3 2 0 0 2 2 2 0 7TM diverse intracellular signalling Metallophos PF00149.28 PRP80746.1 - 3.7e-18 66.8 2.8 3.7e-18 66.8 2.8 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PRP80746.1 - 8.8e-13 48.6 0.7 2.6e-12 47.1 0.1 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 PRP80746.1 - 4.3e-08 33.9 0.7 4.3e-08 33.9 0.7 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C fn3_PAP PF17808.1 PRP80746.1 - 2.2e-06 27.8 1.7 3.1e-05 24.1 1.5 2.7 2 1 0 2 2 2 1 Fn3-like domain from Purple Acid Phosphatase ATG19_autophagy PF12744.7 PRP80746.1 - 0.045 12.9 0.0 0.099 11.8 0.0 1.6 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding Uroplakin_II PF07353.12 PRP80746.1 - 0.16 11.5 0.4 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 Uroplakin II M20_dimer PF07687.14 PRP80747.1 - 2.2e-09 37.2 0.0 5.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 PRP80747.1 - 1.2e-08 35.0 0.5 1.9e-08 34.3 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ETC_C1_NDUFA5 PF04716.14 PRP80748.1 - 9.1e-15 54.2 0.1 1.8e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Abhydrolase_2 PF02230.16 PRP80749.1 - 2.2e-21 76.7 0.0 2.8e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 PRP80749.1 - 2e-06 27.7 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 PRP80749.1 - 0.0011 18.6 0.0 0.0021 17.6 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PRP80749.1 - 0.0014 18.1 0.0 0.019 14.5 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 PRP80749.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.9 PRP80749.1 - 0.075 12.5 0.0 0.22 11.0 0.0 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase PGAP1 PF07819.13 PRP80749.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.8 PRP80749.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 PRP80749.1 - 0.17 11.1 0.0 0.72 9.1 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Sec1 PF00995.23 PRP80750.1 - 6.6e-07 28.9 0.5 1.7e-05 24.3 0.3 2.1 2 0 0 2 2 2 2 Sec1 family Clat_adaptor_s PF01217.20 PRP80751.1 - 3.5e-52 176.1 1.5 4e-52 175.9 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.11 PRP80751.1 - 0.075 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) UPF0102 PF02021.17 PRP80751.1 - 0.11 12.8 0.4 21 5.4 0.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family UPF0102 Ribosomal_S19e PF01090.19 PRP80753.1 - 6.3e-56 187.9 0.1 7.2e-56 187.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e C9orf72-like PF15019.6 PRP80754.1 - 1.1e-43 149.6 4.0 1.5e-43 149.2 4.0 1.2 1 0 0 1 1 1 1 C9orf72-like protein family HOOK PF05622.12 PRP80755.1 - 0.15 10.2 0.0 0.19 9.9 0.0 1.0 1 0 0 1 1 1 0 HOOK protein LAG1-DNAbind PF09271.11 PRP80756.1 - 0.0028 18.3 0.2 0.011 16.3 0.2 2.0 1 1 0 1 1 1 1 LAG1, DNA binding AAA_12 PF13087.6 PRP80757.1 - 7.7e-62 208.5 0.0 1.5e-61 207.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PRP80757.1 - 3e-50 171.5 2.6 1e-48 166.4 2.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP80757.1 - 2.2e-11 44.3 0.0 1.3e-10 41.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP80757.1 - 1.7e-08 34.4 0.0 0.00079 19.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 PRP80757.1 - 1.6e-05 24.8 0.2 0.16 11.7 0.0 3.4 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 PRP80757.1 - 0.0012 18.2 0.2 0.0099 15.2 0.1 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 PRP80757.1 - 0.0016 18.4 0.0 0.019 15.0 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 PRP80757.1 - 0.002 18.5 0.1 0.007 16.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.21 PRP80757.1 - 0.0034 17.0 1.1 0.013 15.0 0.1 2.4 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 PRP80757.1 - 0.0077 16.5 0.1 0.22 11.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 PRP80757.1 - 0.0077 16.2 0.1 1.2 9.1 0.0 3.4 4 0 0 4 4 3 1 NACHT domain Rad17 PF03215.15 PRP80757.1 - 0.011 15.6 0.1 1.2 9.1 0.0 3.1 3 0 0 3 3 3 0 Rad17 P-loop domain AAA PF00004.29 PRP80757.1 - 0.017 15.5 0.1 0.099 13.1 0.0 2.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP80757.1 - 0.06 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 PRP80757.1 - 0.069 13.0 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_18 PF13238.6 PRP80757.1 - 0.076 13.6 0.1 0.66 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PRP80757.1 - 0.078 13.1 0.2 0.51 10.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PRP80757.1 - 0.08 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 PRP80757.1 - 0.086 12.3 0.0 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 PRP80757.1 - 0.1 13.0 0.0 0.48 10.8 0.0 2.2 1 0 0 1 1 1 0 RNA helicase UvrD_C PF13361.6 PRP80757.1 - 0.69 9.2 3.8 26 4.0 0.0 3.4 3 1 1 4 4 4 0 UvrD-like helicase C-terminal domain Pkinase_Tyr PF07714.17 PRP80758.1 - 9.2e-35 120.2 0.0 1.5e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80758.1 - 4.2e-27 95.2 0.0 7.2e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP80758.1 - 0.00023 21.6 1.8 0.0011 19.5 1.8 2.3 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Glucodextran_B PF09136.10 PRP80758.1 - 0.1 13.0 7.3 7.1 7.1 4.6 3.1 2 0 0 2 2 2 0 Glucodextranase, domain B TMEM154 PF15102.6 PRP80758.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.3 3 0 0 3 3 3 0 TMEM154 protein family ASC PF00858.24 PRP80759.1 - 6.9e-09 35.2 14.2 1.8e-05 23.9 2.4 3.3 1 1 2 3 3 3 3 Amiloride-sensitive sodium channel Connexin PF00029.19 PRP80759.1 - 0.018 14.8 0.3 0.029 14.1 0.3 1.2 1 0 0 1 1 1 0 Connexin Dynamin_N PF00350.23 PRP80760.1 - 1.3e-11 44.8 0.1 1.9e-10 41.1 0.1 2.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PRP80760.1 - 2.1e-05 24.6 0.0 4.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.32 PRP80761.1 - 1.2e-13 51.3 9.2 0.005 17.6 0.6 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80761.1 - 2.2e-09 37.5 0.1 0.00091 19.5 0.0 4.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 PRP80761.1 - 0.14 12.2 0.0 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region MFS_1 PF07690.16 PRP80763.1 - 5.4e-34 117.7 32.0 5.4e-34 117.7 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EGF_2 PF07974.13 PRP80765.1 - 0.028 14.8 10.2 0.054 13.9 10.2 1.5 1 0 0 1 1 1 0 EGF-like domain Mating_N PF12731.7 PRP80767.1 - 0.019 15.0 0.5 2.1 8.5 0.2 3.1 2 0 0 2 2 2 0 Mating-type protein beta 1 DUF3763 PF12592.8 PRP80767.1 - 0.24 11.5 1.5 3.8 7.6 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) DUF842 PF05811.13 PRP80767.1 - 2.2 8.0 7.7 2.9 7.6 0.0 3.5 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) Mon1 PF03164.14 PRP80768.1 - 1.4e-19 70.5 1.0 1.2e-16 60.9 0.2 2.2 2 0 0 2 2 2 2 Trafficking protein Mon1 Acyl-CoA_dh_1 PF00441.24 PRP80770.1 - 7.2e-39 133.4 0.4 1.6e-38 132.3 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AAA PF00004.29 PRP80770.1 - 5.1e-30 104.6 0.0 1.3e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Acyl-CoA_dh_M PF02770.19 PRP80770.1 - 5.5e-21 74.6 0.0 1.4e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PRP80770.1 - 1.4e-19 70.8 0.0 3.1e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 PRP80770.1 - 3.7e-18 65.4 0.1 1.4e-17 63.6 0.0 2.0 2 0 0 2 2 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 PRP80770.1 - 3.6e-08 33.7 0.3 7.1e-08 32.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AAA_22 PF13401.6 PRP80770.1 - 6.6e-06 26.4 0.1 3.2e-05 24.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP80770.1 - 2e-05 25.2 0.0 4.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PRP80770.1 - 3.6e-05 23.8 0.0 0.00015 21.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 PRP80770.1 - 5.1e-05 23.7 0.1 0.00028 21.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 PRP80770.1 - 0.00052 19.9 0.0 0.0094 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP80770.1 - 0.0015 18.8 0.2 0.0057 17.0 0.0 2.1 2 0 0 2 2 1 1 RNA helicase TsaE PF02367.17 PRP80770.1 - 0.0025 17.8 0.0 0.01 15.8 0.0 2.0 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 PRP80770.1 - 0.0026 17.9 0.0 0.0083 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 PRP80770.1 - 0.003 17.7 0.0 0.0089 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 PRP80770.1 - 0.0031 17.5 0.6 1.5 8.7 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 PRP80770.1 - 0.0048 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 PRP80770.1 - 0.0058 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 PRP80770.1 - 0.0074 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase PduV-EutP PF10662.9 PRP80770.1 - 0.0085 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 PRP80770.1 - 0.012 15.6 0.1 0.03 14.3 0.1 1.7 1 1 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 PRP80770.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 PRP80770.1 - 0.013 16.0 0.0 0.084 13.4 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_5 PF07728.14 PRP80770.1 - 0.015 15.3 0.0 0.048 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PRP80770.1 - 0.019 14.7 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 PRP80770.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 PRP80770.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PRP80770.1 - 0.029 13.9 0.1 1 8.9 0.0 2.3 1 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 PRP80770.1 - 0.034 13.4 0.2 1.1 8.4 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain RuvB_N PF05496.12 PRP80770.1 - 0.037 13.8 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 PRP80770.1 - 0.044 13.5 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 PRP80770.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 PRP80770.1 - 0.06 13.5 0.4 0.15 12.2 0.1 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 PRP80770.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.13 PRP80770.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Rad17 PF03215.15 PRP80770.1 - 0.071 13.0 0.1 0.22 11.4 0.0 1.9 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_17 PF13207.6 PRP80770.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 PRP80770.1 - 0.08 12.2 0.0 0.19 10.9 0.0 1.6 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 PRP80770.1 - 0.094 13.0 0.1 0.41 11.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 PRP80770.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF5313 PF17240.2 PRP80770.1 - 0.22 11.9 0.5 0.67 10.4 0.5 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5313) ATPase PF06745.13 PRP80770.1 - 0.95 8.8 4.5 6.1 6.1 0.0 3.5 3 1 1 4 4 4 0 KaiC DUF1772 PF08592.11 PRP80770.1 - 4.6 7.6 6.3 1.5 9.1 0.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) GFO_IDH_MocA PF01408.22 PRP80771.1 - 9.8e-19 68.3 0.0 1.5e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PRP80771.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 PRP80771.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Y_phosphatase3 PF13350.6 PRP80774.1 - 9.3e-43 146.9 0.2 4.5e-42 144.6 0.2 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 PRP80774.1 - 6.2e-08 32.5 0.0 1.3e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 PRP80774.1 - 6.7e-07 29.0 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 PRP80774.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 PRP80774.1 - 0.18 11.6 0.1 0.42 10.4 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Arm_APC_u3 PF16629.5 PRP80774.1 - 0.52 9.9 6.4 1.3 8.5 3.2 2.3 2 0 0 2 2 2 0 Armadillo-associated region on APC K_trans PF02705.16 PRP80775.1 - 8.4e-188 625.2 19.6 1.1e-187 624.9 19.6 1.1 1 0 0 1 1 1 1 K+ potassium transporter Thaumatin PF00314.17 PRP80777.1 - 6.8e-11 42.2 0.1 1.9e-05 24.4 0.0 2.1 1 1 1 2 2 2 2 Thaumatin family SH2 PF00017.24 PRP80778.1 - 7.2e-10 38.8 0.0 9.1e-06 25.7 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP80778.1 - 2.2e-09 37.9 0.3 3.2e-08 34.2 0.1 2.5 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain IBP39 PF11422.8 PRP80778.1 - 0.014 15.2 0.2 0.028 14.2 0.2 1.5 1 0 0 1 1 1 0 Initiator binding protein 39 kDa MaoC_dehydratas PF01575.19 PRP80780.1 - 9e-08 31.7 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 PRP80780.1 - 0.0031 17.7 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Plk4_PB1 PF18190.1 PRP80780.1 - 0.083 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 RhoGAP PF00620.27 PRP80781.1 - 3.9e-36 124.2 0.0 6.3e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain BAR PF03114.18 PRP80782.1 - 7.6e-10 38.8 4.0 1.5e-09 37.8 4.0 1.5 1 1 0 1 1 1 1 BAR domain FH2 PF02181.23 PRP80782.1 - 0.015 14.5 0.2 0.015 14.5 0.2 1.5 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF4621 PF15414.6 PRP80782.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) Chalcone_N PF18232.1 PRP80784.1 - 0.15 12.5 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Chalcone isomerase N-terminal domain AAA_16 PF13191.6 PRP80785.1 - 1.8e-38 132.6 0.0 7.9e-38 130.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Pkinase PF00069.25 PRP80785.1 - 1.6e-33 116.2 0.0 3.8e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain HATPase_c PF02518.26 PRP80785.1 - 1.4e-25 90.0 0.2 7.7e-25 87.6 0.3 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP80785.1 - 2.2e-23 82.5 0.7 5.6e-23 81.2 0.1 2.1 2 0 0 2 2 1 1 Response regulator receiver domain Pkinase_Tyr PF07714.17 PRP80785.1 - 2.3e-18 66.4 0.0 5.5e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_2 PF13185.6 PRP80785.1 - 7e-09 36.1 0.0 2.3e-08 34.4 0.0 2.0 2 0 0 2 2 1 1 GAF domain HisKA PF00512.25 PRP80785.1 - 1.8e-08 34.3 0.0 5.8e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 PRP80785.1 - 7.8e-08 33.0 0.0 1.5e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 PRP80785.1 - 0.0012 18.7 0.1 0.0031 17.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF815 PF05673.13 PRP80785.1 - 0.0068 15.6 0.0 0.021 14.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TPR_12 PF13424.6 PRP80785.1 - 0.0074 16.6 0.4 0.25 11.7 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat RsgA_GTPase PF03193.16 PRP80785.1 - 0.022 14.7 0.0 0.09 12.7 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 PRP80785.1 - 0.035 13.4 0.0 0.094 12.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Kdo PF06293.14 PRP80785.1 - 0.046 13.1 0.1 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sigma54_activat PF00158.26 PRP80785.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 PRP80785.1 - 0.11 12.6 0.2 6.2 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 PRP80785.1 - 0.13 12.0 3.0 0.6 9.8 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 PRP80785.1 - 0.16 12.2 0.0 4.9 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 PRP80785.1 - 0.18 12.1 0.2 7.5 6.9 0.1 3.2 2 1 0 2 2 2 0 AAA domain TPR_1 PF00515.28 PRP80785.1 - 3.2 7.7 5.1 19 5.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pro_CA PF00484.19 PRP80786.1 - 5.7e-47 159.9 2.1 9.5e-47 159.2 2.1 1.4 1 0 0 1 1 1 1 Carbonic anhydrase CAP PF00188.26 PRP80787.1 - 1.2e-20 74.6 4.1 2.5e-20 73.6 4.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Rtt102p PF09510.10 PRP80787.1 - 0.073 13.3 0.1 0.19 11.9 0.0 1.7 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein Mito_carr PF00153.27 PRP80789.1 - 1.3e-60 201.3 1.6 6.8e-20 70.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SapB_2 PF03489.17 PRP80790.1 - 0.27 11.4 2.8 6.1 7.1 1.4 3.0 2 1 0 2 2 2 0 Saposin-like type B, region 2 Ank_2 PF12796.7 PRP80793.1 - 1.9e-51 172.5 0.0 1.2e-10 41.8 0.0 5.6 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80793.1 - 4.6e-35 119.6 1.9 2e-05 25.0 0.0 9.0 5 1 4 9 9 9 7 Ankyrin repeats (many copies) CH PF00307.31 PRP80793.1 - 6.8e-32 109.9 0.1 9.5e-19 67.6 0.7 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain Filamin PF00630.19 PRP80793.1 - 5.5e-26 91.4 8.8 9.9e-05 23.1 0.0 9.6 8 2 1 9 9 9 6 Filamin/ABP280 repeat Ank_5 PF13857.6 PRP80793.1 - 1.5e-20 73.0 0.7 0.024 15.0 0.0 10.1 4 3 6 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP80793.1 - 1.1e-18 66.7 0.0 1.3 9.6 0.0 11.7 13 0 0 13 13 13 3 Ankyrin repeat Ank_3 PF13606.6 PRP80793.1 - 3.1e-17 60.9 0.0 4.3 8.2 0.0 10.4 11 0 0 11 11 11 4 Ankyrin repeat Methyltransf_24 PF13578.6 PRP80793.1 - 1 10.4 4.9 2.4e+02 2.8 0.1 4.8 4 1 1 5 5 5 0 Methyltransferase domain DUF4360 PF14273.6 PRP80795.1 - 0.022 14.7 1.6 0.031 14.2 0.4 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4360) YceI PF04264.13 PRP80795.1 - 0.14 12.8 0.3 0.25 11.9 0.3 1.7 1 1 0 1 1 1 0 YceI-like domain BTB PF00651.31 PRP80797.1 - 2.4e-19 69.6 0.1 1.4e-13 51.0 0.2 3.3 3 0 0 3 3 3 2 BTB/POZ domain BACK PF07707.15 PRP80797.1 - 8.8e-08 32.2 0.4 3.8e-06 26.9 0.0 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch DUF3579 PF12112.8 PRP80797.1 - 0.028 15.0 0.4 0.15 12.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3579) Prophage_tail PF06605.11 PRP80797.1 - 0.19 10.9 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Prophage endopeptidase tail EGF_2 PF07974.13 PRP80798.1 - 0.019 15.3 4.8 0.037 14.4 4.8 1.4 1 0 0 1 1 1 0 EGF-like domain Mntp PF02659.15 PRP80798.1 - 0.08 12.7 6.6 0.019 14.8 2.1 2.1 2 0 0 2 2 2 0 Putative manganese efflux pump PsiE PF06146.12 PRP80799.1 - 0.14 12.5 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphate-starvation-inducible E PHD PF00628.29 PRP80801.1 - 0.00031 20.6 8.7 0.0006 19.6 8.7 1.5 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 PRP80801.1 - 0.023 15.0 12.7 0.1 13.0 7.6 2.4 2 0 0 2 2 2 0 C1 domain FAM195 PF14799.6 PRP80801.1 - 0.047 14.0 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 FAM195 family C1_1 PF00130.22 PRP80801.1 - 0.15 12.0 13.5 0.095 12.6 10.9 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Clathrin PF00637.20 PRP80802.1 - 2.9e-193 633.5 40.8 7.2e-32 110.2 2.2 8.1 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 PRP80802.1 - 7.4e-33 112.3 1.1 7.4e-33 112.3 1.1 3.8 4 0 0 4 4 4 1 Clathrin-H-link TPR_14 PF13428.6 PRP80802.1 - 1e-08 35.3 1.0 2.3 9.3 0.0 8.3 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP80802.1 - 1.3e-07 31.2 3.4 2.5 8.3 0.1 7.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP80802.1 - 3.4e-05 23.7 3.7 0.26 11.6 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP80802.1 - 0.0021 17.8 0.7 4.9 7.1 0.2 4.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP80802.1 - 0.034 14.3 8.1 1.5 9.1 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 PRP80802.1 - 0.038 14.0 0.2 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_12 PF13424.6 PRP80802.1 - 0.05 13.9 1.1 6.6 7.1 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat YppF PF14178.6 PRP80802.1 - 0.21 11.5 3.0 9.8 6.1 0.4 3.4 2 0 0 2 2 2 0 YppF-like protein zf-CHY PF05495.12 PRP80804.1 - 1.6e-10 41.3 11.7 1.6e-10 41.3 11.7 4.5 3 1 2 5 5 5 1 CHY zinc finger RWD PF05773.22 PRP80804.1 - 8e-09 35.8 0.6 2.2e-08 34.4 0.1 2.0 2 0 0 2 2 2 1 RWD domain LMBR1 PF04791.16 PRP80804.1 - 1.5 7.7 2.5 2.6 6.8 2.5 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein 4HBT_2 PF13279.6 PRP80805.1 - 4.2e-13 49.9 0.3 8.4e-13 48.9 0.0 1.6 2 0 0 2 2 2 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 PRP80805.1 - 0.07 12.4 0.4 0.13 11.5 0.4 1.4 1 0 0 1 1 1 0 Acyl-ACP thioesterase Bac_GDH PF05088.12 PRP80806.1 - 0.004 14.8 0.2 0.005 14.4 0.2 1.1 1 0 0 1 1 1 1 Bacterial NAD-glutamate dehydrogenase DDE_Tnp_1_7 PF13843.6 PRP80808.1 - 8e-06 25.4 0.0 0.00019 20.9 0.0 2.2 1 1 1 2 2 2 2 Transposase IS4 DDE_Tnp_1_7 PF13843.6 PRP80809.1 - 0.0055 16.1 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF608 PF04685.13 PRP80809.1 - 0.06 12.5 0.1 0.06 12.5 0.1 1.1 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region SdrD_B PF17210.3 PRP80811.1 - 5 7.4 24.0 0.83 9.9 1.9 4.1 4 0 0 4 4 4 0 SdrD B-like domain ABC_tran PF00005.27 PRP80817.1 - 5.3e-53 179.2 0.0 2.2e-26 93.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC2_membrane_3 PF12698.7 PRP80817.1 - 2.1e-42 145.5 56.2 5.4e-24 85.0 25.2 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 PRP80817.1 - 4.4e-22 79.3 1.2 1.3e-07 31.7 0.0 4.4 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PRP80817.1 - 1.1e-05 25.3 0.0 1.6 8.4 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 PRP80817.1 - 8.7e-05 23.1 0.2 0.063 13.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 PRP80817.1 - 0.00012 21.6 0.0 0.84 9.0 0.0 3.9 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 PRP80817.1 - 0.0024 17.6 0.3 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PRP80817.1 - 0.0045 16.3 0.0 0.67 9.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 PRP80817.1 - 0.0096 16.2 0.3 1.9 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PRP80817.1 - 0.018 14.8 0.6 5.7 6.6 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein SRP54 PF00448.22 PRP80817.1 - 0.024 14.3 1.9 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 PRP80817.1 - 0.027 14.8 0.1 5.3 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 PRP80817.1 - 0.03 14.0 0.1 4 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP80817.1 - 0.033 13.9 0.6 7.7 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_27 PF13514.6 PRP80817.1 - 0.036 13.7 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 PRP80817.1 - 0.037 14.3 0.0 3.1 8.1 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF4800 PF16057.5 PRP80817.1 - 0.097 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) AAA_19 PF13245.6 PRP80817.1 - 0.16 12.3 1.1 22 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PRP80817.1 - 0.52 10.7 2.8 3 8.3 0.2 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DSPc PF00782.20 PRP80818.1 - 3.5e-31 107.8 0.0 5e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.22 PRP80818.1 - 1.8e-18 66.1 0.0 3.4e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Init_tRNA_PT PF04179.12 PRP80818.1 - 0.0031 17.8 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 PRP80818.1 - 0.0037 16.9 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PRP80818.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Sugar_tr PF00083.24 PRP80820.1 - 2.7e-28 99.0 27.2 1.5e-17 63.6 6.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PRP80820.1 - 2.8e-24 85.7 57.0 4.2e-23 81.9 32.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PRP80820.1 - 1.3e-06 27.3 13.2 0.0028 16.3 1.7 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein UPF0180 PF03698.13 PRP80820.1 - 0.22 11.7 0.1 0.42 10.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) adh_short_C2 PF13561.6 PRP80821.1 - 2e-69 233.7 1.6 2.4e-69 233.4 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP80821.1 - 2.5e-50 170.7 1.5 3.2e-50 170.3 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP80821.1 - 7.9e-09 35.7 0.7 1.2e-08 35.0 0.7 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 PRP80821.1 - 0.027 15.1 0.1 0.059 14.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase_Tyr PF07714.17 PRP80822.1 - 1.9e-43 148.6 0.0 2.9e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80822.1 - 2.1e-25 89.6 0.0 3.8e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP80822.1 - 3.2e-10 40.4 4.5 1.1e-09 38.7 4.5 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif DUF4957 PF16318.5 PRP80822.1 - 0.0043 17.0 1.2 0.0043 17.0 1.2 5.1 4 2 2 6 6 6 3 Domain of unknown function (DUF4957) YajC PF02699.15 PRP80822.1 - 0.011 15.6 0.1 0.027 14.4 0.1 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit Mid2 PF04478.12 PRP80822.1 - 0.05 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Kinase-like PF14531.6 PRP80822.1 - 0.083 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Insulin_TMD PF17870.1 PRP80822.1 - 0.16 12.0 0.8 0.49 10.5 0.8 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4336 PF14234.6 PRP80823.1 - 1.6e-08 34.1 0.0 0.00027 20.2 0.0 2.7 1 1 0 2 2 2 2 Domain of unknown function (DUF4336) Acetyltransf_3 PF13302.7 PRP80824.1 - 1.7e-11 45.0 0.0 2.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP80824.1 - 8.1e-07 29.3 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Dynamin_M PF01031.20 PRP80825.1 - 4.6e-91 305.0 0.1 4.6e-91 305.0 0.1 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 PRP80825.1 - 3.6e-51 173.6 0.1 1.2e-50 171.8 0.0 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 PRP80825.1 - 3.6e-26 91.1 7.6 3.6e-26 91.1 7.6 2.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 PRP80825.1 - 8.7e-06 25.8 0.4 0.0011 19.1 0.1 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF2076 PF09849.9 PRP80825.1 - 0.0022 18.1 0.3 0.0045 17.1 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) AAA_28 PF13521.6 PRP80825.1 - 0.037 14.3 0.2 0.095 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain CdiI_3 PF18616.1 PRP80825.1 - 0.057 13.3 0.7 9.1 6.2 0.0 3.1 3 0 0 3 3 3 0 CDI immunity proteins Acetyltransf_4 PF13420.7 PRP80826.1 - 6.5e-07 29.6 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP80826.1 - 0.00033 20.9 0.1 0.00073 19.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PRP80826.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 PRP80826.1 - 0.035 14.8 0.0 0.072 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP80826.1 - 0.036 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 PRP80827.1 - 6.9e-44 150.2 24.0 6.9e-44 150.2 24.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 PRP80827.1 - 2.3e-11 42.7 12.7 2.4e-06 26.2 0.2 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 PRP80827.1 - 3.2e-05 22.5 15.9 0.0002 19.9 15.9 1.9 1 1 0 1 1 1 1 Transmembrane secretion effector Gly-zipper_Omp PF13488.6 PRP80827.1 - 0.0032 17.4 7.6 0.24 11.4 1.0 2.7 2 0 0 2 2 2 2 Glycine zipper Gaa1 PF04114.14 PRP80827.1 - 0.24 10.4 3.5 0.42 9.6 0.4 2.1 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component 2OG-FeII_Oxy_3 PF13640.6 PRP80828.1 - 3.9e-12 46.9 0.0 7.3e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPT PF03151.16 PRP80828.1 - 5.8e-12 45.6 17.7 7.8e-12 45.1 17.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PRP80828.1 - 1e-07 32.2 10.0 1e-07 32.2 10.0 2.3 2 0 0 2 2 2 1 EamA-like transporter family PhyH PF05721.13 PRP80828.1 - 0.068 13.4 0.0 0.26 11.5 0.0 1.8 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) BolA PF01722.18 PRP80829.1 - 3.5e-27 94.5 0.5 9.9e-27 93.0 0.1 2.0 2 1 0 2 2 2 1 BolA-like protein STAR_dimer PF16544.5 PRP80829.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein NAD_Gly3P_dh_C PF07479.14 PRP80830.1 - 1.1e-46 158.6 0.1 2.9e-46 157.3 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 PRP80830.1 - 3.6e-45 153.8 0.0 6.2e-45 153.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 PRP80830.1 - 0.0024 18.4 2.6 0.038 14.6 1.6 2.8 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ABC_transp_aux PF09822.9 PRP80830.1 - 0.0033 16.9 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system IlvN PF07991.12 PRP80830.1 - 0.15 11.6 0.7 16 5.1 0.2 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain CLU PF13236.6 PRP80831.1 - 5.1e-46 157.3 0.0 9.5e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP80831.1 - 0.0029 17.7 1.3 0.0062 16.6 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 Nup160 PF11715.8 PRP80832.1 - 4.8e-33 114.6 0.3 8.6e-33 113.8 0.3 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Pkinase_Tyr PF07714.17 PRP80833.1 - 1.3e-74 250.8 0.0 2.1e-74 250.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80833.1 - 6.2e-49 166.7 0.0 1.1e-48 165.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Chitin_bind_1 PF00187.19 PRP80833.1 - 6.5e-39 132.1 172.2 1.7e-07 31.6 21.9 7.9 7 0 0 7 7 7 7 Chitin recognition protein Glyco_hydro_18 PF00704.28 PRP80833.1 - 4.9e-37 128.3 5.7 8.8e-37 127.5 5.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase_fungal PF17667.1 PRP80833.1 - 0.015 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PRP80833.1 - 0.041 13.2 0.1 0.1 11.9 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family L51_S25_CI-B8 PF05047.16 PRP80833.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ytca PF17090.5 PRP80833.1 - 0.18 12.3 1.0 0.5 10.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family Adeno_E1B_55K PF01696.17 PRP80834.1 - 6.2 5.4 25.4 0.026 13.2 1.9 4.9 3 2 1 6 6 6 0 Adenovirus EB1 55K protein / large t-antigen ETC_C1_NDUFA5 PF04716.14 PRP80835.1 - 0.18 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 ETC complex I subunit conserved region CD20 PF04103.15 PRP80837.1 - 0.0031 17.6 0.1 0.0031 17.6 0.1 1.0 1 0 0 1 1 1 1 CD20-like family Peptidase_C12 PF01088.21 PRP80840.1 - 3.3e-62 210.0 0.0 3.7e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pur_ac_phosph_N PF16656.5 PRP80841.1 - 1.4e-21 76.9 1.6 1.4e-21 76.9 1.6 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 PRP80841.1 - 1.9e-21 77.5 1.0 3.4e-21 76.7 1.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PRP80841.1 - 6.5e-12 46.1 0.6 6.5e-12 46.1 0.6 2.9 2 2 1 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 PRP80841.1 - 9.5e-06 25.9 0.0 5.7e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain adh_short_C2 PF13561.6 PRP80843.1 - 2.6e-61 207.2 0.0 3.6e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP80843.1 - 1.9e-47 161.3 0.1 2.8e-47 160.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP80843.1 - 9.2e-12 45.2 0.1 1.4e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 KR domain PPR_3 PF13812.6 PRP80844.1 - 9.2e-18 64.1 1.0 3.1e-08 33.6 0.1 4.6 2 2 2 4 4 4 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 PRP80844.1 - 6.6e-13 48.6 2.3 3.8e-10 39.8 0.3 4.1 2 2 2 4 4 4 2 PPR repeat family PPR PF01535.20 PRP80844.1 - 4.6e-10 39.1 7.1 0.0026 17.9 0.2 5.6 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 PRP80844.1 - 3.3e-07 29.9 0.1 0.0094 15.3 0.0 3.7 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP80844.1 - 7.6e-05 22.3 0.0 0.1 12.3 0.0 2.7 2 0 0 2 2 2 2 PPR repeat SprT-like PF10263.9 PRP80845.1 - 3.7e-24 84.7 0.0 1e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.19 PRP80845.1 - 9.6e-05 22.7 0.1 9.6e-05 22.7 0.1 5.5 3 1 1 4 4 4 1 HMG (high mobility group) box YABBY PF04690.13 PRP80845.1 - 0.0052 17.4 0.0 0.0052 17.4 0.0 4.2 3 1 0 3 3 3 1 YABBY protein Zn_ribbon_SprT PF17283.2 PRP80845.1 - 0.0086 16.0 0.3 0.019 14.8 0.3 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain MBOAT_2 PF13813.6 PRP80846.1 - 3.2e-12 46.6 0.8 1.1e-11 44.8 0.7 2.0 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family AIRS_C PF02769.22 PRP80848.1 - 7.3e-21 74.9 0.0 1.3e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 PRP80848.1 - 1.2e-09 38.7 0.0 2.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain COX6B PF02297.17 PRP80849.1 - 0.00047 20.3 3.2 0.00069 19.8 3.2 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.13 PRP80849.1 - 0.032 14.0 2.2 0.36 10.6 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 PRP80849.1 - 0.091 12.9 1.7 0.75 10.0 1.7 2.1 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 PRP80849.1 - 0.12 12.4 2.3 4.9 7.3 0.1 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 PRP80849.1 - 0.18 11.9 4.1 1.3 9.1 4.1 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CDC50 PF03381.15 PRP80850.1 - 3.8e-86 289.1 0.2 5.3e-86 288.6 0.2 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Vps54_N PF10475.9 PRP80852.1 - 3.5e-63 213.6 5.8 6.5e-63 212.7 5.8 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 PRP80852.1 - 1.1e-46 159.5 0.1 3.1e-46 158.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Pkinase PF00069.25 PRP80852.1 - 3.5e-42 144.6 0.0 5.2e-41 140.7 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80852.1 - 1.6e-41 142.3 0.1 7.2e-26 91.0 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase SH2 PF00017.24 PRP80852.1 - 2.3e-07 30.8 0.0 7.8e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Kdo PF06293.14 PRP80852.1 - 2.2e-05 23.9 0.1 8.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP80852.1 - 0.0069 15.2 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Sec8_exocyst PF04048.14 PRP80852.1 - 0.018 15.0 5.2 0.054 13.4 2.6 2.8 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain FTA2 PF13095.6 PRP80852.1 - 0.022 14.4 2.5 7.8 6.0 0.0 4.2 4 0 0 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 CS PF04969.16 PRP80857.1 - 5.8e-09 36.9 0.0 9.9e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 CS domain Coprogen_oxidas PF01218.18 PRP80858.1 - 3.7e-86 288.5 0.5 1.9e-50 171.3 0.7 2.8 2 1 0 2 2 2 2 Coproporphyrinogen III oxidase GTP_EFTU PF00009.27 PRP80862.1 - 2.4e-34 118.6 0.0 1.1e-25 90.4 0.0 2.9 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PRP80862.1 - 6.1e-20 71.1 0.0 1.5e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PRP80862.1 - 1.4e-11 44.6 0.1 9.3e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 PRP80862.1 - 9.4e-08 31.9 0.0 3.1e-06 27.0 0.1 3.1 2 1 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.6 PRP80862.1 - 6.3e-07 29.4 0.1 2.4e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II DUF4795 PF16043.5 PRP80862.1 - 0.038 13.6 0.0 0.038 13.6 0.0 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4795) Tmemb_185A PF10269.9 PRP80864.1 - 0.004 16.9 32.2 0.017 14.8 30.1 2.5 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein CRPA PF05745.11 PRP80864.1 - 3.5 7.6 13.2 0.29 11.1 6.5 2.5 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) SirB PF04247.12 PRP80864.1 - 7.7 6.6 19.0 0.27 11.3 4.3 3.1 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB Pkinase PF00069.25 PRP80865.1 - 1.6e-45 155.5 0.1 5.7e-30 104.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80865.1 - 2.3e-23 82.8 0.0 6.4e-23 81.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 PRP80865.1 - 1e-11 44.9 0.0 2.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 APH PF01636.23 PRP80865.1 - 2.2e-05 24.5 0.0 0.13 12.2 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP80865.1 - 0.0086 15.4 0.0 0.09 12.1 0.0 2.6 3 1 0 3 3 3 1 Kinase-like ACP_syn_III_C PF08541.10 PRP80865.1 - 0.21 11.8 0.4 0.58 10.4 0.4 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2999 PF11212.8 PRP80865.1 - 0.35 11.2 3.5 9.6 6.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) VWA PF00092.28 PRP80866.1 - 4.7e-09 36.7 0.0 8.9e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.23 PRP80866.1 - 6.7e-07 29.0 0.1 7e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 Ubiquitin family VWA_2 PF13519.6 PRP80866.1 - 5.1e-06 27.1 0.0 9.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Pro-kuma_activ PF09286.11 PRP80870.1 - 3.5e-31 108.4 0.0 7e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP80870.1 - 2.7e-06 26.9 0.1 5.2e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Subtilase family RINT1_TIP1 PF04437.13 PRP80872.1 - 2.5e-69 234.5 11.7 2.5e-69 234.5 11.7 3.9 3 2 0 3 3 3 1 RINT-1 / TIP-1 family ZapB PF06005.12 PRP80872.1 - 0.012 16.1 2.7 0.012 16.1 2.7 2.7 3 0 0 3 3 3 0 Cell division protein ZapB DNA_repr_REX1B PF14966.6 PRP80872.1 - 2.9 8.6 9.9 9.4 7.0 1.8 4.4 3 1 1 4 4 4 0 DNA repair REX1-B SRPRB PF09439.10 PRP80873.1 - 5.4e-36 123.7 0.0 6.7e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 PRP80873.1 - 4e-16 59.0 0.0 5.4e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PRP80873.1 - 1.1e-08 34.9 0.1 1.6e-08 34.4 0.1 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP80873.1 - 9.3e-08 32.3 0.0 1.7e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PRP80873.1 - 2.2e-07 31.0 0.1 3.8e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PRP80873.1 - 3.4e-06 27.2 0.2 8.6e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 PRP80873.1 - 4.9e-06 26.2 0.5 3.2e-05 23.6 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP80873.1 - 5.5e-05 22.6 0.1 7.3e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 PRP80873.1 - 6.8e-05 22.2 1.5 0.00071 18.8 0.3 2.4 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 PRP80873.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein KTI12 PF08433.10 PRP80873.1 - 0.0013 18.3 0.2 0.03 13.8 0.1 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 FeoB_N PF02421.18 PRP80873.1 - 0.0041 16.7 0.1 0.014 14.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP80873.1 - 0.0069 16.3 0.2 1.2 9.1 0.1 2.7 2 1 0 2 2 2 1 RsgA GTPase PEPCK_ATP PF01293.20 PRP80873.1 - 0.026 13.2 0.4 0.066 11.9 0.1 1.6 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxykinase Kinesin PF00225.23 PRP80875.1 - 8.5e-100 333.9 5.4 8.5e-100 333.9 5.4 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PRP80875.1 - 1.6e-26 93.0 1.2 2.8e-26 92.3 0.1 2.0 2 0 0 2 2 2 1 Microtubule binding HR1 PF02185.16 PRP80875.1 - 0.026 14.6 0.4 0.14 12.3 0.4 2.4 1 0 0 1 1 1 0 Hr1 repeat AAA_16 PF13191.6 PRP80875.1 - 0.046 14.1 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 PRP80875.1 - 0.1 12.3 0.2 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 PRP80875.1 - 8.5 6.3 9.4 0.67 9.9 0.8 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit MRP-L20 PF12824.7 PRP80876.1 - 4.4e-09 36.7 6.2 6.1e-09 36.2 5.8 1.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.12 PRP80876.1 - 0.04 13.9 0.1 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 HTH domain RRT14 PF17075.5 PRP80876.1 - 1.5 8.9 16.2 2.7 8.1 4.6 2.0 1 1 1 2 2 2 0 Regular of rDNA transcription protein 14 Methyltransf_16 PF10294.9 PRP80877.1 - 3.2e-21 75.9 0.0 4.4e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 PRP80877.1 - 0.00043 20.9 0.0 0.0012 19.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PRP80877.1 - 0.0026 17.3 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 PRP80877.1 - 0.004 17.8 0.1 0.021 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP80877.1 - 0.02 15.6 0.0 0.035 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PhnI PF05861.12 PRP80878.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Kre28 PF17097.5 PRP80879.1 - 0.029 13.3 0.1 0.032 13.2 0.1 1.1 1 0 0 1 1 1 0 Spindle pole body component rve PF00665.26 PRP80879.1 - 0.03 14.5 0.0 0.062 13.5 0.0 1.6 1 1 1 2 2 2 0 Integrase core domain PPIP5K2_N PF18086.1 PRP80883.1 - 0.3 11.2 1.1 2.5 8.3 0.1 2.1 2 0 0 2 2 2 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain PTPRCAP PF15713.5 PRP80883.1 - 4.6 7.5 5.9 5.4 7.3 1.2 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated ABG_transport PF03806.13 PRP80884.1 - 0.063 11.5 0.0 0.081 11.1 0.0 1.1 1 0 0 1 1 1 0 AbgT putative transporter family IBR PF01485.21 PRP80886.1 - 1.8e-06 28.1 8.7 1.8e-06 28.1 8.7 3.9 3 2 0 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PRP80886.1 - 4.3e-06 27.0 6.7 4.3e-06 27.0 6.7 4.1 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 PRP80886.1 - 0.00034 20.6 6.5 0.00034 20.6 6.5 4.0 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 PRP80886.1 - 0.00069 19.3 8.8 0.0044 16.7 8.8 2.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PRP80886.1 - 0.0013 18.6 7.1 0.0013 18.6 7.1 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP80886.1 - 0.0018 18.1 7.0 0.0018 18.1 7.0 4.8 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP80886.1 - 0.0078 16.2 6.4 0.0078 16.2 6.4 4.2 4 1 0 4 4 4 1 zinc-RING finger domain Scm3 PF10384.9 PRP80886.1 - 0.031 14.0 0.1 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 Centromere protein Scm3 PP2C_2 PF13672.6 PRP80887.1 - 0.0016 18.1 0.0 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Peptidase_S49_N PF08496.10 PRP80887.1 - 0.11 12.6 3.4 0.22 11.6 3.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Swi5 PF07061.11 PRP80887.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 Swi5 4HBT PF03061.22 PRP80888.1 - 1.5e-06 28.4 0.0 2.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DNA_methylase PF00145.17 PRP80891.1 - 6.3e-52 177.0 0.0 7.7e-39 134.0 0.0 3.2 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase Chromo PF00385.24 PRP80891.1 - 1e-19 70.1 3.9 2.5e-11 43.3 0.3 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain BAH PF01426.18 PRP80891.1 - 1.7e-14 53.7 0.1 4e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 BAH domain Cons_hypoth95 PF03602.15 PRP80891.1 - 0.0026 17.4 0.0 0.0078 15.9 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Opy2 PF09463.10 PRP80892.1 - 3.5e-16 59.2 74.5 5.8e-07 29.7 20.4 5.4 5 1 0 5 5 5 3 Opy2 protein RicinB_lectin_2 PF14200.6 PRP80893.1 - 2.7e-07 31.2 0.1 0.0061 17.3 0.2 2.9 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Branch PF02485.21 PRP80895.1 - 2.2e-12 47.0 3.0 3.9e-12 46.2 3.0 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RicinB_lectin_2 PF14200.6 PRP80895.1 - 0.00019 22.1 1.2 0.028 15.1 0.1 2.5 1 1 2 3 3 3 2 Ricin-type beta-trefoil lectin domain-like DUF1700 PF08006.11 PRP80895.1 - 0.18 11.4 1.9 0.32 10.5 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) SgrT PF15894.5 PRP80895.1 - 0.35 10.9 2.8 15 5.7 0.1 2.6 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT Na_Ala_symp PF01235.17 PRP80895.1 - 1.4 8.2 4.8 2 7.6 4.8 1.1 1 0 0 1 1 1 0 Sodium:alanine symporter family Stomagen PF16851.5 PRP80895.1 - 2 8.5 6.4 1.2 9.2 2.6 2.2 2 0 0 2 2 2 0 Stomagen Proteasome PF00227.26 PRP80896.1 - 4.7e-35 120.8 0.4 5.5e-35 120.6 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2121 PF09894.9 PRP80896.1 - 0.11 12.0 0.3 1.6 8.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) SET PF00856.28 PRP80898.1 - 5.6e-10 39.9 0.1 4.3e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 SET domain Ribosomal_S10 PF00338.22 PRP80899.1 - 1e-15 57.7 0.0 1.5e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-MYND PF01753.18 PRP80900.1 - 2.8e-08 33.7 19.0 2.8e-08 33.7 19.0 2.2 2 0 0 2 2 2 1 MYND finger DUF2690 PF10901.8 PRP80900.1 - 0.31 11.4 2.6 0.93 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2690) zf-HIT PF04438.16 PRP80900.1 - 0.38 10.7 9.8 1.1 9.2 9.8 1.9 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 PRP80900.1 - 0.81 10.0 11.6 3.1 8.2 11.6 2.1 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF2407_C PF13373.6 PRP80901.1 - 7.2e-21 74.8 0.3 9.7e-21 74.4 0.3 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 PRP80901.1 - 2.2e-13 49.7 0.0 3.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP80901.1 - 3.2e-06 26.9 0.0 6.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PRP80901.1 - 0.00023 21.7 0.1 0.0028 18.2 0.1 2.2 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP80901.1 - 0.00091 19.3 0.0 0.0024 17.9 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PRP80901.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain GATase_4 PF13230.6 PRP80902.1 - 5.3e-14 51.8 0.0 8.3e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 PRP80902.1 - 4.4e-12 46.4 0.0 7.9e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Syntaxin-18_N PF10496.9 PRP80902.1 - 0.04 14.2 0.5 0.073 13.3 0.5 1.4 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus GATase_7 PF13537.6 PRP80902.1 - 0.073 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain EIIBC-GUT_N PF03612.14 PRP80902.1 - 0.11 12.2 0.9 0.17 11.6 0.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Orf78 PF06024.12 PRP80902.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_S49_N PF08496.10 PRP80902.1 - 0.19 11.7 2.5 0.34 10.9 2.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1682 PF07946.14 PRP80902.1 - 7.5 5.7 13.9 14 4.8 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3883 PF13020.6 PRP80904.1 - 3.6e-06 26.9 1.4 4.7e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) CAP_C PF08603.11 PRP80906.1 - 8.5e-31 106.7 3.6 1.7e-30 105.7 3.6 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 PRP80906.1 - 0.03 14.1 1.6 0.082 12.6 1.2 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor C G-patch PF01585.23 PRP80907.1 - 6.4e-13 48.4 1.6 6.4e-13 48.4 1.6 1.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 PRP80907.1 - 1.4e-06 28.3 1.0 1.4e-06 28.3 1.0 1.7 2 0 0 2 2 2 1 G-patch domain DUF1677 PF07911.13 PRP80907.1 - 0.042 14.2 0.2 0.08 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) zf_UBZ PF18439.1 PRP80907.1 - 0.059 13.0 1.8 0.1 12.2 1.8 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Fucose_iso_N2 PF07882.12 PRP80907.1 - 0.085 12.4 0.3 0.12 11.9 0.3 1.2 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain DUF1682 PF07946.14 PRP80908.1 - 0.15 11.2 10.7 0.035 13.3 7.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DUF4604 PF15377.6 PRP80908.1 - 0.48 10.8 15.2 1 9.8 15.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) VIR_N PF15912.5 PRP80908.1 - 0.75 9.3 12.2 1.4 8.5 12.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Presenilin PF01080.17 PRP80908.1 - 2.3 6.9 3.9 3.4 6.3 3.9 1.2 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 PRP80908.1 - 2.9 7.2 15.4 5.1 6.4 15.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RR_TM4-6 PF06459.12 PRP80908.1 - 3.3 7.5 11.7 5.7 6.7 11.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleo_P87 PF07267.11 PRP80908.1 - 3.7 6.3 7.9 5.4 5.7 7.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP_sp32 PF07222.12 PRP80908.1 - 4.6 6.6 7.7 7.5 5.9 7.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Zip PF02535.22 PRP80908.1 - 4.8 6.3 4.8 4.4 6.4 3.6 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4746 PF15928.5 PRP80908.1 - 6.3 6.1 14.4 10 5.5 14.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EF_TS PF00889.19 PRP80909.1 - 4e-37 127.9 0.0 5.5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor TS Ponericin PF07442.11 PRP80909.1 - 0.022 14.8 6.6 0.022 14.8 6.6 2.2 2 0 0 2 2 2 0 Ponericin DUF440 PF04269.12 PRP80909.1 - 0.025 14.9 0.7 0.33 11.2 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF440 Cob_adeno_trans PF01923.18 PRP80910.1 - 7.5e-60 201.8 0.0 9e-60 201.5 0.0 1.1 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Hormone_3 PF00159.18 PRP80910.1 - 0.012 15.6 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide DUF1912 PF08930.10 PRP80910.1 - 0.051 13.7 1.0 0.13 12.4 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1912) Utp14 PF04615.13 PRP80910.1 - 0.097 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Utp14 protein Ank_2 PF12796.7 PRP80911.1 - 3.4e-27 94.9 0.0 0.00023 21.7 0.0 6.7 4 2 1 6 6 6 5 Ankyrin repeats (3 copies) Rgp1 PF08737.10 PRP80911.1 - 1.7e-24 86.8 0.3 9.5e-16 58.0 0.0 2.2 1 1 1 2 2 2 2 Rgp1 Ank_4 PF13637.6 PRP80911.1 - 3.2e-23 81.8 6.6 0.044 14.4 0.0 10.6 5 3 8 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80911.1 - 4e-14 51.3 2.5 7.7 7.5 0.0 12.3 14 0 0 14 14 14 2 Ankyrin repeat Ank_5 PF13857.6 PRP80911.1 - 8.3e-13 48.3 6.7 2.3 8.6 0.1 10.6 8 4 5 13 13 13 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP80911.1 - 3.7e-11 42.9 12.8 5.1 7.7 0.0 12.8 15 0 0 15 15 15 1 Ankyrin repeat Arrestin_N PF00339.29 PRP80911.1 - 0.0029 17.6 0.2 0.012 15.7 0.1 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PRP80911.1 - 0.008 16.6 0.1 5.2 7.5 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain RabGAP-TBC PF00566.18 PRP80913.1 - 2.5e-49 167.8 1.1 2.5e-49 167.8 1.1 3.0 4 0 0 4 4 4 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 PRP80913.1 - 0.082 12.9 0.4 9.6 6.4 0.1 3.1 2 0 0 2 2 2 0 EF-hand domain Phage_hub_GP28 PF11110.8 PRP80913.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Baseplate hub distal subunit Vps51 PF08700.11 PRP80913.1 - 0.12 12.4 1.3 0.38 10.9 1.3 1.8 1 0 0 1 1 1 0 Vps51/Vps67 EF-hand_7 PF13499.6 PRP80913.1 - 0.16 12.4 9.1 0.55 10.7 1.4 3.3 2 1 0 2 2 2 0 EF-hand domain pair Rtt106 PF08512.12 PRP80914.1 - 5.4e-27 94.0 0.6 7.5e-25 87.2 0.1 3.1 3 0 0 3 3 3 1 Histone chaperone Rttp106-like POB3_N PF17292.2 PRP80914.1 - 6.8e-23 80.9 0.0 1.7e-19 70.0 0.0 2.6 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 PRP80914.1 - 8.9e-22 76.8 0.2 1.4e-20 72.9 0.0 3.0 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) AMP-binding PF00501.28 PRP80915.1 - 1.8e-102 343.1 0.1 2.5e-102 342.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP80915.1 - 0.004 18.1 0.1 0.016 16.2 0.1 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Elf1 PF05129.13 PRP80916.1 - 8.2e-28 96.3 0.5 9.2e-28 96.1 0.5 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.6 PRP80916.1 - 0.0036 17.7 0.4 0.57 10.7 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double domain Lar_restr_allev PF14354.6 PRP80916.1 - 0.0048 17.2 0.5 0.0066 16.8 0.5 1.4 1 0 0 1 1 1 1 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.6 PRP80916.1 - 0.035 14.0 1.2 0.063 13.2 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Rubredoxin PF00301.20 PRP80916.1 - 0.042 13.9 1.0 0.2 11.7 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin zf-CHY PF05495.12 PRP80916.1 - 0.055 14.0 0.9 0.15 12.5 0.3 1.9 2 0 0 2 2 2 0 CHY zinc finger zf-Di19 PF05605.12 PRP80916.1 - 0.18 12.1 4.1 4.6 7.6 4.1 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Mito_carr PF00153.27 PRP80917.1 - 2.4e-25 88.3 0.1 2.3e-08 33.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0004 PF00919.20 PRP80919.1 - 1.9e-29 101.6 0.3 3.6e-29 100.7 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 PRP80919.1 - 8.3e-28 97.8 0.0 2e-27 96.6 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 PRP80919.1 - 9.9e-11 41.5 0.4 2.4e-10 40.3 0.4 1.7 1 0 0 1 1 1 1 TRAM domain TRAM_2 PF18693.1 PRP80919.1 - 0.008 16.3 0.1 0.025 14.8 0.1 1.9 1 0 0 1 1 1 1 TRAM domain RNase_PH PF01138.21 PRP80920.1 - 6e-37 127.1 0.2 9.7e-37 126.4 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PRP80920.1 - 8e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ank_2 PF12796.7 PRP80920.1 - 0.003 18.1 0.0 0.011 16.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box-like PF12937.7 PRP80920.1 - 0.11 12.4 0.2 0.35 10.8 0.2 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 PRP80920.1 - 0.22 11.5 1.1 0.97 9.4 1.1 2.1 1 0 0 1 1 1 0 F-box domain WD40 PF00400.32 PRP80921.1 - 3.3e-29 100.5 12.6 5e-05 24.0 1.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP80921.1 - 9.5e-09 35.5 0.0 0.42 10.9 0.0 4.6 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP80921.1 - 0.00032 20.6 0.1 0.91 9.4 0.1 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 PRP80921.1 - 0.017 13.7 5.8 6.6 5.2 0.0 4.4 2 2 2 5 5 5 0 Cytochrome D1 heme domain PQQ PF01011.21 PRP80921.1 - 0.044 13.7 2.1 0.16 11.9 0.1 2.8 4 0 0 4 4 4 0 PQQ enzyme repeat RTC PF01137.21 PRP80923.1 - 5.1e-20 71.6 0.2 5.8e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Abhydrolase_3 PF07859.13 PRP80924.1 - 2.3e-26 93.0 0.0 2.8e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PRP80924.1 - 0.0036 16.2 0.0 0.0039 16.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase GYD PF08734.11 PRP80924.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 GYD domain Ank_2 PF12796.7 PRP80928.1 - 7.8e-42 141.8 0.2 1.8e-19 70.1 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PRP80928.1 - 6.9e-26 89.5 1.7 2.2e-07 31.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 PRP80928.1 - 1.6e-21 74.1 0.5 5e-05 23.4 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 PRP80928.1 - 1.3e-18 67.1 0.0 1.8e-09 37.9 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP80928.1 - 4.3e-17 61.9 0.6 2.3e-05 24.6 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Bac_rhodopsin PF01036.18 PRP80929.1 - 7.5e-24 84.5 16.9 9.5e-24 84.2 16.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1686 PF07937.11 PRP80929.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1686) Fe-ADH PF00465.19 PRP80930.1 - 2.6e-97 325.9 0.0 3.5e-97 325.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase MFS_1 PF07690.16 PRP80930.1 - 2.6e-30 105.6 50.1 9.6e-22 77.4 22.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fe-ADH_2 PF13685.6 PRP80930.1 - 8.9e-12 45.2 0.1 2.5e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Sugar_tr PF00083.24 PRP80930.1 - 3e-07 29.6 14.0 2.2e-05 23.5 3.0 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter C_GCAxxG_C_C PF09719.10 PRP80930.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Arf PF00025.21 PRP80932.1 - 6.6e-74 247.1 0.2 7.3e-74 247.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PRP80932.1 - 1.7e-15 57.3 0.0 2.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP80932.1 - 6.9e-13 48.5 0.0 8.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 PRP80932.1 - 2.4e-12 46.7 1.7 1.9e-08 33.9 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PRP80932.1 - 2.1e-11 43.6 0.0 2.5e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PRP80932.1 - 7.5e-10 38.6 0.0 9.7e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP80932.1 - 7.3e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 PRP80932.1 - 0.013 14.8 0.5 0.02 14.2 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase MobB PF03205.14 PRP80932.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SpoOE-like PF09388.10 PRP80932.1 - 0.025 14.5 2.6 0.046 13.6 2.6 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Beta_helix PF13229.6 PRP80933.1 - 1e-14 54.7 197.2 5.2e-09 36.1 24.8 9.1 2 2 6 8 8 8 6 Right handed beta helix region Ras PF00071.22 PRP80934.1 - 4.4e-16 58.9 0.0 7.2e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP80934.1 - 5.7e-05 23.3 0.0 0.0004 20.6 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pkinase_Tyr PF07714.17 PRP80935.1 - 5.3e-79 265.1 0.0 7.8e-79 264.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80935.1 - 1.2e-50 172.4 0.0 1.8e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Chlam_PMP PF02415.17 PRP80935.1 - 8.1e-10 38.6 55.0 0.036 14.5 0.2 17.0 20 0 0 20 20 20 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kinase-like PF14531.6 PRP80935.1 - 0.00033 20.1 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP80935.1 - 0.05 13.0 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM52 PF14979.6 PRP80935.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane 52 Haspin_kinase PF12330.8 PRP80935.1 - 0.12 11.2 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain DUF5123 PF17161.4 PRP80935.1 - 2.6 9.2 24.9 1.4 10.1 0.2 7.6 5 3 3 8 8 8 0 Domain of unknown function (DUF5123) Myotub-related PF06602.14 PRP80936.1 - 1.6e-122 408.8 0.0 2.5e-122 408.2 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 PRP80936.1 - 0.0013 18.3 0.1 0.0024 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CENP-F_leu_zip PF10473.9 PRP80936.1 - 0.0029 17.6 1.4 0.0061 16.6 1.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DSPc PF00782.20 PRP80936.1 - 0.0089 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF3287 PF11690.8 PRP80936.1 - 0.019 14.7 0.1 0.061 13.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Y_phosphatase3 PF13350.6 PRP80936.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.20 PRP80936.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Senescence_reg PF04520.13 PRP80936.1 - 0.12 13.2 3.7 0.091 13.6 0.5 2.4 3 0 0 3 3 3 0 Senescence regulator 3-PAP PF12578.8 PRP80936.1 - 0.14 11.9 0.7 0.61 9.8 0.3 2.2 2 1 0 2 2 2 0 Myotubularin-associated protein DUF4527 PF15030.6 PRP80936.1 - 7.4 5.9 5.5 6.4 6.1 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) Zn_clus PF00172.18 PRP80937.1 - 2.1e-05 24.5 12.5 4.6e-05 23.4 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 PRP80937.1 - 0.00034 20.6 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold CtsR_C PF17727.1 PRP80937.1 - 0.018 15.2 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain TP2 PF01254.18 PRP80937.1 - 1.2 9.8 8.6 1.2 9.8 7.3 1.5 2 0 0 2 2 2 0 Nuclear transition protein 2 LRR_8 PF13855.6 PRP80938.1 - 9.9e-40 134.1 61.2 8e-12 44.8 1.3 5.8 2 1 6 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 PRP80938.1 - 1.6e-23 82.3 33.1 3e-05 24.3 6.7 7.0 3 3 3 7 7 7 5 Leucine Rich repeats (2 copies) Filamin PF00630.19 PRP80938.1 - 1.3e-13 51.7 0.1 2.2e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat LRR_9 PF14580.6 PRP80938.1 - 3.2e-07 30.0 17.3 0.029 13.9 4.1 4.2 1 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 PRP80938.1 - 1.4e-05 25.0 28.7 2.4 9.0 0.0 9.5 10 1 1 11 11 11 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP80938.1 - 0.00068 19.5 30.2 1.9 8.7 0.3 9.3 10 0 0 10 10 10 3 Leucine Rich repeat YtkA PF13115.6 PRP80938.1 - 0.039 14.6 0.1 0.07 13.7 0.1 1.4 1 0 0 1 1 1 0 YtkA-like Big_3 PF07523.12 PRP80938.1 - 0.2 12.0 0.1 0.67 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) RMI1_N PF08585.12 PRP80939.1 - 0.027 14.3 0.3 0.043 13.6 0.3 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein HEAT PF02985.22 PRP80940.1 - 1.8e-37 124.1 4.1 0.0076 16.4 0.0 12.1 12 0 0 12 12 12 9 HEAT repeat HEAT_2 PF13646.6 PRP80940.1 - 1.8e-25 89.1 0.0 0.0021 18.4 0.0 6.4 4 2 2 6 6 6 6 HEAT repeats Cnd1 PF12717.7 PRP80940.1 - 1.4e-07 31.7 4.6 0.28 11.2 0.0 4.8 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PRP80940.1 - 1.3e-06 27.3 6.0 0.00014 20.6 2.1 3.0 2 2 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 PRP80940.1 - 1.7e-06 28.6 1.1 0.77 10.4 0.0 4.7 3 1 2 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 PRP80940.1 - 0.00026 20.6 4.5 0.002 17.7 0.6 3.6 3 2 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 PRP80940.1 - 0.0084 16.6 0.2 87 3.8 0.0 5.4 5 0 0 5 5 5 0 HEAT-like repeat Herpes_BBRF1 PF04793.12 PRP80940.1 - 0.081 12.0 1.7 2.4 7.1 0.2 3.0 3 0 0 3 3 3 0 BRRF1-like protein X8 PF07983.13 PRP80941.1 - 2.2e-22 79.5 17.4 4.3e-13 49.7 5.1 2.6 2 0 0 2 2 2 2 X8 domain Glyco_hydro_17 PF00332.18 PRP80941.1 - 3.5e-05 23.5 2.4 0.0001 22.0 0.3 2.5 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 DUF2989 PF11207.8 PRP80941.1 - 0.015 15.0 0.2 4.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) TACI-CRD2 PF09305.10 PRP80941.1 - 0.033 14.2 0.2 0.33 11.0 0.1 2.4 2 0 0 2 2 2 0 TACI, cysteine-rich domain Ribosomal_L31 PF01197.18 PRP80941.1 - 0.13 12.5 1.5 18 5.7 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein L31 Folate_rec PF03024.14 PRP80941.1 - 0.46 10.3 12.1 1.5 8.7 3.7 2.5 2 0 0 2 2 2 0 Folate receptor family Glyco_transf_22 PF03901.17 PRP80942.1 - 2.4e-50 172.0 28.0 3.1e-50 171.6 28.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Mrr_cat PF04471.12 PRP80943.1 - 3.1e-08 33.6 0.0 1.3e-07 31.6 0.0 2.0 1 1 1 2 2 2 1 Restriction endonuclease Ank_5 PF13857.6 PRP80944.1 - 0.00024 21.3 0.1 0.096 13.0 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP80944.1 - 0.00088 19.8 0.0 0.0031 18.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80944.1 - 0.0026 18.3 0.1 14 6.4 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP80944.1 - 0.0042 17.5 0.1 0.81 10.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 PRP80944.1 - 0.037 14.6 0.1 0.88 10.3 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Thioredox_DsbH PF03190.15 PRP80945.1 - 7.2e-76 253.7 0.1 1.2e-75 252.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 PRP80945.1 - 3.4e-10 40.0 0.1 1.1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like C5-epim_C PF06662.13 PRP80945.1 - 0.00063 19.3 0.1 2.9 7.3 0.0 3.2 2 1 1 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 PRP80945.1 - 0.0073 14.9 0.0 0.2 10.1 0.0 2.1 2 0 0 2 2 2 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 PRP80945.1 - 0.0083 15.2 0.0 1.3 8.1 0.0 2.5 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 HTH_28 PF13518.6 PRP80945.1 - 0.078 13.1 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sec34 PF04136.15 PRP80946.1 - 0.0037 17.1 1.5 0.006 16.5 1.5 1.4 1 0 0 1 1 1 1 Sec34-like family FAP206 PF12018.8 PRP80946.1 - 0.013 15.0 1.5 0.018 14.6 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF1825 PF08855.10 PRP80946.1 - 0.07 13.1 1.9 1.1 9.2 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) BLOC1_2 PF10046.9 PRP80946.1 - 0.093 13.0 4.3 0.071 13.4 1.9 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RSN1_7TM PF02714.15 PRP80946.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate Mce4_CUP1 PF11887.8 PRP80946.1 - 0.17 11.3 1.0 0.19 11.1 1.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative PH PF00169.29 PRP80948.1 - 1.1e-11 45.1 0.1 3.8e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP80948.1 - 5.1e-06 26.8 1.4 0.0095 16.3 0.2 2.8 1 1 1 2 2 2 2 Pleckstrin homology domain Focal_AT PF03623.13 PRP80948.1 - 0.021 14.8 0.1 0.41 10.6 0.0 2.9 3 1 1 4 4 4 0 Focal adhesion targeting region PH_8 PF15409.6 PRP80948.1 - 0.23 11.8 1.0 0.67 10.3 1.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Con-6 PF10346.9 PRP80949.1 - 1.8e-37 127.0 18.0 8.1e-13 48.2 2.2 3.6 3 0 0 3 3 3 3 Conidiation protein 6 Metallophos PF00149.28 PRP80949.1 - 6.7e-21 75.7 1.4 2.6e-20 73.8 1.1 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA PF00004.29 PRP80949.1 - 4.8e-16 59.4 0.0 1.3e-15 58.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pur_ac_phosph_N PF16656.5 PRP80949.1 - 1.6e-08 35.0 0.5 1.6e-08 35.0 0.5 2.3 2 0 0 2 2 1 1 Purple acid Phosphatase, N-terminal domain KGG PF10685.9 PRP80949.1 - 3.4e-06 27.1 0.1 3.4e-06 27.1 0.1 2.7 3 0 0 3 3 2 1 Stress-induced bacterial acidophilic repeat motif AAA_22 PF13401.6 PRP80949.1 - 0.00029 21.1 0.2 0.0032 17.7 0.0 2.8 2 1 1 3 3 2 1 AAA domain Arm-DNA-bind_3 PF13356.6 PRP80949.1 - 0.00037 20.8 0.9 10 6.6 0.0 3.7 3 0 0 3 3 3 0 Arm DNA-binding domain AAA_16 PF13191.6 PRP80949.1 - 0.0005 20.5 0.3 0.0034 17.8 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PRP80949.1 - 0.0016 18.5 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PRP80949.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 PRP80949.1 - 0.018 14.8 0.0 0.018 14.8 0.0 3.5 2 1 0 2 2 1 0 AAA domain Phage_lambda_P PF06992.11 PRP80949.1 - 0.031 14.0 6.7 5.7 6.6 0.1 3.8 3 0 0 3 3 3 0 Replication protein P AAA_30 PF13604.6 PRP80949.1 - 0.053 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PRP80949.1 - 0.053 13.9 0.0 3.8 7.9 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.6 PRP80949.1 - 0.098 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Metallophos_C PF14008.6 PRP80949.1 - 0.12 13.3 0.0 0.43 11.5 0.0 2.1 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C Pga1 PF10333.9 PRP80949.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator PhdYeFM_antitox PF02604.19 PRP80949.1 - 9.6 6.1 6.8 17 5.3 0.2 3.4 4 0 0 4 4 3 0 Antitoxin Phd_YefM, type II toxin-antitoxin system PH PF00169.29 PRP80950.1 - 2.9e-16 59.9 1.4 8.2e-12 45.6 0.0 2.7 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 PRP80950.1 - 1.2e-06 28.9 6.4 0.0031 17.9 0.9 4.0 2 2 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PRP80950.1 - 7.6e-06 26.0 0.9 0.00034 20.7 0.0 2.6 2 1 0 2 2 2 1 PH domain PH_15 PF17339.2 PRP80950.1 - 3.6e-05 23.6 0.1 0.38 10.7 0.0 2.4 2 0 0 2 2 2 2 PH domain MSP1_C PF07462.11 PRP80950.1 - 0.0097 14.7 0.4 0.013 14.3 0.4 1.2 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus GEMIN8 PF15348.6 PRP80950.1 - 0.033 14.5 3.0 0.056 13.7 3.0 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CENP-B_dimeris PF09026.10 PRP80950.1 - 0.24 11.8 8.0 0.56 10.6 8.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PH_4 PF15404.6 PRP80950.1 - 0.39 10.5 2.0 7.9 6.2 0.0 3.4 4 0 0 4 4 4 0 Pleckstrin homology domain Cwf_Cwc_15 PF04889.12 PRP80950.1 - 0.65 9.7 8.1 1.2 8.8 8.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 PRP80950.1 - 0.83 9.3 5.0 1.9 8.2 5.0 1.6 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 PRP80950.1 - 0.94 8.7 7.7 1.5 8.0 7.7 1.3 1 0 0 1 1 1 0 NOA36 protein Bromodomain PF00439.25 PRP80952.1 - 1.2e-18 66.9 1.1 4.5e-18 65.1 1.1 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 PRP80952.1 - 0.00061 19.7 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated Mannosyl_trans2 PF04188.13 PRP80954.1 - 3.3e-73 247.5 33.4 5.4e-73 246.8 33.4 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) TIMELESS PF04821.14 PRP80955.1 - 5.8e-50 170.1 6.4 5.8e-50 170.1 6.4 3.6 4 1 0 4 4 4 1 Timeless protein TIMELESS_C PF05029.13 PRP80955.1 - 5.1e-07 29.2 0.2 5.1e-07 29.2 0.2 4.3 2 2 1 3 3 3 2 Timeless protein C terminal region Glyco_hydro_18 PF00704.28 PRP80957.1 - 8.1e-64 216.3 1.5 1.2e-63 215.8 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MBOAT_2 PF13813.6 PRP80957.1 - 4.7e-13 49.2 0.0 4.5e-12 46.1 0.0 2.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF2070 PF09843.9 PRP80957.1 - 2.4 6.4 12.6 5.3 5.2 12.1 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) SprA-related PF12118.8 PRP80957.1 - 2.6 7.1 7.5 4.2 6.4 7.5 1.3 1 0 0 1 1 1 0 SprA-related family DUF5542 PF17696.1 PRP80958.1 - 0.021 14.9 2.2 0.048 13.8 1.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5542) HECT PF00632.25 PRP80961.1 - 1.5e-32 113.3 0.2 2.5e-32 112.6 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SNARE_assoc PF09335.11 PRP80964.1 - 9.1e-20 71.3 3.6 9.1e-20 71.3 3.6 2.2 1 1 1 2 2 2 1 SNARE associated Golgi protein Phage_holin_2_1 PF04971.12 PRP80964.1 - 0.034 14.2 0.5 0.034 14.2 0.5 3.2 3 2 0 3 3 3 0 Bacteriophage P21 holin S Syndecan PF01034.20 PRP80964.1 - 0.038 13.9 0.9 0.11 12.4 0.3 2.1 2 0 0 2 2 2 0 Syndecan domain DUF5385 PF17359.2 PRP80964.1 - 0.17 11.4 0.4 0.27 10.8 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Stevor PF17410.2 PRP80964.1 - 0.17 11.4 0.8 0.3 10.6 0.8 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame RIFIN PF02009.16 PRP80964.1 - 0.83 9.5 2.3 0.58 10.0 0.3 1.6 2 0 0 2 2 2 0 Rifin Sugar_tr PF00083.24 PRP80965.1 - 2.6e-115 385.9 19.4 3.2e-115 385.6 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP80965.1 - 2.1e-30 105.9 32.5 1.7e-21 76.5 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase_Tyr PF07714.17 PRP80967.1 - 1e-28 100.3 0.1 1.6e-28 99.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP80967.1 - 1.8e-27 94.9 41.6 3.9e-06 26.5 5.1 7.7 5 2 2 7 7 7 7 Leucine rich repeat Pkinase PF00069.25 PRP80967.1 - 2e-17 63.4 0.1 3.4e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP80967.1 - 1.6e-09 37.8 58.3 0.0019 18.6 2.7 9.6 5 2 7 13 13 13 9 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP80967.1 - 3.4e-09 37.1 0.8 1.3e-08 35.2 0.8 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_10 PF18805.1 PRP80967.1 - 0.005 16.5 1.8 12 5.6 0.1 3.5 3 0 0 3 3 3 1 Leucine-rich repeat Lipoxygenase PF00305.19 PRP80969.1 - 2.2e-39 135.5 4.1 3.9e-27 95.0 2.5 3.0 3 0 0 3 3 3 3 Lipoxygenase AMPK1_CBM PF16561.5 PRP80969.1 - 7.6e-08 32.5 0.1 1.9e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pkinase PF00069.25 PRP80970.1 - 1.3e-30 106.7 0.4 2.1e-30 106.0 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP80970.1 - 9.4e-29 100.5 0.3 2.9e-28 98.9 0.3 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP80970.1 - 1.3e-10 41.6 3.1 1.3e-10 41.6 3.1 2.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif B_lectin PF01453.24 PRP80970.1 - 0.013 16.0 0.3 0.043 14.4 0.3 1.9 1 0 0 1 1 1 0 D-mannose binding lectin Tad_C PF09977.9 PRP80970.1 - 0.13 13.5 0.1 0.45 11.8 0.1 1.9 1 0 0 1 1 1 0 Putative Tad-like Flp pilus-assembly PEMT PF04191.13 PRP80971.1 - 3.5e-25 88.5 3.1 3.5e-25 88.5 3.1 2.0 2 1 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 PRP80971.1 - 0.012 16.0 2.3 0.012 16.0 2.3 2.4 2 1 1 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family VirB3 PF05101.13 PRP80971.1 - 1.8 8.8 7.4 3.2 8.1 0.0 3.1 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Homeodomain PF00046.29 PRP80972.1 - 5.9e-05 22.8 3.1 0.00076 19.3 0.1 2.4 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 PRP80972.1 - 0.12 12.3 0.2 30 4.6 0.0 3.1 2 1 0 2 2 2 0 Homeobox KN domain HTH_32 PF13565.6 PRP80972.1 - 0.55 10.9 4.4 0.43 11.2 1.6 2.2 2 1 0 2 2 2 0 Homeodomain-like domain MAPEG PF01124.18 PRP80973.1 - 7.5e-14 51.7 0.1 7.5e-14 51.7 0.1 3.0 4 0 0 4 4 4 1 MAPEG family Choline_transpo PF04515.12 PRP80973.1 - 3.4e-13 49.5 37.3 3.4e-13 49.5 37.3 3.2 4 0 0 4 4 4 1 Plasma-membrane choline transporter Dpy-30 PF05186.13 PRP80974.1 - 5.5e-06 26.0 1.0 0.029 14.1 0.2 2.4 2 0 0 2 2 2 2 Dpy-30 motif AMP-binding PF00501.28 PRP80975.1 - 1.3e-75 254.7 0.0 1.7e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 PRP80975.1 - 5.8e-65 219.0 0.0 1.1e-64 218.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AlaDh_PNT_N PF05222.15 PRP80975.1 - 6.6e-26 91.2 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AMP-binding_C PF13193.6 PRP80975.1 - 3.4e-12 47.2 0.1 1.5e-11 45.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 PRP80975.1 - 1.6e-11 44.4 0.0 4.6e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 PRP80975.1 - 8.3e-10 38.5 0.0 6.7e-09 35.6 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 PRP80975.1 - 7.9e-06 24.8 0.0 0.00054 18.8 0.0 2.3 1 1 0 1 1 1 1 Condensation domain RmlD_sub_bind PF04321.17 PRP80975.1 - 9.8e-06 24.9 0.0 0.00053 19.2 0.0 2.6 2 1 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 PRP80975.1 - 2.5e-05 23.5 0.0 5.5e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 PRP80975.1 - 0.00092 18.6 0.0 0.035 13.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Polysacc_synt_2 PF02719.15 PRP80975.1 - 0.032 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase_Tyr PF07714.17 PRP80976.1 - 8.4e-29 100.6 0.4 1.6e-27 96.4 0.2 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP80976.1 - 2.6e-27 95.8 0.3 4.7e-27 95.0 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP80976.1 - 1.2e-10 41.7 2.6 1.2e-10 41.7 2.6 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif B_lectin PF01453.24 PRP80976.1 - 0.00022 21.7 0.5 0.0008 19.9 0.5 1.9 1 0 0 1 1 1 1 D-mannose binding lectin YwiC PF14256.6 PRP80976.1 - 0.42 10.9 1.8 2.4 8.5 0.4 2.3 2 0 0 2 2 2 0 YwiC-like protein HATPase_c PF02518.26 PRP80977.1 - 1.9e-28 99.2 0.0 3.6e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP80977.1 - 1.2e-22 80.2 0.7 3.7e-21 75.4 0.1 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 PRP80977.1 - 1.1e-12 47.8 0.0 4.4e-12 45.8 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain RAP PF08373.10 PRP80977.1 - 0.72 10.0 2.3 0.95 9.6 0.8 1.9 2 0 0 2 2 2 0 RAP domain Ank_2 PF12796.7 PRP80978.1 - 8.9e-45 151.2 0.0 5.9e-12 46.0 0.0 5.1 2 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP80978.1 - 6e-34 116.0 7.1 2.9e-05 24.5 0.0 8.3 2 1 8 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP80978.1 - 7.1e-23 80.4 0.9 0.12 12.7 0.5 10.0 3 3 8 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP80978.1 - 7.5e-20 68.9 1.0 0.28 11.9 0.0 11.0 12 1 1 13 13 13 5 Ankyrin repeat Ank PF00023.30 PRP80978.1 - 2.5e-19 68.8 8.8 0.12 12.8 0.0 11.5 8 4 3 11 11 11 7 Ankyrin repeat SoxZ PF08770.11 PRP80978.1 - 0.11 12.3 0.0 3.4 7.5 0.0 3.2 2 1 2 4 4 4 0 Sulphur oxidation protein SoxZ VWA_3_C PF18571.1 PRP80978.1 - 0.13 12.2 6.7 61 3.6 0.0 6.8 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain HATPase_c PF02518.26 PRP80979.1 - 2.3e-28 98.9 0.0 4.5e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP80979.1 - 2.6e-22 79.1 0.6 7.3e-21 74.4 0.1 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 PRP80979.1 - 5.8e-13 48.7 0.6 4.1e-12 46.0 0.0 2.7 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CooT PF10133.9 PRP80979.1 - 0.0004 20.6 0.8 1.9 8.9 0.1 3.0 2 0 0 2 2 2 2 CO dehydrogenase accessory protein CooT HATPase_c_5 PF14501.6 PRP80979.1 - 0.089 12.7 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 GHKL domain YokU PF14122.6 PRP80979.1 - 0.27 11.2 5.4 9.8 6.2 0.2 3.3 3 0 0 3 3 3 0 YokU-like protein, putative antitoxin DUF848 PF05852.11 PRP80979.1 - 0.37 10.9 1.9 20 5.3 0.1 2.9 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) HALZ PF02183.18 PRP80979.1 - 3.4 8.0 5.1 91 3.4 0.0 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper DAO PF01266.24 PRP80980.1 - 1.3e-52 179.5 0.3 1.9e-52 179.0 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 PRP80980.1 - 2.3e-37 127.7 0.1 4e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 PRP80980.1 - 1.2e-10 41.0 2.6 7.4e-06 25.3 1.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 PRP80980.1 - 2.2e-10 40.5 1.3 2.4e-07 30.4 0.4 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PRP80980.1 - 4.5e-07 29.4 0.4 4.9e-06 26.0 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 PRP80980.1 - 5.5e-06 25.7 0.6 0.00015 21.0 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 PRP80980.1 - 7.3e-05 22.1 1.4 0.00044 19.6 1.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP80980.1 - 0.0016 17.7 0.0 0.0072 15.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP80980.1 - 0.003 16.3 0.3 0.005 15.6 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 PRP80980.1 - 0.0062 15.8 0.5 0.013 14.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 PRP80980.1 - 0.044 14.0 1.4 0.15 12.3 0.8 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PRP80980.1 - 0.11 13.0 0.6 0.44 11.1 0.1 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CBS PF00571.28 PRP80981.1 - 5.7e-37 126.0 7.9 4.8e-09 36.5 0.5 4.5 4 1 0 4 4 4 4 CBS domain DisA_N PF02457.16 PRP80981.1 - 0.011 15.3 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding TmoB PF06234.12 PRP80981.1 - 0.27 11.4 2.6 0.42 10.7 0.2 2.6 3 0 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) Homeodomain PF00046.29 PRP80982.1 - 1.3e-14 53.8 3.1 2.6e-14 52.8 3.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP80982.1 - 0.00035 20.4 0.9 0.00075 19.4 0.9 1.5 1 0 0 1 1 1 1 Homeobox KN domain DLH PF01738.18 PRP80983.1 - 3.5e-26 92.1 0.0 5.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 PRP80983.1 - 0.0068 16.0 0.1 0.009 15.6 0.1 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 PRP80983.1 - 0.043 13.4 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase PF07224.11 PRP80983.1 - 0.2 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase PTH2 PF01981.16 PRP80984.1 - 3.4e-35 120.9 0.0 4.9e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3824 PF12868.7 PRP80984.1 - 0.0093 16.6 0.5 0.013 16.2 0.5 1.2 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) FAM176 PF14851.6 PRP80984.1 - 0.019 14.6 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 PRP80984.1 - 0.11 10.7 7.1 0.14 10.3 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PRP80984.1 - 0.34 9.0 11.2 0.42 8.7 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi AIM3 PF17096.5 PRP80984.1 - 0.79 10.7 4.2 1.7 9.7 4.2 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Pox_Ag35 PF03286.14 PRP80984.1 - 0.95 9.2 6.5 1.7 8.4 6.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 PRP80984.1 - 1.1 9.4 14.8 1.6 8.9 14.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Homeodomain PF00046.29 PRP80987.1 - 3.5e-11 42.8 0.0 1.2e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP80987.1 - 5.6e-10 39.0 2.7 2e-09 37.2 0.2 2.9 3 0 0 3 3 3 1 Homeobox KN domain Homez PF11569.8 PRP80987.1 - 0.031 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez vATP-synt_AC39 PF01992.16 PRP80988.1 - 8e-119 397.1 2.3 8.9e-119 396.9 2.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit COMMD1_N PF17221.3 PRP80990.1 - 1.8e-13 50.7 0.3 3.5e-13 49.7 0.1 1.6 2 1 0 2 2 2 1 COMMD1 N-terminal domain COMM_domain PF07258.14 PRP80990.1 - 2.9e-08 33.7 0.4 5.4e-08 32.8 0.4 1.5 1 0 0 1 1 1 1 COMM domain HMG_box PF00505.19 PRP80992.1 - 3.9e-09 36.8 0.6 1.1e-08 35.4 0.6 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PRP80992.1 - 1.3e-06 28.9 0.2 3.1e-06 27.7 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 PRP80992.1 - 0.02 15.0 0.0 0.094 12.8 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) WH2 PF02205.20 PRP80992.1 - 0.17 11.7 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 WH2 motif Baculo_helicase PF04735.12 PRP80992.1 - 0.19 9.2 0.0 0.27 8.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase Bac_rhodopsin PF01036.18 PRP80993.1 - 7.3e-15 55.2 14.3 9.8e-15 54.7 14.3 1.2 1 1 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2568 PF10823.8 PRP80993.1 - 0.006 16.8 2.9 0.006 16.8 2.9 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2568) MFS_1 PF07690.16 PRP80994.1 - 1.4e-39 136.0 43.4 1.4e-39 136.0 43.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PRP80994.1 - 5.7e-08 31.6 4.8 5.7e-08 31.6 4.8 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 PRP80994.1 - 2.6e-05 23.3 22.9 4.8e-05 22.4 22.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1129 PF06570.11 PRP80994.1 - 0.57 9.6 2.8 1.6 8.2 2.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Romo1 PF10247.9 PRP80994.1 - 3.4 8.1 7.1 4.1 7.8 0.1 3.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 RGS PF00615.19 PRP80995.1 - 0.13 12.5 0.3 8.2 6.7 0.3 2.4 1 1 0 1 1 1 0 Regulator of G protein signaling domain F-box PF00646.33 PRP80996.1 - 4.5e-05 23.2 0.1 0.00012 21.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP80996.1 - 0.0025 17.7 0.5 0.0072 16.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 PRP80996.1 - 0.0036 17.2 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 F-box Ank_4 PF13637.6 PRP80996.1 - 0.056 14.0 0.3 7.5 7.3 0.0 3.8 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP80996.1 - 0.094 13.3 0.1 16 6.1 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP80996.1 - 0.18 12.2 3.4 16 5.9 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeats (many copies) DUF249 PF03158.13 PRP80996.1 - 0.28 10.9 1.2 10 5.8 0.0 2.8 2 1 0 2 2 2 0 Multigene family 530 protein DUF2095 PF09868.9 PRP80996.1 - 1.4 8.9 6.3 14 5.6 0.1 4.0 3 2 2 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2095) Peroxidase_2 PF01328.17 PRP80999.1 - 2.9e-13 50.8 0.0 4e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 F-box PF00646.33 PRP81000.1 - 4.5e-05 23.2 2.3 5.4e-05 23.0 0.5 2.1 2 0 0 2 2 2 1 F-box domain Ank_4 PF13637.6 PRP81000.1 - 0.0035 17.9 0.2 54 4.5 0.0 5.3 3 2 2 5 5 5 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP81000.1 - 0.033 14.1 0.6 0.084 12.8 0.6 1.7 1 0 0 1 1 1 0 F-box-like CDP-OH_P_transf PF01066.21 PRP81003.1 - 1.9e-12 47.8 1.2 1.9e-12 47.8 1.2 3.4 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Spore_YhaL PF14147.6 PRP81003.1 - 0.45 10.2 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Sporulation protein YhaL p450 PF00067.22 PRP81004.1 - 2.7e-78 263.8 0.1 1.6e-77 261.3 0.0 2.1 3 0 0 3 3 3 1 Cytochrome P450 BTB_2 PF02214.22 PRP81004.1 - 2.5e-07 31.0 0.1 5.8e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 BTB/POZ domain Aconitase PF00330.20 PRP81006.1 - 6.7e-179 595.7 0.0 9.1e-179 595.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 PRP81006.1 - 7.6e-37 126.6 0.0 1.3e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 PRP81006.1 - 0.0013 18.4 0.1 0.0031 17.2 0.0 1.6 2 0 0 2 2 2 1 Aconitate hydratase 2 N-terminus DUF668 PF05003.12 PRP81006.1 - 0.091 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Ank_4 PF13637.6 PRP81007.1 - 0.00057 20.4 0.7 0.43 11.2 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeats (many copies) NRho PF16733.5 PRP81007.1 - 0.022 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Rhomboid N-terminal domain Ank_3 PF13606.6 PRP81007.1 - 0.094 13.3 0.6 4.7e+02 2.0 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 PRP81007.1 - 0.11 13.2 0.2 7.3 7.3 0.0 3.4 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) ATE_C PF04377.15 PRP81008.1 - 1.2e-45 155.4 4.3 4.1e-45 153.7 4.3 1.9 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 PRP81008.1 - 2.6e-22 79.0 4.5 7e-22 77.6 4.5 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF3652 PF12372.8 PRP81008.1 - 0.014 15.3 0.2 0.026 14.4 0.2 1.4 1 0 0 1 1 1 0 Huntingtin protein region DUF3726 PF12525.8 PRP81008.1 - 0.023 14.8 0.0 0.095 12.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) Drf_GBD PF06371.13 PRP81008.1 - 1.1 8.7 4.7 0.53 9.8 1.9 1.8 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain TFIIE-A_C PF11521.8 PRP81008.1 - 6.6 7.1 8.6 3.6 8.0 0.0 2.7 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha HECT PF00632.25 PRP81010.1 - 1.1e-92 310.9 0.1 2.1e-92 309.9 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) F-box PF00646.33 PRP81010.1 - 0.014 15.3 0.0 0.043 13.7 0.0 1.9 1 0 0 1 1 1 0 F-box domain Ribosomal_S28e PF01200.18 PRP81011.1 - 1.8e-32 111.1 0.9 1.9e-32 111.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Acetyltransf_10 PF13673.7 PRP81012.1 - 9.8e-13 48.2 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP81012.1 - 3.7e-09 36.8 0.0 4.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP81012.1 - 4.7e-09 36.5 0.0 6.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP81012.1 - 2.2e-07 30.7 0.0 3.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.6 PRP81012.1 - 4e-07 30.7 0.0 1.2e-06 29.1 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Ank_4 PF13637.6 PRP81013.1 - 6.8e-30 103.1 0.8 1.9e-09 37.9 0.2 4.7 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81013.1 - 4.1e-28 97.8 4.3 6.2e-14 52.3 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PRP81013.1 - 7e-26 89.5 3.8 6.9e-07 29.4 0.4 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PRP81013.1 - 1.6e-25 88.9 1.0 2e-07 31.2 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81013.1 - 3.2e-23 79.3 0.8 5.8e-05 23.2 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Methyltransf_11 PF08241.12 PRP81013.1 - 1.4e-14 54.5 0.0 3.1e-14 53.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP81013.1 - 1.4e-10 41.3 0.0 2.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP81013.1 - 2.4e-10 41.0 0.0 6.3e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP81013.1 - 4.4e-09 36.3 0.0 1.9e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP81013.1 - 1.1e-07 32.4 0.0 3.6e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP81013.1 - 0.0035 16.7 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 PRP81013.1 - 0.029 13.9 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain zf-CCCH PF00642.24 PRP81014.1 - 1.1e-20 73.1 16.5 9.6e-11 41.3 5.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PRP81014.1 - 3.7e-17 61.7 10.7 1.5e-08 34.3 1.1 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PRP81014.1 - 8.9e-13 47.8 17.3 2.7e-06 27.3 3.4 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 PRP81014.1 - 0.00013 22.3 9.2 0.05 14.1 1.5 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PRP81014.1 - 0.00025 21.7 9.5 0.019 15.7 0.9 2.6 1 1 1 2 2 2 2 Torus domain oligo_HPY PF08352.12 PRP81014.1 - 0.14 12.7 2.8 14 6.2 0.1 2.6 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region CutA1 PF03091.15 PRP81015.1 - 6.4e-17 61.2 0.0 9.8e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein tRNA-synt_1 PF00133.22 PRP81016.1 - 1.2e-162 542.3 0.6 5.4e-162 540.2 0.6 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PRP81016.1 - 7.3e-27 94.1 0.0 1.5e-17 63.4 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PRP81016.1 - 4e-23 82.1 0.1 8.5e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PRP81016.1 - 0.023 14.1 0.0 0.97 8.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF3605 PF12239.8 PRP81017.1 - 9.2e-30 104.0 0.1 2e-29 102.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) GPS PF01825.21 PRP81018.1 - 4.7e-11 43.0 3.9 1.1e-10 41.8 3.9 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP81018.1 - 1.4e-09 37.7 0.1 1.1e-08 34.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81018.1 - 1.3e-08 34.5 0.1 8.2e-08 31.9 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP81019.1 - 1.1e-09 37.9 10.0 0.00044 20.0 0.4 4.6 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 PRP81019.1 - 9.3e-09 35.4 18.8 0.0033 17.8 0.8 5.4 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP81019.1 - 0.0002 21.1 0.5 1.6 9.0 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich repeat TIG PF01833.24 PRP81019.1 - 0.00026 21.0 6.6 0.0052 16.8 3.9 2.6 2 0 0 2 2 2 1 IPT/TIG domain LRR_1 PF00560.33 PRP81019.1 - 0.0097 16.3 5.5 79 4.4 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat CBS PF00571.28 PRP81020.1 - 8.8e-18 64.5 0.7 5.9e-06 26.6 0.0 4.3 4 0 0 4 4 4 4 CBS domain DSPc PF00782.20 PRP81021.1 - 3.1e-34 117.6 0.1 4.8e-34 117.0 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 PRP81021.1 - 2.6e-08 34.3 0.0 3.6e-06 27.5 0.0 3.0 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.27 PRP81021.1 - 0.0023 17.5 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 PRP81021.1 - 0.0097 15.5 0.1 0.018 14.6 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family GARS_C PF02843.16 PRP81021.1 - 0.091 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, C domain Y_phosphatase3 PF13350.6 PRP81021.1 - 0.14 12.1 0.1 1.9 8.4 0.0 2.2 1 1 1 2 2 2 0 Tyrosine phosphatase family RRM_1 PF00076.22 PRP81022.1 - 1.7e-22 79.0 0.2 2.9e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP81022.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PRP81022.1 - 0.00013 21.9 1.8 0.00021 21.2 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_occluded PF16842.5 PRP81022.1 - 0.00018 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_8 PF11835.8 PRP81022.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 RRM-like domain zf-CCHC_3 PF13917.6 PRP81022.1 - 0.017 15.1 0.6 0.03 14.3 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle RNA_bind PF08675.11 PRP81022.1 - 0.076 13.1 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 RNA binding domain ATP-synt_C PF00137.21 PRP81024.1 - 1.5e-25 89.3 23.4 8.1e-15 54.9 12.7 2.7 2 0 0 2 2 2 2 ATP synthase subunit C SLC3A2_N PF16028.5 PRP81024.1 - 0.17 11.5 2.7 0.69 9.5 1.4 2.3 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus UPF0731 PF14982.6 PRP81024.1 - 0.18 12.0 1.1 2.1 8.6 0.2 2.6 2 0 0 2 2 2 0 UPF0731 family FPL PF09758.9 PRP81025.1 - 3.7e-63 212.0 12.3 7.8e-63 210.9 12.3 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein SH2 PF00017.24 PRP81026.1 - 5.1e-16 58.5 0.0 7.2e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 SH2 domain E1_DerP2_DerF2 PF02221.15 PRP81027.1 - 3.5e-20 72.8 0.1 4.5e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 ML domain NPCBM_assoc PF10633.9 PRP81027.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SASA PF03629.18 PRP81029.1 - 5.8e-13 49.0 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase HEAT PF02985.22 PRP81029.1 - 0.0003 20.8 1.6 68 4.1 0.0 6.4 6 0 0 6 6 6 0 HEAT repeat Cnd1 PF12717.7 PRP81029.1 - 0.022 14.8 10.4 2.5 8.1 0.0 6.7 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Spo7_2_N PF15407.6 PRP81029.1 - 0.069 12.8 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 Sporulation protein family 7 PDGF PF00341.17 PRP81030.1 - 0.053 13.8 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 PDGF/VEGF domain Acetyltransf_1 PF00583.25 PRP81037.1 - 8.8e-14 51.7 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP81037.1 - 2.9e-11 43.4 0.1 5e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP81037.1 - 1e-09 38.7 0.2 1.9e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP81037.1 - 0.00012 22.2 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP81037.1 - 0.0013 19.5 0.0 0.0021 18.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP81037.1 - 0.0014 18.7 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP81037.1 - 0.0028 17.7 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 PRP81037.1 - 0.011 15.6 0.0 0.96 9.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP81037.1 - 0.024 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 PRP81037.1 - 0.046 13.4 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Patatin PF01734.22 PRP81038.1 - 9.7e-09 35.7 6.1 9.7e-09 35.7 6.1 2.5 2 1 0 2 2 2 1 Patatin-like phospholipase FAD_binding_1 PF00667.20 PRP81039.1 - 1.3e-19 70.6 0.0 1.9e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Oxidored-like PF09791.9 PRP81039.1 - 6.5e-12 44.9 6.4 3.5e-11 42.6 4.2 2.5 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal NAD_binding_1 PF00175.21 PRP81039.1 - 0.00092 19.8 0.7 0.0021 18.7 0.1 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PPR_2 PF13041.6 PRP81040.1 - 1.3e-23 82.9 1.1 5e-08 33.0 0.0 4.8 2 2 3 5 5 5 5 PPR repeat family PPR_3 PF13812.6 PRP81040.1 - 1e-17 63.9 0.4 2.1e-08 34.1 0.0 3.4 2 1 2 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 PRP81040.1 - 7.6e-15 54.0 2.9 0.0026 17.9 0.0 5.5 5 0 0 5 5 5 4 PPR repeat Ank_2 PF12796.7 PRP81040.1 - 8.1e-11 42.4 0.0 1.6e-05 25.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PPR_long PF17177.4 PRP81040.1 - 2.8e-07 30.1 0.0 5.6e-05 22.6 0.0 2.2 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP81040.1 - 2.4e-05 23.9 0.0 0.22 11.2 0.0 4.0 4 0 0 4 4 4 1 PPR repeat Ank_5 PF13857.6 PRP81040.1 - 0.00011 22.4 0.1 1.3 9.4 0.0 3.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP81040.1 - 0.00033 21.1 2.1 7.1 7.3 0.0 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) SHR-BD PF06650.12 PRP81040.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 SHR-binding domain of vacuolar-sorting associated protein 13 Ank_3 PF13606.6 PRP81040.1 - 0.18 12.5 0.0 31 5.6 0.0 3.4 3 0 0 3 3 2 0 Ankyrin repeat Hep_59 PF07052.11 PRP81040.1 - 0.63 10.8 6.4 0.35 11.7 0.7 2.5 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 WRNPLPNID PF15017.6 PRP81040.1 - 2 9.3 5.9 5.8 7.9 5.9 1.8 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Fis1_TPR_C PF14853.6 PRP81041.1 - 1.2e-20 73.3 1.3 1.4e-20 73.1 0.1 1.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 PRP81041.1 - 0.00014 21.7 0.4 0.00072 19.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP81041.1 - 0.0058 17.1 0.1 0.01 16.3 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP81041.1 - 0.027 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PRP81041.1 - 0.043 14.7 0.0 0.68 10.9 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP81041.1 - 0.11 13.2 0.0 0.95 10.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 PRP81041.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat LRR_9 PF14580.6 PRP81042.1 - 2.8e-12 46.5 0.3 4.6e-12 45.8 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PRP81042.1 - 1.9e-07 31.3 17.7 0.0019 18.5 8.9 3.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP81042.1 - 0.0035 17.1 6.3 0.0035 17.1 6.3 2.8 1 1 1 2 2 2 2 Leucine rich repeat CDC45 PF02724.14 PRP81042.1 - 1.2 7.4 16.7 1.4 7.1 16.7 1.2 1 0 0 1 1 1 0 CDC45-like protein LRR_6 PF13516.6 PRP81042.1 - 9.2 6.6 12.0 4.7 7.5 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat UVR PF02151.19 PRP81043.1 - 5.3e-07 29.2 17.0 6.2e-05 22.6 1.1 3.2 3 0 0 3 3 3 2 UvrB/uvrC motif TMF_DNA_bd PF12329.8 PRP81043.1 - 0.041 13.9 1.3 0.041 13.9 1.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Thiamine_BP PF01910.17 PRP81043.1 - 0.068 13.1 1.0 9 6.3 0.0 2.3 2 0 0 2 2 2 0 Thiamine-binding protein SBDS_C PF09377.10 PRP81043.1 - 0.12 12.4 2.4 0.21 11.6 2.2 1.4 1 1 0 1 1 1 0 SBDS protein C-terminal domain NPBW PF15180.6 PRP81043.1 - 0.23 11.3 0.8 15 5.5 0.1 2.2 1 1 1 2 2 2 0 Neuropeptides B and W WD40 PF00400.32 PRP81044.1 - 1.5e-28 98.4 10.2 0.0016 19.2 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat Ank_2 PF12796.7 PRP81044.1 - 8.5e-24 84.0 0.4 5e-11 43.0 0.5 3.9 2 1 2 4 4 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81044.1 - 1.6e-20 73.2 0.6 4.3e-10 39.9 0.4 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP81044.1 - 4.7e-18 64.8 0.1 1.7e-05 25.0 0.2 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PRP81044.1 - 8.8e-18 64.1 1.3 5.3e-07 29.8 0.1 4.0 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81044.1 - 1.6e-15 55.7 0.4 0.00093 19.5 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat ANAPC4_WD40 PF12894.7 PRP81044.1 - 1.7e-07 31.4 3.4 0.16 12.3 0.0 5.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP81044.1 - 6.9e-07 28.9 5.4 0.0014 18.0 2.1 2.4 1 1 1 2 2 2 2 WD40-like domain FYVE PF01363.21 PRP81044.1 - 0.0034 17.5 13.0 0.012 15.7 13.0 1.9 1 1 0 1 1 1 1 FYVE zinc finger BBS2_Mid PF14783.6 PRP81044.1 - 0.0068 16.4 0.6 0.67 10.0 0.0 3.7 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PH_6 PF15406.6 PRP81044.1 - 0.017 15.4 0.1 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain zf-RING_5 PF14634.6 PRP81044.1 - 0.19 11.7 11.8 0.38 10.8 11.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain MLD PF11647.8 PRP81044.1 - 0.52 10.6 3.9 1.2 9.5 1.0 3.0 2 0 0 2 2 2 0 Membrane Localization Domain zf-C3HC4_3 PF13920.6 PRP81044.1 - 3.4 7.6 11.4 6.6 6.7 11.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lebercilin PF15619.6 PRP81045.1 - 1.3 8.7 48.2 0.29 10.8 1.0 5.3 3 2 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.12 PRP81045.1 - 1.5 9.2 28.3 0.22 11.9 1.6 5.0 4 2 1 5 5 5 0 Plant protein of unknown function (DUF641) Beta_protein PF14350.6 PRP81046.1 - 0.18 11.2 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Beta protein PTPA PF03095.15 PRP81050.1 - 2e-91 306.6 0.0 2.2e-91 306.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DnaJ PF00226.31 PRP81051.1 - 1.8e-14 53.6 0.0 3.3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain F-box PF00646.33 PRP81051.1 - 0.0048 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP81051.1 - 0.0093 15.8 1.5 0.0093 15.8 0.0 1.8 2 0 0 2 2 2 1 F-box-like cPLA2_C2 PF18695.1 PRP81051.1 - 0.026 14.5 1.5 0.04 13.9 0.2 1.9 2 0 0 2 2 2 0 Cytosolic phospholipases A2 C2-domain RPT PF13446.6 PRP81051.1 - 0.03 14.2 0.0 0.075 13.0 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein Inhibitor_I67 PF11405.8 PRP81051.1 - 0.23 11.8 2.4 0.53 10.6 2.4 1.6 1 0 0 1 1 1 0 Bromelain inhibitor VI IBR PF01485.21 PRP81051.1 - 6.4 7.1 10.1 19 5.5 7.0 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Translin PF01997.16 PRP81052.1 - 1.6e-44 152.4 0.2 1.8e-44 152.2 0.2 1.0 1 0 0 1 1 1 1 Translin family Laminin_II PF06009.12 PRP81052.1 - 0.0042 17.1 0.1 0.023 14.7 0.1 2.0 2 0 0 2 2 2 1 Laminin Domain II DUF1664 PF07889.12 PRP81052.1 - 0.0076 16.3 0.4 0.28 11.2 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Rab5-bind PF09311.11 PRP81052.1 - 0.0082 15.6 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Rabaptin-like protein DUF948 PF06103.11 PRP81052.1 - 0.025 14.9 0.1 0.067 13.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 PRP81052.1 - 0.095 13.2 0.2 1.5 9.4 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 PRP81052.1 - 0.11 12.7 1.1 0.15 12.3 0.4 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 PRP81052.1 - 0.32 11.1 1.5 0.68 10.0 0.6 2.0 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IBR PF01485.21 PRP81053.1 - 1.4e-14 54.1 44.7 9.6e-10 38.5 12.3 4.2 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 PRP81053.1 - 0.00028 21.2 0.0 0.001 19.4 0.0 2.0 1 0 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 PRP81053.1 - 0.00051 19.8 7.2 0.00051 19.8 7.2 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP81053.1 - 0.00056 19.7 9.1 0.00056 19.7 9.1 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP81053.1 - 0.00073 19.8 10.4 0.00073 19.8 10.4 3.8 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PRP81053.1 - 0.0025 17.8 11.0 0.0025 17.8 11.0 3.7 3 0 0 3 3 3 1 zinc-RING finger domain DUF5333 PF17267.2 PRP81053.1 - 0.016 15.4 0.2 0.048 13.8 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5333) Cofilin_ADF PF00241.20 PRP81054.1 - 1.9e-54 182.6 0.0 8.7e-18 64.3 0.0 3.1 3 0 0 3 3 3 3 Cofilin/tropomyosin-type actin-binding protein AIM24 PF01987.17 PRP81055.1 - 1.2e-40 139.4 1.2 1.8e-40 138.9 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 WWE PF02825.20 PRP81055.1 - 1.1e-08 35.5 1.5 2.9e-08 34.2 1.5 1.8 1 0 0 1 1 1 1 WWE domain Linker_histone PF00538.19 PRP81055.1 - 0.00015 22.0 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Macro PF01661.21 PRP81056.1 - 9.2e-31 106.3 0.0 4.5e-30 104.1 0.0 2.1 2 0 0 2 2 2 1 Macro domain Lar_restr_allev PF14354.6 PRP81056.1 - 0.09 13.2 0.1 0.25 11.8 0.1 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar WD40 PF00400.32 PRP81057.1 - 8.3e-20 70.8 12.6 5.9e-05 23.8 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP81057.1 - 1.1e-05 25.7 0.0 0.95 9.8 0.0 4.4 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PRP81057.1 - 0.0014 19.0 0.3 0.55 10.8 0.1 3.9 4 0 0 4 4 4 1 PQQ-like domain Cytochrom_D1 PF02239.16 PRP81057.1 - 0.0039 15.8 0.2 0.054 12.0 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain BBS2_N PF14781.6 PRP81057.1 - 0.078 12.9 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal PARP PF00644.20 PRP81058.1 - 5e-38 130.7 0.0 9.1e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Josephin PF02099.17 PRP81058.1 - 1.1e-32 113.4 0.6 2.5e-32 112.2 0.6 1.6 1 0 0 1 1 1 1 Josephin PARP_reg PF02877.14 PRP81058.1 - 1.4e-14 54.4 0.0 4.7e-14 52.7 0.0 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Ank_2 PF12796.7 PRP81058.1 - 6.3e-08 33.1 0.1 0.02 15.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) WGR PF05406.15 PRP81058.1 - 0.0077 16.3 0.0 0.025 14.6 0.0 2.0 1 0 0 1 1 1 1 WGR domain SAP PF02037.27 PRP81058.1 - 0.01 15.6 1.4 0.016 15.0 0.1 2.1 2 0 0 2 2 2 0 SAP domain LEA_4 PF02987.16 PRP81062.1 - 2.2e-06 27.6 24.2 2.2e-06 27.6 24.2 8.1 1 1 6 7 7 7 4 Late embryogenesis abundant protein DUF883 PF05957.13 PRP81062.1 - 9.2e-05 23.0 67.3 0.12 13.0 8.3 5.2 1 1 5 6 6 6 4 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 PRP81062.1 - 0.00055 19.9 47.9 0.017 15.0 24.0 2.6 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 PRP81062.1 - 0.022 15.3 70.3 1.8e+04 -8.3 30.0 5.7 1 1 1 2 2 2 0 YtxH-like protein ApoO PF09769.9 PRP81062.1 - 0.095 12.7 14.6 0.94 9.4 0.8 3.7 1 1 1 3 3 3 0 Apolipoprotein O LMBR1 PF04791.16 PRP81062.1 - 0.2 10.5 4.9 0.22 10.4 4.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein ApoLp-III PF07464.11 PRP81062.1 - 1.6 8.9 41.7 6.1 6.9 5.7 3.4 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) HSP9_HSP12 PF04119.12 PRP81062.1 - 4.9 7.6 47.6 0.37 11.2 1.4 7.8 1 1 6 7 7 7 0 Heat shock protein 9/12 Nucleopor_Nup85 PF07575.13 PRP81063.1 - 3.8e-58 197.4 8.0 5.5e-58 196.9 8.0 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin Self-incomp_S1 PF05938.11 PRP81064.1 - 0.097 13.2 0.5 0.38 11.3 0.5 2.0 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 Ras PF00071.22 PRP81065.1 - 8.3e-50 168.5 0.0 9.7e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP81065.1 - 2.3e-18 66.6 0.0 3.5e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP81065.1 - 3.9e-07 29.7 0.0 4.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP81065.1 - 5.3e-05 23.2 0.4 0.14 12.1 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP81065.1 - 0.027 14.0 0.2 0.55 9.7 0.0 2.3 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP81065.1 - 0.048 13.7 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 PRP81065.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 PRP81065.1 - 0.24 11.1 0.5 3.6 7.3 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Dynamin_M PF01031.20 PRP81066.1 - 1.1e-105 353.0 0.0 2.9e-105 351.6 0.0 1.8 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 PRP81066.1 - 1.8e-57 194.1 0.0 4.3e-57 192.8 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 PRP81066.1 - 9.7e-32 109.0 5.2 3.4e-31 107.2 5.2 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 PRP81066.1 - 2.3e-05 24.4 0.1 9.3e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 PRP81066.1 - 0.04 13.7 0.1 0.086 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PRP81066.1 - 0.05 13.3 3.7 0.19 11.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 PRP81066.1 - 0.074 13.3 0.0 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Phasin PF05597.11 PRP81066.1 - 1 9.4 4.0 0.56 10.2 0.2 2.5 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CBFD_NFYB_HMF PF00808.23 PRP81067.1 - 4.2e-19 68.6 1.2 7.3e-19 67.8 1.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PRP81067.1 - 1.9e-13 50.9 0.2 1.9e-13 50.9 0.2 1.9 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 PRP81067.1 - 0.067 13.3 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region PAP1 PF08601.10 PRP81068.1 - 0.31 10.7 9.2 0.35 10.5 9.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Arginase PF00491.21 PRP81069.1 - 4.8e-46 157.5 0.0 5.5e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family Gemini_AC4_5 PF04807.12 PRP81069.1 - 0.16 11.7 0.3 0.33 10.7 0.3 1.5 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region RasGEF PF00617.19 PRP81071.1 - 4.7e-46 157.2 0.1 1e-45 156.1 0.1 1.6 1 0 0 1 1 1 1 RasGEF domain PH PF00169.29 PRP81071.1 - 2.6e-19 69.7 0.8 1.3e-18 67.4 0.3 2.3 2 0 0 2 2 2 1 PH domain RasGEF_N PF00618.20 PRP81071.1 - 1.1e-14 54.6 0.3 1.1e-14 54.6 0.3 2.6 3 0 0 3 3 3 1 RasGEF N-terminal motif PH_8 PF15409.6 PRP81071.1 - 3.9e-06 27.0 0.9 1.1e-05 25.6 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PRP81071.1 - 2.9e-05 24.1 0.1 8.6e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 PRP81071.1 - 0.00045 20.5 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PRP81071.1 - 0.0023 18.3 7.9 0.0091 16.4 4.3 3.5 2 2 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 PRP81071.1 - 0.0035 17.7 1.6 0.27 11.6 0.7 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain DNA_topoisoIV PF00521.20 PRP81072.1 - 2.1e-125 419.0 0.4 7e-125 417.3 0.4 2.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 PRP81072.1 - 3.6e-47 159.8 0.8 3.6e-47 159.8 0.8 2.6 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 PRP81072.1 - 1.7e-21 76.5 0.2 1.7e-21 76.5 0.2 2.9 3 0 0 3 3 3 1 DNA gyrase B VPS9 PF02204.18 PRP81072.1 - 2.2e-14 53.5 0.0 6.1e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HATPase_c PF02518.26 PRP81072.1 - 1.2e-12 48.3 0.7 7.2e-12 45.8 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LRR_6 PF13516.6 PRP81072.1 - 1e-10 40.8 9.5 0.12 12.5 0.3 4.9 4 0 0 4 4 4 4 Leucine Rich repeat Toprim PF01751.22 PRP81072.1 - 3.7e-08 33.5 0.0 4.3e-07 30.1 0.0 3.0 2 0 0 2 2 2 1 Toprim domain LRR_4 PF12799.7 PRP81072.1 - 0.024 15.1 2.0 2 9.0 1.2 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_hydro_98C PF08307.11 PRP81072.1 - 0.034 13.6 1.8 1.5 8.2 0.1 3.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 98 C-terminal domain GMP_PDE_delta PF05351.11 PRP81073.1 - 7.1e-20 71.7 0.2 3.3e-19 69.5 0.2 1.9 1 1 0 1 1 1 1 GMP-PDE, delta subunit X8 PF07983.13 PRP81074.1 - 2.2e-52 175.6 53.8 3.4e-10 40.4 2.3 6.7 6 0 0 6 6 6 6 X8 domain Ribosomal_S30 PF04758.14 PRP81074.1 - 6.4e-18 64.7 7.0 6.4e-18 64.7 7.0 2.9 3 0 0 3 3 3 1 Ribosomal protein S30 Exo_endo_phos PF03372.23 PRP81074.1 - 1.3e-17 64.1 0.0 4.2e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_17 PF00332.18 PRP81074.1 - 5e-06 26.3 2.0 8.6e-06 25.6 0.8 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF226 PF02890.14 PRP81074.1 - 0.00086 19.3 2.6 2 8.4 0.0 4.1 4 0 0 4 4 4 2 Borrelia family of unknown function DUF226 DUF2989 PF11207.8 PRP81074.1 - 0.021 14.6 9.0 1.4 8.6 0.0 5.4 6 1 1 7 7 7 0 Protein of unknown function (DUF2989) DUF61 PF01886.16 PRP81074.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF61 WD40 PF00400.32 PRP81075.1 - 6.4e-65 213.5 33.9 2.1e-10 41.0 0.2 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP81075.1 - 6.2e-23 80.9 2.1 4.8e-06 26.8 0.2 5.3 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP81075.1 - 3.5e-12 45.7 3.6 0.039 12.6 0.0 6.1 2 2 4 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PRP81075.1 - 4.9e-07 28.8 2.1 0.00031 19.6 0.1 3.3 2 2 2 4 4 4 2 Nup133 N terminal like LisH PF08513.11 PRP81075.1 - 0.00014 21.6 0.1 0.00025 20.9 0.1 1.4 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 PRP81075.1 - 0.00037 19.6 11.4 0.02 13.9 0.1 4.8 1 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH_TPL PF17814.1 PRP81075.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 LisH-like dimerisation domain Frtz PF11768.8 PRP81075.1 - 0.032 12.5 0.1 0.24 9.7 0.0 2.2 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz bZIP_2 PF07716.15 PRP81075.1 - 0.069 13.2 0.7 0.14 12.3 0.7 1.4 1 0 0 1 1 1 0 Basic region leucine zipper nos_propeller PF18764.1 PRP81075.1 - 0.1 12.6 0.1 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat FapA PF03961.13 PRP81075.1 - 1.7 7.1 3.0 2.5 6.6 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A IFT57 PF10498.9 PRP81076.1 - 1.7e-111 372.7 5.0 2.3e-111 372.3 5.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 LRR_8 PF13855.6 PRP81076.1 - 1.5e-17 63.1 16.8 2.6e-07 30.3 0.2 4.8 3 2 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 PRP81076.1 - 1.4e-15 57.2 24.0 1.5e-05 25.2 5.9 5.9 1 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP81076.1 - 8.7e-05 22.6 13.2 11 7.1 0.1 7.4 9 0 0 9 9 6 1 Leucine Rich Repeat Spc7 PF08317.11 PRP81076.1 - 0.13 11.1 9.6 0.26 10.1 9.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 PRP81076.1 - 0.18 11.8 7.9 0.29 11.2 2.7 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 PRP81076.1 - 0.2 11.6 0.1 0.2 11.6 0.1 3.5 3 1 1 4 4 4 0 Prefoldin subunit DUF148 PF02520.17 PRP81076.1 - 0.66 10.1 6.8 0.2 11.8 1.1 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF1664 PF07889.12 PRP81076.1 - 0.71 9.9 8.5 4 7.5 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4472 PF14739.6 PRP81076.1 - 1.3 9.8 11.3 3.3 8.5 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) LRR_6 PF13516.6 PRP81076.1 - 1.5 9.1 26.3 0.31 11.2 0.2 5.8 7 0 0 7 7 6 0 Leucine Rich repeat DUF2508 PF10704.9 PRP81076.1 - 1.7 8.9 7.5 0.63 10.3 0.4 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF2508) Fib_alpha PF08702.10 PRP81076.1 - 1.9 8.7 8.1 8.1 6.6 7.8 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 PRP81076.1 - 4.6 7.6 6.1 34 4.8 5.1 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Mito_carr PF00153.27 PRP81078.1 - 1.1e-59 198.4 3.4 3.5e-23 81.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PRP81078.1 - 0.22 10.7 0.9 1.2 8.2 0.1 2.6 1 1 2 3 3 3 0 Gammaproteobacterial serine protease Med27 PF11571.8 PRP81079.1 - 8.7e-14 51.7 0.2 5.9e-13 49.0 0.1 2.1 2 0 0 2 2 2 1 Mediator complex subunit 27 TERF2_RBM PF16772.5 PRP81079.1 - 0.0091 15.4 0.2 0.023 14.1 0.2 1.7 1 0 0 1 1 1 1 Telomeric repeat-binding factor 2 Rap1-binding motif CLU PF13236.6 PRP81080.1 - 1e-50 172.7 0.0 2.8e-50 171.2 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria Lipase_GDSL PF00657.22 PRP81080.1 - 0.0043 17.0 0.0 0.51 10.3 0.0 2.3 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase ECSIT PF06239.11 PRP81080.1 - 0.045 12.9 1.7 0.11 11.7 0.8 1.9 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway FAM60A PF15396.6 PRP81080.1 - 0.74 9.8 5.9 2 8.3 5.9 1.9 1 1 0 1 1 1 0 Protein Family FAM60A TCTP PF00838.17 PRP81080.1 - 1.2 9.5 11.8 0.83 10.0 7.7 2.7 2 1 1 3 3 3 0 Translationally controlled tumour protein PseudoU_synth_2 PF00849.22 PRP81081.1 - 1.3e-07 31.8 0.4 0.00095 19.3 0.0 2.4 2 0 0 2 2 2 2 RNA pseudouridylate synthase AAA PF00004.29 PRP81082.1 - 5.8e-16 59.1 0.0 1.1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP81082.1 - 7.4e-07 29.5 0.0 9.9e-05 22.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PRP81082.1 - 1e-05 25.6 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP81082.1 - 0.00015 22.2 0.0 0.00064 20.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 PRP81082.1 - 0.00047 20.0 3.3 0.0047 16.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PRP81082.1 - 0.0092 16.3 0.0 0.44 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP81082.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PRP81082.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Nop14 PF04147.12 PRP81082.1 - 0.013 13.8 7.8 0.018 13.3 7.8 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_33 PF13671.6 PRP81082.1 - 0.037 14.2 0.0 0.094 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PRP81082.1 - 0.049 13.9 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PRP81082.1 - 0.051 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 PRP81082.1 - 0.066 12.4 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 PRP81082.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 PRP81082.1 - 0.12 11.9 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DNA_pol_phi PF04931.13 PRP81082.1 - 0.93 7.5 14.4 1.8 6.5 14.4 1.4 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 PRP81082.1 - 0.99 8.7 8.7 1.7 8.0 8.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 PRP81082.1 - 1.5 8.2 12.3 2.4 7.5 12.3 1.3 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 PRP81082.1 - 3 8.3 12.1 6.9 7.1 12.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 PRP81082.1 - 8.5 5.6 12.2 15 4.8 12.2 1.3 1 0 0 1 1 1 0 NOA36 protein Aldo_ket_red PF00248.21 PRP81083.1 - 2e-42 145.4 0.0 2.6e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LBP_BPI_CETP_C PF02886.17 PRP81084.1 - 2.7e-37 128.5 0.0 4.4e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain Lip_prot_lig_C PF10437.9 PRP81084.1 - 0.012 15.6 0.3 0.32 11.0 0.1 2.6 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus LBP_BPI_CETP PF01273.25 PRP81085.1 - 2.1e-09 37.2 0.1 2.9e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Pribosyltran_N PF13793.6 PRP81086.1 - 4.3e-07 29.9 0.0 8.1e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 PRP81086.1 - 9e-07 28.5 0.1 2.2e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 PRP81086.1 - 0.002 18.2 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain PRKCSH-like PF12999.7 PRP81087.1 - 1.9e-36 125.5 9.4 5.5e-36 124.0 9.4 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 PRP81087.1 - 6.7e-24 84.3 3.1 8.4e-24 84.0 0.1 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 PRP81087.1 - 2.4e-08 34.9 2.2 2.4e-08 34.9 2.2 2.5 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 PRP81087.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 2.3 2 0 0 2 2 2 1 Autophagy-related protein 27 HBM PF16591.5 PRP81087.1 - 0.0018 17.7 1.3 0.0018 17.7 1.3 1.5 2 0 0 2 2 2 1 Helical bimodular sensor domain AAA_13 PF13166.6 PRP81087.1 - 0.036 12.7 4.5 0.057 12.1 4.5 1.2 1 0 0 1 1 1 0 AAA domain Ldl_recept_a PF00057.18 PRP81087.1 - 0.049 13.9 17.5 0.55 10.5 5.5 2.8 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A DUF4226 PF10774.9 PRP81087.1 - 0.081 13.2 3.4 1.4 9.2 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) DUF2986 PF11661.8 PRP81087.1 - 0.085 13.4 0.6 0.19 12.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) HR1 PF02185.16 PRP81087.1 - 0.24 11.5 9.0 0.65 10.1 3.9 2.7 2 1 0 2 2 2 0 Hr1 repeat CCDC53 PF10152.9 PRP81087.1 - 4.4 7.7 13.2 9 6.7 13.2 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TMF_DNA_bd PF12329.8 PRP81087.1 - 7.1 6.7 20.8 0.61 10.1 8.1 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding RhoGEF PF00621.20 PRP81088.1 - 6.2e-38 130.9 0.4 1.2e-37 129.9 0.4 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_16 PF17838.1 PRP81088.1 - 0.00049 19.9 0.8 0.019 14.8 0.1 2.4 2 0 0 2 2 2 1 PH domain CENP-F_leu_zip PF10473.9 PRP81088.1 - 0.0044 17.1 5.0 0.014 15.4 2.1 2.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 PRP81088.1 - 0.0049 17.2 2.6 0.082 13.3 0.8 3.2 2 1 1 3 3 2 1 Flagella accessory protein C (FlaC) PH_5 PF15405.6 PRP81088.1 - 0.0054 16.8 0.4 0.016 15.3 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain DUF812 PF05667.11 PRP81088.1 - 0.0068 15.3 3.1 0.01 14.7 3.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) NleF_casp_inhib PF16809.5 PRP81088.1 - 0.014 15.3 1.0 0.023 14.6 0.1 1.8 2 0 0 2 2 2 0 NleF caspase inhibitor DUF16 PF01519.16 PRP81088.1 - 0.027 14.9 0.2 0.13 12.8 0.1 2.2 2 0 0 2 2 1 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 PRP81088.1 - 0.03 14.3 4.1 0.12 12.3 1.0 2.9 2 1 0 2 2 2 0 Prefoldin subunit PspA_IM30 PF04012.12 PRP81088.1 - 0.031 13.9 0.8 0.055 13.0 0.8 1.4 1 0 0 1 1 1 0 PspA/IM30 family PH PF00169.29 PRP81088.1 - 0.033 14.7 0.8 0.24 12.0 0.4 2.5 2 1 0 2 2 1 0 PH domain CCDC-167 PF15188.6 PRP81088.1 - 0.049 14.0 3.1 0.19 12.1 3.1 2.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3450 PF11932.8 PRP81088.1 - 0.058 12.7 0.4 0.12 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 PRP81088.1 - 0.15 12.3 8.6 0.25 11.6 8.1 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 PRP81088.1 - 0.17 12.0 3.3 0.16 12.1 0.4 2.5 3 0 0 3 3 2 0 bZIP transcription factor DUF2730 PF10805.8 PRP81088.1 - 0.19 11.8 2.3 10 6.3 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) WD40_alt PF14077.6 PRP81088.1 - 0.22 11.4 1.7 2.6 8.0 0.9 2.7 1 1 1 2 2 2 0 Alternative WD40 repeat motif BST2 PF16716.5 PRP81088.1 - 0.28 11.8 2.8 1 10.0 2.8 1.9 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF2968 PF11180.8 PRP81088.1 - 0.67 9.6 6.3 0.42 10.2 2.7 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) Tropomyosin_1 PF12718.7 PRP81088.1 - 1.5 9.0 7.5 0.31 11.2 2.0 2.7 3 0 0 3 3 3 0 Tropomyosin like DUF4094 PF13334.6 PRP81088.1 - 2.7 8.4 5.0 1.4 9.4 1.1 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) Trimer_CC PF08954.11 PRP81088.1 - 8.4 6.0 9.4 22 4.7 0.0 4.3 3 1 1 4 4 4 0 Trimerisation motif NinF PF05810.12 PRP81089.1 - 0.025 14.5 0.2 0.046 13.6 0.2 1.4 1 0 0 1 1 1 0 NinF protein Rap_GAP PF02145.15 PRP81091.1 - 1.5e-57 194.1 0.0 5.2e-57 192.4 0.0 1.9 2 0 0 2 2 2 1 Rap/ran-GAP PH PF00169.29 PRP81091.1 - 1.7e-08 34.9 0.1 3.2e-07 30.8 0.0 3.0 2 0 0 2 2 2 1 PH domain AhpC-TSA_2 PF13911.6 PRP81091.1 - 2.9e-08 33.8 0.0 8.6e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme PH_8 PF15409.6 PRP81091.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain AhpC-TSA PF00578.21 PRP81091.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family ECD PF18432.1 PRP81091.1 - 0.018 15.0 0.0 0.12 12.3 0.0 2.3 2 1 0 2 2 2 0 Extracellular Cadherin domain Redoxin PF08534.10 PRP81091.1 - 0.025 14.3 2.2 0.04 13.6 0.0 2.4 3 0 0 3 3 3 0 Redoxin CDC27 PF09507.10 PRP81091.1 - 1.7 8.0 34.8 0.11 11.9 29.3 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Complex1_LYR PF05347.15 PRP81092.1 - 0.0019 18.2 0.0 0.0019 18.2 0.0 2.5 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Methyltransf_31 PF13847.6 PRP81095.1 - 1.3e-10 41.3 0.0 2.7e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP81095.1 - 6.4e-09 35.6 0.0 1.7e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP81095.1 - 6.2e-08 33.2 0.0 1.9e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP81095.1 - 8.3e-07 28.7 0.1 1.9e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 PRP81095.1 - 1.1e-05 25.2 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 PRP81095.1 - 1.1e-05 25.3 0.0 0.00035 20.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PRP81095.1 - 1.5e-05 24.8 0.0 0.0017 18.0 0.0 2.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 PRP81095.1 - 2.2e-05 25.0 0.0 7.5e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 PRP81095.1 - 5.9e-05 22.5 0.0 9.8e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase PCMT PF01135.19 PRP81095.1 - 0.00019 21.3 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 PRP81095.1 - 0.00081 19.0 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 PRP81095.1 - 0.0053 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 PRP81095.1 - 0.0069 16.3 0.0 0.025 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain S4 PF01479.25 PRP81095.1 - 0.0091 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain MetW PF07021.12 PRP81095.1 - 0.0097 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_10 PF05971.12 PRP81095.1 - 0.012 15.0 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA methyltransferase Methyltransf_12 PF08242.12 PRP81095.1 - 0.023 15.5 0.0 0.054 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 PRP81095.1 - 0.077 14.0 0.0 1.2 10.2 0.0 2.8 3 1 0 3 3 2 0 Methyltransferase domain Eco57I PF07669.11 PRP81095.1 - 0.14 12.7 0.0 0.42 11.1 0.0 1.8 1 0 0 1 1 1 0 Eco57I restriction-modification methylase RasGAP PF00616.19 PRP81097.1 - 7.4e-16 58.5 0.7 2.1e-11 43.9 0.1 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase TPR_19 PF14559.6 PRP81097.1 - 1.4e-13 51.1 3.8 0.017 15.6 0.1 8.6 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP81097.1 - 3.7e-12 45.4 16.9 0.2 11.9 0.3 8.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 PRP81097.1 - 1.1e-09 38.4 6.0 0.11 12.8 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP81097.1 - 9.2e-07 29.2 10.3 15 6.7 0.0 9.1 8 2 2 10 10 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP81097.1 - 3.2e-06 26.7 13.9 1.1 9.2 0.2 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP81097.1 - 5.4e-06 26.9 10.9 0.071 13.8 0.8 6.5 6 2 0 7 7 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP81097.1 - 0.00014 22.3 9.2 24 5.9 0.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP81097.1 - 0.00017 21.6 13.0 12 6.4 0.0 8.1 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 PRP81097.1 - 0.0011 19.3 1.7 0.35 11.2 0.0 3.4 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP81097.1 - 0.0011 18.6 10.8 0.33 10.7 0.5 6.0 7 0 0 7 7 7 1 TPR repeat ANAPC3 PF12895.7 PRP81097.1 - 0.0011 19.1 12.9 0.11 12.7 0.8 6.0 4 2 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 PRP81097.1 - 0.0014 18.4 0.7 0.24 11.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain YfiO PF13525.6 PRP81097.1 - 0.0093 15.7 1.5 1.8 8.3 0.1 3.1 3 0 0 3 3 3 1 Outer membrane lipoprotein SHNi-TPR PF10516.9 PRP81097.1 - 0.023 14.1 0.1 0.083 12.4 0.1 1.9 1 0 0 1 1 1 0 SHNi-TPR TPR_17 PF13431.6 PRP81097.1 - 0.07 13.5 6.0 52 4.5 0.8 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP81097.1 - 0.19 11.8 3.9 2.5 8.2 0.2 3.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat CoA_transf_3 PF02515.17 PRP81098.1 - 6.7e-76 255.8 0.0 1.6e-75 254.6 0.0 1.6 1 0 0 1 1 1 1 CoA-transferase family III HATPase_c PF02518.26 PRP81098.1 - 4.2e-26 91.6 0.2 1.1e-25 90.3 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP81098.1 - 4.2e-23 81.7 1.5 6.6e-20 71.4 0.2 3.3 2 1 0 2 2 2 2 Response regulator receiver domain RhoGAP PF00620.27 PRP81098.1 - 1.8e-08 34.3 0.1 1.8e-08 34.3 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain HisKA PF00512.25 PRP81098.1 - 0.0001 22.3 0.5 0.00092 19.2 0.1 3.0 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain ATC_hydrolase PF14196.6 PRP81099.1 - 3.8e-08 34.2 0.0 7.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase SWIRM-assoc_1 PF16495.5 PRP81099.1 - 0.021 14.8 0.9 0.044 13.7 0.9 1.4 1 0 0 1 1 1 0 SWIRM-associated region 1 MetOD1 PF18546.1 PRP81099.1 - 0.029 14.3 0.4 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 Metanogen output domain 1 Rap_GAP PF02145.15 PRP81101.1 - 6.7e-62 208.3 0.0 2.8e-61 206.3 0.0 2.1 3 0 0 3 3 3 1 Rap/ran-GAP cNMP_binding PF00027.29 PRP81101.1 - 2.7e-24 85.0 0.1 2.6e-10 40.2 0.0 3.5 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain DEP PF00610.21 PRP81101.1 - 4.1e-22 78.0 0.1 9.7e-22 76.8 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 PRP81101.1 - 0.00049 20.6 0.2 0.0047 17.4 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 PRP81101.1 - 0.011 15.5 0.2 0.025 14.4 0.2 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain MIase PF02426.16 PRP81101.1 - 0.093 12.9 0.6 0.37 11.0 0.0 2.3 2 0 0 2 2 2 0 Muconolactone delta-isomerase YjeF_N PF03853.15 PRP81102.1 - 1.2e-18 67.6 0.0 1.5e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PAS_3 PF08447.12 PRP81103.1 - 1.3e-09 38.3 0.0 1.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 PRP81103.1 - 2e-05 24.8 0.0 0.00039 20.6 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 PRP81103.1 - 0.00082 19.3 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 PRP81103.1 - 0.0035 17.6 0.0 0.014 15.6 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 PRP81103.1 - 0.0071 16.3 0.0 0.037 14.0 0.0 2.0 2 0 0 2 2 2 1 PAS fold Exo_endo_phos PF03372.23 PRP81105.1 - 5.7e-06 26.0 0.0 4.6e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GTP_EFTU PF00009.27 PRP81106.1 - 1.6e-45 155.0 0.0 2.4e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 PRP81106.1 - 1.3e-27 96.8 4.4 2.6e-27 95.8 4.4 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 PRP81106.1 - 1.4e-24 85.9 0.0 3.6e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 PRP81106.1 - 8.3e-19 67.6 0.0 2.2e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 PRP81106.1 - 4.2e-10 39.9 0.0 9.4e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PRP81106.1 - 2.8e-06 27.4 0.1 5.3e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 PRP81106.1 - 3e-06 27.2 0.1 7.4e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Dynamin_N PF00350.23 PRP81106.1 - 0.0033 17.5 0.1 3 7.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Ras PF00071.22 PRP81106.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Ras family SRPRB PF09439.10 PRP81106.1 - 0.016 14.7 0.1 0.043 13.3 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PRP81106.1 - 0.028 14.3 1.2 3 7.7 0.2 3.1 1 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 PRP81106.1 - 0.038 14.2 0.0 0.27 11.5 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 PRP81106.1 - 0.094 12.3 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LRR_8 PF13855.6 PRP81107.1 - 1e-17 63.6 52.6 1.5e-06 27.9 4.5 7.4 4 2 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 PRP81107.1 - 8.9e-17 60.9 61.8 9.4e-08 32.2 2.0 9.7 4 3 6 11 11 11 8 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP81107.1 - 3.2e-15 56.1 0.3 1.2e-14 54.2 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81107.1 - 7.9e-10 38.5 0.0 4.8e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP81107.1 - 1.9e-09 37.9 4.7 1.9e-09 37.9 4.7 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_9 PF14580.6 PRP81107.1 - 0.00065 19.2 13.1 0.0014 18.1 1.1 3.2 3 0 0 3 3 3 2 Leucine-rich repeat A_thal_3526 PF09713.10 PRP81108.1 - 1e-16 60.9 0.2 1.7e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) Peptidase_C6 PF00851.18 PRP81108.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Helper component proteinase FAD_binding_1 PF00667.20 PRP81109.1 - 2.8e-48 164.4 0.0 4.1e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PRP81109.1 - 5.3e-29 101.3 0.0 9.5e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 PRP81109.1 - 4.6e-10 40.1 0.0 1.2e-09 38.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 PRP81109.1 - 5.4e-06 26.7 0.2 0.05 13.8 0.0 2.6 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_3 PF12641.7 PRP81109.1 - 0.047 13.4 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain ClpS PF02617.17 PRP81109.1 - 0.12 12.2 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS zf-RVT PF13966.6 PRP81112.1 - 0.0054 17.4 0.6 0.015 16.0 0.5 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase UPF0147 PF03685.13 PRP81112.1 - 0.12 12.4 0.2 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) RVT_1 PF00078.27 PRP81113.1 - 1.5e-05 24.7 0.0 0.00098 18.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 PRP81113.1 - 0.0081 16.4 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF1027 PF06265.11 PRP81115.1 - 0.12 12.4 0.1 3.3 7.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1027) SNAPc_SNAP43 PF09808.9 PRP81116.1 - 0.0045 16.9 1.4 0.0061 16.5 1.4 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Tweety PF04906.13 PRP81116.1 - 0.006 15.3 0.3 0.01 14.6 0.1 1.4 1 1 1 2 2 2 1 Tweety Snapin_Pallidin PF14712.6 PRP81116.1 - 0.031 14.7 3.0 0.059 13.8 1.4 2.1 1 1 0 2 2 2 0 Snapin/Pallidin Esterase PF00756.20 PRP81118.1 - 2.6e-56 191.1 0.2 3.3e-56 190.8 0.2 1.1 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 PRP81118.1 - 1.5e-05 24.4 0.1 5.4e-05 22.6 0.1 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PRP81118.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 PRP81118.1 - 0.021 13.8 0.0 0.036 13.0 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme DUF3718 PF12514.8 PRP81118.1 - 0.021 15.0 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) Abhydrolase_1 PF00561.20 PRP81118.1 - 0.025 14.2 0.1 0.047 13.3 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP81118.1 - 0.078 13.6 0.0 0.21 12.2 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4574 PF15141.6 PRP81118.1 - 0.17 11.8 0.4 0.43 10.5 0.4 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF2415 PF10313.9 PRP81120.1 - 1.2e-13 50.7 0.7 6.7e-13 48.3 0.1 2.6 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 PRP81120.1 - 0.009 16.9 4.9 0.64 11.0 0.9 4.1 4 1 0 4 4 4 1 WD domain, G-beta repeat KxDL PF10241.9 PRP81121.1 - 2.1e-16 59.9 3.4 3.1e-16 59.4 3.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF3106 PF11304.8 PRP81121.1 - 0.026 15.0 1.4 0.033 14.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Spore_III_AB PF09548.10 PRP81121.1 - 0.049 13.8 0.8 0.053 13.6 0.8 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF241 PF03087.14 PRP81121.1 - 0.071 12.9 0.9 0.095 12.5 0.9 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Ribosomal_L7Ae PF01248.26 PRP81122.1 - 1.7e-22 79.0 0.9 3.1e-22 78.1 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 PRP81122.1 - 0.085 12.9 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 RNase P subunit Pop3 DUF4105 PF13387.6 PRP81122.1 - 0.18 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Pkinase PF00069.25 PRP81123.1 - 5e-10 39.2 0.0 2e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 PRP81123.1 - 2.5e-06 27.5 0.1 0.00011 22.3 0.0 2.4 1 1 1 2 2 2 1 PH domain Pkinase_Tyr PF07714.17 PRP81123.1 - 0.011 15.0 0.1 0.043 13.1 0.1 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase TPR_1 PF00515.28 PRP81124.1 - 0.00013 21.7 1.0 0.032 14.1 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP81124.1 - 0.0012 18.8 0.6 7.3 7.0 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Methyltransf_23 PF13489.6 PRP81124.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP81124.1 - 0.019 15.7 0.0 0.047 14.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 PRP81124.1 - 0.026 15.2 0.0 0.061 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 PRP81124.1 - 0.11 13.3 0.0 0.23 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.28 PRP81125.1 - 1.1e-35 124.0 0.1 1.5e-35 123.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 PRP81125.1 - 0.0034 17.1 0.0 0.0051 16.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain gag-asp_proteas PF13975.6 PRP81126.1 - 7.3e-05 23.3 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 PRP81126.1 - 0.00099 18.9 0.1 0.0016 18.2 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 PRP81126.1 - 0.069 13.8 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease SRP54 PF00448.22 PRP81127.1 - 2e-55 187.5 0.5 4.2e-55 186.4 0.5 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 PRP81127.1 - 2.1e-32 113.3 14.8 6.6e-32 111.6 14.8 1.7 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 PRP81127.1 - 1e-07 32.1 2.0 1.5e-07 31.6 0.0 2.5 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 PRP81127.1 - 6.7e-05 23.3 0.0 0.00033 21.1 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain CbiA PF01656.23 PRP81127.1 - 0.00013 22.1 1.0 0.0019 18.2 1.1 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 PRP81127.1 - 0.00027 20.9 0.7 0.023 14.6 0.3 2.8 2 1 0 2 2 1 1 NTPase AAA_30 PF13604.6 PRP81127.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thiamine_BP PF01910.17 PRP81127.1 - 0.0034 17.3 0.1 0.053 13.4 0.0 2.5 2 0 0 2 2 2 1 Thiamine-binding protein AAA_17 PF13207.6 PRP81127.1 - 0.0043 17.5 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 PRP81127.1 - 0.0049 15.9 0.0 0.019 14.0 0.0 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 PRP81127.1 - 0.0053 16.1 0.0 0.0097 15.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 PRP81127.1 - 0.019 15.3 0.1 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Peripla_BP_4 PF13407.6 PRP81127.1 - 0.032 13.8 1.1 0.34 10.4 0.2 2.4 2 1 1 3 3 3 0 Periplasmic binding protein domain Fer4_NifH PF00142.18 PRP81127.1 - 0.035 13.5 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA PF00004.29 PRP81127.1 - 0.039 14.4 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 PRP81127.1 - 0.059 13.5 2.9 0.1 12.7 0.5 2.6 2 2 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.6 PRP81127.1 - 0.066 13.5 0.3 0.64 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 PRP81127.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Inhibitor_I78 PF11720.8 PRP81127.1 - 0.12 12.5 0.0 9.8 6.3 0.0 3.3 4 0 0 4 4 4 0 Peptidase inhibitor I78 family HA2 PF04408.23 PRP81128.1 - 2.5e-25 88.9 0.1 2.5e-25 88.9 0.1 5.5 4 1 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PRP81128.1 - 4.7e-16 58.9 0.0 5.6e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PRP81128.1 - 9.6e-11 42.0 0.2 4.2e-09 36.7 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP81128.1 - 1.3e-09 38.1 0.0 3.2e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PPR_2 PF13041.6 PRP81128.1 - 3e-06 27.3 10.9 0.023 14.9 1.3 5.7 4 2 2 6 6 6 3 PPR repeat family AAA_22 PF13401.6 PRP81128.1 - 4.6e-06 27.0 0.0 2e-05 24.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP81128.1 - 0.0015 18.9 0.7 0.0049 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain PPR_3 PF13812.6 PRP81128.1 - 0.009 16.1 1.3 7.4 6.7 0.0 3.0 2 0 0 2 2 2 2 Pentatricopeptide repeat domain EAF PF09816.9 PRP81129.1 - 1.3e-15 57.6 0.1 1.3e-15 57.6 0.1 2.3 2 1 0 2 2 2 1 RNA polymerase II transcription elongation factor Cwf_Cwc_15 PF04889.12 PRP81129.1 - 0.011 15.6 7.4 0.016 15.0 7.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AF-4 PF05110.13 PRP81129.1 - 0.011 13.9 24.8 0.014 13.5 24.8 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 PRP81129.1 - 2.2 7.8 26.9 0.51 9.9 15.7 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-CHCC PF10276.9 PRP81130.1 - 2.3e-13 50.0 0.5 4.1e-13 49.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger domain MFS_1 PF07690.16 PRP81131.1 - 3.9e-40 137.8 38.5 5e-40 137.5 30.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PRP81131.1 - 8.7e-07 27.6 1.7 8.7e-07 27.6 1.7 3.4 2 2 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane_5 PF13346.6 PRP81131.1 - 0.011 15.3 8.5 0.011 15.3 8.5 3.0 3 1 1 4 4 4 0 ABC-2 family transporter protein Gly-zipper_Omp PF13488.6 PRP81131.1 - 0.022 14.7 1.2 0.022 14.7 1.2 3.0 2 1 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 PRP81131.1 - 0.063 13.0 0.4 0.063 13.0 0.4 3.1 3 1 0 3 3 3 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 PRP81131.1 - 0.11 12.4 14.6 0.72 9.8 2.6 2.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain tRNA-synt_2d PF01409.20 PRP81132.1 - 2.5e-87 292.4 0.0 3.3e-87 292.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 PRP81132.1 - 9.4e-15 54.7 0.3 9.4e-15 54.7 0.3 1.9 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 PRP81132.1 - 4.6e-06 26.2 0.0 0.0065 15.9 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 PRP81132.1 - 0.00026 20.2 0.0 0.001 18.2 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 PRP81132.1 - 0.0039 17.2 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 PRP81132.1 - 0.032 14.2 0.5 0.082 12.9 0.5 1.8 1 0 0 1 1 1 0 PheRS DNA binding domain 2 PS_Dcarbxylase PF02666.15 PRP81133.1 - 7.3e-60 202.0 0.0 9.9e-60 201.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 PRP81133.1 - 3.2e-19 69.1 0.1 1.6e-18 66.9 0.0 2.1 2 0 0 2 2 2 1 C2 domain EF-hand_1 PF00036.32 PRP81133.1 - 5.6e-10 38.1 0.0 0.00073 18.9 0.0 3.0 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PRP81133.1 - 3.6e-09 36.9 0.0 1.1e-08 35.4 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP81133.1 - 2.7e-08 33.1 0.1 0.015 15.1 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PRP81133.1 - 2.8e-06 27.1 0.0 0.0028 17.5 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP81133.1 - 0.0022 17.4 0.0 2.8 7.6 0.0 2.9 2 0 0 2 2 2 2 EF hand DUF3598 PF12204.8 PRP81134.1 - 0.054 13.0 0.5 0.066 12.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) DUF4746 PF15928.5 PRP81134.1 - 0.57 9.6 5.0 0.66 9.3 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pkinase_Tyr PF07714.17 PRP81135.1 - 9.1e-68 228.3 0.0 1.2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81135.1 - 5.3e-52 176.8 0.0 7.3e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP81135.1 - 5e-14 52.1 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 PRP81135.1 - 0.00023 20.2 0.1 0.0024 16.9 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PRP81135.1 - 0.00058 19.9 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cbl_N2 PF02761.14 PRP81135.1 - 0.009 16.7 0.0 0.022 15.4 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain ABC1 PF03109.16 PRP81135.1 - 0.026 14.7 0.0 0.076 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC1 family SMN PF06003.12 PRP81136.1 - 7.4 5.7 11.4 1.1 8.4 7.3 1.6 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) AAA PF00004.29 PRP81137.1 - 3.6e-44 150.4 0.1 1.5e-43 148.4 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP81137.1 - 2.3e-08 34.1 0.1 6.3e-08 32.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 PRP81137.1 - 4.1e-08 32.9 0.0 1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PRP81137.1 - 4.3e-07 30.5 0.2 4.2e-05 24.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 PRP81137.1 - 5.2e-07 29.5 0.4 1.2e-06 28.4 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 PRP81137.1 - 1.1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PRP81137.1 - 4.3e-05 23.8 0.4 0.0041 17.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 PRP81137.1 - 0.00012 21.3 0.0 0.00022 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 PRP81137.1 - 0.00048 19.9 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 PRP81137.1 - 0.00052 20.0 0.0 0.013 15.5 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PRP81137.1 - 0.00088 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 PRP81137.1 - 0.00088 18.6 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 PRP81137.1 - 0.00088 19.8 0.0 0.0024 18.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 PRP81137.1 - 0.00095 19.1 0.1 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_33 PF13671.6 PRP81137.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PRP81137.1 - 0.002 17.9 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 PRP81137.1 - 0.0023 18.3 0.0 0.0045 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.26 PRP81137.1 - 0.0024 17.6 0.1 0.11 12.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 PRP81137.1 - 0.0027 17.1 0.1 0.0061 16.0 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PRP81137.1 - 0.0064 16.4 0.1 0.03 14.2 0.0 2.1 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 PRP81137.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PRP81137.1 - 0.0074 15.8 0.1 0.046 13.2 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 PRP81137.1 - 0.0075 16.0 1.7 0.015 15.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 PRP81137.1 - 0.017 15.2 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PRP81137.1 - 0.018 14.8 0.6 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PRP81137.1 - 0.026 14.1 0.7 0.099 12.2 0.1 2.0 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 PRP81137.1 - 0.029 13.6 0.0 0.2 10.8 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Torsin PF06309.11 PRP81137.1 - 0.051 13.7 0.1 0.14 12.2 0.0 1.7 2 0 0 2 2 1 0 Torsin DUF3450 PF11932.8 PRP81137.1 - 0.057 12.7 0.8 0.1 11.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATPase PF06745.13 PRP81137.1 - 0.063 12.6 1.1 0.41 10.0 0.0 2.5 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 PRP81137.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 PRP81137.1 - 0.13 12.8 0.0 1.4 9.5 0.0 2.5 3 1 0 3 3 2 0 ABC transporter AAA_24 PF13479.6 PRP81137.1 - 0.31 10.7 1.6 0.34 10.6 0.1 2.0 2 1 0 2 2 1 0 AAA domain RabGAP-TBC PF00566.18 PRP81138.1 - 2.4e-47 161.4 0.3 5.4e-47 160.2 0.1 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Lipase_3 PF01764.25 PRP81139.1 - 1.7e-11 44.2 0.0 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) LETM1 PF07766.13 PRP81140.1 - 0.006 16.0 1.2 0.028 13.8 1.1 1.9 1 1 1 2 2 2 1 LETM1-like protein SAP PF02037.27 PRP81140.1 - 0.28 11.0 4.4 21 5.0 0.3 3.4 2 1 1 3 3 3 0 SAP domain Glyco_hydro_18 PF00704.28 PRP81142.1 - 1.5e-21 77.5 5.5 3.3e-21 76.3 5.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Cupin_8 PF13621.6 PRP81144.1 - 3.1e-24 86.1 0.4 5.5e-24 85.3 0.4 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PRP81144.1 - 7.6e-14 52.1 0.0 2.1e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 PRP81144.1 - 7e-06 25.7 0.1 1.1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein F-box-like PF12937.7 PRP81144.1 - 5e-05 23.1 0.9 0.00014 21.7 0.9 1.8 1 0 0 1 1 1 1 F-box-like Cupin_2 PF07883.11 PRP81144.1 - 0.012 15.3 0.0 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 Cupin domain CDC4_D PF16856.5 PRP81144.1 - 0.012 15.5 0.4 0.024 14.5 0.4 1.5 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain DUF569 PF04601.13 PRP81144.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF569) Cwf_Cwc_15 PF04889.12 PRP81144.1 - 0.13 12.0 1.1 0.2 11.4 1.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein VPS9 PF02204.18 PRP81145.1 - 3.5e-16 59.3 0.1 6.4e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Orbi_VP5 PF00901.17 PRP81145.1 - 0.0091 14.4 0.1 0.013 13.9 0.1 1.2 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP5 DcrB PF08786.11 PRP81146.1 - 0.011 15.8 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 0 DcrB DUF4094 PF13334.6 PRP81146.1 - 0.09 13.2 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Val_tRNA-synt_C PF10458.9 PRP81146.1 - 0.16 12.3 4.5 0.25 11.6 4.5 1.3 1 1 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Ank_2 PF12796.7 PRP81147.1 - 6.5e-30 103.6 0.5 1.2e-10 41.9 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81147.1 - 9.7e-16 57.9 0.5 0.00034 21.1 0.0 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP81147.1 - 8.1e-14 51.4 0.6 0.026 15.0 0.0 7.0 3 1 3 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PRP81147.1 - 4.5e-13 49.1 1.1 0.0075 16.6 0.1 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81147.1 - 4.1e-08 32.9 0.1 8.5 7.3 0.0 6.5 6 0 0 6 6 6 2 Ankyrin repeat VWA_3_C PF18571.1 PRP81147.1 - 0.0096 15.8 1.7 15 5.5 0.0 5.2 6 0 0 6 6 6 1 von Willebrand factor type A C-terminal domain Adaptin_N PF01602.20 PRP81147.1 - 0.022 13.3 0.6 2.8 6.4 0.4 2.2 2 0 0 2 2 2 0 Adaptin N terminal region DUF5309 PF17236.2 PRP81147.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5309) HTH_37 PF13744.6 PRP81147.1 - 0.13 12.3 0.1 0.39 10.7 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain V-ATPase_H_C PF11698.8 PRP81147.1 - 0.13 12.4 0.0 0.72 10.0 0.0 2.3 2 0 0 2 2 2 0 V-ATPase subunit H DUF3387 PF11867.8 PRP81147.1 - 0.23 10.8 1.6 0.24 10.7 0.0 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3387) BTB_2 PF02214.22 PRP81148.1 - 4.8e-18 65.3 0.0 1.4e-17 63.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain TLD PF07534.16 PRP81148.1 - 1.4e-13 51.2 0.0 5.9e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 TLD BTB_3 PF16017.5 PRP81148.1 - 0.0085 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Wap1 PF16997.5 PRP81148.1 - 0.022 14.0 0.4 0.036 13.2 0.4 1.2 1 0 0 1 1 1 0 Wap1 domain FliD_N PF02465.18 PRP81148.1 - 0.33 11.7 3.2 0.21 12.3 0.9 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus WD40 PF00400.32 PRP81149.1 - 5.1e-06 27.1 25.5 0.26 12.2 0.1 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP81149.1 - 7.5e-05 22.9 0.3 0.97 9.8 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP81149.1 - 0.089 12.1 0.1 0.39 10.0 0.0 2.1 2 1 0 2 2 2 0 WD40-like domain Chorismate_bind PF00425.18 PRP81151.1 - 8.6e-87 290.9 0.0 1.3e-86 290.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Aminotran_4 PF01063.19 PRP81151.1 - 1.1e-30 107.2 0.0 2e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV GATase PF00117.28 PRP81151.1 - 1.1e-30 106.8 0.0 1.8e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HMG_box PF00505.19 PRP81151.1 - 7.1e-18 64.8 4.2 2.5e-17 63.0 4.2 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box Anth_synt_I_N PF04715.13 PRP81151.1 - 2.3e-15 57.1 0.0 1.3e-14 54.6 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region HMG_box_2 PF09011.10 PRP81151.1 - 1.2e-13 51.5 3.9 3e-13 50.1 3.9 1.7 1 0 0 1 1 1 1 HMG-box domain Peptidase_C26 PF07722.13 PRP81151.1 - 4.8e-05 23.2 0.2 0.0021 17.9 0.2 2.2 1 1 0 1 1 1 1 Peptidase C26 GP46 PF07409.12 PRP81154.1 - 0.022 14.5 0.1 1.6 8.5 0.0 3.4 4 0 0 4 4 4 0 Phage protein GP46 Ank_4 PF13637.6 PRP81154.1 - 0.072 13.7 0.1 8.1 7.2 0.0 4.1 4 1 0 4 4 4 0 Ankyrin repeats (many copies) Aldose_epim PF01263.20 PRP81155.1 - 2e-39 135.7 0.4 2.5e-39 135.4 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase zf-Di19 PF05605.12 PRP81156.1 - 8.5e-08 32.4 13.4 6.7e-07 29.5 3.7 3.4 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-RING_2 PF13639.6 PRP81156.1 - 3.3e-07 30.5 29.8 5.9e-07 29.7 11.7 4.0 3 1 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 PRP81156.1 - 0.00018 21.1 6.4 0.00018 21.1 6.4 3.1 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PRP81156.1 - 0.0013 18.6 21.0 0.0049 16.7 11.1 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_9 PF16293.5 PRP81156.1 - 0.012 15.5 3.5 7.3 6.5 0.1 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Rubredoxin PF00301.20 PRP81156.1 - 0.013 15.5 2.3 4.5 7.4 0.1 3.5 3 0 0 3 3 3 0 Rubredoxin zf-RING_UBOX PF13445.6 PRP81156.1 - 0.023 14.7 9.4 0.023 14.7 9.4 3.5 3 0 0 3 3 3 0 RING-type zinc-finger zf-C2H2_4 PF13894.6 PRP81156.1 - 0.11 13.4 22.1 0.23 12.4 0.1 5.1 4 1 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.15 PRP81156.1 - 0.12 12.4 5.4 0.66 10.0 1.2 3.0 3 0 0 3 3 2 0 BED zinc finger zf-C3HC4 PF00097.25 PRP81156.1 - 0.22 11.4 22.7 0.086 12.7 11.4 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Cwf_Cwc_15 PF04889.12 PRP81156.1 - 0.61 9.8 6.1 0.98 9.1 6.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-rbx1 PF12678.7 PRP81156.1 - 0.62 10.4 24.4 0.16 12.3 13.1 4.1 4 1 0 4 4 4 0 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 PRP81156.1 - 0.98 9.7 8.0 9.2 6.6 0.3 3.8 3 0 0 3 3 3 0 zinc-ribbon zf-WRNIP1_ubi PF18279.1 PRP81156.1 - 1 10.1 6.5 12 6.8 0.1 3.7 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_5 PF14634.6 PRP81156.1 - 2.2 8.3 27.4 0.21 11.6 11.1 4.0 3 1 1 4 4 4 0 zinc-RING finger domain BRCT PF00533.26 PRP81157.1 - 4.9e-12 46.1 0.1 1.4e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PRP81157.1 - 5.5e-09 35.9 0.2 1.1e-08 34.9 0.2 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 PRP81157.1 - 2.9e-06 27.6 0.3 7.3e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 PRP81157.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain RasGAP PF00616.19 PRP81158.1 - 1.9e-11 44.1 0.1 4.1e-05 23.4 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase LRR_6 PF13516.6 PRP81158.1 - 5.4e-08 32.3 19.9 0.0036 17.2 0.9 7.8 8 0 0 8 8 8 3 Leucine Rich repeat Vma12 PF11712.8 PRP81158.1 - 0.15 12.1 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Alpha-amylase PF00128.24 PRP81159.1 - 2.2e-50 172.1 1.2 4.6e-50 171.1 1.2 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL10 PF02638.15 PRP81159.1 - 0.00034 19.8 0.3 0.0006 19.0 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 DUF1966 PF09260.11 PRP81159.1 - 0.0015 18.8 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Cellulase-like PF12876.7 PRP81159.1 - 0.0054 16.1 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Sugar-binding cellulase-like NDUF_B12 PF08122.12 PRP81159.1 - 3.3 7.8 7.5 5.9 7.0 3.1 2.7 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family MRNIP PF15749.5 PRP81160.1 - 0.37 11.5 5.0 0.18 12.5 1.1 2.4 2 1 1 3 3 3 0 MRN-interacting protein CRT-like PF08627.10 PRP81161.1 - 2.6e-35 122.0 8.1 1.8e-33 115.9 8.0 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 PRP81161.1 - 1.1e-08 34.7 9.4 2.4e-08 33.5 7.6 2.2 1 1 1 2 2 2 1 UAA transporter family SLC35F PF06027.12 PRP81161.1 - 0.00011 21.8 11.7 0.00043 19.9 4.8 2.3 2 0 0 2 2 2 2 Solute carrier family 35 EamA PF00892.20 PRP81161.1 - 0.00045 20.4 4.9 0.00045 20.4 4.9 4.1 4 0 0 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.15 PRP81161.1 - 0.042 13.0 5.9 0.058 12.6 4.5 1.9 2 1 0 2 2 2 0 Nucleotide-sugar transporter VirB8 PF04335.13 PRP81161.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 VirB8 protein DUF872 PF05915.12 PRP81161.1 - 0.13 12.5 1.6 0.45 10.7 0.8 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF2339 PF10101.9 PRP81161.1 - 0.26 9.8 15.5 8.2 4.9 15.3 2.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF4191 PF13829.6 PRP81161.1 - 7 5.9 9.4 0.81 9.0 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) Alpha-amylase PF00128.24 PRP81162.1 - 6.8e-50 170.5 0.3 1.2e-49 169.7 0.3 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain GHL10 PF02638.15 PRP81162.1 - 0.014 14.5 0.5 0.023 13.8 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase-like 10 Alpha-amylase PF00128.24 PRP81163.1 - 4.1e-50 171.2 0.8 9.6e-50 170.0 0.8 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL10 PF02638.15 PRP81163.1 - 0.014 14.5 0.1 0.027 13.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Cellulase-like PF12876.7 PRP81163.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF1966 PF09260.11 PRP81163.1 - 0.14 12.5 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) Polysacc_lyase PF14099.6 PRP81164.1 - 4.3e-07 30.0 0.8 8.4e-07 29.0 0.8 1.4 1 1 0 1 1 1 1 Polysaccharide lyase C2 PF00168.30 PRP81165.1 - 2e-08 34.4 0.1 2e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 C2 domain V-SNARE_C PF12352.8 PRP81165.1 - 0.054 13.8 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus EGF_2 PF07974.13 PRP81166.1 - 0.17 12.3 9.7 0.33 11.4 9.7 1.5 1 0 0 1 1 1 0 EGF-like domain DUF3989 PF13150.6 PRP81166.1 - 0.3 10.8 0.9 1.3 8.8 0.9 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) PCRF PF03462.18 PRP81167.1 - 2e-47 161.6 0.1 4e-47 160.6 0.1 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 PRP81167.1 - 1.3e-34 118.6 0.6 1.3e-34 118.6 0.6 2.2 2 1 1 3 3 3 1 RF-1 domain TCTP PF00838.17 PRP81167.1 - 0.04 14.2 0.4 0.081 13.3 0.4 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein THF_DHG_CYH PF00763.23 PRP81168.1 - 0.089 13.1 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF4010 PF13194.6 PRP81168.1 - 0.22 11.2 17.5 0.12 12.0 3.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4010) GAPT PF11770.8 PRP81168.1 - 0.43 10.4 3.4 32 4.4 0.0 3.5 3 0 0 3 3 3 0 GRB2-binding adapter (GAPT) Coq4 PF05019.13 PRP81168.1 - 0.45 9.8 2.6 0.79 9.0 0.2 2.4 3 0 0 3 3 3 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 FixS PF03597.15 PRP81168.1 - 0.57 9.9 0.0 0.57 9.9 0.0 4.2 4 0 0 4 4 4 0 Cytochrome oxidase maturation protein cbb3-type DUF4307 PF14155.6 PRP81168.1 - 7.7 6.4 7.4 8.7 6.2 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4307) Voltage_CLC PF00654.20 PRP81169.1 - 1.9e-62 211.6 33.4 1.9e-62 211.6 33.4 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PRP81169.1 - 5.6e-07 29.9 1.6 0.0094 16.4 0.5 2.5 2 0 0 2 2 2 2 CBS domain C2 PF00168.30 PRP81170.1 - 5.4e-22 78.0 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 PRP81170.1 - 0.0024 17.4 0.0 0.01 15.3 0.0 2.0 2 0 0 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain DUF5091 PF17012.5 PRP81170.1 - 0.058 13.6 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5091) UQ_con PF00179.26 PRP81171.1 - 1.5e-33 115.4 0.0 7.8e-32 109.8 0.0 2.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_hydro_16 PF00722.21 PRP81173.1 - 3.2e-27 95.1 3.4 7.1e-27 94.0 2.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 PRP81173.1 - 2.7e-12 45.9 4.6 3.5e-08 32.3 1.0 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Carb_bind PF10645.9 PRP81173.1 - 0.00057 20.1 37.9 0.0069 16.6 14.3 4.5 2 2 2 4 4 4 3 Carbohydrate binding BTB PF00651.31 PRP81174.1 - 6.7e-17 61.7 0.2 3.4e-08 33.7 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 PRP81174.1 - 2.6e-15 55.8 9.8 4e-07 29.7 0.2 5.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 PRP81174.1 - 1e-13 51.6 9.2 4.5e-05 24.0 0.0 6.3 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat LRR_8 PF13855.6 PRP81174.1 - 0.0012 18.6 1.1 0.0029 17.3 1.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PRP81174.1 - 0.0012 19.2 1.3 0.0067 16.8 1.2 2.3 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) Wzt_C PF14524.6 PRP81174.1 - 0.0052 16.8 0.0 0.085 12.9 0.0 2.9 2 1 0 2 2 2 1 Wzt C-terminal domain Filamin PF00630.19 PRP81174.1 - 0.0058 17.4 0.0 0.018 15.9 0.0 1.9 1 0 0 1 1 1 1 Filamin/ABP280 repeat Cullin_binding PF03556.15 PRP81175.1 - 3.5e-17 63.0 0.3 5.2e-17 62.4 0.3 1.3 1 0 0 1 1 1 1 Cullin binding SKIP_SNW PF02731.15 PRP81176.1 - 1.2e-61 207.1 2.0 1.2e-61 207.1 2.0 2.3 2 0 0 2 2 2 1 SKIP/SNW domain FGGY_C PF02782.16 PRP81178.1 - 7.6e-38 130.2 0.1 1.5e-37 129.3 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 PRP81178.1 - 9.1e-33 113.8 0.1 7.3e-26 91.2 0.1 4.0 2 1 1 3 3 3 2 FGGY family of carbohydrate kinases, N-terminal domain Cyclin_N PF00134.23 PRP81178.1 - 5.9e-11 42.2 0.2 1.2e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 PRP81178.1 - 1.7e-05 25.3 0.1 3.6e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin MACPF PF01823.19 PRP81178.1 - 0.0012 19.0 0.2 0.0027 17.8 0.2 1.5 1 0 0 1 1 1 1 MAC/Perforin domain T4-Gluco-transf PF09198.10 PRP81178.1 - 0.012 15.2 0.6 0.03 13.9 0.6 1.7 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase WH1 PF00568.23 PRP81179.1 - 1.8e-21 76.2 0.0 2.6e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 PRP81179.1 - 2.7e-10 39.6 2.1 3.9e-10 39.1 2.1 1.2 1 0 0 1 1 1 1 VASP tetramerisation domain WH2 PF02205.20 PRP81179.1 - 5.8e-09 35.5 0.3 1.6e-08 34.1 0.3 1.8 1 0 0 1 1 1 1 WH2 motif Ank_2 PF12796.7 PRP81181.1 - 3.5e-50 168.5 2.4 5.4e-10 39.7 0.0 6.1 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81181.1 - 6.2e-28 96.8 5.6 8.1e-06 26.3 0.0 7.2 4 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP81181.1 - 1.8e-16 60.0 7.8 0.0036 17.6 0.1 9.1 4 3 5 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP81181.1 - 7.9e-15 54.6 8.2 0.12 12.9 0.0 9.6 8 3 2 10 10 10 5 Ankyrin repeat Ank_3 PF13606.6 PRP81181.1 - 9.3e-15 53.3 3.1 2.1 9.2 0.0 10.0 12 0 0 12 12 12 3 Ankyrin repeat PRODH PF18327.1 PRP81181.1 - 0.11 12.8 2.0 2.6 8.3 0.1 3.9 4 0 0 4 4 4 0 Proline utilization A proline dehydrogenase N-terminal domain Zn_clus PF00172.18 PRP81183.1 - 1.7e-09 37.6 10.8 4e-09 36.5 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 PRP81183.1 - 2.6e-07 29.9 0.1 4.8e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactamase_B PF00753.27 PRP81184.1 - 2.3e-17 63.7 0.2 3.2e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PRP81184.1 - 0.00062 19.3 0.2 0.001 18.6 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Cyc-maltodext_C PF10438.9 PRP81186.1 - 0.045 13.8 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain ICE2 PF08426.10 PRP81187.1 - 0.11 11.6 1.2 0.11 11.6 1.2 1.0 1 0 0 1 1 1 0 ICE2 FMN_red PF03358.15 PRP81188.1 - 1.7e-27 96.1 0.0 2.3e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 PRP81188.1 - 5.8e-05 22.9 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold TLD PF07534.16 PRP81189.1 - 4.1e-23 82.1 0.1 3.3e-13 50.0 0.0 2.7 2 0 0 2 2 2 2 TLD BTB_2 PF02214.22 PRP81189.1 - 1.9e-17 63.4 0.0 4.1e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPA PF08616.10 PRP81189.1 - 2.3e-06 27.6 0.0 5.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 PRP81189.1 - 0.00014 20.7 0.1 0.00039 19.2 0.2 1.8 1 1 0 1 1 1 1 Transport protein Avl9 DUF3500 PF12006.8 PRP81189.1 - 0.065 12.7 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) 4HBT PF03061.22 PRP81190.1 - 1.1e-10 41.7 0.0 1.2e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Neurensin PF14927.6 PRP81191.1 - 0.017 14.8 0.6 0.67 9.7 0.1 2.3 2 0 0 2 2 2 0 Neurensin Shisa PF13908.6 PRP81191.1 - 0.046 14.0 0.9 0.078 13.2 0.9 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Sulf_transp PF04143.14 PRP81192.1 - 1.6e-34 119.9 33.9 1.6e-34 119.9 33.9 2.6 1 1 1 2 2 2 1 Sulphur transport DUF599 PF04654.12 PRP81193.1 - 2.5e-25 89.1 3.4 6.8e-24 84.5 3.4 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF599 Thioredoxin PF00085.20 PRP81194.1 - 1.4e-59 198.4 0.2 3.3e-30 104.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Ras PF00071.22 PRP81194.1 - 2.6e-24 85.6 0.5 8e-22 77.6 0.1 2.5 2 0 0 2 2 2 1 Ras family Thioredoxin_6 PF13848.6 PRP81194.1 - 5.9e-24 85.0 0.2 2.6e-20 73.1 0.1 3.3 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PRP81194.1 - 2.7e-09 37.1 1.6 0.007 16.5 0.0 4.2 4 1 0 4 4 4 2 Thioredoxin-like Roc PF08477.13 PRP81194.1 - 4.9e-09 36.5 0.2 0.00062 20.0 0.0 3.6 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase OST3_OST6 PF04756.13 PRP81194.1 - 1.8e-07 30.8 0.1 0.0061 16.0 0.0 2.6 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PRP81194.1 - 2.2e-07 31.1 0.0 0.0067 16.7 0.0 3.9 2 1 1 3 3 3 2 Thioredoxin-like F-box-like PF12937.7 PRP81194.1 - 5.8e-07 29.3 1.6 1.6e-06 27.9 1.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP81194.1 - 1.6e-06 27.9 0.8 5.6e-06 26.1 0.8 2.1 1 0 0 1 1 1 1 F-box domain Thioredoxin_2 PF13098.6 PRP81194.1 - 5.5e-06 26.8 0.6 0.005 17.3 0.1 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 PRP81194.1 - 0.00013 21.9 0.0 0.64 9.9 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 PRP81194.1 - 0.00062 19.5 2.6 1.1 8.9 0.0 3.3 3 0 0 3 3 3 2 Redoxin F-box_4 PF15966.5 PRP81194.1 - 0.00093 19.1 0.2 0.0022 17.8 0.2 1.6 1 0 0 1 1 1 1 F-box ERp29_N PF07912.13 PRP81194.1 - 0.0024 18.0 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 1 ERp29, N-terminal domain Ploopntkinase2 PF18747.1 PRP81194.1 - 0.023 14.0 0.0 0.072 12.3 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase2 Calsequestrin PF01216.17 PRP81194.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Calsequestrin AAA_16 PF13191.6 PRP81194.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TraF PF13728.6 PRP81194.1 - 0.092 12.6 0.0 1.3 8.8 0.0 2.5 2 1 0 2 2 2 0 F plasmid transfer operon protein AAA_28 PF13521.6 PRP81194.1 - 0.093 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1279 PF06916.13 PRP81195.1 - 1.9e-14 54.0 1.2 2.3e-14 53.7 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) MatE PF01554.18 PRP81195.1 - 0.052 13.2 0.7 0.052 13.2 0.7 2.0 1 1 0 1 1 1 0 MatE Syndecan PF01034.20 PRP81196.1 - 0.015 15.2 2.0 0.038 13.9 0.1 2.3 2 0 0 2 2 2 0 Syndecan domain DUF5058 PF16481.5 PRP81196.1 - 0.09 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) MFS_2 PF13347.6 PRP81196.1 - 0.13 10.8 0.3 0.17 10.4 0.3 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein NADH-G_4Fe-4S_3 PF10588.9 PRP81196.1 - 0.26 10.9 4.5 0.68 9.5 1.3 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Alba PF01918.21 PRP81197.1 - 4.2e-21 74.5 0.1 6.3e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 PRP81197.1 - 1.3e-06 28.4 0.6 1.8e-06 28.0 0.6 1.5 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P LRR_8 PF13855.6 PRP81198.1 - 2.6e-08 33.5 19.4 0.00028 20.6 0.2 7.0 5 2 1 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 PRP81198.1 - 4.5e-05 23.7 22.6 0.0068 16.8 0.9 7.2 3 1 7 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP81198.1 - 0.00011 22.3 11.2 26 5.9 0.0 8.6 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP81198.1 - 0.0015 18.4 29.4 3 8.1 0.2 9.4 10 0 0 10 10 10 4 Leucine Rich repeat TLD PF07534.16 PRP81199.1 - 6.6e-19 68.5 0.1 1.2e-18 67.7 0.1 1.5 1 0 0 1 1 1 1 TLD BTB_2 PF02214.22 PRP81199.1 - 8.5e-18 64.5 0.0 2.1e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ank_2 PF12796.7 PRP81199.1 - 0.00021 21.8 0.0 1.7 9.2 0.0 3.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) BTB_3 PF16017.5 PRP81199.1 - 0.00022 21.3 0.0 0.00054 20.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.6 PRP81199.1 - 0.0031 18.0 0.2 1.2 9.8 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP81199.1 - 0.026 14.9 0.0 13 6.2 0.0 4.5 4 2 2 6 6 6 0 Ankyrin repeats (many copies) GIDA_assoc PF13932.6 PRP81199.1 - 0.18 12.0 1.3 0.42 10.8 1.3 1.6 1 1 0 1 1 1 0 GidA associated domain BTB_2 PF02214.22 PRP81201.1 - 4.1e-50 168.1 0.0 5.6e-16 58.7 0.0 3.5 3 0 0 3 3 3 3 BTB/POZ domain TLD PF07534.16 PRP81201.1 - 4e-34 117.8 9.6 3.1e-17 63.1 0.0 5.1 3 2 0 3 3 3 3 TLD BTB_3 PF16017.5 PRP81201.1 - 5.6e-08 32.8 0.0 0.1 12.7 0.0 3.4 3 0 0 3 3 3 3 BTB/POZ domain YaeQ PF07152.12 PRP81201.1 - 0.096 12.3 0.6 8.6 5.9 0.0 2.8 3 0 0 3 3 3 0 YaeQ protein E2F_CC-MB PF16421.5 PRP81201.1 - 0.53 10.7 2.7 68 3.9 0.5 3.7 4 0 0 4 4 4 0 E2F transcription factor CC-MB domain Mod_r PF07200.13 PRP81201.1 - 0.79 9.8 15.6 4.5 7.4 1.8 3.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FliD_N PF02465.18 PRP81201.1 - 0.97 10.2 7.6 5.6 7.7 0.2 3.9 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus DUF1993 PF09351.10 PRP81201.1 - 1.8 8.7 5.1 1.2 9.3 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) YfcL PF08891.11 PRP81201.1 - 1.9 8.9 3.6 42 4.6 0.5 3.1 2 0 0 2 2 2 0 YfcL protein TLD PF07534.16 PRP81202.1 - 2.1e-33 115.5 9.1 2.8e-14 53.5 0.5 3.9 4 0 0 4 4 3 3 TLD BTB_2 PF02214.22 PRP81202.1 - 2.7e-19 69.3 0.7 1.3e-16 60.8 0.1 3.2 2 0 0 2 2 2 1 BTB/POZ domain OmpH PF03938.14 PRP81202.1 - 0.00046 20.5 21.7 0.00076 19.8 6.3 2.4 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF3552 PF12072.8 PRP81202.1 - 0.00069 19.1 11.6 0.00069 19.1 11.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) Laminin_II PF06009.12 PRP81202.1 - 0.016 15.2 15.2 0.031 14.3 2.5 2.4 2 0 0 2 2 2 0 Laminin Domain II Fez1 PF06818.15 PRP81202.1 - 0.022 15.2 18.3 0.055 13.9 6.9 2.4 2 0 0 2 2 2 0 Fez1 AI-2E_transport PF01594.16 PRP81202.1 - 0.032 13.4 0.8 0.11 11.6 0.1 1.9 2 0 0 2 2 2 0 AI-2E family transporter Syntaxin_2 PF14523.6 PRP81202.1 - 0.066 13.6 10.8 0.38 11.1 2.4 2.7 2 0 0 2 2 2 0 Syntaxin-like protein Mod_r PF07200.13 PRP81202.1 - 0.073 13.2 27.1 0.3 11.2 9.9 2.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 PRP81202.1 - 0.08 13.0 21.2 0.17 12.0 7.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 PRP81202.1 - 0.086 13.3 20.3 1.6 9.2 10.3 2.7 2 0 0 2 2 2 0 AAA domain Jnk-SapK_ap_N PF09744.9 PRP81202.1 - 0.087 13.0 27.0 0.56 10.4 11.9 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 EzrA PF06160.12 PRP81202.1 - 0.14 10.3 22.7 0.0052 15.0 6.8 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.9 PRP81202.1 - 0.26 11.6 18.3 0.044 14.1 6.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 PRP81202.1 - 0.37 10.3 12.6 1.6 8.2 4.0 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 PRP81202.1 - 0.53 9.3 19.1 0.014 14.5 6.3 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 PRP81202.1 - 0.67 10.5 27.1 0.57 10.7 10.9 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF16 PF01519.16 PRP81202.1 - 0.86 10.1 11.8 5.9 7.4 2.5 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 HrpB7 PF09486.10 PRP81202.1 - 0.91 9.9 6.8 0.85 10.0 0.6 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FapA PF03961.13 PRP81202.1 - 1.3 7.6 17.6 2.8 6.4 6.8 2.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A Sec34 PF04136.15 PRP81202.1 - 1.4 8.7 13.8 0.64 9.9 2.3 2.7 2 0 0 2 2 2 0 Sec34-like family YlqD PF11068.8 PRP81202.1 - 1.7 9.0 15.2 2.8 8.3 3.9 2.7 2 0 0 2 2 2 0 YlqD protein Tropomyosin_1 PF12718.7 PRP81202.1 - 1.9 8.7 30.5 2.1 8.5 12.4 2.4 2 0 0 2 2 2 0 Tropomyosin like EMP24_GP25L PF01105.24 PRP81202.1 - 2.2 8.2 12.3 4.5 7.2 1.3 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Spc7 PF08317.11 PRP81202.1 - 3.3 6.5 24.5 2.6 6.8 11.1 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 PRP81202.1 - 3.9 7.6 12.8 7 6.8 2.8 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1910 PF08928.10 PRP81202.1 - 4.3 7.4 7.2 0.66 10.0 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) UPF0449 PF15136.6 PRP81202.1 - 4.5 7.8 24.2 1 9.8 5.3 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF724 PF05266.14 PRP81202.1 - 4.7 7.0 21.4 4 7.2 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TBCC_N PF16752.5 PRP81202.1 - 5.4 7.5 21.5 1.9 8.9 8.6 2.9 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Allexi_40kDa PF05549.11 PRP81202.1 - 5.7 6.4 9.1 7.2 6.0 1.9 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein FAM76 PF16046.5 PRP81202.1 - 6 6.1 11.3 1.5 8.1 2.1 2.2 2 0 0 2 2 2 0 FAM76 protein PDDEXK_6 PF04720.12 PRP81202.1 - 6.4 6.7 12.9 1.2 9.1 3.4 2.5 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Cauli_AT PF03233.13 PRP81202.1 - 6.5 6.6 12.8 12 5.8 3.7 2.5 2 0 0 2 2 2 0 Aphid transmission protein ATG16 PF08614.11 PRP81202.1 - 6.6 6.9 22.4 0.22 11.7 9.2 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 PRP81202.1 - 7.9 4.2 15.5 1.9 6.3 3.9 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FliD_N PF02465.18 PRP81202.1 - 8.9 7.1 16.1 3.6 8.4 3.5 3.5 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Nefa_Nip30_N PF10187.9 PRP81203.1 - 2.9e-08 34.0 8.6 2.9e-08 34.0 8.6 2.0 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 PRP81203.1 - 6.2e-05 22.8 9.6 8.8e-05 22.3 9.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) MMR_HSR1 PF01926.23 PRP81204.1 - 8.1e-49 164.5 5.1 3.9e-25 88.2 0.3 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP81204.1 - 1.8e-27 95.8 1.4 1e-13 51.1 0.2 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 PRP81204.1 - 2.3e-24 85.5 0.5 5.8e-24 84.2 0.2 1.9 2 0 0 2 2 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 PRP81204.1 - 5.3e-20 71.8 7.5 5.7e-11 42.3 1.6 4.8 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 PRP81204.1 - 1.2e-19 70.5 6.4 2.1e-10 40.3 0.3 2.3 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 PRP81204.1 - 2.1e-10 40.7 8.8 0.013 15.4 0.1 4.3 3 1 1 4 4 4 3 RsgA GTPase Dynamin_N PF00350.23 PRP81204.1 - 2.4e-09 37.5 8.1 0.039 14.0 0.1 4.7 3 1 1 4 4 4 4 Dynamin family Ras PF00071.22 PRP81204.1 - 6.6e-07 29.1 2.7 0.017 14.7 0.1 4.3 3 2 1 4 4 4 2 Ras family Roc PF08477.13 PRP81204.1 - 8.2e-07 29.3 4.6 0.14 12.4 0.2 4.0 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP81204.1 - 1.1e-06 28.2 1.3 0.01 15.3 0.2 2.7 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA PF00004.29 PRP81204.1 - 1.5e-05 25.4 0.2 0.087 13.3 0.0 2.8 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PRP81204.1 - 8.2e-05 23.1 0.7 0.46 11.0 0.0 2.8 3 0 0 3 3 3 2 ABC transporter AAA_22 PF13401.6 PRP81204.1 - 0.00011 22.5 0.6 0.96 9.7 0.0 3.7 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 PRP81204.1 - 0.00013 22.4 0.1 0.61 10.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase NOG1 PF06858.14 PRP81204.1 - 0.00024 20.8 2.7 0.038 13.8 0.1 2.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1_Xtn PF16897.5 PRP81204.1 - 0.00031 20.7 0.8 0.97 9.5 0.0 3.3 3 0 0 3 3 3 2 C-terminal region of MMR_HSR1 domain TniB PF05621.11 PRP81204.1 - 0.00042 19.8 0.3 0.88 9.0 0.0 3.1 2 1 0 2 2 2 2 Bacterial TniB protein Guanylate_kin PF00625.21 PRP81204.1 - 0.00046 19.9 0.6 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 Guanylate kinase ATP-synt_ab PF00006.25 PRP81204.1 - 0.0013 18.4 0.5 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.6 PRP81204.1 - 0.0014 19.0 0.0 0.59 10.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 PRP81204.1 - 0.0026 17.7 0.1 2.2 8.1 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea NB-ARC PF00931.22 PRP81204.1 - 0.003 16.8 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 PRP81204.1 - 0.0036 17.1 0.1 0.96 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 PRP81204.1 - 0.0041 17.1 0.2 3.8 7.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 PRP81204.1 - 0.0075 15.8 0.5 0.41 10.0 0.0 2.9 2 1 1 3 3 3 1 Chromatin associated protein KTI12 MobB PF03205.14 PRP81204.1 - 0.011 15.6 1.1 0.88 9.5 0.1 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 PRP81204.1 - 0.013 15.4 2.0 1.7 8.6 0.2 2.6 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 PRP81204.1 - 0.021 14.7 0.0 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 cobW PF02492.19 PRP81204.1 - 0.025 14.2 7.6 1.9 8.0 0.1 3.7 2 2 2 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 PRP81204.1 - 0.034 13.9 0.0 5.5 6.8 0.0 3.0 3 0 0 3 3 2 0 P-loop containing region of AAA domain Septin PF00735.18 PRP81204.1 - 0.28 10.4 3.5 3 7.0 0.1 3.3 2 2 1 3 3 3 0 Septin Ligase_CoA PF00549.19 PRP81204.1 - 0.49 10.2 4.2 41 4.0 0.2 3.9 3 1 1 4 4 4 0 CoA-ligase DUF2306 PF10067.9 PRP81206.1 - 2.5e-14 53.7 9.9 2.5e-14 53.7 9.9 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF2306 PF10067.9 PRP81207.1 - 9.1e-14 51.9 13.5 9.1e-14 51.9 13.5 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 PRP81207.1 - 0.4 11.0 7.3 0.067 13.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF420) BTB_2 PF02214.22 PRP81208.1 - 4.2e-18 65.5 0.0 8.5e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 PRP81208.1 - 0.0087 16.2 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain MEKHLA PF08670.11 PRP81208.1 - 0.071 13.0 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 MEKHLA domain AAA PF00004.29 PRP81210.1 - 2.7e-42 144.3 0.0 6.3e-42 143.1 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP81210.1 - 7.9e-13 48.0 0.1 1.6e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PRP81210.1 - 9.9e-08 31.8 0.6 2.3e-07 30.7 0.6 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 PRP81210.1 - 3e-06 27.5 0.0 7.4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PRP81210.1 - 8.7e-06 25.8 0.0 4.6e-05 23.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP81210.1 - 2.3e-05 24.8 0.1 0.00042 20.7 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PRP81210.1 - 6.7e-05 23.2 1.3 0.0076 16.5 0.1 2.6 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 PRP81210.1 - 0.0004 20.2 0.0 0.00099 18.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PRP81210.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP81210.1 - 0.0013 19.2 0.3 0.014 16.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 PRP81210.1 - 0.0025 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 PRP81210.1 - 0.0052 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_28 PF13521.6 PRP81210.1 - 0.0093 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PRP81210.1 - 0.013 14.9 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 PRP81210.1 - 0.014 14.9 0.0 0.09 12.2 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein RILP PF11461.8 PRP81210.1 - 0.014 15.6 1.0 0.029 14.6 1.0 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein RNA_helicase PF00910.22 PRP81210.1 - 0.016 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 PRP81210.1 - 0.031 14.2 0.0 0.087 12.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 PRP81210.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 PRP81210.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PRP81210.1 - 0.048 14.2 0.2 1.2 9.7 0.0 2.6 3 0 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 PRP81210.1 - 0.053 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PRP81210.1 - 0.059 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HR1 PF02185.16 PRP81210.1 - 0.083 13.0 3.3 0.21 11.7 3.3 1.6 1 0 0 1 1 1 0 Hr1 repeat ATPase PF06745.13 PRP81210.1 - 0.083 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 KaiC Parvo_NS1 PF01057.17 PRP81210.1 - 0.098 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 PRP81210.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF4383 PF14325.6 PRP81211.1 - 0.0012 19.1 0.4 0.0018 18.5 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) SLC35F PF06027.12 PRP81212.1 - 1.1e-65 222.1 26.4 7.5e-29 101.2 4.6 3.0 2 1 1 3 3 3 3 Solute carrier family 35 EamA PF00892.20 PRP81212.1 - 5.5e-09 36.3 29.9 1.5e-05 25.1 1.5 3.9 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 PRP81212.1 - 1.3e-05 24.6 19.5 5e-05 22.6 19.4 1.8 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 PRP81212.1 - 0.56 9.5 19.4 3.7 6.8 18.6 2.3 1 1 0 1 1 1 0 Triose-phosphate Transporter family BAG PF02179.16 PRP81213.1 - 1e-07 32.3 0.3 1e-07 32.3 0.3 3.3 2 1 0 2 2 2 1 BAG domain Gly_acyl_tr_N PF06021.11 PRP81213.1 - 2.7 8.1 11.7 7.4 6.6 11.7 1.8 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Sulf_transp PF04143.14 PRP81215.1 - 2.7e-31 109.3 37.6 2.7e-31 109.3 37.6 2.7 1 1 1 2 2 2 1 Sulphur transport Sporozoite_P67 PF05642.11 PRP81216.1 - 1.1 7.2 3.5 1.6 6.8 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen VPS38 PF17649.1 PRP81216.1 - 5.7 5.7 13.3 0.1 11.5 2.5 2.6 2 1 1 3 3 3 0 Vacuolar protein sorting 38 Ank_2 PF12796.7 PRP81217.1 - 1.3e-15 57.7 0.0 8.4e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81217.1 - 6.1e-15 55.4 0.0 2.4e-11 43.9 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81217.1 - 3.3e-13 48.5 0.0 6.3e-07 29.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP81217.1 - 1.8e-12 47.2 0.0 4.8e-06 26.7 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP81217.1 - 4.5e-12 45.8 0.0 7.1e-08 32.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeat UFD1 PF03152.14 PRP81218.1 - 1.9e-35 121.9 0.1 7.6e-19 67.8 0.0 2.2 1 1 1 2 2 2 2 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 PRP81218.1 - 0.00032 20.4 0.1 0.00064 19.5 0.1 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RhoGEF PF00621.20 PRP81219.1 - 5.6e-40 137.5 1.2 5.6e-40 137.5 1.2 1.7 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 PRP81219.1 - 3.1e-19 68.9 12.7 7.7e-19 67.6 12.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 PRP81219.1 - 7.7e-07 29.6 0.7 4.2e-06 27.2 0.3 2.3 2 0 0 2 2 2 1 PH domain FYVE_2 PF02318.16 PRP81219.1 - 0.0011 19.1 4.5 0.0034 17.6 4.5 1.9 1 0 0 1 1 1 1 FYVE-type zinc finger PH_13 PF16652.5 PRP81219.1 - 0.0015 18.4 0.8 0.079 12.8 0.8 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain HypA PF01155.19 PRP81219.1 - 0.19 11.8 2.4 0.46 10.5 1.4 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_2 PF14445.6 PRP81219.1 - 2.2 8.5 9.3 0.7 10.1 5.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 RRM_1 PF00076.22 PRP81221.1 - 2.2e-35 120.3 0.0 2.9e-12 46.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PRP81221.1 - 4.9e-06 26.4 0.2 0.0002 21.3 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 PRP81221.1 - 1.6e-05 24.5 0.0 0.01 15.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP81221.1 - 2.3e-05 24.4 0.2 0.15 12.2 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 PRP81221.1 - 0.18 11.7 0.0 0.88 9.5 0.0 2.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif DUF1206 PF06724.11 PRP81222.1 - 1.4e-19 69.9 22.3 4.7e-10 39.4 5.0 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) Cation_ATPase_C PF00689.21 PRP81222.1 - 0.21 11.3 5.7 0.049 13.3 1.0 2.0 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF2269 PF10027.9 PRP81222.1 - 0.25 11.4 3.9 0.63 10.1 0.4 2.5 1 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Yip1 PF04893.17 PRP81222.1 - 0.96 9.1 18.3 0.28 10.9 10.8 2.4 1 1 1 2 2 2 0 Yip1 domain Mito_carr PF00153.27 PRP81223.1 - 8.5e-78 256.4 3.0 5.1e-27 93.6 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein GST_C PF00043.25 PRP81223.1 - 4.5e-08 33.2 0.0 6.9e-07 29.4 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP81223.1 - 7.4e-07 29.5 0.0 1.6e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP81223.1 - 0.00027 21.1 0.0 0.00084 19.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP81223.1 - 0.0033 17.4 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Serine_protease PF18405.1 PRP81223.1 - 0.03 13.5 1.0 1.2 8.2 0.0 2.6 2 1 0 3 3 3 0 Gammaproteobacterial serine protease EamA PF00892.20 PRP81224.1 - 9.5e-27 93.8 45.7 3.6e-14 53.1 17.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 PRP81224.1 - 0.0012 18.4 9.5 0.0012 18.4 9.5 2.2 1 1 1 2 2 2 2 Solute carrier family 35 VASt PF16016.5 PRP81225.1 - 9.5e-09 35.8 0.1 1.7e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain XhlA PF10779.9 PRP81225.1 - 0.0012 19.0 0.7 0.1 12.8 0.3 2.7 3 0 0 3 3 3 1 Haemolysin XhlA Tropomyosin PF00261.20 PRP81225.1 - 0.043 13.2 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin DUF4254 PF14063.6 PRP81225.1 - 0.052 13.4 3.4 4.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) cwf21 PF08312.12 PRP81225.1 - 0.53 10.5 2.5 1.1 9.5 2.5 1.5 1 0 0 1 1 1 0 cwf21 domain S-AdoMet_synt_C PF02773.16 PRP81227.1 - 6.4e-67 223.8 0.0 1.2e-66 222.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 PRP81227.1 - 3.5e-45 153.1 0.0 7.2e-45 152.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 PRP81227.1 - 3.3e-43 146.4 0.2 6.6e-43 145.4 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Mnd1 PF03962.15 PRP81228.1 - 1.3e-21 76.6 1.9 1.9e-21 76.1 0.4 2.1 2 0 0 2 2 1 1 Mnd1 HTH domain LRR_8 PF13855.6 PRP81228.1 - 1.1e-20 73.2 30.2 2.3e-11 43.3 6.4 3.2 1 1 3 4 4 4 3 Leucine rich repeat LZ3wCH PF18517.1 PRP81228.1 - 6.1e-15 55.0 4.5 6.6e-15 55.0 0.2 3.0 2 0 0 2 2 2 1 Leucine zipper with capping helix domain LRR_4 PF12799.7 PRP81228.1 - 1.3e-12 47.7 11.9 1.4e-07 31.6 1.9 3.8 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PRP81228.1 - 2.1e-08 33.9 1.9 4.2e-08 33.0 1.9 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP81228.1 - 1.2e-07 31.4 1.8 3.1e-07 30.1 1.8 1.8 1 0 0 1 1 1 1 F-box domain SDA1 PF05285.12 PRP81228.1 - 2.9e-05 23.7 37.2 0.0048 16.4 21.5 2.3 2 0 0 2 2 2 2 SDA1 Mpp10 PF04006.12 PRP81228.1 - 0.00023 19.8 19.7 0.00023 19.8 19.7 2.9 3 0 0 3 3 3 1 Mpp10 protein LRR_1 PF00560.33 PRP81228.1 - 0.0012 19.1 9.9 3.9 8.4 0.3 4.8 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP81228.1 - 0.0029 17.5 11.4 0.63 10.2 0.2 4.2 4 0 0 4 4 4 2 Leucine Rich repeat Connexin PF00029.19 PRP81228.1 - 0.003 17.4 5.0 0.003 17.4 5.0 1.7 2 0 0 2 2 1 1 Connexin MDM1 PF15501.6 PRP81228.1 - 0.0041 16.3 9.4 0.0041 16.3 9.4 2.0 2 0 0 2 2 2 1 Nuclear protein MDM1 DDHD PF02862.17 PRP81228.1 - 0.005 17.0 2.4 0.005 17.0 2.4 2.2 2 0 0 2 2 2 1 DDHD domain UPF0242 PF06785.11 PRP81228.1 - 0.015 15.4 0.2 0.015 15.4 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Zip PF02535.22 PRP81228.1 - 0.14 11.4 4.6 0.22 10.7 4.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 PRP81228.1 - 0.2 11.8 18.3 0.18 12.0 12.2 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 PRP81228.1 - 0.8 9.1 18.1 0.019 14.4 10.6 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) MDM10 PF12519.8 PRP81228.1 - 0.99 8.2 6.2 1.9 7.2 6.2 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 EIIBC-GUT_N PF03612.14 PRP81228.1 - 2.9 7.6 8.2 8.5 6.1 8.2 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RNA_pol_Rpc4 PF05132.14 PRP81228.1 - 3.3 8.1 15.2 0.22 11.9 8.4 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ureide_permease PF07168.11 PRP81228.1 - 3.6 6.2 7.4 7.1 5.3 7.4 1.4 1 0 0 1 1 1 0 Ureide permease DUF2203 PF09969.9 PRP81228.1 - 7.3 7.3 14.8 3.1 8.6 0.4 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Presenilin PF01080.17 PRP81228.1 - 9.2 4.9 17.3 0.17 10.6 10.2 1.6 2 0 0 2 2 2 0 Presenilin Glyco_hydro_18 PF00704.28 PRP81229.1 - 1.9e-18 67.2 0.1 7e-18 65.4 0.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Opy2 PF09463.10 PRP81231.1 - 1.2e-14 54.3 54.1 6e-08 32.9 19.4 3.1 3 0 0 3 3 3 3 Opy2 protein GARS_A PF01071.19 PRP81232.1 - 2.6e-77 259.0 0.0 3.8e-77 258.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 PRP81232.1 - 3.3e-35 120.7 0.1 1.2e-34 118.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 PRP81232.1 - 1.4e-32 113.0 0.0 3.8e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 PRP81232.1 - 4.2e-29 100.6 0.1 1.2e-28 99.2 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 PRP81232.1 - 1.4e-15 57.7 0.3 8.8e-15 55.1 0.3 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain RimK PF08443.11 PRP81232.1 - 9.8e-05 22.0 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 PRP81232.1 - 0.036 13.6 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.22 PRP81232.1 - 0.047 13.3 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.14 PRP81232.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DUF1003 PF06210.11 PRP81232.1 - 0.094 12.8 0.7 0.18 12.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) HpaB PF03241.13 PRP81232.1 - 0.11 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal ATPgrasp_ST PF14397.6 PRP81232.1 - 0.13 11.5 0.0 0.89 8.7 0.1 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 PRP81232.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain PH PF00169.29 PRP81233.1 - 0.1 13.1 0.1 0.51 10.9 0.0 2.2 3 0 0 3 3 3 0 PH domain EF-hand_7 PF13499.6 PRP81235.1 - 2.1e-11 44.1 0.3 1.9e-09 37.8 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP81235.1 - 4.8e-07 29.2 0.1 0.0028 17.5 0.0 3.2 3 1 1 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 PRP81235.1 - 2.3e-05 24.6 0.0 0.0042 17.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 PRP81235.1 - 9.8e-05 22.1 0.2 0.00072 19.3 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP81235.1 - 0.0016 17.8 6.1 0.0036 16.7 0.0 3.9 5 0 0 5 5 5 1 EF hand Lipoprotein_Ltp PF07553.11 PRP81235.1 - 0.012 15.9 0.5 0.5 10.7 0.1 2.4 2 0 0 2 2 2 0 Host cell surface-exposed lipoprotein FHA_2 PF17913.1 PRP81235.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 FHA domain ATP-grasp_3 PF02655.14 PRP81236.1 - 6.9e-07 29.4 0.0 1.7e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain JAB PF01398.21 PRP81238.1 - 1.8e-11 44.1 0.0 4.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PRP81238.1 - 1.4e-08 34.6 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-binding PF00249.31 PRP81238.1 - 9.4e-07 28.9 0.1 2.9e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cyt-b5 PF00173.28 PRP81239.1 - 4.8e-18 65.1 0.0 7.2e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PAP2 PF01569.21 PRP81240.1 - 1e-24 86.9 5.6 1e-24 86.9 5.6 1.8 2 0 0 2 2 2 1 PAP2 superfamily Intg_mem_TP0381 PF09529.10 PRP81240.1 - 0.00082 19.0 2.5 0.00082 19.0 2.5 1.8 1 1 1 2 2 2 1 Integral membrane protein (intg_mem_TP0381) DUF2157 PF09925.9 PRP81240.1 - 0.0033 17.2 1.2 1.8 8.4 0.3 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2157) Frag1 PF10277.9 PRP81240.1 - 0.0072 15.9 2.5 0.015 14.8 2.1 1.7 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family Peptidase_U4 PF03419.13 PRP81240.1 - 0.024 14.0 0.6 4.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF983 PF06170.12 PRP81240.1 - 0.46 10.9 5.4 0.15 12.5 1.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF983) DUF4131 PF13567.6 PRP81240.1 - 2.5 7.7 10.9 3.1 7.4 3.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Glucos_trans_II PF14264.6 PRP81240.1 - 2.6 7.3 11.9 0.28 10.5 1.9 2.7 2 1 0 3 3 3 0 Glucosyl transferase GtrII FtsX PF02687.21 PRP81240.1 - 2.8 8.5 9.2 1.5 9.3 3.5 2.8 1 1 1 2 2 2 0 FtsX-like permease family PX PF00787.24 PRP81241.1 - 2e-22 79.3 0.8 2.6e-22 78.9 0.8 1.1 1 0 0 1 1 1 1 PX domain Ribosomal_60s PF00428.19 PRP81242.1 - 1.3e-28 99.4 4.1 1.5e-28 99.2 4.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ABC_transp_aux PF09822.9 PRP81243.1 - 3.4e-08 33.3 0.0 6.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 PRP81243.1 - 2.2e-05 23.5 0.0 4.5e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 PRP81243.1 - 0.01 16.2 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) PH_6 PF15406.6 PRP81245.1 - 0.23 11.8 3.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Hid1 PF12722.7 PRP81245.1 - 1.5 6.8 12.1 2.3 6.2 12.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Podoplanin PF05808.11 PRP81245.1 - 5.4 7.1 13.8 12 6.0 13.8 1.5 1 0 0 1 1 1 0 Podoplanin MORN PF02493.20 PRP81246.1 - 5.9e-75 242.9 146.5 1.3e-07 31.1 1.2 17.5 17 0 0 17 17 17 17 MORN repeat TIG PF01833.24 PRP81246.1 - 2.1e-16 59.8 2.2 1.6e-07 31.3 0.0 2.8 2 0 0 2 2 2 2 IPT/TIG domain FYVE PF01363.21 PRP81246.1 - 1.3e-05 25.3 1.7 1.3e-05 25.3 1.7 1.9 2 0 0 2 2 2 1 FYVE zinc finger WH1 PF00568.23 PRP81246.1 - 0.0079 16.1 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 WH1 domain CHASE6_C PF17150.4 PRP81246.1 - 0.032 14.9 0.1 0.27 11.9 0.1 2.4 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain ANTH PF07651.16 PRP81246.1 - 0.15 11.0 2.6 0.29 10.1 2.6 1.3 1 0 0 1 1 1 0 ANTH domain FYVE_2 PF02318.16 PRP81246.1 - 1.7 8.9 8.1 0.25 11.6 1.8 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Aminotran_1_2 PF00155.21 PRP81247.1 - 3.7e-86 289.6 0.0 4.2e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Choline_transpo PF04515.12 PRP81248.1 - 1.9e-63 214.7 31.4 1.9e-63 214.7 31.4 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF962 PF06127.11 PRP81248.1 - 0.034 14.2 0.1 0.72 10.0 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Peptidase_S49_N PF08496.10 PRP81249.1 - 1 9.4 3.6 2.2 8.3 3.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3886 PF13025.6 PRP81249.1 - 8.1 6.7 17.9 3.8 7.8 9.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF4395 PF14340.6 PRP81250.1 - 1.8e-22 80.0 10.8 1.8e-22 80.0 10.8 2.5 3 1 0 3 3 3 1 Domain of unknown function (DUF4395) RNase_Zc3h12a PF11977.8 PRP81252.1 - 1.9e-14 53.7 0.0 4.9e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain VanW PF04294.13 PRP81252.1 - 0.11 12.2 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 VanW like protein Pkinase PF00069.25 PRP81253.1 - 7.9e-67 225.4 0.0 1e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81253.1 - 1.7e-44 152.1 0.0 2.5e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 PRP81253.1 - 1.5e-19 70.1 1.9 1.8e-19 69.8 0.2 2.1 3 0 0 3 3 3 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 PRP81253.1 - 1.5e-05 24.0 0.0 2.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP81253.1 - 0.0025 17.2 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like BNIP2 PF12496.8 PRP81256.1 - 0.064 13.7 1.8 0.087 13.3 1.8 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PCAF_N PF06466.11 PRP81257.1 - 2.6e-22 79.6 3.7 1.3e-15 57.7 0.1 2.4 2 0 0 2 2 2 2 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 PRP81257.1 - 1.7e-21 76.1 2.7 2.5e-21 75.5 0.6 2.2 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 PRP81257.1 - 3.3e-09 37.0 0.0 7.7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP81257.1 - 1.2e-06 28.5 0.1 3.1e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP81257.1 - 0.00034 21.0 0.2 0.00081 19.8 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SAP PF02037.27 PRP81260.1 - 0.035 13.9 4.4 0.4 10.5 0.0 3.8 5 0 0 5 5 5 0 SAP domain DUF87 PF01935.17 PRP81260.1 - 2.5 8.1 6.9 8.3 6.4 1.4 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain LMBR1 PF04791.16 PRP81262.1 - 3.4e-36 125.2 19.2 1.4e-27 96.8 4.1 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein Claudin_3 PF06653.11 PRP81262.1 - 1.2 9.0 9.8 0.79 9.6 3.9 2.9 3 0 0 3 3 3 0 Tight junction protein, Claudin-like Homeodomain PF00046.29 PRP81263.1 - 6.4e-16 57.9 4.0 9.3e-16 57.4 4.0 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP81263.1 - 0.0069 16.3 0.3 0.012 15.5 0.3 1.4 1 0 0 1 1 1 1 Homeobox KN domain PA_decarbox PF05870.11 PRP81265.1 - 9.3e-11 41.6 0.2 1.2e-10 41.2 0.2 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) LIFR_N PF18207.1 PRP81265.1 - 0.05 14.0 0.2 0.087 13.2 0.2 1.4 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain Glyco_hydro_18 PF00704.28 PRP81266.1 - 2.2e-59 201.7 7.1 2.2e-59 201.7 7.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 PRP81266.1 - 8.7e-54 182.6 0.0 1.2e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81266.1 - 1.5e-27 96.5 0.0 2.1e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase X8 PF07983.13 PRP81266.1 - 8.1e-11 42.5 4.3 3.1e-10 40.6 4.3 2.1 1 0 0 1 1 1 1 X8 domain PAN_4 PF14295.6 PRP81266.1 - 6.3e-09 35.6 5.2 1.7e-08 34.2 5.2 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PRP81266.1 - 0.0014 18.6 0.6 0.0037 17.2 0.6 1.7 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP81266.1 - 0.011 15.8 3.2 0.029 14.5 3.2 1.6 1 0 0 1 1 1 0 PAN-like domain APH PF01636.23 PRP81266.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PRP81266.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RE_AspBHI_N PF18062.1 PRP81266.1 - 0.026 14.1 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal FTA2 PF13095.6 PRP81266.1 - 0.037 13.7 0.0 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAN_3 PF08277.12 PRP81266.1 - 0.24 11.2 4.3 0.66 9.8 1.8 2.6 2 0 0 2 2 2 0 PAN-like domain DUF3011 PF11218.8 PRP81267.1 - 0.052 13.5 0.1 0.06 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) Lipase_3 PF01764.25 PRP81268.1 - 4.2e-31 107.7 0.0 7.4e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PHD PF00628.29 PRP81269.1 - 2.9e-13 49.5 27.8 6.1e-10 38.8 10.8 5.0 3 1 2 5 5 5 3 PHD-finger HMG_box PF00505.19 PRP81269.1 - 5.9e-05 23.4 8.7 0.00015 22.1 8.7 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PRP81269.1 - 8.9e-05 23.0 4.7 0.00026 21.5 4.7 1.8 1 0 0 1 1 1 1 HMG-box domain PHD_2 PF13831.6 PRP81269.1 - 0.0017 17.9 1.3 0.0017 17.9 1.3 5.1 4 2 0 4 4 4 2 PHD-finger Requiem_N PF14051.6 PRP81269.1 - 0.014 15.5 0.1 0.014 15.5 0.1 3.1 3 0 0 3 3 3 0 N-terminal domain of DPF2/REQ. RAG2_PHD PF13341.6 PRP81269.1 - 0.13 12.4 7.5 0.36 10.9 7.5 1.8 1 0 0 1 1 1 0 RAG2 PHD domain Pro-kuma_activ PF09286.11 PRP81270.1 - 3.7e-32 111.6 0.1 6e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP81270.1 - 0.00043 19.6 0.1 0.00097 18.5 0.1 1.5 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 PRP81271.1 - 7.2e-32 110.6 0.1 1.4e-31 109.7 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP81271.1 - 0.001 18.4 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Subtilase family Integrin_beta PF00362.18 PRP81271.1 - 0.11 12.2 1.4 0.81 9.3 0.1 2.3 2 0 0 2 2 2 0 Integrin beta chain VWA domain PHD PF00628.29 PRP81272.1 - 7e-15 54.7 65.5 6.1e-10 38.8 10.8 5.0 3 1 2 5 5 5 3 PHD-finger HMG_box PF00505.19 PRP81272.1 - 6.2e-05 23.3 8.7 0.00015 22.1 8.7 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PRP81272.1 - 9e-05 23.0 4.7 0.00026 21.5 4.7 1.8 1 0 0 1 1 1 1 HMG-box domain PHD_2 PF13831.6 PRP81272.1 - 0.0017 17.9 1.3 0.0017 17.9 1.3 5.4 4 2 0 4 4 4 2 PHD-finger Requiem_N PF14051.6 PRP81272.1 - 0.015 15.5 0.1 0.015 15.5 0.1 3.1 3 0 0 3 3 3 0 N-terminal domain of DPF2/REQ. RAG2_PHD PF13341.6 PRP81272.1 - 0.13 12.3 7.5 0.36 10.9 7.5 1.8 1 0 0 1 1 1 0 RAG2 PHD domain Lipase_3 PF01764.25 PRP81273.1 - 2.1e-31 108.7 0.0 3.5e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 PRP81273.1 - 0.11 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF624 PF04854.14 PRP81273.1 - 0.31 11.2 1.7 0.4 10.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF624 Pkinase PF00069.25 PRP81275.1 - 7.7e-108 359.8 0.0 6.7e-54 183.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Glyco_hydro_18 PF00704.28 PRP81275.1 - 3.8e-59 201.0 7.1 3.8e-59 201.0 7.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Pkinase_Tyr PF07714.17 PRP81275.1 - 1.1e-57 195.3 0.0 1e-27 97.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase X8 PF07983.13 PRP81275.1 - 1.4e-10 41.7 4.3 4.5e-10 40.1 4.3 2.0 1 0 0 1 1 1 1 X8 domain PAN_4 PF14295.6 PRP81275.1 - 8.8e-09 35.1 5.2 2.5e-08 33.7 5.2 1.9 1 0 0 1 1 1 1 PAN domain APH PF01636.23 PRP81275.1 - 1.8e-07 31.4 0.1 0.026 14.5 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP81275.1 - 1.1e-06 28.2 0.3 0.059 12.7 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP81275.1 - 1.4e-06 28.1 0.0 0.86 9.2 0.0 4.0 4 0 0 4 4 4 2 Kinetochore Sim4 complex subunit FTA2 PAN_1 PF00024.26 PRP81275.1 - 0.002 18.1 0.6 0.0054 16.7 0.6 1.7 1 0 0 1 1 1 1 PAN domain Seadorna_VP7 PF07387.11 PRP81275.1 - 0.007 15.5 0.2 4 6.4 0.0 2.6 2 0 0 2 2 2 2 Seadornavirus VP7 PAN_2 PF08276.11 PRP81275.1 - 0.016 15.3 3.2 0.041 14.0 3.2 1.6 1 0 0 1 1 1 0 PAN-like domain RE_AspBHI_N PF18062.1 PRP81275.1 - 0.039 13.5 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal Grp7_allergen PF16984.5 PRP81275.1 - 0.043 13.9 0.0 17 5.4 0.0 2.6 2 0 0 2 2 2 0 Group 7 allergen Stanniocalcin PF03298.13 PRP81275.1 - 0.071 12.4 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Stanniocalcin family Sde2_N_Ubi PF13019.6 PRP81275.1 - 0.11 12.3 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Kinase-like PF14531.6 PRP81275.1 - 0.14 11.5 0.0 21 4.3 0.0 2.5 2 2 0 2 2 2 0 Kinase-like PAN_3 PF08277.12 PRP81275.1 - 1.1 9.1 6.3 0.94 9.3 1.8 2.9 3 0 0 3 3 3 0 PAN-like domain PA_decarbox PF05870.11 PRP81276.1 - 1.1e-10 41.4 0.2 1.5e-10 41.0 0.2 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) LIFR_N PF18207.1 PRP81276.1 - 0.055 13.9 0.2 0.096 13.1 0.2 1.4 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain Ank_2 PF12796.7 PRP81277.1 - 0.072 13.7 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Homeodomain PF00046.29 PRP81279.1 - 2.3e-15 56.2 4.0 4.3e-15 55.3 4.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP81279.1 - 0.023 14.6 1.0 0.041 13.8 0.3 1.8 2 0 0 2 2 2 0 Homeobox KN domain LMBR1 PF04791.16 PRP81280.1 - 2.5e-36 125.7 19.3 1.1e-27 97.2 3.9 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein SAP PF02037.27 PRP81282.1 - 0.035 13.9 4.4 0.4 10.5 0.0 3.8 5 0 0 5 5 5 0 SAP domain DUF87 PF01935.17 PRP81282.1 - 2.5 8.1 6.9 8.3 6.4 1.4 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain PCAF_N PF06466.11 PRP81284.1 - 2.7e-22 79.6 3.7 1.3e-15 57.7 0.1 2.4 2 0 0 2 2 2 2 PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain PF00439.25 PRP81284.1 - 1.7e-21 76.0 2.7 2.5e-21 75.5 0.6 2.2 2 0 0 2 2 2 1 Bromodomain Acetyltransf_1 PF00583.25 PRP81284.1 - 3.3e-09 37.0 0.0 8e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP81284.1 - 1.2e-06 28.5 0.1 3.2e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP81284.1 - 0.00034 21.0 0.2 0.00083 19.7 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase PF00069.25 PRP81285.1 - 1.7e-54 185.0 0.0 2.1e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81285.1 - 6.6e-27 94.4 0.0 8.4e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PRP81285.1 - 9.1e-06 25.4 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PRP81285.1 - 7.9e-05 22.7 0.1 0.0023 17.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP81285.1 - 0.00018 20.9 0.1 0.00028 20.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP81285.1 - 0.0027 17.3 0.0 0.0039 16.8 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 PRP81285.1 - 0.016 14.9 0.0 0.023 14.3 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PRP81285.1 - 0.076 11.8 0.0 0.52 9.0 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 PRP81287.1 - 4.3e-57 193.5 0.0 6.4e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81287.1 - 7.2e-29 100.9 0.0 9.1e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PRP81287.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PRP81287.1 - 0.00012 21.8 0.0 0.06 13.0 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PRP81287.1 - 0.00019 21.5 0.2 0.0059 16.6 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP81287.1 - 0.00053 19.4 0.0 0.0008 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP81287.1 - 0.0048 16.5 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PRP81287.1 - 0.038 12.8 0.1 2.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase PAN_4 PF14295.6 PRP81288.1 - 1.3e-08 34.6 4.0 3.9e-08 33.1 4.0 1.9 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP81288.1 - 0.032 14.3 1.9 0.087 13.0 1.9 1.7 1 0 0 1 1 1 0 PAN-like domain Pkinase PF00069.25 PRP81289.1 - 1.4e-52 178.7 0.0 1.7e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81289.1 - 1.8e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PRP81289.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PRP81289.1 - 0.00094 19.2 0.2 0.0021 18.0 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP81289.1 - 0.0043 16.4 0.3 0.0076 15.6 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP81289.1 - 0.0058 16.3 0.0 0.27 10.8 0.0 2.2 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 PRP81289.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 PRP81289.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RicinB_lectin_2 PF14200.6 PRP81290.1 - 1.2e-08 35.6 0.6 7.1e-06 26.7 0.0 3.2 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_18 PF00704.28 PRP81293.1 - 3.2e-62 211.1 1.1 3.7e-62 210.8 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 PRP81294.1 - 2.4e-48 164.8 0.0 3.6e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81294.1 - 1.2e-25 90.2 0.0 2.1e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 PRP81294.1 - 2.1e-16 60.1 0.1 3.7e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 C2 domain APH PF01636.23 PRP81294.1 - 0.0037 17.2 0.0 0.0066 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP81294.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PRP81295.1 - 4.3e-157 521.3 0.0 7.7e-53 179.5 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81295.1 - 4.8e-84 281.7 0.0 2.7e-28 99.0 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 PRP81295.1 - 1.3e-12 48.2 0.8 0.011 15.7 0.0 3.5 3 0 0 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.14 PRP81295.1 - 6.4e-12 45.3 0.8 0.0069 15.8 0.0 3.4 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP81295.1 - 5.1e-08 32.8 0.1 0.52 9.9 0.0 4.6 5 0 0 5 5 5 3 Kinetochore Sim4 complex subunit FTA2 Grp7_allergen PF16984.5 PRP81295.1 - 2.3e-06 27.8 1.7 0.57 10.2 0.0 4.0 5 0 0 5 5 5 3 Group 7 allergen Kinase-like PF14531.6 PRP81295.1 - 0.00051 19.5 1.5 8.9 5.5 0.0 4.1 3 3 0 3 3 3 2 Kinase-like Seadorna_VP7 PF07387.11 PRP81295.1 - 0.00085 18.5 3.2 3.6 6.6 0.1 3.2 3 0 0 3 3 3 2 Seadornavirus VP7 DUF4953 PF16313.5 PRP81295.1 - 0.0012 18.1 0.3 4.9 6.3 0.0 3.8 4 0 0 4 4 4 1 Met-zincin PIP49_C PF12260.8 PRP81295.1 - 0.018 14.7 0.0 32 4.1 0.0 3.2 3 0 0 3 3 3 0 Protein-kinase domain of FAM69 Pox_ser-thr_kin PF05445.11 PRP81295.1 - 0.045 12.7 1.5 31 3.4 0.0 3.7 4 0 0 4 4 4 0 Poxvirus serine/threonine protein kinase Stanniocalcin PF03298.13 PRP81295.1 - 0.094 12.0 0.0 34 3.7 0.0 3.1 3 0 0 3 3 3 0 Stanniocalcin family Gb3_synth PF04572.12 PRP81295.1 - 0.21 11.8 0.0 36 4.6 0.0 2.4 2 0 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region Haspin_kinase PF12330.8 PRP81295.1 - 0.28 10.1 1.4 97 1.7 0.0 4.2 6 0 0 6 6 6 0 Haspin like kinase domain FeoB_C PF07664.12 PRP81295.1 - 4.2 7.1 4.8 36 4.1 0.7 2.8 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus Exo_endo_phos PF03372.23 PRP81296.1 - 2.3e-05 24.0 0.0 4.4e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase_Tyr PF07714.17 PRP81297.1 - 6.7e-48 163.2 0.0 9.2e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81297.1 - 1.3e-44 152.5 0.0 2e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP81297.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP81297.1 - 0.0035 16.2 0.0 0.006 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PRP81297.1 - 0.0066 16.4 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP81297.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Rhomboid PF01694.22 PRP81298.1 - 1.7e-06 28.1 10.6 1.7e-06 28.1 10.6 2.2 1 1 2 3 3 3 1 Rhomboid family GATA PF00320.27 PRP81298.1 - 2.7e-06 26.9 0.3 5.7e-06 25.8 0.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DER1 PF04511.15 PRP81298.1 - 7.4e-05 22.8 0.2 7.4e-05 22.8 0.2 2.7 2 1 1 3 3 3 1 Der1-like family LCAT PF02450.15 PRP81300.1 - 6.5e-31 107.9 0.2 8.3e-26 91.1 0.0 2.6 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Pkinase PF00069.25 PRP81302.1 - 9.8e-65 218.5 0.0 3e-64 216.9 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81302.1 - 4.7e-43 147.3 0.0 1.1e-42 146.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP81302.1 - 1.1e-05 24.4 5.2 0.00014 20.8 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 PRP81302.1 - 0.023 14.3 0.9 0.051 13.2 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4704 PF15787.5 PRP81302.1 - 0.068 12.4 3.4 0.37 10.0 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4704) HEAT_2 PF13646.6 PRP81302.1 - 0.15 12.4 0.2 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 HEAT repeats HEAT PF02985.22 PRP81302.1 - 0.59 10.6 3.9 12 6.5 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Pkinase PF00069.25 PRP81304.1 - 8.7e-57 192.5 0.0 1.7e-50 171.8 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81304.1 - 1.4e-29 103.2 0.0 2.1e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP81304.1 - 0.00025 21.1 0.0 0.00075 19.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP81304.1 - 0.0007 19.0 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP81304.1 - 0.00087 19.0 0.0 0.34 10.5 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP81304.1 - 0.0026 17.1 0.0 0.0083 15.5 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 PRP81304.1 - 0.0029 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Grp7_allergen PF16984.5 PRP81304.1 - 0.092 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Group 7 allergen YrbL-PhoP_reg PF10707.9 PRP81304.1 - 0.092 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 PRP81305.1 - 4e-29 101.8 2.3 9.9e-29 100.5 2.3 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81305.1 - 1.5e-26 93.2 2.0 1.9e-25 89.6 1.7 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP81305.1 - 1.1e-07 32.3 6.9 1.1e-07 32.3 6.9 2.6 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP81305.1 - 0.00012 21.5 0.0 0.0051 16.2 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP81305.1 - 0.0034 16.8 0.1 0.0054 16.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_8 PF13833.6 PRP81306.1 - 8.3e-16 57.6 1.7 2.2e-08 33.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP81306.1 - 3e-14 51.4 0.0 3.6e-06 26.1 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PRP81306.1 - 2.7e-11 43.8 0.3 2.4e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP81306.1 - 3e-10 39.2 0.2 6.7e-05 22.5 0.0 3.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP81306.1 - 1.5e-06 27.4 0.2 0.0002 20.7 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 PRP81306.1 - 0.0001 22.5 0.1 0.0038 17.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain UPF0154 PF03672.13 PRP81306.1 - 0.00073 19.5 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 PRP81306.1 - 0.04 14.8 0.0 0.058 14.3 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain PPR_3 PF13812.6 PRP81307.1 - 2.7e-26 91.4 0.3 7.9e-10 38.7 0.3 4.5 3 1 0 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 PRP81307.1 - 2.9e-22 78.6 2.1 1.2e-11 44.6 0.1 4.6 2 1 2 4 4 4 4 PPR repeat family PPR PF01535.20 PRP81307.1 - 1.4e-11 43.8 2.4 0.0057 16.8 0.1 5.3 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 PRP81307.1 - 4.9e-10 39.1 0.0 2.9e-07 30.1 0.0 2.6 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP81307.1 - 5.2e-06 26.1 0.7 0.21 11.3 0.0 4.2 4 0 0 4 4 4 2 PPR repeat Clathrin PF00637.20 PRP81307.1 - 0.007 16.2 0.3 0.17 11.7 0.0 3.0 2 1 2 4 4 4 1 Region in Clathrin and VPS MRP-S27 PF10037.9 PRP81307.1 - 0.011 14.6 0.1 0.019 13.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Vma12 PF11712.8 PRP81308.1 - 3.4e-19 69.3 0.0 5.8e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1940 PF09155.10 PRP81308.1 - 0.037 14.2 0.2 12 6.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1940) DUF2175 PF09943.9 PRP81308.1 - 0.92 9.8 6.1 0.44 10.9 2.9 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) PKD_channel PF08016.12 PRP81309.1 - 2.9e-47 161.3 9.8 4.6e-47 160.6 9.8 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ank_4 PF13637.6 PRP81309.1 - 0.00076 20.0 0.3 0.058 14.0 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81309.1 - 0.001 19.6 0.5 0.17 12.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) PQQ_3 PF13570.6 PRP81309.1 - 0.025 15.1 1.6 23 5.6 0.1 5.3 5 1 0 5 5 5 0 PQQ-like domain Metallophos PF00149.28 PRP81310.1 - 2.7e-16 60.7 0.2 4.2e-16 60.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PRP81310.1 - 2.4e-12 47.2 0.2 6.8e-12 45.8 0.2 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3_PAP PF17808.1 PRP81310.1 - 2e-06 27.9 1.0 0.00011 22.3 0.6 3.2 2 1 0 2 2 2 1 Fn3-like domain from Purple Acid Phosphatase Metallophos_C PF14008.6 PRP81310.1 - 0.0047 17.8 0.9 0.016 16.1 0.9 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 PRP81310.1 - 0.059 13.6 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Aft1_OSA PF11785.8 PRP81311.1 - 0.086 13.3 3.4 0.38 11.2 0.3 2.4 2 0 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain IBR PF01485.21 PRP81313.1 - 5.6e-09 36.1 38.9 3.8e-08 33.4 7.6 4.4 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PRP81313.1 - 1.3e-06 28.6 2.5 1.3e-06 28.6 2.5 4.3 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 PRP81313.1 - 7.7e-06 25.8 1.2 7.7e-06 25.8 1.2 3.9 4 2 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP81313.1 - 0.00054 19.8 2.5 0.00054 19.8 2.5 5.6 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP81313.1 - 0.00097 19.0 1.8 0.00097 19.0 1.8 4.7 4 1 0 4 4 4 1 zinc-RING finger domain Lipoprotein_8 PF02030.15 PRP81314.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) HisG PF01634.18 PRP81315.1 - 1.2e-52 178.1 0.3 1.7e-52 177.6 0.3 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 PRP81315.1 - 2e-24 85.5 0.1 4.7e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 PRP81315.1 - 0.024 14.6 0.1 0.039 13.9 0.1 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Bromodomain PF00439.25 PRP81316.1 - 1e-24 86.4 0.0 2.5e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Bromodomain Myb_DNA-binding PF00249.31 PRP81316.1 - 8.2e-05 22.7 0.2 0.0002 21.5 0.2 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP81316.1 - 0.0023 18.2 0.0 0.0071 16.6 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF4795 PF16043.5 PRP81317.1 - 0.0023 17.5 5.9 0.0085 15.7 5.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) Tektin PF03148.14 PRP81317.1 - 0.011 14.6 1.2 0.15 10.8 1.0 2.3 2 0 0 2 2 2 0 Tektin family RA PF00788.23 PRP81317.1 - 0.019 15.6 0.4 0.24 12.0 0.0 2.4 1 1 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Bap31_Bap29_C PF18035.1 PRP81317.1 - 0.022 14.7 3.6 0.052 13.6 3.6 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain PI3K_rbd PF00794.18 PRP81317.1 - 0.04 14.1 0.1 0.32 11.2 0.0 2.4 3 0 0 3 3 3 0 PI3-kinase family, ras-binding domain YabA PF06156.13 PRP81317.1 - 0.12 13.0 1.2 0.44 11.2 0.6 2.2 2 0 0 2 2 2 0 Initiation control protein YabA CENP-H PF05837.12 PRP81317.1 - 0.32 11.4 4.9 0.21 12.0 1.5 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Myosin_tail_1 PF01576.19 PRP81317.1 - 0.59 7.9 9.9 0.046 11.5 2.7 2.0 2 0 0 2 2 2 0 Myosin tail Prefoldin_2 PF01920.20 PRP81317.1 - 4.6 7.3 9.7 2.4 8.2 5.0 2.8 2 1 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 PRP81317.1 - 7.8 6.6 7.2 0.53 10.3 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Abhydrolase_2 PF02230.16 PRP81318.1 - 4.3e-12 46.3 0.0 1.4e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 PRP81318.1 - 3e-08 33.5 0.0 4.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PRP81318.1 - 5.5e-07 29.3 0.2 0.00021 20.9 0.2 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PRP81318.1 - 6.2e-06 25.7 0.3 5.4e-05 22.6 0.1 2.3 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 PRP81318.1 - 0.00067 19.2 0.0 1 8.8 0.0 2.5 2 1 1 3 3 3 2 Esterase PHB depolymerase Esterase PF00756.20 PRP81318.1 - 0.0013 18.5 0.0 0.48 10.0 0.0 2.2 1 1 1 2 2 2 2 Putative esterase Abhydrolase_1 PF00561.20 PRP81318.1 - 0.0051 16.5 0.0 0.068 12.8 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP81318.1 - 0.025 15.2 0.0 0.1 13.2 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family LIP PF03583.14 PRP81318.1 - 0.073 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase FSH1 PF03959.13 PRP81318.1 - 0.18 11.5 0.5 0.33 10.6 0.0 1.7 2 1 0 2 2 2 0 Serine hydrolase (FSH1) PP2C PF00481.21 PRP81319.1 - 2.3e-71 240.5 0.1 3.4e-71 239.9 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Galactosyl_T PF01762.21 PRP81319.1 - 1.4e-14 54.4 0.7 6.6e-11 42.4 0.7 2.3 1 1 1 2 2 2 2 Galactosyltransferase GRAM PF02893.20 PRP81319.1 - 0.0039 17.0 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Gly-zipper_YMGG PF13441.6 PRP81319.1 - 0.03 14.1 1.0 0.062 13.0 1.0 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Pkinase PF00069.25 PRP81320.1 - 8.9e-52 176.1 0.0 1.1e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81320.1 - 2.3e-27 95.9 0.0 3.5e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP81320.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP81320.1 - 0.0057 16.0 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP81320.1 - 0.0096 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 PRP81320.1 - 0.1 12.2 0.0 0.4 10.3 0.0 1.7 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP81320.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DENN PF02141.21 PRP81321.1 - 8.1e-28 97.6 0.1 1.7e-27 96.6 0.1 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PRP81321.1 - 5.2e-07 30.3 0.1 1.9e-06 28.5 0.1 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 PRP81321.1 - 0.039 13.9 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 dDENN domain LSM PF01423.22 PRP81322.1 - 1.4e-10 40.7 0.0 6.5e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 LSM domain CpeT PF06206.11 PRP81322.1 - 0.11 12.4 0.3 13 5.6 0.0 3.1 3 0 0 3 3 3 0 CpeT/CpcT family (DUF1001) Pkinase PF00069.25 PRP81323.1 - 3.2e-67 226.7 0.0 2.3e-66 223.9 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81323.1 - 8.8e-43 146.5 0.0 3.8e-42 144.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP81323.1 - 0.00056 19.3 0.0 0.00056 19.3 0.0 2.4 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 PRP81323.1 - 0.0016 17.4 0.6 0.011 14.7 0.2 2.5 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PRP81323.1 - 0.0059 16.6 0.1 0.0059 16.6 0.1 4.6 4 1 1 5 5 5 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PRP81323.1 - 0.018 14.1 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 PRP81323.1 - 0.11 12.1 0.1 0.11 12.1 0.1 4.3 6 0 0 6 6 6 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 PRP81325.1 - 2.5e-23 82.5 0.0 1e-05 26.0 0.0 5.5 2 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81325.1 - 4.2e-13 49.5 0.4 0.056 14.1 0.0 6.3 3 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81325.1 - 5e-12 44.9 0.0 0.0064 16.9 0.0 8.2 9 0 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 PRP81325.1 - 3.1e-09 36.9 0.1 1.9 8.9 0.0 7.0 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP81325.1 - 2.3e-06 27.8 0.5 14 6.4 0.1 7.7 9 2 1 10 10 10 1 Ankyrin repeat FCD PF07729.12 PRP81325.1 - 0.0033 17.8 3.9 0.018 15.5 0.5 3.3 3 1 1 4 4 4 1 FCD domain F-box-like PF12937.7 PRP81325.1 - 0.011 15.7 1.0 0.027 14.4 1.0 1.7 1 1 0 1 1 1 0 F-box-like TerD PF02342.18 PRP81326.1 - 2.1e-20 73.0 0.0 8e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 TerD domain UQ_con PF00179.26 PRP81326.1 - 2.2e-19 69.5 0.0 6.7e-19 67.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box PF00646.33 PRP81326.1 - 1.2e-05 25.1 0.1 3e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP81326.1 - 1.7e-05 24.6 0.2 5e-05 23.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 PRP81326.1 - 0.034 14.0 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 F-box RWD PF05773.22 PRP81326.1 - 0.065 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RWD domain CIAPIN1 PF05093.13 PRP81326.1 - 0.083 13.4 5.5 0.11 13.0 0.0 2.6 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TFIIA PF03153.13 PRP81326.1 - 1.4 8.9 26.0 1.9 8.4 26.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2228 PF10228.9 PRP81326.1 - 4.2 7.0 8.2 10 5.8 8.2 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Membralin PF09746.9 PRP81326.1 - 9.8 5.1 7.8 15 4.5 7.8 1.2 1 0 0 1 1 1 0 Tumour-associated protein Sulfate_transp PF00916.20 PRP81327.1 - 1.8e-99 333.0 24.8 1.3e-93 313.8 18.6 2.2 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 PRP81327.1 - 3.9e-12 45.8 0.0 1.5e-11 44.0 0.0 1.9 2 1 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 PRP81327.1 - 0.00048 20.5 18.9 0.00078 19.8 5.1 3.6 2 1 1 3 3 3 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 PRP81327.1 - 0.0034 17.7 0.2 0.0093 16.3 0.2 1.7 1 0 0 1 1 1 1 STAS domain DEAD PF00270.29 PRP81329.1 - 1.6e-36 125.7 1.1 4.1e-36 124.4 0.4 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP81329.1 - 2.3e-27 95.5 0.2 2.5e-26 92.2 0.1 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP81329.1 - 2.7e-06 27.5 0.0 7.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PRP81329.1 - 0.0014 18.1 1.0 0.047 13.0 0.1 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit LSM PF01423.22 PRP81330.1 - 6.6e-22 77.0 0.2 7.6e-22 76.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain HATPase_c PF02518.26 PRP81331.1 - 1.4e-26 93.2 0.2 2.7e-26 92.3 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP81331.1 - 3.7e-19 68.9 0.9 1.5e-17 63.8 0.1 2.7 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 PRP81331.1 - 2.6e-14 53.0 1.0 6e-14 51.8 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain MASE3 PF17159.4 PRP81331.1 - 4.8e-08 32.9 16.5 7.5e-08 32.3 16.5 1.3 1 0 0 1 1 1 1 Membrane-associated sensor domain HATPase_c_3 PF13589.6 PRP81331.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase sCache_2 PF17200.4 PRP81331.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Single Cache domain 2 Ion_trans_N PF08412.10 PRP81332.1 - 0.01 15.4 0.8 0.068 12.8 0.1 2.5 2 0 0 2 2 2 0 Ion transport protein N-terminal PAS_9 PF13426.7 PRP81332.1 - 0.023 15.0 0.0 0.078 13.2 0.0 2.0 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.7 PRP81332.1 - 0.11 12.6 0.0 0.41 10.7 0.0 2.0 1 1 1 2 2 2 0 PAS domain RicinB_lectin_2 PF14200.6 PRP81334.1 - 1.5e-08 35.2 0.7 1.7e-06 28.7 0.0 3.3 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like VWA_N2 PF16164.5 PRP81334.1 - 0.11 12.7 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 VWA N-terminal Ank_2 PF12796.7 PRP81336.1 - 3.7e-13 49.9 0.0 4.4e-09 36.8 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81336.1 - 7.1e-08 32.9 0.0 0.00093 19.7 0.0 3.6 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81336.1 - 4.3e-05 23.6 0.1 14 6.7 0.0 5.0 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 PRP81336.1 - 0.00073 19.8 0.1 7.3 7.0 0.0 4.2 3 1 2 5 5 5 2 Ankyrin repeats (many copies) DUF2244 PF10003.9 PRP81336.1 - 0.0091 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) F-box PF00646.33 PRP81336.1 - 0.045 13.6 1.2 0.12 12.2 1.2 1.7 1 0 0 1 1 1 0 F-box domain Ank PF00023.30 PRP81336.1 - 0.12 12.9 0.0 1.3e+02 3.3 0.0 4.4 3 2 2 5 5 5 0 Ankyrin repeat ATP-synt_10 PF05176.14 PRP81338.1 - 5.6e-11 42.2 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DNA_circ_N PF07157.12 PRP81338.1 - 0.058 13.8 0.0 1.4 9.4 0.0 2.2 2 0 0 2 2 2 0 DNA circularisation protein N-terminus Biotin_lipoyl PF00364.22 PRP81339.1 - 0.0017 18.2 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 PRP81339.1 - 0.0081 15.4 0.0 0.37 10.0 0.0 2.1 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion zf-Tim10_DDP PF02953.15 PRP81341.1 - 6.6e-10 38.5 1.5 8.2e-10 38.2 1.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Dus PF01207.17 PRP81342.1 - 2.7e-66 223.8 0.0 3.2e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 PRP81342.1 - 0.0059 15.9 0.0 0.013 14.7 0.0 1.5 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 PRP81342.1 - 0.05 13.1 0.1 0.18 11.2 0.1 1.9 1 1 0 1 1 1 0 Histidine biosynthesis protein Oxidored_FMN PF00724.20 PRP81342.1 - 0.053 12.8 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family B12-binding PF02310.19 PRP81342.1 - 0.063 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain TMP-TENI PF02581.17 PRP81342.1 - 0.1 11.9 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase Mito_carr PF00153.27 PRP81343.1 - 1.6e-64 213.9 5.8 5e-24 84.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ACAS_N PF16177.5 PRP81343.1 - 0.032 14.1 0.4 0.062 13.2 0.4 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Fuseless PF15993.5 PRP81343.1 - 0.037 13.2 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 Fuseless DEAD PF00270.29 PRP81344.1 - 2.6e-40 138.0 0.1 2.6e-40 138.0 0.1 3.4 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP81344.1 - 4e-27 94.8 1.2 2.7e-26 92.1 0.0 3.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NPV_P10 PF05531.12 PRP81344.1 - 0.011 16.2 2.3 0.011 16.2 2.3 6.4 5 3 2 7 7 7 0 Nucleopolyhedrovirus P10 protein T2SSG PF08334.11 PRP81344.1 - 0.54 10.4 4.3 29 4.8 1.6 3.4 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein G Myotub-related PF06602.14 PRP81345.1 - 4.7e-122 407.3 0.0 6.9e-122 406.8 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain FYVE PF01363.21 PRP81345.1 - 2e-05 24.6 2.4 0.00073 19.6 2.4 2.6 1 1 0 1 1 1 1 FYVE zinc finger GRAM PF02893.20 PRP81345.1 - 0.0018 18.2 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 PRP81345.1 - 0.003 17.2 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP81345.1 - 0.0033 17.4 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 PRP81345.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain TFIIA PF03153.13 PRP81346.1 - 0.17 11.9 32.0 0.19 11.7 32.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3767 PF12597.8 PRP81347.1 - 1.4e-09 37.7 0.5 1.4e-09 37.7 0.5 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) DUF5475 PF17569.2 PRP81347.1 - 0.034 14.5 1.0 0.05 13.9 1.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5475) EMC3_TMCO1 PF01956.16 PRP81347.1 - 2 8.1 4.8 3.2 7.5 4.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Stimulus_sens_1 PF13756.6 PRP81348.1 - 7.9 7.1 6.5 3.4 8.3 0.1 3.3 3 1 1 4 4 4 0 Stimulus-sensing domain TPR_2 PF07719.17 PRP81349.1 - 3.9e-29 98.4 0.1 3.7e-05 23.5 0.1 9.2 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 PRP81349.1 - 9.3e-24 82.2 8.3 1.2e-05 25.0 0.2 8.9 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP81349.1 - 1.5e-23 80.9 0.1 2.5e-05 24.1 0.1 8.7 8 0 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP81349.1 - 5.7e-21 74.5 11.3 4.3e-08 33.3 0.1 6.3 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PRP81349.1 - 1.6e-16 60.4 5.7 6.1e-08 32.8 0.2 6.6 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP81349.1 - 1.2e-12 47.2 0.0 0.0032 17.1 0.0 6.1 3 2 3 6 6 6 3 TPR repeat TPR_17 PF13431.6 PRP81349.1 - 2.7e-12 46.2 0.3 0.035 14.5 0.0 7.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP81349.1 - 5e-12 45.0 10.0 0.00019 21.2 0.1 7.3 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP81349.1 - 1.2e-11 44.5 0.8 0.063 13.9 0.0 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP81349.1 - 5.1e-11 42.4 0.0 0.56 11.2 0.0 6.7 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP81349.1 - 7.7e-11 42.3 0.0 0.15 12.5 0.0 6.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 PRP81349.1 - 4.1e-10 39.2 2.0 0.018 14.9 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP81349.1 - 7.7e-07 29.7 0.0 0.38 11.4 0.0 5.2 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP81349.1 - 6.8e-05 22.9 0.0 4.4 7.5 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP81349.1 - 0.0049 16.9 0.0 31 4.7 0.1 4.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 PRP81349.1 - 0.0072 16.3 8.1 4.9 7.3 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP81349.1 - 0.012 15.1 0.0 0.046 13.1 0.0 2.1 1 0 0 1 1 1 0 MalT-like TPR region MIT PF04212.18 PRP81349.1 - 0.015 15.4 2.5 0.36 10.9 0.3 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 PRP81349.1 - 0.02 14.9 0.0 0.091 12.8 0.0 2.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) ANAPC8 PF04049.13 PRP81349.1 - 0.028 14.5 1.3 0.058 13.5 0.1 2.1 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_15 PF13429.6 PRP81349.1 - 0.044 13.0 0.0 3 7.0 0.0 3.7 5 1 0 5 5 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 PRP81349.1 - 0.06 13.7 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Gasdermin_C PF17708.1 PRP81349.1 - 0.073 13.2 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Gasdermin PUB domain DUF4919 PF16266.5 PRP81349.1 - 0.081 12.9 0.2 3.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) DUF1947 PF09183.10 PRP81349.1 - 0.34 11.2 2.6 0.25 11.7 0.2 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF1947) Mito_carr PF00153.27 PRP81352.1 - 3.5e-68 225.6 1.3 5.1e-24 84.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 PRP81352.1 - 1.7e-19 67.8 13.3 8.5e-05 21.8 0.2 6.1 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 PRP81352.1 - 6.5e-18 63.1 13.1 0.00059 19.6 0.0 6.0 6 0 0 6 6 6 4 EF-hand domain EF-hand_7 PF13499.6 PRP81352.1 - 1e-16 61.1 7.5 0.0022 18.4 0.1 5.0 4 1 0 5 5 5 4 EF-hand domain pair cNMP_binding PF00027.29 PRP81352.1 - 1.4e-15 57.1 0.0 9.2e-15 54.5 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain EF-hand_8 PF13833.6 PRP81352.1 - 5.9e-15 54.9 7.3 8.2e-07 28.8 0.1 5.4 4 2 2 6 6 6 3 EF-hand domain pair EF-hand_5 PF13202.6 PRP81352.1 - 1e-09 37.4 7.2 0.0032 16.9 0.3 5.1 5 0 0 5 5 5 2 EF hand EF-hand_4 PF12763.7 PRP81352.1 - 0.011 15.7 0.1 4.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 PRP81352.1 - 0.016 15.4 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 Dockerin type I domain CytB6-F_Fe-S PF08802.10 PRP81352.1 - 0.47 10.5 5.8 11 6.2 0.5 2.6 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit TPR_12 PF13424.6 PRP81353.1 - 3.2e-07 30.5 8.7 0.00046 20.4 0.1 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP81353.1 - 4e-06 26.5 10.1 0.032 14.4 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP81353.1 - 9.1e-06 25.3 2.4 0.072 12.4 0.4 2.2 1 1 0 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 PRP81353.1 - 6.8e-05 23.4 5.3 2.9 8.9 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP81353.1 - 0.0005 19.9 6.7 1.5 9.0 0.4 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP81353.1 - 0.002 18.0 7.1 1.2 9.2 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP81353.1 - 0.0028 18.1 5.6 0.028 14.9 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 PRP81353.1 - 0.0047 17.0 3.5 0.39 10.8 0.5 3.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 PRP81353.1 - 0.015 15.0 5.0 0.46 10.2 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 PRP81353.1 - 0.019 14.7 1.0 0.33 10.6 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_1 PF00515.28 PRP81353.1 - 0.02 14.7 0.1 0.02 14.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 PRP81353.1 - 0.035 14.3 0.4 6.1 7.1 0.1 2.2 1 1 0 2 2 2 0 Tetratrico peptide repeat TPR_16 PF13432.6 PRP81353.1 - 0.079 13.6 3.1 6.3 7.5 1.4 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat RPN6_N PF18055.1 PRP81353.1 - 0.14 12.5 2.4 0.26 11.7 0.5 2.3 2 1 0 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_4 PF07721.14 PRP81353.1 - 0.17 12.6 3.1 51 4.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4298 PF14131.6 PRP81353.1 - 0.23 11.4 3.9 0.09 12.7 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) PaREP1 PF05942.11 PRP81353.1 - 0.25 11.3 5.7 0.29 11.1 2.9 2.5 2 1 0 2 2 2 0 Archaeal PaREP1/PaREP8 family TPR_6 PF13174.6 PRP81353.1 - 0.62 10.8 10.3 0.78 10.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP81353.1 - 0.93 9.9 7.5 14 6.2 0.1 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP81353.1 - 2.1 8.1 8.7 7.9 6.3 0.0 3.1 3 1 0 3 3 3 0 TPR repeat Glyco_transf_10 PF00852.19 PRP81354.1 - 4e-32 111.4 0.1 7.5e-32 110.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PRP81354.1 - 8.4e-08 32.6 0.0 2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal Glyco_trans_1_2 PF13524.6 PRP81354.1 - 1.2e-05 25.6 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Exostosin PF03016.15 PRP81354.1 - 0.0075 15.5 0.1 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 Exostosin family Filament PF00038.21 PRP81355.1 - 0.24 10.9 6.3 0.35 10.4 1.7 2.3 2 0 0 2 2 2 0 Intermediate filament protein Guanylate_cyc PF00211.20 PRP81356.1 - 1.4e-31 109.5 0.0 2.5e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MFS_1 PF07690.16 PRP81357.1 - 2.7e-33 115.4 32.0 4.4e-33 114.7 30.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 PRP81357.1 - 0.0012 17.5 25.8 0.0072 14.9 6.1 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein CBFD_NFYB_HMF PF00808.23 PRP81358.1 - 2.6e-12 46.8 0.0 5.8e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3744 PF12558.8 PRP81358.1 - 0.049 14.4 2.3 0.071 13.9 0.6 2.1 1 1 1 2 2 2 0 ATP-binding cassette cobalt transporter Histone PF00125.24 PRP81358.1 - 0.6 10.5 0.0 0.6 10.5 0.0 3.2 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SET PF00856.28 PRP81359.1 - 1.3e-19 71.2 0.1 1.3e-19 71.2 0.1 3.4 3 2 0 3 3 3 1 SET domain AWS PF17907.1 PRP81359.1 - 1.5e-14 53.7 3.6 1.5e-14 53.7 3.6 1.9 2 0 0 2 2 2 1 AWS domain Ribosomal_L13e PF01294.18 PRP81360.1 - 9.9e-59 198.2 7.7 1.4e-58 197.7 7.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e ING PF12998.7 PRP81360.1 - 0.092 13.3 0.2 0.2 12.3 0.2 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Renin_r PF07850.14 PRP81361.1 - 9.5e-12 45.4 0.0 2.3e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Renin receptor-like protein Phosphodiest PF01663.22 PRP81361.1 - 4e-05 23.4 0.0 8.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase OST_P2 PF18235.1 PRP81361.1 - 0.017 15.0 0.1 0.073 13.0 0.1 2.0 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain V-SNARE_C PF12352.8 PRP81362.1 - 1.2e-12 47.9 1.0 1.2e-12 47.9 1.0 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PRP81362.1 - 0.0055 16.6 0.1 0.026 14.4 0.0 2.1 3 0 0 3 3 3 1 Sec20 MbeB_N PF04837.12 PRP81362.1 - 0.031 14.6 0.2 0.079 13.3 0.2 1.8 1 0 0 1 1 1 0 MbeB-like, N-term conserved region SAS4 PF15460.6 PRP81365.1 - 0.01 15.9 0.3 0.49 10.5 0.1 3.2 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 tRNA-synt_2 PF00152.20 PRP81366.1 - 5e-89 298.5 0.0 6.9e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PRP81366.1 - 3.7e-08 33.2 0.0 7.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PRP81366.1 - 0.00014 21.4 0.1 0.032 13.7 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) PuR_N PF09182.10 PRP81366.1 - 0.075 13.0 0.0 1.5 8.8 0.0 2.8 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Borealin PF10512.9 PRP81369.1 - 0.025 14.6 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 Ank_4 PF13637.6 PRP81370.1 - 1.9e-19 69.8 0.2 0.00022 21.7 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81370.1 - 3.8e-16 59.4 0.4 3.4e-05 24.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP81370.1 - 2.2e-13 50.1 2.5 0.0056 17.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81370.1 - 4.9e-07 29.5 0.2 4.9 8.0 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 PRP81370.1 - 4.5e-05 23.7 5.1 0.92 10.1 0.0 4.8 6 0 0 6 6 6 2 Ankyrin repeat SAM_KSR1 PF13543.6 PRP81370.1 - 0.14 12.3 0.1 3.8 7.6 0.1 2.5 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 ANAPC4_WD40 PF12894.7 PRP81371.1 - 0.0013 19.0 0.4 0.073 13.4 0.1 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 PRP81371.1 - 0.0094 15.3 0.4 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region DUF5427 PF10310.9 PRP81371.1 - 0.029 13.4 12.8 0.049 12.6 12.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) WD40_like PF17005.5 PRP81371.1 - 0.038 13.3 0.0 0.038 13.3 0.0 2.1 3 0 0 3 3 3 0 WD40-like domain RrnaAD PF00398.20 PRP81372.1 - 6.8e-43 146.6 0.0 8.7e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase UPF0113_N PF17833.1 PRP81372.1 - 4.9e-29 100.7 0.1 1e-28 99.7 0.1 1.6 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 PRP81372.1 - 7.5e-16 58.2 0.0 1.8e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 PRP81372.1 - 0.0027 17.6 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 PUA domain PRMT5 PF05185.16 PRP81372.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_28 PF02636.17 PRP81372.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CBF PF03914.17 PRP81373.1 - 1.2e-31 110.0 0.2 2.6e-31 109.0 0.2 1.6 1 0 0 1 1 1 1 CBF/Mak21 family Herpes_UL6 PF01763.16 PRP81373.1 - 0.0029 16.2 0.5 0.29 9.6 0.1 2.3 2 0 0 2 2 2 2 Herpesvirus UL6 like MMS1_N PF10433.9 PRP81374.1 - 5.9e-150 500.1 0.0 8.9e-149 496.2 0.0 2.2 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PRP81374.1 - 2.2e-96 323.0 0.0 1.2e-94 317.2 0.0 2.9 3 0 0 3 3 3 1 CPSF A subunit region RhoGAP PF00620.27 PRP81374.1 - 7e-41 139.6 0.0 1.3e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain EMP70 PF02990.16 PRP81375.1 - 1.4e-201 670.7 12.8 2.5e-201 669.9 12.8 1.4 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 PRP81375.1 - 0.0009 18.3 16.0 0.0009 18.3 16.0 3.4 2 1 1 4 4 4 1 Major Facilitator Superfamily Potyvirid-P3 PF13608.6 PRP81375.1 - 0.087 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Ank_5 PF13857.6 PRP81376.1 - 0.16 12.3 0.0 4.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Not1 PF04054.15 PRP81377.1 - 5.6e-141 469.7 4.9 5.6e-141 469.7 4.9 2.9 2 1 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 PRP81377.1 - 1.8e-85 285.9 6.1 1.5e-83 279.6 1.9 3.8 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 PRP81377.1 - 9.5e-63 210.8 0.4 5.4e-62 208.3 0.0 2.6 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 PRP81377.1 - 1.4e-61 206.7 3.3 5.2e-61 204.9 3.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 PRP81377.1 - 3.7e-28 98.5 0.2 5.2e-27 94.8 0.0 2.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat VWA_2 PF13519.6 PRP81377.1 - 2.9e-13 50.4 0.1 3.8e-12 46.8 0.0 3.1 2 0 0 2 2 2 1 von Willebrand factor type A domain INT_SG_DDX_CT_C PF15300.6 PRP81377.1 - 1.7e-09 37.3 1.3 1e-08 34.8 0.4 2.7 2 0 0 2 2 2 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VWA PF00092.28 PRP81377.1 - 0.00029 21.1 0.8 0.001 19.3 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain FeoB_Cyto PF17910.1 PRP81377.1 - 0.094 13.3 0.1 0.41 11.2 0.1 2.2 1 0 0 1 1 1 0 FeoB cytosolic helical domain CRISPR_Cse2 PF09485.10 PRP81377.1 - 0.31 11.6 1.0 3.4 8.2 0.1 3.2 4 0 0 4 4 4 0 CRISPR-associated protein Cse2 (CRISPR_cse2) TB2_DP1_HVA22 PF03134.19 PRP81378.1 - 1.4e-13 50.6 7.1 1.4e-13 50.6 7.1 2.0 1 1 1 2 2 2 1 TB2/DP1, HVA22 family F-box-like PF12937.7 PRP81379.1 - 1.8e-07 30.9 0.3 7e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like DUF4020 PF13212.6 PRP81379.1 - 0.0026 17.6 0.0 0.0042 16.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4020) Phage_antitermQ PF06530.12 PRP81379.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q F-box_4 PF15966.5 PRP81379.1 - 0.074 12.9 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box F-box PF00646.33 PRP81379.1 - 0.14 12.1 0.8 1 9.3 0.2 2.4 2 0 0 2 2 2 0 F-box domain SHS2_Rpb7-N PF03876.17 PRP81380.1 - 2.6e-08 34.1 0.0 5.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 PRP81380.1 - 4.2e-06 27.4 0.0 6.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I Histone PF00125.24 PRP81381.1 - 2.2e-51 173.6 2.9 3.2e-51 173.1 2.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PRP81381.1 - 0.00021 21.4 0.8 0.0004 20.5 0.1 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PRP81381.1 - 0.00046 20.5 0.1 0.0021 18.4 0.0 2.1 2 0 0 2 2 2 1 CENP-S protein PAF PF15715.5 PRP81381.1 - 0.001 19.7 1.8 0.0017 19.0 1.8 1.3 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 PRP81381.1 - 0.064 13.5 0.0 0.6 10.4 0.1 2.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PRP81381.1 - 0.089 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit IQ PF00612.27 PRP81383.1 - 0.003 17.2 0.1 0.013 15.3 0.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif Acetyltransf_10 PF13673.7 PRP81384.1 - 3.6e-06 26.9 0.0 7.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP81384.1 - 4.9e-05 23.5 0.0 7.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 PRP81384.1 - 0.011 15.8 0.0 0.037 14.1 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP81384.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 PRP81384.1 - 0.045 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 PRP81384.1 - 0.09 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UNC45-central PF11701.8 PRP81384.1 - 0.18 11.7 0.1 0.37 10.7 0.0 1.5 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central RhoGEF PF00621.20 PRP81385.1 - 1.7e-39 136.0 3.0 2.5e-39 135.4 3.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PRP81385.1 - 2.2e-05 24.9 0.1 0.00038 20.9 0.1 2.6 1 1 0 1 1 1 1 PH domain IQ PF00612.27 PRP81385.1 - 5.6e-05 22.6 2.9 0.00018 21.0 2.9 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif PEPcase PF00311.17 PRP81386.1 - 3.9e-05 22.0 3.6 0.00015 20.0 3.6 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxylase MRP-S32 PF10210.9 PRP81386.1 - 0.11 13.1 0.9 0.24 12.0 0.8 1.7 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 SOR_SNZ PF01680.17 PRP81387.1 - 1.3e-108 361.5 5.4 2e-108 360.9 5.4 1.3 1 0 0 1 1 1 1 SOR/SNZ family Ephrin_rec_like PF07699.13 PRP81387.1 - 1.4e-14 53.6 14.8 2.5e-11 43.1 6.9 5.2 4 1 1 5 5 5 2 Putative ephrin-receptor like ThiG PF05690.14 PRP81387.1 - 2.5e-07 30.3 5.0 2.6e-06 26.9 0.4 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DUF3262 PF11660.8 PRP81387.1 - 0.013 15.9 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Dus PF01207.17 PRP81387.1 - 0.021 13.9 0.1 5.7 5.9 0.0 2.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 PRP81387.1 - 0.066 12.7 0.6 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 PRP81387.1 - 0.11 11.6 0.3 0.77 8.9 0.0 2.1 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NTP_transferase PF00483.23 PRP81388.1 - 1.2e-26 93.8 0.0 1.7e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 PRP81388.1 - 1.4e-08 34.1 8.6 3.4e-07 29.7 0.7 3.8 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 PRP81388.1 - 7.7e-05 23.1 0.0 0.00012 22.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 PRP81388.1 - 0.0027 15.9 0.2 0.0036 15.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 PRP81388.1 - 2.4 8.0 7.9 1.3 8.8 1.1 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase SNF5 PF04855.12 PRP81389.1 - 4.7e-39 134.6 9.9 9.2e-39 133.6 5.1 2.8 1 1 1 2 2 2 1 SNF5 / SMARCB1 / INI1 RRP7 PF12923.7 PRP81390.1 - 1.1e-22 80.4 16.0 1.9e-22 79.6 16.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Pex2_Pex12 PF04757.14 PRP81390.1 - 1.7e-20 73.6 0.3 4.3e-20 72.3 0.3 1.7 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region DUF4395 PF14340.6 PRP81390.1 - 2.6e-20 73.1 6.6 2.6e-20 73.1 6.6 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4395) zf-RING_2 PF13639.6 PRP81390.1 - 1.6e-09 37.9 14.3 3.9e-09 36.7 14.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PRP81390.1 - 6.9e-08 32.4 9.1 7.2e-08 32.3 7.3 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP81390.1 - 7.1e-08 32.2 14.2 7.1e-08 32.2 14.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP81390.1 - 5e-07 29.5 9.0 5e-07 29.5 9.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP81390.1 - 1.2e-06 28.3 13.6 1.2e-06 28.3 13.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP81390.1 - 1.7e-05 24.6 9.5 1.7e-05 24.6 9.5 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PRP81390.1 - 1.8e-05 24.8 12.9 1.8e-05 24.8 12.9 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PRP81390.1 - 0.00015 22.0 10.2 0.00037 20.7 10.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PRP81390.1 - 0.00017 21.4 10.9 0.00017 21.4 10.9 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PRP81390.1 - 0.011 15.7 1.5 0.034 14.2 1.5 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 PRP81390.1 - 0.47 10.4 5.0 1.2 9.1 5.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HCBP_related PF06594.11 PRP81392.1 - 0.007 16.3 1.4 7 6.7 0.0 3.2 3 0 0 3 3 3 2 Haemolysin-type calcium binding protein related domain Suppressor_APC PF11414.8 PRP81392.1 - 0.024 14.7 0.4 13 5.9 0.0 3.6 1 1 3 4 4 4 0 Adenomatous polyposis coli tumour suppressor protein JAB PF01398.21 PRP81392.1 - 0.052 13.5 1.6 0.32 11.0 0.1 2.6 1 1 1 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4628 PF15429.6 PRP81392.1 - 0.057 13.1 0.2 0.057 13.1 0.2 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4628) Transcrip_act PF04949.13 PRP81392.1 - 0.27 11.1 1.0 57 3.6 0.0 3.5 1 1 3 4 4 4 0 Transcriptional activator DUF2564 PF10819.8 PRP81392.1 - 2.3 8.7 11.2 57 4.2 0.2 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF2564) BTB PF00651.31 PRP81393.1 - 7.9e-18 64.7 1.8 1.4e-16 60.7 0.0 3.1 3 1 1 4 4 4 1 BTB/POZ domain BACK PF07707.15 PRP81393.1 - 2.4e-15 56.5 3.5 6.5e-13 48.7 1.0 2.4 2 0 0 2 2 2 2 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 PRP81393.1 - 6.3e-05 23.1 0.2 0.00012 22.2 0.2 1.3 1 0 0 1 1 1 1 F5/8 type C domain SH3_9 PF14604.6 PRP81395.1 - 3.5e-24 84.4 0.5 7e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PRP81395.1 - 7.3e-24 83.1 2.0 1.9e-11 43.3 0.0 2.7 2 0 0 2 2 2 2 SH3 domain Methyltransf_11 PF08241.12 PRP81395.1 - 1.6e-19 70.3 0.0 3.7e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP81395.1 - 9.2e-19 68.0 0.0 3.2e-18 66.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain SH3_2 PF07653.17 PRP81395.1 - 2.3e-17 62.4 0.1 1.6e-09 37.3 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Methyltransf_12 PF08242.12 PRP81395.1 - 7.2e-14 52.3 0.0 1.5e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP81395.1 - 1.4e-13 51.0 0.0 2.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP81395.1 - 4.9e-12 46.0 0.0 9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP81395.1 - 4e-11 42.7 0.0 7.9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 PRP81395.1 - 5.5e-08 32.4 0.0 8.9e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 PRP81395.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 PRP81395.1 - 0.00092 18.8 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CENP-Q PF13094.6 PRP81395.1 - 0.0047 17.1 2.7 0.0047 17.1 2.7 2.0 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit RrnaAD PF00398.20 PRP81395.1 - 0.0067 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 PRP81395.1 - 0.014 15.0 0.0 0.085 12.4 0.0 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 PRP81395.1 - 0.019 14.5 0.0 0.067 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_32 PF13679.6 PRP81395.1 - 0.035 14.1 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TSC22 PF01166.18 PRP81395.1 - 0.048 14.0 3.8 1.1 9.6 2.3 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF938 PF06080.12 PRP81395.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) UPF0146 PF03686.13 PRP81395.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Methyltransf_3 PF01596.17 PRP81395.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase ABC_tran_Xtn PF12848.7 PRP81395.1 - 0.12 12.4 1.9 0.31 11.1 1.9 1.7 1 0 0 1 1 1 0 ABC transporter PrmA PF06325.13 PRP81395.1 - 0.14 11.5 0.1 0.57 9.5 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.26 PRP81395.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF4686 PF15742.5 PRP81395.1 - 0.25 10.5 11.5 0.38 9.8 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) bZIP_1 PF00170.21 PRP81395.1 - 0.67 10.1 3.6 0.92 9.6 2.4 1.9 2 0 0 2 2 1 0 bZIP transcription factor ATG16 PF08614.11 PRP81395.1 - 0.69 10.1 13.1 1.4 9.1 12.8 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4763 PF15960.5 PRP81395.1 - 3.5 6.8 8.6 1.2 8.4 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Lebercilin PF15619.6 PRP81395.1 - 4.1 7.0 14.7 1.6 8.4 6.9 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HrpB7 PF09486.10 PRP81395.1 - 7.7 6.9 10.2 2.4 8.5 5.4 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF3040 PF11239.8 PRP81396.1 - 0.041 14.2 1.2 0.041 14.2 1.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3040) Otopetrin PF03189.13 PRP81396.1 - 0.13 11.0 4.4 0.17 10.7 4.4 1.2 1 0 0 1 1 1 0 Otopetrin DUF1772 PF08592.11 PRP81396.1 - 0.14 12.5 6.6 0.12 12.6 4.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Tetraspanin PF00335.20 PRP81396.1 - 0.92 9.2 14.3 0.023 14.4 4.3 2.5 1 1 1 2 2 2 0 Tetraspanin family DUF3810 PF12725.7 PRP81396.1 - 2.4 7.4 4.4 4.1 6.7 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Trp_oprn_chp PF09534.10 PRP81396.1 - 3.5 7.4 10.7 2.4 7.9 3.9 2.3 1 1 2 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) START PF01852.19 PRP81397.1 - 1.1e-05 25.0 2.3 0.012 15.1 0.1 2.7 3 0 0 3 3 3 2 START domain Acyltransf_C PF16076.5 PRP81397.1 - 4.5e-05 23.4 4.4 0.07 13.2 0.0 3.5 3 0 0 3 3 3 2 Acyltransferase C-terminus NPA PF16469.5 PRP81397.1 - 0.9 10.1 14.1 2.8 8.5 2.5 2.9 2 1 0 2 2 2 0 Nematode polyprotein allergen ABA-1 LRR_4 PF12799.7 PRP81398.1 - 3.8e-09 36.7 8.1 0.00037 20.8 0.1 5.3 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP81398.1 - 0.0053 17.1 6.8 52 5.0 0.0 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat DBC1 PF14443.6 PRP81398.1 - 0.012 15.5 1.9 1.8 8.6 0.0 3.4 3 1 1 4 4 4 0 DBC1 LRR_6 PF13516.6 PRP81398.1 - 0.017 15.2 13.4 3.5 7.9 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich repeat LRR_8 PF13855.6 PRP81398.1 - 1.7 8.5 7.2 40 4.1 0.0 4.6 3 1 2 5 5 5 0 Leucine rich repeat Dicty_CAR PF05462.11 PRP81399.1 - 2.7e-21 76.0 14.8 3.6e-21 75.6 14.8 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 PRP81399.1 - 1.2e-10 41.2 14.7 1.4e-10 40.9 14.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 PRP81399.1 - 1.4e-05 24.5 11.4 7.4e-05 22.2 11.4 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 PRP81399.1 - 0.00047 19.3 18.4 0.11 11.5 18.4 2.5 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region Ocular_alb PF02101.15 PRP81399.1 - 0.018 14.0 12.5 0.041 12.8 12.5 1.6 1 1 0 1 1 1 0 Ocular albinism type 1 protein GPR_Gpa2_C PF11970.8 PRP81399.1 - 0.18 11.9 0.1 0.18 11.9 0.1 2.7 2 1 1 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Wzy_C PF04932.15 PRP81399.1 - 0.55 9.9 4.6 5.8 6.5 1.1 2.3 2 0 0 2 2 2 0 O-Antigen ligase GATA PF00320.27 PRP81400.1 - 5.7e-14 51.4 4.1 5.7e-14 51.4 4.1 2.2 2 0 0 2 2 2 1 GATA zinc finger F-box-like PF12937.7 PRP81400.1 - 1.1e-06 28.4 0.6 3.4e-06 26.8 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP81400.1 - 2.1e-06 27.4 0.2 7.5e-06 25.7 0.2 2.0 2 0 0 2 2 2 1 F-box domain Copine PF07002.16 PRP81401.1 - 2.2e-52 177.7 0.0 3.3e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 PRP81401.1 - 2.7e-21 75.8 0.0 1.6e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 PRP81401.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus PH PF00169.29 PRP81402.1 - 0.0018 18.8 0.1 0.0066 16.9 0.0 2.0 2 0 0 2 2 2 1 PH domain Herpes_UL52 PF03121.15 PRP81403.1 - 2.8e-10 40.0 0.3 5.4e-10 39.1 0.3 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase COX2 PF00116.20 PRP81403.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain Antimicrobial_5 PF08026.11 PRP81403.1 - 1.3 9.2 5.3 0.23 11.6 0.5 2.2 2 0 0 2 2 2 0 Bee antimicrobial peptide Arrestin_C PF02752.22 PRP81404.1 - 1.4e-16 61.2 0.0 2.1e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PRP81404.1 - 1.8e-07 31.3 0.0 0.0078 16.3 0.0 3.6 2 2 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF11 PF01345.18 PRP81404.1 - 0.00037 20.7 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF11 MG2 PF01835.19 PRP81404.1 - 0.01 16.3 0.1 0.76 10.3 0.0 2.7 2 1 1 3 3 3 0 MG2 domain A2M_BRD PF07703.14 PRP81404.1 - 0.017 15.4 0.0 2.3 8.6 0.0 2.4 1 1 1 2 2 2 0 Alpha-2-macroglobulin bait region domain Glyco_hydro_66 PF13199.6 PRP81404.1 - 0.03 13.0 0.0 3.8 6.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 66 Rgp1 PF08737.10 PRP81404.1 - 0.041 13.1 0.0 6.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Rgp1 Pox_RNA_pol PF03293.14 PRP81404.1 - 0.1 12.3 0.0 0.39 10.4 0.1 1.8 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit Cohesin PF00963.18 PRP81404.1 - 0.14 12.4 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Cohesin domain Pkinase_Tyr PF07714.17 PRP81405.1 - 6.3e-69 232.1 0.0 8.9e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81405.1 - 1.2e-45 156.0 0.0 1.7e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 PRP81405.1 - 0.00026 21.0 15.6 0.0015 18.6 5.0 8.1 7 3 2 9 9 9 2 IPT/TIG domain LRR_4 PF12799.7 PRP81405.1 - 0.00073 19.9 7.9 0.06 13.8 0.2 3.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Chlam_PMP PF02415.17 PRP81405.1 - 0.026 15.0 0.6 0.026 15.0 0.6 24.4 22 4 0 22 22 22 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Syndecan PF01034.20 PRP81405.1 - 0.42 10.6 1.1 0.92 9.5 1.1 1.5 1 0 0 1 1 1 0 Syndecan domain LRR_8 PF13855.6 PRP81405.1 - 0.46 10.3 17.4 0.053 13.3 6.5 3.8 3 1 1 4 4 4 0 Leucine rich repeat Inhibitor_I68 PF10468.9 PRP81406.1 - 0.069 13.6 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 zf-C3HC4_3 PF13920.6 PRP81407.1 - 6.6e-08 32.3 6.7 1.1e-07 31.5 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF812 PF05667.11 PRP81407.1 - 0.0019 17.2 12.3 0.0024 16.9 12.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_13 PF13166.6 PRP81407.1 - 0.0045 15.7 9.9 0.0054 15.4 9.9 1.2 1 0 0 1 1 1 1 AAA domain Prok-RING_4 PF14447.6 PRP81407.1 - 0.0056 16.5 7.4 0.01 15.7 7.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PRP81407.1 - 0.0078 16.1 5.9 0.019 14.9 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP81407.1 - 0.013 15.3 6.6 0.027 14.3 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 PRP81407.1 - 0.046 13.1 5.6 0.081 12.3 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 PRP81407.1 - 0.097 12.8 22.4 0.077 13.1 11.2 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 PRP81407.1 - 0.12 12.6 21.6 0.061 13.5 4.3 2.4 2 1 0 2 2 2 0 Tropomyosin like SidE PF12252.8 PRP81407.1 - 0.12 9.9 9.1 0.15 9.5 9.1 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein zf-RING_14 PF17978.1 PRP81407.1 - 0.18 12.2 4.2 0.38 11.2 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Spc7 PF08317.11 PRP81407.1 - 0.23 10.3 18.2 0.45 9.4 18.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 PRP81407.1 - 0.28 11.4 11.0 0.99 9.7 10.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) GAS PF13851.6 PRP81407.1 - 0.43 9.9 22.0 1.4 8.3 8.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 PRP81407.1 - 0.66 9.8 15.3 4.3 7.2 0.8 3.5 1 1 2 3 3 3 0 Septum formation initiator DUF4446 PF14584.6 PRP81407.1 - 0.74 9.8 9.1 0.24 11.4 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) FUSC PF04632.12 PRP81407.1 - 0.96 7.9 5.7 1.4 7.4 5.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4200 PF13863.6 PRP81407.1 - 1.1 9.6 19.4 5 7.6 11.1 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) SpecificRecomb PF10136.9 PRP81407.1 - 1.7 6.9 10.7 1.3 7.2 9.4 1.4 1 1 0 1 1 1 0 Site-specific recombinase APG6_N PF17675.1 PRP81407.1 - 2 9.0 24.0 2.6 8.6 13.8 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 PRP81407.1 - 3.6 7.6 12.3 7.3 6.7 3.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 PRP81407.1 - 4.1 7.8 12.0 16 5.9 4.4 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 PRP81407.1 - 4.4 8.0 17.4 19 6.0 7.8 2.8 1 1 1 2 2 2 0 Initiation control protein YabA betaPIX_CC PF16523.5 PRP81407.1 - 5.7 6.8 13.2 0.99 9.3 7.2 2.4 2 0 0 2 2 2 0 betaPIX coiled coil BRE1 PF08647.11 PRP81407.1 - 5.8 7.1 20.3 1.7 8.8 8.1 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase TMF_TATA_bd PF12325.8 PRP81407.1 - 5.8 7.2 23.6 0.89 9.8 13.2 2.6 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding DUF1216 PF06746.11 PRP81407.1 - 8.4 6.4 13.5 0.87 9.6 1.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1216) DUF719 PF05334.13 PRP81408.1 - 0.036 14.3 0.0 0.036 14.3 0.0 5.3 3 1 2 5 5 5 0 Protein of unknown function (DUF719) Acyl-CoA_dh_C PF12806.7 PRP81408.1 - 2 8.6 5.1 21 5.3 1.8 2.8 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Rad51 PF08423.11 PRP81409.1 - 7.6e-07 28.6 0.2 3.3e-06 26.6 0.0 2.0 2 1 0 2 2 2 1 Rad51 IQ PF00612.27 PRP81409.1 - 0.00065 19.3 0.0 0.0018 17.9 0.0 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif FAD-oxidase_C PF02913.19 PRP81410.1 - 5e-56 190.1 0.0 6.6e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PRP81410.1 - 9.1e-38 129.1 1.2 1.5e-37 128.5 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain PIN_5 PF08745.11 PRP81410.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PINc domain ribonuclease N6_N4_Mtase PF01555.18 PRP81411.1 - 0.00083 19.1 0.5 0.0031 17.2 0.1 2.0 2 0 0 2 2 2 1 DNA methylase Methyltransf_23 PF13489.6 PRP81411.1 - 0.069 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Phage_spike_2 PF18781.1 PRP81411.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.6 1 1 0 1 1 1 0 Phage spike trimer HATPase_c PF02518.26 PRP81412.1 - 2e-31 108.8 0.0 5.1e-31 107.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP81412.1 - 2.4e-14 53.5 0.8 4.7e-12 46.1 0.5 3.4 3 1 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 PRP81412.1 - 0.00012 22.1 0.0 0.0019 18.2 0.0 3.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain FleQ PF06490.11 PRP81412.1 - 0.00099 19.5 0.0 0.0038 17.6 0.0 2.0 1 0 0 1 1 1 1 Flagellar regulatory protein FleQ HATPase_c_5 PF14501.6 PRP81412.1 - 0.0071 16.2 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 GHKL domain HATPase_c_2 PF13581.6 PRP81412.1 - 0.073 13.0 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Acetyltransf_9 PF13527.7 PRP81414.1 - 2.7e-16 59.8 0.0 4.5e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP81414.1 - 3.8e-06 27.1 0.0 1.1e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP81414.1 - 6.8e-06 26.0 0.0 1.6e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP81414.1 - 0.00046 20.6 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP81414.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein DUF4690 PF15756.5 PRP81415.1 - 1.7e-05 25.3 0.5 1.7e-05 25.3 0.5 2.0 2 0 0 2 2 2 1 Small Novel Rich in Cartilage EGF_2 PF07974.13 PRP81415.1 - 0.031 14.7 9.9 0.056 13.8 9.9 1.5 1 0 0 1 1 1 0 EGF-like domain CWC25 PF12542.8 PRP81416.1 - 2e-13 51.1 0.6 2e-13 51.1 0.6 3.5 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 PRP81416.1 - 2.9e-11 43.4 2.9 2.9e-11 43.4 2.9 5.6 4 2 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR BING4CT PF08149.11 PRP81416.1 - 2.8 7.8 9.5 0.13 12.1 0.6 3.0 2 2 1 3 3 3 0 BING4CT (NUC141) domain Tht1 PF04163.12 PRP81417.1 - 0.061 12.1 0.1 0.066 12.0 0.1 1.0 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Peptidase_M24_C PF16188.5 PRP81417.1 - 0.083 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of peptidase_M24 Ammonium_transp PF00909.21 PRP81418.1 - 1.1e-102 343.8 27.2 1.4e-102 343.4 27.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DOMON PF03351.17 PRP81419.1 - 2.2e-52 176.5 12.9 6.6e-28 97.4 1.9 2.7 2 0 0 2 2 2 2 DOMON domain Ferric_reduct PF01794.19 PRP81419.1 - 9.9e-19 67.7 11.5 9.9e-19 67.7 11.5 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 PRP81419.1 - 7.2e-15 55.0 0.0 1.7e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 PRP81419.1 - 7.7e-15 55.3 0.1 7.5e-13 48.9 0.1 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain CDH-cyt PF16010.5 PRP81419.1 - 8.5e-08 32.1 6.6 0.00026 20.7 0.9 2.8 2 1 0 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase NAD_binding_1 PF00175.21 PRP81419.1 - 2.3e-06 28.2 0.0 5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PRP81419.1 - 0.031 14.6 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Glyco_hydro_15 PF00723.21 PRP81420.1 - 1.9e-50 172.0 0.0 2.6e-49 168.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TRH PF05438.12 PRP81420.1 - 0.1 12.3 2.0 3 7.5 0.1 2.1 2 0 0 2 2 2 0 Thyrotropin-releasing hormone (TRH) SHR-BD PF06650.12 PRP81422.1 - 4.9e-51 173.7 4.6 3.3e-48 164.4 3.4 2.6 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 PRP81422.1 - 3.6e-49 167.7 9.6 1.7e-32 113.1 0.4 4.2 2 1 1 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 PRP81422.1 - 5.1e-29 100.7 1.1 5.6e-28 97.4 1.1 3.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 PRP81422.1 - 7.1e-22 78.0 6.4 2.4e-17 63.3 0.0 3.8 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 PRP81422.1 - 2.7e-19 69.5 21.9 4.6e-18 65.5 1.4 6.0 5 1 0 5 5 5 2 Repeating coiled region of VPS13 C2 PF00168.30 PRP81422.1 - 1.1e-09 38.5 0.0 6.9e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 C2 domain DUF2209 PF09974.9 PRP81423.1 - 0.044 14.1 1.4 6.8 7.1 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) Chlorosome_CsmC PF11098.8 PRP81423.1 - 4.3 7.3 15.2 0.68 9.9 6.8 2.8 1 1 1 2 2 2 0 Chlorosome envelope protein C GTP_EFTU PF00009.27 PRP81425.1 - 1.6e-49 168.1 0.8 2.1e-49 167.7 0.8 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PRP81425.1 - 2.8e-40 137.1 0.0 6.6e-40 135.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PRP81425.1 - 2.6e-13 50.1 0.4 7e-13 48.8 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PRP81425.1 - 5.3e-05 23.3 0.1 0.0022 18.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP81425.1 - 0.0047 16.3 0.0 0.011 15.0 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU_D4 PF14578.6 PRP81425.1 - 0.015 15.2 1.6 0.022 14.7 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 UvrD-helicase PF00580.21 PRP81426.1 - 2.1e-31 109.6 6.6 1.1e-27 97.4 3.8 3.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PRP81426.1 - 2.7e-29 102.6 0.0 1.2e-26 94.0 0.0 3.0 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PRP81426.1 - 1.7e-17 64.1 0.0 3.5e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 PRP81426.1 - 8.9e-12 45.4 3.5 6.3e-10 39.4 0.1 3.2 2 1 1 3 3 3 2 PD-(D/E)XK nuclease superfamily UvrD_C_2 PF13538.6 PRP81426.1 - 2.5e-11 43.2 0.1 0.00025 20.8 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain APH PF01636.23 PRP81426.1 - 3.2e-07 30.5 0.1 1.7e-06 28.1 0.0 2.3 3 0 0 3 3 3 1 Phosphotransferase enzyme family AAA_12 PF13087.6 PRP81426.1 - 3.1e-05 23.7 0.3 0.0031 17.2 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.6 PRP81426.1 - 0.00038 20.2 0.0 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PRP81426.1 - 0.064 13.0 0.8 0.32 10.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain PFU PF09070.11 PRP81426.1 - 0.34 11.2 0.0 0.34 11.2 0.0 2.3 3 0 0 3 3 2 0 PFU (PLAA family ubiquitin binding) Viral_helicase1 PF01443.18 PRP81426.1 - 0.42 10.3 2.3 12 5.5 0.0 3.9 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase Pkinase_Tyr PF07714.17 PRP81428.1 - 3.3e-75 252.7 0.3 4.4e-75 252.3 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81428.1 - 1.9e-53 181.5 0.1 2.9e-53 180.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP81428.1 - 9.1e-33 111.8 97.2 4.8e-09 35.8 4.0 12.9 8 3 6 14 14 14 11 Leucine rich repeat LRR_4 PF12799.7 PRP81428.1 - 2.2e-29 101.0 110.5 3e-05 24.3 2.8 16.8 9 5 7 17 17 17 14 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP81428.1 - 0.00024 20.9 67.7 1.2 9.3 0.2 17.4 19 0 0 19 19 19 3 Leucine Rich repeat Kinase-like PF14531.6 PRP81428.1 - 0.00084 18.7 0.1 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PRP81428.1 - 0.0019 17.0 0.1 0.0031 16.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP81428.1 - 0.0035 16.3 1.9 0.0077 15.2 1.9 1.5 1 0 0 1 1 1 1 Haspin like kinase domain LRR_1 PF00560.33 PRP81428.1 - 0.011 16.1 94.4 0.058 14.0 2.1 22.9 23 2 1 24 24 22 0 Leucine Rich Repeat Kdo PF06293.14 PRP81428.1 - 0.014 14.8 0.2 0.024 14.0 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family stn_TNFRSF12A PF12191.8 PRP81428.1 - 0.021 15.0 0.1 0.053 13.7 0.0 1.6 2 0 0 2 2 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LRRNT_2 PF08263.12 PRP81428.1 - 0.13 12.6 0.7 0.39 11.1 0.7 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain DUF2201_N PF13203.6 PRP81429.1 - 6.2e-05 22.7 0.5 0.00016 21.4 0.5 1.7 1 1 0 1 1 1 1 Putative metallopeptidase domain CRT10 PF08728.10 PRP81429.1 - 9.7 4.2 14.4 14 3.7 14.4 1.3 1 0 0 1 1 1 0 CRT10 Toxin_36 PF10550.9 PRP81430.1 - 0.22 12.9 0.9 30 6.3 0.0 3.0 3 0 0 3 3 3 0 Conantokin-G mollusc-toxin Pkinase_Tyr PF07714.17 PRP81431.1 - 2.1e-52 178.0 0.0 5.1e-52 176.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81431.1 - 4.4e-48 163.9 0.0 8.9e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 PRP81431.1 - 1.2e-30 105.9 7.4 1.4e-12 48.0 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 PRP81431.1 - 9e-19 67.0 1.1 0.00018 21.8 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 PRP81431.1 - 1.7e-18 66.7 4.0 6.8e-05 23.3 0.1 4.8 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81431.1 - 1.7e-17 61.7 1.3 0.00057 20.1 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PRP81431.1 - 9.4e-15 54.5 1.3 1.9e-06 28.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) C2 PF00168.30 PRP81431.1 - 2.1e-13 50.4 0.1 1.3e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 C2 domain GRAM PF02893.20 PRP81431.1 - 4.6e-08 32.9 0.2 1.2e-07 31.6 0.2 1.6 1 0 0 1 1 1 1 GRAM domain SAM_1 PF00536.30 PRP81431.1 - 2.3e-06 27.9 0.2 1.5e-05 25.4 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP81431.1 - 0.0012 18.9 0.1 0.0031 17.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 PRP81431.1 - 0.002 17.2 0.6 0.002 17.2 0.6 2.9 3 1 0 3 3 3 1 Haspin like kinase domain Kinase-like PF14531.6 PRP81431.1 - 0.0051 16.2 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 PRP81431.1 - 0.033 13.8 0.3 0.21 11.2 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PRP81431.1 - 0.037 13.9 0.2 0.077 12.9 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family G8 PF10162.9 PRP81432.1 - 7.7e-21 74.4 0.3 2e-20 73.1 0.3 1.8 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP81432.1 - 0.00041 20.2 2.2 0.00041 20.2 2.2 3.3 2 2 0 2 2 2 1 Right handed beta helix region HSP70 PF00012.20 PRP81434.1 - 2e-94 317.0 8.3 2e-94 317.0 8.3 2.4 2 1 0 2 2 2 1 Hsp70 protein Hydantoinase_A PF01968.18 PRP81434.1 - 0.00052 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase MreB_Mbl PF06723.13 PRP81434.1 - 0.0018 17.2 0.5 0.02 13.7 0.0 2.7 3 1 0 3 3 3 1 MreB/Mbl protein DUF948 PF06103.11 PRP81434.1 - 0.094 13.0 0.6 0.39 11.0 0.6 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SDA1 PF05285.12 PRP81435.1 - 2.7e-05 23.8 24.0 2.7e-05 23.8 24.0 2.2 2 0 0 2 2 2 1 SDA1 F-box PF00646.33 PRP81435.1 - 0.032 14.1 0.0 43 4.1 0.0 3.9 3 1 0 3 3 3 0 F-box domain GAGA_bind PF06217.12 PRP81435.1 - 0.96 9.7 26.5 1.7 8.9 8.4 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family DDHD PF02862.17 PRP81435.1 - 1.1 9.4 15.0 4.7 7.3 6.4 2.5 2 0 0 2 2 2 0 DDHD domain CDC45 PF02724.14 PRP81435.1 - 5 5.3 53.4 0.02 13.2 27.3 2.1 2 0 0 2 2 2 0 CDC45-like protein p450 PF00067.22 PRP81436.1 - 1.1e-58 199.2 0.4 1.4e-36 126.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF1682 PF07946.14 PRP81437.1 - 0.0057 15.9 15.7 0.011 15.0 15.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) CDC45 PF02724.14 PRP81437.1 - 0.53 8.5 17.7 0.7 8.1 17.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SLX9 PF15341.6 PRP81437.1 - 0.78 10.1 19.0 1.4 9.4 19.0 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DDHD PF02862.17 PRP81437.1 - 0.93 9.6 7.0 1.5 8.9 7.0 1.3 1 0 0 1 1 1 0 DDHD domain XRN_M PF17846.1 PRP81437.1 - 2.6 6.9 10.0 5.2 5.9 10.0 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Afi1 PF07792.12 PRP81437.1 - 7.6 7.0 7.9 16 6.0 7.9 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Merozoite_SPAM PF07133.11 PRP81437.1 - 9.3 6.2 30.2 16 5.4 30.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) MORN PF02493.20 PRP81438.1 - 3.4e-09 36.0 4.0 0.0017 18.1 0.7 3.8 4 0 0 4 4 4 2 MORN repeat CH PF00307.31 PRP81439.1 - 3.6e-11 43.2 0.0 3.8e-07 30.3 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain Ribonuclease_T2 PF00445.18 PRP81440.1 - 1.3e-43 149.4 0.3 1.7e-43 149.0 0.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family IMPDH PF00478.25 PRP81444.1 - 2e-64 217.8 0.0 2.5e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 PRP81444.1 - 1.1e-08 35.4 0.0 0.002 18.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain adh_short PF00106.25 PRP81444.1 - 0.1 12.1 0.1 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase RRM_1 PF00076.22 PRP81445.1 - 1e-24 86.1 0.4 3.1e-12 46.1 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP81445.1 - 1.1e-08 34.7 0.4 0.002 17.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN2_C PF18004.1 PRP81445.1 - 0.0073 16.2 3.7 0.015 15.3 3.7 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain U79_P34 PF03064.16 PRP81445.1 - 0.016 14.6 3.0 0.029 13.7 3.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Diphtheria_T PF02764.14 PRP81445.1 - 0.032 14.3 1.1 0.078 13.0 1.1 1.6 1 0 0 1 1 1 0 Diphtheria toxin, T domain DUF4523 PF15023.6 PRP81445.1 - 0.072 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 PRP81445.1 - 0.12 12.2 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1027 PF06265.11 PRP81445.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) Gly-zipper_YMGG PF13441.6 PRP81445.1 - 1.3 8.8 18.8 0.035 13.8 12.3 1.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 PRP81445.1 - 4.1 7.5 20.7 3.6 7.7 19.1 1.7 1 1 1 2 2 2 0 Glycine zipper GAGA_bind PF06217.12 PRP81445.1 - 6.8 6.9 9.6 6 7.1 7.9 1.6 1 1 0 2 2 2 0 GAGA binding protein-like family Ank_2 PF12796.7 PRP81446.1 - 1.3e-38 131.4 2.9 9.8e-07 29.3 0.0 7.8 3 2 9 12 12 12 10 Ankyrin repeats (3 copies) WD40 PF00400.32 PRP81446.1 - 1.7e-38 129.9 19.5 1.6e-05 25.6 0.0 12.3 12 0 0 12 12 12 6 WD domain, G-beta repeat Epimerase PF01370.21 PRP81446.1 - 1.4e-37 129.5 0.0 5.1e-37 127.6 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PRP81446.1 - 2.2e-29 102.4 0.4 1e-28 100.1 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PRP81446.1 - 4.5e-28 98.6 0.0 1.3e-27 97.1 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Ank_4 PF13637.6 PRP81446.1 - 2.5e-26 91.7 6.7 3.7e-05 24.2 0.0 9.7 6 1 4 11 11 10 5 Ankyrin repeats (many copies) NAD_binding_10 PF13460.6 PRP81446.1 - 4.9e-22 78.7 2.3 1.7e-21 77.0 0.0 3.0 3 0 0 3 3 3 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 PRP81446.1 - 9.7e-21 74.1 0.0 2e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Ank_3 PF13606.6 PRP81446.1 - 1.9e-18 64.6 14.5 0.19 12.4 0.0 13.4 13 0 0 13 13 13 3 Ankyrin repeat NAD_binding_4 PF07993.12 PRP81446.1 - 2.9e-18 66.0 0.0 1.5e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein ANAPC4_WD40 PF12894.7 PRP81446.1 - 3.8e-16 59.1 0.1 0.0087 16.3 0.0 6.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ank_5 PF13857.6 PRP81446.1 - 5e-14 52.2 12.0 1.3 9.4 0.0 11.7 6 2 5 12 12 12 4 Ankyrin repeats (many copies) NmrA PF05368.13 PRP81446.1 - 7.1e-13 48.7 0.4 4e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Ank PF00023.30 PRP81446.1 - 4e-11 42.9 18.7 16 6.1 0.0 13.4 12 2 1 13 13 13 0 Ankyrin repeat Polysacc_synt_2 PF02719.15 PRP81446.1 - 9.6e-09 34.8 0.0 2.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein eIF2A PF08662.11 PRP81446.1 - 5e-06 26.5 0.2 0.19 11.6 0.0 3.5 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PRP81446.1 - 0.00019 21.3 0.5 6.6 6.8 0.0 4.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF1843 PF08898.10 PRP81446.1 - 0.0005 20.5 0.8 5.5 7.6 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1843) DapB_N PF01113.20 PRP81446.1 - 0.0013 18.9 0.1 0.0036 17.4 0.1 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Nup160 PF11715.8 PRP81446.1 - 0.0031 16.2 0.2 0.011 14.4 0.0 1.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PRP81446.1 - 0.014 14.4 0.4 7.4 5.4 0.2 4.0 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2576 PF10845.8 PRP81446.1 - 1.7 8.3 5.3 0.73 9.5 0.1 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF2576) DIL PF01843.19 PRP81448.1 - 6.9e-20 71.3 0.1 6.9e-20 71.3 0.1 2.6 2 0 0 2 2 2 1 DIL domain NT-C2 PF10358.9 PRP81448.1 - 1e-14 54.5 3.9 1e-14 54.5 3.9 2.1 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Spc7 PF08317.11 PRP81448.1 - 0.0016 17.4 108.3 0.0016 17.4 36.5 5.4 1 1 4 5 5 5 4 Spc7 kinetochore protein XhlA PF10779.9 PRP81448.1 - 0.018 15.3 3.7 0.018 15.3 3.7 8.7 6 3 2 8 8 8 0 Haemolysin XhlA Golgin_A5 PF09787.9 PRP81448.1 - 0.026 14.0 103.9 0.014 14.9 34.5 4.8 2 1 3 5 5 5 0 Golgin subfamily A member 5 DUF4407 PF14362.6 PRP81448.1 - 1.2 8.4 77.4 0.31 10.4 21.9 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4407) GAS PF13851.6 PRP81448.1 - 3.2 7.0 115.1 0.15 11.4 30.4 6.5 2 1 3 6 6 6 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 PRP81448.1 - 9.9 4.7 87.2 0.18 10.4 17.0 4.0 1 1 0 3 3 3 0 AAA domain tRNA-synt_2b PF00587.25 PRP81449.1 - 6.7e-43 146.7 0.0 1e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PRP81449.1 - 1.3e-21 76.5 0.2 2.7e-21 75.5 0.2 1.5 1 0 0 1 1 1 1 Anticodon binding domain zinc_ribbon_12 PF11331.8 PRP81450.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain FixP_N PF14715.6 PRP81451.1 - 0.1 12.4 1.6 0.12 12.1 0.2 1.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Dus PF01207.17 PRP81452.1 - 5.1e-34 117.8 0.2 1e-33 116.7 0.2 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NanE PF04131.14 PRP81452.1 - 0.14 11.3 0.0 0.32 10.2 0.0 1.8 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DOCK-C2 PF14429.6 PRP81452.1 - 0.23 11.2 2.4 5.2 6.8 0.2 2.3 2 1 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins EamA PF00892.20 PRP81456.1 - 5.2e-12 46.1 44.6 7.9e-07 29.3 16.4 2.8 3 0 0 3 3 3 2 EamA-like transporter family Ank_2 PF12796.7 PRP81457.1 - 5.1e-27 94.3 0.1 7.2e-09 36.1 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81457.1 - 2.7e-18 66.1 4.5 0.0041 17.7 0.1 7.6 4 2 4 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81457.1 - 3.8e-15 54.5 5.9 0.27 11.9 0.1 9.6 11 0 0 11 11 11 4 Ankyrin repeat Ank PF00023.30 PRP81457.1 - 4.4e-10 39.6 12.9 0.13 12.7 0.1 9.1 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 PRP81457.1 - 9.3e-10 38.6 10.6 1.6 9.1 0.1 8.7 4 1 5 10 10 10 5 Ankyrin repeats (many copies) Peptidase_S74 PF13884.6 PRP81458.1 - 1.8e-17 63.4 0.1 1.6e-16 60.3 0.0 2.5 2 0 0 2 2 2 1 Chaperone of endosialidase DUF2207 PF09972.9 PRP81458.1 - 0.0081 15.0 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 PRP81458.1 - 0.091 13.0 5.4 0.4 11.0 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3784 PF12650.7 PRP81458.1 - 0.19 11.9 1.0 0.37 11.0 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Pkinase PF00069.25 PRP81460.1 - 5.9e-79 265.1 0.0 1.4e-78 263.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81460.1 - 2.1e-37 128.8 0.0 4.1e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.28 PRP81460.1 - 3.7e-15 55.2 0.7 7.9e-15 54.2 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 PRP81460.1 - 1.3e-12 47.3 0.0 3e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP81460.1 - 4.7e-11 42.2 0.0 9.9e-11 41.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 PRP81460.1 - 3.1e-09 36.7 5.4 3.1e-09 36.7 5.4 1.9 2 0 0 2 2 2 1 WW domain Kinase-like PF14531.6 PRP81460.1 - 2.2e-05 24.0 0.0 0.00066 19.1 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP81460.1 - 0.0027 17.1 0.0 0.0027 17.1 0.0 2.4 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3104 PF11302.8 PRP81460.1 - 0.042 13.6 0.2 0.88 9.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) PI_PP_I PF18363.1 PRP81460.1 - 0.046 13.9 2.6 0.55 10.5 0.3 3.3 2 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain Phasin PF05597.11 PRP81460.1 - 0.88 9.6 5.7 5.5 7.0 0.0 2.9 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YlqD PF11068.8 PRP81460.1 - 1.3 9.4 7.6 2.6 8.4 0.7 2.5 2 0 0 2 2 2 0 YlqD protein Nup54 PF13874.6 PRP81460.1 - 2.9 8.0 7.4 7.3 6.7 6.0 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 PRKCSH-like PF12999.7 PRP81460.1 - 5.5 6.8 5.4 17 5.2 0.7 2.4 2 0 0 2 2 2 0 Glucosidase II beta subunit-like GrpE PF01025.19 PRP81460.1 - 9 5.9 11.8 1.6 8.3 3.9 3.1 2 1 0 2 2 2 0 GrpE Peptidase_C14 PF00656.22 PRP81461.1 - 0.028 14.4 0.0 0.038 13.9 0.0 1.3 1 1 0 1 1 1 0 Caspase domain DUF2654 PF10849.8 PRP81461.1 - 0.029 14.6 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) DNA_ligase_OB_2 PF14743.6 PRP81462.1 - 1.4e-26 92.3 0.0 2.7e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 PRP81462.1 - 1.6e-08 34.5 0.0 7.3e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain FecR PF04773.13 PRP81462.1 - 0.042 14.5 0.0 0.086 13.5 0.0 1.6 1 0 0 1 1 1 0 FecR protein CAT_RBD PF03123.15 PRP81462.1 - 0.088 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 CAT RNA binding domain FHA_2 PF17913.1 PRP81462.1 - 0.12 12.6 0.2 0.3 11.3 0.1 1.6 1 1 0 1 1 1 0 FHA domain LRR_8 PF13855.6 PRP81463.1 - 1.9e-62 206.9 115.4 1.2e-08 34.6 2.3 16.7 10 4 6 17 17 17 14 Leucine rich repeat LRR_4 PF12799.7 PRP81463.1 - 2.4e-43 145.4 126.7 2.5e-05 24.5 0.4 19.4 13 4 5 19 19 19 17 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP81463.1 - 1e-14 54.5 0.1 2.4e-14 53.2 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81463.1 - 1.3e-09 37.9 0.1 3.2e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain LRR_1 PF00560.33 PRP81463.1 - 8.3e-05 22.6 118.8 4.1 8.3 0.2 27.8 27 3 0 27 27 27 3 Leucine Rich Repeat GPS PF01825.21 PRP81463.1 - 0.012 16.1 1.2 0.036 14.6 1.2 1.9 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif DUF296 PF03479.15 PRP81463.1 - 0.03 14.7 1.2 2.9e+02 1.9 0.0 6.0 4 3 1 5 5 5 0 Plants and Prokaryotes Conserved (PCC) domain ROF PF07073.12 PRP81463.1 - 0.057 13.6 0.0 4.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Modulator of Rho-dependent transcription termination (ROF) Leader_CPA1 PF08252.11 PRP81463.1 - 0.072 12.5 4.3 5.3 6.5 0.3 2.7 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide DUF3809 PF12723.7 PRP81463.1 - 0.091 13.1 0.0 36 4.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3809) DUF5612 PF18462.1 PRP81463.1 - 0.14 11.9 0.0 30 4.4 0.0 4.1 4 1 2 6 6 6 0 Domain of unknown function (DUF5612) Ank_2 PF12796.7 PRP81464.1 - 7.5e-11 42.5 0.0 6e-05 23.6 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81464.1 - 6.2e-06 26.7 0.1 0.033 14.8 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP81464.1 - 7e-05 23.0 0.5 9.2 6.7 0.0 4.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81464.1 - 0.001 19.4 0.2 15 6.5 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat F-box-like PF12937.7 PRP81464.1 - 0.035 14.0 0.2 0.035 14.0 0.2 1.9 2 0 0 2 2 2 0 F-box-like VWA PF00092.28 PRP81465.1 - 1.6e-28 100.1 0.6 2.5e-28 99.5 0.6 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP81465.1 - 2.5e-11 44.1 0.0 4.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1194 PF06707.11 PRP81465.1 - 0.00062 19.0 0.0 0.004 16.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) Dicty_CTDC PF00526.18 PRP81465.1 - 0.0014 18.5 17.0 0.0022 17.9 3.3 11.3 10 0 0 10 10 10 6 Dictyostelium (slime mold) repeat VWA_3 PF13768.6 PRP81465.1 - 0.0067 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2613 PF11021.8 PRP81465.1 - 6.9 6.9 12.3 2.6 8.2 8.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) ubiquitin PF00240.23 PRP81466.1 - 6.1e-26 90.0 2.2 4.4e-15 55.2 0.5 2.9 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 PRP81466.1 - 2.6e-09 36.8 0.5 0.023 14.5 0.0 3.7 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 PRP81466.1 - 3.9e-09 36.5 10.3 9.2e-09 35.3 10.3 1.7 1 0 0 1 1 1 1 AN1-like Zinc finger TOM20_plant PF06552.12 PRP81466.1 - 7.9e-07 29.0 0.2 0.0016 18.2 0.0 3.0 2 1 1 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 F-box_4 PF15966.5 PRP81466.1 - 3.9e-06 26.7 0.3 1.3e-05 25.0 0.3 1.9 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 PRP81466.1 - 0.0028 17.5 0.1 0.0082 16.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP81466.1 - 0.0046 16.8 0.1 0.013 15.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.6 PRP81466.1 - 0.015 15.0 10.4 4.2 7.1 0.2 4.2 4 0 0 4 4 4 0 TPR repeat Ubiquitin_2 PF14560.6 PRP81466.1 - 0.019 15.4 0.9 0.046 14.2 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain TPR_17 PF13431.6 PRP81466.1 - 0.043 14.2 5.2 0.068 13.6 0.1 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat Ubiquitin_4 PF18036.1 PRP81466.1 - 0.066 13.3 7.2 8.2 6.6 0.0 4.8 4 2 0 4 4 3 0 Ubiquitin-like domain TPR_10 PF13374.6 PRP81466.1 - 0.13 12.2 4.0 27 4.8 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP81466.1 - 0.24 12.3 9.0 45 5.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PHD PF00628.29 PRP81468.1 - 3.3e-08 33.3 11.7 6.3e-08 32.4 11.7 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 PRP81468.1 - 0.04 14.2 3.4 0.092 13.0 3.4 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain CASP_C PF08172.12 PRP81469.1 - 2e-54 184.6 16.0 2e-54 184.6 16.0 5.5 2 1 4 6 6 4 1 CASP C terminal GAS PF13851.6 PRP81469.1 - 0.002 17.5 69.7 0.072 12.4 4.7 6.3 3 1 3 6 6 6 5 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 PRP81469.1 - 0.0035 17.5 0.5 0.0035 17.5 0.5 6.0 2 1 2 5 5 3 2 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.8 PRP81469.1 - 0.071 13.3 0.4 0.071 13.3 0.4 6.8 3 2 0 5 5 5 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 PRP81469.1 - 0.1 12.2 69.5 0.02 14.5 9.9 5.9 1 1 2 5 5 5 0 Intermediate filament protein FUSC PF04632.12 PRP81469.1 - 0.15 10.5 21.9 0.18 10.3 6.5 2.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family Tektin PF03148.14 PRP81469.1 - 2.7 6.7 54.6 0.081 11.7 8.0 5.7 2 1 3 5 5 5 0 Tektin family CCM2_C PF16545.5 PRP81469.1 - 4 8.0 8.6 60 4.2 0.1 4.2 3 1 0 3 3 3 0 Cerebral cavernous malformation protein, harmonin-homology LURAP PF14854.6 PRP81469.1 - 4.9 7.1 12.4 5.6 7.0 0.1 4.0 4 1 0 4 4 4 0 Leucine rich adaptor protein DUF4407 PF14362.6 PRP81469.1 - 5.7 6.2 52.9 4.8 6.5 2.9 4.3 1 1 1 2 2 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 PRP81469.1 - 9 6.5 38.0 1.8 8.7 3.1 7.6 6 3 0 6 6 6 0 bZIP transcription factor PKD_channel PF08016.12 PRP81470.1 - 7.4e-53 179.7 5.6 1.5e-52 178.8 5.6 1.5 1 1 0 1 1 1 1 Polycystin cation channel CVNH PF08881.10 PRP81470.1 - 1.1e-27 96.7 0.0 3.1e-10 40.6 0.0 4.0 3 1 1 4 4 4 4 CVNH domain Ion_trans PF00520.31 PRP81470.1 - 2.3e-09 36.9 19.9 4.3e-09 35.9 19.9 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 PRP81470.1 - 6.5e-06 26.6 0.0 2.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81470.1 - 2.7e-05 24.6 0.0 0.0023 18.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP81470.1 - 4.1e-05 23.8 0.3 0.00031 21.0 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81470.1 - 0.0002 21.6 0.2 0.016 15.7 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat PQQ_2 PF13360.6 PRP81470.1 - 0.016 14.8 0.1 0.1 12.2 0.1 2.2 2 0 0 2 2 2 0 PQQ-like domain Ank PF00023.30 PRP81470.1 - 0.017 15.5 0.1 1.2 9.7 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat CM_1 PF07736.11 PRP81470.1 - 0.65 10.4 5.3 0.49 10.8 2.5 2.1 2 0 0 2 2 2 0 Chorismate mutase type I AAA PF00004.29 PRP81474.1 - 1.3e-51 174.5 0.0 6.1e-41 139.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP81474.1 - 3.2e-10 39.6 0.4 1.1e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 PRP81474.1 - 2.2e-09 38.0 2.0 3.2e-05 24.4 0.3 3.6 3 1 0 3 3 3 2 AAA ATPase domain Bromodomain PF00439.25 PRP81474.1 - 1.2e-08 34.9 0.2 2.6e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 Bromodomain AAA_2 PF07724.14 PRP81474.1 - 9e-08 32.4 0.0 6.3e-05 23.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PRP81474.1 - 4.2e-07 30.0 0.0 0.002 18.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP81474.1 - 1e-06 29.1 0.1 0.12 12.7 0.0 3.4 2 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 PRP81474.1 - 3.9e-06 26.7 0.0 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 PRP81474.1 - 0.00018 20.9 0.0 0.53 9.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain DUF2075 PF09848.9 PRP81474.1 - 0.00021 20.6 0.0 0.58 9.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 PRP81474.1 - 0.00023 21.7 1.0 0.028 14.9 0.0 3.9 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 PRP81474.1 - 0.00035 20.7 0.0 0.026 14.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.22 PRP81474.1 - 0.00041 20.7 0.0 0.13 12.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 PRP81474.1 - 0.00068 19.2 0.0 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 PRP81474.1 - 0.00071 19.0 0.0 0.031 13.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 PRP81474.1 - 0.0023 17.7 0.0 0.14 11.8 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 PRP81474.1 - 0.0024 18.1 0.3 0.31 11.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Parvo_NS1 PF01057.17 PRP81474.1 - 0.0045 16.1 0.0 0.088 11.9 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 PRP81474.1 - 0.0051 16.5 0.0 0.27 10.9 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 PRP81474.1 - 0.0086 16.4 0.0 6.3 7.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 PRP81474.1 - 0.0087 16.2 0.1 0.14 12.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PRP81474.1 - 0.01 16.3 0.0 0.26 11.8 0.0 3.1 3 0 0 3 3 3 0 ABC transporter AAA_24 PF13479.6 PRP81474.1 - 0.029 14.1 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP81474.1 - 0.035 13.8 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PRP81474.1 - 0.067 13.1 0.0 7.5 6.4 0.1 2.7 2 1 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 PRP81474.1 - 0.099 12.5 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 PRP81474.1 - 0.26 11.0 13.5 0.53 10.0 0.0 4.0 4 0 0 4 4 3 0 AAA domain AAA_17 PF13207.6 PRP81474.1 - 3.3 8.1 6.9 19 5.7 0.0 3.7 3 0 0 3 3 2 0 AAA domain NHL PF01436.21 PRP81477.1 - 6.8e-21 73.2 0.1 2.8e-06 27.1 0.4 5.0 4 0 0 4 4 4 4 NHL repeat SGL PF08450.12 PRP81477.1 - 4.1e-10 39.7 0.1 1.6e-05 24.6 0.0 4.0 1 1 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 PRP81477.1 - 0.03 14.5 0.0 0.41 10.9 0.0 2.8 3 0 0 3 3 3 0 Arylesterase Thioredoxin_8 PF13905.6 PRP81477.1 - 0.073 13.4 0.1 0.29 11.5 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like Tk-SP_N-pro PF18237.1 PRP81477.1 - 0.22 11.6 0.3 0.53 10.4 0.3 1.6 1 0 0 1 1 1 0 Tk-SP N-propeptide domain Ank_2 PF12796.7 PRP81479.1 - 3.7e-76 251.8 14.9 9e-17 61.5 0.7 8.6 3 1 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81479.1 - 2.4e-72 238.4 16.5 5.3e-12 46.0 0.0 12.6 5 2 8 13 13 13 12 Ankyrin repeats (many copies) Sec7 PF01369.20 PRP81479.1 - 1.4e-66 223.7 3.5 2.8e-66 222.7 3.5 1.5 1 0 0 1 1 1 1 Sec7 domain Ank_5 PF13857.6 PRP81479.1 - 3.5e-55 183.3 21.9 4.3e-10 39.6 0.0 12.1 5 2 8 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 PRP81479.1 - 4.4e-55 181.9 28.1 5.3e-05 23.5 0.1 15.5 16 0 0 16 16 16 11 Ankyrin repeat Ank_3 PF13606.6 PRP81479.1 - 2e-45 147.5 17.5 0.0092 16.4 0.0 15.4 15 0 0 15 15 15 9 Ankyrin repeat PH PF00169.29 PRP81479.1 - 9.9e-24 83.9 0.2 2.8e-23 82.4 0.2 1.9 1 0 0 1 1 1 1 PH domain Lipase_3 PF01764.25 PRP81479.1 - 4e-09 36.5 0.0 9.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PH_11 PF15413.6 PRP81479.1 - 6.3e-07 29.8 1.0 2.9e-06 27.6 1.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PRP81479.1 - 0.002 18.5 0.1 0.0059 17.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PRP81479.1 - 0.08 13.2 0.0 0.47 10.8 0.0 2.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF2974 PF11187.8 PRP81479.1 - 0.083 12.4 0.0 13 5.2 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) Hist_deacetyl PF00850.19 PRP81480.1 - 3.7e-77 259.8 0.1 9.5e-77 258.5 0.0 1.7 2 0 0 2 2 2 1 Histone deacetylase domain NUP50 PF08911.11 PRP81480.1 - 0.0028 18.3 0.4 0.0028 18.3 0.4 2.2 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) BssB_TutG PF18512.1 PRP81480.1 - 0.029 14.3 0.2 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Benzylsuccinate synthase beta subunit FHA_2 PF17913.1 PRP81480.1 - 0.12 12.7 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 FHA domain Spermine_synth PF01564.17 PRP81481.1 - 0.00041 19.8 0.1 0.00058 19.3 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_31 PF13847.6 PRP81481.1 - 0.084 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NTF2 PF02136.20 PRP81482.1 - 5e-09 36.7 0.0 2.2e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain TAP_C PF03943.13 PRP81482.1 - 5.5e-09 35.5 0.6 1.5e-08 34.2 0.6 1.8 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 PRP81482.1 - 8.2e-05 22.3 0.0 0.00023 20.9 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain LRR_4 PF12799.7 PRP81482.1 - 0.00028 21.2 0.1 0.12 12.8 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP81482.1 - 0.0014 18.2 0.0 0.0039 16.7 0.0 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PRP81482.1 - 0.055 13.2 0.3 0.58 10.0 0.0 2.5 1 1 1 2 2 2 0 Leucine rich repeat Y_phosphatase2 PF03162.13 PRP81483.1 - 1.9e-57 193.4 0.0 2.3e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 PRP81483.1 - 1e-06 28.9 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PRP81483.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP81483.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ACT_7 PF13840.6 PRP81484.1 - 5.7e-19 67.7 0.0 5.4e-08 32.5 0.0 3.0 3 0 0 3 3 3 2 ACT domain Transglut_core PF01841.19 PRP81484.1 - 2.5e-11 44.0 0.0 8e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Castor1_N PF18700.1 PRP81484.1 - 1.8e-08 34.1 0.1 1.2e-05 25.1 0.1 2.6 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain EF-hand_4 PF12763.7 PRP81484.1 - 7e-08 32.4 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand COPI_C PF06957.11 PRP81484.1 - 1.3e-07 30.7 4.9 3.4e-07 29.4 4.9 1.6 1 1 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Rhodanese_C PF12368.8 PRP81484.1 - 6.4 7.2 7.2 15 6.0 7.2 1.6 1 0 0 1 1 1 0 Rhodanase C-terminal PRiA4_ORF3 PF07929.11 PRP81485.1 - 1.2e-32 113.1 0.0 1.7e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 PRP81485.1 - 1.5e-10 40.9 17.1 1.5e-10 40.9 17.1 1.7 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 PRP81485.1 - 0.081 13.0 10.0 0.15 12.2 10.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DAO PF01266.24 PRP81486.1 - 3.9e-41 141.8 0.0 4.6e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP81486.1 - 0.00018 21.6 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PRP81486.1 - 0.00022 21.2 0.1 0.63 10.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 PRP81486.1 - 0.00028 20.1 0.0 0.0021 17.2 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 PRP81486.1 - 0.012 14.9 0.0 5.6 6.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PRP81486.1 - 0.016 14.1 0.0 0.35 9.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 PRP81486.1 - 0.022 14.0 0.1 0.055 12.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 PRP81486.1 - 0.091 11.8 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 PRP81486.1 - 0.13 11.5 0.0 0.38 10.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Chlam_PMP PF02415.17 PRP81488.1 - 0.026 15.0 0.3 0.026 15.0 0.3 3.8 3 1 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF4191 PF13829.6 PRP81488.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3737 PF12541.8 PRP81489.1 - 0.14 11.3 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3737) Sugar_tr PF00083.24 PRP81490.1 - 7.1e-43 147.1 13.6 1.1e-42 146.4 13.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP81490.1 - 6.9e-28 97.6 41.3 1.6e-24 86.5 16.2 3.0 3 1 1 4 4 4 2 Major Facilitator Superfamily MFS_2 PF13347.6 PRP81490.1 - 8e-05 21.4 20.5 0.0034 16.0 19.3 2.6 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_4 PF06779.14 PRP81490.1 - 0.0002 20.8 19.3 0.00025 20.5 4.9 2.2 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF2768 PF10966.8 PRP81490.1 - 1.6 9.3 0.0 1.6 9.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2768) PALP PF00291.25 PRP81491.1 - 0.0001 21.8 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1349 PF07081.11 PRP81492.1 - 2.4e-29 102.3 0.0 2.7e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) CathepsinC_exc PF08773.11 PRP81492.1 - 0.061 13.6 0.0 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 Cathepsin C exclusion domain hGDE_central PF14702.6 PRP81493.1 - 0.17 11.5 0.0 0.19 11.4 0.0 1.0 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme Snf7 PF03357.21 PRP81494.1 - 2.9e-13 49.8 7.2 3.5e-13 49.5 7.2 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 PRP81494.1 - 3.4e-06 27.1 2.8 4.5e-06 26.7 2.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 PRP81494.1 - 0.17 11.5 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Ank_2 PF12796.7 PRP81495.1 - 4.8e-24 84.8 0.0 5.2e-07 30.2 0.0 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81495.1 - 5.7e-18 65.0 0.1 0.013 16.1 0.0 5.8 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP81495.1 - 6.6e-13 48.6 0.1 0.29 11.5 0.0 6.8 4 2 3 7 7 7 4 Ankyrin repeats (many copies) FERM_M PF00373.18 PRP81495.1 - 1e-12 48.5 0.0 2.8e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 FERM central domain Ank PF00023.30 PRP81495.1 - 3.6e-09 36.6 0.5 5.3 7.7 0.0 7.2 6 1 0 6 6 6 2 Ankyrin repeat WW PF00397.26 PRP81495.1 - 1.3e-07 31.5 2.4 3e-07 30.4 2.4 1.6 1 0 0 1 1 1 1 WW domain Ank_3 PF13606.6 PRP81495.1 - 4.7e-06 26.6 0.1 12 6.9 0.0 6.6 6 0 0 6 6 6 1 Ankyrin repeat LRR_1 PF00560.33 PRP81495.1 - 7.2e-05 22.8 6.7 15 6.6 0.0 7.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP81495.1 - 0.03 14.4 33.9 9.6 6.6 0.4 10.8 11 0 0 11 11 11 0 Leucine Rich repeat LRR_4 PF12799.7 PRP81495.1 - 0.5 10.9 20.5 5.8 7.5 1.2 7.0 6 1 4 10 10 10 0 Leucine Rich repeats (2 copies) Esterase_phd PF10503.9 PRP81496.1 - 2.5e-07 30.4 0.1 4.1e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 PRP81496.1 - 0.0021 17.6 0.1 0.004 16.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PRP81496.1 - 0.0045 16.3 0.0 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP81496.1 - 0.0062 17.2 1.4 0.011 16.3 1.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 PRP81496.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 PRP81496.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 PRP81496.1 - 0.04 13.8 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 PRP81496.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Pectate_lyase_3 PF12708.7 PRP81497.1 - 1.7e-37 129.3 14.1 2.3e-32 112.6 8.1 5.5 4 1 2 6 6 6 3 Pectate lyase superfamily protein Pentapeptide_3 PF13576.6 PRP81497.1 - 0.0018 18.4 4.9 0.0018 18.4 4.9 5.1 4 1 0 4 4 4 1 Pentapeptide repeats (9 copies) Pectate_lyase_3 PF12708.7 PRP81499.1 - 8.6e-40 136.9 10.8 1.4e-35 123.1 6.0 5.3 5 1 0 5 5 5 2 Pectate lyase superfamily protein SET PF00856.28 PRP81499.1 - 9.3e-09 35.9 0.1 3.4e-07 30.8 0.1 3.1 2 1 0 2 2 2 1 SET domain Complex1_LYR PF05347.15 PRP81500.1 - 1.3e-09 37.9 0.8 2.6e-09 37.0 0.8 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) DNase-RNase PF02577.14 PRP81500.1 - 0.075 12.7 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Bifunctional nuclease Tma16 PF11176.8 PRP81500.1 - 0.25 11.2 5.4 0.31 10.9 5.4 1.1 1 0 0 1 1 1 0 Translation machinery-associated protein 16 DUF2070 PF09843.9 PRP81501.1 - 0.22 9.8 5.3 0.3 9.3 5.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4870 PF09685.10 PRP81501.1 - 0.39 10.9 5.6 0.55 10.4 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) zf-UBR PF02207.20 PRP81502.1 - 1.1e-19 70.4 10.1 1.1e-19 70.4 10.1 2.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) E3_UbLigase_R4 PF13764.6 PRP81502.1 - 1.1e-05 23.8 2.9 2.3e-05 22.8 2.9 1.4 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 UCMA PF17085.5 PRP81502.1 - 0.63 10.1 3.3 1.6 8.8 3.3 1.6 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Peptidase_M24 PF00557.24 PRP81504.1 - 6.6e-36 124.0 0.0 9.8e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Homeodomain PF00046.29 PRP81504.1 - 6.3e-13 48.4 5.2 1.4e-12 47.2 5.2 1.6 1 0 0 1 1 1 1 Homeodomain Chitin_bind_1 PF00187.19 PRP81505.1 - 1.7e-08 34.8 22.8 5e-08 33.3 22.8 1.8 1 0 0 1 1 1 1 Chitin recognition protein Cellulase PF00150.18 PRP81505.1 - 0.0045 16.5 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sacchrp_dh_C PF16653.5 PRP81506.1 - 5.6e-24 85.7 0.1 6.4e-24 85.5 0.1 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain IBR PF01485.21 PRP81507.1 - 8.5e-12 45.1 29.7 5.3e-08 33.0 5.3 3.8 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PRP81507.1 - 1.8e-07 31.4 3.6 1.8e-07 31.4 3.6 4.5 2 1 2 4 4 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP81507.1 - 6.6e-07 29.1 4.5 6.6e-07 29.1 4.5 5.2 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP81507.1 - 2.5e-06 27.2 4.3 2.5e-06 27.2 4.3 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP81507.1 - 9.3e-06 25.6 2.7 9.3e-06 25.6 2.7 3.4 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 PRP81507.1 - 0.00088 19.0 2.9 0.0037 17.0 2.9 2.2 1 0 0 1 1 1 1 RING-like zinc finger FYVE PF01363.21 PRP81507.1 - 0.001 19.1 2.0 0.001 19.1 2.0 3.5 2 1 1 3 3 3 2 FYVE zinc finger zf-RING_5 PF14634.6 PRP81507.1 - 0.002 18.0 4.7 0.002 18.0 4.7 4.9 2 1 2 4 4 2 1 zinc-RING finger domain zf-piccolo PF05715.13 PRP81507.1 - 0.0028 17.8 7.0 0.0028 17.8 7.0 3.5 3 0 0 3 3 3 1 Piccolo Zn-finger zf-C3HC4_4 PF15227.6 PRP81507.1 - 0.0039 17.3 3.7 0.0039 17.3 3.7 4.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Zn_Tnp_IS1595 PF12760.7 PRP81507.1 - 0.016 15.2 2.0 0.016 15.2 2.0 4.6 2 1 3 5 5 3 0 Transposase zinc-ribbon domain DnaJ PF00226.31 PRP81508.1 - 0.011 15.8 0.0 0.041 14.0 0.0 2.0 1 0 0 1 1 1 0 DnaJ domain RHH_1 PF01402.21 PRP81508.1 - 0.051 13.5 0.5 8.9 6.4 0.2 3.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family PP2C_2 PF13672.6 PRP81508.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C Abhydrolase_2 PF02230.16 PRP81510.1 - 0.0022 17.8 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 PRP81510.1 - 0.0052 16.1 0.0 0.029 13.6 0.0 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Mito_fiss_Elm1 PF06258.11 PRP81510.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 SAP PF02037.27 PRP81513.1 - 2.9e-07 30.1 0.6 5.5e-07 29.2 0.6 1.4 1 0 0 1 1 1 1 SAP domain TT_ORF1 PF02956.14 PRP81513.1 - 0.03 13.0 0.3 0.04 12.6 0.3 1.1 1 0 0 1 1 1 0 TT viral orf 1 NAD_binding_6 PF08030.12 PRP81514.1 - 7.2e-29 100.9 0.0 1.3e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PRP81514.1 - 1.5e-21 76.5 0.0 3.5e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 PRP81514.1 - 5.5e-15 55.6 11.6 1.2e-14 54.6 11.6 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 PRP81514.1 - 0.00025 21.6 0.0 0.0026 18.4 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain EF-hand_6 PF13405.6 PRP81514.1 - 0.00097 18.9 0.1 0.17 11.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 PRP81514.1 - 0.05 13.2 0.0 0.44 10.2 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 PRP81514.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain DUF1476 PF07345.11 PRP81514.1 - 0.25 11.7 1.8 0.67 10.4 1.8 1.7 1 0 0 1 1 1 0 ATPase inhibitor subunit zeta Exo_endo_phos PF03372.23 PRP81515.1 - 3.5e-11 43.1 0.0 5.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.27 PRP81515.1 - 7.2e-10 38.9 0.0 2.3e-08 34.0 0.0 2.7 1 1 0 1 1 1 1 RhoGAP domain PapD-like PF14874.6 PRP81515.1 - 0.012 15.7 0.1 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 Flagellar-associated PapD-like Adaptin_N PF01602.20 PRP81516.1 - 2.2e-112 376.3 8.7 2.7e-112 376.0 8.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 PRP81516.1 - 8.4e-24 83.9 0.0 1.9e-22 79.6 0.0 2.5 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 PRP81516.1 - 1.6e-12 47.7 0.2 1.6e-12 47.7 0.2 2.3 3 0 0 3 3 3 1 Adaptin C-terminal domain Cnd1 PF12717.7 PRP81516.1 - 3.7e-06 27.1 1.1 0.012 15.6 0.0 2.8 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PRP81516.1 - 0.017 15.5 2.9 6.6 7.2 0.1 3.6 2 1 1 3 3 3 0 HEAT repeats Vitellogenin_N PF01347.22 PRP81516.1 - 0.034 12.6 0.1 0.061 11.7 0.1 1.3 1 0 0 1 1 1 0 Lipoprotein amino terminal region Antimicrobial_3 PF08025.11 PRP81516.1 - 0.34 10.9 2.5 0.44 10.5 0.9 2.0 2 0 0 2 2 2 0 Spider antimicrobial peptide HEAT_EZ PF13513.6 PRP81516.1 - 1.6 9.4 4.8 13 6.4 0.1 3.8 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 PRP81516.1 - 4.4 7.8 8.6 7.4 7.1 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat Vps26 PF03643.15 PRP81517.1 - 9.1e-92 307.0 1.7 1.3e-91 306.5 1.7 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 START PF01852.19 PRP81517.1 - 4.4e-05 23.0 0.0 0.064 12.7 0.0 2.4 2 0 0 2 2 2 2 START domain Carb_bind PF10645.9 PRP81517.1 - 0.021 15.0 12.8 0.058 13.6 12.8 1.9 1 0 0 1 1 1 0 Carbohydrate binding DUF3074 PF11274.8 PRP81517.1 - 0.078 12.9 2.3 0.49 10.3 2.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3074) FAM76 PF16046.5 PRP81518.1 - 0.079 12.3 15.3 0.1 12.0 15.3 1.2 1 0 0 1 1 1 0 FAM76 protein DUF3552 PF12072.8 PRP81518.1 - 0.79 9.1 16.4 0.91 8.9 15.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Glyco_transf_34 PF05637.12 PRP81518.1 - 1.3 8.6 6.4 0.28 10.9 1.1 2.0 1 1 1 2 2 2 0 galactosyl transferase GMA12/MNN10 family UIM PF02809.20 PRP81519.1 - 0.00044 20.0 0.8 0.00044 20.0 0.8 3.9 2 1 0 2 2 2 1 Ubiquitin interaction motif Prok-RING_4 PF14447.6 PRP81519.1 - 0.017 15.0 9.3 0.11 12.4 5.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PRP81519.1 - 0.66 9.9 9.5 1.1 9.1 9.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP81519.1 - 0.75 9.7 9.6 1.4 8.9 9.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AMP-binding PF00501.28 PRP81520.1 - 9.4e-94 314.4 0.0 1.2e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP81520.1 - 1e-15 58.4 0.0 2.2e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Biopterin_H PF00351.21 PRP81521.1 - 1.2e-155 517.6 0.0 1.4e-155 517.4 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 PRP81521.1 - 3.4e-08 33.1 0.0 7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 ACT domain GAS PF13851.6 PRP81522.1 - 0.00074 18.9 3.3 0.00074 18.9 3.3 3.0 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 PRP81522.1 - 0.0061 17.0 17.8 0.021 15.3 13.2 2.3 1 1 1 2 2 2 2 Fez1 TPR_MLP1_2 PF07926.12 PRP81522.1 - 0.063 13.4 21.6 0.042 13.9 8.0 2.9 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 PRP81522.1 - 0.15 11.3 12.0 0.043 13.1 1.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4337 PF14235.6 PRP81522.1 - 0.3 11.2 13.1 0.076 13.1 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) KfrA_N PF11740.8 PRP81522.1 - 0.42 11.3 7.3 0.52 11.0 0.9 2.9 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term DUF4407 PF14362.6 PRP81522.1 - 0.62 9.4 6.9 0.15 11.4 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4972 PF16342.5 PRP81522.1 - 0.64 9.7 6.8 0.12 12.1 0.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) Jnk-SapK_ap_N PF09744.9 PRP81522.1 - 1.9 8.7 23.2 0.092 13.0 7.3 2.9 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 BRI3BP PF14965.6 PRP81522.1 - 7.5 6.0 6.6 23 4.5 0.2 2.9 3 0 0 3 3 3 0 Negative regulator of p53/TP53 FAM76 PF16046.5 PRP81522.1 - 9.9 5.4 14.2 4.3 6.6 0.9 3.0 2 1 0 3 3 3 0 FAM76 protein BSD PF03909.17 PRP81523.1 - 4.6e-07 29.7 0.8 1.2e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 BSD domain eIF3_subunit PF08597.10 PRP81523.1 - 0.00017 21.6 5.6 0.00034 20.6 5.6 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Vfa1 PF08432.10 PRP81523.1 - 0.00079 19.8 2.3 0.0018 18.7 2.3 1.5 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 PRP81523.1 - 0.015 15.0 3.2 0.015 15.0 3.2 1.7 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 PRP81523.1 - 0.042 13.8 8.2 0.073 13.0 8.2 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CLN3 PF02487.17 PRP81523.1 - 0.14 11.2 0.6 0.19 10.7 0.6 1.1 1 0 0 1 1 1 0 CLN3 protein DUF1682 PF07946.14 PRP81523.1 - 0.16 11.1 9.7 0.34 10.1 9.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Connexin PF00029.19 PRP81523.1 - 0.33 10.7 2.1 0.49 10.1 2.1 1.2 1 0 0 1 1 1 0 Connexin DUF3824 PF12868.7 PRP81523.1 - 0.99 10.1 8.9 1 10.0 8.0 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Presenilin PF01080.17 PRP81523.1 - 1.1 7.9 4.8 1.5 7.5 4.8 1.1 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 PRP81523.1 - 2 7.2 9.9 3 6.7 9.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Afi1 PF07792.12 PRP81523.1 - 6.3 7.3 10.5 0.77 10.2 5.5 1.9 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking HNH_2 PF13391.6 PRP81527.1 - 4.3e-05 23.6 0.0 9.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Aldedh PF00171.22 PRP81528.1 - 5.6e-175 582.3 0.0 6.8e-175 582.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 PRP81528.1 - 0.023 14.2 0.0 0.061 12.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) WD40 PF00400.32 PRP81531.1 - 6.1e-63 207.3 18.2 6.5e-11 42.6 0.0 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP81531.1 - 2.4e-27 95.0 1.4 0.00036 20.8 0.1 6.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP81531.1 - 4.2e-15 56.1 0.7 4.4e-08 33.2 0.1 4.1 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PRP81531.1 - 1.1e-12 47.4 6.5 0.036 12.7 0.2 5.1 1 1 4 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 PRP81531.1 - 4.8e-08 32.7 0.1 0.02 14.3 0.0 3.8 1 1 4 5 5 5 4 WD40-like domain Ge1_WD40 PF16529.5 PRP81531.1 - 4.9e-06 25.7 4.2 0.26 10.2 0.0 4.3 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PRP81531.1 - 0.00086 17.9 0.1 0.35 9.3 0.0 3.1 1 1 3 4 4 4 2 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 PRP81531.1 - 0.0013 17.7 2.2 11 4.8 0.0 4.6 1 1 3 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 PRP81531.1 - 0.0023 16.4 0.0 0.15 10.4 0.0 2.2 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 PRP81531.1 - 0.0037 16.1 3.6 0.9 8.2 0.4 3.6 1 1 2 3 3 3 2 Nup133 N terminal like PD40 PF07676.12 PRP81531.1 - 0.0072 16.2 0.7 1.7 8.7 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 PRP81531.1 - 0.0098 13.9 0.1 0.016 13.3 0.1 1.2 1 0 0 1 1 1 1 IKI3 family VID27 PF08553.10 PRP81531.1 - 0.046 12.8 0.0 0.7 8.9 0.0 2.6 1 1 1 3 3 3 0 VID27 C-terminal WD40-like domain CbtA PF09490.10 PRP81531.1 - 0.19 11.5 0.2 0.29 10.9 0.2 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) ATP-synt_F PF01990.17 PRP81532.1 - 6.4e-33 112.9 0.5 7.5e-33 112.7 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit adh_short PF00106.25 PRP81533.1 - 7.8e-29 100.5 0.2 1e-28 100.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP81533.1 - 2.4e-22 79.7 0.0 3.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP81533.1 - 6.8e-06 26.1 0.1 9.4e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PRP81533.1 - 0.023 14.1 0.0 0.068 12.5 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Aminotran_1_2 PF00155.21 PRP81534.1 - 1.2e-57 195.8 0.0 1.5e-57 195.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PRP81534.1 - 0.00093 18.6 0.0 0.0065 15.8 0.0 1.9 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 PRP81534.1 - 0.0081 15.1 0.0 0.03 13.3 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PRP81534.1 - 0.17 11.2 0.0 1 8.6 0.0 2.0 1 1 0 1 1 1 0 Beta-eliminating lyase Ras PF00071.22 PRP81535.1 - 8.2e-53 178.3 0.0 9.4e-53 178.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP81535.1 - 4.7e-20 72.0 0.0 6.8e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP81535.1 - 8.9e-08 31.8 0.0 9.8e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP81535.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP81535.1 - 0.0023 18.0 0.0 0.0033 17.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4318 PF14201.6 PRP81535.1 - 0.061 13.8 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) PMT PF02366.18 PRP81535.1 - 0.092 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase 2OG-FeII_Oxy_3 PF13640.6 PRP81536.1 - 0.023 15.6 0.0 0.069 14.1 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 PRP81536.1 - 0.097 12.9 0.0 0.98 9.6 0.0 2.2 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Homeodomain PF00046.29 PRP81537.1 - 5.9e-14 51.7 2.2 1.5e-13 50.4 2.2 1.7 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PRP81537.1 - 0.014 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 PRP81537.1 - 0.017 15.0 0.2 0.072 13.0 0.0 2.1 2 0 0 2 2 2 0 Homeobox KN domain YdaS_antitoxin PF15943.5 PRP81537.1 - 0.041 13.8 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Uroplakin_II PF07353.12 PRP81538.1 - 0.055 13.0 0.2 0.36 10.3 0.0 2.1 1 1 1 2 2 2 0 Uroplakin II DUF3060 PF11259.8 PRP81538.1 - 0.079 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) HisKA_2 PF07568.12 PRP81539.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase FAM110_N PF14161.6 PRP81539.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Centrosome-associated N terminus YrhK PF14145.6 PRP81540.1 - 8.6e-12 44.8 29.2 2.3e-07 30.6 3.0 3.5 3 1 0 3 3 3 3 YrhK-like protein STAG PF08514.11 PRP81541.1 - 1.8 8.5 3.9 20 5.1 0.3 2.2 2 0 0 2 2 2 0 STAG domain F-box PF00646.33 PRP81542.1 - 6.1e-08 32.4 1.1 1.3e-07 31.3 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP81542.1 - 5.4e-05 23.0 0.2 0.00012 21.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like Med7 PF05983.11 PRP81544.1 - 1.5e-42 145.9 7.5 2.4e-42 145.2 7.5 1.3 1 1 0 1 1 1 1 MED7 protein ParE-like_toxin PF15781.5 PRP81544.1 - 0.00055 19.8 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 ParE-like toxin of type II bacterial toxin-antitoxin system LMP PF04778.12 PRP81544.1 - 0.0036 17.2 1.5 0.0047 16.8 1.5 1.1 1 0 0 1 1 1 1 LMP repeated region Na_Ca_ex_C PF16494.5 PRP81544.1 - 0.19 12.2 3.6 0.25 11.8 2.2 1.8 1 1 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain CI-B14_5a PF07347.12 PRP81544.1 - 0.27 11.1 3.0 0.55 10.1 0.3 2.1 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Mod_r PF07200.13 PRP81544.1 - 0.28 11.3 7.1 0.19 11.8 2.1 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nop PF01798.18 PRP81545.1 - 3.8e-63 213.0 1.4 4e-63 213.0 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 PRP81545.1 - 5.6e-32 111.2 2.9 5.6e-32 111.2 2.9 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain OmpH PF03938.14 PRP81545.1 - 0.33 11.3 6.3 0.14 12.5 3.2 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ion_trans PF00520.31 PRP81546.1 - 8.6e-18 64.5 12.6 1.1e-17 64.1 12.6 1.1 1 0 0 1 1 1 1 Ion transport protein DUF962 PF06127.11 PRP81546.1 - 0.089 12.9 0.3 0.28 11.3 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) PalH PF08733.10 PRP81546.1 - 0.12 11.3 10.4 0.18 10.8 1.8 2.4 2 1 0 2 2 2 0 PalH/RIM21 DnaJ-X PF14308.6 PRP81547.1 - 1e-36 126.4 3.2 1.8e-36 125.6 3.2 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 PRP81547.1 - 6.7e-24 83.8 1.0 1.4e-23 82.8 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain MCM2_N PF12619.8 PRP81547.1 - 0.098 12.9 3.0 0.19 12.0 3.0 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 RNHCP PF12647.7 PRP81547.1 - 0.47 10.5 4.1 1.2 9.1 0.3 2.5 3 0 0 3 3 3 0 RNHCP domain Pkinase PF00069.25 PRP81548.1 - 1.3e-54 185.3 0.0 1.6e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81548.1 - 9.9e-28 97.1 0.0 1.3e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP81548.1 - 0.0056 16.6 0.3 0.016 15.2 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP81548.1 - 0.0077 15.6 0.4 0.016 14.6 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP81548.1 - 0.051 13.2 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UCH PF00443.29 PRP81549.1 - 4.6e-35 121.4 0.5 5.7e-35 121.0 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP81549.1 - 1.4e-08 34.7 1.1 1.3e-07 31.5 1.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PaREP1 PF05942.11 PRP81550.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family RasGEF PF00617.19 PRP81551.1 - 1e-30 107.3 0.1 1.9e-30 106.4 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain PH PF00169.29 PRP81551.1 - 3.2e-16 59.7 0.1 9.5e-16 58.2 0.1 1.9 1 0 0 1 1 1 1 PH domain RasGEF_N PF00618.20 PRP81551.1 - 1.6e-09 37.9 2.0 1.4e-06 28.5 2.0 2.6 1 1 0 1 1 1 1 RasGEF N-terminal motif PH_11 PF15413.6 PRP81551.1 - 0.043 14.2 0.4 0.35 11.3 0.4 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain ADK PF00406.22 PRP81552.1 - 2.8e-60 202.8 0.0 3.4e-60 202.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PRP81552.1 - 2.9e-23 82.8 0.1 1.2e-22 80.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 PRP81552.1 - 4.5e-17 61.7 0.1 1.4e-16 60.2 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 PRP81552.1 - 6.8e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 PRP81552.1 - 0.00012 22.4 1.0 0.0078 16.5 0.1 2.2 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 PRP81552.1 - 0.19 12.3 0.1 0.6 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain SAP18 PF06487.12 PRP81553.1 - 1.6e-22 80.2 0.0 3.3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Copine PF07002.16 PRP81554.1 - 1.3e-25 90.1 0.0 1.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 PRP81554.1 - 1.5e-23 83.1 0.0 9.3e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain DUF3278 PF11683.8 PRP81555.1 - 0.012 15.7 0.5 0.016 15.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) LBR_tudor PF09465.10 PRP81555.1 - 0.079 12.8 1.5 0.11 12.3 0.2 1.9 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain MciZ PF13072.6 PRP81555.1 - 0.9 9.4 4.4 0.52 10.2 0.4 2.4 3 0 0 3 3 3 0 Mother cell inhibitor of FtsZ Ribosomal_L23 PF00276.20 PRP81556.1 - 6.4e-13 48.9 2.7 1.2e-12 48.0 2.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Arm-DNA-bind_4 PF14657.6 PRP81556.1 - 0.0088 15.8 0.3 0.022 14.5 0.3 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Ribosomal_S24e PF01282.19 PRP81556.1 - 0.021 14.7 0.3 4.4 7.3 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S24e ZapB PF06005.12 PRP81557.1 - 0.0016 18.8 2.2 0.0026 18.2 1.4 1.7 2 1 0 2 2 2 1 Cell division protein ZapB HALZ PF02183.18 PRP81557.1 - 0.0039 17.4 4.2 0.0072 16.5 4.2 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 PRP81557.1 - 0.0052 16.9 2.4 0.0098 16.0 2.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 PRP81557.1 - 0.0095 15.7 2.8 0.014 15.1 2.1 1.6 2 0 0 2 2 2 1 Septum formation initiator TMF_DNA_bd PF12329.8 PRP81557.1 - 0.011 15.7 2.8 0.023 14.7 2.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SHE3 PF17078.5 PRP81557.1 - 0.021 14.5 1.7 0.085 12.6 1.2 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 PRP81557.1 - 0.021 14.9 2.6 0.039 14.0 2.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Cnn_1N PF07989.11 PRP81557.1 - 0.023 14.8 4.7 0.058 13.6 4.7 2.0 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 CdvA PF18822.1 PRP81557.1 - 0.025 14.4 1.2 0.028 14.3 0.4 1.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 PRP81557.1 - 0.025 14.9 3.2 0.027 14.9 0.7 2.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.9 PRP81557.1 - 0.044 13.7 0.2 0.052 13.5 0.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain N1221 PF07923.13 PRP81557.1 - 0.058 12.6 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 N1221-like protein Herpes_UL6 PF01763.16 PRP81557.1 - 0.097 11.2 0.1 0.091 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Shugoshin_N PF07558.11 PRP81557.1 - 0.11 12.3 1.6 0.19 11.6 1.6 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CENP-H PF05837.12 PRP81557.1 - 0.2 12.0 2.7 0.26 11.7 2.7 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Fip1 PF05182.13 PRP81559.1 - 0.52 9.9 1.3 1.4 8.5 0.2 2.0 2 0 0 2 2 2 0 Fip1 motif Sec1 PF00995.23 PRP81561.1 - 5.6e-123 412.2 1.7 6.4e-123 412.0 1.7 1.0 1 0 0 1 1 1 1 Sec1 family ComZ PF10815.8 PRP81561.1 - 0.077 13.0 0.4 0.29 11.2 0.4 2.0 1 0 0 1 1 1 0 ComZ ZapB PF06005.12 PRP81563.1 - 0.0016 18.8 2.2 0.0026 18.2 1.4 1.7 2 1 0 2 2 2 1 Cell division protein ZapB HALZ PF02183.18 PRP81563.1 - 0.0039 17.4 4.2 0.0072 16.5 4.2 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 PRP81563.1 - 0.0052 16.9 2.4 0.0098 16.0 2.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 PRP81563.1 - 0.0095 15.7 2.8 0.014 15.1 2.1 1.6 2 0 0 2 2 2 1 Septum formation initiator TMF_DNA_bd PF12329.8 PRP81563.1 - 0.011 15.7 2.8 0.023 14.7 2.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SHE3 PF17078.5 PRP81563.1 - 0.021 14.5 1.7 0.085 12.6 1.2 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 PRP81563.1 - 0.021 14.9 2.6 0.039 14.0 2.6 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Cnn_1N PF07989.11 PRP81563.1 - 0.023 14.8 4.7 0.058 13.6 4.7 2.0 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 CdvA PF18822.1 PRP81563.1 - 0.025 14.4 1.2 0.028 14.3 0.4 1.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 PRP81563.1 - 0.025 14.9 3.2 0.027 14.9 0.7 2.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Ax_dynein_light PF10211.9 PRP81563.1 - 0.044 13.7 0.2 0.052 13.5 0.2 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain N1221 PF07923.13 PRP81563.1 - 0.058 12.6 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 N1221-like protein Herpes_UL6 PF01763.16 PRP81563.1 - 0.097 11.2 0.1 0.091 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Shugoshin_N PF07558.11 PRP81563.1 - 0.11 12.3 1.6 0.19 11.6 1.6 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region CENP-H PF05837.12 PRP81563.1 - 0.2 12.0 2.7 0.26 11.7 2.7 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Ribosomal_L23 PF00276.20 PRP81564.1 - 6.4e-13 48.9 2.7 1.2e-12 48.0 2.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Arm-DNA-bind_4 PF14657.6 PRP81564.1 - 0.0088 15.8 0.3 0.022 14.5 0.3 1.7 1 0 0 1 1 1 1 Arm DNA-binding domain Ribosomal_S24e PF01282.19 PRP81564.1 - 0.021 14.7 0.3 4.4 7.3 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S24e DUF2838 PF10998.8 PRP81565.1 - 4.2e-31 107.5 8.5 4.2e-31 107.5 8.5 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Kinesin PF00225.23 PRP81566.1 - 3e-109 365.0 0.1 5.5e-109 364.1 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PRP81566.1 - 9.6e-26 90.5 1.8 1.7e-25 89.7 0.3 2.3 2 0 0 2 2 2 1 Microtubule binding EF-hand_9 PF14658.6 PRP81566.1 - 2.3e-05 24.6 0.0 5.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 PRP81566.1 - 0.00013 21.3 1.7 0.0055 16.2 0.0 3.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 PRP81566.1 - 0.00038 20.1 1.2 0.0029 17.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 PRP81566.1 - 0.00049 20.5 0.0 0.0036 17.7 0.0 2.6 1 0 0 1 1 1 1 EF-hand domain pair SMAP PF15477.6 PRP81566.1 - 2.4 9.2 4.5 1.4 9.9 0.1 3.0 3 0 0 3 3 3 0 Small acidic protein family Ank_2 PF12796.7 PRP81567.1 - 9.6e-07 29.3 0.0 1.4e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP81567.1 - 0.00026 21.2 0.0 0.18 12.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP81567.1 - 0.0025 18.3 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP81567.1 - 0.14 12.6 0.2 0.48 11.0 0.1 1.9 2 0 0 2 2 2 0 Ankyrin repeat T2SSB PF16537.5 PRP81568.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system protein B DUF4520 PF15016.6 PRP81569.1 - 1.4e-18 66.7 0.0 7e-18 64.5 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4520) DUF4524 PF15025.6 PRP81569.1 - 1e-09 38.3 0.0 7.9e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4524) Abhydrolase_6 PF12697.7 PRP81570.1 - 0.015 16.0 0.0 0.034 14.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 PRP81570.1 - 0.044 13.6 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.20 PRP81570.1 - 0.13 11.9 0.2 0.91 9.1 0.1 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_M41 PF01434.18 PRP81571.1 - 3.2e-46 157.6 2.5 5.8e-46 156.8 2.5 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PRP81571.1 - 1.2e-43 148.7 0.0 5.1e-43 146.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP81571.1 - 6.5e-08 32.2 0.0 2.2e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PRP81571.1 - 9e-06 26.2 0.0 0.0038 17.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PRP81571.1 - 1.9e-05 24.5 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PRP81571.1 - 8.1e-05 22.6 0.3 0.0018 18.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PRP81571.1 - 0.0007 18.9 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 PRP81571.1 - 0.0053 17.3 0.0 0.017 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 PRP81571.1 - 0.0056 17.0 0.1 0.35 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PRP81571.1 - 0.0099 15.8 0.0 0.036 14.0 0.0 2.0 2 1 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 PRP81571.1 - 0.017 14.8 0.0 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PRP81571.1 - 0.021 14.2 0.2 0.043 13.2 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 PRP81571.1 - 0.022 14.0 0.1 0.067 12.5 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 PRP81571.1 - 0.035 14.6 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 PRP81571.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 PRP81571.1 - 0.058 13.3 0.5 0.57 10.1 0.2 2.2 1 1 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 PRP81571.1 - 0.084 13.3 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 PRP81571.1 - 0.12 12.1 0.0 0.9 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PRP81571.1 - 0.12 11.8 0.0 0.66 9.5 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 PRP81571.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ank_4 PF13637.6 PRP81572.1 - 2.8e-05 24.6 0.1 0.0057 17.2 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81572.1 - 0.002 18.7 0.0 0.0067 17.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box PF00646.33 PRP81572.1 - 0.0036 17.1 0.0 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP81572.1 - 0.022 14.7 0.1 0.042 13.7 0.1 1.5 1 0 0 1 1 1 0 F-box-like DUF647 PF04884.14 PRP81574.1 - 2e-67 227.4 0.3 2.7e-67 226.9 0.3 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Kelch_4 PF13418.6 PRP81574.1 - 1.2e-39 134.0 8.6 1.9e-07 31.0 0.1 7.4 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PRP81574.1 - 1.7e-31 107.8 6.0 3e-06 27.4 0.0 6.8 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP81574.1 - 2.6e-31 106.9 8.7 1.4e-05 25.2 0.6 7.2 4 2 2 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PRP81574.1 - 2.2e-27 94.3 4.6 1.4e-05 24.5 0.0 7.3 7 0 0 7 7 7 6 Kelch motif Kelch_5 PF13854.6 PRP81574.1 - 9e-26 89.4 4.1 0.00017 21.5 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 PRP81574.1 - 2e-14 52.9 11.7 0.0013 18.6 0.0 7.3 7 1 0 7 7 6 4 Kelch motif Ank_4 PF13637.6 PRP81574.1 - 5.2e-11 42.8 0.0 1.9e-07 31.5 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81574.1 - 5.6e-10 39.7 0.0 1.4e-07 32.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PRP81574.1 - 1.6e-05 25.1 0.0 0.9 10.1 0.0 4.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP81574.1 - 0.00083 19.6 0.0 0.022 15.1 0.0 3.1 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81574.1 - 0.00094 19.5 0.0 9.7 7.1 0.0 4.7 6 0 0 6 6 4 1 Ankyrin repeat BTB_2 PF02214.22 PRP81575.1 - 1.1e-17 64.1 0.0 2.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SPRY PF00622.28 PRP81575.1 - 6.7e-05 23.0 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 SPRY domain BTB PF00651.31 PRP81575.1 - 0.047 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 BTB/POZ domain DUF485 PF04341.12 PRP81575.1 - 0.59 10.1 4.0 2.4 8.2 4.0 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF485 ATP1G1_PLM_MAT8 PF02038.16 PRP81575.1 - 9.4 5.8 5.8 13 5.3 2.3 3.1 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family SRF-TF PF00319.18 PRP81576.1 - 1.5e-24 85.2 0.4 2.8e-24 84.4 0.4 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF4116 PF13475.6 PRP81576.1 - 0.13 12.0 0.2 0.33 10.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Casc1_N PF15927.5 PRP81577.1 - 1.7e-28 99.7 25.7 3.5e-28 98.7 25.7 1.6 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus Cyclin_N PF00134.23 PRP81578.1 - 1.7e-23 82.8 0.1 7.3e-20 71.0 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP81578.1 - 0.0003 20.9 0.0 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 PRP81578.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Cyclin C-terminal domain TFIIB PF00382.19 PRP81578.1 - 0.11 12.5 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIIB repeat RasGEF PF00617.19 PRP81579.1 - 3e-55 187.2 2.8 5.2e-55 186.4 0.1 2.4 2 1 1 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 PRP81579.1 - 1.4e-16 60.6 0.3 6e-16 58.6 0.3 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif Aldo_ket_red PF00248.21 PRP81581.1 - 3.2e-26 92.2 0.0 3.3e-20 72.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Peptidase_S49 PF01343.18 PRP81581.1 - 0.09 12.7 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 Peptidase family S49 Epimerase PF01370.21 PRP81582.1 - 2.8e-16 59.7 0.0 1.1e-15 57.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP81582.1 - 2.8e-07 30.3 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PRP81582.1 - 3.9e-06 26.2 0.0 0.0058 15.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 PRP81582.1 - 2.7e-05 23.3 0.0 0.0012 18.0 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ASH PF15780.5 PRP81582.1 - 0.15 12.3 0.0 0.45 10.8 0.0 1.8 1 1 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin RIO1 PF01163.22 PRP81583.1 - 4.3e-12 46.0 0.0 1e-11 44.8 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Pkinase PF00069.25 PRP81583.1 - 8.6e-10 38.4 0.2 9.9e-10 38.2 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP81583.1 - 6.5e-09 36.1 0.0 1.5e-06 28.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP81583.1 - 1.7e-06 27.5 0.0 1.7e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PRP81583.1 - 0.0009 18.6 0.1 0.0014 18.0 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 PRP81583.1 - 0.0016 18.1 0.0 0.014 14.9 0.0 2.0 1 1 1 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 PRP81583.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase WaaY PF06176.11 PRP81583.1 - 0.03 13.9 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 PRP81583.1 - 0.032 13.0 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LPD39 PF18858.1 PRP81583.1 - 0.034 14.2 0.2 0.064 13.3 0.2 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 RB_B PF01857.20 PRP81583.1 - 0.097 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain PP2C PF00481.21 PRP81584.1 - 1.7e-10 41.0 2.2 8.7e-10 38.7 0.1 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C SAM_1 PF00536.30 PRP81584.1 - 7.4e-09 35.9 0.0 2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Hydrolase_4 PF12146.8 PRP81584.1 - 9.3e-08 31.6 0.0 0.00039 19.8 0.0 2.6 2 0 0 2 2 2 2 Serine aminopeptidase, S33 SAM_2 PF07647.17 PRP81584.1 - 1.2e-05 25.4 0.0 3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydrolase_1 PF00561.20 PRP81584.1 - 8.3e-05 22.4 0.0 0.00052 19.7 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 PRP81584.1 - 0.0009 19.0 0.0 0.003 17.2 0.0 1.8 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 PRP81584.1 - 0.002 17.6 0.0 0.055 12.9 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 PRP81584.1 - 0.012 15.4 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase SlyX PF04102.12 PRP81584.1 - 0.033 14.8 3.9 0.19 12.4 3.9 2.4 1 0 0 1 1 1 0 SlyX DLH PF01738.18 PRP81584.1 - 0.048 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 Dienelactone hydrolase family SMRP1 PF15181.6 PRP81584.1 - 0.095 12.3 0.1 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 Spermatid-specific manchette-related protein 1 CEP209_CC5 PF16574.5 PRP81584.1 - 0.22 11.7 10.5 0.02 15.1 5.2 2.0 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 PspB PF06667.12 PRP81584.1 - 8.4 6.5 6.5 1.3 9.1 1.0 2.6 2 1 1 3 3 3 0 Phage shock protein B Guanylate_cyc PF00211.20 PRP81585.1 - 8.7e-29 100.4 0.3 1.7e-28 99.5 0.3 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PRP81586.1 - 8.1e-12 45.0 0.2 1.7e-11 43.9 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP81586.1 - 1.9e-11 44.3 5.7 5.6e-11 42.8 5.7 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP81586.1 - 4.1e-07 29.6 0.1 7.2e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP81586.1 - 2.6e-05 23.9 10.0 0.00021 21.0 4.2 5.1 4 1 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 PRP81586.1 - 6.8e-05 23.2 25.6 0.0019 18.6 5.5 5.1 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP81586.1 - 0.22 11.0 2.7 0.49 9.9 2.7 1.6 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 PRP81586.1 - 0.45 10.7 0.0 0.45 10.7 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 PRP81586.1 - 1.1 10.1 26.3 5.2 8.0 0.5 7.4 8 0 0 8 8 8 0 Leucine Rich Repeat DUF3855 PF12967.7 PRP81587.1 - 0.063 13.2 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3855) REF PF05755.12 PRP81587.1 - 0.071 12.9 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Sel_put PF04328.13 PRP81587.1 - 0.13 12.3 0.1 0.41 10.7 0.1 1.9 1 0 0 1 1 1 0 Selenoprotein, putative F-box-like PF12937.7 PRP81588.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 PRP81588.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.25 PRP81589.1 - 3e-79 266.1 0.0 4.6e-79 265.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81589.1 - 1.7e-33 116.0 0.0 3.3e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP81589.1 - 0.0089 15.0 0.1 0.0089 15.0 0.1 3.2 2 1 0 2 2 2 1 Haspin like kinase domain BACK PF07707.15 PRP81589.1 - 0.014 15.5 0.5 0.061 13.4 0.1 2.2 2 0 0 2 2 2 0 BTB And C-terminal Kelch Kdo PF06293.14 PRP81589.1 - 0.023 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PRP81589.1 - 0.062 12.4 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 PRP81589.1 - 0.081 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NuA4 PF09340.10 PRP81590.1 - 3.3e-23 81.4 0.3 3.3e-23 81.4 0.3 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 PLAC8 PF04749.17 PRP81590.1 - 8.5e-17 62.0 24.7 1.3e-16 61.3 24.7 1.3 1 0 0 1 1 1 1 PLAC8 family Dynactin_p22 PF07426.11 PRP81590.1 - 0.032 14.1 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 tRNA-synt_2d PF01409.20 PRP81591.1 - 2.8e-51 174.4 2.9 2.2e-50 171.5 2.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 PRP81591.1 - 3.4e-22 78.7 0.0 1.9e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain WD40 PF00400.32 PRP81592.1 - 9.5e-37 124.4 16.6 2.2e-06 28.3 0.1 8.4 7 1 1 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 PRP81592.1 - 6e-12 45.0 11.0 0.00074 18.3 0.3 5.2 2 2 2 5 5 5 4 Nucleoporin Nup120/160 PQQ_3 PF13570.6 PRP81592.1 - 1.7e-05 25.1 1.4 1.5 9.4 0.0 5.3 6 0 0 6 6 6 2 PQQ-like domain WD40_like PF17005.5 PRP81592.1 - 3.6e-05 23.2 3.1 0.15 11.3 0.2 4.1 1 1 1 2 2 2 2 WD40-like domain DUF2835 PF11197.8 PRP81592.1 - 5.5e-05 22.9 0.2 2 8.3 0.0 4.9 6 0 0 6 6 6 1 Protein of unknown function (DUF2835) DUF4278 PF14105.6 PRP81592.1 - 0.0035 17.7 0.3 1.9 9.0 0.1 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4278) ANAPC4_WD40 PF12894.7 PRP81592.1 - 0.0037 17.5 0.2 14 6.1 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP81592.1 - 0.0066 15.2 3.9 1.9 7.2 0.0 4.2 1 1 3 4 4 4 2 Nup133 N terminal like LVIVD PF08309.11 PRP81592.1 - 0.025 13.9 0.1 3.1 7.2 0.0 2.5 2 0 0 2 2 2 0 LVIVD repeat PQQ_2 PF13360.6 PRP81592.1 - 0.054 13.1 1.5 0.35 10.4 0.3 2.4 1 1 1 2 2 2 0 PQQ-like domain DUF5050 PF16472.5 PRP81592.1 - 0.35 10.1 5.7 2.6 7.2 1.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5050) RasGAP PF00616.19 PRP81593.1 - 9.1e-18 64.7 0.0 6.1e-14 52.2 0.0 2.8 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CUE PF02845.16 PRP81594.1 - 1e-06 28.3 0.0 3.1e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 CUE domain LBP_BPI_CETP PF01273.25 PRP81594.1 - 0.00067 19.3 0.0 0.0052 16.4 0.0 2.0 1 1 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Ada3 PF10198.9 PRP81594.1 - 0.0043 17.2 0.4 0.0095 16.1 0.4 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 HTH_8 PF02954.19 PRP81594.1 - 0.037 13.8 0.1 0.16 11.8 0.0 2.2 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family U-box PF04564.15 PRP81596.1 - 2.5e-19 69.2 0.1 8.9e-19 67.4 0.1 2.0 1 0 0 1 1 1 1 U-box domain ATG16 PF08614.11 PRP81596.1 - 0.052 13.8 41.3 0.034 14.4 11.0 3.1 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 PRP81596.1 - 0.97 8.2 43.1 0.0065 15.4 18.4 2.5 2 0 0 2 2 2 0 Spc7 kinetochore protein BPL_LplA_LipB PF03099.19 PRP81597.1 - 5.4e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FlgH PF02107.16 PRP81597.1 - 0.052 13.1 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein Cyclin_C_2 PF16899.5 PRP81598.1 - 0.0087 16.4 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin C-terminal domain GMC_oxred_N PF00732.19 PRP81599.1 - 6e-17 61.9 0.0 1.8e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP81599.1 - 4.6e-12 46.7 0.4 2.7e-11 44.2 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase Flot PF15975.5 PRP81599.1 - 0.0029 17.8 9.0 0.0029 17.8 9.0 2.0 2 0 0 2 2 2 1 Flotillin HAD_2 PF13419.6 PRP81600.1 - 1.3e-25 90.5 0.0 3.8e-16 59.7 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP81600.1 - 2.7e-10 40.9 0.1 1e-08 35.7 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP81600.1 - 0.0085 16.1 0.1 0.019 15.0 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 PRP81600.1 - 0.023 15.1 0.0 0.068 13.6 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ependymin PF00811.18 PRP81601.1 - 0.0012 19.1 0.9 0.0022 18.2 0.9 1.4 1 0 0 1 1 1 1 Ependymin zf-PARP PF00645.18 PRP81603.1 - 6.9e-22 78.1 2.5 6.9e-22 78.1 2.5 2.5 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Glyco_hydro_18 PF00704.28 PRP81603.1 - 2.8e-13 50.3 0.0 5.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP81603.1 - 6.6e-10 39.3 42.2 9.4e-07 29.2 17.7 3.4 4 0 0 4 4 4 2 Chitin recognition protein zf-CCHH PF10283.9 PRP81603.1 - 1.1e-09 38.1 5.3 2e-09 37.2 5.3 1.5 1 0 0 1 1 1 1 PBZ domain CUE PF02845.16 PRP81603.1 - 3.8e-06 26.5 0.0 7.7e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain HUN PF08729.10 PRP81603.1 - 7.3e-05 22.7 3.9 0.00031 20.7 3.9 2.1 1 0 0 1 1 1 1 HPC2 and ubinuclein domain FHA_2 PF17913.1 PRP81603.1 - 0.00013 22.1 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF2393 PF09624.10 PRP81603.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) YhhN PF07947.14 PRP81604.1 - 1.4e-06 28.1 8.8 2.2e-06 27.4 8.8 1.3 1 0 0 1 1 1 1 YhhN family DUF3429 PF11911.8 PRP81604.1 - 0.038 14.3 4.5 0.17 12.2 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF3429) Hpt PF01627.23 PRP81605.1 - 3.9e-07 30.3 0.5 5.5e-07 29.8 0.5 1.2 1 0 0 1 1 1 1 Hpt domain EF-hand_12 PF17901.1 PRP81606.1 - 2.9e-23 82.1 0.8 1.2e-21 77.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand fold domain STATa_Ig PF18214.1 PRP81606.1 - 3e-17 62.8 0.0 3e-17 62.8 0.0 2.1 2 1 0 2 2 2 1 STATa Immunoglobulin-like domain SH2 PF00017.24 PRP81606.1 - 1.3e-08 34.8 0.0 4.3e-08 33.2 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Dict-STAT-coil PF09267.10 PRP81606.1 - 0.0098 16.3 4.6 0.018 15.4 4.6 1.4 1 0 0 1 1 1 1 Dictyostelium STAT, coiled coil Cbl_N3 PF02762.14 PRP81606.1 - 0.021 14.7 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain UPF0270 PF06794.12 PRP81606.1 - 0.083 13.0 1.4 10 6.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) Thioredoxin_6 PF13848.6 PRP81606.1 - 0.12 12.3 1.4 7.6 6.4 0.9 2.5 1 1 1 2 2 2 0 Thioredoxin-like domain BAT2_N PF07001.11 PRP81606.1 - 0.17 12.3 5.1 0.3 11.5 5.1 1.3 1 0 0 1 1 1 0 BAT2 N-terminus Syntaxin-6_N PF09177.11 PRP81606.1 - 0.66 10.6 5.5 11 6.7 0.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ALMT PF11744.8 PRP81606.1 - 2.4 6.9 7.9 2.1 7.1 6.4 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Tubulin PF00091.25 PRP81607.1 - 8.9e-69 231.6 0.0 1.6e-68 230.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PRP81607.1 - 5.4e-40 136.5 0.6 1.7e-39 134.9 0.1 1.9 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PRP81607.1 - 3.3e-05 24.2 1.2 7.2e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PRP81607.1 - 0.0046 16.2 0.8 0.028 13.6 0.0 2.5 3 0 0 3 3 3 1 Tubulin like RPA_interact_C PF14768.6 PRP81607.1 - 0.055 14.0 0.0 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 Replication protein A interacting C-terminal eIF3_N PF09440.10 PRP81608.1 - 9e-28 97.4 4.4 9e-28 97.4 4.4 2.3 3 0 0 3 3 3 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 PRP81608.1 - 5.4e-13 49.4 1.9 8.6e-13 48.7 0.1 2.4 3 0 0 3 3 3 1 PCI domain RasGEF PF00617.19 PRP81610.1 - 3.1e-41 141.5 0.0 1e-40 139.8 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP81610.1 - 0.0098 16.1 0.1 0.14 12.4 0.1 2.4 1 1 0 1 1 1 1 RasGEF N-terminal motif DUF1408 PF07193.11 PRP81610.1 - 0.22 11.7 1.4 0.4 10.8 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1408) IQ PF00612.27 PRP81610.1 - 0.69 9.9 4.8 10 6.2 0.8 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif RPN2_C PF18004.1 PRP81611.1 - 1e-40 139.2 11.8 1e-40 139.2 11.8 1.7 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 PRP81611.1 - 3.4e-31 106.1 23.3 3.5e-06 27.2 0.0 8.8 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 PRP81611.1 - 7.8e-20 71.1 0.6 7.8e-15 55.0 0.0 5.1 4 1 3 7 7 7 3 HEAT repeats HEAT PF02985.22 PRP81611.1 - 8.9e-08 31.8 0.4 0.7 10.3 0.1 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 PRP81611.1 - 1.1e-07 32.2 0.2 0.014 15.9 0.0 5.8 5 0 0 5 5 5 1 HEAT-like repeat ANAPC3 PF12895.7 PRP81611.1 - 0.036 14.3 0.3 0.49 10.7 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin_H_link PF13838.6 PRP81611.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Clathrin-H-link RPN1_RPN2_N PF17781.1 PRP81611.1 - 0.095 12.1 2.6 0.088 12.2 0.6 2.0 2 0 0 2 2 2 0 RPN1/RPN2 N-terminal domain HNH_2 PF13391.6 PRP81614.1 - 0.026 14.6 0.1 0.046 13.9 0.1 1.4 1 0 0 1 1 1 0 HNH endonuclease Laminin_G_3 PF13385.6 PRP81615.1 - 7.1e-18 65.2 2.5 4.2e-17 62.7 2.5 2.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_72 PF03198.14 PRP81615.1 - 2.1e-07 30.5 0.6 2.7e-05 23.6 0.3 2.5 2 0 0 2 2 2 2 Glucanosyltransferase DUF4434 PF14488.6 PRP81615.1 - 0.0012 18.9 0.4 0.0034 17.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4434) Laminin_G_2 PF02210.24 PRP81615.1 - 0.012 16.2 0.1 0.029 15.0 0.1 1.6 1 0 0 1 1 1 0 Laminin G domain Glyco_hydro_99 PF16317.5 PRP81615.1 - 0.027 13.6 0.1 0.027 13.6 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 99 Glyco_hydro_2_C PF02836.17 PRP81615.1 - 0.039 13.1 0.1 0.063 12.4 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain VCBS PF13517.6 PRP81618.1 - 1.7e-06 28.5 8.3 0.1 13.2 0.0 4.8 3 1 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PRP81618.1 - 0.00011 22.3 9.2 0.0097 16.0 0.2 3.5 3 0 0 3 3 3 2 FG-GAP repeat BBS2_Mid PF14783.6 PRP81618.1 - 0.022 14.8 0.1 0.78 9.8 0.0 3.3 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 PRP81618.1 - 0.091 11.8 0.0 0.3 10.1 0.0 1.8 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 PQQ PF01011.21 PRP81618.1 - 0.1 12.6 0.4 0.85 9.7 0.0 2.7 3 0 0 3 3 3 0 PQQ enzyme repeat DUF1077 PF06417.12 PRP81619.1 - 1.1e-38 131.8 3.5 1.8e-38 131.2 2.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1077) Diphtheria_C PF02763.14 PRP81619.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Diphtheria toxin, C domain NYD-SP12_N PF15015.6 PRP81619.1 - 0.16 10.3 0.5 0.28 9.5 0.4 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated, N-terminal Nebulin PF00880.18 PRP81619.1 - 0.29 11.1 1.5 0.49 10.4 1.5 1.3 1 0 0 1 1 1 0 Nebulin repeat PAS PF00989.25 PRP81620.1 - 3.6e-05 23.7 0.0 0.00068 19.6 0.0 2.7 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.7 PRP81620.1 - 0.00044 20.2 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 PRP81620.1 - 0.00058 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 PAS domain RRM_1 PF00076.22 PRP81622.1 - 3.7e-15 55.5 0.0 5.9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TylF PF05711.11 PRP81622.1 - 0.12 11.7 0.1 3.8 6.7 0.0 2.1 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) Esterase_phd PF10503.9 PRP81623.1 - 6.4e-06 25.8 0.1 4.2e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.12 PRP81623.1 - 0.00045 19.0 0.1 0.4 9.3 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 PRP81623.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PRP81623.1 - 0.014 14.9 0.7 0.026 14.0 0.7 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family COX17 PF05051.13 PRP81624.1 - 2e-19 69.7 4.2 2.5e-19 69.3 4.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ank_2 PF12796.7 PRP81625.1 - 1.1e-31 109.2 1.4 4.8e-13 49.5 0.0 4.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) BTB PF00651.31 PRP81625.1 - 2.4e-30 105.0 0.1 4e-20 72.1 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain Ank PF00023.30 PRP81625.1 - 1.4e-28 98.1 8.9 0.00013 22.3 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 PRP81625.1 - 2.8e-26 88.7 2.6 0.00033 20.9 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 PRP81625.1 - 3e-21 75.5 1.6 5.9e-08 33.1 0.0 5.3 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP81625.1 - 8.7e-21 73.7 2.7 0.00049 20.3 0.0 7.0 3 1 4 7 7 7 6 Ankyrin repeats (many copies) DHR-2 PF06920.13 PRP81626.1 - 9.7e-135 450.2 10.8 1.6e-134 449.5 10.8 1.3 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 PRP81626.1 - 1e-41 142.9 1.3 2e-40 138.7 0.8 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF4518 PF15008.6 PRP81627.1 - 0.015 14.5 0.3 0.022 13.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) DUF5463 PF17551.2 PRP81627.1 - 1.6 8.7 5.2 0.34 10.9 1.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5463) Pkinase_Tyr PF07714.17 PRP81628.1 - 1.7e-61 207.8 0.0 1.1e-60 205.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP81628.1 - 1e-59 198.2 140.8 2.3e-06 27.2 6.2 19.7 12 6 9 22 22 22 19 Leucine rich repeat LRR_4 PF12799.7 PRP81628.1 - 7.1e-41 137.5 158.9 3.8e-05 24.0 4.4 23.9 14 8 8 25 25 25 20 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP81628.1 - 2.1e-40 138.8 0.0 1.9e-39 135.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 PRP81628.1 - 0.00015 22.2 0.1 0.08 13.5 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) LRRNT_2 PF08263.12 PRP81628.1 - 0.0077 16.5 1.5 0.011 16.0 0.4 1.9 2 0 0 2 2 1 1 Leucine rich repeat N-terminal domain F-box PF00646.33 PRP81628.1 - 0.0091 15.9 0.1 0.045 13.6 0.1 2.3 1 0 0 1 1 1 1 F-box domain Pkinase_fungal PF17667.1 PRP81628.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ank_4 PF13637.6 PRP81628.1 - 0.042 14.4 5.6 0.69 10.6 0.3 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) LRR_6 PF13516.6 PRP81628.1 - 0.045 13.8 126.2 0.077 13.1 0.7 26.8 31 0 0 31 31 31 0 Leucine Rich repeat Kdo PF06293.14 PRP81628.1 - 0.11 11.8 0.2 0.3 10.4 0.2 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.6 PRP81628.1 - 0.14 12.5 2.0 17 5.8 0.0 4.6 3 1 2 5 5 5 0 Ankyrin repeats (many copies) Pkinase PF00069.25 PRP81630.1 - 2e-41 142.1 0.4 2.4e-41 141.8 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81630.1 - 4e-22 78.7 0.1 4.9e-22 78.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP81630.1 - 4.4e-07 30.1 0.0 0.0013 18.7 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP81630.1 - 1.7e-05 24.3 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP81630.1 - 0.00012 21.0 0.0 0.00021 20.2 0.0 1.2 1 1 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 PRP81630.1 - 0.0094 15.5 0.0 0.012 15.1 0.0 1.3 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 PRP81630.1 - 0.029 13.9 0.2 0.048 13.3 0.2 1.4 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 PRP81630.1 - 0.051 13.2 0.1 0.38 10.3 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MIP PF00230.20 PRP81631.1 - 2.3e-41 142.0 8.0 3.2e-41 141.5 8.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 PRP81631.1 - 1.9e-27 96.3 0.0 2.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81631.1 - 3.5e-10 39.6 0.0 5.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PTPLA PF04387.14 PRP81633.1 - 2.7e-79 264.6 22.9 1.4e-40 138.7 9.0 2.1 1 1 1 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA DUF4501 PF14946.6 PRP81633.1 - 6.7 6.8 7.0 22 5.1 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) ATG27 PF09451.10 PRP81635.1 - 3.2e-18 66.5 0.0 5.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 PRP81635.1 - 2e-09 36.9 0.0 2.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CBM9_1 PF06452.11 PRP81635.1 - 6.6e-08 32.7 0.2 1.3e-07 31.7 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 PRP81635.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding family 9 AAA PF00004.29 PRP81637.1 - 6.3e-97 321.1 0.0 9.4e-49 165.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP81637.1 - 4.1e-27 93.7 10.1 2.7e-13 49.5 0.8 3.6 3 1 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 PRP81637.1 - 7.2e-21 74.2 1.1 3.3e-20 72.1 1.1 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 PRP81637.1 - 1.7e-14 53.9 0.0 9.4e-06 25.5 0.0 2.9 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PRP81637.1 - 1.8e-12 47.9 0.3 0.00081 19.8 0.1 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 PRP81637.1 - 5.9e-12 46.0 0.0 5.3e-06 26.6 0.0 3.2 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PRP81637.1 - 1.7e-11 44.3 0.1 4.8e-06 26.6 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 PRP81637.1 - 4.7e-11 42.3 0.0 9.8e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 PRP81637.1 - 6.3e-11 42.6 0.0 2.9e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PRP81637.1 - 1.1e-10 42.0 0.3 0.039 14.2 0.0 3.9 2 2 2 4 4 3 3 AAA domain TIP49 PF06068.13 PRP81637.1 - 1.3e-08 34.4 0.6 0.0011 18.2 0.0 2.7 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_14 PF13173.6 PRP81637.1 - 2.1e-08 34.3 0.0 0.0024 17.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 PRP81637.1 - 3.1e-07 30.7 0.0 0.0061 16.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 PRP81637.1 - 3.3e-07 29.9 0.1 0.022 14.2 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 PRP81637.1 - 7.1e-07 29.8 0.0 0.056 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 PRP81637.1 - 1e-06 28.6 0.1 0.053 13.2 0.0 3.0 2 1 1 3 3 3 2 IstB-like ATP binding protein Vps4_C PF09336.10 PRP81637.1 - 4.2e-06 26.7 0.0 0.00079 19.4 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 PRP81637.1 - 4.3e-06 26.4 0.0 0.049 13.1 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 PRP81637.1 - 4.4e-06 26.0 0.0 0.03 13.4 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 PRP81637.1 - 5.2e-06 27.0 0.0 0.0058 17.1 0.0 2.9 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 PRP81637.1 - 5.9e-06 26.3 0.0 0.038 13.8 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein ATPase PF06745.13 PRP81637.1 - 7.4e-06 25.5 0.1 1.8 7.9 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_24 PF13479.6 PRP81637.1 - 9.6e-06 25.4 0.0 0.16 11.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 PRP81637.1 - 1.9e-05 24.4 0.3 1.9 8.0 0.0 3.6 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.6 PRP81637.1 - 3e-05 24.5 0.0 0.63 10.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 PRP81637.1 - 3.1e-05 24.3 0.0 0.21 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 PRP81637.1 - 3.4e-05 23.6 0.0 0.44 10.2 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 PRP81637.1 - 4.9e-05 23.3 0.0 0.26 11.3 0.0 3.0 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 PRP81637.1 - 5.6e-05 23.2 1.8 0.21 11.5 0.0 3.3 3 1 0 3 3 3 2 ATPase domain predominantly from Archaea DUF815 PF05673.13 PRP81637.1 - 6.6e-05 22.2 0.0 0.019 14.1 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 PRP81637.1 - 6.7e-05 23.0 0.0 0.4 10.8 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 PRP81637.1 - 0.00012 22.0 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UFD1 PF03152.14 PRP81637.1 - 0.00021 20.8 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NB-ARC PF00931.22 PRP81637.1 - 0.00028 20.2 0.0 0.18 11.0 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain ResIII PF04851.15 PRP81637.1 - 0.00032 20.7 0.0 0.051 13.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.12 PRP81637.1 - 0.00066 19.6 0.1 0.27 11.2 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_3 PF07726.11 PRP81637.1 - 0.00076 19.3 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 PRP81637.1 - 0.00084 18.7 0.1 0.56 9.4 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 PRP81637.1 - 0.00085 18.8 0.1 1.7 8.0 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein Rad17 PF03215.15 PRP81637.1 - 0.00099 19.1 0.0 0.75 9.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Zeta_toxin PF06414.12 PRP81637.1 - 0.0015 17.9 0.0 0.53 9.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 PRP81637.1 - 0.0025 17.7 0.0 2.3 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Molydop_binding PF01568.21 PRP81637.1 - 0.0075 16.3 0.1 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain AAA_19 PF13245.6 PRP81637.1 - 0.0087 16.4 0.8 5.6 7.3 0.2 3.0 2 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 PRP81637.1 - 0.01 15.7 1.3 5.6 6.8 0.0 4.0 4 0 0 4 4 4 0 NTPase AAA_30 PF13604.6 PRP81637.1 - 0.018 14.7 0.3 3.4 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain KAP_NTPase PF07693.14 PRP81637.1 - 0.029 13.6 0.1 1.1 8.5 0.0 3.0 2 2 1 3 3 3 0 KAP family P-loop domain Cytidylate_kin2 PF13189.6 PRP81637.1 - 0.038 14.1 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family SKI PF01202.22 PRP81637.1 - 0.072 13.2 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase TniB PF05621.11 PRP81637.1 - 0.082 12.3 0.1 11 5.4 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein PAS_9 PF13426.7 PRP81637.1 - 0.092 13.0 0.1 0.31 11.3 0.1 1.9 1 0 0 1 1 1 0 PAS domain AFG1_ATPase PF03969.16 PRP81637.1 - 0.11 11.4 0.0 8.2 5.2 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Adeno_IVa2 PF02456.15 PRP81637.1 - 0.17 10.6 0.0 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Ank_4 PF13637.6 PRP81638.1 - 1.7e-14 54.0 0.0 8.7e-09 35.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81638.1 - 4.8e-13 49.5 0.0 8.2e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PRP81638.1 - 6.2e-13 48.6 0.0 6.1e-06 26.4 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 PRP81638.1 - 1.1e-12 46.9 0.0 3.4e-06 27.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP81638.1 - 4.9e-11 42.6 0.1 1.2e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF3718 PF12514.8 PRP81638.1 - 0.011 15.8 0.1 0.037 14.2 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3718) PPR PF01535.20 PRP81639.1 - 3.4e-14 52.0 3.4 1.7e-05 24.7 0.0 5.6 5 0 0 5 5 5 3 PPR repeat PPR_2 PF13041.6 PRP81639.1 - 1.5e-13 50.7 3.6 8.7e-06 25.8 0.2 4.7 3 1 2 5 5 5 3 PPR repeat family PPR_1 PF12854.7 PRP81639.1 - 1e-05 25.1 1.3 0.19 11.5 0.1 3.6 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 PRP81639.1 - 0.00055 20.0 3.9 0.48 10.5 0.2 3.2 2 1 1 3 3 3 2 Pentatricopeptide repeat domain MRP-S27 PF10037.9 PRP81639.1 - 0.0076 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 PPR_long PF17177.4 PRP81639.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP HeH PF12949.7 PRP81639.1 - 0.02 14.6 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Methyltransf_16 PF10294.9 PRP81640.1 - 3.9e-14 52.8 0.0 6.1e-08 32.6 0.0 2.3 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 PRP81640.1 - 0.013 15.4 0.0 0.05 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FAM86 PF14904.6 PRP81640.1 - 0.03 14.4 0.2 0.075 13.1 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function Methyltransf_12 PF08242.12 PRP81640.1 - 0.054 14.2 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PRP81640.1 - 0.066 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 PRP81640.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) RRM_1 PF00076.22 PRP81641.1 - 1.4e-14 53.7 0.1 3.7e-14 52.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3_2 PF07653.17 PRP81641.1 - 0.002 17.8 0.0 0.26 11.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain RRM_7 PF16367.5 PRP81641.1 - 0.0021 18.1 0.1 0.0049 17.0 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 PRP81641.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 PRP81642.1 - 1.5e-13 50.0 0.4 5e-08 32.4 0.1 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP81642.1 - 2.6e-12 45.8 0.3 1.7e-05 24.6 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP81642.1 - 2.2e-10 40.0 3.6 0.0086 15.7 0.0 3.3 3 0 0 3 3 3 3 TPR repeat TPR_17 PF13431.6 PRP81642.1 - 2.3e-07 30.7 0.1 0.039 14.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP81642.1 - 1.2e-06 28.2 0.6 0.00038 20.4 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP81642.1 - 0.00074 20.1 0.3 0.012 16.4 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP81642.1 - 0.0012 19.1 0.1 0.79 10.1 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat NuDC PF16273.5 PRP81642.1 - 0.0021 18.5 17.0 0.0021 18.5 17.0 2.3 2 1 0 2 2 1 1 Nuclear distribution C domain Arm_3 PF16186.5 PRP81642.1 - 0.003 17.1 0.1 0.0078 15.7 0.1 1.7 1 0 0 1 1 1 1 Atypical Arm repeat ANAPC_CDC26 PF10471.9 PRP81642.1 - 0.0042 17.9 1.4 0.0042 17.9 1.4 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 TPR_15 PF13429.6 PRP81642.1 - 0.0046 16.2 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP81642.1 - 0.0082 16.8 0.0 0.053 14.2 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_lid_9 PF17871.1 PRP81642.1 - 0.016 15.1 2.6 0.016 15.1 2.6 2.1 2 0 0 2 2 2 0 AAA lid domain PA28_beta PF02252.18 PRP81642.1 - 0.03 14.0 0.1 1.3 8.7 0.0 2.5 2 1 1 3 3 3 0 Proteasome activator pa28 beta subunit MIT PF04212.18 PRP81642.1 - 0.11 12.6 5.3 0.7 10.0 0.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 PRP81642.1 - 0.15 12.7 0.2 3.7 8.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP81642.1 - 0.34 11.0 1.4 1.9 8.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat baeRF_family3 PF18845.1 PRP81642.1 - 0.8 10.0 0.0 0.8 10.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 Vfa1 PF08432.10 PRP81642.1 - 1.3 9.3 10.6 1.6 9.0 4.8 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 VPS9 PF02204.18 PRP81643.1 - 3.8e-29 100.9 0.1 1.4e-28 99.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain FOP_dimer PF09398.10 PRP81643.1 - 0.027 14.7 0.0 0.086 13.1 0.0 1.8 1 0 0 1 1 1 0 FOP N terminal dimerisation domain ABC_tran PF00005.27 PRP81644.1 - 1.4e-41 142.3 0.3 3.4e-25 89.1 0.0 17.5 6 2 2 9 9 5 2 ABC transporter ABC_tran_Xtn PF12848.7 PRP81644.1 - 2.9e-10 40.0 1.7 2.9e-10 40.0 1.7 26.7 16 8 15 32 32 16 1 ABC transporter AAA_15 PF13175.6 PRP81644.1 - 2.3e-08 34.2 6.3 2.3e-08 34.2 6.3 14.2 2 1 10 12 12 2 1 AAA ATPase domain AAA_21 PF13304.6 PRP81644.1 - 8.5e-06 25.8 0.4 0.0023 17.8 0.2 7.6 7 2 1 9 9 8 3 AAA domain, putative AbiEii toxin, Type IV TA system EzrA PF06160.12 PRP81644.1 - 2.6e-05 22.6 62.2 2.6e-05 22.6 62.2 14.8 2 1 11 15 15 13 2 Septation ring formation regulator, EzrA ATP-synt_ab PF00006.25 PRP81644.1 - 0.00043 20.0 0.0 1.3 8.6 0.0 4.2 3 1 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 PRP81644.1 - 0.00085 19.0 1.4 0.072 12.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain HrpB7 PF09486.10 PRP81644.1 - 0.0029 18.0 19.3 0.0029 18.0 19.3 25.0 2 1 22 26 26 16 1 Bacterial type III secretion protein (HrpB7) MMR_HSR1 PF01926.23 PRP81644.1 - 0.0054 16.8 6.5 0.24 11.5 0.1 5.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase AlaDh_PNT_C PF01262.21 PRP81644.1 - 0.6 9.4 7.1 0.34 10.2 1.0 4.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain RuvB_N PF05496.12 PRP81644.1 - 0.75 9.5 4.1 0.52 10.0 1.1 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain SNF2_N PF00176.23 PRP81645.1 - 1.1e-34 119.7 0.0 3.6e-34 118.0 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 PRP81645.1 - 3.1e-09 37.0 12.8 1e-08 35.4 12.8 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP81645.1 - 1.4e-08 34.5 12.8 3.2e-08 33.3 12.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 PRP81645.1 - 2.6e-07 31.0 0.0 8e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP81645.1 - 9.3e-07 29.0 0.0 9.3e-07 29.0 0.0 3.5 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit zf-rbx1 PF12678.7 PRP81645.1 - 1.5e-06 28.4 8.9 6.1e-06 26.4 8.9 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PRP81645.1 - 7.4e-06 25.7 12.7 2e-05 24.3 12.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP81645.1 - 1.3e-05 24.8 10.6 6.1e-05 22.7 10.6 2.2 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 PRP81645.1 - 3.8e-05 23.5 11.4 0.00012 22.0 11.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PRP81645.1 - 4.3e-05 23.5 8.2 6.7e-05 22.8 6.8 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP81645.1 - 6e-05 22.8 9.1 0.00014 21.6 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 PRP81645.1 - 0.00047 20.0 0.1 0.0091 15.8 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 PRP81645.1 - 0.0028 17.5 10.4 0.0059 16.4 10.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PRP81645.1 - 0.016 15.3 4.5 0.12 12.4 4.3 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger GAGA_bind PF06217.12 PRP81645.1 - 0.053 13.8 14.9 0.26 11.5 7.2 2.6 2 0 0 2 2 2 0 GAGA binding protein-like family zf-Nse PF11789.8 PRP81645.1 - 0.22 11.4 6.8 0.48 10.3 6.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit COX17 PF05051.13 PRP81645.1 - 0.53 10.7 4.2 8.8 6.8 0.0 3.2 3 0 0 3 3 2 0 Cytochrome C oxidase copper chaperone (COX17) zf-RING_6 PF14835.6 PRP81645.1 - 0.87 9.5 3.7 1.8 8.5 3.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 PRP81645.1 - 2.3 8.4 6.6 6.8 6.9 6.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 CDC45 PF02724.14 PRP81645.1 - 2.6 6.2 27.1 2.9 6.1 22.2 2.1 2 0 0 2 2 2 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 PRP81645.1 - 5.4 7.4 21.4 3.6 8.0 13.5 2.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 FGF-BP1 PF06473.12 PRP81645.1 - 7.2 6.4 29.0 1.8 8.4 19.8 2.5 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) DDHD PF02862.17 PRP81645.1 - 7.4 6.7 12.2 5 7.2 6.2 2.4 2 0 0 2 2 2 0 DDHD domain VbhA PF18495.1 PRP81646.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Antitoxin VbhA CSN8_PSD8_EIF3K PF10075.9 PRP81647.1 - 1.4e-24 86.7 0.4 2.1e-24 86.2 0.4 1.3 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 PRP81647.1 - 0.0097 15.3 0.0 0.037 13.4 0.0 1.8 2 0 0 2 2 2 1 SAC3/GANP family PLAC8 PF04749.17 PRP81648.1 - 4.9e-12 46.7 20.6 9.5e-12 45.8 20.6 1.5 1 0 0 1 1 1 1 PLAC8 family AMPK1_CBM PF16561.5 PRP81648.1 - 3.9e-11 43.0 3.0 4.1e-11 42.9 0.2 2.4 3 0 0 3 3 3 1 Glycogen recognition site of AMP-activated protein kinase Filamin PF00630.19 PRP81648.1 - 4.4e-07 30.7 2.4 0.31 11.9 0.1 4.2 2 1 1 3 3 3 3 Filamin/ABP280 repeat Man-6-P_recep PF02157.15 PRP81648.1 - 0.019 14.1 0.0 0.055 12.6 0.0 1.7 2 0 0 2 2 2 0 Mannose-6-phosphate receptor CBM_48 PF02922.18 PRP81648.1 - 0.038 14.3 0.1 0.13 12.6 0.1 1.9 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) PET117 PF15786.5 PRP81648.1 - 0.05 13.9 0.4 0.15 12.4 0.4 1.7 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial Questin_oxidase PF14027.6 PRP81649.1 - 7.1e-73 246.1 0.2 7.1e-73 246.1 0.2 1.6 2 0 0 2 2 2 1 Questin oxidase-like CDP-OH_P_transf PF01066.21 PRP81649.1 - 6.9e-12 46.0 2.5 6.9e-12 46.0 2.5 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase LRR_6 PF13516.6 PRP81650.1 - 3.3e-10 39.2 32.4 0.69 10.1 0.3 10.2 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.7 PRP81650.1 - 4e-08 33.4 22.9 0.07 13.6 0.8 6.7 4 4 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP81650.1 - 1.1e-05 25.3 19.0 1.4 9.7 0.1 9.5 9 1 1 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.6 PRP81650.1 - 0.015 15.1 22.8 4.9 7.0 0.1 6.4 5 2 1 6 6 6 0 Leucine rich repeat LRR_2 PF07723.13 PRP81650.1 - 1.4 9.7 5.9 0.26 12.0 0.2 2.9 3 0 0 3 3 3 0 Leucine Rich Repeat RhoGEF PF00621.20 PRP81651.1 - 1.4e-47 162.3 2.6 2.2e-47 161.6 1.5 1.9 2 0 0 2 2 2 1 RhoGEF domain AAA PF00004.29 PRP81652.1 - 2e-16 60.6 0.0 4.7e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP81652.1 - 6.5e-06 26.6 0.1 4.1e-05 24.0 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PRP81652.1 - 8e-06 26.2 0.0 3.4e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 PRP81652.1 - 0.00047 20.2 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PRP81652.1 - 0.0047 16.7 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PRP81652.1 - 0.011 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 PRP81652.1 - 0.019 15.5 0.1 0.11 13.0 0.0 2.4 3 1 0 3 3 1 0 AAA domain AAA_33 PF13671.6 PRP81652.1 - 0.066 13.4 0.0 0.35 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PRP81652.1 - 0.078 13.4 0.0 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 PRP81652.1 - 0.08 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 PRP81652.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM_lid PF17855.1 PRP81652.1 - 0.13 12.7 0.2 0.31 11.5 0.2 1.6 1 0 0 1 1 1 0 MCM AAA-lid domain zf-4CXXC_R1 PF10497.9 PRP81653.1 - 0.0064 16.7 15.6 0.015 15.5 15.6 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE PF01363.21 PRP81653.1 - 8.9 6.5 23.8 2.3e+02 2.0 23.9 2.5 1 1 0 1 1 1 0 FYVE zinc finger SBF_like PF13593.6 PRP81654.1 - 2.2e-54 184.9 8.9 3.1e-54 184.4 8.9 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 PRP81654.1 - 1.9e-09 37.5 7.2 3.3e-09 36.7 7.2 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family Mem_trans PF03547.18 PRP81654.1 - 0.24 9.7 4.9 0.04 12.3 0.4 1.9 1 1 1 2 2 2 0 Membrane transport protein CIMR PF00878.18 PRP81655.1 - 0.00012 22.2 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 PRP81655.1 - 0.019 14.8 0.1 0.027 14.3 0.1 1.4 1 1 0 1 1 1 0 Autophagy-related protein 27 UCH PF00443.29 PRP81656.1 - 4.2e-43 147.7 1.4 8.2e-43 146.7 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP81656.1 - 2.8e-19 69.9 0.2 1.1e-18 67.9 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 PRP81656.1 - 0.072 12.9 1.9 12 5.8 0.1 2.7 2 0 0 2 2 2 0 UBA-like domain PalH PF08733.10 PRP81657.1 - 0.025 13.6 1.7 0.043 12.8 1.7 1.4 1 0 0 1 1 1 0 PalH/RIM21 DUF2207 PF09972.9 PRP81657.1 - 0.1 11.3 1.6 0.15 10.8 1.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PrgI PF12666.7 PRP81657.1 - 1.9 9.3 6.3 1.2 9.9 2.9 2.1 2 0 0 2 2 2 0 PrgI family protein Ydc2-catalyt PF09159.10 PRP81658.1 - 0.0041 16.9 0.2 0.005 16.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Vitellogenin_N PF01347.22 PRP81658.1 - 0.046 12.1 0.2 0.054 11.9 0.2 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region CSN5_C PF18323.1 PRP81658.1 - 0.055 14.4 0.2 0.13 13.2 0.2 1.6 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF2407_C PF13373.6 PRP81658.1 - 0.069 13.3 0.0 0.091 12.9 0.0 1.4 1 1 0 1 1 1 0 DUF2407 C-terminal domain DUF3021 PF11457.8 PRP81658.1 - 0.072 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) B12D PF06522.11 PRP81658.1 - 0.1 12.4 0.1 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PgaD PF13994.6 PRP81658.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Ribosomal_L22 PF00237.19 PRP81660.1 - 5.4e-22 78.0 1.0 5.4e-22 78.0 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e NosD PF05048.13 PRP81661.1 - 0.18 11.0 37.6 0.094 12.0 8.8 4.6 1 1 3 4 4 4 0 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 PRP81661.1 - 0.99 10.0 0.0 0.99 10.0 0.0 8.8 8 3 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat P2X_receptor PF00864.19 PRP81662.1 - 5.1e-15 55.4 1.5 3.9e-07 29.5 0.1 2.2 2 0 0 2 2 2 2 ATP P2X receptor Actin PF00022.19 PRP81664.1 - 1.5e-151 504.6 0.0 4.9e-151 503.0 0.0 1.6 1 1 0 1 1 1 1 Actin CH PF00307.31 PRP81666.1 - 9.4e-16 58.0 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain MMPL PF03176.15 PRP81666.1 - 0.15 10.9 0.3 0.3 10.0 0.3 1.4 1 0 0 1 1 1 0 MMPL family Secretin_N PF03958.17 PRP81667.1 - 0.093 13.1 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Ribonuc_red_sm PF00268.21 PRP81668.1 - 6.1e-117 390.0 0.2 7.2e-117 389.8 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PRP38 PF03371.15 PRP81668.1 - 0.084 12.7 0.4 0.19 11.6 0.1 1.9 2 1 0 2 2 2 0 PRP38 family A_deaminase PF00962.22 PRP81669.1 - 2.1e-113 379.0 0.1 3.1e-113 378.4 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase PLDc PF00614.22 PRP81671.1 - 8.5e-22 76.4 1.3 2.9e-11 43.1 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PRP81671.1 - 4e-14 52.6 1.0 1.1e-07 31.7 0.1 3.7 3 0 0 3 3 3 2 PLD-like domain PH PF00169.29 PRP81671.1 - 2.7e-11 43.9 3.0 1.2e-10 41.8 0.0 3.4 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 PRP81671.1 - 0.019 15.4 0.2 0.19 12.2 0.1 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain EF-hand_7 PF13499.6 PRP81671.1 - 0.038 14.5 0.1 0.49 10.9 0.1 2.7 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 PRP81671.1 - 0.053 13.1 0.0 0.87 9.3 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 PRP81671.1 - 0.074 13.0 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Metallothio_PEC PF02068.16 PRP81672.1 - 0.73 10.2 34.4 1.6 9.2 34.4 1.6 1 1 0 1 1 1 0 Plant PEC family metallothionein Metallothio_5 PF02067.15 PRP81672.1 - 1.6 8.9 41.1 9.2 6.5 11.0 3.2 1 1 1 2 2 2 0 Metallothionein family 5 Metallothio_2 PF01439.18 PRP81672.1 - 8.5 7.3 41.1 0.52 11.2 15.0 2.3 1 1 1 2 2 2 0 Metallothionein Metallothio PF00131.20 PRP81672.1 - 8.6 6.6 40.2 0.86 9.8 13.9 2.1 1 1 1 2 2 2 0 Metallothionein NAP PF00956.18 PRP81673.1 - 1.7e-69 234.0 7.0 2.3e-69 233.6 7.0 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.8 PRP81673.1 - 0.0054 16.8 0.7 0.012 15.7 0.7 1.5 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 Muted PF14942.6 PRP81673.1 - 0.024 15.0 0.2 0.024 15.0 0.2 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein AATF-Che1 PF13339.6 PRP81673.1 - 0.024 15.3 0.7 0.052 14.2 0.7 1.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor FliD_C PF07195.12 PRP81673.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Gp58 PF07902.11 PRP81673.1 - 0.23 9.7 0.1 0.34 9.1 0.1 1.2 1 0 0 1 1 1 0 gp58-like protein zf-NOSIP PF15906.5 PRP81674.1 - 1.1e-13 51.1 0.2 2.7e-13 49.8 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 PRP81674.1 - 1e-12 48.0 4.2 1e-12 48.0 4.2 3.1 2 1 1 3 3 2 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 PRP81674.1 - 1.5e-10 40.7 18.5 3.9e-07 29.8 8.1 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP81674.1 - 2.4e-08 34.2 18.8 4.8e-06 26.8 7.3 2.5 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 PRP81674.1 - 1.3e-07 31.3 5.6 1.3e-07 31.3 5.6 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PRP81674.1 - 1.6e-07 31.0 20.9 1.9e-05 24.4 9.6 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP81674.1 - 1.9e-07 30.9 8.9 1.9e-07 30.9 8.9 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PRP81674.1 - 2.7e-07 30.5 10.8 0.0017 18.3 1.9 2.9 2 1 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 PRP81674.1 - 3.3e-06 26.9 21.2 0.00041 20.2 9.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PRP81674.1 - 9.3e-05 22.2 6.4 9.3e-05 22.2 6.4 3.0 3 1 0 3 3 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 PRP81674.1 - 0.002 18.2 19.3 0.15 12.3 7.6 3.3 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 PRP81674.1 - 0.0051 16.9 16.4 0.0064 16.6 8.4 2.5 2 0 0 2 2 2 1 zinc RING finger of MSL2 DUF1272 PF06906.11 PRP81674.1 - 0.033 14.3 5.6 0.033 14.3 5.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 PRP81674.1 - 0.31 10.9 9.9 2.7 7.9 2.7 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein FYVE PF01363.21 PRP81674.1 - 1.3 9.2 19.3 1.7 8.8 9.0 3.2 2 2 0 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 PRP81674.1 - 4.7 7.3 21.8 1.6 8.7 10.2 3.5 2 1 1 3 3 3 0 zinc-ribbons GFO_IDH_MocA PF01408.22 PRP81677.1 - 1.3e-11 45.3 0.1 3.9e-11 43.8 0.1 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DnaJ PF00226.31 PRP81678.1 - 3.5e-27 94.3 2.1 3.5e-27 94.3 2.1 1.7 2 0 0 2 2 2 1 DnaJ domain Mito_carr PF00153.27 PRP81678.1 - 4.4e-12 45.8 1.8 7.6e-05 22.6 0.0 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein HSP70 PF00012.20 PRP81679.1 - 3.8e-105 352.4 0.2 4.6e-105 352.1 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP81679.1 - 2.8e-16 59.2 0.1 6.7e-16 58.0 0.1 1.6 1 1 0 1 1 1 1 MreB/Mbl protein StbA PF06406.11 PRP81679.1 - 0.0046 16.2 0.0 0.041 13.1 0.0 2.0 1 1 1 2 2 2 1 StbA protein PilM_2 PF11104.8 PRP81679.1 - 0.086 11.9 0.0 1.6 7.7 0.0 2.2 2 1 0 2 2 2 0 Type IV pilus assembly protein PilM; START PF01852.19 PRP81680.1 - 2.3e-11 43.5 0.0 3.3e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 START domain PilO PF04350.13 PRP81680.1 - 0.06 13.5 0.8 6.4 6.9 0.1 3.0 3 0 0 3 3 3 0 Pilus assembly protein, PilO ECH_1 PF00378.20 PRP81683.1 - 2.1e-37 128.8 0.0 3.1e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP81683.1 - 6.3e-17 62.1 0.0 8.1e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LRR_4 PF12799.7 PRP81684.1 - 1.9e-09 37.6 42.1 0.0073 16.7 0.4 10.5 9 1 2 11 11 11 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP81684.1 - 0.16 12.1 0.0 0.16 12.1 0.0 9.6 10 1 1 11 11 11 0 Leucine Rich repeat SAM_Ste50p PF09235.10 PRP81684.1 - 4.3 7.7 10.9 5.9 7.2 0.1 5.1 5 0 0 5 5 5 0 Ste50p, sterile alpha motif adh_short PF00106.25 PRP81685.1 - 2.3e-32 112.1 0.0 1.5e-24 86.5 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP81685.1 - 8.6e-20 71.3 0.0 8.7e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP81685.1 - 8.4e-13 48.6 0.0 1.3e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PRP81685.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DASH_Duo1 PF08651.10 PRP81685.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 NAD_binding_10 PF13460.6 PRP81685.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Glyco_hydro_47 PF01532.20 PRP81686.1 - 2.8e-151 504.5 0.2 3.3e-151 504.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PROL5-SMR PF15621.6 PRP81686.1 - 0.022 15.3 1.9 0.046 14.2 1.9 1.6 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family DUF4490 PF14892.6 PRP81686.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) TPR_1 PF00515.28 PRP81687.1 - 7.1e-62 202.9 5.6 1e-07 31.5 0.1 11.1 11 0 0 11 11 11 8 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 PRP81687.1 - 7.9e-54 182.8 0.4 5.3e-27 94.4 0.1 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 PRP81687.1 - 7.8e-51 169.5 16.9 3.2e-07 29.9 0.4 10.4 4 2 6 10 10 10 9 TPR repeat TPR_8 PF13181.6 PRP81687.1 - 2.5e-50 164.5 2.5 8.4e-07 28.7 0.1 10.3 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 PRP81687.1 - 9.6e-50 162.7 0.2 1.6e-06 27.7 0.0 11.0 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.6 PRP81687.1 - 9.8e-34 113.3 16.3 1.7e-06 28.0 0.1 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 PRP81687.1 - 9.8e-32 109.1 6.0 1.3e-06 28.6 0.0 8.0 3 3 4 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 PRP81687.1 - 2.6e-31 105.3 1.0 0.0013 18.6 0.0 11.1 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 PRP81687.1 - 4.8e-25 87.9 0.2 5.4e-05 23.6 0.0 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 PRP81687.1 - 3.2e-23 80.8 0.1 0.087 13.5 0.0 10.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 PRP81687.1 - 3.3e-23 80.4 0.0 0.045 14.6 0.0 10.0 4 4 6 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP81687.1 - 2.9e-22 79.0 0.0 0.00023 21.7 0.0 6.9 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 PRP81687.1 - 5.7e-18 64.2 12.5 0.031 14.1 0.0 9.9 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_9 PF13371.6 PRP81687.1 - 2e-15 56.7 0.0 0.028 14.6 0.0 5.3 4 1 0 4 4 4 4 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 PRP81687.1 - 2e-09 37.3 12.8 2.9e-05 23.7 0.5 4.7 3 1 2 5 5 5 2 Est1 DNA/RNA binding domain NARP1 PF12569.8 PRP81687.1 - 2.9e-08 33.1 0.1 0.0093 14.9 0.1 4.0 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 PRP81687.1 - 4.4e-05 23.6 2.6 3 8.1 0.0 5.0 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 PRP81687.1 - 0.00024 21.1 5.6 3.5 7.8 0.0 6.3 8 0 0 8 8 5 1 MIT (microtubule interacting and transport) domain BTAD PF03704.17 PRP81687.1 - 0.00024 21.6 0.1 47 4.4 0.0 4.7 4 1 1 5 5 5 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 PRP81687.1 - 0.00025 21.4 0.1 26 5.8 0.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat RPN7 PF10602.9 PRP81687.1 - 0.0075 16.0 1.2 6.6 6.4 0.0 5.2 5 2 1 6 6 6 0 26S proteasome subunit RPN7 TPR_MalT PF17874.1 PRP81687.1 - 0.0079 15.6 0.2 1.9 7.8 0.0 3.6 2 1 2 4 4 4 1 MalT-like TPR region TPR_20 PF14561.6 PRP81687.1 - 0.0086 16.4 0.1 16 5.9 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 PRP81687.1 - 0.014 14.6 1.5 14 4.8 0.0 4.6 3 1 2 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 PRP81687.1 - 0.018 15.3 0.2 79 3.8 0.0 5.0 4 0 0 4 4 4 0 PPR repeat SNAP PF14938.6 PRP81687.1 - 0.02 14.3 1.0 33 3.8 0.1 3.9 2 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.14 PRP81687.1 - 0.1 12.0 0.0 30 3.9 0.0 3.9 3 1 1 5 5 5 0 Coatomer epsilon subunit NSF PF02071.20 PRP81687.1 - 2.7 9.1 4.3 32 5.9 0.1 4.1 3 0 0 3 3 2 0 Aromatic-di-Alanine (AdAR) repeat FixQ PF05545.11 PRP81688.1 - 0.0037 17.2 0.6 0.0073 16.2 0.6 1.4 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Tetraspanin PF00335.20 PRP81688.1 - 0.005 16.6 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Tetraspanin family PAP_PilO PF06864.12 PRP81688.1 - 0.0059 15.5 0.0 0.57 8.9 0.0 2.1 2 0 0 2 2 2 2 Pilin accessory protein (PilO) SieB PF14163.6 PRP81688.1 - 0.019 14.5 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B Vpu PF00558.19 PRP81688.1 - 0.027 14.3 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 Vpu protein HemX PF04375.14 PRP81688.1 - 0.056 12.7 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Med8 PF10232.9 PRP81689.1 - 1.4e-17 64.0 5.7 1.4e-17 64.0 5.7 3.5 1 1 1 3 3 3 1 Mediator of RNA polymerase II transcription complex subunit 8 Sgf11 PF08209.11 PRP81690.1 - 1e-05 25.0 0.3 1.8e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-BED PF02892.15 PRP81690.1 - 0.064 13.3 0.2 0.18 11.8 0.2 1.8 1 0 0 1 1 1 0 BED zinc finger zf-TRAF PF02176.18 PRP81691.1 - 1.1e-10 42.0 36.5 9.5e-10 39.0 10.4 4.2 2 1 2 4 4 4 3 TRAF-type zinc finger MATH PF00917.26 PRP81691.1 - 5.2e-09 36.3 0.0 4.1e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 MATH domain zf-C3HC4_2 PF13923.6 PRP81691.1 - 5.4e-07 29.3 11.4 5.4e-07 29.3 11.4 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 PRP81691.1 - 1.5e-06 28.5 10.9 1.5e-06 28.5 10.9 3.8 3 1 1 4 4 4 2 TRAF-like zinc-finger zf-C3HC4_3 PF13920.6 PRP81691.1 - 4.9e-05 23.1 8.8 4.9e-05 23.1 8.8 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP81691.1 - 0.00016 21.6 7.0 0.00016 21.6 7.0 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 PRP81691.1 - 0.00031 21.0 9.1 0.00031 21.0 9.1 3.8 2 1 2 4 4 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PRP81691.1 - 0.00049 20.2 10.2 0.00049 20.2 10.2 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Sina PF03145.16 PRP81691.1 - 0.0052 16.7 1.9 0.0052 16.7 1.9 3.6 1 1 3 4 4 4 1 Seven in absentia protein family zf-C3HC4 PF00097.25 PRP81691.1 - 0.0091 15.8 11.1 0.0091 15.8 11.1 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) HAUS2 PF15003.6 PRP81691.1 - 0.044 13.5 0.3 0.074 12.8 0.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 U-box PF04564.15 PRP81691.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 U-box domain CdvA PF18822.1 PRP81691.1 - 0.12 12.3 0.5 0.21 11.4 0.5 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain KxDL PF10241.9 PRP81691.1 - 0.26 11.6 2.5 0.56 10.5 2.5 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DASH_Hsk3 PF08227.11 PRP81692.1 - 7.7 7.0 9.4 6.9 7.1 0.2 3.4 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Glyco_hydro_125 PF06824.11 PRP81693.1 - 4.3e-161 536.4 0.0 4.9e-161 536.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) F-box-like PF12937.7 PRP81694.1 - 0.0016 18.3 0.1 0.0036 17.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF1899 PF08953.11 PRP81695.1 - 5.4e-32 109.5 0.1 4.2e-18 65.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) WD40 PF00400.32 PRP81695.1 - 1.4e-31 108.1 22.6 2.2e-05 25.1 0.3 8.3 8 0 0 8 8 8 5 WD domain, G-beta repeat WD40_4 PF16300.5 PRP81695.1 - 1.9e-27 94.8 7.1 1.2e-15 57.1 0.4 3.0 3 0 0 3 3 3 2 Type of WD40 repeat ANAPC4_WD40 PF12894.7 PRP81695.1 - 7e-19 67.9 2.2 0.00017 21.8 0.1 7.6 3 2 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP81695.1 - 5.8e-06 25.5 0.0 3.9 6.3 0.0 5.2 3 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PRP81695.1 - 0.088 11.3 0.2 1.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain TonB_N PF16031.5 PRP81695.1 - 1.3 9.5 9.5 3.5 8.2 9.5 1.6 1 0 0 1 1 1 0 TonB polyproline region UCR_Fe-S_N PF10399.9 PRP81696.1 - 0.077 12.4 2.0 0.16 11.3 0.4 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Pkinase_Tyr PF07714.17 PRP81697.1 - 8.4e-28 97.4 0.4 1.2e-27 96.8 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP81697.1 - 2e-21 75.5 35.8 1.1e-05 25.0 3.1 6.9 5 1 0 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 PRP81697.1 - 1.1e-17 63.9 47.0 0.00037 20.8 0.7 8.3 6 2 2 8 8 8 6 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP81697.1 - 1.3e-17 64.1 0.1 2e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP81697.1 - 0.00038 20.9 0.0 0.00099 19.6 0.0 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_9 PF14580.6 PRP81697.1 - 0.0055 16.2 4.8 0.27 10.7 0.3 3.8 3 1 1 4 4 4 1 Leucine-rich repeat LRR_1 PF00560.33 PRP81697.1 - 0.018 15.5 29.3 0.62 10.8 0.3 9.0 10 0 0 10 10 10 0 Leucine Rich Repeat IPI_T4 PF11634.8 PRP81697.1 - 0.11 12.5 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 Pkinase_Tyr PF07714.17 PRP81698.1 - 8.6e-23 80.9 2.6 4.5e-21 75.3 2.6 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81698.1 - 2.1e-18 66.6 0.6 1.5e-17 63.9 0.6 2.0 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP81698.1 - 9.9e-10 38.8 3.4 9.9e-10 38.8 3.4 2.1 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif TMEM154 PF15102.6 PRP81698.1 - 0.021 14.7 0.1 0.076 12.9 0.1 1.9 1 0 0 1 1 1 0 TMEM154 protein family Protocadherin PF08374.11 PRP81698.1 - 0.049 13.6 0.4 0.12 12.3 0.4 1.7 1 0 0 1 1 1 0 Protocadherin LRR_4 PF12799.7 PRP81699.1 - 9.7e-20 70.3 59.3 1.3e-05 25.4 1.0 8.5 5 3 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP81699.1 - 2.4e-15 56.0 60.7 6.1e-06 25.9 4.1 8.0 4 2 6 10 10 10 7 Leucine rich repeat LRR_9 PF14580.6 PRP81699.1 - 7e-07 28.9 17.3 0.002 17.7 2.3 4.0 3 1 1 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 PRP81699.1 - 0.014 15.4 15.6 0.55 10.2 1.0 3.7 3 1 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PRP81699.1 - 0.022 15.2 41.4 0.22 12.2 0.1 10.5 11 1 0 11 11 11 0 Leucine Rich Repeat PhoLip_ATPase_C PF16212.5 PRP81700.1 - 0.011 15.4 0.2 0.013 15.3 0.2 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal LRR_4 PF12799.7 PRP81701.1 - 8.3e-32 108.7 114.4 0.00016 22.0 0.6 15.4 10 4 7 17 17 17 17 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP81701.1 - 4e-31 106.6 102.4 1.7e-07 30.9 2.7 13.8 9 4 5 15 15 15 10 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP81701.1 - 8.7e-22 77.6 5.4 1.5e-13 50.6 1.9 3.5 2 1 0 2 2 2 2 Protein tyrosine kinase GPS PF01825.21 PRP81701.1 - 4.2e-19 68.8 15.1 4.7e-09 36.6 3.7 3.2 2 0 0 2 2 2 2 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP81701.1 - 1.5e-12 47.5 3.0 2.5e-07 30.4 0.8 3.2 2 1 0 2 2 2 2 Protein kinase domain LRR_9 PF14580.6 PRP81701.1 - 5e-06 26.1 24.0 0.028 13.9 1.9 6.0 3 2 3 6 6 6 4 Leucine-rich repeat PRIMA1 PF16101.5 PRP81701.1 - 3.2e-05 23.9 0.8 0.17 11.9 0.1 2.5 2 0 0 2 2 2 2 Proline-rich membrane anchor 1 RVP_2 PF08284.11 PRP81701.1 - 0.032 14.0 0.0 0.092 12.5 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease APH_6_hur PF04655.14 PRP81701.1 - 0.037 13.4 1.4 4.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Trep_Strep PF09605.10 PRP81701.1 - 0.14 12.1 1.1 19 5.2 0.1 2.7 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF937 PF06078.11 PRP81701.1 - 0.69 10.5 6.3 2.1 9.0 0.4 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) GRAM PF02893.20 PRP81703.1 - 1.3e-05 25.1 0.4 1.3e-05 25.1 0.4 2.1 2 0 0 2 2 2 1 GRAM domain YabA PF06156.13 PRP81703.1 - 0.0017 19.0 4.8 0.0017 19.0 4.8 5.1 2 1 2 5 5 5 2 Initiation control protein YabA Spectrin PF00435.21 PRP81703.1 - 0.019 15.5 3.1 0.019 15.5 3.1 4.0 1 1 3 4 4 4 0 Spectrin repeat CALCOCO1 PF07888.11 PRP81703.1 - 0.095 11.5 46.2 0.15 10.9 33.8 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HAP1_N PF04849.13 PRP81703.1 - 1 8.5 61.1 0.025 13.8 6.5 3.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region LRR_8 PF13855.6 PRP81705.1 - 3.8e-16 58.6 46.7 3.4e-05 23.5 6.1 6.8 5 1 1 6 6 6 4 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP81705.1 - 1.3e-15 57.4 2.9 6.6e-14 51.8 2.9 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP81705.1 - 4.1e-13 49.3 72.8 0.0014 19.0 8.3 9.4 4 3 7 11 11 11 8 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP81705.1 - 4.4e-12 45.9 0.2 8.5e-11 41.7 0.2 2.6 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP81705.1 - 2.1e-09 37.7 3.7 2.1e-09 37.7 3.7 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_9 PF14580.6 PRP81705.1 - 0.011 15.2 10.9 0.36 10.3 0.9 3.3 2 1 1 3 3 3 0 Leucine-rich repeat PRIMA1 PF16101.5 PRP81705.1 - 0.097 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LRR_8 PF13855.6 PRP81707.1 - 1.7e-08 34.1 13.1 6.3e-07 29.1 5.7 2.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PRP81707.1 - 6.7e-05 23.2 18.0 0.0035 17.7 5.1 3.7 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP81707.1 - 0.098 13.3 11.7 0.26 12.0 0.8 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat PARG_cat PF05028.14 PRP81708.1 - 2.1e-90 303.4 0.0 4.6e-90 302.3 0.0 1.6 2 0 0 2 2 2 1 Poly (ADP-ribose) glycohydrolase (PARG) AMP-binding PF00501.28 PRP81708.1 - 1.4e-48 165.5 0.0 3.7e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 PRP81708.1 - 1.4e-31 109.6 0.0 4.5e-31 107.9 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Kelch_6 PF13964.6 PRP81708.1 - 2.4e-24 84.8 10.2 5.5e-06 26.5 0.0 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PRP81708.1 - 3.1e-23 81.1 10.9 2e-06 27.2 0.1 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PRP81708.1 - 2.4e-20 72.3 10.3 5.6e-05 23.1 0.0 5.8 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP81708.1 - 3e-18 65.4 12.7 9.2e-06 25.5 0.0 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 PRP81708.1 - 6.9e-18 63.9 11.5 2.9e-06 27.0 0.3 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 PRP81708.1 - 2.2e-13 50.1 6.2 3.1e-05 24.1 0.2 5.7 5 0 0 5 5 5 3 Galactose oxidase, central domain PP-binding PF00550.25 PRP81708.1 - 7.8e-09 35.8 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site F-box-like PF12937.7 PRP81708.1 - 0.00023 21.0 0.6 0.00064 19.6 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP81708.1 - 0.001 18.9 0.8 0.0029 17.5 0.8 1.8 1 0 0 1 1 1 1 F-box domain Pro_CA PF00484.19 PRP81709.1 - 4.2e-48 163.6 0.1 5.3e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Aldedh PF00171.22 PRP81710.1 - 6.5e-180 598.6 0.0 7.4e-180 598.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_6 PF12774.7 PRP81711.1 - 1.6e-125 418.4 0.0 6.6e-125 416.4 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PRP81711.1 - 1.5e-101 340.4 0.7 1.5e-101 340.4 0.7 6.1 6 1 2 8 8 7 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 PRP81711.1 - 5.2e-71 238.3 5.0 5.2e-71 238.3 5.0 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 PRP81711.1 - 6.8e-54 182.9 0.0 4.1e-53 180.4 0.0 2.5 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 PRP81711.1 - 1e-43 149.9 1.9 1e-43 149.9 1.9 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 Dynein_heavy PF03028.15 PRP81711.1 - 1.4e-38 131.6 0.1 3.3e-34 117.5 0.0 3.7 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 PRP81711.1 - 2.6e-36 124.9 0.0 7.9e-36 123.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PRP81711.1 - 8.4e-33 113.3 0.0 1.3e-19 70.6 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PRP81711.1 - 4e-31 107.9 1.0 4.7e-27 94.7 0.0 3.8 4 0 0 4 4 3 2 P-loop containing dynein motor region Dynein_C PF18199.1 PRP81711.1 - 2.4e-28 99.3 0.0 2.4e-28 99.3 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 PRP81711.1 - 4.8e-28 98.2 14.1 4.8e-28 98.2 14.1 2.0 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_16 PF13191.6 PRP81711.1 - 2.5e-09 37.7 0.1 0.69 10.3 0.0 5.4 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 PRP81711.1 - 3.8e-06 27.2 5.8 0.018 15.3 0.0 5.5 5 0 0 5 5 4 1 AAA domain AAA PF00004.29 PRP81711.1 - 4.7e-06 27.0 0.1 6.6 7.2 0.0 5.5 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PRP81711.1 - 7.8e-06 26.5 0.0 0.24 11.9 0.0 3.9 2 0 0 2 2 2 2 ABC transporter AAA_30 PF13604.6 PRP81711.1 - 0.00023 20.9 2.3 0.097 12.4 0.0 4.1 5 0 0 5 5 3 1 AAA domain IstB_IS21 PF01695.17 PRP81711.1 - 0.00052 19.8 0.7 1 9.0 0.0 4.3 5 0 0 5 5 4 1 IstB-like ATP binding protein AAA_18 PF13238.6 PRP81711.1 - 0.00063 20.3 0.8 2.2 8.9 0.0 5.1 5 0 0 5 5 4 1 AAA domain T2SSE PF00437.20 PRP81711.1 - 0.0054 15.8 0.1 0.15 11.1 0.0 2.9 2 1 1 3 3 3 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 PRP81711.1 - 0.0098 15.6 0.0 7.4 6.2 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Guanylate_kin PF00625.21 PRP81711.1 - 0.016 14.9 0.1 4.9 6.8 0.0 3.4 2 0 0 2 2 2 0 Guanylate kinase RNA_helicase PF00910.22 PRP81711.1 - 0.017 15.5 0.1 18 5.8 0.0 4.4 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.6 PRP81711.1 - 0.03 14.3 0.2 12 5.9 0.0 4.1 4 0 0 4 4 3 0 AAA domain AAA_lid_1 PF17857.1 PRP81711.1 - 0.037 14.2 0.0 0.16 12.2 0.0 2.2 1 0 0 1 1 1 0 AAA+ lid domain AAA_24 PF13479.6 PRP81711.1 - 0.041 13.6 5.1 1.4 8.6 0.0 4.3 5 0 0 5 5 3 0 AAA domain RsgA_GTPase PF03193.16 PRP81711.1 - 0.042 13.7 0.1 2.7 7.9 0.0 3.4 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 PRP81711.1 - 0.06 13.1 0.1 1.2 8.9 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 PRP81711.1 - 0.075 12.9 0.0 0.075 12.9 0.0 4.3 5 0 0 5 5 2 0 ATPase domain predominantly from Archaea DUF3071 PF11268.8 PRP81711.1 - 0.076 13.1 0.2 0.24 11.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) ATP_bind_1 PF03029.17 PRP81711.1 - 0.1 12.3 0.0 4.9 6.9 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein LPP PF04728.13 PRP81711.1 - 0.12 12.7 0.8 0.8 10.1 0.8 2.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Fer4_NifH PF00142.18 PRP81711.1 - 0.14 11.6 1.1 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBM_15 PF03426.14 PRP81711.1 - 0.17 11.5 0.0 0.45 10.1 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Mg_chelatase PF01078.21 PRP81711.1 - 0.18 11.2 0.7 18 4.6 0.0 3.4 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI FlaC_arch PF05377.11 PRP81711.1 - 0.43 11.0 4.2 5.6 7.4 0.4 4.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Helo_like_N PF17111.5 PRP81711.1 - 0.47 9.8 6.0 0.13 11.6 0.4 3.1 3 0 0 3 3 3 0 Fungal N-terminal domain of STAND proteins DNA_repr_REX1B PF14966.6 PRP81711.1 - 5.6 7.7 7.0 6.7 7.4 0.4 4.1 3 0 0 3 3 3 0 DNA repair REX1-B Filamin PF00630.19 PRP81712.1 - 1.6e-51 173.4 0.0 2.1e-20 73.4 0.0 3.7 3 0 0 3 3 3 3 Filamin/ABP280 repeat RhoGEF PF00621.20 PRP81712.1 - 2.2e-43 148.6 0.0 4.3e-43 147.7 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Invasin_D3 PF09134.10 PRP81712.1 - 3.2e-14 53.0 0.3 0.00027 21.2 0.0 3.8 3 0 0 3 3 3 3 Invasin, domain 3 IQ_SEC7_PH PF16453.5 PRP81712.1 - 1.3e-07 31.7 0.0 3.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 PH domain ubiquitin PF00240.23 PRP81712.1 - 4.3e-07 29.6 0.0 8.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Cadherin_5 PF17892.1 PRP81712.1 - 0.0014 18.6 0.5 0.033 14.2 0.1 2.9 3 0 0 3 3 3 1 Cadherin-like domain PH PF00169.29 PRP81712.1 - 0.012 16.1 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 PH domain IQ PF00612.27 PRP81712.1 - 0.013 15.2 0.3 0.033 14.0 0.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Big_9 PF17963.1 PRP81712.1 - 0.043 14.6 2.9 0.091 13.5 0.2 3.0 3 0 0 3 3 3 0 Bacterial Ig domain DUF5011 PF16403.5 PRP81712.1 - 0.2 11.8 0.8 34 4.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) F-box-like PF12937.7 PRP81713.1 - 2.8e-16 59.1 0.5 4.7e-08 32.8 0.0 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 PRP81713.1 - 1.6e-11 43.7 1.0 2.1e-06 27.5 0.4 2.6 2 0 0 2 2 2 2 F-box domain WD40 PF00400.32 PRP81713.1 - 2.1e-07 31.5 6.7 0.0021 18.8 0.3 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box_4 PF15966.5 PRP81713.1 - 6.3e-06 26.1 0.4 0.0089 15.9 0.0 2.8 2 0 0 2 2 2 2 F-box ANAPC4_WD40 PF12894.7 PRP81713.1 - 1e-05 25.7 0.0 0.014 15.7 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP81713.1 - 0.003 16.4 0.0 1.6 7.4 0.0 3.5 2 1 0 3 3 3 1 Nup133 N terminal like Elongin_A PF06881.11 PRP81713.1 - 0.023 15.2 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.10 PRP81713.1 - 0.042 14.2 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 0 PRANC domain GRIP PF01465.20 PRP81714.1 - 6.4e-14 51.6 0.5 1.9e-13 50.1 0.5 1.9 1 0 0 1 1 1 1 GRIP domain AAA_13 PF13166.6 PRP81714.1 - 0.002 16.9 30.3 0.002 16.9 30.3 4.8 2 2 2 5 5 5 1 AAA domain DUF1769 PF08588.10 PRP81715.1 - 1.9e-16 60.0 0.0 3.7e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Trp_repressor PF01371.19 PRP81716.1 - 0.17 12.1 1.6 0.46 10.6 0.1 2.2 1 1 1 2 2 2 0 Trp repressor protein LAG1-DNAbind PF09271.11 PRP81716.1 - 9.1 6.9 8.3 0.6 10.7 0.4 2.4 2 1 1 3 3 3 0 LAG1, DNA binding Mpv17_PMP22 PF04117.12 PRP81717.1 - 4.1e-20 71.8 0.4 8.2e-20 70.8 0.4 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family TM231 PF10149.9 PRP81717.1 - 0.014 14.8 0.2 0.02 14.3 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 231 NTF2 PF02136.20 PRP81718.1 - 1.6e-24 86.7 0.1 2.5e-24 86.2 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain CDC27 PF09507.10 PRP81718.1 - 3 7.1 22.0 4.5 6.5 22.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ax_dynein_light PF10211.9 PRP81719.1 - 5.7e-10 39.4 13.9 5.7e-10 39.4 13.9 2.8 3 1 0 3 3 3 1 Axonemal dynein light chain RRM_1 PF00076.22 PRP81720.1 - 2e-19 69.2 0.0 2.7e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP81720.1 - 0.0013 18.8 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 PRP81720.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif BSD PF03909.17 PRP81721.1 - 1.6e-15 56.8 0.6 4.3e-15 55.5 0.6 1.8 1 0 0 1 1 1 1 BSD domain YqgF PF14639.6 PRP81721.1 - 0.029 14.2 0.1 0.067 13.0 0.1 1.6 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Ribosomal_S17e PF00833.18 PRP81721.1 - 5.5 6.9 7.9 11 6.0 0.4 2.8 2 1 0 2 2 2 0 Ribosomal S17 RhoGEF PF00621.20 PRP81722.1 - 1.3e-41 142.9 2.5 1.3e-41 142.9 2.5 2.1 2 0 0 2 2 2 1 RhoGEF domain SH2 PF00017.24 PRP81722.1 - 2e-28 98.3 0.0 9.7e-17 60.8 0.0 2.9 2 0 0 2 2 2 2 SH2 domain Methyltransf_11 PF08241.12 PRP81722.1 - 1.3e-20 73.9 0.0 3.5e-20 72.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP81722.1 - 3e-19 69.5 0.0 8.9e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP81722.1 - 3.7e-16 59.4 0.0 8.8e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP81722.1 - 5.3e-14 52.3 0.0 1.4e-13 50.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP81722.1 - 4.1e-12 46.7 0.0 1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cbl_N2 PF02761.14 PRP81722.1 - 2.2e-11 44.3 0.4 3.8e-10 40.3 0.0 3.2 3 1 0 3 3 3 1 CBL proto-oncogene N-terminus, EF hand-like domain Ubie_methyltran PF01209.18 PRP81722.1 - 2.2e-10 40.3 0.0 6.2e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 PRP81722.1 - 2.9e-05 23.8 0.1 0.0001 21.9 0.0 1.9 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Cbl_N3 PF02762.14 PRP81722.1 - 2.9e-05 23.8 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 CBL proto-oncogene N-terminus, SH2-like domain IBP39 PF11422.8 PRP81722.1 - 3.8e-05 23.5 0.0 0.00016 21.5 0.0 2.1 1 0 0 1 1 1 1 Initiator binding protein 39 kDa TehB PF03848.14 PRP81722.1 - 0.00032 20.1 0.0 0.00081 18.9 0.0 1.6 1 0 0 1 1 1 1 Tellurite resistance protein TehB PH PF00169.29 PRP81722.1 - 0.001 19.6 0.1 0.0029 18.1 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 PRP81722.1 - 0.0019 18.0 0.0 0.0059 16.4 0.0 1.9 1 0 0 1 1 1 1 PH domain MTS PF05175.14 PRP81722.1 - 0.003 17.1 0.1 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain IQ_SEC7_PH PF16453.5 PRP81722.1 - 0.0052 16.8 0.0 0.017 15.1 0.0 1.9 1 0 0 1 1 1 1 PH domain SH2_2 PF14633.6 PRP81722.1 - 0.0089 15.5 0.0 4.2 6.7 0.0 2.8 3 0 0 3 3 3 1 SH2 domain tRNA-synt_2e PF02091.15 PRP81722.1 - 0.31 10.3 2.2 0.25 10.5 0.2 1.8 2 0 0 2 2 2 0 Glycyl-tRNA synthetase alpha subunit Thioredoxin PF00085.20 PRP81723.1 - 3.5e-22 78.3 0.7 7.2e-20 70.9 0.9 3.1 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 PRP81723.1 - 1.6e-15 57.5 0.0 3.6e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PRP81723.1 - 0.0021 18.5 0.0 0.25 11.8 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PRP81723.1 - 0.09 13.0 0.1 0.72 10.1 0.0 2.4 3 0 0 3 3 3 0 Thioredoxin-like AhpC-TSA PF00578.21 PRP81723.1 - 0.098 12.6 0.1 2.2 8.2 0.1 2.8 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_8 PF13905.6 PRP81723.1 - 0.14 12.5 0.0 4.4 7.7 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin-like TFIIS_C PF01096.18 PRP81725.1 - 1.4e-18 66.5 8.3 1.4e-18 66.5 8.3 2.8 3 1 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.7 PRP81725.1 - 0.00034 20.6 0.3 0.00034 20.6 0.3 3.0 1 1 0 2 2 2 1 Double zinc ribbon RNA_POL_M_15KD PF02150.16 PRP81725.1 - 0.0036 17.1 0.7 0.0036 17.1 0.7 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit C1_1 PF00130.22 PRP81725.1 - 0.0098 15.8 0.1 0.0098 15.8 0.1 2.6 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.6 PRP81725.1 - 0.019 15.3 7.7 0.13 12.7 2.2 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar FYDLN_acid PF09538.10 PRP81725.1 - 0.019 15.6 1.1 0.019 15.6 1.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.7 PRP81725.1 - 0.025 14.5 4.0 0.025 14.5 4.0 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain CSG2 PF16965.5 PRP81725.1 - 0.039 12.9 0.1 0.05 12.6 0.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator zinc_ribbon_2 PF13240.6 PRP81725.1 - 0.054 13.2 0.0 0.054 13.2 0.0 3.0 3 0 0 3 3 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 PRP81725.1 - 0.22 11.0 0.1 0.22 11.0 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain DUF3797 PF12677.7 PRP81725.1 - 0.6 10.0 7.7 27 4.7 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3797) Nudix_N_2 PF14803.6 PRP81725.1 - 0.63 10.0 0.1 0.63 10.0 0.1 3.9 4 0 0 4 4 4 0 Nudix N-terminal UPF0547 PF10571.9 PRP81725.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Baculo_LEF5_C PF11792.8 PRP81725.1 - 1.1 8.9 8.7 0.18 11.5 4.1 2.1 2 1 1 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Zn-ribbon_8 PF09723.10 PRP81725.1 - 2.6 8.2 14.5 15 5.8 0.0 3.9 3 1 0 3 3 3 0 Zinc ribbon domain RNHCP PF12647.7 PRP81725.1 - 3.4 7.7 9.9 2.3 8.3 3.4 2.5 1 1 1 2 2 2 0 RNHCP domain zf-RING_7 PF02591.15 PRP81725.1 - 4.3 7.6 0.0 4.3 7.6 0.0 3.2 3 1 0 3 3 3 0 C4-type zinc ribbon domain Rpr2 PF04032.16 PRP81725.1 - 9.2 6.6 11.5 1.6e+02 2.6 11.5 2.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain CH PF00307.31 PRP81726.1 - 5.6e-15 55.5 0.1 1.5e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain PH PF00169.29 PRP81726.1 - 4.4e-09 36.8 0.2 1e-08 35.6 0.2 1.6 1 0 0 1 1 1 1 PH domain SBF2 PF12335.8 PRP81726.1 - 0.0015 18.2 0.4 0.0037 16.9 0.4 1.6 1 0 0 1 1 1 1 Myotubularin protein Adaptin_N PF01602.20 PRP81728.1 - 1e-71 242.1 3.9 1.3e-71 241.7 3.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PRP81728.1 - 7.8e-32 110.6 0.2 4e-31 108.2 0.0 2.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PRP81728.1 - 4.6e-07 30.1 0.0 7.4e-05 23.1 0.0 3.0 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 PRP81728.1 - 4.7e-07 29.5 0.0 0.0017 18.5 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Spatacsin_C PF14649.6 PRP81729.1 - 6.5e-72 242.2 0.9 1.3e-71 241.2 0.9 1.5 1 0 0 1 1 1 1 Spatacsin C-terminus Glyco_hydro_72 PF03198.14 PRP81730.1 - 2.1e-99 332.8 4.9 3.2e-99 332.2 4.9 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 PRP81730.1 - 7.5e-10 39.4 9.8 8.7e-10 39.1 8.2 2.0 1 1 0 1 1 1 1 X8 domain Inhibitor_I9 PF05922.16 PRP81733.1 - 1e-07 32.5 2.0 2.3e-07 31.4 2.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 TPD PF14811.6 PRP81733.1 - 0.0047 16.8 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif Pkinase PF00069.25 PRP81734.1 - 1.4e-66 224.6 0.1 3.3e-66 223.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81734.1 - 2.3e-30 105.7 0.0 8.9e-30 103.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP81734.1 - 0.00018 20.9 0.0 0.0026 17.1 0.0 2.3 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 PRP81734.1 - 0.0007 18.7 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 PRP81734.1 - 0.0024 17.8 0.0 0.017 15.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP81734.1 - 0.0042 16.7 1.1 0.0074 15.9 0.3 1.8 1 1 0 2 2 2 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PRP81734.1 - 0.0044 16.0 3.8 0.011 14.7 3.7 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Gp58 PF07902.11 PRP81734.1 - 0.11 10.8 4.1 0.19 10.0 4.1 1.3 1 0 0 1 1 1 0 gp58-like protein DUF5364 PF17322.2 PRP81734.1 - 1.4 9.2 7.5 2.3 8.5 7.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5364) X8 PF07983.13 PRP81735.1 - 2.2e-12 47.5 8.5 2.2e-12 47.5 8.5 2.5 2 1 0 2 2 2 1 X8 domain Collagen PF01391.18 PRP81735.1 - 9.6e-06 25.3 21.4 9.6e-06 25.3 21.4 2.3 2 1 0 2 2 2 1 Collagen triple helix repeat (20 copies) Methyltr_RsmF_N PF17125.5 PRP81736.1 - 0.11 13.0 0.1 0.63 10.6 0.1 2.3 3 0 0 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF PRMT5 PF05185.16 PRP81737.1 - 0.0057 16.5 0.6 0.011 15.6 0.6 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Surp PF01805.20 PRP81740.1 - 1.6e-13 50.4 0.2 4.2e-13 49.1 0.2 1.8 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 PRP81740.1 - 0.0029 18.4 0.0 0.013 16.3 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase II-binding domain. ATP11 PF06644.11 PRP81740.1 - 1.2 8.8 5.2 0.19 11.5 0.7 1.8 2 0 0 2 2 2 0 ATP11 protein Med12 PF09497.10 PRP81741.1 - 5.8e-19 68.1 0.0 1.7e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 PRP81741.1 - 9.7e-07 28.0 2.9 9.1e-06 24.8 2.9 2.4 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain NDUFA12 PF05071.16 PRP81741.1 - 0.13 13.2 0.7 2.2 9.2 0.0 2.7 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 Ribosomal_L28 PF00830.19 PRP81742.1 - 3.1e-16 59.3 0.1 6.6e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L28 family Pentapeptide PF00805.22 PRP81743.1 - 2.1e-29 100.7 30.6 3.6e-11 42.5 2.1 4.3 3 1 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 PRP81743.1 - 6.3e-20 71.1 10.9 4.9e-12 45.8 0.8 3.2 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) MIT PF04212.18 PRP81743.1 - 1.9e-11 43.9 1.3 3.2e-11 43.1 0.0 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Pentapeptide_3 PF13576.6 PRP81743.1 - 1.6e-10 41.0 3.1 0.00058 20.0 0.1 4.0 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 PRP81743.1 - 4.7e-05 23.6 0.0 0.00016 21.9 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain EF-hand_1 PF00036.32 PRP81744.1 - 1.9e-23 80.2 0.1 7.6e-08 31.4 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PRP81744.1 - 4.5e-23 81.5 0.2 9.8e-16 58.0 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP81744.1 - 3.9e-21 73.1 0.6 6.4e-08 31.9 0.1 4.0 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 PRP81744.1 - 2.2e-15 56.2 0.2 2.5e-10 40.1 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP81744.1 - 3e-14 51.8 1.5 0.00023 20.5 0.1 3.6 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 PRP81744.1 - 4.8e-11 42.8 0.0 2e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 PRP81744.1 - 4e-05 23.9 0.0 0.0005 20.4 0.0 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PRP81744.1 - 0.004 17.3 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 Dockerin type I domain EF-hand_4 PF12763.7 PRP81744.1 - 0.0056 16.6 0.0 0.71 9.9 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 PRP81744.1 - 0.0081 16.1 0.0 0.65 9.9 0.0 2.8 2 1 1 3 3 3 1 Caleosin related protein DUF5580 PF17743.1 PRP81744.1 - 0.016 13.8 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 PRP81744.1 - 0.016 15.5 0.1 2.8 8.3 0.0 2.8 2 1 0 2 2 2 0 EF-hand domain RuvA_C PF07499.13 PRP81744.1 - 0.03 14.8 0.7 0.81 10.2 0.0 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain TerB PF05099.13 PRP81744.1 - 0.057 13.4 0.4 0.33 10.9 0.0 2.2 1 1 0 2 2 2 0 Tellurite resistance protein TerB RST PF12174.8 PRP81744.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain FAD_binding_3 PF01494.19 PRP81745.1 - 1.1e-23 84.1 0.8 1e-11 44.7 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain UbiA PF01040.18 PRP81745.1 - 6e-22 78.2 8.1 6e-22 78.2 8.1 1.6 2 0 0 2 2 2 1 UbiA prenyltransferase family DAO PF01266.24 PRP81745.1 - 0.00025 20.7 3.0 0.0014 18.3 0.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP81745.1 - 0.037 13.3 0.0 0.052 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP81745.1 - 0.11 12.7 0.9 0.21 11.8 0.1 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 PRP81745.1 - 0.14 11.0 0.1 0.22 10.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Siva PF05458.12 PRP81745.1 - 0.2 11.4 0.6 0.33 10.6 0.6 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Pkinase_Tyr PF07714.17 PRP81746.1 - 5.2e-143 474.9 0.2 1.5e-73 247.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP81746.1 - 8.7e-85 284.3 0.0 1.8e-42 145.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 PRP81746.1 - 3.1e-10 39.7 41.8 0.00062 19.5 2.1 7.2 4 2 3 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 PRP81746.1 - 7.1e-09 35.8 48.6 0.00025 21.3 6.8 9.1 7 3 2 9 9 9 4 Leucine Rich repeats (2 copies) EphA2_TM PF14575.6 PRP81746.1 - 0.00017 22.4 1.1 0.39 11.6 0.0 3.1 3 0 0 3 3 3 2 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 PRP81746.1 - 0.0013 18.2 0.4 0.004 16.5 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP81746.1 - 0.0015 17.4 0.1 0.028 13.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase LapA_dom PF06305.11 PRP81746.1 - 0.059 13.2 3.7 4.4 7.2 0.3 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Nodulin_late PF07127.11 PRP81746.1 - 0.14 12.5 3.0 0.55 10.6 3.0 2.1 1 0 0 1 1 1 0 Late nodulin protein LapD_MoxY_N PF16448.5 PRP81746.1 - 0.19 11.6 0.0 0.53 10.2 0.0 1.7 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain LRR_9 PF14580.6 PRP81746.1 - 1.4 8.4 2.8 1.2 8.6 0.9 1.9 2 0 0 2 2 2 0 Leucine-rich repeat SKG6 PF08693.10 PRP81746.1 - 4.3 6.8 23.5 7.4 6.1 10.7 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain LRR_8 PF13855.6 PRP81748.1 - 8.9e-14 51.0 20.8 4.7e-07 29.5 5.6 3.1 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PRP81748.1 - 3.6e-09 36.7 22.3 7.5e-05 23.0 0.8 3.6 1 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP81748.1 - 5e-09 35.5 16.6 0.18 12.5 0.1 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP81748.1 - 5.5e-06 26.0 24.2 0.1 12.7 0.4 5.9 6 0 0 6 6 6 3 Leucine Rich repeat LRRNT_2 PF08263.12 PRP81748.1 - 0.0017 18.6 1.1 0.004 17.4 1.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.6 PRP81748.1 - 0.17 11.3 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Metallophos PF00149.28 PRP81750.1 - 1.6e-12 48.4 0.0 2.8e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PRP81750.1 - 0.00011 22.5 0.0 0.001 19.3 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DOT1 PF08123.13 PRP81751.1 - 0.06 12.9 0.5 0.24 10.9 0.5 1.9 1 1 0 1 1 1 0 Histone methylation protein DOT1 GRDP-like PF07173.12 PRP81752.1 - 3e-28 99.3 5.7 1e-16 61.9 0.0 3.1 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like MRP-S26 PF14943.6 PRP81752.1 - 0.13 12.1 1.3 0.24 11.3 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 HDV_ag PF01517.18 PRP81753.1 - 0.014 15.2 5.3 0.021 14.6 5.3 1.2 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen YhzD PF14120.6 PRP81753.1 - 0.22 11.6 0.9 0.48 10.6 0.9 1.5 1 0 0 1 1 1 0 YhzD-like protein Guanylate_cyc PF00211.20 PRP81754.1 - 2e-86 288.3 0.3 1.5e-44 151.8 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 PRP81754.1 - 4.6e-52 176.9 0.0 8.5e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81754.1 - 8.4e-50 169.6 0.0 1.4e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 PRP81754.1 - 1.1e-19 70.8 0.6 2.8e-19 69.5 0.6 1.8 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 PRP81754.1 - 3.6e-11 43.0 0.1 2.9e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 SH2 domain HNOBA PF07701.14 PRP81754.1 - 0.0024 17.4 0.2 0.045 13.2 0.1 2.5 2 0 0 2 2 2 1 Heme NO binding associated PH_8 PF15409.6 PRP81754.1 - 0.0036 17.5 0.1 0.011 16.0 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain AC_N PF16214.5 PRP81754.1 - 0.012 14.7 3.5 0.023 13.8 3.5 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region PH_11 PF15413.6 PRP81754.1 - 0.02 15.3 0.9 0.059 13.8 0.9 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 PRP81754.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 PRP81755.1 - 1.2e-75 254.2 0.0 1.7e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP81755.1 - 2.6e-69 228.9 127.6 1.3e-10 40.9 7.1 22.9 13 7 9 24 24 24 20 Leucine rich repeat LRR_4 PF12799.7 PRP81755.1 - 7.5e-69 226.5 137.5 3.2e-06 27.4 3.3 25.2 19 4 7 28 28 27 22 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP81755.1 - 1.6e-51 175.2 0.0 3.9e-51 174.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain LRR_6 PF13516.6 PRP81755.1 - 3.4e-24 82.8 117.8 0.062 13.4 0.2 34.5 37 0 0 37 37 37 7 Leucine Rich repeat LRR_1 PF00560.33 PRP81755.1 - 1.5e-09 37.1 112.1 0.16 12.6 0.3 33.0 40 3 0 40 40 35 2 Leucine Rich Repeat Kdo PF06293.14 PRP81755.1 - 0.00072 19.0 0.0 0.0021 17.4 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP81755.1 - 0.0046 15.8 0.9 0.0079 15.0 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP81755.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_9 PF14580.6 PRP81755.1 - 0.049 13.1 29.2 0.89 9.0 5.3 7.1 5 2 1 6 6 6 0 Leucine-rich repeat Amnionless PF14828.6 PRP81755.1 - 0.099 11.5 0.5 0.22 10.3 0.5 1.5 1 0 0 1 1 1 0 Amnionless DUF347 PF03988.12 PRP81755.1 - 0.34 11.1 3.5 6 7.1 0.6 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) LRRNT_2 PF08263.12 PRP81755.1 - 3.5 8.0 12.8 0.22 11.9 6.9 2.1 2 0 0 2 2 1 0 Leucine rich repeat N-terminal domain DUF1254 PF06863.12 PRP81755.1 - 3.8 7.6 7.1 2.7 8.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1254) NDUFA12 PF05071.16 PRP81756.1 - 5.9e-22 78.3 0.1 9.8e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Aldose_epim PF01263.20 PRP81757.1 - 2.1e-62 211.2 0.0 2.6e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase_Tyr PF07714.17 PRP81758.1 - 3.2e-58 197.0 0.0 5.9e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81758.1 - 2.8e-44 151.4 0.0 5.1e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP81758.1 - 0.079 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PRP81759.1 - 1.7e-72 243.8 0.0 2.4e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81759.1 - 2e-48 165.1 0.0 2.9e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP81759.1 - 2.9e-41 138.8 113.0 1.3e-06 28.6 1.2 18.4 9 5 12 22 22 22 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP81759.1 - 7.2e-41 137.8 107.2 3.4e-10 39.5 0.8 15.7 11 5 4 16 16 16 11 Leucine rich repeat LRR_6 PF13516.6 PRP81759.1 - 8.1e-13 47.3 66.9 0.17 12.0 0.1 20.2 22 0 0 22 22 21 4 Leucine Rich repeat LRR_1 PF00560.33 PRP81759.1 - 2.1e-11 42.7 79.5 0.26 12.0 0.1 24.7 26 3 2 28 28 24 2 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP81759.1 - 0.0024 16.7 0.2 0.0036 16.1 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP81759.1 - 0.0028 17.0 0.2 0.0061 15.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP81759.1 - 0.004 16.5 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SIT PF15330.6 PRP81759.1 - 0.0061 17.0 0.1 0.028 14.9 0.1 2.0 2 0 0 2 2 2 1 SHP2-interacting transmembrane adaptor protein, SIT Amnionless PF14828.6 PRP81759.1 - 0.0073 15.2 0.4 0.012 14.5 0.4 1.2 1 0 0 1 1 1 1 Amnionless DUF1180 PF06679.12 PRP81759.1 - 0.013 15.9 2.0 0.024 15.0 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TMEM154 PF15102.6 PRP81759.1 - 0.023 14.6 1.8 0.046 13.6 1.8 1.4 1 0 0 1 1 1 0 TMEM154 protein family LRR_5 PF13306.6 PRP81759.1 - 0.027 14.4 5.3 1.4 8.9 0.5 4.4 3 1 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) Podoplanin PF05808.11 PRP81759.1 - 0.027 14.6 5.9 0.046 13.8 5.9 1.3 1 0 0 1 1 1 0 Podoplanin Stevor PF17410.2 PRP81759.1 - 0.03 13.9 0.8 0.059 12.9 0.8 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 PRP81759.1 - 0.074 12.5 4.8 0.14 11.6 4.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RIFIN PF02009.16 PRP81759.1 - 0.23 11.3 1.0 0.44 10.4 1.0 1.4 1 0 0 1 1 1 0 Rifin Yip1 PF04893.17 PRP81759.1 - 0.44 10.2 4.0 0.69 9.6 0.6 2.2 2 0 0 2 2 2 0 Yip1 domain Adeno_E3_CR2 PF02439.15 PRP81759.1 - 0.67 9.8 3.7 1.3 8.9 3.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_9 PF14580.6 PRP81759.1 - 0.71 9.3 8.6 2 7.9 0.2 4.4 3 2 2 5 5 5 0 Leucine-rich repeat DUF836 PF05768.14 PRP81761.1 - 2.8e-13 50.1 0.1 6e-13 49.0 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 PRP81761.1 - 0.014 15.6 0.1 0.026 14.7 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_3 PF13192.6 PRP81761.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain Ribosomal_L5e PF17144.4 PRP81762.1 - 1.7e-81 272.0 0.4 3.6e-81 271.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 PRP81762.1 - 1.9e-31 108.8 0.8 1.9e-31 108.8 0.8 2.4 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region Aldedh PF00171.22 PRP81762.1 - 7.4e-07 28.0 0.0 1.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SH3_9 PF14604.6 PRP81763.1 - 1.1e-08 34.7 0.1 2.2e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP81763.1 - 2.1e-06 27.3 0.3 5.9e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 SH3 domain Lzipper-MIP1 PF14389.6 PRP81763.1 - 1.2 9.5 12.2 3.1 8.1 3.5 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Tweety PF04906.13 PRP81763.1 - 5.6 5.5 6.3 1.5 7.4 1.9 1.9 1 1 1 2 2 2 0 Tweety DUF1664 PF07889.12 PRP81763.1 - 6.4 6.8 13.0 2.9 8.0 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ADP_PFK_GK PF04587.15 PRP81764.1 - 2.1e-110 369.3 0.0 5.9e-110 367.8 0.0 1.6 1 1 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region B_solenoid_dext PF18841.1 PRP81764.1 - 0.44 10.9 0.1 0.44 10.9 0.1 1.8 2 0 0 2 2 2 0 Beta solenoid repeat from Dextranase HATPase_c PF02518.26 PRP81765.1 - 8.9e-26 90.6 3.1 9.7e-26 90.5 1.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP81765.1 - 8.2e-23 80.7 0.6 8.2e-23 80.7 0.6 2.3 3 0 0 3 3 3 1 Response regulator receiver domain PHY PF00360.20 PRP81765.1 - 3.4e-20 72.1 0.0 6.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HisKA PF00512.25 PRP81765.1 - 5.8e-16 58.3 0.6 1.4e-15 57.1 0.6 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 PRP81765.1 - 1.4e-14 54.9 0.0 2.9e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 PRP81765.1 - 1.3e-08 35.5 0.0 2.3e-07 31.4 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 PRP81765.1 - 0.0021 18.3 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 PRP81765.1 - 0.072 13.1 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 PRP81765.1 - 0.15 12.4 0.0 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 PAS fold Sds3 PF08598.11 PRP81767.1 - 0.014 15.4 0.9 0.014 15.4 0.9 1.1 1 0 0 1 1 1 0 Sds3-like Tfb5 PF06331.12 PRP81767.1 - 0.079 12.9 0.1 0.099 12.6 0.1 1.2 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 DUF1556 PF07590.11 PRP81768.1 - 0.0028 17.9 0.1 0.0065 16.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1556) TPR_14 PF13428.6 PRP81769.1 - 2.4e-14 52.8 15.1 0.091 13.6 1.7 9.0 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP81769.1 - 1.2e-12 48.1 1.1 1.5 9.4 0.1 8.0 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 PRP81769.1 - 4.6e-08 33.6 3.1 0.15 12.7 0.0 5.9 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP81769.1 - 4.3e-06 26.4 16.6 0.4 10.9 0.1 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP81769.1 - 7.5e-06 26.0 0.0 0.074 13.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP81769.1 - 1.1e-05 25.2 1.1 1.2 9.5 0.0 5.5 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP81769.1 - 0.0085 15.9 6.9 19 5.3 0.5 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP81769.1 - 0.067 13.5 13.3 21 5.5 0.1 6.4 9 1 0 9 9 9 0 Tetratricopeptide repeat MIT PF04212.18 PRP81769.1 - 0.21 11.7 4.1 18 5.5 0.0 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 PRP81769.1 - 0.23 12.2 9.8 1.6e+02 3.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4398 PF14346.6 PRP81769.1 - 5.8 7.6 9.3 26 5.5 0.5 4.4 5 0 0 5 5 4 0 Domain of unknown function (DUF4398) DAP_B PF07930.12 PRP81770.1 - 0.095 12.7 0.8 0.11 12.4 0.8 1.1 1 0 0 1 1 1 0 D-aminopeptidase, domain B zf-C4H2 PF10146.9 PRP81770.1 - 1.1 9.5 4.5 1.4 9.2 4.5 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein LRR_9 PF14580.6 PRP81771.1 - 8e-17 61.3 14.6 4.6e-16 58.8 3.8 3.4 1 1 3 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.7 PRP81771.1 - 3e-13 49.7 21.7 4.6e-07 30.1 1.4 4.6 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP81771.1 - 6.1e-11 41.9 17.0 2.5e-06 27.2 4.3 3.9 1 1 1 3 3 3 3 Leucine rich repeat Ribosomal_L9_N PF01281.19 PRP81772.1 - 4.5e-15 54.9 0.1 7.6e-15 54.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 PRP81772.1 - 0.085 13.3 0.0 0.48 10.9 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain Histone PF00125.24 PRP81773.1 - 4.7e-07 30.2 0.0 9.2e-05 22.8 0.0 2.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 F-box PF00646.33 PRP81773.1 - 0.0048 16.7 0.3 0.046 13.6 0.1 2.7 2 0 0 2 2 2 1 F-box domain Ank_4 PF13637.6 PRP81773.1 - 0.01 16.4 0.0 0.029 15.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81773.1 - 0.017 15.7 0.0 0.053 14.1 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) F-box-like PF12937.7 PRP81773.1 - 0.11 12.4 2.4 0.12 12.3 0.4 2.2 2 0 0 2 2 2 0 F-box-like CBFD_NFYB_HMF PF00808.23 PRP81773.1 - 0.32 11.3 1.2 2 8.8 0.0 2.8 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone VCBS PF13517.6 PRP81775.1 - 0.00029 21.3 33.8 13 6.5 0.1 14.0 15 0 0 15 15 15 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Cadherin_5 PF17892.1 PRP81775.1 - 0.00046 20.1 6.6 0.00051 20.0 0.6 4.3 2 0 0 2 2 2 1 Cadherin-like domain Carmo_coat_C PF08462.10 PRP81775.1 - 8.2 6.6 8.0 43 4.3 0.0 5.6 6 0 0 6 6 6 0 Carmovirus coat protein RRM_1 PF00076.22 PRP81778.1 - 1e-17 63.7 0.1 2.3e-17 62.6 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP81778.1 - 1.3e-07 31.2 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Viral_Beta_CD PF04530.12 PRP81778.1 - 0.06 13.7 0.0 0.074 13.4 0.0 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family WD40 PF00400.32 PRP81779.1 - 9e-31 105.5 29.2 1.2e-06 29.1 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 PRP81779.1 - 4e-10 39.0 5.6 0.0016 17.2 0.0 5.0 3 1 2 5 5 5 3 Nucleoporin Nup120/160 zf-C3HC4_2 PF13923.6 PRP81779.1 - 7.6e-10 38.5 11.3 3.7e-09 36.3 11.1 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP81779.1 - 2.3e-08 33.7 8.8 6.3e-08 32.4 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP81779.1 - 3.9e-08 33.0 12.9 3.9e-08 33.0 12.9 2.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP81779.1 - 1e-07 31.8 12.3 4.9e-07 29.7 11.7 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP81779.1 - 6.7e-07 29.2 11.8 1.7e-06 27.9 11.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 PRP81779.1 - 1.2e-06 28.7 11.8 1.2e-06 28.7 11.8 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PRP81779.1 - 1.1e-05 25.5 13.5 6.5e-05 23.0 13.5 2.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PRP81779.1 - 4.3e-05 23.3 5.8 4.3e-05 23.3 5.8 1.8 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 PRP81779.1 - 5.6e-05 22.9 18.9 0.00014 21.7 13.2 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 Nucleoporin_N PF08801.11 PRP81779.1 - 0.002 17.0 0.7 0.52 9.0 0.1 3.7 2 1 2 4 4 4 1 Nup133 N terminal like zf-Nse PF11789.8 PRP81779.1 - 0.0088 15.8 9.1 0.021 14.6 9.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit baeRF_family3 PF18845.1 PRP81779.1 - 0.0099 16.2 0.0 6.4 7.0 0.0 2.5 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 3 BBS2_Mid PF14783.6 PRP81779.1 - 0.019 15.0 0.0 17 5.5 0.0 4.0 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region zf-rbx1 PF12678.7 PRP81779.1 - 0.019 15.2 11.5 0.1 12.9 9.5 3.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain DUF4795 PF16043.5 PRP81779.1 - 0.032 13.8 0.5 0.057 13.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) U-box PF04564.15 PRP81779.1 - 0.033 14.4 0.1 0.033 14.4 0.1 2.5 3 0 0 3 3 3 0 U-box domain zf-RING_4 PF14570.6 PRP81779.1 - 0.15 11.9 11.4 3.9 7.3 11.5 2.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 PRP81779.1 - 0.29 11.0 10.0 1.6 8.7 10.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 PRP81779.1 - 0.39 11.2 3.5 8.1 7.0 0.9 3.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 PRP81779.1 - 1.1 9.4 8.9 0.87 9.7 5.6 2.6 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 PRP81779.1 - 1.2 9.2 8.0 3.6 7.7 8.0 1.9 1 0 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 PRP81779.1 - 2 8.2 13.2 0.34 10.7 8.0 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C2H2_9 PF16293.5 PRP81779.1 - 3 7.8 5.0 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Cadherin_5 PF17892.1 PRP81780.1 - 0.00026 20.9 4.0 0.00071 19.5 0.1 3.8 2 0 0 2 2 2 1 Cadherin-like domain PaaX PF07848.12 PRP81780.1 - 0.00058 20.0 4.2 8.7 6.6 0.1 5.4 5 0 0 5 5 5 3 PaaX-like protein Carmo_coat_C PF08462.10 PRP81780.1 - 0.0068 16.5 4.5 2 8.6 0.0 6.4 5 0 0 5 5 5 1 Carmovirus coat protein Rap_GAP PF02145.15 PRP81782.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP AhpC-TSA_2 PF13911.6 PRP81782.1 - 0.00049 20.2 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 PRP81782.1 - 0.0009 19.2 0.0 0.0026 17.7 0.0 1.8 1 0 0 1 1 1 1 AhpC/TSA family 2-Hacid_dh_C PF02826.19 PRP81783.1 - 2.7e-57 193.0 0.0 6.8e-57 191.7 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PRP81783.1 - 5.5e-32 110.2 0.0 6.6e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PRP81783.1 - 0.00011 22.5 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 PRP81783.1 - 0.0053 17.3 0.0 0.019 15.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 PRP81783.1 - 0.013 15.7 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 PRP81783.1 - 0.021 14.9 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3102 PF11300.8 PRP81783.1 - 0.085 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) XdhC_C PF13478.6 PRP81783.1 - 0.15 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain RRM_1 PF00076.22 PRP81784.1 - 8.2e-13 48.0 0.0 2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 PRP81784.1 - 0.0041 16.7 0.0 0.016 14.8 0.0 2.0 1 0 0 1 1 1 1 Sporulation protein family 7 DUF131 PF01998.17 PRP81784.1 - 3.4 7.4 0.0 3.4 7.4 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function DUF131 Polysacc_deac_1 PF01522.21 PRP81786.1 - 9.1e-12 45.0 0.0 2.1e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase GFA PF04828.14 PRP81786.1 - 6.1e-09 36.1 0.1 6.1e-09 36.1 0.1 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HECT_2 PF09814.9 PRP81786.1 - 0.036 12.9 0.5 0.056 12.3 0.5 1.3 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding MBOAT PF03062.19 PRP81787.1 - 3.4e-28 99.0 23.2 3.4e-28 99.0 23.2 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Hydrolase PF00702.26 PRP81788.1 - 8.6e-05 22.9 0.0 0.0065 16.8 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PRP81788.1 - 0.00031 20.9 0.0 0.027 14.6 0.0 2.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PAC2 PF09754.9 PRP81788.1 - 0.0064 16.5 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 PAC2 family Hydrolase_like PF13242.6 PRP81788.1 - 0.034 14.2 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 0 HAD-hyrolase-like Isochorismatase PF00857.20 PRP81788.1 - 0.063 13.4 0.0 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Isochorismatase family LpxI_N PF17930.1 PRP81788.1 - 0.15 11.9 0.0 0.46 10.4 0.0 1.9 1 0 0 1 1 1 0 LpxI N-terminal domain FMN_red PF03358.15 PRP81789.1 - 1.9e-10 40.7 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 PRP81789.1 - 8.3e-07 28.9 0.1 1.1e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 PRP81789.1 - 8.8e-05 22.7 0.0 0.0049 17.1 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin DUF3484 PF11983.8 PRP81789.1 - 0.16 13.1 0.3 0.3 12.2 0.3 1.4 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Glyco_hydro_3_C PF01915.22 PRP81790.1 - 4.5e-58 196.6 0.6 1.6e-57 194.8 0.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PRP81790.1 - 5.7e-44 150.8 0.0 9.7e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 PRP81790.1 - 2e-16 59.9 0.0 5.4e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Prismane PF03063.20 PRP81790.1 - 0.035 12.8 0.0 0.058 12.1 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Glyco_hydro_72 PF03198.14 PRP81792.1 - 3.6e-104 348.4 0.6 5.1e-104 347.9 0.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 PRP81792.1 - 3.6e-16 59.6 4.6 8.6e-16 58.4 4.6 1.7 1 0 0 1 1 1 1 X8 domain SPX PF03105.19 PRP81792.1 - 0.0011 19.0 1.4 0.0017 18.4 1.4 1.2 1 0 0 1 1 1 1 SPX domain Glyco_hydro_2_C PF02836.17 PRP81792.1 - 0.0063 15.7 0.0 0.017 14.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 PRP81792.1 - 0.021 14.3 1.5 2.4 7.5 0.0 2.9 3 1 0 3 3 3 0 Cellulase (glycosyl hydrolase family 5) Apt1 PF10351.9 PRP81792.1 - 0.17 10.7 8.1 0.27 10.1 8.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF5427 PF10310.9 PRP81792.1 - 1.3 7.9 6.2 2 7.3 6.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PSP94 PF05825.11 PRP81792.1 - 8.4 7.0 9.5 5.7 7.6 1.2 3.0 3 0 0 3 3 3 0 Beta-microseminoprotein (PSP-94) RIFIN PF02009.16 PRP81792.1 - 8.7 6.1 6.5 18 5.1 6.5 1.5 1 0 0 1 1 1 0 Rifin KAR9 PF08580.10 PRP81792.1 - 9 4.7 14.1 13 4.2 14.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 NmrA PF05368.13 PRP81793.1 - 5.9e-24 84.9 0.7 1.1e-22 80.8 0.6 2.2 2 1 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 PRP81793.1 - 1.8e-08 34.5 0.0 5.8e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 PRP81793.1 - 0.00011 21.7 0.1 0.0002 20.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 PRP81793.1 - 0.00016 21.9 0.0 0.00029 21.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 PRP81793.1 - 0.0054 17.0 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 PRP81793.1 - 0.016 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lipoxygenase PF00305.19 PRP81794.1 - 1.2e-39 136.3 6.5 3e-36 125.1 3.5 2.0 2 0 0 2 2 2 2 Lipoxygenase AMPK1_CBM PF16561.5 PRP81794.1 - 9.6e-06 25.7 0.0 2.8e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Tubulin PF00091.25 PRP81794.1 - 0.086 13.0 0.2 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain AMP-binding PF00501.28 PRP81795.1 - 2.2e-50 171.5 0.0 7.3e-50 169.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 PRP81795.1 - 9e-33 113.5 0.0 6.9e-32 110.6 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein HATPase_c_3 PF13589.6 PRP81795.1 - 8.1e-19 67.8 1.1 2.5e-18 66.2 1.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PP-binding PF00550.25 PRP81795.1 - 1.7e-08 34.7 0.2 3.9e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site SMC_hinge PF06470.13 PRP81795.1 - 3.3e-06 27.4 0.0 1.3e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SET PF00856.28 PRP81795.1 - 4e-06 27.3 0.0 4e-06 27.3 0.0 2.9 3 0 0 3 3 3 1 SET domain HATPase_c PF02518.26 PRP81795.1 - 4.9e-05 23.8 0.7 0.00017 22.0 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Epimerase PF01370.21 PRP81795.1 - 0.0013 18.2 0.0 0.0031 17.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ZZ PF00569.17 PRP81795.1 - 0.0013 18.5 9.7 0.0013 18.5 9.7 2.7 2 0 0 2 2 1 1 Zinc finger, ZZ type ANAPC3 PF12895.7 PRP81795.1 - 0.0066 16.7 1.4 0.014 15.6 0.1 2.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 HATPase_c_2 PF13581.6 PRP81795.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain 3Beta_HSD PF01073.19 PRP81795.1 - 0.03 13.3 0.0 0.087 11.8 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HATPase_c_5 PF14501.6 PRP81795.1 - 0.089 12.7 0.1 0.39 10.6 0.1 2.2 1 0 0 1 1 1 0 GHKL domain RIFIN PF02009.16 PRP81798.1 - 4.8 7.0 7.3 5.4 6.8 7.3 1.1 1 0 0 1 1 1 0 Rifin Pol_alpha_B_N PF08418.10 PRP81798.1 - 6.7 6.6 15.4 8.3 6.3 15.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Smg8_Smg9 PF10220.9 PRP81798.1 - 8.5 4.5 8.4 9.5 4.4 8.4 1.0 1 0 0 1 1 1 0 Smg8_Smg9 HABP4_PAI-RBP1 PF04774.15 PRP81799.1 - 0.15 12.9 1.7 0.27 12.1 1.7 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family SUKH-4 PF14435.6 PRP81800.1 - 0.14 12.2 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 SUKH-4 immunity protein HTH_9 PF08221.11 PRP81801.1 - 0.37 10.9 2.5 0.37 10.9 0.7 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Actin PF00022.19 PRP81802.1 - 1.7e-142 474.8 0.0 5.4e-142 473.2 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 PRP81802.1 - 3.3 7.7 7.9 1 9.3 0.1 2.8 2 1 0 2 2 2 0 Spore germination GerD central core domain Rhabdo_NV PF02484.15 PRP81803.1 - 0.032 14.4 0.2 0.046 13.9 0.2 1.2 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein FAA_hydrolase PF01557.18 PRP81803.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 Fumarylacetoacetate (FAA) hydrolase family Heme_oxygenase PF01126.20 PRP81804.1 - 3.3e-40 138.1 0.7 3.9e-40 137.9 0.7 1.0 1 0 0 1 1 1 1 Heme oxygenase DUF4283 PF14111.6 PRP81804.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) DUF2398 PF09661.10 PRP81804.1 - 0.042 13.1 0.0 0.047 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) bZIP_1 PF00170.21 PRP81806.1 - 1.1e-09 38.3 9.4 2.5e-09 37.1 9.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PRP81806.1 - 9.3e-09 35.7 9.9 1.6e-08 35.0 9.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 PRP81806.1 - 5.9e-06 26.3 9.9 2.7e-05 24.2 9.8 2.2 1 1 0 1 1 1 1 Basic region leucine zipper Cep57_CLD_2 PF14197.6 PRP81806.1 - 0.0012 18.8 2.4 0.0012 18.8 2.4 2.7 3 1 1 4 4 4 1 Centrosome localisation domain of PPC89 APG6_N PF17675.1 PRP81806.1 - 1.1 9.8 8.6 2.6 8.6 8.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region RRM_1 PF00076.22 PRP81807.1 - 1.2e-13 50.6 1.1 1.8e-08 34.1 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.22 PRP81807.1 - 1.6e-13 50.4 0.1 3e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 R3H domain DbpA PF03880.15 PRP81807.1 - 0.0067 16.4 0.0 0.95 9.5 0.0 2.4 2 0 0 2 2 2 1 DbpA RNA binding domain SUZ-C PF12901.7 PRP81807.1 - 0.01 15.8 0.6 0.01 15.8 0.6 2.7 2 0 0 2 2 2 0 SUZ-C motif RRM_occluded PF16842.5 PRP81807.1 - 0.13 12.1 0.0 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif DENN PF02141.21 PRP81808.1 - 4.2e-46 157.3 1.2 5.4e-46 156.9 0.4 1.6 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 PRP81808.1 - 3.4e-13 50.1 0.1 1.8e-12 47.8 0.1 2.4 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 PRP81808.1 - 0.00011 22.1 0.2 0.00024 21.0 0.2 1.5 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 PRP81808.1 - 0.0014 18.6 0.2 0.0028 17.6 0.2 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Cytochrom_C PF00034.21 PRP81808.1 - 0.12 13.5 0.4 0.55 11.4 0.4 2.2 1 0 0 1 1 1 0 Cytochrome c Inhibitor_Mig-6 PF11555.8 PRP81808.1 - 0.12 12.5 8.3 0.8 9.8 8.0 2.5 1 1 0 1 1 1 0 EGFR receptor inhibitor Mig-6 DrsE PF02635.15 PRP81809.1 - 0.12 12.8 0.1 0.49 10.8 0.1 1.9 2 1 0 2 2 2 0 DsrE/DsrF-like family UCR_14kD PF02271.16 PRP81810.1 - 6.6e-22 77.4 2.1 7.6e-22 77.2 2.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Q_salvage PF10343.9 PRP81811.1 - 2.1e-22 80.0 0.0 2.1e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family Nup88 PF10168.9 PRP81811.1 - 1.4e-11 43.0 31.8 4.3e-07 28.1 0.0 3.3 2 1 1 3 3 3 3 Nuclear pore component HSP90 PF00183.18 PRP81812.1 - 5.1e-230 764.8 30.0 7.4e-230 764.2 30.0 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PRP81812.1 - 3.4e-13 50.1 0.1 6.7e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PRP81812.1 - 3.4e-11 43.1 0.1 1.1e-10 41.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M1 PF01433.20 PRP81813.1 - 9.8e-45 152.8 0.1 1.5e-44 152.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 PRP81813.1 - 8.8e-39 132.1 0.1 1.7e-38 131.1 0.1 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 PRP81813.1 - 1.1e-25 90.9 0.1 1.6e-25 90.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain E1_DerP2_DerF2 PF02221.15 PRP81813.1 - 0.13 12.7 0.1 0.24 11.8 0.1 1.3 1 0 0 1 1 1 0 ML domain Peptidase_M61 PF05299.12 PRP81813.1 - 0.67 10.4 2.8 8.9 6.7 2.8 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase MerC PF03203.14 PRP81814.1 - 0.024 15.1 1.4 0.024 15.1 1.4 1.8 1 1 1 2 2 2 0 MerC mercury resistance protein HAD_2 PF13419.6 PRP81816.1 - 1.3e-11 44.9 0.0 1.9e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP81816.1 - 2.8e-10 40.1 0.0 7.3e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 PRP81816.1 - 5.3e-05 23.6 0.0 8.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PRP81816.1 - 0.047 13.8 0.0 0.26 11.4 0.0 2.2 2 2 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Metallophos PF00149.28 PRP81817.1 - 9.6e-13 49.1 1.9 1.8e-12 48.2 1.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PRP81817.1 - 0.0033 17.6 0.1 0.09 13.0 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Troponin PF00992.20 PRP81818.1 - 0.014 15.7 1.8 0.036 14.4 1.8 1.7 1 0 0 1 1 1 0 Troponin Sec20 PF03908.13 PRP81818.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Sec20 Phosphodiest PF01663.22 PRP81820.1 - 1.1e-15 58.1 1.0 7.8e-15 55.3 1.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF325 PF03804.13 PRP81820.1 - 0.00017 21.5 0.1 0.00062 19.7 0.1 1.9 1 0 0 1 1 1 1 Viral proteins of unknown function Sulfatase PF00884.23 PRP81820.1 - 0.045 13.1 0.1 0.6 9.4 0.1 2.1 2 0 0 2 2 2 0 Sulfatase NUC153 PF08159.12 PRP81820.1 - 0.23 11.3 0.7 0.47 10.3 0.7 1.5 1 0 0 1 1 1 0 NUC153 domain DUF4736 PF15883.5 PRP81820.1 - 0.48 10.1 2.3 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) S_4TM PF18159.1 PRP81820.1 - 0.67 9.2 4.3 1.9 7.7 0.6 2.8 2 1 1 3 3 3 0 SMODS-associating 4TM effector domain Prenyltrans PF00432.21 PRP81821.1 - 7.1e-67 220.8 8.8 6.4e-15 54.6 0.1 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 PRP81821.1 - 6.2e-08 32.1 0.0 0.015 14.4 0.0 4.0 1 1 4 5 5 5 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 PRP81821.1 - 0.0002 20.6 0.0 0.0033 16.6 0.0 2.2 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain DUF5492 PF17596.2 PRP81821.1 - 0.087 13.2 0.0 29 5.1 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5492) GntR PF00392.21 PRP81821.1 - 0.18 11.5 0.1 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Copine PF07002.16 PRP81824.1 - 7.1e-60 202.2 0.0 1.1e-59 201.6 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 PRP81824.1 - 1.9e-21 76.3 0.0 3.5e-11 43.3 0.0 2.2 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 PRP81824.1 - 0.00034 20.8 0.0 0.0012 19.0 0.0 1.9 2 0 0 2 2 2 1 vWA found in TerF C terminus Rad52_Rad22 PF04098.15 PRP81826.1 - 2.8e-48 163.7 0.1 3.7e-48 163.3 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein SIMPL PF04402.14 PRP81826.1 - 0.02 15.4 0.0 0.025 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Ribosomal_S5 PF00333.20 PRP81826.1 - 0.069 13.1 1.6 0.14 12.2 1.4 1.7 1 1 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Hydrolase_4 PF12146.8 PRP81827.1 - 0.00048 19.5 0.1 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP81827.1 - 0.00066 19.4 0.0 0.0026 17.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 PRP81827.1 - 0.0068 15.1 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF2920 PF11144.8 PRP81827.1 - 0.058 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) SKA2 PF16740.5 PRP81828.1 - 0.033 14.0 0.8 0.053 13.3 0.8 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 LBP_BPI_CETP_C PF02886.17 PRP81829.1 - 3.3e-32 111.9 0.0 6.4e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain CLN5 PF15014.6 PRP81829.1 - 4.5e-20 72.5 3.3 8.5e-20 71.6 3.3 1.4 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 LBP_BPI_CETP PF01273.25 PRP81829.1 - 1.3e-12 47.6 0.0 3.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain PHA_gran_rgn PF09650.10 PRP81829.1 - 0.13 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) CH PF00307.31 PRP81830.1 - 1.4e-13 51.0 0.2 4.8e-12 46.0 0.0 3.4 2 0 0 2 2 2 1 Calponin homology (CH) domain AAA_lid_3 PF17862.1 PRP81830.1 - 0.017 14.9 0.2 1.8 8.4 0.0 3.2 2 0 0 2 2 2 0 AAA+ lid domain CAMSAP_CH PF11971.8 PRP81830.1 - 0.072 12.9 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain Ribosomal_S14 PF00253.21 PRP81831.1 - 2.6e-13 49.5 1.6 5.2e-13 48.5 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ephrin_rec_like PF07699.13 PRP81831.1 - 1.2 8.9 6.0 6.8 6.5 0.2 2.7 3 0 0 3 3 3 0 Putative ephrin-receptor like IBR PF01485.21 PRP81832.1 - 1.2e-15 57.5 28.4 3.4e-09 36.8 9.2 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 PRP81832.1 - 0.02 14.7 8.3 0.02 14.7 8.3 4.1 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.11 PRP81832.1 - 0.04 13.9 2.3 0.1 12.6 2.3 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain OmpH PF03938.14 PRP81832.1 - 0.1 12.9 0.8 0.17 12.2 0.2 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Wtap PF17098.5 PRP81832.1 - 0.18 11.7 3.2 0.69 9.8 3.2 2.0 1 1 0 1 1 1 0 WTAP/Mum2p family Ferritin_2 PF13668.6 PRP81833.1 - 5e-63 211.3 10.3 5.3e-35 120.6 1.6 2.3 2 0 0 2 2 2 2 Ferritin-like domain Rubrerythrin PF02915.17 PRP81833.1 - 6.2e-08 33.1 0.0 0.23 11.8 0.0 4.0 3 1 1 4 4 4 3 Rubrerythrin FIBP PF05427.11 PRP81835.1 - 6.4e-65 219.8 4.7 8.5e-65 219.4 4.7 1.1 1 0 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) DUF2674 PF10879.8 PRP81835.1 - 0.021 14.3 0.1 0.13 11.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) DUF4795 PF16043.5 PRP81835.1 - 0.47 10.0 5.1 0.59 9.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Tubulin PF00091.25 PRP81836.1 - 1.9e-59 201.2 0.0 2.7e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PRP81836.1 - 1.1e-21 77.3 0.0 4.4e-19 68.9 0.0 2.5 1 1 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 PRP81836.1 - 0.031 13.5 0.0 0.1 11.7 0.0 1.6 1 1 1 2 2 2 0 Tubulin like Misat_Tub_SegII PF10644.9 PRP81836.1 - 0.088 13.1 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain PTEN_C2 PF10409.9 PRP81837.1 - 1.2e-21 76.8 0.6 4.9e-21 74.9 0.6 1.9 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DUF547 PF04784.14 PRP81837.1 - 5.3e-18 65.2 0.0 6.9e-17 61.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF547 DSPc PF00782.20 PRP81837.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP81837.1 - 4.5e-06 26.4 0.0 9.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PRP81837.1 - 0.00075 19.6 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PRP81837.1 - 0.0015 18.6 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family His_Phos_1 PF00300.22 PRP81838.1 - 1.2e-18 67.5 0.0 1.6e-17 63.9 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Peptidase_C80 PF11713.8 PRP81838.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase C80 family Metallophos PF00149.28 PRP81839.1 - 1.8e-38 133.1 0.2 2.2e-38 132.8 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PRP81839.1 - 6.1e-05 23.4 0.6 0.00015 22.2 0.6 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 PRP81839.1 - 0.011 15.9 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PA14 PF07691.12 PRP81840.1 - 8.8e-09 35.3 0.0 1.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 PRP81840.1 - 7.5e-06 25.7 12.0 7.5e-06 25.7 12.0 14.3 16 0 0 16 16 16 5 Dictyostelium (slime mold) repeat Bacteriocin_IIc PF10439.9 PRP81840.1 - 2 8.6 10.9 4.3 7.5 10.9 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF676 PF05057.14 PRP81841.1 - 3.3e-33 115.1 0.0 5.1e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PRP81841.1 - 0.00024 21.0 0.0 0.0031 17.4 0.0 1.9 1 1 0 2 2 2 1 Palmitoyl protein thioesterase LCAT PF02450.15 PRP81841.1 - 0.0033 16.7 0.0 0.0049 16.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 PRP81841.1 - 0.0068 17.0 0.0 0.014 16.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF726 PF05277.12 PRP81841.1 - 0.014 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PGAP1 PF07819.13 PRP81841.1 - 0.033 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 PRP81841.1 - 0.081 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Gelsolin PF00626.22 PRP81842.1 - 3.7e-17 62.0 0.0 3.2e-08 33.4 0.0 3.4 3 0 0 3 3 3 2 Gelsolin repeat C2 PF00168.30 PRP81842.1 - 5.3e-09 36.3 0.1 9e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 C2 domain Laminin_G_3 PF13385.6 PRP81843.1 - 4e-18 66.0 3.3 1.9e-17 63.8 3.3 2.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GMC_oxred_C PF05199.13 PRP81843.1 - 2.1e-15 57.5 0.0 4.8e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 PRP81843.1 - 1.7e-14 53.9 0.0 2.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DUF4982 PF16355.5 PRP81843.1 - 0.00042 20.2 0.0 0.027 14.4 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4982) Carb_bind PF10645.9 PRP81843.1 - 0.058 13.6 16.8 0.03 14.5 12.4 2.3 1 1 1 2 2 2 0 Carbohydrate binding Pex14_N PF04695.13 PRP81843.1 - 3.9 8.1 13.6 5.8 7.5 5.4 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.9 PRP81843.1 - 4.2 6.4 14.9 3 6.9 8.5 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein MORN PF02493.20 PRP81844.1 - 2.2e-14 52.4 35.2 0.00011 21.9 1.1 6.7 7 0 0 7 7 7 4 MORN repeat F-box-like PF12937.7 PRP81844.1 - 1.8e-08 34.1 1.0 4e-08 33.0 1.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP81844.1 - 3e-06 27.0 0.4 6.4e-06 25.9 0.4 1.5 1 0 0 1 1 1 1 F-box domain E1-E2_ATPase PF00122.20 PRP81845.1 - 8.2e-45 152.5 0.7 8.2e-45 152.5 0.7 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PRP81845.1 - 2.2e-37 128.6 11.1 2.4e-37 128.4 4.6 3.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PRP81845.1 - 1.4e-18 68.0 0.0 2e-14 54.4 0.0 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP81845.1 - 3.2e-18 65.6 0.9 3.2e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PRP81845.1 - 3.3e-17 61.9 0.0 7.6e-17 60.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PRP81845.1 - 4.3e-06 26.7 0.4 0.00055 19.8 0.4 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2043 PF09740.9 PRP81845.1 - 0.064 13.9 1.0 0.17 12.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2043) DUF2157 PF09925.9 PRP81845.1 - 0.26 11.1 6.1 0.23 11.2 0.2 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) Phage_holin_3_6 PF07332.11 PRP81845.1 - 1.9 8.5 12.0 2.1 8.4 0.0 3.5 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III LptF_LptG PF03739.14 PRP81845.1 - 2.7 6.8 13.5 6.8 5.4 1.9 4.0 4 0 0 4 4 4 0 Lipopolysaccharide export system permease LptF/LptG DUF983 PF06170.12 PRP81845.1 - 7.5 7.0 9.0 33 5.0 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF1677 PF07911.13 PRP81846.1 - 0.0052 17.1 0.1 0.0052 17.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1677) Trm5_N PF18093.1 PRP81846.1 - 0.038 13.9 0.3 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain Guanylate_cyc PF00211.20 PRP81847.1 - 2.2e-32 112.1 0.1 4.5e-32 111.1 0.1 1.5 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 PRP81848.1 - 1.4e-14 53.0 0.5 7.3e-07 28.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP81848.1 - 6.7e-09 35.2 0.5 0.00091 19.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP81848.1 - 1.1e-08 34.6 0.4 0.00028 20.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP81848.1 - 9.3e-08 32.5 1.3 1.2e-07 32.2 0.4 1.6 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP81848.1 - 1.6e-07 31.9 0.8 5.9e-07 30.0 0.8 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP81848.1 - 1.8e-07 30.7 0.0 0.00018 21.1 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 PRP81848.1 - 7.8e-06 26.3 1.6 0.0036 18.0 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat FKBP_C PF00254.28 PRP81848.1 - 2.3e-05 24.6 0.0 5.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_12 PF13424.6 PRP81848.1 - 4.4e-05 23.7 5.0 0.1 12.9 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 PRP81848.1 - 0.00013 21.7 2.9 0.049 13.5 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP81848.1 - 0.00045 20.4 0.2 0.00086 19.5 0.2 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PRP81848.1 - 0.002 18.2 0.5 0.002 18.2 0.5 1.6 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 PRP81848.1 - 0.014 15.8 0.1 10 6.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PRP81848.1 - 0.019 15.5 0.4 0.2 12.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 PRP81848.1 - 0.034 14.8 2.1 0.035 14.7 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP81848.1 - 0.13 12.3 2.1 12 6.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Nucleoporin_FG PF13634.6 PRP81849.1 - 0.0087 16.9 27.1 0.0087 16.9 27.1 18.4 7 4 8 16 16 16 4 Nucleoporin FG repeat region zf-RanBP PF00641.18 PRP81849.1 - 0.029 13.7 53.1 0.87 9.0 7.4 4.4 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others TPR_8 PF13181.6 PRP81849.1 - 4 7.9 7.3 1.7 9.0 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4485 PF14846.6 PRP81850.1 - 0.013 15.5 0.8 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) DUF1917 PF08939.10 PRP81851.1 - 8.4e-19 68.5 0.4 1.4e-18 67.8 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) FSH1 PF03959.13 PRP81851.1 - 7.9e-13 48.6 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LAG1-DNAbind PF09271.11 PRP81851.1 - 0.15 12.7 0.0 0.41 11.3 0.0 1.7 1 0 0 1 1 1 0 LAG1, DNA binding WD40 PF00400.32 PRP81852.1 - 9.9e-15 54.7 4.7 0.0038 18.0 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP81852.1 - 0.02 15.2 0.0 1.7 9.0 0.0 4.2 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PRP81852.1 - 0.12 11.9 0.0 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 PQQ-like domain DUF1664 PF07889.12 PRP81852.1 - 0.18 11.8 0.8 0.42 10.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) C2 PF00168.30 PRP81853.1 - 0.00018 21.8 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 PRP81854.1 - 1.4e-62 211.4 0.0 4.8e-62 209.7 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81854.1 - 1.1e-42 146.1 0.0 3.7e-42 144.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.9 PRP81854.1 - 0.0038 16.8 0.0 0.0038 16.8 0.0 3.7 6 0 0 6 6 6 1 PhoP regulatory network protein YrbL APH PF01636.23 PRP81854.1 - 0.13 12.1 2.7 0.3 11.0 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family HATPase_c PF02518.26 PRP81857.1 - 2.1e-29 102.3 0.5 4.3e-29 101.3 0.5 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP81857.1 - 3.2e-16 59.5 0.9 1.2e-15 57.7 0.5 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c_3 PF13589.6 PRP81857.1 - 0.00078 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP81857.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP81858.1 - 3.9e-09 36.5 0.1 1.3e-08 34.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PRP81858.1 - 3.8e-07 30.6 0.1 2.2e-06 28.1 0.1 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAM_adeno_trans PF01887.16 PRP81858.1 - 0.051 13.0 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Pkinase PF00069.25 PRP81859.1 - 8.2e-64 215.5 0.2 1.5e-63 214.7 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81859.1 - 7.4e-31 107.4 0.1 1.4e-30 106.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.7 PRP81859.1 - 1.4e-08 34.9 0.1 0.00015 21.9 0.0 3.6 2 1 2 4 4 4 2 PAS domain PAS PF00989.25 PRP81859.1 - 3.6e-06 27.0 0.4 0.12 12.4 0.0 3.5 4 0 0 4 4 4 2 PAS fold RIO1 PF01163.22 PRP81859.1 - 0.00012 21.8 1.3 0.00023 20.8 1.3 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PRP81859.1 - 0.00052 19.4 0.0 0.0065 15.8 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Choline_kinase PF01633.20 PRP81859.1 - 0.0013 18.4 0.1 0.0035 16.9 0.1 1.8 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PRP81859.1 - 0.0059 16.5 0.7 0.06 13.3 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP81859.1 - 0.0073 15.1 1.8 0.0083 14.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP81859.1 - 0.062 12.7 1.6 0.12 11.7 1.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ammonium_transp PF00909.21 PRP81860.1 - 2.1e-64 217.7 20.2 2.9e-64 217.2 20.2 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Ank_5 PF13857.6 PRP81860.1 - 1.2e-21 76.5 0.7 6e-11 42.4 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81860.1 - 5.2e-20 71.8 0.8 4.7e-09 36.7 0.5 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81860.1 - 1.7e-19 69.9 0.7 2.2e-08 34.5 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81860.1 - 1.8e-15 55.5 1.5 0.00045 20.5 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PRP81860.1 - 5.9e-09 36.0 7.8 0.0031 17.9 0.1 5.5 5 0 0 5 5 5 2 Ankyrin repeat GSIII_N PF12437.8 PRP81861.1 - 2.3e-70 235.4 0.0 4.4e-70 234.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 PRP81861.1 - 3.8e-34 117.1 0.2 7.9e-34 116.0 0.2 1.5 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 PRP81861.1 - 7.8e-19 67.9 0.0 1.7e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF2205 PF10224.9 PRP81861.1 - 0.027 14.5 0.6 0.17 11.9 0.0 2.4 2 0 0 2 2 2 0 Short coiled-coil protein HATPase_c PF02518.26 PRP81863.1 - 5.6e-28 97.7 0.8 1.6e-27 96.2 0.8 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP81863.1 - 1.8e-17 63.6 3.7 1.4e-16 60.6 1.5 3.3 2 1 0 2 2 2 1 Response regulator receiver domain Syntaxin-6_N PF09177.11 PRP81863.1 - 6.8e-17 61.8 1.0 6.8e-17 61.8 1.0 4.2 4 1 0 4 4 4 1 Syntaxin 6, N-terminal HisKA PF00512.25 PRP81863.1 - 3.4e-16 59.0 1.1 4.1e-15 55.6 0.0 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain SNARE PF05739.19 PRP81863.1 - 2e-05 24.5 2.4 6.4e-05 22.9 2.4 2.0 1 0 0 1 1 1 1 SNARE domain FleQ PF06490.11 PRP81863.1 - 0.076 13.4 3.4 3.2 8.2 0.1 3.2 3 0 0 3 3 3 0 Flagellar regulatory protein FleQ DUF2929 PF11151.8 PRP81863.1 - 0.11 12.9 1.6 2.6 8.4 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) FliJ PF02050.16 PRP81863.1 - 0.16 12.2 9.2 11 6.2 4.6 3.9 3 1 0 3 3 3 0 Flagellar FliJ protein RIFIN PF02009.16 PRP81863.1 - 0.21 11.5 5.3 0.44 10.4 4.6 1.8 1 1 0 1 1 1 0 Rifin Pkinase PF00069.25 PRP81864.1 - 2.7e-64 217.1 0.0 3.3e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP81864.1 - 3.9e-35 121.4 0.0 5.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP81864.1 - 1.2e-07 31.3 0.0 2.7e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP81864.1 - 5.7e-05 22.1 0.0 0.0001 21.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PRP81864.1 - 0.00053 20.0 0.0 0.055 13.4 0.4 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PRP81864.1 - 0.0032 16.6 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 PRP81864.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP81864.1 - 0.02 14.5 0.1 0.083 12.5 0.0 2.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 PRP81865.1 - 7.6e-14 51.9 7.6 0.54 11.2 0.0 8.7 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP81865.1 - 4.2e-08 33.4 0.0 1.9e-06 28.0 0.0 3.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 PRP81865.1 - 4.9e-05 23.1 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 HELP motif eIF2A PF08662.11 PRP81865.1 - 0.0019 18.1 0.0 0.038 13.9 0.0 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A EF-hand_7 PF13499.6 PRP81865.1 - 0.01 16.2 0.3 0.16 12.4 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain pair Podoplanin PF05808.11 PRP81866.1 - 4 7.5 10.2 0.18 11.9 3.2 2.3 2 0 0 2 2 2 0 Podoplanin C2 PF00168.30 PRP81867.1 - 5.6e-11 42.7 0.0 1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain LRR_8 PF13855.6 PRP81868.1 - 2.4e-66 219.4 88.9 3.9e-07 29.7 2.9 18.0 9 5 9 18 18 18 17 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP81868.1 - 4.3e-61 206.4 0.8 4.6e-60 203.1 0.2 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP81868.1 - 3.4e-48 160.8 85.2 1.1e-05 25.7 0.0 20.2 8 4 17 27 27 27 19 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP81868.1 - 1.5e-43 149.1 0.1 1.3e-42 146.0 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain LRR_1 PF00560.33 PRP81868.1 - 3.5e-18 63.3 76.0 0.51 11.1 0.3 26.8 27 5 0 27 27 26 5 Leucine Rich Repeat LRR_6 PF13516.6 PRP81868.1 - 4e-12 45.1 70.5 1.6 9.0 0.0 23.1 26 0 0 26 26 26 7 Leucine Rich repeat LRR_5 PF13306.6 PRP81868.1 - 1.9e-05 24.6 1.9 0.00082 19.3 0.3 3.4 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Pkinase_fungal PF17667.1 PRP81868.1 - 0.003 16.4 0.0 0.0051 15.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP81868.1 - 0.0052 15.8 0.7 0.029 13.3 0.7 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP81868.1 - 0.044 13.1 0.1 0.099 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP81868.1 - 0.16 11.2 0.0 0.4 10.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like EMP70 PF02990.16 PRP81869.1 - 1.7e-140 469.1 10.2 1.7e-140 469.1 10.2 1.8 2 0 0 2 2 2 1 Endomembrane protein 70 Wzz PF02706.15 PRP81869.1 - 0.14 12.5 0.9 2.4 8.5 0.0 2.9 2 0 0 2 2 2 0 Chain length determinant protein NHase_beta PF02211.15 PRP81870.1 - 0.037 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Snf7 PF03357.21 PRP81870.1 - 0.13 11.8 1.3 0.52 9.9 0.2 2.1 2 0 0 2 2 2 0 Snf7 Hpt PF01627.23 PRP81870.1 - 0.16 12.2 1.6 16 5.8 0.3 2.4 2 0 0 2 2 2 0 Hpt domain RGS PF00615.19 PRP81871.1 - 2.7e-18 66.3 0.2 4.4e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain INTS2 PF14750.6 PRP81873.1 - 1.1e-89 301.4 20.7 1.3e-64 218.4 9.0 2.9 2 1 0 2 2 2 2 Integrator complex subunit 2 Xpo1 PF08389.12 PRP81873.1 - 0.85 9.7 6.6 0.86 9.6 0.4 3.4 3 0 0 3 3 3 0 Exportin 1-like protein BCNT PF07572.12 PRP81874.1 - 2.1e-23 82.2 2.8 3.6e-23 81.4 2.8 1.4 1 0 0 1 1 1 1 Bucentaur or craniofacial development WW PF00397.26 PRP81875.1 - 2.1e-13 50.1 0.3 3.8e-13 49.3 0.3 1.5 1 0 0 1 1 1 1 WW domain TTL PF03133.15 PRP81878.1 - 2.3e-46 158.3 0.4 5e-46 157.2 0.4 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family U-box PF04564.15 PRP81878.1 - 3.3e-12 46.4 0.0 8.6e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 U-box domain SAM_1 PF00536.30 PRP81878.1 - 4.1e-08 33.6 0.5 1.2e-05 25.7 0.1 2.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP81878.1 - 7.3e-06 26.0 1.0 0.00013 22.0 0.1 3.0 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) LRR_6 PF13516.6 PRP81878.1 - 0.00027 20.7 2.7 0.048 13.7 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich repeat SHE3 PF17078.5 PRP81878.1 - 0.00097 18.9 8.4 0.003 17.3 8.4 1.8 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 zf-NOSIP PF15906.5 PRP81878.1 - 0.024 14.8 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein SAM_PNT PF02198.16 PRP81878.1 - 0.037 14.0 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Cluap1 PF10234.9 PRP81878.1 - 4 6.8 11.9 3.5 6.9 2.8 2.4 1 1 1 2 2 2 0 Clusterin-associated protein-1 SNARE_assoc PF09335.11 PRP81879.1 - 1.2e-27 96.7 3.0 1.2e-27 96.7 3.0 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein TPPK_C PF12555.8 PRP81879.1 - 0.46 10.6 3.1 9.3 6.4 0.0 3.2 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal TNV_CP PF03898.13 PRP81880.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein FKBP_C PF00254.28 PRP81881.1 - 5e-16 58.8 0.0 2.3e-15 56.7 0.0 2.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ZapB PF06005.12 PRP81881.1 - 0.0033 17.8 6.4 0.0033 17.8 6.4 9.1 5 4 0 6 6 6 1 Cell division protein ZapB CH PF00307.31 PRP81882.1 - 1.9e-57 192.2 0.0 6.1e-20 71.4 0.1 5.4 5 0 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP81882.1 - 2.3e-09 36.9 0.0 0.0012 18.7 0.0 4.5 4 0 0 4 4 4 3 CAMSAP CH domain NDK PF00334.19 PRP81883.1 - 2.6e-50 169.9 0.0 9e-27 93.7 0.0 2.7 2 1 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 PRP81883.1 - 3.3e-05 23.7 0.6 0.00032 20.5 0.5 2.4 2 1 0 2 2 2 1 DUF1126 PH-like domain HA PF03457.14 PRP81884.1 - 4.7e-24 84.5 4.0 4.7e-16 58.9 1.1 2.3 2 0 0 2 2 2 2 Helicase associated domain LAT PF15234.6 PRP81884.1 - 0.021 14.5 0.1 7.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells Flavi_M PF01004.19 PRP81884.1 - 0.033 13.9 0.1 11 5.9 0.0 2.5 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M Auxin_canalis PF05703.11 PRP81884.1 - 0.077 12.9 0.8 0.24 11.3 0.2 2.0 2 0 0 2 2 2 0 Auxin canalisation DUF938 PF06080.12 PRP81885.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Glutaminase PF04960.15 PRP81886.1 - 8.8e-105 350.0 0.0 1.2e-104 349.5 0.0 1.2 1 0 0 1 1 1 1 Glutaminase Ank_5 PF13857.6 PRP81886.1 - 1.8e-09 37.6 0.0 4.4e-06 26.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP81886.1 - 9.3e-07 29.3 0.0 2.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP81886.1 - 1.4e-06 28.7 0.3 0.00053 20.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP81886.1 - 0.078 13.5 0.1 12 6.6 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 PRP81886.1 - 0.15 12.7 0.0 1.6 9.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Gelsolin PF00626.22 PRP81887.1 - 3.4e-41 139.0 0.5 4.1e-14 52.2 0.0 3.1 3 0 0 3 3 3 3 Gelsolin repeat CDC73_C PF05179.14 PRP81888.1 - 1e-44 152.0 4.3 2.3e-44 150.8 4.3 1.6 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 PRP81888.1 - 2.9e-19 69.5 6.1 2.1e-12 47.0 0.0 2.8 2 1 1 3 3 3 2 Paf1 complex subunit CDC73 N-terminal ARS2 PF04959.13 PRP81888.1 - 0.039 14.3 0.2 2.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Arsenite-resistance protein 2 p450 PF00067.22 PRP81889.1 - 2.1e-76 257.5 0.2 2.4e-76 257.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cytochrom_B561 PF03188.16 PRP81890.1 - 3.8e-11 43.3 5.0 3.8e-11 43.3 5.0 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 PRP81890.1 - 0.018 15.2 12.2 0.28 11.3 2.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) Peptidase_C53 PF05550.11 PRP81890.1 - 0.027 14.1 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 DUF998 PF06197.13 PRP81890.1 - 0.92 9.1 22.9 0.037 13.6 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF2852 PF11014.8 PRP81890.1 - 1.1 9.5 2.7 22 5.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) LapA_dom PF06305.11 PRP81890.1 - 1.7 8.5 5.7 0.56 10.1 0.3 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2427 PF10348.9 PRP81890.1 - 2.3 8.1 12.6 1.6 8.5 9.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF3325 PF11804.8 PRP81890.1 - 4.5 7.5 15.6 4.6 7.5 2.6 3.8 3 1 2 5 5 5 0 Protein of unknown function (DUF3325) SUR7 PF06687.12 PRP81890.1 - 5.5 6.5 7.7 16 5.0 4.4 2.3 1 1 1 2 2 2 0 SUR7/PalI family DUF2985 PF11204.8 PRP81890.1 - 7.1 6.9 8.4 1.5 9.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2985) MIG-14_Wnt-bd PF06664.12 PRP81891.1 - 0.058 12.6 0.0 0.067 12.4 0.0 1.0 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Ank_4 PF13637.6 PRP81892.1 - 0.0096 16.5 1.1 3e+02 2.1 0.0 6.0 6 1 2 8 8 8 0 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP81892.1 - 0.055 13.4 0.2 0.12 12.3 0.2 1.6 1 0 0 1 1 1 0 F-box-like Dicer_N PF17895.1 PRP81893.1 - 0.07 13.0 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain Cytochrom_B561 PF03188.16 PRP81896.1 - 1.2e-11 44.9 6.4 1.2e-11 44.9 6.4 2.0 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 UbiA PF01040.18 PRP81896.1 - 3.5e-06 26.5 11.9 5.4e-06 25.9 11.9 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF998 PF06197.13 PRP81896.1 - 0.014 15.0 5.7 0.014 15.0 5.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF4079 PF13301.6 PRP81896.1 - 0.031 14.4 16.0 0.19 11.9 2.6 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF4079) DUF2663 PF10864.8 PRP81896.1 - 0.15 12.5 2.2 6.5 7.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) LYRIC PF15686.5 PRP81896.1 - 0.18 11.4 1.4 0.26 10.8 1.4 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF4131 PF13567.6 PRP81896.1 - 1.2 8.8 11.4 1 9.0 1.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF2852 PF11014.8 PRP81896.1 - 1.7 8.8 3.9 28 4.9 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) p450 PF00067.22 PRP81897.1 - 2.3e-76 257.4 0.2 2.8e-76 257.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAM91_C PF14648.6 PRP81899.1 - 7.4e-120 400.7 0.0 8.3e-104 347.8 0.0 2.2 1 1 1 2 2 2 2 FAM91 C-terminus FAM91_N PF14647.6 PRP81899.1 - 1.6e-100 336.4 6.1 1.8e-99 333.0 6.1 2.1 1 1 0 1 1 1 1 FAM91 N-terminus DUF4407 PF14362.6 PRP81899.1 - 0.055 12.8 1.7 0.12 11.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1771 PF08590.10 PRP81899.1 - 0.65 10.4 7.3 0.44 11.0 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) MOSC PF03473.17 PRP81901.1 - 1.5e-32 112.3 0.0 3e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 PRP81901.1 - 7.1e-32 110.8 0.0 9.4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 PRP81901.1 - 1.3e-24 86.4 0.0 2.1e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain UCH PF00443.29 PRP81902.1 - 1.7e-45 155.5 0.0 2.6e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 PRP81902.1 - 2e-21 75.5 0.2 4.7e-12 45.5 0.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 PRP81902.1 - 3.5e-19 68.3 0.1 1.1e-18 66.7 0.1 1.9 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 PRP81902.1 - 1.2e-15 57.6 0.0 3.6e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 PRP81902.1 - 4.4e-15 56.1 0.5 1.3e-13 51.3 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_3 PF09288.10 PRP81902.1 - 0.031 14.1 0.0 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Aa_trans PF01490.18 PRP81903.1 - 1.4e-48 165.6 26.7 1.7e-48 165.4 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2976 PF11190.8 PRP81903.1 - 0.1 12.4 4.3 7.6 6.4 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Sigma_reg_N PF13800.6 PRP81903.1 - 0.25 11.7 1.9 4.9 7.5 0.0 3.4 3 0 0 3 3 3 0 Sigma factor regulator N-terminal COX4_pro_2 PF07835.12 PRP81903.1 - 0.47 10.6 5.1 0.32 11.1 0.6 2.7 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV SurA_N_3 PF13624.6 PRP81903.1 - 1.9 8.3 3.9 0.5 10.1 0.2 1.9 2 0 0 2 2 2 0 SurA N-terminal domain Pkinase_Tyr PF07714.17 PRP81904.1 - 5.3e-62 209.4 0.0 9.9e-62 208.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81904.1 - 1.5e-51 175.3 0.0 4.1e-51 173.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Beta_helix PF13229.6 PRP81904.1 - 2.9e-09 37.0 98.3 0.0021 17.9 17.9 7.2 2 1 5 7 7 7 6 Right handed beta helix region Kdo PF06293.14 PRP81904.1 - 0.0026 17.2 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP81904.1 - 0.003 16.9 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP81904.1 - 0.011 14.5 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase EphA2_TM PF14575.6 PRP81904.1 - 0.039 14.8 0.6 0.3 12.0 0.1 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_S9_N PF02897.15 PRP81906.1 - 1.9e-56 191.7 7.6 2.6e-56 191.2 7.6 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PRP81906.1 - 2.6e-50 170.8 0.9 7.5e-50 169.3 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PRP81906.1 - 0.0023 17.2 0.1 0.0045 16.3 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 zf-ZPR1 PF03367.13 PRP81906.1 - 0.078 12.8 0.1 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain GIT_CC PF16559.5 PRP81907.1 - 0.00071 19.4 4.9 0.0012 18.7 4.9 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor KxDL PF10241.9 PRP81907.1 - 0.0042 17.3 6.2 0.0065 16.7 6.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF737 PF05300.11 PRP81907.1 - 0.0053 17.1 3.9 0.0082 16.5 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) Lebercilin PF15619.6 PRP81907.1 - 0.012 15.3 3.5 0.016 14.9 3.5 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease RskA PF10099.9 PRP81907.1 - 0.015 15.6 0.0 0.018 15.3 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA HemX PF04375.14 PRP81907.1 - 0.041 13.2 3.9 0.052 12.8 3.9 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Gastrin PF00918.17 PRP81907.1 - 0.047 14.6 0.7 0.074 14.0 0.7 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family ADIP PF11559.8 PRP81907.1 - 0.063 13.4 6.2 0.1 12.7 6.2 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 PRP81907.1 - 0.063 13.7 1.8 0.063 13.7 1.8 2.3 1 1 1 2 2 2 0 Cell division protein ZapB TMF_DNA_bd PF12329.8 PRP81907.1 - 0.15 12.0 7.0 0.25 11.4 7.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMCO5 PF14992.6 PRP81907.1 - 0.19 11.3 5.4 0.12 11.9 3.8 1.5 1 1 0 1 1 1 0 TMCO5 family DivIC PF04977.15 PRP81907.1 - 0.38 10.6 7.2 0.18 11.6 5.0 1.7 2 0 0 2 2 2 0 Septum formation initiator Mto2_bdg PF12808.7 PRP81907.1 - 1.2 9.4 5.5 9.8 6.6 0.6 2.4 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Csm1_N PF18504.1 PRP81907.1 - 3.3 8.1 8.1 6.7 7.1 2.4 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain MORN PF02493.20 PRP81908.1 - 1e-59 195.0 90.9 1.1e-07 31.3 2.2 13.1 13 0 0 13 13 13 12 MORN repeat DUF3048_C PF17479.2 PRP81908.1 - 0.0057 17.0 29.0 0.6 10.5 1.2 6.7 1 1 5 6 6 6 3 Protein of unknown function (DUF3048) C-terminal domain DnaJ PF00226.31 PRP81909.1 - 3.4e-09 36.7 0.0 2.9e-08 33.7 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain TraT PF05818.12 PRP81910.1 - 0.087 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Motilin_ghrelin PF04644.12 PRP81910.1 - 0.32 10.8 1.7 0.59 10.0 1.7 1.4 1 0 0 1 1 1 0 Motilin/ghrelin Pkinase_Tyr PF07714.17 PRP81912.1 - 5.6e-66 222.5 0.0 2e-65 220.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81912.1 - 2.2e-48 165.0 0.0 3.2e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP81912.1 - 0.0034 16.8 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP81912.1 - 0.0082 15.0 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase GvpL_GvpF PF06386.11 PRP81912.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Kinase-like PF14531.6 PRP81912.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Gly-zipper_YMGG PF13441.6 PRP81912.1 - 0.02 14.6 1.5 0.078 12.7 1.5 2.1 1 0 0 1 1 1 0 YMGG-like Gly-zipper Haspin_kinase PF12330.8 PRP81912.1 - 0.024 13.6 0.1 0.074 12.0 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 PRP81912.1 - 0.19 11.6 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PRP81913.1 - 1.2e-67 227.9 0.0 1.7e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP81913.1 - 1.8e-48 165.2 0.0 2.5e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SKG6 PF08693.10 PRP81913.1 - 6.2e-06 25.5 1.1 1.4e-05 24.4 1.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 PRP81913.1 - 0.001 17.9 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP81913.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Chlam_PMP PF02415.17 PRP81913.1 - 0.01 16.2 66.1 1.9 9.2 0.0 15.6 15 1 0 15 15 15 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NicO PF03824.16 PRP81913.1 - 0.028 13.8 0.2 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF5305 PF17231.2 PRP81913.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Kinase-like PF14531.6 PRP81913.1 - 0.11 11.8 0.0 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like UQ_con PF00179.26 PRP81914.1 - 4.7e-23 81.4 0.0 1.7e-22 79.6 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SPRY PF00622.28 PRP81914.1 - 6.9e-15 55.2 0.2 1.6e-14 54.0 0.2 1.7 1 0 0 1 1 1 1 SPRY domain UEV PF05743.13 PRP81914.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 UEV domain Xpo1 PF08389.12 PRP81914.1 - 0.03 14.4 5.7 0.25 11.4 0.1 4.3 5 0 0 5 5 5 0 Exportin 1-like protein RWD PF05773.22 PRP81914.1 - 0.076 13.3 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 RWD domain DUF3467 PF11950.8 PRP81915.1 - 0.026 14.7 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3467) Pept_tRNA_hydro PF01195.19 PRP81915.1 - 0.036 14.0 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase Aminotran_5 PF00266.19 PRP81916.1 - 1.6e-93 313.7 0.0 1.9e-93 313.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PRP81916.1 - 4.1e-08 32.8 0.0 6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 PRP81916.1 - 6.7e-06 25.6 0.1 1.2e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 PRP81916.1 - 0.013 14.2 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain B12-binding PF02310.19 PRP81916.1 - 0.044 13.8 0.0 4.8 7.2 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain DUF600 PF04634.12 PRP81916.1 - 0.076 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF600 TspO_MBR PF03073.15 PRP81919.1 - 6e-42 142.9 14.4 6.9e-42 142.7 14.4 1.0 1 0 0 1 1 1 1 TspO/MBR family WASH_WAHD PF11945.8 PRP81920.1 - 1.3e-48 166.1 0.0 1.8e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 PRP81920.1 - 0.0018 18.0 0.6 0.0039 17.0 0.6 1.5 1 0 0 1 1 1 1 WH2 motif DUF4903 PF16246.5 PRP81921.1 - 0.075 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) WD40 PF00400.32 PRP81922.1 - 0.0017 19.1 3.1 37 5.4 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.6 PRP81922.1 - 0.13 12.8 0.6 14 6.3 0.1 3.5 3 1 0 3 3 3 0 PQQ-like domain LRR_8 PF13855.6 PRP81923.1 - 4.7e-09 35.9 12.5 2.6e-06 27.1 1.3 5.5 4 2 2 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PRP81923.1 - 2.2e-07 31.0 31.7 0.01 16.2 3.6 8.3 6 1 0 7 7 7 4 Leucine Rich repeats (2 copies) G8 PF10162.9 PRP81924.1 - 4.8e-20 71.9 0.1 2.2e-19 69.7 0.1 2.2 1 0 0 1 1 1 1 G8 domain DUF2190 PF09956.9 PRP81924.1 - 0.54 10.8 4.0 3.7 8.1 2.2 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2190) Carboxyl_trans PF01039.22 PRP81925.1 - 1.7e-149 498.7 0.2 2.2e-149 498.3 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 PRP81925.1 - 0.034 13.7 0.1 0.71 9.3 0.0 2.1 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) TPR_19 PF14559.6 PRP81926.1 - 8.9e-10 38.9 0.0 0.007 16.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP81926.1 - 3e-09 36.3 0.0 0.0058 16.6 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP81926.1 - 7.7e-07 28.7 0.0 0.025 14.4 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP81926.1 - 1e-06 28.7 0.2 0.063 13.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP81926.1 - 2.7e-06 27.2 0.0 0.023 14.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP81926.1 - 5.3e-06 26.6 0.6 0.043 14.1 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP81926.1 - 2.3e-05 24.5 0.0 0.061 13.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP81926.1 - 6e-05 23.5 0.0 6.3 7.9 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP81926.1 - 0.0029 17.0 0.1 0.0049 16.3 0.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region DUF4919 PF16266.5 PRP81926.1 - 0.0045 17.0 0.1 0.016 15.1 0.1 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4919) TPR_16 PF13432.6 PRP81926.1 - 0.0059 17.2 0.0 7 7.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP81926.1 - 0.0072 16.3 0.0 0.59 10.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP81926.1 - 0.013 16.1 0.1 34 5.4 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP81926.1 - 0.021 14.5 0.0 7.3 6.4 0.0 2.8 2 0 0 2 2 2 0 TPR repeat DUF3808 PF10300.9 PRP81926.1 - 0.042 12.6 0.1 0.063 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) RPN7 PF10602.9 PRP81926.1 - 0.057 13.1 0.1 0.44 10.2 0.2 2.1 2 0 0 2 2 2 0 26S proteasome subunit RPN7 PknG_TPR PF16918.5 PRP81926.1 - 0.12 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat 3D PF06725.11 PRP81927.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 3D domain Rgp1 PF08737.10 PRP81928.1 - 1.8e-29 103.2 5.0 5.9e-21 75.1 0.8 2.3 1 1 0 2 2 2 2 Rgp1 Arrestin_N PF00339.29 PRP81928.1 - 0.034 14.2 0.1 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain ABC_trans_N PF14510.6 PRP81929.1 - 0.0047 17.5 0.1 0.013 16.0 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal DDE_Tnp_4 PF13359.6 PRP81930.1 - 9e-28 96.9 0.0 1.5e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP81930.1 - 1.2e-09 38.1 0.5 6e-09 35.9 0.5 2.0 1 1 0 1 1 1 1 Transposase DDE domain Plant_tran PF04827.14 PRP81930.1 - 0.00013 21.7 0.0 0.00026 20.6 0.0 1.7 1 1 0 1 1 1 1 Plant transposon protein DUF2405 PF10293.9 PRP81930.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Retrotrans_gag PF03732.17 PRP81931.1 - 0.0024 18.1 3.4 0.0042 17.3 0.0 2.8 3 0 0 3 3 3 1 Retrotransposon gag protein Ribosomal_L11_N PF03946.14 PRP81931.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Asp_protease_2 PF13650.6 PRP81931.1 - 0.085 13.5 0.1 0.19 12.4 0.1 1.5 1 0 0 1 1 1 0 Aspartyl protease ZapB PF06005.12 PRP81931.1 - 0.32 11.5 6.8 0.78 10.2 0.0 3.5 4 0 0 4 4 4 0 Cell division protein ZapB ubiquitin PF00240.23 PRP81932.1 - 2.2e-07 30.5 0.0 4.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 PRP81932.1 - 0.01 15.9 0.0 0.03 14.4 0.0 1.7 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PRP81932.1 - 0.025 15.1 0.0 0.043 14.4 0.0 1.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 PRP81932.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BAR PF03114.18 PRP81933.1 - 7.5e-21 74.9 10.1 1.2e-20 74.2 10.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 PRP81933.1 - 5.8e-10 38.6 0.1 9.3e-10 38.0 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP81933.1 - 2.6e-09 36.8 0.2 4.2e-09 36.1 0.2 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP81933.1 - 1.6e-08 34.1 0.0 2.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Arfaptin PF06456.13 PRP81933.1 - 0.00065 19.3 5.5 0.00095 18.8 5.5 1.3 1 0 0 1 1 1 1 Arfaptin-like domain CREPT PF16566.5 PRP81933.1 - 1.8 8.8 6.9 3.7 7.7 0.6 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Vps16_N PF04841.13 PRP81934.1 - 1.4e-76 257.9 0.0 2.1e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 PRP81934.1 - 2.4e-76 256.8 1.3 3.4e-76 256.3 1.3 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region adh_short PF00106.25 PRP81935.1 - 2.8e-38 131.4 0.6 3.5e-38 131.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP81935.1 - 9e-22 77.8 0.3 1.2e-21 77.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP81935.1 - 1.3e-08 35.0 0.7 3.6e-08 33.5 0.7 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 PRP81935.1 - 0.024 14.9 0.2 0.061 13.6 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pkinase_Tyr PF07714.17 PRP81936.1 - 3.5e-51 174.0 0.0 6.9e-51 173.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CAP59_mtransfer PF11735.8 PRP81936.1 - 5.4e-50 170.3 0.0 9.1e-50 169.6 0.0 1.4 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Pkinase PF00069.25 PRP81936.1 - 1.6e-39 135.9 0.0 3.3e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP81936.1 - 2e-20 72.5 57.8 0.0031 17.9 0.1 10.6 5 3 7 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP81936.1 - 1.4e-18 66.4 64.8 0.00028 20.6 5.0 9.2 2 2 13 15 15 15 13 Leucine rich repeat Pentapeptide_4 PF13599.6 PRP81936.1 - 0.032 14.4 2.2 1.8 8.8 0.9 3.9 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) Kdo PF06293.14 PRP81936.1 - 0.041 13.2 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EphA2_TM PF14575.6 PRP81936.1 - 0.15 12.9 0.2 0.36 11.7 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_9 PF14580.6 PRP81936.1 - 0.71 9.3 23.5 0.18 11.3 0.8 5.7 2 1 4 7 7 7 0 Leucine-rich repeat CAP59_mtransfer PF11735.8 PRP81937.1 - 2.7e-51 174.6 0.0 3.5e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Pyrid_oxidase_2 PF13883.6 PRP81938.1 - 1.7e-07 31.4 0.0 2.4e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 PRP81938.1 - 0.0012 19.5 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Glyco_hydro_20 PF00728.22 PRP81939.1 - 9.9e-75 252.1 6.7 9.9e-75 252.1 6.7 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Metallophos PF00149.28 PRP81939.1 - 4.7e-22 79.5 2.7 4.8e-22 79.5 0.1 2.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PRP81939.1 - 5.1e-20 71.8 0.9 5.1e-20 71.8 0.9 2.4 2 0 0 2 2 1 1 Purple acid Phosphatase, N-terminal domain Glycohydro_20b2 PF14845.6 PRP81939.1 - 2.9e-14 53.9 3.3 5.7e-14 52.9 0.5 2.9 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Metallophos_C PF14008.6 PRP81939.1 - 5.4e-14 52.8 0.2 3.5e-13 50.2 0.0 2.6 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Glyco_hydro_20b PF02838.15 PRP81939.1 - 3.1e-08 34.4 0.0 1.4e-07 32.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 BatA PF07584.11 PRP81939.1 - 0.0063 16.9 0.2 0.041 14.3 0.1 2.5 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal PhoD PF09423.10 PRP81939.1 - 0.021 13.9 0.2 0.071 12.1 0.0 1.8 2 0 0 2 2 2 0 PhoD-like phosphatase Metallophos_2 PF12850.7 PRP81939.1 - 0.032 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain NCD3G PF07562.14 PRP81939.1 - 0.037 14.0 0.3 0.037 14.0 0.3 2.9 3 0 0 3 3 1 0 Nine Cysteines Domain of family 3 GPCR DUF4969 PF16339.5 PRP81939.1 - 0.077 13.4 0.0 0.36 11.2 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) SapB_1 PF05184.15 PRP81939.1 - 3.9 7.6 7.3 0.41 10.7 1.7 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 Rhomboid PF01694.22 PRP81940.1 - 7.5e-29 100.7 11.1 1.5e-28 99.7 11.1 1.5 1 0 0 1 1 1 1 Rhomboid family DUF3431 PF11913.8 PRP81940.1 - 1.7e-27 96.6 2.2 3.5e-27 95.6 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) G-patch PF01585.23 PRP81940.1 - 3.1e-10 39.8 0.3 8.8e-10 38.3 0.3 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PRP81940.1 - 0.001 19.1 0.5 0.001 19.1 0.5 3.2 3 1 0 3 3 2 1 G-patch domain YL1 PF05764.13 PRP81940.1 - 0.15 12.2 32.8 0.23 11.5 32.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC27 PF09507.10 PRP81940.1 - 0.42 9.9 37.4 0.64 9.3 37.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF262 PF03235.14 PRP81940.1 - 0.97 9.6 11.9 2.2 8.4 11.9 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF262 Neur_chan_memb PF02932.16 PRP81940.1 - 1 9.3 6.8 1.9 8.5 6.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 PRP81940.1 - 3.4 7.4 25.4 6.4 6.5 25.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mitofilin PF09731.9 PRP81940.1 - 5.5 5.7 28.3 7.7 5.2 28.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AAA_11 PF13086.6 PRP81940.1 - 7.9 6.2 17.9 14 5.4 17.9 1.4 1 0 0 1 1 1 0 AAA domain HARE-HTH PF05066.13 PRP81941.1 - 1.3e-10 41.5 0.0 3.7e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain betaPIX_CC PF16523.5 PRP81941.1 - 0.0023 17.7 0.4 0.0068 16.2 0.4 1.8 1 0 0 1 1 1 1 betaPIX coiled coil AMPK1_CBM PF16561.5 PRP81942.1 - 7.9e-38 128.6 9.7 8.7e-13 48.3 0.4 3.7 3 0 0 3 3 3 3 Glycogen recognition site of AMP-activated protein kinase BCS1_N PF08740.11 PRP81942.1 - 5.1e-35 121.1 0.0 5.1e-35 121.1 0.0 3.6 3 1 0 3 3 2 1 BCS1 N terminal AAA PF00004.29 PRP81942.1 - 2.9e-19 69.8 0.7 1.9e-18 67.2 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Pur_ac_phosph_N PF16656.5 PRP81942.1 - 4.3e-10 40.0 8.0 0.0051 17.4 0.2 4.5 3 0 0 3 3 3 3 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 PRP81942.1 - 0.0011 19.5 3.1 8.2 7.0 0.0 5.5 4 1 1 5 5 5 1 PhoD-like phosphatase, N-terminal domain AAA_33 PF13671.6 PRP81942.1 - 0.0018 18.4 0.4 0.024 14.8 0.0 3.2 2 0 0 2 2 2 1 AAA domain fn3 PF00041.21 PRP81942.1 - 0.022 15.1 0.0 9 6.7 0.0 3.4 3 0 0 3 3 3 0 Fibronectin type III domain ABC_tran PF00005.27 PRP81942.1 - 0.036 14.6 0.0 0.036 14.6 0.0 5.0 5 2 1 6 6 4 0 ABC transporter AAA_16 PF13191.6 PRP81942.1 - 0.037 14.4 0.1 0.037 14.4 0.1 4.4 4 2 0 4 4 3 0 AAA ATPase domain AAA_5 PF07728.14 PRP81942.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP81942.1 - 0.077 13.3 0.2 0.9 9.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PRP81942.1 - 1.8 8.3 0.0 1.8 8.3 0.0 8.9 4 2 1 5 5 2 0 AAA domain PseudoU_synth_2 PF00849.22 PRP81943.1 - 2e-14 54.0 0.1 1.1e-13 51.6 0.0 1.9 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF2457 PF10446.9 PRP81945.1 - 1.9 7.5 16.1 2.3 7.2 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RhoGAP PF00620.27 PRP81946.1 - 6.3e-28 97.5 0.0 5e-27 94.6 0.0 2.0 1 1 0 1 1 1 1 RhoGAP domain LSM PF01423.22 PRP81947.1 - 3.1e-19 68.4 3.2 4.6e-19 67.9 3.2 1.3 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 PRP81947.1 - 0.015 15.1 0.5 0.031 14.2 0.5 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain SM-ATX PF14438.6 PRP81947.1 - 0.037 14.2 0.3 0.046 13.9 0.3 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 PRP81947.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) bZIP_1 PF00170.21 PRP81948.1 - 9.2e-06 25.7 11.9 0.0065 16.5 2.7 3.2 1 1 2 3 3 3 2 bZIP transcription factor DivIC PF04977.15 PRP81948.1 - 1.9e-05 24.4 6.7 0.059 13.1 3.2 2.9 1 1 1 2 2 2 2 Septum formation initiator DUF3450 PF11932.8 PRP81948.1 - 5.5e-05 22.6 4.8 0.0036 16.6 0.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) ZapB PF06005.12 PRP81948.1 - 7.4e-05 23.1 8.9 0.00011 22.6 7.3 2.1 1 1 1 2 2 2 1 Cell division protein ZapB BLOC1_2 PF10046.9 PRP81948.1 - 0.00013 22.2 6.5 0.00086 19.6 6.4 1.9 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 PRP81948.1 - 0.00022 20.2 4.0 0.00026 20.0 4.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein KASH_CCD PF14662.6 PRP81948.1 - 0.00029 20.7 8.4 0.011 15.6 4.7 1.8 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH MAD PF05557.13 PRP81948.1 - 0.00045 18.7 4.2 0.00055 18.5 4.2 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein HALZ PF02183.18 PRP81948.1 - 0.00055 20.1 7.0 0.0043 17.2 0.2 2.8 1 1 3 4 4 4 1 Homeobox associated leucine zipper APG6_N PF17675.1 PRP81948.1 - 0.00071 20.1 2.0 0.00082 19.9 2.0 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF4686 PF15742.5 PRP81948.1 - 0.00075 18.7 4.8 0.00093 18.4 4.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) UPF0449 PF15136.6 PRP81948.1 - 0.00077 19.9 6.0 0.018 15.5 2.8 2.5 1 1 1 2 2 2 1 Uncharacterised protein family UPF0449 MAP65_ASE1 PF03999.12 PRP81948.1 - 0.00081 18.2 2.4 0.00083 18.2 2.4 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) GAS PF13851.6 PRP81948.1 - 0.00091 18.6 6.8 0.0011 18.3 6.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.9 PRP81948.1 - 0.00095 19.2 5.8 0.057 13.4 1.2 2.2 1 1 1 2 2 2 2 Axonemal dynein light chain IFT57 PF10498.9 PRP81948.1 - 0.0011 18.0 4.4 0.0012 17.9 4.4 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 FPP PF05911.11 PRP81948.1 - 0.0013 17.1 4.7 0.0013 17.0 4.7 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil FlaC_arch PF05377.11 PRP81948.1 - 0.0013 19.0 7.1 0.33 11.4 0.5 2.8 1 1 2 3 3 3 3 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 PRP81948.1 - 0.0014 18.7 4.9 0.0014 18.7 4.9 2.4 1 1 1 2 2 2 1 JNK-interacting protein leucine zipper II Troponin PF00992.20 PRP81948.1 - 0.0015 18.9 3.8 0.002 18.4 3.3 1.4 1 1 0 1 1 1 1 Troponin DUF4600 PF15372.6 PRP81948.1 - 0.0018 18.7 3.5 0.0019 18.6 3.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) HAP1_N PF04849.13 PRP81948.1 - 0.0025 17.1 5.9 0.0028 16.9 5.9 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region GCN5L1 PF06320.13 PRP81948.1 - 0.0026 17.9 2.5 0.0054 16.9 1.1 1.8 1 1 1 2 2 2 1 GCN5-like protein 1 (GCN5L1) DUF812 PF05667.11 PRP81948.1 - 0.0029 16.6 5.7 0.0037 16.2 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMPIT PF07851.13 PRP81948.1 - 0.0029 16.9 1.2 0.0037 16.6 1.2 1.0 1 0 0 1 1 1 1 TMPIT-like protein ADIP PF11559.8 PRP81948.1 - 0.0032 17.6 5.6 0.0047 17.0 5.6 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 PRP81948.1 - 0.0034 17.6 4.6 0.0054 17.0 4.6 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Tektin PF03148.14 PRP81948.1 - 0.0038 16.0 4.6 0.0051 15.6 4.3 1.5 1 1 0 1 1 1 1 Tektin family DUF1664 PF07889.12 PRP81948.1 - 0.0041 17.1 2.1 0.028 14.5 2.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Taxilin PF09728.9 PRP81948.1 - 0.0045 16.2 4.2 0.0058 15.8 4.2 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TolA_bind_tri PF16331.5 PRP81948.1 - 0.0046 17.0 6.2 0.11 12.6 1.7 3.0 1 1 1 2 2 2 1 TolA binding protein trimerisation Sec34 PF04136.15 PRP81948.1 - 0.0048 16.8 3.6 0.014 15.2 3.6 1.6 1 1 0 1 1 1 1 Sec34-like family Fmp27_WPPW PF10359.9 PRP81948.1 - 0.0055 15.6 4.0 0.0062 15.4 4.0 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF3552 PF12072.8 PRP81948.1 - 0.0056 16.1 6.6 0.042 13.3 6.9 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) ATG16 PF08614.11 PRP81948.1 - 0.0069 16.6 9.6 0.021 15.0 8.0 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Rab5-bind PF09311.11 PRP81948.1 - 0.0073 15.7 2.7 0.0095 15.4 2.7 1.1 1 0 0 1 1 1 1 Rabaptin-like protein Serine_rich PF08824.10 PRP81948.1 - 0.0075 16.3 1.6 0.053 13.5 0.2 2.0 1 1 1 2 2 2 1 Serine rich protein interaction domain Prefoldin_2 PF01920.20 PRP81948.1 - 0.0078 16.2 5.0 0.4 10.7 5.0 2.3 1 1 0 1 1 1 1 Prefoldin subunit YscO-like PF16789.5 PRP81948.1 - 0.0079 16.2 1.1 0.0096 16.0 1.1 1.2 1 0 0 1 1 1 1 YscO-like protein PspA_IM30 PF04012.12 PRP81948.1 - 0.008 15.8 2.2 0.013 15.1 2.2 1.3 1 0 0 1 1 1 1 PspA/IM30 family HMMR_N PF15905.5 PRP81948.1 - 0.0085 15.6 3.3 0.0094 15.5 3.3 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal CLZ PF16526.5 PRP81948.1 - 0.0089 16.4 6.9 0.078 13.4 2.6 2.8 1 1 2 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GIT_CC PF16559.5 PRP81948.1 - 0.0091 15.8 9.9 0.32 10.9 5.1 2.7 1 1 2 3 3 3 2 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 PRP81948.1 - 0.0099 15.9 11.2 0.28 11.3 0.5 3.0 1 1 3 4 4 4 2 Basic region leucine zipper TPR_MLP1_2 PF07926.12 PRP81948.1 - 0.01 15.9 9.7 0.21 11.7 1.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 PRP81948.1 - 0.011 16.2 5.0 0.012 16.1 5.0 1.0 1 0 0 1 1 1 0 Fez1 DUF4795 PF16043.5 PRP81948.1 - 0.011 15.3 3.8 0.024 14.2 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) BRE1 PF08647.11 PRP81948.1 - 0.012 15.7 6.3 0.017 15.2 6.3 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase HOOK PF05622.12 PRP81948.1 - 0.012 13.8 4.0 0.013 13.7 4.0 1.0 1 0 0 1 1 1 0 HOOK protein Seryl_tRNA_N PF02403.22 PRP81948.1 - 0.012 15.8 6.3 0.034 14.4 6.1 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SHE3 PF17078.5 PRP81948.1 - 0.013 15.2 8.8 0.031 14.0 8.8 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Tropomyosin_1 PF12718.7 PRP81948.1 - 0.014 15.6 7.1 0.028 14.6 6.6 1.7 1 1 1 2 2 2 0 Tropomyosin like NPV_P10 PF05531.12 PRP81948.1 - 0.014 15.8 2.2 0.36 11.3 1.0 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HemX PF04375.14 PRP81948.1 - 0.015 14.6 1.7 0.019 14.3 1.7 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase MbeD_MobD PF04899.12 PRP81948.1 - 0.017 15.2 2.9 0.16 12.1 0.3 2.3 1 1 1 2 2 2 0 MbeD/MobD like Not3 PF04065.15 PRP81948.1 - 0.017 14.5 2.3 0.019 14.4 2.3 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Wtap PF17098.5 PRP81948.1 - 0.019 14.9 5.5 0.13 12.2 5.5 1.9 1 1 0 1 1 1 0 WTAP/Mum2p family Lzipper-MIP1 PF14389.6 PRP81948.1 - 0.02 15.2 1.6 0.031 14.6 1.3 1.4 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF5082 PF16888.5 PRP81948.1 - 0.021 15.1 3.4 0.042 14.1 2.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) TMF_DNA_bd PF12329.8 PRP81948.1 - 0.022 14.8 10.3 0.026 14.5 8.9 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 PRP81948.1 - 0.022 13.4 3.1 0.023 13.3 3.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A BST2 PF16716.5 PRP81948.1 - 0.023 15.3 5.5 0.039 14.5 3.0 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 COG6 PF06419.11 PRP81948.1 - 0.026 12.8 6.1 0.089 11.0 1.5 2.0 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 Golgin_A5 PF09787.9 PRP81948.1 - 0.028 13.9 3.9 0.031 13.7 3.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Laminin_II PF06009.12 PRP81948.1 - 0.03 14.4 4.5 0.039 14.0 4.5 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF948 PF06103.11 PRP81948.1 - 0.03 14.6 1.3 1 9.7 1.3 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.10 PRP81948.1 - 0.031 14.6 2.1 0.046 14.0 2.1 1.4 1 0 0 1 1 1 0 Tup N-terminal DUF4200 PF13863.6 PRP81948.1 - 0.031 14.7 6.3 0.051 14.0 6.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) H-kinase_dim PF02895.14 PRP81948.1 - 0.034 14.5 5.2 0.17 12.3 5.2 2.1 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Snapin_Pallidin PF14712.6 PRP81948.1 - 0.035 14.5 6.0 0.14 12.6 5.5 2.0 1 1 0 1 1 1 0 Snapin/Pallidin Prefoldin PF02996.17 PRP81948.1 - 0.035 14.0 3.2 1.1 9.1 0.3 2.7 1 1 1 2 2 2 0 Prefoldin subunit YabA PF06156.13 PRP81948.1 - 0.037 14.7 7.3 0.13 12.9 7.3 2.0 1 1 0 1 1 1 0 Initiation control protein YabA Spc42p PF11544.8 PRP81948.1 - 0.04 13.9 8.0 2 8.5 5.3 2.3 1 1 1 2 2 2 0 Spindle pole body component Spc42p MCC-bdg_PDZ PF10506.9 PRP81948.1 - 0.04 13.9 5.6 4.4 7.4 1.2 3.3 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Atg14 PF10186.9 PRP81948.1 - 0.047 12.8 2.3 0.05 12.7 2.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nsp1_C PF05064.13 PRP81948.1 - 0.049 13.4 3.9 0.98 9.2 0.6 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region Rootletin PF15035.6 PRP81948.1 - 0.052 13.6 7.6 0.12 12.4 7.6 1.7 1 1 1 2 2 1 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.8 PRP81948.1 - 0.055 13.7 7.4 0.54 10.5 6.1 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Sigma70_ner PF04546.13 PRP81948.1 - 0.062 13.2 6.7 0.02 14.8 4.0 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region Nnf1 PF03980.14 PRP81948.1 - 0.071 13.5 7.8 1.6 9.1 0.7 2.7 1 1 1 2 2 2 0 Nnf1 Mod_r PF07200.13 PRP81948.1 - 0.074 13.2 5.2 0.13 12.4 5.2 1.5 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF2205 PF10224.9 PRP81948.1 - 0.09 12.8 3.6 0.7 9.9 1.1 2.3 1 1 1 2 2 2 0 Short coiled-coil protein TSC22 PF01166.18 PRP81948.1 - 0.11 12.8 6.8 4.4 7.7 0.1 3.1 1 1 1 2 2 2 0 TSC-22/dip/bun family Exonuc_VII_L PF02601.15 PRP81948.1 - 0.11 12.0 4.4 0.11 12.0 4.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lectin_N PF03954.14 PRP81948.1 - 0.12 12.1 5.4 0.3 10.8 5.4 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain PI3K_P85_iSH2 PF16454.5 PRP81948.1 - 0.13 11.9 8.0 1.2 8.7 2.6 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CENP-F_leu_zip PF10473.9 PRP81948.1 - 0.13 12.3 7.9 0.25 11.4 7.9 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PLAC9 PF15205.6 PRP81948.1 - 0.13 12.7 0.1 0.98 9.9 0.1 2.1 1 1 0 2 2 2 0 Placenta-specific protein 9 UPF0242 PF06785.11 PRP81948.1 - 0.15 12.2 3.6 0.18 11.9 3.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NRBF2 PF08961.10 PRP81948.1 - 0.15 11.6 5.3 0.22 11.1 4.7 1.6 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DUF5340 PF17275.2 PRP81948.1 - 0.16 12.1 0.3 0.27 11.4 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5340) DUF4988 PF16378.5 PRP81948.1 - 0.16 11.6 4.7 3.8 7.2 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function DASH_Dam1 PF08653.10 PRP81948.1 - 0.16 11.8 7.9 4 7.3 1.2 3.0 1 1 3 4 4 4 0 DASH complex subunit Dam1 V_ATPase_I PF01496.19 PRP81948.1 - 0.22 9.4 3.7 0.24 9.3 3.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FadA PF09403.10 PRP81948.1 - 0.23 11.9 4.9 0.24 11.9 1.9 2.1 1 1 1 2 2 2 0 Adhesion protein FadA Sec20 PF03908.13 PRP81948.1 - 0.25 11.3 3.9 0.31 11.0 1.2 2.0 1 1 1 2 2 2 0 Sec20 Prominin PF05478.11 PRP81948.1 - 0.29 9.0 4.6 0.65 7.9 4.7 1.5 1 1 0 1 1 1 0 Prominin Swi5 PF07061.11 PRP81948.1 - 0.29 11.2 3.0 6.5 6.9 2.3 2.2 1 1 1 2 2 2 0 Swi5 betaPIX_CC PF16523.5 PRP81948.1 - 0.29 11.0 4.3 3.6 7.5 1.4 2.4 1 1 2 3 3 3 0 betaPIX coiled coil HAUS-augmin3 PF14932.6 PRP81948.1 - 0.3 10.6 5.2 0.39 10.2 5.0 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fungal_TACC PF12709.7 PRP81948.1 - 0.31 11.5 4.4 4.3 7.9 1.0 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4407 PF14362.6 PRP81948.1 - 0.33 10.2 2.0 0.42 9.9 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4763 PF15960.5 PRP81948.1 - 0.62 9.3 6.4 1.3 8.2 4.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Fib_alpha PF08702.10 PRP81948.1 - 0.65 10.2 5.3 1 9.5 5.1 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIVA PF05103.13 PRP81948.1 - 0.65 10.1 6.3 1.6 8.8 2.2 2.0 1 1 1 2 2 2 0 DivIVA protein UPF0184 PF03670.13 PRP81948.1 - 0.73 10.3 11.6 0.73 10.3 1.1 3.2 2 1 2 4 4 3 0 Uncharacterised protein family (UPF0184) DUF5595 PF18077.1 PRP81948.1 - 0.79 9.8 5.2 1.5 9.0 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) MctB PF11382.8 PRP81948.1 - 0.89 9.2 4.9 3.6 7.2 2.5 2.4 1 1 1 2 2 2 0 Copper transport outer membrane protein, MctB Cep57_CLD_2 PF14197.6 PRP81948.1 - 0.92 9.6 11.1 0.54 10.4 9.2 1.6 2 0 0 2 2 1 0 Centrosome localisation domain of PPC89 Fzo_mitofusin PF04799.13 PRP81948.1 - 0.92 9.0 4.2 1.8 8.1 4.2 1.6 1 1 0 1 1 1 0 fzo-like conserved region Spc24 PF08286.11 PRP81948.1 - 1.8 8.8 10.2 62 3.9 10.2 2.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 EMP24_GP25L PF01105.24 PRP81948.1 - 1.9 8.4 6.6 6 6.8 1.8 2.1 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD KxDL PF10241.9 PRP81948.1 - 2 8.7 8.7 5.1 7.4 3.5 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein Uso1_p115_C PF04871.13 PRP81948.1 - 6.6 7.1 12.5 23 5.4 12.3 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region XRN_N PF03159.18 PRP81949.1 - 6.6e-37 127.2 0.0 1.1e-36 126.6 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PRP81949.1 - 0.0004 19.5 0.5 0.0079 15.2 0.2 2.3 2 0 0 2 2 2 1 Xrn1 helical domain Telomere_reg-2 PF10193.9 PRP81950.1 - 1.5e-11 44.7 2.5 5.9e-11 42.8 0.9 2.8 3 0 0 3 3 3 1 Telomere length regulation protein CPSF100_C PF13299.6 PRP81950.1 - 0.5 10.5 3.6 0.9 9.7 3.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 PRP81950.1 - 1.2 9.4 9.9 2.8 8.3 9.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FPN1 PF06963.12 PRP81951.1 - 3.5e-79 266.4 19.4 2.3e-77 260.4 19.4 2.2 1 1 0 1 1 1 1 Ferroportin1 (FPN1) Abhydrolase_1 PF00561.20 PRP81952.1 - 2.1e-23 83.3 0.1 5.1e-23 82.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP81952.1 - 1.3e-15 58.6 2.3 2e-15 58.0 2.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_23 PF13489.6 PRP81952.1 - 4e-14 52.8 0.0 8.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP81952.1 - 5.2e-13 49.5 0.0 3.6e-12 46.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Hydrolase_4 PF12146.8 PRP81952.1 - 1.3e-12 47.5 0.0 3.2e-12 46.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Methyltransf_12 PF08242.12 PRP81952.1 - 2.7e-12 47.3 0.0 7.4e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP81952.1 - 1.2e-10 41.8 0.0 3.8e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP81952.1 - 1.6e-10 41.0 0.0 1.5e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 PRP81952.1 - 1.6e-05 24.3 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 PRP81952.1 - 0.00072 19.1 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PRP81952.1 - 0.0063 15.9 0.0 0.017 14.4 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 PRP81952.1 - 0.042 13.6 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_4 PF02390.17 PRP81952.1 - 0.14 11.6 0.0 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Kinesin PF00225.23 PRP81953.1 - 4.5e-109 364.4 0.6 4.5e-109 364.4 0.6 3.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP81953.1 - 8.4e-26 90.7 0.0 6.2e-25 87.9 0.0 2.7 1 0 0 1 1 1 1 Microtubule binding eIF-4B PF06273.11 PRP81953.1 - 0.0013 17.9 7.7 0.0013 17.9 7.7 7.1 6 1 2 8 8 8 1 Plant specific eukaryotic initiation factor 4B Peptidase_S8 PF00082.22 PRP81954.1 - 3e-83 279.5 0.3 5.2e-83 278.7 0.3 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 PRP81954.1 - 1.1e-52 178.3 0.8 2.2e-52 177.3 0.8 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II Ank_2 PF12796.7 PRP81956.1 - 9.7e-21 74.2 4.4 4.1e-11 43.3 0.6 4.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP81956.1 - 1.1e-12 46.9 2.7 0.00027 21.2 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 PRP81956.1 - 1.7e-11 44.0 3.5 8.4e-07 29.2 0.0 5.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 PRP81956.1 - 1.3e-10 41.5 2.9 1.2e-08 35.4 0.1 3.9 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP81956.1 - 4.2e-10 39.7 1.8 3.1e-05 24.1 0.1 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) F-box PF00646.33 PRP81956.1 - 0.031 14.2 0.4 0.11 12.4 0.4 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 PRP81956.1 - 0.12 12.3 6.4 0.087 12.7 3.4 2.5 2 0 0 2 2 2 0 F-box-like Glyco_hydro_16 PF00722.21 PRP81957.1 - 2.9e-19 69.2 1.8 2.9e-19 69.2 1.8 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MGC-24 PF05283.11 PRP81957.1 - 1.5 9.3 8.1 2.5 8.6 7.1 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SET PF00856.28 PRP81958.1 - 5.5e-22 78.9 0.3 5.5e-22 78.9 0.3 2.6 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.16 PRP81958.1 - 1.9e-07 31.7 5.5 1.9e-07 31.7 5.5 3.5 2 2 0 2 2 2 1 Pre-SET motif Pex24p PF06398.11 PRP81958.1 - 0.12 11.4 0.2 0.26 10.2 0.2 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Utp8 PF10395.9 PRP81958.1 - 0.17 10.4 4.2 0.23 9.9 4.2 1.1 1 0 0 1 1 1 0 Utp8 family UPF0242 PF06785.11 PRP81958.1 - 1.8 8.7 7.5 0.39 10.8 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_C1 PF00112.23 PRP81959.1 - 1.1e-44 153.2 6.1 1.6e-44 152.6 6.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP81959.1 - 1.5e-10 41.3 2.0 2.4e-10 40.7 2.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Propeptide_C1 PF08127.13 PRP81959.1 - 4e-07 29.8 0.3 9.4e-07 28.6 0.3 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 PRP81959.1 - 0.054 12.3 0.1 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family RecQ_Zn_bind PF16124.5 PRP81961.1 - 1.6e-11 44.8 1.3 4.9e-11 43.2 1.3 1.8 1 0 0 1 1 1 1 RecQ zinc-binding KH_6 PF15985.5 PRP81961.1 - 0.091 13.1 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 KH domain DUF4955 PF16315.5 PRP81962.1 - 3.8e-06 27.2 0.1 4.3e-06 27.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4955) Latrotoxin_C PF15658.6 PRP81962.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Latrotoxin C-terminal domain adh_short PF00106.25 PRP81963.1 - 3.1e-43 147.5 0.1 5.4e-43 146.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP81963.1 - 6.8e-28 97.8 0.1 1e-27 97.2 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WWE PF02825.20 PRP81963.1 - 1.5e-11 44.7 1.7 4.6e-11 43.2 1.7 1.9 1 0 0 1 1 1 1 WWE domain KR PF08659.10 PRP81963.1 - 3.2e-07 30.4 0.3 1.7e-06 28.1 0.3 2.0 1 1 0 1 1 1 1 KR domain Linker_histone PF00538.19 PRP81963.1 - 1.3e-06 28.6 0.1 2.9e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF1776 PF08643.10 PRP81963.1 - 4.3e-06 26.3 0.0 6.3e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 PRP81963.1 - 0.082 12.8 2.1 0.53 10.1 1.0 2.5 1 1 1 2 2 2 0 NAD(P)H-binding Nop25 PF09805.9 PRP81964.1 - 1.4e-22 80.6 19.6 1.4e-22 80.6 19.6 2.5 2 2 0 2 2 2 1 Nucleolar protein 12 (25kDa) Glyco_transf_54 PF04666.13 PRP81965.1 - 2.3e-23 82.5 0.0 5.3e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF1201 PF06716.11 PRP81965.1 - 0.11 12.5 2.8 0.26 11.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Ank_2 PF12796.7 PRP81966.1 - 0.0029 18.1 0.0 0.0039 17.8 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP81966.1 - 0.021 15.1 0.0 0.36 11.2 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP81966.1 - 0.033 14.7 0.0 0.26 12.0 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 PRP81966.1 - 0.08 13.6 0.0 0.34 11.6 0.0 1.9 1 1 1 2 2 2 0 Ankyrin repeats (many copies) SPRY PF00622.28 PRP81967.1 - 3.6e-10 40.0 0.0 4.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 SPRY domain DUF4955 PF16315.5 PRP81968.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) Ank_2 PF12796.7 PRP81969.1 - 0.052 14.1 0.0 0.076 13.6 0.0 1.3 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Sugar_tr PF00083.24 PRP81970.1 - 7.3e-104 348.1 19.4 8.3e-104 347.9 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP81970.1 - 4.6e-27 94.9 38.9 1.5e-13 50.5 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 PRP81970.1 - 0.016 14.9 2.2 0.016 14.9 2.2 2.8 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 pPIWI_RE_X PF13111.6 PRP81970.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 pPIWI_RE module N-terminal domain Ytca PF17090.5 PRP81970.1 - 0.59 10.7 7.3 1.7 9.2 0.2 3.5 3 0 0 3 3 3 0 Uncharacterised protein family Pectate_lyase_3 PF12708.7 PRP81972.1 - 0.014 15.3 8.1 0.051 13.4 4.1 2.9 2 1 0 2 2 2 0 Pectate lyase superfamily protein DUF4955 PF16315.5 PRP81972.1 - 0.023 14.9 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) Patatin PF01734.22 PRP81973.1 - 9.5e-13 48.8 1.7 1.6e-11 44.8 0.3 2.9 2 1 0 2 2 2 1 Patatin-like phospholipase TPR_12 PF13424.6 PRP81973.1 - 3.8e-05 23.9 5.6 0.013 15.8 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP81973.1 - 0.00021 21.7 0.5 0.071 13.6 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.31 PRP81973.1 - 0.00036 20.6 0.1 0.0011 19.1 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain ANAPC3 PF12895.7 PRP81973.1 - 0.0022 18.2 0.5 0.91 9.8 0.1 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4375 PF14300.6 PRP81973.1 - 0.029 14.6 0.3 0.18 12.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) CLAG PF03805.13 PRP81973.1 - 0.09 10.3 0.5 0.13 9.8 0.5 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Phage_holin_3_6 PF07332.11 PRP81973.1 - 0.093 12.8 2.8 0.22 11.6 2.8 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TPR_10 PF13374.6 PRP81973.1 - 0.13 12.1 0.7 2.5 8.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP81973.1 - 0.29 11.8 1.4 0.77 10.5 1.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP81973.1 - 0.6 10.0 3.7 15 5.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_2 PF13646.6 PRP81974.1 - 7.8e-09 35.8 2.3 0.47 10.9 0.0 6.9 5 2 2 7 7 7 4 HEAT repeats HEAT PF02985.22 PRP81974.1 - 2.1e-07 30.6 13.0 0.84 10.1 0.1 8.3 7 1 1 8 8 8 3 HEAT repeat NLRC4_HD2 PF17776.1 PRP81974.1 - 0.25 11.9 3.4 0.49 10.9 0.1 2.8 3 0 0 3 3 3 0 NLRC4 helical domain HD2 Yop-YscD_cpl PF16697.5 PRP81975.1 - 0.037 14.3 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain SNF2_N PF00176.23 PRP81976.1 - 1.1e-60 205.2 1.2 2.5e-60 204.1 1.2 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP81976.1 - 1.3e-19 70.6 0.0 4.6e-19 68.8 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 PRP81976.1 - 6.5e-18 64.4 2.0 5.4e-08 32.6 0.1 3.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 PRP81976.1 - 8.1e-10 39.0 0.1 8.1e-10 39.0 0.1 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CHDCT2 PF08074.11 PRP81976.1 - 1.4e-09 38.4 0.3 6.5e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain DUF1087 PF06465.13 PRP81976.1 - 3.4e-08 33.4 0.2 3.4e-08 33.4 0.2 4.0 3 1 0 3 3 2 1 Domain of Unknown Function (DUF1087) PHD PF00628.29 PRP81976.1 - 1.8e-07 31.0 6.9 3.4e-07 30.0 6.9 1.5 1 0 0 1 1 1 1 PHD-finger DEAD PF00270.29 PRP81976.1 - 5.8e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1086 PF06461.11 PRP81976.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Zf_RING PF16744.5 PRP81976.1 - 0.021 14.9 1.7 0.048 13.8 1.7 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger AAA_22 PF13401.6 PRP81976.1 - 0.032 14.5 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain CTD_bind PF04818.13 PRP81977.1 - 1.3e-05 26.0 0.0 5.7e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. zf_UBZ PF18439.1 PRP81977.1 - 0.012 15.2 0.4 0.012 15.2 0.4 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Zn-C2H2_12 PF18112.1 PRP81977.1 - 0.22 12.0 2.1 0.3 11.6 0.1 2.4 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 PRP81977.1 - 0.28 12.1 1.7 6.7 7.8 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Cornichon PF03311.14 PRP81978.1 - 6.3e-38 129.8 8.7 7.4e-38 129.6 8.7 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2045 PF09741.9 PRP81979.1 - 6e-38 130.5 0.9 2.1e-36 125.5 0.9 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) NUDE_C PF04880.13 PRP81979.1 - 0.056 13.9 4.9 0.45 11.0 2.8 2.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region EF-hand_1 PF00036.32 PRP81980.1 - 5e-25 85.1 7.1 2.3e-06 26.7 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PRP81980.1 - 1.2e-23 83.3 4.6 2.8e-13 50.1 0.4 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP81980.1 - 1.6e-21 74.4 3.5 4.3e-05 23.1 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PRP81980.1 - 3.2e-15 54.8 8.8 0.0005 19.4 0.0 4.7 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 PRP81980.1 - 6.4e-13 48.3 5.2 0.00057 19.7 0.3 4.0 3 2 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP81980.1 - 2.9e-10 40.5 0.5 0.00011 22.4 0.2 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PRP81980.1 - 6.6e-06 26.0 2.7 0.039 13.9 0.1 3.5 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 PRP81980.1 - 0.057 13.6 2.1 20 5.4 2.0 3.0 2 1 0 2 2 2 0 Dockerin type I domain EF-hand_9 PF14658.6 PRP81980.1 - 0.082 13.2 0.0 8.4 6.8 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain Glyco_trans_1_3 PF13528.6 PRP81981.1 - 0.00014 21.2 0.4 0.24 10.6 0.0 2.8 3 1 0 3 3 3 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.16 PRP81981.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain LCAT PF02450.15 PRP81982.1 - 4.9e-31 108.3 0.0 1.6e-29 103.3 0.0 2.1 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 PRP81982.1 - 9.6e-07 28.3 0.0 2.1e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 PRP81982.1 - 0.00074 19.1 0.0 0.0021 17.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Palm_thioest PF02089.15 PRP81982.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 PRP81982.1 - 0.011 16.3 0.0 0.02 15.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 PRP81982.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF3385 PF11865.8 PRP81983.1 - 0.46 10.4 7.8 1.7 8.5 0.7 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF3385) CCDC14 PF15254.6 PRP81984.1 - 6.1 5.4 6.0 9.6 4.7 0.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 Ins_P5_2-kin PF06090.12 PRP81985.1 - 1.4e-67 228.5 0.0 2.9e-67 227.4 0.0 1.5 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Amidohydro_1 PF01979.20 PRP81986.1 - 3.9e-42 144.8 0.0 1e-35 123.7 0.0 2.0 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 PRP81986.1 - 1.6e-06 27.9 0.2 3.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family A_deaminase PF00962.22 PRP81986.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase DUF1996 PF09362.10 PRP81987.1 - 2e-73 247.3 1.3 3.4e-73 246.5 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Es2 PF09751.9 PRP81987.1 - 8.2e-62 210.3 19.0 9.2e-33 114.6 4.9 3.9 1 1 2 3 3 3 2 Nuclear protein Es2 Fascin PF06268.13 PRP81987.1 - 7.5e-09 35.8 0.2 0.008 16.4 0.0 4.1 3 1 1 4 4 4 2 Fascin domain FRG1 PF06229.12 PRP81987.1 - 1.2e-07 31.7 0.4 0.011 15.4 0.0 3.5 2 1 1 3 3 3 3 FRG1-like domain RicinB_lectin_2 PF14200.6 PRP81987.1 - 3.1e-05 24.6 5.7 0.072 13.8 0.4 2.9 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like FGF PF00167.18 PRP81987.1 - 0.1 12.7 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Fibroblast growth factor Thioredoxin_8 PF13905.6 PRP81988.1 - 1.5e-32 111.8 0.0 2.6e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like PITH PF06201.13 PRP81988.1 - 2.1e-30 106.0 0.2 3.8e-30 105.1 0.1 1.5 2 0 0 2 2 2 1 PITH domain AhpC-TSA PF00578.21 PRP81988.1 - 6.8e-10 38.9 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 PRP81988.1 - 8.4e-10 38.6 0.0 6.2e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 PRP81988.1 - 5.6e-09 36.4 0.0 1.2e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 PRP81988.1 - 3.1e-08 33.5 0.0 5.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 PRP81988.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_9 PF14595.6 PRP81988.1 - 0.003 17.3 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 PRP81988.1 - 0.0077 16.4 0.1 0.02 15.1 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 PRP81988.1 - 0.012 15.8 0.3 0.12 12.6 0.0 2.6 2 1 0 2 2 2 0 Glutaredoxin TraF PF13728.6 PRP81988.1 - 0.044 13.6 0.1 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 PRP81988.1 - 0.051 13.5 0.0 1.8 8.5 0.0 2.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE GMC_oxred_N PF00732.19 PRP81989.1 - 1.6e-50 172.2 0.0 5.1e-26 91.7 0.0 4.2 4 0 0 4 4 4 4 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP81989.1 - 5.3e-27 95.1 0.0 1.3e-26 93.9 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 PRP81989.1 - 8.9e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PRP81989.1 - 0.0054 16.0 0.0 0.06 12.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PRP81989.1 - 0.0068 15.7 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 PRP81989.1 - 0.013 15.7 0.0 0.043 14.1 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SAC3_GANP PF03399.16 PRP81992.1 - 6.1e-18 65.2 7.1 4.9e-16 59.0 7.1 2.1 1 1 0 1 1 1 1 SAC3/GANP family Kinesin PF00225.23 PRP81993.1 - 2.4e-118 394.9 0.4 4.5e-118 394.0 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP81993.1 - 4.8e-27 94.7 2.1 5.9e-27 94.4 0.0 2.3 2 1 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 PRP81993.1 - 0.28 11.3 15.1 6.6 6.8 15.1 2.5 1 1 0 1 1 1 0 Kinesin-associated DUF600 PF04634.12 PRP81993.1 - 3.7 7.6 7.5 0.24 11.4 1.1 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF600 MOZ_SAS PF01853.18 PRP81994.1 - 9.4e-88 292.6 0.8 1.4e-87 291.9 0.8 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PRP81994.1 - 8.4e-28 95.8 4.4 8.4e-28 95.8 4.4 2.5 3 0 0 3 3 3 1 MYST family zinc finger domain Tudor-knot PF11717.8 PRP81994.1 - 4.6e-15 55.3 4.7 8.1e-10 38.4 0.2 2.8 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 PRP81994.1 - 0.0026 18.2 0.0 0.0052 17.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP81994.1 - 0.0053 17.0 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HTH_11 PF08279.12 PRP81994.1 - 0.11 12.4 0.4 0.3 11.0 0.4 1.7 1 0 0 1 1 1 0 HTH domain DDRGK PF09756.9 PRP81994.1 - 0.25 10.9 8.8 3.3 7.3 0.1 2.3 2 0 0 2 2 2 0 DDRGK domain zf-CXXC PF02008.20 PRP81994.1 - 0.29 11.2 3.1 1.7 8.7 3.2 2.3 2 0 0 2 2 2 0 CXXC zinc finger domain zf-A20 PF01754.16 PRP81995.1 - 1.2e-08 34.8 11.0 1.2e-08 34.8 11.0 1.9 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 PRP81995.1 - 2e-08 34.2 10.4 2e-08 34.2 10.4 1.8 2 0 0 2 2 2 1 AN1-like Zinc finger Ead_Ea22 PF13935.6 PRP81995.1 - 0.13 12.9 0.1 0.19 12.4 0.1 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein DUF4955 PF16315.5 PRP81996.1 - 0.00083 19.6 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4955) DUF3105 PF11303.8 PRP81997.1 - 0.038 14.1 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) Spc42p PF11544.8 PRP81997.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.5 2 0 0 2 2 2 0 Spindle pole body component Spc42p TMCO5 PF14992.6 PRP81997.1 - 6.2 6.3 9.2 0.28 10.7 0.7 2.4 3 0 0 3 3 3 0 TMCO5 family Rogdi_lz PF10259.9 PRP81998.1 - 2.9e-13 49.9 0.0 3.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein IL3 PF02059.15 PRP81998.1 - 0.021 14.8 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Interleukin-3 ERCC4 PF02732.15 PRP82001.1 - 1.6e-19 70.7 0.0 4.5e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain Csm1_N PF18504.1 PRP82002.1 - 0.0013 19.0 5.2 0.073 13.4 0.2 2.6 2 0 0 2 2 2 1 Csm1 N-terminal domain KASH_CCD PF14662.6 PRP82002.1 - 0.0016 18.3 7.4 0.0021 17.9 7.4 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 PRP82002.1 - 0.0096 16.2 7.5 0.54 10.6 1.4 2.8 1 1 1 2 2 2 2 TSC-22/dip/bun family DivIC PF04977.15 PRP82002.1 - 0.013 15.3 10.6 0.13 12.0 1.7 2.3 1 1 1 2 2 2 0 Septum formation initiator ATG16 PF08614.11 PRP82002.1 - 0.022 15.0 11.0 0.029 14.6 11.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 PRP82002.1 - 0.026 13.8 7.2 0.036 13.4 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Swi5 PF07061.11 PRP82002.1 - 0.028 14.5 4.5 0.21 11.7 0.8 2.4 2 0 0 2 2 2 0 Swi5 Anti-adapt_IraP PF10796.9 PRP82002.1 - 0.04 14.5 4.6 3.5 8.3 0.5 2.6 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein UPF0242 PF06785.11 PRP82002.1 - 0.045 13.8 10.2 0.22 11.6 10.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mto2_bdg PF12808.7 PRP82002.1 - 0.063 13.6 15.0 0.47 10.8 4.3 2.5 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ABC_tran_CTD PF16326.5 PRP82002.1 - 0.064 13.5 12.0 0.33 11.3 3.2 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 PRP82002.1 - 0.11 13.2 8.1 1 10.0 1.1 2.5 2 0 0 2 2 2 0 SlyX DNA_gyraseB PF00204.25 PRP82002.1 - 0.15 11.5 1.0 7 6.1 0.0 2.1 1 1 1 2 2 2 0 DNA gyrase B TMPIT PF07851.13 PRP82002.1 - 0.18 11.0 4.3 0.23 10.6 4.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Macoilin PF09726.9 PRP82002.1 - 0.25 9.9 5.9 0.25 9.9 5.9 1.0 1 0 0 1 1 1 0 Macoilin family DUF2316 PF10078.9 PRP82002.1 - 0.25 11.6 3.6 7.9 6.8 2.4 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) DUF4200 PF13863.6 PRP82002.1 - 0.27 11.6 10.5 0.78 10.1 10.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.11 PRP82002.1 - 0.37 11.2 5.4 2.2 8.7 0.5 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIVA PF05103.13 PRP82002.1 - 0.39 10.8 5.9 1.9 8.6 0.6 2.3 1 1 1 2 2 2 0 DivIVA protein bZIP_2 PF07716.15 PRP82002.1 - 0.54 10.4 11.0 1.4 9.1 2.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper KIAA1430 PF13879.6 PRP82002.1 - 0.58 11.0 10.8 0.58 10.9 1.4 2.3 1 1 2 3 3 3 0 KIAA1430 homologue YabA PF06156.13 PRP82002.1 - 0.7 10.6 8.7 3.8 8.2 1.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA BBP1_C PF15272.6 PRP82002.1 - 0.92 9.3 8.6 0.19 11.5 2.3 2.0 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal ZapB PF06005.12 PRP82002.1 - 0.94 10.0 14.1 3.6 8.1 4.6 2.5 1 1 1 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 PRP82002.1 - 0.95 9.9 9.2 1.9 8.9 9.2 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) YwqJ-deaminase PF14431.6 PRP82002.1 - 2.1 8.5 5.4 5.3 7.2 2.1 2.1 1 1 1 2 2 2 0 YwqJ-like deaminase Fungal_TACC PF12709.7 PRP82002.1 - 2.2 8.8 5.9 5.9 7.4 1.0 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins FUSC PF04632.12 PRP82002.1 - 2.9 6.3 5.6 3.5 6.0 5.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family NYD-SP28_assoc PF14775.6 PRP82002.1 - 3.3 7.9 8.3 15 5.8 0.6 3.1 2 1 0 2 2 2 0 Sperm tail C-terminal domain APG6_N PF17675.1 PRP82002.1 - 5.9 7.4 13.2 62 4.1 11.7 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region UPF0183 PF03676.14 PRP82003.1 - 1e-116 390.5 1.6 1.2e-116 390.2 1.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) SRP_SPB PF02978.19 PRP82004.1 - 2.2e-14 53.8 0.1 6.2e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Signal peptide binding domain CBP_BcsO PF17037.5 PRP82004.1 - 0.022 14.9 5.1 0.044 13.9 5.1 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Uricase PF01014.18 PRP82005.1 - 2.2e-60 202.6 0.1 1.2e-31 109.7 0.0 2.2 2 0 0 2 2 2 2 Uricase Ank_2 PF12796.7 PRP82006.1 - 1.9e-40 137.3 5.0 1.9e-10 41.2 0.0 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82006.1 - 1.8e-13 50.7 2.8 0.00023 21.7 0.0 4.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP82006.1 - 1.2e-12 47.7 2.7 0.0029 18.0 0.1 6.3 3 1 3 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PRP82006.1 - 6.3e-08 32.7 1.2 1.5 9.2 0.0 5.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82006.1 - 1.1e-07 31.6 1.9 5.9 7.8 0.0 7.1 8 0 0 8 8 8 2 Ankyrin repeat PPR_3 PF13812.6 PRP82007.1 - 9e-22 76.9 5.1 8.4e-07 29.0 0.4 3.7 2 1 0 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 PRP82007.1 - 2.4e-18 66.0 4.7 7e-05 22.9 0.1 5.6 1 1 5 6 6 6 6 PPR repeat family PPR_long PF17177.4 PRP82007.1 - 1.1e-10 41.3 0.9 0.00018 20.9 0.1 3.4 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PRP82007.1 - 1.3e-06 28.2 10.9 0.75 10.2 0.0 6.0 6 1 0 6 6 6 3 PPR repeat Ufm1 PF03671.14 PRP82007.1 - 0.00062 19.8 0.0 0.0034 17.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin fold modifier 1 protein Troponin PF00992.20 PRP82007.1 - 0.005 17.1 2.2 0.005 17.1 2.2 2.5 2 1 1 3 3 3 1 Troponin DUF3368 PF11848.8 PRP82007.1 - 0.008 15.9 0.1 0.14 11.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3368) PPR_1 PF12854.7 PRP82007.1 - 0.012 15.3 0.9 4.3 7.1 0.0 3.9 3 1 0 3 3 3 0 PPR repeat PX PF00787.24 PRP82007.1 - 0.016 15.2 1.3 0.025 14.6 0.4 1.8 2 0 0 2 2 2 0 PX domain SPOB_a PF14689.6 PRP82007.1 - 0.055 13.2 0.5 0.68 9.7 0.0 2.9 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Tyrosinase PF00264.20 PRP82007.1 - 0.056 13.7 0.7 0.11 12.8 0.7 1.5 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF2420 PF10336.9 PRP82007.1 - 0.065 13.3 1.4 5.8 7.0 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2420) Drf_DAD PF06345.11 PRP82007.1 - 1.2 9.3 3.5 1.4 9.1 0.6 2.2 2 0 0 2 2 2 0 DRF Autoregulatory Domain Carb_bind PF10645.9 PRP82009.1 - 0.016 15.4 11.9 0.016 15.4 11.9 3.3 3 1 1 4 4 4 0 Carbohydrate binding SIR2 PF02146.17 PRP82010.1 - 9.8e-29 100.5 0.0 3.3e-26 92.3 0.0 2.3 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 PRP82010.1 - 0.00063 19.5 0.0 0.81 9.4 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain COG2 PF06148.11 PRP82011.1 - 5.1e-32 110.8 2.0 5.1e-32 110.8 2.0 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 PRP82011.1 - 2.8e-22 79.5 4.7 3.1e-21 76.1 0.6 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 PRP82011.1 - 0.00031 20.8 4.7 0.00065 19.7 0.1 3.1 3 0 0 3 3 3 1 Vps51/Vps67 DUF1664 PF07889.12 PRP82011.1 - 0.19 11.8 9.2 0.44 10.6 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Baculo_FP PF03258.14 PRP82012.1 - 0.044 13.9 0.1 0.089 12.9 0.1 1.4 1 0 0 1 1 1 0 Baculovirus FP protein Glucodextran_C PF09985.9 PRP82014.1 - 0.049 13.1 0.1 0.086 12.3 0.1 1.3 1 0 0 1 1 1 0 C-terminal binding-module, SLH-like, of glucodextranase DUF3040 PF11239.8 PRP82014.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF1631 PF07793.11 PRP82014.1 - 9.5 4.5 13.1 1.3e+02 0.7 13.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1918 PF08940.11 PRP82016.1 - 0.0067 16.0 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1918) Peptidase_S68 PF10461.9 PRP82016.1 - 0.02 15.1 0.7 0.89 9.8 0.1 2.9 2 0 0 2 2 2 0 Peptidase S68 Myb_DNA-binding PF00249.31 PRP82020.1 - 6.6e-52 173.5 36.5 1.1e-15 57.5 0.3 6.9 6 1 0 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP82020.1 - 1.3e-45 153.4 15.8 2.6e-14 53.2 0.1 6.5 3 1 4 7 7 7 5 Myb-like DNA-binding domain SLIDE PF09111.10 PRP82020.1 - 6.2e-06 26.2 19.7 0.039 14.0 0.0 6.7 3 2 5 8 8 8 3 SLIDE Myb_DNA-bind_4 PF13837.6 PRP82020.1 - 0.055 13.8 23.1 0.49 10.8 0.2 6.8 4 1 2 6 6 6 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 PRP82020.1 - 0.065 13.4 0.2 0.91 9.7 0.0 3.1 4 0 0 4 4 4 0 Rap1 Myb domain Bestrophin PF01062.21 PRP82020.1 - 0.13 11.6 0.6 0.24 10.8 0.6 1.5 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel SANT_DAMP1_like PF16282.5 PRP82020.1 - 0.33 11.2 12.6 2.4 8.4 0.0 5.6 5 1 2 7 7 7 0 SANT/Myb-like domain of DAMP1 RrnaAD PF00398.20 PRP82021.1 - 1.9e-56 191.1 0.0 2.7e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 PRP82021.1 - 3.1e-07 31.0 0.0 7.9e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP82021.1 - 1.3e-05 25.7 0.0 5.6e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP82021.1 - 0.00027 21.6 0.0 0.00068 20.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain NodS PF05401.11 PRP82021.1 - 0.0013 18.4 0.0 0.0042 16.7 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 PRP82021.1 - 0.0021 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PRP82021.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 PRP82021.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.12 PRP82021.1 - 0.041 13.0 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 PRP82021.1 - 0.049 13.2 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.7 PRP82021.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 PRP82021.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_31 PF13847.6 PRP82021.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Solute_trans_a PF03619.16 PRP82022.1 - 0.028 14.0 0.1 0.028 14.0 0.1 1.1 1 0 0 1 1 1 0 Organic solute transporter Ostalpha DUF2048 PF09752.9 PRP82022.1 - 0.07 12.2 0.4 0.082 12.0 0.4 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Spt5-NGN PF03439.13 PRP82026.1 - 1.5e-20 72.9 0.0 3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 PRP82026.1 - 7.7e-11 41.6 28.4 0.0001 22.1 0.0 7.3 8 1 0 8 8 8 3 KOW motif Spt5_N PF11942.8 PRP82026.1 - 0.00026 21.9 17.1 0.00026 21.9 17.1 3.1 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal SH3_2 PF07653.17 PRP82026.1 - 0.025 14.3 0.2 19 5.0 0.0 4.0 3 1 1 4 4 4 0 Variant SH3 domain SH3_15 PF18346.1 PRP82026.1 - 0.25 11.7 2.1 26 5.2 0.1 3.7 3 1 0 3 3 3 0 Mind bomb SH3 repeat domain KN17_SH3 PF18131.1 PRP82026.1 - 7.4 6.8 9.8 6.2 7.0 0.2 4.2 4 0 0 4 4 4 0 KN17 SH3-like C-terminal domain Bap31_Bap29_C PF18035.1 PRP82028.1 - 0.0071 16.3 0.3 0.024 14.6 0.1 2.0 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain SidE PF12252.8 PRP82028.1 - 0.073 10.6 0.2 0.11 10.1 0.2 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein MutS_V PF00488.21 PRP82029.1 - 1.4e-48 165.5 0.1 4.1e-48 163.9 0.1 1.8 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PRP82029.1 - 1.4e-26 93.9 0.4 5.5e-26 92.0 0.1 2.2 2 0 0 2 2 2 1 MutS domain III BTB_2 PF02214.22 PRP82030.1 - 1e-23 83.5 0.0 4.1e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 PRP82030.1 - 4.8e-12 45.9 0.0 1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Glycos_transf_1 PF00534.20 PRP82031.1 - 6.1e-10 38.9 0.0 1.5e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PRP82031.1 - 9.9e-07 29.3 0.0 2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PRP82031.1 - 0.079 13.4 0.0 0.75 10.2 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 SET PF00856.28 PRP82032.1 - 7.9e-10 39.4 0.0 3e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 SET domain DRMBL PF07522.14 PRP82033.1 - 6.1e-30 103.6 0.0 1.4e-29 102.5 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 PRP82033.1 - 0.0006 19.7 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 PRP82033.1 - 0.0072 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP82033.1 - 0.0078 16.2 0.1 0.02 14.9 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.22 PRP82034.1 - 2.9e-15 55.8 5.7 2.3e-06 27.3 0.1 4.9 3 2 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PRP82034.1 - 0.0014 18.5 0.0 0.29 11.0 0.0 2.8 3 0 0 3 3 3 2 Occluded RNA-recognition motif DUF5633 PF18656.1 PRP82034.1 - 1.5 8.7 6.1 16 5.5 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5633) HLH PF00010.26 PRP82035.1 - 1.1e-06 28.5 1.7 2.1e-06 27.6 1.3 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain NRBF2 PF08961.10 PRP82035.1 - 0.0015 18.2 0.8 0.0029 17.3 0.8 1.5 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 PRP82035.1 - 0.01 16.1 3.2 0.01 16.1 3.2 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-RING_2 PF13639.6 PRP82036.1 - 1.6e-15 57.1 15.8 1.4e-08 35.0 6.8 3.4 3 0 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 PRP82036.1 - 1.7e-12 47.1 17.8 5.2e-06 26.3 5.2 3.3 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.25 PRP82036.1 - 7.7e-09 35.3 16.3 2.9e-05 23.8 5.0 3.3 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP82036.1 - 1.5e-08 34.4 17.9 7.1e-05 22.6 4.7 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP82036.1 - 2e-08 34.0 19.4 0.00048 19.9 0.9 4.3 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 PRP82036.1 - 4.2e-08 33.4 15.7 0.00012 22.3 4.4 3.3 2 1 1 3 3 3 2 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PRP82036.1 - 1.1e-07 31.8 12.0 0.0025 17.8 4.1 3.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 PRP82036.1 - 4.2e-07 29.9 21.0 0.00016 21.6 1.0 4.9 4 1 0 4 4 4 2 RING-type zinc-finger zf-RING_11 PF17123.5 PRP82036.1 - 1.1e-06 28.2 6.7 0.00011 21.9 2.4 4.4 5 0 0 5 5 5 2 RING-like zinc finger IQ PF00612.27 PRP82036.1 - 3.5e-05 23.2 1.5 0.0001 21.7 1.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C3HC4_2 PF13923.6 PRP82036.1 - 3.6e-05 23.5 22.0 0.00099 18.9 6.7 3.9 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP82036.1 - 0.003 17.7 16.2 0.083 13.1 4.2 3.8 3 1 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 PRP82036.1 - 0.006 16.7 11.2 0.039 14.1 1.9 3.0 3 0 0 3 3 3 2 Zinc-binding RING-finger zf-HC5HC2H_2 PF13832.6 PRP82036.1 - 0.0077 16.4 2.8 0.0077 16.4 2.8 2.9 2 2 0 2 2 2 1 PHD-zinc-finger like domain zf-Di19 PF05605.12 PRP82036.1 - 0.022 15.1 10.4 13 6.1 0.1 4.3 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-HC5HC2H PF13771.6 PRP82036.1 - 0.027 14.7 3.3 0.027 14.7 3.3 3.5 2 2 0 3 3 3 0 PHD-like zinc-binding domain PHD PF00628.29 PRP82036.1 - 0.87 9.5 13.4 10 6.1 4.6 3.5 2 1 1 3 3 3 0 PHD-finger DUF5318 PF17249.2 PRP82036.1 - 1.6 8.5 9.5 4 7.2 0.3 3.8 3 1 1 4 4 4 0 Family of unknown function (DUF5318) Zn_ribbon_17 PF17120.5 PRP82036.1 - 1.8 8.3 11.1 0.92 9.2 0.8 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Zn-C2H2_12 PF18112.1 PRP82036.1 - 7.9 7.0 18.3 2.6 8.6 0.2 4.4 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain 3HCDH_N PF02737.18 PRP82040.1 - 3.8e-62 209.3 2.5 4.8e-62 209.0 2.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 PRP82040.1 - 5.9e-34 116.6 0.0 1.3e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 PRP82040.1 - 2.5e-07 30.8 0.1 3.6e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 PRP82040.1 - 9.6e-07 29.1 1.6 2e-06 28.0 1.6 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 PRP82040.1 - 0.00052 19.4 1.1 0.0026 17.1 1.1 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 PRP82040.1 - 0.00053 20.5 1.4 0.0015 19.0 1.4 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 PRP82040.1 - 0.00059 19.5 0.2 0.00093 18.8 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 PRP82040.1 - 0.0012 19.1 0.1 0.0023 18.2 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 PRP82040.1 - 0.013 15.6 0.9 0.037 14.1 0.9 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 PRP82040.1 - 0.018 14.6 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 PRP82040.1 - 0.025 14.6 0.1 0.72 9.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase XdhC_C PF13478.6 PRP82040.1 - 0.034 14.7 0.0 0.099 13.2 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain ApbA PF02558.16 PRP82040.1 - 0.062 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ras PF00071.22 PRP82041.1 - 4.7e-36 123.8 0.4 3.6e-17 62.4 0.1 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 PRP82041.1 - 1.8e-17 63.7 0.1 4.6e-15 55.9 0.1 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP82041.1 - 3.4e-10 39.7 0.2 0.00011 21.7 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family PduV-EutP PF10662.9 PRP82041.1 - 0.00043 20.1 0.1 0.078 12.7 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 PRP82041.1 - 0.0012 19.2 0.0 0.0014 19.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 PRP82041.1 - 0.0058 16.6 0.0 0.24 11.3 0.0 2.2 2 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 PRP82041.1 - 0.0062 15.9 0.0 0.01 15.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP82041.1 - 0.01 15.9 0.0 0.014 15.5 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 PRP82041.1 - 0.022 14.1 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 PRP82041.1 - 0.026 13.7 0.0 1.9 7.5 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 PRP82041.1 - 0.099 12.9 0.0 0.18 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PRP82041.1 - 0.1 12.3 0.1 0.41 10.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 PRP82041.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Arrestin_N PF00339.29 PRP82042.1 - 3e-05 24.1 1.2 0.00045 20.3 0.7 2.7 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PRP82042.1 - 0.048 14.1 2.0 0.45 11.0 0.0 3.0 3 1 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain DUF2939 PF11159.8 PRP82043.1 - 1.3 9.4 3.6 2 8.9 0.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2939) ubiquitin PF00240.23 PRP82044.1 - 9.2e-09 34.9 0.7 2.4e-08 33.6 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 PRP82044.1 - 1.3e-05 25.6 0.2 5.7e-05 23.5 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 PRP82044.1 - 0.00026 20.7 0.4 0.0012 18.6 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 PRP82044.1 - 0.0084 16.1 0.5 0.076 13.1 0.4 1.9 1 1 1 2 2 2 1 Ubiquitin-like domain TRAPPC10 PF12584.8 PRP82046.1 - 3e-09 36.8 0.0 6.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 PRP82046.1 - 0.045 13.3 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Foie gras liver health family 1 Gryzun-like PF12742.7 PRP82046.1 - 0.092 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Glu-tRNAGln PF02686.15 PRP82047.1 - 1.5e-09 38.0 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit PIG-S PF10510.9 PRP82047.1 - 0.045 12.6 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Sec15 PF04091.12 PRP82047.1 - 0.061 12.7 0.0 0.078 12.4 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like CLU PF13236.6 PRP82048.1 - 3.8e-57 193.7 0.0 1e-56 192.3 0.0 1.8 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP82048.1 - 3.9e-08 33.5 0.2 1.7e-07 31.4 0.2 2.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 zf-UBR PF02207.20 PRP82048.1 - 5.4e-07 29.7 14.6 1.3e-06 28.5 14.6 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) LRR_4 PF12799.7 PRP82048.1 - 8.9e-06 26.0 15.1 0.051 14.0 0.1 7.1 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP82048.1 - 9.1e-06 25.3 10.4 0.29 11.3 0.0 7.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 PRP82048.1 - 0.012 15.3 7.5 6.2 6.7 0.0 5.9 5 1 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 PRP82048.1 - 1.3 9.9 14.2 8.5 7.4 0.0 7.8 7 1 0 7 7 7 0 Leucine Rich Repeat Ras PF00071.22 PRP82049.1 - 9.3e-52 174.9 0.0 1.3e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Ras family BTB PF00651.31 PRP82049.1 - 4.6e-34 117.0 0.0 2.8e-19 69.4 0.0 3.4 2 2 1 3 3 3 2 BTB/POZ domain Roc PF08477.13 PRP82049.1 - 1.7e-23 83.1 0.0 3.4e-23 82.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP82049.1 - 2.5e-10 40.1 0.0 4.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family BACK PF07707.15 PRP82049.1 - 0.0002 21.4 0.2 0.0033 17.5 0.1 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch GTP_EFTU PF00009.27 PRP82049.1 - 0.0073 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Pkinase_Tyr PF07714.17 PRP82050.1 - 2.6e-53 181.0 0.0 4.8e-51 173.5 0.0 3.1 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP82050.1 - 3.4e-48 161.2 79.5 8.1e-09 35.1 4.2 13.5 12 1 1 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 PRP82050.1 - 9.8e-41 137.1 84.4 1.2e-05 25.6 3.6 17.3 10 3 8 18 18 18 14 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP82050.1 - 8.8e-33 113.8 0.1 1.7e-31 109.6 0.1 2.6 1 1 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 PRP82050.1 - 9.5e-11 40.9 67.3 0.3 11.2 0.5 19.4 22 0 0 22 22 21 6 Leucine Rich repeat LRR_1 PF00560.33 PRP82050.1 - 3.1e-07 30.0 56.6 0.32 11.7 0.0 20.1 23 0 0 23 23 22 1 Leucine Rich Repeat Kdo PF06293.14 PRP82050.1 - 7.1e-05 22.2 0.3 0.00012 21.5 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP82050.1 - 0.0022 16.9 0.1 0.0033 16.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP82050.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Amnionless PF14828.6 PRP82050.1 - 0.13 11.1 0.2 0.2 10.4 0.2 1.2 1 0 0 1 1 1 0 Amnionless LRR_9 PF14580.6 PRP82050.1 - 0.36 10.3 5.2 0.72 9.3 0.1 3.9 5 0 0 5 5 5 0 Leucine-rich repeat Insulin_TMD PF17870.1 PRP82050.1 - 1.2 9.3 3.7 2.6 8.2 3.7 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pkinase_Tyr PF07714.17 PRP82051.1 - 3.2e-61 206.9 0.0 1.9e-59 201.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP82051.1 - 3.8e-48 161.1 80.0 8.1e-09 35.1 4.2 13.3 12 1 1 13 13 13 11 Leucine rich repeat Pkinase PF00069.25 PRP82051.1 - 1.7e-42 145.6 0.0 9.8e-42 143.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP82051.1 - 2.6e-41 138.9 84.2 2.3e-05 24.7 3.5 17.0 11 4 5 17 17 17 14 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP82051.1 - 9.2e-13 47.1 59.8 0.3 11.3 0.3 19.9 21 0 0 21 21 21 5 Leucine Rich repeat LRR_1 PF00560.33 PRP82051.1 - 2.3e-07 30.4 56.8 0.43 11.3 0.0 20.7 22 1 0 22 22 22 1 Leucine Rich Repeat Kdo PF06293.14 PRP82051.1 - 7.2e-05 22.2 0.3 0.00012 21.5 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP82051.1 - 0.0012 17.7 0.2 0.0021 16.9 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP82051.1 - 0.0086 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Amnionless PF14828.6 PRP82051.1 - 0.01 14.7 0.2 0.021 13.7 0.2 1.4 1 0 0 1 1 1 0 Amnionless DUF1921 PF09081.10 PRP82051.1 - 0.079 13.2 0.6 0.26 11.5 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) LRRNT_2 PF08263.12 PRP82051.1 - 0.08 13.3 1.1 0.29 11.5 1.1 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain VSP PF03302.13 PRP82051.1 - 0.51 9.1 1.4 0.85 8.4 1.4 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein LRR_9 PF14580.6 PRP82051.1 - 1.9 8.0 7.8 0.72 9.3 0.2 4.0 4 0 0 4 4 4 0 Leucine-rich repeat PTR2 PF00854.21 PRP82052.1 - 7e-54 183.2 4.8 1.5e-53 182.0 4.8 1.5 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 PRP82052.1 - 1.6e-10 40.5 28.2 1.6e-10 40.5 28.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_3 PF16083.5 PRP82052.1 - 0.015 15.4 3.2 0.098 12.8 3.2 2.5 1 1 0 1 1 1 0 LydA holin phage, holin superfamily III DUF4173 PF13777.6 PRP82052.1 - 0.2 11.1 22.3 0.039 13.4 4.9 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4173) Sacchrp_dh_NADP PF03435.18 PRP82053.1 - 2.2e-14 53.8 0.1 3.7e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 PRP82053.1 - 0.0031 17.0 0.0 0.0049 16.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 PRP82053.1 - 0.0042 17.0 0.0 0.007 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 PRP82053.1 - 0.082 12.2 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 PRP82053.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2798 PF11391.8 PRP82053.1 - 0.12 12.4 2.0 1.4 9.0 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) HEAT PF02985.22 PRP82055.1 - 1.9e-22 77.4 1.8 0.0032 17.6 0.0 9.2 9 0 0 9 9 9 4 HEAT repeat CLASP_N PF12348.8 PRP82055.1 - 1.2e-18 67.5 2.3 6.9e-10 38.9 0.0 3.6 3 1 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 PRP82055.1 - 3.4e-12 46.6 0.0 0.0073 16.8 0.0 5.4 4 0 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 PRP82055.1 - 4.3e-11 43.1 0.0 0.12 12.7 0.0 7.2 5 1 1 7 7 7 2 HEAT repeats Cnd1 PF12717.7 PRP82055.1 - 3.7e-08 33.6 7.5 0.18 11.8 0.1 6.0 5 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PRP82055.1 - 1.1e-07 32.3 0.4 2.7 8.7 0.0 6.0 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 PRP82055.1 - 5.6e-05 22.4 0.7 0.0037 16.4 0.1 3.1 2 0 0 2 2 2 1 Dopey, N-terminal IFRD PF05004.13 PRP82055.1 - 0.00019 20.6 0.1 0.15 11.2 0.0 4.4 6 0 0 6 6 6 1 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 PRP82055.1 - 0.00025 19.7 3.8 0.87 8.1 0.0 4.2 3 1 0 3 3 3 2 Adaptin N terminal region Tti2 PF10521.9 PRP82055.1 - 0.00038 20.1 0.1 0.13 11.8 0.0 4.2 4 0 0 4 4 4 1 Tti2 family RasGEF_N_2 PF14663.6 PRP82055.1 - 0.02 15.3 0.5 2 8.9 0.1 3.4 3 0 0 3 3 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain NUC173 PF08161.12 PRP82055.1 - 0.025 14.2 1.0 2.3 7.8 0.0 3.9 3 1 0 4 4 4 0 NUC173 domain ENTH PF01417.20 PRP82055.1 - 0.031 14.3 1.2 7.1 6.7 0.0 4.2 4 0 0 4 4 4 0 ENTH domain Tht1 PF04163.12 PRP82055.1 - 0.072 11.8 0.4 0.12 11.1 0.4 1.2 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein MMS19_C PF12460.8 PRP82055.1 - 0.1 11.7 1.6 51 2.8 0.0 4.1 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal ParcG PF10274.9 PRP82055.1 - 0.21 11.7 1.4 1.5 8.9 0.2 2.8 3 0 0 3 3 3 0 Parkin co-regulated protein RRM_1 PF00076.22 PRP82056.1 - 1.2e-87 287.7 4.2 4.4e-21 74.5 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox_KN PF05920.11 PRP82056.1 - 7.3e-17 61.0 0.1 1.9e-16 59.7 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain PABP PF00658.18 PRP82056.1 - 1.7e-15 56.9 1.2 4e-15 55.7 0.5 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 PRP82056.1 - 4.2e-11 42.5 0.1 0.091 12.4 0.0 4.3 1 1 2 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 PRP82056.1 - 1e-09 38.3 0.8 0.01 15.9 0.0 4.7 4 0 0 4 4 4 2 Limkain b1 Homeodomain PF00046.29 PRP82056.1 - 1.5e-05 24.8 2.9 2.8e-05 23.8 0.9 2.6 2 1 0 2 2 2 1 Homeodomain RRM_7 PF16367.5 PRP82056.1 - 2.3e-05 24.4 0.1 0.91 9.7 0.0 4.7 4 0 0 4 4 4 1 RNA recognition motif YflT PF11181.8 PRP82056.1 - 0.00011 22.7 2.6 0.16 12.5 0.0 3.5 3 0 0 3 3 3 2 Heat induced stress protein YflT RRM_occluded PF16842.5 PRP82056.1 - 0.0007 19.4 0.0 14 5.7 0.0 4.4 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PRP82056.1 - 0.0019 18.1 0.2 9.9 6.3 0.0 3.9 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PRP82056.1 - 0.0035 17.4 6.7 2.5 8.2 1.2 4.5 2 1 2 4 4 4 1 RNA binding motif DNA_ligase_IV PF11411.8 PRP82056.1 - 0.081 13.1 0.2 13 6.0 0.0 3.3 3 0 0 3 3 3 0 DNA ligase IV PEN-2 PF10251.9 PRP82057.1 - 1.9e-25 89.1 2.5 2.2e-25 88.9 2.5 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase CCSAP PF15748.5 PRP82058.1 - 0.056 13.6 16.9 0.071 13.3 16.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 PRP82058.1 - 1.2 7.9 13.8 1.2 7.8 13.8 1.1 1 0 0 1 1 1 0 Presenilin Mucin PF01456.17 PRP82058.1 - 2.1 8.3 10.6 4.1 7.4 10.6 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Apt1 PF10351.9 PRP82058.1 - 3.1 6.5 16.6 4.1 6.1 16.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 PRP82058.1 - 3.6 6.0 12.4 4.3 5.8 12.4 1.2 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 PRP82058.1 - 7.6 4.7 12.9 8.1 4.6 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Catalase PF00199.19 PRP82059.1 - 6e-178 591.8 0.1 7.7e-178 591.4 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 PRP82059.1 - 4.2e-18 65.4 0.1 7.6e-18 64.6 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 PRP82059.1 - 2e-17 63.2 0.0 4e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 PRP82059.1 - 1.4e-07 31.5 0.1 2.6e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DUF5071 PF16804.5 PRP82060.1 - 5.2e-08 33.2 0.2 6.6e-08 32.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5071) Pkinase_Tyr PF07714.17 PRP82062.1 - 2.4e-39 135.2 0.2 3.2e-39 134.8 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82062.1 - 2.1e-31 109.2 0.1 3.2e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP82062.1 - 2.2e-10 40.9 4.0 6e-10 39.5 4.0 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Chlam_PMP PF02415.17 PRP82062.1 - 1.3e-09 37.9 141.9 0.12 12.9 1.0 21.8 22 0 0 22 22 22 9 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kinase-like PF14531.6 PRP82062.1 - 0.00096 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Insulin_TMD PF17870.1 PRP82062.1 - 0.0053 16.8 1.4 0.016 15.2 1.4 1.8 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 PRP82062.1 - 0.075 13.9 0.3 0.18 12.7 0.3 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 PRP82062.1 - 0.078 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Amnionless DUF3827 PF12877.7 PRP82062.1 - 0.11 10.8 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TMEM154 PF15102.6 PRP82062.1 - 0.13 12.2 1.2 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family Pkinase_Tyr PF07714.17 PRP82064.1 - 2.1e-32 112.5 0.1 2.8e-32 112.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82064.1 - 2e-27 96.2 0.0 3.5e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP82064.1 - 9.9e-11 42.0 5.8 4.3e-10 40.0 5.3 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP82064.1 - 0.00025 20.5 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4957 PF16318.5 PRP82064.1 - 0.45 10.4 13.8 0.35 10.8 1.8 4.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4957) Chlam_PMP PF02415.17 PRP82064.1 - 0.45 11.1 85.1 0.3 11.6 0.5 14.3 15 0 0 15 15 15 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat HALZ PF02183.18 PRP82066.1 - 0.0041 17.3 5.7 0.0041 17.3 5.7 20.8 22 3 2 24 24 24 3 Homeobox associated leucine zipper Fungal_TACC PF12709.7 PRP82066.1 - 0.0047 17.3 5.0 0.0047 17.3 5.0 23.1 14 7 10 26 26 26 3 Fungal Transforming acidic coiled-coil (TACC) proteins ZapB PF06005.12 PRP82066.1 - 0.036 14.5 0.3 0.036 14.5 0.3 24.5 13 8 3 17 17 17 0 Cell division protein ZapB AKAP7_NLS PF10469.9 PRP82067.1 - 7.2e-26 91.4 0.1 2.3e-25 89.7 0.0 1.9 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 PRP82067.1 - 6e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 PRP82067.1 - 0.014 15.5 0.0 6.6 7.0 0.0 2.7 2 0 0 2 2 2 0 LigT like Phosphoesterase Pkinase_Tyr PF07714.17 PRP82068.1 - 2.3e-52 177.9 0.0 3.3e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82068.1 - 1.7e-31 109.6 0.0 3.5e-31 108.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 PRP82068.1 - 2.9e-19 68.6 4.2 9e-06 25.4 0.0 5.0 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 PRP82068.1 - 4.6e-13 49.1 12.9 0.11 13.0 0.1 7.1 4 2 3 8 8 8 5 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP82068.1 - 6.2e-05 22.4 0.0 9.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP82068.1 - 0.00075 18.9 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP82068.1 - 0.0012 17.8 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase LRRNT_2 PF08263.12 PRP82068.1 - 0.0035 17.6 0.2 0.009 16.3 0.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PRP82068.1 - 0.038 14.5 8.9 7.3 7.6 0.1 6.9 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 PRP82068.1 - 0.24 11.5 4.6 90 3.5 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Pkinase_Tyr PF07714.17 PRP82071.1 - 3.9e-70 236.1 0.0 5.8e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82071.1 - 7e-49 166.6 0.0 1e-48 166.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP82071.1 - 1.1e-47 159.6 80.1 6.1e-08 32.3 0.0 13.8 11 3 3 15 15 15 14 Leucine rich repeat LRR_4 PF12799.7 PRP82071.1 - 3.2e-37 125.9 82.2 2.9e-05 24.3 6.1 17.8 8 4 10 20 20 20 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP82071.1 - 7.9e-09 34.9 60.6 0.82 10.5 0.0 19.8 21 3 0 21 21 19 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP82071.1 - 2.7e-06 27.0 60.7 0.69 10.1 0.1 17.6 20 0 0 20 20 19 3 Leucine Rich repeat Kdo PF06293.14 PRP82071.1 - 0.0003 20.2 0.1 0.00051 19.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP82071.1 - 0.00041 19.8 0.0 0.00072 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP82071.1 - 0.0022 16.8 0.0 0.0037 16.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Amnionless PF14828.6 PRP82071.1 - 0.009 14.9 0.2 0.015 14.1 0.2 1.2 1 0 0 1 1 1 1 Amnionless LRRNT_2 PF08263.12 PRP82071.1 - 0.023 15.0 0.3 0.023 15.0 0.3 2.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain VSP PF03302.13 PRP82071.1 - 0.083 11.7 1.7 0.14 11.0 1.7 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Haspin_kinase PF12330.8 PRP82071.1 - 0.12 11.3 0.1 0.64 8.9 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain DUF4690 PF15756.5 PRP82071.1 - 0.17 12.5 0.3 0.56 10.8 0.3 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF347 PF03988.12 PRP82071.1 - 0.21 11.8 1.4 0.83 9.9 1.4 2.1 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DNA_pol_phi PF04931.13 PRP82075.1 - 0.22 9.6 9.3 0.27 9.3 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi RGS PF00615.19 PRP82076.1 - 2.5e-18 66.5 0.6 5.5e-18 65.3 0.6 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain SH2 PF00017.24 PRP82076.1 - 5e-15 55.4 0.1 2.3e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP82076.1 - 0.0037 18.0 0.1 0.01 16.5 0.1 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain PRANC PF09372.10 PRP82076.1 - 0.0099 16.2 1.6 5.5 7.4 0.0 3.4 3 0 0 3 3 3 2 PRANC domain MitMem_reg PF13012.6 PRP82078.1 - 0.49 10.8 6.8 1.5 9.3 0.7 2.6 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Peptidase_M75 PF09375.10 PRP82078.1 - 0.69 9.3 6.3 0.48 9.8 1.7 2.1 2 0 0 2 2 2 0 Imelysin DUF4439 PF14530.6 PRP82078.1 - 0.7 10.6 2.9 0.56 10.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4439) Lipase_3 PF01764.25 PRP82079.1 - 6.4e-22 78.0 0.0 1.2e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) fn3 PF00041.21 PRP82079.1 - 2.1e-10 40.8 2.3 2.5e-10 40.6 0.9 1.9 2 0 0 2 2 2 1 Fibronectin type III domain Hydrolase_4 PF12146.8 PRP82079.1 - 4.4e-05 22.9 0.0 0.00012 21.4 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PRP82079.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 PRP82079.1 - 0.076 13.6 0.0 0.2 12.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Exo_endo_phos PF03372.23 PRP82080.1 - 8.3e-09 35.3 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ECH_1 PF00378.20 PRP82081.1 - 1.1e-35 123.2 0.0 1.2e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP82081.1 - 3.1e-16 59.8 0.0 3.8e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ank_2 PF12796.7 PRP82082.1 - 0.067 13.8 0.0 3.2 8.4 0.0 2.1 1 1 0 2 2 2 0 Ankyrin repeats (3 copies) Nup54 PF13874.6 PRP82084.1 - 3.1e-31 108.3 1.7 3.1e-31 108.3 1.7 1.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF3847 PF12958.7 PRP82084.1 - 0.16 12.1 3.8 0.33 11.1 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) BLOC1_2 PF10046.9 PRP82084.1 - 0.33 11.3 2.3 18 5.7 0.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nucleoporin_FG PF13634.6 PRP82084.1 - 4.5 8.2 70.5 11 6.9 30.5 3.3 1 1 2 3 3 3 0 Nucleoporin FG repeat region DUF5600 PF18150.1 PRP82085.1 - 0.092 13.3 0.7 0.22 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5600) PI3_PI4_kinase PF00454.27 PRP82087.1 - 1.1e-53 182.7 0.1 2.5e-52 178.2 0.1 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PRP82087.1 - 2.1e-50 170.7 0.3 3.8e-50 169.9 0.3 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_rbd PF00794.18 PRP82087.1 - 1.4e-06 28.5 0.3 0.002 18.2 0.2 2.9 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 PRP82087.1 - 0.0008 18.8 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) PI3K_C2 PF00792.24 PRP82087.1 - 0.0012 18.7 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Pkinase_Tyr PF07714.17 PRP82088.1 - 7.6e-69 231.9 0.0 1.3e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82088.1 - 4.6e-51 173.7 0.0 9.6e-51 172.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain BcrAD_BadFG PF01869.20 PRP82088.1 - 4.7e-34 118.1 0.3 1.4e-33 116.6 0.1 1.8 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family dCache_1 PF02743.18 PRP82088.1 - 2.2e-05 24.4 0.1 4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Cache domain Kdo PF06293.14 PRP82088.1 - 0.00019 20.8 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP82088.1 - 0.008 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP82088.1 - 0.0094 14.9 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 PRP82088.1 - 0.055 12.8 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like OppC_N PF12911.7 PRP82088.1 - 0.7 9.9 3.3 9.6 6.3 0.3 3.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Sigma_reg_N PF13800.6 PRP82088.1 - 0.85 9.9 3.7 1.1 9.5 1.0 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Glyco_hydro_18 PF00704.28 PRP82089.1 - 6.7e-28 98.3 4.6 1.1e-27 97.6 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SAPS PF04499.15 PRP82089.1 - 0.053 12.3 2.7 0.08 11.7 2.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CLN3 PF02487.17 PRP82089.1 - 0.41 9.6 5.3 0.75 8.8 5.3 1.4 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 PRP82089.1 - 3 6.5 9.7 4.7 5.9 9.7 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 PRP82089.1 - 3.1 6.5 13.2 4.7 5.9 13.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain VPS9 PF02204.18 PRP82090.1 - 8.1e-07 29.2 0.0 2.2e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SH2 PF00017.24 PRP82090.1 - 4.6e-05 23.4 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 SH2 domain TPR_1 PF00515.28 PRP82090.1 - 0.0035 17.1 1.4 0.0065 16.3 1.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82090.1 - 0.014 15.5 0.9 0.031 14.4 0.9 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HBS1_N PF08938.10 PRP82090.1 - 0.015 15.6 0.0 0.052 13.8 0.0 1.9 2 0 0 2 2 2 0 HBS1 N-terminus STAT_int PF02865.17 PRP82090.1 - 0.1 13.1 0.3 0.35 11.4 0.3 1.9 1 0 0 1 1 1 0 STAT protein, protein interaction domain ERp29 PF07749.12 PRP82090.1 - 0.14 13.1 0.2 1.7 9.6 0.0 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain TPR_14 PF13428.6 PRP82090.1 - 0.14 13.1 0.1 0.92 10.5 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat PPR_3 PF13812.6 PRP82092.1 - 1.8e-17 63.2 1.3 6.8e-05 22.9 0.0 2.8 1 1 3 4 4 4 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 PRP82092.1 - 1.6e-15 57.0 0.6 5.2e-07 29.8 0.2 3.6 1 1 1 3 3 3 3 PPR repeat family PPR_long PF17177.4 PRP82092.1 - 1.1e-06 28.2 0.1 8.5e-05 22.0 0.1 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PRP82092.1 - 3.1e-05 23.9 0.2 0.13 12.6 0.0 4.7 5 0 0 5 5 5 1 PPR repeat Exog_C PF18026.1 PRP82092.1 - 0.00035 20.6 0.1 0.64 10.1 0.0 3.2 3 0 0 3 3 3 2 Endo/exonuclease (EXOG) C-terminal domain PTH2 PF01981.16 PRP82092.1 - 0.029 14.7 0.5 0.16 12.2 0.5 2.2 1 1 1 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 PPR_1 PF12854.7 PRP82092.1 - 0.032 14.0 0.0 0.96 9.2 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Pkinase_Tyr PF07714.17 PRP82093.1 - 4.9e-82 275.1 0.0 7.1e-82 274.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82093.1 - 1e-49 169.3 0.0 1.6e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP82093.1 - 3e-45 151.8 69.3 2.2e-09 36.9 5.1 11.5 5 2 7 13 13 13 12 Leucine rich repeat LRR_4 PF12799.7 PRP82093.1 - 1.5e-41 139.7 60.3 2e-06 28.0 0.9 13.3 9 2 4 14 14 14 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP82093.1 - 5.1e-21 72.0 59.6 0.067 13.8 0.3 20.9 23 0 0 23 23 22 6 Leucine Rich Repeat LRR_6 PF13516.6 PRP82093.1 - 5.9e-18 63.3 76.0 0.054 13.6 0.1 20.7 22 0 0 22 22 22 9 Leucine Rich repeat LRR_9 PF14580.6 PRP82093.1 - 0.006 16.1 13.0 0.51 9.8 0.2 5.1 2 1 3 6 6 6 3 Leucine-rich repeat Haspin_kinase PF12330.8 PRP82093.1 - 0.0064 15.5 0.2 0.022 13.7 0.2 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PRP82093.1 - 0.029 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 PRP82093.1 - 0.031 14.2 0.0 0.14 12.1 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family LRRNT_2 PF08263.12 PRP82093.1 - 0.067 13.5 0.8 0.27 11.5 0.8 2.1 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain NAD_binding_6 PF08030.12 PRP82094.1 - 2.3e-20 73.3 0.0 2.9e-17 63.2 0.0 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 PRP82094.1 - 2e-18 66.7 8.5 2e-18 66.7 8.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 PRP82094.1 - 2.7e-15 56.4 0.0 6.9e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 PRP82094.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Ras PF00071.22 PRP82097.1 - 2.5e-48 163.7 0.0 6.6e-48 162.4 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP82097.1 - 2e-22 79.7 0.0 5.2e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ubiquitin PF00240.23 PRP82097.1 - 2.7e-12 46.3 0.0 8.1e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Arf PF00025.21 PRP82097.1 - 5.5e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Rad60-SLD PF11976.8 PRP82097.1 - 0.00015 21.5 0.0 0.00049 19.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PRP82097.1 - 0.02 15.3 1.0 0.038 14.4 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 PRP82097.1 - 0.037 14.6 1.0 2.6 8.7 0.0 3.0 2 1 0 3 3 3 0 DUF2407 ubiquitin-like domain USP7_ICP0_bdg PF12436.8 PRP82097.1 - 0.15 11.3 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 HEAT_2 PF13646.6 PRP82098.1 - 7.5e-18 64.7 6.9 1.6e-07 31.6 0.1 5.2 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 PRP82098.1 - 7.6e-18 63.1 8.5 0.0019 18.3 0.1 7.1 6 0 0 6 6 6 6 HEAT repeat Cnd1 PF12717.7 PRP82098.1 - 3.1e-11 43.6 18.5 0.0031 17.6 0.0 5.6 4 2 1 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PRP82098.1 - 3.5e-07 30.6 4.9 0.29 11.7 0.0 5.4 5 0 0 5 5 5 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 PRP82098.1 - 3.2e-05 24.4 2.7 0.37 11.4 0.1 5.0 3 2 3 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 PRP82098.1 - 0.00032 20.3 7.8 0.039 13.5 0.3 3.9 4 0 0 4 4 4 2 CLASP N terminal RTP1_C1 PF10363.9 PRP82098.1 - 0.0018 18.4 2.9 2.9 8.1 0.0 5.1 4 2 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 PRP82098.1 - 0.009 15.2 5.5 0.14 11.3 0.1 4.0 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain LisH_TPL PF17814.1 PRP82098.1 - 0.31 10.7 2.3 8.5 6.1 0.3 3.3 3 0 0 3 3 3 0 LisH-like dimerisation domain Arm PF00514.23 PRP82098.1 - 0.52 10.4 3.3 8.5 6.6 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 PRP82098.1 - 2.2 8.7 9.4 79 3.7 0.1 5.3 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion UBZ_FAAP20 PF15750.5 PRP82099.1 - 0.044 13.7 0.6 0.097 12.6 0.6 1.6 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger RNF220 PF15926.5 PRP82099.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 DUF2866 PF11065.8 PRP82099.1 - 0.12 12.4 0.1 0.35 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) Pkinase PF00069.25 PRP82100.1 - 3.1e-30 105.4 0.0 4.1e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82100.1 - 6.5e-17 61.7 0.0 8.8e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP82100.1 - 0.001 17.9 0.1 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP82100.1 - 0.012 15.0 0.0 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 PRP82100.1 - 0.02 15.1 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 PRP82100.1 - 0.13 12.1 0.0 0.73 9.7 0.0 2.2 3 1 1 4 4 4 0 Phosphotransferase enzyme family NosD PF05048.13 PRP82101.1 - 0.14 11.4 13.4 0.1 11.8 1.9 2.5 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Ephrin_rec_like PF07699.13 PRP82101.1 - 0.51 10.2 5.0 0.59 10.0 0.7 2.8 2 0 0 2 2 2 0 Putative ephrin-receptor like TBCC PF07986.12 PRP82101.1 - 1.6 8.5 5.8 0.82 9.4 2.7 2.2 3 0 0 3 3 3 0 Tubulin binding cofactor C WD40 PF00400.32 PRP82102.1 - 1.5e-56 187.0 27.1 2.5e-07 31.3 0.5 12.7 13 0 0 13 13 13 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82102.1 - 4.5e-25 87.8 2.1 1.6e-05 25.1 0.0 8.9 3 2 6 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 PRP82102.1 - 1.4e-13 51.1 0.7 2.8e-13 50.1 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 PRP82102.1 - 3.3e-13 49.3 7.2 0.016 14.2 0.1 7.8 3 2 4 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PRP82102.1 - 6.3e-09 35.6 6.6 0.0056 16.1 0.1 3.7 3 1 0 3 3 3 3 WD40-like domain Nup160 PF11715.8 PRP82102.1 - 4.2e-06 25.7 5.3 0.0098 14.6 0.1 3.8 4 1 0 4 4 4 2 Nucleoporin Nup120/160 HPS3_N PF14761.6 PRP82102.1 - 0.00011 21.9 0.5 5 6.6 0.0 4.2 3 1 1 4 4 4 2 Hermansky-Pudlak syndrome 3 Nucleoporin_N PF08801.11 PRP82102.1 - 0.00014 20.7 7.8 1.7 7.3 0.7 5.3 2 2 2 5 5 5 2 Nup133 N terminal like UTP15_C PF09384.10 PRP82102.1 - 0.00038 20.1 0.2 0.00038 20.1 0.2 1.8 2 0 0 2 2 2 1 UTP15 C terminal eIF2A PF08662.11 PRP82102.1 - 0.0059 16.5 2.5 4 7.3 0.0 4.4 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A AAA_23 PF13476.6 PRP82102.1 - 0.11 13.0 5.9 0.21 12.1 0.2 2.6 2 0 0 2 2 2 0 AAA domain Utp13 PF08625.11 PRP82102.1 - 0.11 12.4 1.8 0.12 12.3 0.3 1.9 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain Rhomboid PF01694.22 PRP82108.1 - 8.1e-37 126.5 15.4 8.1e-37 126.5 15.4 1.7 3 0 0 3 3 3 1 Rhomboid family DUF1751 PF08551.10 PRP82108.1 - 0.15 12.7 0.1 0.15 12.7 0.1 3.0 4 0 0 4 4 4 0 Eukaryotic integral membrane protein (DUF1751) DUF1761 PF08570.10 PRP82108.1 - 2.2 8.6 8.0 0.22 11.8 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) YwiC PF14256.6 PRP82108.1 - 9.4 6.6 9.3 5 7.4 6.0 2.0 1 1 1 2 2 2 0 YwiC-like protein Alpha-amylase PF00128.24 PRP82109.1 - 2.5e-15 56.9 0.4 1.8e-10 41.0 0.0 3.5 3 0 0 3 3 3 3 Alpha amylase, catalytic domain DUF4164 PF13747.6 PRP82109.1 - 0.036 14.3 1.6 0.13 12.5 1.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) TPH PF13868.6 PRP82109.1 - 0.046 12.2 5.4 0.071 11.6 5.4 1.2 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain ACAS_N PF16177.5 PRP82109.1 - 0.25 11.3 1.1 0.54 10.2 0.1 2.2 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus RhoGEF PF00621.20 PRP82109.1 - 4.3 7.5 6.5 1.8 8.8 1.9 2.6 3 0 0 3 3 3 0 RhoGEF domain Ank_2 PF12796.7 PRP82110.1 - 0.00046 20.7 0.0 0.015 15.9 0.0 3.3 4 1 1 5 5 5 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82110.1 - 0.001 19.6 0.0 1.9 9.2 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82110.1 - 0.015 15.8 0.0 9.9 7.1 0.0 4.8 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 PRP82110.1 - 0.044 14.1 0.0 10 6.6 0.0 3.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) PI3K_1B_p101 PF10486.9 PRP82111.1 - 1.2 6.8 7.1 1.5 6.5 7.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PGA2 PF07543.12 PRP82111.1 - 1.9 8.5 8.7 4.3 7.3 8.7 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 WRNPLPNID PF15017.6 PRP82111.1 - 8.7 7.3 10.7 9.9 7.1 8.5 2.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box DNA_pol_A_exo1 PF01612.20 PRP82112.1 - 8e-16 58.2 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease CRAL_TRIO PF00650.20 PRP82114.1 - 1.3e-37 129.0 0.0 1.8e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PRP82114.1 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP82114.1 - 0.00044 20.4 0.0 0.00085 19.5 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain EMG1 PF03587.14 PRP82115.1 - 9.3e-75 250.6 0.0 1.3e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ras PF00071.22 PRP82116.1 - 2.4e-44 150.8 1.2 3.8e-44 150.2 1.2 1.3 1 0 0 1 1 1 1 Ras family SH3_1 PF00018.28 PRP82116.1 - 2.5e-19 68.6 0.7 4.3e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 PRP82116.1 - 2.1e-15 56.3 0.4 1.7e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Roc PF08477.13 PRP82116.1 - 3.3e-15 56.4 0.2 7.8e-15 55.2 0.2 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SH3_2 PF07653.17 PRP82116.1 - 2.9e-13 49.3 0.2 2.1e-06 27.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain Arf PF00025.21 PRP82116.1 - 1.5e-09 37.6 0.1 2.9e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP82116.1 - 0.0003 20.7 0.1 0.0048 16.8 0.0 2.7 2 1 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 PRP82116.1 - 0.0042 17.2 1.3 0.012 15.7 0.2 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 PRP82116.1 - 0.0069 16.4 1.1 0.013 15.5 0.1 1.9 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 PRP82116.1 - 0.0083 15.7 0.6 0.0083 15.7 0.6 2.5 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF1107 PF06526.12 PRP82116.1 - 0.073 13.0 2.9 52 3.8 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1107) MttA_Hcf106 PF02416.16 PRP82116.1 - 0.12 11.7 0.1 0.31 10.4 0.1 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family SlyX PF04102.12 PRP82116.1 - 0.69 10.6 11.4 6.8 7.4 0.9 3.6 3 0 0 3 3 3 0 SlyX PCI PF01399.27 PRP82117.1 - 8.9e-11 42.2 2.3 2.3e-10 40.9 0.3 2.7 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 PRP82117.1 - 5.3e-06 26.0 1.4 1e-05 25.1 1.4 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix TBPIP PF07106.13 PRP82117.1 - 0.076 13.0 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain zf-MIZ PF02891.20 PRP82118.1 - 8.9e-17 60.6 1.9 8.9e-17 60.6 1.9 2.1 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-MYND PF01753.18 PRP82118.1 - 5.7e-10 39.1 14.5 5.7e-10 39.1 14.5 2.4 2 0 0 2 2 2 1 MYND finger SAP PF02037.27 PRP82118.1 - 5.9e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 PRP82118.1 - 5.2e-06 26.2 2.8 8.2e-06 25.5 1.9 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C6H2 PF15801.5 PRP82118.1 - 0.13 12.6 12.3 0.18 12.1 6.0 2.7 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-4CXXC_R1 PF10497.9 PRP82118.1 - 1.5 9.1 12.4 11 6.4 0.3 2.7 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Ribosomal_L37ae PF01780.19 PRP82119.1 - 6.2e-42 141.6 10.0 7e-42 141.4 10.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 PRP82119.1 - 0.00089 19.2 2.0 0.0014 18.6 2.0 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain C1_2 PF03107.16 PRP82119.1 - 0.062 13.6 2.4 0.19 12.1 2.4 1.7 1 1 0 1 1 1 0 C1 domain zf-RING_13 PF17977.1 PRP82119.1 - 0.076 13.2 4.8 0.092 12.9 3.7 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain A2L_zn_ribbon PF08792.10 PRP82119.1 - 0.09 12.5 3.7 4.2 7.2 0.7 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF1451 PF07295.11 PRP82119.1 - 0.12 12.5 0.7 0.16 12.0 0.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-H2C2_2 PF13465.6 PRP82119.1 - 0.46 11.0 5.1 1 9.9 0.9 2.2 1 1 1 2 2 2 0 Zinc-finger double domain zf-HIT PF04438.16 PRP82120.1 - 1.1e-09 38.0 14.5 1.7e-09 37.4 14.5 1.3 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 PRP82120.1 - 0.0013 18.5 0.2 0.0022 17.7 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CEBP_ZZ PF16366.5 PRP82120.1 - 0.28 11.5 7.8 0.53 10.6 7.8 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-MYND PF01753.18 PRP82120.1 - 0.28 11.3 14.9 0.5 10.5 14.9 1.4 1 0 0 1 1 1 0 MYND finger DUF3209 PF11483.8 PRP82120.1 - 0.3 11.5 0.1 0.3 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) PolC_DP2 PF03833.13 PRP82120.1 - 0.41 8.5 9.5 0.56 8.0 9.5 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Dynamin_N PF00350.23 PRP82121.1 - 5.9e-35 120.8 0.0 1.5e-22 80.5 0.0 2.6 2 0 0 2 2 2 2 Dynamin family Dynamin_M PF01031.20 PRP82121.1 - 4.1e-12 45.9 1.3 1.1e-05 24.9 0.0 3.1 5 0 0 5 5 5 2 Dynamin central region MMR_HSR1 PF01926.23 PRP82121.1 - 8.7e-09 35.5 0.0 0.00097 19.2 0.0 3.3 2 1 0 2 2 2 2 50S ribosome-binding GTPase Glyco_hydro_25 PF01183.20 PRP82121.1 - 0.12 12.5 0.2 15 5.8 0.1 2.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 25 Acyl_transf_3 PF01757.22 PRP82122.1 - 1.4e-18 67.1 44.8 3.9e-18 65.6 44.8 1.8 1 1 0 1 1 1 1 Acyltransferase family zf-C2H2_2 PF12756.7 PRP82123.1 - 2.1e-14 53.6 1.4 3.8e-14 52.8 1.4 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 PRP82123.1 - 0.36 11.8 4.6 4.9 8.3 1.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CNOT11 PF10155.9 PRP82124.1 - 2e-41 141.1 3.4 5.3e-41 139.7 3.4 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 UQ_con PF00179.26 PRP82126.1 - 4.6e-14 52.3 0.0 4.8e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_16 PF13432.6 PRP82127.1 - 1.9e-13 50.8 12.0 0.00042 20.9 1.3 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP82127.1 - 2.3e-13 50.5 22.4 0.0034 17.9 2.2 6.9 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82127.1 - 3.9e-11 42.2 36.3 0.0018 18.2 1.4 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP82127.1 - 3.7e-05 23.9 4.5 3.7e-05 23.9 4.5 5.1 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PRP82127.1 - 4.6e-05 23.6 22.5 2.2 8.6 0.0 8.3 6 3 3 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP82127.1 - 6e-05 22.7 33.6 0.029 14.2 0.3 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PRP82127.1 - 0.00021 21.0 0.4 3.4 7.3 0.0 4.6 4 1 1 5 5 5 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_14 PF13428.6 PRP82127.1 - 0.00031 21.3 9.7 1.4 9.9 0.0 7.5 7 1 2 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP82127.1 - 0.0013 19.3 31.4 0.011 16.4 0.8 8.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP82127.1 - 0.032 14.3 15.3 2.6 8.3 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat DSPn PF14671.6 PRP82127.1 - 0.11 12.9 2.3 0.76 10.2 0.1 2.7 3 0 0 3 3 3 0 Dual specificity protein phosphatase, N-terminal half TPR_8 PF13181.6 PRP82127.1 - 0.13 12.6 29.8 0.67 10.3 0.3 8.3 9 0 0 9 9 9 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PRP82127.1 - 1.7 8.7 21.2 2 8.4 5.7 4.9 5 2 0 5 5 5 0 Putative TPR-like repeat SH3_2 PF07653.17 PRP82128.1 - 1.8e-13 49.9 0.0 6.5e-13 48.2 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PRP82128.1 - 8.5e-13 48.0 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP82128.1 - 5.4e-11 41.9 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Peroxin-13_N PF04088.13 PRP82128.1 - 0.0009 19.5 0.3 0.0015 18.9 0.3 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region EbsA PF17255.2 PRP82129.1 - 3.6 8.0 11.8 4.4 7.7 2.1 2.7 3 0 0 3 3 3 0 EbsA-like protein Pkinase_Tyr PF07714.17 PRP82130.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase WWE PF02825.20 PRP82131.1 - 3.9e-09 37.0 7.6 8.4e-09 35.9 1.7 2.9 3 0 0 3 3 3 1 WWE domain Linker_histone PF00538.19 PRP82131.1 - 8.2e-06 26.1 0.2 1.7e-05 25.1 0.2 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family Malate_DH PF12434.8 PRP82131.1 - 6.5 6.9 10.4 2.1 8.4 0.3 3.3 4 0 0 4 4 4 0 Malate dehydrogenase enzyme NYN PF01936.18 PRP82132.1 - 5.4e-08 33.4 0.0 1.2e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 NYN domain RRM_1 PF00076.22 PRP82132.1 - 0.00046 20.0 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP82132.1 - 0.0082 16.2 0.1 0.045 13.9 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif DUF5615 PF18480.1 PRP82132.1 - 0.081 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Ank_2 PF12796.7 PRP82133.1 - 4.9e-21 75.1 0.0 1.7e-08 34.9 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP82133.1 - 1.5e-13 49.5 2.4 0.043 14.4 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 PRP82133.1 - 1.9e-13 50.3 3.5 0.0015 18.8 0.0 6.2 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP82133.1 - 6.2e-12 45.4 10.6 0.013 15.9 0.1 6.9 5 2 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 PRP82133.1 - 5.4e-10 39.6 0.3 1.4 9.6 0.0 5.3 4 3 1 5 5 5 5 Ankyrin repeats (many copies) Response_reg PF00072.24 PRP82135.1 - 0.0032 17.6 0.0 0.0036 17.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF2520 PF10728.9 PRP82135.1 - 0.053 13.3 0.0 0.053 13.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) ELO PF01151.18 PRP82136.1 - 1.7e-62 211.2 19.3 2e-62 211.0 19.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UQ_con PF00179.26 PRP82137.1 - 3.8e-42 143.3 0.0 5.1e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PRP82137.1 - 0.00036 20.4 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PRP82137.1 - 0.00076 19.8 0.1 0.002 18.4 0.1 1.4 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.11 PRP82137.1 - 0.082 12.5 0.0 0.32 10.6 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Maf PF02545.14 PRP82138.1 - 1.6e-28 99.6 0.0 1.8e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein zf_C2H2_10 PF18414.1 PRP82138.1 - 0.1 12.2 0.2 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger NMD3 PF04981.13 PRP82139.1 - 4.1e-81 272.0 8.0 5.4e-81 271.6 8.0 1.1 1 0 0 1 1 1 1 NMD3 family Ago_PAZ PF18309.1 PRP82139.1 - 0.041 14.5 0.1 0.11 13.2 0.1 1.7 1 0 0 1 1 1 0 Argonaute PAZ domain HypA PF01155.19 PRP82139.1 - 0.074 13.1 7.6 0.46 10.5 3.8 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 PRP82139.1 - 2.3 8.3 15.0 14 5.8 8.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon DUF1289 PF06945.13 PRP82139.1 - 4.5 7.1 8.1 2.7 7.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) HATPase_c PF02518.26 PRP82141.1 - 7.8e-28 97.2 0.2 2.1e-27 95.9 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP82141.1 - 6.3e-20 71.4 7.3 1.1e-18 67.5 0.2 3.3 4 0 0 4 4 4 2 Response regulator receiver domain HATPase_c_3 PF13589.6 PRP82141.1 - 0.0027 17.5 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BRCT_3 PF18428.1 PRP82141.1 - 0.0042 17.1 0.1 0.53 10.4 0.0 3.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Sec1 PF00995.23 PRP82141.1 - 0.018 14.3 0.1 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Sec1 family HisKA PF00512.25 PRP82141.1 - 0.045 13.8 0.5 0.66 10.1 0.1 3.1 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 PRP82141.1 - 0.094 12.8 0.5 2.9 8.0 0.0 3.1 3 0 0 3 3 3 0 PAS domain GTP_EFTU PF00009.27 PRP82144.1 - 1.1e-23 83.8 0.1 2.7e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PRP82144.1 - 3.9e-06 27.2 2.0 1.1e-05 25.8 0.1 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 PRP82144.1 - 2.6e-05 24.5 0.5 2.6e-05 24.5 0.5 2.8 3 1 0 3 3 3 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 PRP82144.1 - 0.00074 19.3 0.2 1.6 8.4 0.1 3.5 2 1 1 3 3 3 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 PRP82144.1 - 0.00098 19.2 0.5 0.0045 17.1 0.5 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP82144.1 - 0.0065 16.4 0.4 3.9 7.4 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase RR_TM4-6 PF06459.12 PRP82144.1 - 1.2 8.9 14.2 1.9 8.2 14.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Dynamin_N PF00350.23 PRP82144.1 - 5.5 7.0 7.4 0.63 10.1 0.2 2.6 2 1 0 2 2 2 0 Dynamin family Aldo_ket_red PF00248.21 PRP82145.1 - 1.1e-30 106.9 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AAA_12 PF13087.6 PRP82146.1 - 1.5e-49 168.4 0.0 8e-49 166.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PRP82146.1 - 3.2e-31 109.1 0.1 1.8e-16 60.7 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 PRP82146.1 - 1.8e-13 50.7 0.0 4.7e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP82146.1 - 3e-10 40.6 0.0 1.4e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 PRP82146.1 - 1.6e-05 25.0 0.0 0.00049 20.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 PRP82146.1 - 0.00075 19.4 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 PRP82146.1 - 0.0015 19.0 0.0 0.0031 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 PRP82146.1 - 0.0028 18.1 0.0 0.0067 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 PRP82146.1 - 0.0068 16.2 0.2 0.044 13.6 0.2 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 PRP82146.1 - 0.023 15.0 0.0 0.074 13.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain UvrD-helicase PF00580.21 PRP82146.1 - 0.027 14.0 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_5 PF07728.14 PRP82146.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PIF1 PF05970.14 PRP82146.1 - 0.11 11.7 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase Viral_helicase1 PF01443.18 PRP82146.1 - 0.14 11.9 0.1 17 5.0 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 PRP82146.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Ank_2 PF12796.7 PRP82148.1 - 1.5e-11 44.7 0.2 7.5e-11 42.5 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82148.1 - 6.3e-10 39.4 0.2 3e-07 30.9 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82148.1 - 1.1e-09 38.4 0.0 3.9e-09 36.6 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP82148.1 - 3.8e-09 36.6 0.0 0.00037 20.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 PRP82148.1 - 1e-06 28.6 0.0 0.15 12.7 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat EGF_2 PF07974.13 PRP82148.1 - 0.26 11.7 3.8 0.71 10.3 3.8 1.7 1 0 0 1 1 1 0 EGF-like domain YrhK PF14145.6 PRP82149.1 - 0.12 12.2 0.6 6.8 6.7 0.3 2.3 2 0 0 2 2 2 0 YrhK-like protein TRAPPC9-Trs120 PF08626.11 PRP82150.1 - 1.5e-85 287.6 0.2 4.9e-64 216.3 0.0 3.2 1 1 2 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC-Trs85 PF12739.7 PRP82150.1 - 0.00012 21.2 0.6 0.00017 20.7 0.6 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit zf-TAZ PF02135.16 PRP82153.1 - 0.95 10.0 6.3 1.5 9.3 6.3 1.4 1 0 0 1 1 1 0 TAZ zinc finger Ku_C PF03730.14 PRP82154.1 - 0.12 13.1 0.0 0.41 11.4 0.1 1.8 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm DUF3883 PF13020.6 PRP82155.1 - 6.3e-06 26.1 0.0 1.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) DUF4678 PF15727.5 PRP82155.1 - 0.068 12.4 1.4 0.15 11.3 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) Trp_dioxygenase PF03301.13 PRP82156.1 - 7.4e-105 351.1 6.3 9.8e-105 350.7 6.3 1.1 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase DUF244 PF03112.14 PRP82156.1 - 0.027 14.3 0.5 0.051 13.4 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DEAD PF00270.29 PRP82157.1 - 2.6e-46 157.6 0.0 8.2e-46 156.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP82157.1 - 1.2e-24 86.8 0.4 1.7e-23 83.1 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PRP82157.1 - 5.8e-14 52.1 0.2 2.2e-13 50.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PRP82157.1 - 1.1e-05 25.6 0.0 6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 PRP82158.1 - 2.9e-23 81.6 5.8 1.1e-10 41.2 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein TBCC PF07986.12 PRP82158.1 - 1.4e-14 53.9 1.6 3e-14 52.8 1.6 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C WH2 PF02205.20 PRP82160.1 - 5.8e-09 35.5 2.5 0.0024 17.6 0.2 3.4 3 1 0 3 3 3 3 WH2 motif Thymosin PF01290.20 PRP82160.1 - 0.00075 19.2 4.2 0.51 10.1 0.1 2.6 2 1 0 2 2 2 2 Thymosin beta-4 family Peptidase_M24 PF00557.24 PRP82161.1 - 2.5e-46 158.0 0.2 4.3e-46 157.3 0.2 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 PRP82161.1 - 1.3e-14 54.2 7.2 2.9e-14 53.1 7.2 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding TPR_1 PF00515.28 PRP82161.1 - 7.7e-09 35.0 6.7 0.0016 18.2 3.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82161.1 - 8e-09 35.0 6.4 0.069 13.3 2.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-MYND PF01753.18 PRP82161.1 - 0.00011 22.3 8.3 0.00026 21.0 8.3 1.7 1 0 0 1 1 1 1 MYND finger TPR_17 PF13431.6 PRP82161.1 - 0.0005 20.3 0.8 0.0058 16.9 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP82161.1 - 0.0062 17.2 0.2 0.78 10.4 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP82161.1 - 0.0075 15.9 1.2 0.024 14.3 0.3 2.2 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 PRP82161.1 - 0.066 13.5 4.7 5.8 7.4 1.7 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 PRP82161.1 - 0.13 12.4 0.2 1.3 9.2 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP82161.1 - 0.15 12.9 0.6 20 6.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ubiquitin PF00240.23 PRP82162.1 - 1.1e-09 37.9 0.4 1.9e-09 37.1 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP82162.1 - 0.013 15.3 0.4 0.029 14.2 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 PRP82162.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Peptidase_M16 PF00675.20 PRP82163.1 - 0.14 12.2 0.5 0.41 10.6 0.3 1.8 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) STT3 PF02516.14 PRP82164.1 - 2.7e-126 422.4 44.4 7.5e-123 411.0 40.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ParcG PF10274.9 PRP82165.1 - 9.3e-82 273.6 0.1 1.1e-81 273.3 0.1 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 PRP82165.1 - 0.004 16.9 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Hamartin PF04388.12 PRP82165.1 - 2.2 6.8 7.3 3 6.4 7.3 1.1 1 0 0 1 1 1 0 Hamartin protein Atg14 PF10186.9 PRP82166.1 - 4.7e-19 68.6 24.3 3.5e-12 46.0 0.1 2.7 2 1 1 3 3 3 2 Vacuolar sorting 38 and autophagy-related subunit 14 F-box-like PF12937.7 PRP82166.1 - 0.017 15.0 0.7 0.017 15.0 0.7 2.7 3 0 0 3 3 3 0 F-box-like F-box PF00646.33 PRP82166.1 - 0.27 11.1 2.7 0.38 10.7 0.2 2.6 3 0 0 3 3 3 0 F-box domain RasGEF PF00617.19 PRP82168.1 - 1.3e-47 162.3 0.3 2.4e-47 161.4 0.3 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP82168.1 - 3.8e-18 65.7 0.0 1.5e-17 63.7 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif F-box PF00646.33 PRP82168.1 - 0.00028 20.7 1.6 0.00052 19.8 0.8 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP82168.1 - 0.0032 17.3 0.7 0.015 15.2 0.3 2.2 2 0 0 2 2 2 1 F-box-like PRC2_HTH_1 PF18118.1 PRP82168.1 - 0.012 16.4 15.3 0.035 14.9 6.5 2.6 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Vfa1 PF08432.10 PRP82168.1 - 4 7.7 27.7 1.6 9.0 16.5 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.25 PRP82169.1 - 6.6e-61 206.0 0.0 9.9e-61 205.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PH_3 PF14593.6 PRP82169.1 - 4.9e-36 123.0 2.0 1e-35 121.9 2.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 PRP82169.1 - 2.8e-29 102.2 0.0 4.3e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP82169.1 - 0.00064 19.1 0.1 0.0073 15.7 0.0 2.6 3 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 PRP82169.1 - 0.0048 15.7 0.1 0.01 14.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 PRP82169.1 - 0.012 15.2 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PGPGW PF09656.10 PRP82170.1 - 0.41 10.2 5.9 0.69 9.5 5.9 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) FtsJ PF01728.19 PRP82171.1 - 2.4e-46 158.1 0.0 8.9e-46 156.2 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 PRP82171.1 - 0.0046 15.1 0.0 0.0058 14.7 0.0 1.1 1 0 0 1 1 1 1 Virus-capping methyltransferase Rap_GAP PF02145.15 PRP82173.1 - 2e-116 386.1 0.1 4e-59 199.3 0.0 2.7 2 0 0 2 2 2 2 Rap/ran-GAP Ras PF00071.22 PRP82173.1 - 9.7e-26 90.3 0.3 4.1e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Ras family RicinB_lectin_2 PF14200.6 PRP82173.1 - 1.4e-12 48.2 4.1 1.1e-05 26.0 0.0 3.2 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Roc PF08477.13 PRP82173.1 - 8.5e-12 45.4 0.0 2.5e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP82173.1 - 2.5e-05 23.8 0.9 8.1e-05 22.1 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP82173.1 - 0.00045 20.3 0.3 0.0046 17.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 PRP82173.1 - 0.018 14.5 0.0 0.047 13.1 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2718 PF10918.8 PRP82173.1 - 3.1 8.3 5.0 7.5 7.1 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) TPX2_importin PF12214.8 PRP82174.1 - 1.9e-15 57.5 82.9 1.2e-11 45.2 6.5 8.1 3 2 4 7 7 7 3 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 PRP82174.1 - 1.1e-08 35.1 13.2 1.1e-08 35.1 13.2 6.4 7 0 0 7 7 7 1 Targeting protein for Xklp2 (TPX2) Aurora-A_bind PF09041.10 PRP82174.1 - 0.1 12.7 0.4 0.26 11.4 0.4 1.6 1 0 0 1 1 1 0 Aurora-A binding RasGAP PF00616.19 PRP82175.1 - 1.5e-48 165.3 2.1 1.5e-48 165.3 2.1 3.0 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 PRP82175.1 - 3e-30 105.2 4.9 3e-30 105.2 4.9 2.3 2 0 0 2 2 2 1 RasGAP C-terminus ZapD PF07072.11 PRP82175.1 - 0.004 16.9 2.3 0.004 16.9 2.3 2.0 2 0 0 2 2 2 1 Cell division protein Ribosomal_S8 PF00410.19 PRP82175.1 - 0.64 10.0 3.6 32 4.5 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein S8 Complex1_LYR_2 PF13233.6 PRP82175.1 - 1.1 10.1 14.8 0.26 12.0 2.5 4.1 2 1 1 3 3 3 0 Complex1_LYR-like DUF3605 PF12239.8 PRP82175.1 - 2.1 8.7 9.5 0.12 12.7 2.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3605) AAA PF00004.29 PRP82176.1 - 1.8e-09 38.1 0.4 0.0014 19.1 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP82176.1 - 3.9e-08 33.4 0.0 9.4e-06 25.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PRP82176.1 - 1.1e-07 31.5 0.0 0.00024 20.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 PRP82176.1 - 0.0041 17.1 0.0 0.019 15.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PRP82176.1 - 0.0063 17.0 0.1 0.068 13.7 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 PRP82176.1 - 0.009 16.4 0.1 0.29 11.5 0.0 3.4 2 1 1 3 3 3 1 AAA ATPase domain Roc PF08477.13 PRP82176.1 - 0.04 14.1 0.0 3.7 7.8 0.0 3.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 PRP82176.1 - 0.041 13.6 0.3 1.8 8.2 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.13 PRP82176.1 - 0.057 12.6 0.5 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF4379 PF14311.6 PRP82176.1 - 0.067 13.6 0.6 0.2 12.0 0.6 1.8 1 0 0 1 1 1 0 Probable Zinc-ribbon domain AAA_22 PF13401.6 PRP82176.1 - 0.086 13.1 2.0 16 5.8 0.0 4.7 5 1 0 5 5 4 0 AAA domain RNA_helicase PF00910.22 PRP82176.1 - 0.1 13.0 0.1 8.2 6.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase MCM PF00493.23 PRP82176.1 - 0.16 11.0 0.1 5 6.1 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain ubiquitin PF00240.23 PRP82177.1 - 1.1e-11 44.3 0.2 1.9e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP82177.1 - 1.5e-07 31.1 0.0 5.3e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TerD PF02342.18 PRP82177.1 - 2.6e-05 23.8 0.0 4.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 TerD domain Ubiquitin_5 PF18037.1 PRP82177.1 - 0.007 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.10 PRP82177.1 - 0.01 16.5 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD zf-C3HC4_3 PF13920.6 PRP82177.1 - 0.01 15.7 7.1 0.022 14.6 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP82177.1 - 0.017 15.0 10.1 0.041 13.7 10.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP82177.1 - 0.019 15.3 8.9 0.035 14.5 8.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 PRP82177.1 - 0.071 13.4 6.9 0.16 12.3 6.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Ubiquitin_3 PF14836.6 PRP82177.1 - 0.12 12.3 0.1 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain zf-RING_5 PF14634.6 PRP82177.1 - 0.14 12.1 10.1 0.26 11.3 10.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 PRP82177.1 - 0.16 11.8 8.5 0.41 10.6 8.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PRP82177.1 - 0.22 11.3 2.7 0.51 10.2 2.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 PRP82177.1 - 4.4 7.4 8.1 10 6.2 8.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon HSP70 PF00012.20 PRP82178.1 - 3.5e-248 824.7 11.8 4e-248 824.5 11.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP82178.1 - 4.4e-18 65.2 2.3 1.3e-15 57.1 0.8 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 PRP82178.1 - 0.00095 18.9 0.0 0.0024 17.6 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 PRP82178.1 - 0.0038 16.8 0.4 0.96 8.9 0.1 2.4 1 1 1 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 PRP82178.1 - 0.0096 16.3 9.1 0.58 10.6 1.6 3.8 3 2 0 3 3 3 2 Cell division protein FtsA DNA_pol_A PF00476.20 PRP82180.1 - 1.2e-76 258.3 2.1 6.8e-76 255.7 0.3 2.4 2 1 0 2 2 2 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 PRP82180.1 - 5.6e-39 133.6 0.2 1.4e-38 132.3 0.2 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 PRP82180.1 - 2.5e-14 53.6 0.1 1.1e-13 51.6 0.1 2.2 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.20 PRP82180.1 - 1.9e-09 37.5 0.0 5.9e-09 35.9 0.0 1.9 2 1 0 2 2 2 1 3'-5' exonuclease Cyclin_C_2 PF16899.5 PRP82182.1 - 6.9e-11 42.5 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_N PF00134.23 PRP82182.1 - 1.8e-06 27.7 0.3 3e-06 27.0 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 PRP82182.1 - 0.027 14.5 0.0 0.097 12.7 0.0 1.9 1 1 0 1 1 1 0 Transcription factor TFIIB repeat DNA_meth_N PF18284.1 PRP82182.1 - 0.22 11.5 1.5 14 5.6 0.0 2.7 2 1 0 2 2 2 0 DNA methylase N-terminal domain Pro-kuma_activ PF09286.11 PRP82183.1 - 8.2e-22 78.0 0.5 2.1e-21 76.7 0.1 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain ADAM_CR PF08516.12 PRP82183.1 - 0.039 14.4 1.5 0.1 13.0 1.5 1.7 1 0 0 1 1 1 0 ADAM cysteine-rich Glyco_hydr_30_2 PF14587.6 PRP82184.1 - 1.1e-24 87.8 4.1 1.1e-24 87.8 4.1 2.1 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 AAA_12 PF13087.6 PRP82187.1 - 1.7e-25 89.8 0.1 1.7e-25 89.8 0.1 4.3 3 2 0 3 3 3 1 AAA domain AAA_11 PF13086.6 PRP82187.1 - 1.1e-20 74.5 9.9 2.6e-10 40.6 0.0 3.4 3 0 0 3 3 3 3 AAA domain Viral_helicase1 PF01443.18 PRP82187.1 - 6e-06 26.2 0.0 0.03 14.1 0.0 3.2 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 PRP82187.1 - 1.1e-05 25.1 6.5 0.014 14.9 0.1 3.7 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_30 PF13604.6 PRP82187.1 - 7.8e-05 22.5 0.0 0.00023 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP82187.1 - 0.00012 22.4 0.0 0.00065 20.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 PRP82187.1 - 0.0021 18.1 0.1 0.0021 18.1 0.1 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 PRP82187.1 - 0.077 12.4 0.0 0.34 10.3 0.0 2.1 1 1 0 1 1 1 0 PhoH-like protein Helicase_RecD PF05127.14 PRP82187.1 - 0.097 12.5 0.0 0.097 12.5 0.0 2.4 2 1 1 3 3 3 0 Helicase DUF1996 PF09362.10 PRP82189.1 - 1.8e-73 247.4 0.8 2.6e-73 246.9 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FRG1 PF06229.12 PRP82189.1 - 0.00036 20.3 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 FRG1-like domain RicinB_lectin_2 PF14200.6 PRP82189.1 - 0.02 15.6 9.3 0.027 15.2 2.0 3.1 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like ResIII PF04851.15 PRP82190.1 - 3.4e-20 72.8 0.0 3.4e-20 72.8 0.0 5.7 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP82190.1 - 6.1e-18 65.2 0.1 2e-17 63.5 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP82190.1 - 2e-15 57.0 0.0 7.6e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Otopetrin PF03189.13 PRP82190.1 - 8.1e-05 21.6 0.0 79 1.9 4.4 4.9 3 2 0 3 3 3 0 Otopetrin AAA_22 PF13401.6 PRP82190.1 - 0.00075 19.8 0.0 0.0032 17.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain GAF_2 PF13185.6 PRP82191.1 - 3.3e-08 33.9 0.0 4.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PRP82191.1 - 6.9e-08 33.2 0.0 9.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PRP82191.1 - 0.00012 22.4 0.0 0.00028 21.2 0.0 1.6 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 PRP82192.1 - 4.1e-08 33.9 0.0 5.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 PRP82192.1 - 1.3e-07 32.0 0.0 1.8e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PRP82192.1 - 0.00036 20.9 0.0 0.0014 18.9 0.0 1.9 1 1 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.17 PRP82193.1 - 4.4e-76 255.6 0.0 6.7e-76 255.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82193.1 - 6.7e-52 176.5 0.0 1e-51 175.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_18 PF00704.28 PRP82193.1 - 2e-30 106.6 4.4 2e-30 106.6 4.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP82193.1 - 2.9e-18 66.0 151.1 0.00013 22.3 19.3 7.2 7 0 0 7 7 7 5 Chitin recognition protein Pkinase_fungal PF17667.1 PRP82193.1 - 0.0098 14.7 0.0 0.0098 14.7 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP82193.1 - 0.023 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 PRP82193.1 - 0.031 13.7 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CAS_CSE1 PF03378.15 PRP82193.1 - 0.14 10.6 0.4 0.22 10.0 0.4 1.2 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus Glyco_hydro_18 PF00704.28 PRP82194.1 - 1.2e-54 186.2 11.0 1.4e-54 185.9 11.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP82194.1 - 4.2e-09 36.7 41.8 8.8e-05 22.9 23.5 2.5 1 1 1 2 2 2 2 Chitin recognition protein DUF1961 PF09224.11 PRP82194.1 - 0.14 11.5 0.1 0.53 9.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1961) Ribosomal_L3 PF00297.22 PRP82194.1 - 0.18 10.7 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L3 DUF1856 PF08983.10 PRP82194.1 - 0.57 10.5 1.8 1.6 9.0 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1856) Arrestin_C PF02752.22 PRP82195.1 - 2.3e-10 41.0 0.0 6.8e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PRP82195.1 - 1.1e-09 38.4 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain PAXIP1_C PF15364.6 PRP82195.1 - 0.084 13.2 2.1 0.17 12.2 2.1 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein LDB19 PF13002.7 PRP82195.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like POT1 PF02765.17 PRP82196.1 - 6.7e-20 71.4 0.0 1.1e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 POT1PC PF16686.5 PRP82196.1 - 0.00018 21.4 0.0 0.0021 17.9 0.0 2.3 1 1 0 1 1 1 1 ssDNA-binding domain of telomere protection protein Rep_fac-A_C PF08646.10 PRP82196.1 - 0.0029 17.4 0.7 0.0061 16.3 0.7 1.6 1 0 0 1 1 1 1 Replication factor-A C terminal domain CDC24_OB3 PF17244.2 PRP82196.1 - 0.017 14.8 0.1 0.045 13.4 0.1 1.7 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 DNA_pol_B_2 PF03175.13 PRP82196.1 - 0.069 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DUF5327 PF17261.2 PRP82196.1 - 0.1 13.3 1.0 0.3 11.8 1.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) zf-ribbon_3 PF13248.6 PRP82196.1 - 0.53 9.8 2.5 0.97 8.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.25 PRP82198.1 - 1.5e-33 116.3 0.0 5.9e-33 114.3 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82198.1 - 1.8e-30 106.1 0.0 3.8e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP82198.1 - 1.9e-09 37.2 22.1 3.1e-07 30.0 3.0 4.5 2 2 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 PRP82198.1 - 8.8e-09 35.1 15.4 1.1e-07 31.5 2.4 3.5 3 1 1 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.7 PRP82198.1 - 7.8e-07 29.3 27.9 0.00033 21.0 3.5 5.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) Arm PF00514.23 PRP82198.1 - 8.9e-06 25.6 10.2 0.99 9.6 0.3 6.5 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PRP82198.1 - 0.0063 17.0 4.7 9.1 6.9 0.0 5.5 5 0 0 5 5 5 1 HEAT-like repeat Arm_2 PF04826.13 PRP82198.1 - 0.0065 16.0 2.7 0.0065 16.0 2.7 5.1 4 1 0 5 5 5 1 Armadillo-like Proteasom_PSMB PF10508.9 PRP82198.1 - 0.0086 14.6 0.5 0.0086 14.6 0.5 2.7 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit Kinase-like PF14531.6 PRP82198.1 - 0.033 13.5 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like LRR_6 PF13516.6 PRP82198.1 - 0.67 10.2 6.0 79 3.7 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat DUF3361 PF11841.8 PRP82198.1 - 2.3 8.2 9.1 7.6 6.5 1.1 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) LRR_1 PF00560.33 PRP82198.1 - 2.3 9.1 9.5 1.8e+02 3.3 0.2 5.7 5 1 0 5 5 4 0 Leucine Rich Repeat TBCC PF07986.12 PRP82199.1 - 3.2e-32 110.8 0.4 5e-32 110.1 0.4 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 PRP82199.1 - 0.0006 19.5 0.5 0.0034 17.0 0.2 1.9 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal DUF2367 PF10164.9 PRP82199.1 - 0.055 14.0 0.7 0.28 11.7 0.3 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) TFIIS_M PF07500.14 PRP82200.1 - 1.2e-24 86.9 0.0 1.5e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain RasGEF PF00617.19 PRP82201.1 - 6.6e-44 150.2 1.8 7.6e-44 150.0 0.3 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP82201.1 - 0.00012 22.3 0.5 0.00043 20.5 0.5 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif XylR_N PF06505.11 PRP82201.1 - 0.0012 18.5 0.0 0.0076 16.0 0.0 2.3 2 0 0 2 2 2 1 Activator of aromatic catabolism V4R PF02830.18 PRP82201.1 - 0.045 13.8 2.0 0.094 12.7 2.0 1.5 1 0 0 1 1 1 0 V4R domain RFX_DNA_binding PF02257.15 PRP82203.1 - 9.8e-34 115.8 0.9 2.2e-33 114.7 0.0 2.1 3 0 0 3 3 3 1 RFX DNA-binding domain Pox_D5 PF03288.16 PRP82203.1 - 0.033 14.7 0.1 0.22 12.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus D5 protein-like PH PF00169.29 PRP82204.1 - 0.0057 17.1 0.1 0.016 15.7 0.1 1.8 1 0 0 1 1 1 1 PH domain Aminotran_3 PF00202.21 PRP82205.1 - 1.7e-117 392.6 0.0 2.5e-117 392.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DUF5593 PF18007.1 PRP82205.1 - 0.012 16.3 0.1 0.068 13.9 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5593) OAM_dimer PF16554.5 PRP82205.1 - 0.022 15.2 0.1 0.083 13.3 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Beta_elim_lyase PF01212.21 PRP82205.1 - 0.051 12.8 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase Ovate PF04844.13 PRP82205.1 - 0.18 11.8 0.9 25 4.9 0.0 3.5 3 0 0 3 3 3 0 Transcriptional repressor, ovate Ank_2 PF12796.7 PRP82206.1 - 7.1e-60 199.6 1.4 2.4e-13 50.5 0.1 6.5 3 1 5 8 8 8 7 Ankyrin repeats (3 copies) SIR2 PF02146.17 PRP82206.1 - 1.8e-47 161.6 0.0 2.7e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Ank_4 PF13637.6 PRP82206.1 - 8.8e-43 144.2 4.5 6.9e-09 36.1 0.0 9.0 2 2 8 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82206.1 - 3.8e-37 122.1 2.6 4e-05 23.7 0.0 11.6 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 PRP82206.1 - 8.7e-35 117.7 4.6 0.00061 20.1 0.0 11.6 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 PRP82206.1 - 1.2e-34 117.9 7.3 4.4e-06 26.9 0.1 9.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Glyoxalase_6 PF18029.1 PRP82206.1 - 0.038 14.8 1.1 2.2 9.1 0.0 3.5 3 1 1 4 4 4 0 Glyoxalase-like domain 2_5_RNA_ligase2 PF13563.6 PRP82207.1 - 1.3e-10 41.4 0.0 2.8e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily EI24 PF07264.11 PRP82208.1 - 1.5e-20 74.2 17.9 2e-20 73.8 17.9 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ras PF00071.22 PRP82209.1 - 1e-54 184.5 0.0 1.4e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP82209.1 - 3.3e-21 75.7 0.0 5.7e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP82209.1 - 4.6e-07 29.4 0.0 7.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family 2OG-FeII_Oxy_2 PF13532.6 PRP82209.1 - 0.00038 20.7 0.0 0.0017 18.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DCX PF03607.17 PRP82210.1 - 3.9e-09 36.5 0.3 1.5e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Doublecortin KHA PF11834.8 PRP82210.1 - 2.4e-05 24.3 0.1 7.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel Peptidase_C1 PF00112.23 PRP82211.1 - 5.9e-59 199.8 0.1 9.6e-59 199.1 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP82211.1 - 3.7e-10 40.1 0.4 7.5e-10 39.1 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP82211.1 - 6.2e-06 25.2 0.2 0.0024 16.7 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF1460 PF07313.12 PRP82211.1 - 0.1 12.0 0.5 0.15 11.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Cnd3 PF12719.7 PRP82212.1 - 9.3e-37 126.8 0.4 9.3e-37 126.8 0.4 3.1 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 PRP82212.1 - 1.2e-12 46.9 4.6 0.82 10.1 0.0 8.4 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 PRP82212.1 - 1.1e-11 45.0 2.6 1e-06 29.0 0.2 5.4 4 1 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 PRP82212.1 - 0.0007 19.7 24.9 0.032 14.3 0.3 6.3 5 1 2 7 7 7 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PRP82212.1 - 0.0011 19.4 0.3 9.7 6.8 0.0 4.9 6 0 0 6 6 6 1 HEAT-like repeat BRCT_2 PF16589.5 PRP82212.1 - 0.0057 17.0 0.0 0.063 13.7 0.0 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 PRP82212.1 - 0.0074 16.2 0.0 0.033 14.0 0.0 2.2 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain adh_short_C2 PF13561.6 PRP82214.1 - 1.9e-41 142.2 0.1 2e-40 138.8 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP82214.1 - 1.2e-32 113.0 0.2 9.7e-24 83.9 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 PRP82214.1 - 7.2e-12 45.6 0.0 1.2e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PRP82214.1 - 4.6e-05 22.7 0.0 7.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AAA_6 PF12774.7 PRP82215.1 - 3.7e-154 512.6 0.0 1.3e-152 507.4 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 PRP82215.1 - 5.7e-150 500.6 7.5 5.7e-150 500.6 7.5 3.4 2 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PRP82215.1 - 1e-127 426.5 15.4 1e-127 426.5 15.4 4.2 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PRP82215.1 - 6.9e-96 320.6 1.1 1.2e-95 319.8 0.1 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PRP82215.1 - 2.2e-84 283.3 1.6 7.8e-84 281.5 0.3 2.6 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PRP82215.1 - 1.3e-79 266.4 0.2 1.3e-79 266.4 0.2 2.4 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 PRP82215.1 - 1.9e-79 265.4 1.0 1.5e-72 242.9 0.0 4.1 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PRP82215.1 - 1.4e-56 190.8 0.1 3.5e-56 189.5 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PRP82215.1 - 2e-51 175.1 15.4 5.5e-51 173.6 15.4 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PRP82215.1 - 7.8e-43 145.4 0.0 1.3e-41 141.4 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 PRP82215.1 - 1.6e-30 105.9 0.0 2.5e-09 37.2 0.0 6.0 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PRP82215.1 - 2.4e-28 98.8 0.0 5.9e-27 94.3 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PRP82215.1 - 3.4e-22 78.5 0.7 2.7e-20 72.4 0.0 3.6 3 0 0 3 3 2 1 AAA+ lid domain AAA_22 PF13401.6 PRP82215.1 - 8.4e-14 52.0 2.1 0.00064 20.0 0.0 6.3 7 0 0 7 7 5 2 AAA domain AAA_16 PF13191.6 PRP82215.1 - 4.1e-12 46.8 1.7 0.024 15.0 0.0 6.2 6 0 0 6 6 4 3 AAA ATPase domain AAA PF00004.29 PRP82215.1 - 1.7e-11 44.6 1.8 0.029 14.8 0.1 6.0 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) Peptidase_C48 PF02902.19 PRP82215.1 - 6.3e-07 29.5 0.5 6.3e-07 29.5 0.5 2.3 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain AAA_33 PF13671.6 PRP82215.1 - 1.1e-06 28.9 0.7 0.23 11.6 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 PRP82215.1 - 1.6e-06 28.0 0.7 0.22 11.2 0.0 3.9 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.26 PRP82215.1 - 1.1e-05 25.2 0.0 0.094 12.4 0.0 3.9 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 PRP82215.1 - 1.1e-05 26.0 0.3 3.6 8.2 0.0 4.7 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 PRP82215.1 - 1.5e-05 24.9 2.5 0.055 13.4 0.0 4.4 4 0 0 4 4 3 2 RsgA GTPase RNA_helicase PF00910.22 PRP82215.1 - 0.00042 20.7 0.1 21 5.5 0.0 4.0 3 0 0 3 3 3 0 RNA helicase T2SSE PF00437.20 PRP82215.1 - 0.00066 18.8 0.9 1.5 7.8 0.0 3.5 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_24 PF13479.6 PRP82215.1 - 0.00094 19.0 1.1 8.3 6.1 0.1 4.1 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 PRP82215.1 - 0.0021 17.5 0.0 5.3 6.4 0.0 3.7 4 0 0 4 4 3 0 Bacterial TniB protein AAA_29 PF13555.6 PRP82215.1 - 0.0048 16.6 0.2 25 4.7 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain PhoH PF02562.16 PRP82215.1 - 0.0049 16.3 0.2 1.3 8.4 0.0 3.5 3 0 0 3 3 3 1 PhoH-like protein NACHT PF05729.12 PRP82215.1 - 0.0076 16.2 0.1 8.7 6.2 0.0 4.1 3 0 0 3 3 3 0 NACHT domain Rad17 PF03215.15 PRP82215.1 - 0.011 15.7 0.4 7.8 6.4 0.1 4.2 3 0 0 3 3 3 0 Rad17 P-loop domain TsaE PF02367.17 PRP82215.1 - 0.012 15.6 1.8 25 4.9 0.0 3.9 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF853 PF05872.12 PRP82215.1 - 0.014 14.0 0.6 0.12 10.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Mg_chelatase PF01078.21 PRP82215.1 - 0.014 14.7 0.0 11 5.3 0.0 3.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 PRP82215.1 - 0.031 14.5 0.3 0.39 11.0 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase BAR_3_WASP_bdg PF10456.9 PRP82215.1 - 0.035 13.6 0.5 0.19 11.2 0.0 2.5 2 0 0 2 2 1 0 WASP-binding domain of Sorting nexin protein AAA_19 PF13245.6 PRP82215.1 - 0.039 14.3 3.4 40 4.5 0.0 4.4 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 PRP82215.1 - 0.047 14.2 4.0 11 6.6 0.1 4.5 4 0 0 4 4 3 0 ABC transporter AAA_25 PF13481.6 PRP82215.1 - 0.057 13.0 0.0 11 5.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PRP82215.1 - 0.06 13.6 0.1 39 4.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain Herpes_TAF50 PF03326.13 PRP82215.1 - 0.55 8.8 6.4 1.1 7.8 6.4 1.4 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF406 PF04175.12 PRP82215.1 - 7 7.2 5.9 1.1e+02 3.4 2.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF406) Chromo PF00385.24 PRP82216.1 - 3.1e-10 39.8 0.0 4.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP82216.1 - 0.073 13.2 0.4 0.12 12.5 0.4 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 MSV199 PF10553.9 PRP82217.1 - 0.0019 18.4 0.3 0.0058 16.9 0.3 1.8 1 0 0 1 1 1 1 MSV199 domain Peptidase_C97 PF05903.14 PRP82218.1 - 0.017 15.0 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain ATG27 PF09451.10 PRP82219.1 - 1.9e-09 37.8 0.0 3.7e-09 36.8 0.0 1.4 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 PRP82219.1 - 1.6e-08 34.0 0.0 2.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor DUF456 PF04306.13 PRP82219.1 - 0.044 14.1 0.5 0.044 14.1 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF4690 PF15756.5 PRP82219.1 - 0.051 14.2 0.4 0.11 13.2 0.4 1.4 1 0 0 1 1 1 0 Small Novel Rich in Cartilage VWA PF00092.28 PRP82220.1 - 1.1e-15 58.3 0.0 2.7e-15 57.1 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP82220.1 - 2.2e-09 37.9 0.0 1.1e-08 35.6 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Dicty_CTDC PF00526.18 PRP82220.1 - 3.8e-07 29.9 15.3 3.8e-07 29.9 15.3 10.8 10 1 1 11 11 11 5 Dictyostelium (slime mold) repeat DUF1194 PF06707.11 PRP82220.1 - 0.0018 17.5 0.1 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1194) SHR-BD PF06650.12 PRP82221.1 - 2e-16 60.2 0.0 4.6e-14 52.4 0.0 2.8 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 PRP82221.1 - 1e-07 32.1 0.1 1e-06 28.8 0.0 2.8 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 PRP82221.1 - 4.3e-05 23.4 0.0 0.00014 21.7 0.0 1.9 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 PRP82221.1 - 6.2e-05 23.3 0.0 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_mid_rpt PF16910.5 PRP82221.1 - 0.0086 15.5 1.9 0.38 10.1 0.3 2.7 2 0 0 2 2 2 1 Repeating coiled region of VPS13 Glyco_hydro_81 PF03639.13 PRP82221.1 - 0.065 12.4 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 N-terminal domain FH2 PF02181.23 PRP82222.1 - 7.5e-76 255.6 9.6 7.5e-76 255.6 9.6 2.6 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PRP82222.1 - 1.1e-21 77.4 5.0 1.1e-21 77.4 5.0 3.6 4 1 1 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP82222.1 - 1.7e-13 50.6 1.0 6.1e-13 48.8 1.0 2.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Baculo_PEP_C PF04513.12 PRP82222.1 - 0.06 13.4 10.6 0.12 12.4 3.0 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TetR_C_4 PF08359.11 PRP82222.1 - 0.15 12.2 4.0 1.8 8.7 0.3 3.4 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region ZapD PF07072.11 PRP82222.1 - 0.17 11.6 5.5 0.062 13.0 0.5 2.8 3 0 0 3 3 3 0 Cell division protein ZYG-11_interact PF05884.12 PRP82222.1 - 0.5 9.7 2.5 0.46 9.8 0.6 1.8 2 0 0 2 2 2 0 Interactor of ZYG-11 LURAP PF14854.6 PRP82222.1 - 0.86 9.6 12.2 4.5 7.3 0.9 3.6 3 0 0 3 3 3 0 Leucine rich adaptor protein Bacillus_HBL PF05791.11 PRP82222.1 - 2.7 7.8 17.8 0.19 11.6 5.4 3.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF2154 PF09922.9 PRP82223.1 - 0.052 13.4 3.6 2.7 7.9 0.2 2.9 2 1 1 3 3 3 0 Cell wall-active antibiotics response 4TMS YvqF TauD PF02668.16 PRP82224.1 - 6.7e-39 134.3 0.0 9.3e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 PRP82224.1 - 2e-08 34.7 1.2 4.9e-07 30.3 0.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.10 PRP82224.1 - 0.004 16.3 0.0 0.0055 15.9 0.0 1.2 1 0 0 1 1 1 1 CsiD DUF3444 PF11926.8 PRP82225.1 - 0.15 11.7 0.0 0.45 10.1 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3444) Glycos_transf_3 PF00591.21 PRP82226.1 - 3.6e-74 249.6 0.0 4.9e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 PRP82226.1 - 9.4e-13 47.8 0.2 2e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PNP_UDP_1 PF01048.20 PRP82227.1 - 1.4e-27 96.5 0.0 1.7e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Gas_vesicle_C PF01304.17 PRP82227.1 - 0.26 11.3 0.3 3.7 7.6 0.3 2.3 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain Toxin_27 PF08099.11 PRP82228.1 - 0.12 12.6 0.1 0.31 11.2 0.1 1.7 1 0 0 1 1 1 0 Scorpion calcine family Myb_DNA-binding PF00249.31 PRP82229.1 - 3.2e-50 168.1 13.3 3.1e-17 62.5 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP82229.1 - 5.9e-37 125.7 10.3 1.1e-16 60.8 0.2 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PRP82229.1 - 3.6e-05 23.6 2.0 0.0026 17.6 0.1 3.1 1 1 2 3 3 3 1 Myb DNA-binding like SLIDE PF09111.10 PRP82229.1 - 8.1e-05 22.6 0.1 0.32 11.0 0.0 3.6 1 1 2 3 3 3 2 SLIDE Rap1_C PF11626.8 PRP82229.1 - 0.00034 20.7 6.0 0.17 12.0 1.7 3.4 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Mito_carr PF00153.27 PRP82230.1 - 3e-72 238.6 1.7 6.2e-26 90.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PSDC PF12588.8 PRP82231.1 - 0.11 12.5 0.0 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Phophatidylserine decarboxylase PAS PF00989.25 PRP82231.1 - 0.12 12.4 0.0 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 PAS fold Aminotran_3 PF00202.21 PRP82232.1 - 3.8e-110 368.3 0.0 5.5e-110 367.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 PRP82232.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Flavin_Reduct PF01613.18 PRP82233.1 - 1e-13 51.6 0.2 1.4e-13 51.2 0.2 1.1 1 0 0 1 1 1 1 Flavin reductase like domain GSHPx PF00255.19 PRP82234.1 - 2e-39 133.5 0.4 5.6e-39 132.1 0.1 1.8 2 0 0 2 2 2 1 Glutathione peroxidase Redoxin PF08534.10 PRP82234.1 - 0.059 13.1 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Redoxin ABC2_membrane_3 PF12698.7 PRP82234.1 - 0.12 11.5 0.3 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein GDP_Man_Dehyd PF16363.5 PRP82235.1 - 2.3e-50 171.9 0.0 3.1e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PRP82235.1 - 1.1e-45 156.1 0.0 1.4e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PRP82235.1 - 1.2e-12 47.6 0.0 7.3e-07 28.6 0.0 2.2 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PRP82235.1 - 4.2e-10 39.2 0.0 6.4e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 PRP82235.1 - 2.5e-08 33.3 0.0 6.6e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PRP82235.1 - 6e-05 22.3 0.0 8.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Myosin_head PF00063.21 PRP82237.1 - 2.7e-113 379.5 1.5 3.9e-113 379.0 1.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Y_phosphatase PF00102.27 PRP82237.1 - 5.5e-60 202.9 0.1 2.7e-59 200.6 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Pkinase PF00069.25 PRP82237.1 - 1.2e-27 97.0 0.0 2.4e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82237.1 - 1e-18 67.6 0.0 2.6e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PTPlike_phytase PF14566.6 PRP82237.1 - 0.00086 19.4 1.2 1.5 8.9 0.1 3.3 3 0 0 3 3 3 2 Inositol hexakisphosphate DSPc PF00782.20 PRP82237.1 - 0.0032 17.3 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Kinase-like PF14531.6 PRP82237.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RhoGEF PF00621.20 PRP82237.1 - 0.0087 16.3 0.9 0.19 11.9 0.0 3.4 4 0 0 4 4 4 1 RhoGEF domain Y_phosphatase3 PF13350.6 PRP82237.1 - 0.09 12.7 0.0 0.44 10.5 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family DUF2336 PF10098.9 PRP82237.1 - 0.28 10.6 1.2 6.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) Chromo PF00385.24 PRP82238.1 - 3.6e-17 62.0 1.8 3.8e-16 58.7 1.5 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 PRP82238.1 - 7.9e-13 48.3 0.3 2.7e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 Chromo shadow domain Ndc1_Nup PF09531.10 PRP82238.1 - 0.0074 15.0 3.8 0.0085 14.8 3.8 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 PRP82238.1 - 0.056 12.3 3.8 0.08 11.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RAB3GAP2_C PF14656.6 PRP82238.1 - 0.12 10.6 0.0 0.12 10.6 0.0 2.3 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Tudor_3 PF18115.1 PRP82238.1 - 0.14 12.0 0.1 8.8 6.3 0.1 2.5 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain ALMT PF11744.8 PRP82238.1 - 5.2 5.8 5.9 9.7 4.9 5.9 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter SH3_9 PF14604.6 PRP82239.1 - 1.7e-14 53.4 0.3 3.1e-14 52.5 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP82239.1 - 2.4e-13 49.4 0.0 4.6e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP82239.1 - 2.1e-07 30.5 0.0 4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF5598 PF18127.1 PRP82240.1 - 0.15 12.5 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5598) Abhydrolase_1 PF00561.20 PRP82241.1 - 8.5e-18 64.9 0.0 2.8e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP82241.1 - 7.5e-10 39.8 0.0 1e-09 39.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP82241.1 - 2.3e-09 36.9 0.3 9.6e-09 34.8 0.3 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 PRP82241.1 - 0.00013 21.7 0.0 0.011 15.3 0.0 2.6 3 0 0 3 3 3 1 Dienelactone hydrolase family UPF0227 PF05728.12 PRP82241.1 - 0.0064 16.5 0.2 0.6 10.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 PRP82241.1 - 0.04 13.8 0.1 0.62 9.9 0.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 PRP82241.1 - 0.054 13.2 0.0 0.28 10.8 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 PRP82241.1 - 0.083 13.0 0.1 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain DUF5383 PF17355.2 PRP82242.1 - 0.59 10.5 0.1 0.59 10.5 0.1 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5383) tRNA-synt_1d PF00750.19 PRP82243.1 - 7.6e-44 150.1 0.3 2.5e-23 82.6 0.4 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 PRP82243.1 - 1.2e-22 80.3 0.0 2.7e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA_bind PF01588.20 PRP82243.1 - 7.1e-05 22.8 0.5 0.00041 20.4 0.2 2.3 2 0 0 2 2 2 1 Putative tRNA binding domain Peptidase_S49_N PF08496.10 PRP82243.1 - 0.96 9.5 5.5 2.1 8.4 5.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.8 PRP82243.1 - 10 4.9 12.9 16 4.3 12.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PDEase_I PF00233.19 PRP82244.1 - 6.7e-78 261.7 0.6 6.7e-78 261.7 0.6 2.6 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase PRCC PF10253.9 PRP82246.1 - 0.26 12.1 32.8 1.9e+02 2.7 32.8 3.0 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ATP-grasp_2 PF08442.10 PRP82248.1 - 5.3e-70 235.1 4.8 9.4e-69 231.0 4.8 2.2 1 1 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 PRP82248.1 - 5.4e-26 91.2 1.1 1.1e-25 90.3 1.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 PRP82248.1 - 2.7e-10 40.1 0.1 7.1e-10 38.7 0.1 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 PRP82248.1 - 9.4e-05 22.3 0.1 0.00023 21.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 PRP82248.1 - 0.032 14.0 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain RhoGAP PF00620.27 PRP82249.1 - 1.3e-28 99.7 0.0 2.2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Pectate_lyase_3 PF12708.7 PRP82249.1 - 1.9e-05 24.6 5.0 0.00011 22.1 5.0 2.2 1 1 0 1 1 1 1 Pectate lyase superfamily protein DUF4955 PF16315.5 PRP82249.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) Pectate_lyase_3 PF12708.7 PRP82251.1 - 0.00017 21.5 1.5 0.00017 21.5 1.5 2.4 2 1 1 3 3 3 1 Pectate lyase superfamily protein DUF4955 PF16315.5 PRP82251.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) ALO PF04030.14 PRP82252.1 - 1.7e-45 155.9 1.2 2.3e-45 155.4 1.2 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 PRP82252.1 - 1.7e-22 79.6 0.0 3.4e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pcc1 PF09341.10 PRP82254.1 - 2.9e-14 53.0 0.0 3.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF658 PF04936.12 PRP82254.1 - 0.029 14.1 0.0 0.034 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF658) IBR PF01485.21 PRP82255.1 - 3.7e-11 43.1 34.6 1.6e-08 34.7 9.9 4.0 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PRP82255.1 - 0.0024 18.2 2.6 0.0024 18.2 2.6 3.8 3 1 1 4 4 4 2 Ring finger domain DUF4802 PF16060.5 PRP82255.1 - 0.0043 17.2 2.9 0.015 15.4 2.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4802) Cep57_CLD_2 PF14197.6 PRP82255.1 - 0.023 14.8 7.0 0.039 14.0 7.0 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Msap1 PF17077.5 PRP82255.1 - 0.088 12.0 0.7 0.13 11.4 0.7 1.1 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 zf-RING_UBOX PF13445.6 PRP82255.1 - 0.91 9.6 18.5 0.086 12.9 1.4 3.4 2 2 1 3 3 3 0 RING-type zinc-finger Aldedh PF00171.22 PRP82257.1 - 1.1e-147 492.3 0.1 1.3e-147 492.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 PRP82257.1 - 0.0039 16.3 0.1 0.0081 15.3 0.1 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 PRP82257.1 - 0.094 12.1 0.1 0.19 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF4336 PF14234.6 PRP82259.1 - 2.3e-11 43.5 0.0 1.2e-08 34.5 0.0 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4336) Bclt PF15318.6 PRP82260.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis FliS_cochap PF16522.5 PRP82261.1 - 0.006 16.5 1.2 0.0069 16.3 1.2 1.2 1 0 0 1 1 1 1 Flagellar FLiS export co-chaperone, HP1076 Phage_P2_GpU PF06995.11 PRP82261.1 - 0.059 13.0 0.6 0.084 12.5 0.6 1.3 1 1 0 1 1 1 0 Phage P2 GpU DUF4407 PF14362.6 PRP82261.1 - 0.14 11.5 2.6 0.16 11.3 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BAH PF01426.18 PRP82262.1 - 0.00023 21.0 0.1 0.00023 21.0 0.1 2.4 2 1 0 2 2 2 1 BAH domain BRCT PF00533.26 PRP82263.1 - 0.04 14.3 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Fib_alpha PF08702.10 PRP82264.1 - 0.0068 16.6 13.1 0.0068 16.6 13.1 7.4 2 1 5 8 8 8 2 Fibrinogen alpha/beta chain family Rad52_Rad22 PF04098.15 PRP82265.1 - 4e-12 46.3 0.2 1.1e-11 44.9 0.2 1.7 1 1 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 PRP82265.1 - 9.4e-06 25.4 0.1 0.00044 20.0 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 PRP82266.1 - 1.6e-63 214.5 2.1 7.6e-63 212.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82266.1 - 1.2e-42 146.0 0.0 2.4e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP82266.1 - 5.4e-08 32.0 4.4 1.2e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase RPEL PF02755.15 PRP82266.1 - 0.00082 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 RPEL repeat Kinase-like PF14531.6 PRP82266.1 - 0.00089 18.7 0.0 0.02 14.2 0.0 2.2 1 1 0 2 2 2 1 Kinase-like PBP_sp32 PF07222.12 PRP82266.1 - 0.085 12.3 4.4 0.14 11.6 4.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 zf-C2H2_3rep PF18868.1 PRP82266.1 - 0.12 13.1 3.7 0.86 10.3 0.0 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Cytomega_UL84 PF06284.11 PRP82266.1 - 0.8 8.1 4.3 1.2 7.5 4.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Presenilin PF01080.17 PRP82266.1 - 4.4 6.0 4.8 6.2 5.5 4.8 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 PRP82266.1 - 7.7 6.6 11.0 14 5.8 11.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal La PF05383.17 PRP82267.1 - 3.3e-19 68.7 0.1 6.1e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 PRP82267.1 - 9.4e-18 64.1 2.8 3.5e-15 55.9 0.0 3.4 2 1 1 3 3 3 1 RNA binding motif RRM_1 PF00076.22 PRP82267.1 - 1.8e-07 30.9 0.0 0.047 13.5 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_lid_3 PF17862.1 PRP82267.1 - 0.16 11.8 0.9 0.41 10.5 0.9 1.6 1 0 0 1 1 1 0 AAA+ lid domain Mucin_bdg PF03272.13 PRP82267.1 - 0.29 11.2 2.6 0.3 11.1 0.1 2.3 3 0 0 3 3 3 0 Putative mucin or carbohydrate-binding module PCI PF01399.27 PRP82268.1 - 1.4e-12 48.1 1.1 2.6e-12 47.2 0.3 1.8 2 0 0 2 2 2 1 PCI domain Paf67 PF10255.9 PRP82268.1 - 0.057 12.4 1.3 0.37 9.8 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-associated factor PAF67 TPR_8 PF13181.6 PRP82268.1 - 0.59 10.5 3.7 0.64 10.4 1.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82268.1 - 0.77 10.0 2.5 0.88 9.8 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Dpy-30 PF05186.13 PRP82269.1 - 8.1e-19 67.0 0.3 1.3e-18 66.4 0.3 1.3 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 PRP82269.1 - 0.057 13.1 0.2 0.19 11.5 0.1 1.7 1 1 1 2 2 2 0 Regulatory subunit of type II PKA R-subunit Xpo1 PF08389.12 PRP82270.1 - 3.6e-10 40.1 1.5 1.5e-07 31.6 0.0 3.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 PRP82270.1 - 0.00079 19.3 1.7 0.00079 19.3 1.7 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain TMIE PF16038.5 PRP82271.1 - 2.3 8.1 5.9 2.8 7.8 0.6 2.3 1 1 1 2 2 2 0 TMIE protein Amino_oxidase PF01593.24 PRP82273.1 - 2.2e-45 155.8 0.0 3.8e-45 155.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DOMON PF03351.17 PRP82273.1 - 3.4e-44 150.1 8.7 1.9e-22 79.8 0.5 2.7 2 0 0 2 2 2 2 DOMON domain Ferric_reduct PF01794.19 PRP82273.1 - 4.6e-22 78.5 11.1 9.1e-22 77.5 11.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 PRP82273.1 - 6.3e-14 52.4 0.0 3.1e-07 30.6 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PRP82273.1 - 3.6e-12 46.3 0.0 2.4e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_8 PF13450.6 PRP82273.1 - 1.1e-08 35.1 0.0 2.9e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_1 PF00175.21 PRP82273.1 - 2.7e-06 28.0 0.0 7.1e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_oxidored PF12831.7 PRP82273.1 - 0.00066 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PRP82273.1 - 0.0007 18.9 0.9 0.0013 18.0 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP82273.1 - 0.0018 17.5 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP82273.1 - 0.0077 15.5 0.2 0.017 14.4 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP82273.1 - 0.0093 14.7 0.3 0.016 13.9 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 PRP82273.1 - 0.019 14.1 0.2 0.046 12.8 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 PRP82273.1 - 0.02 14.0 0.7 0.061 12.4 0.7 1.8 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 PRP82273.1 - 0.1 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase zf-C2H2_jaz PF12171.8 PRP82274.1 - 1.8e-05 24.8 0.1 3.1e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP82274.1 - 0.00062 20.1 0.3 0.00095 19.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CTU2 PF10288.9 PRP82274.1 - 0.057 13.7 11.2 0.79 10.0 11.2 2.2 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Presenilin PF01080.17 PRP82274.1 - 0.12 11.1 0.7 0.11 11.3 0.7 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 PRP82274.1 - 1 9.2 10.4 0.045 13.6 4.3 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Phage_CII PF05269.11 PRP82275.1 - 0.084 13.1 0.0 1.3e+02 2.8 0.0 3.9 4 0 0 4 4 4 0 Bacteriophage CII protein Securin PF04856.13 PRP82275.1 - 0.086 12.8 0.1 0.26 11.2 0.0 1.7 1 1 0 2 2 2 0 Securin sister-chromatid separation inhibitor Arg_decarbox_C PF17944.1 PRP82275.1 - 0.1 13.2 2.4 0.18 12.4 0.4 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Mlh1_C PF16413.5 PRP82276.1 - 1.1e-60 205.3 0.1 1.8e-60 204.6 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 PRP82276.1 - 5e-26 90.7 0.0 8.7e-26 89.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PRP82276.1 - 3.2e-14 52.9 0.0 6.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PRP82276.1 - 3.3e-08 34.0 0.0 7.5e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M60 PF13402.6 PRP82276.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like Ank_2 PF12796.7 PRP82277.1 - 8e-41 138.5 0.0 3.6e-08 33.9 0.0 6.5 2 2 5 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82277.1 - 5e-23 81.2 10.5 0.0051 17.4 0.2 9.7 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82277.1 - 6.6e-16 58.2 12.7 0.029 14.7 0.0 9.9 6 4 5 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP82277.1 - 8e-16 57.7 8.7 6.9 7.3 0.0 11.8 13 0 0 13 13 13 6 Ankyrin repeat Ank_3 PF13606.6 PRP82277.1 - 2.4e-15 55.1 2.4 0.72 10.6 0.0 11.3 12 0 0 12 12 12 2 Ankyrin repeat Secretogranin_V PF05281.11 PRP82277.1 - 0.00012 21.8 1.1 0.23 11.1 0.0 4.1 3 1 1 4 4 4 2 Neuroendocrine protein 7B2 precursor (Secretogranin V) GST_N PF02798.20 PRP82279.1 - 2.2e-08 34.3 0.0 4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP82279.1 - 9.6e-08 31.9 0.1 3e-07 30.4 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP82279.1 - 7.7e-05 22.8 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP82279.1 - 9.9e-05 22.5 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP82279.1 - 0.0034 17.7 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 PRP82279.1 - 0.12 12.9 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GRAM PF02893.20 PRP82280.1 - 3.6e-05 23.6 0.0 0.00035 20.4 0.0 2.1 1 1 0 1 1 1 1 GRAM domain zf-MYND PF01753.18 PRP82281.1 - 1.1e-06 28.6 14.8 1.9e-06 27.9 14.8 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 PRP82281.1 - 0.0017 18.2 9.6 0.0017 18.2 9.6 1.7 2 0 0 2 2 2 1 HIT zinc finger zf-Mss51 PF13824.6 PRP82281.1 - 0.37 10.9 4.2 0.98 9.6 4.0 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Mito_carr PF00153.27 PRP82282.1 - 7.4e-47 157.2 0.3 2.3e-20 72.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein F_actin_bund_C PF18060.1 PRP82283.1 - 1.6e-09 37.7 12.5 1.6e-09 37.7 12.5 3.3 1 1 2 3 3 3 1 F actin bundling C terminal DP-EP PF08985.11 PRP82283.1 - 0.084 13.0 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 DP-EP family ApoO PF09769.9 PRP82283.1 - 3 7.8 5.1 1.7 8.6 0.3 2.4 2 1 0 2 2 2 0 Apolipoprotein O ALMT PF11744.8 PRP82283.1 - 4.8 5.9 12.7 7.7 5.2 12.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Lung_7-TM_R PF06814.13 PRP82284.1 - 3e-48 164.6 15.0 4.1e-48 164.1 15.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Ac76 PF05814.11 PRP82284.1 - 1.5 8.9 5.8 0.31 11.1 0.4 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) Fibrillarin_2 PF10113.9 PRP82285.1 - 0.31 9.6 1.2 0.76 8.3 0.2 1.9 1 1 1 2 2 2 0 Fibrillarin-like archaeal protein Dynamin_N PF00350.23 PRP82286.1 - 2.5e-29 102.5 0.1 2.5e-29 102.5 0.1 3.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 PRP82286.1 - 0.017 15.2 0.0 0.15 12.1 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase GrpE PF01025.19 PRP82286.1 - 5.9 6.5 9.5 1.1 8.9 0.1 3.0 3 0 0 3 3 3 0 GrpE IZUMO PF15005.6 PRP82286.1 - 9.5 6.7 6.7 2.5 8.6 0.1 3.0 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated WD40 PF00400.32 PRP82287.1 - 4.5e-13 49.5 18.9 1.8e-05 25.4 0.2 6.0 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82287.1 - 8.5e-11 42.0 0.0 4.5e-06 26.9 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 PRP82287.1 - 4.5e-06 26.5 0.7 0.057 13.4 0.2 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 PRP82287.1 - 0.0067 16.3 0.0 0.17 11.7 0.0 2.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PRP82287.1 - 0.0071 15.3 0.1 0.25 10.3 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TyrRSs_C PF16714.5 PRP82288.1 - 0.056 13.2 0.0 0.074 12.9 0.0 1.1 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain DNA_pol_A_exo1 PF01612.20 PRP82289.1 - 3.1e-10 40.1 0.0 8.3e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease Actin PF00022.19 PRP82290.1 - 5.3e-12 45.1 0.0 2.9e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 PRP82290.1 - 0.0019 17.5 0.1 0.0034 16.6 0.1 1.3 1 0 0 1 1 1 1 Putative actin-like family FtsA PF14450.6 PRP82290.1 - 0.029 14.8 0.0 0.13 12.7 0.0 1.9 2 1 0 2 2 2 0 Cell division protein FtsA IKKbetaNEMObind PF12179.8 PRP82290.1 - 0.21 11.7 0.7 0.73 9.9 0.0 2.0 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DHHC PF01529.20 PRP82291.1 - 1.6e-38 131.8 10.7 1.6e-38 131.8 10.7 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Spt4 PF06093.13 PRP82291.1 - 0.35 11.0 4.4 0.58 10.3 4.4 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger VPS13_C PF16909.5 PRP82292.1 - 3.6e-49 167.0 1.5 2.9e-46 157.5 0.1 3.1 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 PRP82292.1 - 5.5e-46 157.3 1.5 5.5e-46 157.3 1.5 4.4 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 PRP82292.1 - 4.3e-38 131.2 10.7 3.4e-31 108.6 0.2 4.5 5 0 0 5 5 5 3 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 PRP82292.1 - 3.5e-27 94.8 4.0 1.1e-26 93.2 0.0 4.0 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 PRP82292.1 - 2.1e-22 79.7 24.6 4e-12 46.1 1.8 6.2 6 1 0 6 6 6 3 Repeating coiled region of VPS13 ATG_C PF09333.11 PRP82292.1 - 5.9e-12 45.8 0.0 3.3e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain UPF0231 PF06062.11 PRP82292.1 - 0.19 12.0 1.3 5.2 7.4 0.3 3.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Ribosomal_L35p PF01632.19 PRP82293.1 - 0.0089 16.5 2.0 0.021 15.3 2.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L35 TMEM144 PF07857.12 PRP82294.1 - 5e-96 321.6 14.5 5.7e-96 321.4 14.5 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 PRP82294.1 - 3.6e-08 33.1 3.2 3.6e-08 33.1 3.2 2.6 2 2 0 2 2 2 2 Sugar transport protein Erg28 PF03694.13 PRP82294.1 - 0.016 15.5 0.4 0.1 13.0 0.4 2.3 1 1 0 1 1 1 0 Erg28 like protein Trp_oprn_chp PF09534.10 PRP82294.1 - 0.21 11.4 1.6 0.35 10.6 0.0 2.1 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ureide_permease PF07168.11 PRP82294.1 - 1.7 7.3 9.2 0.14 10.8 0.4 2.9 3 0 0 3 3 3 0 Ureide permease Ribosomal_L20 PF00453.18 PRP82295.1 - 1.8e-24 85.9 0.1 2.6e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L20 TraE PF05309.11 PRP82295.1 - 0.07 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 TraE protein HATPase_c PF02518.26 PRP82297.1 - 3.6e-27 95.1 0.1 8e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP82297.1 - 1.9e-22 79.5 2.8 1.2e-21 77.0 2.3 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 PRP82297.1 - 4.9e-13 48.9 0.6 2.9e-12 46.4 0.1 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 PRP82297.1 - 7.1e-09 35.9 0.0 1.6e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 PRP82297.1 - 2.7e-07 30.6 0.0 1.1e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold GAF PF01590.26 PRP82297.1 - 7.1e-07 29.9 0.0 7.8e-06 26.6 0.0 2.7 2 1 0 2 2 2 1 GAF domain PAS_3 PF08447.12 PRP82297.1 - 4.7e-06 26.8 0.1 1.1e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 PRP82297.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 PRP82297.1 - 0.07 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 PAS domain Sbt_1 PF05982.12 PRP82297.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Na+-dependent bicarbonate transporter superfamily PAS_12 PF18095.1 PRP82297.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain Y_phosphatase2 PF03162.13 PRP82298.1 - 2.1e-50 170.5 0.0 6.5e-50 168.9 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family Cytokin_check_N PF10407.9 PRP82298.1 - 2.3e-06 27.4 0.3 7.8e-06 25.8 0.3 2.0 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Abhydrolase_6 PF12697.7 PRP82299.1 - 4.1e-11 43.9 0.3 5.2e-11 43.6 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP82299.1 - 8.7e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0565 PF10561.9 PRP82299.1 - 0.0035 16.6 0.0 0.0042 16.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0565 RPGR1_C PF18111.1 PRP82300.1 - 1.2e-15 57.8 0.0 4.2e-15 56.0 0.0 2.1 1 0 0 1 1 1 1 Retinitis pigmentosa G-protein regulator interacting C-terminal DUF745 PF05335.13 PRP82300.1 - 0.00069 19.4 3.2 0.00069 19.4 3.2 5.7 5 1 2 7 7 7 1 Protein of unknown function (DUF745) SlyX PF04102.12 PRP82300.1 - 0.065 13.9 0.5 0.065 13.9 0.5 10.5 6 4 3 9 9 9 0 SlyX Amastin PF07344.11 PRP82301.1 - 6.5e-05 22.8 3.2 0.00013 21.9 3.0 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 PRP82301.1 - 0.11 12.3 4.0 0.42 10.5 4.1 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family FtsX PF02687.21 PRP82301.1 - 6.2 7.4 9.5 37 4.9 6.7 2.6 2 1 0 2 2 2 0 FtsX-like permease family Homeodomain PF00046.29 PRP82302.1 - 1.2e-22 79.4 6.5 5.5e-12 45.4 0.0 2.9 3 0 0 3 3 3 2 Homeodomain MADF_DNA_bdg PF10545.9 PRP82302.1 - 0.045 14.1 2.2 0.13 12.6 0.6 2.6 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Dor1 PF04124.12 PRP82303.1 - 2.2e-82 276.4 4.9 3.7e-82 275.7 4.9 1.4 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 PRP82303.1 - 4.5e-06 26.7 0.0 4.5e-06 26.7 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 FAM176 PF14851.6 PRP82303.1 - 0.021 14.5 9.1 0.057 13.1 9.1 1.8 1 0 0 1 1 1 0 FAM176 family BUD22 PF09073.10 PRP82303.1 - 0.071 12.4 17.6 0.14 11.5 17.6 1.4 1 0 0 1 1 1 0 BUD22 TMIE PF16038.5 PRP82303.1 - 0.083 12.7 3.7 0.2 11.5 3.7 1.6 1 0 0 1 1 1 0 TMIE protein AAA_23 PF13476.6 PRP82303.1 - 0.16 12.4 16.6 0.065 13.7 11.1 2.4 2 0 0 2 2 2 0 AAA domain Init_tRNA_PT PF04179.12 PRP82303.1 - 0.16 12.2 1.7 0.28 11.5 0.4 2.0 2 0 0 2 2 2 0 Rit1 DUSP-like domain Nucleoside_tran PF01733.18 PRP82303.1 - 1.8 7.9 5.4 3.4 7.0 3.7 2.0 2 0 0 2 2 2 0 Nucleoside transporter TRAP_alpha PF03896.16 PRP82303.1 - 5.1 6.2 9.6 8.7 5.5 9.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 PRP82303.1 - 6.9 6.6 17.3 13 5.7 17.3 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3908 PF13048.6 PRP82304.1 - 0.03 14.6 1.6 0.045 14.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3908) EF-G-binding_N PF07299.11 PRP82304.1 - 0.06 13.9 2.0 0.12 12.9 0.0 2.5 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal Dynamin_N PF00350.23 PRP82305.1 - 0.09 12.8 0.3 0.13 12.4 0.3 1.3 1 1 0 1 1 1 0 Dynamin family Ion_trans PF00520.31 PRP82306.1 - 7.3e-13 48.3 15.0 7.3e-13 48.3 15.0 2.8 2 1 0 2 2 2 1 Ion transport protein UCH PF00443.29 PRP82307.1 - 2.4e-76 256.6 0.0 3.3e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PRP82307.1 - 3e-19 69.4 0.0 1.8e-18 66.9 0.0 2.4 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 PRP82307.1 - 1.1e-16 61.3 0.0 5.8e-08 32.7 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 PRP82307.1 - 0.0003 20.5 0.2 0.29 10.9 0.0 2.7 2 0 0 2 2 2 2 Ubiquitin family Fascin PF06268.13 PRP82310.1 - 0.0016 18.6 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 Fascin domain DUF569 PF04601.13 PRP82310.1 - 0.012 15.2 0.1 0.044 13.5 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF569) MIP PF00230.20 PRP82311.1 - 2.7e-29 102.5 7.2 4e-29 101.9 7.2 1.2 1 0 0 1 1 1 1 Major intrinsic protein Kinesin PF00225.23 PRP82311.1 - 6.6e-11 41.7 4.1 7.2e-11 41.6 0.0 3.0 2 2 0 2 2 2 1 Kinesin motor domain AXIN1_TNKS_BD PF16646.5 PRP82311.1 - 0.05 14.5 1.2 0.13 13.3 0.0 2.3 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain GMC_oxred_N PF00732.19 PRP82312.1 - 6e-32 111.2 0.0 3.2e-31 108.8 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP82312.1 - 5.8e-13 49.6 0.0 1.1e-12 48.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PRP82312.1 - 8.2e-05 22.8 0.1 0.002 18.3 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP82312.1 - 0.0034 17.0 0.1 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP82312.1 - 0.052 12.8 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PRP82312.1 - 0.086 11.9 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 PRP82312.1 - 0.095 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein ApbA PF02558.16 PRP82312.1 - 0.18 11.4 0.1 0.41 10.3 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 PRP82312.1 - 0.19 10.8 0.2 0.27 10.3 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pectate_lyase_3 PF12708.7 PRP82313.1 - 9.3e-42 143.3 3.5 1.3e-34 119.9 1.0 5.5 4 1 0 4 4 4 3 Pectate lyase superfamily protein CelTOS PF18659.1 PRP82314.1 - 0.27 11.7 1.8 0.4 11.1 0.9 1.8 1 1 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites ZZ PF00569.17 PRP82315.1 - 2.4e-18 65.6 24.4 3.4e-11 42.8 7.6 2.3 2 0 0 2 2 2 2 Zinc finger, ZZ type PB1 PF00564.24 PRP82315.1 - 1.5e-13 50.4 0.1 1.5e-12 47.3 0.1 2.2 2 0 0 2 2 2 1 PB1 domain C1_2 PF03107.16 PRP82315.1 - 3.1e-06 27.4 18.9 7.9e-05 22.9 3.7 2.6 2 0 0 2 2 2 2 C1 domain HOIP-UBA PF16678.5 PRP82315.1 - 0.1 12.6 0.2 1.6 8.7 0.0 2.7 3 0 0 3 3 3 0 HOIP UBA domain pair SDA1 PF05285.12 PRP82315.1 - 0.17 11.3 3.8 2.1 7.7 0.1 2.0 2 0 0 2 2 2 0 SDA1 Radial_spoke PF04712.12 PRP82315.1 - 0.21 10.5 2.4 0.39 9.6 2.4 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein DUF2197 PF09963.9 PRP82315.1 - 0.41 10.9 7.1 3.2 8.1 1.0 2.8 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) C1_1 PF00130.22 PRP82315.1 - 1.1 9.2 18.9 1.3 9.0 5.2 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_Tyr PF07714.17 PRP82316.1 - 2.9e-41 141.5 0.0 5e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82316.1 - 2.2e-30 106.0 0.0 4.7e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP82316.1 - 4.6e-08 33.4 5.9 4.6e-08 33.4 5.9 2.6 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif LRR_8 PF13855.6 PRP82316.1 - 1.4e-06 27.9 13.4 0.023 14.4 1.9 5.4 4 1 0 4 4 4 2 Leucine rich repeat Kinase-like PF14531.6 PRP82316.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP82316.1 - 0.65 9.9 3.0 3.9 7.3 1.6 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Hydrolase_3 PF08282.12 PRP82316.1 - 2.7 7.7 6.3 4.4 7.0 2.7 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LRR_4 PF12799.7 PRP82316.1 - 2.7 8.5 26.3 2.3 8.8 3.1 6.9 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) Nup35_RRM_2 PF14605.6 PRP82319.1 - 1.5e-10 40.9 0.0 0.00035 20.5 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 PRP82319.1 - 2.5e-10 40.0 0.0 1.9e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 PRP82319.1 - 4.8e-05 23.3 0.1 0.51 10.3 0.0 2.9 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif PWI PF01480.17 PRP82319.1 - 0.00028 21.2 0.7 0.00061 20.0 0.0 2.0 2 0 0 2 2 2 1 PWI domain zf_CCCH_4 PF18345.1 PRP82319.1 - 0.019 15.0 0.5 0.05 13.7 0.5 1.8 1 0 0 1 1 1 0 Zinc finger domain DUF1866 PF08952.11 PRP82319.1 - 0.026 14.4 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF1110 PF06533.12 PRP82319.1 - 0.17 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) N_BRCA1_IG PF16158.5 PRP82320.1 - 2.1e-27 95.8 0.1 3.9e-27 95.0 0.1 1.5 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 PRP82320.1 - 6.6e-14 51.6 0.1 1.3e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 PB1 domain Ubiquitin_2 PF14560.6 PRP82320.1 - 0.035 14.5 0.1 0.074 13.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_e1_thiolCys PF10585.9 PRP82322.1 - 1.3e-85 287.4 5.4 1.3e-85 287.4 5.4 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site ThiF PF00899.21 PRP82322.1 - 6.5e-79 264.7 0.0 3.5e-67 226.3 0.0 2.2 2 0 0 2 2 2 2 ThiF family E1_UFD PF09358.10 PRP82322.1 - 1.5e-30 105.7 0.1 4.1e-30 104.3 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 PRP82322.1 - 8.2e-30 102.8 0.3 1.9e-29 101.7 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 PRP82322.1 - 2.5e-23 82.1 1.3 2.5e-23 82.1 1.3 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle PAZ PF02170.22 PRP82322.1 - 0.029 14.2 0.1 0.16 11.8 0.0 2.3 3 0 0 3 3 3 0 PAZ domain RNA_pol_Rpb2_6 PF00562.28 PRP82322.1 - 0.061 12.4 0.1 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Ank_2 PF12796.7 PRP82323.1 - 8.8e-50 167.2 0.0 3.5e-10 40.3 0.0 6.4 2 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP82323.1 - 3.6e-32 110.0 4.4 0.0016 18.7 0.0 12.8 6 3 8 14 14 14 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP82323.1 - 3.4e-31 107.2 5.5 2.4e-05 24.8 0.0 9.0 4 3 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82323.1 - 3.6e-17 60.7 0.8 0.67 10.7 0.0 11.7 14 0 0 14 14 14 3 Ankyrin repeat Ank PF00023.30 PRP82323.1 - 4.8e-17 61.6 7.3 0.059 13.8 0.1 12.0 12 2 1 13 13 12 2 Ankyrin repeat YlzJ PF14035.6 PRP82323.1 - 5.7e-05 23.2 0.1 11 6.3 0.0 5.1 5 0 0 5 5 5 1 YlzJ-like protein ADSL_C PF10397.9 PRP82323.1 - 0.0073 16.8 2.2 1.6e+02 2.9 0.0 6.6 3 3 2 5 5 5 0 Adenylosuccinate lyase C-terminus DUF5062 PF16691.5 PRP82323.1 - 0.01 16.0 0.9 1.8e+02 2.3 0.0 5.6 4 2 1 6 6 6 0 Domain of unknown function (DUF5062) DUF5076 PF16826.5 PRP82323.1 - 0.039 13.9 0.8 0.19 11.7 0.2 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF5076) Anthrax_toxA PF03497.16 PRP82323.1 - 0.071 13.2 0.6 27 4.8 0.0 3.8 3 1 2 5 5 5 0 Anthrax toxin LF subunit Ub-RnfH PF03658.14 PRP82323.1 - 0.11 12.9 0.2 51 4.3 0.0 3.7 3 0 0 3 3 3 0 RnfH family Ubiquitin Acetyltransf_17 PF17668.1 PRP82323.1 - 0.11 13.3 3.5 16 6.3 0.0 5.6 2 2 3 6 6 6 0 Acetyltransferase (GNAT) domain Hairy_orange PF07527.13 PRP82323.1 - 0.43 10.8 5.4 84 3.5 0.0 6.2 7 0 0 7 7 7 0 Hairy Orange TFIID-18kDa PF02269.16 PRP82324.1 - 0.0077 16.2 0.0 0.36 10.9 0.0 2.8 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit AbiEi_1 PF09407.10 PRP82324.1 - 0.15 12.4 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AbiEi antitoxin C-terminal domain DUF445 PF04286.12 PRP82324.1 - 0.16 11.8 1.0 0.25 11.1 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Pkinase PF00069.25 PRP82325.1 - 6.4e-58 196.2 0.0 1e-57 195.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82325.1 - 3.7e-38 131.3 0.1 1.6e-33 116.1 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP82325.1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP82325.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP82325.1 - 0.0048 16.3 0.0 0.013 14.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP82325.1 - 0.067 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PRP82325.1 - 0.12 12.3 0.0 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 PRP82326.1 - 9.2e-11 42.1 0.5 0.75 10.8 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat PHD PF00628.29 PRP82326.1 - 1.4e-09 37.7 8.1 3.7e-09 36.3 8.1 1.7 1 0 0 1 1 1 1 PHD-finger ANAPC4_WD40 PF12894.7 PRP82326.1 - 6e-05 23.3 0.1 2.6 8.4 0.0 4.5 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PHD_2 PF13831.6 PRP82326.1 - 0.0003 20.3 3.5 0.00074 19.0 3.5 1.7 1 0 0 1 1 1 1 PHD-finger Rubredoxin PF00301.20 PRP82326.1 - 0.0088 16.0 0.1 0.039 14.0 0.1 2.1 1 0 0 1 1 1 1 Rubredoxin Nucleoporin_N PF08801.11 PRP82326.1 - 0.11 11.2 0.1 4.4 5.9 0.0 2.8 3 1 0 3 3 3 0 Nup133 N terminal like PHD_4 PF16866.5 PRP82326.1 - 0.54 10.4 5.8 1.5 8.9 5.8 1.8 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 PRP82326.1 - 7.8 6.9 11.0 0.61 10.4 3.5 2.7 3 0 0 3 3 3 0 C1 domain Ank_2 PF12796.7 PRP82327.1 - 5.6e-56 187.1 0.0 5.6e-10 39.7 0.0 6.2 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82327.1 - 7.6e-35 118.9 7.3 1e-05 26.0 0.6 8.9 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82327.1 - 8.3e-25 86.5 9.0 0.0084 16.4 0.0 11.6 4 4 9 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82327.1 - 2.8e-23 79.5 0.5 0.44 11.2 0.0 11.9 12 1 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 PRP82327.1 - 3e-23 81.2 1.7 0.056 13.9 0.0 11.8 11 1 1 12 12 12 4 Ankyrin repeat Secretogranin_V PF05281.11 PRP82327.1 - 0.0026 17.4 0.1 16 5.0 0.0 3.9 4 0 0 4 4 4 1 Neuroendocrine protein 7B2 precursor (Secretogranin V) DUF4671 PF15710.5 PRP82327.1 - 0.069 12.0 0.4 8.2 5.1 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4671) Hairy_orange PF07527.13 PRP82327.1 - 0.14 12.4 4.4 1.9e+02 2.4 0.0 6.6 8 0 0 8 8 8 0 Hairy Orange Pex14_N PF04695.13 PRP82327.1 - 0.21 12.2 1.9 32 5.1 0.0 3.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ank_2 PF12796.7 PRP82328.1 - 1.5e-14 54.3 0.0 2.1e-06 28.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82328.1 - 6.3e-08 33.0 0.1 0.19 12.4 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82328.1 - 5.5e-07 29.8 0.9 0.012 15.9 0.0 5.0 4 2 2 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP82328.1 - 2.1e-05 24.8 0.6 1.6 9.3 0.0 5.4 6 0 0 6 6 6 1 Ankyrin repeat Ank_3 PF13606.6 PRP82328.1 - 0.00041 20.6 0.0 2.1 9.2 0.0 4.7 6 0 0 6 6 6 1 Ankyrin repeat Pkinase_Tyr PF07714.17 PRP82329.1 - 2.4e-79 266.3 0.0 3.4e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82329.1 - 2.4e-49 168.1 0.0 3.7e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EphA2_TM PF14575.6 PRP82329.1 - 0.0081 17.0 0.0 0.021 15.7 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 PRP82329.1 - 0.04 13.7 0.8 0.096 12.5 0.8 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FtsK_alpha PF17854.1 PRP82329.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 FtsK alpha domain TMEM154 PF15102.6 PRP82329.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.4 2 1 1 3 3 3 0 TMEM154 protein family SKG6 PF08693.10 PRP82329.1 - 1 8.8 6.7 3.5 7.1 6.7 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase_fungal PF17667.1 PRP82329.1 - 2.6 6.7 6.6 0.11 11.2 0.2 1.8 2 0 0 2 2 2 0 Fungal protein kinase TFIIA PF03153.13 PRP82329.1 - 5.1 7.0 9.5 8.2 6.3 9.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dpy-30 PF05186.13 PRP82331.1 - 1.3e-09 37.6 0.3 2.4e-09 36.7 0.3 1.5 1 0 0 1 1 1 1 Dpy-30 motif OSTbeta PF15048.6 PRP82331.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.6 2 1 0 2 2 2 0 Organic solute transporter subunit beta protein UCH_1 PF13423.6 PRP82332.1 - 7.1e-77 259.1 6.1 1e-76 258.6 6.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 PRP82332.1 - 7.1e-19 68.9 0.0 1.3e-18 68.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 PRP82332.1 - 1e-11 44.8 7.2 3e-08 33.5 2.7 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase WD40_like PF17005.5 PRP82332.1 - 0.0017 17.7 0.2 0.049 12.9 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain Peptidase_C1 PF00112.23 PRP82333.1 - 2.3e-29 103.0 7.8 8.3e-19 68.5 0.5 2.4 2 1 1 3 3 3 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP82333.1 - 2.9e-12 46.8 0.8 4.7e-12 46.1 0.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP82333.1 - 8.6e-08 31.4 0.4 1.5e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 Peptidase C1-like family Styelin PF17562.2 PRP82333.1 - 0.016 15.5 0.1 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 Styelin SinI PF08671.10 PRP82333.1 - 0.026 14.3 3.8 2.3 8.1 0.2 2.5 2 0 0 2 2 2 0 Anti-repressor SinI S_100 PF01023.19 PRP82333.1 - 1.4 8.7 3.6 27 4.6 0.1 2.5 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain RMI1_N PF08585.12 PRP82335.1 - 2.7e-09 37.1 0.0 2e-05 24.4 0.0 3.7 2 2 1 3 3 3 2 RecQ mediated genome instability protein UBA_e1_thiolCys PF10585.9 PRP82335.1 - 0.0065 16.4 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Pkinase PF00069.25 PRP82336.1 - 4.1e-78 262.4 0.0 5.9e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82336.1 - 1.2e-34 119.8 0.0 1.6e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP82336.1 - 7.2e-08 32.1 0.2 5.4e-07 29.2 0.0 2.2 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 PRP82336.1 - 3e-05 23.5 0.1 5.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP82336.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP82336.1 - 0.04 12.7 0.0 0.13 11.0 0.0 1.6 1 1 0 1 1 1 0 Fungal protein kinase Zn_clus PF00172.18 PRP82338.1 - 1.7e-06 28.0 9.5 1.7e-06 28.0 9.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain START PF01852.19 PRP82339.1 - 0.048 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 START domain NAD_binding_10 PF13460.6 PRP82340.1 - 0.00024 21.1 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PRP82340.1 - 0.035 13.3 0.0 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.19 PRP82340.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.22 PRP82341.1 - 3.9e-54 182.6 0.0 5.1e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP82341.1 - 3.1e-22 79.0 0.0 5.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP82341.1 - 2.8e-10 39.9 0.0 4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP82341.1 - 5.4e-05 22.8 0.6 0.00055 19.5 0.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP82341.1 - 0.00028 20.9 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP82341.1 - 0.0044 16.9 0.0 0.5 10.3 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 PRP82341.1 - 0.021 14.2 0.1 0.03 13.7 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AIG1 PF04548.16 PRP82341.1 - 0.035 13.4 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family FGGY_N PF00370.21 PRP82342.1 - 1.7e-20 73.6 0.0 2.6e-14 53.4 0.0 3.0 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PRP82342.1 - 6.5e-20 71.7 0.0 1.4e-19 70.6 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain AnmK PF03702.14 PRP82342.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Anhydro-N-acetylmuramic acid kinase Peptidase_C78 PF07910.13 PRP82343.1 - 7.1e-50 169.4 0.0 1.2e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 zf-RanBP PF00641.18 PRP82343.1 - 6e-08 31.9 1.2 1.8e-07 30.4 1.2 1.9 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Ank_5 PF13857.6 PRP82344.1 - 3.1e-22 78.4 0.0 0.024 15.0 0.0 7.4 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP82344.1 - 4.5e-22 78.4 0.0 1.3e-09 38.5 0.0 3.7 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82344.1 - 4.6e-20 71.7 0.0 1.8e-06 28.4 0.1 5.9 2 1 5 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP82344.1 - 2.2e-14 53.2 0.0 0.81 10.2 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 PRP82344.1 - 2.5e-12 45.8 0.0 5.3 7.9 0.0 7.9 8 0 0 8 8 8 3 Ankyrin repeat YlzJ PF14035.6 PRP82344.1 - 5.8e-05 23.2 0.3 13 6.0 0.0 5.4 6 0 0 6 6 6 1 YlzJ-like protein Hairy_orange PF07527.13 PRP82344.1 - 0.49 10.6 2.9 3.4e+02 1.5 0.0 5.3 7 0 0 7 7 7 0 Hairy Orange DUF4242 PF14026.6 PRP82344.1 - 2.9 8.1 4.2 68 3.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4242) Med16 PF11635.8 PRP82346.1 - 0.14 10.1 0.9 0.14 10.1 0.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 16 Ank_2 PF12796.7 PRP82347.1 - 4.7e-40 136.0 0.2 8.7e-07 29.4 0.0 6.2 3 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82347.1 - 2.2e-32 111.0 10.2 1.6e-06 28.5 0.2 10.0 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82347.1 - 1.2e-21 76.5 9.4 0.01 16.1 0.0 10.0 4 4 6 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82347.1 - 2.4e-18 64.3 2.1 2.5 8.9 0.0 11.7 15 0 0 15 15 15 5 Ankyrin repeat Ank PF00023.30 PRP82347.1 - 2.7e-15 56.0 10.0 1.2 9.7 0.0 13.3 15 0 0 15 15 15 2 Ankyrin repeat G-alpha PF00503.20 PRP82350.1 - 6e-86 288.8 0.2 1.2e-85 287.8 0.2 1.5 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PRP82350.1 - 4e-08 32.9 0.1 1.2e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP82350.1 - 0.014 14.7 0.4 3.1 7.1 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Arm PF00514.23 PRP82351.1 - 2.2e-36 122.8 14.2 1.1e-09 38.0 0.0 8.4 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PRP82351.1 - 1e-17 62.7 11.6 0.0015 18.6 0.0 8.6 9 0 0 9 9 9 5 HEAT repeat Cnd1 PF12717.7 PRP82351.1 - 2e-17 63.7 0.0 0.00072 19.6 0.0 4.2 1 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PRP82351.1 - 4.3e-17 62.2 11.6 0.0015 19.0 0.1 6.7 6 1 1 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 PRP82351.1 - 8.6e-17 61.3 13.3 0.00038 20.8 0.1 5.2 3 2 2 5 5 5 5 HEAT repeats DNA_alkylation PF08713.11 PRP82351.1 - 2e-09 37.5 0.0 0.03 14.1 0.0 3.8 1 1 2 3 3 3 3 DNA alkylation repair enzyme Adaptin_N PF01602.20 PRP82351.1 - 4.2e-06 25.6 3.0 0.0077 14.8 0.4 3.3 1 1 1 2 2 2 2 Adaptin N terminal region Proteasom_PSMB PF10508.9 PRP82351.1 - 4.8e-06 25.4 0.2 0.00026 19.6 0.1 2.5 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit CLASP_N PF12348.8 PRP82351.1 - 0.00017 21.3 0.2 1.8 8.1 0.0 3.7 2 1 1 3 3 3 2 CLASP N terminal API5 PF05918.11 PRP82351.1 - 0.00062 18.7 0.4 1.3 7.8 0.0 3.5 1 1 2 3 3 3 2 Apoptosis inhibitory protein 5 (API5) CHASE6_C PF17150.4 PRP82351.1 - 0.00084 20.0 0.1 3.1 8.5 0.0 4.7 4 1 0 4 4 4 1 C-terminal domain of two-partite extracellular sensor domain Arm_2 PF04826.13 PRP82351.1 - 0.0019 17.7 0.1 0.7 9.3 0.0 3.3 3 1 1 4 4 4 1 Armadillo-like DUF3361 PF11841.8 PRP82351.1 - 0.0035 17.3 0.2 2.6 8.0 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) RICTOR_V PF14668.6 PRP82351.1 - 0.018 15.2 0.0 3.5 7.9 0.0 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 PRP82351.1 - 0.047 14.4 12.5 2.5 9.0 0.1 5.9 6 1 0 6 6 5 0 PBS lyase HEAT-like repeat XPG_N PF00752.17 PRP82352.1 - 3.6e-31 107.6 0.0 8.5e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 PRP82352.1 - 1.6e-29 102.1 0.0 3.6e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 PRP82352.1 - 1.2e-05 25.8 0.0 4.2e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 PRP82352.1 - 0.026 15.1 0.0 0.094 13.3 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4142 PF13628.6 PRP82352.1 - 0.12 12.6 3.0 0.22 11.7 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Ank_2 PF12796.7 PRP82353.1 - 6.1e-19 68.4 0.0 4e-11 43.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82353.1 - 3.8e-16 59.2 1.0 5.9e-09 36.3 0.1 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82353.1 - 1.1e-12 47.0 0.6 0.048 14.2 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PRP82353.1 - 2.9e-11 43.3 0.3 0.0045 17.4 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PRP82353.1 - 5.2e-10 39.4 0.5 0.045 14.1 0.1 4.7 3 1 3 6 6 6 3 Ankyrin repeats (many copies) F-box PF00646.33 PRP82353.1 - 0.078 12.9 0.3 0.27 11.2 0.3 1.9 1 0 0 1 1 1 0 F-box domain Ank_2 PF12796.7 PRP82354.1 - 6.2e-11 42.7 0.0 8.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82354.1 - 3e-06 27.7 0.1 0.0006 20.3 0.1 2.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82354.1 - 0.00012 22.2 0.0 1.5 9.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP82354.1 - 0.00029 21.1 0.1 0.18 12.1 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP82354.1 - 0.00033 21.0 0.2 0.67 10.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP82355.1 - 0.057 13.7 0.1 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Cytomega_TRL10 PF06084.11 PRP82355.1 - 0.098 12.7 0.2 0.098 12.7 0.2 1.0 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Ank_2 PF12796.7 PRP82356.1 - 3.1e-53 178.3 0.0 4.1e-09 36.9 0.0 6.5 4 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82356.1 - 8.2e-45 150.6 0.4 3.2e-05 24.4 0.1 10.4 6 3 4 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82356.1 - 6.4e-30 102.8 1.0 0.00014 22.1 0.0 12.8 6 4 8 14 14 14 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82356.1 - 2.7e-26 88.7 0.0 1.7 9.5 0.0 14.6 15 0 0 15 15 15 5 Ankyrin repeat Ank PF00023.30 PRP82356.1 - 2.5e-25 87.7 5.7 0.4 11.2 0.0 14.9 14 3 0 14 14 14 7 Ankyrin repeat DUF3734 PF12536.8 PRP82356.1 - 0.01 16.1 2.8 49 4.3 0.0 5.4 4 2 2 6 6 6 0 Patatin phospholipase DUF1612 PF07756.12 PRP82356.1 - 0.069 13.4 2.6 49 4.2 0.1 5.0 4 1 1 5 5 5 0 Protein of unknown function (DUF1612) RhoGEF PF00621.20 PRP82358.1 - 5.3e-40 137.6 7.8 1.2e-39 136.4 7.8 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PRP82358.1 - 7.7e-07 29.6 0.0 5.3e-06 26.9 0.0 2.5 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 PRP82358.1 - 0.0048 16.9 0.0 0.045 13.7 0.0 2.6 2 0 0 2 2 2 1 PH domain Ank_2 PF12796.7 PRP82359.1 - 3.3e-27 94.9 0.0 4.2e-07 30.5 0.0 5.9 4 1 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82359.1 - 3.4e-26 91.3 0.0 0.001 19.6 0.0 7.5 4 2 3 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82359.1 - 1.2e-15 57.4 0.2 0.051 13.9 0.0 8.7 5 1 4 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82359.1 - 2e-10 40.0 0.0 5.2 8.0 0.0 8.8 10 0 0 10 10 10 1 Ankyrin repeat Ank PF00023.30 PRP82359.1 - 9.6e-10 38.5 5.7 6.1 7.5 0.0 9.5 9 1 1 10 10 10 1 Ankyrin repeat YlzJ PF14035.6 PRP82359.1 - 2.4e-05 24.5 0.1 4.1 7.7 0.0 4.6 5 0 0 5 5 5 2 YlzJ-like protein DUF1731 PF08338.11 PRP82359.1 - 0.11 12.4 1.2 1.1 9.1 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1731) Ank_2 PF12796.7 PRP82360.1 - 4.6e-85 280.3 0.3 3.9e-12 46.6 0.1 8.3 3 3 6 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82360.1 - 3e-53 177.6 15.1 6.2e-08 33.0 0.1 12.9 5 5 10 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82360.1 - 5.3e-34 112.4 2.1 0.68 10.7 0.0 15.6 17 0 0 17 17 17 9 Ankyrin repeat Ank_5 PF13857.6 PRP82360.1 - 1.8e-33 114.2 18.4 0.057 13.7 0.1 17.1 5 3 13 18 18 18 10 Ankyrin repeats (many copies) Ank PF00023.30 PRP82360.1 - 3.3e-32 109.5 13.7 0.016 15.7 0.0 16.8 18 2 1 19 19 19 7 Ankyrin repeat EBV-NA1 PF02905.14 PRP82360.1 - 0.2 11.4 0.0 68 3.3 0.0 3.5 3 1 0 3 3 3 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain DUF2277 PF10041.9 PRP82360.1 - 0.37 11.1 4.2 43 4.5 0.1 4.5 2 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) VapB_antitoxin PF09957.9 PRP82360.1 - 0.53 10.3 6.3 1.1e+02 2.9 0.0 6.0 7 0 0 7 7 7 0 Bacterial antitoxin of type II TA system, VapB URO-D PF01208.17 PRP82362.1 - 3.8e-133 443.9 0.0 4.3e-133 443.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) ABC_tran PF00005.27 PRP82363.1 - 2.6e-29 102.5 0.0 4.6e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP82363.1 - 5.9e-14 51.9 20.7 9.4e-14 51.3 20.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP82363.1 - 1.6e-12 47.8 0.0 1.6e-08 34.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PRP82363.1 - 0.0015 18.0 0.1 0.27 10.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 PRP82363.1 - 0.002 17.9 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_15 PF13175.6 PRP82363.1 - 0.0057 16.4 0.1 0.42 10.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 PRP82363.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 PRP82363.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP82363.1 - 0.14 12.6 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain GST_N_2 PF13409.6 PRP82364.1 - 8.4e-09 35.6 0.0 1.5e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP82364.1 - 1.3e-07 31.9 0.1 3e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP82364.1 - 0.013 15.7 0.0 0.032 14.4 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP82364.1 - 0.02 15.2 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ank_2 PF12796.7 PRP82366.1 - 1.2e-30 105.9 0.1 4.9e-09 36.7 0.1 5.4 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82366.1 - 6.5e-23 80.8 9.7 0.00035 21.1 0.1 7.9 5 2 4 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82366.1 - 8.2e-18 64.2 7.2 0.23 11.8 0.0 10.8 4 3 7 11 11 11 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP82366.1 - 1.2e-13 50.8 4.5 2.1 9.0 0.0 9.5 9 1 1 10 10 10 4 Ankyrin repeat Ank_3 PF13606.6 PRP82366.1 - 1.3e-13 49.7 4.3 10 7.1 0.0 9.9 8 1 1 9 9 9 2 Ankyrin repeat F-box-like PF12937.7 PRP82367.1 - 5.6e-10 39.0 0.6 1.3e-09 37.8 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP82367.1 - 9.4e-08 31.8 1.4 2.3e-07 30.5 1.4 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 PRP82367.1 - 0.038 14.5 0.3 0.064 13.8 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Jas PF16135.5 PRP82370.1 - 4.2e-09 36.5 1.3 4.2e-09 36.5 1.3 2.0 2 0 0 2 2 2 1 TPL-binding domain in jasmonate signalling c-SKI_SMAD_bind PF08782.10 PRP82370.1 - 0.073 13.3 0.2 0.15 12.3 0.2 1.6 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Chromo PF00385.24 PRP82370.1 - 0.28 11.1 0.0 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain FancD2 PF14631.6 PRP82370.1 - 0.32 8.3 1.7 0.41 8.0 1.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Pap_E4 PF02711.14 PRP82370.1 - 1.1 10.3 8.0 1.1 10.2 4.6 2.3 2 0 0 2 2 2 0 E4 protein Pox_Ag35 PF03286.14 PRP82370.1 - 7 6.4 19.2 1.3 8.8 15.6 1.7 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Hydantoinase_B PF02538.14 PRP82371.1 - 3.5e-208 692.2 1.9 4.5e-208 691.8 1.9 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 PRP82371.1 - 1.1e-102 343.2 0.9 2.4e-102 342.1 0.0 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 PRP82371.1 - 1.2e-55 188.0 1.5 6.7e-54 182.3 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DIT1_PvcA PF05141.12 PRP82372.1 - 2.2e-72 243.8 0.0 1.2e-42 146.3 0.0 2.1 1 1 1 2 2 2 2 Pyoverdine/dityrosine biosynthesis protein Amidohydro_1 PF01979.20 PRP82373.1 - 1.6e-22 80.3 0.1 4e-14 52.7 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.11 PRP82373.1 - 1.7e-18 67.4 0.0 8.3e-08 32.1 0.0 3.4 3 0 0 3 3 3 3 Amidohydrolase family Thiolase_N PF00108.23 PRP82377.1 - 1.9e-18 66.8 1.3 1.5e-16 60.6 0.5 2.4 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PRP82377.1 - 3.4e-11 42.9 0.2 2.9e-10 39.8 0.1 2.4 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 PRP82377.1 - 0.00011 22.0 0.8 0.0069 16.2 0.3 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 PRP82377.1 - 0.00016 21.4 3.2 0.0082 15.7 1.0 2.3 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 PRP82377.1 - 0.0012 17.7 0.3 0.044 12.5 0.1 2.2 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 PRP82377.1 - 0.0067 16.4 0.2 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Pkinase_Tyr PF07714.17 PRP82378.1 - 3.3e-66 223.2 0.0 2.6e-65 220.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82378.1 - 8.1e-48 163.1 0.3 3.5e-46 157.7 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 PRP82378.1 - 2.8e-40 135.9 116.9 9.7e-08 31.7 6.7 16.4 8 3 10 19 19 19 14 Leucine rich repeat LRR_4 PF12799.7 PRP82378.1 - 1.8e-30 104.5 112.9 0.0024 18.2 0.1 19.6 11 4 7 20 20 19 14 Leucine Rich repeats (2 copies) EF-hand_1 PF00036.32 PRP82378.1 - 2.3e-12 45.5 0.6 6.4e-05 22.2 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PRP82378.1 - 7.2e-11 42.4 0.1 7.2e-11 42.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP82378.1 - 1.8e-10 39.9 1.7 0.00022 20.9 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PRP82378.1 - 7.8e-09 35.3 0.2 9.3e-08 31.8 0.0 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP82378.1 - 5.3e-06 25.7 3.5 0.001 18.5 0.2 2.8 2 0 0 2 2 2 2 EF hand LRR_6 PF13516.6 PRP82378.1 - 1.3e-05 24.9 96.3 3.4 8.0 0.1 22.7 25 0 0 25 25 25 4 Leucine Rich repeat Kdo PF06293.14 PRP82378.1 - 0.013 14.9 0.0 0.034 13.5 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_1 PF00560.33 PRP82378.1 - 0.084 13.5 105.7 1.8 9.4 0.2 26.3 26 4 1 27 27 26 0 Leucine Rich Repeat EF-hand_9 PF14658.6 PRP82378.1 - 0.096 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain DUF131 PF01998.17 PRP82378.1 - 0.31 10.7 2.3 42 3.9 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF131 LRR_5 PF13306.6 PRP82378.1 - 0.48 10.4 7.8 4.7 7.2 0.1 4.6 4 0 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) LPP PF04728.13 PRP82378.1 - 0.51 10.8 5.7 26 5.3 0.0 4.5 4 0 0 4 4 4 0 Lipoprotein leucine-zipper THP2 PF09432.10 PRP82378.1 - 2.7 8.1 14.4 0.041 13.9 4.5 2.9 2 1 1 3 3 3 0 Tho complex subunit THP2 LZ_Tnp_IS66 PF13007.7 PRP82378.1 - 3.7 8.4 7.5 14 6.5 7.5 2.1 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain RasGAP PF00616.19 PRP82379.1 - 2.4e-56 190.7 2.7 3e-56 190.4 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 PRP82379.1 - 5.6e-22 78.4 6.7 5.6e-22 78.4 6.7 2.7 3 0 0 3 3 3 1 RasGAP C-terminus DUF4050 PF13259.6 PRP82380.1 - 4.8e-08 33.5 0.2 0.0007 20.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) adh_short PF00106.25 PRP82383.1 - 1.7e-43 148.4 0.0 2.2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP82383.1 - 1.2e-31 110.1 0.0 1.6e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP82383.1 - 9e-10 38.8 0.1 1.3e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PRP82383.1 - 3.6e-09 36.4 0.0 6e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 PRP82383.1 - 1.9e-05 24.3 0.1 3e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PRP82383.1 - 3.1e-05 23.6 0.3 0.00013 21.5 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP82383.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Pyr_excise PF03013.14 PRP82383.1 - 0.036 14.1 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase RmlD_sub_bind PF04321.17 PRP82383.1 - 0.042 12.9 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.15 PRP82383.1 - 0.067 13.4 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ATG27 PF09451.10 PRP82385.1 - 5.7e-11 42.8 0.0 7.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 PRP82385.1 - 1.1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat DUF4690 PF15756.5 PRP82385.1 - 0.084 13.5 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Man-6-P_recep PF02157.15 PRP82385.1 - 0.14 11.2 0.5 0.21 10.7 0.5 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Acyl-CoA_dh_1 PF00441.24 PRP82386.1 - 3.7e-32 111.6 1.6 5e-32 111.2 1.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 PRP82386.1 - 6.8e-18 64.6 0.5 1.5e-17 63.5 0.5 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 PRP82386.1 - 3.3e-13 49.7 0.1 7.2e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PRP82386.1 - 3.2e-07 31.0 0.0 1.2e-06 29.2 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PRP82386.1 - 0.0005 20.3 0.7 0.00082 19.6 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2501 PF10696.9 PRP82386.1 - 0.17 12.2 0.0 4.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2501) SET PF00856.28 PRP82387.1 - 6.8e-17 62.4 0.4 1.4e-16 61.4 0.4 1.5 1 1 0 1 1 1 1 SET domain NHS PF15273.6 PRP82387.1 - 0.00011 21.5 1.2 0.001 18.3 0.0 2.0 1 1 1 2 2 2 2 NHS-like Vps16_C PF04840.12 PRP82388.1 - 0.0052 15.9 0.1 0.011 14.8 0.1 1.5 1 0 0 1 1 1 1 Vps16, C-terminal region 4HBT PF03061.22 PRP82389.1 - 3.1e-06 27.4 0.0 1.8e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Thioesterase superfamily DUF4413 PF14372.6 PRP82389.1 - 0.054 13.9 0.6 0.1 13.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) DUF812 PF05667.11 PRP82390.1 - 3.1e-128 429.3 19.2 4.1e-128 428.9 19.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Ribosomal_S8e PF01201.22 PRP82390.1 - 0.34 11.1 1.9 0.61 10.3 1.9 1.5 1 0 0 1 1 1 0 Ribosomal protein S8e Baculo_PEP_C PF04513.12 PRP82390.1 - 2.4 8.2 12.6 5.2 7.1 0.2 3.6 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus UbiA PF01040.18 PRP82391.1 - 1.5e-46 158.7 7.2 2.2e-46 158.2 7.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PARP PF00644.20 PRP82392.1 - 4.5e-44 150.4 0.3 1.3e-43 148.9 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PRP82392.1 - 5.6e-23 81.5 0.6 2.5e-22 79.5 0.1 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain Ank_2 PF12796.7 PRP82392.1 - 3.1e-18 66.1 5.8 0.00041 20.9 0.0 6.0 6 1 0 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82392.1 - 3.1e-15 56.3 5.0 0.011 16.3 0.0 8.2 6 2 1 8 8 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP82392.1 - 1e-13 51.2 3.7 0.0022 18.3 0.0 6.3 6 2 2 8 8 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82392.1 - 2.7e-07 30.4 8.7 3.2 8.6 0.0 7.8 8 0 0 8 8 6 3 Ankyrin repeat BRCT PF00533.26 PRP82392.1 - 1.6e-06 28.4 0.0 5.2e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP82392.1 - 8.6e-05 22.9 0.0 0.00036 20.9 0.0 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Ank PF00023.30 PRP82392.1 - 0.00012 22.4 9.6 0.074 13.5 0.0 6.7 7 0 0 7 7 7 1 Ankyrin repeat SAP PF02037.27 PRP82392.1 - 0.0044 16.7 0.8 0.0044 16.7 0.8 3.0 3 0 0 3 3 3 1 SAP domain PTCB-BRCT PF12738.7 PRP82392.1 - 0.006 16.5 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 twin BRCT domain YqhG PF11079.8 PRP82392.1 - 0.043 12.8 2.8 0.15 11.0 2.8 1.9 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function NapD PF03927.13 PRP82392.1 - 0.062 13.4 0.3 0.18 11.9 0.0 1.9 2 0 0 2 2 1 0 NapD protein DDHD PF02862.17 PRP82392.1 - 0.14 12.3 1.9 3.9 7.6 0.3 2.8 2 0 0 2 2 2 0 DDHD domain Phage_CI_repr PF07022.13 PRP82392.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Fzo_mitofusin PF04799.13 PRP82392.1 - 4 7.0 6.6 1.1 8.8 1.4 2.5 2 0 0 2 2 2 0 fzo-like conserved region LCAT PF02450.15 PRP82393.1 - 1.9e-37 129.4 0.2 4.1e-37 128.3 0.2 1.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 PRP82393.1 - 5e-06 26.2 0.0 7.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 PRP82393.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) His_Phos_1 PF00300.22 PRP82393.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Lipase_2 PF01674.18 PRP82393.1 - 0.057 12.9 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) PGAP1 PF07819.13 PRP82393.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein GlutR_dimer PF00745.20 PRP82393.1 - 0.081 13.4 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF726 PF05277.12 PRP82393.1 - 0.095 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Hydrolase_4 PF12146.8 PRP82393.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Kelch_4 PF13418.6 PRP82394.1 - 0.0071 16.3 1.1 0.31 11.1 0.0 3.2 3 1 1 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP82394.1 - 0.014 15.4 0.1 0.066 13.2 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Kelch_5 PF13854.6 PRP82394.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_6 PF13964.6 PRP82394.1 - 0.092 13.1 0.2 0.94 9.9 0.0 2.7 3 0 0 3 3 3 0 Kelch motif Kelch_1 PF01344.25 PRP82394.1 - 0.14 11.8 1.5 1.2 8.7 1.5 2.4 1 1 0 1 1 1 0 Kelch motif LPG_synthase_TM PF03706.13 PRP82394.1 - 0.57 9.7 12.2 0.51 9.8 6.2 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region DKCLD PF08068.12 PRP82395.1 - 3.4e-31 107.1 0.2 8.9e-30 102.5 0.3 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 PRP82395.1 - 3.1e-22 79.6 0.5 3.4e-19 69.7 0.5 3.7 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PRP82395.1 - 1.1e-20 73.5 0.8 2.1e-20 72.6 0.1 1.9 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 PRP82395.1 - 8.1e-19 67.4 1.1 1.8e-18 66.3 1.1 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 PRP82395.1 - 0.018 15.3 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain SAPS PF04499.15 PRP82395.1 - 5.2 5.7 11.9 8.1 5.1 11.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 PRP82395.1 - 8.4 6.6 16.3 16 5.7 16.3 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family WD40 PF00400.32 PRP82396.1 - 7.3e-24 83.6 13.9 1.1e-05 26.1 1.1 7.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Ank_2 PF12796.7 PRP82396.1 - 5.8e-22 78.1 0.6 3.3e-09 37.2 0.3 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP82396.1 - 1.3e-16 60.5 0.0 2.4e-06 27.7 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP82396.1 - 3.1e-15 56.3 0.0 3.3e-07 30.7 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) ANAPC4_WD40 PF12894.7 PRP82396.1 - 3.9e-15 55.9 4.1 3.6e-05 24.0 0.1 5.0 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ank PF00023.30 PRP82396.1 - 8e-14 51.4 0.0 2.5e-07 30.9 0.0 4.4 4 0 0 4 4 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP82396.1 - 2e-13 49.2 0.0 4.1e-05 23.7 0.0 4.7 5 0 0 5 5 4 2 Ankyrin repeat WW PF00397.26 PRP82396.1 - 1.5e-08 34.6 1.6 1.5e-08 34.6 1.6 2.2 2 0 0 2 2 2 1 WW domain eIF2A PF08662.11 PRP82396.1 - 3e-05 24.0 1.1 0.012 15.5 0.2 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PRP82396.1 - 0.00011 21.3 6.2 0.06 12.3 0.0 3.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Glyco_hyd_101C PF17451.2 PRP82396.1 - 0.0095 16.2 1.0 16 5.8 0.0 3.7 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain TAF6_C PF07571.13 PRP82397.1 - 1.2e-29 102.4 0.0 2.7e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 PRP82397.1 - 1.1e-21 76.8 0.0 2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 PRP82397.1 - 0.0089 16.4 0.3 0.027 14.8 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 ParcG PF10274.9 PRP82397.1 - 0.092 12.9 0.9 8.6 6.4 0.0 2.7 3 1 0 3 3 3 0 Parkin co-regulated protein TFIID-31kDa PF02291.15 PRP82397.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit ECH_1 PF00378.20 PRP82398.1 - 1.2e-34 119.8 0.0 1.6e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP82398.1 - 2.5e-19 70.0 0.0 6.7e-18 65.3 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase BTB PF00651.31 PRP82399.1 - 7.2e-17 61.6 0.0 1.5e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ank_5 PF13857.6 PRP82399.1 - 4e-07 30.2 0.0 1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP82399.1 - 0.0003 21.3 0.0 0.00067 20.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PRP82399.1 - 0.0093 16.4 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat COMP PF11598.8 PRP82399.1 - 0.026 15.0 2.8 1.5 9.3 0.8 2.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Ank_4 PF13637.6 PRP82399.1 - 0.036 14.6 0.0 0.97 10.1 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) CopG_antitoxin PF12441.8 PRP82399.1 - 0.09 13.3 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system ODC_AZ PF02100.17 PRP82400.1 - 3.3e-08 33.5 0.0 6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme GidB PF02527.15 PRP82400.1 - 0.034 13.5 0.4 0.046 13.0 0.1 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G rRNA_processing PF08524.11 PRP82402.1 - 7.4e-11 42.3 31.4 7.4e-11 42.3 31.4 2.3 1 1 1 2 2 2 1 rRNA processing SAPS PF04499.15 PRP82402.1 - 7.6 5.2 17.9 10 4.8 17.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SIP1 PF04938.12 PRP82403.1 - 0.029 14.1 0.2 0.057 13.1 0.2 1.5 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DnaB_bind PF10410.9 PRP82403.1 - 0.056 13.6 0.7 7.4 6.9 0.0 3.5 4 0 0 4 4 4 0 DnaB-helicase binding domain of primase Pkinase_Tyr PF07714.17 PRP82404.1 - 1.3e-76 257.4 0.0 2.1e-76 256.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82404.1 - 5.7e-48 163.6 0.0 8.3e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP82404.1 - 2.2e-42 142.6 82.6 1.5e-07 31.0 3.9 13.1 9 3 6 15 15 15 13 Leucine rich repeat LRR_4 PF12799.7 PRP82404.1 - 1.6e-29 101.4 81.3 0.00039 20.7 2.5 16.9 8 5 10 20 20 20 12 Leucine Rich repeats (2 copies) Abhydro_lipase PF04083.16 PRP82404.1 - 1.5e-16 59.7 0.0 2.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 PRP82404.1 - 3.2e-08 33.5 0.6 4.7e-07 29.7 0.1 3.0 3 1 0 3 3 3 1 alpha/beta hydrolase fold Kinase-like PF14531.6 PRP82404.1 - 5.8e-05 22.5 0.0 9.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Podoplanin PF05808.11 PRP82404.1 - 0.00027 21.1 0.6 0.00066 19.8 0.6 1.6 1 0 0 1 1 1 1 Podoplanin LRR_9 PF14580.6 PRP82404.1 - 0.00029 20.4 6.8 0.16 11.4 0.2 3.8 3 0 0 3 3 3 2 Leucine-rich repeat Hydrolase_4 PF12146.8 PRP82404.1 - 0.0073 15.6 1.8 0.17 11.1 1.2 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Insulin_TMD PF17870.1 PRP82404.1 - 0.009 16.1 2.6 0.009 16.1 2.6 2.0 2 0 0 2 2 1 1 Insulin receptor trans-membrane segment PTP_tm PF18861.1 PRP82404.1 - 0.081 12.9 2.4 0.2 11.6 2.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J FNIP PF05725.12 PRP82404.1 - 0.1 12.8 4.1 7.5 6.8 0.4 4.4 3 1 0 3 3 3 0 FNIP Repeat DUF4083 PF13314.6 PRP82404.1 - 0.14 12.1 1.6 0.38 10.7 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) YajC PF02699.15 PRP82404.1 - 0.23 11.4 1.1 0.55 10.2 0.2 2.0 2 0 0 2 2 2 0 Preprotein translocase subunit LRR_1 PF00560.33 PRP82404.1 - 0.27 11.9 66.3 13 6.8 0.2 20.1 24 2 0 24 24 21 0 Leucine Rich Repeat DUF1129 PF06570.11 PRP82404.1 - 0.33 10.4 3.7 6.1 6.3 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) LRR_12 PF18837.1 PRP82404.1 - 2.7 7.7 5.2 2.1 8.1 0.1 3.3 4 0 0 4 4 3 0 Leucine-rich repeat LRR_6 PF13516.6 PRP82404.1 - 6.3 7.1 49.7 6.7 7.0 0.1 15.8 20 0 0 20 20 18 0 Leucine Rich repeat Dynamin_M PF01031.20 PRP82407.1 - 5.7e-98 327.6 0.0 1.3e-97 326.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 PRP82407.1 - 6.9e-58 195.4 0.1 6.3e-57 192.3 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 PRP82407.1 - 3.3e-29 100.9 2.6 9.2e-29 99.5 2.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 PRP82407.1 - 4.6e-05 23.5 0.3 0.00022 21.3 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PRP82407.1 - 0.0036 17.7 0.0 0.079 13.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Roc PF08477.13 PRP82407.1 - 0.11 12.7 0.0 1.4 9.2 0.0 2.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 PRP82407.1 - 0.26 10.8 1.3 13 5.3 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B LRR_8 PF13855.6 PRP82408.1 - 2.5e-20 72.0 17.3 1.4e-08 34.4 0.4 4.0 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PRP82408.1 - 2e-18 66.2 19.2 8.4e-07 29.2 1.3 4.5 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP82408.1 - 4.1e-10 38.8 23.4 0.16 12.6 0.0 8.4 7 2 0 7 7 7 4 Leucine Rich Repeat LRR_9 PF14580.6 PRP82408.1 - 0.0069 15.9 1.6 0.0069 15.9 1.6 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRRNT_2 PF08263.12 PRP82408.1 - 0.069 13.5 2.6 0.14 12.4 2.6 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PRP82408.1 - 0.16 12.1 26.0 1 9.6 0.2 7.2 8 0 0 8 8 8 0 Leucine Rich repeat DEAD PF00270.29 PRP82409.1 - 1.6e-15 57.3 0.0 3.5e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP82409.1 - 4.2e-14 52.8 0.1 2.5e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 PRP82409.1 - 0.00023 21.8 1.8 0.00023 21.8 1.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) zf-TRAF PF02176.18 PRP82409.1 - 0.00056 20.5 4.3 0.00093 19.8 1.8 2.7 1 1 1 2 2 2 2 TRAF-type zinc finger LIN37 PF15306.6 PRP82410.1 - 1.2e-06 28.9 0.9 2e-05 24.9 0.9 2.2 1 1 0 1 1 1 1 LIN37 TLD PF07534.16 PRP82411.1 - 2.9e-24 85.9 0.2 9.7e-24 84.2 0.2 2.0 1 0 0 1 1 1 1 TLD PARP PF00644.20 PRP82411.1 - 5.9e-09 35.8 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RabGAP-TBC PF00566.18 PRP82411.1 - 6.6e-08 32.5 3.2 6.6e-08 32.5 3.2 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain BSD PF03909.17 PRP82411.1 - 5.5e-05 23.1 0.0 0.0002 21.3 0.0 1.9 1 0 0 1 1 1 1 BSD domain UBA PF00627.31 PRP82411.1 - 0.00044 20.1 0.0 0.00099 19.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Abhydrolase_1 PF00561.20 PRP82412.1 - 7.1e-15 55.3 0.1 1.9e-14 54.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP82412.1 - 1.8e-10 40.5 0.1 3.6e-10 39.5 0.1 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP82412.1 - 1.7e-05 25.6 0.0 2.6e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 PRP82412.1 - 0.0011 18.9 0.1 0.0023 17.9 0.1 1.4 1 0 0 1 1 1 1 Cutinase Palm_thioest PF02089.15 PRP82412.1 - 0.0091 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 PRP82412.1 - 0.039 13.3 0.1 0.091 12.1 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) GH43_C PF16369.5 PRP82414.1 - 0.002 18.7 0.1 0.0028 18.2 0.1 1.2 1 0 0 1 1 1 1 C-terminal lipocalin-like domain Ribosomal_L28e PF01778.17 PRP82415.1 - 3e-11 44.1 0.9 3.8e-11 43.7 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L28e protein family TPR_12 PF13424.6 PRP82416.1 - 2.1e-13 50.4 0.7 3.6e-05 24.0 0.0 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82416.1 - 5.9e-11 41.6 3.3 0.27 11.5 0.0 5.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 PRP82416.1 - 2.9e-09 36.4 6.1 0.46 10.4 0.0 5.8 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 PRP82416.1 - 0.00023 21.1 3.3 14 6.2 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP82416.1 - 0.00025 21.6 0.0 0.31 11.7 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 PRP82416.1 - 0.00026 20.5 0.1 0.0014 18.1 0.1 1.9 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_MalT PF17874.1 PRP82416.1 - 0.00075 19.0 0.1 0.0048 16.3 0.1 2.1 1 1 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 PRP82416.1 - 0.0045 16.9 0.2 8.4 6.7 0.1 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 PRP82416.1 - 0.029 13.8 0.0 0.085 12.3 0.0 1.8 1 0 0 1 1 1 0 SHNi-TPR PCI PF01399.27 PRP82417.1 - 5.1e-08 33.4 1.5 1.4e-07 32.0 0.2 2.4 2 0 0 2 2 2 1 PCI domain Nup88 PF10168.9 PRP82418.1 - 0.074 10.9 0.0 0.12 10.2 0.0 1.3 1 1 0 1 1 1 0 Nuclear pore component FANCI_HD2 PF14680.6 PRP82419.1 - 2.1e-35 122.1 0.3 8.4e-35 120.1 0.3 2.0 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S1 PF14675.6 PRP82419.1 - 3.4e-24 85.7 0.4 1.5e-23 83.6 0.0 2.4 3 0 0 3 3 3 1 FANCI solenoid 1 FANCI_S4 PF14678.6 PRP82419.1 - 7.5e-24 84.2 7.7 3.1e-23 82.2 7.7 2.1 1 0 0 1 1 1 1 FANCI solenoid 4 FANCI_S2 PF14676.6 PRP82419.1 - 2.5e-23 83.2 4.1 4.7e-23 82.3 0.2 3.6 4 1 0 4 4 4 1 FANCI solenoid 2 FANCI_HD1 PF14679.6 PRP82419.1 - 5.6e-10 39.0 0.1 5.6e-10 39.0 0.1 3.8 6 0 0 6 6 6 1 FANCI helical domain 1 Vac14_Fab1_bd PF12755.7 PRP82419.1 - 3.5 8.3 5.9 5.6 7.6 0.1 4.1 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Pkinase_Tyr PF07714.17 PRP82420.1 - 1.6e-63 214.4 0.0 2.8e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82420.1 - 6e-46 156.9 0.1 4.4e-45 154.1 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 PRP82420.1 - 1.1e-15 57.7 32.7 0.00029 21.6 0.6 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.6 PRP82420.1 - 3.1e-05 23.7 3.3 0.00021 20.9 0.4 2.4 2 0 0 2 2 2 1 PQQ-like domain PQQ_3 PF13570.6 PRP82420.1 - 0.00083 19.8 0.0 18 6.0 0.0 5.3 6 0 0 6 6 6 0 PQQ-like domain ANAPC4_WD40 PF12894.7 PRP82420.1 - 0.0022 18.2 2.7 0.38 11.1 0.2 4.1 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 PRP82420.1 - 0.093 12.7 0.1 1.2 9.2 0.0 2.9 3 0 0 3 3 3 0 PQQ enzyme repeat DUF4077 PF13295.6 PRP82420.1 - 1 9.2 3.7 0.35 10.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4077) DUF5082 PF16888.5 PRP82420.1 - 1.3 9.4 32.0 1.3 9.3 6.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) dCache_1 PF02743.18 PRP82420.1 - 4.4 7.0 9.9 0.091 12.5 0.7 2.7 3 0 0 3 3 3 0 Cache domain GMC_oxred_N PF00732.19 PRP82421.1 - 1e-27 97.3 0.0 2.5e-27 96.0 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP82421.1 - 4.6e-08 33.7 0.0 7.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PRP82421.1 - 0.00013 22.1 0.0 0.00032 20.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PRP82421.1 - 0.0043 16.2 0.1 0.0089 15.1 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 PRP82421.1 - 0.012 15.3 0.1 0.056 13.0 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP82421.1 - 0.021 13.5 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 PRP82421.1 - 0.07 12.4 0.0 0.17 11.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PRP82421.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 PRP82421.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 PRP82421.1 - 0.19 12.3 0.0 0.94 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_15 PF00723.21 PRP82422.1 - 1.1e-11 44.3 0.2 4.6e-08 32.3 0.1 3.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 TPR_14 PF13428.6 PRP82422.1 - 0.0088 16.8 0.2 0.033 15.0 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat RasGAP_C PF03836.15 PRP82422.1 - 0.014 15.6 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 RasGAP C-terminus TPR_2 PF07719.17 PRP82422.1 - 0.031 14.4 0.3 0.099 12.8 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 PRP82422.1 - 0.17 12.6 2.3 0.36 11.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP82422.1 - 0.22 12.1 0.4 1.1 9.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP82422.1 - 0.26 11.6 1.0 0.59 10.5 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP82422.1 - 0.82 9.6 4.3 0.71 9.8 0.6 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Alpha-amylase PF00128.24 PRP82423.1 - 2.3e-82 277.3 0.0 7.9e-82 275.5 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Allantoicase PF03561.15 PRP82423.1 - 1e-70 236.3 0.0 4.8e-42 143.3 0.0 2.6 2 1 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 PRP82423.1 - 2.3e-08 34.0 0.0 4.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Ureidoglycolate lyase Malt_amylase_C PF16657.5 PRP82423.1 - 4.1e-07 30.0 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain dCMP_cyt_deam_1 PF00383.23 PRP82425.1 - 1.3e-19 69.9 3.2 6.5e-13 48.4 0.2 2.9 3 0 0 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PRP82425.1 - 1.6e-05 24.7 0.3 0.00013 21.8 0.2 2.1 2 0 0 2 2 2 1 MafB19-like deaminase SNAD4 PF18750.1 PRP82425.1 - 0.00025 21.2 0.3 0.00057 20.0 0.3 1.6 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC4_like PF18774.1 PRP82425.1 - 0.00057 19.8 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC3 PF18771.1 PRP82425.1 - 0.0057 16.8 0.2 0.012 15.7 0.2 1.5 1 0 0 1 1 1 1 APOBEC3 NAD1 PF18778.1 PRP82425.1 - 0.023 14.8 0.1 0.089 12.9 0.2 1.9 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 MDM31_MDM32 PF08118.11 PRP82426.1 - 2.3e-44 152.0 1.5 1.3e-31 109.9 0.0 3.1 1 1 2 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins Inhibitor_I29 PF08246.12 PRP82427.1 - 0.17 12.4 0.2 0.17 12.4 0.2 2.8 4 0 0 4 4 4 0 Cathepsin propeptide inhibitor domain (I29) BRE1 PF08647.11 PRP82430.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Nop52 PF05997.12 PRP82431.1 - 0.0055 16.5 0.0 0.0058 16.4 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Kinesin PF00225.23 PRP82432.1 - 1.1e-95 320.4 0.6 1.1e-95 320.4 0.6 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP82432.1 - 1.2e-18 67.5 0.0 1.9e-14 53.8 0.0 3.0 2 0 0 2 2 2 2 Microtubule binding MKLP1_Arf_bdg PF16540.5 PRP82432.1 - 0.019 15.0 0.8 0.056 13.5 0.0 2.2 2 0 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 HAUS-augmin3 PF14932.6 PRP82432.1 - 0.17 11.5 17.8 0.41 10.2 17.8 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ECM11 PF15463.6 PRP82432.1 - 2.5 8.7 19.4 0.15 12.6 12.8 2.3 2 0 0 2 2 2 0 Extracellular mutant protein 11 Chisel PF15355.6 PRP82432.1 - 3.9 7.8 9.2 8 6.8 0.2 4.1 4 0 0 4 4 4 0 Stretch-responsive small skeletal muscle X protein, Chisel PorA PF11271.8 PRP82433.1 - 0.12 11.6 1.2 0.2 10.9 1.2 1.3 1 0 0 1 1 1 0 Porin PorA AFG1_ATPase PF03969.16 PRP82434.1 - 1e-95 320.7 0.1 1.2e-94 317.1 0.1 2.0 1 1 0 1 1 1 1 AFG1-like ATPase Bac_DnaA PF00308.18 PRP82434.1 - 1.1e-05 25.4 0.1 0.00086 19.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_16 PF13191.6 PRP82434.1 - 0.00016 22.1 0.1 0.022 15.1 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 PRP82434.1 - 0.0045 16.9 0.0 0.0091 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 PRP82434.1 - 0.028 14.9 0.0 0.18 12.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP82434.1 - 0.097 12.7 0.0 0.39 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PRP82434.1 - 0.1 13.0 0.0 1.6 9.2 0.0 2.8 3 0 0 3 3 3 0 RNA helicase RPAP2_Rtr1 PF04181.13 PRP82435.1 - 2e-22 79.3 2.5 5.1e-22 78.0 2.5 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family TBP PF00352.21 PRP82437.1 - 9e-42 140.9 0.0 2.9e-26 91.2 0.1 2.9 2 1 1 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) Peptidase_C71 PF12386.8 PRP82437.1 - 0.039 13.6 0.1 0.093 12.4 0.0 1.6 2 0 0 2 2 2 0 Pseudomurein endo-isopeptidase Pei HMA PF00403.26 PRP82437.1 - 0.045 14.2 0.0 2.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Heavy-metal-associated domain EBP PF05241.12 PRP82438.1 - 1.3e-28 99.7 3.9 1.5e-28 99.4 3.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein PH PF00169.29 PRP82439.1 - 1.8e-14 54.1 0.1 3e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 PH domain CH PF00307.31 PRP82439.1 - 1e-11 45.0 0.0 9.3e-07 29.0 0.1 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain PH_8 PF15409.6 PRP82439.1 - 4.2e-05 23.7 0.0 0.00013 22.1 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PRP82439.1 - 0.00012 22.4 2.0 0.00074 19.9 0.8 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PRP82439.1 - 0.013 15.5 0.0 0.057 13.5 0.0 2.0 1 1 0 1 1 1 0 PH domain Lactamase_B_6 PF16661.5 PRP82440.1 - 4.4e-10 39.3 0.0 1.5e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 PRP82440.1 - 3.6e-07 30.4 0.0 1.8e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Beta_lactamase3 PF17030.5 PRP82440.1 - 9.6e-06 25.0 0.2 8.1e-05 22.0 0.1 2.6 3 0 0 3 3 3 1 Putative beta-lactamase-like family UCH PF00443.29 PRP82441.1 - 1.2e-52 179.0 1.2 1.5e-52 178.6 1.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP82441.1 - 2.4e-22 79.9 5.0 5.4e-22 78.8 5.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PRP82441.1 - 6.9e-11 42.3 6.3 6.9e-11 42.3 6.3 3.3 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein TF_Zn_Ribbon PF08271.12 PRP82441.1 - 0.15 11.6 8.3 3.4 7.3 0.3 4.2 4 0 0 4 4 4 0 TFIIB zinc-binding Vps36-NZF-N PF16988.5 PRP82441.1 - 0.24 10.8 3.9 24 4.4 0.0 3.6 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DNA_RNApol_7kD PF03604.13 PRP82441.1 - 3.4 7.4 8.0 35 4.2 0.0 4.4 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit PIP5K PF01504.18 PRP82442.1 - 1.4e-33 116.3 0.3 3.3e-24 85.6 0.1 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 PRP82442.1 - 3.1e-28 98.7 0.0 5.5e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 PRP82442.1 - 8.9e-19 67.4 9.7 2.3e-18 66.1 9.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger AIF_C PF14721.6 PRP82442.1 - 0.055 13.8 0.2 0.42 11.0 0.1 2.6 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2789 PF10982.8 PRP82442.1 - 0.061 13.5 0.5 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) FYVE_2 PF02318.16 PRP82442.1 - 0.13 12.4 7.6 0.72 10.1 6.3 2.8 2 0 0 2 2 2 0 FYVE-type zinc finger DUF2370 PF10176.9 PRP82442.1 - 0.16 11.6 0.1 0.35 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) IBR PF01485.21 PRP82442.1 - 0.8 10.0 10.6 0.17 12.1 5.4 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain SepSecS PF05889.13 PRP82443.1 - 2.3e-134 448.0 0.0 2.9e-134 447.6 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 PRP82443.1 - 0.0064 15.8 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 PRP82443.1 - 0.009 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF3692 PF12469.8 PRP82443.1 - 0.016 15.4 0.0 1.6 8.9 0.0 2.7 2 1 0 2 2 2 0 CRISPR-associated protein NAD_Gly3P_dh_C PF07479.14 PRP82443.1 - 0.091 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pkinase_Tyr PF07714.17 PRP82444.1 - 0.00066 19.0 0.0 0.00096 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82444.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Phage_tail_NK PF16532.5 PRP82444.1 - 0.016 14.8 0.0 0.07 12.7 0.0 1.9 2 0 0 2 2 2 0 Sf6-type phage tail needle knob or tip of some Caudovirales LRR_8 PF13855.6 PRP82445.1 - 5.6e-10 38.8 7.4 3.3e-06 26.8 0.3 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PRP82445.1 - 4.7e-09 36.4 10.9 0.00012 22.4 0.1 4.2 3 2 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP82445.1 - 6.5e-07 28.9 5.5 0.19 11.9 0.0 4.0 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 PRP82445.1 - 1.7e-06 27.8 9.2 0.21 12.3 0.0 5.0 4 1 0 4 4 4 3 Leucine Rich Repeat TFIIB PF00382.19 PRP82446.1 - 1.3e-07 31.6 0.8 0.0087 16.1 0.0 3.8 4 0 0 4 4 4 2 Transcription factor TFIIB repeat zf-Di19 PF05605.12 PRP82446.1 - 0.11 12.8 4.5 0.13 12.5 1.9 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PhnA_Zn_Ribbon PF08274.12 PRP82446.1 - 0.24 11.4 5.7 0.066 13.2 2.6 1.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-FPG_IleRS PF06827.14 PRP82446.1 - 0.55 10.2 4.7 18 5.3 4.6 3.2 2 1 0 2 2 2 0 Zinc finger found in FPG and IleRS Amnionless PF14828.6 PRP82447.1 - 0.0053 15.6 0.1 0.0095 14.8 0.1 1.4 1 0 0 1 1 1 1 Amnionless Colicin_D PF11429.8 PRP82447.1 - 0.017 15.6 0.1 0.05 14.0 0.1 1.8 1 0 0 1 1 1 0 Colicin D DUF3079 PF11278.8 PRP82447.1 - 0.076 12.8 0.4 9.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) Pkinase PF00069.25 PRP82448.1 - 1.2e-60 205.1 0.0 1.4e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82448.1 - 2.8e-15 56.3 0.0 3.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP82448.1 - 5.9e-09 36.2 0.1 7.6e-07 29.3 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP82448.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF2459 PF09601.10 PRP82448.1 - 0.092 12.5 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) Pkinase_fungal PF17667.1 PRP82448.1 - 0.11 11.2 0.1 0.22 10.3 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase DUF3336 PF11815.8 PRP82451.1 - 2.4e-34 118.0 3.8 4.4e-34 117.2 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 PRP82451.1 - 1.4e-21 77.6 0.7 6.9e-15 55.8 0.0 3.0 3 0 0 3 3 3 2 Patatin-like phospholipase LIM PF00412.22 PRP82451.1 - 8.9e-11 41.9 5.1 8.9e-11 41.9 5.1 2.3 2 0 0 2 2 2 1 LIM domain zf_UBZ PF18439.1 PRP82451.1 - 0.048 13.3 2.5 8 6.2 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 PRP82451.1 - 0.049 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger Ribosomal_L37e PF01907.19 PRP82451.1 - 2.7 8.2 6.6 18 5.6 2.9 2.8 2 0 0 2 2 2 0 Ribosomal protein L37e UDPGP PF01704.18 PRP82453.1 - 7.4e-49 166.5 0.0 1.2e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PDZ_1 PF12812.7 PRP82453.1 - 2.1e-26 91.7 0.0 2.2e-16 59.6 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 PRP82453.1 - 4.8e-20 73.0 0.0 1.1e-17 65.3 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 PRP82453.1 - 4.1e-17 61.8 0.1 3.7e-05 23.5 0.1 4.0 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 PRP82453.1 - 1.6e-16 60.4 0.3 0.00013 22.2 0.0 4.5 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 PRP82453.1 - 6.6e-11 42.4 0.0 0.01 16.1 0.0 4.5 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 PRP82453.1 - 0.00097 19.1 0.4 2 8.4 0.2 3.8 4 0 0 4 4 4 1 Tricorn protease PDZ domain NTP_transf_3 PF12804.7 PRP82453.1 - 0.023 15.0 0.1 0.069 13.5 0.1 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain PDZ_3 PF17815.1 PRP82453.1 - 0.063 13.1 0.0 6.8 6.6 0.0 2.5 2 0 0 2 2 2 0 PDZ domain Peptidase_S46 PF10459.9 PRP82453.1 - 0.07 11.8 0.0 0.31 9.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase S46 Peptidase_S7 PF00949.21 PRP82453.1 - 0.18 11.6 0.2 0.64 9.9 0.2 1.9 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease LIM PF00412.22 PRP82454.1 - 4.4e-10 39.6 5.8 6.9e-10 39.0 5.8 1.3 1 0 0 1 1 1 1 LIM domain DUF3103 PF11301.8 PRP82454.1 - 0.059 12.2 0.2 0.071 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) FpoO PF10621.9 PRP82454.1 - 0.37 11.1 9.5 1.7 9.0 5.3 3.0 2 1 1 3 3 3 0 F420H2 dehydrogenase subunit FpoO zf-C3HC4_5 PF17121.5 PRP82454.1 - 1.2 9.1 5.6 0.37 10.7 1.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4955 PF16315.5 PRP82458.1 - 2e-05 24.8 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4955) Arf PF00025.21 PRP82459.1 - 1.2e-59 200.6 0.1 2.9e-59 199.5 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Ank_2 PF12796.7 PRP82459.1 - 4.4e-23 81.7 0.1 3.9e-09 37.0 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82459.1 - 1.1e-13 51.4 0.1 0.00046 20.7 0.0 4.8 3 2 2 5 5 5 2 Ankyrin repeats (many copies) SRPRB PF09439.10 PRP82459.1 - 4.1e-11 42.7 0.0 7.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PRP82459.1 - 4.5e-11 43.0 0.0 1.1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_3 PF13606.6 PRP82459.1 - 8.1e-10 38.1 0.0 1.1 10.0 0.0 7.4 8 0 0 8 8 7 2 Ankyrin repeat G-alpha PF00503.20 PRP82459.1 - 5.6e-09 35.6 1.4 6.6e-06 25.5 0.2 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 PRP82459.1 - 1.3e-08 34.6 0.0 2.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Ank PF00023.30 PRP82459.1 - 8.7e-08 32.3 1.8 4.9 7.8 0.0 6.1 7 0 0 7 7 6 2 Ankyrin repeat Gtr1_RagA PF04670.12 PRP82459.1 - 1.6e-07 30.9 0.0 3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ank_5 PF13857.6 PRP82459.1 - 3.5e-07 30.4 0.5 4.5 7.7 0.0 5.6 2 1 3 5 5 5 2 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 PRP82459.1 - 0.0035 17.4 0.0 0.0095 16.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase MIP-T3 PF10243.9 PRP82460.1 - 2.1e-42 143.7 0.1 5.9e-42 142.2 0.1 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 PRP82460.1 - 1.7e-34 119.0 14.3 1.7e-34 119.0 14.3 2.8 2 1 0 2 2 1 1 Microtubule-binding protein MIP-T3 C-terminal region DUF948 PF06103.11 PRP82460.1 - 0.0053 17.0 0.3 0.028 14.7 0.1 2.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Macoilin PF09726.9 PRP82460.1 - 0.052 12.1 19.5 0.12 10.9 19.5 1.6 1 0 0 1 1 1 0 Macoilin family DnaB_bind PF10410.9 PRP82460.1 - 0.054 13.7 0.1 15 5.8 0.0 3.0 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Syntaxin-6_N PF09177.11 PRP82460.1 - 0.96 10.0 7.7 1.5 9.4 4.5 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal PIN_4 PF13638.6 PRP82460.1 - 1.5 9.1 6.4 0.44 10.8 2.3 2.3 2 0 0 2 2 2 0 PIN domain YabA PF06156.13 PRP82460.1 - 1.7 9.4 8.1 19 5.9 2.7 3.3 1 1 1 2 2 2 0 Initiation control protein YabA Lectin_N PF03954.14 PRP82460.1 - 1.8 8.3 4.5 7.3 6.4 4.5 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Tup_N PF08581.10 PRP82460.1 - 1.9 8.9 13.1 2 8.8 4.6 3.8 3 0 0 3 3 3 0 Tup N-terminal DUF1664 PF07889.12 PRP82460.1 - 3.6 7.6 10.3 2.9 7.9 3.0 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 PRP82460.1 - 8.2 6.6 17.2 0.81 9.9 8.6 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family SPRY PF00622.28 PRP82461.1 - 5.9e-09 36.1 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Glyco_transf_54 PF04666.13 PRP82463.1 - 2.4e-23 82.4 0.0 5.9e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF1201 PF06716.11 PRP82463.1 - 0.15 12.1 3.0 0.29 11.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Nop25 PF09805.9 PRP82464.1 - 1.4e-22 80.6 19.6 1.4e-22 80.6 19.6 2.5 2 2 0 2 2 2 1 Nucleolar protein 12 (25kDa) WWE PF02825.20 PRP82465.1 - 1.1e-11 45.2 1.7 1.1e-11 45.2 1.7 2.1 2 1 0 2 2 2 1 WWE domain Linker_histone PF00538.19 PRP82465.1 - 3.5e-07 30.5 0.1 6.9e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family pKID PF02173.17 PRP82465.1 - 0.0067 15.9 0.2 0.021 14.3 0.2 1.8 1 0 0 1 1 1 1 pKID domain DUF5137 PF17220.3 PRP82465.1 - 0.057 14.3 1.2 0.11 13.4 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF5137) adh_short PF00106.25 PRP82468.1 - 5e-43 146.8 0.1 8.3e-43 146.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP82468.1 - 7.5e-28 97.7 0.2 1.1e-27 97.1 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP82468.1 - 5.8e-07 29.6 0.3 2.7e-06 27.4 0.3 1.9 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 PRP82468.1 - 3.4e-06 26.6 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 PRP82468.1 - 0.011 15.3 0.1 0.023 14.2 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP82468.1 - 0.072 13.0 2.5 0.43 10.4 1.4 2.4 1 1 1 2 2 2 0 NAD(P)H-binding LIM PF00412.22 PRP82469.1 - 2.4e-09 37.3 5.8 4.6e-09 36.4 5.8 1.5 1 0 0 1 1 1 1 LIM domain FpoO PF10621.9 PRP82469.1 - 2.2 8.6 11.1 7.6 6.9 4.9 3.3 2 1 1 3 3 3 0 F420H2 dehydrogenase subunit FpoO UDPGP PF01704.18 PRP82470.1 - 1.6e-48 165.4 0.0 2.5e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PDZ_1 PF12812.7 PRP82470.1 - 6e-26 90.3 0.0 3.8e-16 58.9 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 PRP82470.1 - 1.6e-19 71.3 0.0 1.9e-17 64.5 0.0 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 PRP82470.1 - 2.5e-16 59.3 0.2 6.2e-05 22.8 0.1 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 PRP82470.1 - 7.1e-16 58.3 0.3 0.00023 21.4 0.0 4.9 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 PRP82470.1 - 4.9e-10 39.6 0.0 0.017 15.4 0.0 4.4 4 0 0 4 4 4 2 PDZ domain Patatin PF01734.22 PRP82470.1 - 0.00071 19.8 0.6 0.0024 18.1 0.2 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase Tricorn_PDZ PF14685.6 PRP82470.1 - 0.0047 16.9 0.5 3.3 7.7 0.2 3.7 3 0 0 3 3 3 1 Tricorn protease PDZ domain NTP_transf_3 PF12804.7 PRP82470.1 - 0.043 14.2 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Peptidase_S46 PF10459.9 PRP82470.1 - 0.16 10.6 0.0 0.52 8.9 0.0 1.7 2 0 0 2 2 2 0 Peptidase S46 DUF3336 PF11815.8 PRP82471.1 - 8.7e-35 119.4 2.8 1.7e-34 118.5 2.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 PRP82471.1 - 1.1e-15 58.4 0.0 2.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase KTI12 PF08433.10 PRP82473.1 - 0.0036 16.8 0.0 0.082 12.3 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Nepo_coat_N PF03689.15 PRP82475.1 - 0.031 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain Spherulin4 PF12138.8 PRP82475.1 - 0.043 13.5 0.5 0.05 13.2 0.5 1.1 1 0 0 1 1 1 0 Spherulation-specific family 4 LURAP PF14854.6 PRP82475.1 - 0.058 13.3 2.6 0.33 10.9 0.5 2.8 2 1 0 3 3 3 0 Leucine rich adaptor protein TIP120 PF08623.10 PRP82475.1 - 0.16 11.7 8.2 0.14 11.9 6.5 1.7 1 1 0 1 1 1 0 TATA-binding protein interacting (TIP20) Urm1 PF09138.11 PRP82475.1 - 0.22 11.9 1.7 0.51 10.7 1.4 1.8 1 1 0 1 1 1 0 Urm1 (Ubiquitin related modifier) MutS_III PF05192.18 PRP82475.1 - 0.57 10.4 3.5 0.77 9.9 3.5 1.2 1 0 0 1 1 1 0 MutS domain III ACP53EA PF06313.11 PRP82476.1 - 0.056 13.6 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Drosophila ACP53EA protein AAA_22 PF13401.6 PRP82477.1 - 0.0055 17.0 0.0 0.022 15.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain 4PPT_N PF17837.1 PRP82477.1 - 0.34 11.1 1.7 0.48 10.6 0.2 2.0 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain DUF667 PF05018.13 PRP82484.1 - 7.1e-47 159.5 1.4 3.3e-39 134.5 0.2 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF667) LRR_9 PF14580.6 PRP82485.1 - 3.3e-09 36.5 1.9 6.5e-06 25.8 2.0 2.3 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 PRP82485.1 - 7.4e-07 28.8 18.7 1.6e-05 24.6 4.7 3.3 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 PRP82485.1 - 3.5e-06 27.3 18.6 0.0045 17.4 0.1 4.6 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) ANAPC4_WD40 PF12894.7 PRP82485.1 - 3.9e-06 27.1 0.0 0.52 10.7 0.0 4.0 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP82485.1 - 1.7e-05 25.5 2.8 0.028 15.3 0.1 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat LRR_1 PF00560.33 PRP82485.1 - 8.9 7.3 6.8 86 4.3 0.1 4.1 4 1 0 4 4 4 0 Leucine Rich Repeat Dimer_Tnp_hAT PF05699.14 PRP82488.1 - 0.0026 17.5 0.0 0.0073 16.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Corona_I PF03187.14 PRP82488.1 - 0.0042 16.8 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 1 Corona nucleocapsid I protein DUF4413 PF14372.6 PRP82488.1 - 0.0047 17.3 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) GSK-3_bind PF05350.12 PRP82488.1 - 0.011 15.0 0.2 0.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Glycogen synthase kinase-3 binding DUF1031 PF06275.11 PRP82488.1 - 0.061 13.6 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) YfhD PF14151.6 PRP82488.1 - 0.3 11.3 5.4 11 6.3 0.2 3.3 2 0 0 2 2 2 0 YfhD-like protein DUF5300 PF17224.3 PRP82490.1 - 0.0022 18.2 0.3 0.021 15.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5300) Ta0938 PF11494.8 PRP82490.1 - 0.084 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Ta0938 DUF1289 PF06945.13 PRP82490.1 - 0.23 11.3 1.7 0.58 10.0 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) PPL5 PF18168.1 PRP82490.1 - 0.42 9.8 3.5 0.7 9.1 3.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Pro_isomerase PF00160.21 PRP82492.1 - 5.2e-42 143.8 0.4 1.2e-41 142.6 0.4 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD APG6_N PF17675.1 PRP82493.1 - 0.11 13.0 21.2 0.15 12.5 21.2 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Phage_TAC_4 PF08748.11 PRP82493.1 - 0.41 11.0 6.8 0.58 10.5 6.8 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone DIT1_PvcA PF05141.12 PRP82496.1 - 5.1e-61 206.6 0.1 2.3e-60 204.4 0.0 2.2 2 1 0 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 PRP82496.1 - 1.9e-11 44.3 0.0 6.7e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.19 PRP82497.1 - 2e-49 168.7 0.0 5.7e-49 167.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Glyco_transf_90 PF05686.12 PRP82497.1 - 3.9e-14 52.4 0.3 4.4e-08 32.5 0.1 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 90 Nup84_Nup100 PF04121.13 PRP82498.1 - 1.3e-75 255.0 15.2 4e-74 250.1 9.4 2.0 1 1 0 2 2 2 2 Nuclear pore protein 84 / 107 MOZ_SAS PF01853.18 PRP82498.1 - 0.011 15.5 1.5 0.015 15.0 0.2 1.9 2 0 0 2 2 2 0 MOZ/SAS family RasGEF PF00617.19 PRP82499.1 - 2.5e-43 148.3 3.0 6.6e-43 147.0 2.0 2.4 2 0 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 PRP82499.1 - 1.1e-28 98.8 36.2 7e-10 38.5 0.1 6.8 1 1 9 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 PRP82499.1 - 5.8e-27 93.3 41.5 8.2e-07 29.3 1.4 8.7 4 2 3 9 9 9 9 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 PRP82499.1 - 7.3e-18 64.7 1.0 7.3e-18 64.7 1.0 4.6 5 0 0 5 5 5 1 RasGEF N-terminal motif Drf_FH3 PF06367.16 PRP82499.1 - 2.2e-12 47.0 6.7 5.4e-12 45.7 5.2 2.5 2 0 0 2 2 2 1 Diaphanous FH3 Domain LRR_9 PF14580.6 PRP82499.1 - 2.6e-09 36.8 14.5 0.00021 20.8 0.3 4.3 1 1 2 3 3 3 3 Leucine-rich repeat Drf_GBD PF06371.13 PRP82499.1 - 6.3e-05 22.6 0.2 0.00037 20.1 0.2 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain FERM_N PF09379.10 PRP82499.1 - 0.002 18.0 0.1 4.4 7.3 0.0 3.5 3 0 0 3 3 3 2 FERM N-terminal domain RA PF00788.23 PRP82499.1 - 0.031 14.9 0.0 1 10.0 0.0 3.0 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain DUF4571 PF15137.6 PRP82499.1 - 0.036 13.7 0.7 0.34 10.5 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4571) LRR_6 PF13516.6 PRP82499.1 - 1.8 8.8 28.0 2.9 8.2 0.0 8.8 10 0 0 10 10 10 0 Leucine Rich repeat EI24 PF07264.11 PRP82500.1 - 1.8e-19 70.7 1.4 1.8e-19 70.7 1.4 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FtsX PF02687.21 PRP82500.1 - 1.1 9.8 6.9 6.7 7.3 0.4 2.7 2 1 0 2 2 2 0 FtsX-like permease family EXS PF03124.14 PRP82501.1 - 7.9e-91 304.8 35.4 1.1e-90 304.4 35.4 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 PRP82501.1 - 2.4e-18 67.3 21.1 1.9e-17 64.3 21.1 2.5 1 1 0 1 1 1 1 SPX domain MPP6 PF10175.9 PRP82501.1 - 7.7e-06 26.4 6.8 2.3e-05 24.9 6.8 1.8 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Atrophin-1 PF03154.15 PRP82501.1 - 4.3 5.5 6.9 6.5 4.9 6.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.32 PRP82502.1 - 9.7e-16 57.9 4.0 0.00043 21.0 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82502.1 - 2.7e-07 30.8 0.1 0.041 14.2 0.0 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP82502.1 - 2.4e-05 24.3 0.1 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 PRP82502.1 - 0.11 11.5 0.1 5.3 6.0 0.0 2.6 2 1 0 2 2 2 0 Coatomer WD associated region LRR_8 PF13855.6 PRP82503.1 - 2.7e-21 75.1 17.9 3.4e-08 33.1 5.6 3.7 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PRP82503.1 - 1.1e-13 51.1 21.1 0.00048 20.5 0.0 5.1 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP82503.1 - 0.0059 17.0 16.9 7.1 7.6 0.1 7.7 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP82503.1 - 2.2 8.6 17.0 19 5.6 0.0 6.4 6 1 0 7 7 7 0 Leucine Rich repeat LCM PF04072.14 PRP82504.1 - 1.9e-32 112.7 0.0 9.5e-32 110.5 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Trp_syntA PF00290.20 PRP82505.1 - 7.2e-85 283.9 1.9 3.3e-84 281.8 0.1 2.1 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 PRP82505.1 - 1.5e-48 165.7 0.7 2.2e-48 165.1 0.7 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 PRP82505.1 - 0.064 12.7 0.0 0.22 11.0 0.0 1.9 1 0 0 1 1 1 0 Histidine biosynthesis protein FAD_binding_3 PF01494.19 PRP82506.1 - 7.4e-18 64.9 0.3 1.7e-15 57.2 0.3 2.4 1 1 0 1 1 1 1 FAD binding domain Glyoxalase PF00903.25 PRP82506.1 - 6e-07 29.7 0.0 2.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily NAD_binding_8 PF13450.6 PRP82506.1 - 0.0028 17.8 0.1 0.0066 16.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PRP82506.1 - 0.015 14.6 0.1 6.7 5.9 0.1 2.7 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 PRP82506.1 - 0.084 12.1 0.0 0.23 10.7 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP82506.1 - 0.15 12.6 0.9 0.41 11.2 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP82506.1 - 0.19 11.3 0.1 2.8 7.4 0.2 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Laminin_G_3 PF13385.6 PRP82508.1 - 9.7e-36 123.2 7.1 6.3e-18 65.4 0.0 3.1 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Toxin_R_bind_N PF07953.12 PRP82508.1 - 0.00032 20.5 1.4 0.88 9.3 0.6 2.9 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding DUF4982 PF16355.5 PRP82508.1 - 0.0076 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) SOG2 PF10428.9 PRP82508.1 - 8.9 5.4 13.0 19 4.3 13.0 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Bap31 PF05529.12 PRP82509.1 - 4.2e-21 75.2 6.4 9.8e-21 74.0 6.4 1.6 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region UPF0242 PF06785.11 PRP82509.1 - 0.17 11.9 27.4 1.1 9.4 14.2 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 PRP82509.1 - 0.26 11.6 7.5 0.13 12.6 0.3 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4407 PF14362.6 PRP82509.1 - 0.41 9.9 17.3 0.022 14.1 7.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) LIN52 PF10044.9 PRP82509.1 - 0.98 10.2 0.0 0.98 10.2 0.0 3.0 3 0 0 3 3 3 0 Retinal tissue protein ERM PF00769.19 PRP82509.1 - 1.3 8.8 33.4 1.6 8.5 4.4 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.9 PRP82509.1 - 2.9 8.2 20.9 3 8.2 8.2 3.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_TATA_bd PF12325.8 PRP82509.1 - 3.8 7.8 21.2 5.2 7.3 13.3 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 PRP82509.1 - 6.7 6.8 17.0 0.63 10.1 7.4 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) PspB PF06667.12 PRP82509.1 - 9.9 6.3 8.2 0.6 10.2 1.0 2.7 2 0 0 2 2 2 0 Phage shock protein B Transket_pyr PF02779.24 PRP82510.1 - 3.1e-58 196.4 0.0 4.9e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 PRP82510.1 - 4.8e-54 183.3 0.0 7.3e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 PRP82510.1 - 2e-43 147.7 0.0 4.3e-43 146.6 0.0 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal YhfZ_C PF14503.6 PRP82510.1 - 0.05 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain AAA_12 PF13087.6 PRP82511.1 - 3.5e-12 46.4 0.0 1e-11 44.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PRP82511.1 - 0.0011 19.3 0.0 0.0044 17.4 0.1 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 PRP82511.1 - 0.31 11.0 1.4 4.9 7.1 0.1 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PH PF00169.29 PRP82512.1 - 5.8e-12 46.1 0.1 1.1e-11 45.2 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 PRP82512.1 - 0.02 15.1 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_8 PF13855.6 PRP82513.1 - 6e-69 227.7 100.1 7.6e-09 35.2 6.1 13.6 6 3 7 16 16 16 14 Leucine rich repeat LRR_4 PF12799.7 PRP82513.1 - 3.5e-49 163.9 104.8 7.4e-05 23.0 0.3 16.3 7 3 11 19 19 19 17 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP82513.1 - 1.3e-17 61.6 90.8 0.37 11.5 0.2 24.9 25 1 1 26 26 26 5 Leucine Rich Repeat GPS PF01825.21 PRP82513.1 - 6.8e-09 36.1 2.3 1.9e-08 34.7 2.3 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pox_A14 PF05767.12 PRP82513.1 - 0.029 14.5 0.1 0.059 13.5 0.1 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 TMEM154 PF15102.6 PRP82513.1 - 0.052 13.5 1.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family CD34_antigen PF06365.12 PRP82513.1 - 0.056 13.0 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 CD34/Podocalyxin family Syndecan PF01034.20 PRP82513.1 - 0.082 12.8 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain TNFR_16_TM PF18422.1 PRP82513.1 - 0.12 12.4 0.8 0.25 11.3 0.8 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF456 PF04306.13 PRP82513.1 - 0.12 12.7 0.7 0.23 11.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) LRR_6 PF13516.6 PRP82513.1 - 0.68 10.1 97.9 0.78 9.9 0.2 21.0 23 0 0 23 23 23 0 Leucine Rich repeat DUF131 PF01998.17 PRP82513.1 - 1.6 8.4 9.1 5.6 6.7 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function DUF131 LRR_9 PF14580.6 PRP82513.1 - 6.7 6.2 19.6 1.6 8.2 0.1 5.7 3 2 2 6 6 6 0 Leucine-rich repeat EMC1_C PF07774.13 PRP82514.1 - 1.6e-66 224.1 0.1 2.8e-66 223.3 0.1 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 PRP82514.1 - 3.4e-09 36.7 2.2 5.4e-06 26.2 0.2 4.5 3 1 1 4 4 4 2 PQQ-like domain VCBS PF13517.6 PRP82514.1 - 0.036 14.7 0.1 0.26 11.9 0.1 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 PRP82514.1 - 0.16 11.9 2.0 1.1e+02 3.0 0.0 5.2 6 0 0 6 6 6 0 PQQ enzyme repeat Histone PF00125.24 PRP82517.1 - 1e-17 64.7 0.0 1.3e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 PRP82517.1 - 6.1e-11 41.9 0.6 6.1e-11 41.9 0.6 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 PRP82517.1 - 0.00046 20.4 0.0 0.0014 18.9 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_S2 PF00318.20 PRP82519.1 - 1.4e-28 99.7 0.0 1.1e-14 54.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 HU-CCDC81_euk_2 PF18289.1 PRP82520.1 - 5.3e-06 26.5 0.0 6.6e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 PRP82520.1 - 0.002 18.3 0.0 0.0066 16.6 0.0 1.9 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 Hormone_1 PF00103.20 PRP82520.1 - 9.3 5.9 12.0 3.4 7.4 0.3 2.5 2 0 0 2 2 2 0 Somatotropin hormone family Peroxidase_2 PF01328.17 PRP82521.1 - 4.2e-12 47.0 2.7 7.7e-08 33.1 0.3 3.1 1 1 1 2 2 2 2 Peroxidase, family 2 adh_short_C2 PF13561.6 PRP82523.1 - 2.6e-54 184.3 0.1 3.2e-54 184.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP82523.1 - 8.9e-45 152.6 0.6 1.1e-44 152.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP82523.1 - 8.9e-08 32.2 0.2 1.2e-07 31.8 0.2 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PRP82523.1 - 0.0058 16.0 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Grg1 PF11034.8 PRP82523.1 - 0.036 14.3 0.1 0.069 13.4 0.1 1.4 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 THF_DHG_CYH_C PF02882.19 PRP82523.1 - 0.11 11.9 0.3 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TraK PF06586.11 PRP82523.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 TraK protein Abhydrolase_1 PF00561.20 PRP82525.1 - 1.3e-20 74.1 0.0 2.8e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP82525.1 - 5.9e-15 56.5 0.1 7.7e-15 56.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP82525.1 - 3.2e-08 33.2 0.0 4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 PRP82525.1 - 0.01 15.7 0.0 4.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase Thioesterase PF00975.20 PRP82525.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S28 PF05577.12 PRP82526.1 - 3.8e-83 279.7 0.0 5.5e-83 279.2 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 PRP82526.1 - 4.3e-09 35.6 0.1 7.4e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_1 PF00561.20 PRP82526.1 - 0.00027 20.7 0.1 0.00059 19.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP82526.1 - 0.00048 19.7 0.2 0.0018 17.8 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PRP82526.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 S_100 PF01023.19 PRP82526.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain HD_5 PF13487.6 PRP82526.1 - 0.04 14.2 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 HD domain DUF2920 PF11144.8 PRP82526.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Aminotran_3 PF00202.21 PRP82528.1 - 3.1e-84 283.0 0.0 3.7e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF4868 PF16162.5 PRP82528.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) Yip1 PF04893.17 PRP82530.1 - 2.4e-11 43.6 15.1 4e-11 42.9 15.0 1.4 1 1 0 1 1 1 1 Yip1 domain LRR_9 PF14580.6 PRP82531.1 - 4.6e-74 247.7 4.6 6e-74 247.3 4.6 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PRP82531.1 - 1.4e-09 38.0 13.8 4e-05 23.9 7.5 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP82531.1 - 6.5e-09 35.4 15.2 7.9e-07 28.7 7.3 2.9 2 1 1 3 3 3 2 Leucine rich repeat GA PF01468.17 PRP82531.1 - 0.0094 16.2 1.6 0.0094 16.2 1.6 2.6 2 0 0 2 2 2 1 GA module Recep_L_domain PF01030.24 PRP82531.1 - 0.016 15.3 1.1 0.038 14.1 0.4 1.9 1 1 0 1 1 1 0 Receptor L domain SNAPc_SNAP43 PF09808.9 PRP82531.1 - 0.14 12.1 2.0 0.2 11.5 2.0 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 MJ1316 PF04457.12 PRP82532.1 - 3.5e-18 66.1 0.7 3.5e-18 66.1 0.7 2.0 2 0 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain PrmA PF06325.13 PRP82533.1 - 3.5e-10 39.8 0.0 4.9e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PRP82533.1 - 2.6e-08 33.8 0.0 5.1e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PRP82533.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP82533.1 - 1.1e-05 26.1 0.0 2.9e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PRMT5_C PF17286.2 PRP82533.1 - 3.1e-05 23.9 0.0 5.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Cons_hypoth95 PF03602.15 PRP82533.1 - 0.00039 20.1 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 PRP82533.1 - 0.00042 20.1 0.0 0.00064 19.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.16 PRP82533.1 - 0.00075 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 PRP82533.1 - 0.0011 19.7 0.0 0.0018 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PRP82533.1 - 0.0028 17.6 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 PRP82533.1 - 0.0091 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase JTB PF05439.12 PRP82534.1 - 0.01 15.9 9.1 0.1 12.6 1.1 2.3 1 1 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) COX17 PF05051.13 PRP82534.1 - 0.046 14.1 0.3 0.046 14.1 0.3 1.6 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF3724 PF12521.8 PRP82539.1 - 1.6 8.8 0.0 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3724) DUF5554 PF17709.1 PRP82540.1 - 0.026 14.6 0.2 0.068 13.3 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5554) Paf1 PF03985.13 PRP82541.1 - 1.6e-50 172.4 0.4 2.2e-50 171.9 0.4 1.1 1 0 0 1 1 1 1 Paf1 zf_CCCH_4 PF18345.1 PRP82542.1 - 9e-17 60.5 29.2 5.6e-06 26.2 2.1 3.5 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 PRP82542.1 - 1.5e-14 53.5 21.4 3.8e-05 23.5 3.1 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PRP82542.1 - 7.7e-14 51.1 23.2 0.00024 20.8 0.4 3.8 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 PRP82542.1 - 1e-06 29.4 12.3 0.0027 18.4 0.5 3.2 2 1 1 3 3 3 3 Torus domain zf-CCCH_2 PF14608.6 PRP82542.1 - 5e-05 23.6 29.1 0.0052 17.2 3.0 3.8 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 PRP82542.1 - 0.00016 21.8 15.3 0.03 14.5 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger containing family zf-RING_UBOX PF13445.6 PRP82542.1 - 0.00018 21.4 5.2 0.00018 21.4 5.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PRP82542.1 - 0.00064 20.0 5.1 0.00064 20.0 5.1 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP82542.1 - 0.00071 19.4 5.4 0.00071 19.4 5.4 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 PRP82542.1 - 0.0014 18.5 1.6 0.0014 18.5 1.6 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 PRP82542.1 - 0.0032 17.3 6.6 0.0032 17.3 6.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP82542.1 - 0.0052 16.7 5.5 0.0052 16.7 5.5 2.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 PRP82542.1 - 0.0074 16.0 7.0 0.0074 16.0 7.0 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 PRP82542.1 - 0.34 11.1 7.2 4.8 7.4 7.3 2.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Gliadin PF13016.6 PRP82542.1 - 3.7 8.0 10.4 1.3 9.5 5.8 2.3 2 1 0 2 2 2 0 Cys-rich Gliadin N-terminal Myosin_head PF00063.21 PRP82543.1 - 1.9e-240 799.7 2.0 2.8e-240 799.2 2.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 PRP82543.1 - 3.9e-23 81.7 0.1 2.7e-22 79.0 0.0 2.6 2 0 0 2 2 2 1 DIL domain Spc7 PF08317.11 PRP82543.1 - 0.046 12.6 41.7 0.17 10.8 26.2 3.7 2 1 2 4 4 4 0 Spc7 kinetochore protein AAA_22 PF13401.6 PRP82543.1 - 0.075 13.3 0.0 0.31 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 PRP82543.1 - 0.077 12.7 0.0 17 5.1 0.0 2.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 PRP82543.1 - 0.089 13.2 0.0 0.089 13.2 0.0 3.6 2 1 0 2 2 1 0 AAA ATPase domain TsaE PF02367.17 PRP82543.1 - 0.095 12.7 0.5 2 8.4 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Hpr_kinase_C PF07475.12 PRP82543.1 - 0.097 12.2 0.1 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain SlyX PF04102.12 PRP82543.1 - 0.63 10.7 12.7 43 4.8 0.8 4.7 2 1 1 3 3 3 0 SlyX Fib_alpha PF08702.10 PRP82543.1 - 4 7.6 18.0 0.16 12.2 1.4 4.5 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 PRP82543.1 - 8.7 6.7 43.6 0.52 10.7 18.5 3.1 1 1 1 2 2 2 0 Fez1 GATA PF00320.27 PRP82544.1 - 3.1e-13 49.1 3.1 3.1e-13 49.1 3.1 2.4 3 0 0 3 3 3 1 GATA zinc finger DZR PF12773.7 PRP82544.1 - 0.0086 16.1 5.0 0.054 13.5 1.1 2.5 2 0 0 2 2 2 1 Double zinc ribbon Vps36-NZF-N PF16988.5 PRP82544.1 - 4.7 6.7 5.8 0.31 10.5 0.3 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Rotamase PF00639.21 PRP82545.1 - 2.3e-22 79.7 0.3 3.9e-22 79.0 0.3 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PRP82545.1 - 1.2e-20 74.2 0.4 1.6e-20 73.8 0.4 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 PRP82545.1 - 1.1e-10 41.4 2.3 1.1e-10 41.4 2.3 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 PRP82545.1 - 0.0092 16.8 0.0 0.013 16.3 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 PRP82545.1 - 0.077 13.7 0.2 0.18 12.5 0.0 1.7 2 0 0 2 2 2 0 X8 domain 3Beta_HSD PF01073.19 PRP82546.1 - 4.3e-58 196.5 0.0 5.5e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PRP82546.1 - 1.2e-30 106.8 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP82546.1 - 2.5e-14 53.4 0.0 5.3e-11 42.5 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PRP82546.1 - 1.9e-11 44.2 0.0 3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 PRP82546.1 - 5.9e-11 42.0 0.0 7.7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PRP82546.1 - 9e-11 41.4 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 PRP82546.1 - 8.1e-06 25.2 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 PRP82546.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Auts2 PF15336.6 PRP82546.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein GAF PF01590.26 PRP82547.1 - 2.9e-42 144.5 0.0 5.1e-24 85.4 0.0 2.5 2 0 0 2 2 2 2 GAF domain Guanylate_cyc PF00211.20 PRP82547.1 - 1.2e-40 139.1 0.4 3.9e-40 137.4 0.1 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain GAF_3 PF13492.6 PRP82547.1 - 6.3e-25 88.0 0.0 3.7e-12 46.7 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 PRP82547.1 - 2.2e-24 86.3 0.0 4.4e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 GAF domain DUF3369 PF11849.8 PRP82547.1 - 6.7e-05 23.1 0.4 0.34 11.1 0.1 3.2 2 2 1 3 3 3 2 Domain of unknown function (DUF3369) PAS_9 PF13426.7 PRP82547.1 - 9e-05 22.7 0.7 0.0016 18.7 0.1 3.4 5 0 0 5 5 5 1 PAS domain PAS PF00989.25 PRP82547.1 - 9.4e-05 22.4 0.1 0.00084 19.3 0.0 2.6 2 0 0 2 2 2 1 PAS fold TPR_2 PF07719.17 PRP82547.1 - 0.0017 18.3 0.1 0.0055 16.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat dCache_1 PF02743.18 PRP82547.1 - 0.0047 16.7 1.1 0.66 9.7 0.0 3.2 3 0 0 3 3 3 1 Cache domain DUF2111 PF09884.9 PRP82547.1 - 0.11 12.6 0.1 58 3.8 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2111) CoaE PF01121.20 PRP82548.1 - 8.9e-35 120.0 2.5 8.7e-32 110.2 2.5 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.6 PRP82548.1 - 5.2e-05 23.6 0.1 0.00019 21.7 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PRP82548.1 - 0.0062 16.3 0.1 0.012 15.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 PRP82548.1 - 0.053 14.1 0.1 0.16 12.6 0.1 1.9 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 PRP82548.1 - 0.071 12.5 0.7 0.17 11.3 0.1 1.9 1 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 PRP82548.1 - 0.092 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Diphtheria_C PF02763.14 PRP82548.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, C domain GSHPx PF00255.19 PRP82549.1 - 2e-44 149.6 0.2 2.6e-44 149.2 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 PRP82549.1 - 1.2e-05 25.1 0.0 6.2e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.21 PRP82549.1 - 1.9e-05 24.6 0.0 7.1e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family RVT_1 PF00078.27 PRP82551.1 - 6.1e-19 68.4 0.2 2.2e-15 56.8 0.2 3.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GP3_package PF16677.5 PRP82554.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 DNA-packaging protein gp3 Chromo PF00385.24 PRP82555.1 - 3.3e-07 30.1 0.2 5.5e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF5341 PF17276.2 PRP82555.1 - 0.026 14.7 1.0 0.029 14.6 0.2 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5341) Rap_GAP PF02145.15 PRP82556.1 - 9.1e-21 74.2 0.0 2e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP PUL PF08324.11 PRP82556.1 - 0.00099 18.4 0.8 0.0022 17.3 0.8 1.6 1 0 0 1 1 1 1 PUL domain MFS_1 PF07690.16 PRP82558.1 - 1.1e-35 123.3 40.6 2e-33 115.8 34.5 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 PRP82558.1 - 6.7e-12 44.6 15.5 3.7e-08 32.2 5.9 2.6 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 PRP82558.1 - 1.2e-08 34.3 8.5 1.2e-08 34.3 8.5 2.9 1 1 2 3 3 3 1 Sugar (and other) transporter HlyIII PF03006.20 PRP82558.1 - 0.011 15.5 2.2 0.011 15.5 2.2 3.6 2 2 1 3 3 3 0 Haemolysin-III related OATP PF03137.20 PRP82558.1 - 3 6.0 19.9 0.0042 15.5 3.7 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SAPS PF04499.15 PRP82559.1 - 6.5e-24 84.6 1.8 3.9e-20 72.1 0.6 3.2 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein Roc PF08477.13 PRP82559.1 - 4.2e-09 36.6 0.0 1.5e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP82559.1 - 3.1e-08 33.4 0.0 6.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 PRP82559.1 - 8.3e-05 22.1 0.0 0.00018 21.0 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP82559.1 - 0.0097 16.0 0.2 0.05 13.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase RhoGAP PF00620.27 PRP82560.1 - 8.8e-32 110.0 0.0 1.9e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain SNARE_assoc PF09335.11 PRP82560.1 - 1.8e-06 28.5 1.0 1.8e-06 28.5 1.0 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein Pkinase_Tyr PF07714.17 PRP82561.1 - 1.7e-98 329.0 0.0 1e-52 179.0 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP82561.1 - 9.6e-96 320.2 0.0 4.3e-51 173.8 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Ank_2 PF12796.7 PRP82561.1 - 1.3e-16 60.9 0.0 5.4e-07 30.1 0.0 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82561.1 - 9.4e-16 58.0 0.0 1.3e-06 28.8 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP82561.1 - 4.7e-12 45.8 0.3 0.15 12.5 0.1 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 PRP82561.1 - 3.4e-09 36.8 0.1 0.00026 21.2 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) OTU PF02338.19 PRP82561.1 - 2.2e-08 34.7 0.0 7.7e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease Ank_3 PF13606.6 PRP82561.1 - 3.7e-08 33.0 0.5 4.1 8.3 0.0 6.0 4 1 1 5 5 5 1 Ankyrin repeat APH PF01636.23 PRP82561.1 - 0.00016 21.7 0.1 1.3 8.9 0.0 3.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP82561.1 - 0.042 12.8 0.0 0.042 12.8 0.0 4.1 4 0 0 4 4 4 0 Haspin like kinase domain DUF4349 PF14257.6 PRP82561.1 - 0.2 11.1 7.5 0.7 9.3 2.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) MaoC_dehydratas PF01575.19 PRP82562.1 - 1.1e-25 89.6 0.0 1.7e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 PRP82562.1 - 7.3e-05 22.9 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Pkinase PF00069.25 PRP82563.1 - 3.7e-59 200.2 0.0 6.1e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82563.1 - 7.3e-45 153.3 0.0 1.1e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 PRP82563.1 - 8.3e-17 61.1 8.4 1.6e-16 60.2 8.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 PRP82563.1 - 3.7e-08 33.8 0.0 9.8e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 PH domain FYVE_2 PF02318.16 PRP82563.1 - 5.2e-05 23.4 4.8 0.00012 22.3 4.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger Kinase-like PF14531.6 PRP82563.1 - 0.00034 20.0 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP82563.1 - 0.00056 19.3 0.1 0.0064 15.9 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP82563.1 - 0.0095 14.8 0.0 0.022 13.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PRP82563.1 - 0.028 14.3 0.1 0.26 11.2 0.0 2.5 3 1 1 4 4 4 0 Phosphotransferase enzyme family Prok-RING_4 PF14447.6 PRP82563.1 - 0.52 10.2 8.9 1.2 9.0 8.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 PRP82563.1 - 3.4 7.8 10.1 3.3 7.8 1.5 2.5 1 1 0 2 2 2 0 Double zinc ribbon Ribosomal_L16 PF00252.18 PRP82564.1 - 6e-41 139.5 0.2 8.4e-41 139.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e MMADHC PF10229.9 PRP82565.1 - 0.03 14.1 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein GSDH PF07995.11 PRP82566.1 - 9e-29 100.8 0.0 9.6e-27 94.1 0.0 2.7 2 1 0 2 2 2 2 Glucose / Sorbosone dehydrogenase PKD PF00801.20 PRP82566.1 - 7.3e-17 61.0 20.6 2.9e-12 46.3 0.4 4.4 5 0 0 5 5 5 2 PKD domain PKD_3 PF16820.5 PRP82566.1 - 0.021 14.6 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 PKD-like domain Proteasome_A_N PF10584.9 PRP82566.1 - 0.057 13.1 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Podoplanin PF05808.11 PRP82568.1 - 0.081 13.0 16.4 0.2 11.8 16.4 1.6 1 0 0 1 1 1 0 Podoplanin RNase_HII PF01351.18 PRP82569.1 - 1.8e-29 103.0 0.0 2.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease HII CH PF00307.31 PRP82569.1 - 0.15 12.3 0.0 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Calponin homology (CH) domain Abhydrolase_1 PF00561.20 PRP82571.1 - 6.3e-17 62.1 0.0 6.4e-16 58.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP82571.1 - 3e-11 43.1 0.0 3.6e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP82571.1 - 7.8e-10 39.7 0.0 9.6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 PRP82571.1 - 0.00053 20.2 0.0 0.001 19.3 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 PRP82571.1 - 0.0063 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 PRP82571.1 - 0.051 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 PRP82571.1 - 0.11 12.0 0.0 9 5.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family WD40 PF00400.32 PRP82572.1 - 2.1e-38 129.6 14.6 5.6e-07 30.2 0.1 11.2 12 0 0 12 12 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82572.1 - 1.5e-23 82.9 4.8 9.6e-05 22.6 0.0 8.7 4 2 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 PRP82572.1 - 4.7e-20 71.9 0.0 7.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 PRP82572.1 - 2e-09 36.8 1.4 0.031 13.2 0.0 5.2 5 1 1 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP82572.1 - 4.1e-08 33.3 1.8 0.27 11.1 0.0 4.4 3 1 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PRP82572.1 - 0.00072 19.0 0.9 2.6 7.3 0.0 4.0 3 1 0 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 PRP82572.1 - 0.01 14.6 1.7 1.6 7.4 0.0 3.9 4 1 1 5 5 5 0 Nup133 N terminal like PD40 PF07676.12 PRP82572.1 - 0.023 14.6 0.3 20 5.3 0.1 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Kelch_6 PF13964.6 PRP82572.1 - 0.025 14.9 1.0 5.7 7.4 0.1 3.8 3 0 0 3 3 3 0 Kelch motif Syncollin PF15138.6 PRP82572.1 - 0.054 13.7 0.0 0.24 11.6 0.0 2.1 1 0 0 1 1 1 0 Syncollin Nup160 PF11715.8 PRP82572.1 - 0.085 11.5 1.0 0.56 8.8 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 RRM_1 PF00076.22 PRP82572.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 PRP82572.1 - 0.95 7.7 24.8 1.3 7.2 24.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 PRP82572.1 - 1.2 7.3 33.9 1.7 6.8 33.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 PRP82572.1 - 1.5 8.2 37.4 2.3 7.5 37.4 1.2 1 0 0 1 1 1 0 SDA1 Ribosomal_L18A PF01775.17 PRP82573.1 - 6.3e-46 155.4 0.1 8.2e-46 155.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A WD40 PF00400.32 PRP82574.1 - 1.9e-31 107.6 4.0 4.4e-05 24.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82574.1 - 1.3e-16 60.7 0.2 0.037 14.3 0.0 5.6 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain CSTF1_dimer PF16699.5 PRP82574.1 - 3.1e-06 26.9 0.0 1.6e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain eIF2A PF08662.11 PRP82574.1 - 0.00024 21.1 2.4 1.9 8.3 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PRP82574.1 - 0.00082 18.4 0.3 0.043 12.8 0.0 3.4 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PRP82574.1 - 0.00095 17.8 0.1 0.3 9.5 0.1 3.1 2 1 2 4 4 4 2 Cytochrome D1 heme domain VID27 PF08553.10 PRP82574.1 - 0.0045 16.1 0.0 0.042 12.9 0.0 2.5 3 1 1 4 4 4 1 VID27 C-terminal WD40-like domain Frtz PF11768.8 PRP82574.1 - 0.14 10.5 0.0 0.27 9.5 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz G-alpha PF00503.20 PRP82575.1 - 2.9e-111 372.0 6.8 3.6e-111 371.7 6.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PRP82575.1 - 3.3e-13 49.5 0.4 2.3e-09 36.9 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 PRP82575.1 - 0.027 14.7 1.8 7.5 6.8 0.0 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 PRP82575.1 - 0.039 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_15 PF13175.6 PRP82575.1 - 0.051 13.3 2.2 0.1 12.3 0.4 2.2 2 1 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 PRP82575.1 - 0.055 12.9 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Gtr1_RagA PF04670.12 PRP82575.1 - 0.073 12.4 2.6 1.1 8.6 0.3 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 PRP82575.1 - 0.1 12.3 0.0 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NAD_synthase PF02540.17 PRP82576.1 - 1e-34 119.8 0.0 1.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 NAD synthase ATP_bind_3 PF01171.20 PRP82576.1 - 0.074 12.8 1.0 0.23 11.2 0.3 1.9 1 1 1 2 2 2 0 PP-loop family Asn_synthase PF00733.21 PRP82576.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.16 PRP82576.1 - 0.12 11.2 0.1 0.21 10.3 0.1 1.4 1 0 0 1 1 1 0 tRNA methyl transferase Sacchrp_dh_NADP PF03435.18 PRP82576.1 - 0.15 12.4 0.1 0.43 10.8 0.1 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain QueC PF06508.13 PRP82576.1 - 0.21 11.1 0.5 1 8.8 0.5 2.2 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC MFS_1 PF07690.16 PRP82578.1 - 1.5e-45 155.7 24.0 1.5e-45 155.7 24.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Chal_sti_synt_N PF00195.19 PRP82578.1 - 0.084 12.3 0.1 0.55 9.6 0.0 1.9 2 0 0 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain NmrA PF05368.13 PRP82579.1 - 7.4e-65 218.8 0.1 9.1e-65 218.5 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP82579.1 - 8.6e-20 71.4 0.1 1.1e-19 71.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PRP82579.1 - 2.3e-07 30.5 0.0 4.7e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PRP82579.1 - 5.7e-07 28.8 0.0 7.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 PRP82579.1 - 3.6e-05 24.0 0.1 7.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 PRP82579.1 - 7.7e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 PRP82579.1 - 0.00085 19.7 0.1 0.0022 18.4 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 PRP82579.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 PRP82579.1 - 0.0048 17.0 0.0 0.0089 16.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Anoctamin PF04547.12 PRP82580.1 - 9.3e-124 413.7 10.2 1.4e-123 413.1 10.2 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PRP82580.1 - 1.8e-10 40.9 0.0 6.2e-09 35.9 0.0 2.8 2 1 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin TCR PF03638.15 PRP82581.1 - 0.0022 18.2 22.7 0.0041 17.4 22.7 1.5 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain VESA1_N PF12785.7 PRP82581.1 - 0.46 9.4 10.7 0.58 9.1 10.7 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 WD40 PF00400.32 PRP82583.1 - 8.1e-10 39.1 13.4 0.019 15.8 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82583.1 - 1.6e-08 34.7 5.7 0.29 11.5 0.0 6.6 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 PRP82583.1 - 0.00039 19.6 1.0 0.16 11.0 0.0 3.5 2 1 1 3 3 3 2 Coatomer WD associated region eIF2A PF08662.11 PRP82583.1 - 0.002 18.0 4.4 0.047 13.6 0.0 4.2 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 PRP82583.1 - 0.0024 16.0 0.0 0.093 10.7 0.0 2.6 2 1 0 2 2 2 1 IKI3 family PglD_N PF17836.1 PRP82583.1 - 0.052 14.2 0.3 1.6 9.4 0.1 2.6 2 0 0 2 2 2 0 PglD N-terminal domain Tachylectin PF14517.6 PRP82583.1 - 0.11 12.0 3.4 0.59 9.6 0.1 3.0 2 1 0 3 3 3 0 Tachylectin PRD PF00874.20 PRP82584.1 - 0.12 12.7 5.4 0.21 11.9 0.9 2.3 2 0 0 2 2 2 0 PRD domain Sof1 PF04158.14 PRP82584.1 - 0.33 11.3 9.8 2.2 8.6 1.0 2.7 1 1 1 2 2 2 0 Sof1-like domain FliJ PF02050.16 PRP82584.1 - 0.43 10.8 8.0 0.42 10.8 2.4 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Jnk-SapK_ap_N PF09744.9 PRP82584.1 - 0.46 10.7 9.8 0.12 12.5 1.6 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 PRP82584.1 - 0.84 10.3 0.0 0.84 10.3 0.0 3.3 4 1 0 4 4 4 0 SlyX ARF7EP_C PF14949.6 PRP82584.1 - 6.3 7.5 6.3 0.6 10.7 0.5 2.2 3 0 0 3 3 3 0 ARF7 effector protein C-terminus DUF778 PF05608.12 PRP82585.1 - 2.7e-30 106.2 2.8 1.8e-15 57.9 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Collagen PF01391.18 PRP82585.1 - 0.026 14.3 3.4 0.04 13.7 3.4 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) NfrA_C PF13283.6 PRP82585.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Cuticle_3 PF11018.8 PRP82586.1 - 0.0043 17.3 11.0 0.007 16.6 11.0 1.3 1 0 0 1 1 1 1 Pupal cuticle protein C1 PARP PF00644.20 PRP82587.1 - 2.5e-62 210.0 0.0 5.5e-62 208.8 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PRP82587.1 - 3.9e-39 133.9 1.4 7.9e-39 132.9 1.4 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 PRP82587.1 - 1.2e-17 63.7 3.2 8.5e-17 61.0 0.2 3.0 2 0 0 2 2 2 1 WGR domain PADR1 PF08063.12 PRP82587.1 - 1.7e-15 56.5 0.1 1.7e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 PADR1 (NUC008) domain zf-PARP PF00645.18 PRP82587.1 - 3.1e-13 50.4 0.1 3.1e-13 50.4 0.1 2.8 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region BRCT PF00533.26 PRP82587.1 - 3.8e-12 46.4 0.1 1.2e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP82587.1 - 7.8e-10 39.0 0.1 2.3e-09 37.5 0.1 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PRP82587.1 - 0.019 14.9 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 twin BRCT domain MerR_1 PF13411.6 PRP82587.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein CEP44 PF15007.6 PRP82588.1 - 2.6e-08 34.1 0.1 3.4e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Zn_ribbon_17 PF17120.5 PRP82588.1 - 0.05 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type NMD3 PF04981.13 PRP82588.1 - 0.052 13.0 0.0 0.067 12.6 0.0 1.1 1 0 0 1 1 1 0 NMD3 family MoaF PF10703.9 PRP82588.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 MoaF N-terminal domain PKD PF00801.20 PRP82589.1 - 4.1e-20 71.4 7.0 4.8e-09 35.9 0.4 4.2 4 0 0 4 4 4 2 PKD domain GSDH PF07995.11 PRP82589.1 - 2e-19 70.1 0.0 2.8e-17 63.1 0.0 3.1 2 2 0 2 2 2 2 Glucose / Sorbosone dehydrogenase Exo_endo_phos PF03372.23 PRP82590.1 - 2.6e-23 82.8 0.0 4.6e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 PRP82590.1 - 1.5e-17 63.6 15.9 2.5e-09 37.6 0.1 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat TLE_N PF03920.15 PRP82590.1 - 7e-07 29.4 5.4 1.7e-06 28.1 5.4 1.7 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain ANAPC4_WD40 PF12894.7 PRP82590.1 - 0.0034 17.6 0.1 4.5 7.6 0.0 3.6 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain NYD-SP28_assoc PF14775.6 PRP82590.1 - 0.0099 16.0 0.6 0.0099 16.0 0.6 2.8 3 0 0 3 3 3 1 Sperm tail C-terminal domain ZapB PF06005.12 PRP82590.1 - 0.016 15.6 2.5 0.054 13.9 2.5 1.8 1 0 0 1 1 1 0 Cell division protein ZapB KxDL PF10241.9 PRP82590.1 - 0.037 14.3 2.1 0.16 12.2 2.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein Nup160 PF11715.8 PRP82590.1 - 0.068 11.8 0.0 2.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 PRP82590.1 - 0.084 12.2 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 PRP82590.1 - 0.1 11.6 0.0 0.34 9.8 0.0 1.8 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATG27 PF09451.10 PRP82591.1 - 0.0031 17.4 0.1 0.084 12.7 0.0 2.2 2 0 0 2 2 2 2 Autophagy-related protein 27 ABC_membrane PF00664.23 PRP82593.1 - 2e-69 234.3 25.3 2.2e-38 132.5 10.7 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP82593.1 - 1.8e-53 180.8 0.0 4e-30 105.1 0.1 3.1 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PRP82593.1 - 3.8e-10 39.6 0.8 0.003 17.0 0.1 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PRP82593.1 - 1.4e-07 31.6 0.2 0.018 15.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_ATPase PF09818.9 PRP82593.1 - 7.1e-06 25.1 0.7 0.00077 18.4 0.1 2.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 PRP82593.1 - 4.8e-05 23.3 0.1 0.044 13.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 PRP82593.1 - 6.2e-05 22.7 0.7 0.18 11.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PRP82593.1 - 0.001 19.3 4.6 0.87 9.9 0.0 4.1 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 PRP82593.1 - 0.017 14.7 1.0 0.29 10.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP82593.1 - 0.027 14.2 3.6 0.97 9.1 0.3 3.0 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 PRP82593.1 - 0.029 14.4 0.3 0.029 14.4 0.3 4.2 3 1 0 3 3 2 0 Dynamin family Ploopntkinase3 PF18751.1 PRP82593.1 - 0.045 13.7 0.2 4.6 7.1 0.0 2.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 PRP82593.1 - 0.11 12.2 0.2 5.4 6.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 PRP82593.1 - 0.12 11.3 0.6 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 PRP82593.1 - 0.24 10.9 1.6 22 4.5 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_16 PF13191.6 PRP82593.1 - 0.34 11.3 12.0 0.42 11.0 0.1 3.8 3 1 0 3 3 2 0 AAA ATPase domain RR_TM4-6 PF06459.12 PRP82593.1 - 0.7 9.7 28.7 1.8 8.3 26.4 2.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 cobW PF02492.19 PRP82593.1 - 0.74 9.4 3.1 1.8 8.1 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 PRP82593.1 - 0.89 10.0 0.0 0.89 10.0 0.0 4.5 3 1 0 3 3 2 0 AAA domain AAA_21 PF13304.6 PRP82593.1 - 5.7 6.7 20.7 0.91 9.3 0.0 5.0 5 1 1 6 6 5 0 AAA domain, putative AbiEii toxin, Type IV TA system SAPS PF04499.15 PRP82593.1 - 9 4.9 19.3 20 3.8 19.3 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4366 PF14283.6 PRP82594.1 - 0.0082 16.2 1.1 0.0082 16.2 1.1 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4366) SKG6 PF08693.10 PRP82594.1 - 0.014 14.8 0.1 0.03 13.7 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 PRP82594.1 - 0.13 12.2 0.6 0.33 10.9 0.6 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif IF-2B PF01008.17 PRP82595.1 - 1.2e-67 228.1 0.0 1.4e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Rbsn PF11464.8 PRP82595.1 - 0.14 11.9 0.4 1 9.1 0.0 2.6 3 0 0 3 3 3 0 Rabenosyn Rab binding domain AA_permease PF00324.21 PRP82596.1 - 5.3e-102 341.9 47.3 6.3e-102 341.6 47.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 PRP82596.1 - 1.4e-30 106.5 52.3 1.9e-30 106.1 52.3 1.2 1 0 0 1 1 1 1 Amino acid permease TPK_catalytic PF04263.16 PRP82597.1 - 4.5e-28 97.7 0.0 1e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain Pectate_lyase_3 PF12708.7 PRP82597.1 - 1.1e-17 64.7 1.5 1.1e-17 64.7 1.5 2.6 1 1 1 2 2 2 1 Pectate lyase superfamily protein TPK_B1_binding PF04265.14 PRP82597.1 - 1e-15 57.2 0.0 2.6e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Beta_helix PF13229.6 PRP82597.1 - 3.4e-13 49.7 17.9 4.7e-08 33.0 1.8 2.7 2 1 2 4 4 4 3 Right handed beta helix region ZnuA PF01297.17 PRP82597.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Hydrolase_2 PF07486.12 PRP82598.1 - 4.7e-08 33.8 3.3 0.00085 20.1 0.2 3.0 2 1 1 3 3 3 2 Cell Wall Hydrolase zf-C2H2_2 PF12756.7 PRP82600.1 - 0.00025 21.3 4.3 0.00025 21.3 4.3 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 PRP82600.1 - 0.00061 20.4 0.5 0.0018 19.0 0.5 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger MULE PF10551.9 PRP82600.1 - 0.096 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 MULE transposase domain zf-C2H2_jaz PF12171.8 PRP82600.1 - 2.5 8.5 11.3 0.44 10.9 7.0 2.1 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding F-box-like PF12937.7 PRP82601.1 - 1.2e-11 44.3 0.1 2.3e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP82601.1 - 9.8e-11 41.3 0.3 1.7e-10 40.5 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP82601.1 - 0.00039 20.3 0.6 0.00066 19.5 0.1 1.7 2 0 0 2 2 2 1 F-box SPRY PF00622.28 PRP82601.1 - 0.0037 17.4 0.0 0.023 14.8 0.1 2.0 2 0 0 2 2 2 1 SPRY domain Herpes_Helicase PF02689.14 PRP82601.1 - 0.18 9.7 0.0 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Helicase Synaptobrevin PF00957.21 PRP82602.1 - 2.8e-23 81.5 1.2 4.8e-23 80.8 1.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Topoisom_I_N PF02919.15 PRP82603.1 - 2e-86 288.9 3.4 2e-86 288.9 3.4 3.9 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 PRP82603.1 - 3.1e-66 222.9 21.1 3.8e-64 216.1 15.4 3.6 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 PRP82603.1 - 5.5e-32 109.5 1.8 5.5e-32 109.5 1.8 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain FlxA PF14282.6 PRP82603.1 - 0.00011 22.1 6.4 0.00011 22.1 6.4 6.5 6 1 0 7 7 7 1 FlxA-like protein DUF4732 PF15876.5 PRP82604.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) Pex2_Pex12 PF04757.14 PRP82606.1 - 6.8e-43 146.8 6.9 8.3e-43 146.6 6.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 PRP82606.1 - 0.066 13.1 2.7 0.13 12.2 2.7 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP82606.1 - 8.1 6.9 6.7 40 4.7 6.7 2.0 1 1 1 2 2 2 0 Ring finger domain Ank_2 PF12796.7 PRP82607.1 - 6.7e-52 174.0 0.0 2.4e-10 40.9 0.0 7.3 2 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP82607.1 - 4.4e-35 119.6 3.9 0.00046 20.7 0.0 10.6 3 2 9 12 12 12 9 Ankyrin repeats (many copies) Las1 PF04031.13 PRP82607.1 - 1e-26 93.9 0.1 3.6e-26 92.1 0.1 2.0 1 0 0 1 1 1 1 Las1-like Ank_5 PF13857.6 PRP82607.1 - 5.1e-26 90.4 5.2 0.099 13.0 0.0 12.9 5 5 8 13 13 13 8 Ankyrin repeats (many copies) Ank PF00023.30 PRP82607.1 - 2.8e-24 84.4 12.7 0.33 11.5 0.0 13.9 11 4 1 12 12 12 7 Ankyrin repeat Ank_3 PF13606.6 PRP82607.1 - 1.4e-22 77.3 3.4 7.1 7.6 0.0 15.1 16 0 0 16 16 16 4 Ankyrin repeat YlzJ PF14035.6 PRP82607.1 - 0.00098 19.3 0.1 44 4.4 0.0 5.9 6 0 0 6 6 6 0 YlzJ-like protein V-ATPase_H_C PF11698.8 PRP82607.1 - 0.076 13.1 0.1 0.28 11.3 0.1 2.0 1 0 0 1 1 1 0 V-ATPase subunit H PH PF00169.29 PRP82608.1 - 5.4e-25 87.9 0.0 4e-12 46.6 0.0 3.4 2 0 0 2 2 2 2 PH domain CH PF00307.31 PRP82608.1 - 2.9e-20 72.5 0.0 9.5e-20 70.8 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP82608.1 - 0.0032 17.3 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain PP2C PF00481.21 PRP82609.1 - 5e-60 203.3 0.0 9.6e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PRP82609.1 - 0.0012 18.6 0.2 0.005 16.5 0.2 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Peptidase_M90 PF06167.12 PRP82612.1 - 0.0048 16.5 0.0 4.3 6.9 0.0 2.6 2 1 0 2 2 2 2 Glucose-regulated metallo-peptidase M90 Peptidase_M66 PF10462.9 PRP82612.1 - 0.27 10.1 3.3 6.3 5.7 0.1 2.4 2 0 0 2 2 2 0 Peptidase M66 DENN PF02141.21 PRP82613.1 - 2.2e-19 70.2 3.4 1.5e-18 67.4 3.4 2.1 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PRP82613.1 - 4.8e-10 40.0 2.0 1.2e-08 35.6 0.0 3.3 3 0 0 3 3 3 1 uDENN domain DUF1697 PF08002.11 PRP82613.1 - 0.057 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) dDENN PF03455.19 PRP82613.1 - 0.086 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 dDENN domain CorC_HlyC PF03471.17 PRP82613.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Transporter associated domain Pentapeptide_2 PF01469.18 PRP82614.1 - 0.0028 17.5 10.6 0.0071 16.2 10.6 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) DUF1180 PF06679.12 PRP82614.1 - 1.7 9.0 6.9 4 7.8 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Lactamase_B PF00753.27 PRP82615.1 - 5.7e-22 78.7 0.2 8.4e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 PRP82615.1 - 1.7e-16 59.9 0.2 3.3e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 PRP82615.1 - 0.0016 18.0 0.1 0.0029 17.2 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF5617 PF18493.1 PRP82615.1 - 0.099 12.8 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) Lactamase_B_3 PF13483.6 PRP82615.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain RRM_1 PF00076.22 PRP82616.1 - 2e-35 120.4 0.1 5.7e-13 48.5 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP82616.1 - 0.00029 20.9 0.0 0.0037 17.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 PRP82616.1 - 0.00078 19.3 0.0 13 5.8 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 PRP82616.1 - 0.0019 17.8 0.0 2.5 7.7 0.0 3.6 2 2 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 PRP82616.1 - 0.038 14.2 0.0 6.5 7.0 0.0 2.7 1 1 1 2 2 2 0 RRM-like domain Rad60-SLD PF11976.8 PRP82617.1 - 2.2e-19 69.0 0.3 1.1e-12 47.6 0.5 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PRP82617.1 - 2.2e-06 27.3 0.3 0.00098 18.8 0.2 2.2 2 0 0 2 2 2 2 Ubiquitin family WD40 PF00400.32 PRP82618.1 - 8.5e-27 92.9 13.6 9.6e-05 23.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82618.1 - 4.9e-06 26.8 0.9 3 8.2 0.0 4.6 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP82618.1 - 0.0009 19.2 2.6 1.7 8.4 0.0 3.4 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PRP82618.1 - 0.011 14.5 3.8 0.42 9.2 0.0 3.7 1 1 2 4 4 4 0 Nucleoporin Nup120/160 Cystatin PF00031.21 PRP82622.1 - 1.1e-05 25.6 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Cystatin domain AT_hook PF02178.19 PRP82623.1 - 0.00069 19.2 71.7 0.018 14.8 4.8 6.3 6 0 0 6 6 6 4 AT hook motif EI24 PF07264.11 PRP82624.1 - 3.5e-09 37.1 10.5 1.9e-08 34.8 11.1 1.8 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DUF2207 PF09972.9 PRP82624.1 - 0.17 10.6 6.1 0.65 8.7 6.1 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Hpt PF01627.23 PRP82625.1 - 4.3e-06 26.9 0.0 8.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Hpt domain Macoilin PF09726.9 PRP82625.1 - 0.4 9.2 6.3 0.44 9.1 6.3 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 PRP82625.1 - 2.7 6.6 6.8 3.8 6.1 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 PRP82625.1 - 4 6.1 9.7 4.8 5.9 9.7 1.1 1 0 0 1 1 1 0 Presenilin INTS5_C PF14838.6 PRP82626.1 - 3.9e-15 55.6 1.2 1e-14 54.2 0.0 2.2 2 1 1 3 3 3 1 Integrator complex subunit 5 C-terminus INTS5_N PF14837.6 PRP82626.1 - 3.6e-08 33.3 0.0 1.4e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus DEAD PF00270.29 PRP82627.1 - 3e-20 72.7 0.1 5.5e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP82627.1 - 9.2e-07 29.0 0.0 3.4e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP82627.1 - 0.046 14.1 0.0 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 Helicase conserved C-terminal domain FliG_N PF14842.6 PRP82627.1 - 0.064 13.8 0.3 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 FliG N-terminal domain DivIC PF04977.15 PRP82627.1 - 0.55 10.0 5.7 0.31 10.8 2.6 2.1 2 0 0 2 2 2 0 Septum formation initiator HGTP_anticodon PF03129.20 PRP82627.1 - 0.92 9.7 3.1 5.7 7.2 0.0 3.2 3 1 0 3 3 3 0 Anticodon binding domain APG6_N PF17675.1 PRP82627.1 - 4.7 7.7 9.3 2.7 8.5 4.6 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 PRP82627.1 - 9.6 6.4 9.8 1.8 8.7 1.0 2.8 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PRA1 PF03208.19 PRP82628.1 - 3.5e-26 91.6 0.3 5.6e-26 90.9 0.3 1.3 1 0 0 1 1 1 1 PRA1 family protein CUE PF02845.16 PRP82628.1 - 0.045 13.5 0.3 0.091 12.5 0.3 1.6 1 0 0 1 1 1 0 CUE domain EcsB PF05975.12 PRP82628.1 - 0.23 10.3 3.9 0.97 8.2 4.3 1.7 1 1 1 2 2 2 0 Bacterial ABC transporter protein EcsB AFG1_ATPase PF03969.16 PRP82629.1 - 1.9e-55 188.2 4.8 2.8e-54 184.4 4.0 2.6 2 1 0 2 2 2 1 AFG1-like ATPase PEPCK_ATP PF01293.20 PRP82629.1 - 1.1e-14 54.0 0.0 6.9e-11 41.5 0.0 2.8 2 1 0 2 2 2 2 Phosphoenolpyruvate carboxykinase ATPase_2 PF01637.18 PRP82629.1 - 6.3e-06 26.3 0.2 3.7e-05 23.7 0.0 2.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 PRP82629.1 - 1.2e-05 25.6 0.1 6e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 PRP82629.1 - 2.3e-05 24.8 0.0 0.00011 22.6 0.0 2.2 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 PRP82629.1 - 0.00014 21.9 0.0 0.00036 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP82629.1 - 0.00045 20.6 0.1 0.006 17.0 0.1 2.6 2 1 0 2 2 1 1 AAA ATPase domain Bac_DnaA PF00308.18 PRP82629.1 - 0.0014 18.5 0.2 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein RLAN PF14401.6 PRP82629.1 - 0.0022 17.7 0.1 0.047 13.3 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATPgrasp N-terminal domain TniB PF05621.11 PRP82629.1 - 0.0028 17.1 0.1 0.0056 16.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial TniB protein AAA_5 PF07728.14 PRP82629.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 PRP82629.1 - 0.012 15.6 0.0 0.039 13.9 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 PRP82629.1 - 0.017 14.3 0.4 0.063 12.4 0.4 2.0 1 1 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 PRP82629.1 - 0.054 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 PRP82629.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 PRP82629.1 - 0.11 12.9 0.0 0.43 11.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase DUF4145 PF13643.6 PRP82629.1 - 0.13 12.4 0.1 2.9 8.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) DUF1848 PF08902.11 PRP82629.1 - 0.44 10.2 1.2 0.65 9.7 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1848) Folate_rec PF03024.14 PRP82630.1 - 6.1e-09 36.0 7.8 1.3e-08 34.9 7.8 1.5 1 0 0 1 1 1 1 Folate receptor family CBM_2 PF00553.19 PRP82630.1 - 0.013 15.8 0.2 0.025 14.9 0.2 1.4 1 0 0 1 1 1 0 Cellulose binding domain NTP_transferase PF00483.23 PRP82631.1 - 6.4e-49 166.8 0.0 8.5e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 PRP82631.1 - 3.8e-11 42.2 8.3 1.1e-08 34.4 3.2 3.2 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 PRP82631.1 - 2e-09 38.0 0.0 2.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 PRP82631.1 - 1.2e-05 24.9 1.1 1.2e-05 24.9 1.1 3.1 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 PRP82631.1 - 0.032 12.4 0.4 0.064 11.4 0.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 PRP82631.1 - 0.052 12.5 0.0 0.46 9.4 0.0 2.1 2 0 0 2 2 2 0 L-fucokinase Arm PF00514.23 PRP82632.1 - 3.6e-89 290.4 10.0 3.1e-13 49.3 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PRP82632.1 - 7.5e-20 71.1 0.1 3.3e-06 27.4 0.0 5.7 2 1 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 PRP82632.1 - 2.2e-19 69.6 0.1 1.5e-06 28.6 0.0 4.7 3 1 1 4 4 4 4 HEAT-like repeat Arm_3 PF16186.5 PRP82632.1 - 9.1e-19 66.8 1.6 1.8e-18 65.8 1.6 1.5 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 PRP82632.1 - 9.7e-14 51.6 2.9 2.5e-13 50.3 2.9 1.7 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.22 PRP82632.1 - 2.9e-13 48.8 0.1 0.0026 17.9 0.0 8.0 8 0 0 8 8 8 1 HEAT repeat Arm_2 PF04826.13 PRP82632.1 - 7.5e-07 28.9 0.0 0.043 13.3 0.0 3.0 2 1 1 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.8 PRP82632.1 - 7.3e-06 26.1 0.0 0.16 12.1 0.0 4.3 4 0 0 4 4 4 1 V-ATPase subunit H Cnd1 PF12717.7 PRP82632.1 - 2.7e-05 24.2 0.0 0.44 10.6 0.0 3.3 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PRP82632.1 - 0.00027 19.6 0.0 0.023 13.3 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region RICTOR_V PF14668.6 PRP82632.1 - 0.044 14.0 0.5 5.8 7.2 0.0 3.8 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Mo25 PF08569.11 PRP82632.1 - 0.049 13.0 0.1 0.41 10.0 0.0 2.1 1 1 0 2 2 2 0 Mo25-like Atx10homo_assoc PF09759.9 PRP82632.1 - 0.059 13.4 0.4 1.6 8.8 0.0 2.9 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 PRP82632.1 - 0.079 13.7 0.1 13 6.8 0.0 4.3 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Gcn1_N PF12074.8 PRP82632.1 - 0.15 11.3 0.8 4.9 6.3 0.0 2.8 3 0 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Nipped-B_C PF12830.7 PRP82632.1 - 0.55 10.1 3.1 11 5.9 0.1 3.2 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus SEP PF08059.13 PRP82633.1 - 1.2e-09 38.6 0.0 2.7e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 PRP82633.1 - 7.7e-08 32.4 0.0 2.7e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 UBX domain DUF1640 PF07798.11 PRP82633.1 - 0.051 13.6 4.1 0.091 12.8 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Bul1_C PF04426.12 PRP82633.1 - 0.055 12.9 1.6 0.089 12.2 1.6 1.2 1 0 0 1 1 1 0 Bul1 C terminus Fmp27_WPPW PF10359.9 PRP82633.1 - 0.074 11.9 2.6 0.11 11.4 2.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DSPc PF00782.20 PRP82634.1 - 5.2e-14 52.2 0.1 9.3e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP82634.1 - 3.2e-05 23.6 0.2 7.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 PRP82634.1 - 0.012 14.6 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Pectate_lyase_3 PF12708.7 PRP82635.1 - 3.8e-89 298.2 14.6 2.6e-77 259.5 2.9 3.6 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 PRP82635.1 - 1.7e-05 24.4 0.3 0.16 11.6 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Carb_bind PF10645.9 PRP82635.1 - 0.063 13.5 18.3 0.028 14.6 3.0 3.1 2 0 0 2 2 2 0 Carbohydrate binding GTP_EFTU PF00009.27 PRP82636.1 - 2.5e-36 125.1 0.0 5.3e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PRP82636.1 - 7.8e-20 71.3 1.5 9.6e-20 71.0 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PRP82636.1 - 2.5e-05 24.6 0.2 6.3e-05 23.3 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 HBS1_N PF08938.10 PRP82636.1 - 0.00016 21.9 1.0 0.00038 20.7 1.0 1.7 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 PRP82636.1 - 0.00017 21.6 0.0 0.00043 20.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 PRP82636.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Septin UBA PF00627.31 PRP82636.1 - 0.0057 16.5 0.5 0.012 15.5 0.5 1.6 1 0 0 1 1 1 1 UBA/TS-N domain GTP_EFTU_D4 PF14578.6 PRP82636.1 - 0.013 15.4 0.2 0.032 14.1 0.2 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 UBA_4 PF14555.6 PRP82636.1 - 0.035 13.9 0.5 0.086 12.7 0.5 1.6 1 0 0 1 1 1 0 UBA-like domain SRPRB PF09439.10 PRP82636.1 - 0.037 13.5 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Draxin PF15550.6 PRP82636.1 - 0.68 9.7 4.9 1.1 9.1 4.9 1.2 1 0 0 1 1 1 0 Draxin Pkinase_Tyr PF07714.17 PRP82637.1 - 2.8e-72 243.1 0.0 3.9e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82637.1 - 1e-49 169.3 0.0 1.5e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP82637.1 - 1.2e-36 124.3 95.2 6.2e-12 45.1 3.2 13.9 10 3 4 14 14 14 8 Leucine rich repeat LRR_4 PF12799.7 PRP82637.1 - 2.1e-33 113.8 99.8 6.3e-06 26.4 0.0 18.3 12 3 2 18 18 18 8 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP82637.1 - 4.1e-07 29.5 82.3 2 8.7 0.1 20.9 22 0 0 22 22 22 5 Leucine Rich repeat Kinase-like PF14531.6 PRP82637.1 - 3.9e-05 23.1 0.0 8.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP82637.1 - 0.0011 17.9 0.0 0.0017 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP82637.1 - 0.0054 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_1 PF00560.33 PRP82637.1 - 0.015 15.8 90.7 2.4 9.0 0.0 23.1 23 4 1 24 24 22 0 Leucine Rich Repeat Haspin_kinase PF12330.8 PRP82637.1 - 0.015 14.2 0.2 0.048 12.6 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain LRR_9 PF14580.6 PRP82637.1 - 1.6 8.2 24.0 3.6 7.1 0.2 6.3 5 2 2 7 7 7 0 Leucine-rich repeat Sds3 PF08598.11 PRP82638.1 - 4.2e-23 82.5 19.4 3.4e-21 76.2 18.0 2.3 1 1 1 2 2 2 2 Sds3-like PTPRCAP PF15713.5 PRP82638.1 - 2.5 8.4 17.6 1.4 9.2 10.7 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SAP PF02037.27 PRP82639.1 - 3.3e-11 42.7 1.3 7.5e-11 41.5 1.3 1.7 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 PRP82639.1 - 5.6e-05 22.9 23.3 0.00016 21.4 2.0 4.1 2 1 1 4 4 4 3 Tho1/MOS11 C-terminal domain DIMCO_N PF16844.5 PRP82639.1 - 0.087 13.2 0.6 0.087 13.2 0.6 2.4 2 1 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Ribosomal_L29 PF00831.23 PRP82640.1 - 3.7e-17 62.0 0.6 3.7e-17 62.0 0.6 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein EVC2_like PF12297.8 PRP82640.1 - 0.017 13.8 2.5 0.017 13.8 1.1 1.6 1 1 1 2 2 2 0 Ellis van Creveld protein 2 like protein Vps54_N PF10475.9 PRP82640.1 - 0.017 14.4 6.2 0.02 14.2 6.2 1.0 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex MRP-L47 PF06984.13 PRP82640.1 - 0.99 9.6 3.7 1.5 9.0 1.0 2.5 2 2 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Pep3_Vps18 PF05131.14 PRP82641.1 - 3.4e-41 140.5 0.3 2.3e-40 137.8 0.1 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 PRP82641.1 - 4.7e-13 49.2 18.5 5.5e-12 45.8 4.9 3.6 2 1 2 4 4 4 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 PRP82641.1 - 0.00019 21.3 2.5 0.0012 18.7 0.5 2.6 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PRP82641.1 - 0.0018 17.9 0.2 0.0044 16.6 0.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 PRP82641.1 - 0.0044 16.7 2.6 0.013 15.2 2.6 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PRP82641.1 - 0.0092 15.8 1.6 0.0092 15.8 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 PRP82641.1 - 0.014 15.9 1.3 0.044 14.2 0.1 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 PRP82641.1 - 0.016 15.5 2.8 0.029 14.7 0.8 2.3 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.7 PRP82641.1 - 0.026 14.8 2.2 0.077 13.3 0.6 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP82641.1 - 0.041 13.9 0.5 0.11 12.5 0.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 PRP82641.1 - 0.14 12.3 0.6 0.79 9.8 0.1 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_7 PF13176.6 PRP82641.1 - 0.15 12.2 0.2 32 4.9 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 PRP82641.1 - 0.15 11.9 2.5 2.5 8.0 0.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PRP82641.1 - 0.22 11.4 4.4 0.069 13.0 0.7 2.2 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 PRP82641.1 - 0.26 11.5 3.8 75 3.8 0.0 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat CCG PF02754.16 PRP82641.1 - 2.5 8.4 4.5 1.2 9.4 0.1 2.7 3 0 0 3 3 3 0 Cysteine-rich domain Fer4_22 PF17179.4 PRP82641.1 - 4.1 8.3 8.1 26 5.8 0.1 3.1 3 0 0 3 3 2 0 4Fe-4S dicluster domain Pkinase PF00069.25 PRP82642.1 - 3.3e-31 108.6 0.0 5.5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DNA_pol_A_exo1 PF01612.20 PRP82642.1 - 1.3e-13 51.1 0.0 3.1e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 3'-5' exonuclease Pkinase_Tyr PF07714.17 PRP82642.1 - 9.9e-13 48.0 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP82642.1 - 2.5e-07 30.3 0.0 4.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-CCCH_4 PF18044.1 PRP82642.1 - 0.00029 20.5 4.6 0.00075 19.2 4.6 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 PRP82642.1 - 0.00051 20.7 0.0 0.0018 19.0 0.0 1.9 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 PRP82642.1 - 0.00082 19.3 5.6 0.0016 18.4 5.6 1.5 1 0 0 1 1 1 1 Zinc finger domain APH PF01636.23 PRP82642.1 - 0.0024 17.8 0.1 0.0057 16.6 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-CCCH PF00642.24 PRP82642.1 - 0.0058 16.5 6.7 0.013 15.4 6.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Choline_kinase PF01633.20 PRP82642.1 - 0.032 13.8 0.0 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase ParB PF08775.10 PRP82642.1 - 0.15 12.5 0.2 2.1 8.9 0.1 2.4 2 0 0 2 2 2 0 ParB family TFIIA PF03153.13 PRP82642.1 - 0.39 10.6 17.2 0.29 11.1 10.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DHR10 PF18595.1 PRP82643.1 - 0.00032 20.7 10.3 0.00032 20.7 10.3 5.7 5 2 1 6 6 6 1 Designed helical repeat protein 10 domain Filament PF00038.21 PRP82643.1 - 0.0059 16.2 4.1 0.0059 16.2 4.1 4.8 3 1 2 5 5 5 2 Intermediate filament protein FCD PF07729.12 PRP82643.1 - 0.026 15.0 0.1 17 5.9 0.0 3.1 2 0 0 2 2 2 0 FCD domain ZapB PF06005.12 PRP82643.1 - 0.15 12.5 39.6 1.4 9.4 8.9 5.6 4 1 1 5 5 5 0 Cell division protein ZapB Hema_stalk PF08720.10 PRP82643.1 - 0.52 10.0 1.8 2.7 7.7 1.0 2.3 1 1 1 2 2 2 0 Influenza C hemagglutinin stalk DUF3800 PF12686.7 PRP82643.1 - 4.4 8.0 9.5 3.2e+02 2.0 7.7 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) L31 PF09784.9 PRP82643.1 - 8.2 6.9 10.0 3.1 8.3 5.8 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Syntaxin_2 PF14523.6 PRP82644.1 - 5.5e-21 74.8 10.6 3.5e-20 72.3 3.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 PRP82644.1 - 2.4e-11 43.4 4.1 2.6e-11 43.3 0.4 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 PRP82644.1 - 2.5e-06 27.3 8.5 0.0014 18.3 0.7 2.4 2 0 0 2 2 2 2 Syntaxin Prominin PF05478.11 PRP82644.1 - 0.00031 18.8 4.2 0.0016 16.5 0.3 2.1 2 0 0 2 2 2 1 Prominin Synaptobrevin PF00957.21 PRP82644.1 - 0.0017 18.1 0.6 0.0017 18.1 0.6 2.6 2 1 0 2 2 2 1 Synaptobrevin DASH_Dam1 PF08653.10 PRP82644.1 - 0.0027 17.5 0.5 0.45 10.3 0.0 3.4 3 0 0 3 3 3 1 DASH complex subunit Dam1 DASH_Duo1 PF08651.10 PRP82644.1 - 0.0073 16.1 5.1 6.2 6.7 0.2 3.5 3 0 0 3 3 3 1 DASH complex subunit Duo1 Tex_N PF09371.10 PRP82644.1 - 0.0075 16.0 0.3 3.4 7.3 0.1 2.3 2 0 0 2 2 2 2 Tex-like protein N-terminal domain PCRF PF03462.18 PRP82644.1 - 0.051 13.4 4.0 1.7 8.5 0.2 2.4 2 1 0 2 2 2 0 PCRF domain DUF4366 PF14283.6 PRP82644.1 - 0.052 13.6 0.0 0.087 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MCPsignal PF00015.21 PRP82644.1 - 0.069 13.0 8.6 0.067 13.0 1.1 3.0 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Orf78 PF06024.12 PRP82644.1 - 0.13 12.6 0.8 0.24 11.7 0.0 1.9 2 0 0 2 2 1 0 Orf78 (ac78) DUF2207 PF09972.9 PRP82644.1 - 0.28 9.9 2.2 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMPIT PF07851.13 PRP82644.1 - 0.29 10.3 4.4 1.4 8.1 1.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein Atg14 PF10186.9 PRP82644.1 - 0.31 10.1 4.9 4.7 6.2 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HisKA PF00512.25 PRP82644.1 - 0.36 10.9 2.2 7.1 6.7 0.1 2.8 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain YtxH PF12732.7 PRP82644.1 - 0.47 11.0 4.7 1.8 9.2 0.6 3.0 3 1 0 3 3 3 0 YtxH-like protein NPV_P10 PF05531.12 PRP82644.1 - 0.54 10.8 7.5 1.4 9.5 0.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 PRP82644.1 - 0.58 10.2 11.3 1.2 9.2 0.8 3.1 2 1 0 3 3 3 0 Laminin Domain II ISG65-75 PF11727.8 PRP82644.1 - 0.6 9.3 4.1 4.8 6.3 0.2 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein 4HB_MCP_1 PF12729.7 PRP82644.1 - 1 8.9 16.1 0.073 12.6 3.1 2.9 3 1 0 3 3 3 0 Four helix bundle sensory module for signal transduction Tup_N PF08581.10 PRP82644.1 - 1.2 9.5 5.1 3.3 8.1 0.6 2.7 2 1 0 2 2 2 0 Tup N-terminal zf-C4H2 PF10146.9 PRP82644.1 - 1.2 9.4 7.9 0.29 11.4 2.5 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein DUF948 PF06103.11 PRP82644.1 - 1.4 9.2 8.9 6.6 7.1 1.1 3.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 PRP82644.1 - 4.3 7.9 9.5 0.56 10.7 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 Voltage_CLC PF00654.20 PRP82645.1 - 7.9e-78 262.2 20.5 7.9e-78 262.2 20.5 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PRP82645.1 - 5.1e-18 65.3 0.0 2.4e-10 40.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain PspC PF04024.12 PRP82645.1 - 0.22 11.4 1.7 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 PspC domain DnaJ-X PF14308.6 PRP82646.1 - 3.2e-30 105.2 0.0 5.9e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 PRP82646.1 - 2.1e-26 91.8 0.4 4.6e-26 90.7 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain TIP49_C PF17856.1 PRP82646.1 - 0.062 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 TIP49 AAA-lid domain DUF4108 PF13390.6 PRP82647.1 - 1.8e-05 24.7 2.5 0.76 9.7 0.0 4.8 4 1 0 4 4 4 1 Protein of unknown function (DUF4108) Sulf_transp PF04143.14 PRP82647.1 - 0.0028 17.3 4.0 0.1 12.1 0.3 3.3 2 1 1 3 3 3 1 Sulphur transport Mak10 PF04112.13 PRP82647.1 - 0.02 14.4 3.6 3.3 7.2 0.2 3.4 3 0 0 3 3 3 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF2573 PF10835.8 PRP82647.1 - 0.08 13.3 4.8 1.2e+02 3.1 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF2573) Annexin_like PF18411.1 PRP82647.1 - 0.18 12.1 1.6 50 4.3 0.0 4.0 4 0 0 4 4 4 0 Annexin-like domain SWC7 PF17330.2 PRP82647.1 - 0.22 11.6 4.5 1 9.5 0.1 4.0 6 0 0 6 6 6 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Phenol_MetA_deg PF13557.6 PRP82647.1 - 0.74 9.7 4.4 38 4.1 0.1 3.7 4 0 0 4 4 4 0 Putative MetA-pathway of phenol degradation Ac76 PF05814.11 PRP82647.1 - 1.3 9.0 7.4 16 5.6 0.0 4.8 5 1 1 6 6 6 0 Orf76 (Ac76) Peptidase_S74 PF13884.6 PRP82647.1 - 8.7 6.7 12.0 1.3e+02 3.0 0.0 4.9 6 0 0 6 6 6 0 Chaperone of endosialidase LRR_6 PF13516.6 PRP82649.1 - 3e-12 45.5 11.8 0.00036 20.4 0.1 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 PRP82649.1 - 1.6e-06 27.8 2.5 8.7 7.3 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich Repeat Carm_PH PF17888.1 PRP82649.1 - 0.031 14.6 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 Carmil pleckstrin homology domain LRR_4 PF12799.7 PRP82649.1 - 0.051 14.0 14.5 17 6.0 0.0 6.8 6 2 3 9 9 9 0 Leucine Rich repeats (2 copies) GST_N PF02798.20 PRP82650.1 - 3.1e-15 56.3 0.0 7e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP82650.1 - 1.1e-11 45.0 0.0 2.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP82650.1 - 2.8e-10 40.3 0.1 6.5e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PRP82650.1 - 2.2e-09 37.5 0.0 4.5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP82650.1 - 7.3e-09 35.7 0.1 2.3e-08 34.1 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP82650.1 - 2.2e-08 34.0 0.2 4.3e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase_Tyr PF07714.17 PRP82652.1 - 4.1e-35 121.3 0.3 6.3e-35 120.7 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82652.1 - 1.6e-22 80.2 0.3 2.6e-22 79.5 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP82652.1 - 9e-13 47.8 24.2 0.00032 20.4 2.3 5.1 4 1 1 5 5 5 5 Leucine rich repeat GPS PF01825.21 PRP82652.1 - 2.4e-10 40.8 3.2 7e-10 39.3 3.2 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP82652.1 - 2e-09 37.5 23.7 0.37 11.3 2.8 7.1 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP82652.1 - 0.0054 16.7 3.9 8.2 6.8 0.4 5.5 5 0 0 5 5 5 1 Leucine Rich repeat SCAB_CC PF16712.5 PRP82652.1 - 0.015 15.1 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein LRR_1 PF00560.33 PRP82652.1 - 0.029 14.9 17.8 18 6.4 1.1 8.8 8 1 0 9 9 9 0 Leucine Rich Repeat DUF3395 PF11875.8 PRP82653.1 - 1.4e-38 132.2 0.1 4.2e-38 130.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 PRP82653.1 - 8.7e-19 67.4 0.3 2.8e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Alpha_L_fucos PF01120.17 PRP82653.1 - 0.023 14.2 0.3 0.036 13.5 0.3 1.2 1 0 0 1 1 1 0 Alpha-L-fucosidase Recep_L_domain PF01030.24 PRP82654.1 - 0.22 11.6 8.0 5.8 7.1 1.8 3.9 3 1 1 4 4 4 0 Receptor L domain Cullin PF00888.22 PRP82656.1 - 2.6e-120 402.9 16.5 4.4e-120 402.2 16.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PRP82656.1 - 8.9e-18 64.1 2.9 8.9e-18 64.1 2.9 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain TPR_8 PF13181.6 PRP82656.1 - 0.11 12.7 0.6 3.7 8.0 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Bacteriocin_IId PF09221.10 PRP82656.1 - 0.18 12.0 1.0 0.36 11.0 1.0 1.4 1 0 0 1 1 1 0 Bacteriocin class IId cyclical uberolysin-like PH PF00169.29 PRP82657.1 - 9.7e-07 29.3 1.8 2e-06 28.3 1.8 1.6 1 0 0 1 1 1 1 PH domain IQ_SEC7_PH PF16453.5 PRP82657.1 - 0.0029 17.6 0.0 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 PH domain TFIIA PF03153.13 PRP82657.1 - 0.032 14.2 28.9 0.047 13.7 28.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 PRP82657.1 - 7.2 4.4 19.8 9.6 4.0 19.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Put_Phosphatase PF06888.12 PRP82658.1 - 1.7e-44 152.0 0.2 2e-44 151.8 0.2 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 PRP82658.1 - 7.3e-07 29.8 0.0 1.6e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PRP82658.1 - 0.0021 18.2 0.0 0.035 14.2 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Guanylate_cyc PF00211.20 PRP82659.1 - 4.2e-31 108.0 0.1 6.9e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 PRP82660.1 - 3.2e-95 317.0 3.4 1.9e-30 105.8 0.1 3.3 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain RTP1_C1 PF10363.9 PRP82660.1 - 9.8e-06 25.7 2.6 3.6 7.8 0.0 4.4 4 0 0 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 TPR_6 PF13174.6 PRP82660.1 - 0.002 18.6 1.0 1.9 9.3 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat T6SS_VasE PF05936.12 PRP82660.1 - 0.0021 16.8 0.8 1.4 7.5 0.1 2.3 2 0 0 2 2 2 2 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Peptidase_C11 PF03415.14 PRP82660.1 - 0.0029 17.1 1.7 0.38 10.1 0.1 2.5 2 0 0 2 2 2 2 Clostripain family TPR_19 PF14559.6 PRP82660.1 - 0.0047 17.4 0.6 5.2 7.7 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP82660.1 - 0.011 15.8 0.6 0.53 10.4 0.1 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MscS_porin PF12795.7 PRP82660.1 - 0.036 13.6 6.3 0.49 9.9 0.4 2.7 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain DUF2373 PF10180.9 PRP82660.1 - 0.055 13.3 0.2 8.1 6.4 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2373) Zein-binding PF04576.15 PRP82660.1 - 0.072 13.4 4.1 19 5.6 0.1 3.8 3 0 0 3 3 3 0 Zein-binding MEF2_binding PF09047.10 PRP82660.1 - 0.085 12.7 1.2 94 3.0 0.0 3.6 3 0 0 3 3 3 0 MEF2 binding Ribosomal_S6 PF01250.17 PRP82660.1 - 0.092 13.0 0.0 43 4.5 0.0 3.5 3 0 0 3 3 3 0 Ribosomal protein S6 TPR_2 PF07719.17 PRP82660.1 - 0.21 11.8 0.7 32 5.0 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat XOO_2897-deam PF14440.6 PRP82660.1 - 0.66 10.1 3.3 1.1e+02 3.0 0.1 3.5 3 0 0 3 3 3 0 Xanthomonas XOO_2897-like deaminase Lung_7-TM_R PF06814.13 PRP82660.1 - 9 5.4 11.7 0.38 9.9 0.4 3.6 4 0 0 4 4 4 0 Lung seven transmembrane receptor DUF684 PF05075.14 PRP82661.1 - 0.069 12.1 0.1 0.067 12.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF684) Guanylate_cyc PF00211.20 PRP82662.1 - 1.7e-30 106.0 0.1 3.1e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RTP1_C1 PF10363.9 PRP82662.1 - 0.12 12.6 0.1 0.76 10.0 0.0 2.3 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Lung_7-TM_R PF06814.13 PRP82662.1 - 0.13 11.5 2.2 1.2 8.3 0.1 2.9 3 0 0 3 3 3 0 Lung seven transmembrane receptor Guanylate_cyc PF00211.20 PRP82663.1 - 2e-19 69.9 0.0 2.9e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fis1_TPR_C PF14853.6 PRP82663.1 - 0.011 15.8 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 PRP82663.1 - 0.085 13.4 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat rve PF00665.26 PRP82664.1 - 2.2e-16 60.1 0.0 5.2e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 PRP82664.1 - 2.6e-09 36.9 0.1 4.9e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Integrase_Zn PF02022.19 PRP82664.1 - 0.1 12.6 1.7 0.21 11.5 1.7 1.6 1 0 0 1 1 1 0 Integrase Zinc binding domain 7TM-7TMR_HD PF07698.11 PRP82664.1 - 0.15 11.8 0.1 0.15 11.8 0.1 1.6 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Glyco_hydro81C PF17652.1 PRP82665.1 - 1.6e-71 241.4 0.8 3.1e-71 240.4 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 PRP82665.1 - 6.8e-32 110.9 10.7 1.4e-31 109.9 10.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain OTU PF02338.19 PRP82665.1 - 4.1e-16 59.6 0.0 1.5e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Fascin PF06268.13 PRP82665.1 - 2.1e-06 27.9 0.2 2.7 8.3 0.0 4.4 3 1 1 4 4 4 2 Fascin domain Peptidase_C65 PF10275.9 PRP82665.1 - 0.00048 19.7 0.5 0.0039 16.7 0.1 2.4 2 1 1 3 3 3 1 Peptidase C65 Otubain Mid2 PF04478.12 PRP82665.1 - 0.0055 16.6 0.7 0.014 15.2 0.7 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Phage_HK97_TLTM PF06120.11 PRP82665.1 - 0.17 11.1 0.2 0.31 10.2 0.2 1.3 1 0 0 1 1 1 0 Tail length tape measure protein TMEM154 PF15102.6 PRP82665.1 - 0.17 11.8 1.2 0.68 9.8 1.2 2.1 1 0 0 1 1 1 0 TMEM154 protein family Podoplanin PF05808.11 PRP82665.1 - 0.78 9.8 13.9 0.054 13.6 7.8 2.2 2 0 0 2 2 2 0 Podoplanin Pkinase_Tyr PF07714.17 PRP82666.1 - 8.5e-60 202.2 0.2 1.2e-59 201.8 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82666.1 - 1.1e-34 120.0 0.1 1.6e-34 119.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP82666.1 - 1.1e-08 35.4 4.0 1.1e-08 35.4 4.0 2.4 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Kdo PF06293.14 PRP82666.1 - 1.3e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sigma_reg_N PF13800.6 PRP82666.1 - 0.12 12.7 0.1 7.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CholecysA-Rec_N PF09193.10 PRP82666.1 - 4.1 7.5 6.7 46 4.1 0.1 4.2 5 0 0 5 5 5 0 Cholecystokinin A receptor, N-terminal DJ-1_PfpI PF01965.24 PRP82668.1 - 8e-14 51.8 0.0 1.4e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 PRP82668.1 - 3.2e-05 23.7 0.0 0.00027 20.7 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 PRP82668.1 - 0.015 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases PP2C_2 PF13672.6 PRP82669.1 - 0.00027 20.6 0.0 0.0016 18.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP82669.1 - 0.011 15.7 0.4 0.44 10.4 0.1 2.8 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) SpdB PF05122.13 PRP82669.1 - 0.033 14.3 0.6 0.073 13.2 0.6 1.6 1 0 0 1 1 1 0 Mobile element transfer protein TPMT PF05724.11 PRP82670.1 - 4.1e-37 128.0 0.0 4.9e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 PRP82670.1 - 7.4e-09 36.2 0.0 1.3e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP82670.1 - 5.6e-08 33.3 0.0 8.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP82670.1 - 1.1e-06 29.3 0.0 1.5e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP82670.1 - 5.1e-06 26.4 0.0 6.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Gelsolin PF00626.22 PRP82671.1 - 1e-26 92.6 0.4 3.1e-08 33.4 0.0 4.5 4 0 0 4 4 4 4 Gelsolin repeat VHP PF02209.19 PRP82671.1 - 6.2e-13 48.6 0.3 2.1e-12 46.9 0.3 2.0 1 0 0 1 1 1 1 Villin headpiece domain RyR PF02026.16 PRP82671.1 - 0.018 15.2 0.3 0.056 13.6 0.3 1.8 1 0 0 1 1 1 0 RyR domain TatD_DNase PF01026.21 PRP82672.1 - 4.3e-36 124.6 0.0 8e-36 123.7 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase ThuA PF06283.11 PRP82672.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Trehalose utilisation MAM1 PF10434.9 PRP82674.1 - 0.075 12.6 10.8 0.043 13.4 8.7 1.6 1 1 1 2 2 2 0 Monopolin complex protein MAM1 FTO_NTD PF12933.7 PRP82674.1 - 0.12 11.6 3.6 0.19 11.0 3.6 1.3 1 0 0 1 1 1 0 FTO catalytic domain ALMT PF11744.8 PRP82674.1 - 4 6.2 5.9 5.7 5.7 5.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 PRP82674.1 - 7.7 5.2 8.9 10 4.8 8.9 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 PRP82675.1 - 0.00092 18.0 23.1 0.00092 18.0 23.1 3.4 3 1 0 3 3 3 1 Nucleoporin protein Ndc1-Nup FG-GAP PF01839.23 PRP82676.1 - 1.5e-28 98.5 27.4 1.6e-06 28.1 0.1 5.8 5 0 0 5 5 5 5 FG-GAP repeat VCBS PF13517.6 PRP82676.1 - 1.7e-17 63.7 18.8 3.2e-07 30.9 1.8 4.5 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Zn_dep_PLPC PF00882.18 PRP82676.1 - 2.3e-14 53.8 0.5 4.4e-14 52.9 0.5 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C DUF1356 PF07092.12 PRP82676.1 - 7.3e-08 32.0 1.4 1.2e-07 31.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) TcdB_toxin_midN PF12256.8 PRP82676.1 - 5.9e-06 25.8 1.8 0.025 14.0 0.0 4.8 5 0 0 5 5 5 1 Insecticide toxin TcdB middle/N-terminal region LEA_2 PF03168.13 PRP82676.1 - 0.00041 20.8 0.1 0.0011 19.4 0.1 1.8 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1509 PF07420.11 PRP82676.1 - 0.22 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) SLBP_RNA_bind PF15247.6 PRP82677.1 - 9e-25 86.6 0.3 2.1e-24 85.4 0.3 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Tubulin PF00091.25 PRP82678.1 - 1.2e-63 214.9 0.0 1.7e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PRP82678.1 - 8.4e-31 106.8 0.0 1.7e-29 102.6 0.0 2.4 1 1 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PRP82678.1 - 0.00098 18.9 0.0 0.0027 17.4 0.0 1.8 1 1 0 1 1 1 1 Tubulin domain TIG PF01833.24 PRP82680.1 - 2.4e-130 424.9 434.2 2.2e-10 40.5 8.1 32.2 28 4 5 33 33 33 28 IPT/TIG domain Pkinase_Tyr PF07714.17 PRP82680.1 - 5.6e-65 219.2 0.0 7.7e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82680.1 - 4.5e-44 150.8 0.0 7.5e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP82680.1 - 6.5e-09 35.4 7.7 6.2e-05 22.7 0.4 3.2 1 1 1 2 2 2 2 Leucine rich repeat PAN_4 PF14295.6 PRP82680.1 - 1.2e-05 25.2 0.9 3.4e-05 23.7 0.9 1.9 1 0 0 1 1 1 1 PAN domain Adeno_E1B_55K PF01696.17 PRP82680.1 - 0.0003 19.6 2.5 0.00091 18.0 1.1 2.3 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen Kdo PF06293.14 PRP82680.1 - 0.00042 19.7 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP82680.1 - 0.0038 16.1 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase MobC PF05713.11 PRP82680.1 - 0.11 13.0 0.5 0.28 11.7 0.5 1.6 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) LRR_11 PF18831.1 PRP82680.1 - 0.2 11.2 6.6 0.092 12.3 1.1 3.5 2 0 0 2 2 2 0 Leucine-rich repeat PAN_2 PF08276.11 PRP82680.1 - 0.27 11.4 1.2 0.88 9.7 1.2 1.8 1 0 0 1 1 1 0 PAN-like domain LRR_4 PF12799.7 PRP82680.1 - 6.2 7.4 22.4 0.34 11.4 2.3 4.9 1 1 4 5 5 5 0 Leucine Rich repeats (2 copies) HA PF03457.14 PRP82681.1 - 0.00087 19.6 0.5 0.00087 19.6 0.5 1.9 2 0 0 2 2 2 1 Helicase associated domain YabA PF06156.13 PRP82681.1 - 0.049 14.3 1.0 0.049 14.3 1.0 3.4 4 0 0 4 4 4 0 Initiation control protein YabA bZIP_2 PF07716.15 PRP82681.1 - 5.6 7.1 12.1 2.1 8.5 7.0 2.6 2 0 0 2 2 2 0 Basic region leucine zipper GIDE PF12483.8 PRP82684.1 - 3.3e-13 49.3 0.0 5.2e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 E3 Ubiquitin ligase SH3_2 PF07653.17 PRP82685.1 - 2.8e-12 46.1 0.0 7.6e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PRP82685.1 - 2.1e-11 43.5 0.1 4.2e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP82685.1 - 1.3e-10 40.7 0.1 2.2e-10 40.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Peroxin-13_N PF04088.13 PRP82685.1 - 0.00077 19.8 0.4 0.0013 19.0 0.4 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region G6PD_bact PF10786.9 PRP82685.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DUF4874 PF16173.5 PRP82686.1 - 2.9e-10 40.0 0.0 9.5e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4874) DUF4832 PF16116.5 PRP82686.1 - 0.0015 18.4 0.3 0.0031 17.4 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4832) VIT_2 PF13757.6 PRP82686.1 - 0.21 11.5 1.0 2.2 8.2 0.5 2.3 2 0 0 2 2 2 0 Vault protein inter-alpha-trypsin domain PAS_8 PF13188.7 PRP82687.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 PAS domain MFS_1 PF07690.16 PRP82688.1 - 4.1e-50 170.7 37.7 7.2e-45 153.4 26.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily LRR_4 PF12799.7 PRP82689.1 - 4e-20 71.6 26.1 5e-05 23.6 0.4 5.5 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP82689.1 - 1.6e-14 53.4 17.9 8e-05 22.3 0.1 4.5 4 0 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 PRP82689.1 - 7.7e-14 51.6 9.8 1.3e-12 47.5 2.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 PRP82689.1 - 3e-06 26.8 6.6 4.6 7.6 0.0 7.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 PRP82689.1 - 0.11 13.1 17.9 17 6.5 1.7 7.1 7 2 0 7 7 7 0 Leucine Rich Repeat BUD22 PF09073.10 PRP82689.1 - 2.4 7.4 22.8 0.1 11.9 15.1 2.0 2 0 0 2 2 2 0 BUD22 ubiquitin PF00240.23 PRP82690.1 - 1.2e-68 226.8 7.5 8.4e-34 115.2 0.9 2.4 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 PRP82690.1 - 5.2e-32 109.5 8.0 1.7e-15 56.6 1.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP82690.1 - 5.5e-12 46.0 3.2 0.00013 22.3 0.2 3.5 2 2 0 2 2 2 2 Ubiquitin-like domain zf-AN1 PF01428.16 PRP82690.1 - 8.6e-12 45.0 5.8 1.6e-11 44.2 5.8 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD_2 PF13881.6 PRP82690.1 - 1.6e-08 34.6 1.1 0.0022 18.1 0.0 3.1 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 PRP82690.1 - 7.9e-08 32.1 0.8 0.015 15.2 0.1 2.4 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 PRP82690.1 - 1.7e-07 31.8 2.0 0.024 15.2 0.1 3.1 1 1 1 3 3 3 2 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP82690.1 - 1.8e-07 31.4 2.7 0.011 16.1 0.5 2.5 2 1 0 2 2 2 2 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 PRP82690.1 - 0.00021 21.1 0.0 0.76 9.6 0.0 2.3 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 PRP82690.1 - 0.0017 18.4 11.5 9.5 6.3 0.2 4.7 5 0 0 5 5 5 0 Ubiquitin-like domain DUF3861 PF12977.7 PRP82690.1 - 0.0072 16.5 0.4 6.2 7.1 0.0 2.5 2 0 0 2 2 2 2 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 PRP82690.1 - 0.018 15.4 0.0 6.6 7.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 PRP82690.1 - 0.024 14.5 0.7 6.8 6.6 0.1 2.6 2 0 0 2 2 2 0 ACT domain Big_3_3 PF13750.6 PRP82690.1 - 0.062 13.0 0.0 11 5.7 0.0 2.6 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) UDP-g_GGTase PF06427.11 PRP82690.1 - 0.071 13.2 3.2 6.2 7.0 0.1 2.5 3 0 0 3 3 2 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF1940 PF09155.10 PRP82690.1 - 0.074 13.2 0.5 16 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) AUDH_Cupin PF18637.1 PRP82690.1 - 0.087 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain TmoB PF06234.12 PRP82690.1 - 0.13 12.3 0.1 29 4.8 0.0 2.7 2 1 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) PI3K_p85B PF02192.16 PRP82690.1 - 0.67 9.7 2.9 34 4.3 0.1 2.9 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Tash_PEST PF07708.11 PRP82690.1 - 0.76 10.0 9.6 5.7 7.2 1.4 2.4 2 0 0 2 2 2 0 Tash protein PEST motif BET PF17035.5 PRP82692.1 - 1.9e-24 85.6 1.1 5.6e-24 84.1 1.1 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 PRP82692.1 - 1.2e-16 60.6 0.0 2.5e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Bromodomain DUSP PF06337.12 PRP82692.1 - 0.027 15.1 3.0 0.07 13.8 0.1 2.7 2 0 0 2 2 2 0 DUSP domain Macoilin PF09726.9 PRP82692.1 - 0.29 9.6 52.5 0.0042 15.7 27.0 2.2 2 0 0 2 2 2 0 Macoilin family FlaC_arch PF05377.11 PRP82692.1 - 1 9.8 10.9 0.67 10.4 1.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DASH_Hsk3 PF08227.11 PRP82692.1 - 4.3 7.8 9.0 0.21 11.9 3.0 1.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Phytochelatin PF05023.14 PRP82693.1 - 2.4e-75 252.4 0.0 5e-75 251.4 0.0 1.6 1 0 0 1 1 1 1 Phytochelatin synthase LRR_6 PF13516.6 PRP82693.1 - 4.4e-31 104.3 35.2 0.0014 18.5 0.1 13.4 13 1 0 13 13 13 10 Leucine Rich repeat LRR_4 PF12799.7 PRP82693.1 - 5.7e-10 39.3 13.2 0.083 13.4 0.0 6.6 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP82693.1 - 7.7e-08 32.0 21.7 0.0017 18.1 1.4 6.6 4 3 3 7 7 7 5 Leucine rich repeat SAP PF02037.27 PRP82693.1 - 5.9e-07 29.1 1.4 1e-06 28.4 0.1 2.2 2 0 0 2 2 2 1 SAP domain LRR_1 PF00560.33 PRP82693.1 - 1.4e-05 24.9 2.4 91 4.2 0.0 8.8 10 0 0 10 10 10 0 Leucine Rich Repeat Phytochelatin_C PF09328.10 PRP82693.1 - 0.00012 21.5 1.7 0.37 10.1 0.0 3.0 2 1 0 3 3 3 2 Domain of unknown function (DUF1984) Peptidase_C39_2 PF13529.6 PRP82693.1 - 0.00075 20.1 0.1 0.0053 17.3 0.1 2.4 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 PRP82693.1 - 0.0013 18.6 0.1 0.021 14.7 0.0 3.1 2 1 0 2 2 2 1 Peptidase C39 family Beta_helix PF13229.6 PRP82693.1 - 0.57 10.0 2.3 0.64 9.9 0.1 2.1 1 1 1 2 2 2 0 Right handed beta helix region BBE PF08031.12 PRP82694.1 - 2.2e-11 43.6 0.0 5.7e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3909 PF13077.6 PRP82694.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3909) DUF1580 PF07618.11 PRP82694.1 - 0.38 10.4 4.2 1.8 8.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Fic PF02661.18 PRP82695.1 - 1.8e-11 44.8 0.0 8e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 Fic/DOC family rve PF00665.26 PRP82696.1 - 5.3e-16 58.9 0.0 1.1e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 PRP82696.1 - 5.4e-13 48.6 0.4 1e-12 47.7 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.27 PRP82697.1 - 6.2e-13 48.8 0.0 1.3e-12 47.7 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 PRP82697.1 - 0.014 16.0 1.7 0.02 15.6 0.3 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DNase_II PF03265.15 PRP82698.1 - 1.5e-07 31.0 0.2 2.2e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 Deoxyribonuclease II BPL_N PF09825.9 PRP82701.1 - 0.029 13.4 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal F-box-like PF12937.7 PRP82702.1 - 0.025 14.5 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 F-box-like DUF3348 PF11828.8 PRP82702.1 - 0.048 13.3 0.6 0.071 12.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) End3 PF12761.7 PRP82703.1 - 0.062 13.5 0.2 0.079 13.1 0.2 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Ank_2 PF12796.7 PRP82704.1 - 3.5e-06 27.5 0.0 4.5e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box_4 PF15966.5 PRP82704.1 - 3.3e-05 23.8 0.0 7.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 F-box Ank_3 PF13606.6 PRP82704.1 - 0.00036 20.8 0.0 0.036 14.6 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 PRP82704.1 - 0.0014 19.2 0.0 0.64 10.7 0.0 3.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP82704.1 - 0.025 15.0 0.0 0.068 13.7 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat DNA_pol_B PF00136.21 PRP82707.1 - 0.041 12.6 0.1 0.071 11.8 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase family B PEPCK_GTP PF00821.18 PRP82708.1 - 1.5e-171 570.1 1.1 2.5e-171 569.4 0.1 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 PRP82708.1 - 3.8e-97 324.2 0.0 6.8e-97 323.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain SNF2_N PF00176.23 PRP82708.1 - 3.1e-47 161.0 0.0 9.4e-47 159.4 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain PseudoU_synth_1 PF01416.20 PRP82708.1 - 6.3e-34 116.7 0.0 3.2e-32 111.2 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase Helicase_C PF00271.31 PRP82708.1 - 1.6e-13 51.0 0.1 4.9e-13 49.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.11 PRP82709.1 - 6.9e-15 55.8 0.3 6.9e-15 55.8 0.3 1.7 2 0 0 2 2 2 1 DNA replication factor CDT1 like PI3_PI4_kinase PF00454.27 PRP82710.1 - 5.1e-46 157.5 0.0 5.1e-46 157.5 0.0 3.1 2 2 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PRP82710.1 - 1.9e-41 141.5 0.1 4.4e-41 140.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 PRP82710.1 - 2.3e-11 43.8 0.0 2.3e-11 43.8 0.0 2.6 2 1 0 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 PRP82710.1 - 0.00012 22.2 0.0 0.00034 20.7 0.0 1.8 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain tRNA-synt_2 PF00152.20 PRP82711.1 - 6.2e-78 262.0 0.5 6.2e-78 262.0 0.5 2.4 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) CH PF00307.31 PRP82711.1 - 1.2e-32 112.3 0.0 7.1e-15 55.1 0.0 3.2 2 0 0 2 2 2 2 Calponin homology (CH) domain C2 PF00168.30 PRP82711.1 - 2.3e-17 63.1 0.1 7e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 C2 domain tRNA_anti-codon PF01336.25 PRP82711.1 - 0.0003 20.7 0.0 0.00089 19.2 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PRP82711.1 - 0.0097 15.4 0.2 0.043 13.3 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) HsbA PF12296.8 PRP82711.1 - 2.5 8.5 12.0 11 6.5 0.2 5.1 5 1 0 5 5 5 0 Hydrophobic surface binding protein A UCH PF00443.29 PRP82712.1 - 2e-45 155.3 0.1 2.9e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP82712.1 - 1.5e-08 34.7 3.6 1.5e-07 31.3 3.6 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 PRP82712.1 - 7.8e-08 32.0 0.1 5e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family XRCC4 PF06632.12 PRP82712.1 - 0.01 14.7 0.6 0.018 13.9 0.6 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Peptidase_C98 PF15499.6 PRP82712.1 - 0.02 14.4 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PS_Dcarbxylase PF02666.15 PRP82713.1 - 3.4e-36 124.7 0.0 6.1e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 PRP82713.1 - 4.4e-33 114.2 0.0 8.7e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 Phophatidylserine decarboxylase AMP-binding PF00501.28 PRP82714.1 - 4.5e-81 272.6 0.0 5.3e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP82714.1 - 7.4e-15 55.7 0.0 1.6e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YjbR PF04237.13 PRP82714.1 - 0.046 14.3 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 YjbR DUF3425 PF11905.8 PRP82715.1 - 4.7e-22 78.3 0.2 1.1e-21 77.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 PRP82715.1 - 1.1e-05 25.4 6.4 1.1e-05 25.4 6.4 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PRP82715.1 - 3.1e-05 24.0 7.3 3.1e-05 24.0 7.3 2.6 3 0 0 3 3 3 1 Basic region leucine zipper XhlA PF10779.9 PRP82715.1 - 6.2 7.1 5.0 1.9 8.7 0.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DHHA1 PF02272.19 PRP82716.1 - 4.7e-08 33.6 0.0 8.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 DHHA1 domain DHH PF01368.20 PRP82716.1 - 0.11 12.7 0.1 0.41 10.9 0.0 2.0 2 1 0 2 2 2 0 DHH family LRR_8 PF13855.6 PRP82717.1 - 6.7e-91 298.0 172.1 1.5e-09 37.5 5.1 20.6 6 4 13 23 23 23 21 Leucine rich repeat LRR_4 PF12799.7 PRP82717.1 - 1.3e-58 193.9 191.7 0.00023 21.5 1.0 24.9 7 5 16 29 29 29 29 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP82717.1 - 8.4e-14 50.0 164.5 0.47 11.2 0.3 37.9 35 5 2 37 37 37 12 Leucine Rich Repeat VIT PF08487.10 PRP82718.1 - 6.3e-32 110.1 0.2 1.7e-30 105.5 0.1 2.9 3 0 0 3 3 3 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PRP82718.1 - 4.7e-25 88.3 0.0 1e-24 87.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP82718.1 - 1.8e-12 47.8 0.0 3.7e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 PRP82718.1 - 1.6e-09 37.5 0.0 5.2e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 PRP82718.1 - 5.5e-09 36.6 0.0 2.6e-08 34.4 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain CobT_C PF11775.8 PRP82718.1 - 0.022 14.4 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain VWA_CoxE PF05762.14 PRP82718.1 - 0.063 12.7 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein WD40 PF00400.32 PRP82719.1 - 2.5e-27 94.6 16.1 0.00015 22.5 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82719.1 - 2.8e-10 40.3 4.1 0.0023 18.2 0.0 4.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP82719.1 - 0.00033 19.7 1.2 1.9 7.3 0.1 3.9 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Ntox21 PF15526.6 PRP82719.1 - 0.61 10.4 2.8 1.1 9.5 0.2 2.5 3 0 0 3 3 3 0 Novel toxin 21 Cnd1 PF12717.7 PRP82720.1 - 4.3e-47 160.1 17.0 1.6e-46 158.3 0.2 5.1 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 PRP82720.1 - 1.7e-25 89.8 7.1 1.8e-25 89.7 0.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd3 PF12719.7 PRP82720.1 - 9e-07 28.4 1.7 4.4e-06 26.1 1.7 2.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 PRP82720.1 - 1.3e-06 28.7 0.4 0.004 17.5 0.0 4.8 4 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 PRP82720.1 - 0.00046 20.2 0.1 17 6.0 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat RTP1_C1 PF10363.9 PRP82720.1 - 0.0019 18.3 1.8 0.2 11.9 0.2 3.6 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Tn7_Tnp_TnsA_C PF08721.11 PRP82720.1 - 0.94 10.2 3.5 6.1 7.5 0.1 4.1 5 0 0 5 5 5 0 TnsA endonuclease C terminal WD40 PF00400.32 PRP82721.1 - 7.1e-26 90.0 35.6 2.6e-05 24.9 0.9 10.1 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82721.1 - 2.2e-16 59.9 9.9 0.0026 18.0 0.0 7.3 3 3 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP82721.1 - 4.9e-07 29.8 2.2 1 9.2 0.0 4.8 2 2 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PRP82721.1 - 0.0033 16.1 9.8 0.73 8.4 0.0 5.3 4 2 1 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 PRP82721.1 - 0.0092 16.0 0.0 0.48 10.5 0.0 3.5 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region DUF3480 PF11979.8 PRP82721.1 - 0.048 12.6 0.1 0.088 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) PALB2_WD40 PF16756.5 PRP82721.1 - 0.054 12.4 2.5 0.39 9.6 0.2 2.8 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain LisH_2 PF16045.5 PRP82722.1 - 5e-07 28.6 0.1 8.7e-07 27.9 0.1 1.4 1 0 0 1 1 1 1 LisH JmjC PF02373.22 PRP82723.1 - 3.5e-12 46.8 0.0 3.5e-12 46.8 0.0 2.4 2 1 0 2 2 1 1 JmjC domain, hydroxylase adh_short PF00106.25 PRP82723.1 - 6.7e-11 42.0 0.1 6.4e-10 38.8 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP82723.1 - 3.5e-06 27.0 0.1 1.8e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PRP82723.1 - 0.0027 16.9 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RP-C_C PF11800.8 PRP82723.1 - 0.028 14.5 4.0 0.054 13.6 4.0 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Agouti PF05039.12 PRP82723.1 - 0.054 14.2 11.3 0.18 12.5 11.3 1.9 1 0 0 1 1 1 0 Agouti protein CAF1 PF04857.20 PRP82723.1 - 0.077 12.1 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 CAF1 family ribonuclease AP3D1 PF06375.11 PRP82723.1 - 0.093 13.0 11.0 0.18 12.0 11.0 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF1682 PF07946.14 PRP82723.1 - 0.13 11.4 16.0 0.6 9.3 15.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) zinc-ribbons_6 PF07191.12 PRP82723.1 - 0.18 11.8 4.9 0.42 10.6 4.9 1.6 1 0 0 1 1 1 0 zinc-ribbons C1_2 PF03107.16 PRP82723.1 - 0.3 11.4 7.9 0.91 9.9 7.9 1.8 1 0 0 1 1 1 0 C1 domain NapB PF03892.14 PRP82723.1 - 0.41 10.7 3.4 15 5.6 1.7 2.5 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) Presenilin PF01080.17 PRP82723.1 - 0.79 8.4 4.0 1.2 7.8 4.0 1.2 1 0 0 1 1 1 0 Presenilin Cytomega_UL84 PF06284.11 PRP82723.1 - 1.2 7.5 4.2 1.8 6.9 4.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein zf-C5HC2 PF02928.16 PRP82723.1 - 1.5 9.3 6.2 3.1 8.3 4.6 2.3 2 0 0 2 2 2 0 C5HC2 zinc finger Connexin PF00029.19 PRP82723.1 - 1.7 8.4 4.2 3 7.5 4.2 1.3 1 0 0 1 1 1 0 Connexin NARP1 PF12569.8 PRP82723.1 - 2.1 7.2 10.7 3.2 6.5 10.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mpp10 PF04006.12 PRP82723.1 - 3.3 6.0 18.2 4.7 5.5 18.2 1.1 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 PRP82723.1 - 5 6.9 11.3 8.2 6.2 11.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.9 PRP82723.1 - 5 7.0 15.9 13 5.6 15.9 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Tau95_N PF17682.1 PRP82724.1 - 2.4e-30 105.3 0.0 2.4e-30 105.3 0.0 2.9 2 1 0 2 2 2 1 Tau95 Triple barrel domain Tau95 PF09734.9 PRP82724.1 - 8.9e-29 101.1 0.7 8.6e-27 94.7 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain TFIIF_beta PF02270.15 PRP82724.1 - 0.0032 17.6 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain CobT PF06213.12 PRP82724.1 - 0.14 11.5 16.6 0.27 10.6 16.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 PRP82724.1 - 5.5 6.2 9.6 11 5.3 9.6 1.5 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 PRP82724.1 - 5.6 6.7 18.2 0.98 9.2 13.6 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4407 PF14362.6 PRP82724.1 - 6 6.1 5.4 8.9 5.6 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 PRP82724.1 - 8.8 6.1 13.7 17 5.2 13.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ipi1_N PF12333.8 PRP82725.1 - 7.1e-14 52.2 0.2 7.1e-14 52.2 0.2 3.8 4 0 0 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation a_DG1_N2 PF18424.1 PRP82725.1 - 0.016 15.3 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 Alpha-Dystroglycan N-terminal domain 2 MBOAT_2 PF13813.6 PRP82725.1 - 0.32 11.3 1.3 0.63 10.4 0.1 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family DUF262 PF03235.14 PRP82725.1 - 2.2 8.4 5.4 3 8.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF262 SGTA_dimer PF16546.5 PRP82726.1 - 0.12 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Homodimerisation domain of SGTA LRR_8 PF13855.6 PRP82728.1 - 8e-56 185.7 71.6 5.6e-08 32.4 6.0 11.3 5 3 6 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 PRP82728.1 - 4.3e-30 103.3 89.7 3.8e-05 24.0 1.5 15.3 5 3 9 17 17 17 15 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP82728.1 - 4.8e-18 65.4 0.9 1.2e-16 60.8 0.9 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_1 PF00560.33 PRP82728.1 - 4.1e-10 38.8 77.5 2.5 9.0 0.4 21.9 22 2 0 22 22 22 2 Leucine Rich Repeat Pkinase PF00069.25 PRP82728.1 - 3.2e-09 36.5 0.6 1.1e-07 31.5 0.6 2.5 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP82728.1 - 9e-09 35.7 0.0 2.3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif SCAB_CC PF16712.5 PRP82728.1 - 0.013 15.4 0.3 0.022 14.6 0.3 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein MitoNEET_N PF10660.9 PRP82728.1 - 0.11 12.5 0.5 7.7 6.6 0.0 4.6 4 0 0 4 4 4 0 Iron-containing outer mitochondrial membrane protein N-terminus RT_RNaseH PF17917.1 PRP82731.1 - 1.2e-67 224.8 0.1 8.9e-36 122.4 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP82731.1 - 1.7e-48 162.8 0.0 1.1e-31 108.8 0.0 2.6 2 0 0 2 2 2 2 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP82731.1 - 3.6e-43 145.5 8.1 2.4e-21 75.6 1.1 2.8 2 0 0 2 2 2 2 Integrase zinc binding domain RVT_1 PF00078.27 PRP82731.1 - 4.8e-43 147.3 2.6 2.6e-26 92.5 0.3 2.5 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PRP82731.1 - 4.8e-18 65.5 0.2 9.7e-13 48.4 0.1 3.1 2 0 0 2 2 2 2 Integrase core domain zf-H2C2 PF09337.10 PRP82731.1 - 1.1e-14 54.4 0.9 3.5e-06 27.1 0.1 2.8 2 0 0 2 2 2 2 H2C2 zinc finger Chromo PF00385.24 PRP82731.1 - 4.3e-10 39.4 2.4 5.3e-10 39.1 0.1 2.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1712 PF08217.11 PRP82731.1 - 0.0026 16.4 0.4 1.9 6.9 0.0 2.6 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) Mob1_phocein PF03637.17 PRP82731.1 - 0.0096 16.0 0.7 5.8 6.9 0.1 3.0 2 0 0 2 2 2 2 Mob1/phocein family DUF727 PF05303.12 PRP82731.1 - 0.11 12.6 0.3 61 3.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF727) Asp_protease_2 PF13650.6 PRP82731.1 - 0.2 12.3 0.0 0.47 11.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease SHQ1 PF04925.15 PRP82731.1 - 0.36 10.4 5.0 13 5.3 0.1 3.2 3 0 0 3 3 3 0 SHQ1 protein Peptidase_C92 PF05708.12 PRP82733.1 - 4.1e-08 33.5 0.0 0.001 19.2 0.0 3.0 3 0 0 3 3 3 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family C2 PF00168.30 PRP82733.1 - 0.082 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 C2 domain Pkinase PF00069.25 PRP82734.1 - 1.3e-63 214.9 0.0 1.6e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82734.1 - 4.4e-35 121.2 0.0 5.3e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP82734.1 - 3.6e-05 23.2 0.0 9.1e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP82734.1 - 0.00014 21.2 0.0 0.00024 20.5 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP82734.1 - 0.0011 18.6 0.1 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PRP82734.1 - 0.014 15.0 0.2 1.1 8.9 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2680 PF10925.8 PRP82734.1 - 0.083 12.9 0.4 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) APH PF01636.23 PRP82734.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CG-1 PF03859.16 PRP82735.1 - 0.065 13.0 0.3 0.68 9.7 0.1 2.2 2 0 0 2 2 2 0 CG-1 domain Pkinase PF00069.25 PRP82736.1 - 2.3e-28 99.3 0.0 4e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82736.1 - 8.4e-12 44.9 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Chromo PF00385.24 PRP82736.1 - 6.2e-09 35.6 0.4 1.5e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.26 PRP82736.1 - 2.9e-07 30.7 0.0 6.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain GDA1_CD39 PF01150.17 PRP82737.1 - 1.6e-76 257.7 0.0 2.4e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Podoplanin PF05808.11 PRP82737.1 - 0.001 19.2 7.8 0.0021 18.2 7.8 1.5 1 0 0 1 1 1 1 Podoplanin DUF1180 PF06679.12 PRP82737.1 - 0.0024 18.3 2.5 0.0048 17.3 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) DUF4366 PF14283.6 PRP82737.1 - 0.075 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 PRP82737.1 - 0.16 11.8 0.2 0.29 11.0 0.2 1.3 1 0 0 1 1 1 0 Rifin TMEM154 PF15102.6 PRP82737.1 - 0.38 10.7 14.7 5.8 6.8 14.9 2.3 1 1 0 1 1 1 0 TMEM154 protein family MGC-24 PF05283.11 PRP82737.1 - 0.47 10.9 14.8 2.5 8.6 14.8 2.2 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Gram_pos_anchor PF00746.21 PRP82737.1 - 0.6 10.1 2.7 0.44 10.5 0.6 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Alpha_GJ PF03229.13 PRP82737.1 - 1 9.9 12.7 0.042 14.4 4.3 2.4 1 1 1 2 2 2 0 Alphavirus glycoprotein J Macoilin PF09726.9 PRP82737.1 - 2.1 6.8 10.9 3.1 6.2 10.9 1.2 1 0 0 1 1 1 0 Macoilin family DUF4699 PF15770.5 PRP82737.1 - 3.2 7.5 11.9 5.3 6.7 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Ank_4 PF13637.6 PRP82738.1 - 4.6e-07 30.3 1.4 0.3 11.7 0.0 4.9 4 2 1 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP82738.1 - 0.00038 20.3 1.1 0.00097 19.0 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP82738.1 - 0.00052 19.8 2.3 0.0014 18.4 2.3 1.8 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.7 PRP82738.1 - 0.0011 19.5 0.0 0.075 13.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) F-box_4 PF15966.5 PRP82738.1 - 0.058 13.3 0.6 0.14 12.1 0.6 1.7 1 0 0 1 1 1 0 F-box Ank_5 PF13857.6 PRP82738.1 - 0.089 13.1 0.2 22 5.5 0.0 4.0 4 1 1 5 5 5 0 Ankyrin repeats (many copies) adh_short PF00106.25 PRP82739.1 - 3.8e-32 111.3 0.2 3e-31 108.4 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP82739.1 - 7e-18 65.0 0.1 2.7e-17 63.1 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP82739.1 - 4.4e-10 39.8 0.4 9.2e-10 38.7 0.4 1.5 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 PRP82739.1 - 0.0024 18.1 0.1 0.0051 17.1 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain YjeF_N PF03853.15 PRP82739.1 - 0.0062 16.4 0.2 0.015 15.2 0.1 1.7 2 0 0 2 2 2 1 YjeF-related protein N-terminus Shikimate_DH PF01488.20 PRP82739.1 - 0.012 15.6 0.1 0.072 13.1 0.1 2.2 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Glyco_trans_4_4 PF13579.6 PRP82739.1 - 0.024 15.1 0.1 0.058 13.8 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Epimerase PF01370.21 PRP82739.1 - 0.071 12.6 0.1 0.16 11.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 PRP82739.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Proteasome PF00227.26 PRP82740.1 - 8e-49 165.7 0.6 9.6e-49 165.4 0.6 1.1 1 0 0 1 1 1 1 Proteasome subunit Dynein_light PF01221.18 PRP82741.1 - 2e-42 143.4 1.1 2.4e-42 143.2 1.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Sigma70_r2 PF04542.14 PRP82741.1 - 0.1 12.3 0.4 0.25 11.1 0.1 1.7 2 0 0 2 2 2 0 Sigma-70 region 2 CBFD_NFYB_HMF PF00808.23 PRP82741.1 - 0.11 12.8 1.1 0.17 12.2 1.1 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ectatomin PF06457.11 PRP82741.1 - 0.17 11.8 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Ectatomin COBRA1 PF06209.13 PRP82743.1 - 2.1e-50 172.0 1.8 2.7e-50 171.6 1.8 1.0 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Copine PF07002.16 PRP82743.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Copine Ribosomal_L34e PF01199.18 PRP82744.1 - 3.1e-38 130.0 5.9 4.2e-38 129.5 5.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Cytochrome_C7 PF14522.6 PRP82744.1 - 0.017 15.1 0.2 0.026 14.5 0.2 1.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_NNT PF03264.14 PRP82744.1 - 0.035 13.8 0.7 0.042 13.5 0.2 1.5 1 1 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region Urocanase PF01175.18 PRP82745.1 - 1.9e-87 292.3 0.1 3.7e-87 291.4 0.1 1.5 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 PRP82745.1 - 2e-67 226.4 0.3 1e-65 220.9 1.1 2.7 2 1 0 2 2 2 1 Urocanase C-terminal domain Urocanase_N PF17391.2 PRP82745.1 - 3.5e-56 188.3 1.1 4.7e-55 184.7 0.2 2.6 3 0 0 3 3 3 1 Urocanase N-terminal domain B12D PF06522.11 PRP82745.1 - 0.00075 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit NiFeSe_Hases PF00374.19 PRP82745.1 - 0.011 14.7 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase DUF489 PF04356.12 PRP82745.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF489) VHS PF00790.19 PRP82747.1 - 1.5e-09 37.8 0.2 2.3e-08 34.0 0.2 2.5 1 1 0 1 1 1 1 VHS domain GAT PF03127.14 PRP82747.1 - 0.00021 21.5 0.5 0.00077 19.7 0.5 2.0 1 0 0 1 1 1 1 GAT domain Phage_gp53 PF11246.8 PRP82747.1 - 0.015 15.0 0.4 0.14 11.8 0.2 2.4 2 1 0 2 2 2 0 Base plate wedge protein 53 DUF4600 PF15372.6 PRP82747.1 - 0.2 12.1 0.8 0.34 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Beta_helix PF13229.6 PRP82748.1 - 7.1e-15 55.2 84.9 5.8e-08 32.8 22.9 5.2 1 1 5 6 6 6 5 Right handed beta helix region Ycf9 PF01737.17 PRP82748.1 - 0.11 12.4 2.1 0.13 12.1 0.4 2.1 2 0 0 2 2 2 0 YCF9 Adeno_E1B_55K PF01696.17 PRP82748.1 - 0.25 10.0 14.3 2.4 6.7 4.8 4.0 2 1 1 3 3 3 0 Adenovirus EB1 55K protein / large t-antigen TGBp3 PF02495.17 PRP82748.1 - 7.3 6.3 6.1 8.4 6.1 0.3 3.8 4 0 0 4 4 4 0 Triple gene block 3 FAD_binding_4 PF01565.23 PRP82750.1 - 2.9e-18 66.0 0.6 5.7e-18 65.0 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PRP82750.1 - 6.5e-11 42.2 0.6 2.2e-10 40.5 0.6 1.9 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_2 PF07992.14 PRP82750.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP82750.1 - 0.07 13.7 0.5 0.16 12.6 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cytokin-bind PF09265.10 PRP82750.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding HlyIII PF03006.20 PRP82751.1 - 6.8e-46 156.8 19.1 9e-46 156.4 19.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.25 PRP82752.1 - 1.1e-64 218.4 0.0 1.3e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82752.1 - 1.6e-37 129.3 0.0 2e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP82752.1 - 1.9e-08 33.9 0.3 3.8e-08 32.9 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP82752.1 - 1.4e-07 30.7 0.0 1.9e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 PRP82752.1 - 2.1e-06 27.5 0.1 3.6e-06 26.7 0.1 1.3 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PRP82752.1 - 2.6e-05 24.3 0.0 7.6e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP82752.1 - 3.4e-05 23.3 0.0 4.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 PRP82752.1 - 0.0035 17.0 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PRP82752.1 - 0.025 13.6 0.1 0.034 13.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 PRP82752.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase AA_permease_2 PF13520.6 PRP82753.1 - 5.9e-35 120.9 47.6 4.5e-34 118.0 47.6 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PRP82753.1 - 4.1e-19 68.5 36.6 1.8e-17 63.1 36.6 2.1 1 1 0 1 1 1 1 Amino acid permease DUF1980 PF09323.10 PRP82753.1 - 5.9 6.8 6.1 61 3.5 2.6 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) EamA PF00892.20 PRP82755.1 - 7.8e-33 113.5 42.1 1.6e-17 64.0 18.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family GST_N_4 PF17172.4 PRP82756.1 - 1.6e-16 60.9 0.0 3.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 PRP82756.1 - 5.4e-11 42.9 0.0 8.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 PRP82756.1 - 2.1e-06 27.4 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1266 PF06889.11 PRP82756.1 - 0.086 12.9 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Guanylate_cyc PF00211.20 PRP82758.1 - 4.7e-31 107.8 0.5 1.2e-30 106.5 0.3 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DUF2935 PF11155.8 PRP82758.1 - 0.059 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) FtsL PF04999.13 PRP82758.1 - 0.11 12.5 4.6 0.79 9.8 0.1 2.5 2 0 0 2 2 2 0 Cell division protein FtsL BSD PF03909.17 PRP82759.1 - 4.2e-11 42.7 2.7 1.4e-10 41.0 0.0 3.0 3 0 0 3 3 3 1 BSD domain YqhG PF11079.8 PRP82759.1 - 0.035 13.1 0.4 0.48 9.3 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein YqhG of unknown function Ndc1_Nup PF09531.10 PRP82759.1 - 10 4.7 11.4 0.33 9.6 4.2 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 PRP82760.1 - 0.0035 17.9 0.0 0.0046 17.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP82760.1 - 0.028 14.9 0.0 2.4 9.0 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat AAA_2 PF07724.14 PRP82762.1 - 3.7e-50 170.4 0.0 3.7e-49 167.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PRP82762.1 - 1.2e-34 118.3 1.0 1.2e-34 118.3 1.0 2.2 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 PRP82762.1 - 4e-24 84.5 0.0 1.4e-23 82.8 0.0 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 PRP82762.1 - 2.3e-21 76.6 0.0 1.3e-11 45.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP82762.1 - 1.4e-13 51.0 0.0 5.8e-09 36.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP82762.1 - 5.8e-12 46.3 0.6 4e-05 24.1 0.2 3.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PRP82762.1 - 4.2e-09 36.8 0.5 0.00071 19.9 0.0 3.9 2 2 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 PRP82762.1 - 1.1e-05 24.9 0.3 0.053 12.9 0.2 2.8 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI TniB PF05621.11 PRP82762.1 - 1.2e-05 24.9 0.1 0.024 14.1 0.0 3.7 2 1 0 2 2 2 1 Bacterial TniB protein TsaE PF02367.17 PRP82762.1 - 1.5e-05 25.0 0.1 0.75 9.8 0.0 3.7 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 PRP82762.1 - 7e-05 23.4 1.7 0.0057 17.2 0.0 3.4 3 2 0 3 3 3 1 AAA domain AAA_14 PF13173.6 PRP82762.1 - 9.6e-05 22.4 0.0 0.71 9.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 PRP82762.1 - 0.00011 22.5 0.0 0.14 12.6 0.0 3.2 3 0 0 3 3 3 1 RNA helicase AAA_7 PF12775.7 PRP82762.1 - 0.00016 21.3 0.0 0.52 9.8 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 PRP82762.1 - 0.00026 20.8 0.0 0.065 12.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 PRP82762.1 - 0.00026 20.8 0.0 0.52 10.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 PRP82762.1 - 0.00058 19.6 0.1 0.45 10.3 0.0 3.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 PRP82762.1 - 0.00073 19.5 5.0 1 9.2 0.1 4.0 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea Roc PF08477.13 PRP82762.1 - 0.00077 19.7 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 PRP82762.1 - 0.0016 18.2 0.0 0.77 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PRP82762.1 - 0.0019 17.8 0.0 0.3 10.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 PRP82762.1 - 0.002 18.1 0.0 0.85 9.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 PRP82762.1 - 0.0026 17.7 0.1 2.3 8.1 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 PRP82762.1 - 0.003 17.4 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Torsin PF06309.11 PRP82762.1 - 0.0061 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_33 PF13671.6 PRP82762.1 - 0.01 16.0 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 PRP82762.1 - 0.012 15.6 0.0 0.89 9.5 0.0 3.2 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 PRP82762.1 - 0.023 14.5 0.0 7.9 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 PRP82762.1 - 0.029 14.1 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 PRP82762.1 - 0.029 14.9 0.4 4.7 7.7 0.0 3.2 3 0 0 3 3 3 0 ABC transporter NTPase_1 PF03266.15 PRP82762.1 - 0.033 14.1 0.0 7.9 6.4 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 PRP82762.1 - 0.034 14.5 0.1 3.3 8.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 PRP82762.1 - 0.044 14.3 13.0 0.76 10.2 0.0 3.5 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 PRP82762.1 - 0.063 13.5 0.0 9.2 6.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 PRP82762.1 - 0.069 12.9 0.2 1.4 8.7 0.0 2.8 2 1 0 2 2 2 0 DNA polymerase III, delta subunit MMR_HSR1 PF01926.23 PRP82762.1 - 0.1 12.7 0.0 18 5.4 0.0 3.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF1640 PF07798.11 PRP82762.1 - 1.5 8.8 7.8 3.1 7.8 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) ASF1_hist_chap PF04729.13 PRP82763.1 - 5.7e-47 159.5 0.1 9.7e-47 158.8 0.1 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone F-box PF00646.33 PRP82763.1 - 9.5e-06 25.4 0.3 0.00038 20.2 0.2 3.0 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 PRP82763.1 - 0.00068 19.5 0.1 0.0017 18.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like SURF2 PF05477.11 PRP82763.1 - 0.4 10.3 3.8 0.64 9.7 3.3 1.6 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF1741 PF08427.10 PRP82764.1 - 7.7e-29 101.0 9.1 1.3e-28 100.2 5.8 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1741) Cad PF03596.13 PRP82764.1 - 0.87 9.5 3.7 0.36 10.7 0.2 2.1 3 0 0 3 3 3 0 Cadmium resistance transporter Pro_isomerase PF00160.21 PRP82765.1 - 8.6e-46 156.1 0.0 1e-45 155.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Helitron_like_N PF14214.6 PRP82766.1 - 0.12 12.6 1.5 0.15 12.2 0.3 1.7 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus Qua1 PF16274.5 PRP82766.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.8 2 0 0 2 2 2 0 Qua1 domain RR_TM4-6 PF06459.12 PRP82766.1 - 2.9 7.6 11.0 3.9 7.2 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.32 PRP82767.1 - 0.0022 18.8 0.1 1.9 9.5 0.1 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat V_ATPase_I PF01496.19 PRP82767.1 - 2.6 5.8 5.7 3.7 5.3 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF913 PF06025.12 PRP82767.1 - 3.2 6.6 7.2 4.9 6.0 7.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.6 PRP82767.1 - 4 7.3 22.3 7 6.5 22.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.17 PRP82767.1 - 4.6 7.3 7.0 7.5 6.6 7.0 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 PRP82767.1 - 8.1 5.1 14.0 15 4.2 14.0 1.4 1 0 0 1 1 1 0 Presenilin Brix PF04427.18 PRP82768.1 - 1.6e-22 80.6 0.1 2.4e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 Brix domain DUF1151 PF06625.11 PRP82768.1 - 2.9 7.9 10.2 0.19 11.7 3.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1151) PCI PF01399.27 PRP82771.1 - 9.9e-24 83.9 3.1 1.2e-23 83.6 1.5 2.1 2 0 0 2 2 2 1 PCI domain Vps39_1 PF10366.9 PRP82771.1 - 0.00054 20.2 0.3 0.00054 20.2 0.3 2.9 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 TPR_19 PF14559.6 PRP82771.1 - 0.00087 19.8 0.2 0.0061 17.0 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP82771.1 - 0.0012 19.0 0.5 1.5 9.1 0.0 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat FCH PF00611.23 PRP82771.1 - 0.0025 18.0 1.2 0.022 15.0 0.0 2.7 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain TPR_1 PF00515.28 PRP82771.1 - 0.0078 16.0 11.4 0.66 9.9 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP82771.1 - 0.012 16.3 0.1 15 6.8 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82771.1 - 0.015 15.3 8.3 5 7.5 0.2 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP82771.1 - 0.016 15.3 5.7 0.57 10.5 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_50 PF18024.1 PRP82771.1 - 0.023 14.3 1.1 0.086 12.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain TPR_6 PF13174.6 PRP82771.1 - 0.024 15.3 3.9 30 5.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP82771.1 - 0.031 14.3 4.4 8.6 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP82771.1 - 0.039 13.6 1.5 15 5.4 0.1 3.4 3 0 0 3 3 3 0 TPR repeat LIM PF00412.22 PRP82772.1 - 6.6e-23 80.7 17.8 1.1e-11 44.7 5.1 2.1 2 0 0 2 2 2 2 LIM domain zf-C3HC4_3 PF13920.6 PRP82772.1 - 0.15 11.9 14.6 9 6.3 0.5 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CHCH PF06747.13 PRP82773.1 - 0.041 14.0 2.4 0.064 13.4 2.4 1.3 1 0 0 1 1 1 0 CHCH domain Vps35 PF03635.17 PRP82774.1 - 2.1e-10 39.8 10.5 1.3e-08 33.9 2.5 2.7 1 1 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 RNA_polI_A14 PF08203.11 PRP82774.1 - 0.75 10.6 3.3 2.2 9.1 1.6 2.8 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Rhomboid PF01694.22 PRP82776.1 - 5.9e-10 39.3 5.2 5.9e-10 39.3 5.2 2.9 3 0 0 3 3 3 1 Rhomboid family Anoctamin PF04547.12 PRP82776.1 - 7.7e-07 28.3 0.6 7.7e-07 28.3 0.6 2.3 2 1 0 2 2 2 1 Calcium-activated chloride channel TMC PF07810.13 PRP82776.1 - 9.9e-07 29.3 0.1 9.9e-07 29.3 0.1 2.4 2 0 0 2 2 2 1 TMC domain DER1 PF04511.15 PRP82776.1 - 0.0002 21.3 1.5 0.0002 21.3 1.5 3.5 4 1 0 4 4 4 1 Der1-like family DUF4534 PF15049.6 PRP82776.1 - 0.029 14.1 2.4 0.25 11.1 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) PARP PF00644.20 PRP82777.1 - 2.4e-18 66.4 0.0 3.4e-17 62.7 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Glyco_hydro_18 PF00704.28 PRP82778.1 - 5.9e-13 49.2 2.6 5.9e-13 49.2 2.6 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 HALZ PF02183.18 PRP82778.1 - 0.0015 18.7 0.8 0.0015 18.7 0.8 9.5 9 1 0 9 9 9 2 Homeobox associated leucine zipper Ribosomal_60s PF00428.19 PRP82779.1 - 0.22 12.1 0.2 0.22 12.1 0.2 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF1674 PF07896.12 PRP82780.1 - 2.6e-14 53.4 3.1 4.1e-14 52.8 3.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) CFAP91 PF14738.6 PRP82780.1 - 0.014 15.5 0.6 0.018 15.1 0.6 1.1 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 KfrA_N PF11740.8 PRP82780.1 - 0.024 15.3 0.4 0.032 14.9 0.4 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term NuA4 PF09340.10 PRP82780.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DivIC PF04977.15 PRP82780.1 - 0.31 10.8 2.7 0.42 10.4 2.7 1.2 1 0 0 1 1 1 0 Septum formation initiator IQ PF00612.27 PRP82782.1 - 5.7e-13 47.4 21.4 0.0047 16.6 2.2 5.7 5 0 0 5 5 5 4 IQ calmodulin-binding motif GPHR_N PF12537.8 PRP82782.1 - 0.25 11.4 1.6 3.4 7.8 0.0 4.0 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Guanylate_cyc PF00211.20 PRP82783.1 - 2.6e-64 216.2 0.2 5.3e-35 120.7 0.0 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Peptidase_C78 PF07910.13 PRP82783.1 - 2.2e-53 180.9 0.4 3.9e-53 180.1 0.4 1.4 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 PRP82783.1 - 0.15 11.5 0.4 0.51 9.7 0.0 2.1 3 0 0 3 3 3 0 Peptidase family C54 Halogen_Hydrol PF10112.9 PRP82783.1 - 0.47 10.4 2.9 2.2 8.2 0.2 2.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Nsp1_C PF05064.13 PRP82785.1 - 2.4e-25 88.6 6.2 2.4e-25 88.6 6.2 1.9 2 1 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 PRP82785.1 - 7.8e-07 29.9 174.4 0.00047 20.9 20.0 8.6 1 1 4 6 6 6 3 Nucleoporin FG repeat region Syntaxin PF00804.25 PRP82785.1 - 0.21 11.3 15.0 0.24 11.0 3.8 2.6 1 1 1 2 2 2 0 Syntaxin V_ATPase_I PF01496.19 PRP82785.1 - 0.9 7.4 11.1 1.2 6.9 11.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CTD PF12815.7 PRP82785.1 - 1.3 9.7 106.6 0.52 10.9 1.9 8.9 1 1 1 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Mer2 PF09074.10 PRP82785.1 - 2.6 7.8 12.3 1.5 8.6 9.2 1.8 1 1 0 2 2 2 0 Mer2 Sec34 PF04136.15 PRP82785.1 - 6 6.7 9.5 0.49 10.3 1.8 2.3 1 1 0 2 2 2 0 Sec34-like family DUF1768 PF08719.11 PRP82786.1 - 3.8e-57 193.0 0.3 4.3e-57 192.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tubulin PF00091.25 PRP82787.1 - 8.7e-64 215.4 0.0 1.2e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PRP82787.1 - 4.8e-48 162.5 0.0 7.9e-48 161.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PRP82787.1 - 0.0027 17.4 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain adh_short PF00106.25 PRP82788.1 - 3.7e-15 55.9 0.0 4.8e-14 52.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP82788.1 - 2.9e-06 27.0 0.0 0.00015 21.4 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP82788.1 - 0.017 15.1 0.1 0.81 9.6 0.0 2.2 1 1 1 2 2 2 0 KR domain Nup96 PF12110.8 PRP82789.1 - 1.6e-67 227.7 0.1 3.3e-67 226.7 0.1 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 PRP82789.1 - 4.9e-40 137.1 0.0 8.8e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 PRP82789.1 - 7.5e-07 29.9 205.1 0.0097 16.7 15.8 10.0 3 1 5 8 8 8 4 Nucleoporin FG repeat region tRNA-synt_His PF13393.6 PRP82790.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase RRM_1 PF00076.22 PRP82791.1 - 7.1e-16 57.8 0.1 1.4e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP82791.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Rap_GAP PF02145.15 PRP82793.1 - 5.6e-57 192.3 0.0 1.2e-56 191.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP MORN PF02493.20 PRP82793.1 - 2e-33 112.3 57.8 2.6e-06 27.0 1.9 10.4 11 0 0 11 11 11 9 MORN repeat CH PF00307.31 PRP82793.1 - 5.5e-17 61.9 0.0 1.4e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP82793.1 - 0.0035 17.1 0.0 0.0085 15.9 0.0 1.7 1 0 0 1 1 1 1 CAMSAP CH domain WD40 PF00400.32 PRP82795.1 - 3.3e-43 144.8 16.5 2.2e-08 34.6 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Amino_oxidase PF01593.24 PRP82795.1 - 1.2e-26 94.0 0.9 4.9e-26 92.0 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase ANAPC4_WD40 PF12894.7 PRP82795.1 - 2e-20 72.9 0.1 0.00012 22.3 0.0 5.2 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 PRP82795.1 - 2.8e-16 59.1 0.0 9.1e-16 57.4 0.0 2.0 2 0 0 2 2 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_8 PF13450.6 PRP82795.1 - 1.6e-12 47.5 0.1 3.6e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PRP82795.1 - 3.7e-11 42.8 0.0 4.6e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP82795.1 - 4.8e-11 42.8 0.8 6.6e-06 25.9 1.5 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase RRM_5 PF13893.6 PRP82795.1 - 7.4e-08 32.0 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF2A PF08662.11 PRP82795.1 - 3e-06 27.3 0.0 0.12 12.3 0.0 3.0 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_occluded PF16842.5 PRP82795.1 - 2.9e-05 23.8 0.0 6.7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif FAD_binding_2 PF00890.24 PRP82795.1 - 6.6e-05 22.2 2.2 0.00024 20.3 2.4 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 PRP82795.1 - 9.7e-05 22.9 5.5 0.011 16.2 1.2 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PRP82795.1 - 0.00036 20.0 0.7 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase SpoIIP PF07454.11 PRP82795.1 - 0.0004 19.9 5.5 0.0004 19.9 5.5 2.2 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) NAD_binding_9 PF13454.6 PRP82795.1 - 0.00093 19.2 0.2 0.046 13.7 0.1 3.3 4 0 0 4 4 3 1 FAD-NAD(P)-binding eIF3_subunit PF08597.10 PRP82795.1 - 0.0021 18.0 10.4 0.0021 18.0 10.4 2.3 2 0 0 2 2 1 1 Translation initiation factor eIF3 subunit FAD_binding_3 PF01494.19 PRP82795.1 - 0.0022 17.3 0.2 0.0056 16.0 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 PRP82795.1 - 0.0091 14.9 2.8 1.2 7.9 0.8 2.4 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 PRP82795.1 - 0.0095 15.2 0.3 0.019 14.2 0.3 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 PRP82795.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 PRP82795.1 - 0.018 15.1 0.3 0.31 11.1 0.2 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 PRP82795.1 - 0.021 14.2 0.1 0.052 12.9 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40_like PF17005.5 PRP82795.1 - 0.024 14.0 0.0 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Lycopene_cycl PF05834.12 PRP82795.1 - 0.026 13.6 1.2 0.076 12.0 0.4 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 PRP82795.1 - 0.057 12.1 11.4 0.041 12.6 0.9 3.0 3 0 0 3 3 2 0 HI0933-like protein DDHD PF02862.17 PRP82795.1 - 0.057 13.6 7.9 0.052 13.7 0.3 2.3 2 0 0 2 2 2 0 DDHD domain GDI PF00996.18 PRP82795.1 - 0.057 11.9 0.1 2.1 6.7 0.0 2.3 2 0 0 2 2 2 0 GDP dissociation inhibitor AlaDh_PNT_C PF01262.21 PRP82795.1 - 0.065 12.5 0.5 0.13 11.6 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 PRP82795.1 - 0.066 12.9 0.5 0.18 11.5 0.5 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 PRP82795.1 - 0.078 12.2 0.1 0.078 12.2 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 PRP82795.1 - 0.094 13.0 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 PRP82795.1 - 0.16 12.4 0.0 0.49 10.9 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Trypan_PARP PF05887.11 PRP82795.1 - 7.3 6.6 14.5 19 5.3 14.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PARG_cat PF05028.14 PRP82796.1 - 8.3e-92 308.1 0.1 2.3e-91 306.6 0.1 1.7 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Pkinase_Tyr PF07714.17 PRP82797.1 - 2.9e-63 213.6 0.0 5.1e-63 212.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82797.1 - 8.7e-44 149.9 0.0 1.5e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP82797.1 - 3.6e-36 122.7 107.4 3.7e-06 26.6 3.2 17.9 10 7 8 19 19 19 14 Leucine rich repeat LRR_4 PF12799.7 PRP82797.1 - 3.8e-30 103.4 110.1 7.2e-05 23.1 6.3 20.5 15 5 4 19 19 19 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP82797.1 - 4.7e-07 29.5 81.6 4.9 8.1 0.0 22.9 23 5 0 23 23 23 5 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP82797.1 - 0.18 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LVIVD PF08309.11 PRP82797.1 - 2.8 7.3 5.2 5.8 6.3 0.1 3.7 4 0 0 4 4 4 0 LVIVD repeat PhoLip_ATPase_C PF16212.5 PRP82798.1 - 1.5e-40 139.5 21.2 1.5e-40 139.5 21.2 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP82798.1 - 2e-17 62.6 3.5 2e-17 62.6 3.5 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PRP82798.1 - 5.7e-13 49.6 1.1 2.8e-10 40.8 1.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP82798.1 - 2.7e-11 43.4 0.0 2.1e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 PRP82798.1 - 2.1e-07 30.7 0.0 2.1e-07 30.7 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PRP82798.1 - 0.00022 21.1 0.1 0.00094 19.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 PRP82798.1 - 0.093 12.2 0.4 0.21 11.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) RNase_H PF00075.24 PRP82802.1 - 2.1e-16 60.4 0.0 8.5e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 RNase H RVT_1 PF00078.27 PRP82802.1 - 4.1e-12 46.1 0.0 7.4e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ig_Tie2_1 PF10430.9 PRP82804.1 - 0.00047 20.5 1.4 0.17 12.3 0.1 2.5 2 0 0 2 2 2 2 Tie-2 Ig-like domain 1 DUF3703 PF12487.8 PRP82804.1 - 0.001 18.9 0.7 1 9.2 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3703) DMSP_lyase PF16867.5 PRP82804.1 - 0.048 13.3 0.7 1 9.0 0.3 2.6 2 1 1 3 3 3 0 Dimethlysulfonioproprionate lyase DUF3755 PF12579.8 PRP82804.1 - 0.065 12.9 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) DUF5410 PF17422.2 PRP82804.1 - 0.083 12.1 3.0 2.1 7.5 0.3 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5410) DUF5348 PF17295.2 PRP82804.1 - 0.31 11.0 2.7 5.3 7.0 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) DUF3785 PF12653.7 PRP82804.1 - 0.8 9.8 6.1 2.6 8.2 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3785) Aldedh PF00171.22 PRP82805.1 - 4.3e-150 500.3 0.0 6.5e-150 499.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 PRP82805.1 - 0.001 18.5 0.1 0.0035 16.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1487) LEA_4 PF02987.16 PRP82806.1 - 3.3e-35 119.9 179.7 2.4e-08 33.9 12.8 12.4 3 3 9 12 12 12 11 Late embryogenesis abundant protein Apolipoprotein PF01442.18 PRP82806.1 - 7.9e-07 29.1 92.2 0.00047 20.1 34.0 4.9 1 1 1 3 3 3 3 Apolipoprotein A1/A4/E domain YtxH PF12732.7 PRP82806.1 - 0.00012 22.5 129.2 0.43 11.1 12.1 10.0 1 1 4 5 5 5 1 YtxH-like protein DUF883 PF05957.13 PRP82806.1 - 0.43 11.2 112.9 1 10.0 10.9 9.1 2 1 9 11 11 11 0 Bacterial protein of unknown function (DUF883) RGS PF00615.19 PRP82808.1 - 7.8e-21 74.5 3.8 1.4e-20 73.7 3.8 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain TyeA PF09059.10 PRP82808.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 TyeA THDPS_N_2 PF14805.6 PRP82808.1 - 0.15 12.3 0.4 0.93 9.8 0.2 2.3 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal rve PF00665.26 PRP82810.1 - 3.4e-06 27.2 0.0 5.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF3127 PF11325.8 PRP82814.1 - 0.066 13.5 0.1 0.076 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) TPD52 PF04201.15 PRP82817.1 - 0.063 12.9 1.7 0.21 11.2 1.7 1.9 1 1 0 1 1 1 0 Tumour protein D52 family CC2-LZ PF16516.5 PRP82817.1 - 0.2 12.0 6.8 0.23 11.8 2.0 2.4 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TINF2_N PF14973.6 PRP82817.1 - 4.2 7.7 7.0 6.3 7.1 0.0 2.7 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus HAD_2 PF13419.6 PRP82817.1 - 6.4 6.8 7.0 0.46 10.5 0.9 2.2 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase DUF3348 PF11828.8 PRP82817.1 - 8.1 6.0 11.8 0.23 11.1 4.9 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3348) B5 PF03484.15 PRP82818.1 - 0.055 13.8 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetase B5 domain PhoQ_Sensor PF08918.10 PRP82818.1 - 0.062 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoQ Sensor Dimer_Tnp_hAT PF05699.14 PRP82819.1 - 0.052 13.3 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Pox_Ag35 PF03286.14 PRP82822.1 - 4.9 6.9 8.9 1.3 8.7 5.6 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Ank_2 PF12796.7 PRP82823.1 - 1.1e-05 26.0 0.0 8.5e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box_4 PF15966.5 PRP82823.1 - 2.1e-05 24.3 0.0 5.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box Ank_5 PF13857.6 PRP82823.1 - 7.5e-05 22.9 0.0 0.35 11.2 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82823.1 - 0.0001 22.4 0.0 0.52 11.1 0.0 4.9 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 PRP82823.1 - 0.0011 19.4 0.0 25 5.6 0.0 4.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 PRP82823.1 - 0.046 14.2 0.0 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat CENP-U PF13097.6 PRP82823.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit F-box-like PF12937.7 PRP82823.1 - 0.091 12.7 0.2 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 PRP82824.1 - 0.003 17.4 0.1 0.0072 16.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP82824.1 - 0.093 12.6 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 F-box domain DDE_Tnp_1_7 PF13843.6 PRP82826.1 - 5e-06 26.1 0.0 1.8e-05 24.2 0.0 1.8 1 1 1 2 2 2 1 Transposase IS4 SAND PF01342.21 PRP82826.1 - 0.16 11.7 1.1 0.29 10.9 1.1 1.3 1 0 0 1 1 1 0 SAND domain WcbI PF18588.1 PRP82826.1 - 0.66 9.6 4.3 2.2 7.8 1.6 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI Ank_2 PF12796.7 PRP82827.1 - 1.2e-05 25.8 0.0 8.8e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box_4 PF15966.5 PRP82827.1 - 2.2e-05 24.3 0.0 5.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box Ank_5 PF13857.6 PRP82827.1 - 6.8e-05 23.1 0.0 0.36 11.2 0.0 5.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82827.1 - 0.00012 22.2 0.0 0.53 11.0 0.0 4.9 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 PRP82827.1 - 0.0013 19.2 0.0 26 5.5 0.0 4.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 PRP82827.1 - 0.048 14.1 0.0 0.24 11.9 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat F-box-like PF12937.7 PRP82827.1 - 0.094 12.6 0.2 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 F-box-like Podoplanin PF05808.11 PRP82828.1 - 0.0002 21.5 0.2 0.00031 20.9 0.2 1.2 1 0 0 1 1 1 1 Podoplanin FA_desaturase PF00487.24 PRP82828.1 - 0.072 12.9 5.1 0.11 12.3 5.1 1.3 1 0 0 1 1 1 0 Fatty acid desaturase MgtE PF01769.16 PRP82828.1 - 1.6 9.1 12.2 5.1 7.5 8.9 2.5 2 0 0 2 2 2 0 Divalent cation transporter DUF4577 PF15145.6 PRP82828.1 - 3.9 7.5 4.7 27 4.8 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Motile_Sperm PF00635.26 PRP82829.1 - 3.1e-17 62.4 1.2 1.3e-16 60.4 1.2 2.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain F-box PF00646.33 PRP82829.1 - 1.5e-10 40.7 0.7 3.2e-10 39.6 0.7 1.6 1 0 0 1 1 1 1 F-box domain SPT2 PF08243.11 PRP82829.1 - 1.8e-09 38.1 21.5 1.8e-09 38.1 21.5 6.3 6 1 0 7 7 7 1 SPT2 chromatin protein F-box-like PF12937.7 PRP82829.1 - 1.2e-06 28.2 0.9 2.7e-06 27.1 0.9 1.6 1 0 0 1 1 1 1 F-box-like Glyco_hydro_38C PF07748.13 PRP82830.1 - 0.028 14.5 1.6 0.032 14.3 1.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain DUF3807 PF12720.7 PRP82830.1 - 0.17 12.2 8.5 0.32 11.3 7.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3807) Trnau1ap PF17654.1 PRP82830.1 - 5.1 8.0 16.9 6.5 7.7 17.0 1.3 1 1 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins CRCB PF02537.15 PRP82832.1 - 8.6e-35 118.9 15.6 2.1e-17 63.2 5.6 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF3537 PF12056.8 PRP82832.1 - 0.0015 17.5 0.1 0.0028 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3537) DUF4231 PF14015.6 PRP82832.1 - 0.007 16.8 3.1 0.047 14.2 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) Pkinase_Tyr PF07714.17 PRP82834.1 - 8.4e-67 225.2 0.0 1.2e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82834.1 - 1.2e-43 149.4 0.0 1.8e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PRP82834.1 - 0.0043 16.0 0.0 0.014 14.4 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Sh_2 PF17512.2 PRP82834.1 - 0.11 12.3 0.9 1.9 8.2 0.2 2.2 2 0 0 2 2 2 0 Metapneumovirus Small hydrophobic protein Bac_rhodopsin PF01036.18 PRP82835.1 - 2.9e-12 46.7 6.2 3.4e-12 46.4 6.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein TIG PF01833.24 PRP82836.1 - 1.8e-137 447.7 424.3 4e-10 39.6 5.0 31.4 28 4 4 32 32 31 28 IPT/TIG domain Pkinase_Tyr PF07714.17 PRP82836.1 - 1.4e-69 234.3 0.0 1.9e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82836.1 - 6e-48 163.5 0.0 9.3e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP82836.1 - 4e-08 32.9 5.3 0.00017 21.3 0.2 3.1 1 1 1 2 2 2 2 Leucine rich repeat PAN_4 PF14295.6 PRP82836.1 - 2e-05 24.4 0.6 5.5e-05 23.0 0.6 1.8 1 0 0 1 1 1 1 PAN domain Kdo PF06293.14 PRP82836.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E1B_55K PF01696.17 PRP82836.1 - 0.0037 16.0 3.0 0.0038 16.0 1.4 1.8 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen Pkinase_fungal PF17667.1 PRP82836.1 - 0.0065 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_11 PF18831.1 PRP82836.1 - 0.0077 15.8 1.0 0.11 12.0 1.0 3.2 1 0 0 1 1 1 1 Leucine-rich repeat PAN_2 PF08276.11 PRP82836.1 - 0.022 14.9 0.9 0.06 13.5 0.9 1.7 1 0 0 1 1 1 0 PAN-like domain LRR_4 PF12799.7 PRP82836.1 - 0.046 14.2 11.0 1.7 9.2 0.3 4.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) MobC PF05713.11 PRP82836.1 - 0.1 13.1 0.6 0.27 11.7 0.6 1.6 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) WD40 PF00400.32 PRP82838.1 - 3.9e-44 147.7 36.0 5.8e-06 27.0 0.6 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat CHAP PF05257.16 PRP82838.1 - 0.005 17.4 11.7 6.4 7.4 0.1 5.8 1 1 4 5 5 5 1 CHAP domain SnoaL_2 PF12680.7 PRP82838.1 - 0.0051 17.4 3.3 3.1 8.5 0.0 4.1 2 2 2 4 4 4 1 SnoaL-like domain 3A PF00803.18 PRP82838.1 - 0.0082 15.5 8.2 1.4 8.2 0.1 4.0 1 1 3 5 5 5 3 3A/RNA2 movement protein family Read-through PF16814.5 PRP82838.1 - 0.013 15.3 4.9 12 5.6 0.0 4.6 1 1 5 6 6 6 0 Read-through domain LAT PF15234.6 PRP82838.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells BPL_C PF02237.17 PRP82838.1 - 0.08 12.9 0.0 1e+02 2.9 0.0 4.6 4 2 1 5 5 5 0 Biotin protein ligase C terminal domain Aldo_ket_red PF00248.21 PRP82839.1 - 1.3e-66 224.8 0.0 1.4e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GCIP PF13324.6 PRP82839.1 - 0.14 11.7 0.1 0.67 9.5 0.2 1.9 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting TPR_1 PF00515.28 PRP82840.1 - 4.9e-42 140.1 17.7 1.2e-08 34.4 0.2 8.9 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82840.1 - 1.5e-37 124.6 18.6 8.5e-06 25.5 0.1 9.6 9 1 1 10 10 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 PRP82840.1 - 3.3e-25 86.2 9.0 0.00026 21.0 0.1 8.5 8 1 0 8 8 8 5 Tetratricopeptide repeat DnaJ PF00226.31 PRP82840.1 - 2e-23 82.2 8.4 4e-23 81.3 7.1 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 PRP82840.1 - 3.8e-22 78.6 15.7 0.0002 21.8 0.0 7.5 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 PRP82840.1 - 5.6e-22 77.1 16.8 0.00053 19.6 0.8 8.4 4 3 4 8 8 8 6 TPR repeat TPR_14 PF13428.6 PRP82840.1 - 4.2e-20 70.7 5.7 0.00033 21.2 0.0 8.7 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 PRP82840.1 - 5.1e-17 61.0 12.3 0.00017 21.7 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 PRP82840.1 - 1.6e-16 60.3 18.0 0.00051 20.3 0.7 7.8 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 PRP82840.1 - 3.5e-15 56.4 5.5 0.071 13.8 0.2 6.9 4 2 4 8 8 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 PRP82840.1 - 7.3e-14 50.7 2.7 0.0029 17.5 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 PRP82840.1 - 1.3e-12 47.7 0.1 0.0039 17.3 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP82840.1 - 2.3e-10 40.4 10.0 0.055 14.1 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP82840.1 - 1.2e-08 35.0 14.5 0.017 15.3 0.4 6.1 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 PRP82840.1 - 4e-07 29.7 2.8 1.4e-05 24.7 0.4 3.2 2 1 2 4 4 4 1 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 PRP82840.1 - 3.1e-05 23.9 15.2 4.8 7.3 0.0 6.7 7 1 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 PRP82840.1 - 0.00011 22.0 15.1 0.0081 16.0 0.0 6.0 7 0 0 7 7 6 1 Tetratricopeptide repeat BTAD PF03704.17 PRP82840.1 - 0.00022 21.7 5.8 0.77 10.2 0.7 4.3 1 1 1 3 3 3 1 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 PRP82840.1 - 0.00033 20.1 2.4 4.2 6.9 0.0 4.4 4 0 0 4 4 4 1 SHNi-TPR DUF3856 PF12968.7 PRP82840.1 - 0.0011 19.0 6.0 3.3 7.8 0.5 6.1 6 1 0 6 6 6 1 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 PRP82840.1 - 0.0016 18.9 6.6 0.94 9.9 0.2 4.5 2 2 2 4 4 4 1 Alkyl sulfatase dimerisation HemY_N PF07219.13 PRP82840.1 - 0.0094 16.1 5.8 5.4 7.3 0.2 3.7 3 1 0 3 3 3 1 HemY protein N-terminus MIT PF04212.18 PRP82840.1 - 0.11 12.5 25.5 0.71 10.0 0.3 6.0 8 0 0 8 8 6 0 MIT (microtubule interacting and transport) domain TPM_phosphatase PF04536.14 PRP82840.1 - 0.21 11.8 1.7 0.87 9.8 0.1 2.7 3 0 0 3 3 3 0 TPM domain RasGEF PF00617.19 PRP82841.1 - 5.3e-49 166.8 0.1 1.5e-48 165.4 0.1 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP82841.1 - 0.0057 16.9 1.3 0.035 14.3 0.0 2.9 3 0 0 3 3 3 1 RasGEF N-terminal motif Herpes_glycop_D PF01537.17 PRP82842.1 - 0.0076 16.4 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 Herpesvirus glycoprotein D/GG/GX domain Pkinase PF00069.25 PRP82843.1 - 1.8e-72 243.9 0.0 2.2e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82843.1 - 2.3e-34 118.9 0.0 5.4e-33 114.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP82843.1 - 2.6e-10 40.1 0.1 6.5e-06 25.7 0.0 2.7 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 PRP82843.1 - 0.0005 20.1 0.0 0.22 11.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP82843.1 - 0.022 13.7 0.0 0.045 12.7 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PRP82843.1 - 0.041 13.2 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family VCPO_N PF17897.1 PRP82843.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain Iso_dh PF00180.20 PRP82844.1 - 1.1e-78 264.9 0.0 1.4e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_transf_56 PF07429.11 PRP82844.1 - 0.0035 16.5 0.0 0.0053 15.9 0.0 1.1 1 0 0 1 1 1 1 4-alpha-L-fucosyltransferase glycosyl transferase group 56 TPR_1 PF00515.28 PRP82845.1 - 0.00014 21.5 5.5 0.35 10.8 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP82845.1 - 0.00047 19.8 0.2 0.0012 18.5 0.2 1.7 1 0 0 1 1 1 1 TPR repeat Methyltransf_25 PF13649.6 PRP82845.1 - 0.0012 19.5 0.0 0.011 16.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain TPR_16 PF13432.6 PRP82845.1 - 0.0019 18.8 1.4 0.68 10.6 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat NYD-SP12_N PF15015.6 PRP82845.1 - 0.0024 16.3 0.1 0.0045 15.4 0.1 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal Methyltransf_23 PF13489.6 PRP82845.1 - 0.0025 17.7 0.4 0.034 14.0 0.0 2.8 3 1 0 3 3 3 1 Methyltransferase domain TPR_2 PF07719.17 PRP82845.1 - 0.0045 17.0 7.0 0.12 12.5 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP82845.1 - 0.0053 17.0 2.3 0.029 14.6 1.2 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP82845.1 - 0.018 15.5 1.4 0.61 10.6 0.4 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP82845.1 - 0.028 15.2 0.7 4.9 8.2 0.0 3.8 3 1 1 4 4 2 0 Tetratricopeptide repeat Methyltransf_12 PF08242.12 PRP82845.1 - 0.045 14.5 0.0 0.2 12.4 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain TPR_12 PF13424.6 PRP82845.1 - 0.095 13.0 2.1 0.37 11.1 0.2 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat Z1 PF10593.9 PRP82845.1 - 0.1 12.1 0.1 0.21 11.1 0.1 1.5 1 0 0 1 1 1 0 Z1 domain SLATT_fungal PF18142.1 PRP82846.1 - 0.018 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain Neurensin PF14927.6 PRP82846.1 - 0.29 10.9 0.0 0.29 10.9 0.0 2.4 2 1 0 2 2 2 0 Neurensin SNF2_N PF00176.23 PRP82848.1 - 7.8e-37 126.8 0.1 1.5e-36 125.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 PRP82848.1 - 5.2e-10 39.6 0.0 1.3e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP82848.1 - 9.9e-10 38.8 0.1 2.4e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PRP82848.1 - 0.12 12.6 0.0 0.87 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DDHD PF02862.17 PRP82848.1 - 0.19 11.9 6.0 0.14 12.3 1.3 2.3 2 0 0 2 2 2 0 DDHD domain Uds1 PF15456.6 PRP82848.1 - 7 6.8 8.3 1.3 9.2 0.7 3.0 3 0 0 3 3 3 0 Up-regulated During Septation Pkinase_Tyr PF07714.17 PRP82849.1 - 2.5e-26 92.5 0.8 3.5e-23 82.2 0.6 3.2 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 PRP82849.1 - 2.6e-26 91.1 59.9 1.8e-05 24.4 6.2 9.4 8 1 1 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 PRP82849.1 - 3.6e-25 87.6 65.3 6.5e-05 23.2 1.8 10.7 8 2 3 11 11 11 8 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP82849.1 - 1.8e-15 57.0 0.1 1e-14 54.6 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 PRP82849.1 - 5.4e-13 49.3 2.2 0.00011 22.7 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) GPS PF01825.21 PRP82849.1 - 3.3e-09 37.1 3.1 3.3e-09 37.1 3.1 2.4 2 0 0 2 2 1 1 GPCR proteolysis site, GPS, motif Ank_3 PF13606.6 PRP82849.1 - 2.6e-06 27.3 0.6 7 7.6 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 PRP82849.1 - 6e-06 26.7 9.0 0.024 15.2 0.0 5.5 4 2 2 6 6 5 2 Ankyrin repeats (many copies) LRR_1 PF00560.33 PRP82849.1 - 3.9e-05 23.6 58.7 1.7 9.5 0.4 15.3 15 2 0 15 15 14 5 Leucine Rich Repeat F-box PF00646.33 PRP82849.1 - 0.011 15.5 0.0 0.044 13.7 0.0 2.1 1 0 0 1 1 1 0 F-box domain LRRNT_2 PF08263.12 PRP82849.1 - 0.095 13.0 6.6 0.47 10.8 0.4 3.5 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PRP82849.1 - 2 8.7 46.1 3.9 7.8 0.6 10.8 11 0 0 11 11 10 0 Leucine Rich repeat TIG PF01833.24 PRP82850.1 - 1.2e-09 38.2 0.0 5.2e-09 36.1 0.0 2.0 2 1 1 3 3 3 1 IPT/TIG domain Mrr_cat PF04471.12 PRP82850.1 - 0.064 13.3 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease ATP-synt_C PF00137.21 PRP82851.1 - 6.2e-36 122.5 34.5 1.6e-22 79.6 11.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Glycophorin_A PF01102.18 PRP82851.1 - 0.41 10.9 2.8 0.81 9.9 2.8 1.4 1 0 0 1 1 1 0 Glycophorin A Man-6-P_recep PF02157.15 PRP82851.1 - 6 5.9 4.9 0.84 8.7 0.1 1.8 2 0 0 2 2 2 0 Mannose-6-phosphate receptor WRKY PF03106.15 PRP82852.1 - 0.093 13.0 0.6 0.21 11.8 0.6 1.6 1 0 0 1 1 1 0 WRKY DNA -binding domain HSA PF07529.13 PRP82852.1 - 0.29 11.5 2.8 0.25 11.7 0.3 2.2 2 0 0 2 2 2 0 HSA CLU PF13236.6 PRP82853.1 - 7.9e-49 166.5 0.0 1.7e-48 165.4 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria TPR_17 PF13431.6 PRP82853.1 - 2.9e-11 42.9 8.0 0.017 15.5 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 PRP82853.1 - 1.7e-09 37.9 0.2 4.3e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 PRP82853.1 - 8.6e-09 35.6 2.7 0.0017 18.6 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP82853.1 - 1.1e-06 29.0 0.9 0.12 12.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCHH PF10283.9 PRP82853.1 - 2.5e-06 27.3 2.3 5.2e-06 26.3 2.3 1.5 1 0 0 1 1 1 1 PBZ domain TPR_16 PF13432.6 PRP82853.1 - 1.7e-05 25.4 0.7 0.0075 16.9 0.0 3.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82853.1 - 0.00037 20.4 7.2 0.71 10.1 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP82853.1 - 0.0025 17.6 0.8 0.021 14.7 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP82853.1 - 0.005 16.5 2.6 2.6 7.8 0.1 3.4 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 PRP82853.1 - 0.068 13.4 6.0 28 5.3 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP82853.1 - 0.29 11.0 3.0 11 6.0 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CSN8_PSD8_EIF3K PF10075.9 PRP82855.1 - 3.3e-22 79.0 0.4 4.5e-22 78.6 0.4 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 PRP82855.1 - 0.028 14.9 1.3 0.057 13.9 0.3 2.0 2 0 0 2 2 2 0 PCI domain SAC3_GANP PF03399.16 PRP82855.1 - 0.037 13.4 0.9 0.037 13.4 0.2 1.4 2 0 0 2 2 2 0 SAC3/GANP family HTH_26 PF13443.6 PRP82855.1 - 0.19 12.2 0.8 27 5.3 0.0 2.8 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain Nt_Gln_amidase PF09764.9 PRP82857.1 - 0.0023 17.6 0.3 0.0037 16.9 0.2 1.5 1 1 1 2 2 2 1 N-terminal glutamine amidase PDZ_1 PF12812.7 PRP82857.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 PDZ-like domain DOPA_dioxygen PF08883.11 PRP82858.1 - 3.9e-23 81.7 0.9 7.1e-23 80.8 0.9 1.4 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family GrpB PF04229.14 PRP82858.1 - 0.078 13.2 0.9 1.8 8.7 0.1 2.0 1 1 0 2 2 2 0 GrpB protein PDEase_II PF02112.15 PRP82859.1 - 9.7e-48 163.0 0.0 2.5e-47 161.6 0.0 1.6 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II PAN_4 PF14295.6 PRP82859.1 - 1.9e-09 37.3 4.5 6e-09 35.7 4.5 2.0 1 0 0 1 1 1 1 PAN domain Glyco_hydro_16 PF00722.21 PRP82859.1 - 2.8e-06 26.9 0.0 5.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAN_1 PF00024.26 PRP82859.1 - 0.00027 20.9 1.4 0.00067 19.6 1.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP82859.1 - 0.046 13.9 5.0 0.14 12.3 5.0 1.8 1 0 0 1 1 1 0 PAN-like domain ASC PF00858.24 PRP82860.1 - 4.1e-07 29.3 2.5 0.0092 15.0 0.2 2.2 2 0 0 2 2 2 2 Amiloride-sensitive sodium channel Lig_chan PF00060.26 PRP82860.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel PLDc_2 PF13091.6 PRP82861.1 - 3.8e-41 140.1 0.1 2.1e-27 95.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 PRP82861.1 - 1.6e-09 37.5 1.7 0.00082 19.5 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Transketolase_C PF02780.20 PRP82861.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain SH2_2 PF14633.6 PRP82862.1 - 4.9e-65 219.0 1.2 1.1e-64 217.8 1.2 1.5 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 PRP82862.1 - 2.7e-27 95.4 0.0 7.5e-27 94.0 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 PRP82862.1 - 4e-19 68.9 0.1 8.7e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 PRP82862.1 - 8.4e-17 61.7 1.0 3.7e-16 59.6 1.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 PRP82862.1 - 1.5e-10 41.5 11.7 1.5e-10 41.5 11.7 3.8 3 1 1 4 4 4 1 Acidic N-terminal SPT6 Tex_YqgF PF16921.5 PRP82862.1 - 3.6e-06 27.5 0.0 7.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain S1 PF00575.23 PRP82862.1 - 0.0016 18.8 0.1 0.0038 17.5 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_9 PF17674.1 PRP82862.1 - 0.0022 18.9 0.1 0.0091 16.9 0.0 2.2 2 0 0 2 2 2 1 HHH domain L27_2 PF09045.10 PRP82862.1 - 0.033 14.1 0.4 0.092 12.7 0.4 1.7 1 0 0 1 1 1 0 L27_2 NOP19 PF10863.8 PRP82862.1 - 0.071 12.9 0.1 0.23 11.3 0.1 1.8 1 0 0 1 1 1 0 Nucleolar protein 19 DUF4690 PF15756.5 PRP82864.1 - 0.0089 16.6 0.4 0.026 15.1 0.4 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 PRP82864.1 - 0.19 11.8 3.5 0.22 11.6 1.9 1.9 2 0 0 2 2 2 0 Podoplanin Kelch_4 PF13418.6 PRP82865.1 - 3e-30 104.0 6.0 6.5e-06 26.1 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP82865.1 - 6.4e-27 92.9 3.2 7.7e-07 29.2 0.0 5.6 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 PRP82865.1 - 6.6e-27 93.2 11.1 2.7e-07 30.7 0.0 7.4 7 1 1 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP82865.1 - 8.9e-25 86.2 4.1 5.9e-08 32.5 0.1 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PRP82865.1 - 2.4e-19 68.7 2.4 7.9e-06 25.4 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 PRP82865.1 - 2.5e-19 68.4 1.0 3.7e-08 33.0 0.0 5.7 6 0 0 6 6 6 4 Kelch motif FA_desaturase PF00487.24 PRP82866.1 - 7.7e-23 81.6 16.9 7.7e-23 81.6 16.9 2.7 3 0 0 3 3 3 1 Fatty acid desaturase Glyco_tranf_2_3 PF13641.6 PRP82866.1 - 3.5e-11 43.4 0.0 8.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 G-patch PF01585.23 PRP82866.1 - 5.3e-11 42.2 1.8 1.1e-10 41.3 1.8 1.6 1 0 0 1 1 1 1 G-patch domain PH PF00169.29 PRP82866.1 - 5.5e-10 39.7 0.0 2.3e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 PH domain Glyco_trans_2_3 PF13632.6 PRP82866.1 - 2.4e-08 34.2 4.1 1e-07 32.1 4.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 F-box-like PF12937.7 PRP82866.1 - 3.8e-07 29.9 0.4 1.5e-06 28.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like DUF3474 PF11960.8 PRP82866.1 - 4.4e-07 30.2 0.0 4.4e-07 30.2 0.0 3.7 3 0 0 3 3 2 1 Domain of unknown function (DUF3474) F-box PF00646.33 PRP82866.1 - 6.7e-06 25.8 0.3 3.3e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 F-box domain G-patch_2 PF12656.7 PRP82866.1 - 1.4e-05 25.1 0.4 5.4e-05 23.2 0.4 2.1 1 0 0 1 1 1 1 G-patch domain Glycos_transf_2 PF00535.26 PRP82866.1 - 2.1e-05 24.4 0.0 0.0001 22.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 PH_11 PF15413.6 PRP82866.1 - 2.4e-05 24.7 0.1 0.00017 21.9 0.1 2.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ku_PK_bind PF08785.11 PRP82866.1 - 0.11 12.6 1.1 0.59 10.3 0.3 2.8 2 0 0 2 2 2 0 Ku C terminal domain like TarH PF02203.15 PRP82866.1 - 1 9.3 5.5 0.92 9.4 0.1 3.4 4 0 0 4 4 4 0 Tar ligand binding domain homologue Homeodomain PF00046.29 PRP82868.1 - 2e-10 40.4 9.6 2.5e-05 24.0 1.9 2.8 3 0 0 3 3 3 2 Homeodomain MerR_1 PF13411.6 PRP82868.1 - 0.00012 22.1 1.1 0.014 15.5 0.2 2.3 2 0 0 2 2 2 1 MerR HTH family regulatory protein Radical_SAM_C PF16199.5 PRP82868.1 - 0.00051 20.0 0.1 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 Radical_SAM C-terminal domain PMD PF10536.9 PRP82868.1 - 0.011 14.9 1.7 0.013 14.6 1.2 1.3 1 1 0 1 1 1 0 Plant mobile domain HTH_Tnp_1 PF01527.20 PRP82868.1 - 0.04 14.2 3.5 1.7 9.0 0.1 2.9 3 1 0 3 3 3 0 Transposase Homeobox_KN PF05920.11 PRP82868.1 - 0.06 13.3 5.4 1.1 9.3 2.1 2.6 2 0 0 2 2 2 0 Homeobox KN domain zf-dskA_traR PF01258.17 PRP82868.1 - 0.084 12.8 0.6 0.17 11.9 0.6 1.4 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger HTH_28 PF13518.6 PRP82868.1 - 0.089 12.9 0.4 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HATPase_c PF02518.26 PRP82869.1 - 1.2e-25 90.2 0.5 2.8e-25 89.0 0.2 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP82869.1 - 9.6e-21 74.0 0.8 1.7e-15 57.2 0.2 3.4 3 0 0 3 3 3 2 Response regulator receiver domain Bac_rhodopsin PF01036.18 PRP82869.1 - 1.3e-16 60.8 15.8 2.3e-16 60.1 15.8 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HisKA PF00512.25 PRP82869.1 - 3.4e-13 49.4 0.2 1e-12 47.9 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CrgA PF06781.12 PRP82869.1 - 0.013 15.5 0.0 0.054 13.6 0.0 2.0 1 0 0 1 1 1 0 Cell division protein CrgA Costars PF14705.6 PRP82870.1 - 4e-22 78.2 0.1 4.8e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 Costars Chordopox_A13L PF05961.11 PRP82871.1 - 0.084 13.1 0.1 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 Chordopoxvirus A13L protein Integrin_beta PF00362.18 PRP82871.1 - 0.22 11.1 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Integrin beta chain VWA domain DUF4389 PF14333.6 PRP82871.1 - 2.4 8.1 7.4 2.3 8.2 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) START PF01852.19 PRP82872.1 - 2e-10 40.4 0.0 7.7e-10 38.5 0.0 1.7 1 1 1 2 2 2 1 START domain rRNA_proc-arch PF13234.6 PRP82873.1 - 3.4e-75 253.5 1.2 6.4e-75 252.6 1.2 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 PRP82873.1 - 3.6e-51 173.1 0.4 3.6e-51 173.1 0.4 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 PRP82873.1 - 1.1e-16 61.2 0.0 3.8e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP82873.1 - 7.2e-08 32.8 0.0 3.8e-06 27.2 0.0 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain XhlA PF10779.9 PRP82873.1 - 0.44 10.8 2.5 1.6 9.0 2.5 2.0 1 0 0 1 1 1 0 Haemolysin XhlA Tfb4 PF03850.14 PRP82874.1 - 3.8e-82 275.9 2.1 2.5e-81 273.2 2.1 1.8 1 1 0 1 1 1 1 Transcription factor Tfb4 CRIM PF16978.5 PRP82875.1 - 1.6e-11 44.5 0.0 4e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain RBD PF02196.15 PRP82875.1 - 1.5e-10 41.0 0.1 1.5e-05 25.0 0.0 2.7 3 0 0 3 3 3 2 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 PRP82875.1 - 8.3e-05 22.7 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 2 TUG ubiquitin-like domain RA PF00788.23 PRP82875.1 - 0.029 15.0 0.0 0.16 12.6 0.0 2.3 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain CHGN PF05679.16 PRP82875.1 - 0.32 9.8 3.1 0.15 10.9 0.3 1.7 2 0 0 2 2 2 0 Chondroitin N-acetylgalactosaminyltransferase PMM PF03332.13 PRP82876.1 - 1.1e-100 336.0 1.8 1.2e-100 335.8 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 PRP82876.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PRP82876.1 - 0.0032 17.0 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 PRP82876.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.9 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP82876.1 - 0.079 13.2 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NitrOD1 PF18549.1 PRP82876.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 WD40 PF00400.32 PRP82877.1 - 6.8e-23 80.5 9.9 9e-06 26.3 1.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP82877.1 - 7.1e-12 45.5 0.1 0.0085 16.4 0.0 5.9 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP82877.1 - 0.00013 21.9 0.0 0.099 12.5 0.0 3.3 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PRP82877.1 - 0.014 14.4 0.6 14 4.5 0.0 4.2 2 2 3 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4446 PF14584.6 PRP82877.1 - 0.69 9.9 0.0 0.69 9.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) zf-MYND PF01753.18 PRP82878.1 - 9.2e-08 32.1 14.8 2.1e-07 30.9 14.8 1.6 1 0 0 1 1 1 1 MYND finger Neugrin PF06413.11 PRP82878.1 - 0.012 15.6 0.4 0.012 15.6 0.4 2.0 3 0 0 3 3 3 0 Neugrin VitK2_biosynth PF02621.14 PRP82878.1 - 0.088 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Menaquinone biosynthesis Helitron_like_N PF14214.6 PRP82878.1 - 0.089 13.0 0.2 0.26 11.5 0.2 1.9 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus ubiquitin PF00240.23 PRP82879.1 - 4.6e-26 90.4 0.6 6.4e-26 89.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP82879.1 - 4e-14 52.2 1.6 4.8e-14 51.9 1.1 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP82879.1 - 7.5e-06 26.3 1.4 1.7e-05 25.2 0.3 2.1 3 1 0 3 3 3 1 Ubiquitin-like domain TBK1_ULD PF18396.1 PRP82879.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain SPC22 PF04573.12 PRP82881.1 - 7.4e-36 123.2 0.1 1.2e-35 122.5 0.1 1.3 1 1 0 1 1 1 1 Signal peptidase subunit PH PF00169.29 PRP82882.1 - 1.6e-09 38.2 0.7 9.9e-09 35.7 0.7 2.2 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP82882.1 - 0.0034 17.8 2.1 0.0086 16.5 2.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain COX5B PF01215.19 PRP82883.1 - 1.4e-12 47.4 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb NAD_binding_2 PF03446.15 PRP82884.1 - 1.1e-46 158.9 1.7 1.8e-46 158.2 1.7 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PRP82884.1 - 6.6e-34 116.8 0.0 1.3e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 PRP82884.1 - 2.3e-05 23.8 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 PRP82884.1 - 3.5e-05 24.3 0.0 9.1e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 PRP82884.1 - 0.00028 20.8 0.2 0.0008 19.3 0.1 1.8 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 PRP82884.1 - 0.0015 18.1 0.3 0.042 13.4 0.0 2.2 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PDH PF02153.17 PRP82884.1 - 0.0072 15.4 0.2 0.01 14.9 0.2 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase TrkA_N PF02254.18 PRP82884.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 PRP82884.1 - 0.021 14.9 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 PRP82884.1 - 0.03 14.3 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 PRP82884.1 - 0.049 13.9 0.2 0.42 10.9 0.2 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 PRP82884.1 - 0.094 12.4 0.1 0.19 11.4 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_16 PF10294.9 PRP82885.1 - 3.3e-15 56.2 0.0 1.4e-11 44.4 0.0 2.1 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 PRP82885.1 - 0.0097 16.6 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP82885.1 - 0.065 13.9 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 PRP82885.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain ABM PF03992.16 PRP82886.1 - 0.00035 20.6 1.8 0.035 14.2 0.0 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase AIRC PF00731.20 PRP82888.1 - 1.8e-58 196.3 0.2 3.8e-58 195.3 0.2 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 PRP82888.1 - 6.6e-58 195.1 0.2 1e-57 194.4 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 PRP82888.1 - 7.1e-09 35.2 1.6 8.7e-09 34.9 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 PRP82888.1 - 1.6e-07 31.0 0.6 4.5e-07 29.6 0.6 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.19 PRP82888.1 - 0.0088 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GARS_A PF01071.19 PRP82888.1 - 0.02 14.7 0.2 0.046 13.5 0.1 1.6 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PALP PF00291.25 PRP82888.1 - 0.055 12.9 0.2 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme LBP_BPI_CETP_C PF02886.17 PRP82889.1 - 7.3e-33 114.0 2.0 2.3e-32 112.3 0.0 2.1 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 PRP82889.1 - 3.1e-17 62.7 0.2 6.6e-17 61.6 0.2 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.11 PRP82889.1 - 0.016 14.4 0.5 0.025 13.8 0.5 1.3 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF1887 PF09002.11 PRP82889.1 - 0.093 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Lectin_leg-like PF03388.13 PRP82890.1 - 2e-38 132.0 0.0 3.7e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Legume-like lectin family EGF_2 PF07974.13 PRP82890.1 - 0.00062 20.1 12.3 0.00062 20.1 12.3 3.1 3 0 0 3 3 3 2 EGF-like domain Bact_lectin PF18483.1 PRP82890.1 - 0.0054 16.8 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial lectin EGF_Tenascin PF18720.1 PRP82890.1 - 0.0084 16.1 8.7 0.0084 16.1 8.7 3.4 3 0 0 3 3 3 2 Tenascin EGF domain DUF4366 PF14283.6 PRP82890.1 - 0.056 13.5 0.5 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DUF5305 PF17231.2 PRP82890.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) hEGF PF12661.7 PRP82890.1 - 0.78 10.5 13.4 4 8.2 0.7 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF I-EGF_1 PF18372.1 PRP82890.1 - 2.3 8.4 10.3 1.7 8.8 5.0 2.8 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 IQ PF00612.27 PRP82891.1 - 0.00097 18.7 1.0 0.0024 17.5 1.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF5357 PF17310.2 PRP82891.1 - 5.7 5.4 7.1 13 4.2 7.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5357) PBD PF00786.28 PRP82892.1 - 8.5e-14 51.7 0.1 2.6e-13 50.1 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WH1 PF00568.23 PRP82892.1 - 7.5e-12 45.2 0.0 1.2e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 PRP82892.1 - 2.2e-06 27.3 0.1 3.9e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 WH2 motif SR-25 PF10500.9 PRP82892.1 - 0.00055 19.6 4.8 0.00085 19.0 4.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MTBP_C PF14920.6 PRP82892.1 - 0.0029 17.4 0.3 0.0045 16.8 0.3 1.2 1 0 0 1 1 1 1 MDM2-binding MID_MedPIWI PF18296.1 PRP82892.1 - 0.069 12.9 1.2 0.11 12.3 1.2 1.2 1 0 0 1 1 1 0 MID domain of medPIWI DUF3987 PF13148.6 PRP82892.1 - 0.44 9.5 4.7 0.76 8.7 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1682 PF07946.14 PRP82892.1 - 0.56 9.4 7.0 0.8 8.9 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NARP1 PF12569.8 PRP82892.1 - 1 8.2 6.1 1.4 7.7 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAP PF07174.11 PRP82892.1 - 1.1 8.7 27.6 1.5 8.3 23.5 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) PRCC PF10253.9 PRP82892.1 - 1.1 10.0 13.0 4.5 8.0 1.8 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Peptidase_S49_N PF08496.10 PRP82892.1 - 9.5 6.3 8.4 16 5.6 8.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RhoGEF PF00621.20 PRP82893.1 - 9.9e-42 143.2 1.4 1.5e-41 142.6 0.4 1.9 2 0 0 2 2 2 1 RhoGEF domain PB1 PF00564.24 PRP82893.1 - 0.02 14.8 0.1 0.062 13.2 0.1 1.9 1 0 0 1 1 1 0 PB1 domain Methyltransf_16 PF10294.9 PRP82895.1 - 8.6e-21 74.4 0.0 1.5e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 PRP82895.1 - 8.5e-07 28.9 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP82895.1 - 6.6e-05 23.5 0.0 0.00011 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP82895.1 - 0.0005 19.6 0.0 0.00063 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PRP82895.1 - 0.00055 19.5 0.1 0.0008 19.0 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Tox-ODYAM1 PF15642.6 PRP82895.1 - 0.0014 17.7 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus Cons_hypoth95 PF03602.15 PRP82895.1 - 0.0032 17.1 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 PRP82895.1 - 0.011 16.4 0.3 0.021 15.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 PRP82895.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PRP82895.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NNMT_PNMT_TEMT PF01234.17 PRP82895.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MethyltransfD12 PF02086.15 PRP82895.1 - 0.24 11.0 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase CH PF00307.31 PRP82897.1 - 6.2e-16 58.5 0.1 8.1e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain RPE65 PF03055.15 PRP82898.1 - 6.3e-112 375.1 0.3 9.4e-112 374.5 0.3 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pkinase_Tyr PF07714.17 PRP82898.1 - 2.7e-51 174.3 0.0 4.2e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82898.1 - 2.3e-48 164.9 0.0 3.9e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PH PF00169.29 PRP82898.1 - 4.9e-14 52.7 0.2 2.4e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 PH domain SH2 PF00017.24 PRP82898.1 - 1.1e-13 51.0 0.1 4.2e-13 49.2 0.0 2.1 2 0 0 2 2 1 1 SH2 domain PH_11 PF15413.6 PRP82898.1 - 0.0034 17.8 0.1 0.0097 16.3 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain SH2_2 PF14633.6 PRP82898.1 - 0.0095 15.4 0.0 0.03 13.7 0.0 1.7 2 0 0 2 2 2 1 SH2 domain Kdo PF06293.14 PRP82898.1 - 0.034 13.5 0.1 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP82898.1 - 0.096 11.4 0.0 0.41 9.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 PRP82898.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP82898.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 PRP82898.1 - 0.15 11.6 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL P21-Arc PF04062.14 PRP82899.1 - 1e-69 234.0 0.0 1.2e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit DUF2520 PF10728.9 PRP82899.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) His_Phos_2 PF00328.22 PRP82900.1 - 2.8e-14 53.3 0.1 3.8e-09 36.4 0.0 2.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Dioxygenase_C PF00775.21 PRP82902.1 - 1.1e-07 31.4 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Thioredoxin_8 PF13905.6 PRP82904.1 - 8.9e-24 83.7 0.0 1.6e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PRP82904.1 - 3.7e-08 33.3 0.0 1.2e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 PRP82904.1 - 4.9e-06 27.0 0.0 8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 PRP82904.1 - 0.0088 16.0 0.1 0.015 15.2 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PRP82904.1 - 0.016 14.9 0.0 3.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 PRP82904.1 - 0.034 14.4 0.3 6.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin Redoxin PF08534.10 PRP82904.1 - 0.055 13.2 0.1 0.19 11.4 0.1 1.8 1 1 0 1 1 1 0 Redoxin NADH_4Fe-4S PF10589.9 PRP82904.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Slx4 PF09494.10 PRP82905.1 - 0.17 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Slx4 endonuclease MoCF_biosynth PF00994.24 PRP82906.1 - 3e-57 192.3 0.0 1.7e-30 105.6 0.0 2.7 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.17 PRP82906.1 - 5.4e-39 133.5 0.8 1.1e-38 132.4 0.8 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 PRP82906.1 - 2.9e-13 49.8 0.0 7.6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) WD40 PF00400.32 PRP82906.1 - 6.2e-09 36.3 18.4 0.008 17.0 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_S6e PF01092.19 PRP82908.1 - 2.3e-57 192.4 0.1 2.3e-57 192.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Radical_SAM PF04055.21 PRP82909.1 - 4.3e-12 46.7 0.4 2.6e-10 40.9 0.0 2.3 1 1 1 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 PRP82909.1 - 0.00047 20.4 0.0 0.00083 19.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 PRP82909.1 - 0.058 13.5 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF4315 PF14193.6 PRP82909.1 - 0.11 12.5 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) Hydrolase PF00702.26 PRP82909.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sulfate_transp PF00916.20 PRP82911.1 - 1.1e-18 67.1 32.1 1.1e-18 67.1 32.1 2.4 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 PRP82911.1 - 7.4e-13 48.2 0.1 2.3e-12 46.6 0.1 1.9 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 PRP82911.1 - 3.2e-12 46.4 0.0 6.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EGF_2 PF07974.13 PRP82911.1 - 0.012 15.9 7.0 0.023 15.1 7.0 1.4 1 0 0 1 1 1 0 EGF-like domain Homeodomain PF00046.29 PRP82912.1 - 1.4e-15 56.8 5.0 2.8e-15 55.9 5.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP82912.1 - 1.7e-06 27.9 1.6 3.5e-06 26.8 1.3 1.8 1 1 0 1 1 1 1 Homeobox KN domain Pkinase_Tyr PF07714.17 PRP82913.1 - 7.7e-76 254.8 0.0 1.1e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82913.1 - 1.9e-45 155.3 0.0 2.7e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP82913.1 - 2.9e-30 103.8 79.8 9e-06 26.0 0.0 15.5 9 3 3 15 15 15 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP82913.1 - 9e-30 102.2 75.1 1.2e-06 28.2 0.2 12.8 6 1 6 14 14 14 13 Leucine rich repeat LRR_1 PF00560.33 PRP82913.1 - 2.1e-05 24.5 62.4 0.36 11.6 0.2 18.2 18 3 1 19 19 19 2 Leucine Rich Repeat Kinase-like PF14531.6 PRP82913.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP82913.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP82913.1 - 0.016 14.0 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 PRP82913.1 - 0.2 11.8 60.6 0.32 11.1 0.1 16.7 19 0 0 19 19 19 0 Leucine Rich repeat Pentapeptide PF00805.22 PRP82913.1 - 0.21 11.3 5.7 2.3 7.9 0.0 4.3 4 0 0 4 4 4 0 Pentapeptide repeats (8 copies) LRR_8 PF13855.6 PRP82914.1 - 3.1e-18 65.3 36.6 8.8e-05 22.2 1.5 6.2 5 2 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PRP82914.1 - 4.2e-17 62.0 47.0 4.2e-06 27.0 1.9 7.2 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP82914.1 - 1.9e-09 36.8 24.5 1.7 9.5 0.0 9.7 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP82914.1 - 0.005 16.8 38.6 3 8.1 0.3 9.0 9 0 0 9 9 9 4 Leucine Rich repeat Podoplanin PF05808.11 PRP82914.1 - 0.012 15.7 0.5 0.038 14.1 0.5 1.8 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 PRP82914.1 - 0.067 14.1 0.2 0.16 12.9 0.2 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CYYR1 PF10873.8 PRP82914.1 - 1.4 9.3 7.0 0.13 12.7 1.6 1.9 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 TFA2_Winged_2 PF18121.1 PRP82915.1 - 0.00015 21.4 0.2 0.0019 17.9 0.1 2.5 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 AGOG PF09171.10 PRP82915.1 - 0.011 15.1 0.1 0.014 14.7 0.1 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase ArgoN PF16486.5 PRP82915.1 - 0.046 14.3 2.7 0.28 11.8 2.7 2.1 1 1 0 1 1 1 0 N-terminal domain of argonaute ArlS_N PF18719.1 PRP82915.1 - 0.05 13.8 1.1 0.2 11.9 0.3 2.1 2 0 0 2 2 2 0 ArlS sensor domain Ribosomal_L22e PF01776.17 PRP82916.1 - 9.3e-50 167.6 1.7 1.2e-49 167.2 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3295 PF11702.8 PRP82916.1 - 0.027 13.8 0.2 0.031 13.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RPT PF13446.6 PRP82916.1 - 0.053 13.5 0.1 0.093 12.7 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein UPF0225 PF17775.1 PRP82916.1 - 0.12 13.2 1.3 0.3 11.9 0.6 1.8 2 0 0 2 2 2 0 UPF0225 domain Pkinase_Tyr PF07714.17 PRP82918.1 - 1e-30 106.9 0.0 1.7e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP82918.1 - 5.1e-20 71.9 0.0 8.6e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP82918.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CENP-B_dimeris PF09026.10 PRP82918.1 - 5.7 7.4 6.4 51 4.3 0.8 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain RNase_H2_suC PF08615.11 PRP82920.1 - 7.1e-08 32.7 1.2 0.0017 18.6 0.0 2.7 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) kleA_kleC PF17383.2 PRP82920.1 - 0.049 13.9 0.1 0.087 13.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Ammonium_transp PF00909.21 PRP82921.1 - 6.8e-49 166.6 28.3 9.4e-49 166.2 28.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family GLTP PF08718.11 PRP82923.1 - 1e-24 87.5 0.0 1.3e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Pkinase PF00069.25 PRP82924.1 - 1.8e-65 220.9 0.0 2.9e-65 220.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82924.1 - 1.7e-34 119.3 0.0 2.5e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PRP82924.1 - 4e-06 27.4 0.5 4e-06 27.4 0.5 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 PRP82924.1 - 5.6e-06 26.6 0.0 1.4e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 PRP82924.1 - 0.0008 18.8 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SGP PF17228.2 PRP82925.1 - 0.017 16.0 5.1 0.031 15.1 5.1 1.4 1 0 0 1 1 1 0 Sulphur globule protein Abhydrolase_1 PF00561.20 PRP82927.1 - 2.2e-05 24.3 0.0 4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP82927.1 - 3e-05 24.7 0.0 4.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP82927.1 - 0.031 13.5 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2207 PF09972.9 PRP82928.1 - 1.9 7.1 4.2 3 6.5 0.0 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 PRP82928.1 - 2.1 8.5 8.2 5.1 7.2 0.0 3.1 2 1 0 3 3 3 0 DHHC palmitoyltransferase Ank_2 PF12796.7 PRP82929.1 - 2.5e-22 79.3 0.0 3.5e-10 40.3 0.0 2.9 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP82929.1 - 5e-17 61.7 0.3 0.01 16.1 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP82929.1 - 2.9e-15 56.4 0.3 3.8e-05 24.1 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP82929.1 - 1.2e-13 49.9 0.8 0.53 11.0 0.0 6.7 6 1 1 7 7 7 4 Ankyrin repeat Ank PF00023.30 PRP82929.1 - 5e-13 48.9 1.2 0.24 11.9 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeat F-box-like PF12937.7 PRP82929.1 - 0.027 14.4 0.5 0.066 13.1 0.0 1.9 2 0 0 2 2 2 0 F-box-like VWA_3_C PF18571.1 PRP82929.1 - 0.1 12.5 0.0 6.1 6.8 0.0 3.7 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain SpoU_methylase PF00588.19 PRP82930.1 - 4.5e-30 104.7 0.0 1.4e-29 103.1 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 PRP82930.1 - 4.1e-17 62.2 0.1 1.5e-16 60.4 0.1 2.0 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding PELOTA_1 PF15608.6 PRP82930.1 - 0.012 15.5 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 PELOTA RNA binding domain DUF3474 PF11960.8 PRP82930.1 - 0.015 15.5 0.2 0.087 13.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) SH2 PF00017.24 PRP82931.1 - 2.9e-07 30.5 0.0 5.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 SH2 domain DUF4231 PF14015.6 PRP82931.1 - 0.055 14.0 0.4 1.8 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) G8 PF10162.9 PRP82932.1 - 5.6e-29 100.7 0.2 1.6e-28 99.2 0.2 1.9 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP82932.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 3.2 3 1 1 4 4 4 1 Right handed beta helix region Ribosomal_S18 PF01084.20 PRP82934.1 - 4.4e-09 36.4 0.1 9.9e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 IF-2B PF01008.17 PRP82934.1 - 0.025 13.8 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family RNA_polI_A34 PF08208.11 PRP82934.1 - 0.1 12.7 2.6 0.16 12.1 2.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Spexin PF15171.6 PRP82934.1 - 0.15 12.3 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin AAA_23 PF13476.6 PRP82934.1 - 0.5 10.8 3.7 1 9.9 3.7 1.4 1 0 0 1 1 1 0 AAA domain PrpF PF04303.13 PRP82936.1 - 2.1e-83 280.3 0.0 2.9e-83 279.9 0.0 1.1 1 0 0 1 1 1 1 PrpF protein zf-C3HC4_3 PF13920.6 PRP82936.1 - 6.6e-09 35.5 7.9 6.6e-09 35.5 7.9 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP82936.1 - 2.4e-05 24.1 9.3 2.4e-05 24.1 9.3 2.7 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP82936.1 - 0.011 15.7 8.0 0.011 15.7 8.0 3.3 3 1 1 4 4 4 0 zinc-RING finger domain Pkinase PF00069.25 PRP82937.1 - 1.1e-60 205.3 0.4 5.2e-33 114.5 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP82937.1 - 1e-30 106.9 0.0 5.7e-17 61.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase tRNA-synt_His PF13393.6 PRP82937.1 - 1.9e-23 83.2 1.8 2e-20 73.3 0.0 3.5 2 1 1 3 3 3 2 Histidyl-tRNA synthetase RWD PF05773.22 PRP82937.1 - 3.8e-17 62.6 0.0 1.4e-16 60.8 0.0 2.1 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.7 PRP82937.1 - 3e-13 49.9 0.1 3e-13 49.9 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.20 PRP82937.1 - 4e-07 30.1 2.3 4.2e-07 30.0 0.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain Kinase-like PF14531.6 PRP82937.1 - 0.023 14.0 0.0 0.091 12.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 PRP82937.1 - 0.082 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TP6A_N PF04406.14 PRP82938.1 - 1.7e-08 34.3 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 PRP82938.1 - 0.0025 17.7 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) DUF2220 PF09983.9 PRP82938.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Proteasome PF00227.26 PRP82939.1 - 1.8e-48 164.6 0.1 2.2e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 PRP82939.1 - 0.0044 16.4 1.1 0.0044 16.4 1.1 2.3 2 0 0 2 2 2 1 Proteasome beta subunits C terminal SNAP PF14938.6 PRP82940.1 - 4e-107 357.8 16.1 4.5e-107 357.7 16.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 PRP82940.1 - 2.2e-07 30.4 3.3 0.31 11.2 0.0 4.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PRP82940.1 - 1.5e-05 25.2 6.3 0.066 13.5 0.5 3.7 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 PRP82940.1 - 6.1e-05 23.4 7.7 0.3 11.8 0.1 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP82940.1 - 0.00035 20.5 12.5 0.03 14.4 0.5 5.1 3 2 4 7 7 7 1 Tetratricopeptide repeat DHR-2 PF06920.13 PRP82940.1 - 0.0021 16.8 3.2 0.043 12.5 1.6 2.6 1 1 1 3 3 3 2 Dock homology region 2 TPR_16 PF13432.6 PRP82940.1 - 0.0052 17.4 3.3 3.5 8.4 0.1 4.1 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP82940.1 - 0.0095 15.7 15.8 0.01 15.6 1.1 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP82940.1 - 0.013 16.2 0.6 21 6.2 0.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF410 PF04190.13 PRP82940.1 - 0.014 15.2 7.2 0.027 14.3 7.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF410) Spatacsin_C PF14649.6 PRP82940.1 - 0.037 13.1 6.9 0.049 12.7 0.3 2.7 2 1 0 3 3 3 0 Spatacsin C-terminus TPR_MalT PF17874.1 PRP82940.1 - 0.056 12.8 0.0 0.22 10.9 0.0 1.8 1 1 1 2 2 2 0 MalT-like TPR region TRAPPC-Trs85 PF12739.7 PRP82940.1 - 0.086 11.8 8.3 0.12 11.3 8.3 1.4 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit ANAPC3 PF12895.7 PRP82940.1 - 0.25 11.6 4.9 1.5 9.1 0.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NSF PF02071.20 PRP82940.1 - 1.1 10.3 17.6 14 7.0 0.1 7.2 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat MIT PF04212.18 PRP82940.1 - 2.2 8.4 12.0 5.3 7.2 0.5 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain F-box PF00646.33 PRP82941.1 - 0.0002 21.1 0.0 0.00051 19.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 PRP82941.1 - 0.0017 18.9 0.0 4.1 8.1 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP82941.1 - 0.0093 15.8 0.1 0.027 14.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Use1 PF09753.9 PRP82941.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ank_3 PF13606.6 PRP82941.1 - 0.093 13.3 0.0 5.9 7.8 0.0 3.8 4 1 1 5 5 5 0 Ankyrin repeat DUF3447 PF11929.8 PRP82941.1 - 0.11 12.4 0.1 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) Patched PF02460.18 PRP82942.1 - 1.9e-95 320.6 8.2 6.8e-95 318.9 8.2 1.7 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 PRP82942.1 - 3.3e-47 160.2 4.3 3.3e-47 160.2 4.3 3.7 3 1 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 PRP82942.1 - 1.2e-07 31.0 1.4 1.2e-07 31.0 1.4 2.3 2 0 0 2 2 2 1 MMPL family ACR_tran PF00873.19 PRP82942.1 - 0.00032 18.5 5.7 0.00032 18.5 5.7 1.7 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family Glyco_hydr_30_2 PF14587.6 PRP82944.1 - 5.6e-13 49.2 3.4 5.9e-13 49.1 1.4 1.9 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 EGF_2 PF07974.13 PRP82944.1 - 1.3 9.4 7.7 3 8.3 7.7 1.6 1 0 0 1 1 1 0 EGF-like domain WH2 PF02205.20 PRP82945.1 - 7.4e-09 35.2 0.8 4.1e-08 32.8 0.3 2.8 2 0 0 2 2 2 1 WH2 motif zinc_ribbon_15 PF17032.5 PRP82945.1 - 0.0015 19.2 2.1 0.0071 17.1 2.1 2.2 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 PRP82945.1 - 0.0039 17.2 1.8 0.0079 16.2 1.8 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 PRP82945.1 - 0.01 15.5 2.9 0.018 14.7 2.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 PRP82945.1 - 0.37 10.3 3.7 0.65 9.5 3.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.9 PRP82945.1 - 1 9.5 4.0 1.7 8.8 4.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 EB PF01683.18 PRP82946.1 - 0.007 16.6 1.1 0.012 15.9 1.1 1.3 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 PRP82946.1 - 0.0099 16.2 7.7 0.017 15.5 7.7 1.4 1 0 0 1 1 1 1 EGF-like domain YbfN PF13982.6 PRP82946.1 - 0.032 14.5 0.4 0.3 11.4 0.2 2.1 2 0 0 2 2 2 0 YbfN-like lipoprotein APG6_N PF17675.1 PRP82946.1 - 5.2 7.6 11.7 0.83 10.2 7.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Nicastrin PF05450.15 PRP82947.1 - 4.3e-41 140.9 0.3 7e-41 140.2 0.3 1.3 1 0 0 1 1 1 1 Nicastrin Ncstrn_small PF18266.1 PRP82947.1 - 2e-32 112.5 0.1 4.8e-32 111.3 0.0 1.7 2 0 0 2 2 2 1 Nicastrin small lobe Peptidase_M28 PF04389.17 PRP82947.1 - 5.5e-10 39.3 0.6 1.1e-09 38.3 0.6 1.5 1 1 0 1 1 1 1 Peptidase family M28 EB PF01683.18 PRP82947.1 - 0.24 11.7 1.7 1.5 9.1 0.7 2.4 2 0 0 2 2 2 0 EB module Lyase_aromatic PF00221.19 PRP82948.1 - 2.2e-187 623.4 0.0 1e-186 621.2 0.0 1.8 1 1 0 1 1 1 1 Aromatic amino acid lyase Coatomer_E PF04733.14 PRP82950.1 - 1.6e-84 283.8 2.4 1.8e-84 283.6 2.4 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 PRP82950.1 - 6.4e-11 41.5 2.0 1.6e-05 24.7 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP82950.1 - 1.7e-10 40.3 0.4 4.7e-06 26.2 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP82950.1 - 1.2e-08 35.5 0.7 8.6e-05 23.1 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 PRP82950.1 - 3.5e-08 33.3 0.2 0.017 15.4 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP82950.1 - 1.5e-07 31.8 10.0 0.00013 22.4 0.0 4.0 4 1 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP82950.1 - 3.4e-07 30.5 2.4 0.045 14.6 0.1 4.8 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP82950.1 - 5.8e-06 26.5 2.8 0.0017 18.6 0.1 3.9 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP82950.1 - 2.2e-05 24.3 0.6 0.15 12.3 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP82950.1 - 0.00043 20.1 3.3 0.069 13.2 0.0 4.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 PRP82950.1 - 0.00081 18.7 2.0 0.0075 15.5 0.1 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP82950.1 - 0.001 18.9 1.6 0.02 14.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP82950.1 - 0.0039 17.4 0.8 0.2 11.9 0.1 2.8 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PRP82950.1 - 0.0063 16.2 1.1 0.41 10.4 0.0 4.0 4 1 1 5 5 5 1 TPR repeat RPN7 PF10602.9 PRP82950.1 - 0.073 12.8 0.0 0.3 10.8 0.0 2.1 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 PRP82950.1 - 0.19 11.4 3.0 0.31 10.7 1.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TMEM138 PF14935.6 PRP82951.1 - 1.2e-12 48.6 12.8 1.8e-12 48.0 12.8 1.3 1 0 0 1 1 1 1 Transmembrane protein 138 DUF2070 PF09843.9 PRP82951.1 - 0.95 7.7 11.4 1.2 7.4 11.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LRR_4 PF12799.7 PRP82952.1 - 1.7e-15 56.9 15.0 7.6e-06 26.2 0.5 4.6 2 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP82952.1 - 2.9e-09 36.7 4.6 7.1e-06 25.6 0.5 2.9 1 1 2 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 PRP82952.1 - 4.1e-07 29.7 12.4 0.0001 22.0 3.4 4.2 2 2 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 PRP82952.1 - 9.9e-05 22.1 11.4 1.9 8.8 0.2 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 PRP82952.1 - 0.0045 17.4 8.2 10 7.2 0.0 5.9 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_2 PF07723.13 PRP82952.1 - 0.011 16.4 0.3 1.6 9.5 0.0 3.3 4 0 0 4 4 4 0 Leucine Rich Repeat HA PF03457.14 PRP82953.1 - 5.3e-20 71.5 14.4 1.8e-08 34.6 0.0 4.3 4 0 0 4 4 4 3 Helicase associated domain CI-B14_5a PF07347.12 PRP82953.1 - 0.022 14.6 0.1 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Autophagy_N PF03986.13 PRP82954.1 - 2.9e-32 111.5 0.1 4.5e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 PRP82954.1 - 6.8e-20 71.4 1.5 1.2e-19 70.6 0.9 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 PRP82954.1 - 1e-08 34.6 0.0 2.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal PHD PF00628.29 PRP82955.1 - 6.7e-05 22.7 6.5 0.00014 21.6 6.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 PRP82955.1 - 0.0039 17.3 0.8 0.01 16.0 0.8 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PRP82955.1 - 0.077 13.3 3.7 0.25 11.6 3.7 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 PRP82955.1 - 0.13 12.1 2.6 0.33 10.9 2.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_3 PF13922.6 PRP82955.1 - 0.16 12.3 1.1 0.46 10.9 1.1 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx C1_2 PF03107.16 PRP82955.1 - 0.3 11.4 6.7 0.19 12.1 3.4 2.4 2 0 0 2 2 2 0 C1 domain Rap_GAP PF02145.15 PRP82956.1 - 2.8e-17 62.9 0.0 5.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP PglZ PF08665.12 PRP82956.1 - 0.0099 16.0 0.1 0.2 11.8 0.0 2.9 3 0 0 3 3 3 1 PglZ domain tRNA-synt_1g PF09334.11 PRP82957.1 - 2.3e-89 299.9 0.0 1.1e-48 165.9 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA_bind PF01588.20 PRP82957.1 - 2.9e-28 97.8 0.6 6.4e-28 96.7 0.6 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 PRP82957.1 - 8.9e-26 90.3 0.7 7.5e-13 47.6 0.0 4.2 1 1 3 4 4 4 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PRP82957.1 - 9.3e-10 38.7 0.0 1.9e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PRP82957.1 - 1.2e-09 37.9 0.0 6.1e-06 25.8 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain FH2 PF02181.23 PRP82958.1 - 1.3e-85 287.8 0.1 1.3e-85 287.8 0.1 3.5 5 0 0 5 5 5 1 Formin Homology 2 Domain Drf_GBD PF06371.13 PRP82958.1 - 7.4e-30 103.9 0.2 7.4e-30 103.9 0.2 3.9 5 0 0 5 5 5 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PRP82958.1 - 1.5e-20 73.6 1.0 1.5e-20 73.6 1.0 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain Phycobilisome PF00502.19 PRP82958.1 - 0.056 13.4 0.3 0.056 13.4 0.3 2.3 3 0 0 3 3 3 0 Phycobilisome protein Baculo_PEP_C PF04513.12 PRP82958.1 - 3.9 7.5 6.8 1.6 8.7 0.0 3.5 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 PRP82958.1 - 7.1 5.9 41.1 0.054 12.8 0.8 4.2 3 1 0 4 4 4 0 Domain of unknown function (DUF4407) HSP33 PF01430.19 PRP82959.1 - 2.8e-42 145.0 1.7 4e-42 144.5 1.7 1.2 1 0 0 1 1 1 1 Hsp33 protein Med1 PF10744.9 PRP82959.1 - 0.0039 16.3 0.1 0.0078 15.3 0.0 1.5 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Strep_his_triad PF04270.13 PRP82959.1 - 0.03 14.3 0.4 0.069 13.2 0.1 1.8 2 0 0 2 2 2 0 Streptococcal histidine triad protein LRR_9 PF14580.6 PRP82960.1 - 3.6e-09 36.3 1.8 6.8e-06 25.7 1.8 2.3 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 PRP82960.1 - 1.1e-06 28.3 18.9 1.9e-05 24.4 4.7 3.3 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 PRP82960.1 - 4e-06 27.1 18.4 0.0048 17.3 0.1 4.5 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) ANAPC4_WD40 PF12894.7 PRP82960.1 - 4.5e-06 26.9 0.0 0.56 10.6 0.0 4.1 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP82960.1 - 2.2e-05 25.1 2.8 0.03 15.2 0.1 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Cu_bind_like PF02298.17 PRP82960.1 - 0.074 13.1 0.1 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Plastocyanin-like domain SET PF00856.28 PRP82961.1 - 2.5e-09 37.7 0.1 4.7e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 PRP82961.1 - 9.1e-06 25.7 12.5 9.1e-06 25.7 12.5 3.2 2 1 1 3 3 3 1 MYND finger DUF913 PF06025.12 PRP82961.1 - 0.051 12.6 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NAD_binding_10 PF13460.6 PRP82962.1 - 4.5e-09 36.5 0.0 5.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 PRP82962.1 - 0.0001 22.7 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 PRP82962.1 - 0.00069 19.2 0.0 0.00089 18.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PRP82962.1 - 0.0027 17.3 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 PRP82962.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 PRP82962.1 - 0.087 13.1 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Coilin_N PF15862.5 PRP82964.1 - 5.4e-09 36.0 17.1 5.4e-09 36.0 17.1 3.7 2 1 1 3 3 3 1 Coilin N-terminus Asp-B-Hydro_N PF05279.11 PRP82964.1 - 0.057 13.5 39.4 0.094 12.8 39.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.11 PRP82964.1 - 0.64 8.4 42.5 0.77 8.2 42.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Mitofilin PF09731.9 PRP82964.1 - 0.7 8.7 40.9 0.97 8.2 40.9 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PRKCSH PF07915.13 PRP82965.1 - 9e-13 49.0 1.3 2.1e-12 47.9 1.3 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 PRP82965.1 - 1.6e-07 31.1 0.3 2.6e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRIMA1 PF16101.5 PRP82966.1 - 0.00093 19.2 0.3 0.0017 18.4 0.3 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Fascin PF06268.13 PRP82967.1 - 4e-09 36.7 0.0 1.5e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 Fascin domain bZIP_2 PF07716.15 PRP82967.1 - 0.012 15.7 12.3 0.061 13.4 12.3 2.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 PRP82967.1 - 0.085 13.0 11.4 0.29 11.3 11.4 2.0 1 0 0 1 1 1 0 bZIP transcription factor NusG_add PF18298.1 PRP82967.1 - 0.16 12.2 2.4 0.57 10.4 0.1 2.4 2 0 0 2 2 2 0 NusG additional domain TFIIA PF03153.13 PRP82967.1 - 2.5 8.0 26.3 0.043 13.8 17.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SGP PF17228.2 PRP82967.1 - 4.9 8.1 12.8 12 6.8 12.8 1.6 1 0 0 1 1 1 0 Sulphur globule protein Neur_chan_memb PF02932.16 PRP82967.1 - 7.8 6.5 7.3 23 4.9 7.3 1.9 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med1 PF10744.9 PRP82968.1 - 1.3e-13 50.9 11.7 1.3e-13 50.9 11.7 2.2 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 NYD-SP28_assoc PF14775.6 PRP82968.1 - 0.16 12.1 3.9 0.14 12.2 1.0 2.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Ribosomal_S13 PF00416.22 PRP82968.1 - 5.3 7.4 9.1 2.6 8.4 2.9 3.2 3 1 0 3 3 3 0 Ribosomal protein S13/S18 IBR PF01485.21 PRP82970.1 - 0.87 9.9 13.9 3.2 8.0 13.9 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-B_box PF00643.24 PRP82970.1 - 1.4 9.1 10.7 0.66 10.2 6.0 2.1 2 0 0 2 2 2 0 B-box zinc finger zf-piccolo PF05715.13 PRP82970.1 - 6.6 7.0 14.9 1.5e+02 2.6 14.9 2.4 1 1 0 1 1 1 0 Piccolo Zn-finger Med18 PF09637.10 PRP82971.1 - 3e-10 40.4 0.0 3.5e-08 33.6 0.0 2.1 1 1 1 2 2 2 2 Med18 protein EF-hand_7 PF13499.6 PRP82972.1 - 4.2e-07 30.3 0.2 3.3e-05 24.3 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP82972.1 - 7.6e-06 25.1 0.4 0.19 11.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PRP82972.1 - 6.7e-05 22.5 0.1 0.061 13.3 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 PRP82972.1 - 0.001 18.9 0.9 0.22 11.4 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 PRP82972.1 - 0.067 13.5 0.0 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Branch PF02485.21 PRP82974.1 - 2.3e-22 79.7 0.1 3.3e-22 79.2 0.1 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme CAP59_mtransfer PF11735.8 PRP82976.1 - 1.2e-52 179.0 0.0 2.3e-52 178.1 0.0 1.5 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CotH PF08757.11 PRP82976.1 - 4.8e-25 88.8 3.6 2.3e-23 83.3 3.6 2.3 1 1 0 1 1 1 1 CotH kinase protein Aminotran_1_2 PF00155.21 PRP82976.1 - 1.9e-21 76.6 0.0 2.8e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II EGF PF00008.27 PRP82976.1 - 0.00059 20.1 7.0 0.00059 20.1 7.0 2.8 2 1 0 2 2 2 1 EGF-like domain EGF_2 PF07974.13 PRP82976.1 - 0.2 12.0 33.6 0.37 11.2 9.8 3.1 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 PRP82976.1 - 2 9.2 18.1 0.054 14.1 7.6 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF DNA_pol_B PF00136.21 PRP82977.1 - 1.6e-148 495.3 0.1 2.2e-148 494.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PRP82977.1 - 3.2e-79 266.5 0.1 5.6e-79 265.7 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PRP82977.1 - 4.6e-19 68.6 7.4 1e-18 67.5 7.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 PRP82977.1 - 0.00033 20.7 0.1 0.0016 18.4 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 PRP82977.1 - 0.0022 16.9 0.4 0.0037 16.2 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 PRP82977.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 PRP82977.1 - 3.9 7.4 5.0 14 5.6 5.0 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) adh_short_C2 PF13561.6 PRP82978.1 - 1.4e-59 201.5 0.0 4.1e-59 200.0 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP82978.1 - 6.6e-45 153.0 0.4 1.2e-44 152.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 PRP82978.1 - 1.3e-08 34.9 0.0 2.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PRP82978.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DICT PF10069.9 PRP82978.1 - 0.021 14.6 0.0 3.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system NUDIX PF00293.28 PRP82979.1 - 1.7e-15 57.3 0.2 1.3e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain PQ-loop PF04193.14 PRP82980.1 - 8.9e-11 41.4 9.1 1.4e-07 31.2 2.6 2.9 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 PRP82980.1 - 6.4 6.9 10.4 0.19 11.8 1.8 2.7 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange z-alpha PF02295.17 PRP82982.1 - 0.029 14.4 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain TFIIE_beta PF02186.15 PRP82982.1 - 0.067 13.5 0.3 2.9 8.2 0.0 3.0 2 1 1 3 3 3 0 TFIIE beta subunit core domain Lant_dehydr_N PF04738.13 PRP82982.1 - 0.1 10.7 0.0 2.5 6.1 0.0 2.0 2 0 0 2 2 2 0 Lantibiotic dehydratase, N terminus HalX PF08663.10 PRP82984.1 - 0.024 15.0 0.2 0.027 14.8 0.2 1.1 1 0 0 1 1 1 0 HalX domain PI3_PI4_kinase PF00454.27 PRP82985.1 - 5.5e-32 111.5 0.4 2.4e-22 79.9 0.7 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PRP82985.1 - 0.0028 17.1 0.2 0.0055 16.1 0.0 1.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 PRP82985.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RRS1 PF04939.12 PRP82986.1 - 1.2e-49 168.3 2.8 1.2e-49 168.3 2.8 2.0 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) SnAC PF14619.6 PRP82986.1 - 3.9 8.2 8.3 2.2 8.9 2.0 2.7 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex SF1-HH PF16275.5 PRP82987.1 - 3.6e-34 117.5 1.2 6.3e-34 116.7 1.2 1.4 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 PRP82987.1 - 1.2e-08 34.7 0.1 2.2e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 KH domain Pkinase PF00069.25 PRP82988.1 - 6.4e-48 163.4 0.0 9.6e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pro-kuma_activ PF09286.11 PRP82988.1 - 2.9e-22 79.5 0.1 7.1e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Pkinase_Tyr PF07714.17 PRP82988.1 - 1.4e-17 63.9 0.0 2.2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_S8 PF00082.22 PRP82988.1 - 2.7e-08 33.4 2.7 4.6e-08 32.7 2.7 1.3 1 0 0 1 1 1 1 Subtilase family Choline_kinase PF01633.20 PRP82988.1 - 0.012 15.2 0.1 0.089 12.4 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 PRP82988.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ACT_7 PF13840.6 PRP82990.1 - 1.4e-25 88.9 0.5 4.2e-13 48.9 0.0 3.0 3 0 0 3 3 3 2 ACT domain Castor1_N PF18700.1 PRP82990.1 - 3e-07 30.1 0.4 0.019 14.8 0.0 2.4 2 0 0 2 2 2 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain PH PF00169.29 PRP82991.1 - 4.8e-50 168.5 16.6 6.7e-12 45.9 0.2 6.6 6 0 0 6 6 6 6 PH domain RhoGAP PF00620.27 PRP82991.1 - 4.7e-31 107.7 0.0 9e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH_8 PF15409.6 PRP82991.1 - 1.4e-15 57.3 12.3 0.016 15.5 0.0 6.4 6 0 0 6 6 6 4 Pleckstrin homology domain PH_9 PF15410.6 PRP82991.1 - 1.1e-06 29.0 3.8 0.014 15.8 0.0 4.9 5 0 0 5 5 4 1 Pleckstrin homology domain PH_3 PF14593.6 PRP82991.1 - 1.9e-06 27.9 8.1 0.032 14.3 0.1 5.2 4 1 1 5 5 5 2 PH domain PH_16 PF17838.1 PRP82991.1 - 3.5e-06 26.9 0.7 0.29 11.0 0.0 4.8 6 0 0 6 6 6 2 PH domain PH_11 PF15413.6 PRP82991.1 - 2.9e-05 24.4 35.6 4.5 7.8 0.1 10.1 7 5 2 9 9 9 4 Pleckstrin homology domain PH_13 PF16652.5 PRP82991.1 - 0.00025 20.9 3.3 1.7 8.5 0.0 4.3 4 0 0 4 4 4 2 Pleckstrin homology domain PH_17 PF18012.1 PRP82991.1 - 0.0016 18.2 0.4 1.5 8.6 0.0 4.4 4 0 0 4 4 4 1 PH domain zf-RING_12 PF17976.1 PRP82991.1 - 0.13 12.6 0.1 3.5 8.0 0.0 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SoxD PF04267.12 PRP82991.1 - 1.2 9.2 4.3 9.2 6.5 0.3 3.8 4 0 0 4 4 4 0 Sarcosine oxidase, delta subunit family Peptidase_S8 PF00082.22 PRP82992.1 - 3.6e-39 134.8 2.8 5.1e-39 134.3 2.8 1.2 1 0 0 1 1 1 1 Subtilase family EGF_2 PF07974.13 PRP82992.1 - 0.01 16.2 34.0 0.048 14.0 15.1 2.3 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 PRP82992.1 - 4.6 8.0 17.0 1.1 9.9 2.1 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF Peptidase_S10 PF00450.22 PRP82994.1 - 9.4e-111 371.2 0.1 1.3e-110 370.7 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase NifU PF01106.17 PRP82995.1 - 8.8e-28 96.3 0.0 1.3e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 PRP82995.1 - 1.5e-26 92.2 0.0 3.2e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal SH3_2 PF07653.17 PRP82996.1 - 3.6e-07 29.8 0.0 6.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PRP82996.1 - 3.4e-06 26.8 0.0 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP82996.1 - 0.021 14.4 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Band_7 PF01145.25 PRP82998.1 - 1.9e-16 60.6 0.1 1.9e-16 60.6 0.1 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family CH PF00307.31 PRP82999.1 - 8.6e-32 109.6 0.3 7.1e-16 58.3 0.2 3.7 4 0 0 4 4 4 2 Calponin homology (CH) domain ANAPC4_WD40 PF12894.7 PRP82999.1 - 7.9e-09 35.7 2.9 0.031 14.6 0.0 5.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP82999.1 - 8.8e-07 29.5 13.1 0.054 14.4 0.0 7.1 8 0 0 8 8 8 2 WD domain, G-beta repeat PD40 PF07676.12 PRP82999.1 - 0.0044 16.9 0.1 0.16 12.0 0.0 3.5 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 PRP82999.1 - 0.083 13.4 1.2 39 4.9 0.0 4.6 5 0 0 5 5 5 0 PQQ-like domain Ge1_WD40 PF16529.5 PRP82999.1 - 0.14 11.1 0.0 13 4.6 0.0 3.6 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NUP214 PF16755.5 PRP82999.1 - 0.16 11.2 2.3 0.16 11.2 0.4 1.8 2 0 0 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PI3K_1B_p101 PF10486.9 PRP83000.1 - 0.43 8.3 19.8 0.51 8.0 19.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Baculo_F PF12259.8 PRP83000.1 - 4.3 5.7 11.7 5 5.5 11.7 1.0 1 0 0 1 1 1 0 Baculovirus F protein Synaptobrevin PF00957.21 PRP83000.1 - 7.6 6.4 9.6 11 5.8 4.5 2.3 1 1 1 2 2 2 0 Synaptobrevin adh_short PF00106.25 PRP83001.1 - 5.3e-37 127.2 0.0 7.9e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP83001.1 - 1.1e-29 103.7 0.0 3.5e-29 102.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP83001.1 - 4.1e-09 36.6 0.5 7.7e-09 35.7 0.5 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 PRP83001.1 - 0.0075 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Colicin_im PF03857.13 PRP83001.1 - 2.3 8.2 7.6 0.12 12.4 1.1 2.1 2 0 0 2 2 2 0 Colicin immunity protein S8_pro-domain PF16470.5 PRP83004.1 - 1.5e-12 48.1 0.0 2.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase S8 pro-domain DUF4606 PF15379.6 PRP83004.1 - 0.13 12.5 0.1 0.24 11.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) TIG PF01833.24 PRP83005.1 - 4e-06 26.8 0.0 9.3e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain DUF3563 PF12086.8 PRP83005.1 - 0.095 12.4 2.0 0.15 11.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) SET PF00856.28 PRP83006.1 - 1.7e-11 44.8 0.0 3.9e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 PRP83006.1 - 0.0015 19.2 1.0 0.0026 18.4 0.4 1.7 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Spore_III_AB PF09548.10 PRP83006.1 - 0.058 13.5 0.3 14 5.8 0.5 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Ras PF00071.22 PRP83007.1 - 1.1e-49 168.2 0.0 1.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP83007.1 - 1.2e-23 83.6 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP83007.1 - 4.3e-07 29.6 0.0 5.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP83007.1 - 0.03 13.8 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP83007.1 - 0.048 13.8 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP83007.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Arf PF00025.21 PRP83008.1 - 2.7e-11 43.2 0.0 2.8e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PRP83008.1 - 0.077 12.6 0.0 0.084 12.5 0.0 1.0 1 0 0 1 1 1 0 Ras family Folliculin PF11704.8 PRP83010.1 - 0.022 14.6 0.2 0.071 13.0 0.0 1.9 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport SSXT PF05030.12 PRP83011.1 - 0.0061 16.2 0.1 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 SSXT protein (N-terminal region) GST_C_3 PF14497.6 PRP83011.1 - 0.0069 16.6 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain G-patch PF01585.23 PRP83015.1 - 7.2e-11 41.8 2.3 1.3e-10 40.9 2.3 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 PRP83015.1 - 1.2e-05 25.4 5.6 2.2e-05 24.6 5.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 PRP83015.1 - 0.0041 17.2 0.7 0.011 15.8 0.7 1.7 1 0 0 1 1 1 1 G-patch domain zf-C2H2_2 PF12756.7 PRP83015.1 - 0.0097 16.2 3.7 0.017 15.4 3.7 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 PRP83015.1 - 0.01 16.6 0.6 0.021 15.6 0.6 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 PRP83015.1 - 0.012 15.9 1.1 0.028 14.8 1.1 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 PRP83015.1 - 0.026 15.0 1.2 0.045 14.2 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type AAA_13 PF13166.6 PRP83015.1 - 0.031 13.0 1.5 0.044 12.4 1.5 1.1 1 0 0 1 1 1 0 AAA domain CYYR1 PF10873.8 PRP83015.1 - 7.1 7.1 6.4 11 6.4 6.4 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Metallophos PF00149.28 PRP83017.1 - 7.5e-18 65.8 0.1 1.1e-17 65.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PRP83017.1 - 1.6e-11 44.6 1.8 2.4e-11 44.0 0.2 2.1 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain fn3_PAP PF17808.1 PRP83017.1 - 5.5e-09 36.2 1.7 2.8e-07 30.7 0.6 3.2 2 1 0 2 2 2 1 Fn3-like domain from Purple Acid Phosphatase Metallophos_C PF14008.6 PRP83017.1 - 0.0015 19.4 0.3 0.0049 17.7 0.3 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 PRP83017.1 - 0.0043 17.3 0.0 0.01 16.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA-synt_1 PF00133.22 PRP83020.1 - 2.8e-43 148.1 0.0 8.8e-20 70.5 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PRP83020.1 - 1.8e-19 69.8 0.0 2.3e-10 39.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PRP83020.1 - 6.9e-14 52.1 0.0 1.3e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PRP83020.1 - 6.5e-05 22.4 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Tropomodulin PF03250.14 PRP83020.1 - 0.027 14.5 0.2 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 Tropomodulin RicinB_lectin_2 PF14200.6 PRP83021.1 - 5.5e-13 49.4 6.4 5.6e-11 43.0 0.2 3.8 3 1 2 5 5 5 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 PRP83021.1 - 7.1e-06 26.3 1.3 2.3e-05 24.6 0.0 2.2 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain BES1_N PF05687.13 PRP83021.1 - 1.1 9.6 8.1 3.9 7.8 8.1 2.1 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal VWA_N2 PF16164.5 PRP83021.1 - 1.9 8.7 0.0 1.9 8.7 0.0 2.9 2 1 0 2 2 2 0 VWA N-terminal Mucin PF01456.17 PRP83021.1 - 4.5 7.3 31.7 11 6.0 31.7 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Thaumatin PF00314.17 PRP83023.1 - 3.6e-08 33.3 6.5 1.2e-05 25.0 1.1 3.1 3 1 0 3 3 3 2 Thaumatin family Carb_bind PF10645.9 PRP83023.1 - 0.0022 18.2 2.9 0.0087 16.3 2.9 2.1 1 0 0 1 1 1 1 Carbohydrate binding Maf1 PF09174.10 PRP83024.1 - 1.1e-54 185.3 0.1 2.4e-54 184.1 0.1 1.6 1 0 0 1 1 1 1 Maf1 regulator Clathrin PF00637.20 PRP83024.1 - 2.5e-22 79.3 4.0 6.8e-22 77.9 1.6 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 PRP83024.1 - 0.00048 20.5 0.2 0.00048 20.5 0.2 2.4 4 0 0 4 4 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 PRP83024.1 - 0.0024 17.6 4.2 0.0033 17.2 1.1 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 PRP83024.1 - 0.0095 15.9 0.9 0.0095 15.9 0.9 2.1 2 1 0 2 2 2 1 zinc-RING finger domain Vps39_1 PF10366.9 PRP83024.1 - 0.0096 16.2 1.1 0.23 11.8 0.2 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.32 PRP83024.1 - 0.018 15.9 0.3 0.13 13.2 0.0 2.7 2 0 0 2 2 1 0 WD domain, G-beta repeat zf-C3H2C3 PF17122.5 PRP83024.1 - 0.023 14.8 0.1 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger WD40_like PF17005.5 PRP83024.1 - 0.042 13.2 0.1 0.47 9.7 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain ANAPC4_WD40 PF12894.7 PRP83024.1 - 0.12 12.7 0.0 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 PRP83024.1 - 0.12 12.7 9.7 0.093 13.1 4.7 3.2 3 1 1 4 4 4 0 Ring finger domain zf-C3HC4_3 PF13920.6 PRP83024.1 - 0.15 11.9 3.5 0.37 10.7 0.4 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 PRP83024.1 - 0.52 10.3 5.8 0.086 12.8 1.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 PRP83024.1 - 0.65 9.7 4.2 0.6 9.8 0.7 2.7 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 PRP83024.1 - 1 9.7 3.2 1.2 9.5 0.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain ZZ PF00569.17 PRP83025.1 - 2.3e-13 49.7 8.2 4.7e-13 48.7 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 PRP83025.1 - 0.097 13.0 10.9 0.42 11.0 8.7 2.3 2 0 0 2 2 2 0 C1 domain Pkinase_Tyr PF07714.17 PRP83026.1 - 1.5e-46 158.8 0.0 1.9e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83026.1 - 5.4e-45 153.8 0.0 6.8e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP83026.1 - 6.4e-05 23.0 0.0 0.0047 16.9 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP83026.1 - 0.0046 15.8 0.0 0.0065 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP83026.1 - 0.27 10.1 0.0 4.9 6.0 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain FAD_binding_3 PF01494.19 PRP83027.1 - 4.6e-60 203.7 0.0 6.4e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 PRP83027.1 - 7.9e-10 38.8 0.0 3.4e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PRP83027.1 - 4.2e-06 26.1 0.0 0.00018 20.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PRP83027.1 - 6.7e-06 25.5 0.7 0.011 15.0 0.1 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP83027.1 - 5.7e-05 22.5 1.8 0.0035 16.6 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP83027.1 - 0.00011 21.1 1.4 0.029 13.1 0.3 2.2 2 0 0 2 2 2 2 HI0933-like protein SE PF08491.10 PRP83027.1 - 0.0002 20.5 0.0 0.0015 17.7 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.17 PRP83027.1 - 0.00031 20.1 0.3 0.00074 18.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 PRP83027.1 - 0.00036 20.7 0.2 0.001 19.2 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PRP83027.1 - 0.00076 20.0 0.2 2 9.0 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP83027.1 - 0.00077 18.6 0.5 0.0013 17.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PRP83027.1 - 0.0016 17.8 0.8 0.013 14.9 0.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 PRP83027.1 - 0.0021 17.0 1.1 1.1 8.0 0.0 2.8 2 1 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.24 PRP83027.1 - 0.004 16.5 0.0 0.1 11.8 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DUF5326 PF17260.2 PRP83027.1 - 6 7.1 7.8 11 6.2 7.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) PAC2 PF09754.9 PRP83028.1 - 5.5e-12 46.1 0.0 2.1e-09 37.7 0.0 2.1 1 1 0 2 2 2 2 PAC2 family CX9C PF16860.5 PRP83029.1 - 7e-05 22.8 7.2 0.00054 19.9 0.8 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 PRP83029.1 - 0.0011 19.0 0.3 0.0011 19.0 0.3 2.3 3 0 0 3 3 3 1 CHCH domain MTCP1 PF08991.10 PRP83029.1 - 0.0038 17.4 1.0 0.0038 17.4 1.0 1.9 1 1 1 2 2 2 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 PRP83029.1 - 0.35 11.2 8.2 0.79 10.1 2.8 2.9 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 SGP PF17228.2 PRP83031.1 - 7 7.6 30.2 3.6 8.5 15.6 2.5 1 1 1 2 2 2 0 Sulphur globule protein Ank_2 PF12796.7 PRP83032.1 - 2.8e-34 117.6 7.5 2.2e-09 37.8 0.0 6.6 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP83032.1 - 6.9e-31 106.2 10.7 1.5e-07 31.8 0.0 8.3 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP83032.1 - 5.3e-30 103.1 9.4 5.4e-06 26.6 0.1 8.0 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP83032.1 - 7.8e-28 95.7 10.3 0.015 15.7 0.2 9.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 PRP83032.1 - 3.3e-24 82.3 12.3 0.008 16.6 0.0 8.9 10 0 0 10 10 10 6 Ankyrin repeat H2TH PF06831.14 PRP83032.1 - 1.5e-17 63.3 0.0 3.3e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain T7SS_ESX_EspC PF10824.8 PRP83033.1 - 0.16 12.4 0.0 0.16 12.4 0.0 8.1 8 2 1 10 10 10 0 Excreted virulence factor EspC, type VII ESX diderm UXS1_N PF11803.8 PRP83033.1 - 1.3 9.4 3.7 1.9 8.9 0.0 3.3 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal Mtc PF03820.17 PRP83034.1 - 4.6e-116 387.2 0.4 5.3e-116 387.0 0.4 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier FGGY_C PF02782.16 PRP83034.1 - 0.026 14.3 0.0 0.057 13.1 0.0 1.4 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain UPF0014 PF03649.13 PRP83034.1 - 0.089 12.1 2.3 4.5 6.5 0.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0014) FHA PF00498.26 PRP83035.1 - 4.5e-09 36.5 0.2 1e-08 35.4 0.2 1.6 1 0 0 1 1 1 1 FHA domain zf-C3HC4_3 PF13920.6 PRP83035.1 - 1.1e-08 34.8 8.7 1.1e-08 34.8 8.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP83035.1 - 2.6e-08 33.6 12.1 5.8e-08 32.4 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP83035.1 - 3.1e-07 30.6 10.7 3.1e-07 30.6 10.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PRP83035.1 - 8.2e-07 28.8 12.1 8.2e-07 28.8 12.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP83035.1 - 3.8e-06 27.1 7.5 1.2e-05 25.5 6.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain Yop-YscD_cpl PF16697.5 PRP83035.1 - 3e-05 24.3 1.1 0.00014 22.1 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_UBOX PF13445.6 PRP83035.1 - 6.8e-05 22.8 10.0 0.0001 22.3 7.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PRP83035.1 - 8.8e-05 22.6 11.4 0.00023 21.3 11.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PRP83035.1 - 0.00025 20.8 7.5 0.00025 20.8 7.5 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP83035.1 - 0.00034 20.5 10.2 0.0018 18.2 10.2 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 PRP83035.1 - 0.0037 17.4 7.1 0.0078 16.3 7.1 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 PRP83035.1 - 0.041 14.1 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 U-box domain FtsK_SpoIIIE_N PF12538.8 PRP83035.1 - 0.086 13.1 0.0 0.086 13.1 0.0 2.4 3 0 0 3 3 3 0 DNA transporter zf-RING_4 PF14570.6 PRP83035.1 - 0.14 12.0 6.1 0.038 13.8 2.8 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain YadA_stalk PF05662.14 PRP83035.1 - 0.14 12.5 0.3 0.32 11.4 0.3 1.6 1 0 0 1 1 1 0 Coiled stalk of trimeric autotransporter adhesin DUF1272 PF06906.11 PRP83035.1 - 0.15 12.2 6.4 0.43 10.7 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-ANAPC11 PF12861.7 PRP83035.1 - 0.25 11.4 4.5 0.54 10.3 4.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 PRP83035.1 - 0.32 10.9 2.6 0.6 10.0 2.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 PRP83035.1 - 0.42 10.7 5.7 1.2 9.3 5.7 1.8 1 0 0 1 1 1 0 Double zinc ribbon KxDL PF10241.9 PRP83035.1 - 3.7 7.9 11.7 3.8 7.9 7.4 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein CLU PF13236.6 PRP83038.1 - 2.6e-54 184.4 0.0 1e-53 182.5 0.0 1.9 2 0 0 2 2 2 1 Clustered mitochondria PCRF PF03462.18 PRP83038.1 - 0.058 13.3 0.3 0.24 11.3 0.3 2.0 1 0 0 1 1 1 0 PCRF domain Glyco_transf_7N PF13733.6 PRP83038.1 - 0.064 12.9 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 TRAPP PF04051.16 PRP83039.1 - 2.8e-41 140.6 0.1 3.5e-41 140.3 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Peptidase_S10 PF00450.22 PRP83040.1 - 1.3e-73 248.9 2.5 2.2e-72 244.8 2.5 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase ubiquitin PF00240.23 PRP83040.1 - 4.3e-11 42.4 0.0 8.8e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP83040.1 - 8.7e-05 22.3 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_S28 PF05577.12 PRP83040.1 - 0.005 15.7 0.1 0.0085 14.9 0.1 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 PRP83040.1 - 0.0076 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP83040.1 - 0.012 15.2 0.0 0.039 13.6 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF3712 PF12505.8 PRP83043.1 - 1.7e-39 134.9 9.1 3.7e-16 59.5 0.1 4.7 4 0 0 4 4 4 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 PRP83043.1 - 0.044 14.3 8.2 12 6.5 0.1 5.9 6 1 2 8 8 8 0 Late embryogenesis abundant protein TatC PF00902.18 PRP83043.1 - 0.074 12.9 1.5 0.21 11.4 0.2 2.1 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) COPI_assoc PF08507.10 PRP83044.1 - 2e-06 27.9 1.8 3.2e-06 27.2 1.8 1.3 1 1 0 1 1 1 1 COPI associated protein DUF2280 PF10045.9 PRP83045.1 - 0.19 12.0 0.0 0.45 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) MiAMP1 PF09117.10 PRP83045.1 - 0.58 10.4 5.1 17 5.7 0.1 3.0 2 2 2 4 4 4 0 MiAMP1 PKD_channel PF08016.12 PRP83046.1 - 3.8e-06 25.9 8.8 3.8e-06 25.9 8.8 1.5 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 PRP83046.1 - 0.00088 18.6 15.8 0.0028 16.9 15.9 1.8 1 1 0 1 1 1 1 Ion transport protein DASH_Dam1 PF08653.10 PRP83046.1 - 0.43 10.4 1.8 5.3 6.9 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 BLOC1_2 PF10046.9 PRP83046.1 - 0.77 10.1 6.5 0.36 11.2 0.5 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_2 PF07719.17 PRP83047.1 - 4.7e-15 54.4 1.9 0.052 13.7 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 PRP83047.1 - 1.9e-14 52.8 4.3 0.00058 19.6 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83047.1 - 2.8e-13 50.2 2.2 0.0034 17.8 0.3 7.4 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP83047.1 - 4.8e-11 42.5 3.5 0.34 11.8 0.0 7.0 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP83047.1 - 6.4e-11 41.8 1.3 0.046 13.4 0.0 6.3 7 0 0 7 7 7 2 TPR repeat TPR_8 PF13181.6 PRP83047.1 - 1.8e-10 40.2 5.0 0.083 13.1 0.0 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP83047.1 - 9.3e-09 34.7 0.1 0.006 16.5 0.0 6.0 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP83047.1 - 2.2e-08 34.2 2.0 5.3 7.9 0.0 7.4 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP83047.1 - 2.3e-08 34.2 4.9 0.023 15.0 0.0 6.2 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP83047.1 - 4.4e-08 33.2 2.0 0.31 11.2 0.0 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP83047.1 - 6.6e-08 32.7 2.5 0.39 11.0 0.1 5.6 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PRP83047.1 - 7.1e-07 29.8 1.6 0.0087 16.7 0.0 5.9 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 PRP83047.1 - 7.4e-06 25.4 0.7 0.0066 15.7 0.2 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 PRP83047.1 - 0.001 19.1 0.4 1.4 9.1 0.0 4.0 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Mad3_BUB1_I PF08311.12 PRP83047.1 - 0.2 11.7 1.2 11 6.0 0.1 3.1 3 0 0 3 3 2 0 Mad3/BUB1 homology region 1 CDC27 PF09507.10 PRP83047.1 - 0.61 9.4 17.1 0.97 8.7 17.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 PRP83047.1 - 7.5 4.7 12.9 12 4.1 12.9 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 PRP83048.1 - 2.5e-24 85.1 4.2 5.7e-06 27.0 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Bromodomain PF00439.25 PRP83048.1 - 1.7e-17 63.2 0.0 4.6e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain NUDIX PF00293.28 PRP83048.1 - 1.9e-16 60.3 0.8 6.3e-16 58.6 0.1 2.3 2 0 0 2 2 2 1 NUDIX domain ANAPC4_WD40 PF12894.7 PRP83048.1 - 1.3e-06 28.6 0.0 1.6 9.1 0.0 5.7 2 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain NUDIX_4 PF14815.6 PRP83048.1 - 0.091 12.8 0.1 0.5 10.4 0.0 2.3 2 1 0 2 2 2 0 NUDIX domain Ribosomal_L11_N PF03946.14 PRP83049.1 - 3.2e-21 74.9 0.2 6e-21 74.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 PRP83049.1 - 7e-16 58.5 0.3 1.1e-15 57.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain YicC_N PF03755.13 PRP83049.1 - 0.037 14.5 0.1 0.052 14.0 0.1 1.1 1 0 0 1 1 1 0 YicC-like family, N-terminal region adh_short PF00106.25 PRP83051.1 - 5.1e-09 35.9 0.0 1.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP83051.1 - 3.1e-06 26.9 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP83053.1 - 2e-28 99.2 0.0 8.8e-21 74.3 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP83053.1 - 2.3e-17 63.4 0.0 3.8e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP83053.1 - 8.1e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP83053.1 - 0.031 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L11_N PF03946.14 PRP83056.1 - 1.5e-21 76.0 0.3 2e-21 75.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DUF4395 PF14340.6 PRP83057.1 - 2.2e-24 86.2 9.0 2.9e-24 85.9 9.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4395) Wzy_C PF04932.15 PRP83057.1 - 2.4 7.8 5.3 2.3 7.8 0.2 2.3 2 0 0 2 2 2 0 O-Antigen ligase DUF4395 PF14340.6 PRP83059.1 - 4.4e-23 82.1 8.3 4.4e-23 82.1 8.3 2.7 2 1 2 4 4 4 1 Domain of unknown function (DUF4395) Ribosomal_L12_N PF16320.5 PRP83060.1 - 0.17 11.6 1.2 0.23 11.2 1.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain DUF4395 PF14340.6 PRP83061.1 - 2.9e-23 82.6 10.5 2.9e-23 82.6 10.5 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4395) PIP5K PF01504.18 PRP83062.1 - 8.8e-66 221.9 0.8 3.5e-65 219.9 0.1 2.3 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Frizzled PF01534.17 PRP83062.1 - 2.7e-08 33.3 7.9 6.4e-08 32.0 7.9 1.5 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_1 PF00001.21 PRP83062.1 - 1.9e-06 27.4 6.7 3.4e-06 26.6 6.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 PRP83062.1 - 0.0041 16.3 2.5 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor DUF3687 PF12459.8 PRP83063.1 - 1.2 8.7 3.6 1.2 8.8 0.7 2.3 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein DUF3682 PF12446.8 PRP83063.1 - 6.5 7.2 8.0 9.2 6.8 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF4611 PF15387.6 PRP83064.1 - 0.0024 18.0 2.0 0.0035 17.5 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) YbaB_DNA_bd PF02575.16 PRP83064.1 - 0.012 15.8 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Neisseria_PilC PF05567.11 PRP83065.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain GRAM PF02893.20 PRP83066.1 - 0.00023 21.0 0.4 0.00054 19.8 0.4 1.7 1 1 0 1 1 1 1 GRAM domain Guanylate_cyc PF00211.20 PRP83067.1 - 2.9e-15 56.4 0.0 1.1e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 PRP83067.1 - 4.7e-12 46.6 0.0 1.5e-11 44.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PRP83067.1 - 0.0014 18.9 0.2 0.07 13.4 0.1 3.4 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 PRP83067.1 - 0.0023 17.1 1.1 0.39 9.9 0.5 2.4 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 PRP83067.1 - 0.017 15.1 0.1 7.3 6.5 0.0 2.8 2 0 0 2 2 2 0 NACHT domain RPN7 PF10602.9 PRP83067.1 - 0.028 14.1 0.1 0.48 10.1 0.0 2.9 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_7 PF13176.6 PRP83067.1 - 0.061 13.4 3.5 1.3 9.2 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP83067.1 - 0.55 10.5 5.6 1.9 8.7 0.1 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 PRP83067.1 - 1.2 9.1 5.9 15 5.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP83067.1 - 2.3 8.5 10.4 10 6.5 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Synapsin_C PF02750.14 PRP83068.1 - 5.2e-40 137.1 0.0 7e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 PRP83068.1 - 2.1e-14 53.6 0.0 1.8e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 Synapsin, N-terminal domain REJ PF02010.15 PRP83069.1 - 2.5e-37 128.8 12.1 2.5e-37 128.8 12.1 3.6 3 1 1 4 4 4 2 REJ domain LRR_4 PF12799.7 PRP83069.1 - 0.00036 20.9 8.2 0.0055 17.1 0.5 4.4 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP83069.1 - 0.0034 17.9 6.6 0.0034 17.9 3.4 2.8 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_8 PF13855.6 PRP83069.1 - 0.0046 16.7 3.1 0.019 14.7 1.2 2.9 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 PRP83069.1 - 0.045 13.8 1.0 9.7 6.5 0.1 4.3 2 1 1 3 3 3 0 Leucine Rich repeat Mucin_bdg PF03272.13 PRP83069.1 - 0.066 13.3 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Putative mucin or carbohydrate-binding module TSP_3 PF02412.18 PRP83069.1 - 0.5 10.1 11.6 1.2 8.9 6.5 2.7 2 0 0 2 2 2 0 Thrombospondin type 3 repeat DUF296 PF03479.15 PRP83070.1 - 1.6e-24 86.3 0.1 1.8e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Thaumatin PF00314.17 PRP83071.1 - 5.6e-49 166.7 15.2 5.1e-46 157.0 9.2 2.0 1 1 1 2 2 2 2 Thaumatin family TIG PF01833.24 PRP83072.1 - 1.5e-05 25.0 0.0 3.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 IPT/TIG domain LAG1-DNAbind PF09271.11 PRP83072.1 - 0.19 12.4 0.4 16 6.1 0.0 3.2 3 0 0 3 3 3 0 LAG1, DNA binding MIP PF00230.20 PRP83073.1 - 1.3e-65 221.3 17.5 1.7e-65 220.9 17.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein HECT PF00632.25 PRP83074.1 - 7.4e-70 235.9 0.1 4.3e-69 233.3 0.1 2.3 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.17 PRP83074.1 - 2.6e-13 49.5 22.4 4e-07 29.7 6.7 2.8 2 0 0 2 2 2 2 Zinc finger, ZZ type ATP_transf PF09830.9 PRP83074.1 - 0.084 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 ATP adenylyltransferase Vac14_Fab1_bd PF12755.7 PRP83074.1 - 0.13 12.9 0.0 0.59 10.8 0.0 2.2 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region RasGEF PF00617.19 PRP83075.1 - 2.1e-49 168.1 1.6 5.3e-49 166.8 1.6 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP83075.1 - 0.00019 21.6 5.0 0.00076 19.7 2.0 3.1 2 1 0 2 2 2 1 RasGEF N-terminal motif IQ PF00612.27 PRP83075.1 - 0.0083 15.8 5.8 0.49 10.3 1.1 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif BBS1 PF14779.6 PRP83077.1 - 5.3e-76 255.4 0.1 1.1e-74 251.1 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 PRP83077.1 - 2.4e-08 34.0 0.0 0.00024 21.1 0.0 2.8 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 PRP83077.1 - 0.00023 20.7 0.0 0.023 14.1 0.0 2.6 3 0 0 3 3 3 1 PTHB1 N-terminus Mcl1_mid PF12341.8 PRP83077.1 - 0.058 12.7 0.1 0.22 10.9 0.1 1.9 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Cuticle_1 PF08140.11 PRP83077.1 - 0.17 11.9 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Crustacean cuticle protein repeat OPA3 PF07047.12 PRP83079.1 - 8.1e-36 122.6 0.3 8.1e-36 122.6 0.3 1.5 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) Yae1_N PF09811.9 PRP83080.1 - 1.1 9.0 6.1 2.4 7.9 6.1 1.5 1 1 0 1 1 1 0 Essential protein Yae1, N terminal Acetyltransf_10 PF13673.7 PRP83081.1 - 1.2e-10 41.4 0.0 2.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP83081.1 - 6e-10 39.4 0.0 1.5e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP83081.1 - 1.3e-07 31.5 0.1 1e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 PRP83081.1 - 1.6e-07 31.6 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 PRP83081.1 - 3.5e-05 23.5 0.0 7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_9 PF13527.7 PRP83081.1 - 0.00014 21.9 0.0 0.00037 20.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 PRP83081.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 PRP83081.1 - 0.013 15.4 0.1 0.038 14.0 0.1 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.7 PRP83081.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ephrin_rec_like PF07699.13 PRP83081.1 - 1.5 8.7 19.3 0.047 13.5 4.9 3.0 3 0 0 3 3 3 0 Putative ephrin-receptor like NCD3G PF07562.14 PRP83081.1 - 1.8 8.6 15.1 0.043 13.8 1.4 3.1 2 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Pkinase PF00069.25 PRP83082.1 - 2.6e-70 236.8 0.0 3.6e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83082.1 - 1.6e-35 122.6 0.0 2.4e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.7 PRP83082.1 - 1.7e-13 50.7 0.0 8.4e-05 22.8 0.0 4.4 4 0 0 4 4 4 2 PAS domain RIO1 PF01163.22 PRP83082.1 - 4.4e-07 29.7 0.3 7e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PRP83082.1 - 5.9e-06 25.8 0.0 2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP83082.1 - 6.3e-06 25.7 0.1 9.9e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 PRP83082.1 - 3.3e-05 24.1 0.0 1.1 9.5 0.0 3.9 4 0 0 4 4 4 2 PAS fold PAS_3 PF08447.12 PRP83082.1 - 0.00011 22.4 0.0 35 4.8 0.0 4.9 5 0 0 5 5 5 0 PAS fold PAS PF00989.25 PRP83082.1 - 0.0033 17.4 0.0 0.24 11.4 0.0 3.5 4 0 0 4 4 4 1 PAS fold APH PF01636.23 PRP83082.1 - 0.0052 16.7 0.1 0.0087 16.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP83082.1 - 0.0071 15.2 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP83082.1 - 0.0095 14.9 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PAS_8 PF13188.7 PRP83082.1 - 0.036 14.1 0.0 8 6.6 0.0 2.8 3 0 0 3 3 3 0 PAS domain Choline_kinase PF01633.20 PRP83082.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Atg8 PF02991.16 PRP83083.1 - 2.7e-44 149.6 0.5 4.1e-44 149.0 0.1 1.5 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 PRP83083.1 - 1.8e-06 28.2 0.2 9.4e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 DUF2254 PF10011.9 PRP83084.1 - 4.1e-12 45.6 6.4 7.1e-12 44.8 6.4 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) KAP_NTPase PF07693.14 PRP83084.1 - 0.13 11.5 0.5 0.78 8.9 0.1 2.1 2 0 0 2 2 2 0 KAP family P-loop domain Neurensin PF14927.6 PRP83084.1 - 0.35 10.6 6.4 0.3 10.8 0.2 2.5 1 1 0 2 2 2 0 Neurensin zf-C4 PF00105.18 PRP83085.1 - 0.021 15.3 2.0 0.94 10.0 0.6 3.0 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) PPP1R35_C PF15503.6 PRP83085.1 - 0.046 13.5 0.1 0.093 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Peptidase_S49 PF01343.18 PRP83087.1 - 6e-66 221.1 0.0 6.9e-37 126.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 SDH_sah PF01972.16 PRP83087.1 - 2.5e-08 33.3 0.0 4.1e-05 22.7 0.1 2.2 2 0 0 2 2 2 2 Serine dehydrogenase proteinase CLP_protease PF00574.23 PRP83087.1 - 3.6e-06 27.0 0.7 0.00018 21.5 0.2 2.7 3 0 0 3 3 3 1 Clp protease Ligase_CoA PF00549.19 PRP83087.1 - 0.079 12.8 0.1 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 CoA-ligase ECH_1 PF00378.20 PRP83087.1 - 0.096 12.0 1.0 15 4.8 0.3 3.6 2 2 0 2 2 2 0 Enoyl-CoA hydratase/isomerase RicinB_lectin_2 PF14200.6 PRP83088.1 - 3e-11 43.9 0.8 4.9e-07 30.4 0.0 3.5 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 PRP83088.1 - 0.0041 17.4 0.1 0.0095 16.2 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain VWA_N2 PF16164.5 PRP83088.1 - 0.18 11.9 0.7 0.62 10.3 0.0 2.1 2 0 0 2 2 2 0 VWA N-terminal Dmrt1 PF12374.8 PRP83088.1 - 0.62 10.5 5.9 1.7 9.1 5.9 1.8 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 Kelch_1 PF01344.25 PRP83088.1 - 1.1 9.0 4.7 19 4.9 0.6 2.9 3 0 0 3 3 3 0 Kelch motif ubiquitin PF00240.23 PRP83089.1 - 0.09 12.5 1.3 0.34 10.7 1.3 1.9 1 1 0 1 1 1 0 Ubiquitin family Gpr1_Fun34_YaaH PF01184.19 PRP83090.1 - 3.7e-46 157.4 21.7 4.8e-46 157.0 21.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RTX PF02382.15 PRP83090.1 - 0.001 18.9 0.4 0.0018 18.0 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain in RTX protein RhoGAP PF00620.27 PRP83091.1 - 4.5e-18 65.5 0.1 4.7e-17 62.2 0.0 2.6 3 1 1 4 4 4 1 RhoGAP domain GRAM PF02893.20 PRP83091.1 - 0.025 14.4 1.0 0.41 10.6 0.1 2.5 2 0 0 2 2 2 0 GRAM domain VbhA PF18495.1 PRP83091.1 - 0.063 13.2 0.3 0.17 11.8 0.3 1.7 1 0 0 1 1 1 0 Antitoxin VbhA DUF3568 PF12092.8 PRP83091.1 - 0.079 13.0 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF1707 PF08044.11 PRP83091.1 - 0.14 12.3 0.5 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) ApoB100_C PF12491.8 PRP83091.1 - 3.4 7.7 7.1 0.41 10.6 0.4 2.9 4 0 0 4 4 4 0 Apolipoprotein B100 C terminal Peptidase_C48 PF02902.19 PRP83092.1 - 1.5e-34 119.7 0.0 2.8e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SlyX PF04102.12 PRP83092.1 - 0.22 12.1 1.9 0.95 10.1 1.9 2.0 1 0 0 1 1 1 0 SlyX CobT PF06213.12 PRP83092.1 - 6.8 6.0 22.0 0.13 11.7 11.1 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Afi1 PF07792.12 PRP83092.1 - 8.1 6.9 9.9 2.3 8.7 1.8 2.9 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Glyco_hydro_3_C PF01915.22 PRP83093.1 - 1.1e-50 172.5 0.0 1.8e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain PA14 PF07691.12 PRP83093.1 - 1.9e-17 63.4 0.0 3.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 PRP83093.1 - 0.00017 21.6 0.0 0.00054 20.0 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 PRP83093.1 - 0.0057 16.9 0.1 0.02 15.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF11 EGF_2 PF07974.13 PRP83096.1 - 9.8e-12 45.0 58.0 1.4e-05 25.4 13.2 3.5 3 0 0 3 3 3 3 EGF-like domain TIG PF01833.24 PRP83096.1 - 0.00049 20.1 0.7 0.00097 19.2 0.7 1.5 1 0 0 1 1 1 1 IPT/TIG domain Laminin_EGF PF00053.24 PRP83096.1 - 0.046 13.9 44.2 0.41 10.8 6.2 3.3 2 1 1 3 3 3 0 Laminin EGF domain EGF PF00008.27 PRP83096.1 - 0.17 12.2 48.0 0.15 12.4 10.7 3.9 3 0 0 3 3 3 0 EGF-like domain EGF_Tenascin PF18720.1 PRP83096.1 - 0.93 9.6 45.4 0.32 11.1 8.4 3.6 3 0 0 3 3 3 0 Tenascin EGF domain Glyco_hydro_71 PF03659.14 PRP83097.1 - 7.5e-82 275.1 22.1 1.2e-81 274.5 22.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Pur_ac_phosph_N PF16656.5 PRP83097.1 - 0.013 16.0 0.7 0.24 12.0 0.0 2.6 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain CRAL_TRIO PF00650.20 PRP83098.1 - 2.8e-27 95.4 0.0 4.6e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PRP83098.1 - 4.2e-11 43.2 0.0 7.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP83098.1 - 0.067 13.4 0.8 0.21 11.8 0.8 1.9 1 1 0 1 1 1 0 CRAL/TRIO, N-terminal domain CLASP_N PF12348.8 PRP83099.1 - 2.3e-05 24.1 0.2 3.8e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 CLASP N terminal UVR PF02151.19 PRP83099.1 - 0.0016 18.1 12.2 0.0094 15.7 5.2 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif MAM1 PF10434.9 PRP83099.1 - 0.0055 16.3 0.5 0.0055 16.3 0.5 2.2 2 0 0 2 2 2 1 Monopolin complex protein MAM1 XRCC1_N PF01834.16 PRP83099.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 XRCC1 N terminal domain RasGEF_N_2 PF14663.6 PRP83099.1 - 0.13 12.7 0.2 0.72 10.3 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 PRP83099.1 - 0.21 11.9 0.5 26 5.4 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Prok-RING_4 PF14447.6 PRP83099.1 - 0.49 10.3 4.8 3.1 7.7 0.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Sugar_tr PF00083.24 PRP83100.1 - 4.5e-111 371.9 24.5 5.6e-111 371.6 24.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP83100.1 - 2.2e-29 102.5 34.3 2.1e-21 76.2 13.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF973 PF06157.11 PRP83101.1 - 0.25 10.4 8.9 0.14 11.2 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) NARG2_C PF10505.9 PRP83102.1 - 5.1e-19 68.6 0.1 9.9e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Pkinase PF00069.25 PRP83104.1 - 8.9e-65 218.7 0.2 1.1e-64 218.4 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83104.1 - 1.2e-30 106.6 0.2 1.7e-30 106.2 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP83104.1 - 2e-10 40.4 0.0 2.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP83104.1 - 2.2e-09 36.7 0.3 3.1e-09 36.3 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP83104.1 - 4.2e-06 26.9 0.2 0.0087 16.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP83104.1 - 4.3e-06 26.2 0.3 6.1e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP83104.1 - 2e-05 24.3 0.6 3.6e-05 23.5 0.5 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase D123 PF07065.14 PRP83104.1 - 0.038 13.1 0.1 0.055 12.6 0.1 1.1 1 0 0 1 1 1 0 D123 SRP19 PF01922.17 PRP83105.1 - 3.4e-27 95.2 0.1 4e-27 95.0 0.1 1.1 1 0 0 1 1 1 1 SRP19 protein Pkinase PF00069.25 PRP83106.1 - 5.1e-65 219.5 0.0 6e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83106.1 - 1.2e-43 149.3 0.0 1.4e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP83106.1 - 1.6e-06 27.7 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP83106.1 - 2.8e-06 27.5 0.1 0.0053 16.7 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP83106.1 - 1.8e-05 24.2 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP83106.1 - 0.0081 15.1 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP83106.1 - 0.022 13.5 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PLDc_2 PF13091.6 PRP83108.1 - 4.7e-12 45.9 0.2 6.2e-10 39.1 0.1 3.2 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 PRP83108.1 - 7.3e-11 41.8 0.6 0.00024 21.2 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif BBS2_C PF14782.6 PRP83109.1 - 8.7e-115 383.9 10.2 2e-112 376.1 9.3 3.3 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_N PF14781.6 PRP83109.1 - 1.1e-32 112.0 0.1 1.2e-31 108.7 0.0 2.8 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.6 PRP83109.1 - 4.5e-30 103.9 0.2 1e-27 96.3 0.0 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 PRP83109.1 - 3.5e-06 26.3 0.1 0.038 13.0 0.0 3.3 1 1 2 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 PRP83109.1 - 0.065 13.4 1.2 0.34 11.1 0.0 2.7 3 0 0 3 3 3 0 FG-GAP repeat DUF4407 PF14362.6 PRP83109.1 - 0.58 9.5 3.3 1 8.6 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1748 PF08520.10 PRP83110.1 - 4.8e-08 32.8 0.0 5.6e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Flagellin_IN PF07196.13 PRP83110.1 - 0.08 13.1 1.6 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 Flagellin hook IN motif PDEase_I PF00233.19 PRP83111.1 - 1.2e-84 283.7 0.0 2.8e-84 282.5 0.0 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase MitMem_reg PF13012.6 PRP83111.1 - 1e-27 96.8 0.4 3.5e-27 95.0 0.0 2.2 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PRP83111.1 - 4.4e-21 75.0 0.1 9.5e-21 74.0 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CK2S PF15011.6 PRP83111.1 - 0.018 14.9 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate DivIC PF04977.15 PRP83111.1 - 0.077 12.8 0.5 0.21 11.4 0.5 1.7 1 0 0 1 1 1 0 Septum formation initiator VPS28 PF03997.12 PRP83112.1 - 3.2e-58 196.5 0.4 4e-58 196.2 0.4 1.1 1 0 0 1 1 1 1 VPS28 protein TerB_N PF13208.6 PRP83112.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 TerB N-terminal domain BUD22 PF09073.10 PRP83113.1 - 0.89 8.8 31.2 0.95 8.7 31.2 1.0 1 0 0 1 1 1 0 BUD22 AF-4 PF05110.13 PRP83113.1 - 7.5 4.5 21.2 7.5 4.5 21.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SAM_2 PF07647.17 PRP83114.1 - 0.096 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Astro_capsid_N PF03115.14 PRP83114.1 - 0.1 11.3 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pkinase PF00069.25 PRP83115.1 - 1.8e-09 37.3 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PRP83115.1 - 6.1e-08 32.0 0.0 9.3e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP83115.1 - 0.001 19.1 0.1 0.096 12.6 0.1 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP83115.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 PRP83115.1 - 0.0093 15.3 0.0 0.13 11.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase GRAM PF02893.20 PRP83116.1 - 1.2e-22 79.9 0.1 2.8e-22 78.7 0.1 1.6 1 0 0 1 1 1 1 GRAM domain VASt PF16016.5 PRP83116.1 - 5.2e-21 75.7 0.0 1.5e-20 74.2 0.0 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF1206 PF06724.11 PRP83116.1 - 0.012 15.7 1.4 0.018 15.1 0.3 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) Ribosomal_L3 PF00297.22 PRP83118.1 - 6.2e-169 561.8 11.5 7e-169 561.6 11.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Wyosine_form PF08608.12 PRP83119.1 - 3.5e-25 88.1 0.1 9.1e-25 86.8 0.1 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 PRP83119.1 - 8.3e-25 88.1 0.0 1.4e-24 87.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 PRP83119.1 - 9.6e-23 81.0 0.1 4e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_5 PF12724.7 PRP83119.1 - 0.0061 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_NdrI PF07972.11 PRP83119.1 - 0.063 13.5 0.3 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 NrdI Flavodoxin like Neur_chan_memb PF02932.16 PRP83119.1 - 0.17 11.9 2.3 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_3_Rpc31 PF11705.8 PRP83119.1 - 0.69 10.1 16.7 1.3 9.2 16.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SURF2 PF05477.11 PRP83119.1 - 0.72 9.5 10.1 1.7 8.2 10.1 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PGA2 PF07543.12 PRP83119.1 - 10 6.1 12.6 29 4.6 11.8 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Phosphonate-bd PF12974.7 PRP83120.1 - 3.6e-07 30.0 1.4 4.4e-07 29.8 0.2 1.7 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 PRP83120.1 - 3.4e-05 23.9 0.0 6.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like EB PF01683.18 PRP83121.1 - 0.059 13.7 0.8 0.059 13.7 0.8 1.6 2 0 0 2 2 2 0 EB module EGF_2 PF07974.13 PRP83121.1 - 0.1 13.0 5.2 0.21 12.0 5.2 1.5 1 0 0 1 1 1 0 EGF-like domain EGF PF00008.27 PRP83121.1 - 0.21 11.9 6.4 0.41 11.0 6.4 1.5 1 0 0 1 1 1 0 EGF-like domain NTP_transf_9 PF04248.12 PRP83122.1 - 3.5e-35 119.8 0.3 1.2e-34 118.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF427) ABC1 PF03109.16 PRP83123.1 - 3.4e-30 104.6 0.0 6.7e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PRP83123.1 - 0.02 14.8 0.1 0.053 13.4 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 PRP83123.1 - 0.025 13.9 0.0 0.082 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain WaaY PF06176.11 PRP83123.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) LCAT PF02450.15 PRP83124.1 - 3.9e-50 171.2 0.4 1.4e-49 169.3 0.4 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 PRP83124.1 - 4.6e-06 26.5 0.0 8.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 PRP83124.1 - 0.083 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 PRP83124.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Exo_endo_phos PF03372.23 PRP83125.1 - 9.6e-11 41.6 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Fib_alpha PF08702.10 PRP83125.1 - 2.2 8.4 7.7 0.19 11.9 2.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IFT46_B_C PF12317.8 PRP83126.1 - 1.6e-77 260.0 0.5 2.3e-77 259.5 0.5 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal DUF4746 PF15928.5 PRP83126.1 - 2.6 7.4 6.3 4.8 6.5 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3449 PF11931.8 PRP83126.1 - 2.6 7.8 7.1 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Cpn60_TCP1 PF00118.24 PRP83127.1 - 7.5e-143 476.7 9.5 8.9e-143 476.5 9.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_43 PF04616.14 PRP83127.1 - 2.1e-50 171.7 6.9 3e-50 171.2 6.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PAN_4 PF14295.6 PRP83127.1 - 3.2e-08 33.4 8.4 0.00015 21.6 3.3 3.2 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 PRP83127.1 - 0.21 11.6 2.2 0.46 10.5 2.2 1.6 1 0 0 1 1 1 0 PAN domain Mito_carr PF00153.27 PRP83128.1 - 5.9e-61 202.4 0.4 3.3e-19 68.6 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 PRP83128.1 - 4.7e-16 59.0 0.1 1.4e-07 31.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP83128.1 - 2.9e-14 51.5 0.8 0.00042 19.7 0.0 4.1 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PRP83128.1 - 2.5e-12 45.7 1.6 0.00065 19.4 0.0 4.1 4 0 0 4 4 3 3 EF-hand domain LRR_6 PF13516.6 PRP83128.1 - 1.3e-06 28.0 20.4 0.00044 20.1 0.2 7.8 9 0 0 9 9 7 2 Leucine Rich repeat EF-hand_5 PF13202.6 PRP83128.1 - 1.9e-06 27.1 0.8 0.0017 17.8 0.0 3.5 3 1 0 3 3 3 1 EF hand LRR_8 PF13855.6 PRP83128.1 - 0.00012 21.8 8.7 0.013 15.2 0.3 5.3 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 PRP83128.1 - 0.001 19.4 22.7 0.2 12.2 1.1 6.8 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) EF-hand_8 PF13833.6 PRP83128.1 - 0.0019 18.0 0.1 1.5 8.8 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP83128.1 - 0.0031 17.8 0.1 4.2 7.7 0.2 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pox_C4_C10 PF03336.13 PRP83128.1 - 0.021 13.9 0.0 0.053 12.6 0.0 1.6 1 0 0 1 1 1 0 Poxvirus C4/C10 protein EF-hand_9 PF14658.6 PRP83128.1 - 0.17 12.3 0.0 0.84 10.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain HrpF PF06266.12 PRP83128.1 - 0.44 10.9 1.8 1.3 9.3 1.8 1.9 1 0 0 1 1 1 0 HrpF protein LRR_1 PF00560.33 PRP83128.1 - 1.5 9.7 16.7 17 6.4 0.0 7.6 9 0 0 9 9 8 0 Leucine Rich Repeat Ras PF00071.22 PRP83129.1 - 1.7e-58 196.8 0.3 5.8e-58 195.1 0.4 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP83129.1 - 1.2e-31 109.4 0.2 3.7e-31 107.9 0.2 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP83129.1 - 6.5e-15 55.0 0.2 1.8e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP83129.1 - 4.5e-05 22.9 0.1 8.6e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region VWA_2 PF13519.6 PRP83129.1 - 0.00035 21.2 0.0 0.061 14.0 0.0 3.4 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-Sec23_Sec24 PF04810.15 PRP83129.1 - 0.00046 20.2 0.2 0.076 13.1 0.1 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger MMR_HSR1 PF01926.23 PRP83129.1 - 0.0017 18.4 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Sec23_trunk PF04811.15 PRP83129.1 - 0.0089 15.6 0.1 0.089 12.4 0.1 2.3 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain RsgA_GTPase PF03193.16 PRP83129.1 - 0.0092 15.9 0.1 0.86 9.5 0.0 2.5 1 1 0 2 2 2 1 RsgA GTPase VWA PF00092.28 PRP83129.1 - 0.11 12.7 0.1 4.9 7.4 0.1 3.1 1 1 0 1 1 1 0 von Willebrand factor type A domain Sec23_BS PF08033.12 PRP83129.1 - 0.13 13.1 0.0 0.38 11.5 0.0 1.8 1 0 0 1 1 1 0 Sec23/Sec24 beta-sandwich domain AAA_22 PF13401.6 PRP83129.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain P2X_receptor PF00864.19 PRP83130.1 - 9.3e-81 271.7 5.1 9.8e-80 268.4 5.1 1.9 1 1 0 1 1 1 1 ATP P2X receptor Nodulin_late PF07127.11 PRP83130.1 - 0.028 14.7 1.0 0.077 13.3 1.0 1.8 1 0 0 1 1 1 0 Late nodulin protein DUF4636 PF15468.6 PRP83130.1 - 0.057 13.1 0.1 0.09 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) F-box-like PF12937.7 PRP83131.1 - 2.6e-10 40.0 0.4 7.8e-10 38.5 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP83131.1 - 6.6e-08 32.2 2.6 2e-07 30.7 2.6 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP83131.1 - 0.00036 20.4 2.4 0.0005 19.9 0.0 2.4 3 0 0 3 3 3 1 F-box PRANC PF09372.10 PRP83131.1 - 0.0072 16.6 0.1 0.091 13.1 0.1 2.6 2 0 0 2 2 2 1 PRANC domain Imm27 PF15590.6 PRP83131.1 - 0.31 10.8 1.5 1.3 8.8 0.3 2.5 1 1 1 2 2 2 0 Immunity protein 27 Cation_efflux PF01545.21 PRP83132.1 - 1.3e-44 152.4 1.9 1.8e-44 151.9 1.9 1.2 1 0 0 1 1 1 1 Cation efflux family V_ATPase_I PF01496.19 PRP83132.1 - 0.0039 15.2 0.0 0.0055 14.7 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CDC45 PF02724.14 PRP83132.1 - 0.0072 14.7 0.2 0.01 14.2 0.2 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF3278 PF11683.8 PRP83132.1 - 0.044 13.9 4.6 0.33 11.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) Sec62 PF03839.16 PRP83132.1 - 0.55 9.7 2.6 0.36 10.3 0.2 1.9 2 0 0 2 2 2 0 Translocation protein Sec62 Macoilin PF09726.9 PRP83132.1 - 2.1 6.8 5.6 2.9 6.3 5.6 1.1 1 0 0 1 1 1 0 Macoilin family ECF_trnsprt PF12822.7 PRP83132.1 - 4.9 7.2 10.5 0.38 10.8 0.4 2.5 2 1 0 2 2 2 0 ECF transporter, substrate-specific component zf-PHD-like PF15446.6 PRP83133.1 - 0.0029 17.3 3.8 0.16 11.5 0.2 2.3 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PAS PF00989.25 PRP83133.1 - 0.004 17.1 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold AP3D1 PF06375.11 PRP83133.1 - 0.015 15.5 9.4 0.035 14.3 7.4 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Connexin PF00029.19 PRP83133.1 - 0.027 14.2 0.6 0.052 13.3 0.6 1.4 1 0 0 1 1 1 0 Connexin DUF2956 PF11169.8 PRP83133.1 - 0.028 14.6 4.6 1.4 9.1 3.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) OATP PF03137.20 PRP83133.1 - 0.041 12.2 0.3 0.061 11.6 0.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PAS_4 PF08448.10 PRP83133.1 - 0.063 13.5 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 PAS fold U79_P34 PF03064.16 PRP83133.1 - 0.088 12.1 6.9 0.16 11.3 6.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Menin PF05053.13 PRP83133.1 - 0.18 10.1 0.8 0.29 9.5 0.8 1.2 1 0 0 1 1 1 0 Menin Jak1_Phl PF17887.1 PRP83133.1 - 0.3 11.1 10.2 1.4 8.8 0.0 2.9 3 0 0 3 3 3 0 Jak1 pleckstrin homology-like domain RR_TM4-6 PF06459.12 PRP83133.1 - 0.62 9.8 7.4 0.15 11.9 3.9 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 PRP83133.1 - 1.3 9.1 20.0 0.12 12.5 14.6 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SMAP PF15477.6 PRP83134.1 - 3.7e-08 34.2 0.8 6.6e-08 33.4 0.8 1.5 1 0 0 1 1 1 1 Small acidic protein family DUF572 PF04502.13 PRP83134.1 - 0.012 15.3 4.4 0.013 15.1 4.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pro_isomerase PF00160.21 PRP83135.1 - 7.5e-45 153.0 0.2 1.4e-44 152.2 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 PRP83135.1 - 5.2e-37 127.6 0.0 9.1e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83135.1 - 4.2e-11 42.6 0.0 7.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.24 PRP83135.1 - 7.8e-10 38.7 0.0 5.9e-07 29.5 0.0 2.8 2 0 0 2 2 2 2 SH2 domain Cbl_N3 PF02762.14 PRP83135.1 - 0.00018 21.3 0.0 0.01 15.6 0.0 2.6 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, SH2-like domain Cbl_N2 PF02761.14 PRP83135.1 - 0.0013 19.4 0.1 0.0059 17.3 0.0 2.2 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain PP2C_2 PF13672.6 PRP83135.1 - 0.0022 17.6 0.0 0.27 10.8 0.0 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP83135.1 - 0.013 15.4 0.1 0.24 11.3 0.0 2.9 3 1 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Kinase-like PF14531.6 PRP83135.1 - 0.14 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like IBP39 PF11422.8 PRP83135.1 - 0.18 11.5 0.0 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 Initiator binding protein 39 kDa HMG_box_2 PF09011.10 PRP83136.1 - 0.017 15.7 1.3 0.83 10.3 0.3 2.1 1 1 1 2 2 2 0 HMG-box domain Chromo PF00385.24 PRP83137.1 - 1.9e-13 50.1 0.0 2.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP83137.1 - 0.038 14.2 0.5 0.061 13.5 0.5 1.4 1 1 0 1 1 1 0 Polycomb-like MTF2 factor 2 Beta-Casp PF10996.8 PRP83139.1 - 8.7e-23 80.7 0.0 4.3e-22 78.5 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 PRP83139.1 - 9.3e-18 63.9 0.0 2.2e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 PRP83139.1 - 4e-12 46.0 0.1 1.4e-11 44.2 0.1 1.9 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 PRP83139.1 - 0.0078 15.7 0.1 0.12 11.8 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP83139.1 - 0.036 14.1 0.1 0.59 10.1 0.0 2.7 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily GPI PF06560.11 PRP83140.1 - 0.059 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Zn_peptidase_2 PF04298.12 PRP83141.1 - 0.081 12.3 0.7 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Hist_deacetyl PF00850.19 PRP83144.1 - 1.3e-72 244.9 0.1 2.6e-72 243.9 0.1 1.6 1 0 0 1 1 1 1 Histone deacetylase domain JmjC PF02373.22 PRP83144.1 - 3.4e-41 140.2 0.2 3.4e-41 140.2 0.2 2.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 PRP83144.1 - 8e-12 44.9 0.9 2.8e-11 43.2 0.9 2.0 1 0 0 1 1 1 1 jmjN domain FHA_2 PF17913.1 PRP83144.1 - 0.0007 19.8 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain DCB PF16213.5 PRP83144.1 - 0.048 13.3 0.3 0.11 12.2 0.3 1.6 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 FHA PF00498.26 PRP83144.1 - 0.091 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 FHA domain MGDG_synth PF06925.11 PRP83147.1 - 3.8e-09 36.9 0.0 4.4e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Epimerase_2 PF02350.19 PRP83147.1 - 0.058 12.3 0.0 0.074 11.9 0.0 1.0 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF2866 PF11065.8 PRP83151.1 - 0.01 15.8 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2866) TPD52 PF04201.15 PRP83151.1 - 0.042 13.4 5.0 0.053 13.1 5.0 1.1 1 0 0 1 1 1 0 Tumour protein D52 family Glyco_transf_41 PF13844.6 PRP83152.1 - 6.6e-63 212.8 1.1 2.1e-31 108.9 0.0 2.5 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_14 PF13428.6 PRP83152.1 - 0.097 13.5 0.3 0.81 10.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP83152.1 - 2 8.7 8.5 4.3 7.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 PRP83153.1 - 9.8e-35 120.1 0.0 1.5e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PRP83153.1 - 1.9e-06 27.7 0.0 3.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 PRP83153.1 - 2e-06 27.6 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M28 FAD-oxidase_C PF02913.19 PRP83154.1 - 3.9e-60 203.6 0.6 2.7e-58 197.6 0.2 2.7 2 1 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PRP83154.1 - 6.6e-29 100.4 0.2 2.6e-28 98.5 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain MMM1 PF10296.9 PRP83155.1 - 1.4e-13 50.6 3.3 3.6e-12 46.0 0.0 3.2 2 1 0 3 3 3 1 Maintenance of mitochondrial morphology protein 1 BRCT_2 PF16589.5 PRP83155.1 - 5.5e-09 36.3 0.0 2.3e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PRP83155.1 - 4.3e-08 33.4 0.0 5.5e-06 26.7 0.0 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PH PF00169.29 PRP83155.1 - 5.4e-06 26.9 0.5 0.045 14.3 0.0 3.7 3 0 0 3 3 3 1 PH domain SnoaL PF07366.12 PRP83155.1 - 6.5e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PTCB-BRCT PF12738.7 PRP83155.1 - 3.2e-05 23.8 0.1 7e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 PRP83155.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Pox_I1 PF03289.13 PRP83155.1 - 0.074 12.2 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Poxvirus protein I1 PH_11 PF15413.6 PRP83155.1 - 1.8 9.0 4.2 4 7.9 0.1 3.4 3 1 0 3 3 3 0 Pleckstrin homology domain Rtf2 PF04641.12 PRP83156.1 - 7.1e-67 225.5 10.6 9.1e-67 225.2 10.6 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger AP3D1 PF06375.11 PRP83156.1 - 0.00091 19.5 2.7 0.0016 18.7 2.7 1.4 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 zf-NOSIP PF15906.5 PRP83156.1 - 0.045 13.9 0.8 0.078 13.1 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein BRF1 PF07741.13 PRP83156.1 - 0.052 13.9 7.3 0.1 12.9 7.3 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2614 PF11023.8 PRP83156.1 - 8.8 6.5 8.6 0.91 9.6 0.5 2.6 2 1 0 2 2 2 0 Zinc-ribbon containing domain UPF0542 PF15086.6 PRP83157.1 - 0.078 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 FmiP_Thoc5 PF09766.9 PRP83158.1 - 2.7e-31 109.2 17.8 1.8e-21 76.8 12.9 2.8 2 1 1 3 3 3 2 Fms-interacting protein/Thoc5 DUF334 PF03904.13 PRP83158.1 - 0.35 10.4 10.0 0.42 10.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF334) Transketolase_N PF00456.21 PRP83159.1 - 4.6e-150 499.2 0.0 6.4e-150 498.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 PRP83159.1 - 2.5e-41 141.3 0.0 4e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PRP83159.1 - 1.7e-07 31.2 0.0 4.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 PRP83159.1 - 0.00025 20.4 0.0 0.0075 15.5 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase zf-C3HC4 PF00097.25 PRP83160.1 - 2.8e-08 33.5 7.8 4.3e-08 32.9 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP83160.1 - 1.6e-07 31.0 8.1 1.6e-07 31.0 8.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP83160.1 - 2e-07 30.9 6.8 6e-06 26.2 3.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP83160.1 - 4.2e-07 29.7 5.3 6.2e-07 29.2 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP83160.1 - 5.2e-07 29.9 9.3 7.7e-07 29.3 9.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PRP83160.1 - 1.2e-06 28.3 5.8 1.8e-06 27.8 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PRP83160.1 - 1.2e-05 25.4 9.7 1.7e-05 24.9 9.7 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PRP83160.1 - 0.00064 19.5 7.9 0.0011 18.8 7.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 PRP83160.1 - 0.11 12.5 1.7 0.15 12.0 1.7 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) U-box PF04564.15 PRP83160.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 U-box domain Rad50_zn_hook PF04423.14 PRP83160.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_6 PF14835.6 PRP83160.1 - 0.23 11.4 3.5 0.4 10.6 3.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.6 PRP83160.1 - 0.32 11.1 1.6 0.69 10.1 1.6 1.6 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 PRP83160.1 - 0.96 9.3 4.7 2.5 8.0 4.7 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-LITAF-like PF10601.9 PRP83160.1 - 5.4 7.4 9.9 6.1 7.2 8.3 2.0 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain LRR_8 PF13855.6 PRP83161.1 - 6.4e-38 128.3 66.8 5.3e-10 38.9 7.4 7.1 5 1 0 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PRP83161.1 - 1.3e-27 95.3 76.8 8.9e-07 29.1 1.3 10.7 6 3 3 11 11 11 9 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP83161.1 - 8.3e-25 87.5 0.1 1.3e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83161.1 - 2.5e-21 76.2 0.3 4.4e-21 75.4 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_1 PF00560.33 PRP83161.1 - 3e-13 48.3 60.9 0.24 12.1 0.3 14.8 13 1 0 13 13 13 9 Leucine Rich Repeat GPS PF01825.21 PRP83161.1 - 4e-08 33.7 0.6 1.1e-07 32.2 0.6 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_6 PF13516.6 PRP83161.1 - 0.11 12.6 53.5 1.4 9.1 0.4 12.2 13 0 0 13 13 13 0 Leucine Rich repeat DUF4506 PF14958.6 PRP83161.1 - 0.13 11.8 0.2 0.34 10.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) LRR_9 PF14580.6 PRP83161.1 - 1.9 8.0 15.6 0.11 12.0 0.4 4.0 3 1 1 4 4 4 0 Leucine-rich repeat RabGAP-TBC PF00566.18 PRP83163.1 - 3e-44 151.3 1.5 3e-44 151.3 1.5 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.32 PRP83163.1 - 2e-11 42.6 1.9 0.00074 18.9 0.1 4.0 3 1 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PRP83163.1 - 1.5e-09 37.0 2.1 0.12 12.3 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 PRP83163.1 - 4.4e-09 36.7 4.6 5.2e-07 30.0 1.8 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP83163.1 - 0.00019 21.2 1.9 0.076 12.9 0.0 3.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP83163.1 - 0.00075 18.9 3.6 0.037 13.5 0.1 4.1 4 0 0 4 4 4 1 EF hand Adeno_terminal PF02459.15 PRP83163.1 - 6 5.1 8.7 14 3.9 8.7 1.6 1 1 0 1 1 1 0 Adenoviral DNA terminal protein Peptidase_A22B PF04258.13 PRP83164.1 - 1.2e-15 57.8 7.9 1.9e-15 57.2 7.9 1.6 1 1 0 1 1 1 1 Signal peptide peptidase Amidohydro_1 PF01979.20 PRP83165.1 - 1.9e-12 47.1 0.1 3e-11 43.2 0.1 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PRP83165.1 - 2.3e-09 37.2 0.0 1.9e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Homeodomain PF00046.29 PRP83166.1 - 1.5e-07 31.1 1.4 2e-07 30.7 0.5 1.7 2 0 0 2 2 2 1 Homeodomain DUF2732 PF10809.8 PRP83166.1 - 0.066 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) RasGEF PF00617.19 PRP83167.1 - 4e-48 164.0 0.1 1.6e-26 93.6 0.1 2.8 1 1 1 2 2 2 2 RasGEF domain DEAD PF00270.29 PRP83167.1 - 4.1e-47 160.2 0.0 1.3e-46 158.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP83167.1 - 1.7e-29 102.4 0.0 6e-29 100.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RasGEF_N PF00618.20 PRP83167.1 - 2.2e-13 50.4 0.0 1e-12 48.2 0.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif zf-B_box PF00643.24 PRP83167.1 - 4.3e-07 30.0 6.2 1e-06 28.7 6.2 1.6 1 0 0 1 1 1 1 B-box zinc finger DUF2986 PF11661.8 PRP83167.1 - 0.0068 16.9 2.8 0.032 14.8 2.8 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) zf-MYND PF01753.18 PRP83167.1 - 3.5 7.8 9.8 7.2 6.8 9.8 1.5 1 0 0 1 1 1 0 MYND finger FA_hydroxylase PF04116.13 PRP83168.1 - 3.2e-24 85.8 21.2 5.1e-24 85.1 18.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily KTI12 PF08433.10 PRP83169.1 - 3.2e-83 279.3 0.0 3.6e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 PRP83169.1 - 2.4e-11 44.0 0.0 4.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 PRP83169.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Homeodomain PF00046.29 PRP83170.1 - 7.6e-23 80.1 12.9 1.5e-07 31.1 1.3 4.9 5 0 0 5 5 5 4 Homeodomain Homeobox_KN PF05920.11 PRP83170.1 - 1.7e-10 40.7 12.2 0.017 15.0 0.8 4.9 5 0 0 5 5 5 4 Homeobox KN domain Homez PF11569.8 PRP83170.1 - 0.00021 20.7 4.6 0.081 12.4 0.0 3.9 4 0 0 4 4 4 2 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 PRP83170.1 - 0.012 15.4 1.1 21 5.1 0.1 3.8 4 0 0 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR_1 PF13411.6 PRP83170.1 - 0.049 13.7 3.0 28 4.9 0.3 4.2 5 0 0 5 5 5 0 MerR HTH family regulatory protein BUD22 PF09073.10 PRP83170.1 - 0.15 11.4 26.1 0.25 10.7 11.6 2.2 2 0 0 2 2 2 0 BUD22 MSP1a PF11670.8 PRP83170.1 - 0.34 10.2 1.9 0.78 9.0 1.9 1.6 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Ank_2 PF12796.7 PRP83171.1 - 1.9e-14 54.0 0.0 6e-07 30.0 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP83171.1 - 2.4e-11 43.9 4.8 5.5e-05 23.6 0.0 4.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP83171.1 - 2.5e-09 37.2 2.2 0.56 10.7 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PRP83171.1 - 3.1e-07 30.5 1.0 4.6 7.7 0.0 4.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP83171.1 - 1.7e-05 24.8 0.2 0.96 10.2 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat TIL PF01826.17 PRP83171.1 - 0.0061 16.8 5.4 0.0061 16.8 5.4 1.9 2 0 0 2 2 2 1 Trypsin Inhibitor like cysteine rich domain DBC1 PF14443.6 PRP83171.1 - 0.015 15.3 1.3 4.1 7.4 0.0 3.2 3 0 0 3 3 3 0 DBC1 DUF1110 PF06533.12 PRP83171.1 - 0.073 13.0 0.5 3.5 7.6 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1110) RhoGAP PF00620.27 PRP83172.1 - 1.8e-06 27.8 0.1 3.4e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain EGF_2 PF07974.13 PRP83174.1 - 0.025 14.9 7.5 0.025 14.9 7.5 2.5 2 0 0 2 2 2 0 EGF-like domain Na_K-ATPase PF00287.18 PRP83174.1 - 0.23 10.6 4.4 0.96 8.6 2.6 2.6 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain SH3_9 PF14604.6 PRP83175.1 - 2e-13 50.0 0.0 3.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP83175.1 - 1.3e-11 44.0 0.0 2.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP83175.1 - 2.2e-08 33.6 0.0 4.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BUD22 PF09073.10 PRP83175.1 - 0.0024 17.3 14.5 0.0032 16.9 14.5 1.2 1 0 0 1 1 1 1 BUD22 RR_TM4-6 PF06459.12 PRP83175.1 - 0.0042 16.9 12.9 0.0042 16.9 12.9 1.9 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 VSG_B PF13206.6 PRP83175.1 - 0.0068 15.7 11.1 0.0068 15.7 11.1 1.6 2 0 0 2 2 2 1 Trypanosomal VSG domain EMC3_TMCO1 PF01956.16 PRP83175.1 - 0.021 14.6 5.2 2.3 7.9 4.5 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like GOLD_2 PF13897.6 PRP83175.1 - 0.024 15.1 5.5 0.092 13.2 2.8 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking CENP-N PF05238.13 PRP83175.1 - 0.038 13.3 6.1 0.06 12.7 6.1 1.3 1 1 0 1 1 1 0 Kinetochore protein CHL4 like DUF1764 PF08576.10 PRP83175.1 - 0.043 14.7 15.3 0.043 14.7 15.3 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SprA-related PF12118.8 PRP83175.1 - 0.048 12.8 9.7 0.084 12.0 9.7 1.3 1 0 0 1 1 1 0 SprA-related family Peptidase_U57 PF05582.12 PRP83175.1 - 0.05 12.9 5.8 0.089 12.0 5.8 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Zip PF02535.22 PRP83175.1 - 0.055 12.7 2.3 0.073 12.3 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 PRP83175.1 - 0.057 13.6 11.7 0.063 13.5 8.3 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4770 PF15994.5 PRP83175.1 - 0.11 12.7 4.8 0.23 11.7 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Neur_chan_memb PF02932.16 PRP83175.1 - 0.12 12.4 2.3 0.19 11.7 2.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 PRP83175.1 - 0.13 10.3 3.3 0.18 9.9 3.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_Ag35 PF03286.14 PRP83175.1 - 0.26 11.0 18.0 0.32 10.7 12.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2052 PF09747.9 PRP83175.1 - 0.32 11.1 15.8 0.46 10.6 12.9 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) EOS1 PF12326.8 PRP83175.1 - 0.39 10.6 1.0 0.41 10.5 0.2 1.6 2 0 0 2 2 1 0 N-glycosylation protein TCP PF03634.13 PRP83175.1 - 0.41 11.2 12.6 0.17 12.4 9.6 1.8 2 0 0 2 2 2 0 TCP family transcription factor LMBR1 PF04791.16 PRP83175.1 - 0.49 9.2 1.4 0.53 9.1 1.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FRG1 PF06229.12 PRP83175.1 - 0.5 10.0 12.6 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 FRG1-like domain NARP1 PF12569.8 PRP83175.1 - 0.62 8.9 19.6 0.64 8.9 16.7 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RNA_pol_Rpc4 PF05132.14 PRP83175.1 - 0.64 10.4 13.5 0.094 13.1 9.1 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF2828 PF11443.8 PRP83175.1 - 0.73 7.8 10.4 1.1 7.2 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PTPRCAP PF15713.5 PRP83175.1 - 0.95 9.7 17.7 0.72 10.1 13.6 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Roughex PF06020.11 PRP83175.1 - 0.97 8.5 9.8 1.7 7.6 9.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein ALMT PF11744.8 PRP83175.1 - 1.2 7.9 5.6 2 7.2 5.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter TP53IP5 PF15331.6 PRP83175.1 - 1.2 9.2 10.9 0.14 12.3 6.7 1.7 2 0 0 2 2 1 0 Cellular tumour antigen p53-inducible 5 Afi1 PF07792.12 PRP83175.1 - 1.2 9.6 12.6 0.5 10.8 8.9 1.9 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EIIBC-GUT_N PF03612.14 PRP83175.1 - 1.4 8.6 10.9 0.3 10.8 6.5 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Rxt3 PF08642.10 PRP83175.1 - 1.5 9.6 5.4 1.7 9.4 3.0 2.1 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Vfa1 PF08432.10 PRP83175.1 - 1.6 9.1 20.3 0.17 12.2 15.0 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Membralin PF09746.9 PRP83175.1 - 1.6 7.6 3.6 2.7 6.9 3.6 1.4 1 0 0 1 1 1 0 Tumour-associated protein GAGA_bind PF06217.12 PRP83175.1 - 1.8 8.7 9.0 0.31 11.3 5.6 1.5 2 0 0 2 2 1 0 GAGA binding protein-like family DUF2058 PF09831.9 PRP83175.1 - 2.6 8.2 17.9 0.84 9.8 14.3 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) RPA43_OB PF17875.1 PRP83175.1 - 2.6 8.7 11.3 1.4 9.5 8.1 2.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I O-antigen_lig PF13425.6 PRP83175.1 - 3.2 6.4 11.8 5.6 5.6 11.8 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Tfb4 PF03850.14 PRP83175.1 - 3.2 7.2 4.5 5.4 6.4 4.5 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 VIR_N PF15912.5 PRP83175.1 - 3.8 7.0 14.2 0.38 10.3 9.8 1.5 2 0 0 2 2 1 0 Virilizer, N-terminal GRA6 PF05084.13 PRP83175.1 - 4.9 7.1 9.0 29 4.5 5.8 2.2 2 0 0 2 2 2 0 Granule antigen protein (GRA6) CLN3 PF02487.17 PRP83175.1 - 6.2 5.8 6.9 11 5.0 6.9 1.3 1 0 0 1 1 1 0 CLN3 protein Coilin_N PF15862.5 PRP83175.1 - 6.6 6.5 20.1 37 4.1 18.1 2.3 2 0 0 2 2 2 0 Coilin N-terminus CDC45 PF02724.14 PRP83175.1 - 8 4.6 15.1 2.4 6.3 12.3 1.5 2 0 0 2 2 2 0 CDC45-like protein Folate_carrier PF01770.18 PRP83175.1 - 8.2 5.0 5.0 14 4.3 5.0 1.3 1 0 0 1 1 1 0 Reduced folate carrier Eapp_C PF10238.9 PRP83175.1 - 9.1 6.3 12.6 2.5 8.1 9.0 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein Pannexin_like PF12534.8 PRP83175.1 - 9.3 5.2 6.7 17 4.3 6.7 1.4 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 TROVE PF05731.11 PRP83176.1 - 1.7e-89 300.9 7.5 2.5e-88 297.1 7.5 2.6 1 1 0 1 1 1 1 TROVE domain AMP-binding PF00501.28 PRP83176.1 - 9.3e-36 123.3 0.0 1.6e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP83176.1 - 2.5e-17 63.6 0.1 8.3e-17 61.9 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RVT_1 PF00078.27 PRP83178.1 - 7.1e-26 91.1 0.0 2.5e-14 53.4 0.0 3.5 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5486 PF17588.2 PRP83178.1 - 0.00038 20.3 6.0 0.77 9.7 0.3 3.9 3 0 0 3 3 3 2 Family of unknown function (DUF5486) PaREP1 PF05942.11 PRP83178.1 - 0.0077 16.2 11.4 4.3 7.3 0.2 4.3 4 0 0 4 4 4 3 Archaeal PaREP1/PaREP8 family Herpes_IE68 PF02479.16 PRP83178.1 - 0.024 14.2 0.3 45 3.6 0.0 3.6 3 0 0 3 3 3 0 Herpesvirus immediate early protein DUF4315 PF14193.6 PRP83178.1 - 0.46 10.5 19.7 4 7.5 2.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) Coatamer_beta_C PF07718.12 PRP83178.1 - 1.5 8.7 9.0 37 4.2 1.2 4.3 3 1 0 3 3 3 0 Coatomer beta C-terminal region Pox_A_type_inc PF04508.12 PRP83178.1 - 2.6 8.0 7.2 22 5.1 0.8 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF5113 PF17140.4 PRP83178.1 - 4.2 7.2 5.2 54 3.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) Ribosomal_L29e PF01779.17 PRP83178.1 - 4.3 7.7 23.6 5.9 7.3 0.8 5.3 4 3 1 5 5 5 0 Ribosomal L29e protein family DUF1248 PF06852.12 PRP83179.1 - 0.055 13.0 0.1 0.12 11.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1248) RNase_H PF00075.24 PRP83179.1 - 0.18 12.0 0.5 16 5.7 0.7 2.2 2 0 0 2 2 2 0 RNase H Prothymosin PF03247.14 PRP83182.1 - 0.0051 17.2 18.0 0.0067 16.9 18.0 1.2 1 0 0 1 1 1 1 Prothymosin/parathymosin family BSP_II PF05432.11 PRP83182.1 - 0.023 14.4 13.4 0.028 14.1 13.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TLP-20 PF06088.11 PRP83182.1 - 0.11 12.4 0.9 0.15 12.0 0.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) XRN_M PF17846.1 PRP83182.1 - 0.12 11.3 0.8 0.15 10.9 0.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Myc_N PF01056.18 PRP83182.1 - 0.23 11.4 2.9 0.25 11.2 2.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Paf1 PF03985.13 PRP83182.1 - 1.9 7.4 11.6 2.6 6.9 11.6 1.1 1 0 0 1 1 1 0 Paf1 Astro_capsid_p PF12226.8 PRP83182.1 - 2 7.5 10.9 2.2 7.3 10.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM176 PF14851.6 PRP83182.1 - 3 7.5 6.7 4.4 6.9 6.7 1.4 1 0 0 1 1 1 0 FAM176 family DUF4746 PF15928.5 PRP83182.1 - 3.2 7.1 7.2 3.7 6.9 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 PRP83182.1 - 3.7 5.6 13.3 4.2 5.5 13.3 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 PRP83182.1 - 5.6 6.2 13.2 6.7 5.9 13.2 1.1 1 0 0 1 1 1 0 NOA36 protein Pectate_lyase_3 PF12708.7 PRP83184.1 - 2.1e-41 142.2 5.9 3.6e-36 125.0 1.3 6.4 3 2 4 7 7 7 3 Pectate lyase superfamily protein Chlam_PMP PF02415.17 PRP83184.1 - 0.018 15.5 2.0 0.018 15.5 2.0 12.7 14 2 0 14 14 14 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Adeno_E1B_55K PF01696.17 PRP83184.1 - 1.8 7.2 7.9 0.42 9.2 2.2 2.8 2 1 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Pentapeptide_4 PF13599.6 PRP83184.1 - 6.3 7.0 9.0 5.4 7.3 0.4 4.7 5 0 0 5 5 5 0 Pentapeptide repeats (9 copies) Pkinase_Tyr PF07714.17 PRP83185.1 - 1.7e-32 112.7 2.5 2.5e-32 112.2 2.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83185.1 - 5.7e-31 107.8 4.5 8.2e-31 107.3 4.5 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP83185.1 - 9.2e-10 38.9 6.4 2e-09 37.8 6.4 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif B_lectin PF01453.24 PRP83185.1 - 5.6e-05 23.6 1.2 0.016 15.7 0.2 3.4 1 1 2 3 3 3 2 D-mannose binding lectin Kdo PF06293.14 PRP83185.1 - 0.098 12.0 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family D123 PF07065.14 PRP83186.1 - 8e-22 77.8 0.3 1e-20 74.1 0.3 2.3 1 1 0 1 1 1 1 D123 R2K_2 PF18299.1 PRP83186.1 - 1.1e-05 25.3 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 PRP83186.1 - 0.0026 17.8 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 WD40 PF00400.32 PRP83187.1 - 3.6e-16 59.2 9.7 1.5e-07 32.0 0.1 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 PRP83187.1 - 1.7e-08 33.8 2.7 0.0049 15.9 0.1 3.1 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein FAM176 PF14851.6 PRP83187.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Colicin_Ia PF11504.8 PRP83187.1 - 0.24 11.6 1.4 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Colicin Ia DUF3042 PF11240.8 PRP83187.1 - 0.44 10.6 5.2 1.9 8.6 5.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3042) Pkinase_Tyr PF07714.17 PRP83188.1 - 6.1e-67 225.6 0.0 1.4e-66 224.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83188.1 - 5.8e-49 166.8 0.0 1.1e-48 165.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP83188.1 - 0.00023 20.6 0.0 0.00045 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP83188.1 - 0.012 14.4 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PRP83188.1 - 0.014 14.4 0.4 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Amnionless PF14828.6 PRP83188.1 - 0.089 11.6 0.2 0.17 10.7 0.2 1.3 1 0 0 1 1 1 0 Amnionless ECSCR PF15820.5 PRP83188.1 - 0.21 11.4 4.6 0.85 9.5 4.6 2.0 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Protocadherin PF08374.11 PRP83188.1 - 0.37 10.7 1.3 0.83 9.6 1.3 1.5 1 0 0 1 1 1 0 Protocadherin TMEM154 PF15102.6 PRP83188.1 - 0.37 10.7 1.9 0.88 9.5 1.9 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 PRP83188.1 - 0.39 10.1 2.8 0.44 9.9 0.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Aldo_ket_red PF00248.21 PRP83189.1 - 3.6e-50 170.8 0.0 4.6e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_membrane PF00664.23 PRP83190.1 - 3.1e-109 364.9 25.2 5.1e-59 200.2 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP83190.1 - 2.4e-70 235.4 0.1 9.1e-35 120.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PRP83190.1 - 3e-17 62.8 0.0 5.6e-07 29.2 0.0 4.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PRP83190.1 - 5.2e-09 36.7 4.4 8.6e-05 23.0 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 PRP83190.1 - 4.6e-08 32.3 0.2 0.001 18.0 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 PRP83190.1 - 1.5e-07 31.8 2.6 0.0032 17.7 0.2 3.7 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 PRP83190.1 - 8.6e-06 25.6 2.5 0.029 14.1 0.4 3.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PRP83190.1 - 2.4e-05 24.0 2.0 0.031 14.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PRP83190.1 - 9.9e-05 22.3 0.1 0.48 10.3 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase SbcCD_C PF13558.6 PRP83190.1 - 0.00018 21.7 4.0 0.54 10.5 0.5 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 PRP83190.1 - 0.00031 20.1 2.5 0.18 11.1 0.0 3.4 4 0 0 4 4 4 2 Zeta toxin AAA_33 PF13671.6 PRP83190.1 - 0.0019 18.4 0.0 3 8.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 PRP83190.1 - 0.0021 18.0 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain APS_kinase PF01583.20 PRP83190.1 - 0.0026 17.7 0.1 0.56 10.1 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_7 PF12775.7 PRP83190.1 - 0.011 15.3 0.0 5 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 PRP83190.1 - 0.013 15.9 7.6 1.1 9.7 0.7 4.4 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 PRP83190.1 - 0.015 14.9 0.1 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 PRP83190.1 - 0.016 15.2 0.9 6.8 6.7 0.0 4.3 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 PRP83190.1 - 0.029 14.6 2.1 7.3 6.8 0.2 3.4 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 PRP83190.1 - 0.039 13.7 0.0 14 5.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain GHMP_kinases_C PF08544.13 PRP83190.1 - 0.14 12.6 0.1 0.44 10.9 0.1 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal RNA_helicase PF00910.22 PRP83190.1 - 0.16 12.4 0.1 17 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 PRP83190.1 - 0.18 11.5 3.4 27 4.5 0.1 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_25 PF13481.6 PRP83190.1 - 0.24 10.9 1.2 26 4.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain Usp PF00582.26 PRP83190.1 - 0.25 11.9 6.6 3.1 8.3 2.9 2.8 2 0 0 2 2 2 0 Universal stress protein family DUF2852 PF11014.8 PRP83190.1 - 0.27 11.4 1.6 8.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) AAA_23 PF13476.6 PRP83190.1 - 0.34 11.4 5.5 4.2 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain SnoaL_2 PF12680.7 PRP83192.1 - 2e-05 25.1 0.0 2.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain CAAP1 PF15335.6 PRP83193.1 - 0.0006 20.3 0.0 23 5.6 0.0 5.4 6 0 0 6 6 6 1 Caspase activity and apoptosis inhibitor 1 Q_salvage PF10343.9 PRP83193.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family Mucin15 PF15672.5 PRP83193.1 - 0.19 11.2 0.8 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 DUF4796 PF16044.5 PRP83194.1 - 0.07 12.7 0.1 0.073 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) MORN PF02493.20 PRP83195.1 - 3.1e-25 86.5 31.2 1.6e-07 30.8 0.3 5.5 5 0 0 5 5 5 5 MORN repeat zf-CCHC PF00098.23 PRP83195.1 - 0.17 12.0 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Methyltransf_16 PF10294.9 PRP83196.1 - 4.2e-33 114.5 0.1 5.8e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 PRP83196.1 - 1.7e-09 37.5 0.1 2.6e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PRP83196.1 - 3.2e-07 30.3 0.0 4.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP83196.1 - 4.3e-06 26.7 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP83196.1 - 2.1e-05 25.1 0.0 4.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP83196.1 - 0.00031 21.4 0.0 0.00063 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 PRP83196.1 - 0.00065 18.9 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_11 PF08241.12 PRP83196.1 - 0.00086 19.9 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP83196.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 PRP83196.1 - 0.0032 17.3 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 PRP83196.1 - 0.0033 17.1 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.20 PRP83196.1 - 0.008 15.5 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 PRP83196.1 - 0.012 15.3 0.0 0.046 13.5 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF938) HMG_CoA_synt_C PF08540.10 PRP83196.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal ATP-synt_C PF00137.21 PRP83197.1 - 5.8e-35 119.4 31.5 1.9e-20 73.0 9.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF441 PF04284.13 PRP83197.1 - 0.0033 17.4 5.8 0.0033 17.4 5.8 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF441) DUF4577 PF15145.6 PRP83197.1 - 3.5 7.7 4.3 0.39 10.7 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Guanylate_cyc PF00211.20 PRP83198.1 - 6.5e-25 87.8 0.0 1.1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Spc7 PF08317.11 PRP83198.1 - 0.05 12.5 50.2 0.016 14.1 10.6 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein HrpA_pilin PF09589.10 PRP83198.1 - 1.4 9.7 6.1 0.43 11.3 1.8 2.4 2 0 0 2 2 2 0 HrpA pilus formation protein Exonuc_VII_L PF02601.15 PRP83198.1 - 3.9 7.0 31.5 0.24 10.9 10.5 2.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit Leu_zip PF15294.6 PRP83198.1 - 8 5.9 49.3 0.087 12.3 2.0 3.4 2 1 1 3 3 3 0 Leucine zipper RhoGEF PF00621.20 PRP83200.1 - 7.8e-32 111.0 2.0 7.8e-32 111.0 2.0 2.0 2 0 0 2 2 2 1 RhoGEF domain Ras PF00071.22 PRP83200.1 - 6.7e-11 42.0 0.0 1.5e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Ras family IQ_SEC7_PH PF16453.5 PRP83200.1 - 2.3e-06 27.6 0.1 2e-05 24.6 0.0 2.6 3 0 0 3 3 3 1 PH domain PH PF00169.29 PRP83200.1 - 0.00018 22.0 0.0 0.00056 20.4 0.0 1.8 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 PRP83200.1 - 0.0031 17.3 0.7 0.0085 15.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain BRF1 PF07741.13 PRP83200.1 - 9.3 6.7 8.7 0.32 11.3 1.1 2.5 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Guanylate_cyc PF00211.20 PRP83201.1 - 2.8e-26 92.3 0.0 5e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Mod_r PF07200.13 PRP83201.1 - 0.0012 19.0 0.6 0.0012 19.0 0.6 3.8 2 2 1 3 3 3 1 Modifier of rudimentary (Mod(r)) protein GIT_CC PF16559.5 PRP83201.1 - 0.0093 15.8 4.3 2.1 8.3 1.9 3.0 2 0 0 2 2 2 2 GIT coiled-coil Rho guanine nucleotide exchange factor PI3K_P85_iSH2 PF16454.5 PRP83201.1 - 2.2 7.9 24.9 0.027 14.1 2.8 3.2 2 1 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain bZIP_1 PF00170.21 PRP83201.1 - 3 8.0 14.2 1.3 9.1 2.2 3.8 3 0 0 3 3 3 0 bZIP transcription factor Cofilin_ADF PF00241.20 PRP83202.1 - 8.1e-24 83.8 0.2 1.3e-11 44.3 0.1 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4909 PF16253.5 PRP83202.1 - 0.024 14.5 0.0 0.062 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4909) Pkinase_Tyr PF07714.17 PRP83203.1 - 1.9e-70 237.1 0.0 2.6e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83203.1 - 1.9e-41 142.2 0.0 2.8e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WW PF00397.26 PRP83203.1 - 3.2e-23 81.5 3.1 7.5e-09 35.5 0.0 3.7 3 0 0 3 3 3 3 WW domain Kdo PF06293.14 PRP83203.1 - 0.00042 19.7 0.1 0.00077 18.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP83203.1 - 0.16 11.6 0.1 0.32 10.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family p53-inducible11 PF14936.6 PRP83204.1 - 7.2 6.6 7.1 10 6.1 0.3 3.1 2 1 1 3 3 3 0 Tumour protein p53-inducible protein 11 DUF5463 PF17551.2 PRP83205.1 - 0.1 12.5 0.5 0.16 11.9 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5463) MFS_1 PF07690.16 PRP83207.1 - 3.9e-38 131.3 28.2 3.9e-38 131.3 28.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 PRP83207.1 - 5.9e-06 25.0 2.6 1e-05 24.2 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2838 PF10998.8 PRP83208.1 - 1.3e-34 118.7 7.2 1.3e-34 118.7 7.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) HisKA PF00512.25 PRP83209.1 - 0.00078 19.4 0.1 0.0023 18.0 0.1 1.8 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 PRP83209.1 - 0.016 15.5 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 PRP83209.1 - 0.027 14.5 0.0 4.2 7.4 0.0 3.0 3 0 0 3 3 3 0 PAS fold PAS_9 PF13426.7 PRP83209.1 - 0.15 12.3 0.0 7.5 6.9 0.0 3.3 3 1 1 4 4 4 0 PAS domain AhpC-TSA PF00578.21 PRP83210.1 - 9.1e-34 116.1 0.0 1.1e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PRP83210.1 - 3.7e-15 55.9 0.0 4.4e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 PRP83210.1 - 0.018 15.3 0.0 0.025 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Melibiase_2 PF16499.5 PRP83211.1 - 2.4e-29 102.4 0.9 7.5e-15 54.8 0.1 2.4 2 0 0 2 2 2 2 Alpha galactosidase A Bromodomain PF00439.25 PRP83211.1 - 3.1e-17 62.4 0.0 6.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Melibiase_C PF17801.1 PRP83211.1 - 1.2e-14 54.1 0.1 2.9e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 PRP83211.1 - 1.8e-07 30.5 0.0 4.2e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Melibiase Ank_2 PF12796.7 PRP83211.1 - 5.9e-05 23.6 0.0 0.00015 22.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-4CXXC_R1 PF10497.9 PRP83211.1 - 0.00097 19.3 17.9 0.00097 19.3 17.9 2.0 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Ank_3 PF13606.6 PRP83211.1 - 0.025 15.1 0.0 0.44 11.3 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 PRP83211.1 - 0.042 14.2 0.0 0.23 11.8 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Glyco_hydro_97 PF10566.9 PRP83211.1 - 0.12 11.6 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Glycoside hydrolase 97 Sod_Cu PF00080.20 PRP83212.1 - 6.7e-55 185.2 11.3 5.9e-28 97.8 2.4 2.9 3 0 0 3 3 3 2 Copper/zinc superoxide dismutase (SODC) Ras PF00071.22 PRP83212.1 - 4.8e-54 182.3 0.2 9.5e-54 181.4 0.2 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP83212.1 - 2e-31 108.7 0.0 4.8e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP83212.1 - 1.3e-13 50.8 0.1 2.1e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP83212.1 - 0.00045 19.8 0.1 0.0012 18.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP83212.1 - 0.0018 18.3 0.1 0.0038 17.3 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP83212.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 PRP83212.1 - 0.0049 16.4 1.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 PRP83212.1 - 0.027 14.8 0.0 0.084 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PRP83212.1 - 0.035 14.0 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 PRP83212.1 - 0.051 13.3 0.3 0.18 11.5 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 PRP83212.1 - 0.088 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 PRP83212.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain F-box-like PF12937.7 PRP83213.1 - 3.3e-09 36.5 1.6 5.7e-09 35.7 1.6 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP83213.1 - 0.00096 19.0 1.7 0.002 18.0 1.7 1.6 1 0 0 1 1 1 1 F-box domain DUF896 PF05979.12 PRP83213.1 - 0.48 10.3 3.1 2.3 8.1 1.0 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF896) NAD_Gly3P_dh_N PF01210.23 PRP83214.1 - 6.1e-51 172.5 0.2 1.2e-50 171.6 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 PRP83214.1 - 1.3e-47 161.6 0.0 2.3e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 PRP83214.1 - 0.0044 17.6 0.9 0.071 13.7 0.9 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Claudin_3 PF06653.11 PRP83215.1 - 5.6e-05 23.1 8.0 0.0006 19.8 3.2 2.4 2 0 0 2 2 2 2 Tight junction protein, Claudin-like CD20 PF04103.15 PRP83215.1 - 0.014 15.5 8.6 0.057 13.5 3.6 3.1 3 0 0 3 3 3 0 CD20-like family DUF4231 PF14015.6 PRP83215.1 - 1.6 9.3 4.6 6.7 7.2 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF4807 PF16065.5 PRP83216.1 - 4e-12 45.9 0.0 6.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4807) GSH-S_ATP PF02955.16 PRP83216.1 - 0.007 15.8 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain Glyco_trans_1_4 PF13692.6 PRP83220.1 - 1.1e-11 45.3 0.0 2.5e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PRP83220.1 - 3.9e-11 42.8 0.0 1.7e-10 40.7 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PRP83220.1 - 0.00092 19.6 0.0 0.005 17.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 LEA_4 PF02987.16 PRP83221.1 - 1.8e-06 27.9 44.5 0.0081 16.2 4.6 4.5 1 1 3 4 4 4 4 Late embryogenesis abundant protein DUF4486 PF14858.6 PRP83221.1 - 0.08 11.4 0.7 0.16 10.4 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) Bactofilin PF04519.13 PRP83221.1 - 1.2 9.5 17.1 0.95 9.8 8.7 3.1 1 1 2 3 3 3 0 Polymer-forming cytoskeletal DUF1103 PF06513.11 PRP83221.1 - 1.4 8.5 19.1 4.9 6.7 11.5 2.0 1 1 0 1 1 1 0 Repeat of unknown function (DUF1103) Vps62 PF06101.11 PRP83222.1 - 0.00017 20.1 0.1 0.0021 16.4 0.0 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 RicinB_lectin_2 PF14200.6 PRP83222.1 - 0.001 19.7 2.4 0.11 13.2 0.0 3.9 4 0 0 4 4 4 1 Ricin-type beta-trefoil lectin domain-like SAP PF02037.27 PRP83223.1 - 1e-07 31.5 0.2 1.6e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 SAP domain dsDNA_bind PF01984.20 PRP83223.1 - 0.024 14.9 0.2 0.057 13.7 0.1 1.7 1 1 0 1 1 1 0 Double-stranded DNA-binding domain RNA_pol_Rpb4 PF03874.16 PRP83224.1 - 1.1e-18 67.7 0.6 1.4e-18 67.4 0.6 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 UBA_e1_thiolCys PF10585.9 PRP83225.1 - 2.9e-15 56.9 0.1 6.2e-15 55.8 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-activating enzyme active site DUF3584 PF12128.8 PRP83226.1 - 0.00049 17.8 19.3 0.00055 17.6 19.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) OmpH PF03938.14 PRP83226.1 - 0.014 15.8 16.9 0.014 15.8 16.9 2.6 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) FAM184 PF15665.5 PRP83226.1 - 0.052 13.3 30.9 0.13 12.1 17.4 2.5 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF5595 PF18077.1 PRP83226.1 - 0.13 12.4 20.3 0.51 10.5 1.1 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF5595) SHE3 PF17078.5 PRP83226.1 - 0.16 11.7 33.4 0.23 11.1 14.9 2.4 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Tup_N PF08581.10 PRP83226.1 - 0.2 12.0 22.4 1.5 9.2 3.4 3.9 1 1 2 3 3 3 0 Tup N-terminal CdvA PF18822.1 PRP83226.1 - 0.31 10.9 26.8 0.083 12.7 8.8 3.4 1 1 2 3 3 3 0 CdvA-like coiled-coil domain Gp-FAR-1 PF05823.12 PRP83226.1 - 0.74 10.2 16.8 1.3 9.4 16.2 1.7 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) V_ATPase_I PF01496.19 PRP83226.1 - 0.81 7.5 15.4 0.99 7.2 15.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 PRP83226.1 - 2.8 6.7 10.6 3.4 6.5 10.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Bombinin PF05298.11 PRP83226.1 - 3.4 7.3 8.5 0.41 10.3 0.6 2.8 1 1 2 3 3 3 0 Bombinin YlqD PF11068.8 PRP83226.1 - 4.4 7.7 22.9 20 5.6 11.6 2.4 1 1 1 2 2 2 0 YlqD protein FlxA PF14282.6 PRP83226.1 - 4.5 7.3 21.4 0.61 10.1 10.9 2.4 1 1 1 2 2 2 0 FlxA-like protein M PF02370.16 PRP83226.1 - 5.4 7.9 18.1 2.7 8.9 0.5 5.8 4 2 1 5 5 5 0 M protein repeat FAM76 PF16046.5 PRP83226.1 - 6.5 6.0 21.3 10 5.4 21.3 1.3 1 0 0 1 1 1 0 FAM76 protein TPR_MLP1_2 PF07926.12 PRP83226.1 - 10 6.2 32.1 3.2 7.8 21.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Solute_trans_a PF03619.16 PRP83227.1 - 8.9e-90 300.8 22.7 1.1e-89 300.5 22.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PH PF00169.29 PRP83227.1 - 1.1e-14 54.8 0.1 2.6e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PRP83227.1 - 3.4e-06 27.3 0.0 6.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 PRP83227.1 - 7e-05 22.9 0.1 0.00015 21.8 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 PRP83227.1 - 0.009 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PRP83227.1 - 0.083 13.3 1.2 2.5 8.5 1.2 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain SH2 PF00017.24 PRP83228.1 - 3.8e-21 75.0 0.0 6.3e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP83228.1 - 1.3e-09 38.6 0.0 2.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2_2 PF14633.6 PRP83228.1 - 0.0058 16.1 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 2 SH2 domain RhoGEF PF00621.20 PRP83231.1 - 9e-30 104.3 2.6 4.1e-29 102.1 1.4 2.4 2 0 0 2 2 2 1 RhoGEF domain DUF5102 PF17104.5 PRP83231.1 - 0.0024 18.0 3.9 0.0024 18.0 3.9 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF5102) SPATA1_C PF15743.5 PRP83231.1 - 1.1 9.3 4.8 4 7.5 1.8 2.5 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Pkinase PF00069.25 PRP83232.1 - 1.2e-27 96.9 0.0 2.9e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83232.1 - 1.2e-13 50.9 0.0 2.5e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DSPc PF00782.20 PRP83232.1 - 0.00074 19.3 0.0 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Vfa1 PF08432.10 PRP83232.1 - 0.035 14.4 0.4 0.035 14.4 0.4 2.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 PRP83232.1 - 0.67 10.4 6.1 3.2 8.2 0.4 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 IFT81_CH PF18383.1 PRP83233.1 - 9.5e-35 119.5 0.2 9.5e-35 119.5 0.2 2.8 4 0 0 4 4 4 1 Intraflagellar transport 81 calponin homology domain IFT57 PF10498.9 PRP83233.1 - 0.0042 16.1 11.1 0.0042 16.1 11.1 4.0 2 1 1 4 4 4 2 Intra-flagellar transport protein 57 Tup_N PF08581.10 PRP83233.1 - 0.017 15.4 3.0 0.017 15.4 3.0 6.2 4 3 1 5 5 5 0 Tup N-terminal Gemini_V2 PF01524.17 PRP83233.1 - 0.12 12.6 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 Geminivirus V2 protein DUF3037 PF11236.8 PRP83233.1 - 1.5 9.3 11.2 5.3 7.5 0.0 4.8 2 1 1 4 4 4 0 Protein of unknown function (DUF3037) Cupin_8 PF13621.6 PRP83234.1 - 4.9e-37 128.0 3.6 1.8e-36 126.1 1.4 2.1 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.22 PRP83234.1 - 0.019 15.4 1.6 0.03 14.8 0.1 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_4 PF08007.12 PRP83234.1 - 0.033 13.6 0.0 0.096 12.1 0.0 1.7 1 1 0 1 1 1 0 Cupin superfamily protein adh_short PF00106.25 PRP83235.1 - 4.9e-33 114.2 0.0 6.2e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP83235.1 - 7.9e-24 84.5 0.0 9.7e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP83235.1 - 5e-06 26.5 0.0 7.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF3782 PF12644.7 PRP83235.1 - 0.077 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) rve PF00665.26 PRP83237.1 - 0.0076 16.4 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain INTS5_N PF14837.6 PRP83237.1 - 0.015 14.9 1.2 0.33 10.5 0.1 2.4 1 1 1 2 2 2 0 Integrator complex subunit 5 N-terminus DUF1948 PF09185.10 PRP83240.1 - 0.069 13.0 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Curto_V3 PF07436.11 PRP83241.1 - 0.074 13.4 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Curtovirus V3 protein Trs65 PF12735.7 PRP83241.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 zf-C3HC4_3 PF13920.6 PRP83242.1 - 0.0033 17.2 12.2 0.03 14.2 8.5 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP83242.1 - 0.01 15.8 6.6 0.01 15.8 6.6 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PRP83242.1 - 0.014 15.2 0.8 0.014 15.2 0.8 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 PRP83242.1 - 0.022 14.8 7.1 0.089 12.8 7.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon HNH_2 PF13391.6 PRP83244.1 - 0.0097 16.0 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Telomere_Sde2_2 PF13297.6 PRP83245.1 - 2e-22 78.6 0.5 3.9e-22 77.6 0.5 1.5 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 PRP83245.1 - 1.9e-20 73.3 9.5 1.9e-20 73.3 9.5 3.1 2 2 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain FliO PF04347.13 PRP83245.1 - 0.09 13.1 0.7 1.3 9.3 0.0 2.9 2 0 0 2 2 2 0 Flagellar biosynthesis protein, FliO CARD PF00619.21 PRP83245.1 - 7.7 6.6 8.7 0.2 11.7 0.4 2.5 3 0 0 3 3 3 0 Caspase recruitment domain DUF3253 PF11625.8 PRP83246.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) BING4CT PF08149.11 PRP83246.1 - 0.05 13.4 0.0 3.7 7.4 0.0 2.2 1 1 1 2 2 2 0 BING4CT (NUC141) domain Pkinase PF00069.25 PRP83248.1 - 2.5e-08 33.6 0.0 4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP83248.1 - 1.6e-06 27.1 0.1 0.046 12.5 0.0 2.5 3 0 0 3 3 3 2 Fungal protein kinase APH PF01636.23 PRP83248.1 - 1.1e-05 25.5 0.4 0.00025 21.1 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP83248.1 - 1.9e-05 24.3 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family DUF4135 PF13575.6 PRP83248.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DDE_Tnp_4 PF13359.6 PRP83249.1 - 2.1e-09 37.2 0.0 4.1e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP83249.1 - 0.00032 20.4 0.1 0.0016 18.1 0.1 1.9 2 0 0 2 2 2 1 Transposase DDE domain N_NLPC_P60 PF12912.7 PRP83250.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term Kinesin PF00225.23 PRP83251.1 - 1.3e-95 320.2 0.6 1.3e-95 320.2 0.6 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP83251.1 - 1.5e-18 67.1 0.0 2.2e-14 53.7 0.0 3.0 2 0 0 2 2 2 2 Microtubule binding MKLP1_Arf_bdg PF16540.5 PRP83251.1 - 0.02 14.9 0.8 0.062 13.4 0.0 2.2 2 0 0 2 2 2 0 Arf6-interacting domain of mitotic kinesin-like protein 1 HAUS-augmin3 PF14932.6 PRP83251.1 - 0.19 11.2 17.8 0.46 10.0 17.8 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2408 PF10303.9 PRP83251.1 - 1.9 9.1 16.4 0.51 10.9 12.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) ECM11 PF15463.6 PRP83251.1 - 3 8.4 19.4 0.17 12.5 12.8 2.2 2 0 0 2 2 2 0 Extracellular mutant protein 11 Chisel PF15355.6 PRP83251.1 - 3.8 7.8 8.6 8.7 6.7 0.2 4.0 4 0 0 4 4 4 0 Stretch-responsive small skeletal muscle X protein, Chisel YabA PF06156.13 PRP83251.1 - 4.1 8.1 21.3 3.4 8.4 5.6 4.2 2 1 1 3 3 3 0 Initiation control protein YabA AFG1_ATPase PF03969.16 PRP83252.1 - 4.9e-100 334.9 0.6 5.8e-99 331.4 0.6 1.9 1 1 0 1 1 1 1 AFG1-like ATPase Bac_DnaA PF00308.18 PRP83252.1 - 5.3e-06 26.4 0.2 0.00058 19.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_16 PF13191.6 PRP83252.1 - 9.2e-05 22.9 0.1 0.016 15.6 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 PRP83252.1 - 0.003 17.5 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 PRP83252.1 - 0.016 15.6 0.0 0.13 12.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 PRP83252.1 - 0.062 13.7 0.0 1.2 9.6 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_5 PF07728.14 PRP83252.1 - 0.062 13.3 0.0 0.27 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TBP PF00352.21 PRP83253.1 - 5.9e-41 138.3 0.0 7.4e-26 89.9 0.1 2.9 2 1 1 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) RPAP2_Rtr1 PF04181.13 PRP83253.1 - 3.1e-22 78.7 2.5 7.1e-22 77.5 2.5 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family Peptidase_C71 PF12386.8 PRP83253.1 - 0.094 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei EBP PF05241.12 PRP83254.1 - 1.3e-28 99.7 3.9 1.5e-28 99.4 3.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein PH PF00169.29 PRP83255.1 - 1.8e-14 54.1 0.1 3e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 PH domain CH PF00307.31 PRP83255.1 - 1e-11 45.0 0.0 9.3e-07 29.0 0.1 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain PH_8 PF15409.6 PRP83255.1 - 4.2e-05 23.7 0.0 0.00013 22.1 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PRP83255.1 - 0.00012 22.4 2.0 0.00074 19.9 0.8 2.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PRP83255.1 - 0.013 15.5 0.0 0.057 13.5 0.0 2.0 1 1 0 1 1 1 0 PH domain Lactamase_B_6 PF16661.5 PRP83256.1 - 4.4e-10 39.3 0.0 1.5e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 PRP83256.1 - 3.6e-07 30.4 0.0 1.8e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Beta_lactamase3 PF17030.5 PRP83256.1 - 9.6e-06 25.0 0.2 8.1e-05 22.0 0.1 2.6 3 0 0 3 3 3 1 Putative beta-lactamase-like family UCH PF00443.29 PRP83257.1 - 9.2e-52 176.1 1.2 3.3e-51 174.2 1.2 2.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PIP5K PF01504.18 PRP83257.1 - 3e-33 115.2 0.4 5.1e-24 85.0 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 PRP83257.1 - 5e-28 98.0 0.0 8.4e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UCH_1 PF13423.6 PRP83257.1 - 1e-20 74.6 5.0 1e-20 74.6 5.0 3.2 4 0 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase FYVE PF01363.21 PRP83257.1 - 3.3e-18 65.6 9.7 3.3e-18 65.6 9.7 4.5 3 1 0 3 3 3 1 FYVE zinc finger zf-UBP PF02148.19 PRP83257.1 - 4.8e-10 39.6 6.3 4.8e-10 39.6 6.3 5.0 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein AIF_C PF14721.6 PRP83257.1 - 0.1 13.0 0.2 0.6 10.5 0.1 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SepSecS PF05889.13 PRP83258.1 - 2.3e-134 448.0 0.0 2.9e-134 447.6 0.0 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 PRP83258.1 - 0.0064 15.8 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 PRP83258.1 - 0.009 14.8 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF3692 PF12469.8 PRP83258.1 - 0.016 15.4 0.0 1.6 8.9 0.0 2.7 2 1 0 2 2 2 0 CRISPR-associated protein NAD_Gly3P_dh_C PF07479.14 PRP83258.1 - 0.091 13.0 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pkinase_Tyr PF07714.17 PRP83259.1 - 2.2e-70 236.9 0.0 3e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83259.1 - 4.3e-62 209.9 0.0 6.2e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP83259.1 - 7.5e-05 22.8 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP83259.1 - 0.00049 19.2 0.1 0.019 13.9 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Phage_tail_NK PF16532.5 PRP83259.1 - 0.031 13.9 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Sf6-type phage tail needle knob or tip of some Caudovirales RIO1 PF01163.22 PRP83259.1 - 0.068 12.8 0.4 0.17 11.5 0.3 1.6 1 1 1 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 PRP83259.1 - 0.15 10.8 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase RalF_SCD PF18248.1 PRP83261.1 - 0.065 13.2 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 RalF C-terminal Sec-7 capping domain PPR_2 PF13041.6 PRP83262.1 - 1.3e-09 38.1 1.7 2.7e-07 30.6 0.5 3.2 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 PRP83262.1 - 1.8e-07 31.1 4.1 0.008 16.2 0.1 4.2 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP83262.1 - 0.0005 19.5 0.8 0.2 11.0 0.2 3.3 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP83262.1 - 0.0043 16.7 0.2 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 PPR repeat PPR PF01535.20 PRP83262.1 - 0.033 14.4 1.5 0.16 12.2 0.1 3.0 3 0 0 3 3 3 0 PPR repeat Clathrin PF00637.20 PRP83262.1 - 1.8 8.4 7.6 16 5.4 0.1 4.2 3 2 1 4 4 4 0 Region in Clathrin and VPS HSP90 PF00183.18 PRP83263.1 - 9.2e-231 767.2 31.6 1.2e-230 766.8 31.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PRP83263.1 - 1.4e-13 51.3 0.1 3.2e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PRP83263.1 - 1.7e-11 44.1 0.1 6.1e-11 42.3 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase C2 PF00168.30 PRP83266.1 - 6.1e-20 71.4 0.0 1.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain GRAM PF02893.20 PRP83266.1 - 4.3e-15 55.6 0.2 3.1e-13 49.6 0.0 2.8 2 0 0 2 2 2 1 GRAM domain PIN_11 PF18479.1 PRP83267.1 - 0.0022 18.2 1.1 0.0036 17.4 0.1 1.9 2 0 0 2 2 2 1 PIN like domain DNA_pol3_a_NI PF14480.6 PRP83267.1 - 0.094 12.7 0.2 0.54 10.3 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I zf-CCCH_4 PF18044.1 PRP83267.1 - 0.25 11.2 6.7 0.52 10.2 2.0 2.7 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 PRP83267.1 - 0.66 10.0 12.7 0.039 13.9 1.8 3.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PRP83267.1 - 3.6 8.2 9.2 2.1 9.0 0.9 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 PRP83267.1 - 8 6.7 8.1 4.8 7.4 1.2 3.1 2 0 0 2 2 2 0 Zinc finger domain adh_short PF00106.25 PRP83269.1 - 1.4e-23 83.3 0.0 1.8e-22 79.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP83269.1 - 8.6e-16 58.2 0.0 3e-15 56.4 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Tetraspanin PF00335.20 PRP83269.1 - 4.2e-05 23.4 8.3 4.2e-05 23.4 8.3 1.7 1 1 0 1 1 1 1 Tetraspanin family KR PF08659.10 PRP83269.1 - 4.6e-05 23.4 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP83269.1 - 0.0029 17.1 0.2 0.01 15.3 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CD20 PF04103.15 PRP83269.1 - 0.0067 16.5 9.0 0.024 14.7 9.0 2.0 1 1 0 1 1 1 1 CD20-like family LPG_synthase_TM PF03706.13 PRP83269.1 - 0.033 13.7 2.9 0.06 12.9 2.9 1.4 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Vma12 PF11712.8 PRP83269.1 - 0.076 13.1 0.7 19 5.3 0.5 3.0 4 0 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase GDP_Man_Dehyd PF16363.5 PRP83269.1 - 0.15 11.4 0.7 0.75 9.1 0.7 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase HisKA PF00512.25 PRP83271.1 - 4.1e-14 52.3 0.1 1.6e-13 50.5 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 PRP83271.1 - 1.1e-13 51.6 0.1 2.1e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MASE3 PF17159.4 PRP83271.1 - 2.6e-09 37.1 23.1 6.5e-09 35.7 20.9 2.2 1 1 1 2 2 2 1 Membrane-associated sensor domain DUF4704 PF15787.5 PRP83271.1 - 0.032 13.5 0.1 0.069 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) DUF3054 PF11255.8 PRP83271.1 - 1 9.9 10.8 1.7 9.2 8.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3054) UvrD-helicase PF00580.21 PRP83272.1 - 7.1e-57 193.3 1.9 7.1e-57 193.3 1.9 1.6 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 PRP83272.1 - 6.9e-31 107.6 0.1 1.8e-30 106.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 PRP83272.1 - 1e-16 61.3 1.4 3.4e-13 49.7 0.0 2.9 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 PRP83272.1 - 7.5e-11 42.1 0.0 2e-07 30.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 PRP83272.1 - 5.6e-05 23.0 2.4 5.6e-05 23.0 2.4 2.7 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 PRP83272.1 - 0.001 18.9 0.1 0.2 11.4 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Terminase_6 PF03237.15 PRP83272.1 - 0.0056 16.4 1.1 0.5 10.0 0.0 2.6 2 1 1 3 3 3 1 Terminase-like family ResIII PF04851.15 PRP83272.1 - 0.046 13.7 2.3 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 PRP83272.1 - 0.067 13.0 0.1 0.21 11.4 0.1 2.0 1 1 0 1 1 1 0 Helicase Scaffolding_pro PF11418.8 PRP83272.1 - 1.8 9.2 5.4 0.88 10.2 2.3 2.1 2 0 0 2 2 2 0 Phi29 scaffolding protein SapB_2 PF03489.17 PRP83275.1 - 5.1e-05 23.3 0.3 0.00018 21.6 0.2 2.0 2 0 0 2 2 2 1 Saposin-like type B, region 2 Y_phosphatase3 PF13350.6 PRP83276.1 - 7.9e-45 153.6 0.2 7.2e-43 147.2 0.2 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 PRP83276.1 - 2e-08 34.0 0.0 4.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 PRP83276.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 PRP83276.1 - 0.0048 15.9 0.0 0.0095 14.9 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PHC2_SAM_assoc PF16616.5 PRP83276.1 - 0.036 14.9 3.6 0.09 13.6 3.6 1.6 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DSPc PF00782.20 PRP83276.1 - 0.091 12.6 0.1 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Pkinase_Tyr PF07714.17 PRP83277.1 - 3.4e-26 92.1 0.1 1.3e-25 90.2 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase DAP3 PF10236.9 PRP83277.1 - 4.6e-24 85.1 0.0 1.4e-23 83.6 0.0 1.8 1 1 1 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Pkinase PF00069.25 PRP83277.1 - 7.8e-19 68.0 0.0 1.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP83277.1 - 3.5e-06 27.4 11.1 4e-06 27.3 9.4 2.1 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif TMEM154 PF15102.6 PRP83277.1 - 0.00042 20.2 0.3 0.0015 18.4 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 PRP83277.1 - 0.01 15.7 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF5305 PF17231.2 PRP83277.1 - 0.087 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) PspB PF06667.12 PRP83277.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B RIFIN PF02009.16 PRP83277.1 - 0.18 11.7 0.3 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Rifin Ank_2 PF12796.7 PRP83278.1 - 5.9e-41 139.0 0.0 8.8e-14 51.9 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP83278.1 - 2.6e-31 107.6 0.0 5.5e-07 30.0 0.0 6.0 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 PRP83278.1 - 3e-23 81.2 0.0 0.00049 20.4 0.0 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 PRP83278.1 - 2.3e-21 75.5 0.0 2.8e-07 30.7 0.0 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP83278.1 - 2.5e-19 67.3 0.0 0.015 15.8 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeat DcpS_C PF11969.8 PRP83279.1 - 1e-17 64.7 0.1 1.4e-17 64.2 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 PRP83279.1 - 7e-13 49.2 0.2 1.2e-12 48.4 0.2 1.3 1 0 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 PRP83279.1 - 1e-06 28.6 1.1 1e-06 28.6 0.3 1.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Pribosyltran PF00156.27 PRP83280.1 - 3.2e-09 36.5 0.1 4.3e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 PRP83280.1 - 0.029 13.9 0.0 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Phosphoribosyl transferase Invasin_D3 PF09134.10 PRP83280.1 - 0.06 13.7 0.0 0.098 13.0 0.0 1.4 1 0 0 1 1 1 0 Invasin, domain 3 Myb_DNA-binding PF00249.31 PRP83281.1 - 3e-14 52.9 0.2 5.9e-14 52.0 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SCA7 PF08313.12 PRP83281.1 - 5.4e-05 23.0 0.1 0.00011 22.0 0.1 1.4 1 0 0 1 1 1 1 SCA7, zinc-binding domain Myb_DNA-bind_6 PF13921.6 PRP83281.1 - 0.00013 22.2 0.3 0.00023 21.3 0.3 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ank_2 PF12796.7 PRP83284.1 - 4.6e-24 84.8 0.7 4.7e-11 43.1 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP83284.1 - 3.9e-21 72.9 0.1 0.00024 21.3 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PRP83284.1 - 1.3e-20 73.1 0.1 2.3e-08 34.1 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP83284.1 - 4e-19 68.1 0.6 2.9e-05 24.3 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 PRP83284.1 - 5.6e-16 58.7 0.1 2.5e-08 34.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) bZIP_1 PF00170.21 PRP83284.1 - 0.13 12.4 3.4 1.1 9.4 3.0 2.7 1 1 1 2 2 2 0 bZIP transcription factor Ank_2 PF12796.7 PRP83285.1 - 3.3e-53 178.2 15.4 3e-17 63.0 0.3 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP83285.1 - 1.2e-40 137.0 17.1 1.8e-08 34.5 0.0 7.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP83285.1 - 3.5e-38 129.5 8.3 3.1e-14 53.1 0.1 6.3 1 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP83285.1 - 4.5e-32 106.5 3.0 0.00019 21.6 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 PRP83285.1 - 2.6e-31 106.7 12.2 0.00038 20.8 0.2 7.3 7 0 0 7 7 7 7 Ankyrin repeat CDC45 PF02724.14 PRP83285.1 - 0.036 12.4 26.4 0.049 11.9 26.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 PRP83285.1 - 4.6 6.0 16.7 6.5 5.5 16.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 PRP83285.1 - 8.4 5.3 18.4 12 4.8 18.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF4746 PF15928.5 PRP83285.1 - 8.8 5.7 26.5 14 5.0 26.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PP2C PF00481.21 PRP83286.1 - 3.2e-62 210.5 0.0 3.8e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP83286.1 - 0.002 18.1 0.0 0.0064 16.4 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) FAD_binding_1 PF00667.20 PRP83286.1 - 0.0083 15.7 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DUF3888 PF13027.6 PRP83286.1 - 0.074 13.5 0.1 0.21 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) Transposase_31 PF04754.12 PRP83286.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative transposase, YhgA-like RhoGEF PF00621.20 PRP83287.1 - 2.2e-40 138.8 3.1 7.6e-40 137.1 2.2 2.4 2 0 0 2 2 2 1 RhoGEF domain C2 PF00168.30 PRP83287.1 - 6e-12 45.8 0.1 2.5e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 C2 domain YhhN PF07947.14 PRP83287.1 - 1.2e-05 25.0 11.4 2.3e-05 24.1 11.4 1.4 1 0 0 1 1 1 1 YhhN family Arm PF00514.23 PRP83287.1 - 0.0012 18.8 7.0 12 6.2 0.2 6.7 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 PRP83287.1 - 0.0013 18.7 2.1 0.013 15.5 0.2 3.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 PRP83287.1 - 0.084 13.2 1.8 0.57 10.6 0.2 3.4 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 PRP83287.1 - 0.1 13.0 1.5 1.9 9.0 0.6 3.4 2 1 1 3 3 3 0 HEAT repeats cNMP_binding PF00027.29 PRP83288.1 - 3.7e-41 139.1 0.0 6.9e-21 74.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF5586 PF17824.1 PRP83288.1 - 7.1e-05 22.1 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5586) Cupin_2 PF07883.11 PRP83288.1 - 0.079 12.7 1.2 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Cupin domain RSB_motif PF16294.5 PRP83289.1 - 1.4e-14 54.2 5.2 1.4e-14 54.2 5.2 4.8 2 1 2 4 4 4 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 PRP83289.1 - 2.5e-12 46.3 1.1 5.4e-12 45.2 1.1 1.6 1 0 0 1 1 1 1 SAP domain Con-6 PF10346.9 PRP83289.1 - 9.6e-09 35.1 1.0 9.6e-09 35.1 1.0 2.8 4 0 0 4 4 4 1 Conidiation protein 6 DUF1612 PF07756.12 PRP83289.1 - 0.00046 20.4 0.2 0.036 14.3 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1612) Skp1_POZ PF03931.15 PRP83289.1 - 0.037 14.2 0.1 0.072 13.3 0.1 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain WD40 PF00400.32 PRP83290.1 - 5.4e-08 33.4 7.4 9.8e-05 23.1 0.1 4.8 4 1 0 4 4 4 2 WD domain, G-beta repeat Sigma70_ner PF04546.13 PRP83290.1 - 0.0011 18.9 0.2 0.0018 18.2 0.2 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Med30 PF11315.8 PRP83290.1 - 0.06 13.5 2.5 0.32 11.2 1.2 2.1 1 1 1 2 2 2 0 Mediator complex subunit 30 F-box-like PF12937.7 PRP83290.1 - 0.095 12.6 0.8 0.31 11.0 0.4 2.0 2 0 0 2 2 2 0 F-box-like Pox_H7 PF04787.12 PRP83290.1 - 0.14 12.7 0.1 0.36 11.3 0.1 1.7 2 0 0 2 2 2 0 Late protein H7 CtIP_N PF10482.9 PRP83290.1 - 0.14 12.2 1.7 0.2 11.7 0.3 1.9 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Glyco_transf_24 PF18404.1 PRP83291.1 - 3.4e-145 482.4 4.0 1.5e-144 480.3 4.7 1.7 2 0 0 2 2 2 1 Glucosyltransferase 24 Pkinase_Tyr PF07714.17 PRP83291.1 - 1.3e-75 254.1 0.0 3.2e-67 226.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 PRP83291.1 - 4.6e-60 199.2 174.0 1.1e-07 31.4 6.2 24.8 12 7 12 27 27 27 19 Leucine rich repeat LRR_4 PF12799.7 PRP83291.1 - 1.3e-50 168.5 193.7 0.00024 21.4 3.1 30.1 11 8 29 41 41 41 28 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP83291.1 - 1.4e-48 165.5 0.0 8.6e-48 163.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Thioredoxin_14 PF18402.1 PRP83291.1 - 5e-48 164.3 2.1 6.1e-43 147.6 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 PRP83291.1 - 5.3e-36 124.3 0.7 1e-35 123.3 0.7 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 PRP83291.1 - 2.8e-32 112.4 2.2 2.9e-31 109.1 1.1 2.5 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 PRP83291.1 - 1.5e-27 95.9 0.0 3.2e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 PRP83291.1 - 1.4e-21 76.9 0.1 6.8e-21 74.6 0.1 2.2 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 PRP83291.1 - 1.6e-07 31.2 1.7 3.1e-07 30.2 0.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Haspin_kinase PF12330.8 PRP83291.1 - 0.0054 15.7 0.1 0.026 13.5 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Aurora-A_bind PF09041.10 PRP83291.1 - 0.0063 16.6 0.0 5.4 7.1 0.0 2.8 2 0 0 2 2 2 1 Aurora-A binding Adeno_E3_CR2 PF02439.15 PRP83291.1 - 0.012 15.3 1.1 0.024 14.4 1.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkinase_fungal PF17667.1 PRP83291.1 - 0.012 14.4 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 PRP83291.1 - 0.036 13.4 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 PRP83291.1 - 0.064 12.6 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRRNT_2 PF08263.12 PRP83291.1 - 0.074 13.4 1.8 18 5.7 0.1 3.1 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain SKG6 PF08693.10 PRP83291.1 - 0.099 12.1 7.0 0.22 11.0 7.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PRP83291.1 - 0.19 12.6 0.4 0.42 11.5 0.4 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 PRP83291.1 - 0.55 10.2 2.5 1.1 9.3 2.5 1.4 1 0 0 1 1 1 0 Syndecan domain Mid2 PF04478.12 PRP83291.1 - 0.58 10.0 2.0 2.1 8.2 0.6 2.3 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Dict-STAT-coil PF09267.10 PRP83291.1 - 1.1 9.6 5.5 3.3 8.1 0.2 3.6 3 0 0 3 3 2 0 Dictyostelium STAT, coiled coil Pkinase_Tyr PF07714.17 PRP83292.1 - 1.8e-67 227.4 0.0 2.7e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83292.1 - 2.7e-48 164.6 0.0 4.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP83292.1 - 8.6e-45 150.3 118.4 8.2e-06 25.5 8.8 17.3 7 5 5 17 17 17 13 Leucine rich repeat LRR_4 PF12799.7 PRP83292.1 - 1.3e-38 130.4 121.3 0.00018 21.8 6.5 20.9 7 5 17 26 26 26 18 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP83292.1 - 7e-06 25.9 97.8 5.5 7.9 0.1 25.6 25 4 0 25 25 21 2 Leucine Rich Repeat Haspin_kinase PF12330.8 PRP83292.1 - 0.0036 16.3 0.3 0.019 13.9 0.3 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Adeno_E3_CR2 PF02439.15 PRP83292.1 - 0.004 16.9 0.6 0.0071 16.1 0.6 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Pkinase_fungal PF17667.1 PRP83292.1 - 0.0059 15.4 0.1 0.0092 14.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP83292.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 PRP83292.1 - 0.024 14.0 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syndecan PF01034.20 PRP83292.1 - 0.17 11.8 1.4 0.33 10.9 1.4 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.10 PRP83292.1 - 0.32 10.4 4.2 0.62 9.5 4.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_6 PF13516.6 PRP83292.1 - 0.5 10.6 100.4 12 6.2 0.1 23.3 27 0 0 27 27 26 0 Leucine Rich repeat ubiquitin PF00240.23 PRP83293.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Darcynin PF17074.5 PRP83293.1 - 0.071 13.3 0.0 0.085 13.1 0.0 1.1 1 0 0 1 1 1 0 Darcynin, domain of unknown function PTR2 PF00854.21 PRP83295.1 - 4.9e-83 279.2 7.1 8.4e-83 278.4 7.1 1.3 1 0 0 1 1 1 1 POT family RhoGEF PF00621.20 PRP83295.1 - 5.2e-37 127.8 0.6 5.2e-37 127.8 0.6 1.9 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 PRP83295.1 - 7.4e-09 36.1 0.4 2.6e-08 34.3 0.4 1.9 1 0 0 1 1 1 1 PH domain Fascin PF06268.13 PRP83296.1 - 2.6e-06 27.6 0.1 0.004 17.4 0.1 2.4 1 1 1 2 2 2 2 Fascin domain DUF569 PF04601.13 PRP83296.1 - 2.3e-05 24.1 0.0 0.01 15.5 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF569) FRG1 PF06229.12 PRP83296.1 - 0.0002 21.1 0.0 0.0052 16.5 0.0 2.4 1 1 1 2 2 2 1 FRG1-like domain Pro-rich PF15240.6 PRP83296.1 - 0.023 15.0 29.3 0.035 14.4 29.3 1.3 1 0 0 1 1 1 0 Proline-rich TrfA PF07042.11 PRP83297.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 TrfA protein C2 PF00168.30 PRP83298.1 - 2.2e-19 69.6 0.1 3.5e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 C2 domain Pro-rich PF15240.6 PRP83298.1 - 0.0023 18.3 36.3 0.0032 17.8 36.3 1.3 1 0 0 1 1 1 1 Proline-rich XYPPX PF02162.17 PRP83298.1 - 0.3 10.9 152.9 0.071 12.9 17.1 8.7 7 2 0 7 7 7 0 XYPPX repeat (two copies) Acyl-CoA_dh_1 PF00441.24 PRP83299.1 - 2.2e-29 102.6 2.9 3.3e-29 102.0 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PRP83299.1 - 1.2e-13 51.7 0.2 2.2e-12 47.6 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PRP83299.1 - 4.6e-10 39.6 0.0 1.1e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SH2 PF00017.24 PRP83300.1 - 9.1e-14 51.3 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 SH2 domain DUF599 PF04654.12 PRP83300.1 - 0.09 12.2 0.8 0.15 11.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF599 SH2_2 PF14633.6 PRP83300.1 - 0.19 11.1 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Ank_4 PF13637.6 PRP83301.1 - 9.2e-13 48.4 0.1 3.2e-07 30.7 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP83301.1 - 2.4e-11 44.0 0.0 4.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP83301.1 - 2.8e-11 43.4 1.3 2.7e-07 30.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP83301.1 - 2.6e-10 39.6 0.0 1.8e-05 24.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PRP83301.1 - 6.8e-10 38.9 0.1 3.6e-07 30.3 0.2 3.3 3 0 0 3 3 3 1 Ankyrin repeat CENP-F_leu_zip PF10473.9 PRP83303.1 - 0.016 15.2 0.2 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Macro PF01661.21 PRP83304.1 - 9.7e-36 122.4 0.1 2.1e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 Macro domain RE_AccI PF09545.10 PRP83306.1 - 0.003 16.6 0.1 0.005 15.9 0.1 1.3 1 0 0 1 1 1 1 AccI restriction endonuclease ADP_ribosyl_GH PF03747.14 PRP83307.1 - 6.7e-25 88.4 0.0 1.4e-24 87.3 0.0 1.4 1 1 1 2 2 2 1 ADP-ribosylglycohydrolase zf-MYND PF01753.18 PRP83308.1 - 9.3e-09 35.2 9.8 1.5e-08 34.5 9.8 1.4 1 0 0 1 1 1 1 MYND finger CH PF00307.31 PRP83309.1 - 1.7e-15 57.2 0.2 1.7e-11 44.2 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF4735 PF15882.5 PRP83309.1 - 1.1 8.7 12.0 0.46 9.9 5.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4735) DUF3135 PF11333.8 PRP83309.1 - 6.2 7.1 8.0 11 6.4 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) DUF2947 PF11163.8 PRP83309.1 - 8.4 6.2 8.1 1.4 8.7 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2947) Actin PF00022.19 PRP83310.1 - 2.9e-10 39.3 0.0 3.2e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Actin Actin_micro PF17003.5 PRP83310.1 - 0.00068 18.9 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative actin-like family TPR_2 PF07719.17 PRP83311.1 - 2.8e-09 36.4 10.3 0.032 14.3 0.6 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP83311.1 - 1.9e-08 34.5 9.2 0.14 12.4 0.5 5.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP83311.1 - 1.4e-07 31.2 4.8 0.062 13.5 0.3 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP83311.1 - 3.9e-07 29.6 1.7 0.036 14.1 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP83311.1 - 1e-06 28.3 11.7 0.12 12.3 0.6 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP83311.1 - 3.2e-05 24.1 9.5 0.78 10.0 0.1 5.5 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP83311.1 - 8.4e-05 23.0 4.4 0.77 10.3 0.3 4.8 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP83311.1 - 0.00021 21.8 2.7 5.5 8.1 0.1 5.5 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP83311.1 - 0.0015 18.2 3.9 0.85 9.4 0.7 4.5 5 0 0 5 5 5 1 TPR repeat TPR_16 PF13432.6 PRP83311.1 - 0.0055 17.3 0.1 0.51 11.0 0.2 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF5104 PF17117.5 PRP83311.1 - 0.02 15.3 0.1 0.071 13.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5104) RPN7 PF10602.9 PRP83311.1 - 0.021 14.5 0.0 0.08 12.7 0.0 1.9 1 1 0 1 1 1 0 26S proteasome subunit RPN7 PPR PF01535.20 PRP83311.1 - 0.12 12.7 5.2 54 4.3 0.2 5.5 6 0 0 6 6 5 0 PPR repeat TPR_MalT PF17874.1 PRP83311.1 - 0.19 11.0 1.7 9.4 5.5 0.1 3.4 3 1 1 4 4 4 0 MalT-like TPR region TPR_21 PF09976.9 PRP83311.1 - 0.28 10.9 1.8 5 6.8 1.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain ERK-JNK_inhib PF15002.6 PRP83313.1 - 0.039 13.6 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor FH2 PF02181.23 PRP83316.1 - 1.8e-73 247.9 0.3 1.8e-73 247.9 0.3 2.6 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PRP83316.1 - 8.3e-27 94.1 4.6 2.6e-26 92.4 4.6 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP83316.1 - 5e-24 84.9 2.1 5e-24 84.9 2.1 3.8 5 0 0 5 5 5 1 Diaphanous GTPase-binding Domain C2 PF00168.30 PRP83316.1 - 2.2e-11 43.9 0.0 6.6e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF3361 PF11841.8 PRP83316.1 - 0.0047 16.9 1.4 0.096 12.6 2.8 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) Med30 PF11315.8 PRP83316.1 - 3.9 7.7 8.6 0.48 10.6 0.1 3.7 4 0 0 4 4 4 0 Mediator complex subunit 30 Spindle_Spc25 PF08234.12 PRP83317.1 - 6.7e-12 45.4 0.0 1.6e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF3080 PF11279.8 PRP83317.1 - 0.047 12.9 4.6 0.073 12.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Spc7 PF08317.11 PRP83317.1 - 0.085 11.7 11.1 0.12 11.3 11.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 PRP83317.1 - 1.1 8.3 8.7 1.5 7.9 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATP-synt_Eps PF04627.13 PRP83318.1 - 8.3e-17 60.9 0.8 1.1e-16 60.5 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain CHDCT2 PF08074.11 PRP83318.1 - 0.07 13.3 0.0 0.083 13.1 0.0 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF3591 PF12157.8 PRP83319.1 - 2e-139 465.1 0.0 2e-139 465.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3591) LSM PF01423.22 PRP83319.1 - 5.5e-17 61.2 0.5 1.4e-16 59.9 0.5 1.7 1 0 0 1 1 1 1 LSM domain Bromodomain PF00439.25 PRP83319.1 - 8.2e-16 57.9 0.5 5e-15 55.3 0.5 2.5 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.6 PRP83319.1 - 0.004 16.9 1.2 0.01 15.6 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle Hfq PF17209.3 PRP83319.1 - 0.11 12.2 0.1 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 Hfq protein Rsc14 PF08586.10 PRP83319.1 - 3.9 8.3 7.8 0.93 10.3 0.5 2.9 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Ras PF00071.22 PRP83320.1 - 7.2e-40 136.2 0.1 8.1e-40 136.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP83320.1 - 1.6e-16 60.6 0.1 2.2e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP83320.1 - 8.5e-10 38.4 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP83320.1 - 0.0038 17.3 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 PRP83320.1 - 0.015 15.0 0.1 0.02 14.6 0.1 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 PRP83320.1 - 0.019 15.3 0.0 0.022 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PRP83320.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PRP83320.1 - 0.031 14.2 0.0 2 8.3 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase Septin PF00735.18 PRP83320.1 - 0.034 13.4 0.0 0.065 12.5 0.0 1.4 1 1 0 1 1 1 0 Septin TniB PF05621.11 PRP83320.1 - 0.069 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DUF3425 PF11905.8 PRP83320.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) DUF382 PF04037.13 PRP83321.1 - 4.3e-53 178.8 0.0 4.3e-53 178.8 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF382) PSP PF04046.16 PRP83321.1 - 1.2e-22 79.5 4.5 2.2e-22 78.6 4.5 1.5 1 0 0 1 1 1 1 PSP THOC2_N PF16134.5 PRP83321.1 - 0.0034 16.1 8.3 0.0034 16.1 8.3 2.6 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus Rhodanese PF00581.20 PRP83322.1 - 3.6e-05 24.2 0.0 0.00038 20.9 0.0 2.5 1 1 0 1 1 1 1 Rhodanese-like domain Zeta_toxin PF06414.12 PRP83322.1 - 0.027 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin bact-PGI_C PF10432.9 PRP83322.1 - 0.18 11.8 0.0 0.59 10.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain Rhodanese PF00581.20 PRP83323.1 - 1.6e-14 54.3 0.0 1.9e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DRMBL PF07522.14 PRP83324.1 - 9.7e-10 38.6 0.0 1.9e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 PRP83324.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain COMM_domain PF07258.14 PRP83325.1 - 2.1e-13 50.2 1.1 3.9e-13 49.3 0.4 1.9 2 0 0 2 2 2 1 COMM domain HEAT_2 PF13646.6 PRP83326.1 - 2e-06 28.1 0.1 0.29 11.5 0.0 4.8 4 0 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 PRP83326.1 - 0.00015 22.3 1.8 7.9 7.1 0.0 4.2 3 1 0 3 3 3 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PRP83326.1 - 0.00016 21.8 2.9 0.21 11.6 0.0 4.2 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP83326.1 - 0.00043 20.3 16.2 0.37 11.2 0.0 7.1 9 0 0 9 9 9 3 HEAT repeat Adaptin_N PF01602.20 PRP83326.1 - 0.0083 14.7 0.2 0.03 12.9 0.1 1.9 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_EZ PF13513.6 PRP83326.1 - 0.061 13.8 4.9 11 6.6 0.0 5.1 5 1 0 5 5 5 0 HEAT-like repeat Borrelia_P83 PF05262.11 PRP83326.1 - 0.91 7.9 4.3 1.4 7.4 4.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase_fungal PF17667.1 PRP83327.1 - 9.3e-14 51.0 0.0 5.8e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 PRP83327.1 - 0.00019 21.4 0.1 0.00042 20.3 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP83327.1 - 0.0011 18.6 0.1 0.0021 17.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 PRP83327.1 - 0.0035 16.7 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1752 PF08550.10 PRP83327.1 - 0.34 10.8 1.1 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) Cnd1 PF12717.7 PRP83328.1 - 1.7e-28 99.7 18.1 1e-25 90.7 1.4 6.2 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP83328.1 - 4.9e-06 26.3 14.8 1.3 9.5 0.1 8.1 9 0 0 9 9 9 2 HEAT repeat Cnd3 PF12719.7 PRP83328.1 - 0.0034 16.6 0.1 0.0034 16.6 0.1 3.5 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain TIP120 PF08623.10 PRP83328.1 - 0.017 14.9 0.7 0.19 11.5 0.0 3.1 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 PRP83328.1 - 0.031 12.8 20.1 0.42 9.1 10.7 4.7 2 2 2 4 4 4 0 Adaptin N terminal region RIX1 PF08167.12 PRP83328.1 - 0.11 12.2 0.9 5.6 6.7 0.0 4.2 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis TFCD_C PF12612.8 PRP83328.1 - 0.32 10.8 3.8 1.6 8.5 0.2 4.0 5 1 1 6 6 6 0 Tubulin folding cofactor D C terminal Cyclin_C_2 PF16899.5 PRP83328.1 - 0.51 10.8 2.2 1.9 8.9 0.3 3.0 2 1 0 2 2 2 0 Cyclin C-terminal domain Pkinase_fungal PF17667.1 PRP83329.1 - 8.6e-12 44.5 0.1 3e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 PRP83329.1 - 2.9e-05 24.1 0.2 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP83329.1 - 6.3e-05 22.6 0.0 0.00017 21.3 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 PRP83329.1 - 0.00038 19.9 0.0 0.00059 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP83329.1 - 0.093 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HD_4 PF13328.6 PRP83330.1 - 4.3e-22 78.5 0.1 5.7e-22 78.1 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.22 PRP83330.1 - 3.6e-08 33.7 1.2 8.8e-08 32.4 1.3 1.6 2 0 0 2 2 2 1 HD domain KNOX2 PF03791.13 PRP83330.1 - 0.045 13.3 0.4 0.097 12.2 0.1 1.7 2 0 0 2 2 2 0 KNOX2 domain XH PF03469.14 PRP83330.1 - 0.05 13.5 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 XH domain HD_2 PF12917.7 PRP83330.1 - 0.15 11.8 0.9 0.29 10.8 0.9 1.4 1 1 0 1 1 1 0 HD containing hydrolase-like enzyme bVLRF1 PF18826.1 PRP83331.1 - 3e-38 131.0 3.3 3e-38 131.0 3.3 3.0 2 1 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_3 PF13606.6 PRP83331.1 - 4.3e-07 29.7 0.0 0.0047 17.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 PRP83331.1 - 5.3e-07 30.1 0.0 1.1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP83331.1 - 7.3e-07 29.6 0.0 3.9e-06 27.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP83331.1 - 1.4e-06 28.5 0.0 0.081 13.3 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP83331.1 - 0.00072 19.9 0.1 0.049 14.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Borrelia_P83 PF05262.11 PRP83331.1 - 5.3 5.4 25.7 11 4.4 25.7 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein ZU5 PF00791.20 PRP83332.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 ZU5 domain Gelsolin PF00626.22 PRP83334.1 - 8e-43 144.2 0.1 9.2e-10 38.3 0.0 6.6 5 0 0 5 5 5 5 Gelsolin repeat VHP PF02209.19 PRP83334.1 - 9.1e-14 51.2 0.5 2.8e-13 49.7 0.5 2.0 1 0 0 1 1 1 1 Villin headpiece domain CENP-F_leu_zip PF10473.9 PRP83334.1 - 0.00086 19.3 24.4 0.00086 19.3 24.4 10.0 3 2 6 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 PRP83334.1 - 0.0029 17.3 18.6 0.0029 17.3 18.6 7.9 1 1 5 8 8 8 4 Intermediate filament protein BRE1 PF08647.11 PRP83334.1 - 0.003 17.6 16.3 0.003 17.6 16.3 12.4 4 3 8 12 12 12 1 BRE1 E3 ubiquitin ligase Cnn_1N PF07989.11 PRP83334.1 - 0.082 13.1 0.0 0.082 13.1 0.0 14.8 6 5 6 12 12 12 0 Centrosomin N-terminal motif 1 Prenyltrans PF00432.21 PRP83335.1 - 4.7e-28 96.6 2.1 2.1e-08 33.7 0.0 6.4 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat HEAT PF02985.22 PRP83338.1 - 2.8e-12 45.8 6.3 0.011 16.0 0.0 7.5 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 PRP83338.1 - 9.2e-06 26.0 0.0 5.1 7.5 0.0 5.4 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 PRP83338.1 - 0.0008 19.9 8.5 29 5.3 0.0 7.5 8 0 0 8 8 8 2 HEAT-like repeat RIH_assoc PF08454.11 PRP83338.1 - 7.8 6.4 10.7 32 4.5 0.1 5.1 4 1 0 4 4 4 0 RyR and IP3R Homology associated CLU PF13236.6 PRP83340.1 - 3.5e-55 187.2 0.0 5.8e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP83340.1 - 2.3e-07 31.0 1.0 8.1e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TROVE PF05731.11 PRP83340.1 - 0.0014 17.8 0.3 0.0026 16.9 0.3 1.3 1 0 0 1 1 1 1 TROVE domain TPR_17 PF13431.6 PRP83340.1 - 0.0017 18.6 0.1 0.31 11.5 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83340.1 - 0.0037 17.7 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP83340.1 - 0.058 13.5 0.1 1.2 9.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP83340.1 - 0.16 11.8 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 PRP83341.1 - 3.9e-45 154.1 1.3 3.9e-45 154.1 1.3 2.0 2 1 0 2 2 2 1 Rab-GTPase-TBC domain EF-hand_4 PF12763.7 PRP83341.1 - 1.8e-10 40.7 2.3 3.3e-10 39.8 0.1 2.6 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand SBE2 PF17076.5 PRP83341.1 - 0.00019 19.9 1.4 0.00027 19.3 1.4 1.2 1 0 0 1 1 1 1 SBE2, cell-wall formation PTAC PF06130.12 PRP83341.1 - 0.044 14.0 0.3 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 Phosphate propanoyltransferase Phosphodiest PF01663.22 PRP83342.1 - 2e-88 297.4 0.3 2.4e-88 297.1 0.3 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PRP83342.1 - 5.7e-11 42.4 0.5 1.9e-10 40.6 0.5 1.8 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 PRP83342.1 - 0.0043 16.4 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Polysacc_synt PF01943.17 PRP83342.1 - 0.032 13.6 0.3 0.055 12.8 0.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF229 PF02995.17 PRP83342.1 - 0.086 11.4 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 PRP83342.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) PglZ PF08665.12 PRP83342.1 - 0.15 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 PglZ domain Ribosomal_L37ae PF01780.19 PRP83343.1 - 0.019 15.0 1.4 0.037 14.1 0.8 1.8 1 1 0 1 1 1 0 Ribosomal L37ae protein family GAT PF03127.14 PRP83343.1 - 0.028 14.7 0.1 0.057 13.7 0.1 1.5 1 0 0 1 1 1 0 GAT domain DUF3280 PF11684.8 PRP83343.1 - 0.061 13.7 4.0 0.54 10.7 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2380) Dicty_REP PF05086.12 PRP83343.1 - 1 7.3 4.1 1.4 6.8 4.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIID-18kDa PF02269.16 PRP83344.1 - 4.9e-25 87.4 2.3 7.9e-25 86.7 2.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Zn_Tnp_IS91 PF14319.6 PRP83345.1 - 4.6 7.4 9.1 0.29 11.2 3.3 2.0 3 0 0 3 3 3 0 Transposase zinc-binding domain dNK PF01712.19 PRP83346.1 - 5.8e-40 137.3 0.0 1.7e-39 135.8 0.0 1.7 2 0 0 2 2 2 1 Deoxynucleoside kinase NAD_binding_10 PF13460.6 PRP83346.1 - 2.2e-13 50.5 0.1 4.7e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 PRP83346.1 - 8.5e-12 45.1 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PRP83346.1 - 7.2e-10 38.7 0.3 5e-09 36.0 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PRP83346.1 - 2e-09 36.9 0.0 3.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PRP83346.1 - 2.6e-09 36.6 0.0 5.8e-08 32.2 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain AAA_33 PF13671.6 PRP83346.1 - 1.5e-05 25.2 0.0 3.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PRP83346.1 - 2.2e-05 24.2 0.1 8e-05 22.4 0.1 2.0 1 1 0 1 1 1 1 Thymidylate kinase GDP_Man_Dehyd PF16363.5 PRP83346.1 - 0.00066 19.2 0.3 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase AAA_18 PF13238.6 PRP83346.1 - 0.0026 18.3 0.0 0.01 16.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain adh_short PF00106.25 PRP83346.1 - 0.0033 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 PRP83346.1 - 0.047 12.9 0.2 16 4.5 0.0 3.0 2 1 1 3 3 3 0 Male sterility protein Pertussis_S1 PF02917.14 PRP83349.1 - 0.097 12.4 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 WD40 PF00400.32 PRP83354.1 - 3.4e-20 72.0 4.1 4e-07 30.6 0.1 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP83354.1 - 5.7e-18 65.0 0.0 0.018 15.3 0.0 4.6 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 PRP83354.1 - 6.5e-05 21.4 0.0 0.011 14.1 0.0 2.3 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 PRP83354.1 - 0.00057 18.7 0.2 0.59 8.8 0.0 2.5 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.6 PRP83354.1 - 0.0041 16.7 0.1 2.6 7.6 0.0 2.6 3 0 0 3 3 3 2 PQQ-like domain Ge1_WD40 PF16529.5 PRP83354.1 - 0.0087 15.1 0.0 0.51 9.2 0.0 3.1 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP83354.1 - 0.026 13.2 1.8 1.1 7.8 0.2 2.4 2 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 PRP83354.1 - 0.051 12.9 0.3 2.7 7.2 0.1 2.8 2 1 1 3 3 3 0 WD40-like domain DUF21 PF01595.20 PRP83355.1 - 2e-30 105.8 3.0 4.1e-30 104.8 3.0 1.5 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PRP83355.1 - 0.0001 22.6 2.6 0.068 13.6 0.0 3.8 5 0 0 5 5 5 2 CBS domain ALG3 PF05208.13 PRP83356.1 - 1.9e-142 474.9 18.5 2.7e-142 474.4 18.5 1.2 1 0 0 1 1 1 1 ALG3 protein Zn_clus PF00172.18 PRP83357.1 - 0.0085 16.2 0.9 0.016 15.3 0.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3682 PF12446.8 PRP83357.1 - 0.016 15.7 0.1 0.027 14.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Ribonuc_red_2_N PF08471.10 PRP83357.1 - 0.033 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase HAUS4 PF14735.6 PRP83357.1 - 0.072 12.8 0.1 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 Tocopherol_cycl PF14249.6 PRP83358.1 - 4.6e-10 39.2 0.8 5.6e-09 35.6 0.8 2.0 1 1 0 1 1 1 1 Tocopherol cyclase DDT PF02791.17 PRP83360.1 - 0.024 14.9 0.0 0.044 14.1 0.0 1.4 1 0 0 1 1 1 0 DDT domain YqbF PF14553.6 PRP83360.1 - 0.031 14.1 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Proteasome PF00227.26 PRP83361.1 - 1.1e-56 191.4 0.0 2.1e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PRP83361.1 - 3.6e-13 48.9 0.0 1.2e-12 47.3 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature LRR_9 PF14580.6 PRP83362.1 - 4.1e-13 49.2 0.9 4.1e-13 49.2 0.9 1.8 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 PRP83362.1 - 4.2e-12 46.1 11.9 4.3e-06 27.0 3.4 2.9 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP83362.1 - 8.4e-08 31.9 10.2 2.6e-06 27.1 1.5 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 PRP83362.1 - 1.8 9.4 6.3 82 4.4 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 PRP83362.1 - 1.9 8.7 0.0 1.9 8.7 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeat Peptidase_S64 PF08192.11 PRP83362.1 - 7.6 4.9 6.8 12 4.2 6.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF1619 PF07773.11 PRP83363.1 - 1.9e-19 70.7 32.1 3.3e-12 47.0 20.1 4.0 3 1 0 3 3 3 3 Protein of unknown function (DUF1619) Ribosomal_L30 PF00327.20 PRP83363.1 - 1.9e-19 69.2 1.8 6.6e-19 67.6 1.8 2.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 PRP83363.1 - 2.1e-18 66.3 12.2 3.3e-18 65.7 12.2 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain SOG2 PF10428.9 PRP83363.1 - 0.011 15.0 26.4 0.0066 15.7 17.5 2.3 2 0 0 2 2 2 0 RAM signalling pathway protein ATG16 PF08614.11 PRP83364.1 - 4.1e-05 23.9 26.7 7e-05 23.2 26.7 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Filament PF00038.21 PRP83364.1 - 0.023 14.3 26.0 0.15 11.6 4.8 3.0 1 1 2 3 3 3 0 Intermediate filament protein CEP63 PF17045.5 PRP83364.1 - 0.096 12.6 30.9 0.04 13.8 12.5 2.5 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Laminin_II PF06009.12 PRP83364.1 - 0.79 9.7 18.0 0.55 10.3 1.0 3.3 2 1 2 4 4 4 0 Laminin Domain II DUF5127 PF17168.4 PRP83364.1 - 0.86 9.3 4.6 0.79 9.4 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5127) Spc7 PF08317.11 PRP83364.1 - 1.1 8.1 30.8 1.4 7.7 13.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ERM PF00769.19 PRP83364.1 - 1.1 9.0 30.9 2.1 8.1 30.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CALCOCO1 PF07888.11 PRP83364.1 - 1.1 8.0 30.1 1.7 7.4 30.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DASH_Dam1 PF08653.10 PRP83364.1 - 1.1 9.0 7.8 4.6 7.1 0.6 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 ADIP PF11559.8 PRP83364.1 - 1.3 9.1 27.4 0.67 10.0 12.3 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.21 PRP83364.1 - 1.4 9.4 26.1 0.07 13.6 4.6 2.8 2 1 1 3 3 3 0 Spectrin repeat SpecificRecomb PF10136.9 PRP83364.1 - 3.4 5.8 6.8 1.7 6.8 3.8 1.3 1 1 0 1 1 1 0 Site-specific recombinase SHE3 PF17078.5 PRP83364.1 - 4 7.1 27.1 42 3.7 26.9 2.4 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 FliD_N PF02465.18 PRP83364.1 - 4.2 8.1 13.9 0.11 13.2 3.0 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Baculo_PEP_C PF04513.12 PRP83364.1 - 4.4 7.4 7.4 2.9 7.9 1.9 2.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMMR_N PF15905.5 PRP83364.1 - 5.8 6.3 32.4 9.2 5.6 28.6 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4200 PF13863.6 PRP83364.1 - 6.4 7.2 32.2 5.2 7.5 18.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.14 PRP83364.1 - 8.1 6.8 29.6 5.2 7.4 9.9 3.2 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) FAM184 PF15665.5 PRP83364.1 - 8.5 6.1 31.6 0.75 9.5 10.3 2.7 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B DUF948 PF06103.11 PRP83364.1 - 8.8 6.7 12.3 3.7 7.9 1.0 3.7 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 PRP83364.1 - 8.9 7.0 26.2 0.37 11.4 5.6 3.6 2 1 1 3 3 3 0 Initiation control protein YabA KxDL PF10241.9 PRP83364.1 - 9 6.6 23.3 0.63 10.4 1.5 4.0 2 1 2 4 4 4 0 Uncharacterized conserved protein APG12 PF04110.13 PRP83365.1 - 1.8e-27 95.6 0.1 2.3e-27 95.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 PRP83365.1 - 1.7e-09 37.8 0.0 2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like LIM PF00412.22 PRP83366.1 - 4e-19 68.6 23.4 2.7e-10 40.3 6.1 3.1 3 0 0 3 3 3 2 LIM domain TF_Zn_Ribbon PF08271.12 PRP83366.1 - 0.087 12.4 0.1 0.087 12.4 0.1 3.8 5 0 0 5 5 5 0 TFIIB zinc-binding eIF-5_eIF-2B PF01873.17 PRP83366.1 - 0.43 10.5 9.8 0.11 12.4 0.7 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 FdhE PF04216.12 PRP83366.1 - 9.5 6.0 12.2 9.4 6.0 6.2 2.2 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation PAP_central PF04928.17 PRP83367.1 - 1.1e-24 86.8 0.0 2.1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 PRP83367.1 - 2.7e-05 23.9 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Exo_endo_phos PF03372.23 PRP83367.1 - 0.0015 18.1 0.0 0.0027 17.2 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4269 PF14091.6 PRP83367.1 - 0.058 13.6 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) Complex1_LYR PF05347.15 PRP83368.1 - 5.4e-13 48.8 0.4 7.8e-13 48.3 0.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 PRP83368.1 - 0.0083 16.7 0.4 0.012 16.2 0.4 1.4 1 1 0 1 1 1 1 Complex1_LYR-like S4 PF01479.25 PRP83369.1 - 4.1e-11 42.4 0.1 9.8e-11 41.2 0.1 1.6 1 0 0 1 1 1 1 S4 domain Laminin_G_3 PF13385.6 PRP83371.1 - 2.9e-37 128.2 4.5 3.1e-19 69.6 0.3 2.7 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Toxin_R_bind_N PF07953.12 PRP83371.1 - 0.00013 21.8 2.4 0.21 11.3 0.0 3.0 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding Laminin_G_2 PF02210.24 PRP83371.1 - 0.12 12.9 0.0 1.6 9.3 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain Septin PF00735.18 PRP83372.1 - 5.6e-18 65.2 1.2 8.1e-14 51.6 0.1 2.6 1 1 0 2 2 2 2 Septin CcmE PF03100.15 PRP83372.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 CcmE RRM_1 PF00076.22 PRP83374.1 - 7.9e-76 249.9 6.4 2.7e-17 62.3 0.3 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP83374.1 - 2.8e-11 43.1 0.5 0.01 15.4 0.0 5.2 4 1 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PRP83374.1 - 1.3e-05 24.9 0.6 3.4 7.6 0.0 4.8 5 0 0 5 5 5 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PRP83374.1 - 0.00033 20.6 0.1 13 5.9 0.0 4.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 PRP83374.1 - 0.0045 17.0 0.1 0.94 9.5 0.0 3.2 3 0 0 3 3 3 1 RNA binding domain DUF3431 PF11913.8 PRP83374.1 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4981 PF16353.5 PRP83374.1 - 0.13 12.8 1.1 3.7 8.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function(DUF4981) RRM_7 PF16367.5 PRP83374.1 - 0.44 10.7 3.2 7.9 6.7 0.0 4.3 6 0 0 6 6 6 0 RNA recognition motif Perilipin PF03036.16 PRP83375.1 - 4e-11 42.6 12.6 9.6e-08 31.5 1.0 2.2 1 1 1 2 2 2 2 Perilipin family DUF3080 PF11279.8 PRP83375.1 - 0.0029 16.9 2.5 0.025 13.8 1.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3080) HisKA PF00512.25 PRP83375.1 - 0.006 16.6 0.8 0.03 14.4 0.8 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Fzo_mitofusin PF04799.13 PRP83375.1 - 0.075 12.6 3.2 0.062 12.8 0.9 1.9 2 0 0 2 2 2 0 fzo-like conserved region COG5 PF10392.9 PRP83375.1 - 0.28 11.4 10.5 0.19 11.9 6.8 2.6 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Phage_fiber_2 PF03406.13 PRP83375.1 - 0.73 9.4 4.4 0.76 9.4 0.6 2.6 2 0 0 2 2 2 0 Phage tail fibre repeat DUF948 PF06103.11 PRP83375.1 - 1.4 9.2 6.3 18 5.7 0.4 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) AATF-Che1 PF13339.6 PRP83375.1 - 2.4 8.9 6.9 11 6.6 1.4 2.9 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor IPPT PF01715.17 PRP83376.1 - 0.00091 19.1 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 IPP transferase ACPS PF01648.20 PRP83377.1 - 0.017 15.3 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily PP2C PF00481.21 PRP83378.1 - 1.8e-68 231.0 0.6 1.8e-68 231.0 0.6 1.5 1 1 1 2 2 2 1 Protein phosphatase 2C Alb1 PF09135.11 PRP83378.1 - 0.8 10.6 5.9 0.2 12.5 0.4 2.7 2 2 1 3 3 3 0 Alb1 WD40 PF00400.32 PRP83379.1 - 1.4e-35 120.7 27.9 9.8e-09 35.7 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP83379.1 - 4.7e-08 33.2 1.7 0.5 10.7 0.1 4.7 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP83379.1 - 0.00013 22.0 0.2 0.15 11.9 0.2 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 PRP83379.1 - 0.056 12.4 0.5 1.9 7.3 0.2 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 PRP83379.1 - 0.087 11.8 1.4 5.2 5.9 0.2 3.5 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3450 PF11932.8 PRP83379.1 - 0.19 11.0 4.8 0.36 10.1 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 PRP83379.1 - 0.27 9.1 5.6 0.5 8.2 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LCD1 PF09798.9 PRP83379.1 - 0.75 8.2 9.1 0.92 7.9 9.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein TcdB_N PF12918.7 PRP83379.1 - 1.6 9.0 6.6 5.2 7.4 5.1 2.5 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain ATP-synt_C PF00137.21 PRP83380.1 - 5.1e-36 122.8 39.4 7.5e-23 80.6 15.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Glycophorin_A PF01102.18 PRP83380.1 - 0.24 11.6 3.0 0.5 10.6 3.0 1.5 1 0 0 1 1 1 0 Glycophorin A Ribosomal_S3Ae PF01015.18 PRP83381.1 - 2e-92 308.3 8.4 2.3e-92 308.1 8.4 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 PRP83381.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region CutC PF03932.14 PRP83382.1 - 7.6e-60 201.9 0.6 1.1e-59 201.3 0.6 1.3 1 0 0 1 1 1 1 CutC family TB2_DP1_HVA22 PF03134.19 PRP83383.1 - 3.7e-16 58.8 4.7 3.7e-16 58.8 4.7 2.3 2 1 1 3 3 3 1 TB2/DP1, HVA22 family BTB_2 PF02214.22 PRP83384.1 - 8.1e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.32 PRP83385.1 - 7.3e-08 33.0 5.8 0.7 10.9 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat PHD PF00628.29 PRP83385.1 - 1.3e-05 25.0 14.1 1.4e-05 24.9 11.6 2.2 2 0 0 2 2 2 1 PHD-finger ANAPC4_WD40 PF12894.7 PRP83385.1 - 2.4e-05 24.6 0.0 1.8 8.9 0.0 4.4 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Forkhead PF00250.18 PRP83385.1 - 0.013 15.7 0.0 6.1 7.2 0.0 2.9 2 0 0 2 2 2 0 Forkhead domain PHD_2 PF13831.6 PRP83385.1 - 4.7 6.9 8.9 1.4 8.5 5.7 1.9 2 0 0 2 2 2 0 PHD-finger tRNA-synt_2c PF01411.19 PRP83386.1 - 4e-168 560.4 0.0 4e-168 560.4 0.0 2.4 4 0 0 4 4 4 1 tRNA synthetases class II (A) Slu7 PF11708.8 PRP83386.1 - 3e-77 260.0 22.1 3e-77 260.0 22.1 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor tRNA_SAD PF07973.14 PRP83386.1 - 3.8e-15 55.7 0.2 9.1e-15 54.5 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 PRP83386.1 - 0.02 15.3 2.6 0.03 14.7 0.7 2.3 2 0 0 2 2 2 0 DHHA1 domain zf-CCHC_4 PF14392.6 PRP83386.1 - 0.61 9.9 2.5 1.5 8.6 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle Evr1_Alr PF04777.13 PRP83387.1 - 4.2e-29 101.0 1.5 4.2e-29 101.0 1.5 1.5 2 0 0 2 2 2 1 Erv1 / Alr family WD40 PF00400.32 PRP83388.1 - 6.8e-10 39.4 5.9 0.93 10.5 0.0 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP83388.1 - 6.1e-08 32.9 0.6 6 7.2 0.0 5.5 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP83388.1 - 0.00094 18.6 0.8 0.0058 16.0 0.2 2.1 2 0 0 2 2 2 1 WD40-like domain DPCD PF14913.6 PRP83389.1 - 2.1e-56 190.3 2.0 2.6e-56 190.0 2.0 1.0 1 0 0 1 1 1 1 DPCD protein family Pkinase PF00069.25 PRP83390.1 - 1.4e-64 218.0 0.6 2.5e-64 217.2 0.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Methyltransf_3 PF01596.17 PRP83390.1 - 1.4e-39 135.5 0.0 2.7e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Pkinase_Tyr PF07714.17 PRP83390.1 - 1.7e-37 129.2 0.2 2.9e-37 128.4 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UPF0176_N PF17773.1 PRP83390.1 - 1.7e-19 70.0 0.0 5.6e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese_C PF12368.8 PRP83390.1 - 9.1e-12 45.2 9.5 2e-11 44.1 9.5 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal Rhodanese PF00581.20 PRP83390.1 - 4.6e-09 36.8 0.0 2.2e-08 34.6 0.0 2.2 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_24 PF13578.6 PRP83390.1 - 7.5e-09 36.6 0.0 2.2e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain GATase_4 PF13230.6 PRP83390.1 - 4.8e-07 28.9 0.6 2.7e-06 26.5 0.0 2.4 3 0 0 3 3 3 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 PRP83390.1 - 5e-07 30.0 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Haspin_kinase PF12330.8 PRP83390.1 - 2.7e-06 26.6 1.0 5e-06 25.7 1.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP83390.1 - 0.00018 20.9 0.2 0.00045 19.6 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP83390.1 - 0.00044 19.7 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP83390.1 - 0.00056 18.8 0.0 0.00096 18.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 PRP83390.1 - 0.016 14.8 1.1 0.065 12.8 0.1 2.4 3 0 0 3 3 3 0 RIO1 family Sld5 PF05916.11 PRP83392.1 - 6e-16 58.9 0.6 1e-15 58.1 0.6 1.4 1 1 0 1 1 1 1 GINS complex protein Nuf2 PF03800.14 PRP83394.1 - 1.3e-23 83.7 1.5 4.3e-23 82.0 0.2 2.6 3 0 0 3 3 3 1 Nuf2 family DHR10 PF18595.1 PRP83394.1 - 3.7e-12 46.3 22.9 3.7e-12 46.3 22.9 4.0 3 1 1 4 4 4 2 Designed helical repeat protein 10 domain NeA_P2 PF12312.8 PRP83394.1 - 0.016 14.7 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein RPW8 PF05659.11 PRP83394.1 - 0.33 10.7 7.1 1.1 8.9 0.6 3.5 2 2 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FUSC PF04632.12 PRP83394.1 - 10 4.5 16.1 3.2 6.2 13.0 1.7 1 1 0 1 1 1 0 Fusaric acid resistance protein family VWA_2 PF13519.6 PRP83395.1 - 6.3e-09 36.4 0.0 3.3e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain CarboxypepD_reg PF13620.6 PRP83396.1 - 2.7e-11 43.6 0.8 2.7e-11 43.6 0.8 2.7 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PRP83396.1 - 4.4e-07 29.8 0.6 1.1e-06 28.5 0.2 1.9 2 0 0 2 2 2 1 CarboxypepD_reg-like domain NCU-G1 PF15065.6 PRP83396.1 - 0.01 14.9 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 Ependymin PF00811.18 PRP83396.1 - 0.063 13.5 0.3 0.34 11.1 0.3 2.1 1 1 0 1 1 1 0 Ependymin Lactonase PF10282.9 PRP83397.1 - 1.7e-85 287.3 0.1 2e-85 287.1 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller RhgB_N PF09284.10 PRP83397.1 - 0.078 12.5 0.1 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Rhamnogalacturonan lyase B, N-terminal AAA_16 PF13191.6 PRP83399.1 - 9.4e-35 120.5 0.0 2.8e-34 119.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP83399.1 - 1e-27 97.2 0.9 1.8e-27 96.4 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Response_reg PF00072.24 PRP83399.1 - 8.1e-22 77.5 0.0 2.1e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 PRP83399.1 - 1.5e-21 77.0 0.2 3.7e-21 75.7 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 PRP83399.1 - 8.9e-16 57.9 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HisKA PF00512.25 PRP83399.1 - 9.1e-09 35.2 0.1 3.2e-08 33.5 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 PRP83399.1 - 6.7e-07 30.0 0.1 1.9e-06 28.5 0.1 1.9 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 PRP83399.1 - 8e-06 26.2 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 PRP83399.1 - 0.00031 20.6 0.1 0.0008 19.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinase-like PF14531.6 PRP83399.1 - 0.0021 17.4 0.0 0.0079 15.5 0.0 1.9 1 1 1 2 2 2 1 Kinase-like HATPase_c_5 PF14501.6 PRP83399.1 - 0.0031 17.4 1.3 0.013 15.4 0.0 2.6 2 0 0 2 2 2 1 GHKL domain ATPase_2 PF01637.18 PRP83399.1 - 0.0045 16.9 0.0 0.016 15.2 0.0 2.0 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 PRP83399.1 - 0.0065 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 PRP83399.1 - 0.01 15.1 0.1 0.06 12.5 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 PRP83399.1 - 0.012 15.8 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Guanylate_cyc PF00211.20 PRP83400.1 - 5.9e-54 182.5 0.0 7.6e-29 100.6 0.0 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain FliG_M PF14841.6 PRP83400.1 - 0.049 13.9 0.2 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 FliG middle domain S-AdoMet_synt_C PF02773.16 PRP83400.1 - 0.18 11.8 0.1 0.45 10.5 0.1 1.6 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain Kelch_3 PF13415.6 PRP83401.1 - 2.2e-21 75.6 5.6 0.00021 21.5 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 PRP83401.1 - 1.6e-19 69.6 10.2 5.5e-08 32.7 0.0 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP83401.1 - 2.1e-10 40.5 2.3 0.047 14.0 0.0 5.2 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 PRP83401.1 - 1.7e-09 37.5 1.2 0.082 12.9 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 PRP83401.1 - 1.3e-08 34.3 0.4 0.0042 16.6 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 PRP83401.1 - 4.1e-05 23.4 2.0 0.91 9.6 0.0 4.7 5 0 0 5 5 5 2 Kelch motif DUF3324 PF11797.8 PRP83402.1 - 0.045 13.7 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) Mon1 PF03164.14 PRP83404.1 - 5.3e-136 453.9 0.0 6.2e-136 453.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 HEAT_2 PF13646.6 PRP83406.1 - 5.2e-09 36.4 2.4 0.13 12.7 0.0 7.2 7 1 2 9 9 9 3 HEAT repeats HEAT PF02985.22 PRP83406.1 - 1.7e-07 30.9 6.8 0.61 10.5 0.0 7.6 7 0 0 7 7 6 3 HEAT repeat CLASP_N PF12348.8 PRP83406.1 - 7.8e-06 25.6 0.0 0.0009 18.9 0.0 4.2 4 0 0 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 PRP83406.1 - 1.2e-05 25.5 0.0 2.4 8.4 0.0 5.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 PRP83406.1 - 3.4e-05 23.1 0.1 0.017 14.2 0.0 4.4 5 1 1 6 6 6 1 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 PRP83406.1 - 3.7e-05 24.2 0.0 2.5 8.8 0.0 6.0 7 0 0 7 7 6 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 PRP83406.1 - 0.00056 20.1 0.1 0.43 10.7 0.0 3.0 3 0 0 3 3 3 2 Parkin co-regulated protein HEAT_EZ PF13513.6 PRP83406.1 - 0.001 19.5 10.5 3.3 8.3 0.0 7.7 9 1 1 10 10 10 2 HEAT-like repeat Cnd1 PF12717.7 PRP83406.1 - 0.0087 16.1 1.7 96 3.0 0.0 5.6 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 PRP83406.1 - 0.024 14.2 0.4 43 3.6 0.0 5.5 6 1 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 PRP83406.1 - 0.031 14.3 0.0 2.9 8.1 0.0 3.9 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat CRM1_repeat_3 PF18787.1 PRP83406.1 - 0.17 12.0 0.0 55 4.0 0.0 3.5 3 0 0 3 3 3 0 CRM1 / Exportin repeat 3 bZIP_1 PF00170.21 PRP83412.1 - 2.4e-05 24.3 10.7 5.2e-05 23.3 10.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor BRE1 PF08647.11 PRP83412.1 - 0.0053 16.8 9.6 0.0096 16.0 9.6 1.3 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase bZIP_2 PF07716.15 PRP83412.1 - 0.0059 16.7 12.5 0.0082 16.2 10.9 2.1 1 1 1 2 2 2 1 Basic region leucine zipper CENP-F_leu_zip PF10473.9 PRP83412.1 - 0.017 15.1 10.1 0.032 14.3 10.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Methyltransf_10 PF05971.12 PRP83412.1 - 0.045 13.1 0.1 0.069 12.5 0.1 1.3 1 0 0 1 1 1 0 RNA methyltransferase bZIP_Maf PF03131.17 PRP83412.1 - 0.16 12.5 7.7 0.37 11.3 7.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6_N PF17675.1 PRP83412.1 - 0.18 12.4 8.1 0.32 11.5 8.1 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5384 PF17358.2 PRP83412.1 - 0.55 10.3 8.4 0.95 9.5 8.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5384) RITA PF17066.5 PRP83412.1 - 0.7 9.4 8.5 7.3 6.1 0.0 3.1 2 1 1 3 3 3 0 RBPJ-interacting and tubulin associated protein DivIC PF04977.15 PRP83412.1 - 1 9.1 4.3 0.73 9.6 2.3 1.8 1 1 0 1 1 1 0 Septum formation initiator JIP_LZII PF16471.5 PRP83412.1 - 2.1 8.6 10.3 1.4 9.1 2.6 2.4 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II EF-hand_1 PF00036.32 PRP83413.1 - 1.6e-13 49.1 0.0 0.00013 21.2 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PRP83413.1 - 1.2e-12 46.7 0.0 0.00014 21.5 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 PRP83413.1 - 3.1e-12 46.8 0.0 1.8e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP83413.1 - 2.3e-09 37.0 0.0 0.00046 20.0 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PRP83413.1 - 8.3e-08 31.4 0.0 0.0021 17.5 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 PRP83413.1 - 0.004 17.4 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Grg1 PF11034.8 PRP83414.1 - 4.4e-31 106.9 11.1 5.8e-31 106.5 11.1 1.2 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DoxX PF07681.12 PRP83415.1 - 0.36 11.5 5.3 0.54 10.9 0.6 2.6 2 1 1 3 3 3 0 DoxX YdjM PF04307.14 PRP83415.1 - 0.56 9.5 11.5 0.53 9.6 10.1 1.8 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Pkinase_Tyr PF07714.17 PRP83416.1 - 2.9e-06 26.7 0.2 0.00014 21.3 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP83416.1 - 0.0015 17.9 0.0 0.19 11.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain LRR_4 PF12799.7 PRP83417.1 - 0.021 15.2 0.1 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP83417.1 - 0.025 14.3 0.2 5.1 6.9 0.0 2.6 2 1 0 2 2 2 0 Leucine rich repeat DUF4381 PF14316.6 PRP83418.1 - 0.099 12.9 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 PRP83418.1 - 0.15 11.9 1.7 0.19 11.6 0.6 1.7 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain zf-AN1 PF01428.16 PRP83418.1 - 0.17 12.1 0.1 0.17 12.1 0.1 2.0 3 0 0 3 3 3 0 AN1-like Zinc finger EphA2_TM PF14575.6 PRP83418.1 - 0.18 12.7 0.2 0.23 12.4 0.2 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PsbX PF06596.11 PRP83418.1 - 9.4 6.3 11.8 1.1 9.3 5.5 2.3 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) Atg8 PF02991.16 PRP83419.1 - 2.8e-45 152.7 0.1 4.3e-45 152.2 0.1 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 PRP83419.1 - 7.2e-07 29.5 0.1 1.5e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 G-patch_2 PF12656.7 PRP83420.1 - 6.4e-16 58.2 0.0 6.4e-16 58.2 0.0 2.5 3 0 0 3 3 3 1 G-patch domain KN17_SH3 PF18131.1 PRP83420.1 - 9e-10 38.5 0.0 4.7e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain G-patch PF01585.23 PRP83420.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 G-patch domain Acylphosphatase PF00708.18 PRP83420.1 - 0.025 15.0 0.4 2.6 8.5 0.2 2.6 2 0 0 2 2 2 0 Acylphosphatase KOW PF00467.29 PRP83420.1 - 0.032 14.2 0.1 0.032 14.2 0.1 3.0 3 0 0 3 3 3 0 KOW motif FXMRP1_C_core PF12235.8 PRP83420.1 - 2.8 8.6 8.1 6.6 7.4 7.5 1.9 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal Conotoxin PF02950.17 PRP83420.1 - 2.8 9.0 4.8 41 5.3 0.1 2.3 2 0 0 2 2 2 0 Conotoxin FlgI PF02119.16 PRP83421.1 - 0.058 12.3 0.2 4.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Flagellar P-ring protein EPO_TPO PF00758.18 PRP83421.1 - 0.077 13.0 0.4 0.18 11.9 0.1 1.8 2 1 0 2 2 2 0 Erythropoietin/thrombopoietin HTH_29 PF13551.6 PRP83423.1 - 0.0034 17.4 0.0 0.0082 16.1 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 PRP83423.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_22 PF13309.6 PRP83423.1 - 0.27 11.4 0.6 1 9.5 0.0 2.2 2 0 0 2 2 2 0 HTH domain DUF3592 PF12158.8 PRP83424.1 - 2.3e-13 50.4 0.0 4.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Neuraminidase PF18413.1 PRP83424.1 - 0.043 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Neuraminidase-like domain UCH PF00443.29 PRP83426.1 - 1e-52 179.2 0.4 2.5e-52 177.9 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP83426.1 - 8.9e-30 104.4 0.4 3.3e-29 102.5 0.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 PRP83426.1 - 1.9e-08 33.9 0.4 2e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 Ubiquitin_2 PF14560.6 PRP83426.1 - 0.0012 19.2 6.0 6.9 7.2 0.0 4.8 5 0 0 5 5 5 2 Ubiquitin-like domain ubiquitin PF00240.23 PRP83426.1 - 0.018 14.8 0.5 1.6 8.6 0.0 3.5 4 0 0 4 4 4 0 Ubiquitin family USP7_C2 PF14533.6 PRP83426.1 - 0.072 12.8 0.1 0.072 12.8 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-specific protease C-terminal LRR_6 PF13516.6 PRP83427.1 - 7.3e-12 44.3 9.9 0.015 15.3 0.0 5.5 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 PRP83427.1 - 0.0001 22.6 3.1 0.45 11.0 0.0 4.0 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP83427.1 - 0.0083 16.5 5.4 6.5 7.7 0.0 5.6 7 2 0 7 7 7 1 Leucine Rich Repeat Ras PF00071.22 PRP83428.1 - 3.8e-60 202.2 1.8 4.6e-60 201.9 1.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP83428.1 - 9.5e-32 109.7 2.1 1.8e-31 108.9 0.2 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP83428.1 - 3e-16 59.4 0.6 3.7e-16 59.1 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP83428.1 - 1.4e-07 31.5 2.8 0.0075 16.2 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP83428.1 - 1.4e-06 28.0 0.8 4.5e-06 26.3 0.8 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP83428.1 - 6.6e-06 26.2 0.2 1.3e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 PRP83428.1 - 0.00011 21.6 0.6 0.00059 19.2 0.0 1.9 2 0 0 2 2 2 1 Septin Gtr1_RagA PF04670.12 PRP83428.1 - 0.00016 21.1 0.6 0.00024 20.6 0.6 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 PRP83428.1 - 0.0003 20.1 5.3 0.046 12.9 2.5 2.9 1 1 1 2 2 2 2 G-protein alpha subunit AAA_16 PF13191.6 PRP83428.1 - 0.0023 18.3 0.0 0.0038 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 PRP83428.1 - 0.0028 17.1 0.7 0.0046 16.4 0.7 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.6 PRP83428.1 - 0.012 15.4 0.0 0.017 14.8 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 PRP83428.1 - 0.014 15.2 0.0 0.051 13.3 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 PRP83428.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PRP83428.1 - 0.033 14.7 1.2 0.068 13.7 1.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 PRP83428.1 - 0.033 14.6 0.4 1.1 9.7 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 PRP83428.1 - 0.052 13.1 0.2 6.3 6.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Hpr_kinase_C PF07475.12 PRP83428.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_5 PF07728.14 PRP83428.1 - 0.11 12.6 0.1 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP83428.1 - 0.12 12.6 0.1 0.38 11.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain Homeodomain PF00046.29 PRP83429.1 - 6e-08 32.4 3.1 9.5e-08 31.8 3.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP83429.1 - 0.016 15.1 0.5 0.029 14.3 0.5 1.5 1 0 0 1 1 1 0 Homeobox KN domain Homez PF11569.8 PRP83429.1 - 0.03 13.8 0.3 0.045 13.2 0.3 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Pinin_SDK_memA PF04696.13 PRP83431.1 - 1e-18 67.6 9.6 1e-18 67.6 9.6 4.2 2 2 2 4 4 4 1 pinin/SDK/memA/ protein conserved region DUF1062 PF06353.12 PRP83431.1 - 7.7 7.3 6.9 0.53 11.1 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) PDZ_6 PF17820.1 PRP83432.1 - 0.21 11.5 0.7 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 PDZ domain Suv3_C_1 PF18147.1 PRP83434.1 - 1.9e-14 53.2 0.0 3.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 PRP83434.1 - 1.1e-11 44.5 0.3 4.5e-11 42.5 0.3 2.2 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 PRP83434.1 - 4.9e-08 33.3 0.0 1.5e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ebp2 PF05890.12 PRP83435.1 - 2e-52 178.4 34.3 2e-52 178.4 34.3 1.7 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 MIP PF00230.20 PRP83436.1 - 1.3e-61 208.2 16.7 2.1e-61 207.5 16.7 1.3 1 0 0 1 1 1 1 Major intrinsic protein Synapsin PF02078.16 PRP83436.1 - 0.12 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Synapsin, N-terminal domain RIX1 PF08167.12 PRP83437.1 - 0.078 12.7 0.7 1.7 8.3 0.1 2.6 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis RBD-FIP PF09457.10 PRP83438.1 - 0.2 11.6 0.7 2.4 8.2 0.2 2.3 2 0 0 2 2 2 0 FIP domain DUF5060 PF16586.5 PRP83439.1 - 3.8e-10 40.0 1.0 1.8e-09 37.8 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF5060) Colipase-like PF15083.6 PRP83439.1 - 0.0023 18.0 12.0 0.0039 17.3 12.0 1.3 1 0 0 1 1 1 1 Colipase-like Y_Y_Y PF07495.13 PRP83439.1 - 0.015 15.2 0.1 1 9.3 0.0 3.3 2 0 0 2 2 2 0 Y_Y_Y domain Glyco_hydro_2_C PF02836.17 PRP83439.1 - 0.083 12.0 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DSRB PF10781.9 PRP83441.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Dextransucrase DSRB Hydrolase_3 PF08282.12 PRP83442.1 - 2.4e-48 165.1 0.0 2.8e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PRP83442.1 - 8.2e-16 58.3 0.1 3.9e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PRP83442.1 - 3.9e-09 37.1 0.0 1.1e-08 35.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PRP83442.1 - 0.0026 17.9 0.1 0.027 14.6 0.0 2.4 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 PRP83442.1 - 0.0039 17.6 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 PRP83442.1 - 0.0072 15.5 0.0 0.89 8.6 0.0 2.1 2 0 0 2 2 2 2 Trehalose-phosphatase Cast PF10174.9 PRP83442.1 - 0.1 10.8 0.0 0.14 10.4 0.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Tic110 PF16940.5 PRP83442.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter GFA PF04828.14 PRP83443.1 - 3.4e-17 62.6 0.8 5.4e-17 61.9 0.8 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 PRP83443.1 - 0.046 13.9 0.2 0.046 13.9 0.2 2.6 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) FHA PF00498.26 PRP83444.1 - 2.9e-16 59.6 0.0 6.1e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PRP83444.1 - 6.8e-11 42.3 0.0 1.6e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain OCRE PF17780.1 PRP83444.1 - 1.4 9.0 13.0 1.2 9.2 1.3 3.1 2 1 0 2 2 2 0 OCRE domain EF-hand_1 PF00036.32 PRP83449.1 - 1.4e-10 39.9 5.3 0.00012 21.4 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PRP83449.1 - 1.7e-09 38.0 0.3 0.00019 21.8 1.2 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP83449.1 - 5.2e-08 32.2 2.4 0.006 16.4 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP83449.1 - 2.6e-06 26.7 4.3 0.0019 17.6 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PRP83449.1 - 0.0026 17.6 6.5 0.024 14.4 0.3 3.2 2 1 1 3 3 3 1 EF-hand domain pair G10 PF01125.17 PRP83449.1 - 0.0099 15.6 5.4 0.021 14.6 5.4 1.5 1 0 0 1 1 1 1 G10 protein Pox_MCEL PF03291.16 PRP83451.1 - 6.7e-73 245.7 0.0 1.2e-72 244.8 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 PRP83451.1 - 2.8e-07 31.1 0.0 5.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP83451.1 - 6.5e-06 26.1 0.0 1.5e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP83451.1 - 0.00012 22.8 0.0 0.00024 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP83451.1 - 0.00044 20.9 0.0 0.00073 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.32 PRP83452.1 - 4e-21 74.9 10.0 0.00073 20.3 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP83452.1 - 5.9e-09 36.1 0.6 0.00092 19.5 0.0 4.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PRP83452.1 - 5.1e-05 23.0 0.9 0.0003 20.5 1.0 1.9 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 PRP83452.1 - 0.00058 18.9 0.1 9 5.1 0.0 3.6 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PRP83452.1 - 0.0059 16.0 0.4 0.15 11.4 0.1 2.1 1 1 1 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 PRP83452.1 - 0.011 16.3 0.1 4.4 7.9 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 PRP83452.1 - 0.12 12.3 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Sigma70_ner PF04546.13 PRP83452.1 - 1.2 9.0 10.1 1.1 9.2 0.3 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region SCIMP PF15050.6 PRP83453.1 - 0.0043 17.5 0.6 0.0062 17.0 0.6 1.2 1 0 0 1 1 1 1 SCIMP protein DUF2062 PF09835.9 PRP83453.1 - 0.057 13.3 0.0 0.066 13.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) ATP-synt_S1 PF05827.12 PRP83453.1 - 0.088 12.6 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) MR_MLE_C PF13378.6 PRP83454.1 - 1.1e-42 146.2 0.2 7.4e-42 143.4 0.2 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 PRP83454.1 - 0.00027 21.1 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 PRP83454.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Y_phosphatase PF00102.27 PRP83455.1 - 6.3e-70 235.4 0.1 7.4e-70 235.2 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PRP83455.1 - 0.00098 18.9 0.1 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PRP83455.1 - 0.0019 18.3 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PRP83455.1 - 0.006 16.6 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family TFIIA PF03153.13 PRP83456.1 - 0.0013 18.9 31.3 0.0013 18.9 31.3 2.1 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit Baculo_PEP_C PF04513.12 PRP83456.1 - 4.7 7.3 17.1 4.9 7.2 1.5 3.9 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DnaJ PF00226.31 PRP83458.1 - 3.1e-20 72.0 0.2 4.4e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 PRP83458.1 - 8.5e-15 54.2 0.8 1.3e-14 53.6 0.8 1.3 1 0 0 1 1 1 1 CSL zinc finger PM0188 PF11477.8 PRP83458.1 - 0.0024 17.1 0.0 0.0029 16.8 0.0 1.0 1 0 0 1 1 1 1 Sialyltransferase PMO188 Endonuclease_NS PF01223.23 PRP83459.1 - 1.9e-59 201.2 0.0 2.9e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 PRP83459.1 - 0.12 12.5 0.0 0.59 10.2 0.0 2.0 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease PI-PLC-X PF00388.19 PRP83460.1 - 3.3e-58 195.4 0.0 6.8e-58 194.4 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PRP83460.1 - 2e-35 121.6 0.0 5.9e-35 120.1 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 PRP83460.1 - 3.7e-11 43.3 0.0 1.2e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 PRP83460.1 - 6.2e-09 36.1 0.0 1.7e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain PGBA_C PF15437.6 PRP83460.1 - 9 6.7 26.1 34 4.9 26.1 2.0 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal RRM_1 PF00076.22 PRP83461.1 - 5.3e-20 71.0 0.0 8e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP83461.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.24 PRP83462.1 - 1.4e-20 74.0 0.7 1.4e-20 74.0 0.7 4.5 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 LRR_9 PF14580.6 PRP83462.1 - 2.2e-06 27.3 0.0 2.2e-06 27.3 0.0 2.7 3 0 0 3 3 3 1 Leucine-rich repeat LRR_8 PF13855.6 PRP83462.1 - 0.023 14.4 0.1 0.082 12.7 0.0 1.9 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 PRP83462.1 - 0.07 13.6 0.0 0.66 10.5 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) RVT_1 PF00078.27 PRP83463.1 - 0.041 13.4 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) BRCT_2 PF16589.5 PRP83464.1 - 2.5e-06 27.8 0.0 0.00072 19.9 0.0 3.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 PRP83464.1 - 1.3e-05 25.0 0.0 1.3e-05 25.0 0.0 4.3 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 PRP83464.1 - 0.0039 17.6 0.1 0.049 14.0 0.0 3.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PRP83464.1 - 0.097 12.6 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain DUF4250 PF14056.6 PRP83464.1 - 0.52 10.3 3.7 1.5 8.8 0.5 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) DUF1899 PF08953.11 PRP83466.1 - 2.5e-18 65.7 0.0 6.9e-18 64.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 PRP83466.1 - 1.3e-13 50.6 0.5 2.6e-13 49.6 0.5 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 PRP83466.1 - 9.9e-10 38.9 0.6 0.0004 21.1 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP83466.1 - 2.5e-07 30.9 0.0 0.027 14.8 0.0 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP83466.1 - 0.0045 16.0 0.0 1.5 7.7 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PP2C PF00481.21 PRP83467.1 - 3.4e-49 167.8 0.0 4.1e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 PRP83467.1 - 2.5e-23 81.6 8.4 1.7e-10 40.5 0.1 3.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PRP83467.1 - 5.6e-13 48.8 1.8 1.5e-07 31.6 0.1 3.4 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP83467.1 - 1.3e-06 28.1 5.3 0.47 11.2 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP83467.1 - 2.5e-05 24.0 8.3 0.097 12.8 0.1 4.8 5 0 0 5 5 5 2 Leucine Rich repeat PP2C_2 PF13672.6 PRP83467.1 - 0.00013 21.7 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 PRP83467.1 - 0.00017 21.2 0.6 0.00025 20.6 0.6 1.3 1 0 0 1 1 1 1 Leucine-rich repeat SpoIIE PF07228.12 PRP83467.1 - 0.012 15.6 0.1 0.049 13.6 0.1 2.0 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) LRR_5 PF13306.6 PRP83467.1 - 0.016 15.2 0.2 0.027 14.4 0.2 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) RT_RNaseH PF17917.1 PRP83468.1 - 1.4e-34 118.5 0.1 2.6e-34 117.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP83468.1 - 6.6e-33 112.7 0.1 5.8e-32 109.7 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP83468.1 - 4.9e-21 74.6 0.1 9.7e-21 73.6 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP83468.1 - 3e-12 46.8 3.4 1.4e-11 44.6 0.1 3.0 4 0 0 4 4 4 1 Integrase core domain RVT_1 PF00078.27 PRP83468.1 - 4.5e-11 42.7 0.1 2.8e-09 36.8 0.0 2.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 PRP83468.1 - 1.3e-07 31.4 0.9 3.9e-07 29.9 0.9 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 PRP83468.1 - 3.1e-06 27.3 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 H2C2 zinc finger TPR_MLP1_2 PF07926.12 PRP83468.1 - 1.2 9.2 3.9 0.65 10.1 0.4 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nse4-Nse3_bdg PF15412.6 PRP83469.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Pkinase_Tyr PF07714.17 PRP83471.1 - 8.5e-75 251.4 0.0 1.2e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83471.1 - 8.8e-51 172.8 0.0 1.3e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP83471.1 - 1e-27 95.6 84.7 1.9e-06 27.5 6.2 15.2 13 2 3 16 16 16 9 Leucine rich repeat LRR_4 PF12799.7 PRP83471.1 - 9.8e-24 83.1 99.4 0.0002 21.7 1.7 16.9 9 5 8 19 19 19 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP83471.1 - 8.8e-09 34.7 55.6 2.2 8.5 0.3 20.3 24 0 0 24 24 23 3 Leucine Rich repeat LRRNT_2 PF08263.12 PRP83471.1 - 3.2e-05 24.2 0.9 0.00022 21.5 0.1 2.6 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain Kdo PF06293.14 PRP83471.1 - 0.00035 20.0 0.1 0.00063 19.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP83471.1 - 0.0035 16.7 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP83471.1 - 0.0045 15.8 0.2 0.0071 15.2 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase LRR_9 PF14580.6 PRP83471.1 - 0.017 14.6 9.4 0.082 12.4 0.4 3.7 3 0 0 3 3 3 0 Leucine-rich repeat TFIID-31kDa PF02291.15 PRP83471.1 - 0.024 14.7 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Haspin_kinase PF12330.8 PRP83471.1 - 0.072 12.0 0.7 0.44 9.4 0.1 2.1 2 0 0 2 2 2 0 Haspin like kinase domain SKG6 PF08693.10 PRP83471.1 - 0.082 12.3 2.1 0.18 11.3 2.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_1 PF00560.33 PRP83471.1 - 0.15 12.7 73.1 5.3 8.0 0.0 21.7 23 3 1 24 24 22 0 Leucine Rich Repeat DUF3827 PF12877.7 PRP83471.1 - 0.25 9.7 0.8 0.39 9.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Suppressor_P21 PF11479.8 PRP83471.1 - 2.4 8.4 6.7 1.1e+02 3.1 0.1 5.2 5 0 0 5 5 5 0 RNA silencing suppressor P21 C-terminal domain DSPc PF00782.20 PRP83472.1 - 2.7e-26 92.0 0.0 3e-25 88.6 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CH PF00307.31 PRP83472.1 - 3e-08 33.8 0.0 7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain Y_phosphatase PF00102.27 PRP83472.1 - 0.017 14.7 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pro-NT_NN PF07421.11 PRP83472.1 - 0.033 14.5 0.5 0.092 13.0 0.0 2.0 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor PTPlike_phytase PF14566.6 PRP83472.1 - 0.062 13.4 0.2 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate CDKN3 PF05706.12 PRP83472.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) IBR PF01485.21 PRP83473.1 - 5e-14 52.3 41.4 1.1e-08 35.2 8.1 3.3 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RAG1 PF10426.9 PRP83473.1 - 0.15 12.2 2.0 4.4 7.5 0.1 2.7 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain HhH-GPD PF00730.25 PRP83474.1 - 8.6e-13 48.7 0.0 1.3e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.9 PRP83474.1 - 0.038 14.3 1.3 0.089 13.2 1.3 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III TMF_TATA_bd PF12325.8 PRP83474.1 - 0.061 13.5 0.3 5.8 7.2 0.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4269 PF14091.6 PRP83474.1 - 0.089 13.0 0.0 0.2 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) DUF2004 PF09406.10 PRP83474.1 - 0.11 12.8 0.1 0.29 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) RasGEF PF00617.19 PRP83476.1 - 2.5e-38 132.0 2.4 2.6e-38 132.0 0.2 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP83476.1 - 0.0041 17.3 2.5 0.018 15.3 0.2 2.8 2 1 0 2 2 2 1 RasGEF N-terminal motif IQ PF00612.27 PRP83476.1 - 0.6 10.1 9.6 2.8 8.0 2.1 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif MMR_HSR1_Xtn PF16897.5 PRP83477.1 - 5.5e-41 138.9 0.3 1.1e-39 134.7 0.1 2.4 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 PRP83477.1 - 4.3e-24 84.3 0.1 8.6e-24 83.4 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 PRP83477.1 - 1.5e-16 60.5 0.0 3.1e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP83477.1 - 9e-06 25.3 0.1 4.6e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 Ferrous iron transport protein B F-box-like PF12937.7 PRP83477.1 - 0.00037 20.3 0.4 0.00037 20.3 0.4 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP83477.1 - 0.0062 16.4 2.3 0.021 14.7 0.1 2.9 3 0 0 3 3 3 1 F-box domain MeaB PF03308.16 PRP83477.1 - 0.01 14.8 0.2 0.021 13.8 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MyTH4 PF00784.17 PRP83477.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 MyTH4 domain Btz PF09405.10 PRP83478.1 - 4.5e-13 49.6 5.2 4.5e-13 49.6 5.2 4.4 2 1 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding ThiF PF00899.21 PRP83480.1 - 1.1e-64 218.1 0.0 1.7e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 PRP83480.1 - 2.4e-14 53.7 0.0 3.5e-13 50.0 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 PRP83480.1 - 0.0039 17.2 0.3 0.12 12.4 0.0 2.4 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase DivIC PF04977.15 PRP83480.1 - 0.013 15.2 0.4 0.031 14.0 0.4 1.6 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 PRP83480.1 - 0.029 14.4 0.3 0.029 14.4 0.3 1.9 2 0 0 2 2 2 0 Basic region leucine zipper PspB PF06667.12 PRP83480.1 - 0.052 13.6 0.7 0.13 12.4 0.7 1.6 1 0 0 1 1 1 0 Phage shock protein B Git3 PF11710.8 PRP83481.1 - 8.4e-08 32.2 14.6 1.8e-07 31.2 14.6 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 PRP83481.1 - 2.3e-06 26.9 12.4 2.8e-06 26.7 12.4 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 PRP83481.1 - 2.9e-05 23.5 13.5 4.4e-05 23.0 13.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 PRP83481.1 - 0.0011 18.2 16.6 0.0019 17.5 15.8 1.8 1 1 0 1 1 1 1 Pheromone A receptor 7tm_2 PF00002.24 PRP83481.1 - 0.0021 17.4 15.2 0.0041 16.5 14.3 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 PRP83481.1 - 0.0036 17.3 7.1 0.0039 17.2 0.1 3.0 2 1 1 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3671 PF12420.8 PRP83481.1 - 2.3 8.4 11.9 1.5 8.9 4.3 3.0 1 1 2 3 3 3 0 Protein of unknown function zf-ANAPC11 PF12861.7 PRP83482.1 - 1.7e-07 31.2 5.0 4e-07 30.0 5.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PRP83482.1 - 1.4e-05 25.3 6.6 3.3e-05 24.1 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain ADH_zinc_N PF00107.26 PRP83483.1 - 1.4e-22 80.1 0.0 2.2e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP83483.1 - 5.1e-19 69.6 0.0 8.2e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP83483.1 - 4.4e-07 29.8 0.1 2.2e-06 27.5 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 PRP83483.1 - 0.078 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Ras PF00071.22 PRP83484.1 - 3.1e-35 121.2 0.2 3.7e-35 120.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP83484.1 - 6.5e-26 90.9 0.1 1.1e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP83484.1 - 5.2e-08 32.5 0.0 6.7e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP83484.1 - 3.5e-06 26.5 0.2 4.5e-06 26.2 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 PRP83484.1 - 0.01 14.7 0.4 1 8.1 0.0 2.1 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 PRP83484.1 - 0.043 13.0 1.2 0.093 11.9 0.2 2.0 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 PRP83484.1 - 0.06 13.1 0.4 0.13 12.1 0.4 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 PRP83484.1 - 0.087 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PRP83484.1 - 0.095 12.8 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase NadA PF02445.16 PRP83484.1 - 0.099 11.8 0.1 6.5 5.8 0.0 2.0 2 0 0 2 2 2 0 Quinolinate synthetase A protein TniB PF05621.11 PRP83484.1 - 0.19 11.1 0.1 2.5 7.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein GDI PF00996.18 PRP83485.1 - 1.5e-55 188.5 0.9 3e-41 141.4 0.2 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Connexin PF00029.19 PRP83485.1 - 0.88 9.3 5.5 1.7 8.3 0.2 2.4 2 0 0 2 2 2 0 Connexin PA14 PF07691.12 PRP83486.1 - 4.4e-12 46.0 0.0 8.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 PRP83486.1 - 0.11 12.4 234.0 0.025 14.5 18.5 18.3 17 0 0 17 17 17 0 Dictyostelium (slime mold) repeat Bacteriocin_IIc PF10439.9 PRP83486.1 - 2 8.6 12.4 5.4 7.2 12.4 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide COesterase PF00135.28 PRP83487.1 - 2.1e-75 254.6 0.0 3e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP83487.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PRP83488.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 PRP83488.1 - 0.00084 19.1 1.5 0.0017 18.1 1.5 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 PRP83488.1 - 0.0074 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 PRP83488.1 - 0.016 14.7 0.0 0.098 12.1 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 PRP83488.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Epimerase PF01370.21 PRP83489.1 - 1.1e-24 87.3 0.0 1.7e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PRP83489.1 - 1e-17 64.0 0.0 1.3e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PRP83489.1 - 2.9e-13 50.0 0.0 3.3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PRP83489.1 - 4.1e-13 49.6 0.1 7.1e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PRP83489.1 - 4.7e-13 48.9 0.1 1.3e-12 47.4 0.1 1.8 2 1 0 2 2 2 1 Male sterility protein KR PF08659.10 PRP83489.1 - 2.5e-08 34.0 0.3 4.7e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 PRP83489.1 - 2.4e-06 27.3 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 PRP83489.1 - 0.00034 20.1 0.2 0.0021 17.5 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 PRP83489.1 - 0.061 12.4 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CH PF00307.31 PRP83490.1 - 2e-13 50.4 0.0 1.2e-12 48.0 0.0 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain GAS2 PF02187.17 PRP83490.1 - 2.2e-07 30.8 0.1 2.2e-07 30.8 0.1 4.1 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain DUF155 PF02582.14 PRP83491.1 - 4.3e-29 101.8 0.3 2.3e-26 92.9 0.3 2.9 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 V-ATPase_G PF03179.15 PRP83491.1 - 7.5e-22 77.9 12.1 7.5e-22 77.9 12.1 2.2 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit Ank_2 PF12796.7 PRP83491.1 - 6.7e-14 52.3 0.1 0.00031 21.3 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP83491.1 - 0.0001 22.4 0.2 1.6 9.5 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 PRP83491.1 - 0.0024 18.2 3.5 16 6.2 0.1 5.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 PRP83491.1 - 0.004 17.4 0.4 4.6 7.7 0.1 4.9 3 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP83491.1 - 0.012 16.2 0.5 4.3 8.0 0.2 4.0 4 1 0 4 4 4 0 Ankyrin repeats (many copies) DUF3135 PF11333.8 PRP83491.1 - 0.15 12.3 1.1 0.39 11.0 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) V-ATPase_G_2 PF16999.5 PRP83491.1 - 1.1 9.7 12.2 3 8.3 12.2 1.8 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Glyco_transf_54 PF04666.13 PRP83492.1 - 3e-13 49.3 0.0 8.2e-06 24.9 0.0 3.0 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Acetyltransf_1 PF00583.25 PRP83492.1 - 1.7e-10 41.2 0.0 5.5e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP83492.1 - 3.5e-05 23.7 0.1 8.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP83492.1 - 0.00029 21.2 0.0 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_His PF13393.6 PRP83493.1 - 1.1e-42 146.4 0.0 1.5e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 PRP83493.1 - 8e-13 48.4 0.2 1.8e-12 47.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 PRP83493.1 - 0.00035 19.7 0.1 0.003 16.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 PRP83493.1 - 0.0095 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs Creatinase_N_2 PF16189.5 PRP83494.1 - 1.2e-50 171.7 0.0 3.1e-50 170.4 0.0 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 PRP83494.1 - 3.3e-46 157.6 0.0 4.7e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 PRP83494.1 - 1.2e-25 89.3 0.1 4.8e-24 84.2 0.0 2.9 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 PRP83494.1 - 3.4e-20 73.0 0.0 6.6e-15 55.9 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Abhydrolase_3 PF07859.13 PRP83495.1 - 6.1e-26 91.6 0.0 1.9e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PRP83495.1 - 9.3e-08 31.3 0.0 1.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase bZIP_1 PF00170.21 PRP83495.1 - 0.00062 19.8 10.2 0.0028 17.7 10.2 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PRP83495.1 - 0.0057 16.7 8.9 0.051 13.7 8.9 2.2 1 1 0 1 1 1 1 Basic region leucine zipper BRE1 PF08647.11 PRP83495.1 - 0.049 13.7 3.4 0.094 12.8 3.4 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF3972 PF13118.6 PRP83495.1 - 0.072 13.5 0.6 0.16 12.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) bZIP_Maf PF03131.17 PRP83495.1 - 0.1 13.2 2.9 0.21 12.1 2.9 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Ribosomal_L27A PF00828.19 PRP83496.1 - 6.1e-24 85.1 0.0 9.1e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SIR2 PF02146.17 PRP83497.1 - 5.3e-58 195.8 0.0 1.1e-57 194.9 0.0 1.5 1 0 0 1 1 1 1 Sir2 family zf-UBP PF02148.19 PRP83497.1 - 7.5e-20 71.0 11.5 7.5e-20 71.0 11.5 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-dskA_traR PF01258.17 PRP83497.1 - 1.7 8.6 6.0 6.4 6.8 0.1 3.8 3 1 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger zf-piccolo PF05715.13 PRP83497.1 - 4.3 7.6 7.0 0.78 9.9 1.4 2.4 3 0 0 3 3 3 0 Piccolo Zn-finger Zn_Tnp_IS91 PF14319.6 PRP83497.1 - 8.9 6.4 11.2 17 5.5 4.8 2.7 2 1 1 3 3 3 0 Transposase zinc-binding domain Isochorismatase PF00857.20 PRP83498.1 - 6.9e-32 111.0 0.0 1e-31 110.5 0.0 1.2 1 1 0 1 1 1 1 Isochorismatase family Avl9 PF09794.9 PRP83499.1 - 9.4e-86 287.9 0.3 6.1e-84 281.9 0.3 2.1 1 1 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 PRP83499.1 - 2.9e-08 33.7 0.7 1.3e-05 24.9 0.7 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 PRP83499.1 - 0.0088 16.5 0.1 0.021 15.3 0.1 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking CarboxypepD_reg PF13620.6 PRP83501.1 - 5.4e-10 39.4 0.2 1.8e-09 37.8 0.2 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PRP83501.1 - 2.3e-08 33.9 0.0 5.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 CarboxypepD_reg-like domain TIG PF01833.24 PRP83501.1 - 5.6e-08 32.8 12.3 0.00016 21.7 0.6 3.5 3 0 0 3 3 3 2 IPT/TIG domain MBG_2 PF18676.1 PRP83501.1 - 0.0062 17.1 1.2 0.018 15.6 0.2 2.3 2 0 0 2 2 2 1 MBG domain (YGX type) fn3_3 PF14686.6 PRP83501.1 - 0.017 14.9 0.0 0.062 13.1 0.0 1.9 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II MINDY_DUB PF04424.13 PRP83502.1 - 1.5e-30 105.6 0.1 3.2e-30 104.6 0.1 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase MORN PF02493.20 PRP83502.1 - 8.5e-25 85.1 40.1 3.6e-06 26.5 2.8 7.3 7 0 0 7 7 7 5 MORN repeat F-box PF00646.33 PRP83502.1 - 4e-10 39.3 1.6 7.6e-10 38.4 1.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP83502.1 - 5.5e-10 39.0 1.4 1e-09 38.1 1.4 1.5 1 0 0 1 1 1 1 F-box-like Tudor_2 PF18104.1 PRP83502.1 - 0.063 13.0 11.1 0.13 12.0 0.2 5.5 6 0 0 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain DUF4091 PF13320.6 PRP83502.1 - 6.1 7.1 6.8 1.2 9.4 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4091) LRR_9 PF14580.6 PRP83503.1 - 6e-09 35.6 0.5 1.4e-08 34.4 0.5 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PRP83503.1 - 2.5e-08 34.1 19.6 0.00011 22.5 2.4 3.8 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) TIG PF01833.24 PRP83503.1 - 0.00016 21.7 0.1 0.00031 20.8 0.1 1.5 1 0 0 1 1 1 1 IPT/TIG domain LRR_8 PF13855.6 PRP83503.1 - 0.00075 19.2 14.8 0.015 15.1 4.2 3.6 2 1 0 3 3 3 2 Leucine rich repeat Glyco_hydro_18 PF00704.28 PRP83504.1 - 1.1e-63 215.8 7.9 1.4e-63 215.5 7.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP83504.1 - 9.1e-08 32.5 19.5 2.6e-07 31.0 19.5 1.8 1 0 0 1 1 1 1 Chitin recognition protein DUF2755 PF10954.8 PRP83505.1 - 0.053 13.4 3.3 0.13 12.2 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) PQ-loop PF04193.14 PRP83506.1 - 4.8e-21 74.3 13.4 2.8e-11 43.0 3.3 2.7 2 0 0 2 2 2 2 PQ loop repeat 7TMR-HDED PF07697.11 PRP83506.1 - 0.41 10.7 0.9 0.64 10.1 0.9 1.2 1 0 0 1 1 1 0 7TM-HD extracellular HEAT_2 PF13646.6 PRP83508.1 - 1.3e-08 35.1 3.3 0.0097 16.3 0.1 4.9 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 PRP83508.1 - 1.2e-06 28.2 6.8 0.19 12.1 0.1 7.0 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.20 PRP83508.1 - 3.1e-06 26.0 6.3 0.00021 20.0 0.1 2.5 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 PRP83508.1 - 4.9e-05 23.4 12.0 0.0098 15.9 0.2 5.8 5 2 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 PRP83508.1 - 0.00013 21.7 5.2 0.0005 19.7 0.5 3.4 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 PRP83508.1 - 0.0035 17.5 0.2 0.35 11.0 0.1 3.9 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 PRP83508.1 - 0.022 14.7 0.6 2.1 8.3 0.1 3.9 3 1 0 3 3 3 0 Myosin-binding striated muscle assembly central U3snoRNP10 PF12397.8 PRP83508.1 - 0.031 14.6 0.3 0.43 10.9 0.0 3.1 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 PRP83508.1 - 0.038 14.5 1.1 4.2 8.0 0.1 3.9 3 0 0 3 3 3 0 HEAT-like repeat NCD3G PF07562.14 PRP83508.1 - 1 9.4 3.9 2.4 8.2 3.9 1.6 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR VPS9 PF02204.18 PRP83509.1 - 1.3e-15 57.5 0.1 3.2e-15 56.2 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 PRP83509.1 - 6.8e-10 39.0 2.8 1.8e-08 34.4 2.0 3.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Peptidase_S9 PF00326.21 PRP83509.1 - 4.1e-06 26.4 0.1 9.8e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 PRP83509.1 - 0.00027 20.5 0.0 0.00067 19.2 0.0 1.6 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 PRP83509.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase YL1 PF05764.13 PRP83509.1 - 0.0083 16.3 2.1 0.0083 16.3 2.1 3.3 3 0 0 3 3 3 1 YL1 nuclear protein AXE1 PF05448.12 PRP83509.1 - 0.026 13.2 0.3 0.43 9.2 0.0 2.6 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) He_PIG_assoc PF10632.9 PRP83509.1 - 0.045 13.4 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Pkinase_Tyr PF07714.17 PRP83510.1 - 1.6e-54 185.0 0.0 2.8e-54 184.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83510.1 - 2.7e-35 122.0 0.0 5.9e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain RasGAP PF00616.19 PRP83510.1 - 8.9e-14 51.7 0.3 2.3e-12 47.1 0.2 5.1 4 3 1 5 5 5 2 GTPase-activator protein for Ras-like GTPase TMEM154 PF15102.6 PRP83510.1 - 0.00098 19.0 0.9 0.00098 19.0 0.9 17.2 2 1 7 9 9 9 1 TMEM154 protein family SKG6 PF08693.10 PRP83510.1 - 0.051 13.0 4.6 0.45 10.0 4.6 2.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PRP83510.1 - 0.081 13.8 1.0 0.35 11.8 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Replicase PF03090.17 PRP83510.1 - 0.097 12.5 0.2 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 Replicase family DUF3377 PF11857.8 PRP83510.1 - 0.098 12.6 3.9 0.085 12.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Kinase-like PF14531.6 PRP83510.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_18 PF00704.28 PRP83511.1 - 3.6e-63 214.2 7.7 4.2e-63 214.0 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP83511.1 - 1.7e-08 34.8 25.2 4.3e-08 33.5 25.2 1.7 1 0 0 1 1 1 1 Chitin recognition protein nec1 PF10379.9 PRP83511.1 - 1.1 8.8 4.2 3.3 7.2 4.2 1.8 1 0 0 1 1 1 0 Virulence protein nec1 FA_desaturase PF00487.24 PRP83512.1 - 7.2e-17 62.1 24.5 1.1e-16 61.5 24.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 PRP83512.1 - 1.8e-12 47.2 0.0 4.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Dehydratase_hem PF13816.6 PRP83512.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Haem-containing dehydratase DUF1189 PF06691.11 PRP83512.1 - 0.13 11.9 2.0 0.24 10.9 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) RasGEF PF00617.19 PRP83513.1 - 1.5e-44 152.3 0.7 4.7e-44 150.7 0.2 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP83513.1 - 1.9e-13 50.5 2.2 4.2e-13 49.4 0.4 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif FERM_f0 PF16511.5 PRP83513.1 - 9.4e-08 32.3 0.1 0.058 13.7 0.0 4.4 4 1 0 4 4 4 2 N-terminal or F0 domain of Talin-head FERM Drf_GBD PF06371.13 PRP83513.1 - 2.5e-07 30.5 0.3 8.3e-07 28.8 0.3 1.9 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 PRP83513.1 - 5.1e-05 23.0 4.8 8.2e-05 22.3 2.3 2.5 3 0 0 3 3 3 1 Diaphanous FH3 Domain DHHC PF01529.20 PRP83515.1 - 6.1e-24 84.6 37.3 1.9e-18 66.8 11.4 3.4 3 1 0 3 3 3 2 DHHC palmitoyltransferase zf-ribbon_3 PF13248.6 PRP83515.1 - 0.099 12.1 4.8 0.29 10.6 4.8 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.7 PRP83515.1 - 1.1 9.3 9.1 3.2 7.9 9.1 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF872 PF05915.12 PRP83515.1 - 1.6 9.0 7.8 9.1 6.5 4.2 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4131 PF13567.6 PRP83515.1 - 3.6 7.2 6.5 5.1 6.7 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) zinc_ribbon_2 PF13240.6 PRP83515.1 - 7.3 6.4 7.2 2.3 8.0 4.0 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Nup35_RRM PF05172.13 PRP83517.1 - 0.0012 18.8 0.0 0.0037 17.2 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 PRP83517.1 - 0.0034 17.3 0.1 0.0068 16.4 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 PRP83517.1 - 0.024 14.6 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 RL domain LMBR1 PF04791.16 PRP83518.1 - 3.8 6.3 10.3 6.9 5.5 10.3 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein Usp PF00582.26 PRP83520.1 - 2.1e-25 89.9 0.0 3e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family BPL_LplA_LipB PF03099.19 PRP83521.1 - 1.1e-08 35.0 0.0 2.8e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 PRP83521.1 - 4.5e-07 29.8 0.0 7.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus zf-RING_2 PF13639.6 PRP83523.1 - 7.4e-14 51.8 7.3 7.4e-14 51.8 7.3 2.2 2 0 0 2 2 2 1 Ring finger domain zinc_ribbon_9 PF14369.6 PRP83523.1 - 1.4e-11 44.4 1.1 1.4e-11 44.4 1.1 2.1 2 0 0 2 2 2 1 zinc-ribbon zf-RING_11 PF17123.5 PRP83523.1 - 5.1e-10 38.9 2.3 5.1e-10 38.9 2.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PRP83523.1 - 3.8e-09 36.4 1.7 3.8e-09 36.4 1.7 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP83523.1 - 5.4e-09 35.8 7.6 5.4e-09 35.8 7.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP83523.1 - 3.9e-08 33.0 13.4 2.8e-07 30.3 5.8 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP83523.1 - 1.1e-07 32.0 9.6 1.1e-07 32.0 9.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PRP83523.1 - 7.5e-07 28.9 8.7 7.5e-07 28.9 8.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP83523.1 - 1.5e-05 24.8 6.0 1.5e-05 24.8 6.0 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP83523.1 - 4.6e-05 23.3 16.4 0.0001 22.2 7.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PRP83523.1 - 0.00041 19.9 5.5 0.00041 19.9 5.5 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 PRP83523.1 - 0.0025 17.8 6.0 0.0025 17.8 6.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 PRP83523.1 - 0.0028 17.5 0.9 0.061 13.2 0.0 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C3H2C3 PF17122.5 PRP83523.1 - 0.011 15.7 6.8 0.011 15.7 6.8 2.3 2 0 0 2 2 2 0 Zinc-finger zf-Nse PF11789.8 PRP83523.1 - 0.016 15.0 4.3 0.016 15.0 4.3 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 PRP83523.1 - 0.024 15.0 6.7 0.024 15.0 6.7 2.5 2 1 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.6 PRP83523.1 - 0.029 14.3 11.3 0.7 9.9 1.6 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 PRP83523.1 - 0.038 14.1 0.4 0.038 14.1 0.4 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Baculo_RING PF05883.11 PRP83523.1 - 0.068 13.2 0.8 0.15 12.1 0.8 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain HypA PF01155.19 PRP83523.1 - 0.098 12.7 0.6 0.098 12.7 0.6 2.5 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 PRP83523.1 - 0.12 12.4 10.7 0.17 11.9 1.0 3.0 2 1 0 2 2 2 0 Double zinc ribbon DUF983 PF06170.12 PRP83523.1 - 0.21 12.0 2.2 2.4 8.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) zf-RING_4 PF14570.6 PRP83523.1 - 0.36 10.6 16.0 6 6.7 1.7 3.0 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-TFIIB PF13453.6 PRP83523.1 - 0.47 9.8 6.6 6.8 6.1 1.8 2.9 2 1 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_16 PF17034.5 PRP83523.1 - 0.56 10.4 8.0 3.6 7.8 4.6 2.6 2 1 0 2 2 2 0 Zinc-ribbon like family LIM PF00412.22 PRP83523.1 - 0.79 10.0 9.3 6.7 7.0 3.2 3.0 2 1 0 2 2 2 0 LIM domain DUF1272 PF06906.11 PRP83523.1 - 0.92 9.6 11.2 1.2 9.2 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zf-ribbon_3 PF13248.6 PRP83523.1 - 2.7 7.5 7.4 7 6.2 0.6 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 PRP83523.1 - 3.7 7.6 12.6 3.3 7.7 0.8 2.9 2 1 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS91 PF14319.6 PRP83523.1 - 3.7 7.6 9.3 1.8 8.7 0.5 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain RINGv PF12906.7 PRP83523.1 - 5.4 7.2 14.8 0.049 13.8 5.9 2.1 2 1 0 2 2 1 0 RING-variant domain C1_1 PF00130.22 PRP83523.1 - 6.1 6.8 15.9 4.5 7.2 1.5 3.2 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-P11 PF03854.14 PRP83523.1 - 8 6.2 13.9 5.5 6.7 8.4 2.6 2 1 0 2 2 2 0 P-11 zinc finger Cyd_oper_YbgE PF09600.10 PRP83526.1 - 0.026 14.9 1.1 0.41 11.0 0.2 2.3 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Fascin PF06268.13 PRP83527.1 - 3.6e-10 40.1 0.1 1.7e-09 37.8 0.1 1.9 1 1 0 1 1 1 1 Fascin domain FRG1 PF06229.12 PRP83527.1 - 3.7e-06 26.8 0.2 0.11 12.2 0.1 2.5 1 1 2 3 3 3 2 FRG1-like domain FGF PF00167.18 PRP83527.1 - 0.00019 21.5 0.1 0.018 15.1 0.1 2.1 1 1 1 2 2 2 2 Fibroblast growth factor Ank_3 PF13606.6 PRP83528.1 - 1.1e-13 50.0 0.1 0.0007 19.9 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 PRP83528.1 - 2.8e-13 50.3 0.1 6.2e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) BTB PF00651.31 PRP83528.1 - 2.7e-12 46.9 0.4 6.9e-12 45.6 0.4 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.6 PRP83528.1 - 1e-10 41.9 0.5 0.00017 22.1 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP83528.1 - 7.1e-10 38.9 1.9 0.021 15.2 0.1 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PRP83528.1 - 7.8e-07 29.3 0.0 0.061 13.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) COX2 PF00116.20 PRP83531.1 - 1.6e-07 31.3 0.1 2.6e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 PRP83531.1 - 0.0026 17.9 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Proton_antipo_M PF00361.20 PRP83533.1 - 1e-108 363.0 17.6 2.2e-54 184.7 4.9 2.8 2 0 0 2 2 2 2 Proton-conducting membrane transporter COX2 PF00116.20 PRP83533.1 - 1e-80 267.4 0.0 2e-48 163.2 0.0 2.6 2 0 0 2 2 2 2 Cytochrome C oxidase subunit II, periplasmic domain Oxidored_q2 PF00420.24 PRP83533.1 - 4.4e-12 45.6 40.5 1.1e-05 25.0 5.9 4.5 5 0 0 5 5 5 3 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4491 PF14898.6 PRP83533.1 - 0.05 14.1 0.7 43 4.6 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4491) CDP-OH_P_transf PF01066.21 PRP83533.1 - 0.075 13.8 10.2 4.9 8.0 0.8 5.0 3 2 0 3 3 3 0 CDP-alcohol phosphatidyltransferase Proton_antipo_M PF00361.20 PRP83535.1 - 6.8e-161 534.3 58.6 7.6e-66 222.3 14.9 4.4 3 1 1 4 4 4 4 Proton-conducting membrane transporter Oxidored_q5_N PF01059.17 PRP83535.1 - 1.5e-11 44.4 9.1 0.0089 16.1 0.1 4.5 4 0 0 4 4 4 3 NADH-ubiquinone oxidoreductase chain 4, amino terminus FtsL PF04999.13 PRP83535.1 - 1.6 8.8 5.0 1.5e+02 2.5 0.1 4.2 3 0 0 3 3 3 0 Cell division protein FtsL Rbx_binding PF18113.1 PRP83535.1 - 8 6.3 13.3 34 4.3 0.6 3.7 3 0 0 3 3 3 0 Rubredoxin binding C-terminal domain Cuticle_2 PF08184.11 PRP83536.1 - 0.24 11.5 2.4 1.7e+02 2.3 0.0 4.4 4 0 0 4 4 4 0 Cuticle protein 7 isoform family Cytochrome_B PF00033.19 PRP83537.1 - 3.7e-70 235.6 16.8 8e-70 234.5 16.8 1.5 1 0 0 1 1 1 1 Cytochrome b/b6/petB ATP-synt_ab PF00006.25 PRP83537.1 - 2.9e-67 226.5 0.0 4.3e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Cytochrom_B_C PF00032.17 PRP83537.1 - 6.6e-60 199.8 20.2 6.9e-31 106.6 3.8 3.1 3 0 0 3 3 2 2 Cytochrome b(C-terminal)/b6/petD ATP-synt_ab_C PF00306.27 PRP83537.1 - 9.4e-36 122.9 0.0 1.8e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Cytochrom_B_N_2 PF13631.6 PRP83537.1 - 1.3e-31 109.8 14.0 1.3e-31 109.8 14.0 2.0 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Ribosom_S12_S23 PF00164.25 PRP83537.1 - 1.4e-14 53.7 0.1 3.1e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L2_C PF03947.18 PRP83537.1 - 3.1e-13 50.0 3.0 3.1e-13 50.0 3.0 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain ATP-synt_ab_N PF02874.23 PRP83537.1 - 7.6e-08 32.8 10.3 3.9e-07 30.5 2.8 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_C PF00137.21 PRP83537.1 - 3.2e-06 27.4 4.8 1.5e-05 25.2 4.8 2.2 1 0 0 1 1 1 1 ATP synthase subunit C Ribosomal_L11_N PF03946.14 PRP83537.1 - 1.9e-05 24.4 0.0 7.3e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain HAS-barrel PF09378.10 PRP83537.1 - 0.014 15.5 4.3 0.28 11.4 0.3 2.5 2 0 0 2 2 2 0 HAS barrel domain GerA PF03323.13 PRP83537.1 - 0.14 10.6 0.3 0.25 9.8 0.3 1.3 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Leu_Phe_trans PF03588.14 PRP83537.1 - 0.19 11.2 0.1 25 4.3 0.0 2.2 2 0 0 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase ATPase PF06745.13 PRP83537.1 - 0.29 10.5 0.0 0.44 9.9 0.0 1.2 1 0 0 1 1 1 0 KaiC Ribosomal_L16 PF00252.18 PRP83539.1 - 6.4e-06 26.2 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L14 PF00238.19 PRP83539.1 - 0.00037 20.6 0.0 0.00098 19.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e bPH_5 PF10882.8 PRP83539.1 - 0.14 12.3 2.8 13 6.0 0.2 2.5 2 0 0 2 2 2 0 Bacterial PH domain CbiN PF02553.15 PRP83541.1 - 3.3 7.8 3.9 1.7 8.7 1.0 1.9 1 1 1 2 2 2 0 Cobalt transport protein component CbiN p450 PF00067.22 PRP83543.1 - 2.1e-76 257.5 0.0 3.1e-76 257.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_17 PF00332.18 PRP83543.1 - 3.5e-11 43.3 0.7 1.1e-10 41.6 0.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 X8 PF07983.13 PRP83543.1 - 9.1e-08 32.7 3.3 2.2e-07 31.5 3.3 1.7 1 0 0 1 1 1 1 X8 domain F-box PF00646.33 PRP83544.1 - 3.2e-07 30.1 0.4 7.4e-07 28.9 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP83544.1 - 0.00012 21.9 3.2 0.00025 20.9 3.2 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 PRP83544.1 - 0.045 13.6 0.2 0.076 12.9 0.2 1.4 1 0 0 1 1 1 0 F-box Pkinase_Tyr PF07714.17 PRP83545.1 - 8.1e-48 162.9 0.0 1.2e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83545.1 - 4.8e-44 150.7 0.0 7.1e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kelch_1 PF01344.25 PRP83545.1 - 2.1e-05 24.0 11.5 0.014 14.9 0.2 5.6 5 0 0 5 5 5 2 Kelch motif DUF5122 PF17164.4 PRP83545.1 - 0.36 11.1 31.6 0.84 10.0 0.3 8.5 9 0 0 9 9 9 0 Domain of unknown function (DUF5122) beta-propeller Kelch_4 PF13418.6 PRP83545.1 - 0.44 10.6 7.7 0.91 9.6 0.1 4.9 5 1 1 6 6 6 0 Galactose oxidase, central domain Rax2 PF12768.7 PRP83545.1 - 1.3 8.5 11.0 1 8.8 0.3 4.8 5 1 0 5 5 5 0 Cortical protein marker for cell polarity Kelch_2 PF07646.15 PRP83545.1 - 2.6 8.2 17.6 5.1 7.2 0.1 7.6 10 0 0 10 10 10 0 Kelch motif LVIVD PF08309.11 PRP83545.1 - 5 6.5 10.6 3.9 6.9 0.4 3.7 3 0 0 3 3 3 0 LVIVD repeat Kelch_6 PF13964.6 PRP83545.1 - 9.5 6.7 11.8 2.5 8.5 0.1 5.2 5 0 0 5 5 5 0 Kelch motif F-box PF00646.33 PRP83546.1 - 2.1e-07 30.7 0.3 4.5e-07 29.6 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP83546.1 - 0.00017 21.4 1.4 0.0004 20.2 1.4 1.7 1 0 0 1 1 1 1 F-box-like ABC_tran PF00005.27 PRP83547.1 - 4.6e-18 66.0 0.0 3.1e-17 63.4 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 PRP83547.1 - 3.4e-05 23.4 0.0 0.043 13.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PRP83547.1 - 0.00075 19.2 0.0 0.0028 17.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP83547.1 - 0.0075 16.8 0.6 0.09 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP83547.1 - 0.0075 16.7 0.0 0.017 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 PRP83547.1 - 0.0088 15.9 0.1 0.018 14.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 PRP83547.1 - 0.058 12.6 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 PRP83547.1 - 0.097 13.2 0.3 0.78 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP83547.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 PRP83549.1 - 1.5e-60 204.7 1.3 3.3e-60 203.6 0.7 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP83549.1 - 3e-14 53.3 0.0 6.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FHA_2 PF17913.1 PRP83549.1 - 3.1e-10 40.2 0.0 7.1e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 PRP83549.1 - 3.8e-07 29.8 8.8 3.8e-07 29.8 8.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP83549.1 - 4.5e-07 30.1 9.2 8.9e-07 29.1 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PRP83549.1 - 6.6e-07 29.3 5.8 3.2e-06 27.1 5.8 2.2 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PRP83549.1 - 2e-06 27.6 7.3 5.2e-06 26.2 7.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PRP83549.1 - 3e-06 27.0 7.3 5.5e-06 26.1 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 PRP83549.1 - 5.8e-06 26.4 0.0 5.8e-06 26.4 0.0 2.8 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 PRP83549.1 - 8.2e-06 25.6 10.3 1.6e-05 24.7 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 PRP83549.1 - 2.6e-05 24.3 3.2 5.7e-05 23.2 3.2 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 PRP83549.1 - 4.6e-05 23.3 9.2 9e-05 22.4 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ERCC3_RAD25_C PF16203.5 PRP83549.1 - 0.0005 19.3 0.0 0.0017 17.7 0.0 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-rbx1 PF12678.7 PRP83549.1 - 0.00062 20.0 3.5 0.0023 18.2 3.5 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PRP83549.1 - 0.0056 16.8 10.9 0.011 15.8 10.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FHA PF00498.26 PRP83549.1 - 0.0087 16.4 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_6 PF14835.6 PRP83549.1 - 0.073 12.9 4.5 0.18 11.7 4.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PRP83549.1 - 0.17 11.7 2.6 0.51 10.2 2.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PRP83549.1 - 1.3 9.1 5.3 0.25 11.4 0.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 PRP83549.1 - 1.9 8.3 5.3 5.4 6.8 5.3 1.9 1 0 0 1 1 1 0 RING-like zinc finger Gin PF10764.9 PRP83549.1 - 3.1 7.8 5.2 8 6.5 5.2 1.8 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Ras PF00071.22 PRP83550.1 - 9.2e-39 132.6 3.8 8.5e-37 126.2 3.8 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP83550.1 - 1e-22 80.6 1.1 8.6e-21 74.4 1.1 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PRP83550.1 - 3.2e-06 27.2 0.1 0.058 13.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 PRP83550.1 - 3.1e-05 23.3 1.4 0.045 12.9 0.0 2.1 1 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PRP83550.1 - 7.2e-05 22.8 0.1 0.00015 21.8 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 PRP83550.1 - 0.0016 17.9 0.8 0.061 12.8 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 PRP83550.1 - 0.003 18.0 0.1 0.004 17.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 PRP83550.1 - 0.0061 15.8 0.0 0.037 13.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Septin PF00735.18 PRP83550.1 - 0.01 15.1 0.1 0.022 14.0 0.1 1.5 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 PRP83550.1 - 0.013 15.0 0.3 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 PRP83550.1 - 0.017 14.7 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 PRP83550.1 - 0.025 14.3 0.2 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Raf1_N PF18578.1 PRP83550.1 - 0.026 15.0 0.1 0.32 11.5 0.1 2.1 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain AAA_22 PF13401.6 PRP83550.1 - 0.033 14.5 0.1 0.081 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain VirE PF05272.11 PRP83550.1 - 0.046 13.4 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 Virulence-associated protein E TniB PF05621.11 PRP83550.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 PRP83550.1 - 0.077 12.3 0.9 0.16 11.3 0.9 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region NB-ARC PF00931.22 PRP83550.1 - 0.11 11.7 1.1 0.15 11.2 1.1 1.6 1 1 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 PRP83550.1 - 0.16 11.7 2.5 0.23 11.2 0.3 2.4 2 2 0 2 2 2 0 AAA domain Arf PF00025.21 PRP83551.1 - 8.7e-43 145.8 0.0 1.3e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PRP83551.1 - 9.5e-11 41.4 0.0 1.5e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PRP83551.1 - 1.4e-06 28.6 0.0 5.7e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PRP83551.1 - 2.6e-05 24.3 0.0 5.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PRP83551.1 - 6.1e-05 22.3 0.5 0.1 11.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 PRP83551.1 - 0.00017 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 PRP83551.1 - 0.0084 16.4 0.0 0.28 11.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 PRP83551.1 - 0.02 14.7 0.0 0.041 13.6 0.1 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 PRP83551.1 - 0.066 12.6 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_18 PF13238.6 PRP83551.1 - 0.066 13.8 0.0 0.095 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ACT PF01842.25 PRP83551.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain TFIIS_M PF07500.14 PRP83552.1 - 4.5e-22 78.7 0.8 1.1e-21 77.4 0.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 PRP83552.1 - 6.2e-11 42.0 8.7 1.2e-10 41.2 8.7 1.5 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 PRP83552.1 - 8.9e-08 32.2 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 SPOC domain CheX PF13690.6 PRP83552.1 - 0.0054 16.9 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 Chemotaxis phosphatase CheX zf-PHD-like PF15446.6 PRP83552.1 - 0.0076 15.9 5.1 0.0076 15.9 5.1 1.8 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain EMP24_GP25L PF01105.24 PRP83553.1 - 1.9e-33 115.9 0.0 2.3e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD zf-RING_2 PF13639.6 PRP83554.1 - 7.4e-10 39.0 9.9 1.5e-09 38.0 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP83554.1 - 3.8e-09 36.2 9.4 7.5e-09 35.3 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP83554.1 - 8.3e-08 32.0 10.0 1.5e-07 31.2 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP83554.1 - 2.4e-07 30.5 10.1 3.6e-07 29.9 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP83554.1 - 4e-06 27.0 9.5 7.5e-06 26.1 9.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP83554.1 - 2.5e-05 24.2 3.5 2.5e-05 24.2 3.5 2.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP83554.1 - 0.00021 21.2 12.2 0.00046 20.1 12.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 PRP83554.1 - 0.02 14.6 6.3 0.064 13.0 6.3 1.9 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 PRP83554.1 - 0.022 14.6 10.3 0.046 13.6 10.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PRP83554.1 - 0.039 13.8 5.1 0.077 12.9 5.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 PRP83554.1 - 0.079 13.0 9.7 0.35 11.0 9.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PRP83554.1 - 0.28 11.4 8.7 1.2 9.4 8.8 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CarboxypepD_reg PF13620.6 PRP83555.1 - 2e-11 44.0 0.5 7.2e-11 42.2 0.2 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PRP83555.1 - 7.4e-07 29.1 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain SdrD_B PF17210.3 PRP83555.1 - 0.0024 18.1 0.1 0.0044 17.2 0.1 1.4 1 0 0 1 1 1 1 SdrD B-like domain ATG27 PF09451.10 PRP83555.1 - 0.0058 16.5 0.1 0.0095 15.8 0.1 1.3 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 PRP83555.1 - 0.0066 16.5 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat bMG3 PF11974.8 PRP83555.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain DUF220 PF02713.14 PRP83555.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF220 L_lactis_ph-MCP PF06673.11 PRP83555.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein EMP24_GP25L PF01105.24 PRP83555.1 - 0.21 11.5 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Y_phosphatase PF00102.27 PRP83556.1 - 4.5e-65 219.5 0.0 7.2e-65 218.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ank_2 PF12796.7 PRP83556.1 - 1.3e-22 80.1 0.1 4.3e-08 33.6 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP83556.1 - 3.1e-19 69.1 0.2 2.4e-09 37.5 0.1 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP83556.1 - 1.7e-14 52.5 0.7 0.0042 17.5 0.0 6.6 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 PRP83556.1 - 2.2e-14 53.2 1.7 0.0021 18.4 0.1 6.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 PRP83556.1 - 3.1e-12 46.5 2.3 9.6e-08 32.2 0.2 4.5 2 2 3 5 5 5 2 Ankyrin repeats (many copies) CUE PF02845.16 PRP83556.1 - 8e-06 25.4 1.5 1.5e-05 24.5 0.1 2.2 3 0 0 3 3 3 1 CUE domain DSPc PF00782.20 PRP83556.1 - 0.00019 21.2 0.0 0.00065 19.5 0.0 1.9 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SH2 PF00017.24 PRP83556.1 - 0.0037 17.3 0.0 0.0093 16.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Y_phosphatase3 PF13350.6 PRP83556.1 - 0.011 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family HBS1_N PF08938.10 PRP83556.1 - 0.044 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 HBS1 N-terminus SH2_2 PF14633.6 PRP83556.1 - 0.1 12.0 0.2 0.5 9.7 0.0 2.2 2 1 0 2 2 2 0 SH2 domain PP2C PF00481.21 PRP83558.1 - 5.2e-51 173.7 0.0 8.1e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PRP83558.1 - 0.0019 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP83558.1 - 0.059 13.3 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Ras PF00071.22 PRP83559.1 - 8.3e-53 178.3 1.3 1.4e-52 177.6 0.6 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP83559.1 - 6e-26 91.0 0.3 2.2e-25 89.2 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP83559.1 - 2.7e-10 40.0 0.1 4.4e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP83559.1 - 3.9e-06 26.9 0.4 0.019 14.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP83559.1 - 0.00028 21.0 0.2 0.00084 19.4 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP83559.1 - 0.00029 20.5 0.4 0.00088 18.9 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PRP83559.1 - 0.0019 18.5 0.9 0.015 15.6 0.2 2.6 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.10 PRP83559.1 - 0.0024 17.3 0.4 0.0068 15.9 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 PRP83559.1 - 0.0036 17.1 0.4 0.51 10.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 PRP83559.1 - 0.004 16.7 0.4 2.7 7.5 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_7 PF12775.7 PRP83559.1 - 0.012 15.1 0.2 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 PRP83559.1 - 0.013 14.9 0.3 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 PRP83559.1 - 0.017 15.5 0.1 0.034 14.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF4504 PF14953.6 PRP83559.1 - 0.02 14.3 0.2 0.029 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) ABC_tran PF00005.27 PRP83559.1 - 0.03 14.8 0.7 0.089 13.3 0.7 2.1 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 PRP83559.1 - 0.033 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 PRP83559.1 - 0.04 13.9 0.1 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 PRP83559.1 - 0.041 12.7 0.0 0.089 11.6 0.0 1.5 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_29 PF13555.6 PRP83559.1 - 0.096 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lipase_3 PF01764.25 PRP83560.1 - 1.9e-21 76.4 0.0 3.7e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) fn3 PF00041.21 PRP83560.1 - 1.6e-11 44.4 2.6 3.2e-11 43.4 0.9 2.5 2 1 1 3 3 3 1 Fibronectin type III domain Hydrolase_4 PF12146.8 PRP83560.1 - 0.21 10.8 0.0 0.71 9.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 PRP83560.1 - 0.22 11.6 0.1 0.35 10.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Sen15 PF09631.10 PRP83561.1 - 1.6e-22 79.7 0.7 1.9e-22 79.5 0.3 1.3 2 0 0 2 2 2 1 Sen15 protein dUTPase PF00692.19 PRP83561.1 - 0.086 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 dUTPase WD40 PF00400.32 PRP83562.1 - 9e-53 175.1 22.2 2.5e-08 34.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP83562.1 - 1.8e-11 44.2 0.6 0.037 14.3 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP83562.1 - 9.2e-05 21.3 4.9 0.34 9.5 0.0 5.0 2 2 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 PRP83562.1 - 0.00012 22.1 0.2 0.0036 17.2 0.0 2.8 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 PRP83562.1 - 0.00021 19.9 0.2 0.066 11.7 0.1 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 PRP83562.1 - 0.0011 18.1 0.6 3.1 6.7 0.0 4.0 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PRP83562.1 - 0.0016 18.3 1.7 6.2 6.9 0.1 4.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 PRP83562.1 - 0.002 17.5 0.0 0.34 10.2 0.0 2.4 2 0 0 2 2 2 2 WD40-like domain Sulfate_transp PF00916.20 PRP83563.1 - 1.2e-20 73.7 26.0 1.8e-20 73.0 26.0 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PRP83563.1 - 5.8e-13 48.5 0.1 2e-12 46.8 0.1 1.9 1 1 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 PRP83563.1 - 7.6e-10 38.7 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2417 PF10329.9 PRP83563.1 - 0.0032 16.9 0.5 0.0087 15.5 0.5 1.7 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF5362 PF17319.2 PRP83563.1 - 0.39 10.6 6.0 0.58 10.0 1.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5362) NHase_beta PF02211.15 PRP83564.1 - 0.024 14.7 0.4 0.039 14.0 0.1 1.4 2 0 0 2 2 2 0 Nitrile hydratase beta subunit SelK_SelG PF10961.8 PRP83564.1 - 0.13 12.9 0.1 0.5 11.0 0.1 2.0 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Cupin_8 PF13621.6 PRP83565.1 - 3.4e-21 76.1 0.3 6.9e-20 71.8 0.3 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PRP83565.1 - 2.3e-18 66.7 0.3 6.8e-18 65.2 0.3 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Topoisom_bac PF01131.20 PRP83566.1 - 1e-111 373.9 0.0 1.4e-111 373.5 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase zf-CCHC PF00098.23 PRP83566.1 - 5.6e-23 79.9 40.4 6.4e-07 29.2 4.5 4.9 4 0 0 4 4 4 4 Zinc knuckle Toprim PF01751.22 PRP83566.1 - 5.2e-13 49.1 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.12 PRP83566.1 - 8.1e-12 45.0 4.1 8.1e-12 45.0 4.1 3.4 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.19 PRP83566.1 - 1.1e-11 44.2 0.5 1.1e-11 44.2 0.5 4.4 5 0 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger zf-CCHC_2 PF13696.6 PRP83566.1 - 6e-07 29.2 43.3 0.0015 18.3 1.4 5.9 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.6 PRP83566.1 - 3.7e-05 23.6 18.4 0.14 12.1 0.2 4.9 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 PRP83566.1 - 0.031 14.0 23.0 0.2 11.4 1.3 4.9 4 0 0 4 4 4 0 Zinc knuckle eIF3g PF12353.8 PRP83566.1 - 0.69 10.3 20.6 1.6 9.1 0.5 4.7 4 0 0 4 4 4 0 Eukaryotic translation initiation factor 3 subunit G HSBP1 PF06825.12 PRP83567.1 - 4.9e-18 64.7 4.1 6.1e-18 64.4 4.1 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Caprin-1_C PF12287.8 PRP83567.1 - 0.025 14.7 0.8 0.025 14.7 0.8 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term NPV_P10 PF05531.12 PRP83567.1 - 0.037 14.5 0.6 0.072 13.6 0.6 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein RCC1 PF00415.18 PRP83568.1 - 2.9e-19 69.4 0.8 0.008 16.8 0.0 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP83568.1 - 2.6e-11 43.0 7.0 4.7e-05 23.1 0.0 6.1 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat Na_H_Exchanger PF00999.21 PRP83568.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family U-box PF04564.15 PRP83569.1 - 3e-16 59.4 0.0 7.5e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 PRP83569.1 - 0.001 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 PRP83569.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 PRP83569.1 - 0.0081 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Phage_ABA_S PF18066.1 PRP83569.1 - 0.046 14.4 0.2 0.082 13.6 0.2 1.5 1 0 0 1 1 1 0 Phage ABA sandwich domain Sugarporin_N PF11471.8 PRP83569.1 - 0.055 13.4 0.4 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF2382 PF09557.10 PRP83569.1 - 0.08 13.2 9.3 0.17 12.2 9.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) Atg14 PF10186.9 PRP83569.1 - 0.12 11.4 7.3 0.16 11.1 7.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 PRP83569.1 - 1.7 8.7 4.2 2.8 8.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-I PF07778.11 PRP83569.1 - 2 7.0 5.6 3.1 6.4 5.6 1.2 1 0 0 1 1 1 0 Mis6 DUF16 PF01519.16 PRP83569.1 - 2.4 8.7 8.7 0.31 11.6 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 PRP83569.1 - 3.6 8.2 10.7 3.7 8.2 7.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4821 PF16092.5 PRP83570.1 - 4.8e-31 108.4 1.1 7.2e-28 97.9 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 PRP83570.1 - 1.3e-10 41.0 0.1 9.6e-09 34.9 0.1 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP83570.1 - 0.0011 19.4 0.5 0.47 11.0 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP83570.1 - 0.023 14.3 0.0 0.058 13.0 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Acetyltransf_1 PF00583.25 PRP83570.1 - 0.1 12.8 0.0 7.5 6.8 0.0 2.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family TrkA_N PF02254.18 PRP83570.1 - 0.2 11.9 0.5 0.75 10.1 0.5 2.0 1 0 0 1 1 1 0 TrkA-N domain PhoLip_ATPase_C PF16212.5 PRP83571.1 - 1e-65 221.9 18.7 1e-65 221.9 18.7 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP83571.1 - 2.1e-22 78.6 6.5 2.1e-22 78.6 6.5 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PRP83571.1 - 1.1e-10 42.2 0.1 2.1e-05 24.9 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PRP83571.1 - 1e-06 28.4 1.6 4.1e-06 26.4 0.0 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 PRP83571.1 - 1.6e-05 24.9 0.0 5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP83571.1 - 0.0026 17.6 0.1 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_1_2 PF13603.6 PRP83571.1 - 0.15 11.5 0.0 0.73 9.3 0.0 2.1 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 Response_reg PF00072.24 PRP83572.1 - 6.5e-22 77.8 0.2 1.3e-21 76.9 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain LRR_8 PF13855.6 PRP83572.1 - 4.5e-12 45.5 14.5 2.7e-07 30.2 5.5 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 PRP83572.1 - 2.1e-09 36.7 21.2 0.01 15.8 0.2 7.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 PRP83572.1 - 5.9e-09 36.1 21.1 2.6e-05 24.5 2.7 5.6 2 2 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP83572.1 - 0.0025 18.1 15.2 16 6.6 0.0 7.3 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_9 PF14580.6 PRP83572.1 - 0.033 13.7 6.7 0.023 14.2 2.4 2.2 1 1 0 2 2 2 0 Leucine-rich repeat Pkinase_Tyr PF07714.17 PRP83573.1 - 1.2e-46 159.1 0.0 2.3e-46 158.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83573.1 - 7.5e-44 150.1 0.0 1.6e-43 149.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 PRP83573.1 - 1e-22 80.2 1.2 0.00059 20.4 0.0 5.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP83573.1 - 1.3e-18 67.3 0.3 5.2e-11 43.0 0.1 3.4 3 1 1 4 4 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP83573.1 - 1.6e-14 53.8 2.0 2.6e-08 34.0 0.3 4.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP83573.1 - 4.3e-14 52.2 0.2 0.0001 22.5 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat C2 PF00168.30 PRP83573.1 - 3.4e-13 49.8 0.0 7.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain SAM_1 PF00536.30 PRP83573.1 - 5.8e-10 39.5 0.3 1.4e-09 38.2 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 PRP83573.1 - 3.8e-09 36.1 0.3 0.0079 16.6 0.0 5.9 6 0 0 6 6 6 1 Ankyrin repeat SAM_2 PF07647.17 PRP83573.1 - 2.7e-08 33.8 0.3 5.7e-08 32.8 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.23 PRP83573.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 PRP83573.1 - 0.095 12.9 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 ABC1 family Seadorna_VP7 PF07387.11 PRP83573.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MnmE_helical PF12631.7 PRP83573.1 - 0.14 12.3 3.3 0.39 10.9 3.3 1.8 1 1 0 1 1 1 0 MnmE helical domain Haspin_kinase PF12330.8 PRP83573.1 - 1.2 8.0 11.2 1.2 8.1 0.0 3.9 4 0 0 4 4 4 0 Haspin like kinase domain SART-1 PF03343.13 PRP83573.1 - 4.4 5.7 13.1 0.082 11.4 6.3 1.5 2 0 0 2 2 2 0 SART-1 family HA PF03457.14 PRP83574.1 - 1.5e-17 63.7 2.6 1.4e-08 34.9 0.0 3.3 3 0 0 3 3 3 3 Helicase associated domain PAXX PF15384.6 PRP83574.1 - 0.2 11.3 6.1 0.12 12.1 1.3 2.4 2 1 1 3 3 3 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DUF755 PF05501.11 PRP83574.1 - 9.6 6.5 13.7 8.6 6.7 6.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF755) PKD_channel PF08016.12 PRP83576.1 - 1.4e-12 47.0 4.8 1.4e-12 47.0 4.8 1.6 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 PRP83576.1 - 6.5e-10 38.7 16.1 1.2e-09 37.8 16.1 1.4 1 0 0 1 1 1 1 Ion transport protein DUF2973 PF11189.8 PRP83576.1 - 0.0016 18.5 1.5 1.5 9.0 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF2973) DUF4521 PF15021.6 PRP83576.1 - 0.42 10.5 4.8 0.69 9.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4521) PEX11 PF05648.14 PRP83577.1 - 2.7e-55 187.2 3.4 3.2e-55 187.0 3.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PUB_1 PF18486.1 PRP83577.1 - 0.03 14.2 0.2 0.066 13.1 0.2 1.5 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain DUF4639 PF15479.6 PRP83578.1 - 3e-12 46.3 3.3 6.3e-12 45.3 2.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4639) CSD PF00313.22 PRP83579.1 - 3e-05 23.8 0.2 8.2e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain Vac_Fusion PF02346.16 PRP83579.1 - 0.069 12.8 0.5 15 5.3 0.1 3.0 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 UPF0242 PF06785.11 PRP83579.1 - 0.18 11.9 13.9 0.76 9.8 13.9 2.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 PRP83579.1 - 1.2 8.5 5.9 2.5 7.4 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 PRP83579.1 - 4.9 7.8 11.0 12 6.6 9.8 2.4 1 1 0 1 1 1 0 Initiation control protein YabA ALMT PF11744.8 PRP83579.1 - 5.6 5.7 8.7 15 4.3 8.7 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter Histone PF00125.24 PRP83580.1 - 5.8e-33 114.0 2.8 8.2e-33 113.6 2.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PRP83580.1 - 0.00037 20.6 0.1 0.00069 19.7 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PRP83580.1 - 0.0016 18.7 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 PRP83580.1 - 0.0079 16.4 0.3 0.014 15.5 0.3 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TPR_1 PF00515.28 PRP83581.1 - 8.9e-43 142.4 33.6 2.9e-05 23.7 0.1 17.8 19 1 1 20 20 17 7 Tetratricopeptide repeat TPR_2 PF07719.17 PRP83581.1 - 4.9e-41 135.6 34.7 0.00026 20.9 0.0 21.7 24 0 0 24 24 21 6 Tetratricopeptide repeat TPR_14 PF13428.6 PRP83581.1 - 4.2e-37 123.6 24.8 0.017 15.9 1.5 22.6 17 5 7 25 25 24 4 Tetratricopeptide repeat TPR_16 PF13432.6 PRP83581.1 - 1.1e-32 112.4 2.9 9.7e-06 26.1 0.9 15.3 15 2 1 17 17 15 5 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83581.1 - 1.6e-29 102.2 26.7 0.001 19.5 0.6 16.9 16 1 1 18 18 16 4 Tetratricopeptide repeat TPR_8 PF13181.6 PRP83581.1 - 1.8e-27 93.2 51.5 0.0061 16.7 0.0 19.2 21 0 0 21 21 18 8 Tetratricopeptide repeat TPR_11 PF13414.6 PRP83581.1 - 8.3e-26 89.4 38.6 0.17 11.6 0.1 18.2 15 3 3 18 18 18 10 TPR repeat TPR_17 PF13431.6 PRP83581.1 - 2.9e-21 74.3 33.4 0.013 15.9 0.1 18.6 20 0 0 20 20 19 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP83581.1 - 1.8e-18 65.9 28.9 1.8 9.4 0.0 17.4 17 1 0 17 17 15 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP83581.1 - 2.2e-17 63.1 36.6 0.00071 19.8 0.1 14.0 13 3 1 15 15 14 5 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP83581.1 - 3.8e-15 55.9 20.3 0.0083 16.3 0.0 12.3 9 2 2 11 11 11 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PRP83581.1 - 4.5e-12 46.0 3.1 0.17 12.0 0.0 7.5 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 PRP83581.1 - 2.2e-10 40.2 24.9 0.0081 15.4 0.9 9.4 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 PRP83581.1 - 5.4e-09 35.5 29.2 0.15 12.1 0.0 12.8 15 0 0 15 15 11 3 Tetratricopeptide repeat TPR_10 PF13374.6 PRP83581.1 - 1.2e-07 31.3 18.9 1.2 9.1 0.5 11.2 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_20 PF14561.6 PRP83581.1 - 5.9e-06 26.5 16.4 0.056 13.8 0.0 7.8 9 0 0 9 9 6 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PRP83581.1 - 2.7e-05 23.8 3.2 0.53 9.9 0.1 5.6 5 0 0 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TOM20_plant PF06552.12 PRP83581.1 - 0.00022 21.0 9.0 0.64 9.7 0.0 6.3 7 1 0 8 8 7 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_21 PF09976.9 PRP83581.1 - 0.002 17.8 30.4 0.33 10.6 0.0 8.7 9 1 1 10 10 7 2 Tetratricopeptide repeat-like domain Sel1 PF08238.12 PRP83581.1 - 0.0051 17.4 2.2 2.6 8.8 0.1 4.2 3 0 0 3 3 3 1 Sel1 repeat TPR_4 PF07721.14 PRP83581.1 - 0.0059 17.1 11.0 7.3 7.5 0.0 8.3 9 0 0 9 9 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 PRP83581.1 - 0.012 15.6 2.0 35 4.5 0.0 5.9 5 0 0 5 5 5 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 PRP83581.1 - 0.027 14.2 15.8 0.55 9.9 0.1 7.6 8 2 1 9 9 8 0 26S proteasome subunit RPN7 AraC_binding_2 PF14525.6 PRP83581.1 - 0.036 13.8 0.3 9.7 5.8 0.1 2.7 3 0 0 3 3 2 0 AraC-binding-like domain Fis1_TPR_C PF14853.6 PRP83581.1 - 0.073 13.2 4.7 8.7 6.5 0.1 5.6 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 PRP83581.1 - 1.1 9.3 7.4 37 4.5 0.5 5.5 6 1 0 6 6 4 0 Anaphase-promoting complex subunit 5 BTAD PF03704.17 PRP83581.1 - 4.8 7.6 19.6 3.3 8.1 0.1 6.5 8 1 0 8 8 6 0 Bacterial transcriptional activator domain NHase_beta PF02211.15 PRP83582.1 - 0.0098 15.9 0.2 0.018 15.1 0.1 1.4 2 0 0 2 2 2 1 Nitrile hydratase beta subunit SelK_SelG PF10961.8 PRP83582.1 - 0.14 12.8 0.1 0.5 11.0 0.1 2.0 2 0 0 2 2 2 0 Selenoprotein SelK_SelG Endosulfine PF04667.17 PRP83583.1 - 2e-05 24.6 2.4 4.7e-05 23.4 2.4 1.8 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Imm32 PF15566.6 PRP83583.1 - 0.23 11.3 0.0 0.59 10.0 0.0 1.7 2 0 0 2 2 2 0 Immunity protein 32 DUF4395 PF14340.6 PRP83584.1 - 2.1e-08 34.6 0.3 2.1e-08 34.6 0.3 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF4395) Ank_2 PF12796.7 PRP83585.1 - 2.9e-09 37.4 8.4 0.46 11.1 0.2 6.5 4 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP83585.1 - 4.2 8.3 16.2 28 5.7 0.1 8.7 12 1 0 12 12 12 0 Ankyrin repeat ABC_membrane_2 PF06472.15 PRP83586.1 - 2e-96 322.5 5.1 2.6e-96 322.2 5.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PRP83586.1 - 2e-18 67.2 0.0 8e-18 65.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PRP83586.1 - 0.00039 20.3 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbmA_BacA PF05992.12 PRP83586.1 - 0.0028 17.1 0.2 0.0079 15.7 0.2 1.7 1 1 0 1 1 1 1 SbmA/BacA-like family AAA_29 PF13555.6 PRP83586.1 - 0.0054 16.5 0.0 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP83586.1 - 0.0056 17.2 0.1 0.0056 17.2 0.1 2.6 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 PRP83586.1 - 0.0088 16.0 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 PRP83586.1 - 0.03 13.7 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PRP83586.1 - 0.12 12.8 0.1 0.36 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF533 PF04391.12 PRP83586.1 - 0.16 11.5 0.4 0.28 10.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Inhibitor_I78 PF11720.8 PRP83587.1 - 9.9e-07 28.7 0.0 3.2e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I78 family DUF4296 PF14129.6 PRP83588.1 - 0.039 14.5 0.1 13 6.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) CAP_GLY PF01302.25 PRP83591.1 - 1.2e-23 82.8 3.0 1.8e-23 82.3 3.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 PRP83591.1 - 1.9e-20 73.1 0.0 3e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain adh_short PF00106.25 PRP83593.1 - 1.2e-43 148.9 2.7 1.3e-43 148.7 1.8 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP83593.1 - 2.8e-41 141.6 0.4 5.1e-41 140.8 0.4 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP83593.1 - 4.5e-08 33.2 0.2 8.9e-08 32.2 0.2 1.4 1 0 0 1 1 1 1 KR domain EB PF01683.18 PRP83593.1 - 0.0078 16.5 1.5 0.023 15.0 1.5 1.8 1 0 0 1 1 1 1 EB module EGF_2 PF07974.13 PRP83593.1 - 0.015 15.7 8.3 0.035 14.5 8.3 1.7 1 0 0 1 1 1 0 EGF-like domain PLDc PF00614.22 PRP83594.1 - 7.8e-20 70.2 2.6 3.9e-11 42.6 0.4 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 PRP83594.1 - 1.2e-15 57.6 0.1 1e-09 38.4 0.1 2.6 2 0 0 2 2 2 2 PLD-like domain PH PF00169.29 PRP83594.1 - 0.00032 21.2 0.1 0.38 11.3 0.0 3.1 2 1 0 2 2 2 2 PH domain TPR_1 PF00515.28 PRP83595.1 - 8.4e-39 129.8 26.4 6.4e-06 25.8 0.1 11.1 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 PRP83595.1 - 2.1e-38 127.3 31.6 0.00011 22.1 0.1 11.3 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 PRP83595.1 - 2.5e-33 111.5 24.2 0.0011 19.0 0.0 11.4 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 PRP83595.1 - 1.7e-27 95.5 18.5 1.7e-05 25.0 0.2 7.3 6 2 1 7 7 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83595.1 - 1.4e-21 76.7 5.3 0.00013 22.3 0.1 7.3 7 2 1 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 PRP83595.1 - 2.2e-19 68.5 3.6 0.0015 19.1 0.1 10.0 6 4 5 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 PRP83595.1 - 3.4e-16 58.7 14.7 0.22 12.2 0.0 10.4 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP83595.1 - 1.3e-14 54.5 5.4 0.0005 20.7 1.0 5.5 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP83595.1 - 1.6e-13 50.1 20.5 0.017 14.8 0.3 8.6 6 1 2 8 8 8 5 TPR repeat TPR_7 PF13176.6 PRP83595.1 - 5.4e-13 48.0 11.1 0.019 15.0 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP83595.1 - 8.3e-12 44.6 31.3 0.0017 18.6 0.0 9.8 9 2 0 9 9 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 PRP83595.1 - 3.9e-09 36.1 14.1 0.032 14.1 0.7 8.2 8 0 0 8 8 8 3 Tetratricopeptide repeat F-box PF00646.33 PRP83595.1 - 2.3e-08 33.7 3.0 2.7e-08 33.5 1.2 2.0 2 0 0 2 2 2 1 F-box domain ANAPC3 PF12895.7 PRP83595.1 - 3.1e-08 33.7 24.6 0.0008 19.6 1.0 5.5 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PRP83595.1 - 6.2e-08 32.7 0.1 0.28 11.3 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 PRP83595.1 - 0.00014 22.2 0.0 11 7.0 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat SNAP PF14938.6 PRP83595.1 - 0.003 17.0 0.6 0.003 17.0 0.6 3.8 3 2 1 4 4 4 1 Soluble NSF attachment protein, SNAP HemY_N PF07219.13 PRP83595.1 - 0.0032 17.7 0.9 2.4 8.4 0.1 3.8 3 1 1 4 4 4 1 HemY protein N-terminus F-box-like PF12937.7 PRP83595.1 - 0.0039 17.0 0.5 0.018 14.9 0.5 2.1 2 0 0 2 2 2 1 F-box-like TPR_15 PF13429.6 PRP83595.1 - 0.0064 15.7 8.7 1.7 7.7 0.3 4.5 3 1 2 5 5 5 1 Tetratricopeptide repeat Sel1 PF08238.12 PRP83595.1 - 0.029 15.1 9.9 6.4 7.6 0.0 6.8 7 0 0 7 7 7 0 Sel1 repeat TPR_21 PF09976.9 PRP83595.1 - 0.049 13.3 4.0 0.24 11.1 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 PRP83595.1 - 0.05 13.3 20.1 0.15 11.7 0.3 5.0 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) SRP_TPR_like PF17004.5 PRP83595.1 - 0.089 12.8 15.3 0.14 12.2 0.5 3.8 4 0 0 4 4 4 0 Putative TPR-like repeat RPN7 PF10602.9 PRP83595.1 - 0.28 10.9 11.0 1.8 8.2 0.1 4.0 3 1 0 3 3 3 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 PRP83595.1 - 0.51 10.5 28.0 1.9 8.6 0.4 7.5 7 1 1 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat Syntaxin-6_N PF09177.11 PRP83595.1 - 1.6 9.4 5.3 5.6 7.6 1.9 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal zf-C4H2 PF10146.9 PRP83595.1 - 5.1 7.3 9.9 2.8 8.2 0.9 2.6 2 0 0 2 2 2 0 Zinc finger-containing protein TfuA PF07812.12 PRP83596.1 - 0.079 12.7 0.0 0.079 12.7 0.0 1.0 1 0 0 1 1 1 0 TfuA-like protein DEAD PF00270.29 PRP83597.1 - 5.6e-44 150.0 0.0 1.2e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP83597.1 - 1.8e-26 92.7 0.5 6.9e-26 90.8 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PRP83597.1 - 7.5e-22 77.3 0.1 3.4e-15 56.0 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4217) ResIII PF04851.15 PRP83597.1 - 1.8e-08 34.6 0.0 1.8e-08 34.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PRP83597.1 - 0.018 14.4 0.0 0.018 14.4 0.0 3.0 3 1 1 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 PRP83597.1 - 0.097 12.9 0.1 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain SurA_N_2 PF13623.6 PRP83598.1 - 0.046 13.6 1.7 0.062 13.2 1.7 1.1 1 0 0 1 1 1 0 SurA N-terminal domain SurA_N_3 PF13624.6 PRP83598.1 - 0.068 13.0 2.6 0.082 12.7 2.6 1.1 1 0 0 1 1 1 0 SurA N-terminal domain Ribonuclease_3 PF00636.26 PRP83599.1 - 7.1e-37 126.2 1.5 6.7e-20 71.7 0.0 3.8 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 PRP83599.1 - 3.1e-34 117.9 0.2 3.7e-19 69.2 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease-III-like PAZ PF02170.22 PRP83599.1 - 2e-14 53.5 0.2 4.1e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 PAZ domain DUF2500 PF10694.9 PRP83599.1 - 0.092 13.3 0.0 0.54 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) FAD_binding_1 PF00667.20 PRP83600.1 - 0.0083 15.7 0.3 0.029 14.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain BRD4_CDT PF17105.5 PRP83600.1 - 2.7 7.7 9.5 1.3 8.7 1.9 2.8 2 1 0 2 2 2 0 C-terminal domain of bromodomain protein 4 LRR_6 PF13516.6 PRP83601.1 - 1.4e-08 34.1 20.4 0.078 13.1 0.3 9.2 11 0 0 11 11 11 3 Leucine Rich repeat LRR_4 PF12799.7 PRP83601.1 - 0.00017 21.9 6.7 0.0016 18.8 0.3 6.1 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP83601.1 - 0.0018 18.0 2.9 0.012 15.3 0.7 3.6 3 1 0 3 3 3 1 Leucine rich repeat Sec7_N PF12783.7 PRP83601.1 - 0.021 14.7 4.8 0.57 10.1 0.5 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal LRR_1 PF00560.33 PRP83601.1 - 0.36 11.5 11.3 30 5.7 0.0 7.0 8 1 0 8 8 8 0 Leucine Rich Repeat DUF2512 PF10710.9 PRP83601.1 - 7.3 6.3 8.2 12 5.5 6.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2512) DoxX_3 PF13781.6 PRP83602.1 - 0.029 15.0 1.8 0.15 12.7 1.1 2.0 2 0 0 2 2 2 0 DoxX-like family PatG_D PF18047.1 PRP83603.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 PatG Domain DUF21 PF01595.20 PRP83604.1 - 1.9e-36 125.4 0.1 2.8e-36 124.9 0.1 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PRP83604.1 - 4.9e-09 36.5 0.7 0.0022 18.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain Mersacidin PF16934.5 PRP83604.1 - 0.15 11.8 0.0 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) HSP20 PF00011.21 PRP83605.1 - 1.4e-18 66.9 0.5 3.8e-18 65.5 0.3 1.8 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP83605.1 - 7.1e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA NHL PF01436.21 PRP83606.1 - 5.2e-26 89.3 1.2 0.0003 20.7 0.1 7.8 7 0 0 7 7 7 6 NHL repeat AhpC-TSA PF00578.21 PRP83606.1 - 3.7e-09 36.6 0.0 7.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 PRP83606.1 - 3.4e-07 30.5 0.0 7.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like SGL PF08450.12 PRP83606.1 - 1.9e-06 27.7 1.3 0.00017 21.3 0.3 4.0 2 2 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 PRP83606.1 - 3.1e-05 24.1 0.0 5.9 7.2 0.0 4.8 4 1 1 5 5 5 2 Arylesterase Redoxin PF08534.10 PRP83606.1 - 6.3e-05 22.7 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.20 PRP83606.1 - 0.0034 17.4 0.0 2.1 8.4 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin Lactonase PF10282.9 PRP83606.1 - 0.091 12.0 0.0 8.9 5.5 0.0 3.6 3 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Thioredoxin_2 PF13098.6 PRP83606.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain CAP PF00188.26 PRP83607.1 - 4.3e-24 85.7 7.3 4.3e-24 85.7 7.3 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family HemN_C PF06969.16 PRP83609.1 - 2.7e-11 43.3 0.8 6.4e-11 42.2 0.8 1.7 1 0 0 1 1 1 1 HemN C-terminal domain Radical_SAM PF04055.21 PRP83609.1 - 7e-06 26.5 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily HTH_45 PF14947.6 PRP83609.1 - 0.095 12.7 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix ANAPC4_WD40 PF12894.7 PRP83610.1 - 0.00036 20.8 2.1 2.7 8.4 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP83610.1 - 0.093 13.6 0.8 78 4.4 0.0 4.1 4 1 0 4 4 4 0 WD domain, G-beta repeat Radial_spoke PF04712.12 PRP83611.1 - 2.3e-143 478.7 4.3 2.3e-143 478.7 4.3 1.6 1 1 1 2 2 2 1 Radial spokehead-like protein GRASP55_65 PF04495.14 PRP83612.1 - 5.1e-63 211.5 0.0 4.2e-44 150.2 0.0 2.4 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 PRP83612.1 - 1.8e-07 31.4 0.0 0.025 14.9 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 PRP83612.1 - 6e-07 29.2 0.0 0.02 14.7 0.0 2.8 2 1 0 2 2 2 2 PDZ domain DPBB_1 PF03330.18 PRP83612.1 - 0.0001 22.5 0.1 0.00041 20.6 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Tricorn_PDZ PF14685.6 PRP83612.1 - 0.011 15.7 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain PhzC-PhzF PF02567.16 PRP83613.1 - 8.2e-31 107.5 0.0 1.2e-15 57.7 0.0 2.4 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein DUF4614 PF15391.6 PRP83613.1 - 1.3e-10 41.6 0.1 1.3e-10 41.6 0.1 9.0 7 2 3 10 10 10 1 Domain of unknown function (DUF4614) Glyco_hydro_72 PF03198.14 PRP83614.1 - 6.1e-107 357.5 1.2 9.1e-107 356.9 1.2 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 PRP83614.1 - 1.3e-14 54.6 2.1 2.9e-14 53.5 2.1 1.6 1 0 0 1 1 1 1 X8 domain TFIIF_alpha PF05793.12 PRP83614.1 - 2.6e-13 49.4 47.7 1.9e-10 40.0 44.8 3.2 2 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1475 PF07343.11 PRP83615.1 - 3.9e-16 59.6 0.4 5.2e-16 59.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1475) DUF2156 PF09924.9 PRP83617.1 - 5.5e-23 81.4 0.0 7.7e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) CUE PF02845.16 PRP83618.1 - 5.4e-10 38.8 0.3 5.9e-09 35.5 0.1 2.2 2 0 0 2 2 2 1 CUE domain zf-RING_2 PF13639.6 PRP83618.1 - 4.8e-05 23.6 13.8 0.02 15.2 5.4 2.4 1 1 1 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 PRP83618.1 - 0.0013 18.6 11.5 0.18 11.7 1.5 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP83618.1 - 0.011 15.6 6.4 0.71 9.8 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP83618.1 - 0.013 15.2 2.2 0.036 13.8 2.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger TMEM171 PF15471.6 PRP83618.1 - 0.05 12.6 0.5 0.089 11.8 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-C3HC4 PF00097.25 PRP83618.1 - 0.054 13.4 8.7 0.63 10.0 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP83618.1 - 0.28 11.5 15.5 9.8 6.6 15.7 2.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP83618.1 - 0.34 11.0 4.4 0.41 10.7 0.8 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 PRP83618.1 - 5.3 7.1 7.1 35 4.4 7.1 2.2 1 1 0 1 1 1 0 zinc-RING finger domain TIP49 PF06068.13 PRP83619.1 - 4.6e-168 558.9 0.3 5.9e-168 558.5 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 PRP83619.1 - 1.2e-24 86.2 0.0 8.3e-24 83.5 0.1 2.4 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 PRP83619.1 - 1.3e-11 45.1 1.5 1.1e-06 29.1 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PRP83619.1 - 1.8e-09 37.6 0.3 6.1e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PRP83619.1 - 7.6e-07 29.5 0.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PRP83619.1 - 8.8e-05 22.5 0.1 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP83619.1 - 9.3e-05 22.9 0.0 0.0018 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 PRP83619.1 - 0.00017 21.9 0.1 0.0019 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PRP83619.1 - 0.00023 20.6 0.2 0.014 14.8 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 PRP83619.1 - 0.00023 21.5 1.8 0.66 10.3 0.2 3.0 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 PRP83619.1 - 0.0022 17.7 0.1 1 9.0 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 PRP83619.1 - 0.0029 18.1 0.2 0.013 16.0 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 PRP83619.1 - 0.0046 16.5 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PRP83619.1 - 0.0047 16.2 0.2 0.012 14.8 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 PRP83619.1 - 0.0093 16.1 0.0 0.037 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 PRP83619.1 - 0.015 14.7 0.1 0.039 13.3 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATPase PF06745.13 PRP83619.1 - 0.016 14.6 1.0 0.18 11.1 0.1 2.3 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 PRP83619.1 - 0.017 15.1 0.1 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 PRP83619.1 - 0.022 14.8 0.1 2.6 8.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 PRP83619.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 PRP83619.1 - 0.051 13.6 0.1 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 PRP83619.1 - 0.077 12.5 0.2 0.32 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 PRP83619.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF1827 PF08860.10 PRP83619.1 - 0.41 10.9 3.3 11 6.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1827) Arf PF00025.21 PRP83620.1 - 3e-49 166.8 0.0 6e-49 165.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LON_substr_bdg PF02190.16 PRP83620.1 - 3.7e-26 92.3 0.0 8e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain RPAP1_C PF08620.10 PRP83620.1 - 1.5e-24 85.8 0.0 2.9e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal TPR_1 PF00515.28 PRP83620.1 - 3.9e-18 64.4 17.1 0.00011 21.8 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 PRP83620.1 - 6.9e-18 63.3 15.6 0.00012 21.9 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 PRP83620.1 - 9.6e-11 41.3 43.8 6.9e-10 38.6 10.5 3.7 4 0 0 4 4 3 2 Zinc finger, C3HC4 type (RING finger) Roc PF08477.13 PRP83620.1 - 2.1e-09 37.7 0.1 5.4e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP83620.1 - 5.3e-09 35.9 0.1 5.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Ras family TPR_17 PF13431.6 PRP83620.1 - 6.2e-09 35.6 7.0 0.013 15.8 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 PRP83620.1 - 1.6e-08 34.4 36.9 2.9e-05 24.0 8.8 4.0 3 1 1 4 4 4 2 RING-type zinc-finger SRPRB PF09439.10 PRP83620.1 - 3.6e-08 33.1 0.0 1.3e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit zf-C3HC4_3 PF13920.6 PRP83620.1 - 3.7e-08 33.1 5.7 3.7e-08 33.1 5.7 4.0 4 1 1 5 5 3 2 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 PRP83620.1 - 1.7e-07 31.4 15.5 0.00035 20.8 0.8 5.2 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP83620.1 - 1.8e-07 30.8 14.1 0.19 12.0 0.1 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat G-alpha PF00503.20 PRP83620.1 - 3.4e-07 29.7 0.4 0.0006 19.1 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit zf-RING_2 PF13639.6 PRP83620.1 - 3e-06 27.4 40.0 7.7e-06 26.2 9.9 3.3 3 0 0 3 3 2 2 Ring finger domain TPR_11 PF13414.6 PRP83620.1 - 6e-06 25.8 13.7 0.16 11.7 0.1 4.5 2 1 2 4 4 4 2 TPR repeat zf-C3HC4 PF00097.25 PRP83620.1 - 6.7e-06 25.9 33.7 8.4e-05 22.4 8.8 4.2 5 0 0 5 5 4 2 Zinc finger, C3HC4 type (RING finger) NARP1 PF12569.8 PRP83620.1 - 1.2e-05 24.5 0.3 0.00013 21.0 0.0 2.3 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 zf-C3HC4_4 PF15227.6 PRP83620.1 - 1.2e-05 25.4 8.9 1.2e-05 25.4 8.9 3.8 4 0 0 4 4 3 2 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 PRP83620.1 - 2.2e-05 24.5 7.6 2.2e-05 24.5 7.6 3.4 4 0 0 4 4 2 2 zinc RING finger of MSL2 zf-RING_5 PF14634.6 PRP83620.1 - 2.6e-05 24.1 32.5 0.00034 20.5 8.7 4.0 4 0 0 4 4 3 2 zinc-RING finger domain TPR_16 PF13432.6 PRP83620.1 - 2.8e-05 24.7 8.5 0.019 15.6 0.0 3.6 2 2 1 3 3 3 1 Tetratricopeptide repeat zf-RING_6 PF14835.6 PRP83620.1 - 6.6e-05 22.7 20.6 0.0018 18.1 3.7 2.6 2 0 0 2 2 2 2 zf-RING of BARD1-type protein TPR_14 PF13428.6 PRP83620.1 - 7.5e-05 23.2 3.9 4.9 8.2 0.1 5.5 2 2 4 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83620.1 - 0.00019 21.9 5.8 0.027 15.0 0.0 3.3 2 2 1 3 3 3 1 Tetratricopeptide repeat MMR_HSR1 PF01926.23 PRP83620.1 - 0.0002 21.4 0.0 0.00049 20.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TPR_9 PF13371.6 PRP83620.1 - 0.00025 21.1 1.2 0.23 11.7 1.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat Prok-RING_4 PF14447.6 PRP83620.1 - 0.00054 19.8 8.4 0.00054 19.8 8.4 3.2 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 PRP83620.1 - 0.00085 19.4 0.1 0.47 10.7 0.0 3.0 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.7 PRP83620.1 - 0.0013 19.0 3.9 0.0013 19.0 3.9 3.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain TPR_7 PF13176.6 PRP83620.1 - 0.0057 16.6 7.1 1.8 8.8 0.1 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP83620.1 - 0.0073 16.4 0.6 27 4.9 0.0 3.6 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat zf-RING_4 PF14570.6 PRP83620.1 - 0.01 15.6 25.6 0.076 12.8 5.7 3.4 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain TPR_10 PF13374.6 PRP83620.1 - 0.035 14.0 7.4 40 4.3 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 PRP83620.1 - 0.063 13.3 0.2 0.063 13.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 PRP83620.1 - 0.13 12.3 10.9 2.1 8.5 0.5 3.9 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 PRP83620.1 - 0.98 9.1 5.4 1.2 8.9 1.8 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Glyco_hydro_46 PF01374.18 PRP83621.1 - 2.5e-28 99.1 0.1 3.7e-28 98.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 PAN_4 PF14295.6 PRP83621.1 - 2.7e-07 30.4 5.5 2.7e-07 30.4 5.5 3.4 4 0 0 4 4 4 1 PAN domain Chitin_bind_1 PF00187.19 PRP83621.1 - 6.7e-07 29.7 21.6 6.7e-07 29.7 21.6 3.6 3 1 1 4 4 4 1 Chitin recognition protein PAN_1 PF00024.26 PRP83621.1 - 4.7e-05 23.3 2.8 4.7e-05 23.3 2.8 2.4 2 0 0 2 2 2 1 PAN domain PDH_E1_M PF17831.1 PRP83622.1 - 0.081 12.4 0.0 0.093 12.2 0.0 1.0 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain UDG PF03167.19 PRP83623.1 - 6e-21 75.1 0.0 1.1e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily HSP20 PF00011.21 PRP83624.1 - 1.3e-19 70.2 0.3 1.6e-19 69.9 0.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP83624.1 - 6.5e-07 28.8 0.0 9.4e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DnaJ PF00226.31 PRP83624.1 - 0.0095 16.1 0.2 0.19 11.9 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain BDV_M PF16520.5 PRP83624.1 - 0.16 12.4 0.0 0.25 11.7 0.0 1.3 1 1 0 1 1 1 0 ssRNA-binding matrix protein of Bornaviridae DnaJ_C PF01556.18 PRP83625.1 - 1.6e-27 96.4 0.1 3.5e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ C terminal domain Zw10 PF06248.13 PRP83625.1 - 3.7e-14 52.2 11.2 6.1e-07 28.4 1.3 3.2 1 1 1 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 PRP83625.1 - 8.5e-06 25.6 0.3 8.5e-06 25.6 0.3 1.9 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal WXG100 PF06013.12 PRP83625.1 - 0.095 12.9 3.2 0.78 10.0 0.0 3.4 4 0 0 4 4 4 0 Proteins of 100 residues with WXG COMM_domain PF07258.14 PRP83625.1 - 0.16 12.1 1.1 8.7 6.6 0.0 3.5 3 0 0 3 3 3 0 COMM domain DUF1664 PF07889.12 PRP83625.1 - 2.5 8.1 5.9 12 6.0 0.1 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) PAP_assoc PF03828.19 PRP83626.1 - 5.5e-22 77.7 0.0 1.8e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase PAP_central PF04928.17 PRP83626.1 - 9.5e-06 24.8 0.0 0.013 14.5 0.0 3.4 2 1 0 2 2 2 2 Poly(A) polymerase central domain Polbeta PF18765.1 PRP83626.1 - 0.0057 16.7 0.1 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 PRP83626.1 - 0.015 15.5 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 Nucleotidyltransferase domain Synaptobrevin PF00957.21 PRP83627.1 - 7e-16 57.8 0.7 2e-15 56.4 0.4 1.9 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 PRP83627.1 - 0.00047 20.1 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Mt_ATP-synt_B PF05405.14 PRP83627.1 - 0.02 14.5 0.2 0.039 13.6 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) MIP PF00230.20 PRP83630.1 - 1.6e-46 158.9 6.1 2.1e-46 158.5 6.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF2684 PF10885.8 PRP83630.1 - 0.033 14.3 0.2 0.069 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) DUF389 PF04087.14 PRP83630.1 - 1.5 8.9 8.8 6.2 6.8 1.7 3.7 2 2 0 2 2 2 0 Domain of unknown function (DUF389) Ank_5 PF13857.6 PRP83631.1 - 3.5e-10 39.9 0.1 4.5e-09 36.4 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP83631.1 - 3.1e-09 37.2 0.2 0.00012 22.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP83631.1 - 1.9e-08 34.8 0.2 9.4e-08 32.5 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP83631.1 - 4.1e-08 32.9 0.6 0.0001 22.4 0.3 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 PRP83631.1 - 0.00023 21.5 1.5 0.067 13.7 0.1 3.6 3 1 0 3 3 3 1 Ankyrin repeat E3_binding PF02817.17 PRP83631.1 - 0.074 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 e3 binding domain IF-2B PF01008.17 PRP83632.1 - 4.5e-68 229.5 0.1 5.2e-68 229.3 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 PRP83632.1 - 0.00074 19.5 0.1 0.43 10.5 0.0 2.5 2 0 0 2 2 2 2 DeoR C terminal sensor domain GH101_N PF17995.1 PRP83632.1 - 0.0044 16.7 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 Endo-alpha-N-acetylgalactosaminidase N-terminal Pyridox_ox_2 PF12900.7 PRP83632.1 - 0.064 13.2 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Peptidase_A22B PF04258.13 PRP83635.1 - 1.5e-50 172.4 13.1 7.2e-49 166.8 13.1 2.3 1 1 0 1 1 1 1 Signal peptide peptidase Peptidase_M1 PF01433.20 PRP83636.1 - 6.9e-79 264.4 0.1 1.1e-78 263.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 PRP83636.1 - 1.8e-76 257.7 0.0 2.8e-76 257.1 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PRP83636.1 - 4.6e-42 144.3 0.0 3.9e-41 141.3 0.0 2.5 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain C2 PF00168.30 PRP83636.1 - 1.1e-09 38.5 0.0 4e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 C2 domain MJ1316 PF04457.12 PRP83637.1 - 2.6e-21 76.1 0.1 3.4e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain Pkinase_Tyr PF07714.17 PRP83641.1 - 2.6e-75 253.1 0.0 3.6e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83641.1 - 1.2e-48 165.8 0.0 2.5e-48 164.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 PRP83641.1 - 1.8e-35 120.4 85.9 1.5e-05 25.3 0.4 16.8 16 1 2 18 18 17 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP83641.1 - 2.8e-35 119.9 100.6 1.5e-07 31.1 1.2 14.6 8 5 9 17 17 17 13 Leucine rich repeat LRR_9 PF14580.6 PRP83641.1 - 8.3e-06 25.4 1.6 0.039 13.5 0.4 4.1 3 1 0 4 4 4 1 Leucine-rich repeat Kinase-like PF14531.6 PRP83641.1 - 2.3e-05 23.9 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_1 PF00560.33 PRP83641.1 - 4.2e-05 23.5 68.8 2.5 9.0 0.1 19.7 24 0 0 24 24 23 3 Leucine Rich Repeat Insulin_TMD PF17870.1 PRP83641.1 - 0.00038 20.4 1.0 0.00038 20.4 1.0 1.9 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment LRR_12 PF18837.1 PRP83641.1 - 0.0094 15.6 0.1 0.0094 15.6 0.1 3.9 4 0 0 4 4 3 1 Leucine-rich repeat LRR_6 PF13516.6 PRP83641.1 - 0.013 15.5 69.7 0.55 10.4 0.1 17.7 22 0 0 22 22 22 0 Leucine Rich repeat Podoplanin PF05808.11 PRP83641.1 - 0.16 12.1 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Podoplanin Nucleoporin_N PF08801.11 PRP83643.1 - 1.5e-50 172.2 2.3 3.8e-50 170.9 2.3 1.7 1 1 0 1 1 1 1 Nup133 N terminal like V-ATPase_C PF03223.15 PRP83643.1 - 0.033 13.6 0.1 0.033 13.6 0.1 1.9 2 0 0 2 2 2 0 V-ATPase subunit C Annexin PF00191.20 PRP83645.1 - 2.2e-75 248.7 6.7 1.3e-21 76.5 0.1 4.5 5 0 0 5 5 5 4 Annexin Acetyltransf_3 PF13302.7 PRP83646.1 - 5.5e-10 40.1 0.3 1.4e-07 32.2 0.3 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MOR2-PAG1_mid PF14228.6 PRP83647.1 - 1.1e-68 231.9 13.0 2.9e-25 88.2 0.3 3.8 2 1 1 4 4 4 3 Cell morphogenesis central region MOR2-PAG1_N PF14222.6 PRP83647.1 - 2.5e-44 152.2 8.3 2.5e-44 152.2 8.3 2.3 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 PRP83647.1 - 2.8e-36 125.7 1.0 1e-35 123.9 1.0 2.0 1 0 0 1 1 1 1 Cell morphogenesis C-terminal Arm PF00514.23 PRP83647.1 - 0.063 13.4 0.1 5.4 7.2 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PRP83647.1 - 0.19 12.1 0.7 87 3.8 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat THUMP PF02926.17 PRP83648.1 - 9.9e-14 51.7 0.1 1.9e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 THUMP domain DOMON PF03351.17 PRP83649.1 - 2.8e-63 211.7 12.9 2.5e-24 85.9 0.3 4.5 4 0 0 4 4 4 3 DOMON domain FAD_binding_4 PF01565.23 PRP83649.1 - 6.2e-27 94.0 4.3 1.4e-26 92.9 4.3 1.7 1 0 0 1 1 1 1 FAD binding domain Ferric_reduct PF01794.19 PRP83649.1 - 5.2e-23 81.5 9.7 5.2e-23 81.5 9.7 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 PRP83649.1 - 6.6e-18 65.3 0.1 1.9e-15 57.3 0.1 2.6 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PRP83649.1 - 2.2e-14 53.5 0.0 4.8e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain BBE PF08031.12 PRP83649.1 - 6.5e-13 48.6 0.2 6.5e-13 48.6 0.2 2.1 2 0 0 2 2 2 1 Berberine and berberine like NAD_binding_1 PF00175.21 PRP83649.1 - 1.4e-06 28.9 0.0 3.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Kei1 PF08552.11 PRP83649.1 - 2.1 8.2 7.1 0.83 9.5 0.3 2.4 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 PTH2 PF01981.16 PRP83650.1 - 2.2e-30 105.3 0.8 3.1e-30 104.8 0.8 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 6PGD PF00393.19 PRP83654.1 - 1.3e-88 297.1 0.1 1.8e-88 296.7 0.1 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 PRP83654.1 - 3.1e-36 124.9 0.0 1.8e-35 122.5 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PRP83654.1 - 1e-05 25.5 0.0 3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PRP83654.1 - 0.00085 19.3 0.0 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 PRP83654.1 - 0.0069 15.8 0.6 0.052 12.9 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 PRP83654.1 - 0.023 14.2 2.0 0.027 14.1 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 PRP83654.1 - 0.036 14.6 0.1 0.32 11.6 0.0 2.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 PRP83654.1 - 0.15 12.5 0.1 34 4.9 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding P2X_receptor PF00864.19 PRP83655.1 - 4.7e-13 49.0 7.5 8.6e-08 31.6 1.9 3.2 2 1 0 2 2 2 2 ATP P2X receptor DUF1624 PF07786.12 PRP83656.1 - 3.9e-08 33.1 1.0 3.9e-08 33.1 1.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 PRP83656.1 - 0.00019 21.0 0.4 0.00019 21.0 0.4 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF5009) DUF2975 PF11188.8 PRP83656.1 - 0.013 15.4 0.1 0.013 15.4 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) WW PF00397.26 PRP83657.1 - 0.066 13.3 2.2 17 5.6 0.0 3.3 3 0 0 3 3 3 0 WW domain SH3_9 PF14604.6 PRP83658.1 - 5.6e-15 54.9 0.9 6.4e-08 32.3 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 PRP83658.1 - 1.1e-14 53.9 0.0 1.3e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PRP83658.1 - 3.3e-14 52.2 0.1 3.1e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 SH3 domain Lebercilin PF15619.6 PRP83658.1 - 0.62 9.7 19.4 0.31 10.7 14.4 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HSD3 PF15244.6 PRP83658.1 - 0.7 9.3 11.7 0.33 10.4 9.5 1.5 1 1 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 AAA_23 PF13476.6 PRP83658.1 - 1.6 9.2 6.0 2.6 8.5 6.0 1.3 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 PRP83658.1 - 2.8 5.7 10.2 4.1 5.2 10.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 PRP83658.1 - 7.4 5.4 9.5 9.8 5.0 9.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rad10 PF03834.14 PRP83659.1 - 2.7e-38 130.5 0.9 5e-38 129.6 0.9 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 PRP83659.1 - 2.5e-07 31.2 0.0 4.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 PRP83659.1 - 9.8e-06 25.6 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 PRP83659.1 - 0.0076 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif ERCC4 PF02732.15 PRP83659.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 ERCC4 domain FAM86 PF14904.6 PRP83659.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function DUF3682 PF12446.8 PRP83660.1 - 0.0019 18.7 2.3 0.097 13.2 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3682) MFMR_assoc PF16596.5 PRP83660.1 - 0.38 11.2 8.0 1.5 9.3 2.9 2.2 2 0 0 2 2 2 0 Disordered region downstream of MFMR CPSase_L_D2 PF02786.17 PRP83661.1 - 9.6e-104 345.5 0.5 8e-78 260.8 0.1 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 PRP83661.1 - 6.7e-45 153.2 0.4 1.5e-44 152.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 PRP83661.1 - 3.9e-44 150.2 0.0 8.3e-44 149.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 PRP83661.1 - 8.7e-41 139.1 0.2 2.3e-40 137.8 0.2 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain PF00988.22 PRP83661.1 - 4.8e-40 136.3 0.0 1.2e-39 135.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Prenylcys_lyase PF07156.14 PRP83661.1 - 4e-37 128.2 0.4 6.9e-37 127.4 0.4 1.3 1 0 0 1 1 1 1 Prenylcysteine lyase OTCace PF00185.24 PRP83661.1 - 1e-33 116.7 0.0 3.3e-33 115.0 0.0 2.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 PRP83661.1 - 1.5e-13 50.8 1.4 1.4e-09 37.8 0.1 2.8 2 1 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PRP83661.1 - 2e-13 50.3 1.3 5.5e-10 39.1 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 PRP83661.1 - 3.2e-13 49.7 0.0 1.6e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain Amidohydro_1 PF01979.20 PRP83661.1 - 4.3e-10 39.4 0.0 3.3e-08 33.2 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family ATPgrasp_Ter PF15632.6 PRP83661.1 - 2.9e-09 36.8 0.1 0.00031 20.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon NAD_binding_8 PF13450.6 PRP83661.1 - 4.9e-06 26.7 0.3 1.6e-05 25.0 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Peptidase_C26 PF07722.13 PRP83661.1 - 8.8e-06 25.6 0.2 0.00016 21.5 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 PRP83661.1 - 1.1e-05 25.6 0.5 0.0043 17.1 0.1 2.7 2 1 0 2 2 2 1 ATP-grasp domain DJ-1_PfpI PF01965.24 PRP83661.1 - 6.6e-05 22.8 0.1 0.0042 16.9 0.1 3.2 3 0 0 3 3 3 1 DJ-1/PfpI family Pyr_redox_2 PF07992.14 PRP83661.1 - 0.051 12.8 0.5 8.8 5.5 0.2 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PAS_8 PF13188.7 PRP83662.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 PRP83662.1 - 0.053 13.8 0.0 0.096 13.0 0.0 1.6 1 1 0 1 1 1 0 PAS domain Ras PF00071.22 PRP83663.1 - 2.6e-46 157.2 0.2 4.5e-46 156.4 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP83663.1 - 3.6e-17 62.7 0.5 4.2e-16 59.3 0.1 2.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP83663.1 - 1.1e-12 47.7 0.1 2e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP83663.1 - 0.0004 20.3 1.4 0.53 10.2 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP83663.1 - 0.0014 18.3 0.3 0.0025 17.4 0.3 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 PRP83663.1 - 0.0056 15.9 0.2 0.22 10.7 0.1 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Vitellogenin_N PF01347.22 PRP83663.1 - 0.042 12.2 0.1 0.058 11.8 0.1 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region NB-ARC PF00931.22 PRP83663.1 - 0.059 12.5 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 PRP83663.1 - 0.076 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 PRP83663.1 - 0.077 13.4 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Nitroreductase PF00881.24 PRP83664.1 - 7.5e-14 52.1 0.0 9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Peptidase_C3G PF12381.8 PRP83664.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Tungro spherical virus-type peptidase Gly_reductase PF09338.11 PRP83664.1 - 0.15 10.4 0.0 0.28 9.5 0.0 1.4 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits Pkinase_Tyr PF07714.17 PRP83665.1 - 6.8e-41 140.3 0.0 9.8e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP83665.1 - 1.1e-29 102.0 81.6 1.9e-05 24.9 3.7 12.8 8 4 3 12 12 12 11 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP83665.1 - 1e-26 93.9 0.0 1.7e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP83665.1 - 4.2e-20 71.3 77.7 1e-05 25.2 3.5 10.8 5 3 4 11 11 11 11 Leucine rich repeat GPS PF01825.21 PRP83665.1 - 1.8e-09 37.9 7.2 4.8e-09 36.6 7.2 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif PRIMA1 PF16101.5 PRP83665.1 - 0.083 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LRR_9 PF14580.6 PRP83665.1 - 0.095 12.2 19.4 2 7.9 1.1 5.1 2 2 3 5 5 5 0 Leucine-rich repeat TMEM154 PF15102.6 PRP83665.1 - 0.14 12.0 0.4 0.37 10.7 0.4 1.6 1 0 0 1 1 1 0 TMEM154 protein family EcKinase PF02958.20 PRP83665.1 - 0.17 11.2 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase bZIP_1 PF00170.21 PRP83666.1 - 5.6e-12 45.6 9.5 5.6e-12 45.6 9.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PRP83666.1 - 3e-09 36.8 7.0 3e-09 36.8 7.0 2.5 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 PRP83666.1 - 1.6e-06 28.5 12.2 3.2e-06 27.5 12.2 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor SOGA PF11365.8 PRP83666.1 - 0.0016 19.5 3.1 0.0018 19.4 0.0 2.4 2 1 1 3 3 3 1 Protein SOGA UPF0242 PF06785.11 PRP83666.1 - 0.0038 17.4 8.6 0.0067 16.6 8.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 PRP83666.1 - 0.0079 16.4 2.5 0.0079 16.4 2.5 1.7 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Terminase_3 PF04466.13 PRP83666.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Phage terminase large subunit HALZ PF02183.18 PRP83666.1 - 0.034 14.4 2.0 0.29 11.4 0.3 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper Tho2 PF11262.8 PRP83666.1 - 0.11 11.7 5.3 0.19 10.9 5.3 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Macoilin PF09726.9 PRP83666.1 - 0.43 9.1 7.3 0.68 8.4 7.3 1.2 1 0 0 1 1 1 0 Macoilin family HAP1_N PF04849.13 PRP83666.1 - 0.45 9.7 10.5 0.71 9.0 10.5 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF5383 PF17355.2 PRP83666.1 - 0.82 10.0 5.4 2.1 8.8 5.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) V_ATPase_I PF01496.19 PRP83666.1 - 1.2 7.0 4.5 1.6 6.5 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AT_hook PF02178.19 PRP83666.1 - 1.6 8.8 5.8 4.2 7.6 5.8 1.7 1 0 0 1 1 1 0 AT hook motif RRM_1 PF00076.22 PRP83667.1 - 1.6e-23 82.3 0.0 4.1e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 PRP83667.1 - 2.8e-17 62.4 0.0 6.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 PRP83667.1 - 5.1e-10 40.0 0.0 9.6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_occluded PF16842.5 PRP83667.1 - 7.8e-07 28.9 0.0 0.015 15.1 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 PRP83667.1 - 0.0051 16.4 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4131 PF13567.6 PRP83668.1 - 0.0012 18.5 2.5 0.0012 18.5 2.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) COPI_assoc PF08507.10 PRP83668.1 - 0.0085 16.1 6.7 0.012 15.6 6.7 1.2 1 0 0 1 1 1 1 COPI associated protein MscS_TM PF12794.7 PRP83668.1 - 0.02 13.8 0.4 0.024 13.5 0.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4022 PF13214.6 PRP83668.1 - 0.13 12.6 4.7 0.1 12.9 2.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4022) DUF2207 PF09972.9 PRP83668.1 - 1.9 7.2 6.1 5 5.8 6.3 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Tetraspanin PF00335.20 PRP83668.1 - 5.9 6.5 14.5 0.11 12.2 4.1 2.1 1 1 1 2 2 2 0 Tetraspanin family RhoGEF PF00621.20 PRP83669.1 - 3.5e-46 157.8 0.2 3.5e-46 157.8 0.2 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 PRP83669.1 - 0.0018 18.5 0.0 0.0018 18.5 0.0 4.5 3 1 0 3 3 3 1 Pleckstrin homology domain DUF2405 PF10293.9 PRP83670.1 - 0.0036 17.3 0.2 0.0036 17.3 0.2 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF2405) SHQ1 PF04925.15 PRP83671.1 - 8.4e-56 188.3 2.4 1.2e-55 187.8 2.4 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 PRP83671.1 - 0.0044 17.4 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain Ribosomal_L21e PF01157.18 PRP83672.1 - 2.5e-45 152.5 2.1 3.5e-45 152.0 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Cep57_MT_bd PF06657.13 PRP83673.1 - 0.00053 20.4 4.4 0.00053 20.4 4.4 4.2 2 1 2 4 4 4 1 Centrosome microtubule-binding domain of Cep57 GAS PF13851.6 PRP83673.1 - 0.00092 18.6 2.7 0.00092 18.6 2.7 3.3 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Bap31_Bap29_C PF18035.1 PRP83673.1 - 0.0079 16.2 0.4 0.0079 16.2 0.4 3.7 2 1 0 3 3 3 2 Bap31/Bap29 cytoplasmic coiled-coil domain DUF5344 PF17279.2 PRP83673.1 - 0.026 15.1 0.3 0.026 15.1 0.3 4.5 5 0 0 5 5 5 0 Family of unknown function (DUF5344) M PF02370.16 PRP83673.1 - 0.22 12.2 0.2 0.22 12.2 0.2 3.5 3 0 0 3 3 3 0 M protein repeat TSC22 PF01166.18 PRP83673.1 - 0.24 11.8 16.7 0.098 13.0 3.5 3.9 3 0 0 3 3 3 0 TSC-22/dip/bun family Cep57_CLD PF14073.6 PRP83673.1 - 2.1 8.3 40.3 1.4 8.9 24.0 4.2 2 1 1 3 3 3 0 Centrosome localisation domain of Cep57 HAP1_N PF04849.13 PRP83673.1 - 4.7 6.3 35.7 1.7 7.8 5.4 3.3 2 1 1 3 3 3 0 HAP1 N-terminal conserved region Yip1 PF04893.17 PRP83674.1 - 5e-10 39.4 11.5 7.2e-10 38.9 11.5 1.3 1 1 0 1 1 1 1 Yip1 domain PRA1 PF03208.19 PRP83674.1 - 0.83 9.3 8.1 0.15 11.6 3.8 1.9 1 1 1 2 2 2 0 PRA1 family protein Nucleoporin_FG PF13634.6 PRP83675.1 - 0.0091 16.8 94.8 0.75 10.7 26.9 5.3 2 1 2 4 4 4 2 Nucleoporin FG repeat region Abhydrolase_2 PF02230.16 PRP83676.1 - 7.5e-19 68.4 0.0 1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase zf-MYND PF01753.18 PRP83676.1 - 1.9e-11 43.8 15.1 4e-11 42.8 15.1 1.6 1 0 0 1 1 1 1 MYND finger Hydrolase_4 PF12146.8 PRP83676.1 - 7.1e-10 38.6 0.0 0.0046 16.2 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 FSH1 PF03959.13 PRP83676.1 - 1.7e-06 27.9 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 PRP83676.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PRP83676.1 - 0.00013 21.6 0.9 0.028 13.9 1.0 2.9 2 1 1 3 3 3 1 Prolyl oligopeptidase family LIP PF03583.14 PRP83676.1 - 0.054 12.8 0.0 0.14 11.5 0.0 1.5 1 1 1 2 2 2 0 Secretory lipase zf-Mss51 PF13824.6 PRP83676.1 - 0.08 13.1 5.1 0.18 11.9 5.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Abhydrolase_6 PF12697.7 PRP83676.1 - 0.15 12.7 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP83676.1 - 0.17 11.5 0.5 12 5.5 0.2 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold RabGAP-TBC PF00566.18 PRP83678.1 - 2e-34 119.1 1.3 2e-34 119.1 1.3 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 PRP83678.1 - 5.1e-21 75.2 0.0 8.8e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83678.1 - 3.8e-15 55.9 0.0 1e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase SH2 PF00017.24 PRP83678.1 - 5.3e-05 23.2 0.2 0.00012 22.1 0.2 1.7 1 0 0 1 1 1 1 SH2 domain Rhodanese PF00581.20 PRP83678.1 - 0.00012 22.6 0.0 0.00036 21.0 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain TSC22 PF01166.18 PRP83679.1 - 0.0078 16.5 2.9 0.0078 16.5 2.9 3.2 3 0 0 3 3 3 1 TSC-22/dip/bun family DUF1844 PF08899.11 PRP83679.1 - 0.19 12.1 2.8 0.27 11.6 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) TMPIT PF07851.13 PRP83679.1 - 0.24 10.6 20.4 0.075 12.3 12.8 2.1 1 1 1 2 2 2 0 TMPIT-like protein FtsL PF04999.13 PRP83679.1 - 0.32 11.0 6.2 3.2 7.8 0.1 2.8 1 1 1 2 2 2 0 Cell division protein FtsL Spc7 PF08317.11 PRP83679.1 - 0.87 8.4 34.7 0.78 8.6 1.0 3.1 1 1 0 3 3 3 0 Spc7 kinetochore protein DUF2205 PF10224.9 PRP83679.1 - 1.2 9.1 11.6 0.64 10.0 7.7 2.6 2 0 0 2 2 2 0 Short coiled-coil protein Fez1 PF06818.15 PRP83679.1 - 1.3 9.4 37.3 2.2 8.7 3.7 3.3 1 1 1 2 2 2 0 Fez1 CEP63 PF17045.5 PRP83679.1 - 4 7.3 35.2 0.34 10.8 2.7 2.5 1 1 0 2 2 2 0 Centrosomal protein of 63 kDa Phage_GP20 PF06810.11 PRP83679.1 - 5 6.9 23.7 1.3 8.8 17.0 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 BLOC1_2 PF10046.9 PRP83679.1 - 5.5 7.4 19.3 0.13 12.6 7.1 3.3 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 PRP83679.1 - 6.8 7.4 28.5 0.32 11.6 5.3 4.5 1 1 3 4 4 4 0 Initiation control protein YabA Nsp1_C PF05064.13 PRP83679.1 - 7.2 6.4 18.2 0.41 10.5 7.0 3.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region APC_N_CC PF16689.5 PRP83679.1 - 7.9 6.6 11.7 8.7 6.5 0.8 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain RhoGEF PF00621.20 PRP83680.1 - 3.6e-48 164.2 4.7 3.6e-48 164.2 4.7 2.2 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 PRP83680.1 - 1.5e-18 67.0 0.0 5e-18 65.3 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain PH_13 PF16652.5 PRP83680.1 - 0.00011 22.1 0.3 0.00011 22.1 0.3 3.0 3 1 1 4 4 4 1 Pleckstrin homology domain PH PF00169.29 PRP83680.1 - 0.00027 21.4 0.1 0.00027 21.4 0.1 3.8 5 1 1 6 6 6 1 PH domain Peptidase_M48 PF01435.18 PRP83681.1 - 3.5e-31 108.5 0.0 9e-31 107.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 Ank_4 PF13637.6 PRP83682.1 - 5.3e-06 26.9 0.0 0.17 12.5 0.0 4.7 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP83682.1 - 0.0049 17.3 0.0 14 6.6 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ig_3 PF13927.6 PRP83682.1 - 0.032 14.8 0.0 4 8.1 0.0 3.6 2 1 0 2 2 2 0 Immunoglobulin domain Ank_5 PF13857.6 PRP83682.1 - 0.033 14.5 0.1 1.3 9.5 0.0 3.5 5 0 0 5 5 5 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP83682.1 - 0.055 14.1 0.0 1.5e+02 3.1 0.0 3.8 2 2 2 4 4 4 0 Ankyrin repeats (3 copies) RabGAP-TBC PF00566.18 PRP83683.1 - 2.2e-45 155.0 0.0 2.7e-44 151.4 0.0 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 PRP83683.1 - 5.9e-24 84.1 0.2 2.3e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 GRAM domain EF-hand_7 PF13499.6 PRP83683.1 - 1.2e-07 32.0 0.5 4.5e-06 27.0 0.5 2.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP83683.1 - 2.2e-05 23.7 0.1 0.031 13.8 0.1 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP83683.1 - 3.1e-05 23.5 0.1 0.028 14.4 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PRP83683.1 - 0.0091 15.8 0.0 2.5 8.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair DUF1902 PF08972.11 PRP83683.1 - 0.15 12.1 0.5 1.4 9.0 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1902) DRMBL PF07522.14 PRP83684.1 - 1.4e-07 31.6 0.1 4.3e-07 30.1 0.1 1.9 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 PRP83684.1 - 0.00053 19.5 0.1 0.022 14.3 0.1 2.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Topo_Zn_Ribbon PF08272.11 PRP83684.1 - 0.069 12.8 0.7 0.19 11.4 0.7 1.8 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Lactamase_B PF00753.27 PRP83684.1 - 0.079 13.0 4.9 1.1 9.3 4.9 2.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Glyco_hydro_130 PF04041.13 PRP83685.1 - 4.1e-30 104.8 0.0 5.8e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase RasGEF PF00617.19 PRP83686.1 - 1.3e-47 162.3 2.4 2.6e-47 161.3 0.6 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP83686.1 - 8.7e-21 74.1 0.9 2.8e-20 72.5 0.9 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif RLAN PF14401.6 PRP83686.1 - 0.61 9.7 2.4 0.6 9.8 0.0 2.2 3 0 0 3 3 3 0 RimK-like ATPgrasp N-terminal domain RSN1_7TM PF02714.15 PRP83687.1 - 6.8e-55 186.3 24.6 6.8e-55 186.3 24.6 2.2 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PRP83687.1 - 2.6e-20 72.8 5.8 2.6e-20 72.8 5.8 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PRP83687.1 - 1.5e-17 64.4 0.2 2.3e-17 63.8 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TrkH PF02386.16 PRP83688.1 - 6e-52 176.7 24.2 1.5e-49 168.9 15.4 2.3 2 0 0 2 2 2 2 Cation transport protein Ribosomal_S13_N PF08069.12 PRP83688.1 - 0.045 13.8 0.2 0.1 12.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain F-box PF00646.33 PRP83690.1 - 9.6e-07 28.5 1.2 1.7e-06 27.7 1.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP83690.1 - 4.9e-05 23.1 0.6 0.0001 22.1 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 PRP83690.1 - 0.075 12.9 0.7 0.13 12.2 0.3 1.6 1 1 0 1 1 1 0 F-box UDPGP PF01704.18 PRP83691.1 - 1.4e-179 597.1 0.0 1.7e-179 596.8 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Cadherin_3 PF16184.5 PRP83692.1 - 9.6e-19 67.4 9.6 0.0025 17.8 0.0 9.5 9 1 1 10 10 10 5 Cadherin-like PTPlike_phytase PF14566.6 PRP83694.1 - 2.1e-130 430.7 0.4 2.4e-51 173.9 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 PRP83694.1 - 1.6e-08 34.5 0.1 0.028 14.2 0.0 3.9 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP83694.1 - 0.0019 17.8 0.0 0.45 10.0 0.0 2.8 3 0 0 3 3 3 2 Protein-tyrosine phosphatase VHL PF01847.16 PRP83694.1 - 0.018 15.0 0.1 17 5.4 0.0 3.6 3 0 0 3 3 3 0 VHL beta domain DUF3430 PF11912.8 PRP83695.1 - 5e-05 23.4 18.1 5.7e-05 23.3 9.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3430) Kinesin PF00225.23 PRP83696.1 - 4.4e-103 344.7 0.0 4.4e-103 344.7 0.0 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PRP83696.1 - 1.7e-47 161.1 0.0 4.8e-47 159.6 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Ank_2 PF12796.7 PRP83696.1 - 2e-17 63.5 0.1 2.7e-07 31.1 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP83696.1 - 6.9e-14 52.0 0.5 0.0046 17.5 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP83696.1 - 2.5e-07 30.5 0.2 1.7 9.4 0.0 5.7 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 PRP83696.1 - 1e-06 28.9 1.4 0.14 12.5 0.0 4.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP83696.1 - 0.00018 21.8 3.3 5.6 7.6 0.0 5.9 5 1 1 6 6 6 1 Ankyrin repeat UPF0137 PF03677.13 PRP83697.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) M16C_assoc PF08367.11 PRP83698.1 - 1e-69 234.5 0.7 1e-69 234.5 0.7 1.6 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 PRP83698.1 - 6.5e-22 78.4 0.0 1.4e-19 70.8 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PRP83698.1 - 1.4e-11 44.5 0.1 6.4e-08 32.7 0.0 2.9 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Homeodomain PF00046.29 PRP83699.1 - 5.3e-16 58.2 5.9 8.2e-16 57.6 5.9 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP83699.1 - 1.5e-07 31.2 3.0 1.6e-07 31.1 1.9 1.7 1 1 1 2 2 2 1 Homeobox KN domain Pkinase_Tyr PF07714.17 PRP83700.1 - 4.1e-65 219.6 0.0 5.8e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83700.1 - 1.3e-51 175.5 0.0 2e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP83700.1 - 1.5e-31 107.9 64.4 1.9e-08 33.9 1.4 10.6 9 1 2 11 11 11 8 Leucine rich repeat Glyco_hydro_18 PF00704.28 PRP83700.1 - 3.7e-26 92.6 2.5 7e-26 91.7 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LRR_4 PF12799.7 PRP83700.1 - 1.9e-23 82.1 78.6 4.5e-07 30.1 3.4 14.7 13 2 2 15 15 15 11 Leucine Rich repeats (2 copies) Kdo PF06293.14 PRP83700.1 - 0.0001 21.7 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP83700.1 - 0.0095 15.9 0.0 2.5 8.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP83700.1 - 0.05 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like LRR_9 PF14580.6 PRP83700.1 - 3 7.3 11.3 0.51 9.8 0.6 3.8 4 0 0 4 4 4 0 Leucine-rich repeat Inositol_P PF00459.25 PRP83701.1 - 4.1e-68 229.8 0.0 1.4e-67 228.1 0.0 1.8 2 0 0 2 2 2 1 Inositol monophosphatase family Methyltransf_32 PF13679.6 PRP83701.1 - 3e-07 30.6 0.0 7.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain zf-CCCH PF00642.24 PRP83701.1 - 0.00069 19.5 1.2 0.0016 18.3 1.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP83701.1 - 0.0011 19.0 1.1 0.0021 18.0 1.1 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 PRP83701.1 - 0.0075 16.7 2.8 0.016 15.7 2.8 1.6 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 PRP83701.1 - 0.012 15.4 1.3 0.022 14.5 1.3 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger CMAS PF02353.20 PRP83701.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DSPc PF00782.20 PRP83702.1 - 7.4e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP83702.1 - 0.00071 19.2 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Formyl_trans_N PF00551.19 PRP83703.1 - 2.6e-26 92.5 0.0 3.6e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 PRP83703.1 - 3.2e-13 49.8 0.0 6.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Cpn60_TCP1 PF00118.24 PRP83704.1 - 5.9e-154 513.3 12.0 8.6e-154 512.8 12.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EamA PF00892.20 PRP83704.1 - 5.4e-30 104.4 35.6 1.1e-15 58.0 10.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family partial_CstF PF15861.5 PRP83704.1 - 0.13 12.0 0.3 0.52 10.1 0.0 2.2 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain zf-LITAF-like PF10601.9 PRP83705.1 - 8.8e-24 83.6 6.5 1.2e-23 83.2 6.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-ISL3 PF14690.6 PRP83705.1 - 0.044 14.5 3.1 5 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DUF2076 PF09849.9 PRP83705.1 - 0.08 13.0 11.2 0.092 12.8 11.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Zn_Tnp_IS1595 PF12760.7 PRP83705.1 - 0.14 12.2 2.8 7.1 6.7 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain GAGA PF09237.11 PRP83705.1 - 0.41 10.5 8.4 0.077 12.8 2.9 2.2 2 0 0 2 2 2 0 GAGA factor Prok-RING_4 PF14447.6 PRP83705.1 - 0.51 10.2 8.7 0.39 10.6 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PRP83705.1 - 1.3 9.0 8.5 7.1 6.6 2.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RBP_receptor PF14752.6 PRP83706.1 - 2.2e-20 72.8 5.0 7.9e-20 71.0 5.0 1.8 1 1 0 1 1 1 1 Retinol binding protein receptor Patatin PF01734.22 PRP83706.1 - 1.2e-18 68.0 2.1 3.2e-17 63.4 0.5 3.1 2 1 0 2 2 2 1 Patatin-like phospholipase Big_1 PF02369.16 PRP83706.1 - 7.2e-10 38.7 4.3 0.033 14.2 0.0 5.8 6 0 0 6 6 6 3 Bacterial Ig-like domain (group 1) MG4 PF17789.1 PRP83706.1 - 2.1e-07 31.0 0.2 19 5.5 0.0 6.9 6 0 0 6 6 6 2 Macroglobulin domain MG4 CarboxypepD_reg PF13620.6 PRP83706.1 - 7.6e-07 29.3 1.3 0.0014 18.9 0.0 4.5 5 0 0 5 5 5 1 Carboxypeptidase regulatory-like domain Glyco_trans_4_3 PF12000.8 PRP83706.1 - 0.065 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 4 group SdrD_B PF17210.3 PRP83706.1 - 0.098 12.9 0.1 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 SdrD B-like domain Exo_endo_phos PF03372.23 PRP83707.1 - 1.7e-13 50.7 0.1 2.2e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_S17e PF00833.18 PRP83708.1 - 3.6e-61 204.5 1.9 4.1e-61 204.3 1.9 1.0 1 0 0 1 1 1 1 Ribosomal S17 FANCI_S2 PF14676.6 PRP83709.1 - 1.6e-15 57.8 0.7 1.6e-15 57.8 0.7 2.3 2 0 0 2 2 2 1 FANCI solenoid 2 GET2 PF08690.10 PRP83709.1 - 0.46 10.1 5.4 0.83 9.3 4.7 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 DUF4407 PF14362.6 PRP83709.1 - 0.51 9.6 2.1 1.2 8.4 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NACHT_N PF17100.5 PRP83709.1 - 0.57 10.0 4.2 1.8 8.4 4.2 1.9 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase CAF1 PF04857.20 PRP83709.1 - 1 8.5 3.2 4.2 6.4 2.2 2.2 2 0 0 2 2 2 0 CAF1 family ribonuclease DNA_pol_phi PF04931.13 PRP83709.1 - 3.1 5.8 12.4 6.5 4.7 12.4 1.5 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_C1 PF00112.23 PRP83710.1 - 1.8e-54 185.1 8.8 2.7e-54 184.6 8.8 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP83710.1 - 2.4e-12 47.1 0.4 4.3e-12 46.3 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP83710.1 - 0.16 10.7 1.8 3.8 6.2 0.2 2.4 3 0 0 3 3 3 0 Peptidase C1-like family TAL_FSA PF00923.19 PRP83711.1 - 3.8e-97 325.1 0.0 4.6e-97 324.8 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Peripla_BP_2 PF01497.18 PRP83712.1 - 0.0002 21.0 0.1 0.0026 17.4 0.1 2.1 1 1 0 1 1 1 1 Periplasmic binding protein Luteo_coat PF00894.18 PRP83712.1 - 0.0086 16.0 0.5 0.019 14.8 0.5 1.5 1 0 0 1 1 1 1 Luteovirus coat protein PIF1 PF05970.14 PRP83713.1 - 3.4e-56 191.0 2.7 7.1e-54 183.4 0.4 2.9 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.6 PRP83713.1 - 3.4e-25 88.9 0.0 5.8e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP83713.1 - 8.3e-11 42.4 0.0 2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PRP83713.1 - 1.7e-05 25.1 0.4 0.00013 22.3 0.0 2.5 3 1 0 3 3 3 1 AAA domain Herpes_Helicase PF02689.14 PRP83713.1 - 3.4e-05 22.0 0.3 0.0074 14.3 0.0 2.4 3 0 0 3 3 3 2 Helicase UvrD_C_2 PF13538.6 PRP83713.1 - 0.00018 21.3 0.0 0.00053 19.8 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 PRP83713.1 - 0.0014 18.1 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PRP83713.1 - 0.0027 17.7 0.0 0.0069 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 PRP83713.1 - 0.0079 16.1 0.2 0.03 14.2 0.2 2.0 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 PRP83713.1 - 0.017 15.5 0.2 0.054 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PRP83713.1 - 0.035 14.5 0.0 0.075 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PRP83713.1 - 0.1 12.5 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 NACHT domain Dynamin_M PF01031.20 PRP83715.1 - 0.012 14.8 0.5 0.014 14.6 0.5 1.1 1 0 0 1 1 1 0 Dynamin central region Linker_histone PF00538.19 PRP83715.1 - 0.13 12.6 0.4 3.7 8.0 0.1 2.5 2 1 1 3 3 3 0 linker histone H1 and H5 family rve PF00665.26 PRP83716.1 - 1.7e-21 76.6 0.0 3.1e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain SF3A2 PF16835.5 PRP83716.1 - 0.075 13.4 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF4286 PF14114.6 PRP83717.1 - 0.044 14.3 0.4 0.22 12.0 0.4 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Pkinase PF00069.25 PRP83718.1 - 5.5e-24 85.0 0.0 7.8e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83718.1 - 3.3e-10 39.7 0.0 5.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP83718.1 - 0.0012 18.8 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP83718.1 - 0.061 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PRP83718.1 - 0.12 11.2 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 PRP83718.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase WD40 PF00400.32 PRP83720.1 - 3.2e-45 151.2 30.4 3.7e-07 30.7 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat BTB_2 PF02214.22 PRP83720.1 - 2e-23 82.5 0.0 8.9e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain Dcc1 PF09724.9 PRP83720.1 - 0.022 14.0 2.4 0.047 13.0 2.4 1.5 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 SnoaL_2 PF12680.7 PRP83720.1 - 0.075 13.7 0.3 2e+02 2.7 0.0 4.5 2 2 2 4 4 4 0 SnoaL-like domain GvpL_GvpF PF06386.11 PRP83720.1 - 1.4 8.8 13.0 0.068 13.1 5.6 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Invasin_D3 PF09134.10 PRP83720.1 - 8.6 6.7 23.3 52 4.2 1.1 5.3 1 1 2 4 4 4 0 Invasin, domain 3 DUF1962 PF09227.10 PRP83720.1 - 9.4 6.7 12.7 5.7 7.4 0.7 4.3 4 2 1 5 5 5 0 Domain of unknown function (DUF1962) WD40 PF00400.32 PRP83722.1 - 1.1e-40 136.9 39.7 4.5e-07 30.5 0.6 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat BTB_2 PF02214.22 PRP83722.1 - 2.6e-08 34.1 0.0 9.9e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain WD40_like PF17005.5 PRP83722.1 - 0.00012 21.6 0.2 0.0017 17.8 0.1 2.2 1 1 1 2 2 2 1 WD40-like domain BBS2_Mid PF14783.6 PRP83722.1 - 0.00027 20.9 0.2 0.2 11.7 0.0 3.9 1 1 4 5 5 5 2 Ciliary BBSome complex subunit 2, middle region RE_AlwI PF09491.10 PRP83722.1 - 0.33 9.7 2.1 0.49 9.1 2.1 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease Invasin_D3 PF09134.10 PRP83722.1 - 0.61 10.4 15.0 5 7.5 0.9 4.7 2 1 3 5 5 4 0 Invasin, domain 3 ATG13 PF10033.9 PRP83723.1 - 1.8e-29 103.1 0.2 1.5e-15 57.6 0.0 2.4 1 1 1 2 2 2 2 Autophagy-related protein 13 EF-hand_8 PF13833.6 PRP83725.1 - 8.8e-12 44.7 0.4 1.2e-10 41.0 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 PRP83725.1 - 6.2e-10 39.4 0.1 7.5e-10 39.1 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP83725.1 - 1.6e-08 33.5 0.5 0.00076 18.9 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP83725.1 - 1.7e-08 33.7 0.1 1.2e-05 24.9 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 PRP83725.1 - 1.1e-05 25.5 0.3 2.7e-05 24.2 0.3 1.7 1 1 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.6 PRP83725.1 - 0.00027 21.2 0.0 0.00033 20.9 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain Vps39_2 PF10367.9 PRP83726.1 - 4.1e-34 117.3 2.9 7.8e-34 116.4 1.7 2.2 2 0 0 2 2 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 PRP83726.1 - 3.6e-31 108.8 0.0 6.7e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 PRP83726.1 - 6.6e-17 61.7 11.1 3e-11 43.4 0.1 4.0 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_1 PF10366.9 PRP83726.1 - 4.3e-14 52.7 2.7 4.3e-14 52.7 2.7 4.2 4 1 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 PPR PF01535.20 PRP83726.1 - 0.0024 18.0 0.9 1.1 9.6 0.1 3.9 4 0 0 4 4 2 1 PPR repeat FlbT PF07378.11 PRP83726.1 - 0.0033 17.5 1.0 0.017 15.2 0.2 2.3 2 0 0 2 2 2 1 Flagellar protein FlbT TPR_19 PF14559.6 PRP83726.1 - 0.0067 16.9 0.9 0.0067 16.9 0.9 3.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP83726.1 - 0.1 12.5 11.6 38 4.3 0.3 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 PRP83726.1 - 0.1 12.6 3.9 0.42 10.7 1.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sdh5 PF03937.16 PRP83726.1 - 0.12 12.4 0.0 4.9 7.2 0.0 3.1 3 0 0 3 3 3 0 Flavinator of succinate dehydrogenase TPR_14 PF13428.6 PRP83726.1 - 0.13 13.1 2.0 20 6.3 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR_2 PF13041.6 PRP83726.1 - 0.29 11.4 2.0 49 4.2 0.3 3.7 3 0 0 3 3 3 0 PPR repeat family Utp13 PF08625.11 PRP83726.1 - 0.6 10.0 5.1 20 5.1 0.2 3.4 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain TPR_2 PF07719.17 PRP83726.1 - 1.1 9.6 9.7 3.2 8.1 0.3 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP83726.1 - 1.3 9.3 4.8 14 6.0 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP83726.1 - 3.6 7.9 10.0 0.96 9.7 1.4 3.8 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase PF00069.25 PRP83727.1 - 4.9e-65 219.5 0.0 5.8e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83727.1 - 1.4e-40 139.3 0.0 1.8e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP83727.1 - 4.1e-10 39.5 0.0 5.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP83727.1 - 7.5e-06 25.4 0.2 1.2e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP83727.1 - 7.3e-05 22.4 0.2 0.00011 21.9 0.2 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 PRP83727.1 - 0.0001 22.3 0.1 0.00028 20.9 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP83727.1 - 0.0013 17.6 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP83727.1 - 0.016 14.1 0.2 0.022 13.7 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain WaaY PF06176.11 PRP83727.1 - 0.019 14.6 0.2 0.027 14.1 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) FTA2 PF13095.6 PRP83727.1 - 0.024 14.3 0.1 0.048 13.3 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 PRP83728.1 - 1.7e-73 247.3 0.0 2e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83728.1 - 9.5e-29 100.4 0.0 1.2e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP83728.1 - 0.00013 21.1 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PRP83728.1 - 0.028 13.7 0.1 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 PRP83728.1 - 0.18 10.5 0.0 0.37 9.5 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase HSF_DNA-bind PF00447.17 PRP83729.1 - 1.7e-28 99.1 1.8 3.5e-28 98.1 1.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.8 PRP83729.1 - 0.00092 19.2 5.2 0.00092 19.2 5.2 1.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 PRP83729.1 - 0.0091 16.1 5.9 0.0091 16.1 5.9 1.8 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 PRP83729.1 - 0.021 14.9 5.7 0.021 14.9 5.7 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 PRP83729.1 - 0.025 15.1 2.4 0.036 14.6 0.1 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region PTRF_SDPR PF15237.6 PRP83729.1 - 0.072 12.7 0.7 0.072 12.7 0.7 2.5 2 1 1 3 3 3 0 PTRF/SDPR family CENP-H PF05837.12 PRP83729.1 - 0.2 12.1 9.0 1.1 9.7 4.3 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF1690 PF07956.11 PRP83729.1 - 2.5 8.5 8.4 17 5.8 4.8 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Peptidase_C1 PF00112.23 PRP83730.1 - 1.3e-46 159.5 3.4 2e-46 158.8 3.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 PRP83730.1 - 6.8e-08 31.7 0.5 0.00012 21.0 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 PRP83730.1 - 1.8e-05 25.0 0.8 3.2e-05 24.3 0.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Ank_4 PF13637.6 PRP83731.1 - 5.6e-28 97.0 10.1 0.0003 21.3 0.0 10.6 5 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP83731.1 - 1.2e-26 93.0 1.3 0.0002 21.9 0.0 7.1 3 2 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP83731.1 - 1e-08 35.3 9.6 0.53 10.7 0.1 9.5 4 3 5 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP83731.1 - 3.2e-08 33.2 2.4 15 6.6 0.0 10.0 14 0 0 14 14 14 1 Ankyrin repeat Ank PF00023.30 PRP83731.1 - 2.1e-06 27.9 15.1 27 5.4 0.1 11.0 10 2 2 12 12 12 1 Ankyrin repeat Glyco_hydro_14 PF01373.17 PRP83732.1 - 1.9e-66 224.7 1.1 8e-66 222.6 1.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 14 eIF-5_eIF-2B PF01873.17 PRP83733.1 - 1.8e-38 131.0 0.1 3.2e-38 130.2 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 CNDH2_C PF16858.5 PRP83733.1 - 0.027 14.3 9.4 0.05 13.5 9.4 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term VAPB_antitox PF02697.14 PRP83733.1 - 0.032 15.0 3.8 0.095 13.5 3.8 1.8 1 0 0 1 1 1 0 Putative antitoxin TPR_2 PF07719.17 PRP83735.1 - 5.4e-27 91.7 10.8 0.0033 17.4 0.1 9.1 8 1 2 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 PRP83735.1 - 1.2e-24 85.1 12.9 7.7e-06 25.5 0.0 8.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 PRP83735.1 - 1.6e-21 74.6 3.7 0.021 15.0 0.0 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 PRP83735.1 - 3.5e-15 55.4 3.3 0.72 10.8 0.0 7.4 6 2 3 9 9 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 PRP83735.1 - 7.1e-13 48.0 0.0 0.18 11.5 0.0 6.8 5 1 1 6 6 6 4 TPR repeat TPR_12 PF13424.6 PRP83735.1 - 1.2e-12 47.9 13.8 0.0056 16.9 0.1 7.1 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP83735.1 - 1.3e-12 48.1 5.1 0.00095 19.8 0.0 5.1 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP83735.1 - 3.8e-12 45.7 13.1 1.2 9.7 0.1 9.5 10 1 0 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP83735.1 - 6.5e-09 35.9 15.3 0.00018 21.7 0.9 5.7 5 1 2 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 PRP83735.1 - 5.2e-08 32.4 4.4 0.15 12.1 0.1 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP83735.1 - 5.6e-08 32.9 11.6 13 6.7 0.6 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83735.1 - 5e-07 30.1 8.2 0.15 12.6 0.1 5.9 3 3 2 7 7 7 1 Tetratricopeptide repeat PknG_TPR PF16918.5 PRP83735.1 - 0.00015 20.6 0.1 0.018 13.8 0.1 2.2 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 PRP83735.1 - 0.0013 18.5 10.0 0.38 10.7 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF5113 PF17140.4 PRP83735.1 - 0.0098 15.7 0.3 0.84 9.4 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF5113) HEAT_2 PF13646.6 PRP83735.1 - 0.0099 16.2 0.1 0.1 13.0 0.0 2.3 1 1 0 2 2 2 1 HEAT repeats TPR_5 PF12688.7 PRP83735.1 - 0.055 13.7 0.1 0.33 11.2 0.1 2.3 2 1 0 2 2 2 0 Tetratrico peptide repeat ChAPs PF09295.10 PRP83735.1 - 0.063 12.3 0.9 0.94 8.4 0.0 2.5 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Sec16_C PF12931.7 PRP83735.1 - 0.11 12.1 2.9 0.34 10.5 0.5 2.2 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 Wzy_C_2 PF11846.8 PRP83735.1 - 3.7 7.4 6.2 6.5 6.6 0.0 3.6 2 2 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Nudix_N_2 PF14803.6 PRP83736.1 - 0.021 14.8 2.1 0.021 14.8 2.1 2.6 2 1 0 2 2 2 0 Nudix N-terminal DZR PF12773.7 PRP83736.1 - 0.079 13.0 7.3 0.16 12.0 7.3 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 PRP83736.1 - 0.13 11.7 7.5 0.09 12.2 2.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 PRP83736.1 - 2 8.5 8.5 0.23 11.4 1.3 2.2 1 1 1 2 2 2 0 zinc-ribbons Sec23_trunk PF04811.15 PRP83737.1 - 1.8e-64 217.6 0.0 2.8e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PRP83737.1 - 2.6e-31 108.2 0.1 5.5e-31 107.2 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 PRP83737.1 - 1.5e-24 85.8 0.2 3.3e-24 84.7 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PRP83737.1 - 6.9e-14 51.6 6.9 1.3e-13 50.7 6.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 PRP83737.1 - 1.2e-12 47.6 0.0 2.5e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 PRP83737.1 - 0.018 14.4 0.2 0.045 13.1 0.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain WD40 PF00400.32 PRP83738.1 - 1e-32 111.6 33.5 1.6e-05 25.5 0.6 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat BTB_2 PF02214.22 PRP83738.1 - 3.7e-20 72.1 0.0 8.5e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain BBS2_Mid PF14783.6 PRP83738.1 - 4.6e-05 23.4 0.1 0.53 10.4 0.0 3.5 2 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region SnoaL_2 PF12680.7 PRP83738.1 - 0.0038 17.8 0.5 5 7.8 0.0 3.9 3 1 1 4 4 4 1 SnoaL-like domain Nup160 PF11715.8 PRP83738.1 - 0.076 11.6 4.1 1.4 7.4 0.6 3.2 2 2 1 3 3 3 0 Nucleoporin Nup120/160 DUF769 PF05590.11 PRP83738.1 - 0.29 10.5 3.0 6 6.2 0.0 3.2 2 1 0 3 3 3 0 Xylella fastidiosa protein of unknown function (DUF769) Calx-beta PF03160.14 PRP83738.1 - 0.3 11.3 1.9 6.9 6.9 0.0 3.6 4 0 0 4 4 4 0 Calx-beta domain Invasin_D3 PF09134.10 PRP83738.1 - 3.7 7.9 12.8 27 5.1 0.2 4.4 1 1 2 4 4 4 0 Invasin, domain 3 DEC-1_N PF04625.13 PRP83738.1 - 5.6 5.9 6.2 0.55 9.2 0.6 1.9 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region TPR_2 PF07719.17 PRP83739.1 - 3e-34 114.4 11.5 0.004 17.2 0.0 12.3 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 PRP83739.1 - 2.1e-31 106.4 6.5 0.0079 16.0 0.0 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 PRP83739.1 - 7.2e-29 97.6 14.0 0.0051 16.9 0.0 11.3 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83739.1 - 6e-23 81.1 20.9 0.0043 17.5 0.1 8.0 5 1 2 8 8 8 8 Tetratricopeptide repeat TPR_16 PF13432.6 PRP83739.1 - 9.3e-17 61.4 4.2 0.0047 17.6 0.0 7.3 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 PRP83739.1 - 1.1e-16 60.7 7.6 0.47 10.6 0.1 8.5 3 2 4 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 PRP83739.1 - 2.7e-16 58.9 5.0 0.067 12.9 0.0 8.9 8 1 1 9 9 9 3 TPR repeat TPR_14 PF13428.6 PRP83739.1 - 8.3e-16 57.3 12.4 0.054 14.3 0.0 9.8 6 2 5 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 PRP83739.1 - 5.7e-14 52.2 17.4 0.0044 17.3 0.0 7.7 5 2 2 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP83739.1 - 3.2e-11 43.3 7.9 0.051 13.8 0.1 7.0 4 2 4 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PRP83739.1 - 2.4e-10 40.0 2.3 0.21 12.0 0.0 8.7 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP83739.1 - 8.4e-10 38.0 8.7 0.19 11.8 0.0 8.8 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 PRP83739.1 - 4.2e-09 36.0 10.5 0.002 17.4 2.3 5.3 2 2 2 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 PRP83739.1 - 2.1e-08 33.5 4.5 0.01 14.8 0.1 4.3 3 2 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 PRP83739.1 - 1.4e-06 27.9 12.8 5.1 7.1 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF3856 PF12968.7 PRP83739.1 - 1.7e-05 24.9 1.4 0.11 12.5 0.1 4.7 3 2 1 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 PRP83739.1 - 3.5e-05 24.2 16.3 8.5 7.3 0.1 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 PRP83739.1 - 8e-05 22.0 2.3 0.52 9.8 0.0 5.1 6 0 0 6 6 6 1 SHNi-TPR BTAD PF03704.17 PRP83739.1 - 0.00015 22.3 13.6 0.16 12.4 0.8 5.2 3 3 1 4 4 4 2 Bacterial transcriptional activator domain YcaO_C PF18381.1 PRP83739.1 - 0.011 15.6 0.8 27 4.6 0.1 4.2 3 2 1 4 4 4 0 YcaO cyclodehydratase C-terminal domain TPR_5 PF12688.7 PRP83739.1 - 0.023 14.9 6.7 0.95 9.7 0.2 4.4 4 1 1 5 5 5 0 Tetratrico peptide repeat GldM_N PF12081.8 PRP83739.1 - 0.024 14.7 2.3 0.05 13.7 0.4 2.3 2 0 0 2 2 2 0 GldM N-terminal domain Ku_PK_bind PF08785.11 PRP83739.1 - 0.058 13.5 1.9 2.6 8.2 0.1 3.6 4 0 0 4 4 4 0 Ku C terminal domain like NRBF2_MIT PF17169.4 PRP83739.1 - 0.081 13.2 0.6 1.7 8.9 0.0 3.1 3 0 0 3 3 3 0 MIT domain of nuclear receptor-binding factor 2 HsbA PF12296.8 PRP83739.1 - 0.12 12.9 0.3 1.3 9.5 0.0 2.8 4 0 0 4 4 3 0 Hydrophobic surface binding protein A ANAPC5 PF12862.7 PRP83739.1 - 0.13 12.3 6.9 53 4.0 0.0 5.2 4 3 1 5 5 4 0 Anaphase-promoting complex subunit 5 DUF2408 PF10303.9 PRP83739.1 - 0.24 12.0 7.4 0.38 11.3 3.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Coatomer_E PF04733.14 PRP83739.1 - 0.3 10.5 9.5 0.49 9.8 0.5 3.2 3 0 0 3 3 3 0 Coatomer epsilon subunit LRR_4 PF12799.7 PRP83741.1 - 7.3e-15 54.8 16.2 3.2e-05 24.2 0.6 5.3 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP83741.1 - 1.4e-06 27.9 12.7 0.0021 17.8 1.2 3.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 PRP83741.1 - 1.5e-06 27.8 1.7 0.026 14.0 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat SCAB-Ig PF16709.5 PRP83741.1 - 0.0011 18.9 0.0 0.26 11.4 0.0 3.9 3 0 0 3 3 3 1 Ig domain of plant-specific actin-binding protein LRR_6 PF13516.6 PRP83741.1 - 0.0091 16.0 5.4 9.2 6.6 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 PRP83741.1 - 0.08 13.5 2.9 43 5.2 0.1 5.4 3 2 0 3 3 3 0 Leucine Rich Repeat RRM_1 PF00076.22 PRP83742.1 - 4.2e-19 68.1 0.1 7.4e-19 67.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 PRP83742.1 - 3.4e-14 53.2 2.0 3.4e-14 53.2 2.0 2.4 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_7 PF16367.5 PRP83742.1 - 0.047 13.8 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 RNA recognition motif Ctf8 PF09696.10 PRP83743.1 - 1.3e-08 35.2 0.1 4e-08 33.7 0.1 1.8 1 1 0 1 1 1 1 Ctf8 Chlam_PMP PF02415.17 PRP83743.1 - 0.009 16.4 0.6 0.03 14.8 0.6 2.0 1 0 0 1 1 1 1 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Thioredoxin PF00085.20 PRP83744.1 - 8.9e-26 89.9 0.0 1.3e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PRP83744.1 - 1.7e-05 25.2 0.0 0.00012 22.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 PRP83744.1 - 4.8e-05 23.1 0.0 9.1e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 PRP83744.1 - 6.9e-05 22.8 0.0 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin domain DUF836 PF05768.14 PRP83744.1 - 0.00016 22.0 0.0 0.00029 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.6 PRP83744.1 - 0.00025 21.2 0.0 0.00062 19.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like KaiB PF07689.12 PRP83744.1 - 0.00038 20.1 0.0 0.00095 18.9 0.0 1.6 1 0 0 1 1 1 1 KaiB domain Thioredoxin_8 PF13905.6 PRP83744.1 - 0.013 15.8 0.1 0.17 12.2 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 PRP83744.1 - 0.015 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 PRP83744.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3105 PF11303.8 PRP83744.1 - 0.086 13.0 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) AAA PF00004.29 PRP83745.1 - 7.2e-40 136.5 0.0 1.5e-39 135.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 PRP83745.1 - 1.2e-07 31.6 0.8 9.3e-07 28.8 0.1 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 PRP83745.1 - 3.3e-07 30.0 0.0 9.6e-07 28.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 PRP83745.1 - 9.7e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PRP83745.1 - 8.3e-05 22.9 0.6 0.012 15.9 0.1 2.9 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 PRP83745.1 - 8.9e-05 22.5 0.5 0.00028 20.9 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PRP83745.1 - 0.00012 21.4 0.0 0.00035 19.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 PRP83745.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 PRP83745.1 - 0.0024 18.0 1.2 0.007 16.5 0.0 2.4 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PRP83745.1 - 0.0056 17.1 0.1 0.028 14.8 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 PRP83745.1 - 0.0081 15.6 0.1 0.017 14.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PRP83745.1 - 0.028 14.1 0.0 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 PRP83745.1 - 0.03 13.9 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PRP83745.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PRP83745.1 - 0.048 14.2 0.0 0.048 14.2 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.6 PRP83745.1 - 0.053 13.8 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 PRP83745.1 - 0.055 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 PRP83745.1 - 0.058 12.8 0.0 9.2 5.6 0.0 2.9 1 1 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 PRP83745.1 - 0.062 12.8 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 PRP83745.1 - 0.099 13.0 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 PRP83745.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 PRP83745.1 - 0.12 11.7 0.6 1.3 8.3 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.11 PRP83745.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PRP83745.1 - 0.23 11.7 1.8 0.43 10.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain RCC1_2 PF13540.6 PRP83746.1 - 1.8e-15 56.3 12.0 2.5e-05 23.9 0.1 5.9 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 PRP83746.1 - 1.9e-11 44.4 10.9 1.4e-05 25.6 0.0 6.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 PRP83746.1 - 6.5e-10 39.2 0.1 1.1e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 BTB/POZ domain LRR_8 PF13855.6 PRP83746.1 - 8.3e-08 31.9 1.6 3.4e-07 29.9 1.6 2.1 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PRP83746.1 - 1.3e-06 28.6 0.1 8.3e-06 26.1 0.1 2.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) Filamin PF00630.19 PRP83746.1 - 6.4e-05 23.7 0.0 0.00014 22.6 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat MgtE_N PF03448.17 PRP83746.1 - 0.058 14.0 0.3 1.3 9.7 0.6 2.7 2 0 0 2 2 2 0 MgtE intracellular N domain LRR_9 PF14580.6 PRP83746.1 - 0.099 12.1 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeat Neur_chan_LBD PF02931.23 PRP83747.1 - 0.048 13.1 0.0 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel ligand binding domain Chitin_bind_1 PF00187.19 PRP83748.1 - 5.3e-07 30.0 18.2 5.3e-07 30.0 18.2 2.5 3 0 0 3 3 3 1 Chitin recognition protein T7SS_ESX_EspC PF10824.8 PRP83749.1 - 4.3 7.9 14.2 2 9.0 4.3 2.1 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm Kinesin PF00225.23 PRP83750.1 - 1e-97 327.1 1.7 1e-97 327.1 1.7 2.5 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP83750.1 - 1.1e-22 80.6 0.3 6.8e-21 74.8 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding Wtap PF17098.5 PRP83750.1 - 0.014 15.3 6.4 0.034 14.1 6.4 1.6 1 0 0 1 1 1 0 WTAP/Mum2p family Peptidase_C1 PF00112.23 PRP83752.1 - 3.1e-46 158.2 5.6 3.1e-46 158.2 5.6 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 PRP83752.1 - 5e-07 28.8 1.2 0.00055 18.8 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family PAN_4 PF14295.6 PRP83752.1 - 2.3e-06 27.4 4.0 9.5e-06 25.4 4.0 2.2 1 0 0 1 1 1 1 PAN domain SDA1 PF05285.12 PRP83752.1 - 5.1e-05 22.9 24.2 9.6e-05 22.0 24.2 1.3 1 0 0 1 1 1 1 SDA1 Inhibitor_I29 PF08246.12 PRP83752.1 - 0.00024 21.5 3.0 0.00059 20.2 3.0 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PAN_1 PF00024.26 PRP83752.1 - 0.00047 20.1 3.5 0.00071 19.5 2.0 2.1 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.11 PRP83752.1 - 0.0016 18.6 0.6 0.0016 18.6 0.6 2.4 2 0 0 2 2 2 1 PAN-like domain CDC45 PF02724.14 PRP83752.1 - 0.014 13.8 14.0 0.021 13.1 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 PRP83752.1 - 0.074 11.8 8.0 0.14 10.9 8.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 PRP83752.1 - 0.5 8.5 30.7 0.78 7.9 30.7 1.2 1 0 0 1 1 1 0 Nop14-like family MANEC PF07502.14 PRP83752.1 - 1.1 9.6 6.5 2.9 8.2 3.1 2.6 2 0 0 2 2 2 0 MANEC domain DUF913 PF06025.12 PRP83752.1 - 5.6 5.8 7.8 17 4.2 7.8 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.6 PRP83752.1 - 5.7 5.6 7.8 9.4 4.9 7.8 1.2 1 0 0 1 1 1 0 Raftlin Peptidase_S64 PF08192.11 PRP83752.1 - 8.7 4.7 9.9 15 3.9 9.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Rad52_Rad22 PF04098.15 PRP83753.1 - 2.1e-48 164.1 0.9 3.2e-48 163.5 0.9 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein TFIIA PF03153.13 PRP83753.1 - 3.1 7.7 24.1 3.9 7.4 24.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 PRP83753.1 - 4.5 6.7 11.3 5.9 6.4 11.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FlgT_N PF16548.5 PRP83753.1 - 8.7 7.0 10.3 0.44 11.1 2.7 2.5 2 1 1 3 3 3 0 Flagellar assembly protein T, N-terminal domain IRK_C PF17655.1 PRP83754.1 - 1.2e-23 83.6 0.1 7.8e-20 71.2 0.1 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PRP83754.1 - 0.00041 20.2 0.3 0.00069 19.4 0.3 1.3 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 PRP83754.1 - 0.0031 17.5 2.8 0.0049 16.8 2.8 1.3 1 0 0 1 1 1 1 Ion channel DRMBL PF07522.14 PRP83754.1 - 0.099 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase DUF2518 PF10726.9 PRP83755.1 - 0.21 11.3 2.1 3.8 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) Clathrin_H_link PF13838.6 PRP83756.1 - 0.0071 16.2 0.3 0.026 14.4 0.1 1.8 2 0 0 2 2 2 1 Clathrin-H-link RXT2_N PF08595.11 PRP83756.1 - 0.45 10.5 8.4 0.33 11.0 6.2 1.7 1 1 1 2 2 2 0 RXT2-like, N-terminal ELMO_CED12 PF04727.13 PRP83757.1 - 1.1e-40 139.6 0.0 3.5e-40 138.0 0.0 1.9 1 0 0 1 1 1 1 ELMO/CED-12 family C2 PF00168.30 PRP83757.1 - 0.00016 21.9 0.0 0.27 11.5 0.0 2.8 2 0 0 2 2 2 2 C2 domain SH2 PF00017.24 PRP83757.1 - 0.0028 17.7 0.5 0.035 14.2 0.0 3.1 3 0 0 3 3 3 1 SH2 domain DUF4497 PF14924.6 PRP83757.1 - 0.051 14.1 0.7 1.4 9.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4497) Sporozoite_P67 PF05642.11 PRP83757.1 - 1.2 7.1 15.8 2.1 6.3 15.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FUSC PF04632.12 PRP83757.1 - 1.3 7.5 4.6 0.73 8.3 2.7 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family BCS1_N PF08740.11 PRP83758.1 - 4.6e-35 121.3 0.0 1.1e-34 120.0 0.0 1.7 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 PRP83758.1 - 2.2e-17 63.7 0.0 4.1e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 PRP83758.1 - 6.2e-11 42.7 0.9 0.0019 19.0 0.2 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP83758.1 - 8.6e-11 42.0 0.0 0.048 14.0 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF815 PF05673.13 PRP83758.1 - 6.2e-06 25.6 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Ge1_WD40 PF16529.5 PRP83758.1 - 0.00014 20.9 0.1 0.01 14.9 0.0 2.3 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PRP83758.1 - 0.00016 21.5 0.2 0.93 9.5 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat AAA_25 PF13481.6 PRP83758.1 - 0.0061 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Alpha-amyl_C PF09071.10 PRP83758.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Alpha-amylase, C terminal Nbas_N PF15492.6 PRP83758.1 - 0.086 12.2 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.6 PRP83758.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain BK_channel_a PF03493.18 PRP83760.1 - 1.2e-19 70.3 0.0 5.3e-19 68.2 0.0 2.2 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PRP83760.1 - 5.1e-13 48.8 4.0 1.3e-12 47.4 4.0 1.8 1 0 0 1 1 1 1 Ion channel RhoGEF PF00621.20 PRP83761.1 - 3.7e-49 167.4 2.0 1.1e-47 162.7 0.9 2.3 2 0 0 2 2 2 1 RhoGEF domain Arm PF00514.23 PRP83761.1 - 5.4e-14 51.7 14.2 0.00047 20.1 0.1 7.2 7 1 0 7 7 7 4 Armadillo/beta-catenin-like repeat PH PF00169.29 PRP83761.1 - 4.8e-06 27.0 0.1 1.5e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 PH domain DUF3361 PF11841.8 PRP83761.1 - 0.0057 16.6 20.9 0.13 12.2 0.3 4.8 3 1 2 5 5 5 2 Domain of unknown function (DUF3361) HEAT_2 PF13646.6 PRP83761.1 - 0.034 14.5 0.4 13 6.3 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats Rab_bind PF16704.5 PRP83761.1 - 0.059 13.4 3.0 0.19 11.8 0.7 2.5 2 0 0 2 2 2 0 Rab binding domain UNC45-central PF11701.8 PRP83761.1 - 0.097 12.6 1.5 3.5 7.6 0.1 3.0 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Herpes_DNAp_acc PF04929.12 PRP83761.1 - 1.2 8.0 7.4 2.2 7.2 7.4 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor rve PF00665.26 PRP83763.1 - 3.8e-08 33.5 0.0 9.4e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF4125 PF13526.6 PRP83763.1 - 0.042 13.4 0.2 0.12 12.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) Carn_acyltransf PF00755.20 PRP83764.1 - 1.4e-86 291.5 0.0 1.6e-86 291.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase MORN PF02493.20 PRP83765.1 - 1.8e-08 33.8 22.1 0.00095 18.9 1.0 6.2 5 0 0 5 5 5 5 MORN repeat MIP PF00230.20 PRP83766.1 - 3.2e-31 108.8 7.7 4.3e-31 108.4 7.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF4045 PF13254.6 PRP83766.1 - 0.02 14.6 17.2 0.045 13.4 17.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF368 PF04018.13 PRP83766.1 - 0.066 12.8 1.3 0.12 11.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF368) CDC45 PF02724.14 PRP83766.1 - 0.13 10.6 34.7 0.22 9.8 34.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Borrelia_P83 PF05262.11 PRP83766.1 - 0.25 9.8 26.5 0.37 9.2 26.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 PRP83766.1 - 2.5 6.8 26.2 4.7 5.9 26.2 1.4 1 0 0 1 1 1 0 Presenilin MCM PF00493.23 PRP83767.1 - 7e-95 316.4 0.0 1e-94 315.8 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PRP83767.1 - 5.1e-29 100.7 0.5 1.1e-28 99.6 0.5 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PRP83767.1 - 1.2e-20 73.8 0.7 2.8e-20 72.5 0.7 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PRP83767.1 - 1.7e-11 44.6 3.1 6.3e-11 42.8 1.9 2.4 2 1 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 PRP83767.1 - 7.4e-09 35.7 0.0 9.6e-08 32.1 0.0 2.9 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PRP83767.1 - 9e-08 31.7 0.2 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PRP83767.1 - 0.0052 16.6 0.0 0.023 14.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PRP83767.1 - 0.092 12.4 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain PIG-S PF10510.9 PRP83767.1 - 0.094 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein AAA_16 PF13191.6 PRP83767.1 - 1.4 9.3 4.9 1.4 9.3 0.1 2.8 2 2 0 2 2 2 0 AAA ATPase domain PB1 PF00564.24 PRP83770.1 - 1.5e-08 34.5 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 PB1 domain baeRF_family11 PF18855.1 PRP83770.1 - 0.047 14.0 0.0 2.1 8.6 0.0 2.1 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 11 WSC PF01822.19 PRP83771.1 - 2.8e-51 171.6 74.3 4.5e-15 55.6 10.2 5.3 5 0 0 5 5 5 4 WSC domain PQQ_3 PF13570.6 PRP83771.1 - 6.8e-05 23.2 2.6 0.035 14.6 0.2 4.3 3 0 0 3 3 3 1 PQQ-like domain DUF1573 PF07610.11 PRP83771.1 - 0.00014 21.8 3.2 0.082 12.9 0.0 4.0 4 1 0 4 4 4 2 Protein of unknown function (DUF1573) SPX PF03105.19 PRP83771.1 - 6.5 6.6 10.7 9.6 6.0 10.7 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 PRP83771.1 - 7.4 5.6 21.1 11 5.0 21.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 PRP83772.1 - 1.8e-41 142.2 0.0 1e-40 139.8 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83772.1 - 2.7e-20 72.8 0.0 3.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP83772.1 - 2.1e-07 31.1 0.1 7.7e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP83772.1 - 4e-05 23.1 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP83772.1 - 0.0031 16.9 0.0 0.93 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PRP83772.1 - 0.026 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 PRP83772.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 PRP83772.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain La PF05383.17 PRP83773.1 - 2.6e-19 69.0 0.1 2.6e-19 69.0 0.1 1.9 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 PRP83773.1 - 1.5e-11 44.0 0.0 3.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPS PF01825.21 PRP83773.1 - 1.8e-11 44.4 2.8 1.8e-11 44.4 2.8 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP83773.1 - 1.2e-10 41.2 0.0 3.4e-08 33.1 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP83773.1 - 1.7e-10 40.7 0.2 2.8e-07 30.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain SUZ-C PF12901.7 PRP83773.1 - 0.0018 18.3 1.6 0.0048 16.9 1.6 1.7 1 0 0 1 1 1 1 SUZ-C motif Snf7 PF03357.21 PRP83773.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Snf7 YajC PF02699.15 PRP83773.1 - 0.28 11.1 1.5 17 5.4 0.4 3.3 3 0 0 3 3 3 0 Preprotein translocase subunit adh_short PF00106.25 PRP83774.1 - 9.5e-29 100.2 0.0 1.3e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP83774.1 - 1.6e-24 86.8 0.0 2.1e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP83774.1 - 0.00097 19.1 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Kinesin PF00225.23 PRP83775.1 - 2e-106 355.7 0.1 2e-106 355.7 0.1 4.6 4 2 1 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 PRP83775.1 - 2.3e-49 167.2 0.0 2.3e-49 167.2 0.0 3.9 3 1 0 3 3 3 1 Microtubule binding DLH PF01738.18 PRP83775.1 - 1.7e-19 70.3 0.3 3.5e-17 62.7 0.0 3.8 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF2401 PF10287.9 PRP83776.1 - 2.1e-40 138.7 0.0 3.3e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 PRP83776.1 - 0.017 15.6 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Glycine-rich protein domain (DUF2403) EGF_2 PF07974.13 PRP83778.1 - 0.038 14.4 3.3 0.073 13.4 3.3 1.4 1 0 0 1 1 1 0 EGF-like domain Holin_SPP1 PF04688.13 PRP83778.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 SPP1 phage holin SLATT_4 PF18186.1 PRP83778.1 - 1.6 8.3 3.7 4.3 7.0 0.3 2.8 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 EGF_2 PF07974.13 PRP83779.1 - 0.02 15.2 3.4 0.043 14.2 3.4 1.5 1 0 0 1 1 1 0 EGF-like domain Glt_symporter PF03616.14 PRP83780.1 - 0.00043 19.1 19.0 0.00057 18.7 1.8 2.7 3 0 0 3 3 3 2 Sodium/glutamate symporter Asp_Glu_race PF01177.22 PRP83780.1 - 0.0024 17.7 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 2 Asp/Glu/Hydantoin racemase RPM2 PF08579.11 PRP83780.1 - 0.054 13.9 0.9 1.5 9.2 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) EGF_2 PF07974.13 PRP83780.1 - 0.19 12.1 7.2 0.41 11.0 7.2 1.5 1 0 0 1 1 1 0 EGF-like domain HrcA_DNA-bdg PF03444.15 PRP83780.1 - 0.21 11.3 0.7 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding PGK PF00162.19 PRP83781.1 - 2.5e-150 500.6 4.7 3.4e-150 500.2 4.7 1.2 1 0 0 1 1 1 1 Phosphoglycerate kinase DnaJ PF00226.31 PRP83781.1 - 1.8e-20 72.8 0.6 4.2e-20 71.6 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Ldh_1_C PF02866.18 PRP83782.1 - 2.8e-42 144.5 0.1 4e-42 144.0 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PRP83782.1 - 1.1e-39 135.7 0.5 1.9e-39 135.0 0.5 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 PRP83782.1 - 0.031 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Carb_bind PF10645.9 PRP83782.1 - 1.3 9.3 11.7 0.41 10.9 1.5 2.4 2 0 0 2 2 2 0 Carbohydrate binding ParA PF10609.9 PRP83783.1 - 2.5e-93 312.1 0.1 3.5e-93 311.6 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 PRP83783.1 - 3e-14 53.2 0.0 9.5e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PRP83783.1 - 6.4e-11 42.5 0.5 1.4e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 PRP83783.1 - 2.8e-09 36.8 0.0 9.6e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Homeodomain PF00046.29 PRP83783.1 - 1e-08 34.9 0.9 0.0036 17.1 0.0 2.5 1 1 1 2 2 2 2 Homeodomain MipZ PF09140.11 PRP83783.1 - 3.9e-07 29.6 0.0 7.3e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 PRP83783.1 - 3e-05 23.3 0.2 0.00023 20.4 0.2 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 PRP83783.1 - 5.7e-05 22.5 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein AAA_25 PF13481.6 PRP83783.1 - 0.00028 20.5 0.0 0.00064 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 PRP83783.1 - 0.019 14.8 0.0 0.098 12.4 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRP54 PF00448.22 PRP83783.1 - 0.026 14.2 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Snf7 PF03357.21 PRP83784.1 - 5.2e-31 107.6 18.4 6.3e-31 107.3 18.4 1.0 1 0 0 1 1 1 1 Snf7 TraB PF01963.17 PRP83784.1 - 0.092 12.6 5.7 0.12 12.3 5.7 1.3 1 0 0 1 1 1 0 TraB family Vps39_2 PF10367.9 PRP83784.1 - 0.14 12.6 0.3 0.14 12.6 0.3 2.2 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Vps54_N PF10475.9 PRP83784.1 - 0.87 8.8 7.4 1.2 8.3 6.9 1.4 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DbpA PF03880.15 PRP83785.1 - 0.0057 16.6 0.1 0.5 10.4 0.0 2.7 2 0 0 2 2 2 1 DbpA RNA binding domain CCAP PF11105.8 PRP83785.1 - 0.17 11.8 0.8 0.86 9.6 0.1 2.5 3 0 0 3 3 3 0 Arthropod cardioacceleratory peptide 2a KaiA PF07688.12 PRP83785.1 - 0.24 11.5 2.0 0.44 10.7 0.3 2.3 2 0 0 2 2 2 0 KaiA C-terminal domain Homeodomain PF00046.29 PRP83786.1 - 6.1e-09 35.6 3.6 0.002 17.9 0.3 3.6 4 0 0 4 4 4 2 Homeodomain Homez PF11569.8 PRP83786.1 - 0.0024 17.3 0.0 0.0058 16.1 0.0 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HAUS4 PF14735.6 PRP83786.1 - 0.036 13.8 0.2 0.14 11.9 0.2 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 YdaS_antitoxin PF15943.5 PRP83786.1 - 0.069 13.0 0.1 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 PRP83786.1 - 0.082 12.8 1.9 0.76 9.7 0.5 2.6 2 0 0 2 2 2 0 Homeobox KN domain ECH_1 PF00378.20 PRP83787.1 - 1.5e-50 171.9 0.2 4e-50 170.5 0.1 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP83787.1 - 7.6e-31 107.8 11.6 2.8e-27 96.1 0.1 2.9 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase Homeodomain PF00046.29 PRP83787.1 - 0.00093 19.0 1.7 0.0048 16.7 0.0 2.5 2 0 0 2 2 2 1 Homeodomain DUF724 PF05266.14 PRP83787.1 - 0.0098 15.7 1.3 0.0098 15.7 1.3 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF724) WD40 PF00400.32 PRP83787.1 - 0.017 16.0 0.2 0.017 16.0 0.2 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat RP-C_C PF11800.8 PRP83787.1 - 0.39 10.8 9.5 0.99 9.5 9.5 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region SLC12 PF03522.15 PRP83787.1 - 0.97 8.4 17.0 2 7.4 17.0 1.4 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 PRP83787.1 - 1.1 9.4 6.1 2.3 8.3 6.1 1.6 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.7 PRP83787.1 - 2.6 6.1 13.5 3.9 5.5 13.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 PRP83787.1 - 3 7.0 11.9 5.8 6.0 11.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Met_10 PF02475.16 PRP83788.1 - 3.7e-46 157.4 0.0 6.6e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 PRP83788.1 - 0.036 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 PRP83788.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PSS PF03034.15 PRP83789.1 - 1.5e-80 270.9 15.1 2.5e-61 207.8 13.7 2.6 2 1 1 3 3 3 2 Phosphatidyl serine synthase NAD_Gly3P_dh_N PF01210.23 PRP83790.1 - 6.5e-49 165.9 0.0 1.5e-48 164.8 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 PRP83790.1 - 1.3e-44 151.9 0.3 2.3e-44 151.1 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Methyltransf_11 PF08241.12 PRP83790.1 - 5.6e-13 49.4 0.0 1.7e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP83790.1 - 1.8e-10 41.3 0.0 2.2e-09 37.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP83790.1 - 6.2e-10 39.1 0.0 3e-08 33.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PRP83790.1 - 0.0076 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain F420_oxidored PF03807.17 PRP83790.1 - 0.0084 16.7 0.3 2.9 8.5 0.1 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Ubie_methyltran PF01209.18 PRP83790.1 - 0.031 13.6 0.0 4.1 6.7 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family EXS PF03124.14 PRP83791.1 - 1.7e-81 274.2 39.1 4.4e-71 239.9 28.8 2.9 2 1 1 3 3 3 2 EXS family Band_7 PF01145.25 PRP83791.1 - 1.4e-17 64.3 0.1 2.8e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family SPX PF03105.19 PRP83791.1 - 2.1e-06 27.9 3.8 0.00047 20.2 0.3 2.9 2 1 1 3 3 3 2 SPX domain Cupin_2 PF07883.11 PRP83792.1 - 1.6e-08 34.1 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 PRP83792.1 - 7.2e-06 25.6 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 PRP83792.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain EutQ PF06249.12 PRP83792.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ PRRSV_2b PF07069.11 PRP83792.1 - 0.11 13.0 0.3 0.2 12.2 0.3 1.4 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b PIP5K PF01504.18 PRP83793.1 - 6.3e-65 219.1 3.4 6.4e-65 219.1 0.4 2.3 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Frizzled PF01534.17 PRP83793.1 - 8.2e-07 28.4 19.0 9.8e-06 24.8 16.8 2.6 2 1 0 2 2 2 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.11 PRP83793.1 - 2.5e-05 23.6 18.4 0.0001 21.6 14.0 2.2 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 PRP83793.1 - 0.00025 20.4 11.4 0.00042 19.7 11.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 PRP83793.1 - 0.0014 18.6 0.3 0.0042 17.1 0.3 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF2208 PF09973.9 PRP83793.1 - 0.083 12.5 0.1 0.083 12.5 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DNA_pol_E_B PF04042.16 PRP83793.1 - 0.091 12.1 1.3 0.54 9.6 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B Peptidase_M56 PF05569.11 PRP83793.1 - 0.39 9.9 3.1 0.31 10.2 0.3 2.1 1 1 0 2 2 2 0 BlaR1 peptidase M56 WSC PF01822.19 PRP83795.1 - 8.1e-16 58.0 59.3 1.3e-07 31.7 9.8 12.6 8 3 3 11 11 11 6 WSC domain Syndecan PF01034.20 PRP83795.1 - 0.0086 16.0 0.1 0.13 12.2 0.1 3.2 1 0 0 1 1 1 1 Syndecan domain Insulin_TMD PF17870.1 PRP83795.1 - 0.17 12.0 3.9 0.39 10.8 3.9 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Ribosomal_L12 PF00542.19 PRP83796.1 - 1.2e-14 54.4 2.1 3.8e-14 52.8 0.7 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.19 PRP83796.1 - 3.8e-05 24.2 2.1 7.6e-05 23.2 2.1 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein PALP PF00291.25 PRP83797.1 - 6.3e-71 239.2 0.0 7.4e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NosD PF05048.13 PRP83797.1 - 0.21 10.8 1.6 1.5 8.0 0.8 2.1 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) C2 PF00168.30 PRP83798.1 - 3.2e-40 136.6 1.4 3.7e-21 75.3 0.2 2.4 2 0 0 2 2 2 2 C2 domain RasGAP PF00616.19 PRP83798.1 - 7.7e-27 94.4 0.0 1.3e-14 54.5 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PH PF00169.29 PRP83798.1 - 2.1e-10 41.0 0.2 6.1e-10 39.6 0.2 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP83798.1 - 0.012 16.0 0.0 0.047 14.1 0.0 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain Ig_mannosidase PF17753.1 PRP83799.1 - 0.087 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Ig-fold domain RibD_C PF01872.17 PRP83800.1 - 1.2e-40 139.5 0.4 2e-40 138.7 0.4 1.4 1 0 0 1 1 1 1 RibD C-terminal domain Lum_binding PF00677.17 PRP83800.1 - 2.5e-37 126.7 0.3 9.7e-22 76.8 0.0 2.8 2 0 0 2 2 2 2 Lumazine binding domain dCMP_cyt_deam_1 PF00383.23 PRP83800.1 - 6.8e-23 80.5 0.0 1.6e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PRP83800.1 - 1.9e-12 47.1 0.0 5.5e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 PRP83800.1 - 0.03 14.2 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 APOBEC-like N-terminal domain HGTP_anticodon PF03129.20 PRP83801.1 - 9.9e-19 67.3 0.1 4.6e-18 65.2 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 PRP83801.1 - 9.6e-09 35.5 0.0 2.6e-08 34.1 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) NYN PF01936.18 PRP83802.1 - 1.6e-29 103.3 0.0 9.2e-29 100.8 0.0 2.2 3 0 0 3 3 3 1 NYN domain OHA PF14418.6 PRP83802.1 - 0.00045 20.0 0.1 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 OST-HTH Associated domain DUF4350 PF14258.6 PRP83802.1 - 0.028 14.8 0.0 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) PIN7 PF18475.1 PRP83802.1 - 0.054 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 PIN domain Abhydrolase_3 PF07859.13 PRP83804.1 - 2.3e-26 93.0 0.0 2.8e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PRP83804.1 - 0.0036 16.2 0.0 0.0039 16.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase GYD PF08734.11 PRP83804.1 - 0.11 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 GYD domain Rap_GAP PF02145.15 PRP83806.1 - 1e-23 83.8 0.0 3e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP TFCD_C PF12612.8 PRP83806.1 - 0.0068 16.2 0.9 0.049 13.5 0.0 2.8 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal Pkinase_Tyr PF07714.17 PRP83808.1 - 1.2e-62 211.5 0.0 1.6e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83808.1 - 2.4e-48 164.8 0.0 3.5e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP83808.1 - 2.6e-13 49.9 0.0 5.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 PRP83808.1 - 0.00073 18.6 0.1 0.0085 15.1 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PRP83808.1 - 0.016 15.1 0.3 0.059 13.3 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cbl_N2 PF02761.14 PRP83808.1 - 0.046 14.4 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain ABC1 PF03109.16 PRP83808.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC1 family WhiA_N PF10298.9 PRP83809.1 - 0.021 14.8 0.1 0.058 13.5 0.1 1.7 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain MFS_3 PF05977.13 PRP83809.1 - 0.13 10.7 0.1 0.21 9.9 0.1 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Mce4_CUP1 PF11887.8 PRP83809.1 - 0.15 11.5 1.8 0.32 10.4 1.8 1.5 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative HALZ PF02183.18 PRP83809.1 - 4.5 7.6 24.8 0.82 9.9 1.0 5.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper PTS_2-RNA PF01885.16 PRP83810.1 - 8.1e-65 218.2 0.2 1.1e-64 217.8 0.2 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Yippee-Mis18 PF03226.14 PRP83810.1 - 2.6e-10 40.4 4.6 5.2e-10 39.5 4.6 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MH2 PF03166.14 PRP83810.1 - 0.045 14.0 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 MH2 domain ADH_zinc_N PF00107.26 PRP83811.1 - 1e-15 57.8 0.0 1.9e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP83811.1 - 3.3e-07 31.4 0.0 1e-06 29.8 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP83811.1 - 5.6e-07 29.4 0.1 1.2e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 PRP83811.1 - 0.018 14.9 0.1 0.05 13.5 0.1 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase FHA PF00498.26 PRP83812.1 - 8.3e-19 67.7 0.0 4.1e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 PRP83812.1 - 1.2e-08 35.1 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 PRP83812.1 - 0.00081 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF755 PF05501.11 PRP83812.1 - 0.012 15.9 13.9 0.029 14.7 13.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CDC45 PF02724.14 PRP83812.1 - 0.52 8.5 13.8 0.54 8.5 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Herpes_UL25 PF01499.16 PRP83812.1 - 0.7 8.4 2.4 0.93 7.9 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4746 PF15928.5 PRP83812.1 - 2.9 7.2 9.7 4.1 6.7 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_11 PF13086.6 PRP83812.1 - 4.7 6.9 9.0 6.3 6.5 9.0 1.4 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 PRP83812.1 - 9.3 4.9 10.7 12 4.5 10.7 1.1 1 0 0 1 1 1 0 Presenilin ABC1 PF03109.16 PRP83813.1 - 3.2e-31 108.0 0.3 5.4e-31 107.2 0.3 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PRP83813.1 - 0.00032 20.7 0.2 0.13 12.1 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 PRP83813.1 - 0.0035 16.8 0.0 0.0085 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain ArfGap PF01412.18 PRP83814.1 - 0.00016 21.7 0.0 0.00045 20.3 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SNARE_assoc PF09335.11 PRP83814.1 - 0.00028 21.3 0.7 0.7 10.4 0.0 2.7 2 0 0 2 2 2 2 SNARE associated Golgi protein YebO PF13974.6 PRP83814.1 - 0.00058 19.9 0.8 0.16 12.1 0.2 2.7 2 0 0 2 2 2 2 YebO-like protein DUF4448 PF14610.6 PRP83814.1 - 0.016 15.0 0.0 6.6 6.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4448) Epiglycanin_C PF14654.6 PRP83814.1 - 0.22 11.6 1.6 0.79 9.8 0.0 2.8 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region Peptidase_M24 PF00557.24 PRP83816.1 - 8e-57 192.3 0.1 1.2e-56 191.7 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 PRP83816.1 - 1.4e-23 83.0 0.0 3.2e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.18 PRP83816.1 - 0.039 14.6 0.0 0.079 13.6 0.0 1.5 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain PhoPQ_related PF10142.9 PRP83817.1 - 0.12 11.1 0.3 4.3 5.9 0.2 2.1 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein GATA PF00320.27 PRP83818.1 - 3.2e-12 45.8 4.8 6.7e-12 44.8 4.8 1.6 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 PRP83818.1 - 0.057 13.5 1.2 0.13 12.4 0.3 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Proteasom_PSMB PF10508.9 PRP83820.1 - 5.4e-55 186.8 0.0 6.6e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.14 PRP83820.1 - 4.5e-05 22.9 1.5 0.00029 20.2 0.3 2.5 2 1 1 3 3 3 1 V-ATPase subunit H Adaptin_N PF01602.20 PRP83820.1 - 0.0013 17.4 0.3 0.0021 16.7 0.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 PRP83820.1 - 0.0041 17.3 0.1 35 5.0 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 PRP83820.1 - 0.021 15.2 0.0 0.61 10.5 0.0 3.3 3 1 1 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 PRP83820.1 - 0.061 13.8 0.1 27 5.4 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.7 PRP83820.1 - 0.066 13.3 2.4 0.44 10.6 0.2 3.1 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 PRP83820.1 - 0.15 12.3 0.2 25 5.2 0.0 4.0 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 LRR_8 PF13855.6 PRP83821.1 - 4e-08 32.9 3.1 4e-08 32.9 3.1 2.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PRP83821.1 - 0.00026 21.3 1.4 0.00026 21.3 1.4 4.3 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PRP83821.1 - 0.0063 16.8 4.0 0.024 14.9 4.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain PAS_8 PF13188.7 PRP83821.1 - 0.048 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF4381 PF14316.6 PRP83821.1 - 0.089 13.0 0.1 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Zn_clus PF00172.18 PRP83821.1 - 0.18 12.0 2.4 0.4 10.9 2.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_1 PF00560.33 PRP83821.1 - 6.9 7.7 10.0 1.3e+02 3.8 0.5 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat PM0188 PF11477.8 PRP83822.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 Myosin_head PF00063.21 PRP83823.1 - 2.3e-236 786.2 0.7 3.6e-236 785.6 0.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 PRP83823.1 - 2.8e-34 118.4 0.4 4.8e-34 117.7 0.4 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Cas_APE2256 PF09651.10 PRP83823.1 - 0.019 14.9 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) AAA_22 PF13401.6 PRP83823.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain GCFC PF07842.12 PRP83823.1 - 0.16 11.6 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 GC-rich sequence DNA-binding factor-like protein NACHT PF05729.12 PRP83823.1 - 0.2 11.5 0.1 0.38 10.7 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Rad60-SLD PF11976.8 PRP83824.1 - 5.6e-24 83.8 0.7 8.8e-24 83.1 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PRP83824.1 - 8.5e-13 47.9 0.1 1.1e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family RhoGEF PF00621.20 PRP83825.1 - 3.3e-47 161.1 2.3 1.4e-46 159.0 2.3 2.2 1 0 0 1 1 1 1 RhoGEF domain DZR PF12773.7 PRP83825.1 - 7.3e-05 22.7 9.0 0.0061 16.5 1.3 2.4 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 PRP83825.1 - 0.01 16.5 1.9 0.01 16.5 1.9 4.5 3 1 0 3 3 3 0 zinc-ribbon family zf-ribbon_3 PF13248.6 PRP83825.1 - 0.07 12.6 6.5 0.52 9.8 2.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 PRP83825.1 - 0.28 11.1 6.1 2.6 8.1 0.3 2.7 2 0 0 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 PRP83825.1 - 0.33 10.7 9.7 3.6 7.4 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 PRP83825.1 - 0.69 10.1 4.7 5.2 7.3 1.6 2.9 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like C1_1 PF00130.22 PRP83825.1 - 2.4 8.1 7.9 11 6.1 1.1 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GFA PF04828.14 PRP83825.1 - 2.6 8.5 5.5 4.2 7.8 0.2 3.1 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Resolvase PF00239.21 PRP83826.1 - 1.3e-05 25.4 0.3 0.025 14.7 0.0 2.5 2 0 0 2 2 2 2 Resolvase, N terminal domain RINT1_TIP1 PF04437.13 PRP83826.1 - 0.034 13.0 1.5 0.051 12.5 0.2 1.9 2 0 0 2 2 2 0 RINT-1 / TIP-1 family MatP PF06303.12 PRP83826.1 - 0.096 13.3 0.6 0.31 11.6 0.6 1.8 1 0 0 1 1 1 0 MatP N-terminal domain Rotamase PF00639.21 PRP83826.1 - 0.97 10.4 4.0 0.73 10.8 0.3 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain Corona_nucleoca PF00937.18 PRP83826.1 - 1.6 7.7 10.1 2.3 7.2 4.4 2.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein GTP-bdg_M PF16360.5 PRP83827.1 - 1.7e-20 73.4 5.3 1.7e-20 73.4 5.3 1.9 2 0 0 2 2 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 PRP83827.1 - 3.2e-19 69.4 0.0 9.9e-19 67.8 0.0 1.9 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal MMR_HSR1 PF01926.23 PRP83827.1 - 1.7e-11 44.2 0.0 6.8e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP83827.1 - 1.8e-06 27.5 0.2 5.1e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP83827.1 - 6.4e-06 26.2 0.1 0.17 11.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 PRP83827.1 - 0.0004 20.3 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 PRP83827.1 - 0.0012 18.9 0.1 0.0076 16.3 0.0 2.4 1 1 1 2 2 2 1 Dynamin family MeaB PF03308.16 PRP83827.1 - 0.0064 15.5 0.0 0.17 10.8 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 PRP83827.1 - 0.013 14.9 0.0 0.069 12.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein cobW PF02492.19 PRP83827.1 - 0.025 14.2 0.1 4.4 6.9 0.0 2.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrmO PF01980.16 PRP83827.1 - 0.033 14.4 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 tRNA-methyltransferase O GTP_EFTU PF00009.27 PRP83827.1 - 0.051 13.1 0.0 11 5.5 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 PRP83827.1 - 0.083 13.4 0.0 2.7 8.5 0.0 3.1 3 0 0 3 3 3 0 ABC transporter Roc PF08477.13 PRP83827.1 - 0.15 12.2 0.1 1.5 9.1 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PgaPase_1 PF06162.12 PRP83829.1 - 0.026 14.3 0.2 0.045 13.5 0.2 1.4 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 IBR PF01485.21 PRP83830.1 - 1.7e-08 34.6 37.2 1.9e-08 34.4 8.3 3.7 3 2 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PRP83830.1 - 5.5e-06 26.6 4.8 5.5e-06 26.6 4.8 4.0 4 0 0 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 PRP83830.1 - 5.9e-06 26.2 3.5 5.9e-06 26.2 3.5 3.8 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP83830.1 - 5.1e-05 23.0 4.5 5.1e-05 23.0 4.5 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP83830.1 - 0.0002 21.2 4.2 0.0002 21.2 4.2 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP83830.1 - 0.012 15.7 2.7 0.012 15.7 2.7 4.2 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PRP83830.1 - 0.027 14.3 2.4 0.027 14.3 2.4 4.0 3 1 0 3 3 3 0 zf-RING of BARD1-type protein TRAF6_Z2 PF18048.1 PRP83830.1 - 0.25 11.5 12.2 0.68 10.1 5.2 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-RING_11 PF17123.5 PRP83830.1 - 9.5 6.1 15.3 0.19 11.5 6.5 2.8 2 0 0 2 2 2 0 RING-like zinc finger zinc_ribbon_2 PF13240.6 PRP83831.1 - 0.0037 16.9 3.7 0.0037 16.9 3.7 2.1 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 PRP83831.1 - 0.016 15.2 5.4 0.016 15.2 5.4 2.1 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 PRP83831.1 - 0.095 13.5 1.9 0.39 11.5 1.9 2.1 1 0 0 1 1 1 0 zinc-ribbon family zf-ribbon_3 PF13248.6 PRP83831.1 - 3.8 7.1 9.3 5.6 6.5 5.8 2.7 2 1 1 3 3 3 0 zinc-ribbon domain Glyco_hydro_26 PF02156.15 PRP83833.1 - 0.074 12.5 0.0 0.71 9.3 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 26 HA2 PF04408.23 PRP83835.1 - 0.064 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Helicase associated domain (HA2) PAX PF00292.18 PRP83835.1 - 0.075 13.0 0.0 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 'Paired box' domain WD40 PF00400.32 PRP83836.1 - 2.2e-20 72.6 15.2 4.2e-05 24.2 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat SAP30_Sin3_bdg PF13867.6 PRP83836.1 - 2.1e-12 47.2 0.3 6.7e-12 45.6 0.3 1.9 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 ANAPC4_WD40 PF12894.7 PRP83836.1 - 4.5e-08 33.3 0.0 0.00026 21.2 0.0 4.3 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP83836.1 - 0.0032 16.9 0.5 0.03 13.7 0.4 2.6 1 1 0 1 1 1 1 WD40-like domain PQQ_2 PF13360.6 PRP83836.1 - 0.0079 15.8 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 PQQ-like domain DUF2935 PF11155.8 PRP83836.1 - 0.88 9.9 17.4 3.8 7.8 6.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) IMS PF00817.20 PRP83836.1 - 0.9 9.5 3.4 0.74 9.8 0.7 2.3 2 0 0 2 2 2 0 impB/mucB/samB family Alg6_Alg8 PF03155.15 PRP83837.1 - 5.3e-127 424.7 26.2 7.3e-127 424.3 26.2 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WD40 PF00400.32 PRP83837.1 - 1.6e-07 31.9 16.5 8.8e-05 23.2 1.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat GT87 PF09594.10 PRP83837.1 - 0.00017 21.4 4.0 0.00017 21.4 4.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase family 87 WD40_like PF17005.5 PRP83837.1 - 0.025 13.9 0.1 0.13 11.6 0.0 2.1 3 0 0 3 3 3 0 WD40-like domain Peptidase_M3 PF01432.20 PRP83838.1 - 5.5e-140 467.7 0.2 7.8e-140 467.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 Homeodomain PF00046.29 PRP83838.1 - 1.1e-06 28.4 7.9 2.9e-06 27.0 1.0 3.3 3 0 0 3 3 3 1 Homeodomain Ephrin_rec_like PF07699.13 PRP83838.1 - 1.9e-06 27.5 24.9 4.6e-05 23.1 10.7 5.9 1 1 4 5 5 5 3 Putative ephrin-receptor like Homeobox_KN PF05920.11 PRP83838.1 - 0.0026 17.6 0.2 0.008 16.1 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain LapA_dom PF06305.11 PRP83838.1 - 0.27 11.1 1.1 18 5.2 0.1 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain VSP PF03302.13 PRP83838.1 - 1.2 8.0 39.8 59 2.3 39.0 2.2 1 1 1 2 2 2 0 Giardia variant-specific surface protein RTA1 PF04479.13 PRP83842.1 - 2.7e-45 154.5 2.1 2.7e-45 154.5 2.1 1.6 2 0 0 2 2 2 1 RTA1 like protein SieB PF14163.6 PRP83842.1 - 2.6 7.5 5.5 1.8 8.0 0.1 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B NCBP3 PF10309.9 PRP83843.1 - 2.8e-06 27.1 0.0 5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RRM_3 PF08777.11 PRP83843.1 - 0.095 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif RasGEF PF00617.19 PRP83846.1 - 1.2e-37 129.8 0.3 2.8e-37 128.6 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain HEPN-like_int PF18867.1 PRP83846.1 - 0.025 14.4 0.1 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 HEPN-like integron domain RasGEF_N PF00618.20 PRP83846.1 - 0.099 12.9 0.3 1.2 9.4 0.3 2.5 1 1 0 1 1 1 0 RasGEF N-terminal motif PH PF00169.29 PRP83847.1 - 2.8e-16 59.9 0.1 9.6e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 PH domain SNARE PF05739.19 PRP83847.1 - 3.5e-08 33.3 0.4 8.1e-08 32.1 0.4 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 PRP83847.1 - 4e-06 26.6 6.9 2e-05 24.4 6.7 2.4 1 1 1 2 2 2 1 Syntaxin NPV_P10 PF05531.12 PRP83847.1 - 0.011 16.2 4.2 0.16 12.4 1.1 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 PRP83847.1 - 0.07 13.2 7.3 0.9 9.6 0.4 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RasGAP_C PF03836.15 PRP83847.1 - 0.16 12.1 8.4 0.15 12.2 5.2 2.5 2 0 0 2 2 2 0 RasGAP C-terminus SKA2 PF16740.5 PRP83847.1 - 0.19 11.6 9.2 1 9.2 0.5 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TSC22 PF01166.18 PRP83847.1 - 0.36 11.2 2.3 0.5 10.7 0.6 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Jnk-SapK_ap_N PF09744.9 PRP83847.1 - 0.56 10.4 8.3 3.4 7.9 5.7 2.7 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Syntaxin_2 PF14523.6 PRP83847.1 - 0.58 10.6 13.5 1.6 9.2 0.1 3.1 2 1 0 2 2 2 0 Syntaxin-like protein PH_11 PF15413.6 PRP83847.1 - 0.6 10.6 0.0 0.6 10.6 0.0 2.6 3 0 0 3 3 3 0 Pleckstrin homology domain DUF948 PF06103.11 PRP83847.1 - 1.5 9.1 3.2 42 4.5 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FlxA PF14282.6 PRP83847.1 - 9.2 6.3 18.4 0.29 11.1 10.3 2.8 2 1 0 2 2 2 0 FlxA-like protein Pkinase PF00069.25 PRP83848.1 - 6.8e-71 238.7 0.2 6.8e-71 238.7 0.2 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83848.1 - 2.4e-52 177.8 0.2 2.4e-52 177.8 0.2 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 PRP83848.1 - 2.9e-06 27.5 0.1 2.6e-05 24.5 0.0 3.0 2 0 0 2 2 2 1 P21-Rho-binding domain Seadorna_VP7 PF07387.11 PRP83848.1 - 0.051 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 RhoGEF PF00621.20 PRP83849.1 - 1.2e-47 162.5 0.5 3.3e-47 161.1 0.5 1.8 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 PRP83849.1 - 2.3e-08 33.8 0.6 6.8e-08 32.3 0.6 1.8 1 0 0 1 1 1 1 PB1 domain DX PF01666.17 PRP83849.1 - 0.07 13.6 0.5 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 DX module G10 PF01125.17 PRP83849.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 G10 protein G8 PF10162.9 PRP83850.1 - 7.5e-14 51.9 0.1 2.6e-13 50.1 0.1 1.9 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP83850.1 - 0.026 14.4 11.3 0.015 15.2 5.6 3.5 2 1 1 3 3 3 0 Right handed beta helix region WD40 PF00400.32 PRP83851.1 - 7.6e-40 134.2 23.9 8.6e-05 23.2 0.2 12.0 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP83851.1 - 1.1e-05 25.6 7.1 5.5 7.4 0.2 7.2 4 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP83851.1 - 0.0034 16.7 3.4 0.64 9.3 0.0 3.9 3 1 0 4 4 4 1 WD40-like domain Kelch_6 PF13964.6 PRP83851.1 - 0.13 12.6 0.1 11 6.5 0.1 3.5 2 0 0 2 2 2 0 Kelch motif HAUS2 PF15003.6 PRP83852.1 - 3.5e-13 49.7 5.3 4.1e-13 49.5 5.3 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 ABC_tran_CTD PF16326.5 PRP83852.1 - 0.00026 21.2 6.2 0.025 14.8 4.1 2.9 1 1 2 3 3 3 1 ABC transporter C-terminal domain CCDC-167 PF15188.6 PRP83852.1 - 0.026 14.9 4.5 1.2 9.5 1.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FH2 PF02181.23 PRP83852.1 - 0.051 12.7 2.0 0.3 10.2 0.4 2.0 2 0 0 2 2 2 0 Formin Homology 2 Domain TMF_DNA_bd PF12329.8 PRP83852.1 - 0.058 13.4 2.1 0.14 12.2 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.12 PRP83852.1 - 0.067 13.7 4.3 0.26 11.8 0.2 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 PRP83852.1 - 0.48 10.5 4.7 2.1 8.4 0.2 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_M1 PF01433.20 PRP83853.1 - 9.9e-71 237.8 0.5 1.9e-70 236.8 0.5 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 PRP83853.1 - 1.9e-45 155.8 1.1 1.9e-45 155.8 1.1 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PRP83853.1 - 4.4e-30 105.2 0.1 1.5e-29 103.5 0.1 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Oxidored_FMN PF00724.20 PRP83854.1 - 2.4e-79 267.1 0.0 2.8e-79 266.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1729 PF08354.10 PRP83854.1 - 0.074 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) ThiF PF00899.21 PRP83857.1 - 2.1e-70 236.9 0.0 3.8e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 PRP83857.1 - 5.4e-20 71.8 0.4 1.6e-19 70.3 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 PRP83857.1 - 6.4e-10 39.4 9.3 6e-07 29.6 0.2 2.6 2 1 0 3 3 3 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 PRP83857.1 - 0.00019 21.5 0.3 0.02 15.0 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 PRP83857.1 - 0.027 14.9 0.0 0.095 13.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Plasmod_dom_1 PF09715.10 PRP83857.1 - 0.034 14.2 0.1 0.084 12.9 0.1 1.7 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Sacchrp_dh_NADP PF03435.18 PRP83857.1 - 0.035 14.4 0.8 0.13 12.5 0.1 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Sortilin-Vps10 PF15902.5 PRP83859.1 - 2.2e-60 204.7 0.4 3.6e-60 204.0 0.0 1.4 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, GATase PF00117.28 PRP83859.1 - 1e-34 120.0 0.0 2.4e-34 118.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Sortilin_C PF15901.5 PRP83859.1 - 4.4e-30 105.3 5.2 7e-30 104.6 5.2 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal GMP_synt_C PF00958.22 PRP83859.1 - 9.4e-17 60.9 0.0 1.5e-09 37.8 0.0 3.3 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 PRP83859.1 - 3.8e-13 49.7 0.0 8.4e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 PRP83859.1 - 2e-10 40.2 0.2 1.9e-06 27.2 0.1 2.3 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 PRP83859.1 - 1.5e-05 24.6 0.0 0.00034 20.2 0.0 2.4 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 PRP83859.1 - 0.019 14.2 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 PRP83859.1 - 0.065 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 PRP83859.1 - 0.075 11.8 0.0 0.45 9.2 0.0 2.2 3 0 0 3 3 3 0 tRNA methyl transferase BNR PF02012.20 PRP83859.1 - 0.28 11.3 4.2 3 8.2 0.1 3.8 4 0 0 4 4 2 0 BNR/Asp-box repeat Carboxyl_trans PF01039.22 PRP83861.1 - 1e-185 618.1 0.0 1.7e-185 617.4 0.0 1.3 1 1 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 PRP83861.1 - 0.003 17.1 0.0 0.013 15.0 0.0 2.0 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) DUF3381 PF11861.8 PRP83861.1 - 2.2 8.1 6.7 0.12 12.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Kinesin PF00225.23 PRP83863.1 - 3.4e-100 335.2 0.3 6.3e-100 334.3 0.3 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PRP83863.1 - 1.2e-22 80.5 0.0 2.7e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HIGH_NTase1_ass PF16581.5 PRP83863.1 - 0.018 15.0 0.2 0.042 13.8 0.2 1.5 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Sfi1_C PF10638.9 PRP83863.1 - 0.18 12.6 2.7 0.35 11.6 0.0 2.8 2 1 1 3 3 3 0 Spindle body associated protein C-terminus DUF4769 PF15992.5 PRP83863.1 - 0.92 9.3 5.6 0.37 10.6 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4769) DUF913 PF06025.12 PRP83863.1 - 1.2 8.1 11.4 0.4 9.6 1.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FlaC_arch PF05377.11 PRP83864.1 - 0.31 11.4 22.0 0.36 11.3 1.2 5.9 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) HALZ PF02183.18 PRP83864.1 - 1.5 9.1 11.8 0.9 9.8 0.3 4.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper Homeodomain PF00046.29 PRP83865.1 - 3.2e-12 46.1 4.4 4.3e-12 45.7 2.2 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP83865.1 - 1.4e-05 24.9 1.7 5.7e-05 22.9 1.7 2.1 1 0 0 1 1 1 1 Homeobox KN domain Glyco_hydro_16 PF00722.21 PRP83865.1 - 3.4e-05 23.4 0.0 6.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3147 PF11345.8 PRP83866.1 - 0.0026 18.1 1.1 0.0026 18.1 1.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3147) OSTbeta PF15048.6 PRP83866.1 - 0.02 15.0 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein V_ATPase_I PF01496.19 PRP83866.1 - 0.11 10.4 0.0 0.16 9.9 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5367 PF17329.2 PRP83866.1 - 0.17 12.0 14.1 0.14 12.3 2.4 3.6 4 1 0 4 4 4 0 Family of unknown function (DUF5367) Homeodomain PF00046.29 PRP83867.1 - 7.7e-18 64.1 3.7 1.2e-17 63.4 3.7 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP83867.1 - 3.1e-05 23.8 0.7 3.1e-05 23.8 0.7 2.3 2 1 2 4 4 4 1 Homeobox KN domain Zip PF02535.22 PRP83868.1 - 2.7e-44 151.8 3.2 3.6e-44 151.4 3.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter YIF1 PF03878.15 PRP83868.1 - 0.00022 20.8 0.5 0.00037 20.1 0.5 1.3 1 0 0 1 1 1 1 YIF1 G8 PF10162.9 PRP83870.1 - 1.9e-19 69.9 0.8 5.1e-19 68.6 0.8 1.7 1 0 0 1 1 1 1 G8 domain SH3_2 PF07653.17 PRP83872.1 - 8.2e-24 83.1 0.1 1.2e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 PRP83872.1 - 5.7e-20 70.9 0.5 8.9e-09 35.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PRP83872.1 - 1.4e-19 69.4 0.7 5.1e-10 38.8 0.1 2.6 2 0 0 2 2 2 2 SH3 domain hSH3 PF14603.6 PRP83872.1 - 0.0013 19.1 0.4 0.012 16.1 0.0 2.7 3 0 0 3 3 2 1 Helically-extended SH3 domain zf-C4H2 PF10146.9 PRP83872.1 - 0.0018 18.7 12.1 0.0039 17.5 12.1 1.6 1 0 0 1 1 1 1 Zinc finger-containing protein ADIP PF11559.8 PRP83872.1 - 0.0077 16.3 20.4 0.0077 16.3 20.4 2.4 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding LPP PF04728.13 PRP83872.1 - 0.12 12.8 5.6 0.07 13.5 1.8 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Filament PF00038.21 PRP83872.1 - 0.13 11.8 25.9 0.085 12.4 11.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein KASH_CCD PF14662.6 PRP83872.1 - 0.13 12.0 26.9 0.23 11.3 26.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ACR_tran PF00873.19 PRP83872.1 - 0.19 9.3 6.5 0.28 8.8 6.5 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family GAS PF13851.6 PRP83872.1 - 0.49 9.7 28.6 1.7 8.0 3.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 PRP83872.1 - 0.73 9.9 22.3 1.3 9.0 22.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 PRP83872.1 - 1.8 8.7 22.5 0.15 12.2 1.8 3.7 2 1 0 3 3 3 0 bZIP transcription factor Flagellin_C PF00700.21 PRP83872.1 - 2 8.8 14.1 0.99 9.8 4.2 2.5 1 1 1 2 2 2 0 Bacterial flagellin C-terminal helical region SlyX PF04102.12 PRP83872.1 - 2 9.1 24.0 4.9 7.9 5.6 3.8 1 1 2 3 3 3 0 SlyX PI_PP_I PF18363.1 PRP83872.1 - 2.5 8.3 5.6 3.7 7.8 1.9 2.4 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain FapA PF03961.13 PRP83872.1 - 3.1 6.3 13.5 5.3 5.5 13.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mod_r PF07200.13 PRP83872.1 - 3.4 7.8 25.2 1.3 9.1 13.9 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cnn_1N PF07989.11 PRP83872.1 - 4.3 7.5 23.3 0.16 12.2 6.1 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 FOXP-CC PF16159.5 PRP83872.1 - 6.4 7.5 9.2 1.3 9.7 1.4 2.9 1 1 1 2 2 2 0 FOXP coiled-coil domain Ank_5 PF13857.6 PRP83874.1 - 4.2e-26 90.7 5.4 2.4e-06 27.7 0.2 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP83874.1 - 3e-25 88.6 1.4 4.4e-11 43.2 0.0 3.4 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP83874.1 - 6.1e-22 75.3 1.2 0.0024 18.2 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 PRP83874.1 - 2.6e-20 71.9 2.3 1.8e-05 24.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PRP83874.1 - 1.2e-19 70.4 1.0 6.5e-07 29.8 0.0 4.4 1 1 2 4 4 4 4 Ankyrin repeats (many copies) CAF-1_p150 PF11600.8 PRP83874.1 - 0.014 15.1 5.4 0.021 14.5 5.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal tRNA-synt_1c_C PF03950.18 PRP83874.1 - 0.066 13.1 0.0 0.7 9.7 0.0 2.2 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), anti-codon binding domain RCC1 PF00415.18 PRP83876.1 - 9e-34 115.9 11.4 2.2e-09 37.8 0.2 8.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat TLD PF07534.16 PRP83876.1 - 7.2e-30 104.0 0.8 2.4e-29 102.3 0.8 2.0 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 PRP83876.1 - 3.3e-17 62.8 3.3 7.2e-17 61.8 3.3 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RCC1_2 PF13540.6 PRP83876.1 - 1.5e-15 56.6 15.9 5.4e-09 35.6 0.9 5.4 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat C1_1 PF00130.22 PRP83876.1 - 0.0026 17.6 6.1 0.0055 16.6 6.1 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 PRP83876.1 - 0.0037 17.5 2.5 0.013 15.8 2.5 2.0 1 0 0 1 1 1 1 C1 domain Homeodomain PF00046.29 PRP83877.1 - 7e-06 25.8 0.2 9.4e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP83877.1 - 0.081 12.8 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Homeobox KN domain AAA PF00004.29 PRP83878.1 - 1.1e-87 291.2 0.0 9.3e-43 145.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP83878.1 - 1.1e-22 79.5 0.3 5.4e-10 38.9 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 PRP83878.1 - 2.8e-13 49.9 0.0 5.1e-06 26.3 0.0 3.0 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PRP83878.1 - 1.4e-10 41.3 0.5 0.00038 20.5 0.0 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP83878.1 - 1.6e-10 41.7 0.0 0.0005 20.5 0.0 4.2 3 2 1 4 4 4 2 AAA ATPase domain AAA_2 PF07724.14 PRP83878.1 - 1.4e-07 31.8 0.0 0.024 14.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PRP83878.1 - 8.2e-07 28.5 0.0 0.01 15.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_25 PF13481.6 PRP83878.1 - 1.5e-06 27.9 2.3 0.85 9.2 0.0 4.3 2 2 1 4 4 4 2 AAA domain CDC48_N PF02359.18 PRP83878.1 - 5.4e-06 26.5 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RNA_helicase PF00910.22 PRP83878.1 - 5.6e-06 26.7 0.0 0.079 13.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_22 PF13401.6 PRP83878.1 - 6.9e-06 26.4 1.5 0.055 13.7 0.0 4.1 3 2 2 5 5 5 1 AAA domain AAA_33 PF13671.6 PRP83878.1 - 9.4e-06 25.8 0.0 0.078 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 PRP83878.1 - 9.9e-06 25.1 0.4 0.079 12.3 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PRP83878.1 - 1.8e-05 24.8 0.0 0.054 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 PRP83878.1 - 4.8e-05 23.2 0.4 0.35 10.6 0.1 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein Rad17 PF03215.15 PRP83878.1 - 0.00019 21.4 0.0 0.012 15.6 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 PRP83878.1 - 0.00028 21.2 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PRP83878.1 - 0.00091 19.8 0.0 0.09 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PRP83878.1 - 0.00099 18.7 0.0 0.47 9.9 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_3 PF07726.11 PRP83878.1 - 0.00099 19.0 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 PRP83878.1 - 0.001 19.1 0.0 0.52 10.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 PRP83878.1 - 0.0014 18.4 0.9 1.3 8.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 PRP83878.1 - 0.0014 18.3 0.0 0.47 10.1 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 PRP83878.1 - 0.0036 17.4 0.0 2.5 8.2 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_11 PF13086.6 PRP83878.1 - 0.009 15.8 0.0 0.61 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PRP83878.1 - 0.0094 15.7 0.1 0.66 9.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 PRP83878.1 - 0.0098 15.3 0.0 1.6 8.0 0.0 2.6 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.17 PRP83878.1 - 0.01 14.9 0.1 0.26 10.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.25 PRP83878.1 - 0.017 14.7 0.0 0.1 12.3 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.16 PRP83878.1 - 0.02 14.4 0.6 0.44 10.0 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 PRP83878.1 - 0.021 15.2 0.7 0.65 10.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 PRP83878.1 - 0.058 13.9 0.1 3.7 8.1 0.0 2.9 3 0 0 3 3 2 0 ABC transporter Zeta_toxin PF06414.12 PRP83878.1 - 0.058 12.7 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 PRP83878.1 - 0.061 13.2 0.0 4.4 7.1 0.0 3.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 PRP83878.1 - 0.11 12.9 0.1 9.1 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 PRP83878.1 - 0.15 11.2 0.0 8.6 5.4 0.0 2.7 3 1 0 3 3 2 0 Protein of unknown function (DUF815) UBA_3 PF09288.10 PRP83879.1 - 0.092 12.6 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain LAGLIDADG_3 PF14528.6 PRP83879.1 - 0.16 12.3 0.0 0.29 11.5 0.0 1.7 2 1 0 2 2 2 0 LAGLIDADG-like domain Chitin_synth_1N PF08407.11 PRP83880.1 - 0.048 13.6 0.5 0.71 9.9 0.0 2.4 2 0 0 2 2 2 0 Chitin synthase N-terminal Nop16 PF09420.10 PRP83881.1 - 2.3e-11 44.1 4.6 1.6e-05 25.1 0.0 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 LIM PF00412.22 PRP83882.1 - 1e-15 57.7 10.0 8.3e-10 38.7 2.1 3.4 3 0 0 3 3 3 2 LIM domain RNA_POL_M_15KD PF02150.16 PRP83882.1 - 0.0017 18.2 0.7 0.0017 18.2 0.7 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TNFR_c6 PF00020.18 PRP83882.1 - 0.16 12.4 5.4 5.2 7.5 0.5 2.9 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region DZR PF12773.7 PRP83882.1 - 1.1 9.3 7.9 3 8.0 0.8 2.7 2 0 0 2 2 2 0 Double zinc ribbon SPRY PF00622.28 PRP83883.1 - 6.9e-10 39.1 0.1 1.6e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 PRP83883.1 - 5.9e-05 22.9 2.1 9.6e-05 22.2 0.3 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 PRP83883.1 - 0.0015 18.4 1.8 0.0029 17.4 0.1 2.4 3 0 0 3 3 3 1 F-box domain Neuralized PF07177.12 PRP83883.1 - 0.017 15.1 0.1 0.044 13.8 0.1 1.7 1 1 0 1 1 1 0 Neuralized G8 PF10162.9 PRP83884.1 - 3.4e-21 75.6 0.7 9.9e-21 74.1 0.7 1.9 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP83884.1 - 2.2 8.1 7.6 19 5.1 4.8 3.6 1 1 1 2 2 2 0 Right handed beta helix region LRR_6 PF13516.6 PRP83888.1 - 0.0092 16.0 0.1 0.039 14.0 0.0 2.0 2 0 0 2 2 2 1 Leucine Rich repeat WD40 PF00400.32 PRP83889.1 - 3.7e-29 100.4 23.2 4e-06 27.5 1.0 8.2 8 1 1 9 9 8 6 WD domain, G-beta repeat Hira PF07569.11 PRP83889.1 - 5.7e-24 85.1 3.5 1e-13 51.6 1.2 3.1 2 1 1 3 3 3 2 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 PRP83889.1 - 1.6e-17 63.6 0.1 9.9e-05 22.6 0.1 6.6 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP83889.1 - 2.3e-07 30.9 0.2 0.55 10.1 0.0 4.1 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PRP83889.1 - 0.00043 19.7 0.0 0.48 9.7 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain PD40 PF07676.12 PRP83889.1 - 0.0013 18.6 3.1 1.2 9.2 0.1 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 PRP83889.1 - 0.018 14.0 0.8 0.33 9.9 0.0 2.9 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 PRP83889.1 - 0.037 13.9 0.3 0.16 11.8 0.3 2.3 1 0 0 1 1 1 0 HIRA B motif DPPIV_N PF00930.21 PRP83889.1 - 0.051 12.3 0.8 6.5 5.4 0.0 4.0 4 1 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Uteroglobin PF01099.17 PRP83889.1 - 0.36 11.2 2.2 0.28 11.5 0.1 1.9 2 0 0 2 2 2 0 Uteroglobin family Nucleo_P87 PF07267.11 PRP83889.1 - 0.56 9.0 14.0 0.97 8.2 14.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Vfa1 PF08432.10 PRP83889.1 - 1.3 9.3 14.4 0.4 11.0 10.0 2.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 SWI-SNF_Ssr4 PF08549.10 PRP83889.1 - 1.9 7.0 11.0 2.8 6.5 11.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF1764 PF08576.10 PRP83890.1 - 8.5e-17 61.9 16.7 1.1e-15 58.4 16.7 2.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) ORC6 PF05460.13 PRP83890.1 - 0.3 10.3 9.7 0.34 10.1 9.7 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Hamartin PF04388.12 PRP83890.1 - 1.3 7.6 5.5 1.3 7.6 5.5 1.0 1 0 0 1 1 1 0 Hamartin protein Cation_efflux PF01545.21 PRP83891.1 - 2.8e-46 157.8 4.9 4.5e-46 157.1 4.9 1.3 1 0 0 1 1 1 1 Cation efflux family Glyco_hydro_28 PF00295.17 PRP83891.1 - 5e-24 85.0 0.7 9e-24 84.1 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 LRR_9 PF14580.6 PRP83891.1 - 3.2e-18 65.8 0.2 8.8e-17 61.1 0.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 PRP83891.1 - 9.7e-17 60.8 13.1 0.0001 22.6 0.2 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) ZT_dimer PF16916.5 PRP83891.1 - 2.1e-07 31.0 0.2 4.7e-07 29.8 0.2 1.6 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter LRR_8 PF13855.6 PRP83891.1 - 9.5e-06 25.3 12.7 2.4e-05 24.0 2.3 3.5 1 1 3 4 4 4 2 Leucine rich repeat Pectate_lyase_3 PF12708.7 PRP83891.1 - 0.00012 22.0 0.1 0.00012 22.0 0.1 2.8 2 1 0 2 2 2 1 Pectate lyase superfamily protein LRR_6 PF13516.6 PRP83891.1 - 1.3 9.3 6.9 4.9 7.5 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Cys_Met_Meta_PP PF01053.20 PRP83892.1 - 2.1e-55 187.8 0.0 6.7e-55 186.2 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PRP83892.1 - 0.0092 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 PRP83892.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Myotub-related PF06602.14 PRP83893.1 - 0.069 12.1 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.17 PRP83894.1 - 2.4e-70 236.8 0.0 3.3e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83894.1 - 3.9e-52 177.2 0.0 5.7e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP83894.1 - 1.2e-06 28.1 0.2 2e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP83894.1 - 0.0095 15.6 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP83894.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TMEM154 PF15102.6 PRP83894.1 - 0.023 14.6 12.1 0.14 12.0 0.0 2.6 2 0 0 2 2 2 0 TMEM154 protein family stn_TNFRSF12A PF12191.8 PRP83894.1 - 0.052 13.8 0.2 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Pkinase_fungal PF17667.1 PRP83894.1 - 0.15 10.8 0.6 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 PRP83894.1 - 0.16 11.9 0.1 16 5.3 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family MscL PF01741.18 PRP83894.1 - 0.17 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Apc15p PF05841.11 PRP83894.1 - 0.31 11.9 1.5 0.51 11.2 0.3 2.0 2 0 0 2 2 1 0 Apc15p protein Alpha_GJ PF03229.13 PRP83894.1 - 2.9 8.5 13.8 3.1 8.3 0.0 2.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J Alpha-amylase PF00128.24 PRP83896.1 - 3.6e-111 372.0 1.4 6.6e-111 371.1 0.5 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 PRP83896.1 - 9.9e-08 32.0 0.1 2.1e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Cyc-maltodext_C PF10438.9 PRP83896.1 - 0.00085 19.4 0.1 0.024 14.7 0.0 2.5 2 0 0 2 2 2 1 Cyclo-malto-dextrinase C-terminal domain DUF3459 PF11941.8 PRP83896.1 - 0.0012 19.2 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.6 PRP83896.1 - 0.0097 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Tegument_dsDNA PF12818.7 PRP83896.1 - 0.18 10.9 0.0 0.41 9.7 0.0 1.5 2 0 0 2 2 2 0 dsDNA viral tegument protein HTH_9 PF08221.11 PRP83897.1 - 2.4e-08 33.9 0.0 8.1e-07 29.0 0.0 3.0 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 PRP83897.1 - 1e-07 32.0 0.9 2.1e-07 31.0 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 Glyco_trans_1_4 PF13692.6 PRP83897.1 - 0.062 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 dUTPase_2 PF08761.11 PRP83898.1 - 0.086 13.0 0.1 0.37 11.0 0.1 1.9 2 0 0 2 2 2 0 dUTPase Lactamase_B_2 PF12706.7 PRP83899.1 - 7.4e-42 143.2 0.0 1.2e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PRP83899.1 - 4.4e-14 52.7 0.0 5.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP83899.1 - 0.0041 17.2 3.3 0.19 11.7 2.5 2.8 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily PPR_2 PF13041.6 PRP83901.1 - 4.1e-38 129.3 4.0 4.4e-09 36.4 0.1 6.0 3 2 3 6 6 6 5 PPR repeat family PPR_3 PF13812.6 PRP83901.1 - 3.3e-35 120.0 6.3 3.8e-13 49.3 0.0 5.3 3 2 2 5 5 5 5 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP83901.1 - 1.9e-17 63.3 0.2 1.3e-05 24.7 0.1 3.3 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PRP83901.1 - 2e-16 59.0 12.2 1.8e-05 24.6 0.1 8.2 9 0 0 9 9 9 4 PPR repeat PPR_1 PF12854.7 PRP83901.1 - 7.6e-13 47.9 11.1 0.0032 17.1 0.1 8.1 8 0 0 8 8 8 4 PPR repeat Exog_C PF18026.1 PRP83901.1 - 0.0015 18.5 0.0 0.41 10.7 0.0 3.1 2 0 0 2 2 2 1 Endo/exonuclease (EXOG) C-terminal domain Mad3_BUB1_I_2 PF17014.5 PRP83901.1 - 0.0046 17.1 0.9 0.06 13.5 0.1 2.5 2 1 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Pdase_M17_N2 PF18295.1 PRP83901.1 - 0.017 15.4 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 DUF5617 PF18493.1 PRP83901.1 - 0.019 15.0 0.2 3.4 7.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5617) BKACE PF05853.12 PRP83901.1 - 0.054 12.8 0.4 7.8 5.7 0.1 3.3 1 1 2 3 3 3 0 beta-keto acid cleavage enzyme DUF4265 PF14085.6 PRP83901.1 - 0.06 13.3 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) RraB PF06877.11 PRP83901.1 - 0.063 14.0 0.4 16 6.3 0.0 3.3 1 1 2 3 3 3 0 Regulator of ribonuclease activity B DUF1018 PF06252.12 PRP83901.1 - 0.069 14.1 0.0 1.2 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) DUF4248 PF14053.6 PRP83901.1 - 0.12 12.4 0.3 2.1 8.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Clathrin PF00637.20 PRP83901.1 - 0.45 10.4 7.3 13 5.7 0.1 4.0 3 2 2 5 5 5 0 Region in Clathrin and VPS DUF4298 PF14131.6 PRP83901.1 - 0.55 10.2 3.5 0.97 9.4 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) ParBc PF02195.18 PRP83901.1 - 0.79 10.1 3.0 30 5.0 0.1 3.6 3 1 1 4 4 4 0 ParB-like nuclease domain Clathrin_lg_ch PF01086.17 PRP83902.1 - 1.5e-25 90.6 2.7 1.7e-25 90.4 2.7 1.2 1 0 0 1 1 1 1 Clathrin light chain Hamartin PF04388.12 PRP83902.1 - 0.66 8.6 8.9 0.79 8.3 8.9 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2518 PF10726.9 PRP83904.1 - 0.42 10.3 3.9 8.6 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) Rad51 PF08423.11 PRP83905.1 - 4.4e-47 160.5 0.0 6e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 PRP83905.1 - 7.8e-10 38.5 0.0 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 PRP83905.1 - 1.3e-05 24.9 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 PRP83905.1 - 0.00016 21.1 0.1 0.002 17.5 0.1 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 PRP83905.1 - 0.0021 17.5 0.1 0.46 9.9 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_24 PF13479.6 PRP83905.1 - 0.075 12.7 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain E7 PF00527.18 PRP83905.1 - 1.2 9.4 4.6 0.7 10.1 1.2 2.4 3 0 0 3 3 3 0 E7 protein, Early protein NPCBM_assoc PF10633.9 PRP83906.1 - 0.014 15.7 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DUF756 PF05506.12 PRP83906.1 - 0.14 13.1 0.1 0.4 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF756) Phosphodiest PF01663.22 PRP83908.1 - 1.6e-09 37.8 0.4 6.6e-09 35.8 0.2 2.0 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 PRP83908.1 - 5.1e-06 26.0 0.2 9.5e-06 25.2 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily CPSase_L_D3 PF02787.19 PRP83908.1 - 0.073 13.4 0.2 0.18 12.1 0.2 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PglZ PF08665.12 PRP83908.1 - 0.078 13.1 1.7 0.35 10.9 0.3 2.3 2 0 0 2 2 2 0 PglZ domain SPRY PF00622.28 PRP83909.1 - 1.6e-29 102.4 0.2 2.8e-29 101.7 0.2 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 PRP83909.1 - 7.3e-19 68.1 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PRP83909.1 - 0.049 13.6 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 LisH FOP_dimer PF09398.10 PRP83909.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 FOP N terminal dimerisation domain Gp-FAR-1 PF05823.12 PRP83910.1 - 0.057 13.8 15.3 0.11 12.9 14.6 1.9 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF812 PF05667.11 PRP83910.1 - 4.1 6.2 37.7 1.8 7.3 27.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HMMR_N PF15905.5 PRP83910.1 - 4.9 6.5 47.6 0.19 11.1 23.2 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DSPc PF00782.20 PRP83911.1 - 3.9e-20 72.0 0.0 4.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP83911.1 - 0.033 13.8 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MORN PF02493.20 PRP83912.1 - 1.3e-23 81.4 33.3 3.5e-06 26.6 1.5 7.5 6 1 1 7 7 7 5 MORN repeat zf-C3HC4_3 PF13920.6 PRP83912.1 - 0.00032 20.5 3.0 0.0006 19.6 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP83912.1 - 0.0011 18.8 3.2 0.0021 17.9 3.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Taxilin PF09728.9 PRP83912.1 - 0.0059 15.8 18.7 0.0059 15.8 18.7 1.6 2 0 0 2 2 2 1 Myosin-like coiled-coil protein zf-C3HC4_2 PF13923.6 PRP83912.1 - 0.36 10.7 3.8 0.71 9.8 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4449 PF14613.6 PRP83912.1 - 1 9.5 7.8 0.95 9.6 6.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4449) Exonuc_VII_L PF02601.15 PRP83912.1 - 5.5 6.5 8.2 8.4 5.9 8.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IMD PF08397.11 PRP83912.1 - 7.6 5.8 15.2 14 4.9 15.2 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain Laminin_G_3 PF13385.6 PRP83913.1 - 1.1e-35 123.0 8.5 6.8e-19 68.5 0.1 2.9 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Toxin_R_bind_N PF07953.12 PRP83913.1 - 0.00027 20.7 2.0 0.89 9.2 0.0 3.0 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding DUF5012 PF16404.5 PRP83913.1 - 0.06 13.5 0.4 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5012) Laminin_G_2 PF02210.24 PRP83913.1 - 0.14 12.7 0.0 3.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Laminin G domain Carb_bind PF10645.9 PRP83913.1 - 4.2 7.7 33.3 0.29 11.4 5.2 3.9 3 1 1 4 4 4 0 Carbohydrate binding Na_H_Exchanger PF00999.21 PRP83914.1 - 4.2e-63 213.4 32.1 5.1e-63 213.1 32.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2062 PF09835.9 PRP83914.1 - 8.5 6.2 15.8 0.17 11.8 2.9 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) PIP5K PF01504.18 PRP83915.1 - 3.3e-60 203.6 4.7 8.5e-60 202.3 4.7 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sec3-PIP2_bind PF15277.6 PRP83915.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.0 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH ThiF PF00899.21 PRP83916.1 - 3.5e-92 308.2 0.0 2.6e-65 220.2 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 PRP83916.1 - 3.9e-68 230.1 0.0 6.1e-68 229.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 PRP83916.1 - 3.2e-28 97.7 0.1 6.4e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 PRP83916.1 - 4.7e-13 49.1 0.0 1.3e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 PRP83916.1 - 7.8e-13 48.9 0.0 1.8e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain HTH_CodY PF08222.11 PRP83916.1 - 0.12 12.0 0.0 0.47 10.0 0.0 2.0 1 1 0 1 1 1 0 CodY helix-turn-helix domain Stork_head PF10264.9 PRP83917.1 - 0.058 13.6 0.0 5.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain EF-hand_7 PF13499.6 PRP83918.1 - 4.2e-20 72.0 0.7 3.9e-12 46.4 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP83918.1 - 9.1e-19 65.6 10.1 1.2e-05 24.5 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PRP83918.1 - 4.4e-17 60.5 4.5 0.00039 20.1 0.1 5.0 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 PRP83918.1 - 1.3e-14 53.8 1.3 3.7e-06 26.7 0.0 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PRP83918.1 - 1e-11 43.8 9.0 1.6e-06 27.3 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 PRP83918.1 - 2.3e-07 30.7 0.7 8.6e-05 22.4 0.2 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PRP83918.1 - 0.00022 21.5 0.4 0.48 10.8 0.0 3.2 1 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 PRP83918.1 - 0.0095 16.8 0.3 2.5 9.0 0.1 2.5 1 1 0 2 2 2 1 EF-hand domain EF-hand_3 PF09069.11 PRP83918.1 - 0.018 15.5 1.0 2.5 8.6 0.1 2.6 2 1 0 2 2 2 0 EF-hand EF-hand_2 PF09068.11 PRP83918.1 - 0.063 13.4 0.6 0.12 12.5 0.2 1.6 2 0 0 2 2 2 0 EF hand EF-hand_14 PF17959.1 PRP83918.1 - 0.61 10.5 3.8 32 5.0 0.1 3.2 2 1 1 3 3 3 0 EF-hand domain Pkinase_Tyr PF07714.17 PRP83919.1 - 6.7e-61 205.8 0.0 1e-60 205.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83919.1 - 7.9e-55 186.0 0.0 1.3e-54 185.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 PRP83919.1 - 6.8e-12 44.0 0.0 0.0001 21.6 0.0 3.7 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 PRP83919.1 - 2.2e-11 42.7 0.2 0.0002 21.0 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 PRP83919.1 - 6.2e-10 39.4 0.0 0.0021 18.4 0.0 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP83919.1 - 3.4e-07 29.4 0.0 0.00019 20.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PRP83919.1 - 5.2e-05 23.0 0.4 0.69 9.8 0.0 3.8 4 1 1 5 5 5 2 EF-hand domain pair Haspin_kinase PF12330.8 PRP83919.1 - 0.00097 18.2 0.1 0.012 14.5 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain SPARC_Ca_bdg PF10591.9 PRP83919.1 - 0.016 15.5 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF1_GNE PF00736.19 PRP83919.1 - 0.047 13.9 0.1 7.6 6.8 0.0 2.6 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain Arv1 PF04161.13 PRP83921.1 - 1.2e-07 32.1 0.3 1.8e-07 31.5 0.3 1.2 1 0 0 1 1 1 1 Arv1-like family Pkinase PF00069.25 PRP83922.1 - 3.5e-52 177.4 0.0 4.7e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83922.1 - 1.1e-21 77.3 0.0 4.9e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP83922.1 - 7.7e-06 26.0 0.0 0.00029 20.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP83922.1 - 0.00066 19.3 0.2 0.0036 16.9 0.2 1.9 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 PRP83922.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 PRP83922.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MDM1 PF15501.6 PRP83923.1 - 0.025 13.7 1.2 0.042 13.0 1.3 1.3 1 1 0 1 1 1 0 Nuclear protein MDM1 AAA_15 PF13175.6 PRP83923.1 - 0.028 14.1 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DNA_pol_alpha_N PF12254.8 PRP83923.1 - 0.033 14.3 3.2 0.033 14.3 3.2 2.3 3 0 0 3 3 3 0 DNA polymerase alpha subunit p180 N terminal HTH_29 PF13551.6 PRP83924.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_11 PF08279.12 PRP83924.1 - 0.046 13.7 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 HTH domain HTH_22 PF13309.6 PRP83924.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 HTH domain HTH_Tnp_ISL3 PF13542.6 PRP83924.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 PRP83924.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Nuc_sug_transp PF04142.15 PRP83927.1 - 2e-50 171.8 20.4 5.1e-50 170.4 20.4 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 PRP83927.1 - 1.7e-07 31.5 27.4 0.00096 19.3 11.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PRP83927.1 - 0.00095 18.5 20.5 0.0049 16.1 20.5 2.2 1 1 0 1 1 1 1 UAA transporter family DUF4131 PF13567.6 PRP83927.1 - 1.4 8.5 0.0 1.4 8.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Nucleos_tra2_N PF01773.20 PRP83927.1 - 5 7.8 9.8 13 6.5 0.3 3.6 3 1 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Pkinase PF00069.25 PRP83928.1 - 1.2e-61 208.4 0.0 1.9e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP83928.1 - 2.9e-44 151.3 0.1 6e-44 150.3 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP83928.1 - 8.7e-10 39.1 0.0 2.9e-09 37.4 0.0 2.0 1 0 0 1 1 1 1 PH domain PBD PF00786.28 PRP83928.1 - 1.5e-06 28.5 0.1 5e-06 26.8 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 PRP83928.1 - 0.00032 19.6 0.0 0.0015 17.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase DUF4894 PF16235.5 PRP83928.1 - 0.18 12.2 0.1 1 9.8 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4894) GATase_7 PF13537.6 PRP83929.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 PRP83929.1 - 4.6e-11 42.5 0.0 8.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.6 PRP83929.1 - 1.4e-10 41.5 0.0 2.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.21 PRP83929.1 - 0.049 12.3 0.0 0.097 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II PRTase_2 PF15609.6 PRP83929.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase Pkinase_Tyr PF07714.17 PRP83930.1 - 1.4e-57 195.0 0.0 1.8e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP83930.1 - 1.7e-28 99.8 0.1 1.1e-26 93.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 PRP83930.1 - 1.1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP83930.1 - 0.00038 19.4 0.0 0.00047 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP83930.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain NPL4 PF05021.15 PRP83931.1 - 4e-64 216.9 0.0 2.6e-63 214.2 0.0 1.9 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 PRP83931.1 - 1.2e-35 122.8 0.5 2.9e-35 121.5 0.5 1.6 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 PRP83931.1 - 2.3e-10 40.8 0.0 5.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UBA PF00627.31 PRP83931.1 - 0.024 14.5 0.3 0.052 13.5 0.3 1.6 1 0 0 1 1 1 0 UBA/TS-N domain LIM PF00412.22 PRP83932.1 - 8.2e-63 208.5 62.3 2.6e-15 56.4 0.7 5.1 5 0 0 5 5 5 5 LIM domain ATPase-cat_bd PF12156.8 PRP83932.1 - 0.0067 17.1 2.5 0.0067 17.1 2.5 5.2 5 2 2 7 7 7 1 Putative metal-binding domain of cation transport ATPase DUF362 PF04015.12 PRP83932.1 - 0.037 14.2 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) DUF3268 PF11672.8 PRP83933.1 - 4.1 7.7 8.6 0.79 10.1 0.2 2.7 3 0 0 3 3 3 0 zinc-finger-containing domain DDE_Tnp_4 PF13359.6 PRP83935.1 - 4.2e-17 62.2 0.1 1.3e-12 47.7 0.0 2.2 2 0 0 2 2 2 2 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP83935.1 - 0.019 14.6 0.1 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Transposase DDE domain HTH_Tnp_4 PF13613.6 PRP83935.1 - 0.019 14.7 0.1 0.056 13.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease zf-RING_9 PF13901.6 PRP83937.1 - 3.5e-22 79.4 9.4 7.9e-21 75.0 0.0 2.7 1 1 1 2 2 2 2 Putative zinc-RING and/or ribbon Prok-RING_1 PF14446.6 PRP83937.1 - 1.1 9.3 8.1 0.83 9.6 4.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RUN PF02759.19 PRP83938.1 - 6.8e-22 77.9 2.4 1.1e-21 77.2 0.1 2.2 2 0 0 2 2 2 1 RUN domain Tti2 PF10521.9 PRP83939.1 - 0.0055 16.3 1.6 0.0055 16.3 1.6 2.2 3 0 0 3 3 3 1 Tti2 family DUF1722 PF08349.11 PRP83939.1 - 0.024 14.9 0.0 0.094 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) zf-C4H2 PF10146.9 PRP83940.1 - 0.041 14.2 1.0 0.046 14.0 1.0 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein Peptidase_M20 PF01546.28 PRP83941.1 - 1.4e-12 47.7 0.0 2.8e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PRP83941.1 - 7.5e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 PRP83941.1 - 0.13 11.3 0.0 3.1 6.7 0.0 2.4 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase 4HBT_3 PF13622.6 PRP83942.1 - 2.2e-20 74.0 0.0 2.8e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily GXWXG PF14231.6 PRP83942.1 - 0.043 13.9 0.0 0.44 10.7 0.0 2.3 2 0 0 2 2 2 0 GXWXG protein Snurportin1 PF11538.8 PRP83943.1 - 0.00042 20.4 6.0 0.00042 20.4 6.0 1.9 2 0 0 2 2 2 1 Snurportin1 TAF8_C PF10406.9 PRP83943.1 - 4.5 7.9 7.7 2.8 8.6 1.9 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term EIIA-man PF03610.16 PRP83944.1 - 0.22 11.8 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 PTS system fructose IIA component Cyclin_N PF00134.23 PRP83946.1 - 1.9e-18 66.5 2.8 2.8e-18 65.9 1.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP83946.1 - 0.0075 16.4 0.5 0.46 10.6 0.0 2.7 2 1 0 2 2 2 1 Cyclin, C-terminal domain PAP2 PF01569.21 PRP83948.1 - 2.7e-08 33.6 1.9 2.7e-08 33.6 1.9 3.0 2 1 1 3 3 3 1 PAP2 superfamily DUF883 PF05957.13 PRP83948.1 - 0.022 15.4 0.3 0.048 14.3 0.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF212 PF02681.14 PRP83948.1 - 0.038 14.1 0.0 0.15 12.2 0.0 2.1 1 1 1 2 2 2 0 Divergent PAP2 family GalKase_gal_bdg PF10509.9 PRP83950.1 - 1.7e-14 53.1 1.3 1.8e-14 53.0 0.1 1.7 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 PRP83950.1 - 2e-13 50.5 0.0 4.5e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 PRP83950.1 - 3.6e-11 43.1 0.2 9e-11 41.8 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain SET PF00856.28 PRP83951.1 - 0.00089 19.7 0.0 0.001 19.5 0.0 1.1 1 0 0 1 1 1 1 SET domain C2 PF00168.30 PRP83952.1 - 2.9e-25 88.5 0.0 6.7e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 PRP83952.1 - 0.044 14.4 0.1 4.1 8.1 0.0 3.1 3 0 0 3 3 3 0 Putative heavy-metal-binding AAA PF00004.29 PRP83953.1 - 5.8e-38 130.3 0.0 1.3e-37 129.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP83953.1 - 5e-11 42.2 0.0 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 PRP83953.1 - 3.9e-07 30.0 0.2 2e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 PRP83953.1 - 1.8e-05 24.6 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PRP83953.1 - 4.3e-05 23.7 0.0 8.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 PRP83953.1 - 7.6e-05 22.9 0.0 0.00048 20.3 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PRP83953.1 - 0.0005 20.5 0.3 0.16 12.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PRP83953.1 - 0.00098 19.1 0.2 0.0045 17.0 0.1 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PRP83953.1 - 0.0012 18.3 0.1 0.0025 17.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PRP83953.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 PRP83953.1 - 0.0031 18.1 0.3 0.02 15.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 PRP83953.1 - 0.0039 17.0 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 PRP83953.1 - 0.0041 17.4 0.3 0.043 14.1 0.2 2.5 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 PRP83953.1 - 0.0067 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 PRP83953.1 - 0.0074 16.3 0.0 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PRP83953.1 - 0.015 15.5 0.2 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 PRP83953.1 - 0.023 15.1 0.0 0.083 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PRP83953.1 - 0.043 13.3 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 PRP83953.1 - 0.049 13.0 0.3 6.6 6.0 0.1 2.4 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.6 PRP83953.1 - 0.053 13.2 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PRP83953.1 - 0.054 13.0 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 PRP83953.1 - 0.091 13.2 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 PRP83953.1 - 0.099 12.2 0.5 0.32 10.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain Fer2_4 PF13510.6 PRP83954.1 - 8.7e-19 67.4 1.9 2.6e-18 65.9 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 PRP83954.1 - 5.2e-15 54.7 0.8 5.2e-15 54.7 0.8 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 PRP83954.1 - 3.8e-09 36.4 4.5 7.7e-09 35.4 0.6 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 PRP83954.1 - 1.2 9.0 8.3 3.3 7.7 0.4 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain S1 PF00575.23 PRP83955.1 - 2.7e-22 78.9 12.6 3.4e-08 33.7 0.0 11.8 10 2 0 10 10 10 3 S1 RNA binding domain Suf PF05843.14 PRP83955.1 - 1.6e-10 41.5 8.0 2.5e-05 24.4 0.6 5.2 4 1 1 5 5 5 3 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 PRP83955.1 - 3.2e-08 33.1 18.7 1e-06 28.1 1.9 3.6 2 2 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 PRP83955.1 - 7.6e-06 26.3 0.1 0.82 10.7 0.0 4.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83955.1 - 3e-05 24.4 0.0 1.2 9.7 0.0 3.6 3 1 2 5 5 5 1 Tetratricopeptide repeat MRP-S35 PF10246.9 PRP83955.1 - 0.0035 17.3 0.1 7 6.7 0.0 3.6 3 0 0 3 3 3 1 Mitochondrial ribosomal protein MRP-S35 Utp13 PF08625.11 PRP83955.1 - 0.0081 16.1 0.3 0.02 14.8 0.3 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain TPR_15 PF13429.6 PRP83955.1 - 0.015 14.5 5.1 0.38 9.9 0.1 2.8 1 1 1 3 3 3 0 Tetratricopeptide repeat S1_2 PF13509.6 PRP83955.1 - 0.83 9.8 8.5 8.4 6.5 0.1 5.6 6 1 0 6 6 6 0 S1 domain DUF4585 PF15232.6 PRP83956.1 - 0.039 14.0 0.0 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) YEATS PF03366.16 PRP83957.1 - 4e-31 106.8 0.6 1e-30 105.5 0.6 1.7 1 0 0 1 1 1 1 YEATS family VWA PF00092.28 PRP83957.1 - 1.6e-14 54.5 1.2 5.2e-14 52.9 0.0 2.4 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP83957.1 - 2.8e-10 40.8 1.3 1.8e-09 38.2 0.0 2.9 3 1 1 4 4 4 1 von Willebrand factor type A domain VWA_3 PF13768.6 PRP83957.1 - 4.4e-10 39.7 0.4 1.1e-09 38.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain CLZ PF16526.5 PRP83957.1 - 0.2 12.0 1.7 0.48 10.8 0.3 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ARS2 PF04959.13 PRP83957.1 - 0.27 11.6 1.9 3.5 7.9 0.0 2.9 3 0 0 3 3 3 0 Arsenite-resistance protein 2 Adap_comp_sub PF00928.21 PRP83958.1 - 5e-86 288.3 0.0 6.5e-69 232.2 0.0 2.2 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PRP83958.1 - 1.8e-08 34.4 3.1 3.3e-08 33.6 3.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4246 PF14033.6 PRP83958.1 - 7.5e-06 25.3 0.1 1.1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) muHD PF10291.9 PRP83958.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Longin PF13774.6 PRP83958.1 - 0.18 11.9 0.1 0.37 10.8 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain Bromodomain PF00439.25 PRP83959.1 - 2.7e-10 40.2 0.3 7.8e-10 38.7 0.3 1.8 1 0 0 1 1 1 1 Bromodomain DUF1761 PF08570.10 PRP83960.1 - 0.005 17.1 4.0 0.005 17.1 4.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1761) DUF973 PF06157.11 PRP83960.1 - 5.6 5.9 8.7 0.23 10.5 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Adeno_E3B PF03376.14 PRP83961.1 - 0.09 13.0 0.8 0.16 12.2 0.3 1.7 2 0 0 2 2 2 0 Adenovirus E3B protein RhoGEF PF00621.20 PRP83963.1 - 4.8e-36 124.7 0.7 4.8e-36 124.7 0.7 3.0 2 1 0 2 2 2 1 RhoGEF domain C2 PF00168.30 PRP83963.1 - 3.6e-10 40.0 0.1 1.2e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 C2 domain Arm PF00514.23 PRP83963.1 - 5.6e-07 29.4 5.9 7.7 6.7 0.0 6.8 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Urb2 PF10441.9 PRP83963.1 - 0.0086 16.0 10.2 0.7 9.8 0.1 4.0 3 1 1 4 4 4 2 Urb2/Npa2 family IQ_SEC7_PH PF16453.5 PRP83963.1 - 0.01 15.8 0.5 0.03 14.3 0.1 1.9 2 0 0 2 2 2 0 PH domain EF-hand_2 PF09068.11 PRP83963.1 - 0.015 15.5 2.6 0.42 10.8 0.1 3.7 2 1 0 2 2 2 0 EF hand PH_13 PF16652.5 PRP83963.1 - 0.033 14.0 0.2 0.1 12.4 0.2 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 PRP83963.1 - 0.078 13.5 0.0 0.36 11.4 0.0 2.1 2 0 0 2 2 2 0 PH domain DUF4976 PF16347.5 PRP83964.1 - 0.0014 18.9 0.5 0.0083 16.4 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) MAD PF05557.13 PRP83965.1 - 4.6e-49 167.4 77.6 1e-47 163.0 77.5 2.1 1 1 0 1 1 1 1 Mitotic checkpoint protein Fez1 PF06818.15 PRP83965.1 - 0.0084 16.6 14.6 0.0084 16.6 14.6 4.4 2 1 2 5 5 5 1 Fez1 DivIC PF04977.15 PRP83965.1 - 0.53 10.1 0.0 0.53 10.1 0.0 9.6 9 3 1 10 10 10 0 Septum formation initiator NPV_P10 PF05531.12 PRP83965.1 - 1.1 9.7 0.0 1.1 9.7 0.0 6.2 6 3 1 7 7 7 0 Nucleopolyhedrovirus P10 protein RNaseH_C PF09293.10 PRP83965.1 - 4.5 7.6 9.3 0.27 11.6 0.6 3.1 3 0 0 3 3 3 0 T4 RNase H, C terminal HalX PF08663.10 PRP83965.1 - 6 7.3 22.3 0.89 9.9 0.1 6.7 5 2 2 7 7 7 0 HalX domain PARP PF00644.20 PRP83966.1 - 3.6e-68 229.0 0.0 3.6e-68 229.0 0.0 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PRP83966.1 - 2.5e-45 153.9 4.2 4.7e-45 153.0 4.2 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 PRP83966.1 - 1.5e-22 79.4 0.3 5.2e-22 77.7 0.3 1.9 1 0 0 1 1 1 1 WGR domain BRCT_2 PF16589.5 PRP83966.1 - 4.1e-14 52.8 0.1 1.3e-05 25.5 0.1 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PRP83966.1 - 4.7e-14 52.5 0.1 4.8e-11 42.9 0.3 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain WWE PF02825.20 PRP83966.1 - 2.2e-08 34.6 8.0 3e-07 30.9 6.9 2.8 2 0 0 2 2 2 1 WWE domain PTCB-BRCT PF12738.7 PRP83966.1 - 0.0091 15.9 0.0 0.98 9.4 0.1 2.5 2 0 0 2 2 2 1 twin BRCT domain VirDNA-topo-I_N PF09266.10 PRP83966.1 - 0.035 14.3 0.4 6 7.1 0.0 3.7 3 0 0 3 3 3 0 Viral DNA topoisomerase I, N-terminal FapA PF03961.13 PRP83967.1 - 0.025 13.2 3.3 0.029 13.0 3.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 PRP83967.1 - 2 8.6 8.1 5.9 7.1 8.1 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 PRP83967.1 - 2.4 7.3 7.0 3.9 6.6 7.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.12 PRP83967.1 - 6.8 5.1 5.9 7.7 4.9 5.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_C14 PF00656.22 PRP83968.1 - 0.00093 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Methyltr_RsmB-F PF01189.17 PRP83969.1 - 1.9e-22 79.9 0.0 4.4e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PRP83969.1 - 0.032 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CDC45 PF02724.14 PRP83969.1 - 0.43 8.8 13.5 0.57 8.4 13.5 1.3 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 PRP83972.1 - 1.6e-43 149.0 50.0 2.1e-42 145.3 50.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 PRP83972.1 - 4e-11 42.1 24.6 5.6e-11 41.6 24.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC_tran PF00005.27 PRP83974.1 - 9.9e-27 94.1 0.1 2.1e-26 93.1 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP83974.1 - 1.4e-18 67.2 5.8 2.2e-18 66.5 5.8 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP83974.1 - 7.5e-12 45.7 1.5 1.5e-09 38.1 0.0 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PRP83974.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 PRP83974.1 - 0.008 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 PRP83974.1 - 0.054 12.9 0.2 1.6 8.1 0.2 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PRP83974.1 - 0.072 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 PRP83974.1 - 0.074 13.5 1.5 0.2 12.1 1.6 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP83974.1 - 0.17 11.7 0.7 0.46 10.3 0.7 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PRP83974.1 - 0.21 10.9 0.9 3.5 6.8 0.1 2.5 3 0 0 3 3 3 0 Zeta toxin AAA_22 PF13401.6 PRP83974.1 - 0.25 11.6 0.4 0.85 9.9 0.1 2.0 1 1 1 2 2 2 0 AAA domain PIH1_CS PF18201.1 PRP83976.1 - 3.2e-14 53.1 0.1 6.3e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain HSP20 PF00011.21 PRP83976.1 - 0.058 13.6 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 Hsp20/alpha crystallin family HypF_C PF17788.1 PRP83976.1 - 0.084 13.6 0.1 0.14 12.9 0.1 1.3 1 0 0 1 1 1 0 HypF Kae1-like domain Mersacidin PF16934.5 PRP83976.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) Ras PF00071.22 PRP83977.1 - 1.1e-25 90.2 0.0 1.2e-14 54.2 0.0 2.5 1 1 1 2 2 2 2 Ras family BTB PF00651.31 PRP83977.1 - 9.6e-14 51.6 0.1 1.2e-05 25.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Roc PF08477.13 PRP83977.1 - 0.00048 20.3 0.0 0.0032 17.7 0.0 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FAM167 PF11652.8 PRP83977.1 - 0.095 13.2 0.1 0.52 10.8 0.1 2.3 1 0 0 1 1 1 0 FAM167 AAA_28 PF13521.6 PRP83977.1 - 0.21 11.8 1.3 4.1 7.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF2054 PF10218.9 PRP83980.1 - 5.8e-32 110.6 17.9 1.2e-31 109.6 17.9 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) Peptidase_C2 PF00648.21 PRP83981.1 - 1.1e-84 284.0 0.0 1.5e-84 283.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PRP83981.1 - 3.6e-22 79.1 0.0 1.8e-21 76.8 0.0 2.2 2 0 0 2 2 2 1 Calpain large subunit, domain III TPR_7 PF13176.6 PRP83981.1 - 2e-06 27.4 0.3 0.18 11.9 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP83981.1 - 2.3e-06 27.8 2.2 0.05 13.9 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP83981.1 - 0.00022 21.1 2.1 6.2 7.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP83981.1 - 0.0016 18.2 0.0 0.68 9.9 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Cohesin_load PF10345.9 PRP83981.1 - 0.019 13.4 0.2 0.03 12.8 0.2 1.2 1 0 0 1 1 1 0 Cohesin loading factor UQ_con PF00179.26 PRP83982.1 - 8.3e-49 164.8 0.1 1e-48 164.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PRP83982.1 - 0.13 12.6 0.9 0.23 11.8 0.9 1.9 1 1 0 1 1 1 0 RWD domain NOA36 PF06524.12 PRP83982.1 - 5.4 6.2 6.0 6.4 6.0 6.0 1.1 1 0 0 1 1 1 0 NOA36 protein AAA PF00004.29 PRP83983.1 - 3.8e-16 59.7 0.2 1.6e-15 57.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP83983.1 - 2.5e-10 40.7 0.0 5.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP83983.1 - 2.9e-10 40.8 0.1 4.5e-09 36.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 PRP83983.1 - 3.8e-08 33.4 0.2 9.3e-08 32.1 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain Cdc6_C PF09079.11 PRP83983.1 - 3.5e-06 26.9 0.0 9.4e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain DUF2075 PF09848.9 PRP83983.1 - 1.5e-05 24.4 0.0 2.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 PRP83983.1 - 0.00061 19.4 0.2 0.0012 18.5 0.2 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 PRP83983.1 - 0.00077 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ORC2 PF04084.14 PRP83983.1 - 0.00081 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF815 PF05673.13 PRP83983.1 - 0.0032 16.7 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 PRP83983.1 - 0.0043 17.4 0.2 0.019 15.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain Zot PF05707.12 PRP83983.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ResIII PF04851.15 PRP83983.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF5318 PF17249.2 PRP83983.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5318) IBN_N PF03810.19 PRP83984.1 - 2.6e-09 36.9 0.4 7.9e-09 35.3 0.1 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 PRP83984.1 - 0.027 14.5 0.8 0.24 11.5 0.1 2.8 2 0 0 2 2 2 0 Exportin 1-like protein V-ATPase_H_C PF11698.8 PRP83984.1 - 0.036 14.2 0.0 17 5.6 0.0 3.3 3 0 0 3 3 3 0 V-ATPase subunit H Kelch_4 PF13418.6 PRP83985.1 - 2e-20 72.5 5.1 1.5e-08 34.5 0.0 6.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 PRP83985.1 - 2.2e-18 66.0 0.9 0.0045 17.2 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP83985.1 - 7e-13 48.3 0.1 0.0013 18.7 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PRP83985.1 - 1.6e-12 47.2 2.8 0.002 18.4 0.0 6.3 4 2 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 PRP83985.1 - 3.6e-08 33.1 2.8 3.3 7.8 0.1 5.6 4 2 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 PRP83985.1 - 4.3e-08 32.6 3.9 0.00097 18.7 0.1 4.4 5 1 0 5 5 5 2 Kelch motif RhoGEF PF00621.20 PRP83986.1 - 2.9e-43 148.2 4.2 6.2e-43 147.2 4.2 1.6 1 0 0 1 1 1 1 RhoGEF domain PHD PF00628.29 PRP83986.1 - 1.3e-06 28.1 6.9 2.9e-06 27.1 6.9 1.6 1 0 0 1 1 1 1 PHD-finger PH PF00169.29 PRP83986.1 - 5.8e-06 26.8 2.0 2.3e-05 24.8 0.4 2.5 1 1 1 2 2 2 1 PH domain IQ_SEC7_PH PF16453.5 PRP83986.1 - 4.9e-05 23.3 2.0 0.00012 22.1 2.0 1.5 1 0 0 1 1 1 1 PH domain HARE-HTH PF05066.13 PRP83986.1 - 0.00022 21.6 0.0 0.00058 20.2 0.0 1.7 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain PH_5 PF15405.6 PRP83986.1 - 0.0076 16.4 0.7 3.4 7.8 0.1 3.3 1 1 1 2 2 2 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 PRP83986.1 - 0.0099 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 ELMO/CED-12 family zf-HC5HC2H PF13771.6 PRP83986.1 - 0.013 15.7 0.4 0.052 13.8 0.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain PH_13 PF16652.5 PRP83986.1 - 4.1 7.2 18.2 0.16 11.7 8.1 3.3 3 1 0 3 3 3 0 Pleckstrin homology domain LRR_8 PF13855.6 PRP83987.1 - 4.4e-37 125.6 41.7 8.3e-11 41.5 2.4 8.2 6 1 2 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 PRP83987.1 - 6.5e-20 70.9 58.3 4.2e-06 27.0 3.6 11.6 5 3 5 13 13 13 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP83987.1 - 3.9e-13 48.0 37.2 0.25 12.0 0.3 14.1 13 1 0 13 13 13 4 Leucine Rich Repeat GPS PF01825.21 PRP83987.1 - 2.6e-08 34.2 1.0 6.8e-08 32.9 1.0 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_6 PF13516.6 PRP83987.1 - 1.2e-06 28.1 23.1 0.37 11.0 0.6 9.4 8 1 1 9 9 9 2 Leucine Rich repeat TMEM154 PF15102.6 PRP83987.1 - 0.036 14.0 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family CwsA PF10814.8 PRP83987.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA LRR_8 PF13855.6 PRP83989.1 - 5.5e-26 90.1 53.3 6.6e-10 38.6 8.3 7.9 5 2 2 8 8 8 7 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP83989.1 - 1.2e-17 64.1 0.3 3.5e-15 56.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PRP83989.1 - 2.7e-13 49.8 62.0 0.00084 19.7 4.5 9.5 3 2 10 13 13 13 12 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP83989.1 - 7.1e-09 35.4 0.2 5.1e-07 29.3 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP83989.1 - 1.2e-07 32.2 1.1 2.3e-07 31.2 1.1 1.5 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP83989.1 - 0.0078 16.6 55.4 7.7 7.5 0.5 12.8 13 1 0 13 13 13 3 Leucine Rich Repeat Utp14 PF04615.13 PRP83990.1 - 3.7e-52 178.0 95.5 3.7e-52 178.0 95.5 2.6 1 1 1 2 2 2 1 Utp14 protein LRR_8 PF13855.6 PRP83991.1 - 1.1e-34 118.0 89.2 1.3e-06 28.0 2.0 12.5 6 2 3 12 12 12 10 Leucine rich repeat LRR_4 PF12799.7 PRP83991.1 - 4.7e-24 84.1 101.2 8e-05 22.9 0.3 16.1 10 3 5 16 16 16 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP83991.1 - 6.3e-13 47.3 96.6 0.084 13.5 0.1 23.9 23 3 0 23 23 23 5 Leucine Rich Repeat Pkinase_Tyr PF07714.17 PRP83991.1 - 2.1e-10 40.3 0.9 6.8e-09 35.4 0.1 2.5 1 1 1 2 2 2 1 Protein tyrosine kinase GPS PF01825.21 PRP83991.1 - 7.8e-08 32.7 0.4 1.8e-07 31.6 0.4 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP83991.1 - 0.00083 18.8 0.3 0.021 14.2 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain LRR_6 PF13516.6 PRP83991.1 - 0.14 12.3 80.6 0.27 11.4 0.4 18.3 20 0 0 20 20 20 0 Leucine Rich repeat Lipocalin_4 PF13648.6 PRP83991.1 - 2.8 9.0 8.5 12 7.0 0.2 4.1 4 0 0 4 4 4 0 Lipocalin-like domain DUF2664 PF10867.8 PRP83992.1 - 3.9 8.0 13.5 53 4.4 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2664) NDT80_PhoG PF05224.12 PRP83993.1 - 0.016 15.4 0.6 0.055 13.7 0.7 1.7 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family HEXIM PF15313.6 PRP83993.1 - 0.029 14.6 0.6 0.037 14.2 0.6 1.1 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein DUF1857 PF08982.11 PRP83994.1 - 0.075 12.9 0.9 0.13 12.1 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1857) Palm_thioest PF02089.15 PRP83995.1 - 1.4e-06 28.3 0.0 5e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 PRP83995.1 - 0.0011 18.7 0.1 0.82 9.3 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.13 PRP83995.1 - 0.0019 18.0 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein LCAT PF02450.15 PRP83995.1 - 0.034 13.3 0.0 0.27 10.3 0.0 2.1 1 1 1 2 2 2 0 Lecithin:cholesterol acyltransferase ASH PF15780.5 PRP83995.1 - 0.16 12.2 0.7 7.2 6.9 0.1 2.4 1 1 1 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin VPS9 PF02204.18 PRP83996.1 - 7.1e-15 55.1 0.0 3e-14 53.1 0.0 2.1 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.20 PRP83996.1 - 1.6e-06 27.7 10.1 3.1e-05 23.6 0.2 5.3 7 0 0 7 7 7 2 MORN repeat WD40 PF00400.32 PRP83996.1 - 0.0002 22.1 5.1 0.2 12.6 0.4 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat PB1 PF00564.24 PRP83997.1 - 2.6e-13 49.7 0.1 5e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 PB1 domain zf-C4_Topoisom PF01396.19 PRP83997.1 - 2.8e-05 23.8 2.2 2.8e-05 23.8 2.2 2.0 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger TPR_2 PF07719.17 PRP83998.1 - 3.6e-16 57.9 9.9 1.1e-05 25.1 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP83998.1 - 1.1e-13 50.3 10.2 2e-05 24.2 0.0 7.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP83998.1 - 6.4e-11 42.6 0.8 0.011 16.2 0.0 6.7 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP83998.1 - 9e-10 38.6 7.0 0.49 11.4 0.0 8.1 7 2 2 9 9 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP83998.1 - 3.3e-09 37.2 0.5 8.2e-07 29.6 0.0 4.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP83998.1 - 4.2e-09 35.9 15.1 0.041 14.1 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP83998.1 - 9.3e-09 35.1 0.1 0.03 14.7 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP83998.1 - 1.2e-08 34.5 0.2 0.042 13.5 0.0 5.2 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.6 PRP83998.1 - 3.3e-08 33.7 1.1 0.94 9.8 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP83998.1 - 8.4e-07 28.6 0.9 14 6.0 0.0 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 PRP83998.1 - 3e-05 23.4 3.1 0.094 11.9 0.1 3.3 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP83998.1 - 0.00055 20.4 11.1 0.16 12.6 0.0 7.4 9 0 0 9 9 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP83998.1 - 0.00061 20.0 1.7 0.072 13.3 0.3 4.3 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PRP83998.1 - 0.00086 19.4 0.4 0.037 14.2 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP83998.1 - 0.0061 16.4 5.9 20 5.2 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat PAN_4 PF14295.6 PRP83999.1 - 7.7e-07 28.9 6.4 7.7e-07 28.9 6.4 3.0 2 0 0 2 2 2 1 PAN domain Chitin_bind_1 PF00187.19 PRP83999.1 - 2.2e-06 28.0 20.5 2.2e-06 28.0 20.5 3.2 2 0 0 2 2 2 1 Chitin recognition protein Glyco_hydro_16 PF00722.21 PRP83999.1 - 4.1e-06 26.4 0.0 7.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1992 PF09350.10 PRP84001.1 - 0.078 13.1 0.2 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) Arif-1 PF06770.11 PRP84002.1 - 0.052 13.2 1.1 0.087 12.5 0.9 1.4 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) Syndecan PF01034.20 PRP84002.1 - 0.095 12.6 0.3 0.23 11.4 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain E1-E2_ATPase PF00122.20 PRP84004.1 - 4.2e-50 169.8 3.3 1.3e-49 168.2 3.3 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PRP84004.1 - 9.5e-34 116.7 1.2 9.5e-34 116.7 1.2 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 PRP84004.1 - 5.8e-16 57.9 0.0 1.5e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 PRP84004.1 - 1.5e-15 58.1 0.1 4.4e-14 53.3 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP84004.1 - 8.8e-12 45.0 0.1 2.8e-11 43.3 0.1 2.0 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP84004.1 - 5.1e-05 23.1 0.3 5.1e-05 23.1 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF5093 PF17011.5 PRP84004.1 - 0.52 10.6 4.0 1.3 9.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) RNA_polI_A34 PF08208.11 PRP84004.1 - 0.58 10.2 17.3 0.19 11.8 12.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.12 PRP84004.1 - 0.91 9.7 4.9 0.24 11.6 1.6 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family U1snRNP70_N PF12220.8 PRP84004.1 - 1.2 9.8 11.5 1.1 9.9 5.6 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CDC45 PF02724.14 PRP84004.1 - 2.3 6.4 4.6 1.8 6.7 3.1 1.5 2 0 0 2 2 2 0 CDC45-like protein TT_ORF2 PF02957.15 PRP84004.1 - 4.1 8.3 7.5 1.3 10.0 4.2 1.8 2 0 0 2 2 1 0 TT viral ORF2 PTPRCAP PF15713.5 PRP84004.1 - 4.8 7.5 12.9 2 8.7 8.4 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 PRP84004.1 - 5.4 6.8 12.2 9.6 5.9 9.5 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PH PF00169.29 PRP84005.1 - 3.2e-14 53.3 0.9 7.2e-14 52.2 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 PRP84005.1 - 7.2e-06 26.2 0.1 2.4e-05 24.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain AA_permease_2 PF13520.6 PRP84005.1 - 0.012 14.4 1.5 0.017 14.0 1.5 1.1 1 0 0 1 1 1 0 Amino acid permease DUF5635 PF18685.1 PRP84005.1 - 0.85 9.6 2.7 24 4.9 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5635) Glucan_synthase PF02364.15 PRP84007.1 - 9.8e-72 242.3 20.1 2e-71 241.3 16.8 2.8 2 1 0 2 2 2 1 1,3-beta-glucan synthase component CdiA_C_tRNase PF18664.1 PRP84007.1 - 0.14 12.4 0.2 0.35 11.1 0.2 1.6 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain EF-hand_1 PF00036.32 PRP84008.1 - 5.7e-27 91.2 1.9 1.4e-06 27.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PRP84008.1 - 5.6e-21 72.6 2.9 3.9e-05 23.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 PRP84008.1 - 6.7e-21 74.5 3.5 2.6e-11 43.8 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP84008.1 - 8e-18 63.1 5.8 0.00039 19.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 PRP84008.1 - 2.7e-15 55.9 3.7 8.6e-07 28.7 0.1 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_11 PF08976.11 PRP84008.1 - 3.6e-07 31.0 0.1 1.5e-05 25.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 PRP84008.1 - 0.0046 16.8 1.0 0.57 10.1 0.1 3.0 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 PRP84008.1 - 0.0068 16.7 0.5 9 6.7 0.0 3.0 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 PRP84008.1 - 0.12 10.9 0.0 0.33 9.4 0.0 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Pkinase PF00069.25 PRP84009.1 - 7e-42 143.6 0.0 8e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84009.1 - 2.5e-19 69.6 0.0 2.8e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP84009.1 - 6.9e-05 22.3 0.0 0.029 13.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PRP84009.1 - 0.0002 20.8 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP84009.1 - 0.00037 20.5 0.0 0.00084 19.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP84009.1 - 0.024 13.6 0.0 0.047 12.6 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Imm7 PF15585.6 PRP84009.1 - 0.055 13.8 0.0 0.099 12.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 7 Carb_bind PF10645.9 PRP84010.1 - 0.0027 17.9 6.1 0.0027 17.9 6.1 5.4 2 2 2 4 4 4 1 Carbohydrate binding SH2 PF00017.24 PRP84011.1 - 8.5e-18 64.2 0.1 9.7e-08 32.0 0.0 2.7 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP84011.1 - 2.4e-08 34.6 0.2 6.2e-08 33.2 0.2 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain IBP39 PF11422.8 PRP84011.1 - 0.00045 20.0 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Initiator binding protein 39 kDa CtIP_N PF10482.9 PRP84011.1 - 0.0032 17.5 3.4 0.0089 16.1 3.4 1.7 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain SH2 PF00017.24 PRP84013.1 - 3.5e-12 46.2 0.1 5.3e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP84013.1 - 4.8e-08 33.6 0.0 1.4e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain IBP39 PF11422.8 PRP84013.1 - 0.00061 19.6 0.1 0.0014 18.4 0.1 1.6 1 0 0 1 1 1 1 Initiator binding protein 39 kDa Cbl_N3 PF02762.14 PRP84013.1 - 0.065 13.1 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Pentaxin PF00354.17 PRP84013.1 - 0.17 11.5 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Pentaxin family SH2 PF00017.24 PRP84014.1 - 1.9e-13 50.3 0.0 2.9e-07 30.5 0.1 2.9 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP84014.1 - 1.1e-07 32.5 1.1 1.1e-06 29.3 0.8 2.5 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain IBP39 PF11422.8 PRP84014.1 - 0.00098 18.9 0.1 0.0029 17.4 0.1 1.8 1 1 0 1 1 1 1 Initiator binding protein 39 kDa Pentaxin PF00354.17 PRP84014.1 - 0.053 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Pentaxin family SH2 PF00017.24 PRP84015.1 - 2.2e-30 104.5 0.4 1.6e-06 28.1 0.1 5.1 5 0 0 5 5 5 4 SH2 domain Cbl_N2 PF02761.14 PRP84015.1 - 1.6e-19 70.4 1.9 1.4e-08 35.3 0.3 3.0 2 0 0 2 2 2 2 CBL proto-oncogene N-terminus, EF hand-like domain IBP39 PF11422.8 PRP84015.1 - 3e-09 36.9 0.3 0.0029 17.4 0.1 2.5 2 0 0 2 2 2 2 Initiator binding protein 39 kDa Pentaxin PF00354.17 PRP84015.1 - 3.6e-05 23.5 0.4 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 Pentaxin family ApoC-I PF04691.12 PRP84015.1 - 0.0026 17.6 2.4 0.34 10.9 0.5 2.4 2 0 0 2 2 2 1 Apolipoprotein C-I (ApoC-1) Cbl_N3 PF02762.14 PRP84015.1 - 0.0048 16.7 0.0 0.36 10.7 0.0 3.1 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, SH2-like domain Pedibin PF08182.11 PRP84015.1 - 0.12 12.2 2.6 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Pedibin/Hym-346 family NosL PF05573.12 PRP84015.1 - 0.12 12.7 0.1 48 4.3 0.0 3.2 4 0 0 4 4 3 0 NosL ABC_tran_CTD PF16326.5 PRP84015.1 - 0.13 12.5 14.5 0.16 12.2 1.7 3.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain DUF2408 PF10303.9 PRP84015.1 - 0.18 12.3 3.1 3 8.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Fib_alpha PF08702.10 PRP84015.1 - 0.25 11.5 9.0 2.6 8.2 1.1 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Phage_holin_7_1 PF16081.5 PRP84015.1 - 1.2 9.3 5.2 0.24 11.6 0.8 1.9 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family ASD2 PF08687.11 PRP84015.1 - 1.5 8.4 11.8 1.2 8.6 6.6 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 Dynactin_p22 PF07426.11 PRP84015.1 - 1.5 8.6 7.8 2.5 7.9 0.2 2.7 2 0 0 2 2 2 0 Dynactin subunit p22 HAUS-augmin3 PF14932.6 PRP84015.1 - 1.9 8.0 11.0 0.82 9.2 3.9 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 PRP84015.1 - 2.2 7.5 7.1 2.8 7.2 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 PRP84015.1 - 2.5 8.2 5.7 3.7 7.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CdvA PF18822.1 PRP84015.1 - 2.8 7.8 6.7 4.4 7.2 1.2 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Mod_r PF07200.13 PRP84015.1 - 3.2 7.9 11.4 7.1 6.7 0.7 2.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Apolipoprotein PF01442.18 PRP84015.1 - 3.4 7.5 11.2 2.2 8.1 1.3 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain TolA_bind_tri PF16331.5 PRP84015.1 - 3.5 7.8 12.5 0.43 10.7 4.1 2.9 2 1 0 2 2 2 0 TolA binding protein trimerisation Tetraspanin PF00335.20 PRP84016.1 - 0.52 10.0 24.2 0.036 13.8 16.8 2.0 1 1 0 2 2 2 0 Tetraspanin family CD20 PF04103.15 PRP84016.1 - 0.92 9.6 12.5 2.7 8.1 12.5 1.8 1 1 0 1 1 1 0 CD20-like family Nodulin_late PF07127.11 PRP84016.1 - 5.1 7.5 6.6 0.79 10.1 0.2 2.8 2 1 1 3 3 3 0 Late nodulin protein ZZ PF00569.17 PRP84017.1 - 8.3e-10 38.3 6.7 1.7e-09 37.3 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 PRP84017.1 - 0.00034 20.5 0.2 0.00062 19.7 0.2 1.4 1 0 0 1 1 1 1 PB1 domain zf-RING_10 PF16685.5 PRP84017.1 - 0.82 9.9 6.2 2.8 8.1 5.5 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 PRP38_assoc PF12871.7 PRP84017.1 - 1.5 9.4 8.3 0.47 11.1 5.0 1.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Far-17a_AIG1 PF04750.14 PRP84018.1 - 5.3e-27 94.5 16.8 6.8e-27 94.1 16.8 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Orai-1 PF07856.12 PRP84018.1 - 0.019 14.7 7.6 0.059 13.1 7.6 1.7 1 1 0 1 1 1 0 Mediator of CRAC channel activity Actin PF00022.19 PRP84019.1 - 1.1e-146 488.6 0.0 4e-146 486.8 0.0 1.7 1 1 0 1 1 1 1 Actin TMEM220 PF15071.6 PRP84020.1 - 1e-19 71.2 1.1 2.6e-19 69.9 0.3 1.8 2 0 0 2 2 2 1 Transmembrane family 220, helix YbhQ PF11076.8 PRP84020.1 - 0.053 13.5 1.6 0.055 13.5 0.0 1.8 2 1 1 3 3 3 0 Putative inner membrane protein YbhQ Peptidase_C97 PF05903.14 PRP84021.1 - 1.3e-34 119.2 0.0 1.8e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain RhoGEF PF00621.20 PRP84022.1 - 4.4e-48 163.9 2.6 8.2e-48 163.0 2.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PRP84022.1 - 7.8e-28 97.1 2.8 6.5e-18 65.2 0.0 3.6 2 1 0 3 3 3 3 PH domain PH_11 PF15413.6 PRP84022.1 - 1e-06 29.1 5.1 0.00015 22.2 1.3 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 PRP84022.1 - 6.3e-05 23.0 0.1 0.038 13.9 0.0 2.7 2 0 0 2 2 2 2 PH domain PH_6 PF15406.6 PRP84022.1 - 6.8e-05 23.1 0.0 0.24 11.7 0.1 2.8 2 0 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 PRP84022.1 - 0.00024 21.0 0.9 1.9 8.3 0.1 3.5 3 0 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 PRP84022.1 - 0.0094 16.0 0.1 0.054 13.6 0.0 2.2 2 0 0 2 2 2 1 PH domain zf-C2H2_4 PF13894.6 PRP84022.1 - 0.017 15.9 0.2 0.082 13.8 0.2 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger Sina PF03145.16 PRP84022.1 - 0.035 14.1 0.4 0.43 10.5 0.1 2.3 2 0 0 2 2 2 0 Seven in absentia protein family zf-C2H2 PF00096.26 PRP84022.1 - 0.048 14.1 0.2 0.15 12.6 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type L31 PF09784.9 PRP84023.1 - 8.7 6.8 13.4 0.88 10.0 1.7 3.2 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 Glyco_trans_1_4 PF13692.6 PRP84024.1 - 1.1e-11 45.3 0.0 2.4e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PRP84024.1 - 3.7e-11 42.8 0.0 1.6e-10 40.7 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PRP84024.1 - 0.00087 19.6 0.0 0.0049 17.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 LEA_4 PF02987.16 PRP84025.1 - 4.4e-05 23.5 43.8 0.016 15.3 4.3 4.4 1 1 3 4 4 4 4 Late embryogenesis abundant protein DUF1103 PF06513.11 PRP84025.1 - 3.6 7.1 18.2 39 3.7 18.1 2.1 2 1 0 2 2 2 0 Repeat of unknown function (DUF1103) Bactofilin PF04519.13 PRP84025.1 - 7.3 7.0 16.4 2 8.8 8.2 2.8 1 1 1 2 2 2 0 Polymer-forming cytoskeletal Vps62 PF06101.11 PRP84026.1 - 0.00017 20.1 0.1 0.0021 16.4 0.0 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 RicinB_lectin_2 PF14200.6 PRP84026.1 - 0.001 19.7 2.4 0.11 13.2 0.0 3.9 4 0 0 4 4 4 1 Ricin-type beta-trefoil lectin domain-like SAP PF02037.27 PRP84027.1 - 1e-07 31.5 0.2 1.6e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 SAP domain dsDNA_bind PF01984.20 PRP84027.1 - 0.024 14.9 0.2 0.057 13.7 0.1 1.7 1 1 0 1 1 1 0 Double-stranded DNA-binding domain Guanylate_cyc PF00211.20 PRP84029.1 - 2.8e-53 180.3 0.3 8.8e-29 100.4 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PRP84029.1 - 0.086 12.3 1.3 2.5 7.5 0.4 2.3 2 0 0 2 2 2 0 Heme NO binding associated ADH_N PF08240.12 PRP84031.1 - 2.9e-31 107.6 1.0 8.9e-31 106.0 1.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PRP84031.1 - 6.8e-25 87.5 0.9 1.3e-24 86.7 0.9 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PRP84031.1 - 5.5e-13 48.9 2.0 2.1e-12 47.0 2.0 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 PRP84031.1 - 2.7e-06 28.4 0.1 7.8e-06 27.0 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PRP84031.1 - 0.0047 16.3 3.2 0.01 15.2 3.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_31 PF13847.6 PRP84031.1 - 0.011 15.5 0.2 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain ISG65-75 PF11727.8 PRP84031.1 - 0.088 12.0 5.4 0.52 9.5 0.1 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein Methyltransf_25 PF13649.6 PRP84031.1 - 0.099 13.4 0.1 0.25 12.1 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain SNARE PF05739.19 PRP84031.1 - 0.15 12.1 0.1 0.83 9.7 0.3 2.2 2 0 0 2 2 2 0 SNARE domain SKA1 PF07160.12 PRP84031.1 - 1.7 8.4 10.0 3.9 7.3 0.4 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF745 PF05335.13 PRP84031.1 - 2.5 7.8 10.6 3.1 7.5 4.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 PRP84031.1 - 5.6 7.0 7.1 8.4 6.5 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_S10 PF00450.22 PRP84032.1 - 2.5e-125 419.2 5.7 3e-125 418.9 5.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.25 PRP84033.1 - 1.1e-66 224.9 0.0 1.5e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84033.1 - 3.9e-35 121.4 0.0 5.4e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PRP84033.1 - 2.5e-08 34.5 0.3 5.3e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 PRP84033.1 - 3.2e-07 30.0 0.0 1.2e-06 28.0 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PRP84033.1 - 4.4e-06 25.9 0.1 5.8e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP84033.1 - 0.00031 20.2 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP84033.1 - 0.0017 17.2 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 PRP84033.1 - 0.0049 16.5 0.5 0.63 9.6 0.1 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PRP84033.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 PRP84034.1 - 8e-08 33.2 0.8 1.1e-07 32.7 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP84034.1 - 1.5e-06 27.6 0.0 2.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP84034.1 - 8.3e-06 25.6 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 PRP84034.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 PRP84034.1 - 0.00016 21.3 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF1725 PF08333.11 PRP84034.1 - 0.078 12.7 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) DUF2612 PF11041.8 PRP84034.1 - 0.12 12.3 0.1 1.5 8.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2612) Histone PF00125.24 PRP84035.1 - 3.3e-22 79.3 0.9 4.5e-22 78.8 0.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PRP84035.1 - 0.00015 22.0 0.3 0.00015 22.0 0.3 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PRP84035.1 - 0.012 16.1 0.1 0.022 15.3 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 PRP84035.1 - 0.02 14.9 0.9 0.025 14.6 0.9 1.2 1 0 0 1 1 1 0 YscO-like protein Ribosomal_S30 PF04758.14 PRP84035.1 - 0.26 11.5 6.6 0.1 12.8 3.4 2.1 2 0 0 2 2 2 0 Ribosomal protein S30 ubiquitin PF00240.23 PRP84036.1 - 1.9e-10 40.3 0.0 4.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 PRP84036.1 - 2.4e-06 28.1 0.0 3.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP84036.1 - 0.0034 17.5 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cytochrome-c551 PF10643.9 PRP84036.1 - 0.67 9.5 2.1 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 IBN_N PF03810.19 PRP84037.1 - 7.9e-06 25.7 0.0 0.00019 21.3 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 PRP84037.1 - 2.1e-05 24.6 0.1 0.0028 17.7 0.0 4.4 5 1 0 5 5 5 1 Exportin 1-like protein DUF3294 PF07957.11 PRP84037.1 - 0.064 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) Adeno_100 PF02438.16 PRP84037.1 - 0.068 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Late 100kD protein HEAT PF02985.22 PRP84037.1 - 0.09 13.1 2.9 33 5.1 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat RIX1 PF08167.12 PRP84037.1 - 0.73 9.5 7.5 0.27 10.9 0.1 3.2 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis HOASN PF14515.6 PRP84038.1 - 0.038 14.4 0.3 0.17 12.3 0.1 2.0 1 1 1 2 2 2 0 Haem-oxygenase-associated N-terminal helices UPF0556 PF10572.9 PRP84039.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 MTHFR PF02219.17 PRP84040.1 - 0.00059 19.2 0.0 0.00082 18.8 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Pkinase_Tyr PF07714.17 PRP84041.1 - 5.3e-16 58.7 0.0 3.6e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP84041.1 - 1.9e-14 54.0 1.7 3.5e-14 53.2 1.7 1.5 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 PRP84041.1 - 1.6e-08 34.3 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PH_9 PF15410.6 PRP84041.1 - 0.017 15.5 1.3 6.6 7.1 0.6 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 PRP84041.1 - 0.017 15.5 4.5 0.061 13.8 4.5 2.0 2 1 0 2 2 2 0 Pleckstrin homology domain MFS_1 PF07690.16 PRP84042.1 - 7.4e-34 117.2 45.3 3.1e-27 95.4 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP84042.1 - 5.5e-20 71.6 13.8 2.3e-16 59.7 1.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Cu_amine_oxid PF01179.20 PRP84043.1 - 5.1e-160 532.9 0.2 6.2e-160 532.6 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 PRP84043.1 - 1.4e-15 57.5 0.0 3.5e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 PRP84043.1 - 6e-13 48.8 0.7 1.8e-11 44.1 0.1 2.7 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain zinc_ribbon_15 PF17032.5 PRP84044.1 - 8.1e-07 29.7 0.4 8.1e-07 29.7 0.4 1.7 2 1 1 3 3 3 1 zinc-ribbon family DUF3797 PF12677.7 PRP84044.1 - 0.064 13.2 1.6 7.2 6.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) HscB_4_cys PF18256.1 PRP84044.1 - 2.9 7.8 7.1 2.6 7.9 1.5 2.5 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif PTEN_C2 PF10409.9 PRP84045.1 - 9.1e-09 35.2 0.1 1.6e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 PRP84045.1 - 5.4e-07 29.5 0.0 1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP84045.1 - 2.8e-05 23.8 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP84045.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PRP84045.1 - 0.063 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate RRM_1 PF00076.22 PRP84045.1 - 0.097 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4139 PF13598.6 PRP84046.1 - 1.6e-55 188.1 2.3 1.6e-55 188.1 2.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 PRP84046.1 - 6e-21 74.7 0.5 6e-21 74.7 0.5 3.1 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Leu_Phe_trans PF03588.14 PRP84046.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase PKcGMP_CC PF16808.5 PRP84046.1 - 0.5 10.3 4.6 0.52 10.2 0.7 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pro-rich PF15240.6 PRP84047.1 - 0.0045 17.3 24.3 0.0063 16.8 24.3 1.3 1 0 0 1 1 1 1 Proline-rich Ribonuclease_3 PF00636.26 PRP84048.1 - 5.2e-10 39.9 0.8 2.5e-08 34.5 0.8 2.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 PRP84048.1 - 0.00012 22.2 0.0 0.00027 21.1 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease-III-like Pkinase_Tyr PF07714.17 PRP84049.1 - 7e-81 271.3 0.0 1.7e-63 214.4 0.0 3.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP84049.1 - 2.2e-62 210.8 0.0 6.1e-53 179.9 0.0 3.3 2 1 0 2 2 2 2 Protein kinase domain TPD PF14811.6 PRP84049.1 - 1.5e-42 144.7 0.7 1e-41 142.0 0.7 2.2 1 1 0 1 1 1 1 Protein of unknown function TPD sequence-motif LRR_8 PF13855.6 PRP84049.1 - 1e-26 92.4 38.9 9.6e-07 28.5 0.6 7.8 3 2 5 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 PRP84049.1 - 1.5e-14 53.9 44.8 6.5e-06 26.4 0.3 9.4 4 4 5 10 10 10 5 Leucine Rich repeats (2 copies) SH2 PF00017.24 PRP84049.1 - 1.2e-10 41.3 0.0 3e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 SH2 domain GPS PF01825.21 PRP84049.1 - 1.3e-09 38.5 0.7 2.9e-09 37.3 0.7 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP84049.1 - 1.1e-05 25.3 32.7 0.25 12.1 0.2 11.2 12 1 0 12 12 11 2 Leucine Rich Repeat APH PF01636.23 PRP84049.1 - 0.0024 17.8 0.1 0.0047 16.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP84049.1 - 0.0032 16.5 0.2 0.012 14.6 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Cbl_N2 PF02761.14 PRP84049.1 - 0.014 16.1 0.1 0.064 14.0 0.0 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Ank_2 PF12796.7 PRP84050.1 - 0.00039 21.0 2.2 0.68 10.6 0.5 3.7 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84050.1 - 0.033 14.8 3.1 23 5.7 0.0 4.6 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84050.1 - 0.15 12.7 7.4 6.7 7.6 0.2 5.0 5 1 1 6 6 6 0 Ankyrin repeat Fur_reg_FbpA PF13076.6 PRP84050.1 - 0.17 11.6 0.1 8.3 6.2 0.0 2.8 2 1 0 2 2 2 0 Fur-regulated basic protein A Ufd2P_core PF10408.9 PRP84051.1 - 1.1e-98 331.5 0.7 1.9e-98 330.7 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin elongating factor core SNF2_N PF00176.23 PRP84051.1 - 8.7e-48 162.8 0.6 1.9e-47 161.7 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain E1-E2_ATPase PF00122.20 PRP84051.1 - 2.2e-45 154.4 4.4 4.9e-44 150.0 0.3 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PRP84051.1 - 3.9e-40 137.5 5.7 1.1e-38 132.8 4.2 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus UQ_con PF00179.26 PRP84051.1 - 2.6e-27 95.2 0.0 1.4e-26 92.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Hydrolase PF00702.26 PRP84051.1 - 7.6e-18 65.6 0.0 4.1e-14 53.4 0.0 3.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP84051.1 - 1.7e-16 60.1 0.4 1.5e-11 44.2 0.1 2.6 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PRP84051.1 - 2.8e-15 55.7 0.1 8.1e-15 54.3 0.1 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Helicase_C PF00271.31 PRP84051.1 - 1e-13 51.6 0.0 3.2e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hydrolase_3 PF08282.12 PRP84051.1 - 0.0011 18.7 1.2 0.0011 18.7 1.2 3.9 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase PV-1 PF06637.11 PRP84051.1 - 0.021 13.7 1.5 0.048 12.5 0.0 2.3 2 0 0 2 2 2 0 PV-1 protein (PLVAP) EXS PF03124.14 PRP84051.1 - 0.096 12.0 2.9 0.34 10.2 0.0 2.5 3 0 0 3 3 3 0 EXS family CENP-N PF05238.13 PRP84051.1 - 0.36 10.1 6.6 1.1 8.5 6.6 1.8 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Ac76 PF05814.11 PRP84051.1 - 1.8 8.6 4.2 8.5 6.5 4.2 2.1 1 0 0 1 1 1 0 Orf76 (Ac76) Vma12 PF11712.8 PRP84051.1 - 4.6 7.3 6.7 0.5 10.4 0.0 2.8 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase F-box-like PF12937.7 PRP84053.1 - 0.036 13.9 2.6 0.04 13.8 1.2 1.8 2 0 0 2 2 2 0 F-box-like NAC PF01849.18 PRP84054.1 - 7.7e-21 73.8 0.3 1.5e-20 72.9 0.3 1.5 1 0 0 1 1 1 1 NAC domain DUF4776 PF16003.5 PRP84054.1 - 0.28 10.1 5.0 0.45 9.5 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) adh_short_C2 PF13561.6 PRP84055.1 - 1.1e-53 182.2 0.0 1.3e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP84055.1 - 1.4e-40 138.8 0.0 1.9e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP84055.1 - 6.4e-09 36.0 0.1 8.2e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP84055.1 - 0.00036 20.1 0.3 0.0023 17.4 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP84055.1 - 0.067 12.6 0.1 0.088 12.2 0.1 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 PRP84055.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ank_4 PF13637.6 PRP84055.1 - 0.17 12.5 0.6 0.43 11.2 0.0 2.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) UDPG_MGDP_dh_N PF03721.14 PRP84055.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MBOAT_2 PF13813.6 PRP84056.1 - 1.3e-14 54.2 5.7 3.8e-14 52.7 5.7 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family zf-MYND PF01753.18 PRP84057.1 - 2e-10 40.6 12.6 2e-10 40.6 12.6 2.2 2 0 0 2 2 2 1 MYND finger Arfaptin PF06456.13 PRP84057.1 - 4.4e-05 23.2 0.6 0.018 14.6 0.7 2.5 2 0 0 2 2 2 2 Arfaptin-like domain zf-C6H2 PF15801.5 PRP84057.1 - 1.1 9.6 9.2 22 5.4 10.1 2.8 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Ank_2 PF12796.7 PRP84058.1 - 2.5e-35 120.9 1.4 7.7e-14 52.0 0.1 4.3 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84058.1 - 1.1e-26 92.8 2.0 8.9e-06 26.2 0.2 6.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84058.1 - 1.4e-21 74.3 4.5 0.047 14.3 0.2 9.0 8 1 1 9 9 9 5 Ankyrin repeat Ank PF00023.30 PRP84058.1 - 1.2e-17 63.4 5.4 0.00084 19.7 0.0 7.4 2 2 5 7 7 7 4 Ankyrin repeat PLAC8 PF04749.17 PRP84058.1 - 5.4e-16 59.4 13.1 5.4e-16 59.4 13.1 2.8 2 1 0 2 2 2 1 PLAC8 family Ank_5 PF13857.6 PRP84058.1 - 1.5e-14 53.8 6.3 0.023 15.0 0.0 8.3 2 1 6 8 8 8 5 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP84058.1 - 8.9e-05 22.3 0.5 8.9e-05 22.3 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP84058.1 - 0.21 11.5 3.0 1.2 9.1 3.0 2.3 1 1 0 1 1 1 0 F-box domain AAA_5 PF07728.14 PRP84059.1 - 5.8e-127 418.3 6.0 4.6e-23 81.8 0.0 10.9 11 0 0 11 11 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 PRP84059.1 - 7.8e-35 119.3 8.0 6.5e-11 42.4 0.2 7.0 6 0 0 6 6 6 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 PRP84059.1 - 6.3e-32 109.8 6.3 2.4e-31 108.0 0.1 4.1 4 0 0 4 4 3 1 Midasin AAA lid domain AAA_7 PF12775.7 PRP84059.1 - 1.2e-28 99.9 4.2 4.9e-06 26.2 0.1 6.7 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_3 PF07726.11 PRP84059.1 - 1.2e-26 93.1 0.0 2.7e-08 33.8 0.0 7.9 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 PRP84059.1 - 1.4e-25 90.2 2.5 0.0017 18.8 0.0 8.5 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP84059.1 - 9.3e-24 84.7 4.4 0.0013 19.1 0.0 8.5 7 1 0 7 7 7 6 AAA ATPase domain Dynein_heavy PF03028.15 PRP84059.1 - 2.3e-22 79.3 0.0 0.00067 19.7 0.0 8.2 8 0 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 PRP84059.1 - 2.2e-20 73.1 0.1 0.0013 18.5 0.0 6.7 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_22 PF13401.6 PRP84059.1 - 7e-17 62.0 4.2 0.0049 17.1 0.0 8.9 9 0 0 9 9 7 3 AAA domain AAA_6 PF12774.7 PRP84059.1 - 4.9e-16 58.6 0.1 0.023 13.7 0.1 7.8 8 0 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region Sigma54_activ_2 PF14532.6 PRP84059.1 - 3.7e-15 56.2 0.2 0.00041 20.5 0.0 6.7 7 0 0 7 7 6 2 Sigma-54 interaction domain TsaE PF02367.17 PRP84059.1 - 5.8e-14 52.2 3.7 0.034 14.2 0.0 6.7 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 PRP84059.1 - 1.6e-13 50.8 1.5 0.005 16.9 0.0 8.2 9 0 0 9 9 7 3 AAA domain AAA_30 PF13604.6 PRP84059.1 - 1.3e-12 47.9 0.0 0.29 10.8 0.0 7.4 7 1 0 7 7 7 3 AAA domain RuvB_N PF05496.12 PRP84059.1 - 1.7e-12 47.4 4.8 0.01 15.6 0.0 7.9 8 0 0 8 8 8 2 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 PRP84059.1 - 4.4e-12 45.6 2.3 0.062 12.4 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein ABC_tran PF00005.27 PRP84059.1 - 5.6e-11 43.1 22.0 0.028 14.9 0.1 8.7 9 0 0 9 9 7 4 ABC transporter Mg_chelatase PF01078.21 PRP84059.1 - 6.7e-11 42.0 1.3 5.6 6.3 0.0 8.9 10 0 0 10 10 9 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 PRP84059.1 - 5.1e-10 39.5 5.6 1.5 8.7 0.0 7.2 6 0 0 6 6 6 2 RsgA GTPase AAA_29 PF13555.6 PRP84059.1 - 3.3e-08 33.2 2.2 6.5 6.6 0.0 6.6 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_19 PF13245.6 PRP84059.1 - 3.6e-08 33.9 8.3 2.2 8.6 0.0 6.9 6 1 0 6 6 6 1 AAA domain VWA PF00092.28 PRP84059.1 - 1.3e-07 32.0 0.2 5.8e-07 29.9 0.2 2.2 1 0 0 1 1 1 1 von Willebrand factor type A domain IstB_IS21 PF01695.17 PRP84059.1 - 1e-06 28.6 1.0 7.1 6.3 0.0 6.5 7 0 0 7 7 6 0 IstB-like ATP binding protein AAA_18 PF13238.6 PRP84059.1 - 1.6e-06 28.7 26.8 4.2 7.9 0.0 9.8 10 0 0 10 10 6 0 AAA domain AAA_33 PF13671.6 PRP84059.1 - 1.7e-06 28.2 1.2 8.8 6.5 0.0 6.7 7 0 0 7 7 5 0 AAA domain NACHT PF05729.12 PRP84059.1 - 5.4e-06 26.4 11.9 3.4 7.6 0.1 7.5 7 0 0 7 7 7 1 NACHT domain AAA_25 PF13481.6 PRP84059.1 - 6.5e-06 25.9 2.2 5.7 6.5 0.0 6.3 6 0 0 6 6 6 0 AAA domain RNA_helicase PF00910.22 PRP84059.1 - 8.6e-06 26.1 10.2 0.35 11.3 0.0 7.2 8 0 0 8 8 6 1 RNA helicase SRP54 PF00448.22 PRP84059.1 - 0.00016 21.3 4.2 2.3 7.8 0.1 5.0 5 0 0 5 5 5 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 PRP84059.1 - 0.00033 20.4 4.4 0.71 9.6 0.1 4.6 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 PRP84059.1 - 0.00043 19.7 4.1 2.9 7.3 0.0 5.8 6 0 0 6 6 6 1 Bacterial TniB protein VWA_2 PF13519.6 PRP84059.1 - 0.0011 19.6 1.2 0.0079 16.8 0.2 3.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Roc PF08477.13 PRP84059.1 - 0.002 18.3 8.1 37 4.6 0.0 7.0 7 0 0 7 7 7 0 Ras of Complex, Roc, domain of DAPkinase DIRP PF06584.13 PRP84059.1 - 0.008 16.3 0.7 0.22 11.7 0.1 3.6 2 0 0 2 2 2 1 DIRP CbiA PF01656.23 PRP84059.1 - 0.0083 16.2 0.0 30 4.7 0.2 5.4 5 1 1 6 6 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 PRP84059.1 - 0.0092 15.5 0.3 20 4.5 0.0 4.3 4 0 0 4 4 4 0 PhoH-like protein NTPase_1 PF03266.15 PRP84059.1 - 0.015 15.2 11.3 28 4.6 0.1 6.5 7 0 0 7 7 6 0 NTPase CPT PF07931.12 PRP84059.1 - 0.024 14.5 2.5 26 4.6 0.0 5.8 7 1 0 7 7 4 0 Chloramphenicol phosphotransferase-like protein AAA_8 PF12780.7 PRP84059.1 - 0.03 13.6 10.3 7.4 5.8 0.0 6.3 7 0 0 7 7 6 0 P-loop containing dynein motor region D4 Cytidylate_kin PF02224.18 PRP84059.1 - 0.032 14.0 0.0 36 4.0 0.0 4.5 4 0 0 4 4 4 0 Cytidylate kinase ATP-synt_ab PF00006.25 PRP84059.1 - 0.12 12.1 0.0 5.1 6.7 0.0 3.4 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 PRP84059.1 - 0.79 9.3 10.9 21 4.6 0.1 6.0 7 0 0 7 7 7 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 PRP84059.1 - 1.6 8.5 15.1 13 5.4 0.0 6.0 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein CLU PF13236.6 PRP84060.1 - 1.1e-52 179.1 0.0 2.5e-52 177.9 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP84060.1 - 1.3e-08 35.1 2.4 2.6e-08 34.1 0.2 2.4 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 Pkinase PF00069.25 PRP84061.1 - 5.3e-25 88.3 0.0 8.9e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84061.1 - 2.9e-24 85.8 0.1 4.9e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP84061.1 - 6.1e-10 39.5 6.8 2.2e-09 37.7 6.8 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Zn_clus PF00172.18 PRP84062.1 - 0.11 12.6 10.7 0.27 11.4 10.7 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.23 PRP84063.1 - 1.9e-20 73.0 1.1 4.5e-20 71.8 1.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PRP84063.1 - 7.6e-12 45.2 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like RTA1 PF04479.13 PRP84064.1 - 1.2e-40 139.4 14.4 2.3e-40 138.4 9.2 2.0 1 1 1 2 2 2 2 RTA1 like protein DUF4173 PF13777.6 PRP84064.1 - 0.0021 17.5 8.6 0.16 11.4 4.7 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4173) DUF2157 PF09925.9 PRP84064.1 - 0.044 13.6 7.1 0.055 13.3 0.5 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.6 PRP84064.1 - 1.4 8.6 14.4 0.31 10.7 4.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) FixP_N PF14715.6 PRP84064.1 - 2.8 7.8 0.0 2.8 7.8 0.0 3.3 4 0 0 4 4 4 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF5542 PF17696.1 PRP84066.1 - 0.011 15.8 0.7 0.018 15.2 0.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5542) PolC_DP2 PF03833.13 PRP84069.1 - 0.26 9.1 0.8 0.33 8.8 0.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PocR PF10114.9 PRP84069.1 - 0.42 10.4 2.1 0.78 9.5 2.1 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR DUF2619 PF10942.8 PRP84070.1 - 0.03 14.4 0.1 0.05 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2619) Frizzled PF01534.17 PRP84070.1 - 0.041 12.9 0.1 0.049 12.7 0.1 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region WD40 PF00400.32 PRP84071.1 - 4.2e-11 43.2 14.2 1.3e-05 25.8 0.1 4.8 5 1 0 5 5 5 3 WD domain, G-beta repeat Mucin15 PF15672.5 PRP84072.1 - 0.25 10.8 0.1 0.32 10.4 0.1 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 DUF2470 PF10615.9 PRP84073.1 - 5.4e-21 75.0 0.1 9.2e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 PRP84073.1 - 0.048 14.0 0.1 0.082 13.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) MORN PF02493.20 PRP84074.1 - 2.9e-33 111.8 42.4 5.6e-08 32.2 1.7 7.3 7 0 0 7 7 7 7 MORN repeat DUF3048_C PF17479.2 PRP84074.1 - 0.18 12.2 13.4 1.8 9.0 1.6 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain G10 PF01125.17 PRP84075.1 - 1.7e-65 219.2 7.4 2e-65 219.0 7.4 1.0 1 0 0 1 1 1 1 G10 protein Ank_4 PF13637.6 PRP84076.1 - 4.1e-66 218.5 14.6 8.5e-13 48.5 0.1 7.3 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP84076.1 - 9.5e-65 215.2 15.7 1.9e-17 63.6 0.9 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 PRP84076.1 - 5.4e-47 156.3 15.4 1.1e-06 28.8 0.0 8.7 8 0 0 8 8 8 8 Ankyrin repeat RabGAP-TBC PF00566.18 PRP84076.1 - 3e-45 154.5 0.7 6.1e-45 153.5 0.7 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_5 PF13857.6 PRP84076.1 - 1.1e-43 146.7 5.7 2.7e-08 33.9 0.0 7.1 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84076.1 - 4.2e-40 131.2 6.0 0.00059 20.1 0.0 8.9 8 0 0 8 8 8 8 Ankyrin repeat Homeodomain PF00046.29 PRP84076.1 - 1.2e-13 50.7 2.7 2.7e-13 49.5 2.7 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP84076.1 - 0.16 11.9 0.9 0.37 10.7 0.9 1.6 1 0 0 1 1 1 0 Homeobox KN domain PFK PF00365.20 PRP84077.1 - 4.1e-186 617.0 0.5 6.9e-104 347.1 0.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 PRP84077.1 - 8.3e-06 26.1 0.1 1.7e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast TackOD1 PF18551.1 PRP84077.1 - 0.19 11.4 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Pkinase PF00069.25 PRP84078.1 - 8.3e-64 215.5 0.0 1.5e-63 214.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84078.1 - 3.4e-33 115.0 0.0 5.2e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 PRP84078.1 - 8e-14 51.9 3.9 1.1e-05 25.8 0.2 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PRP84078.1 - 2.3e-13 48.9 2.4 0.0032 17.3 0.0 5.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 PRP84078.1 - 2.3e-10 39.2 9.0 0.0025 17.2 0.0 6.0 7 0 0 7 7 7 4 EF hand Acetyltransf_7 PF13508.7 PRP84078.1 - 6.6e-10 39.3 0.0 1.7e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EF-hand_8 PF13833.6 PRP84078.1 - 7e-08 32.2 0.0 1.1 9.2 0.0 4.5 3 1 0 3 3 3 3 EF-hand domain pair Acetyltransf_1 PF00583.25 PRP84078.1 - 1e-07 32.2 0.2 9.6e-07 29.1 0.1 2.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP84078.1 - 1.2e-07 31.7 0.2 2.8e-05 24.1 0.0 2.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Kinase-like PF14531.6 PRP84078.1 - 4.5e-06 26.2 0.5 5.3e-05 22.7 0.1 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 PRP84078.1 - 0.00042 20.3 0.1 0.00099 19.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_5 PF13202.6 PRP84078.1 - 0.00047 19.5 1.1 0.26 10.9 0.1 4.7 5 0 0 5 5 5 1 EF hand RIO1 PF01163.22 PRP84078.1 - 0.0056 16.3 0.1 0.016 14.8 0.1 1.8 1 0 0 1 1 1 1 RIO1 family Acetyltransf_CG PF14542.6 PRP84078.1 - 0.028 14.6 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-TRAF PF02176.18 PRP84079.1 - 0.011 16.4 2.7 0.011 16.4 2.7 2.8 2 1 0 2 2 2 0 TRAF-type zinc finger Pox_M2 PF04887.12 PRP84079.1 - 0.079 12.4 0.1 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Poxvirus M2 protein zf-TRAF_2 PF15965.5 PRP84079.1 - 7.2 7.2 13.7 0.28 11.7 7.4 2.0 2 0 0 2 2 2 0 TRAF-like zinc-finger Pkinase PF00069.25 PRP84081.1 - 6.5e-58 196.2 0.1 3.3e-57 193.9 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84081.1 - 1.1e-26 93.7 0.1 3.1e-18 66.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.11 PRP84081.1 - 0.00014 21.0 0.1 0.00025 20.2 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 PRP84081.1 - 0.00048 19.2 8.2 0.0014 17.7 8.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PRP84081.1 - 0.00051 19.5 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP84081.1 - 0.0025 17.2 0.2 0.0042 16.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP84081.1 - 1.7 7.3 9.8 0.96 8.1 1.3 2.4 2 1 0 2 2 2 0 Fungal protein kinase RTA1 PF04479.13 PRP84083.1 - 7.7e-66 221.6 4.9 7.7e-66 221.6 4.9 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF5487 PF17589.2 PRP84083.1 - 0.02 15.1 0.1 0.049 13.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5487) DUF373 PF04123.13 PRP84083.1 - 0.44 9.9 6.8 0.37 10.2 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4131 PF13567.6 PRP84083.1 - 4.4 6.9 6.6 4.9 6.8 1.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RhoGEF PF00621.20 PRP84084.1 - 4.6e-54 183.4 0.0 6.3e-30 104.8 0.0 2.6 2 0 0 2 2 2 2 RhoGEF domain PH_13 PF16652.5 PRP84084.1 - 2.8e-11 43.5 0.3 1.1e-05 25.3 0.0 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 PRP84084.1 - 1.3e-08 35.3 0.3 0.016 15.7 0.0 3.7 3 0 0 3 3 3 2 PH domain CH PF00307.31 PRP84084.1 - 4.3e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain PH_2 PF08458.10 PRP84084.1 - 0.0016 18.8 0.5 0.53 10.7 0.0 3.4 3 0 0 3 3 3 1 Plant pleckstrin homology-like region PH_9 PF15410.6 PRP84084.1 - 0.0067 16.8 0.2 3.4 8.1 0.0 3.8 3 1 0 3 3 3 1 Pleckstrin homology domain DUF393 PF04134.12 PRP84084.1 - 0.0097 17.2 0.0 0.047 15.0 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 PH_6 PF15406.6 PRP84084.1 - 0.14 12.4 0.1 31 4.9 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain DHR10 PF18595.1 PRP84084.1 - 0.3 11.2 3.5 0.14 12.2 0.2 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Glyco_transf_15 PF01793.16 PRP84085.1 - 4.3e-52 177.4 0.0 7.4e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L19e PF01280.20 PRP84085.1 - 1.3e-11 44.7 0.4 2.6e-11 43.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e Ets PF00178.22 PRP84085.1 - 0.041 14.4 0.8 0.13 12.8 0.8 1.9 1 0 0 1 1 1 0 Ets-domain LPG_synthase_TM PF03706.13 PRP84085.1 - 0.46 10.0 2.6 0.66 9.5 2.6 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Ribosomal_L17 PF01196.19 PRP84086.1 - 2.8e-28 98.7 0.1 3.6e-28 98.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Tautomerase_2 PF14552.6 PRP84086.1 - 0.067 13.3 0.1 10 6.3 0.0 2.2 1 1 1 2 2 2 0 Tautomerase enzyme Filament PF00038.21 PRP84087.1 - 0.0021 17.7 2.2 0.0031 17.2 2.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein LPD39 PF18858.1 PRP84087.1 - 0.014 15.5 0.6 0.022 14.9 0.6 1.2 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 Peptidase_S8 PF00082.22 PRP84088.1 - 5.6e-36 124.3 9.7 1.8e-35 122.7 9.7 1.7 1 1 0 1 1 1 1 Subtilase family Myb_DNA-bind_7 PF15963.5 PRP84090.1 - 2.2e-17 62.7 2.7 4.2e-17 61.8 0.0 2.3 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 PRP84090.1 - 0.0025 18.0 0.0 0.009 16.2 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain RtcR PF06956.11 PRP84090.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase Asp_Arg_Hydrox PF05118.15 PRP84091.1 - 2.4e-42 144.5 0.0 3.7e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Pkinase_Tyr PF07714.17 PRP84093.1 - 6.2e-33 114.2 0.0 8.7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84093.1 - 7.7e-27 94.3 0.0 1.3e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP84093.1 - 1.4e-07 31.9 6.7 1.4e-07 31.9 6.7 2.5 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_8 PF13855.6 PRP84093.1 - 7.2e-07 28.9 10.3 0.00024 20.8 2.2 5.5 4 1 2 6 6 6 3 Leucine rich repeat LRR_6 PF13516.6 PRP84093.1 - 2.3e-06 27.2 0.7 2.5 8.4 0.0 5.6 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 PRP84093.1 - 0.00012 22.4 8.8 0.00067 20.0 0.2 4.8 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP84093.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_1 PF00560.33 PRP84093.1 - 0.0084 16.5 6.2 16 6.5 0.0 6.3 7 0 0 7 7 5 1 Leucine Rich Repeat Mitofilin PF09731.9 PRP84093.1 - 2.5 6.8 6.1 3.8 6.2 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF572 PF04502.13 PRP84093.1 - 3.3 7.2 11.6 6.8 6.2 11.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 PRP84093.1 - 5 5.9 13.6 9.5 4.9 13.6 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain HTH_10 PF04967.12 PRP84095.1 - 0.056 13.3 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain CRM1_C PF08767.11 PRP84096.1 - 1.3e-120 402.4 2.8 1.3e-120 402.4 2.8 2.6 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 PRP84096.1 - 8e-34 116.8 3.1 8e-34 116.8 3.1 4.5 4 2 1 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 PRP84096.1 - 1.3e-32 111.2 0.1 4.7e-32 109.4 0.1 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 PRP84096.1 - 5.3e-27 93.7 1.3 5.3e-27 93.7 1.3 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 PRP84096.1 - 7e-20 70.3 0.4 1.5e-19 69.2 0.4 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 PRP84096.1 - 9.4e-13 47.9 0.6 9.4e-13 47.9 0.6 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain ANTH PF07651.16 PRP84096.1 - 0.0092 15.0 0.1 0.025 13.5 0.1 1.7 1 0 0 1 1 1 1 ANTH domain V-ATPase_H_C PF11698.8 PRP84096.1 - 0.02 15.0 2.8 1 9.5 0.0 4.1 4 0 0 4 4 4 0 V-ATPase subunit H Prolamin_like PF05617.11 PRP84096.1 - 0.068 13.4 0.1 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 Prolamin-like HEAT PF02985.22 PRP84096.1 - 0.077 13.3 0.0 7 7.2 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat RasGEF PF00617.19 PRP84097.1 - 5.1e-30 105.0 0.9 8.1e-30 104.3 0.1 1.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP84097.1 - 2.7e-12 46.8 0.2 7.1e-12 45.5 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DEP PF00610.21 PRP84097.1 - 1.9e-07 31.0 0.3 6.3e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase_Tyr PF07714.17 PRP84098.1 - 1.6e-78 263.6 0.1 4.8e-78 262.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84098.1 - 5e-56 190.0 0.0 7.9e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP84098.1 - 5.7e-45 150.9 95.0 1.8e-07 30.8 0.0 14.6 8 4 7 17 17 17 14 Leucine rich repeat LRR_4 PF12799.7 PRP84098.1 - 1.9e-37 126.6 107.6 0.00033 21.0 0.9 18.0 12 4 8 22 22 21 17 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP84098.1 - 0.00025 21.2 84.1 3.5 8.5 0.2 23.2 25 3 0 25 25 23 2 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP84098.1 - 0.00034 19.5 0.0 0.00034 19.5 0.0 1.5 2 0 0 2 2 1 1 Fungal protein kinase Kdo PF06293.14 PRP84098.1 - 0.0019 17.6 0.2 0.004 16.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP84098.1 - 0.0047 15.9 0.2 0.012 14.6 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 PRP84098.1 - 0.18 11.4 0.0 0.6 9.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family LRR_6 PF13516.6 PRP84098.1 - 0.37 11.0 83.1 1.3 9.3 0.2 19.7 23 0 0 23 23 23 0 Leucine Rich repeat LRR_5 PF13306.6 PRP84098.1 - 1.8 8.5 7.1 4.6 7.2 0.3 3.8 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Ras PF00071.22 PRP84099.1 - 1.5e-65 219.8 0.4 1.8e-65 219.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP84099.1 - 3.3e-36 124.1 0.2 5.2e-36 123.5 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP84099.1 - 1.6e-16 60.3 0.1 2.1e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP84099.1 - 3.6e-06 27.0 0.3 0.058 13.3 0.1 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP84099.1 - 2.8e-05 24.2 0.0 6.6e-05 23.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP84099.1 - 4.2e-05 23.0 0.1 5.6e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP84099.1 - 4.2e-05 23.2 0.3 0.0001 21.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PRP84099.1 - 5.9e-05 22.6 0.1 8.7e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 PRP84099.1 - 0.0023 18.3 0.0 0.071 13.5 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 PRP84099.1 - 0.017 14.6 0.1 0.087 12.3 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 PRP84099.1 - 0.048 14.0 0.0 0.081 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 PRP84099.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PRP84099.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PRP84099.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 PRP84099.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 PRP84099.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 PRP84099.1 - 0.13 12.0 0.1 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 PRP84099.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein A_deaminase PF00962.22 PRP84100.1 - 7.3e-180 597.4 1.8 8.2e-97 324.4 0.0 2.9 3 0 0 3 3 3 2 Adenosine/AMP deaminase C1_4 PF07975.12 PRP84100.1 - 0.13 12.5 0.2 0.41 10.9 0.2 1.8 1 0 0 1 1 1 0 TFIIH C1-like domain Csm1_N PF18504.1 PRP84100.1 - 2.2 8.7 8.1 15 6.0 0.1 3.8 2 1 1 3 3 3 0 Csm1 N-terminal domain Tox-ODYAM1 PF15642.6 PRP84101.1 - 0.0014 17.7 3.3 0.0019 17.2 3.3 1.2 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus DUF3332 PF11810.8 PRP84101.1 - 0.2 11.3 0.8 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) Lung_7-TM_R PF06814.13 PRP84102.1 - 5.9e-12 45.4 7.3 1e-11 44.7 7.3 1.4 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 PRP84102.1 - 4.4e-05 23.0 11.1 5.5e-05 22.7 9.1 2.1 1 1 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain PTR2 PF00854.21 PRP84104.1 - 5.7e-18 64.9 20.4 8.8e-14 51.1 8.8 2.6 1 1 1 2 2 2 2 POT family 3Beta_HSD PF01073.19 PRP84105.1 - 2.2e-72 243.4 0.0 2.6e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PRP84105.1 - 3.8e-27 95.3 0.0 5e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP84105.1 - 5.3e-19 68.8 0.0 4.2e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PRP84105.1 - 4.4e-17 62.1 0.0 6.3e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PRP84105.1 - 9.3e-13 47.9 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PRP84105.1 - 1.2e-10 41.0 0.1 3.4e-10 39.5 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 PRP84105.1 - 6.3e-08 32.7 0.0 9.7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP84105.1 - 2.6e-06 27.4 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 PRP84105.1 - 4.6e-06 26.2 0.0 7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.6 PRP84105.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.13 PRP84105.1 - 0.059 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Methyltransf_25 PF13649.6 PRP84105.1 - 0.064 14.0 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DnaJ_CXXCXGXG PF00684.19 PRP84109.1 - 0.051 13.9 21.0 2.5 8.5 13.4 2.9 1 1 1 2 2 2 0 DnaJ central domain RasGEF PF00617.19 PRP84110.1 - 7.7e-32 110.9 0.2 1.4e-31 110.0 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain Kelch_6 PF13964.6 PRP84110.1 - 1e-27 95.4 6.3 3.3e-07 30.3 0.1 7.2 7 0 0 7 7 7 5 Kelch motif Kelch_5 PF13854.6 PRP84110.1 - 6.1e-27 93.1 9.6 3.4e-05 23.7 0.0 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_1 PF01344.25 PRP84110.1 - 4.5e-23 80.6 4.8 5.6e-06 25.9 0.1 6.5 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 PRP84110.1 - 4.9e-22 77.7 5.3 9.9e-09 35.3 0.0 6.9 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP84110.1 - 4.9e-19 67.5 5.2 6.2e-08 32.3 0.1 6.7 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 PRP84110.1 - 5.2e-19 68.0 9.4 7.7e-05 22.6 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain RasGEF_N PF00618.20 PRP84110.1 - 2.8e-15 56.4 0.2 8e-15 55.0 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Inhibitor_I9 PF05922.16 PRP84110.1 - 9.9e-05 22.9 0.1 9.9e-05 22.9 0.1 2.4 3 0 0 3 3 3 1 Peptidase inhibitor I9 SAP PF02037.27 PRP84112.1 - 3.1e-09 36.3 3.4 5.3e-08 32.4 0.6 2.3 2 0 0 2 2 2 2 SAP domain PHM7_cyt PF14703.6 PRP84112.1 - 0.023 15.0 1.7 0.034 14.4 1.7 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Peptidase_C1_2 PF03051.15 PRP84112.1 - 0.027 13.2 0.4 0.036 12.8 0.4 1.1 1 0 0 1 1 1 0 Peptidase C1-like family FAM76 PF16046.5 PRP84112.1 - 0.59 9.4 4.9 0.93 8.8 4.9 1.3 1 0 0 1 1 1 0 FAM76 protein Rad60-SLD PF11976.8 PRP84114.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PRP84114.1 - 0.0053 16.5 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RabGAP-TBC PF00566.18 PRP84115.1 - 1.3e-55 188.3 1.1 1.8e-55 188.0 1.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ROK PF00480.20 PRP84116.1 - 0.049 13.1 0.1 0.07 12.6 0.1 1.1 1 0 0 1 1 1 0 ROK family WES_acyltransf PF03007.16 PRP84117.1 - 4.3e-17 62.7 0.0 6.6e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1298 PF06974.13 PRP84117.1 - 7e-11 42.3 0.0 2.6e-10 40.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1298) Glyco_hydro_76 PF03663.14 PRP84118.1 - 1e-20 74.6 9.5 4.2e-17 62.7 2.9 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 PAN_1 PF00024.26 PRP84118.1 - 0.0032 17.4 0.2 0.0094 15.9 0.2 1.7 1 0 0 1 1 1 1 PAN domain Cofilin_ADF PF00241.20 PRP84120.1 - 5e-15 55.4 0.0 6.1e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FAD_binding_1 PF00667.20 PRP84120.1 - 0.095 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain SIR2 PF02146.17 PRP84121.1 - 8.6e-18 64.9 0.0 1.9e-17 63.7 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Pkinase PF00069.25 PRP84122.1 - 3.1e-43 148.0 0.0 3.5e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84122.1 - 7.1e-21 74.7 0.0 7.9e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP84122.1 - 9.7e-07 28.9 0.1 3.2e-06 27.3 0.1 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP84122.1 - 2.7e-06 26.9 0.2 4.6e-06 26.1 0.1 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP84122.1 - 4.5e-06 25.7 0.0 8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 PRP84122.1 - 0.023 14.3 1.3 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 PRP84122.1 - 0.03 13.9 0.4 0.3 10.6 0.1 2.3 1 1 1 2 2 2 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PRP84122.1 - 0.11 11.5 0.1 0.92 8.4 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Actin PF00022.19 PRP84123.1 - 6.8e-38 130.3 0.0 1e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 Actin WD40 PF00400.32 PRP84124.1 - 1.5e-13 50.9 15.1 0.0054 17.6 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84124.1 - 1.9e-06 28.0 0.4 0.33 11.3 0.1 5.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP84124.1 - 0.00044 20.2 1.3 0.19 11.6 0.2 2.8 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ank_2 PF12796.7 PRP84125.1 - 9.3e-78 256.9 0.9 2.1e-13 50.7 0.0 8.3 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84125.1 - 1.1e-46 156.5 16.6 5.1e-05 23.7 0.0 10.9 6 2 0 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84125.1 - 7.4e-45 145.8 11.0 0.057 14.0 0.0 18.2 19 0 0 19 19 19 13 Ankyrin repeat Ank PF00023.30 PRP84125.1 - 3.8e-39 131.5 31.6 0.24 11.9 0.1 18.4 15 4 4 19 19 19 13 Ankyrin repeat Ank_5 PF13857.6 PRP84125.1 - 4e-30 103.5 6.2 0.14 12.6 0.0 16.3 5 4 13 18 18 18 10 Ankyrin repeats (many copies) VWA_3_C PF18571.1 PRP84125.1 - 1.8e-06 27.7 1.3 21 5.1 0.0 9.4 14 0 0 14 14 14 1 von Willebrand factor type A C-terminal domain DUF4246 PF14033.6 PRP84125.1 - 0.011 14.9 12.4 18 4.3 0.0 9.8 5 5 9 14 14 14 0 Protein of unknown function (DUF4246) tRNA-synt_1 PF00133.22 PRP84126.1 - 2.1e-200 667.0 0.7 1.8e-197 657.3 0.7 3.5 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PRP84126.1 - 1.7e-38 132.0 0.0 1.7e-38 132.0 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PRP84126.1 - 9.4e-13 47.7 4.5 2.3e-05 23.3 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 PRP84126.1 - 4.1e-05 23.2 8.0 0.0033 16.9 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 PRP84126.1 - 0.0092 15.4 0.0 0.0092 15.4 0.0 3.7 5 0 0 5 5 5 1 tRNA synthetases class I (C) catalytic domain Hist_deacetyl PF00850.19 PRP84127.1 - 9e-79 265.1 0.4 1.2e-78 264.7 0.4 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF3784 PF12650.7 PRP84128.1 - 0.00046 20.3 3.1 0.036 14.2 0.0 3.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3784) Acetyltransf_7 PF13508.7 PRP84129.1 - 9.3e-06 26.0 0.1 2.2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP84129.1 - 3.2e-05 23.8 0.0 6.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PRP84129.1 - 5.5e-05 23.3 0.0 0.00013 22.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP84129.1 - 0.0026 17.7 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP84129.1 - 0.019 15.2 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 PRP84129.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Amidinotransf PF02274.17 PRP84130.1 - 2.7e-108 362.1 1.7 8.5e-54 182.9 0.9 3.0 2 1 0 2 2 2 2 Amidinotransferase PAD_porph PF04371.15 PRP84130.1 - 0.0013 18.1 0.1 0.003 16.9 0.1 1.6 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase F-box-like PF12937.7 PRP84133.1 - 9e-07 28.7 0.0 2.3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP84133.1 - 0.0013 18.6 1.2 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain SMI1_KNR4 PF09346.10 PRP84133.1 - 0.0045 17.4 0.0 0.0083 16.5 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) F-box_4 PF15966.5 PRP84133.1 - 0.062 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box ubiquitin PF00240.23 PRP84134.1 - 1.5e-05 24.6 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family GRDP-like PF07173.12 PRP84134.1 - 0.083 13.5 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like ubiquitin PF00240.23 PRP84136.1 - 1.8e-17 62.8 0.0 3.4e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP84136.1 - 1.4e-08 34.5 0.0 6.5e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 PRP84136.1 - 0.0019 18.1 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain GRDP-like PF07173.12 PRP84136.1 - 0.013 16.1 0.1 0.18 12.4 0.0 2.4 2 1 1 3 3 3 0 Glycine-rich domain-containing protein-like DUF2407 PF10302.9 PRP84136.1 - 0.013 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP84136.1 - 0.099 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF1295 PF06966.12 PRP84137.1 - 2.3e-44 151.7 0.9 1.2e-42 146.0 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 PRP84137.1 - 0.00019 21.8 0.0 0.0011 19.3 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 PRP84137.1 - 0.0053 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 PRP84137.1 - 0.015 15.7 0.2 0.11 13.0 0.0 2.5 3 0 0 3 3 3 0 Phospholipid methyltransferase Syntaxin PF00804.25 PRP84138.1 - 5e-23 81.8 12.1 5e-23 81.8 12.1 2.5 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.19 PRP84138.1 - 1.2e-08 34.8 0.5 1.2e-08 34.8 0.5 1.9 2 0 0 2 2 2 1 SNARE domain DUF4655 PF15548.6 PRP84138.1 - 0.012 14.6 0.2 0.016 14.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) MCPsignal PF00015.21 PRP84138.1 - 0.031 14.1 5.9 0.23 11.2 1.9 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3040 PF11239.8 PRP84138.1 - 0.1 12.9 0.9 2.2 8.6 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) PCRF PF03462.18 PRP84138.1 - 2.2 8.1 11.6 0.65 9.8 2.7 2.9 1 1 2 3 3 3 0 PCRF domain Glyco_hydro_31 PF01055.26 PRP84139.1 - 3.8e-77 260.3 0.5 5.5e-77 259.8 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 MFS_1 PF07690.16 PRP84139.1 - 8.9e-40 136.7 43.7 8.9e-40 136.7 43.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gal_mutarotas_2 PF13802.6 PRP84139.1 - 9.3e-13 48.3 0.7 2.7e-12 46.8 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 PRP84139.1 - 4.9e-09 36.3 0.0 2.6e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Sugar_tr PF00083.24 PRP84139.1 - 2.8e-07 29.8 9.8 2.8e-07 29.8 9.8 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter PIG-P PF08510.12 PRP84140.1 - 0.37 10.7 3.2 8.5 6.3 0.1 2.7 2 0 0 2 2 2 0 PIG-P DUF5123 PF17161.4 PRP84140.1 - 7 7.8 15.2 0.63 11.1 0.2 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF5123) Peptidase_M15_4 PF13539.6 PRP84141.1 - 0.014 15.9 0.3 5.6 7.6 0.0 2.2 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase GHD PF17834.1 PRP84141.1 - 0.015 15.3 0.2 6.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase Retinin_C PF04527.12 PRP84141.1 - 2 8.7 4.6 6.8 7.0 0.5 2.2 2 0 0 2 2 2 0 Drosophila Retinin like protein TP_methylase PF00590.20 PRP84142.1 - 3e-26 92.7 0.0 5.3e-26 91.9 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_S13_N PF08069.12 PRP84143.1 - 1.6e-29 101.7 0.5 1.6e-29 101.7 0.5 2.2 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain HA PF03457.14 PRP84143.1 - 9.5e-14 51.5 0.3 9.5e-14 51.5 0.3 2.0 2 0 0 2 2 2 1 Helicase associated domain Ribosomal_S15 PF00312.22 PRP84143.1 - 6.7e-13 48.7 0.3 1.7e-12 47.4 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 YflT PF11181.8 PRP84143.1 - 0.18 12.3 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT Auxin_canalis PF05703.11 PRP84143.1 - 0.32 10.9 1.5 0.61 10.0 1.5 1.4 1 0 0 1 1 1 0 Auxin canalisation Nucleo_P87 PF07267.11 PRP84143.1 - 2.7 6.7 5.3 3.8 6.3 5.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TTc_toxin_rep PF18807.1 PRP84144.1 - 0.0075 16.1 0.3 0.013 15.3 0.3 1.3 1 0 0 1 1 1 1 Tripartite Tc toxins repeat Abhydrolase_1 PF00561.20 PRP84145.1 - 2.9e-16 59.9 0.1 1.1e-09 38.3 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP84145.1 - 1e-11 45.9 0.0 1.3e-11 45.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP84145.1 - 1e-09 38.1 0.1 5.6e-09 35.6 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 PRP84145.1 - 0.00012 21.7 0.0 0.0033 17.0 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PRP84145.1 - 0.0017 17.8 0.1 0.0038 16.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Thioesterase PF00975.20 PRP84145.1 - 0.003 17.7 0.0 0.0056 16.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain BAAT_C PF08840.11 PRP84145.1 - 0.0068 16.3 0.1 0.35 10.8 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 PRP84145.1 - 0.07 12.8 0.0 0.47 10.1 0.0 2.2 3 0 0 3 3 3 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 PRP84145.1 - 0.1 12.5 0.3 3.1 7.6 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold TK PF00265.18 PRP84146.1 - 5e-63 212.2 0.1 5.9e-63 211.9 0.1 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 PRP84146.1 - 0.00056 19.9 0.0 0.00081 19.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 PRP84146.1 - 0.17 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RhoGAP PF00620.27 PRP84147.1 - 7.8e-36 123.2 0.0 1.7e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FERM_f0 PF16511.5 PRP84147.1 - 0.15 12.4 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 N-terminal or F0 domain of Talin-head FERM PSCyt3 PF07627.11 PRP84147.1 - 0.16 12.2 3.2 3.8 7.8 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF1588) D123 PF07065.14 PRP84149.1 - 1.6e-11 43.9 0.0 1.2e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 D123 Dioxygenase_C PF00775.21 PRP84150.1 - 4.7e-09 35.9 0.0 7.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase SYS1 PF09801.9 PRP84151.1 - 3.1e-45 153.8 4.1 3.6e-45 153.7 4.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CLU PF13236.6 PRP84152.1 - 1.1e-54 185.7 0.0 2.1e-54 184.7 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria PH PF00169.29 PRP84152.1 - 7.7e-19 68.1 0.1 2.7e-18 66.4 0.1 2.1 1 0 0 1 1 1 1 PH domain DEP PF00610.21 PRP84152.1 - 1.6e-12 47.3 0.2 7.5e-12 45.1 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TPR_17 PF13431.6 PRP84152.1 - 3.6e-09 36.4 0.0 0.00038 20.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat PH_11 PF15413.6 PRP84152.1 - 5.6e-07 29.9 0.6 6.9e-06 26.4 0.6 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PRP84152.1 - 1.8e-06 28.1 0.5 1.3e-05 25.4 0.0 2.7 3 0 0 3 3 1 1 Pleckstrin homology domain Pex24p PF06398.11 PRP84152.1 - 3.5e-06 26.3 12.3 7.8e-06 25.1 12.3 1.6 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin eIF3_p135 PF12807.7 PRP84152.1 - 1.4e-05 25.2 2.7 3e-05 24.1 0.1 2.6 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 PH_3 PF14593.6 PRP84152.1 - 0.00079 19.5 0.1 0.0032 17.5 0.1 2.0 1 0 0 1 1 1 1 PH domain TPR_8 PF13181.6 PRP84152.1 - 0.0011 19.0 1.1 1.1 9.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PH_6 PF15406.6 PRP84152.1 - 0.0011 19.2 0.0 0.0061 16.8 0.0 2.3 1 0 0 1 1 1 1 Pleckstrin homology domain TPR_14 PF13428.6 PRP84152.1 - 0.0013 19.4 0.2 0.72 10.8 0.1 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP84152.1 - 0.013 15.6 1.7 19 5.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP84152.1 - 0.033 14.7 0.1 2.8 8.5 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP84152.1 - 0.055 13.8 1.4 9 6.7 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat PH_2 PF08458.10 PRP84152.1 - 0.16 12.4 0.7 1 9.8 0.0 2.7 3 0 0 3 3 2 0 Plant pleckstrin homology-like region DUF4464 PF14713.6 PRP84153.1 - 1.1e-82 276.9 0.8 1.4e-82 276.6 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) DUF1765 PF08578.10 PRP84154.1 - 5.2e-08 33.4 3.5 5.2e-08 33.4 3.5 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1765) Pkinase_Tyr PF07714.17 PRP84155.1 - 9.4e-78 261.1 0.0 5.4e-77 258.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP84155.1 - 5e-67 221.5 135.3 1.7e-08 34.1 8.4 19.1 8 5 14 23 23 23 21 Leucine rich repeat Pkinase PF00069.25 PRP84155.1 - 8.1e-55 186.0 0.0 1.3e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP84155.1 - 7e-48 159.8 144.4 1.1e-05 25.6 5.6 23.7 11 6 10 25 25 25 19 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP84155.1 - 6e-05 23.1 107.5 2.8 8.8 0.2 29.7 30 5 1 31 31 31 2 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP84155.1 - 0.00022 20.1 0.0 0.00041 19.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP84155.1 - 0.0023 17.3 0.3 0.0048 16.3 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP84155.1 - 0.0054 15.7 0.2 0.01 14.8 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain LRRNT_2 PF08263.12 PRP84155.1 - 0.12 12.7 5.8 0.3 11.4 5.8 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain RIO1 PF01163.22 PRP84155.1 - 0.18 11.4 0.0 0.56 9.8 0.0 1.7 2 0 0 2 2 2 0 RIO1 family RhoGAP PF00620.27 PRP84156.1 - 7.9e-33 113.4 0.0 1.5e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain IMS_C PF11799.8 PRP84156.1 - 0.088 13.5 0.2 1.9 9.2 0.0 2.4 2 0 0 2 2 2 0 impB/mucB/samB family C-terminal domain eIF-1a PF01176.19 PRP84157.1 - 1.5e-12 47.2 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Nop14 PF04147.12 PRP84157.1 - 1.1 7.4 12.3 1.2 7.2 12.3 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 PRP84157.1 - 3.4 5.7 15.6 3.8 5.5 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 PRP84157.1 - 9.8 6.6 10.4 19 5.7 10.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_A22B PF04258.13 PRP84158.1 - 3e-90 302.6 9.8 3.8e-90 302.3 9.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase Presenilin PF01080.17 PRP84158.1 - 0.01 14.7 2.7 0.01 14.7 2.7 1.7 2 0 0 2 2 2 1 Presenilin DUF655 PF04919.12 PRP84158.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) LRR_6 PF13516.6 PRP84160.1 - 1.6e-59 192.9 67.2 6.7e-06 25.8 0.1 17.0 17 0 0 17 17 17 10 Leucine Rich repeat U-box PF04564.15 PRP84160.1 - 6.7e-19 67.8 0.0 3.7e-17 62.3 0.0 2.8 2 0 0 2 2 2 1 U-box domain SAM_1 PF00536.30 PRP84160.1 - 3.2e-09 37.1 2.3 0.00011 22.5 0.1 3.5 2 1 1 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP84160.1 - 6.3e-08 32.6 0.7 0.002 18.2 0.1 3.2 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) LRR_4 PF12799.7 PRP84160.1 - 9.5e-07 29.1 35.1 0.31 11.5 1.3 9.8 4 2 8 12 12 12 7 Leucine Rich repeats (2 copies) zf-Nse PF11789.8 PRP84160.1 - 0.00017 21.3 0.0 0.0012 18.6 0.0 2.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit LRR_8 PF13855.6 PRP84160.1 - 0.00032 20.4 47.5 0.96 9.3 3.0 10.5 5 3 3 9 9 9 3 Leucine rich repeat DUF1494 PF07379.11 PRP84160.1 - 0.001 18.9 0.6 6.4 6.6 0.0 4.8 2 2 1 4 4 4 1 Protein of unknown function (DUF1494) TP6A_N PF04406.14 PRP84160.1 - 0.05 13.6 5.1 7.4 6.6 0.0 5.2 5 0 0 5 5 4 0 Type IIB DNA topoisomerase LEH PF07858.12 PRP84160.1 - 0.23 11.6 8.7 20 5.3 0.1 5.1 2 2 3 6 6 6 0 Limonene-1,2-epoxide hydrolase catalytic domain DUF2161 PF09929.9 PRP84160.1 - 0.98 9.6 21.2 8.4 6.5 0.0 6.4 6 0 0 6 6 6 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) PilN PF05137.13 PRP84160.1 - 1 9.6 11.8 11 6.2 0.2 4.6 2 1 1 3 3 3 0 Fimbrial assembly protein (PilN) TAL_effector PF03377.13 PRP84160.1 - 4.1 7.8 21.5 86 3.6 0.0 9.1 11 0 0 11 11 10 0 TAL effector repeat UPF0020 PF01170.18 PRP84161.1 - 6.1e-22 78.3 0.0 1.7e-21 76.8 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 PRP84161.1 - 4.3e-06 26.4 0.0 0.067 12.6 0.0 2.9 2 1 1 3 3 3 2 RRNA methyltransferase AviRa Methyltransf_25 PF13649.6 PRP84161.1 - 0.0044 17.7 0.0 0.019 15.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP84161.1 - 0.028 14.2 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 PRP84161.1 - 0.22 10.9 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ACOX PF01756.19 PRP84162.1 - 3.4e-34 118.0 0.1 6.9e-23 81.1 0.1 2.3 2 0 0 2 2 2 2 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PRP84162.1 - 3e-17 62.6 0.0 5.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 PRP84162.1 - 5.2e-12 46.4 2.3 1.4e-11 45.0 2.3 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal TAP42 PF04177.12 PRP84162.1 - 0.02 14.0 2.5 0.023 13.8 0.2 2.0 2 0 0 2 2 2 0 TAP42-like family Chromo PF00385.24 PRP84164.1 - 1.7e-13 50.2 0.0 2.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP84164.1 - 0.042 14.0 0.5 0.067 13.4 0.5 1.5 1 1 0 1 1 1 0 Polycomb-like MTF2 factor 2 Head-tail_con PF12236.8 PRP84167.1 - 0.16 10.4 0.0 0.2 10.1 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein DNA_pol_phi PF04931.13 PRP84168.1 - 0.12 10.5 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Complex1_LYR PF05347.15 PRP84169.1 - 7e-11 42.0 0.0 8.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PRP84169.1 - 0.0032 18.2 0.0 0.0037 18.0 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 PRP84169.1 - 0.022 15.3 0.0 0.026 15.1 0.0 1.1 1 0 0 1 1 1 0 Complex1_LYR-like ETC_C1_NDUFA5 PF04716.14 PRP84169.1 - 0.042 13.7 0.8 0.24 11.2 0.8 2.0 1 1 0 1 1 1 0 ETC complex I subunit conserved region Propeptide_C25 PF08126.11 PRP84169.1 - 0.05 12.7 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Propeptide_C25 AAA PF00004.29 PRP84170.1 - 7.3e-42 142.9 0.0 2.8e-41 141.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP84170.1 - 2.8e-08 33.4 0.0 6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PRP84170.1 - 1.6e-05 24.9 0.1 7.8e-05 22.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP84170.1 - 2.5e-05 24.6 0.0 0.0062 16.8 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 PRP84170.1 - 3.1e-05 24.4 0.1 0.00052 20.4 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PRP84170.1 - 8.6e-05 22.3 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 PRP84170.1 - 0.00057 19.1 0.0 0.0014 17.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 PRP84170.1 - 0.00059 20.0 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 PRP84170.1 - 0.0026 18.3 0.0 0.009 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PRP84170.1 - 0.0032 17.7 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PRP84170.1 - 0.0034 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 PRP84170.1 - 0.0076 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 PRP84170.1 - 0.012 15.6 0.0 0.71 9.7 0.0 2.6 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 PRP84170.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 PRP84170.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 PRP84170.1 - 0.014 14.9 0.0 0.041 13.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 PRP84170.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 PRP84170.1 - 0.026 14.3 0.1 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 PRP84170.1 - 0.049 13.5 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 PRP84170.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PRP84170.1 - 0.092 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 PRP84170.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 PRP84170.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF1556 PF07590.11 PRP84171.1 - 0.093 13.1 0.1 0.093 13.1 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1556) TPR_14 PF13428.6 PRP84172.1 - 2.4e-14 52.8 15.1 0.091 13.6 1.7 9.0 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP84172.1 - 1.2e-12 48.1 1.1 1.5 9.4 0.1 8.0 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 PRP84172.1 - 4.6e-08 33.6 3.1 0.15 12.7 0.0 5.9 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP84172.1 - 4.3e-06 26.4 16.6 0.4 10.9 0.1 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP84172.1 - 7.5e-06 26.0 0.0 0.074 13.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP84172.1 - 1.1e-05 25.2 1.1 1.2 9.5 0.0 5.5 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP84172.1 - 0.0085 15.9 6.9 19 5.3 0.5 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP84172.1 - 0.067 13.5 13.3 21 5.5 0.1 6.4 9 1 0 9 9 9 0 Tetratricopeptide repeat MIT PF04212.18 PRP84172.1 - 0.21 11.7 4.1 18 5.5 0.0 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 PRP84172.1 - 0.23 12.2 9.8 1.6e+02 3.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF4398 PF14346.6 PRP84172.1 - 5.8 7.6 9.3 26 5.5 0.5 4.4 5 0 0 5 5 4 0 Domain of unknown function (DUF4398) DAP_B PF07930.12 PRP84173.1 - 0.095 12.7 0.8 0.11 12.4 0.8 1.1 1 0 0 1 1 1 0 D-aminopeptidase, domain B zf-C4H2 PF10146.9 PRP84173.1 - 1.1 9.5 4.5 1.4 9.2 4.5 1.3 1 1 0 1 1 1 0 Zinc finger-containing protein LRR_9 PF14580.6 PRP84174.1 - 1.3e-16 60.6 14.9 2.2e-16 59.9 6.4 3.4 1 1 2 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 PRP84174.1 - 2.9e-13 49.8 21.1 4.6e-07 30.1 1.4 4.6 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP84174.1 - 1e-10 41.2 17.0 3.5e-06 26.7 2.0 3.9 1 1 2 3 3 3 3 Leucine rich repeat PsbU PF06514.11 PRP84174.1 - 0.11 12.5 0.2 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) Ribosomal_L9_N PF01281.19 PRP84175.1 - 3.5e-15 55.3 0.1 6e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 PRP84175.1 - 0.012 16.0 0.0 0.48 10.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain Histone PF00125.24 PRP84176.1 - 1.5e-05 25.4 0.0 0.0083 16.5 0.0 2.7 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 Ank_4 PF13637.6 PRP84176.1 - 0.02 15.5 0.0 0.063 13.9 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) F-box PF00646.33 PRP84176.1 - 0.037 13.9 0.0 0.22 11.4 0.0 2.3 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.7 PRP84176.1 - 0.15 12.6 0.0 0.7 10.5 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) SH3_1 PF00018.28 PRP84177.1 - 3.6e-18 64.9 1.8 3.5e-08 32.9 0.2 3.3 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 PRP84177.1 - 1e-14 53.9 0.1 7.5e-09 35.1 0.1 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 PRP84177.1 - 8.7e-13 47.9 6.1 1.4e-06 28.0 0.1 3.5 3 1 0 3 3 3 2 Variant SH3 domain FCH PF00611.23 PRP84177.1 - 1.2e-05 25.4 0.5 7.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Imm52 PF15579.6 PRP84177.1 - 0.037 13.9 0.3 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 52 Ank_3 PF13606.6 PRP84177.1 - 0.11 13.1 0.1 21 6.1 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat V_ATPase_I PF01496.19 PRP84177.1 - 1.2 7.0 8.3 1.8 6.4 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNARE PF05739.19 PRP84177.1 - 1.2 9.2 3.2 6.6 6.8 0.2 2.5 2 0 0 2 2 2 0 SNARE domain DUF4407 PF14362.6 PRP84177.1 - 6.6 6.0 8.4 10 5.4 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TBP PF00352.21 PRP84179.1 - 6.5e-63 208.7 0.4 1.2e-30 105.2 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 PRP84179.1 - 0.0062 16.6 0.0 0.48 10.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) Glyco_transf_8C PF08437.10 PRP84179.1 - 0.032 14.3 0.6 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal ORC3_N PF07034.11 PRP84180.1 - 1.7e-22 80.0 11.0 2e-17 63.3 4.5 3.2 2 2 2 4 4 4 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 PRP84180.1 - 1.2e-14 54.5 1.7 1.8e-07 31.3 0.0 3.5 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal Pex2_Pex12 PF04757.14 PRP84180.1 - 0.031 13.9 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region IL2 PF00715.17 PRP84180.1 - 0.042 13.8 0.1 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 Interleukin 2 V-ATPase_G_2 PF16999.5 PRP84182.1 - 0.12 12.8 9.0 0.13 12.7 2.8 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit CRT10 PF08728.10 PRP84182.1 - 0.23 9.6 3.7 0.24 9.5 3.7 1.0 1 0 0 1 1 1 0 CRT10 Neur_chan_memb PF02932.16 PRP84182.1 - 9.1 6.3 7.4 13 5.8 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CBM9_2 PF16011.5 PRP84184.1 - 0.012 15.3 0.1 0.035 13.8 0.1 1.7 1 1 1 2 2 2 0 Carbohydrate-binding family 9 FAD_binding_4 PF01565.23 PRP84185.1 - 3.1e-22 78.8 0.2 4.8e-22 78.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PRP84185.1 - 3.3e-14 52.7 0.3 6.1e-14 51.9 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like TAD2 PF18521.1 PRP84185.1 - 0.2 11.7 1.7 0.84 9.7 1.7 2.0 1 0 0 1 1 1 0 Transactivation domain 2 Pro-kuma_activ PF09286.11 PRP84186.1 - 4.6e-19 69.1 0.1 7.9e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Sporozoite_P67 PF05642.11 PRP84186.1 - 3.3 5.7 10.6 4.4 5.3 10.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RhoGAP PF00620.27 PRP84188.1 - 7.8e-27 94.0 0.0 1.7e-26 92.9 0.0 1.6 1 1 0 1 1 1 1 RhoGAP domain Motile_Sperm PF00635.26 PRP84188.1 - 0.0069 16.2 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 MSP (Major sperm protein) domain MFS_1 PF07690.16 PRP84189.1 - 2.8e-41 141.6 24.8 1.4e-39 136.1 27.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF521 PF04412.13 PRP84189.1 - 0.072 11.8 0.1 0.16 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF521) SNAD2 PF18745.1 PRP84190.1 - 0.13 12.0 1.8 0.59 9.8 1.8 2.0 1 1 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 HIT PF01230.23 PRP84191.1 - 5.1e-28 97.7 0.0 5.9e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PRP84191.1 - 4e-20 72.4 0.0 4.7e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding SH3_2 PF07653.17 PRP84192.1 - 6.1e-22 77.1 0.1 6.3e-09 35.4 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 PRP84192.1 - 3.3e-20 71.7 0.0 4.9e-12 45.5 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 PRP84192.1 - 1e-17 63.5 0.0 1.2e-10 40.8 0.0 3.4 3 0 0 3 3 3 3 SH3 domain MbeD_MobD PF04899.12 PRP84192.1 - 0.047 13.8 1.0 0.28 11.3 1.4 2.1 2 0 0 2 2 2 0 MbeD/MobD like Methyltransf_17 PF12692.7 PRP84192.1 - 0.08 12.9 0.2 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase DUF4618 PF15397.6 PRP84192.1 - 0.43 10.0 6.1 0.16 11.3 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Big_9 PF17963.1 PRP84193.1 - 1.1e-08 35.7 10.2 1.4e-06 28.9 2.3 21.0 20 1 1 21 21 21 3 Bacterial Ig domain Cadherin_5 PF17892.1 PRP84193.1 - 1.8e-08 34.2 13.5 0.0001 22.2 0.7 4.8 4 0 0 4 4 4 2 Cadherin-like domain VCBS PF13517.6 PRP84193.1 - 7.3e-06 26.5 30.4 12 6.5 0.1 14.2 13 0 0 13 13 13 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RRM_1 PF00076.22 PRP84196.1 - 1.1e-17 63.6 0.2 2.2e-17 62.6 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP84196.1 - 1.2e-07 31.3 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 PRP84197.1 - 9e-31 105.5 29.2 1.2e-06 29.1 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 PRP84197.1 - 5.6e-10 38.5 5.8 0.002 16.9 0.0 5.0 3 1 2 5 5 5 3 Nucleoporin Nup120/160 zf-C3HC4_2 PF13923.6 PRP84197.1 - 7.6e-10 38.5 11.3 3.7e-09 36.3 11.1 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP84197.1 - 2.3e-08 33.7 8.8 6.3e-08 32.4 8.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP84197.1 - 3.9e-08 33.0 12.9 3.9e-08 33.0 12.9 2.3 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP84197.1 - 1e-07 31.8 12.3 4.9e-07 29.7 11.7 2.6 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP84197.1 - 6.7e-07 29.2 11.8 1.7e-06 27.9 11.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 PRP84197.1 - 1.2e-06 28.7 11.8 1.2e-06 28.7 11.8 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 PRP84197.1 - 1.1e-05 25.5 13.5 6.5e-05 23.0 13.5 2.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PRP84197.1 - 4.3e-05 23.3 5.8 4.3e-05 23.3 5.8 1.8 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 PRP84197.1 - 5.6e-05 22.9 18.9 0.00014 21.7 13.2 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 Nucleoporin_N PF08801.11 PRP84197.1 - 0.0023 16.8 0.8 0.57 8.9 0.1 3.7 2 1 2 4 4 4 1 Nup133 N terminal like baeRF_family3 PF18845.1 PRP84197.1 - 0.0063 16.8 0.0 6.4 7.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial archaeo-eukaryotic release factor family 3 zf-Nse PF11789.8 PRP84197.1 - 0.0088 15.8 9.1 0.021 14.6 9.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit BBS2_Mid PF14783.6 PRP84197.1 - 0.018 15.1 0.0 17 5.5 0.0 4.0 3 2 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region zf-rbx1 PF12678.7 PRP84197.1 - 0.019 15.2 11.5 0.1 12.9 9.5 3.1 2 1 0 2 2 2 0 RING-H2 zinc finger domain DUF4795 PF16043.5 PRP84197.1 - 0.032 13.9 0.5 0.057 13.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) U-box PF04564.15 PRP84197.1 - 0.033 14.4 0.1 0.033 14.4 0.1 2.5 3 0 0 3 3 3 0 U-box domain zf-RING_4 PF14570.6 PRP84197.1 - 0.15 11.9 11.4 3.9 7.3 11.5 2.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 PRP84197.1 - 0.29 11.0 10.0 1.6 8.7 10.0 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 PRP84197.1 - 0.41 11.1 3.5 8.1 7.0 0.9 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 PRP84197.1 - 1.1 9.4 8.9 0.87 9.7 5.6 2.6 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 PRP84197.1 - 1.2 9.2 8.0 3.6 7.7 8.0 1.9 1 0 0 1 1 1 0 Zinc-finger zf-RING_11 PF17123.5 PRP84197.1 - 2 8.2 13.2 0.34 10.7 8.0 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C2H2_9 PF16293.5 PRP84197.1 - 3 7.8 5.0 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) TRP PF06011.12 PRP84198.1 - 1.6e-13 50.2 31.9 7.5e-11 41.4 22.8 3.0 2 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel Big_9 PF17963.1 PRP84198.1 - 1.1e-07 32.5 22.3 3.4e-06 27.7 1.2 5.5 5 0 0 5 5 5 2 Bacterial Ig domain Cadherin_5 PF17892.1 PRP84198.1 - 6.3e-05 22.9 3.1 0.0001 22.2 0.1 2.8 3 0 0 3 3 3 1 Cadherin-like domain FimH_man-bind PF09160.10 PRP84198.1 - 0.033 13.9 3.0 0.17 11.6 0.6 3.1 3 0 0 3 3 3 0 FimH, mannose binding DUF2157 PF09925.9 PRP84198.1 - 8.3 6.2 10.1 4.7 7.0 5.7 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) SH3_2 PF07653.17 PRP84199.1 - 3.8e-22 77.7 0.1 5.3e-09 35.6 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.6 PRP84199.1 - 2e-20 72.3 0.0 4.2e-12 45.7 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 PRP84199.1 - 6.2e-18 64.1 0.0 1e-10 41.0 0.0 3.4 3 0 0 3 3 3 3 SH3 domain Methyltransf_17 PF12692.7 PRP84199.1 - 0.065 13.2 0.2 0.18 11.8 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase DUF4618 PF15397.6 PRP84199.1 - 0.28 10.6 5.9 0.14 11.6 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) HIT PF01230.23 PRP84200.1 - 9.3e-27 93.6 0.2 2.5e-26 92.3 0.0 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 PRP84200.1 - 5.9e-19 68.6 0.5 2.2e-18 66.8 0.0 2.2 3 0 0 3 3 3 1 Scavenger mRNA decapping enzyme C-term binding F-box-like PF12937.7 PRP84200.1 - 0.031 14.2 0.2 0.083 12.8 0.2 1.8 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 PRP84201.1 - 1.6e-15 56.9 17.6 1.5e-09 37.3 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box PF00646.33 PRP84201.1 - 0.036 13.9 0.8 0.22 11.4 0.8 2.3 1 1 0 1 1 1 0 F-box domain MatP PF06303.12 PRP84203.1 - 0.091 13.3 0.7 16 6.1 0.2 2.8 2 0 0 2 2 2 0 MatP N-terminal domain ABC_tran PF00005.27 PRP84204.1 - 1.4e-42 145.4 0.6 1.1e-22 81.0 0.0 3.5 3 0 0 3 3 2 2 ABC transporter Ank_2 PF12796.7 PRP84204.1 - 3.5e-37 126.8 0.7 2.8e-09 37.4 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) ABC_tran_Xtn PF12848.7 PRP84204.1 - 2.9e-22 78.5 7.2 2.9e-22 78.5 7.2 3.4 3 0 0 3 3 3 1 ABC transporter Ank_4 PF13637.6 PRP84204.1 - 4.8e-21 74.8 5.4 5.8e-06 26.8 0.2 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP84204.1 - 7.7e-17 60.9 3.3 0.14 12.6 0.0 7.3 7 0 0 7 7 6 4 Ankyrin repeat AAA_21 PF13304.6 PRP84204.1 - 2e-14 54.1 7.3 0.001 18.9 0.1 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Ank_3 PF13606.6 PRP84204.1 - 5.7e-11 41.6 0.2 7 7.6 0.0 7.1 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 PRP84204.1 - 1.3e-09 38.1 1.8 0.22 11.9 0.1 7.0 1 1 6 7 7 7 1 Ankyrin repeats (many copies) RsgA_GTPase PF03193.16 PRP84204.1 - 1.5e-06 28.2 0.1 0.0061 16.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 PRP84204.1 - 3e-06 27.3 0.0 0.087 12.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 PRP84204.1 - 3.6e-06 27.5 2.8 0.046 14.1 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 PRP84204.1 - 7.2e-06 25.9 0.2 0.026 14.3 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PRP84204.1 - 8.9e-06 26.3 0.5 0.077 13.5 0.0 4.2 4 1 1 5 5 2 1 AAA domain AAA_29 PF13555.6 PRP84204.1 - 9.2e-06 25.3 0.1 0.041 13.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PRP84204.1 - 1.6e-05 25.2 0.2 0.14 12.5 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 PRP84204.1 - 1.6e-05 24.8 5.6 0.083 12.6 1.4 3.9 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 PRP84204.1 - 2.3e-05 24.9 0.1 0.37 11.2 0.0 3.8 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 PRP84204.1 - 2.4e-05 24.4 0.0 0.1 12.7 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 PRP84204.1 - 5.9e-05 23.3 0.1 0.44 10.8 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 PRP84204.1 - 0.00011 22.2 0.1 1.2 9.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PRP84204.1 - 0.00043 19.8 0.1 0.096 12.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 PRP84204.1 - 0.00046 20.5 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 1 RNA helicase DAP3 PF10236.9 PRP84204.1 - 0.00055 19.2 0.1 0.22 10.6 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 SMC_N PF02463.19 PRP84204.1 - 0.00066 19.2 2.6 1.9 7.8 0.0 4.1 4 1 0 5 5 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 PRP84204.1 - 0.0011 18.6 0.0 0.58 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 PRP84204.1 - 0.0013 18.7 0.3 1.2 9.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 PRP84204.1 - 0.0018 18.3 0.1 0.98 9.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP84204.1 - 0.0029 17.4 0.0 2.9 7.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PRP84204.1 - 0.003 17.8 0.0 0.3 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 PRP84204.1 - 0.0048 16.1 0.0 0.37 9.9 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.14 PRP84204.1 - 0.0057 15.9 0.8 1.8 7.7 0.0 3.4 4 0 0 4 4 3 1 KAP family P-loop domain Pox_A32 PF04665.12 PRP84204.1 - 0.018 14.5 0.1 4.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein Ras PF00071.22 PRP84204.1 - 0.019 14.5 2.0 4.5 6.9 0.1 3.0 3 0 0 3 3 3 0 Ras family AAA_33 PF13671.6 PRP84204.1 - 0.02 15.0 7.8 0.37 10.9 0.0 4.2 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 PRP84204.1 - 0.032 14.6 0.0 17 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 PRP84204.1 - 0.034 13.2 0.1 0.42 9.7 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain DUF815 PF05673.13 PRP84204.1 - 0.035 13.3 0.1 1.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 PRP84204.1 - 0.071 12.9 0.0 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein BiPBP_C PF06832.12 PRP84204.1 - 0.076 13.1 0.6 2.9 8.0 0.1 3.3 1 1 1 3 3 3 0 Penicillin-Binding Protein C-terminus Family DUF87 PF01935.17 PRP84204.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.9 5 0 0 5 5 4 0 Helicase HerA, central domain SbcCD_C PF13558.6 PRP84204.1 - 0.2 11.9 0.6 2.6 8.4 0.0 3.0 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.15 PRP84204.1 - 0.29 11.0 9.8 1.4 8.8 0.0 4.6 6 0 0 6 6 5 0 NTPase AAA_23 PF13476.6 PRP84204.1 - 0.71 10.3 20.5 1.1 9.8 0.0 4.4 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 PRP84204.1 - 1.4 8.9 4.4 12 5.9 0.1 3.8 4 0 0 4 4 4 0 Dynamin family MeaB PF03308.16 PRP84204.1 - 5.6 5.9 9.4 4.5 6.2 0.0 3.3 4 0 0 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB WD40 PF00400.32 PRP84206.1 - 0.13 13.2 0.0 0.3 12.1 0.0 1.7 1 1 0 1 1 1 0 WD domain, G-beta repeat PI-PLC-X PF00388.19 PRP84208.1 - 3.2e-62 208.4 0.0 1.3e-61 206.5 0.0 2.0 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 PRP84208.1 - 6.8e-35 119.9 0.0 2e-34 118.4 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 PRP84208.1 - 1.7e-16 60.4 0.0 3.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 PRP84208.1 - 1.2e-10 41.7 0.3 4.7e-10 39.8 0.2 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 PRP84208.1 - 2.9e-10 39.0 3.9 0.00011 21.4 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PRP84208.1 - 7.7e-10 39.1 4.6 6.8e-09 36.1 0.7 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP84208.1 - 1.6e-07 30.7 8.5 0.0067 16.3 0.2 3.9 4 0 0 4 4 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP84208.1 - 8.6e-07 28.2 3.4 0.0052 16.2 0.4 2.9 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 PRP84208.1 - 0.00021 21.1 0.8 0.00054 19.8 0.8 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 PRP84208.1 - 0.00032 20.5 2.6 0.0018 18.1 0.7 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 PRP84208.1 - 0.0007 19.5 1.1 0.75 9.8 0.1 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Fe_hyd_lg_C PF02906.14 PRP84208.1 - 0.035 13.8 1.1 0.065 12.9 1.1 1.4 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain SAM_3 PF18016.1 PRP84208.1 - 0.095 12.5 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Amino_oxidase PF01593.24 PRP84209.1 - 5.6e-67 227.0 0.0 8.2e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP84209.1 - 7.2e-13 48.6 0.4 2.5e-12 46.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP84209.1 - 6.9e-11 42.3 0.0 1.3e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PRP84209.1 - 2.5e-09 36.8 1.8 0.00097 18.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP84209.1 - 2.3e-06 27.0 0.2 3.5e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 PRP84209.1 - 0.00014 21.2 0.7 0.00022 20.6 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 PRP84209.1 - 0.00045 19.5 0.1 0.00079 18.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 PRP84209.1 - 0.00066 18.5 0.7 0.019 13.7 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 PRP84209.1 - 0.0022 17.3 0.9 0.0051 16.1 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PRP84209.1 - 0.0039 16.6 0.1 0.0053 16.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PRP84209.1 - 0.006 15.7 0.2 0.0098 15.0 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 PRP84209.1 - 0.0076 15.4 0.3 0.03 13.4 0.1 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 PRP84209.1 - 0.011 15.7 0.2 0.19 11.7 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 PRP84209.1 - 0.013 14.7 0.5 0.99 8.5 0.1 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 PRP84209.1 - 0.065 13.8 0.9 0.15 12.7 0.2 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 PRP84209.1 - 0.082 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase Sialidase PF02973.16 PRP84209.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Sialidase, N-terminal domain LppC PF04348.13 PRP84209.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein Adaptin_N PF01602.20 PRP84210.1 - 1.3e-118 396.9 8.2 1.7e-118 396.5 8.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 PRP84210.1 - 6.7e-48 162.7 0.0 1.4e-47 161.6 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 PRP84210.1 - 1e-34 119.1 0.1 2.3e-34 118.0 0.1 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 PRP84210.1 - 5.4e-16 58.8 2.2 3e-06 27.5 0.0 5.3 3 2 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 PRP84210.1 - 2e-14 53.9 3.1 3.5e-08 33.7 0.5 4.3 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP84210.1 - 2.6e-06 27.2 0.6 0.73 10.3 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 PRP84210.1 - 0.17 12.0 1.7 76 3.6 0.0 5.2 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 PRP84210.1 - 1.3 9.9 3.7 92 4.2 0.1 4.2 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat ArfGap PF01412.18 PRP84211.1 - 9.1e-30 103.1 0.0 2.2e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 PRP84211.1 - 7.3e-07 29.7 0.5 4.7e-06 27.1 0.1 2.5 2 0 0 2 2 2 1 PH domain RNA_ligase PF09414.10 PRP84212.1 - 1.2e-20 74.4 0.1 2.8e-20 73.3 0.0 1.6 2 0 0 2 2 2 1 RNA ligase LRR_8 PF13855.6 PRP84213.1 - 2.8e-14 52.6 11.8 0.00028 20.6 0.3 6.3 5 2 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PRP84213.1 - 9.8e-09 35.4 23.2 0.088 13.3 0.9 8.1 7 2 3 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP84213.1 - 5.4e-07 29.3 15.6 7 7.6 0.1 10.4 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP84213.1 - 7.6e-07 28.7 14.2 5 7.4 0.0 9.5 11 0 0 11 11 11 3 Leucine Rich repeat TRP PF06011.12 PRP84213.1 - 6.9e-06 25.0 17.5 1.9e-05 23.6 17.3 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel SPT6_acidic PF14632.6 PRP84213.1 - 0.3 11.7 0.8 0.5 11.0 0.8 1.2 1 0 0 1 1 1 0 Acidic N-terminal SPT6 FAD_binding_3 PF01494.19 PRP84214.1 - 1.5e-20 73.8 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP84214.1 - 1.2e-05 24.7 0.1 0.032 13.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP84214.1 - 1.6e-05 24.7 0.2 0.00019 21.1 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 PRP84214.1 - 0.0023 18.5 0.0 0.16 12.6 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP84214.1 - 0.0045 17.2 0.1 0.013 15.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PRP84214.1 - 0.01 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 PRP84214.1 - 0.069 12.5 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PRP84214.1 - 0.087 12.1 0.1 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DOMON PF03351.17 PRP84216.1 - 5.4e-80 265.7 14.7 6e-24 84.6 0.8 4.4 4 0 0 4 4 4 4 DOMON domain Ferric_reduct PF01794.19 PRP84216.1 - 1.3e-20 73.8 13.2 4.1e-20 72.1 13.2 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 PRP84216.1 - 4.8e-13 49.5 0.0 9.6e-07 29.1 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PRP84216.1 - 1.1e-12 48.0 0.0 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain CDH-cyt PF16010.5 PRP84216.1 - 9.4e-08 31.9 6.3 0.00088 19.0 0.1 3.9 4 0 0 4 4 4 2 Cytochrome domain of cellobiose dehydrogenase NAD_binding_1 PF00175.21 PRP84216.1 - 0.0028 18.3 0.0 0.007 17.0 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PRP84216.1 - 0.006 16.9 0.0 0.038 14.4 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cation_ATPase_C PF00689.21 PRP84217.1 - 2.4e-40 138.2 3.8 2.4e-40 138.2 3.8 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PRP84217.1 - 4.5e-28 98.0 1.2 4.5e-28 98.0 1.2 3.1 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 PRP84217.1 - 1.7e-19 70.9 0.0 5.4e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP84217.1 - 5.7e-18 64.8 0.1 1e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PRP84217.1 - 3.4e-12 45.9 0.0 7.7e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PRP84217.1 - 6.1e-05 22.9 0.1 0.00015 21.6 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3784 PF12650.7 PRP84217.1 - 0.46 10.7 5.9 0.26 11.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) Rotamase PF00639.21 PRP84218.1 - 8.3e-26 90.8 0.2 3e-25 89.0 0.0 2.0 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PRP84218.1 - 1.2e-21 77.4 0.0 2.9e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 PRP84218.1 - 0.00048 20.9 0.0 0.0013 19.6 0.0 1.7 1 0 0 1 1 1 1 PPIC-type PPIASE domain CGGC PF08821.11 PRP84218.1 - 0.74 10.0 4.4 11 6.3 1.4 2.4 1 1 0 2 2 2 0 CGGC domain Kelch_3 PF13415.6 PRP84219.1 - 8.4e-37 124.8 4.9 5.4e-09 36.1 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP84219.1 - 1.3e-36 124.0 3.4 1.4e-06 28.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PRP84219.1 - 3.7e-31 106.4 3.7 2.1e-07 31.0 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PRP84219.1 - 2e-25 88.5 4.9 3.3e-08 33.4 0.0 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 PRP84219.1 - 3.7e-24 84.0 2.6 3e-06 26.7 0.0 6.9 6 1 0 6 6 6 6 Kelch motif DUF4110 PF13422.6 PRP84219.1 - 1.7e-20 72.9 6.6 1.7e-20 72.9 6.6 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.15 PRP84219.1 - 5.3e-20 70.6 3.7 6.5e-05 22.7 0.0 6.5 6 0 0 6 6 6 6 Kelch motif LPD11 PF18824.1 PRP84219.1 - 0.044 13.9 2.2 1.3 9.1 0.3 2.9 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 LpxC PF03331.13 PRP84220.1 - 0.084 12.4 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase MFS_1_like PF12832.7 PRP84221.1 - 1.7e-58 198.4 19.1 2.3e-58 197.9 19.1 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 PRP84221.1 - 2.2e-22 79.5 30.4 2.2e-22 79.5 30.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PRP84221.1 - 6.9e-10 38.5 15.0 9.8e-10 38.0 15.0 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 PRP84221.1 - 7.3e-10 38.2 11.8 1.1e-09 37.6 11.2 1.4 1 1 0 1 1 1 1 LacY proton/sugar symporter Methyltransf_3 PF01596.17 PRP84223.1 - 3e-60 203.0 0.0 3.9e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 PRP84223.1 - 2.6e-12 47.7 0.0 4.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PRP84223.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DHQ_synthase PF01761.20 PRP84224.1 - 5.1e-54 183.2 0.0 7.6e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 PRP84224.1 - 2.5e-12 47.0 0.0 3.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 PRP84224.1 - 1e-05 24.6 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Glyco_hydro_20 PF00728.22 PRP84225.1 - 4.1e-73 246.8 2.4 1.5e-72 244.9 1.3 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 PRP84225.1 - 2.3e-11 44.5 0.2 4.5e-11 43.6 0.2 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 PRP84225.1 - 0.00014 22.7 0.0 0.00026 21.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 VIT PF08487.10 PRP84227.1 - 1.4e-29 102.5 0.0 3.4e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PRP84227.1 - 4.7e-22 78.6 0.0 8.5e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Glyco_hydro_16 PF00722.21 PRP84227.1 - 2.5e-21 75.9 2.4 5.6e-21 74.8 2.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 VIT_2 PF13757.6 PRP84227.1 - 7.5e-13 48.2 0.3 3e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 PRP84227.1 - 2.4e-11 44.2 0.0 6.7e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain PAN_4 PF14295.6 PRP84227.1 - 7.8e-10 38.5 3.6 7.8e-10 38.5 3.6 3.1 3 0 0 3 3 3 1 PAN domain Chitin_bind_1 PF00187.19 PRP84227.1 - 7.7e-08 32.7 23.6 7.7e-08 32.7 23.6 3.1 3 0 0 3 3 3 1 Chitin recognition protein VWA_2 PF13519.6 PRP84227.1 - 9.3e-07 29.5 0.0 5.6e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain PAN_2 PF08276.11 PRP84227.1 - 0.00022 21.3 2.5 0.00022 21.3 2.5 2.7 2 0 0 2 2 2 1 PAN-like domain CobT_C PF11775.8 PRP84227.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain MFS_1 PF07690.16 PRP84229.1 - 3.6e-38 131.4 30.0 5.6e-38 130.8 30.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP84229.1 - 2.7e-34 118.8 12.2 3.4e-34 118.5 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 PRP84229.1 - 1.1e-06 27.5 20.8 0.002 16.8 4.5 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.8 PRP84229.1 - 0.23 10.0 14.1 0.011 14.4 6.2 2.2 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like MFS_1 PF07690.16 PRP84230.1 - 8.5e-41 140.0 39.0 8.9e-40 136.7 34.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP84230.1 - 5.2e-14 52.0 10.8 5.2e-14 52.0 10.8 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 PRP84230.1 - 1.5 7.0 12.3 0.28 9.4 3.5 3.1 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family HAMP PF00672.25 PRP84231.1 - 9.3e-179 579.9 91.5 1.3e-07 31.9 0.2 27.6 25 4 4 29 29 29 23 HAMP domain Response_reg PF00072.24 PRP84231.1 - 6.4e-45 151.9 1.4 3.1e-25 88.5 0.0 3.2 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 PRP84231.1 - 3.9e-30 104.6 0.0 2.5e-29 102.1 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF948 PF06103.11 PRP84231.1 - 2e-20 72.8 213.6 0.2 11.9 2.0 32.2 8 7 15 23 23 23 18 Bacterial protein of unknown function (DUF948) HisKA PF00512.25 PRP84231.1 - 7.1e-20 70.8 0.1 6.5e-19 67.7 0.1 3.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PseudoU_synth_1 PF01416.20 PRP84231.1 - 8e-17 61.7 32.4 42 4.7 0.0 21.1 18 4 1 22 22 22 0 tRNA pseudouridine synthase WXG100 PF06013.12 PRP84231.1 - 2.3e-16 59.8 101.7 0.4 10.9 0.1 22.7 23 1 1 24 24 22 9 Proteins of 100 residues with WXG DUF3829 PF12889.7 PRP84231.1 - 4.1e-13 49.5 50.3 0.73 9.3 0.1 16.7 16 2 0 18 18 17 7 Protein of unknown function (DUF3829) HTH_6 PF01418.17 PRP84231.1 - 5.8e-10 39.0 5.6 29 4.7 0.0 13.6 18 0 0 18 18 18 0 Helix-turn-helix domain, rpiR family ImcF-related_N PF14331.6 PRP84231.1 - 5.3e-06 26.0 7.6 1.2e+02 1.9 0.0 12.0 14 4 4 18 18 18 0 ImcF-related N-terminal domain ApoLp-III PF07464.11 PRP84231.1 - 7.1e-06 26.2 118.3 0.22 11.6 1.0 17.4 5 5 14 19 19 19 7 Apolipophorin-III precursor (apoLp-III) GatB_Yqey PF02637.18 PRP84231.1 - 3.9e-05 23.6 65.1 12 5.8 0.1 18.9 20 0 0 20 20 20 3 GatB domain DUF1843 PF08898.10 PRP84231.1 - 0.00013 22.4 60.9 8 7.1 0.1 19.9 21 1 0 21 21 20 1 Domain of unknown function (DUF1843) Peptidase_M75 PF09375.10 PRP84231.1 - 0.47 9.9 107.7 0.12 11.8 2.0 14.2 1 1 13 15 15 15 0 Imelysin DUF4345 PF14248.6 PRP84231.1 - 1 9.3 27.8 10 6.1 0.1 11.8 13 0 0 13 13 13 0 Domain of unknown function (DUF4345) Usp PF00582.26 PRP84233.1 - 3.5e-07 30.8 1.3 3.7e-07 30.8 0.3 1.6 2 0 0 2 2 2 1 Universal stress protein family HSP90 PF00183.18 PRP84234.1 - 2.7e-190 633.7 18.4 4.3e-190 633.0 18.4 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PRP84234.1 - 2.3e-12 47.4 0.4 5e-12 46.3 0.4 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PRP84234.1 - 2e-11 43.8 0.2 4.6e-11 42.7 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2382 PF09557.10 PRP84234.1 - 0.064 13.5 7.1 0.26 11.6 7.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2382) Peptidase_C1 PF00112.23 PRP84235.1 - 8.9e-47 160.0 6.9 1.5e-46 159.3 6.9 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP84235.1 - 2.5e-09 37.4 3.6 5.9e-09 36.2 3.6 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Propeptide_C1 PF08127.13 PRP84235.1 - 6.1e-07 29.2 0.2 1.4e-06 28.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 PRP84235.1 - 0.00011 21.1 0.8 0.17 10.6 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family PRELI PF04707.14 PRP84236.1 - 7.5e-40 136.3 0.2 8.9e-40 136.1 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family Polysacc_synt_4 PF04669.13 PRP84237.1 - 6.3e-13 48.7 0.7 1.2e-10 41.3 0.1 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis Ammonium_transp PF00909.21 PRP84238.1 - 4.5e-102 341.7 26.7 5.3e-102 341.5 26.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PIG-U PF06728.13 PRP84240.1 - 8.2e-93 311.5 42.5 1.1e-92 311.0 42.5 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 PRP84240.1 - 0.69 9.6 36.8 0.012 15.4 25.1 2.4 1 1 1 2 2 2 0 8TM Microsporidial transmembrane domain NUDIX PF00293.28 PRP84241.1 - 2.3e-05 24.5 0.0 0.00036 20.6 0.0 2.7 1 1 0 1 1 1 1 NUDIX domain DUF2076 PF09849.9 PRP84243.1 - 0.33 11.0 19.5 0.28 11.2 8.9 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) CoA_trans PF01144.23 PRP84244.1 - 4.1e-33 114.6 0.1 4.9e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Coenzyme A transferase Peptidase_S74 PF13884.6 PRP84245.1 - 3e-17 62.7 0.0 1e-16 61.0 0.0 2.0 1 0 0 1 1 1 1 Chaperone of endosialidase DUF3040 PF11239.8 PRP84245.1 - 9.5e-05 22.6 0.2 0.00027 21.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) LptF_LptG PF03739.14 PRP84245.1 - 0.0051 15.7 0.3 0.0079 15.1 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG DUF1640 PF07798.11 PRP84245.1 - 0.023 14.8 0.7 0.4 10.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF2975 PF11188.8 PRP84245.1 - 0.079 12.8 1.9 0.14 12.0 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF4131 PF13567.6 PRP84245.1 - 0.18 11.4 1.6 0.37 10.4 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PRP1_N PF06424.12 PRP84246.1 - 1.6e-49 168.1 2.6 1.6e-49 168.1 2.6 2.0 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 PRP84246.1 - 1.9e-29 99.8 23.5 0.00035 21.2 0.0 15.6 7 5 9 16 16 16 6 Tetratricopeptide repeat TPR_19 PF14559.6 PRP84246.1 - 3e-18 66.1 20.1 0.0045 17.5 1.2 9.8 9 1 2 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 PRP84246.1 - 1.6e-14 53.1 3.1 0.0071 16.7 0.0 10.5 10 1 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP84246.1 - 4e-12 46.6 6.8 2.6e-05 24.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 PRP84246.1 - 2.1e-08 33.8 18.2 0.00045 19.5 3.4 6.5 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP84246.1 - 3.9e-07 29.8 0.0 1.9 8.9 0.1 7.5 8 0 0 8 8 5 1 Tetratricopeptide repeat Suf PF05843.14 PRP84246.1 - 4e-06 27.0 1.6 0.0087 16.1 0.0 4.4 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) DUF3808 PF10300.9 PRP84246.1 - 4.3e-06 25.7 1.2 0.037 12.8 0.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_2 PF07719.17 PRP84246.1 - 2.1e-05 24.3 11.6 1.2 9.5 0.0 8.8 9 0 0 9 9 8 1 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 PRP84246.1 - 0.00018 21.5 1.1 0.41 10.7 0.1 3.8 3 1 0 3 3 3 1 ZNRF-3 Ectodomain TPR_1 PF00515.28 PRP84246.1 - 0.0035 17.1 2.2 4.5 7.3 0.0 4.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 PRP84246.1 - 0.0043 16.8 12.4 0.12 12.1 5.2 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain APG6_N PF17675.1 PRP84246.1 - 0.0063 17.1 12.9 0.45 11.0 0.2 3.4 3 0 0 3 3 3 1 Apg6 coiled-coil region HAT PF02184.16 PRP84246.1 - 0.014 15.3 0.7 26 4.9 0.0 5.3 5 0 0 5 5 5 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.6 PRP84246.1 - 0.037 14.7 18.8 0.42 11.4 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat Babuvirus_MP PF07234.11 PRP84246.1 - 0.038 14.1 1.5 13 5.9 0.1 4.1 2 2 1 4 4 4 0 Movement and RNA silencing protein TPR_11 PF13414.6 PRP84246.1 - 0.072 12.8 4.7 19 5.1 0.0 5.5 5 1 1 6 6 6 0 TPR repeat Wzy_C_2 PF11846.8 PRP84246.1 - 0.11 12.4 0.9 14 5.6 0.5 3.3 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 PRP84246.1 - 0.14 12.4 12.6 3.6 7.9 3.5 5.5 5 1 0 5 5 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 PRP84246.1 - 0.17 12.1 0.9 7.7 6.8 0.2 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain eIF3g PF12353.8 PRP84246.1 - 0.8 10.1 4.3 0.32 11.4 0.3 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Exonuc_VII_L PF02601.15 PRP84246.1 - 0.91 9.0 6.6 8.1 5.9 3.5 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Ribosomal_S26e PF01283.19 PRP84247.1 - 1.8e-51 173.1 8.8 2.1e-51 172.9 8.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 PRP84247.1 - 0.19 12.4 3.6 2.7 8.7 1.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain CxC4 PF18717.1 PRP84247.1 - 0.7 9.7 3.8 2.6 7.9 3.9 1.7 1 1 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases Fer4_2 PF12797.7 PRP84247.1 - 0.71 10.1 5.9 3.9 7.8 2.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain zf-ribbon_3 PF13248.6 PRP84247.1 - 1.5 8.3 5.9 0.85 9.1 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.11 PRP84248.1 - 6.5e-13 48.0 3.3 1.2e-12 47.2 3.3 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) SCA7 PF08313.12 PRP84248.1 - 5.5e-07 29.4 0.1 5.5e-07 29.4 0.1 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain NPR1_interact PF15699.5 PRP84248.1 - 0.022 15.4 5.0 0.038 14.6 5.0 1.4 1 0 0 1 1 1 0 NPR1 interacting zf-CpG_bind_C PF12269.8 PRP84248.1 - 0.47 10.2 8.0 0.48 10.2 0.4 2.7 2 1 1 3 3 3 0 CpG binding protein zinc finger C terminal domain ELFV_dehydrog PF00208.21 PRP84250.1 - 1.1e-61 208.7 1.0 2.1e-57 194.6 0.1 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 PRP84250.1 - 7e-53 178.0 0.0 1.2e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 PRP84250.1 - 0.00073 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 PRP84250.1 - 0.0028 18.1 0.0 0.0058 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 PRP84250.1 - 0.042 13.9 0.9 0.086 12.9 0.9 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.21 PRP84250.1 - 0.059 12.7 0.5 0.13 11.5 0.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Bac_GDH PF05088.12 PRP84250.1 - 0.061 10.8 0.0 0.72 7.3 0.0 2.2 2 1 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase UDPGT PF00201.18 PRP84251.1 - 8.8e-17 61.1 0.1 1.3e-16 60.5 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ER_lumen_recept PF00810.18 PRP84252.1 - 1.2e-53 181.9 9.1 1.2e-53 181.9 9.1 1.9 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 PRP84252.1 - 0.034 13.9 0.6 0.034 13.9 0.6 3.6 4 1 0 4 4 4 0 PQ loop repeat Nipped-B_C PF12830.7 PRP84253.1 - 1.2e-36 126.5 0.1 1.2e-36 126.5 0.1 2.9 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 PRP84253.1 - 1.2e-12 47.9 0.6 2.5e-08 34.1 0.2 4.1 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion PHD PF00628.29 PRP84253.1 - 3.5e-10 39.6 6.0 3.5e-10 39.6 6.0 2.9 2 0 0 2 2 2 1 PHD-finger Cnd1 PF12717.7 PRP84253.1 - 5.3e-07 29.8 4.4 0.16 12.0 0.0 5.8 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP84253.1 - 1e-06 28.4 0.5 0.033 14.4 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat PHD_2 PF13831.6 PRP84253.1 - 0.0006 19.3 3.4 0.0017 17.8 3.4 1.9 1 0 0 1 1 1 1 PHD-finger HEAT_2 PF13646.6 PRP84253.1 - 0.0019 18.5 0.1 6.3 7.3 0.0 4.5 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 PRP84253.1 - 0.002 18.6 0.8 0.93 10.1 0.0 4.3 5 1 0 5 5 5 1 HEAT-like repeat PHD_4 PF16866.5 PRP84253.1 - 2.1 8.5 10.9 0.11 12.6 4.4 2.3 2 0 0 2 2 2 0 PHD-finger Snf7 PF03357.21 PRP84255.1 - 4.8e-46 156.5 11.0 5.7e-46 156.3 11.0 1.0 1 0 0 1 1 1 1 Snf7 DUF1664 PF07889.12 PRP84255.1 - 0.00077 19.5 4.5 0.035 14.1 0.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Prefoldin PF02996.17 PRP84255.1 - 0.016 15.1 6.3 1.2 9.0 0.1 3.2 2 1 0 3 3 3 0 Prefoldin subunit CLZ PF16526.5 PRP84255.1 - 0.025 14.9 3.5 0.89 10.0 0.4 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PID PF00640.23 PRP84255.1 - 0.04 13.9 3.5 0.062 13.3 3.5 1.2 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) NPV_P10 PF05531.12 PRP84255.1 - 0.043 14.3 7.7 4.6 7.8 3.6 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 PRP84255.1 - 0.047 12.6 7.2 0.065 12.1 7.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 PRP84255.1 - 0.082 13.3 7.3 1.4 9.3 6.4 2.1 1 1 1 2 2 2 0 Fez1 YabA PF06156.13 PRP84255.1 - 0.18 12.4 6.9 0.68 10.6 0.7 2.3 1 1 1 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 PRP84255.1 - 0.62 10.5 6.2 11 6.5 0.4 3.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 PRP84255.1 - 1.1 10.0 7.6 13 6.5 0.2 3.5 1 1 1 3 3 3 0 SlyX Fib_alpha PF08702.10 PRP84255.1 - 4.8 7.4 9.5 17 5.6 8.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CorA PF01544.18 PRP84255.1 - 7.4 5.8 9.8 1.7 7.9 1.7 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein IclR PF01614.18 PRP84256.1 - 0.38 10.6 1.1 0.59 10.0 1.1 1.3 1 0 0 1 1 1 0 Bacterial transcriptional regulator Cellulase PF00150.18 PRP84257.1 - 7.2e-17 61.7 7.0 1.1e-16 61.2 7.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 PRP84257.1 - 0.048 13.7 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) adh_short PF00106.25 PRP84258.1 - 2.3e-25 89.2 0.0 3.4e-24 85.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP84258.1 - 1.8e-16 60.4 0.0 1.8e-15 57.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP84258.1 - 8.1e-12 45.4 0.0 1.3e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP84258.1 - 1.8e-05 24.3 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PRP84258.1 - 0.012 14.7 0.1 0.069 12.3 0.1 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TIR-like PF10137.9 PRP84258.1 - 0.017 15.0 0.0 0.042 13.8 0.0 1.7 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain SNF2_N PF00176.23 PRP84259.1 - 3.2e-47 161.0 1.1 5.9e-47 160.1 1.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP84259.1 - 7.8e-15 55.2 0.0 3e-14 53.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP84259.1 - 1.3e-10 41.6 0.1 9.6e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 PRP84259.1 - 1e-07 31.9 0.1 2.9e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 PRP84259.1 - 2.9e-07 30.4 0.0 8.6e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.6 PRP84259.1 - 0.00049 19.1 0.0 0.00098 18.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 NACHT PF05729.12 PRP84259.1 - 0.28 11.1 1.1 14 5.5 0.0 3.1 3 0 0 3 3 3 0 NACHT domain SH3_1 PF00018.28 PRP84260.1 - 8.3e-25 86.2 6.1 1.8e-15 56.3 0.1 3.1 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 PRP84260.1 - 3e-23 81.4 0.8 1.5e-13 50.3 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Glutaminase PF04960.15 PRP84260.1 - 5.3e-22 78.3 0.0 7.7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Glutaminase SH3_2 PF07653.17 PRP84260.1 - 2.6e-20 71.9 0.1 2.9e-11 42.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain CS PF04969.16 PRP84260.1 - 3e-07 31.3 0.0 7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 CS domain SoxD PF04267.12 PRP84261.1 - 0.065 13.4 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family Ribosomal_L36e PF01158.18 PRP84262.1 - 1.8e-33 114.6 5.1 2.3e-33 114.3 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 PRP84262.1 - 0.027 14.5 0.8 0.035 14.2 0.8 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Apc13p PF05839.11 PRP84263.1 - 0.025 14.8 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 Apc13p protein A_deaminase PF00962.22 PRP84264.1 - 6.5e-33 114.4 0.0 7.8e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Aldo_ket_red PF00248.21 PRP84265.1 - 5e-43 147.4 0.0 5.7e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MutL PF13941.6 PRP84265.1 - 0.013 14.1 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 MutL protein SOG2 PF10428.9 PRP84266.1 - 0.6 9.2 51.3 0.015 14.5 17.7 2.2 1 1 1 2 2 2 0 RAM signalling pathway protein Utp14 PF04615.13 PRP84266.1 - 9.4 4.7 14.5 12 4.3 14.5 1.1 1 0 0 1 1 1 0 Utp14 protein Alpha_L_fucos PF01120.17 PRP84268.1 - 8e-111 370.9 12.9 1e-110 370.5 12.9 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 PRP84268.1 - 1.6e-16 60.6 0.4 3.6e-16 59.5 0.4 1.6 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain GHL6 PF14871.6 PRP84268.1 - 0.0053 16.9 0.0 0.012 15.8 0.0 1.6 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Peptidase_C14 PF00656.22 PRP84269.1 - 3.8e-51 174.4 0.0 5.2e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain AIP3 PF03915.13 PRP84270.1 - 2.7e-05 23.5 1.8 2.7e-05 23.5 1.8 3.0 3 1 0 3 3 3 1 Actin interacting protein 3 Rhodanese PF00581.20 PRP84271.1 - 8.5e-09 35.9 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF3663 PF12404.8 PRP84271.1 - 0.13 12.3 0.1 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase DUF4690 PF15756.5 PRP84272.1 - 0.014 15.9 0.2 0.05 14.2 0.2 1.9 1 0 0 1 1 1 0 Small Novel Rich in Cartilage PT PF04886.12 PRP84272.1 - 0.017 14.7 31.8 0.04 13.4 31.8 1.6 1 0 0 1 1 1 0 PT repeat Podoplanin PF05808.11 PRP84272.1 - 0.079 13.1 0.1 0.079 13.1 0.1 2.1 2 0 0 2 2 2 0 Podoplanin Rab15_effector PF15208.6 PRP84272.1 - 0.14 11.4 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 Rab15 effector Leader_CPA1 PF08252.11 PRP84272.1 - 0.18 11.2 0.8 24 4.4 0.1 3.1 2 0 0 2 2 2 0 arg-2/CPA1 leader peptide Pex14_N PF04695.13 PRP84272.1 - 0.41 11.3 6.6 0.16 12.6 3.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PARM PF17061.5 PRP84273.1 - 4.9e-06 26.9 26.3 4.9e-06 26.9 26.3 2.4 2 0 0 2 2 2 1 PARM Podoplanin PF05808.11 PRP84273.1 - 7e-05 23.0 0.2 7e-05 23.0 0.2 3.5 2 1 1 3 3 3 1 Podoplanin Pkinase_Tyr PF07714.17 PRP84275.1 - 4.4e-45 154.0 0.0 7.1e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84275.1 - 5.9e-34 117.6 0.0 1.2e-33 116.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Mid2 PF04478.12 PRP84275.1 - 2.7e-06 27.3 2.0 0.028 14.3 0.1 2.7 2 0 0 2 2 2 2 Mid2 like cell wall stress sensor LapA_dom PF06305.11 PRP84275.1 - 0.0015 18.3 1.6 1.7 8.6 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain EF-hand_1 PF00036.32 PRP84275.1 - 0.0017 17.8 0.3 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 EF hand KCT2 PF17818.1 PRP84275.1 - 0.0018 18.4 0.9 1.2 9.2 0.1 2.4 2 0 0 2 2 2 2 Keratinocyte-associated gene product Kdo PF06293.14 PRP84275.1 - 0.027 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YajC PF02699.15 PRP84275.1 - 0.062 13.2 1.2 15 5.6 0.1 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit EphA2_TM PF14575.6 PRP84275.1 - 0.064 14.1 0.0 23 5.9 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain EURL PF06937.11 PRP84275.1 - 0.14 11.6 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 EURL protein DUF3792 PF12670.7 PRP84275.1 - 0.16 12.1 12.9 1.8 8.7 0.3 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) EF-hand_6 PF13405.6 PRP84275.1 - 0.17 11.9 0.3 17 5.7 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain 7TM_GPCR_Srz PF10325.9 PRP84275.1 - 0.22 10.8 0.7 21 4.4 0.1 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz Pentapeptide_4 PF13599.6 PRP84275.1 - 0.96 9.7 3.9 3.5 7.9 1.3 3.3 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Adeno_E1B_55K PF01696.17 PRP84275.1 - 1.8 7.2 5.3 0.39 9.3 1.4 1.9 2 0 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Pep_deformylase PF01327.21 PRP84276.1 - 1.5e-28 99.4 0.0 1.9e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Birna_VP2 PF01766.17 PRP84276.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Birnavirus VP2 protein Cadherin_3 PF16184.5 PRP84278.1 - 7.3e-13 48.5 28.0 0.0031 17.5 0.0 14.8 19 0 0 19 19 19 4 Cadherin-like Big_9 PF17963.1 PRP84278.1 - 0.00036 21.2 8.4 0.00036 21.2 8.4 29.7 25 6 2 27 27 27 15 Bacterial Ig domain C1q PF00386.21 PRP84278.1 - 0.057 13.6 1.8 12 6.1 0.1 3.5 3 0 0 3 3 3 0 C1q domain Y_Y_Y PF07495.13 PRP84278.1 - 0.45 10.5 4.7 2.2 8.3 0.0 4.0 4 0 0 4 4 4 0 Y_Y_Y domain DUF2614 PF11023.8 PRP84280.1 - 0.32 11.1 2.7 1.3 9.2 2.7 2.0 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF202 PF02656.15 PRP84280.1 - 4.4 7.8 15.0 16 6.0 5.7 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) PLDc_2 PF13091.6 PRP84281.1 - 3.5e-18 65.8 0.0 2e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 PRP84281.1 - 0.00013 22.0 5.6 0.023 14.9 0.3 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif RE_NgoFVII PF09565.10 PRP84281.1 - 0.00033 20.1 0.0 0.44 9.8 0.0 2.6 3 0 0 3 3 3 2 NgoFVII restriction endonuclease Bac_rhamnosid6H PF17389.2 PRP84281.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Polysacc_synt_C PF14667.6 PRP84282.1 - 0.015 15.4 4.1 0.026 14.6 0.6 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Amino_oxidase PF01593.24 PRP84283.1 - 3.2e-14 53.1 0.0 1.2e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase GATA PF00320.27 PRP84283.1 - 1.6e-11 43.6 7.4 2.9e-11 42.8 7.4 1.4 1 0 0 1 1 1 1 GATA zinc finger NAD_binding_8 PF13450.6 PRP84283.1 - 7.4e-11 42.1 0.4 3.1e-10 40.1 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP84283.1 - 4.6e-08 33.0 2.6 0.00017 21.3 1.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP84283.1 - 1.8e-05 24.1 0.0 0.00023 20.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PRP84283.1 - 4.3e-05 22.9 0.0 9.5e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 PRP84283.1 - 0.0002 21.9 0.7 0.14 12.8 0.7 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PRP84283.1 - 0.0009 18.7 0.0 0.0051 16.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PRP84283.1 - 0.0038 16.5 0.0 0.018 14.3 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 PRP84283.1 - 0.0056 15.8 0.1 0.51 9.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 PRP84283.1 - 0.017 13.8 0.1 0.26 9.9 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 PRP84283.1 - 0.026 13.6 5.0 0.13 11.3 0.8 2.4 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 PRP84283.1 - 0.052 12.6 3.3 0.18 10.8 0.6 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 PRP84283.1 - 0.16 11.5 0.1 0.38 10.3 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sas10 PF09368.10 PRP84284.1 - 0.35 11.4 4.6 0.86 10.1 4.1 1.8 1 1 1 2 2 2 0 Sas10 C-terminal domain CMD PF02627.20 PRP84285.1 - 1.4e-14 53.8 0.7 2.7e-06 27.3 0.1 2.4 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family SinI PF08671.10 PRP84285.1 - 0.0043 16.8 2.1 1.3 8.9 0.2 2.6 2 0 0 2 2 2 2 Anti-repressor SinI PAS_8 PF13188.7 PRP84285.1 - 0.019 15.0 0.3 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 PAS domain TetR_C_28 PF17937.1 PRP84285.1 - 0.04 14.4 0.0 16 6.1 0.0 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MAGE PF01454.19 PRP84286.1 - 1.1e-24 87.3 0.0 1.8e-22 80.1 0.0 2.9 2 1 0 2 2 2 1 MAGE family Prefoldin_2 PF01920.20 PRP84287.1 - 6.9e-15 54.9 7.1 8e-15 54.7 7.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Lectin_N PF03954.14 PRP84287.1 - 0.0045 16.7 0.2 0.0091 15.7 0.2 1.4 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain FAM184 PF15665.5 PRP84287.1 - 0.011 15.5 1.8 0.015 15.1 1.8 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Helicase_C_3 PF13625.6 PRP84287.1 - 0.05 13.8 0.0 0.1 12.8 0.0 1.6 1 1 0 1 1 1 0 Helicase conserved C-terminal domain SlyX PF04102.12 PRP84287.1 - 0.079 13.6 4.3 0.33 11.6 0.7 2.2 2 0 0 2 2 2 0 SlyX DUF5320 PF17253.2 PRP84287.1 - 0.17 12.9 1.5 3.1 8.9 0.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) ANAPC4_WD40 PF12894.7 PRP84288.1 - 2.4e-05 24.6 0.0 0.37 11.1 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP84288.1 - 0.0002 22.1 0.9 0.55 11.2 1.4 3.9 2 1 0 2 2 2 1 WD domain, G-beta repeat OCRE PF17780.1 PRP84288.1 - 2.4 8.3 4.8 1.4 9.0 0.1 2.9 4 0 0 4 4 4 0 OCRE domain RTP PF02334.16 PRP84289.1 - 0.07 13.8 4.7 0.077 13.6 3.9 1.4 1 1 0 1 1 1 0 Replication terminator protein AROS PF15684.5 PRP84289.1 - 0.26 11.9 14.6 1.8 9.2 2.2 2.1 1 1 1 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 ECH_2 PF16113.5 PRP84290.1 - 2.2e-108 362.7 0.0 4.2e-108 361.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PRP84290.1 - 3.9e-27 95.2 0.0 3.8e-26 91.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SpoVIF PF14069.6 PRP84290.1 - 0.031 14.1 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Stage VI sporulation protein F Hairpins PF04877.12 PRP84290.1 - 0.052 13.2 0.2 0.096 12.3 0.2 1.3 1 0 0 1 1 1 0 HrpZ Homeodomain PF00046.29 PRP84291.1 - 1.2e-15 57.0 4.0 1.2e-15 57.0 4.0 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP84291.1 - 6.9e-07 29.1 1.3 2.7e-06 27.2 0.3 2.4 2 0 0 2 2 2 1 Homeobox KN domain DUF521 PF04412.13 PRP84291.1 - 0.024 13.3 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MRP-63 PF14978.6 PRP84291.1 - 0.059 14.0 0.4 0.14 12.8 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 U-box PF04564.15 PRP84292.1 - 8.2e-14 51.5 0.2 3.5e-13 49.5 0.0 2.2 2 0 0 2 2 2 1 U-box domain TIG PF01833.24 PRP84292.1 - 8e-08 32.3 0.2 3.1e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 IPT/TIG domain SAM_2 PF07647.17 PRP84292.1 - 0.00013 22.0 0.4 0.73 10.0 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) zf-NOSIP PF15906.5 PRP84292.1 - 0.0055 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein GRIM-19 PF06212.12 PRP84292.1 - 0.098 12.6 0.2 0.49 10.3 0.1 2.2 2 0 0 2 2 2 0 GRIM-19 protein SAM_PNT PF02198.16 PRP84292.1 - 0.1 12.6 0.5 0.3 11.1 0.1 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 PRP84292.1 - 0.2 12.1 2.6 1.8 9.0 0.2 2.6 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) DHR10 PF18595.1 PRP84292.1 - 1.7 8.7 11.3 4.4 7.4 5.3 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Pyr_redox_2 PF07992.14 PRP84293.1 - 2.5e-56 191.1 0.4 3.8e-56 190.5 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP84293.1 - 3.3e-19 69.2 0.1 6e-10 39.5 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 PRP84293.1 - 1.5e-17 63.3 0.0 3.4e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.6 PRP84293.1 - 6.6e-12 45.3 1.2 7.4e-09 35.3 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 PRP84293.1 - 2.2e-10 40.4 0.1 1e-09 38.2 0.0 2.2 3 0 0 3 3 2 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 PRP84293.1 - 6.9e-08 32.9 0.0 2e-07 31.4 0.0 1.8 2 0 0 2 2 1 1 Reductase C-terminal DAO PF01266.24 PRP84293.1 - 4.5e-06 26.5 0.7 0.39 10.2 0.6 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP84293.1 - 1.4e-05 25.2 0.2 0.0041 17.3 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PRP84293.1 - 0.00012 21.0 0.6 0.53 8.9 0.6 3.1 3 0 0 3 3 3 2 HI0933-like protein DUF1188 PF06690.11 PRP84293.1 - 0.00018 21.1 0.0 0.0045 16.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 PRP84293.1 - 0.00022 21.2 0.3 7.3 6.6 0.3 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.18 PRP84293.1 - 0.007 16.6 0.7 0.57 10.5 0.0 2.9 2 1 1 3 3 3 1 TrkA-N domain Thi4 PF01946.17 PRP84293.1 - 0.019 14.2 2.2 0.21 10.8 0.5 2.5 2 1 0 2 2 2 0 Thi4 family ThiF PF00899.21 PRP84293.1 - 0.052 12.9 4.0 1.5 8.1 1.7 3.0 2 1 1 3 3 3 0 ThiF family FAD_binding_3 PF01494.19 PRP84293.1 - 0.11 11.7 0.5 0.56 9.4 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 PRP84293.1 - 0.13 11.0 0.4 3.7 6.3 0.0 2.8 2 1 1 3 3 3 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.19 PRP84293.1 - 0.14 11.5 1.8 5.8 6.2 0.0 3.3 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 PRP84293.1 - 0.18 10.8 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 PRP84293.1 - 0.29 10.2 6.3 0.47 9.5 0.9 2.4 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 PRP84293.1 - 1.3 8.1 6.7 3.6 6.6 0.1 2.9 2 1 1 3 3 3 0 Glucose inhibited division protein A APC1_C PF18122.1 PRP84294.1 - 4e-11 43.1 1.3 8.6e-11 42.1 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 PRP84294.1 - 4.8e-05 23.6 0.2 0.0095 16.3 0.1 2.9 2 0 0 2 2 2 2 Proteasome/cyclosome repeat EF-hand_1 PF00036.32 PRP84296.1 - 3.5e-11 41.8 0.0 0.00021 20.6 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP84296.1 - 1.2e-09 37.3 0.0 0.00088 19.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PRP84296.1 - 7.3e-09 36.0 0.1 1.1e-08 35.5 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PRP84296.1 - 5.2e-08 32.0 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PRP84296.1 - 1.6e-05 24.7 0.1 0.00083 19.2 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 PRP84296.1 - 0.24 11.3 0.1 15 5.5 0.1 2.1 1 1 1 2 2 2 0 EF hand CCDC-167 PF15188.6 PRP84297.1 - 0.067 13.5 2.8 10 6.6 0.6 2.7 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 LOH1CR12 PF10158.9 PRP84297.1 - 0.088 12.8 1.5 0.33 11.0 0.3 2.5 2 1 0 2 2 2 0 Tumour suppressor protein Med30 PF11315.8 PRP84297.1 - 0.13 12.5 4.6 0.13 12.4 1.6 2.2 2 0 0 2 2 2 0 Mediator complex subunit 30 FlxA PF14282.6 PRP84297.1 - 1 9.4 4.9 1.6 8.7 0.2 2.4 2 0 0 2 2 2 0 FlxA-like protein Prefoldin_2 PF01920.20 PRP84297.1 - 1.2 9.1 7.5 7.8 6.5 4.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit UvrD-helicase PF00580.21 PRP84297.1 - 1.6 8.2 12.1 0.82 9.1 2.1 2.1 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Tmemb_cc2 PF10267.9 PRP84298.1 - 0.2 10.8 7.2 0.27 10.3 7.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein NDK PF00334.19 PRP84299.1 - 1e-51 174.5 0.0 1.5e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Spiralin PF05215.13 PRP84299.1 - 0.092 12.1 0.6 0.14 11.5 0.6 1.2 1 0 0 1 1 1 0 Spiralin SAP PF02037.27 PRP84302.1 - 6.5e-08 32.2 0.4 1.4e-07 31.0 0.4 1.7 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 PRP84302.1 - 0.0046 16.6 0.1 0.012 15.2 0.1 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal Cellulase PF00150.18 PRP84303.1 - 1.3e-20 74.0 2.7 1.7e-20 73.6 2.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 PRP84303.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) ANAPC4_WD40 PF12894.7 PRP84304.1 - 1.9e-13 50.5 0.1 2.8e-05 24.3 0.0 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP84304.1 - 1.1e-12 48.3 12.6 0.00012 22.8 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat LisH_TPL PF17814.1 PRP84304.1 - 3e-07 30.0 0.0 1.1e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 LisH-like dimerisation domain PQQ PF01011.21 PRP84304.1 - 0.0024 17.7 0.0 0.0071 16.2 0.0 1.8 1 0 0 1 1 1 1 PQQ enzyme repeat eIF2A PF08662.11 PRP84304.1 - 0.016 15.1 0.4 2.6 7.9 0.0 2.7 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Cwf_Cwc_15 PF04889.12 PRP84305.1 - 1.2e-67 228.3 23.1 1.4e-67 228.0 23.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 PRP84305.1 - 0.00029 20.8 22.1 0.00036 20.5 22.1 1.2 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing AF-4 PF05110.13 PRP84305.1 - 0.036 12.2 22.8 0.013 13.7 20.1 1.3 1 1 0 1 1 1 0 AF-4 proto-oncoprotein Asp-B-Hydro_N PF05279.11 PRP84305.1 - 0.63 10.1 21.1 0.85 9.6 21.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Baculo_PEP_C PF04513.12 PRP84306.1 - 0.00019 21.5 0.6 0.00019 21.5 0.6 4.1 4 0 0 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 PRP84307.1 - 1.6e-40 136.3 19.9 3.2e-09 37.2 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84307.1 - 1.8e-14 53.8 0.0 0.0046 17.2 0.0 5.6 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP84307.1 - 1.8e-07 31.2 0.0 0.029 14.3 0.0 2.6 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PRP84307.1 - 1.2e-06 28.1 0.1 5.8e-05 22.6 0.1 2.7 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 PRP84307.1 - 0.00047 19.2 2.2 3.2 6.6 0.0 4.0 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Tnp_22_trimer PF17489.2 PRP84307.1 - 0.038 14.0 1.6 0.087 12.8 1.6 1.6 1 0 0 1 1 1 0 L1 transposable element trimerization domain CREPT PF16566.5 PRP84307.1 - 0.18 11.9 0.9 0.27 11.4 0.9 1.2 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF202 PF02656.15 PRP84309.1 - 4.5e-20 71.9 2.3 4.5e-20 71.9 2.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LtrA PF06772.11 PRP84309.1 - 0.024 13.9 2.5 0.058 12.6 2.9 1.3 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) YtpI PF14007.6 PRP84309.1 - 0.067 13.3 0.2 0.067 13.3 0.2 2.0 2 0 0 2 2 2 0 YtpI-like protein DUF4199 PF13858.6 PRP84309.1 - 0.68 10.3 7.6 0.81 10.1 6.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Claudin_2 PF13903.6 PRP84309.1 - 1.3 8.7 7.3 1.7 8.4 0.3 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MotA_ExbB PF01618.16 PRP84309.1 - 9 6.1 7.6 91 2.8 7.6 2.5 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family AMPK1_CBM PF16561.5 PRP84310.1 - 3.5e-14 52.8 0.2 5.7e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 PRP84310.1 - 0.0022 18.3 0.1 0.0049 17.2 0.1 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Methyltransf_15 PF09445.10 PRP84311.1 - 7.1e-39 133.0 0.0 9.6e-39 132.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 PRP84311.1 - 8.7e-09 36.0 0.0 1.8e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP84311.1 - 1e-07 31.9 0.1 2.3e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 PRP84311.1 - 1.4e-07 31.4 1.4 4.4e-07 29.8 0.2 2.2 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Met_10 PF02475.16 PRP84311.1 - 2.8e-06 27.3 1.1 6.4e-06 26.1 0.0 2.0 2 1 0 2 2 2 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 PRP84311.1 - 4.5e-06 26.4 0.0 7.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 PRP84311.1 - 2.8e-05 24.7 0.0 6.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 PRP84311.1 - 3e-05 24.0 0.2 6e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP84311.1 - 4.5e-05 23.1 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PRP84311.1 - 0.00024 20.6 0.3 0.00044 19.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 PRP84311.1 - 0.0018 17.5 0.0 0.0021 17.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_3 PF01596.17 PRP84311.1 - 0.0019 17.4 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_5 PF01795.19 PRP84311.1 - 0.0032 17.0 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 MraW methylase family Ubie_methyltran PF01209.18 PRP84311.1 - 0.0032 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UDPG_MGDP_dh_N PF03721.14 PRP84311.1 - 0.0058 16.2 0.3 0.043 13.4 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_32 PF13679.6 PRP84311.1 - 0.015 15.3 0.0 0.029 14.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CmcI PF04989.12 PRP84311.1 - 0.016 14.9 1.8 0.017 14.8 0.1 1.8 2 0 0 2 2 2 0 Cephalosporin hydroxylase tRNA_U5-meth_tr PF05958.11 PRP84311.1 - 0.026 13.5 0.0 0.098 11.6 0.0 1.8 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase MethyltransfD12 PF02086.15 PRP84311.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_24 PF13578.6 PRP84311.1 - 0.086 13.9 0.0 0.18 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FXR_C1 PF16096.5 PRP84311.1 - 0.13 12.5 1.2 0.25 11.5 1.2 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 ECH_1 PF00378.20 PRP84312.1 - 1.6e-83 279.8 2.5 2e-83 279.6 2.5 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP84312.1 - 2.9e-41 142.1 1.0 3.7e-41 141.7 1.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 PRP84312.1 - 0.019 14.9 1.4 0.033 14.2 0.0 2.1 3 0 0 3 3 3 0 Peptidase family S49 DUF3813 PF12758.7 PRP84312.1 - 0.066 13.6 0.2 0.22 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Cofilin_ADF PF00241.20 PRP84313.1 - 9.9e-19 67.3 0.0 1.6e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 PRP84313.1 - 7.7e-17 60.6 0.3 2.2e-16 59.2 0.3 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP84313.1 - 1.2e-16 60.3 1.1 6.9e-15 54.6 0.3 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 PRP84313.1 - 2.2e-13 49.6 0.0 5.2e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Thioredoxin PF00085.20 PRP84314.1 - 1.6e-16 60.1 0.0 3.7e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PRP84314.1 - 0.00095 19.6 0.1 0.019 15.4 0.1 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 PRP84314.1 - 0.0049 16.9 0.4 0.018 15.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_8 PF13905.6 PRP84314.1 - 0.016 15.5 0.6 8.3 6.8 0.0 3.2 2 1 1 3 3 3 0 Thioredoxin-like Noc2 PF03715.13 PRP84314.1 - 0.028 13.7 0.6 0.05 12.8 0.6 1.3 1 0 0 1 1 1 0 Noc2p family HyaE PF07449.11 PRP84314.1 - 0.075 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE HrcA PF01628.21 PRP84314.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 HrcA protein C terminal domain OST3_OST6 PF04756.13 PRP84314.1 - 0.12 11.7 1.7 0.19 11.1 0.1 2.2 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 PRP84314.1 - 0.16 12.1 0.1 0.48 10.6 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin Pkinase PF00069.25 PRP84315.1 - 4.6e-62 209.8 0.1 6.6e-62 209.2 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84315.1 - 3.9e-43 147.6 0.0 6e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP84315.1 - 4.5e-06 25.7 0.1 7.6e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP84315.1 - 6.6e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP84315.1 - 0.0042 16.1 0.7 0.0071 15.3 0.7 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PRP84315.1 - 0.0071 15.4 0.2 0.013 14.6 0.2 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 PRP84315.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ELM2 PF01448.24 PRP84316.1 - 9.4e-05 23.1 0.1 0.00021 22.0 0.1 1.7 1 0 0 1 1 1 1 ELM2 domain Chromo PF00385.24 PRP84317.1 - 5e-13 48.7 1.0 5e-13 48.7 1.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain CLP1_P PF16575.5 PRP84318.1 - 1.2e-36 126.3 0.0 2.2e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 PRP84318.1 - 0.00082 18.7 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 PRP84318.1 - 0.001 19.5 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 PRP84318.1 - 0.0018 18.8 0.0 0.0046 17.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 PRP84318.1 - 0.019 15.1 0.1 0.054 13.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP84318.1 - 0.031 14.0 0.1 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 PRP84318.1 - 0.04 13.8 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 PRP84318.1 - 0.045 13.1 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 PRP84318.1 - 0.056 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PRP84318.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.20 PRP84318.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 PRP84318.1 - 0.14 12.7 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ndc1_Nup PF09531.10 PRP84318.1 - 6.3 5.4 5.3 9 4.9 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 PRP84319.1 - 4.1e-43 145.1 0.1 9.6e-16 57.4 0.0 3.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PRP84319.1 - 0.0011 18.9 0.0 0.17 11.9 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 PRP84319.1 - 0.0011 18.9 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PRP84319.1 - 0.0087 16.2 0.0 12 6.1 0.0 3.5 2 1 1 3 3 3 1 RNA recognition motif PHM7_cyt PF14703.6 PRP84319.1 - 0.014 15.6 3.3 8.7 6.5 0.0 4.2 2 2 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter RrnaAD PF00398.20 PRP84319.1 - 0.018 14.1 0.1 0.038 13.1 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase DNA_topoisoIV PF00521.20 PRP84319.1 - 0.035 13.0 0.0 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A DUF1866 PF08952.11 PRP84319.1 - 0.12 12.2 0.0 1.2 9.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) Pes-10 PF07149.11 PRP84319.1 - 0.13 11.3 0.4 0.21 10.6 0.4 1.2 1 0 0 1 1 1 0 Pes-10 Ribul_P_3_epim PF00834.19 PRP84321.1 - 3.8e-47 160.3 1.3 1.1e-45 155.4 0.3 2.0 1 1 1 2 2 2 2 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.21 PRP84321.1 - 0.0004 19.9 0.0 0.0072 15.8 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.19 PRP84321.1 - 0.038 13.8 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Ribosomal_S24e PF01282.19 PRP84322.1 - 4e-31 106.8 0.0 1.8e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S24e AAA_23 PF13476.6 PRP84324.1 - 4.8e-30 105.6 16.7 4.8e-30 105.6 16.7 8.5 1 1 3 5 5 1 1 AAA domain AAA_21 PF13304.6 PRP84324.1 - 1.1e-09 38.6 3.3 0.00024 21.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PRP84324.1 - 6.6e-09 36.0 30.4 7.8e-08 32.4 9.6 5.6 1 1 1 4 4 3 2 AAA ATPase domain SMC_N PF02463.19 PRP84324.1 - 9.4e-09 35.0 0.0 9.4e-09 35.0 0.0 3.8 3 2 0 3 3 2 1 RecF/RecN/SMC N terminal domain Rad50_zn_hook PF04423.14 PRP84324.1 - 2.4e-06 27.3 0.2 2.4e-06 27.3 0.2 6.7 7 1 1 8 8 8 1 Rad50 zinc hook motif SbcCD_C PF13558.6 PRP84324.1 - 2.6e-05 24.4 0.3 0.00011 22.4 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit CREPT PF16566.5 PRP84324.1 - 0.00054 20.2 16.8 0.00085 19.5 3.2 9.7 6 4 3 9 9 9 2 Cell-cycle alteration and expression-elevated protein in tumour AAA_29 PF13555.6 PRP84324.1 - 0.0084 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 PRP84324.1 - 0.022 14.7 0.1 1.4 8.9 0.0 3.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP84324.1 - 0.03 14.6 0.0 0.03 14.6 0.0 5.5 6 2 1 7 7 7 0 AAA domain AAA_16 PF13191.6 PRP84324.1 - 0.65 10.4 0.0 0.65 10.4 0.0 4.8 4 2 0 4 4 3 0 AAA ATPase domain WD40 PF00400.32 PRP84326.1 - 6.4e-21 74.3 9.9 5e-06 27.1 0.1 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84326.1 - 5.8e-07 29.7 0.0 0.13 12.6 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP84326.1 - 0.00023 20.0 0.2 0.19 10.4 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 DUF5111 PF17138.4 PRP84326.1 - 0.11 12.4 0.1 1.8 8.4 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5111) Zip PF02535.22 PRP84327.1 - 6.6e-44 150.5 19.6 1.7e-41 142.5 19.6 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Ceramidase PF05875.12 PRP84327.1 - 0.084 12.3 0.5 0.16 11.4 0.5 1.4 1 0 0 1 1 1 0 Ceramidase Bundlin PF05307.11 PRP84327.1 - 0.55 10.1 2.1 26 4.7 0.1 2.6 2 0 0 2 2 2 0 Bundlin Bax1-I PF01027.20 PRP84327.1 - 1.9 8.3 12.1 3.4 7.5 5.4 2.7 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Pkinase PF00069.25 PRP84328.1 - 4.7e-36 124.5 0.0 7.4e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84328.1 - 5.8e-21 74.9 0.0 1.1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH PF00642.24 PRP84328.1 - 0.00014 21.6 5.6 0.0008 19.3 0.2 3.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PRP84328.1 - 0.00055 19.9 1.5 0.00055 19.9 1.5 2.6 2 0 0 2 2 2 1 Zinc finger domain Kinase-like PF14531.6 PRP84328.1 - 0.054 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 PRP84328.1 - 0.099 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-CCCH_4 PF18044.1 PRP84328.1 - 1.4 8.8 9.0 0.058 13.2 0.6 2.8 3 0 0 3 3 3 0 CCCH-type zinc finger Myosin_head PF00063.21 PRP84330.1 - 1.1e-253 843.5 7.9 2e-253 842.6 7.9 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) MyTH4 PF00784.17 PRP84330.1 - 1.9e-56 189.2 0.5 1.3e-29 102.9 0.0 3.3 3 0 0 3 3 3 2 MyTH4 domain Pkinase_Tyr PF07714.17 PRP84330.1 - 1.2e-27 96.9 0.0 2.9e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84330.1 - 4.6e-17 62.3 0.0 1.2e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain FERM_M PF00373.18 PRP84330.1 - 7.6e-14 52.1 0.0 8.4e-06 26.2 0.0 3.2 2 0 0 2 2 2 2 FERM central domain FERM_N PF09379.10 PRP84330.1 - 2.7e-06 27.2 0.1 0.003 17.5 0.1 2.9 2 0 0 2 2 2 2 FERM N-terminal domain IQ PF00612.27 PRP84330.1 - 5.7e-06 25.7 21.8 0.00014 21.3 1.4 4.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_22 PF13401.6 PRP84330.1 - 2.9e-05 24.4 1.2 0.04 14.2 0.0 4.4 4 0 0 4 4 4 1 AAA domain SH3_1 PF00018.28 PRP84330.1 - 7e-05 22.4 0.0 0.0002 20.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP84330.1 - 0.00088 18.9 0.0 0.0029 17.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.23 PRP84330.1 - 0.0016 19.0 0.2 1.5 9.5 0.0 4.1 4 0 0 4 4 4 1 Ras association (RalGDS/AF-6) domain AAA_16 PF13191.6 PRP84330.1 - 0.032 14.6 3.0 0.055 13.9 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 PRP84330.1 - 0.2 12.1 0.0 0.2 12.1 0.0 2.9 2 0 0 2 2 1 0 ABC transporter Neur_chan_memb PF02932.16 PRP84330.1 - 5 7.1 9.6 18 5.3 9.6 1.9 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PPP4R2 PF09184.11 PRP84330.1 - 7.6 6.0 20.4 16 4.9 20.4 1.5 1 0 0 1 1 1 0 PPP4R2 Clat_adaptor_s PF01217.20 PRP84332.1 - 1e-18 67.7 0.1 1.6e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PAH PF02671.21 PRP84333.1 - 4e-25 87.7 14.2 1.1e-15 57.4 0.1 3.8 3 1 0 3 3 3 3 Paired amphipathic helix repeat X8 PF07983.13 PRP84334.1 - 3.3e-09 37.3 1.2 8.3e-09 36.0 1.2 1.7 1 0 0 1 1 1 1 X8 domain Activator_LAG-3 PF11498.8 PRP84334.1 - 0.57 9.1 2.3 5.4 5.9 0.5 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 LRR_6 PF13516.6 PRP84335.1 - 2.7e-13 48.8 1.6 0.00018 21.3 0.0 4.9 5 0 0 5 5 5 4 Leucine Rich repeat Aa_trans PF01490.18 PRP84336.1 - 1.5e-13 50.3 29.0 4.1e-13 48.8 29.0 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5373 PF17343.2 PRP84336.1 - 0.33 10.8 0.0 0.33 10.8 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5373) DUF2013 PF09431.10 PRP84337.1 - 1.6e-21 76.9 0.1 5.5e-21 75.2 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) PPV_E2_C PF00511.17 PRP84338.1 - 0.0038 17.4 0.0 0.0046 17.1 0.0 1.1 1 0 0 1 1 1 1 E2 (early) protein, C terminal Maf1 PF09174.10 PRP84338.1 - 0.051 13.7 0.0 0.054 13.7 0.0 1.1 1 0 0 1 1 1 0 Maf1 regulator Metallophos PF00149.28 PRP84339.1 - 1.6e-13 51.6 1.7 2.4e-13 51.1 1.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_8 PF13855.6 PRP84340.1 - 4.3e-30 103.3 67.4 1.8e-09 37.2 4.2 6.8 1 1 5 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 PRP84340.1 - 5.8e-27 93.3 55.4 9.8e-07 29.0 3.5 7.8 3 1 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP84340.1 - 4e-08 32.7 36.7 1.1 10.0 0.2 12.0 12 2 0 12 12 12 3 Leucine Rich Repeat LRR_9 PF14580.6 PRP84340.1 - 2.9e-07 30.1 26.2 0.0018 17.8 2.0 4.4 1 1 2 4 4 4 4 Leucine-rich repeat FGGY_N PF00370.21 PRP84340.1 - 0.023 14.3 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain LRR_6 PF13516.6 PRP84340.1 - 2.2 8.5 0.0 2.2 8.5 0.0 11.4 13 0 0 13 13 13 0 Leucine Rich repeat RF-1 PF00472.20 PRP84342.1 - 6.3e-15 55.1 8.3 6.3e-15 55.1 8.3 2.4 1 1 1 2 2 2 1 RF-1 domain CUB_2 PF02408.20 PRP84342.1 - 0.035 13.9 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 CUB-like domain HemY_N PF07219.13 PRP84342.1 - 0.15 12.2 2.8 0.28 11.4 2.7 1.5 1 1 0 1 1 1 0 HemY protein N-terminus Neur_chan_memb PF02932.16 PRP84342.1 - 1.9 8.5 4.2 2.2 8.3 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.15 PRP84342.1 - 3.6 6.4 4.6 4 6.3 4.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CCDC53 PF10152.9 PRP84342.1 - 4 7.9 11.0 5.2 7.5 11.0 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 PRP84342.1 - 9.3 4.9 11.4 11 4.7 11.4 1.1 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 PRP84342.1 - 9.5 5.0 12.3 10 4.9 12.3 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Zip PF02535.22 PRP84342.1 - 9.7 5.3 5.9 11 5.1 5.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNB PF00773.19 PRP84343.1 - 3.1e-99 332.4 0.1 5.1e-99 331.7 0.1 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PRP84343.1 - 4e-22 78.0 0.0 9.2e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 PRP84343.1 - 7e-15 55.0 0.0 1.6e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 PRP84343.1 - 8e-15 55.3 0.7 2e-14 54.0 0.7 1.7 1 0 0 1 1 1 1 PIN domain Rrp44_S1 PF17215.3 PRP84343.1 - 2.2e-11 43.6 0.1 5.8e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 PRP84343.1 - 2.9e-07 30.6 2.1 8.1e-05 22.7 0.3 3.5 3 0 0 3 3 3 1 Cold shock domain Dis3l2_C_term PF17877.1 PRP84343.1 - 0.0019 18.5 0.1 0.0058 16.9 0.1 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Pescadillo_N PF06732.11 PRP84344.1 - 1.6e-82 277.2 0.8 3.4e-82 276.1 0.8 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 PRP84344.1 - 0.0069 16.8 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain FTR PF01913.18 PRP84345.1 - 0.0072 16.3 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Formylmethanofuran-tetrahydromethanopterin formyltransferase Glyco_transf_92 PF01697.27 PRP84346.1 - 9.7e-12 45.1 1.6 1.5e-11 44.5 1.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PRP84346.1 - 7.3e-06 26.4 0.1 2.5e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 THF_DHG_CYH_C PF02882.19 PRP84347.1 - 5.6e-69 230.5 0.6 2.2e-68 228.6 0.3 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 PRP84347.1 - 2.4e-39 134.2 1.6 4.1e-39 133.4 1.6 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Oxidored_nitro PF00148.19 PRP84347.1 - 0.077 11.7 0.0 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TIP_N PF12457.8 PRP84348.1 - 0.0073 16.7 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal Ribosomal_L6 PF00347.23 PRP84349.1 - 7.7e-26 90.6 3.1 1.1e-13 51.7 0.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Pkinase PF00069.25 PRP84350.1 - 5.5e-76 255.4 0.0 6.8e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84350.1 - 6.9e-35 120.6 0.0 9.1e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP84350.1 - 1.4e-05 24.5 0.0 0.00017 21.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PRP84350.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP84350.1 - 0.0011 18.6 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PRP84350.1 - 0.0019 17.9 0.4 0.36 10.4 0.0 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 zf-C3HC4_3 PF13920.6 PRP84351.1 - 2.4e-11 43.3 8.6 1.4e-10 40.9 7.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP84351.1 - 4.3e-08 32.9 10.4 6e-08 32.4 8.0 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PRP84351.1 - 0.00068 19.9 9.4 0.00068 19.9 9.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PRP84351.1 - 0.00081 19.3 8.7 0.002 18.0 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PRP84351.1 - 2.3 8.1 12.1 1.5 8.7 8.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1996 PF09362.10 PRP84352.1 - 3.2e-28 99.3 0.0 5.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RicinB_lectin_2 PF14200.6 PRP84352.1 - 5.4e-07 30.2 0.8 0.00011 22.8 0.1 2.7 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 PRP84352.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 PRP84352.1 - 0.13 12.5 0.2 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 Fascin domain VPS9 PF02204.18 PRP84354.1 - 2.2e-13 50.3 0.6 3.7e-12 46.4 0.0 3.0 2 1 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain BLUF PF04940.12 PRP84354.1 - 0.013 15.6 0.2 0.057 13.5 0.2 2.1 1 0 0 1 1 1 0 Sensors of blue-light using FAD YojJ PF10372.9 PRP84354.1 - 1.4 9.0 4.6 4.8 7.3 1.1 2.8 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus AFOR_C PF01314.18 PRP84355.1 - 0.17 10.9 0.4 0.17 10.9 0.4 1.0 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 ELMO_CED12 PF04727.13 PRP84356.1 - 1.4e-39 136.0 0.0 3.5e-39 134.7 0.0 1.7 1 0 0 1 1 1 1 ELMO/CED-12 family adh_short PF00106.25 PRP84356.1 - 1.9e-11 43.8 0.0 5.5e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP84356.1 - 4.3e-08 33.0 0.0 7.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP84356.1 - 2.4e-07 30.8 0.0 7e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 KR domain DUF3361 PF11841.8 PRP84356.1 - 1.7e-06 28.0 0.3 1.7e-06 28.0 0.3 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) Sacchrp_dh_NADP PF03435.18 PRP84356.1 - 0.0017 18.6 0.2 0.0062 16.8 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 PRP84356.1 - 0.078 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TFIIB PF00382.19 PRP84357.1 - 1.4e-09 37.8 0.1 0.00011 22.1 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BSP_II PF05432.11 PRP84357.1 - 0.0021 17.8 12.7 0.0021 17.8 12.7 1.6 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) TF_Zn_Ribbon PF08271.12 PRP84357.1 - 0.0022 17.5 0.7 0.0061 16.1 0.7 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 PRP84357.1 - 0.069 12.9 0.1 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain SURF2 PF05477.11 PRP84357.1 - 3.1 7.4 14.8 7.8 6.1 14.8 1.6 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RXT2_N PF08595.11 PRP84357.1 - 3.4 7.7 15.9 0.26 11.3 10.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 PRP84357.1 - 3.9 6.7 13.9 8.8 5.5 13.9 1.6 1 0 0 1 1 1 0 NOA36 protein IncF PF17626.2 PRP84358.1 - 0.03 14.7 0.1 10 6.5 0.0 2.2 2 0 0 2 2 2 0 Inclusion membrane protein F Sugar_transport PF06800.12 PRP84358.1 - 0.046 13.1 3.5 0.042 13.2 1.1 1.8 1 1 1 2 2 2 0 Sugar transport protein DUF4156 PF13698.6 PRP84358.1 - 0.053 13.9 0.0 11 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4156) DUF5463 PF17551.2 PRP84358.1 - 0.057 13.3 1.6 0.14 12.1 1.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5463) START PF01852.19 PRP84359.1 - 6.5e-07 29.0 1.4 0.019 14.4 0.4 2.4 2 0 0 2 2 2 2 START domain Cation_efflux PF01545.21 PRP84360.1 - 3.4e-29 102.0 6.2 4.6e-29 101.6 6.2 1.2 1 0 0 1 1 1 1 Cation efflux family SUKH_5 PF14567.6 PRP84360.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall BTB_2 PF02214.22 PRP84361.1 - 1.1e-19 70.6 0.1 2.6e-18 66.2 0.0 2.3 2 0 0 2 2 2 1 BTB/POZ domain TLD PF07534.16 PRP84361.1 - 1.5e-17 64.1 0.4 3.3e-17 63.0 0.2 1.7 2 0 0 2 2 2 1 TLD BTB_3 PF16017.5 PRP84361.1 - 0.03 14.4 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain TPR_MLP1_2 PF07926.12 PRP84361.1 - 0.11 12.5 3.4 0.21 11.6 3.4 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF758 PF05527.11 PRP84362.1 - 5e-15 55.9 5.2 9.2e-15 55.1 5.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF758) PH PF00169.29 PRP84362.1 - 7.8e-13 48.8 2.0 1.1e-12 48.4 0.5 1.9 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 PRP84362.1 - 0.044 14.1 0.6 0.79 10.1 0.6 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 PRP84362.1 - 0.072 13.2 1.3 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology SRP_SPB PF02978.19 PRP84362.1 - 0.094 13.3 1.4 0.22 12.1 1.4 1.6 1 0 0 1 1 1 0 Signal peptide binding domain PH_11 PF15413.6 PRP84362.1 - 0.21 12.1 3.1 0.31 11.5 1.0 2.4 2 1 0 2 2 2 0 Pleckstrin homology domain PCNA_C PF02747.15 PRP84363.1 - 2.8e-11 43.7 0.0 1.3e-09 38.3 0.0 2.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 PRP84363.1 - 3.2e-11 43.0 1.1 6.1e-11 42.1 0.3 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain EamA PF00892.20 PRP84363.1 - 2.6e-10 40.6 39.2 1.1e-07 32.1 5.6 3.7 3 1 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 PRP84363.1 - 6.6e-09 35.4 2.5 6.6e-09 35.4 2.5 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 PRP84363.1 - 3.4e-06 26.8 5.0 3.4e-06 26.8 5.0 3.0 2 1 1 3 3 3 1 Solute carrier family 35 Hus1 PF04005.12 PRP84363.1 - 0.04 13.0 0.2 0.24 10.5 0.1 2.1 2 0 0 2 2 2 0 Hus1-like protein GAF_2 PF13185.6 PRP84364.1 - 3.1e-05 24.3 0.0 4.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PRP84364.1 - 0.0086 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain CUB PF00431.20 PRP84364.1 - 0.048 14.0 0.1 0.092 13.1 0.1 1.4 1 0 0 1 1 1 0 CUB domain Marek_A PF02124.15 PRP84364.1 - 0.083 12.7 0.4 0.13 12.1 0.4 1.2 1 0 0 1 1 1 0 Marek's disease glycoprotein A SH2 PF00017.24 PRP84366.1 - 2e-13 50.2 0.0 4.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 SH2 domain MFS_1 PF07690.16 PRP84367.1 - 1.7e-38 132.5 32.3 9.7e-38 130.0 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tho2 PF11262.8 PRP84368.1 - 1.2e-82 277.5 5.4 1.2e-82 277.5 5.4 8.4 4 1 4 8 8 8 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 PRP84368.1 - 4.9e-64 217.1 0.3 9.5e-43 146.8 0.0 10.1 5 3 5 10 10 10 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 PRP84368.1 - 3.8e-21 74.9 0.1 1.2e-20 73.4 0.1 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit RhoGEF PF00621.20 PRP84370.1 - 2.6e-27 96.2 0.6 4.1e-27 95.6 0.6 1.3 1 0 0 1 1 1 1 RhoGEF domain Sugar_tr PF00083.24 PRP84371.1 - 3.2e-73 247.1 28.4 3.2e-73 247.1 28.4 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP84371.1 - 7.5e-12 44.8 23.7 7.5e-12 44.8 23.7 3.3 2 2 1 3 3 3 2 Major Facilitator Superfamily SdpI PF13630.6 PRP84371.1 - 3.5e-05 23.9 3.2 3.5e-05 23.9 3.2 5.2 4 1 0 4 4 4 1 SdpI/YhfL protein family TMEM208_SND2 PF05620.11 PRP84371.1 - 3.4 7.4 6.0 0.8 9.5 1.0 2.5 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 LuxE PF04443.12 PRP84372.1 - 0.079 12.0 0.2 0.11 11.5 0.2 1.1 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE FtsH_ext PF06480.15 PRP84372.1 - 0.11 12.9 5.5 0.24 11.8 5.5 1.7 1 1 0 1 1 1 0 FtsH Extracellular RIFIN PF02009.16 PRP84372.1 - 0.18 11.7 2.1 0.22 11.4 2.1 1.2 1 0 0 1 1 1 0 Rifin Gelsolin PF00626.22 PRP84373.1 - 1.6e-44 149.7 0.3 2.1e-14 53.2 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Rsc14 PF08586.10 PRP84373.1 - 0.15 12.8 0.0 2.8 8.8 0.0 2.5 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Clc-like PF07062.12 PRP84374.1 - 0.00072 19.1 0.4 0.00072 19.1 0.4 1.6 2 0 0 2 2 2 1 Clc-like SUR7 PF06687.12 PRP84374.1 - 0.13 11.8 12.8 0.12 12.0 11.2 1.7 1 1 0 1 1 1 0 SUR7/PalI family Deltameth_res PF16020.5 PRP84374.1 - 1.9 8.4 4.4 0.88 9.5 0.1 2.6 3 0 0 3 3 3 0 Deltamethrin resistance BTP PF05232.12 PRP84374.1 - 3.1 7.9 9.7 14 5.8 6.9 2.7 2 1 1 3 3 3 0 Chlorhexidine efflux transporter Tmemb_cc2 PF10267.9 PRP84374.1 - 3.5 6.7 4.2 4.9 6.2 4.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Amastin PF07344.11 PRP84374.1 - 7.7 6.3 13.8 1.9 8.3 8.5 2.3 1 1 1 2 2 2 0 Amastin surface glycoprotein PH PF00169.29 PRP84375.1 - 1.1e-16 61.3 1.6 3.4e-16 59.7 0.4 2.7 2 0 0 2 2 2 1 PH domain Patatin PF01734.22 PRP84375.1 - 1e-12 48.6 0.0 3.4e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase PH_8 PF15409.6 PRP84375.1 - 0.0039 17.4 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain OTU PF02338.19 PRP84375.1 - 0.013 16.0 0.0 0.049 14.1 0.0 2.0 1 0 0 1 1 1 0 OTU-like cysteine protease zf-RING_UBOX PF13445.6 PRP84375.1 - 0.02 14.9 5.7 0.021 14.8 3.4 2.3 1 1 1 2 2 2 0 RING-type zinc-finger PH_3 PF14593.6 PRP84375.1 - 0.029 14.5 2.2 0.058 13.5 0.1 2.7 3 0 0 3 3 3 0 PH domain PH_9 PF15410.6 PRP84375.1 - 0.031 14.7 0.1 0.1 12.9 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain zf-C3HC4 PF00097.25 PRP84375.1 - 0.037 13.9 9.5 0.16 11.9 9.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP84375.1 - 0.037 14.3 8.5 0.11 12.9 8.5 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 PRP84375.1 - 0.052 13.5 8.1 0.13 12.2 8.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF2247 PF10004.9 PRP84375.1 - 0.1 12.4 1.2 0.94 9.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) PAN_4 PF14295.6 PRP84377.1 - 7.4e-10 38.6 5.8 7.4e-10 38.6 5.8 2.4 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PRP84377.1 - 7.2e-07 29.1 0.1 2.3e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP84377.1 - 1e-05 25.6 1.1 2.5e-05 24.3 1.1 1.6 1 0 0 1 1 1 1 PAN-like domain HA2 PF04408.23 PRP84378.1 - 7.1e-23 81.0 0.8 5e-22 78.2 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PRP84378.1 - 8.9e-13 48.4 0.0 2.2e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PRP84378.1 - 1.8e-11 44.4 0.0 5e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP84378.1 - 4.6e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PRP84378.1 - 4.8e-06 26.9 0.1 6.4e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 PRP84378.1 - 0.0062 17.1 4.4 0.11 13.1 1.0 3.4 1 1 1 2 2 2 1 ABC transporter AAA_33 PF13671.6 PRP84378.1 - 0.02 15.0 2.4 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP84378.1 - 0.025 14.3 0.1 0.066 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 PRP84378.1 - 0.027 13.5 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PRP84378.1 - 0.082 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 PRP84378.1 - 0.094 12.2 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1980 PF09323.10 PRP84379.1 - 0.00047 20.1 1.1 0.00082 19.3 0.3 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1980) EGF PF00008.27 PRP84379.1 - 0.0053 17.0 9.4 0.011 16.1 9.4 1.5 1 0 0 1 1 1 1 EGF-like domain SieB PF14163.6 PRP84379.1 - 0.037 13.5 0.3 0.037 13.5 0.3 2.8 2 1 1 3 3 3 0 Super-infection exclusion protein B EGF_2 PF07974.13 PRP84379.1 - 0.047 14.1 10.8 0.085 13.2 10.8 1.4 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 PRP84379.1 - 0.81 10.4 7.5 2.1 9.1 7.5 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF MRAP PF15183.6 PRP84379.1 - 4.9 7.2 8.5 17 5.5 1.0 3.8 3 1 1 4 4 4 0 Melanocortin-2 receptor accessory protein family DUF2237 PF09996.9 PRP84382.1 - 1.6e-47 160.3 0.0 1.9e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Glyco_transf_10 PF00852.19 PRP84383.1 - 5.9e-29 101.0 1.3 1.4e-28 99.8 1.3 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term EF-hand_7 PF13499.6 PRP84383.1 - 7.2e-26 90.4 1.0 4.8e-14 52.6 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP84383.1 - 2.8e-25 85.9 12.5 2e-07 30.1 2.6 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PRP84383.1 - 2.7e-23 79.8 6.4 1e-06 28.1 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PRP84383.1 - 8.5e-19 67.2 10.0 3.6e-09 36.3 0.9 4.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PRP84383.1 - 2e-12 46.0 9.7 0.00043 19.7 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 PRP84383.1 - 6.7e-10 39.2 0.0 1.2e-06 28.7 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 PRP84383.1 - 9.9e-05 22.5 0.1 0.0006 20.0 0.0 2.3 2 0 0 2 2 2 1 Dockerin type I domain EF-hand_4 PF12763.7 PRP84383.1 - 0.00025 21.0 0.2 0.3 11.1 0.0 2.9 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TPR_8 PF13181.6 PRP84383.1 - 0.0015 18.6 0.3 0.093 13.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 PRP84383.1 - 0.0016 18.2 2.2 0.029 14.1 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 PRP84383.1 - 0.0018 18.7 1.4 2.1 8.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP84383.1 - 0.0045 16.8 1.6 1.1 9.2 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP84383.1 - 0.0067 16.5 7.4 0.3 11.3 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat SPARC_Ca_bdg PF10591.9 PRP84383.1 - 0.0078 16.5 0.0 3.2 8.1 0.0 3.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TPR_11 PF13414.6 PRP84383.1 - 0.0084 15.8 0.4 2.9 7.6 0.1 3.3 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 PRP84383.1 - 0.021 15.6 9.7 70 4.6 0.1 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP84383.1 - 0.028 14.7 0.8 1 9.7 0.4 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4398 PF14346.6 PRP84383.1 - 0.03 14.9 0.3 14 6.4 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) UPF0154 PF03672.13 PRP84383.1 - 0.12 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) TPR_7 PF13176.6 PRP84383.1 - 0.13 12.4 0.1 0.85 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP84383.1 - 0.17 12.2 0.3 18 5.6 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PRP84383.1 - 0.18 12.5 3.2 38 5.0 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat F-box PF00646.33 PRP84384.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP84384.1 - 0.0053 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 PRP84384.1 - 0.0086 15.9 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like Mito_carr PF00153.27 PRP84385.1 - 4.9e-64 212.3 1.5 3.2e-20 71.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Plk4_PB1 PF18190.1 PRP84386.1 - 0.02 15.0 1.8 0.048 13.8 1.1 1.9 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 Pkinase PF00069.25 PRP84387.1 - 5.1e-40 137.5 0.0 6.2e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84387.1 - 1.5e-20 73.6 0.0 1.8e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP84387.1 - 1.5e-06 27.8 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP84387.1 - 0.00085 19.3 0.2 0.0027 17.7 0.2 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP84387.1 - 0.0057 15.6 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP84387.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 PRP84387.1 - 0.045 13.1 0.0 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 PRP84387.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nup35_RRM_2 PF14605.6 PRP84389.1 - 1.2e-07 31.6 0.1 1.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-4CXXC_R1 PF10497.9 PRP84389.1 - 2.1e-06 27.9 12.3 2.1e-06 27.9 12.3 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 RRM_1 PF00076.22 PRP84389.1 - 2.6e-05 23.9 0.0 7.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JmjC PF02373.22 PRP84389.1 - 0.022 15.2 0.0 0.074 13.5 0.0 1.9 1 0 0 1 1 1 0 JmjC domain, hydroxylase C1_2 PF03107.16 PRP84389.1 - 7 7.1 19.7 1.8 8.9 4.7 2.9 2 0 0 2 2 2 0 C1 domain START PF01852.19 PRP84391.1 - 0.0091 15.4 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 START domain Pkinase_Tyr PF07714.17 PRP84392.1 - 3.8e-77 259.1 0.0 5.9e-77 258.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP84392.1 - 3.1e-61 203.0 122.3 1.8e-09 37.2 1.6 21.6 8 6 17 25 25 25 21 Leucine rich repeat Pkinase PF00069.25 PRP84392.1 - 2.4e-53 181.2 0.0 1.2e-52 178.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 PRP84392.1 - 1.6e-52 174.5 121.6 0.0003 21.1 0.9 25.0 15 8 8 28 28 27 18 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP84392.1 - 7.3e-09 35.0 90.7 1.2 10.0 0.0 27.6 26 4 2 28 28 27 3 Leucine Rich Repeat LRR_9 PF14580.6 PRP84392.1 - 1.2e-06 28.1 20.3 0.00018 21.1 0.2 7.1 6 2 2 8 8 8 3 Leucine-rich repeat Pkinase_fungal PF17667.1 PRP84392.1 - 0.00044 19.2 0.1 0.00078 18.3 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase LRR_6 PF13516.6 PRP84392.1 - 0.001 18.9 124.9 2.6 8.3 0.2 29.5 33 0 0 33 33 32 6 Leucine Rich repeat Kdo PF06293.14 PRP84392.1 - 0.0014 18.0 0.4 0.0034 16.7 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRRNT_2 PF08263.12 PRP84392.1 - 0.0036 17.6 3.6 0.0036 17.6 3.6 2.5 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain START PF01852.19 PRP84392.1 - 0.0056 16.1 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 START domain Amnionless PF14828.6 PRP84392.1 - 0.19 10.5 0.1 0.34 9.7 0.1 1.3 1 0 0 1 1 1 0 Amnionless Recep_L_domain PF01030.24 PRP84392.1 - 2.1 8.5 5.0 0.98 9.6 0.0 3.1 3 0 0 3 3 3 0 Receptor L domain DUF347 PF03988.12 PRP84392.1 - 6.9 6.9 5.8 1.5 9.1 1.3 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) SMC_N PF02463.19 PRP84393.1 - 8.9e-51 172.4 61.7 4.1e-50 170.2 61.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PRP84393.1 - 2.9e-23 82.4 0.4 1.3e-22 80.3 0.4 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 PRP84393.1 - 4.7e-11 43.0 7.3 4.7e-11 43.0 7.3 4.4 2 2 2 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 PRP84393.1 - 1.6e-10 41.3 9.0 7.4e-05 22.7 0.3 3.2 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PRP84393.1 - 0.0001 22.0 0.0 0.00027 20.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP84393.1 - 0.00016 22.2 41.8 0.00016 22.2 41.8 7.8 2 2 1 3 3 3 1 AAA domain zf-C4H2 PF10146.9 PRP84393.1 - 0.0038 17.6 13.3 0.0038 17.6 13.3 7.3 3 2 2 6 6 6 1 Zinc finger-containing protein Fez1 PF06818.15 PRP84393.1 - 0.0044 17.5 12.2 0.0044 17.5 12.2 6.2 2 2 4 6 6 6 2 Fez1 DUF4092 PF13322.6 PRP84393.1 - 1.4 8.8 3.6 1 9.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4092) 2OG-FeII_Oxy_3 PF13640.6 PRP84394.1 - 2.6e-19 69.9 0.2 8.8e-19 68.2 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PRP84394.1 - 9.9e-12 45.4 0.0 1.7e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 PRP84395.1 - 4.3e-48 163.3 0.0 3.7e-26 92.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 PRP84395.1 - 8.7e-45 153.3 68.5 8.9e-23 80.9 32.5 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 PRP84395.1 - 8.4e-19 68.5 0.5 3.9e-07 30.2 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PRP84395.1 - 2.7e-07 30.6 0.0 0.41 10.3 0.0 4.2 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.19 PRP84395.1 - 0.00011 21.7 0.0 0.6 9.5 0.0 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PRP84395.1 - 0.0045 17.5 2.0 0.8 10.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 PRP84395.1 - 0.021 14.5 1.8 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 PRP84395.1 - 0.023 14.4 0.4 7.9 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 PRP84395.1 - 0.026 14.3 1.2 6.4 6.5 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_22 PF13401.6 PRP84395.1 - 0.033 14.4 0.6 10 6.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP84395.1 - 0.07 12.8 0.6 2.5 7.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 PRP84395.1 - 0.072 13.0 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 PRP84395.1 - 0.072 13.5 0.6 11 6.4 0.0 3.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 PRP84395.1 - 0.075 13.3 0.0 4.2 7.7 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 PRP84395.1 - 0.15 11.7 1.6 17 5.0 0.1 2.8 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 PRP84395.1 - 0.18 11.1 0.0 18 4.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 PRP84395.1 - 0.21 11.9 2.2 14 6.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PRP84395.1 - 0.65 10.1 1.9 74 3.5 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase RAI16-like PF10257.9 PRP84396.1 - 1.8e-53 181.7 0.0 4.2e-53 180.5 0.0 1.7 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein FAD_binding_4 PF01565.23 PRP84396.1 - 3.2e-17 62.6 0.6 5.9e-17 61.7 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain IBR PF01485.21 PRP84396.1 - 2.9e-11 43.4 31.6 7.5e-08 32.5 12.1 4.9 5 1 1 6 6 6 2 IBR domain, a half RING-finger domain HATPase_c PF02518.26 PRP84396.1 - 1.1e-09 38.8 0.0 4.3e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BBE PF08031.12 PRP84396.1 - 9.9e-08 32.0 0.6 2.5e-07 30.7 0.6 1.7 1 0 0 1 1 1 1 Berberine and berberine like zf-RING_UBOX PF13445.6 PRP84396.1 - 0.0002 21.3 6.2 0.0002 21.3 6.2 2.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PRP84396.1 - 0.00026 21.3 7.1 0.00026 21.3 7.1 3.5 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 PRP84396.1 - 0.0015 18.3 3.0 0.0015 18.3 3.0 4.1 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP84396.1 - 0.0032 17.3 3.7 0.0032 17.3 3.7 3.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP84396.1 - 0.0048 16.8 8.1 0.0048 16.8 8.1 3.6 3 0 0 3 3 1 1 zinc-RING finger domain FPL PF09758.9 PRP84396.1 - 0.012 15.6 0.0 0.043 13.8 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised conserved protein SecA_SW PF07516.13 PRP84396.1 - 0.024 14.7 0.1 0.024 14.7 0.1 2.5 3 0 0 3 3 3 0 SecA Wing and Scaffold domain RWD PF05773.22 PRP84396.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 RWD domain Cytokin-bind PF09265.10 PRP84396.1 - 0.074 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding zf-RING_11 PF17123.5 PRP84396.1 - 1.4 8.7 8.6 4.4 7.1 8.6 2.0 1 0 0 1 1 1 0 RING-like zinc finger Pkinase PF00069.25 PRP84398.1 - 9.3e-32 110.4 0.3 2.1e-31 109.3 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 PRP84398.1 - 2.6e-19 70.1 0.3 7.1e-19 68.7 0.3 1.8 1 0 0 1 1 1 1 RasGEF domain Pkinase_Tyr PF07714.17 PRP84398.1 - 5.7e-16 58.6 0.2 1.3e-15 57.4 0.2 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Rap_GAP PF02145.15 PRP84398.1 - 7.4e-14 51.7 0.0 2.6e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Rap/ran-GAP Ank PF00023.30 PRP84398.1 - 8.3e-12 45.0 0.7 0.00064 20.1 0.1 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 PRP84398.1 - 4.7e-11 42.7 1.4 1e-06 28.9 0.2 3.7 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP84398.1 - 1.5e-09 38.2 0.3 0.0007 20.1 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP84398.1 - 8.4e-09 35.9 0.3 0.0019 18.7 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP84398.1 - 2e-06 27.7 0.2 1.1 10.0 0.1 5.2 4 0 0 4 4 4 2 Ankyrin repeat SH2 PF00017.24 PRP84398.1 - 0.045 13.8 0.2 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 SH2 domain RasGEF_N PF00618.20 PRP84398.1 - 0.072 13.3 1.8 0.33 11.2 1.8 2.1 1 0 0 1 1 1 0 RasGEF N-terminal motif zf-C3Hc3H PF13891.6 PRP84399.1 - 0.00011 22.5 5.0 0.00047 20.5 4.9 2.0 1 1 0 1 1 1 1 Potential DNA-binding domain PS_Dcarbxylase PF02666.15 PRP84400.1 - 9.6e-67 224.4 0.0 1.3e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.22 PRP84400.1 - 0.064 13.5 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Peptidase family M23 DUF3899 PF13038.6 PRP84400.1 - 0.48 11.0 2.5 2.7 8.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) UCH PF00443.29 PRP84401.1 - 6.6e-56 189.7 1.4 1.5e-55 188.5 1.4 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP84401.1 - 2e-26 93.3 1.2 2e-26 93.3 1.2 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3629 PF12302.8 PRP84401.1 - 0.012 15.1 1.6 0.029 13.8 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) DUF5123 PF17161.4 PRP84402.1 - 1.1 10.3 12.9 1.9 9.6 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5123) HHH_2 PF12826.7 PRP84403.1 - 0.027 14.6 0.0 0.085 13.0 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif F-box-like PF12937.7 PRP84404.1 - 3.6e-07 30.0 0.1 9e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 PRP84404.1 - 0.00014 22.4 0.0 0.00071 20.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box_5 PF18511.1 PRP84404.1 - 0.0028 17.2 0.1 0.005 16.4 0.1 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 PRP84404.1 - 0.0066 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain Ank_3 PF13606.6 PRP84404.1 - 0.17 12.5 0.1 12 6.8 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeat Beta-lactamase PF00144.24 PRP84405.1 - 8e-34 117.3 0.0 1.7e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase TPR_2 PF07719.17 PRP84405.1 - 5.9e-06 26.0 25.4 0.12 12.5 0.0 8.0 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP84405.1 - 6.9e-06 25.7 22.8 0.0088 15.8 0.1 7.6 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP84405.1 - 0.00026 21.6 0.0 0.63 10.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP84405.1 - 0.00039 20.6 7.8 0.23 11.8 0.7 5.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP84405.1 - 0.0018 18.0 4.9 0.005 16.5 0.2 4.3 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 PRP84405.1 - 0.0021 18.2 0.2 0.0089 16.2 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP84405.1 - 0.0025 17.7 0.1 0.048 13.7 0.0 3.4 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP84405.1 - 0.18 12.1 11.6 7.6 7.0 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 PRP84405.1 - 0.2 12.3 7.8 6.1 7.7 0.1 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP84405.1 - 0.46 11.4 7.3 12 7.0 0.0 5.2 4 1 1 5 5 4 0 Tetratricopeptide repeat TAN PF11640.8 PRP84405.1 - 0.65 10.1 7.4 3.5 7.7 0.0 4.2 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair TPR_17 PF13431.6 PRP84405.1 - 3.8 8.1 7.5 22 5.7 0.1 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 PRP84406.1 - 1.6e-68 230.8 0.0 4.1e-68 229.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84406.1 - 2.5e-48 164.8 0.0 5.1e-48 163.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP84406.1 - 9.9e-05 21.8 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP84406.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PTP_tm PF18861.1 PRP84406.1 - 0.005 16.9 0.2 0.013 15.5 0.2 1.7 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Haspin_kinase PF12330.8 PRP84406.1 - 0.022 13.7 0.1 0.12 11.2 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP84406.1 - 0.072 11.9 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Syndecan PF01034.20 PRP84406.1 - 0.31 11.0 2.8 0.34 10.9 0.1 2.2 2 0 0 2 2 2 0 Syndecan domain Insulin_TMD PF17870.1 PRP84406.1 - 1.3 9.2 4.9 0.64 10.1 0.3 2.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Pkinase PF00069.25 PRP84407.1 - 7.3e-68 228.8 0.0 5.6e-44 150.5 0.2 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84407.1 - 1.3e-33 116.4 0.0 5.5e-26 91.4 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.24 PRP84407.1 - 1.2e-18 67.1 0.6 4e-18 65.4 0.6 1.9 1 0 0 1 1 1 1 PX domain PH PF00169.29 PRP84407.1 - 6.3e-17 62.0 0.1 2.2e-16 60.3 0.0 2.0 2 0 0 2 2 1 1 PH domain Kinase-like PF14531.6 PRP84407.1 - 1.2e-05 24.8 0.1 0.00029 20.2 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PRP84407.1 - 1.7e-05 24.0 0.1 3.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain PH_11 PF15413.6 PRP84407.1 - 0.0012 19.2 0.7 0.011 16.2 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain Kdo PF06293.14 PRP84407.1 - 0.0013 18.1 0.3 0.0066 15.8 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP84407.1 - 0.0043 17.0 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP84407.1 - 0.022 14.4 0.1 0.066 12.8 0.1 1.9 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 PRP84407.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 zf_C2HC_14 PF18574.1 PRP84407.1 - 1.4 8.8 4.6 2.7 7.8 0.6 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain TNFR_16_TM PF18422.1 PRP84408.1 - 0.011 15.7 0.2 0.031 14.2 0.2 1.7 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF3094 PF11293.8 PRP84408.1 - 0.1 12.3 0.8 0.21 11.3 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) MAP17 PF15807.5 PRP84408.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 OSTbeta PF15048.6 PRP84408.1 - 0.21 11.7 0.1 25 5.0 0.0 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein UQ_con PF00179.26 PRP84409.1 - 5.1e-37 126.6 0.0 6.1e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ku PF02735.16 PRP84411.1 - 1.2e-57 195.0 3.5 1.2e-57 195.0 0.0 2.4 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 PRP84411.1 - 6.3e-52 176.5 0.8 1.2e-51 175.6 0.8 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 PRP84411.1 - 2.2e-15 57.1 1.8 2.2e-15 57.1 1.8 3.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm zf-CCHH PF10283.9 PRP84411.1 - 1.8e-12 47.0 5.0 3.6e-12 46.0 5.0 1.5 1 0 0 1 1 1 1 PBZ domain HeH PF12949.7 PRP84411.1 - 2.1e-06 27.3 0.1 5.1e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 PRP84411.1 - 0.073 12.8 0.0 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 SAP domain ASF1_hist_chap PF04729.13 PRP84412.1 - 5.5e-59 198.5 0.0 6.1e-59 198.4 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone SelR PF01641.18 PRP84413.1 - 0.041 13.9 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 SelR domain MT-A70 PF05063.14 PRP84414.1 - 9.7e-12 45.1 0.4 1.9e-11 44.2 0.4 1.5 1 0 0 1 1 1 1 MT-A70 LRR_4 PF12799.7 PRP84415.1 - 0.23 12.0 15.0 26 5.4 0.2 6.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) p450 PF00067.22 PRP84416.1 - 1.2e-47 162.7 0.2 1.9e-47 162.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.6 PRP84416.1 - 3.8e-16 59.3 0.0 9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP84416.1 - 1.3e-15 57.5 0.0 4.3e-15 55.8 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PRP84416.1 - 2e-14 53.7 0.0 4.7e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP84416.1 - 2.2e-09 37.2 0.1 8.3e-09 35.3 0.1 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP84416.1 - 1.2e-08 35.0 0.0 3.9e-08 33.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP84416.1 - 0.00079 19.6 0.0 0.0025 18.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 PRP84416.1 - 0.012 16.3 0.0 0.07 13.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain GST_N_4 PF17172.4 PRP84416.1 - 0.038 14.7 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 PRP84416.1 - 0.04 14.2 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein LRV_FeS PF05484.11 PRP84416.1 - 0.08 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 LRV protein FeS4 cluster Epimerase PF01370.21 PRP84417.1 - 1.6e-17 63.8 0.1 5.1e-16 58.9 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PRP84417.1 - 1e-13 51.4 0.5 2.1e-13 50.4 0.2 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 PRP84417.1 - 1.5e-13 51.1 1.0 1.1e-12 48.3 0.2 2.2 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PRP84417.1 - 1.6e-07 30.7 0.8 6.1e-06 25.4 0.8 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PRP84417.1 - 2.5e-06 26.9 0.2 1.3e-05 24.5 0.1 2.1 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 PRP84417.1 - 2.6e-06 26.8 0.1 0.00035 19.8 0.1 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 PRP84417.1 - 5.6e-06 26.0 1.0 0.00023 20.7 0.1 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 PRP84417.1 - 0.0008 19.7 1.1 0.0023 18.2 0.2 2.2 3 0 0 3 3 3 1 TrkA-N domain adh_short PF00106.25 PRP84417.1 - 0.0029 17.1 0.2 0.019 14.4 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.20 PRP84417.1 - 0.0087 16.2 0.2 0.021 14.9 0.2 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.15 PRP84417.1 - 0.01 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 PRP84417.1 - 0.021 14.0 0.2 0.2 10.7 0.3 2.4 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein ApbA PF02558.16 PRP84417.1 - 0.039 13.6 0.1 0.098 12.3 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA KR PF08659.10 PRP84417.1 - 0.047 13.6 0.2 0.086 12.7 0.2 1.5 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 PRP84417.1 - 0.092 13.2 1.3 0.27 11.7 0.3 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Exo_endo_phos PF03372.23 PRP84418.1 - 7.5e-17 61.6 0.0 9.2e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SAP PF02037.27 PRP84418.1 - 2.9e-10 39.7 2.7 4.9e-10 38.9 2.7 1.4 1 0 0 1 1 1 1 SAP domain DUF2052 PF09747.9 PRP84418.1 - 0.0023 18.1 4.0 0.0043 17.2 4.0 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Exo_endo_phos_2 PF14529.6 PRP84418.1 - 0.0079 16.0 0.0 0.14 12.0 0.0 2.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase HeH PF12949.7 PRP84418.1 - 0.019 14.7 1.0 0.019 14.7 1.0 2.0 2 0 0 2 2 1 0 HeH/LEM domain TRAP_alpha PF03896.16 PRP84418.1 - 0.14 11.4 3.0 0.19 10.9 3.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.6 PRP84418.1 - 0.19 12.1 10.0 0.42 11.0 10.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GOLD_2 PF13897.6 PRP84418.1 - 0.55 10.7 3.6 1.4 9.4 3.6 1.7 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.14 PRP84418.1 - 0.85 7.8 6.4 1.1 7.5 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 PRP84418.1 - 0.89 9.2 6.5 1.5 8.4 6.5 1.3 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 PRP84418.1 - 1.1 7.3 5.4 1.4 6.9 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 PRP84418.1 - 1.2 7.2 9.0 2.3 6.2 8.8 1.5 2 0 0 2 2 2 0 DNA polymerase phi FAM178 PF14816.6 PRP84418.1 - 1.8 7.5 5.9 2.7 6.9 5.9 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 DUF1840 PF08895.11 PRP84418.1 - 3.6 8.0 7.0 7.1 7.0 7.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) NOA36 PF06524.12 PRP84418.1 - 7.5 5.8 8.0 11 5.2 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein E7 PF00527.18 PRP84418.1 - 7.7 6.8 7.0 16 5.8 7.0 1.5 1 0 0 1 1 1 0 E7 protein, Early protein RPN2_C PF18004.1 PRP84418.1 - 8.8 6.2 14.7 14 5.6 14.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain GEN1_C PF18380.1 PRP84418.1 - 9.4 7.2 10.6 20 6.1 10.6 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain EthD PF07110.11 PRP84420.1 - 1e-17 65.0 0.2 1.5e-17 64.5 0.2 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 PRP84420.1 - 1.1e-05 25.8 0.1 2.2e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase RhoGEF PF00621.20 PRP84422.1 - 8.6e-28 97.8 0.5 1.8e-27 96.7 0.5 1.6 1 0 0 1 1 1 1 RhoGEF domain Ank_4 PF13637.6 PRP84422.1 - 1.4e-09 38.2 0.0 0.0029 18.1 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP84422.1 - 1.5e-07 31.6 0.0 0.31 11.6 0.0 5.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 PRP84422.1 - 2e-07 31.1 0.0 0.097 13.0 0.0 4.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP84422.1 - 5.8e-07 30.0 0.0 0.0015 19.1 0.0 3.8 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP84422.1 - 7.8e-06 25.9 0.7 0.0012 19.2 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat PH PF00169.29 PRP84422.1 - 0.021 15.3 0.1 0.077 13.5 0.1 2.1 1 0 0 1 1 1 0 PH domain DNA_gyraseB PF00204.25 PRP84422.1 - 0.038 13.5 0.2 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 DNA gyrase B PH_13 PF16652.5 PRP84422.1 - 0.039 13.8 0.3 0.12 12.2 0.3 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_Tyr PF07714.17 PRP84423.1 - 1.7e-70 237.2 0.0 2.6e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84423.1 - 1.3e-47 162.3 0.0 2.3e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP84423.1 - 1.6e-34 117.4 97.2 7.8e-05 22.4 0.6 14.0 6 2 9 16 16 16 14 Leucine rich repeat LRR_4 PF12799.7 PRP84423.1 - 5e-26 90.3 108.2 2.9e-06 27.5 5.0 17.3 8 4 14 22 22 22 14 Leucine Rich repeats (2 copies) Cellulase PF00150.18 PRP84423.1 - 2.4e-16 60.0 5.0 2.4e-11 43.6 0.5 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Kinase-like PF14531.6 PRP84423.1 - 0.00097 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 PRP84423.1 - 0.0063 16.5 59.4 0.31 11.2 0.0 14.7 16 0 0 16 16 16 4 Leucine Rich repeat Pkinase_fungal PF17667.1 PRP84423.1 - 0.023 13.5 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_9 PF14580.6 PRP84423.1 - 0.16 11.4 17.8 0.045 13.2 0.7 5.0 4 1 0 4 4 4 0 Leucine-rich repeat Kdo PF06293.14 PRP84423.1 - 0.23 10.8 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.6 PRP84424.1 - 8.4e-31 105.6 10.9 1.1e-09 38.3 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP84424.1 - 9.4e-30 103.0 3.9 7.7e-10 39.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84424.1 - 7.9e-27 93.3 8.3 1.3e-09 38.4 0.1 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP84424.1 - 1.4e-22 79.0 16.2 6.7e-07 29.5 0.3 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 PRP84424.1 - 4.7e-22 75.7 5.1 8.6e-05 22.7 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ribosomal_L37e PF01907.19 PRP84425.1 - 2.7e-25 88.3 10.7 2.7e-25 88.3 10.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e DUF1462 PF07315.11 PRP84425.1 - 0.055 13.7 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) zf-RING_10 PF16685.5 PRP84425.1 - 0.11 12.6 1.4 0.15 12.2 1.4 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 Arf PF00025.21 PRP84426.1 - 1.2e-46 158.4 0.0 1.5e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PRP84426.1 - 5.9e-21 74.7 0.0 7.7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP84426.1 - 6e-17 62.0 0.0 9.2e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP84426.1 - 3.6e-12 46.1 0.0 4.6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PRP84426.1 - 7.5e-11 41.8 0.0 9.7e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP84426.1 - 1.3e-08 34.9 0.0 2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 PRP84426.1 - 3.7e-08 32.9 0.2 3e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 PRP84426.1 - 0.00011 21.8 0.0 0.0034 17.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 PRP84426.1 - 0.022 14.8 0.2 1.6 8.7 0.2 2.2 1 1 1 2 2 2 0 Dynamin family AAA_7 PF12775.7 PRP84426.1 - 0.031 13.8 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 PRP84426.1 - 0.041 13.4 0.7 0.16 11.5 0.1 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 PRP84426.1 - 0.072 12.9 0.0 2.7 7.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Pkinase PF00069.25 PRP84427.1 - 2.7e-62 210.5 0.0 5.7e-62 209.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84427.1 - 7.5e-50 169.6 0.0 1.1e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP84427.1 - 6.5e-10 38.4 0.0 1.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP84427.1 - 0.015 14.3 1.2 0.33 9.9 0.1 2.7 2 1 0 2 2 2 0 Haspin like kinase domain Troponin PF00992.20 PRP84427.1 - 0.025 14.9 2.4 0.05 13.9 2.4 1.4 1 0 0 1 1 1 0 Troponin Mst1_SARAH PF11629.8 PRP84427.1 - 0.067 13.3 2.0 0.17 12.0 2.0 1.6 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 TnpV PF14198.6 PRP84427.1 - 0.085 12.8 0.9 0.26 11.3 0.9 1.8 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Nore1-SARAH PF16517.5 PRP84427.1 - 0.26 11.2 0.2 0.26 11.2 0.2 2.3 3 0 0 3 3 3 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Hamartin PF04388.12 PRP84430.1 - 0.43 9.2 7.4 0.65 8.6 7.4 1.2 1 0 0 1 1 1 0 Hamartin protein Pkinase_Tyr PF07714.17 PRP84431.1 - 9.5e-68 228.3 0.0 1.4e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84431.1 - 3.1e-48 164.5 0.0 5e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP84431.1 - 3.3e-31 106.8 76.1 9.3e-08 31.7 0.5 12.6 10 2 2 12 12 12 9 Leucine rich repeat LRR_4 PF12799.7 PRP84431.1 - 5e-29 99.9 82.3 7.8e-06 26.1 2.3 16.3 10 4 5 17 17 17 10 Leucine Rich repeats (2 copies) Cellulase PF00150.18 PRP84431.1 - 9.9e-19 67.8 9.1 6.6e-17 61.8 8.0 2.3 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) RNase_T PF00929.24 PRP84431.1 - 1.4e-12 48.5 0.0 3.2e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Exonuclease LRR_6 PF13516.6 PRP84431.1 - 0.00025 20.8 46.1 0.46 10.7 0.0 14.8 17 0 0 17 17 17 2 Leucine Rich repeat LRR_9 PF14580.6 PRP84431.1 - 0.0068 15.9 12.8 0.28 10.6 0.4 5.2 6 0 0 6 6 6 1 Leucine-rich repeat LRR_5 PF13306.6 PRP84431.1 - 0.027 14.4 1.1 0.88 9.5 0.8 3.0 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PRP84431.1 - 0.037 14.5 63.0 13 6.8 0.2 17.9 16 5 2 18 18 18 0 Leucine Rich Repeat Kdo PF06293.14 PRP84431.1 - 0.044 13.1 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP84431.1 - 0.053 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pyrophosphatase PF00719.19 PRP84432.1 - 2.8e-48 163.8 0.4 3.3e-48 163.5 0.4 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF2156 PF09924.9 PRP84433.1 - 6.2e-07 28.7 0.0 6.6e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Peptidase_C10 PF01640.17 PRP84436.1 - 0.011 16.0 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase C10 family DUF3883 PF13020.6 PRP84437.1 - 2.6e-06 27.4 0.0 9.8e-06 25.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) CCDC-167 PF15188.6 PRP84437.1 - 1.3 9.5 6.7 17 5.9 0.0 3.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GATase_6 PF13522.6 PRP84438.1 - 2.5e-10 40.7 0.0 3.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 PRP84438.1 - 9.1e-08 31.3 0.0 1.1e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II F420H2_quin_red PF04075.14 PRP84438.1 - 0.04 14.1 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 F420H(2)-dependent quinone reductase UCH PF00443.29 PRP84441.1 - 2.9e-32 112.2 0.6 5.4e-32 111.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PRP84441.1 - 2.8e-13 50.0 0.6 2.8e-13 50.0 0.6 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein MSC PF09402.10 PRP84441.1 - 0.047 13.1 0.2 0.077 12.4 0.2 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PCI PF01399.27 PRP84442.1 - 6.9e-11 42.6 0.1 1.7e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 PCI domain Tim29 PF10171.9 PRP84442.1 - 0.023 14.2 0.5 0.058 12.9 0.1 1.9 2 0 0 2 2 2 0 Translocase of the Inner Mitochondrial membrane 29 Rpn9_C PF18261.1 PRP84442.1 - 0.024 14.2 0.3 0.049 13.2 0.3 1.6 1 0 0 1 1 1 0 Rpn9 C-terminal helix SMK-1 PF04802.15 PRP84443.1 - 2.3e-66 223.3 5.2 2.3e-66 223.3 5.2 1.9 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Cnd1_N PF12922.7 PRP84443.1 - 0.036 13.9 0.6 0.45 10.3 0.0 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Ran_BP1 PF00638.18 PRP84443.1 - 0.063 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 RanBP1 domain MRP-S23 PF10484.9 PRP84444.1 - 1.2e-08 35.2 0.1 3.2e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 IQ PF00612.27 PRP84445.1 - 8.8e-05 22.0 0.2 8.8e-05 22.0 0.2 3.1 3 0 0 3 3 3 1 IQ calmodulin-binding motif AAA PF00004.29 PRP84445.1 - 0.033 14.6 0.0 0.21 12.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GDYXXLXY PF14345.6 PRP84445.1 - 0.062 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 GDYXXLXY protein TMEM206 PF15122.6 PRP84445.1 - 0.13 11.4 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 TMEM206 protein family CDI PF02234.19 PRP84445.1 - 0.16 12.2 1.7 0.24 11.6 0.2 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor ABA_GPCR PF12430.8 PRP84446.1 - 8.6e-40 136.4 12.8 1.5e-39 135.6 12.8 1.4 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 PRP84446.1 - 4.5e-21 74.7 0.1 1.7e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal tRNA-synt_1c PF00749.21 PRP84447.1 - 2.5e-103 345.3 0.0 3.3e-103 344.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 PRP84447.1 - 1.7e-35 122.4 0.0 3.1e-35 121.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 PRP84447.1 - 0.025 14.8 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.29 PRP84448.1 - 1.1e-49 168.6 0.0 1.7e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP84448.1 - 3.2e-33 114.4 0.0 3e-31 108.1 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP84448.1 - 0.00028 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 PRP84448.1 - 0.014 14.2 0.1 0.03 13.1 0.0 1.5 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 PRP84448.1 - 0.049 13.0 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SPX PF03105.19 PRP84448.1 - 1.1 9.1 3.2 1.8 8.4 3.2 1.3 1 0 0 1 1 1 0 SPX domain DUF5327 PF17261.2 PRP84449.1 - 0.49 11.2 7.4 0.28 11.9 0.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DUF3408 PF11888.8 PRP84449.1 - 4 7.6 7.3 2.6 8.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) UTP15_C PF09384.10 PRP84450.1 - 2.6e-33 114.8 0.8 4.8e-33 113.9 0.8 1.4 1 0 0 1 1 1 1 UTP15 C terminal Frataxin_Cyay PF01491.16 PRP84450.1 - 1.2e-17 64.0 0.0 5e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 Frataxin-like domain WD40 PF00400.32 PRP84450.1 - 1.6e-15 57.2 11.1 0.00023 21.9 0.2 6.6 6 1 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84450.1 - 0.00058 20.1 0.1 0.44 10.9 0.1 4.0 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ndc80_HEC PF03801.13 PRP84451.1 - 1e-39 135.6 0.0 3.8e-39 133.8 0.0 2.0 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 PRP84451.1 - 0.037 14.1 0.1 0.037 14.1 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF5595) TM2 PF05154.16 PRP84452.1 - 4.6e-14 52.5 12.9 4.6e-14 52.5 12.9 2.0 2 0 0 2 2 2 1 TM2 domain SAC3 PF12209.8 PRP84453.1 - 0.029 14.5 8.6 0.15 12.3 1.6 3.3 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain DUF637 PF04830.13 PRP84453.1 - 0.089 12.6 0.2 4.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Possible hemagglutinin (DUF637) Pkinase_Tyr PF07714.17 PRP84455.1 - 1.1e-66 224.8 0.0 1.5e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84455.1 - 4.1e-44 150.9 0.0 6e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP84455.1 - 9.7e-34 114.9 101.0 2.9e-06 27.5 6.7 16.6 9 3 7 17 17 17 16 Leucine Rich repeats (2 copies) Cellulase PF00150.18 PRP84455.1 - 1.2e-32 113.5 6.8 2.9e-21 76.1 1.5 2.3 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) LRR_8 PF13855.6 PRP84455.1 - 6.9e-29 99.4 93.2 3e-06 26.9 9.7 13.6 6 4 6 15 15 15 9 Leucine rich repeat LRR_1 PF00560.33 PRP84455.1 - 2.6e-05 24.1 85.5 0.12 13.0 0.2 20.6 22 3 1 23 23 23 3 Leucine Rich Repeat DUF4434 PF14488.6 PRP84455.1 - 0.00051 20.1 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) LRR_6 PF13516.6 PRP84455.1 - 1.1 9.5 59.6 0.53 10.5 0.1 15.3 19 0 0 19 19 19 0 Leucine Rich repeat Tim44 PF04280.15 PRP84456.1 - 2.3e-07 31.0 0.0 5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain ApbA PF02558.16 PRP84457.1 - 4.6e-33 114.0 0.0 6.5e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 PRP84457.1 - 3.7e-22 78.8 0.0 2.6e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal zf-ribbon_3 PF13248.6 PRP84458.1 - 7.5e-05 22.0 7.0 0.00011 21.5 7.0 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 PRP84458.1 - 0.00084 19.3 1.3 0.0012 18.8 1.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 PRP84458.1 - 0.00098 18.8 10.0 0.0014 18.3 10.0 1.2 1 0 0 1 1 1 1 zinc-ribbon domain HypA PF01155.19 PRP84458.1 - 0.0049 16.9 0.6 0.0062 16.6 0.6 1.3 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_3 PF13920.6 PRP84458.1 - 0.017 15.0 3.0 0.028 14.3 3.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NRDD PF13597.6 PRP84458.1 - 0.079 11.7 1.0 0.096 11.4 1.0 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase zinc_ribbon_15 PF17032.5 PRP84458.1 - 0.75 10.6 9.4 0.57 11.0 7.8 1.5 1 1 0 2 2 2 0 zinc-ribbon family Ank_2 PF12796.7 PRP84459.1 - 9.7e-69 228.0 0.0 3.4e-09 37.2 0.0 9.1 2 2 5 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84459.1 - 5e-60 199.1 1.6 1.8e-05 25.2 0.0 14.2 6 2 9 16 16 16 14 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP84459.1 - 1.1e-41 140.4 4.9 0.063 13.6 0.0 18.0 8 4 10 18 18 18 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84459.1 - 8.6e-33 108.7 4.8 2.3 9.1 0.0 18.9 21 0 0 21 21 21 5 Ankyrin repeat Ank PF00023.30 PRP84459.1 - 4.8e-29 99.5 16.9 0.3 11.6 0.0 18.6 19 1 1 20 20 20 4 Ankyrin repeat YlzJ PF14035.6 PRP84459.1 - 8.3e-11 41.9 6.2 4.5 7.6 0.0 10.5 10 1 2 12 12 12 3 YlzJ-like protein DUF3734 PF12536.8 PRP84459.1 - 0.006 16.9 0.1 13 6.1 0.0 5.0 5 1 1 6 6 5 1 Patatin phospholipase Hairy_orange PF07527.13 PRP84459.1 - 0.0097 16.1 8.3 2.4e+02 2.0 0.0 9.4 12 0 0 12 12 12 0 Hairy Orange Secretogranin_V PF05281.11 PRP84459.1 - 0.011 15.4 0.1 98 2.4 0.0 5.2 3 3 4 7 7 7 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) ADSL_C PF10397.9 PRP84459.1 - 0.02 15.5 2.4 1.5e+02 3.0 0.0 6.0 6 2 2 8 8 6 0 Adenylosuccinate lyase C-terminus DUF3051 PF11252.8 PRP84459.1 - 0.066 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3051) Pfg27 PF09216.10 PRP84459.1 - 0.12 12.2 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Pfg27 DUF3447 PF11929.8 PRP84459.1 - 0.13 12.3 0.0 35 4.5 0.0 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3447) Homeodomain PF00046.29 PRP84460.1 - 0.0015 18.3 6.7 0.021 14.7 0.2 2.5 1 1 1 2 2 2 2 Homeodomain SMC_N PF02463.19 PRP84462.1 - 5.9e-46 156.7 57.8 2.8e-45 154.4 57.8 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PRP84462.1 - 9.2e-25 87.2 0.0 2.5e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PRP84462.1 - 8.1e-11 42.3 0.1 6.8e-07 29.4 0.0 4.3 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PRP84462.1 - 3.7e-08 33.5 14.4 3.7e-08 33.5 14.4 4.4 2 2 2 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 PRP84462.1 - 0.0003 21.4 49.6 0.0003 21.4 49.6 7.2 2 2 1 4 4 4 1 AAA domain AAA_29 PF13555.6 PRP84462.1 - 0.14 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PRP84462.1 - 0.56 10.7 0.0 0.35 11.4 1.0 7.2 4 3 1 5 5 5 0 ABC transporter Sel1 PF08238.12 PRP84463.1 - 1.5e-10 41.4 0.0 3e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Sel1 repeat PQ-loop PF04193.14 PRP84464.1 - 4.7e-37 125.6 16.1 1.5e-19 69.5 1.4 3.0 3 0 0 3 3 3 2 PQ loop repeat Spore_III_AB PF09548.10 PRP84464.1 - 0.16 12.1 0.2 0.23 11.6 0.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Phage_holin_3_6 PF07332.11 PRP84464.1 - 0.2 11.7 0.7 0.47 10.5 0.7 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III XhlA PF10779.9 PRP84464.1 - 0.33 11.2 2.9 0.65 10.2 2.9 1.5 1 0 0 1 1 1 0 Haemolysin XhlA DUF3792 PF12670.7 PRP84464.1 - 2.7 8.2 12.3 6.4 7.0 11.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) Noc2 PF03715.13 PRP84465.1 - 1e-83 281.0 13.9 1.9e-83 280.2 13.9 1.5 1 0 0 1 1 1 1 Noc2p family Peptidase_C26 PF07722.13 PRP84466.1 - 1.3e-17 64.2 0.0 5.2e-17 62.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 PRP84466.1 - 6e-05 22.9 0.0 0.00017 21.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I EF-hand_1 PF00036.32 PRP84467.1 - 4.3e-19 66.6 12.8 9.6e-06 24.8 0.4 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PRP84467.1 - 1.1e-16 59.2 11.0 0.00014 21.5 0.7 4.5 4 0 0 4 4 4 3 EF-hand domain Acyltransferase PF01553.21 PRP84467.1 - 1.4e-15 57.1 0.0 4.1e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase EF-hand_5 PF13202.6 PRP84467.1 - 1.6e-15 55.8 15.2 1.3e-06 27.6 0.6 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PRP84467.1 - 2.8e-15 56.5 9.4 8.2e-09 35.8 2.6 2.7 2 0 0 2 2 2 2 EF-hand domain pair Cytochrom_B561 PF03188.16 PRP84467.1 - 3.1e-13 50.0 9.4 3.1e-13 50.0 9.4 2.5 3 1 0 3 3 3 1 Eukaryotic cytochrome b561 EF-hand_8 PF13833.6 PRP84467.1 - 2.9e-10 39.8 14.9 1e-06 28.5 3.2 3.9 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP84467.1 - 0.00037 20.8 0.2 0.009 16.3 0.1 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF4079 PF13301.6 PRP84467.1 - 0.0028 17.8 11.1 0.022 14.9 1.4 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF4079) EF-hand_9 PF14658.6 PRP84467.1 - 0.068 13.5 0.2 0.49 10.8 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain EF-hand_4 PF12763.7 PRP84467.1 - 0.37 10.8 3.1 1.1 9.2 0.4 2.8 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand RasGAP PF00616.19 PRP84468.1 - 3e-12 46.7 0.2 2.5e-11 43.7 0.2 2.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 PRP84468.1 - 4.5e-08 33.3 0.1 2.8e-07 30.7 0.1 2.5 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ASH PF15780.5 PRP84469.1 - 0.00041 20.5 0.2 4.4 7.6 0.0 4.8 5 1 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin WD40 PF00400.32 PRP84470.1 - 1.3e-09 38.5 4.9 0.0046 17.8 0.0 6.4 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84470.1 - 7.3e-06 26.2 0.6 1.2 9.5 0.0 4.5 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP84470.1 - 0.00081 18.4 0.0 0.32 9.9 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 PRP84470.1 - 0.0015 18.2 0.0 0.0077 15.8 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.11 PRP84470.1 - 0.11 11.3 0.0 6.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like DUF727 PF05303.12 PRP84471.1 - 0.025 14.6 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF727) DIOX_N PF14226.6 PRP84471.1 - 0.12 13.1 0.1 0.27 12.0 0.1 1.5 1 1 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal zf-ribbon_3 PF13248.6 PRP84471.1 - 1.4 8.4 4.3 0.54 9.7 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Colicin_V PF02674.16 PRP84472.1 - 0.056 13.4 0.1 0.056 13.4 0.1 1.8 2 0 0 2 2 2 0 Colicin V production protein Pox_A14 PF05767.12 PRP84472.1 - 0.2 11.8 4.9 3.1 8.0 0.1 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Phage_holin_3_6 PF07332.11 PRP84472.1 - 1 9.4 5.4 0.81 9.7 0.3 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SH3_1 PF00018.28 PRP84473.1 - 3.8e-07 29.6 0.7 2.5e-06 27.0 0.3 2.4 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 PRP84473.1 - 5.8e-05 22.7 0.1 0.00018 21.1 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 PRP84473.1 - 0.00015 21.5 0.1 0.00041 20.2 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain COG5 PF10392.9 PRP84475.1 - 1.9e-20 73.4 7.2 1.9e-20 73.4 7.2 3.4 4 0 0 4 4 4 1 Golgi transport complex subunit 5 COG2 PF06148.11 PRP84475.1 - 4.3e-05 23.6 1.7 4.3e-05 23.6 1.7 2.7 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 PRP84475.1 - 0.0001 21.7 4.1 0.00032 20.1 4.1 1.9 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Vps51 PF08700.11 PRP84475.1 - 0.0015 18.5 1.4 0.0015 18.5 1.4 3.2 4 0 0 4 4 3 1 Vps51/Vps67 ApoC-I PF04691.12 PRP84475.1 - 0.024 14.5 2.5 0.048 13.6 0.0 2.8 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) Baculo_PEP_C PF04513.12 PRP84475.1 - 0.089 12.8 8.3 2 8.4 1.1 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Suppressor_APC PF11414.8 PRP84475.1 - 0.11 12.6 3.2 1 9.4 0.2 3.5 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Apolipoprotein PF01442.18 PRP84475.1 - 0.14 12.0 6.2 0.67 9.8 1.4 3.6 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 PRP84475.1 - 0.33 11.1 9.7 0.21 11.8 0.4 4.4 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.15 PRP84475.1 - 0.52 10.4 4.3 0.26 11.4 1.1 2.2 2 0 0 2 2 1 0 RasGAP C-terminus ApoLp-III PF07464.11 PRP84475.1 - 1.8 8.6 9.8 1.9 8.6 2.0 4.0 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Com_YlbF PF06133.11 PRP84475.1 - 1.9 9.2 4.6 8.1 7.1 0.1 2.9 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA DUF489 PF04356.12 PRP84475.1 - 1.9 8.4 7.4 20 5.2 0.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF489) CLZ PF16526.5 PRP84475.1 - 2.6 8.5 12.9 2.9 8.3 0.3 5.5 4 1 2 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Laminin_II PF06009.12 PRP84475.1 - 5.4 7.0 10.8 0.98 9.4 2.3 3.7 4 0 0 4 4 4 0 Laminin Domain II Thiolase_N PF00108.23 PRP84476.1 - 2.9e-80 269.4 4.4 5.4e-80 268.5 4.4 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PRP84476.1 - 4.4e-50 168.5 0.1 9.7e-50 167.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PRP84476.1 - 0.00024 20.7 0.4 0.0066 16.1 0.0 2.9 4 0 0 4 4 4 1 Beta-ketoacyl synthase, N-terminal domain BID PF06393.11 PRP84476.1 - 0.0029 17.2 0.5 0.0056 16.2 0.5 1.4 1 0 0 1 1 1 1 BH3 interacting domain (BID) EMC3_TMCO1 PF01956.16 PRP84476.1 - 0.012 15.3 0.4 0.029 14.1 0.4 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF1676 PF07898.13 PRP84476.1 - 0.065 13.3 0.6 0.13 12.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF775 PF05603.12 PRP84476.1 - 0.11 12.0 0.8 0.45 10.0 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF775) CUE PF02845.16 PRP84477.1 - 1.1e-06 28.2 0.5 0.00037 20.1 0.0 3.2 3 0 0 3 3 3 2 CUE domain FtsJ PF01728.19 PRP84478.1 - 5e-55 186.3 0.0 9.1e-55 185.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 PRP84478.1 - 9.7e-51 172.4 39.7 9.7e-51 172.4 39.7 4.6 3 2 2 5 5 5 1 Spb1 C-terminal domain DUF3381 PF11861.8 PRP84478.1 - 9e-33 113.4 17.6 9e-33 113.4 17.6 5.6 4 2 0 4 4 4 1 Domain of unknown function (DUF3381) Acetyltransf_1 PF00583.25 PRP84479.1 - 8.2e-10 39.0 0.0 1e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP84479.1 - 3.7e-08 33.4 0.0 4.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP84479.1 - 3.2e-06 27.5 0.0 5.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP84479.1 - 0.00051 19.9 0.0 0.0016 18.4 0.0 1.6 1 1 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.7 PRP84479.1 - 0.0095 16.1 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CotJB PF12652.7 PRP84479.1 - 0.072 13.3 0.1 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 CotJB protein Carb_bind PF10645.9 PRP84481.1 - 2.4 8.4 7.9 4.4 7.6 6.6 2.2 1 1 1 2 2 2 0 Carbohydrate binding Pkinase PF00069.25 PRP84482.1 - 1.6e-45 155.5 0.0 1.9e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84482.1 - 7.4e-26 91.0 0.0 9.3e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP84482.1 - 9.4e-06 25.7 0.2 1.8e-05 24.8 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP84482.1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP84482.1 - 0.0034 16.2 0.0 0.0056 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP84482.1 - 0.027 13.4 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 PRP84482.1 - 0.06 12.7 0.2 0.34 10.2 0.0 2.2 2 1 0 2 2 2 0 Kinase-like Proteasome PF00227.26 PRP84483.1 - 6.6e-47 159.5 0.2 7.5e-47 159.3 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Neurensin PF14927.6 PRP84484.1 - 0.023 14.4 0.1 4.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Neurensin PIRT PF15099.6 PRP84484.1 - 0.098 12.2 0.0 0.098 12.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family SepZ PF06066.11 PRP84484.1 - 0.29 11.4 5.4 0.91 9.8 0.4 2.6 2 1 0 2 2 2 0 SepZ DUF3185 PF11381.8 PRP84484.1 - 0.75 9.9 7.9 1.8 8.6 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) AA_kinase PF00696.28 PRP84486.1 - 0.033 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Amino acid kinase family Pkinase PF00069.25 PRP84487.1 - 6.7e-58 196.1 0.0 2.9e-55 187.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84487.1 - 7.8e-32 110.6 0.0 3.7e-24 85.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP84487.1 - 0.00015 21.2 0.0 0.0005 19.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP84487.1 - 0.0079 15.2 0.2 0.031 13.2 0.0 1.9 1 1 1 2 2 2 1 Haspin like kinase domain APH PF01636.23 PRP84487.1 - 0.027 14.4 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP84487.1 - 0.034 12.9 0.0 0.22 10.3 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Seadorna_VP7 PF07387.11 PRP84487.1 - 0.059 12.4 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3552 PF12072.8 PRP84487.1 - 4.6 6.6 15.2 0.034 13.6 7.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF5127 PF17168.4 PRP84488.1 - 3.5e-50 170.9 4.5 5.3e-50 170.3 4.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 PRP84488.1 - 1.3e-45 155.2 2.1 4.6e-41 140.4 0.2 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4965) DUF1793 PF08760.11 PRP84488.1 - 3.1e-35 122.1 5.6 3.1e-35 122.1 5.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 PRP84488.1 - 7.2e-21 73.5 0.0 2.2e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) PAN_4 PF14295.6 PRP84488.1 - 3.7e-11 42.8 4.2 8.7e-11 41.6 4.2 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PRP84488.1 - 0.0014 18.5 0.9 0.0029 17.5 0.9 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP84488.1 - 0.0069 16.5 2.0 0.015 15.4 2.0 1.5 1 0 0 1 1 1 1 PAN-like domain PAN_3 PF08277.12 PRP84488.1 - 0.018 14.8 1.2 0.042 13.7 1.2 1.5 1 0 0 1 1 1 0 PAN-like domain DUF2053 PF09767.9 PRP84489.1 - 2.5e-39 135.0 1.0 3.8e-39 134.4 1.0 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) TPT PF03151.16 PRP84490.1 - 5.6e-21 75.2 25.5 7.5e-21 74.7 25.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PRP84490.1 - 8.3e-06 25.2 29.7 1.6e-05 24.3 29.4 1.6 1 1 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 PRP84490.1 - 0.21 11.1 23.8 5.7 6.4 23.8 2.1 1 1 0 1 1 1 0 Solute carrier family 35 DUF2254 PF10011.9 PRP84491.1 - 0.00021 20.3 7.4 0.00036 19.5 7.2 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2254) DASH_Dad3 PF08656.10 PRP84491.1 - 0.0038 17.3 0.1 0.029 14.4 0.0 2.2 2 0 0 2 2 2 1 DASH complex subunit Dad3 Carb_anhydrase PF00194.21 PRP84491.1 - 0.22 11.0 1.7 0.41 10.1 0.3 2.0 2 0 0 2 2 2 0 Eukaryotic-type carbonic anhydrase Bacteriocin_IId PF09221.10 PRP84492.1 - 3 8.1 5.4 0.61 10.3 0.9 2.2 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Dimer_Tnp_hAT PF05699.14 PRP84493.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Gp_dh_C PF02800.20 PRP84498.1 - 1.2e-71 239.4 0.0 1.9e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PRP84498.1 - 5.2e-36 123.0 0.1 1.1e-35 122.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 PRP84498.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 PRP84498.1 - 0.0092 16.1 0.1 0.031 14.4 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Peptidase_M28 PF04389.17 PRP84499.1 - 4e-26 91.9 0.0 8.9e-26 90.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 PRP84499.1 - 8.9e-18 64.5 0.0 1.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 PRP84499.1 - 1.7e-06 27.9 0.0 5.5e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 PRP84499.1 - 8.7e-05 22.3 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 PRP84499.1 - 0.0041 16.6 0.3 0.0077 15.7 0.0 1.5 2 0 0 2 2 2 1 Nicastrin Pkinase_Tyr PF07714.17 PRP84500.1 - 5.7e-65 219.2 0.0 4.9e-64 216.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84500.1 - 8e-49 166.4 0.0 1.9e-48 165.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP84500.1 - 2.3e-34 116.8 96.2 4.2e-05 23.8 1.4 16.9 14 3 3 17 17 17 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP84500.1 - 3.3e-32 110.1 98.1 5e-08 32.6 1.4 14.7 12 3 4 16 16 16 7 Leucine rich repeat Kinase-like PF14531.6 PRP84500.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP84500.1 - 0.0076 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP84500.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_5 PF13306.6 PRP84500.1 - 0.046 13.7 2.0 4.5 7.2 0.7 3.9 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) APH PF01636.23 PRP84500.1 - 0.2 11.5 0.6 3.7 7.4 0.3 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family LRR_9 PF14580.6 PRP84500.1 - 3.2 7.2 17.8 1.5 8.3 0.9 4.9 3 2 1 5 5 5 0 Leucine-rich repeat RBFA PF02033.18 PRP84501.1 - 2.7e-06 27.8 0.2 8.2e-06 26.2 0.2 1.8 1 0 0 1 1 1 1 Ribosome-binding factor A DUF4530 PF15039.6 PRP84501.1 - 0.23 11.6 0.1 0.23 11.6 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) PBP1_TM PF14812.6 PRP84501.1 - 0.37 11.2 8.2 1.8 9.0 8.2 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fz PF01392.22 PRP84502.1 - 0.0093 16.6 6.0 0.0093 16.6 6.0 1.5 1 1 0 1 1 1 1 Fz domain HIT PF01230.23 PRP84503.1 - 8.9e-22 77.7 0.0 1.3e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PRP84503.1 - 0.00017 22.0 0.0 0.00027 21.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 PRP84503.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain MFS_1 PF07690.16 PRP84504.1 - 7.8e-36 123.7 37.2 7.8e-36 123.7 37.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OAD_gamma PF04277.13 PRP84504.1 - 0.18 12.4 0.2 0.69 10.5 0.2 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Alg6_Alg8 PF03155.15 PRP84505.1 - 3.6e-164 547.3 29.1 4.2e-164 547.1 29.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family PI-PLC-X PF00388.19 PRP84506.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glyco_hydro_38N PF01074.22 PRP84508.1 - 1.6e-82 277.2 9.5 2.3e-82 276.6 9.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP84508.1 - 3e-20 73.2 0.0 1.1e-19 71.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP84508.1 - 3e-16 59.4 0.2 6.5e-16 58.3 0.2 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_57 PF03065.15 PRP84508.1 - 0.014 14.6 0.1 0.037 13.2 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Glyco_hydro38C2 PF17677.1 PRP84508.1 - 0.017 15.3 0.0 0.054 13.6 0.0 2.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Ten1_2 PF15490.6 PRP84510.1 - 1.5e-23 82.8 0.0 1.7e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 PRP84510.1 - 0.00038 20.8 0.0 0.00048 20.4 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 PRP84510.1 - 0.056 13.4 0.0 0.072 13.0 0.0 1.4 1 1 0 1 1 1 0 Telomere capping, CST complex subunit MT-A70 PF05063.14 PRP84511.1 - 3.9e-09 36.7 0.5 3.9e-09 36.7 0.5 1.6 2 0 0 2 2 2 1 MT-A70 RNA_pol PF00940.19 PRP84512.1 - 1.4e-160 534.7 0.0 3.5e-160 533.4 0.0 1.6 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 PRP84512.1 - 4.6e-30 105.2 0.8 1.1e-27 97.3 0.8 2.3 1 1 0 1 1 1 1 DNA-directed RNA polymerase N-terminal NGP1NT PF08153.12 PRP84513.1 - 9.4e-43 145.5 5.0 2.7e-42 144.0 5.0 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 PRP84513.1 - 1.3e-17 63.9 0.2 2.2e-14 53.5 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP84513.1 - 8.3e-06 25.4 0.1 0.0002 21.0 0.1 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP84513.1 - 1.4e-05 25.1 0.0 3.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 PRP84513.1 - 0.00016 21.2 0.1 0.2 11.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP84513.1 - 0.015 14.9 3.1 0.14 11.6 0.0 3.4 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Copine PF07002.16 PRP84513.1 - 0.04 13.4 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Copine zf-CCCH PF00642.24 PRP84517.1 - 1.8e-10 40.5 15.0 2.2e-05 24.3 3.9 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 PRP84517.1 - 6.3e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 PRP84517.1 - 0.00076 20.1 2.5 0.063 14.0 0.2 2.4 2 0 0 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 PRP84517.1 - 0.0017 18.4 13.0 0.0078 16.2 2.2 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 PRP84517.1 - 0.0019 18.4 2.4 0.16 12.2 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger containing family Nup35_RRM_2 PF14605.6 PRP84517.1 - 0.054 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 PRP84517.1 - 4 7.3 14.9 0.39 10.6 5.0 2.7 2 1 0 2 2 2 0 CCCH-type zinc finger RasGAP PF00616.19 PRP84518.1 - 4.3e-18 65.8 0.1 7.7e-13 48.6 0.1 4.7 3 2 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase KASH_CCD PF14662.6 PRP84518.1 - 0.0022 17.9 13.4 0.14 12.0 0.8 2.6 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH PHC2_SAM_assoc PF16616.5 PRP84518.1 - 0.0027 18.5 4.6 0.0027 18.5 4.6 2.1 2 0 0 2 2 2 1 Unstructured region on Polyhomeotic-like protein 1 and 2 TMCO5 PF14992.6 PRP84518.1 - 0.0031 17.1 13.6 0.0031 17.1 13.6 1.5 2 0 0 2 2 2 1 TMCO5 family HALZ PF02183.18 PRP84518.1 - 0.23 11.7 7.4 0.72 10.1 0.8 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Ribosomal_L5_C PF00673.21 PRP84519.1 - 9.5e-20 70.6 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 PRP84519.1 - 2.4e-19 69.4 0.5 5.7e-19 68.2 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 PRP84519.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain MPLKIP PF15502.6 PRP84520.1 - 0.025 14.8 2.4 0.034 14.4 0.2 2.5 2 0 0 2 2 2 0 M-phase-specific PLK1-interacting protein SPECT1 PF18680.1 PRP84520.1 - 0.042 13.5 1.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Plasmodium host cell traversal SPECT1 DELLA PF12041.8 PRP84520.1 - 0.2 11.5 1.6 6.9 6.6 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Nucleo_P87 PF07267.11 PRP84520.1 - 5.3 5.8 22.7 13 4.5 22.7 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DAO PF01266.24 PRP84521.1 - 6.5e-50 170.7 0.1 1.3e-49 169.7 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Rieske PF00355.26 PRP84521.1 - 8.4e-11 41.7 0.1 1.7e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.6 PRP84521.1 - 3e-06 27.4 1.0 2.7e-05 24.3 1.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PRP84521.1 - 3.7e-06 26.5 0.1 6.4e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP84521.1 - 5e-06 26.0 0.5 0.00053 19.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP84521.1 - 9.4e-06 24.9 0.7 9.4e-06 24.9 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 PRP84521.1 - 4.1e-05 22.9 2.8 9.7e-05 21.7 0.1 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 PRP84521.1 - 6.4e-05 22.2 0.8 0.00015 21.0 0.2 2.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PRP84521.1 - 7.9e-05 22.0 0.3 0.029 13.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PRP84521.1 - 0.00042 19.7 1.9 0.00056 19.3 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 PRP84521.1 - 0.00094 18.0 3.7 0.0055 15.5 1.0 2.2 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PRP84521.1 - 0.0013 18.1 0.9 0.0078 15.5 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 PRP84521.1 - 0.044 13.7 0.1 0.29 11.0 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 PRP84521.1 - 0.046 14.3 7.6 0.23 12.1 1.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PRP84521.1 - 0.062 12.1 1.1 0.1 11.4 1.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase CbiK PF06180.11 PRP84521.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Amino_oxidase PF01593.24 PRP84521.1 - 0.077 12.3 1.7 0.92 8.7 0.4 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 PRP84521.1 - 0.091 11.8 0.1 0.69 8.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pkinase_Tyr PF07714.17 PRP84522.1 - 8.8e-27 94.0 0.2 1.3e-26 93.5 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP84522.1 - 1.1e-24 85.9 57.2 3.9e-12 45.7 9.1 6.6 4 2 2 6 6 6 6 Leucine rich repeat Pkinase PF00069.25 PRP84522.1 - 1.7e-21 76.8 0.5 2.4e-21 76.3 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP84522.1 - 5.1e-20 71.2 59.1 5.5e-08 33.0 6.7 9.0 5 2 4 10 10 10 9 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP84522.1 - 1.7e-09 38.0 0.9 4.1e-09 36.8 0.9 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP84522.1 - 0.0012 19.1 54.1 0.017 15.6 0.7 11.8 10 4 0 10 10 10 4 Leucine Rich Repeat AA_permease_N PF08403.10 PRP84522.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal adh_short PF00106.25 PRP84523.1 - 2.3e-22 79.4 0.0 3.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP84523.1 - 2.1e-17 63.5 0.1 4.9e-17 62.3 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP84523.1 - 1.2e-06 28.6 0.1 0.00053 20.0 0.0 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 PRP84523.1 - 3.2e-05 23.5 0.1 0.021 14.3 0.0 2.4 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP84523.1 - 9.9e-05 21.9 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PRP84523.1 - 0.0001 22.3 0.5 0.00014 21.8 0.5 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Mfa_like_2 PF15415.6 PRP84523.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Fimbrillin-like USP19_linker PF16602.5 PRP84523.1 - 0.2 12.2 0.0 0.35 11.4 0.0 1.3 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase RIBIOP_C PF04950.12 PRP84524.1 - 1.1e-85 287.7 0.2 1.1e-85 287.7 0.2 2.6 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PRP84524.1 - 1.4e-29 102.0 0.0 8.1e-29 99.6 0.0 2.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MMR_HSR1 PF01926.23 PRP84524.1 - 0.00099 19.2 0.0 0.0092 16.1 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP84524.1 - 0.0021 17.6 3.0 0.012 15.2 0.0 3.4 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 PRP84524.1 - 0.0065 16.6 0.1 0.031 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 PRP84524.1 - 0.007 16.1 0.0 0.035 13.9 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PRP84524.1 - 0.014 15.6 0.0 0.044 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PRP84524.1 - 0.017 15.5 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 PRP84524.1 - 0.073 13.5 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PRP84524.1 - 1.6 9.2 0.0 1.6 9.2 0.0 3.0 3 1 0 3 3 3 0 ABC transporter Nop PF01798.18 PRP84525.1 - 8e-86 287.2 0.4 8e-86 287.2 0.4 2.5 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin XPG_I PF00867.18 PRP84525.1 - 5.5e-26 90.8 0.0 5.5e-26 90.8 0.0 4.0 4 1 0 4 4 4 1 XPG I-region XPG_N PF00752.17 PRP84525.1 - 5e-20 71.9 0.1 5.1e-19 68.6 0.0 2.9 2 0 0 2 2 2 1 XPG N-terminal domain NOP5NT PF08156.13 PRP84525.1 - 7.3e-17 61.5 2.4 6.4e-16 58.5 2.4 2.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Borrelia_P83 PF05262.11 PRP84525.1 - 0.001 17.7 12.2 0.001 17.7 12.2 4.1 4 0 0 4 4 4 1 Borrelia P83/100 protein RNA_pol_Rpc4 PF05132.14 PRP84525.1 - 0.0087 16.5 7.8 0.0087 16.5 7.8 7.0 6 2 2 8 8 8 1 RNA polymerase III RPC4 PGM_PMM_I PF02878.16 PRP84526.1 - 3.4e-31 107.8 0.0 9.4e-31 106.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 PRP84526.1 - 1.6e-24 86.5 0.0 4.2e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 PRP84526.1 - 2.1e-18 66.6 0.2 3.8e-18 65.7 0.2 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 PRP84526.1 - 1.1e-05 25.5 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain YitT_membrane PF02588.15 PRP84527.1 - 0.001 18.5 0.3 0.0041 16.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised 5xTM membrane BCR, YitT family COG1284 Homeodomain PF00046.29 PRP84528.1 - 2.8e-10 39.9 7.1 0.00027 20.7 2.5 3.2 4 0 0 4 4 4 2 Homeodomain YdaS_antitoxin PF15943.5 PRP84528.1 - 0.0084 16.0 0.1 2.4 8.1 0.0 2.9 3 0 0 3 3 3 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT F-box-like PF12937.7 PRP84529.1 - 2.1e-10 40.3 0.1 3.9e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like SPRY PF00622.28 PRP84529.1 - 2.4e-10 40.6 0.0 7.7e-10 38.9 0.0 1.9 1 1 0 1 1 1 1 SPRY domain F-box PF00646.33 PRP84529.1 - 2.2e-05 24.2 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF1825 PF08855.10 PRP84529.1 - 0.12 12.3 0.3 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Pkinase_Tyr PF07714.17 PRP84531.1 - 2.7e-70 236.6 0.1 8.6e-69 231.7 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84531.1 - 1.2e-50 172.3 0.0 2.2e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP84531.1 - 2.7e-29 100.7 68.4 0.00031 21.1 1.9 12.2 7 2 5 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP84531.1 - 8.1e-22 76.8 69.9 1.1e-05 25.1 3.9 10.3 4 3 7 11 11 11 9 Leucine rich repeat Kdo PF06293.14 PRP84531.1 - 0.00023 20.6 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 PRP84531.1 - 0.00042 20.1 55.1 6.8 7.0 0.0 15.2 17 0 0 17 17 16 2 Leucine Rich repeat LRR_1 PF00560.33 PRP84531.1 - 0.0036 17.7 39.6 17 6.4 0.1 14.4 12 3 1 13 13 12 0 Leucine Rich Repeat Amnionless PF14828.6 PRP84531.1 - 0.0079 15.1 0.3 0.016 14.1 0.3 1.4 1 0 0 1 1 1 1 Amnionless LRR_9 PF14580.6 PRP84531.1 - 0.029 13.9 21.1 0.32 10.5 1.0 5.1 1 1 4 5 5 5 0 Leucine-rich repeat Pkinase_fungal PF17667.1 PRP84531.1 - 0.065 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 PRP84531.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SKG6 PF08693.10 PRP84531.1 - 0.16 11.4 6.3 0.38 10.2 6.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PRP84531.1 - 0.18 12.7 0.7 0.4 11.6 0.7 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 PRP84531.1 - 0.89 9.7 4.3 2.8 8.1 4.3 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pentapeptide_4 PF13599.6 PRP84531.1 - 4.3 7.6 13.3 11 6.3 0.5 6.0 7 1 0 7 7 6 0 Pentapeptide repeats (9 copies) Syndecan PF01034.20 PRP84531.1 - 4.7 7.2 4.6 10 6.1 4.6 1.5 1 0 0 1 1 1 0 Syndecan domain Pkinase_Tyr PF07714.17 PRP84532.1 - 9.4e-74 248.0 0.0 1.9e-73 246.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84532.1 - 1.5e-52 178.6 0.0 4.1e-52 177.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain PHD PF00628.29 PRP84532.1 - 2.7e-31 107.2 40.5 1.5e-11 44.0 6.9 3.9 4 0 0 4 4 4 3 PHD-finger LRR_4 PF12799.7 PRP84532.1 - 2.1e-28 97.9 106.0 2.1e-05 24.8 3.8 13.2 5 3 10 15 15 15 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP84532.1 - 5.4e-27 93.3 94.8 8.1e-05 22.3 3.2 11.2 5 3 5 11 11 11 9 Leucine rich repeat zf-HC5HC2H PF13771.6 PRP84532.1 - 2.6e-05 24.4 20.5 0.13 12.6 0.7 3.8 3 0 0 3 3 3 3 PHD-like zinc-binding domain Kdo PF06293.14 PRP84532.1 - 0.00035 20.0 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP84532.1 - 0.0025 17.4 0.1 7.8 6.0 0.0 3.7 3 0 0 3 3 3 2 RIO1 family LRR_9 PF14580.6 PRP84532.1 - 0.011 15.2 30.4 0.046 13.2 0.8 5.7 2 1 3 5 5 5 0 Leucine-rich repeat Kinase-like PF14531.6 PRP84532.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-HC5HC2H_2 PF13832.6 PRP84532.1 - 0.16 12.1 21.6 1.8 8.7 3.5 3.6 2 1 1 3 3 3 0 PHD-zinc-finger like domain C1_2 PF03107.16 PRP84532.1 - 1.7 9.0 38.6 0.067 13.5 3.9 5.1 5 0 0 5 5 5 0 C1 domain MA3 PF02847.17 PRP84533.1 - 1.1e-27 96.3 0.8 2.4e-27 95.2 0.8 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 PRP84533.1 - 3.1e-16 59.7 0.7 9.4e-16 58.1 0.7 1.9 1 0 0 1 1 1 1 MIF4G domain MID_MedPIWI PF18296.1 PRP84533.1 - 0.061 13.1 0.1 0.17 11.6 0.0 1.8 2 1 0 2 2 2 0 MID domain of medPIWI MutL PF13941.6 PRP84533.1 - 0.088 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 MutL protein SR-25 PF10500.9 PRP84533.1 - 0.32 10.6 21.2 0.5 9.9 21.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ECH_2 PF16113.5 PRP84534.1 - 4.5e-101 338.7 0.0 5.2e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PRP84534.1 - 2.8e-22 79.2 0.0 9.3e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Malate_synthase PF01274.22 PRP84535.1 - 8.7e-203 674.3 0.0 9.9e-203 674.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Lactamase_B_2 PF12706.7 PRP84536.1 - 4.8e-10 39.3 0.0 0.00021 20.8 0.0 2.8 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP84536.1 - 3.2e-09 37.1 0.0 1.2e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 PRP84536.1 - 2.7e-07 30.2 0.0 7.5e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 tRNase Z endonuclease B_lectin PF01453.24 PRP84537.1 - 0.015 15.9 0.0 6.4 7.4 0.0 2.6 1 1 1 2 2 2 0 D-mannose binding lectin MBG PF17883.1 PRP84537.1 - 0.025 15.1 0.0 0.058 14.0 0.0 1.5 1 0 0 1 1 1 0 MBG domain PAN_4 PF14295.6 PRP84539.1 - 3.9e-19 68.3 59.5 3e-06 27.0 3.9 5.5 6 0 0 6 6 6 4 PAN domain PAN_1 PF00024.26 PRP84539.1 - 1.1e-18 66.9 25.6 0.00022 21.1 2.1 4.5 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 PRP84539.1 - 9e-07 28.9 35.1 0.035 14.2 0.9 4.7 4 0 0 4 4 4 4 PAN-like domain MBG PF17883.1 PRP84539.1 - 8.6e-06 26.3 0.1 0.26 11.9 0.0 2.7 2 0 0 2 2 2 2 MBG domain B_lectin PF01453.24 PRP84539.1 - 0.00013 22.4 0.1 10 6.7 0.0 4.3 2 2 2 4 4 4 1 D-mannose binding lectin PAN_3 PF08277.12 PRP84539.1 - 0.31 10.9 28.3 1.5 8.7 2.4 4.6 4 0 0 4 4 4 0 PAN-like domain BES1_N PF05687.13 PRP84539.1 - 0.63 10.4 2.9 26 5.2 0.2 2.4 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal RicinB_lectin_2 PF14200.6 PRP84540.1 - 1.1e-08 35.7 1.1 1.5e-07 32.1 0.4 2.6 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like AAA_28 PF13521.6 PRP84540.1 - 1.4e-08 35.1 0.0 2.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Ricin_B_lectin PF00652.22 PRP84540.1 - 0.00015 22.0 0.0 0.00034 20.8 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain AAA_18 PF13238.6 PRP84540.1 - 0.0005 20.6 0.0 0.0017 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain C1_2 PF03107.16 PRP84541.1 - 0.031 14.6 4.6 0.13 12.6 1.5 2.6 2 0 0 2 2 2 0 C1 domain PRAI PF00697.22 PRP84541.1 - 0.037 13.8 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Pribosyltran PF00156.27 PRP84542.1 - 1.5e-17 63.6 0.0 2.1e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PRP84542.1 - 0.027 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase ARID PF01388.21 PRP84544.1 - 3.1e-17 63.0 0.1 6.9e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain FYRN PF05964.14 PRP84544.1 - 1.2e-10 41.1 0.1 2.4e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 PRP84544.1 - 2.2e-05 24.5 0.0 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 F/Y rich C-terminus DP PF08781.10 PRP84544.1 - 0.035 14.0 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Transcription factor DP Peptidase_C53 PF05550.11 PRP84544.1 - 0.056 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 RRP36 PF06102.12 PRP84546.1 - 4.2e-22 78.9 25.8 4.2e-22 78.9 25.8 2.7 1 1 2 3 3 3 1 rRNA biogenesis protein RRP36 Ras PF00071.22 PRP84547.1 - 5.9e-34 117.0 0.4 4.3e-33 114.2 0.4 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP84547.1 - 1.7e-25 89.6 0.4 3.6e-24 85.3 0.4 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP84547.1 - 3.5e-09 36.4 0.0 4.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP84547.1 - 3.1e-06 26.9 0.0 3.1e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 PRP84547.1 - 0.03 14.1 0.0 0.045 13.5 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein ArgoMid PF16487.5 PRP84547.1 - 0.055 13.7 0.1 0.26 11.6 0.1 2.0 2 0 0 2 2 2 0 Mid domain of argonaute Gtr1_RagA PF04670.12 PRP84547.1 - 0.057 12.8 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AICARFT_IMPCHas PF01808.18 PRP84548.1 - 3.6e-77 259.7 0.0 6.6e-77 258.9 0.0 1.4 1 1 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 PRP84548.1 - 4.8e-25 87.6 0.1 9.2e-25 86.7 0.1 1.5 1 0 0 1 1 1 1 MGS-like domain CIMR PF00878.18 PRP84549.1 - 1.3e-05 25.3 3.8 0.45 10.6 0.1 3.2 3 0 0 3 3 3 3 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 PRP84549.1 - 0.00074 19.5 2.7 1.6 8.5 0.0 3.4 1 1 3 4 4 4 2 Autophagy-related protein 27 EF-hand_5 PF13202.6 PRP84550.1 - 0.00064 19.1 7.9 2.2 7.9 0.3 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PRP84550.1 - 0.011 15.6 3.9 28 5.0 0.1 3.6 3 0 0 3 3 3 0 EF-hand domain EF-hand_7 PF13499.6 PRP84550.1 - 0.1 13.0 3.7 48 4.5 0.0 3.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 PRP84550.1 - 0.55 10.1 4.1 17 5.4 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain pair Dockerin_1 PF00404.18 PRP84550.1 - 3.4 7.9 8.3 64 3.9 0.0 3.9 3 1 1 4 4 4 0 Dockerin type I domain Pkinase PF00069.25 PRP84551.1 - 4.3e-71 239.4 0.0 6.5e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84551.1 - 4.9e-40 137.4 0.0 7.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP84551.1 - 0.00016 21.7 0.1 0.00098 19.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP84551.1 - 0.00026 20.4 0.0 0.00045 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP84551.1 - 0.0022 17.0 0.1 0.0042 16.1 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 PRP84551.1 - 0.0038 16.8 1.1 0.0061 16.2 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 PRP84551.1 - 0.0085 15.5 0.1 0.019 14.3 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.22 PRP84552.1 - 2.1e-50 164.4 21.4 0.00021 21.3 0.0 13.7 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.6 PRP84552.1 - 6.5e-36 122.6 8.1 5.9e-09 36.2 0.1 7.2 3 2 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 PRP84552.1 - 4.9e-17 62.3 0.0 7.4e-05 23.3 0.0 6.5 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 PRP84552.1 - 3.3e-14 53.3 5.1 0.0011 19.1 0.0 5.8 4 2 2 6 6 6 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PRP84552.1 - 6.2e-12 45.8 8.4 0.061 13.8 0.0 8.9 9 2 1 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.20 PRP84552.1 - 3.8e-11 42.3 0.2 0.0016 17.1 0.0 4.7 3 2 2 5 5 5 3 Adaptin N terminal region RTP1_C1 PF10363.9 PRP84552.1 - 6.1e-08 32.8 0.8 0.36 11.0 0.0 5.3 5 1 1 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 PRP84552.1 - 5.5e-07 29.4 6.4 1.8 8.7 0.0 7.3 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 PRP84552.1 - 0.05 13.2 0.2 6.5 6.2 0.1 2.5 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DNA_alkylation PF08713.11 PRP84552.1 - 0.065 12.9 0.0 4.6 6.9 0.0 3.2 4 0 0 4 4 4 0 DNA alkylation repair enzyme IFRD PF05004.13 PRP84552.1 - 0.15 11.1 0.2 4.8 6.2 0.0 3.0 2 2 1 3 3 3 0 Interferon-related developmental regulator (IFRD) Ribosomal_L24e PF01246.20 PRP84553.1 - 1.3e-27 95.8 0.7 4.1e-27 94.2 0.7 1.9 1 0 0 1 1 1 1 Ribosomal protein L24e FmdE PF02663.14 PRP84553.1 - 1.3 9.1 5.4 0.34 10.9 1.5 1.9 1 1 1 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon CDPS PF16715.5 PRP84553.1 - 2.7 7.6 8.7 4.1 7.0 8.7 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase FGF-BP1 PF06473.12 PRP84553.1 - 10 5.9 10.4 17 5.1 10.4 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) ADH_zinc_N PF00107.26 PRP84555.1 - 2.5e-10 40.4 0.0 4.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP84555.1 - 0.00027 22.0 0.0 0.00049 21.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PRP84555.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF4534 PF15049.6 PRP84555.1 - 0.023 14.5 0.8 0.023 14.5 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4534) ADH_N PF08240.12 PRP84555.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Homeodomain PF00046.29 PRP84556.1 - 7e-12 45.0 10.2 1.9e-10 40.4 1.2 2.6 3 0 0 3 3 3 2 Homeodomain Sulfate_transp PF00916.20 PRP84558.1 - 1.9e-105 352.8 22.7 2.4e-105 352.4 22.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PRP84558.1 - 1.6e-11 43.9 0.0 4.4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 PRP84558.1 - 0.00019 21.8 17.9 0.0019 18.6 3.7 3.0 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 PRP84558.1 - 0.0057 17.0 0.0 0.025 14.9 0.0 2.1 1 1 0 1 1 1 1 STAS domain Tim17 PF02466.19 PRP84558.1 - 5.1 7.5 8.4 4 7.8 0.2 3.0 3 0 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Chitin_bind_1 PF00187.19 PRP84559.1 - 6.6e-08 32.9 20.0 1.9e-07 31.5 20.0 1.8 1 0 0 1 1 1 1 Chitin recognition protein GRP PF07172.11 PRP84559.1 - 0.18 12.5 16.1 0.31 11.8 16.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family AAA_12 PF13087.6 PRP84560.1 - 3.2e-40 137.9 0.0 7.2e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PRP84560.1 - 2.2e-25 89.9 0.0 2.2e-25 89.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PRP84560.1 - 2.9e-06 27.7 0.0 1.5e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PRP84560.1 - 4.5e-06 26.2 0.0 0.0099 15.2 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 PRP84560.1 - 1.3e-05 25.0 0.0 0.0041 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PRP84560.1 - 0.017 15.4 0.6 5 7.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 PRP84560.1 - 0.077 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UvrD-helicase PF00580.21 PRP84560.1 - 0.14 11.7 4.1 0.15 11.5 0.0 2.8 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain ING PF12998.7 PRP84560.1 - 0.27 11.8 7.6 13 6.5 0.1 4.3 4 0 0 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding Vac7 PF12751.7 PRP84560.1 - 4.5 6.6 5.1 8 5.8 5.1 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Abhydrolase_1 PF00561.20 PRP84561.1 - 7.9e-14 51.9 0.0 6.6e-10 39.1 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP84561.1 - 5.2e-09 37.0 0.0 6.6e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP84561.1 - 7.9e-09 35.1 0.1 2.8e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PRP84561.1 - 0.0059 16.1 0.1 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 PRP84561.1 - 0.017 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 PRP84561.1 - 0.026 14.1 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 PRP84561.1 - 0.048 13.5 0.0 6 6.7 0.0 2.8 2 1 1 3 3 3 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 PRP84561.1 - 0.12 11.8 0.0 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase ATP11 PF06644.11 PRP84562.1 - 8.3e-30 104.5 0.1 1.2e-29 104.0 0.1 1.2 1 1 0 1 1 1 1 ATP11 protein DUF296 PF03479.15 PRP84563.1 - 4.9e-24 84.8 0.1 5.8e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain FAD_binding_4 PF01565.23 PRP84564.1 - 3.1e-30 104.7 3.8 4.8e-30 104.1 3.8 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PRP84564.1 - 5.3e-09 36.0 0.4 1.3e-08 34.8 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like Rsm22 PF09243.10 PRP84565.1 - 1.8e-56 191.4 0.0 3e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 PRP84565.1 - 2.2e-08 34.1 0.0 4.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP84565.1 - 7.7e-06 26.6 0.0 1.6e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP84565.1 - 3.9e-05 24.3 0.0 0.00013 22.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP84565.1 - 0.00039 21.0 0.0 0.0013 19.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Pkinase_Tyr PF07714.17 PRP84566.1 - 1.4e-37 129.4 0.0 1.8e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84566.1 - 2.2e-21 76.4 0.0 3.2e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP84566.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PTCB-BRCT PF12738.7 PRP84567.1 - 7.1e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 PRP84567.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.4 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain COX14 PF14880.6 PRP84568.1 - 6.9 6.6 6.1 1.1 9.2 1.4 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DLH PF01738.18 PRP84569.1 - 1.5e-27 96.6 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 PRP84569.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP84569.1 - 0.09 12.0 0.1 1.3 8.2 0.0 2.3 2 1 1 3 3 3 0 Serine aminopeptidase, S33 PrgH PF09480.10 PRP84569.1 - 0.22 10.8 0.0 0.31 10.3 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Mob1_phocein PF03637.17 PRP84570.1 - 2.1e-48 164.6 2.9 2.5e-48 164.3 2.9 1.0 1 0 0 1 1 1 1 Mob1/phocein family SET PF00856.28 PRP84571.1 - 1e-11 45.5 0.0 4.1e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 SET domain TPR_19 PF14559.6 PRP84571.1 - 0.064 13.8 0.2 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_Bact PF18768.1 PRP84571.1 - 0.11 12.1 0.1 0.31 10.6 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix bacterial domain SAF PF08666.12 PRP84571.1 - 0.11 13.1 0.0 17 6.1 0.0 2.6 2 0 0 2 2 2 0 SAF domain Carb_bind PF10645.9 PRP84572.1 - 1.9e-05 24.8 31.9 0.00018 21.6 10.0 5.6 3 2 1 5 5 5 3 Carbohydrate binding LysM PF01476.20 PRP84573.1 - 8e-08 32.2 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 LysM domain BTK PF00779.19 PRP84573.1 - 2.5e-05 24.0 5.5 0.00012 21.8 5.5 2.0 1 1 0 1 1 1 1 BTK motif CHORD PF04968.12 PRP84573.1 - 0.48 11.2 5.2 1.5 9.6 4.9 2.0 1 1 0 1 1 1 0 CHORD Ham1p_like PF01725.16 PRP84574.1 - 4e-56 189.9 0.0 4.4e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family GTP_EFTU PF00009.27 PRP84575.1 - 7.5e-62 208.3 0.3 1.1e-61 207.8 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PRP84575.1 - 3.1e-37 127.1 0.0 7.6e-37 125.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 PRP84575.1 - 1.6e-29 101.8 0.0 3.5e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PRP84575.1 - 3.6e-28 97.4 1.6 9.4e-28 96.1 0.5 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PRP84575.1 - 4.4e-10 39.8 0.0 1.6e-09 38.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PRP84575.1 - 2.1e-05 24.4 0.0 4.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 PRP84575.1 - 0.00041 20.8 0.1 0.0074 16.7 0.1 2.4 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 PRP84575.1 - 0.0013 18.8 0.0 0.0042 17.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PRP84575.1 - 0.037 13.3 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SUI1 PF01253.22 PRP84575.1 - 0.038 14.5 0.1 1.7 9.2 0.0 3.4 3 0 0 3 3 3 0 Translation initiation factor SUI1 Citrate_synt PF00285.21 PRP84575.1 - 0.043 12.9 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain FeoB_N PF02421.18 PRP84575.1 - 0.054 13.0 0.1 0.32 10.5 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B 2OG-FeII_Oxy_3 PF13640.6 PRP84576.1 - 4.7e-12 46.6 0.0 1.4e-11 45.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PRP84576.1 - 0.002 18.6 0.0 0.0072 16.8 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 PRP84576.1 - 0.044 12.9 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Con-6 PF10346.9 PRP84577.1 - 4.4e-69 228.2 27.3 5.7e-15 55.0 0.5 5.9 5 0 0 5 5 5 5 Conidiation protein 6 KGG PF10685.9 PRP84577.1 - 3.9e-16 58.7 1.7 1.4e-06 28.4 0.1 3.1 2 0 0 2 2 2 2 Stress-induced bacterial acidophilic repeat motif Arm-DNA-bind_3 PF13356.6 PRP84577.1 - 3.7e-10 40.0 6.3 2.7 8.4 0.0 5.4 4 1 1 5 5 5 5 Arm DNA-binding domain Phage_lambda_P PF06992.11 PRP84577.1 - 2.1e-06 27.5 11.7 2.2 8.0 0.1 5.2 5 0 0 5 5 5 4 Replication protein P PhdYeFM_antitox PF02604.19 PRP84577.1 - 3.2e-06 26.8 11.3 2.1 8.2 0.1 5.2 5 0 0 5 5 5 4 Antitoxin Phd_YefM, type II toxin-antitoxin system MotY_N PF18393.1 PRP84577.1 - 0.0017 18.5 7.4 13 6.0 0.1 5.0 3 1 2 5 5 5 0 MotY N-terminal domain Kelch_2 PF07646.15 PRP84577.1 - 0.0056 16.6 0.0 19 5.4 0.0 3.7 4 0 0 4 4 3 0 Kelch motif Get5_C PF18514.1 PRP84577.1 - 0.0064 16.2 2.7 2 8.2 0.1 3.8 4 0 0 4 4 4 1 Get5 C-terminal domain YajC PF02699.15 PRP84577.1 - 0.026 14.4 14.5 3.1 7.8 0.1 5.0 5 0 0 5 5 5 0 Preprotein translocase subunit DUF3683 PF12447.8 PRP84577.1 - 0.14 12.3 6.6 10 6.3 0.1 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3683) SpoIIIAH PF12685.7 PRP84577.1 - 0.18 11.6 60.7 0.17 11.7 0.6 6.6 3 1 2 5 5 4 0 SpoIIIAH-like protein THDPS_N_2 PF14805.6 PRP84577.1 - 0.44 10.8 10.1 24 5.2 0.2 4.6 5 0 0 5 5 5 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal CCDC66 PF15236.6 PRP84577.1 - 0.94 9.3 25.5 3.1 7.6 1.6 4.5 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 66 TetR_C_19 PF17924.1 PRP84577.1 - 3 8.5 6.4 81 3.8 0.0 4.5 5 0 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain DUF2095 PF09868.9 PRP84577.1 - 3.8 7.5 9.6 18 5.3 0.7 3.5 3 1 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2095) G_glu_transpept PF01019.21 PRP84578.1 - 4.2e-115 385.4 0.0 5.3e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase UCR_6-4kD PF08997.10 PRP84579.1 - 5.4e-05 23.0 2.5 0.00016 21.5 2.4 1.9 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.9 PRP84579.1 - 8.4e-05 22.6 3.3 0.00028 20.9 3.3 1.8 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4311 PF14188.6 PRP84579.1 - 0.029 14.2 0.8 0.031 14.1 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) Thg1 PF04446.12 PRP84580.1 - 1.2e-31 109.4 0.1 2.1e-31 108.6 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Spt20 PF12090.8 PRP84580.1 - 2e-05 24.3 0.1 0.19 11.3 0.0 2.3 2 0 0 2 2 2 2 Spt20 family Bac_DNA_binding PF00216.21 PRP84580.1 - 0.014 15.6 1.2 6.3 7.1 0.1 2.7 1 1 1 2 2 2 0 Bacterial DNA-binding protein DUF4085 PF13315.6 PRP84580.1 - 0.032 13.9 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) PHD PF00628.29 PRP84581.1 - 4.3e-12 45.7 24.6 8.5e-09 35.2 6.4 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 PRP84581.1 - 0.00079 18.9 15.5 0.077 12.6 4.8 2.4 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 PRP84581.1 - 0.51 9.9 19.0 0.052 13.2 3.0 3.7 4 0 0 4 4 4 0 PHD/FYVE-zinc-finger like domain zf-CW PF07496.15 PRP84581.1 - 6.6 6.8 8.8 11 6.1 5.0 2.6 2 0 0 2 2 2 0 CW-type Zinc Finger Tubulin PF00091.25 PRP84582.1 - 9.3e-35 120.6 0.0 2.4e-25 89.9 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Baculo_PEP_C PF04513.12 PRP84584.1 - 0.11 12.6 1.2 0.22 11.6 0.3 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 PRP84584.1 - 0.16 12.0 0.8 0.34 10.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PH PF00169.29 PRP84586.1 - 2.5e-12 47.2 1.3 3.8e-08 33.8 0.1 3.3 3 0 0 3 3 3 2 PH domain PH_8 PF15409.6 PRP84586.1 - 0.00014 22.1 2.5 0.00089 19.5 1.8 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 PRP84586.1 - 3.8 8.0 5.5 25 5.4 2.3 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain Pet100 PF09803.9 PRP84587.1 - 0.0001 22.8 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 Pet100 RNA_polI_A34 PF08208.11 PRP84588.1 - 1.5e-19 70.9 50.8 1.5e-19 70.9 50.8 3.6 2 2 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF3905 PF13045.6 PRP84588.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) DUF4045 PF13254.6 PRP84588.1 - 0.058 13.0 48.6 0.012 15.3 17.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Herpes_BBRF1 PF04793.12 PRP84590.1 - 0.043 12.9 0.1 0.12 11.4 0.1 1.7 1 0 0 1 1 1 0 BRRF1-like protein RPN7 PF10602.9 PRP84591.1 - 1.4e-54 184.4 3.6 1.4e-54 184.4 3.6 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 PRP84591.1 - 1e-15 58.1 0.1 3.4e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 PCI domain CS PF04969.16 PRP84591.1 - 0.0024 18.9 5.0 0.0035 18.3 2.6 2.6 2 1 0 2 2 2 1 CS domain Glyco_hydro_71 PF03659.14 PRP84595.1 - 5.7e-85 285.4 23.6 9e-85 284.7 23.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.19 PRP84595.1 - 4.3e-11 42.8 14.3 1.3e-10 41.3 14.3 1.9 1 0 0 1 1 1 1 WSC domain Pur_ac_phosph_N PF16656.5 PRP84595.1 - 0.038 14.6 0.0 0.038 14.6 0.0 3.3 3 1 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Spt20 PF12090.8 PRP84596.1 - 8.5e-26 91.0 9.7 7.3e-24 84.7 0.0 2.5 2 0 0 2 2 2 1 Spt20 family Ank_2 PF12796.7 PRP84597.1 - 2.8e-25 88.7 0.8 6.4e-12 45.9 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84597.1 - 8.2e-23 80.5 0.5 7.6e-06 26.4 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP84597.1 - 7.3e-21 74.0 1.2 8.7e-10 38.7 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84597.1 - 1.3e-20 71.2 0.5 8e-06 25.8 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Bromodomain PF00439.25 PRP84597.1 - 8.1e-18 64.3 0.3 2.3e-17 62.8 0.3 1.8 1 0 0 1 1 1 1 Bromodomain Ank PF00023.30 PRP84597.1 - 9.4e-16 57.5 0.7 0.00012 22.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat BTB PF00651.31 PRP84597.1 - 2e-10 40.8 0.0 5.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF503 PF04456.12 PRP84597.1 - 0.073 12.9 2.6 7.7 6.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF503) MCR_alpha PF02249.17 PRP84598.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF547 PF04784.14 PRP84599.1 - 3.6e-15 56.1 0.0 1e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.21 PRP84599.1 - 4.5e-12 45.9 0.5 3.6e-11 43.0 0.0 2.7 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FtsJ PF01728.19 PRP84599.1 - 4e-06 27.0 0.0 1.7e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase NDT80_PhoG PF05224.12 PRP84599.1 - 0.11 12.7 2.1 0.65 10.2 0.3 2.3 2 0 0 2 2 2 0 NDT80 / PhoG like DNA-binding family AAR2 PF05282.11 PRP84601.1 - 3.3e-80 270.1 0.1 3.9e-80 269.9 0.1 1.0 1 0 0 1 1 1 1 AAR2 protein RhoGAP PF00620.27 PRP84603.1 - 8.7e-49 165.2 0.1 1.4e-48 164.6 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain EGF_2 PF07974.13 PRP84604.1 - 0.0081 16.5 6.1 0.014 15.8 6.1 1.3 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 PRP84604.1 - 0.044 14.4 7.2 0.082 13.6 7.2 1.5 1 0 0 1 1 1 0 Human growth factor-like EGF DUF1146 PF06612.11 PRP84604.1 - 0.26 11.4 6.9 0.24 11.5 0.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1146) DUF5313 PF17240.2 PRP84604.1 - 0.44 11.0 7.1 0.83 10.1 1.2 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5313) Pilin_N PF07790.11 PRP84604.1 - 1 10.4 4.2 6.3 7.8 0.5 2.6 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal ABC_tran PF00005.27 PRP84606.1 - 6.6e-31 107.6 0.0 1.2e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP84606.1 - 7.2e-17 61.5 24.4 9.7e-17 61.1 24.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP84606.1 - 2.9e-12 47.0 0.3 1.5e-08 34.8 0.0 2.5 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PRP84606.1 - 0.00011 21.7 0.0 0.00059 19.3 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 PRP84606.1 - 0.0021 17.8 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_15 PF13175.6 PRP84606.1 - 0.007 16.1 0.0 0.72 9.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 PRP84606.1 - 0.012 15.1 0.5 0.023 14.1 0.2 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF4162 PF13732.6 PRP84606.1 - 0.039 14.7 0.0 0.072 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_23 PF13476.6 PRP84606.1 - 0.083 13.4 0.3 0.17 12.3 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP84606.1 - 0.11 12.2 0.2 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SPG48 PF14764.6 PRP84608.1 - 4.1e-23 82.1 3.3 5e-23 81.8 0.8 2.5 3 0 0 3 3 3 1 AP-5 complex subunit, vesicle trafficking CorA PF01544.18 PRP84609.1 - 7.8 5.7 6.0 9.5 5.4 2.3 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein BTB PF00651.31 PRP84610.1 - 8.1e-13 48.6 0.2 1.2e-06 28.8 0.0 2.9 2 1 0 2 2 2 2 BTB/POZ domain F5_F8_type_C PF00754.25 PRP84610.1 - 0.00018 21.6 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain DUF3342 PF11822.8 PRP84610.1 - 0.11 12.7 0.0 0.38 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) GIDA_assoc PF13932.6 PRP84610.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 GidA associated domain COX16 PF14138.6 PRP84611.1 - 2.4e-21 76.0 0.1 2.8e-21 75.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 EZH2_WD-Binding PF11616.8 PRP84611.1 - 2.2 8.5 5.0 2.1 8.5 1.5 2.3 2 0 0 2 2 2 0 WD repeat binding protein EZH2 Methyltransf_12 PF08242.12 PRP84612.1 - 7.2e-19 68.4 0.0 1.7e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP84612.1 - 3.1e-16 59.9 0.0 6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP84612.1 - 1.1e-13 51.4 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP84612.1 - 6.3e-13 49.2 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP84612.1 - 2.4e-12 46.9 0.0 4.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PRP84612.1 - 8.3e-08 31.8 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 PRP84612.1 - 6e-07 29.2 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PRP84612.1 - 1.2e-06 28.1 0.0 2.3e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 PRP84612.1 - 2.2e-05 24.0 0.1 0.00038 20.0 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_16 PF10294.9 PRP84612.1 - 0.00025 20.9 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase CheR PF01739.18 PRP84612.1 - 0.00045 19.8 0.1 0.9 9.0 0.0 2.5 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_PK PF05891.12 PRP84612.1 - 0.00094 18.8 0.2 0.0022 17.6 0.0 1.6 2 0 0 2 2 2 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 PRP84612.1 - 0.0033 16.9 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Rsm22 PF09243.10 PRP84612.1 - 0.051 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 adh_short PF00106.25 PRP84613.1 - 3.1e-42 144.2 0.4 5e-42 143.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP84613.1 - 9.1e-34 117.0 0.0 2.3e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP84613.1 - 3.9e-07 30.2 0.6 8.1e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 PRP84613.1 - 0.00025 21.0 1.1 0.00038 20.4 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 PRP84613.1 - 0.0009 19.9 0.0 0.0063 17.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain V-ATPase_H_N PF03224.14 PRP84613.1 - 0.043 13.1 0.8 1.1 8.5 0.2 2.6 2 1 0 2 2 2 0 V-ATPase subunit H Pyr_redox_2 PF07992.14 PRP84613.1 - 0.05 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 PRP84613.1 - 0.067 12.5 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 PRP84613.1 - 0.087 12.4 0.1 0.33 10.5 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 PRP84613.1 - 0.16 12.6 0.3 0.62 10.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TEX33 PF15400.6 PRP84613.1 - 0.16 12.4 0.9 2.3 8.7 0.0 3.0 3 0 0 3 3 3 0 Testis-expressed sequence 33 protein family Ecl1 PF12855.7 PRP84613.1 - 5.3 8.2 13.2 13 6.9 13.2 1.6 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Arm PF00514.23 PRP84613.1 - 7.1 6.8 10.2 1.9 8.6 0.1 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Fapy_DNA_glyco PF01149.24 PRP84614.1 - 4.1e-12 46.8 0.2 2e-11 44.5 0.2 2.1 1 1 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Neil1-DNA_bind PF09292.10 PRP84614.1 - 3.4e-07 30.1 0.5 9.2e-07 28.7 0.5 1.7 1 0 0 1 1 1 1 Endonuclease VIII-like 1, DNA bind H2TH PF06831.14 PRP84614.1 - 5.9e-07 29.4 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Pkinase PF00069.25 PRP84615.1 - 1.4e-29 103.3 0.3 3.4e-29 102.0 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84615.1 - 9.5e-16 57.9 0.1 1.6e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PRP84615.1 - 0.11 12.1 0.4 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kin17_mid PF10357.9 PRP84616.1 - 1.1e-43 148.1 0.7 1.1e-43 148.1 0.7 2.2 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 PRP84616.1 - 1.4e-21 76.3 8.1 3.4e-21 75.1 8.1 1.7 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain DUF2470 PF10615.9 PRP84616.1 - 0.019 15.6 0.2 0.05 14.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) NdhS PF11623.8 PRP84616.1 - 0.03 14.0 0.4 1.5 8.5 0.2 2.4 2 0 0 2 2 2 0 NAD(P)H dehydrogenase subunit S zf-C2H2_jaz PF12171.8 PRP84616.1 - 0.033 14.5 5.0 0.068 13.5 5.0 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PRP84616.1 - 0.054 13.8 0.9 0.054 13.8 0.9 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PRP84616.1 - 0.12 12.8 5.9 0.25 11.8 5.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF629 PF04780.12 PRP84616.1 - 0.23 10.0 8.5 0.43 9.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Ank_4 PF13637.6 PRP84617.1 - 7.8e-12 45.5 1.8 0.0024 18.4 0.0 6.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) RRM_1 PF00076.22 PRP84617.1 - 1.5e-07 31.1 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 PRP84617.1 - 7.9e-07 29.6 0.0 0.0086 16.7 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP84617.1 - 1.6e-05 24.9 0.3 18 6.3 0.0 6.3 5 1 2 7 7 7 1 Ankyrin repeat Ank_5 PF13857.6 PRP84617.1 - 0.00062 20.0 1.0 0.098 13.0 0.0 4.7 5 2 1 7 7 7 1 Ankyrin repeats (many copies) SH3_9 PF14604.6 PRP84618.1 - 1.7e-14 53.4 0.3 3.7e-14 52.3 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP84618.1 - 2.6e-13 49.3 0.1 4.7e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 PRP84618.1 - 7.5e-13 48.6 0.1 7.5e-13 48.6 0.1 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 PRP84618.1 - 2.9e-09 36.4 0.0 7.1e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 PRP84618.1 - 0.0024 17.9 2.1 0.0032 17.6 0.1 2.2 2 0 0 2 2 2 1 Hr1 repeat Uds1 PF15456.6 PRP84618.1 - 0.38 10.9 0.0 0.38 10.9 0.0 2.8 2 1 0 2 2 2 0 Up-regulated During Septation Vps5 PF09325.10 PRP84618.1 - 0.5 9.9 23.2 0.05 13.1 11.2 3.6 2 2 2 4 4 4 0 Vps5 C terminal like DUF496 PF04363.12 PRP84618.1 - 0.56 10.3 5.3 2.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF496) HOCHOB PF17943.1 PRP84618.1 - 2.3 9.0 6.1 0.42 11.3 1.0 2.2 2 1 0 2 2 2 0 Homeobox-cysteine loop-homeobox Fzo_mitofusin PF04799.13 PRP84618.1 - 2.4 7.7 8.7 0.14 11.7 3.2 1.7 2 0 0 2 2 2 0 fzo-like conserved region DUF4394 PF14339.6 PRP84619.1 - 8.7e-19 67.8 2.5 8.7e-19 67.8 2.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4394) SARAF PF06682.12 PRP84620.1 - 0.073 12.7 0.0 0.078 12.6 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Endomucin PF07010.12 PRP84620.1 - 0.14 12.1 2.8 0.1 12.6 1.7 1.4 1 1 0 1 1 1 0 Endomucin BRO1 PF03097.18 PRP84621.1 - 3.9e-33 114.8 0.0 5e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain TPR_MalT PF17874.1 PRP84621.1 - 0.0027 17.1 0.4 0.0051 16.2 0.4 1.4 1 0 0 1 1 1 1 MalT-like TPR region Sec20 PF03908.13 PRP84621.1 - 0.14 12.1 3.0 0.18 11.8 1.5 1.9 2 0 0 2 2 2 0 Sec20 2-Hacid_dh_C PF02826.19 PRP84622.1 - 2.1e-50 170.5 0.1 3.6e-50 169.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PRP84622.1 - 3.1e-35 120.8 0.1 4.3e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PRP84622.1 - 3.3e-07 30.6 0.5 1.9e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 PRP84622.1 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 PRP84622.1 - 0.0044 17.5 0.0 0.02 15.4 0.0 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.12 PRP84622.1 - 0.039 13.5 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glyco_trans_4_2 PF13477.6 PRP84622.1 - 0.053 13.6 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like UDPG_MGDP_dh_N PF03721.14 PRP84622.1 - 0.062 12.9 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Beach PF02138.18 PRP84623.1 - 2.6e-121 404.2 0.0 4.7e-121 403.4 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 PRP84623.1 - 8.4e-29 100.7 2.1 2.7e-28 99.0 2.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 PRP84623.1 - 7.1e-22 77.4 0.0 1.7e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 PRP84623.1 - 8.2e-13 48.2 1.5 2e-12 46.9 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 PRP84623.1 - 1.3e-09 38.5 8.6 0.00047 20.9 0.2 4.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 PRP84623.1 - 4.8e-07 30.0 0.0 9.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily ANAPC4_WD40 PF12894.7 PRP84623.1 - 3e-05 24.2 0.2 0.05 13.9 0.0 3.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1088 PF06469.11 PRP84623.1 - 3.7e-05 23.5 0.2 8.4e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) V-ATPase_H_N PF03224.14 PRP84623.1 - 0.16 11.2 3.4 0.19 11.0 0.0 2.9 3 1 0 3 3 3 0 V-ATPase subunit H MRP_L53 PF10780.9 PRP84623.1 - 0.23 11.7 0.5 2.3 8.5 0.1 2.8 2 0 0 2 2 2 0 39S ribosomal protein L53/MRP-L53 HATPase_c PF02518.26 PRP84625.1 - 1.1e-27 96.8 0.0 3.1e-27 95.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP84625.1 - 2.5e-21 75.9 1.5 1.3e-19 70.4 0.2 3.2 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 PRP84625.1 - 0.0025 17.8 1.5 0.047 13.7 0.1 3.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Csm2_III-A PF03750.13 PRP84625.1 - 0.033 15.0 0.5 0.13 13.1 0.5 2.0 1 0 0 1 1 1 0 Csm2 Type III-A PAN_4 PF14295.6 PRP84626.1 - 1.1e-09 38.0 5.3 1.1e-09 38.0 5.3 2.7 2 0 0 2 2 2 1 PAN domain Chitin_bind_1 PF00187.19 PRP84626.1 - 2.4e-06 27.9 21.9 2.4e-06 27.9 21.9 2.9 3 0 0 3 3 3 1 Chitin recognition protein DUF5329 PF17263.2 PRP84626.1 - 0.028 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5329) PAN_4 PF14295.6 PRP84627.1 - 2.8e-10 39.9 6.1 2.8e-10 39.9 6.1 2.7 2 0 0 2 2 2 1 PAN domain Chitin_bind_1 PF00187.19 PRP84627.1 - 7.5e-07 29.5 22.7 7.5e-07 29.5 22.7 3.3 3 0 0 3 3 3 1 Chitin recognition protein PAN_1 PF00024.26 PRP84627.1 - 9.6e-05 22.3 0.5 0.00025 21.0 0.5 1.6 1 0 0 1 1 1 1 PAN domain DUF5329 PF17263.2 PRP84627.1 - 0.00061 19.9 0.0 0.082 13.1 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5329) PAN_4 PF14295.6 PRP84628.1 - 2.7e-10 40.0 4.9 2.7e-10 40.0 4.9 3.0 3 0 0 3 3 3 1 PAN domain Chitin_bind_1 PF00187.19 PRP84628.1 - 2.1e-05 24.9 23.8 2.1e-05 24.9 23.8 2.6 2 0 0 2 2 2 1 Chitin recognition protein Glyco_hydro_20 PF00728.22 PRP84629.1 - 2.1e-98 330.0 0.0 2.7e-98 329.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 PRP84629.1 - 3.3e-21 76.4 0.0 6e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 PRP84629.1 - 4.2e-05 24.3 0.0 8.7e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 adh_short PF00106.25 PRP84630.1 - 2.5e-40 138.0 0.8 3.5e-40 137.5 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP84630.1 - 1.4e-26 93.5 0.3 1.8e-26 93.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP84630.1 - 4.3e-08 33.3 0.2 7.3e-08 32.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Pax7 PF12360.8 PRP84630.1 - 0.049 13.8 0.7 0.1 12.8 0.7 1.5 1 0 0 1 1 1 0 Paired box protein 7 7TM_GPCR_Str PF10326.9 PRP84631.1 - 0.014 14.8 0.2 0.014 14.8 0.2 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str DUF4291 PF14124.6 PRP84631.1 - 0.056 13.3 0.1 0.061 13.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4291) Pkinase_Tyr PF07714.17 PRP84632.1 - 1.5e-16 60.5 0.1 8.2e-15 54.8 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP84632.1 - 2.6e-10 40.7 3.1 6.3e-10 39.4 3.1 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP84632.1 - 2.4e-09 36.9 0.0 1.6e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP84632.1 - 3.7e-06 27.2 0.6 1.2e-05 25.5 0.6 1.9 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP84632.1 - 3.8e-05 23.4 3.2 0.00027 20.6 2.5 2.4 1 1 1 2 2 2 2 Leucine rich repeat Insulin_TMD PF17870.1 PRP84632.1 - 0.093 12.8 3.9 0.22 11.6 3.9 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRR_1 PF00560.33 PRP84632.1 - 1.2 10.0 6.2 3.2 8.7 0.7 3.6 2 1 0 2 2 2 0 Leucine Rich Repeat Ank_2 PF12796.7 PRP84634.1 - 3.9e-16 59.4 5.0 2.6e-05 24.7 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84634.1 - 7.4e-09 36.0 8.6 0.0064 17.0 0.0 6.1 3 3 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84634.1 - 8.1e-09 35.0 1.3 1.9 9.3 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 PRP84634.1 - 0.0033 17.7 0.1 1.6 9.2 0.0 3.9 2 2 2 4 4 4 1 Ankyrin repeats (many copies) F-box PF00646.33 PRP84634.1 - 0.0037 17.1 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 F-box domain Ank PF00023.30 PRP84634.1 - 0.053 14.0 3.8 1.3 9.6 0.2 3.9 4 0 0 4 4 4 0 Ankyrin repeat F-box-like PF12937.7 PRP84634.1 - 0.086 12.7 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 F-box-like DUF3368 PF11848.8 PRP84634.1 - 0.14 11.9 1.7 0.49 10.2 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) SNF2_N PF00176.23 PRP84635.1 - 9.9e-38 129.7 0.1 2e-37 128.7 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 PRP84635.1 - 7.7e-10 39.0 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP84635.1 - 1e-09 38.7 0.1 2.4e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PRP84635.1 - 0.13 12.5 0.0 0.96 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DDHD PF02862.17 PRP84635.1 - 0.14 12.3 6.5 0.11 12.6 1.1 2.5 2 0 0 2 2 2 0 DDHD domain Uds1 PF15456.6 PRP84635.1 - 9.9 6.3 8.7 1.3 9.1 0.7 3.0 3 0 0 3 3 3 0 Up-regulated During Septation PAS PF00989.25 PRP84637.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 PRP84638.1 - 1.6e-17 63.8 0.0 5.1e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84638.1 - 6.4e-06 25.6 0.0 1.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.20 PRP84639.1 - 1.3e-19 68.8 29.7 5.6e-06 25.9 3.3 5.5 5 0 0 5 5 5 4 MORN repeat SNAPc_SNAP43 PF09808.9 PRP84639.1 - 4.2e-19 69.2 3.1 6e-19 68.7 0.1 2.3 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 F-box-like PF12937.7 PRP84639.1 - 5.5e-10 39.0 0.1 1.2e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP84639.1 - 1e-06 28.4 0.3 1e-06 28.4 0.3 1.8 2 0 0 2 2 2 1 F-box domain CPSF100_C PF13299.6 PRP84639.1 - 0.075 13.2 6.0 0.18 12.0 6.0 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 PRP84639.1 - 2.5 6.8 4.6 4 6.1 4.6 1.3 1 0 0 1 1 1 0 Presenilin SelR PF01641.18 PRP84640.1 - 5.2e-48 162.1 0.3 6.1e-48 161.9 0.3 1.0 1 0 0 1 1 1 1 SelR domain GFA PF04828.14 PRP84640.1 - 0.0023 18.2 0.9 0.029 14.7 0.1 2.2 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_10 PF10058.9 PRP84640.1 - 0.032 14.0 0.2 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 PRP84640.1 - 0.084 13.1 0.3 0.32 11.2 0.3 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_SprT PF17283.2 PRP84640.1 - 0.11 12.4 0.9 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-Mss51 PF13824.6 PRP84640.1 - 0.22 11.7 4.4 2 8.6 0.7 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Rap_GAP PF02145.15 PRP84641.1 - 2.8e-57 193.3 0.0 6.2e-57 192.2 0.0 1.6 1 0 0 1 1 1 1 Rap/ran-GAP AhpC-TSA_2 PF13911.6 PRP84641.1 - 1.8e-09 37.7 0.0 4.6e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 PRP84641.1 - 1.9e-06 27.8 0.0 5.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family EGF_2 PF07974.13 PRP84642.1 - 0.00076 19.8 7.4 0.0015 18.9 7.4 1.5 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 PRP84642.1 - 0.062 13.6 9.0 0.1 12.9 9.0 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 PRP84643.1 - 6.4e-05 23.2 42.7 0.016 15.5 9.7 3.8 3 0 0 3 3 3 2 EGF-like domain LAB_N PF07578.11 PRP84643.1 - 0.0038 17.3 10.3 6 7.0 0.2 4.1 3 0 0 3 3 3 3 Lipid A Biosynthesis N-terminal domain Metallothio_5 PF02067.15 PRP84643.1 - 0.018 15.2 22.7 0.78 9.9 3.3 3.6 3 0 0 3 3 3 0 Metallothionein family 5 DUF2556 PF10831.8 PRP84643.1 - 0.018 15.0 4.6 29 4.7 0.2 4.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2556) Longin PF13774.6 PRP84643.1 - 0.24 11.4 0.8 23 5.1 0.1 3.0 3 0 0 3 3 3 0 Regulated-SNARE-like domain GMC_oxred_N PF00732.19 PRP84644.1 - 1.5e-29 103.3 0.0 3.5e-29 102.1 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP84644.1 - 3e-16 60.2 0.0 5.9e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 PRP84644.1 - 0.057 12.7 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF455 PF04305.14 PRP84645.1 - 3.5e-76 256.0 2.9 4.2e-76 255.8 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF455) PH PF00169.29 PRP84646.1 - 4.2e-05 24.0 0.1 0.00021 21.8 0.0 2.3 2 0 0 2 2 2 1 PH domain F-box-like PF12937.7 PRP84646.1 - 0.054 13.4 0.4 0.14 12.1 0.4 1.7 1 0 0 1 1 1 0 F-box-like PRD PF00874.20 PRP84647.1 - 0.025 14.9 0.0 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 PRD domain PARP PF00644.20 PRP84649.1 - 5.7e-63 212.0 0.0 1.8e-62 210.4 0.0 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PRP84649.1 - 8.1e-40 136.1 0.7 6.5e-39 133.1 0.9 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 PRP84649.1 - 2.2e-18 66.1 4.9 3.8e-18 65.3 4.0 1.9 2 0 0 2 2 1 1 WGR domain PADR1 PF08063.12 PRP84649.1 - 2.4e-12 46.4 1.1 7.2e-12 44.9 1.1 1.8 1 0 0 1 1 1 1 PADR1 (NUC008) domain BRCT PF00533.26 PRP84649.1 - 5.2e-11 42.8 0.0 2.1e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PRP84649.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 PRP84649.1 - 0.00018 21.9 0.1 0.00085 19.7 0.1 2.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain TF_Zn_Ribbon PF08271.12 PRP84649.1 - 0.027 14.0 0.8 0.085 12.4 0.8 1.9 1 0 0 1 1 1 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 PRP84649.1 - 0.067 13.2 0.2 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ZirS_C PF16583.5 PRP84649.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Prim_Zn_Ribbon PF08273.12 PRP84649.1 - 0.13 12.5 3.5 1.9 8.8 1.4 2.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF108 PF01958.18 PRP84651.1 - 3.5e-20 72.1 0.1 8.5e-20 70.9 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF108 NAD_binding_3 PF03447.16 PRP84651.1 - 1.2e-11 45.3 0.0 2.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 PRP84651.1 - 6e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 PRP84651.1 - 8.6e-05 23.1 0.0 0.0003 21.3 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 PRP84651.1 - 0.0043 17.9 0.0 0.017 15.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 PRP84651.1 - 0.019 15.4 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PRP84651.1 - 0.029 14.5 0.0 0.063 13.4 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 PRP84651.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.6 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Gp_dh_N PF00044.24 PRP84651.1 - 0.17 12.2 0.0 0.72 10.2 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain His_Phos_1 PF00300.22 PRP84654.1 - 1.3e-15 57.6 0.0 3.9e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Methyltransf_16 PF10294.9 PRP84655.1 - 1.4e-26 93.3 0.2 2e-26 92.8 0.2 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 PRP84655.1 - 6.2e-08 32.6 0.0 8.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP84655.1 - 2.3e-06 27.5 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP84655.1 - 6.4e-05 22.6 0.0 0.00013 21.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP84655.1 - 0.00013 22.6 0.0 0.00027 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP84655.1 - 0.00018 21.0 0.0 0.00024 20.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 PRP84655.1 - 0.0028 18.4 0.0 0.0065 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PRP84655.1 - 0.0048 16.6 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 PRP84655.1 - 0.021 15.4 0.0 0.043 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 PRP84655.1 - 0.028 13.8 0.1 0.32 10.4 0.1 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TehB tRNA_U5-meth_tr PF05958.11 PRP84655.1 - 0.043 12.8 0.0 0.094 11.7 0.0 1.5 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase C2 PF00168.30 PRP84656.1 - 1.6e-09 38.0 0.1 3.1e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 C2 domain DUF3846 PF12957.7 PRP84657.1 - 0.089 13.1 0.2 0.25 11.7 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3846) G_glu_transpept PF01019.21 PRP84658.1 - 1.1e-151 506.1 0.0 1.4e-151 505.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DAGK_acc PF00609.19 PRP84659.1 - 1.8e-51 174.7 0.0 3.1e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PRP84659.1 - 2.6e-24 85.2 0.3 6.2e-24 84.0 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 PRP84659.1 - 1.7e-18 66.3 22.7 2.9e-12 46.3 9.9 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 PRP84659.1 - 0.00013 22.2 14.4 0.041 14.2 1.9 2.4 2 0 0 2 2 2 2 C1 domain zf-RING_9 PF13901.6 PRP84659.1 - 0.0018 18.3 17.7 0.023 14.7 2.7 2.5 3 0 0 3 3 2 2 Putative zinc-RING and/or ribbon Cnn_1N PF07989.11 PRP84659.1 - 0.005 17.0 1.7 0.013 15.6 1.7 1.7 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 ZapB PF06005.12 PRP84659.1 - 0.0058 17.0 0.7 0.014 15.8 0.7 1.6 1 0 0 1 1 1 1 Cell division protein ZapB DUF4618 PF15397.6 PRP84659.1 - 0.011 15.2 0.2 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CAGE1 PF15066.6 PRP84659.1 - 0.02 13.6 0.8 0.032 12.9 0.8 1.2 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family Csm1_N PF18504.1 PRP84659.1 - 0.025 14.9 5.1 0.056 13.8 5.1 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain zf-H2C2_2 PF13465.6 PRP84659.1 - 0.026 15.0 2.2 1 9.9 0.0 3.1 2 1 0 2 2 2 0 Zinc-finger double domain HAUS5 PF14817.6 PRP84659.1 - 0.041 12.7 0.4 0.063 12.0 0.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 FlaC_arch PF05377.11 PRP84659.1 - 0.096 13.1 0.8 0.26 11.7 0.8 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MctB PF11382.8 PRP84659.1 - 0.16 11.7 0.6 0.26 11.0 0.6 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Rootletin PF15035.6 PRP84659.1 - 0.17 11.9 2.8 0.31 11.0 2.8 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 PRP84659.1 - 0.38 10.5 4.5 0.88 9.4 4.5 1.6 1 0 0 1 1 1 0 Septum formation initiator FYVE_2 PF02318.16 PRP84659.1 - 1.3 9.3 12.5 1.1 9.5 0.9 3.1 3 0 0 3 3 3 0 FYVE-type zinc finger HALZ PF02183.18 PRP84659.1 - 5.4 7.3 8.4 5.1 7.4 0.6 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper Zf_RING PF16744.5 PRP84659.1 - 6 7.1 12.7 8.8 6.5 1.9 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger SEP PF08059.13 PRP84662.1 - 3.6e-20 72.3 0.1 8.4e-20 71.1 0.1 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 PRP84662.1 - 3.5e-13 49.6 0.0 7.8e-13 48.4 0.0 1.6 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 PRP84662.1 - 6.7e-09 35.4 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 PRP84662.1 - 1.6e-06 27.6 0.1 3.1e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain Med20 PF08612.11 PRP84663.1 - 1.3e-18 67.2 0.0 1.8e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Ras PF00071.22 PRP84664.1 - 8.3e-58 194.6 0.2 9.4e-58 194.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP84664.1 - 1.5e-22 80.1 0.0 2.5e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP84664.1 - 9.6e-13 48.0 0.0 1.2e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP84664.1 - 3.7e-06 26.6 0.1 6.9e-06 25.7 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP84664.1 - 7.8e-06 25.9 0.1 0.0093 15.9 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 PRP84664.1 - 0.00045 20.2 0.0 0.00092 19.2 0.0 1.5 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 PRP84664.1 - 0.00082 18.9 0.5 0.017 14.6 0.5 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 PRP84664.1 - 0.0064 16.6 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 PRP84664.1 - 0.054 13.3 0.1 0.11 12.3 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 PRP84664.1 - 0.095 12.0 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SPT16 PF08644.11 PRP84665.1 - 4.9 7.3 8.9 1.7 8.8 6.3 1.6 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) ABC_tran PF00005.27 PRP84668.1 - 9.2e-21 74.8 0.0 1.7e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane_2 PF06472.15 PRP84668.1 - 1.6e-20 73.7 1.6 2.2e-20 73.2 1.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 PRP84668.1 - 1.6e-05 24.5 0.6 0.0011 18.5 0.8 2.8 2 1 0 2 2 2 1 SbmA/BacA-like family RsgA_GTPase PF03193.16 PRP84668.1 - 0.0004 20.3 0.1 0.0008 19.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PRP84668.1 - 0.0015 18.0 0.3 0.076 12.4 0.3 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 PRP84668.1 - 0.0029 17.6 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PRRSV_2b PF07069.11 PRP84668.1 - 0.027 14.9 3.3 0.065 13.7 3.3 1.6 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b AAA_30 PF13604.6 PRP84668.1 - 0.028 14.2 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PRP84668.1 - 0.032 14.3 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SLATT_5 PF18160.1 PRP84668.1 - 0.038 13.3 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 AAA_16 PF13191.6 PRP84668.1 - 0.041 14.3 0.2 0.084 13.2 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PRP84668.1 - 0.044 14.1 0.7 0.42 10.9 0.6 2.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP84668.1 - 0.049 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 PRP84668.1 - 0.12 12.8 0.1 5.6 7.4 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 PRP84668.1 - 0.14 11.2 0.0 0.38 9.8 0.0 1.7 1 0 0 1 1 1 0 MCM P-loop domain RhoGEF PF00621.20 PRP84669.1 - 1.4e-45 155.8 0.2 8.9e-45 153.2 0.1 2.5 2 0 0 2 2 2 1 RhoGEF domain cNMP_binding PF00027.29 PRP84669.1 - 3.1e-22 78.4 0.6 3e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GRAM PF02893.20 PRP84669.1 - 1.1e-12 47.8 0.1 3.4e-12 46.2 0.1 1.9 1 0 0 1 1 1 1 GRAM domain COPI_C PF06957.11 PRP84669.1 - 7.8e-11 41.4 0.2 7.8e-11 41.4 0.2 3.1 2 1 1 3 3 2 1 Coatomer (COPI) alpha subunit C-terminus PH PF00169.29 PRP84669.1 - 1.2e-07 32.2 1.4 6.1e-07 29.9 0.2 2.6 2 0 0 2 2 2 1 PH domain EF-hand_6 PF13405.6 PRP84669.1 - 0.0004 20.1 0.5 0.7 10.0 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PRP84669.1 - 0.0021 18.0 0.0 0.009 15.9 0.0 2.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PRP84669.1 - 0.0026 17.2 0.1 0.14 11.7 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 PRP84669.1 - 0.03 13.8 0.2 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 EF hand DZR PF12773.7 PRP84669.1 - 0.19 11.8 2.8 0.42 10.7 2.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 PRP84669.1 - 1.3 8.6 5.0 2.4 7.7 5.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Bac_rhamnosid_C PF17390.2 PRP84670.1 - 1.9e-11 43.6 0.9 7.3e-11 41.7 0.4 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Inhibitor_I36 PF03995.13 PRP84670.1 - 0.019 14.9 0.5 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor family I36 DUF1080 PF06439.11 PRP84670.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) EPL1 PF10513.9 PRP84671.1 - 3.4e-09 37.3 2.3 6.4e-09 36.4 0.0 2.2 2 1 0 2 2 2 1 Enhancer of polycomb-like DnaJ PF00226.31 PRP84672.1 - 3.4e-23 81.5 1.6 7.7e-23 80.4 1.6 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 PRP84672.1 - 1.8e-19 69.9 4.0 4.3e-19 68.7 4.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DUF5638 PF18688.1 PRP84672.1 - 0.0059 16.9 0.2 0.02 15.2 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5638) MIT PF04212.18 PRP84672.1 - 0.016 15.3 0.6 0.016 15.3 0.6 2.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 PRP84672.1 - 0.019 15.0 0.4 0.019 15.0 0.4 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP84672.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP84672.1 - 0.42 11.3 3.3 4.9 7.9 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP84672.1 - 0.43 10.5 4.6 0.22 11.4 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat zf_UBZ PF18439.1 PRP84673.1 - 2.6e-06 26.9 26.8 0.47 10.1 0.1 6.3 6 0 0 6 6 6 5 Ubiquitin-Binding Zinc Finger zf_C2H2_13 PF18508.1 PRP84673.1 - 0.086 12.4 5.3 1.1 8.9 0.1 3.0 3 0 0 3 3 3 0 Zinc finger domain zf-WRNIP1_ubi PF18279.1 PRP84673.1 - 0.35 11.6 13.3 0.5 11.1 0.1 4.1 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-ACC PF17848.1 PRP84673.1 - 1 9.5 0.0 1 9.5 0.0 5.0 6 1 0 6 6 6 0 Acetyl-coA carboxylase zinc finger domain PRP21_like_P PF12230.8 PRP84673.1 - 10 5.9 15.9 0.34 10.7 0.2 3.9 3 2 1 4 4 4 0 Pre-mRNA splicing factor PRP21 like protein Sel1 PF08238.12 PRP84674.1 - 7.8e-29 99.5 15.6 0.00048 20.7 0.1 9.9 9 0 0 9 9 9 7 Sel1 repeat TPR_17 PF13431.6 PRP84674.1 - 0.00014 22.0 2.3 0.021 15.2 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP84674.1 - 0.0095 15.6 1.4 0.0095 15.6 1.4 3.5 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 PRP84674.1 - 1.3 8.9 7.5 0.49 10.3 1.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SPX PF03105.19 PRP84675.1 - 3.9e-33 115.9 8.0 2.1e-18 67.5 5.3 3.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 PRP84675.1 - 2.2e-28 99.6 36.1 4.6e-28 98.5 36.1 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PRP84675.1 - 3.2e-25 88.9 50.2 2.7e-22 79.3 26.2 2.7 1 1 2 3 3 3 2 Citrate transporter DUF4806 PF16064.5 PRP84675.1 - 0.1 12.9 0.0 7.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) Pex14_N PF04695.13 PRP84677.1 - 5.1e-21 76.0 0.2 5.1e-21 76.0 0.2 4.8 3 2 2 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region UPF0242 PF06785.11 PRP84677.1 - 0.011 15.9 11.2 0.079 13.1 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HeLo PF14479.6 PRP84677.1 - 0.031 14.1 0.4 0.031 14.1 0.4 2.2 2 0 0 2 2 2 0 Prion-inhibition and propagation UPF0184 PF03670.13 PRP84677.1 - 0.08 13.3 0.3 0.08 13.3 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) DFP PF04127.15 PRP84677.1 - 0.093 12.5 4.4 0.19 11.5 4.4 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CENP-O PF09496.10 PRP84677.1 - 2 8.3 8.1 0.14 12.1 1.7 2.0 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component Caldesmon PF02029.15 PRP84677.1 - 9.2 4.9 32.1 4.1 6.0 10.2 2.2 2 1 0 2 2 2 0 Caldesmon Virul_Fac PF10139.9 PRP84677.1 - 9.6 4.3 15.8 0.013 13.7 2.8 2.0 2 0 0 2 2 2 0 Putative bacterial virulence factor DUF773 PF05600.12 PRP84678.1 - 4e-113 378.8 13.1 5e-113 378.5 13.1 1.1 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 DUF1694 PF07997.11 PRP84678.1 - 0.094 12.8 1.6 2.4 8.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1694) IL2 PF00715.17 PRP84678.1 - 0.11 12.4 4.0 0.082 12.8 1.8 1.9 2 0 0 2 2 2 0 Interleukin 2 DASH_Duo1 PF08651.10 PRP84678.1 - 0.15 11.9 3.2 0.29 10.9 0.1 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 Laminin_II PF06009.12 PRP84678.1 - 0.98 9.4 6.9 0.67 10.0 0.1 2.9 2 1 0 2 2 2 0 Laminin Domain II KxDL PF10241.9 PRP84678.1 - 2.4 8.5 6.9 3.5 8.0 1.0 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF3450 PF11932.8 PRP84678.1 - 3 7.1 8.9 1.5 8.0 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PQ-loop PF04193.14 PRP84679.1 - 1e-14 54.0 11.5 1.4e-07 31.2 1.7 2.8 2 0 0 2 2 2 2 PQ loop repeat AAA_16 PF13191.6 PRP84679.1 - 0.00069 20.0 0.1 0.0028 18.0 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 PRP84679.1 - 0.0059 16.9 0.0 2 8.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 PRP84679.1 - 0.03 14.6 0.1 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PRP84679.1 - 0.096 11.9 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 PRP84679.1 - 0.21 11.5 0.0 0.6 10.0 0.0 1.8 2 0 0 2 2 2 0 NTPase SHIPPO-rpt PF07004.12 PRP84680.1 - 1e-119 386.4 261.5 1.2e-05 25.9 0.8 42.9 42 0 0 42 42 42 42 Sperm-tail PG-rich repeat ECR1_N PF14382.6 PRP84680.1 - 6.6e-20 70.6 109.6 29 4.6 0.0 37.1 39 2 0 39 39 39 20 Exosome complex exonuclease RRP4 N-terminal region SHIPPO-rpt PF07004.12 PRP84681.1 - 4.4e-50 166.4 91.3 0.00025 21.8 2.0 14.9 15 0 0 15 15 15 14 Sperm-tail PG-rich repeat ECR1_N PF14382.6 PRP84681.1 - 0.085 12.7 35.0 6.2 6.7 0.1 11.5 12 1 0 12 12 12 0 Exosome complex exonuclease RRP4 N-terminal region WD40 PF00400.32 PRP84682.1 - 5.5e-35 118.8 11.8 1.5e-09 38.3 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84682.1 - 4e-14 52.7 0.2 0.0034 17.6 0.0 5.3 1 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP84682.1 - 1.3e-08 34.2 0.3 0.31 10.0 0.1 4.9 2 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP84682.1 - 4.5e-06 25.6 1.2 0.71 8.4 0.1 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PRP84682.1 - 0.0019 17.0 0.0 1.2 7.7 0.0 3.2 1 1 1 3 3 3 1 Nup133 N terminal like PALB2_WD40 PF16756.5 PRP84682.1 - 0.054 12.4 0.0 0.14 11.0 0.0 1.8 1 1 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain YtkA PF13115.6 PRP84682.1 - 0.13 12.9 0.0 0.47 11.1 0.0 1.9 2 0 0 2 2 2 0 YtkA-like PepSY_like PF11396.8 PRP84682.1 - 0.16 12.6 0.1 7.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Putative beta-lactamase-inhibitor-like, PepSY-like V-ATPase_H_N PF03224.14 PRP84683.1 - 2.2e-67 227.6 5.4 2.2e-67 227.6 5.4 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 PRP84683.1 - 1e-38 132.1 0.5 1e-38 132.1 0.5 2.5 2 1 1 3 3 3 1 V-ATPase subunit H HEAT_2 PF13646.6 PRP84683.1 - 4e-05 23.9 0.1 0.097 13.1 0.0 3.4 3 1 0 3 3 3 2 HEAT repeats Arm PF00514.23 PRP84683.1 - 8.2e-05 22.5 1.5 0.39 10.8 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PRP84683.1 - 0.0012 19.0 0.0 0.77 10.2 0.0 3.2 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.6 PRP84683.1 - 0.0039 17.7 0.0 4.2 8.0 0.0 3.2 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 PRP84683.1 - 0.051 13.6 8.2 0.16 12.0 0.1 3.8 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Vps51 PF08700.11 PRP84683.1 - 0.55 10.4 3.8 0.64 10.1 0.6 2.6 3 0 0 3 3 3 0 Vps51/Vps67 RRM_1 PF00076.22 PRP84684.1 - 2.8e-21 75.1 0.0 5.7e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 PRP84684.1 - 1.5e-15 57.4 3.8 1.5e-15 57.4 3.8 2.2 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 PRP84684.1 - 5.1e-10 38.8 9.6 1.4e-09 37.4 9.6 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 PRP84684.1 - 0.025 14.7 0.2 0.12 12.5 0.0 2.3 3 0 0 3 3 3 0 RNA recognition motif DUF5103 PF17116.5 PRP84684.1 - 0.13 11.6 0.5 0.19 11.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) Carb_bind PF10645.9 PRP84685.1 - 0.0025 18.0 4.3 0.0025 18.0 4.3 4.5 4 1 1 5 5 5 2 Carbohydrate binding DUF1691 PF07950.11 PRP84685.1 - 0.049 14.3 0.9 8 7.2 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) zf-Tim10_DDP PF02953.15 PRP84686.1 - 1.9e-06 27.4 0.1 3.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Caenor_Her-1 PF09232.10 PRP84686.1 - 0.052 13.7 1.1 0.053 13.7 1.0 1.3 1 1 0 1 1 1 0 Caenorhabditis elegans Her-1 Cytomega_TRL10 PF06084.11 PRP84686.1 - 0.09 12.8 0.6 0.12 12.3 0.2 1.5 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein PA26 PF04636.13 PRP84687.1 - 6e-120 401.1 0.8 1.1e-119 400.3 0.8 1.4 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) zf-C3HC4 PF00097.25 PRP84687.1 - 3.4e-08 33.2 10.8 6e-08 32.4 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PWI PF01480.17 PRP84687.1 - 5.9e-06 26.5 2.3 1.2e-05 25.5 0.4 2.5 3 0 0 3 3 2 1 PWI domain zf-RING_2 PF13639.6 PRP84687.1 - 1.9e-05 24.9 12.4 3.6e-05 24.0 12.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP84687.1 - 0.00012 21.9 12.9 0.00021 21.1 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP84687.1 - 0.00012 21.8 7.6 0.0002 21.2 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP84687.1 - 0.00066 19.9 9.0 0.0015 18.8 9.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PRP84687.1 - 0.004 17.2 5.7 0.0091 16.0 5.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FAM76 PF16046.5 PRP84687.1 - 0.03 13.7 1.9 0.078 12.3 1.9 1.8 1 0 0 1 1 1 0 FAM76 protein zf-RING_UBOX PF13445.6 PRP84687.1 - 0.065 13.3 12.4 0.15 12.2 12.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 PRP84687.1 - 0.072 13.1 10.2 0.13 12.2 10.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPR_20 PF14561.6 PRP84687.1 - 0.072 13.4 0.2 0.2 12.0 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 PRP84687.1 - 0.21 11.8 11.1 0.58 10.4 11.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PRP84687.1 - 2.1 8.3 11.2 28 4.7 11.8 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Sec2p PF06428.11 PRP84687.1 - 2.7 8.0 6.2 1.3 9.0 2.5 2.5 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Cluap1 PF10234.9 PRP84688.1 - 2.5e-102 341.9 11.1 3.1e-102 341.6 11.1 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Ndc80_HEC PF03801.13 PRP84688.1 - 0.00035 20.2 0.0 0.0011 18.6 0.0 1.8 1 1 0 1 1 1 1 HEC/Ndc80p family Atg14 PF10186.9 PRP84688.1 - 0.012 14.7 5.0 0.016 14.3 4.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 PRP84688.1 - 0.25 11.0 15.1 0.55 9.9 15.1 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.8 PRP84688.1 - 0.33 11.0 16.8 0.017 15.2 4.6 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding LigB PF02900.18 PRP84689.1 - 6.4e-33 114.0 0.0 9.1e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase HNH_2 PF13391.6 PRP84689.1 - 0.003 17.7 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Prominin PF05478.11 PRP84691.1 - 4.8e-09 34.8 7.3 7e-07 27.6 5.3 2.4 1 1 1 2 2 2 2 Prominin Tweety PF04906.13 PRP84691.1 - 0.00062 18.5 25.9 0.0022 16.8 20.5 3.2 2 1 0 2 2 2 1 Tweety Pex24p PF06398.11 PRP84691.1 - 0.00072 18.6 2.3 0.0012 17.9 2.3 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin ETRAMP PF09716.10 PRP84691.1 - 0.23 11.6 2.0 2 8.5 0.0 3.1 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF3040 PF11239.8 PRP84691.1 - 2.4 8.5 9.0 0.64 10.3 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF846 PF05832.12 PRP84691.1 - 4.9 7.2 10.5 0.3 11.1 4.2 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) zf-U1 PF06220.12 PRP84692.1 - 6.9e-06 25.7 1.3 1.3e-05 24.8 1.3 1.5 1 0 0 1 1 1 1 U1 zinc finger DUF1033 PF06279.11 PRP84692.1 - 0.42 10.8 5.8 0.56 10.4 2.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1033) zf-C2H2_jaz PF12171.8 PRP84692.1 - 5.7 7.4 8.7 5.2 7.5 5.5 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RNase_PH PF01138.21 PRP84693.1 - 2.5e-35 121.9 0.0 3.3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pro_isomerase PF00160.21 PRP84694.1 - 6.1e-48 163.1 0.2 7e-48 162.9 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 PRP84695.1 - 4e-21 74.6 0.3 6.9e-18 64.2 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP84695.1 - 0.00012 22.1 0.0 0.023 14.8 0.0 3.2 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 PRP84695.1 - 0.034 14.1 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Erv26 PF04148.13 PRP84696.1 - 1.6e-33 116.3 7.6 8.1e-33 114.0 7.6 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 CreD PF06123.12 PRP84696.1 - 4.5 5.9 7.1 6 5.5 7.1 1.2 1 0 0 1 1 1 0 Inner membrane protein CreD HypA PF01155.19 PRP84697.1 - 0.015 15.3 0.4 0.021 14.8 0.4 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cas_TM1802 PF09484.10 PRP84697.1 - 0.054 12.2 0.3 0.09 11.5 0.3 1.3 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) EGF_2 PF07974.13 PRP84699.1 - 0.1 13.0 9.7 0.23 11.9 9.7 1.6 1 0 0 1 1 1 0 EGF-like domain Flavin_Reduct PF01613.18 PRP84700.1 - 1.1e-17 64.5 0.0 1.6e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Sec23_trunk PF04811.15 PRP84702.1 - 3.7e-71 239.5 1.1 6.7e-71 238.7 0.7 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PRP84702.1 - 4.1e-19 69.1 0.0 1.2e-18 67.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 PRP84702.1 - 9e-17 60.8 0.2 1.9e-16 59.7 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PRP84702.1 - 5.2e-13 48.8 4.6 1.2e-12 47.6 4.6 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 PRP84702.1 - 0.00014 21.7 0.0 0.00041 20.2 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Zn_ribbon_recom PF13408.6 PRP84702.1 - 0.069 13.7 4.5 7.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain C1_2 PF03107.16 PRP84702.1 - 0.079 13.3 0.8 0.19 12.1 0.8 1.6 1 0 0 1 1 1 0 C1 domain SAP PF02037.27 PRP84703.1 - 0.00013 21.6 2.5 0.00013 21.6 2.5 1.8 2 0 0 2 2 2 1 SAP domain DENN PF02141.21 PRP84704.1 - 4.3e-44 150.7 4.0 9.9e-44 149.5 4.0 1.6 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PRP84704.1 - 3.9e-11 43.5 1.8 3.9e-11 43.5 1.8 2.4 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 PRP84704.1 - 3.9e-08 33.2 0.9 1.1e-07 31.7 0.9 1.8 1 0 0 1 1 1 1 dDENN domain Leu_Phe_trans PF03588.14 PRP84704.1 - 0.19 11.2 0.2 0.34 10.4 0.2 1.3 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase DUF3818 PF12825.7 PRP84705.1 - 2.3e-29 102.5 5.3 2.5e-28 99.1 5.3 2.2 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Sigma70_r4_2 PF08281.12 PRP84705.1 - 0.59 9.8 2.6 38 4.1 0.2 3.5 3 0 0 3 3 3 0 Sigma-70, region 4 tRNA-synt_1g PF09334.11 PRP84707.1 - 3.9e-100 335.3 0.4 1e-99 333.9 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (M) SPA PF08616.10 PRP84707.1 - 5.5e-31 106.9 0.0 1.2e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis tRNA-synt_1 PF00133.22 PRP84707.1 - 1.1e-27 96.6 2.7 1.2e-13 50.3 0.2 3.8 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) Afi1 PF07792.12 PRP84707.1 - 1.3e-24 87.2 0.0 1.9e-23 83.4 0.0 2.5 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 PRP84707.1 - 2.1e-13 49.7 0.2 0.00015 20.6 0.0 3.4 2 1 1 3 3 3 3 Transport protein Avl9 DUF2347 PF09804.9 PRP84707.1 - 3.7e-11 43.2 0.0 4.6e-07 29.7 0.1 2.8 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) tRNA-synt_1e PF01406.19 PRP84707.1 - 6.5e-10 38.8 0.0 0.00051 19.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 PRP84707.1 - 0.0098 15.9 0.0 0.072 13.0 0.0 2.6 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 PRP84707.1 - 0.034 13.1 0.0 0.085 11.8 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (K) ICMT PF04140.14 PRP84708.1 - 1.1e-27 96.2 0.8 1.1e-27 96.2 0.8 2.0 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 PRP84708.1 - 1.3e-10 41.6 5.4 2.2e-10 40.9 3.8 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 PRP84708.1 - 3.4e-05 23.5 1.4 4.4e-05 23.1 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 PRP84708.1 - 3.6e-05 23.4 0.6 4.4e-05 23.1 0.6 1.3 1 0 0 1 1 1 1 NnrU protein ERG4_ERG24 PF01222.17 PRP84708.1 - 5.2e-05 22.2 1.4 5.2e-05 22.2 1.4 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family SLATT_5 PF18160.1 PRP84708.1 - 0.0091 15.3 1.7 0.016 14.6 0.1 1.8 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain family 5 FxsA PF04186.13 PRP84708.1 - 0.035 14.2 0.2 0.035 14.2 0.2 1.7 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein DUF1427 PF07235.11 PRP84708.1 - 0.098 12.6 0.0 0.098 12.6 0.0 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1427) HemY_N PF07219.13 PRP84708.1 - 0.82 9.9 3.2 8.9 6.6 0.5 2.3 2 0 0 2 2 2 0 HemY protein N-terminus DUF4133 PF13571.6 PRP84708.1 - 1.3 9.4 6.9 8.5 6.8 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) DUF3093 PF11292.8 PRP84708.1 - 9.3 6.5 7.4 12 6.2 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) ENT PF03735.14 PRP84710.1 - 3.4e-17 62.3 0.8 1.7e-16 60.0 0.8 2.2 1 0 0 1 1 1 1 ENT domain MMR_HSR1 PF01926.23 PRP84710.1 - 1.2e-05 25.3 0.0 0.0049 16.9 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 PRP84710.1 - 0.00016 22.2 0.9 0.0024 18.4 0.0 3.5 3 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 PRP84710.1 - 0.00038 20.4 0.5 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 PRP84710.1 - 0.0022 17.7 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein NB-ARC PF00931.22 PRP84710.1 - 0.014 14.6 0.2 0.25 10.5 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain DUF4485 PF14846.6 PRP84710.1 - 0.029 14.4 0.2 0.091 12.8 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) AAA_29 PF13555.6 PRP84710.1 - 0.044 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PRP84710.1 - 0.1 12.9 0.2 0.67 10.2 0.0 2.5 2 0 0 2 2 1 0 AAA domain Mu-like_Com PF10122.9 PRP84710.1 - 0.2 11.1 0.6 0.48 9.9 0.6 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com Cytochrom_B562 PF07361.11 PRP84710.1 - 1.7 9.4 13.0 0.59 10.8 3.0 3.9 3 0 0 3 3 3 0 Cytochrome b562 Cytochrome_C7 PF14522.6 PRP84710.1 - 2.6 8.1 9.7 4.2 7.4 6.2 3.1 3 1 0 3 3 2 0 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 PRP84710.1 - 3.4 8.2 10.3 5.1 7.6 7.5 2.8 1 1 1 2 2 2 0 Cytochrome c3 Mito_carr PF00153.27 PRP84711.1 - 7.6e-33 112.3 1.1 2.4e-18 65.8 0.0 3.9 3 1 1 4 4 4 3 Mitochondrial carrier protein AAA PF00004.29 PRP84712.1 - 3.9e-56 189.1 0.1 9.1e-38 129.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 PRP84712.1 - 3.5e-09 37.0 0.1 2.3e-06 27.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PRP84712.1 - 4.8e-09 36.6 1.6 0.0013 19.0 0.0 3.9 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 PRP84712.1 - 4.3e-08 32.8 0.0 0.00074 18.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_lid_3 PF17862.1 PRP84712.1 - 4.9e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PRP84712.1 - 7.4e-08 32.5 0.0 0.00071 19.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP84712.1 - 1.1e-07 32.4 0.2 0.0099 16.3 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 PRP84712.1 - 4e-07 30.7 0.0 0.011 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 PRP84712.1 - 5.9e-07 29.4 0.1 0.023 14.5 0.1 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 PRP84712.1 - 1.2e-06 28.3 0.1 0.00022 21.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP84712.1 - 5.4e-06 26.8 0.0 0.036 14.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 PRP84712.1 - 7.4e-06 25.5 0.6 0.0071 15.8 0.2 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PRP84712.1 - 7.4e-06 26.2 0.0 0.06 13.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 PRP84712.1 - 8.7e-06 25.8 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PRP84712.1 - 2.7e-05 24.2 1.3 0.078 12.9 0.0 3.5 3 1 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.17 PRP84712.1 - 3.1e-05 23.8 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 PRP84712.1 - 4.7e-05 23.4 1.9 3 7.7 0.3 4.1 2 2 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 PRP84712.1 - 5e-05 22.9 0.3 1 8.9 0.0 3.5 2 1 0 3 3 3 2 AAA domain TsaE PF02367.17 PRP84712.1 - 0.00011 22.2 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 PRP84712.1 - 0.00012 21.9 0.0 0.014 15.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PRP84712.1 - 0.00018 21.1 0.1 0.022 14.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 PRP84712.1 - 0.00019 21.2 0.0 0.62 9.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 PRP84712.1 - 0.00019 20.9 0.1 0.22 11.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ATPase PF06745.13 PRP84712.1 - 0.00041 19.8 1.6 0.011 15.1 0.1 3.0 2 1 1 3 3 3 1 KaiC AAA_28 PF13521.6 PRP84712.1 - 0.00071 19.8 0.0 0.83 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 PRP84712.1 - 0.0012 18.5 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain ResIII PF04851.15 PRP84712.1 - 0.0024 17.9 0.0 0.29 11.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 PRP84712.1 - 0.0027 18.2 0.1 0.17 12.4 0.1 2.7 2 0 0 2 2 2 1 ABC transporter DUF2075 PF09848.9 PRP84712.1 - 0.0029 16.9 0.2 1.5 8.0 0.1 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 PRP84712.1 - 0.0037 17.2 0.2 4.1 7.3 0.1 3.4 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_11 PF13086.6 PRP84712.1 - 0.005 16.7 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain IPT PF01745.16 PRP84712.1 - 0.012 15.0 0.0 0.44 9.9 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Viral_helicase1 PF01443.18 PRP84712.1 - 0.013 15.2 0.0 0.26 11.0 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 PRP84712.1 - 0.014 14.6 0.2 4.4 6.4 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 PRP84712.1 - 0.017 15.5 0.6 2.1 8.7 0.2 3.5 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.17 PRP84712.1 - 0.03 13.4 0.0 0.89 8.6 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SRPRB PF09439.10 PRP84712.1 - 0.034 13.6 0.0 0.72 9.3 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CDC48_2 PF02933.17 PRP84712.1 - 0.038 13.8 0.2 0.58 10.0 0.0 2.4 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 SRP54 PF00448.22 PRP84712.1 - 0.047 13.3 0.0 9.1 5.8 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 PRP84712.1 - 0.055 13.9 0.5 17 5.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 PRP84712.1 - 0.066 12.4 0.1 7.4 5.6 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Bac_DnaA PF00308.18 PRP84712.1 - 0.086 12.7 0.0 2.4 8.0 0.0 2.5 3 0 0 3 3 2 0 Bacterial dnaA protein Clathrin PF00637.20 PRP84713.1 - 0.0097 15.8 0.4 0.27 11.1 0.1 2.7 2 1 0 2 2 2 1 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 PRP84715.1 - 5.5e-11 41.9 15.0 1.9e-10 40.2 15.0 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 PRP84715.1 - 1.6e-09 38.2 16.8 0.07 14.0 0.4 7.3 8 0 0 8 8 8 3 WD domain, G-beta repeat zinc_ribbon_16 PF17034.5 PRP84715.1 - 5.2e-05 23.5 13.3 0.00067 19.9 13.3 2.5 1 1 0 1 1 1 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 PRP84715.1 - 0.0013 19.0 1.4 2.2 8.6 0.1 3.6 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain RWD PF05773.22 PRP84715.1 - 0.002 18.4 0.0 0.0057 16.9 0.0 1.8 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 PRP84715.1 - 0.096 13.0 5.7 0.48 10.8 5.7 2.3 1 0 0 1 1 1 0 Ring finger domain Zn_clus PF00172.18 PRP84715.1 - 2.7 8.2 5.6 0.73 10.0 1.3 2.3 2 1 1 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNase-RNase PF02577.14 PRP84716.1 - 0.054 13.1 0.1 0.41 10.3 0.1 2.2 2 1 0 2 2 2 0 Bifunctional nuclease Ank_2 PF12796.7 PRP84717.1 - 8.3e-29 100.0 5.4 5.4e-11 42.9 1.6 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84717.1 - 2.6e-28 98.0 0.1 7.9e-11 42.3 0.0 5.5 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP84717.1 - 1.9e-21 75.5 1.9 1.7e-05 25.1 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PRP84717.1 - 2.2e-18 66.1 0.0 0.00015 22.0 0.1 5.1 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84717.1 - 8.7e-17 59.5 0.1 0.0013 19.0 0.1 6.8 7 0 0 7 7 7 4 Ankyrin repeat CBM9_1 PF06452.11 PRP84717.1 - 0.11 12.4 2.4 0.4 10.6 0.2 2.3 2 0 0 2 2 2 0 Carbohydrate family 9 binding domain-like Meth_synt_2 PF01717.18 PRP84718.1 - 3.3e-146 486.7 0.0 2.3e-139 464.2 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 PRP84718.1 - 8.9e-126 419.6 0.1 1.1e-117 393.0 0.1 3.0 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain UCH PF00443.29 PRP84718.1 - 1.2e-55 188.8 1.0 5.3e-55 186.7 0.6 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP84718.1 - 1.5e-32 113.5 2.9 5.1e-32 111.7 2.9 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_4 PF18036.1 PRP84718.1 - 0.026 14.6 1.1 10 6.2 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin-like domain TBK1_ULD PF18396.1 PRP84718.1 - 0.039 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 PRP84718.1 - 0.067 13.0 6.0 22 4.9 0.0 4.4 4 0 0 4 4 4 0 Ubiquitin family Sod_Cu PF00080.20 PRP84720.1 - 4.3e-58 195.5 9.2 1.3e-30 106.4 0.6 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) CD36 PF01130.21 PRP84721.1 - 3.8e-68 230.1 2.5 7e-47 160.0 0.0 2.1 2 0 0 2 2 2 2 CD36 family DUF3040 PF11239.8 PRP84721.1 - 0.0038 17.4 2.2 0.4 11.0 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3040) DUF872 PF05915.12 PRP84721.1 - 0.043 14.0 0.3 0.65 10.2 0.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Radial_spoke_3 PF06098.11 PRP84722.1 - 2.4e-50 171.4 17.5 2.4e-50 171.4 17.5 2.0 1 1 1 2 2 2 1 Radial spoke protein 3 PGM_PMM_I PF02878.16 PRP84723.1 - 1.1e-36 125.5 0.0 2.3e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 PRP84723.1 - 6.4e-26 91.0 0.0 1.5e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 PRP84723.1 - 1.4e-14 54.2 0.0 2.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 PRP84723.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RGS PF00615.19 PRP84725.1 - 3e-20 72.7 1.5 4.3e-20 72.2 1.5 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain NAPRTase_N PF17767.1 PRP84726.1 - 3e-40 137.5 0.0 2.6e-39 134.5 0.0 2.2 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 PRP84726.1 - 1.3e-26 93.2 0.1 2.9e-26 92.1 0.1 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 PRP84726.1 - 1.3e-12 47.9 0.0 1.4e-05 24.8 0.0 2.2 1 1 1 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Chlam_PMP PF02415.17 PRP84727.1 - 0.67 10.6 5.5 3.2 8.4 0.2 3.4 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ephrin_rec_like PF07699.13 PRP84727.1 - 1.9 8.3 10.0 7.5 6.4 1.8 3.0 2 0 0 2 2 2 0 Putative ephrin-receptor like Fibrinogen_BP PF08017.11 PRP84728.1 - 8.9e-08 31.0 55.0 8.9e-08 31.0 55.0 3.1 1 1 2 3 3 3 2 Fibrinogen binding protein Mcl1_mid PF12341.8 PRP84729.1 - 7.6e-59 199.5 0.3 4e-58 197.1 0.0 2.4 3 0 0 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 PRP84729.1 - 1.3e-21 76.5 19.4 5e-06 27.1 0.0 10.0 9 1 1 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84729.1 - 5.2e-13 49.1 1.7 0.00028 21.1 0.1 6.8 2 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP84729.1 - 0.00065 18.8 0.1 0.23 10.4 0.0 2.9 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP84729.1 - 0.0037 17.2 0.7 0.083 12.8 0.1 3.0 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 PRP84729.1 - 0.0093 15.3 0.0 0.3 10.4 0.0 2.5 1 1 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal DUF2894 PF11445.8 PRP84729.1 - 7 7.1 11.0 0.6 10.5 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) TLD PF07534.16 PRP84730.1 - 1.7e-40 138.5 0.3 4.5e-40 137.1 0.1 1.9 2 0 0 2 2 2 1 TLD LysM PF01476.20 PRP84730.1 - 2.7e-07 30.5 0.1 7.8e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 LysM domain WD40 PF00400.32 PRP84730.1 - 0.00015 22.5 2.9 1.8 9.6 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Ferritin PF00210.24 PRP84731.1 - 9.4e-16 58.0 1.4 1.3e-15 57.6 1.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain Spectrin PF00435.21 PRP84731.1 - 0.031 14.8 1.1 0.12 12.8 0.3 2.0 2 0 0 2 2 2 0 Spectrin repeat GPS PF01825.21 PRP84732.1 - 2.4e-09 37.5 5.4 6.1e-09 36.3 5.4 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Insulin_TMD PF17870.1 PRP84732.1 - 0.13 12.3 1.4 0.35 11.0 1.4 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DAP10 PF07213.11 PRP84732.1 - 2 8.4 4.2 0.83 9.7 0.2 2.5 3 0 0 3 3 3 0 DAP10 membrane protein COesterase PF00135.28 PRP84733.1 - 1.1e-07 31.1 0.0 1.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP84733.1 - 0.0011 18.9 0.1 0.0034 17.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold PalH PF08733.10 PRP84733.1 - 0.015 14.3 0.3 0.019 14.0 0.3 1.1 1 0 0 1 1 1 0 PalH/RIM21 Imm30 PF15565.6 PRP84734.1 - 0.061 13.4 0.0 7.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Immunity protein 30 PIP5K PF01504.18 PRP84735.1 - 1.4e-58 198.3 3.4 1.4e-58 198.3 3.4 2.5 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Asparaginase_2 PF01112.18 PRP84736.1 - 7.6e-77 258.3 0.3 9.1e-77 258.1 0.3 1.0 1 0 0 1 1 1 1 Asparaginase IlvC PF01450.19 PRP84736.1 - 0.18 12.1 0.4 1.5 9.1 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain Response_reg PF00072.24 PRP84738.1 - 1.8e-19 69.9 1.4 3.1e-19 69.2 0.2 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 PRP84738.1 - 1.4e-14 53.9 0.4 5.1e-14 52.1 0.0 2.3 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 PRP84738.1 - 1e-13 52.0 0.0 3.5e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP84738.1 - 2.9e-13 49.8 0.0 6.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain HATPase_c PF02518.26 PRP84738.1 - 6.8e-06 26.6 0.2 0.00023 21.7 0.2 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.6 PRP84738.1 - 0.00062 20.1 0.0 0.0071 16.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF3369 PF11849.8 PRP84738.1 - 0.00079 19.7 0.3 0.72 10.0 0.0 3.1 1 1 0 2 2 2 2 Domain of unknown function (DUF3369) Rad17 PF03215.15 PRP84738.1 - 0.014 15.3 0.1 0.091 12.7 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 PRP84738.1 - 0.026 13.7 0.0 0.87 8.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Ncstrn_small PF18266.1 PRP84738.1 - 0.029 14.4 0.6 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Nicastrin small lobe GAF_2 PF13185.6 PRP84738.1 - 0.042 14.1 0.0 0.15 12.3 0.0 2.0 1 0 0 1 1 1 0 GAF domain RsgA_GTPase PF03193.16 PRP84738.1 - 0.051 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 PRP84738.1 - 0.071 13.6 0.0 1.1 9.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.11 PRP84738.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain ECH_2 PF16113.5 PRP84739.1 - 8.7e-39 133.9 0.0 3e-38 132.2 0.0 1.9 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PRP84739.1 - 8.1e-13 48.3 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Myosin_head PF00063.21 PRP84739.1 - 1.4e-09 36.8 0.4 2.5e-09 36.0 0.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) WD40_like PF17005.5 PRP84739.1 - 2.2e-07 30.5 0.8 0.00032 20.1 0.1 2.4 2 0 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 PRP84739.1 - 0.00058 20.1 0.5 2.3 8.6 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP84739.1 - 0.016 16.1 9.8 2.9 8.9 0.2 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat MbeD_MobD PF04899.12 PRP84739.1 - 0.035 14.2 0.4 0.12 12.5 0.4 1.9 1 0 0 1 1 1 0 MbeD/MobD like Herpeto_peptide PF14409.6 PRP84739.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon PMBR PF09373.10 PRP84739.1 - 0.12 12.5 0.0 0.41 10.9 0.0 2.0 1 0 0 1 1 1 0 Pseudomurein-binding repeat partial_CstF PF15861.5 PRP84739.1 - 0.24 11.2 1.1 0.98 9.2 1.1 2.0 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain nsp8 PF08717.10 PRP84740.1 - 0.1 12.4 0.4 19 5.0 0.1 2.8 3 0 0 3 3 3 0 nsp8 replicase HATPase_c PF02518.26 PRP84742.1 - 2.1e-25 89.4 0.1 4.8e-25 88.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP84742.1 - 9.7e-23 80.5 1.7 1.6e-22 79.8 0.3 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 PRP84742.1 - 1.3e-14 53.9 0.4 4.8e-14 52.2 0.0 2.3 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 PRP84742.1 - 9.8e-14 52.1 0.0 3.2e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP84742.1 - 2.7e-13 49.9 0.0 6.1e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain AAA_22 PF13401.6 PRP84742.1 - 0.00054 20.2 0.0 0.0067 16.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF3369 PF11849.8 PRP84742.1 - 0.00086 19.5 0.3 0.68 10.1 0.0 2.9 1 1 0 2 2 2 2 Domain of unknown function (DUF3369) Rad17 PF03215.15 PRP84742.1 - 0.013 15.4 0.1 0.086 12.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 PRP84742.1 - 0.023 13.9 0.0 0.82 8.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain GAF_2 PF13185.6 PRP84742.1 - 0.034 14.4 0.0 0.14 12.4 0.0 2.2 1 0 0 1 1 1 0 GAF domain RsgA_GTPase PF03193.16 PRP84742.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 PRP84742.1 - 0.068 13.7 0.0 1.1 9.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Ncstrn_small PF18266.1 PRP84742.1 - 0.091 12.8 0.5 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Nicastrin small lobe AAA_PrkA PF08298.11 PRP84742.1 - 0.098 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain Asparaginase_2 PF01112.18 PRP84744.1 - 1.8e-76 257.1 0.2 2.2e-76 256.8 0.2 1.0 1 0 0 1 1 1 1 Asparaginase PIP5K PF01504.18 PRP84745.1 - 1.6e-58 198.1 3.4 1.6e-58 198.1 3.4 2.5 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Eapp_C PF10238.9 PRP84745.1 - 0.29 11.2 2.0 0.65 10.1 2.0 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein LRRFIP PF09738.9 PRP84746.1 - 0.6 9.5 11.5 0.038 13.5 6.0 1.7 2 0 0 2 2 2 0 LRRFIP family VitD-bind_III PF09164.10 PRP84747.1 - 0.025 14.5 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Abhydrolase_3 PF07859.13 PRP84749.1 - 6.9e-07 29.3 0.5 2.1e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP84749.1 - 0.00012 21.7 0.2 0.039 13.4 0.1 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 PRP84749.1 - 0.011 15.4 0.1 0.036 13.7 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) COesterase PF00135.28 PRP84749.1 - 0.017 14.1 0.1 0.4 9.5 0.0 2.3 2 0 0 2 2 2 0 Carboxylesterase family Focal_AT PF03623.13 PRP84749.1 - 0.026 14.5 0.2 0.076 13.0 0.0 1.9 2 0 0 2 2 2 0 Focal adhesion targeting region LIDHydrolase PF10230.9 PRP84749.1 - 0.03 13.9 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 PRP84749.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 PRP84749.1 - 0.082 12.2 0.0 0.18 11.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 PRP84750.1 - 2.7e-58 197.3 0.0 4.8e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84750.1 - 9.5e-52 176.0 0.0 1.6e-51 175.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 PRP84750.1 - 6.1e-35 119.7 0.4 8.7e-10 39.1 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP84750.1 - 1e-30 105.3 4.1 2.7e-09 37.1 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP84750.1 - 6.1e-23 80.9 4.7 2.1e-06 28.1 0.2 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP84750.1 - 3.3e-17 62.1 5.5 0.011 16.1 1.1 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.6 PRP84750.1 - 1.6e-15 55.7 1.5 0.0027 18.1 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat SAM_2 PF07647.17 PRP84750.1 - 6.4e-13 48.6 0.0 1.7e-12 47.3 0.0 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP84750.1 - 4.4e-09 36.7 0.0 1e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-PARP PF00645.18 PRP84750.1 - 0.00011 23.0 0.2 0.00031 21.6 0.2 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Kinase-like PF14531.6 PRP84750.1 - 0.00037 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP84750.1 - 0.0019 17.2 0.0 0.0043 16.0 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP84750.1 - 0.0031 16.9 0.1 0.0075 15.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP84750.1 - 0.015 14.1 0.0 0.032 13.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PRP84750.1 - 0.2 11.2 0.3 2.2 7.8 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Myb_DNA-binding PF00249.31 PRP84752.1 - 0.00022 21.3 0.0 0.00038 20.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Transformer PF06495.11 PRP84752.1 - 0.047 13.8 1.9 0.097 12.8 1.9 1.6 1 0 0 1 1 1 0 Fruit fly transformer protein Peptidase_C13 PF01650.18 PRP84753.1 - 2.9e-40 138.4 0.4 4.7e-40 137.7 0.4 1.3 1 0 0 1 1 1 1 Peptidase C13 family PQQ_2 PF13360.6 PRP84753.1 - 0.012 15.2 0.0 0.058 13.0 0.0 1.9 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 PRP84753.1 - 0.033 15.1 1.6 0.15 13.0 0.1 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat ArgoMid PF16487.5 PRP84753.1 - 0.061 13.6 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute Sulfate_transp PF00916.20 PRP84755.1 - 2.1e-101 339.5 22.5 2.8e-101 339.0 22.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PRP84755.1 - 1.4e-19 69.8 0.1 4.1e-19 68.3 0.1 1.8 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 PRP84755.1 - 0.00072 19.9 14.8 0.0012 19.2 3.8 3.2 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily RTA1 PF04479.13 PRP84756.1 - 3.5e-61 206.4 3.2 3.5e-61 206.4 3.2 2.3 2 1 0 2 2 2 1 RTA1 like protein Actin PF00022.19 PRP84757.1 - 3e-23 82.1 0.0 3.9e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Actin Mito_carr PF00153.27 PRP84759.1 - 4.4e-60 199.6 6.9 8.6e-22 76.9 0.1 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein TM2 PF05154.16 PRP84759.1 - 6.3e-13 48.8 0.8 6.3e-13 48.8 0.8 2.6 2 0 0 2 2 2 1 TM2 domain EGF_2 PF07974.13 PRP84759.1 - 0.00026 21.3 8.8 0.00057 20.2 8.8 1.6 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 PRP84759.1 - 0.023 15.0 7.6 0.053 13.8 7.6 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 PRP84759.1 - 0.064 13.9 5.0 0.18 12.5 5.0 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_alliinase PF04863.13 PRP84759.1 - 0.23 11.9 5.4 0.58 10.6 5.4 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain RAP1 PF07218.11 PRP84759.1 - 0.31 9.3 0.0 0.41 8.9 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EGF_Tenascin PF18720.1 PRP84759.1 - 3.4 7.8 8.4 13 5.9 7.1 2.5 2 1 0 2 2 2 0 Tenascin EGF domain Abhydrolase_3 PF07859.13 PRP84760.1 - 2.9e-27 95.9 0.2 8.1e-27 94.4 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PRP84760.1 - 1.5e-21 76.8 0.2 5.1e-21 75.1 0.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 PRP84760.1 - 9.6e-07 28.0 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 PRP84760.1 - 8.5e-06 25.4 0.5 2.9e-05 23.7 0.5 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PRP84760.1 - 6.5e-05 22.3 0.3 0.042 13.1 0.0 2.8 2 1 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 PRP84760.1 - 0.0003 20.5 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 PRP84760.1 - 0.00051 19.5 1.5 0.098 12.0 0.1 2.2 1 1 1 2 2 2 2 Secretory lipase Esterase_phd PF10503.9 PRP84760.1 - 0.00063 19.3 0.0 0.34 10.4 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Chlorophyllase PF07224.11 PRP84760.1 - 0.0048 16.0 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_1 PF00561.20 PRP84760.1 - 0.014 15.1 0.1 0.18 11.5 0.2 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 PRP84761.1 - 6.4e-63 210.9 0.0 3.3e-31 108.0 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) DUF676 PF05057.14 PRP84761.1 - 5.3e-05 22.8 0.0 0.38 10.2 0.0 2.4 2 0 0 2 2 2 2 Putative serine esterase (DUF676) DUF452 PF04301.13 PRP84761.1 - 0.0022 17.5 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF452) Abhydrolase_6 PF12697.7 PRP84761.1 - 0.035 14.7 0.0 13 6.3 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3390 PF11870.8 PRP84761.1 - 0.051 13.9 0.5 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) Prok-RING_2 PF14445.6 PRP84761.1 - 0.24 11.6 6.9 6.1 7.1 0.7 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 zf-Sec23_Sec24 PF04810.15 PRP84761.1 - 0.33 11.1 3.3 13 5.9 0.2 2.6 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger FeoB_associated PF12669.7 PRP84761.1 - 0.34 11.4 1.8 1.3 9.4 1.8 2.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Abhydrolase_1 PF00561.20 PRP84761.1 - 0.34 10.5 1.5 30 4.1 0.1 3.0 3 0 0 3 3 3 0 alpha/beta hydrolase fold PHD_4 PF16866.5 PRP84761.1 - 0.59 10.3 5.0 27 4.9 0.1 3.7 4 0 0 4 4 4 0 PHD-finger zf-RanBP PF00641.18 PRP84761.1 - 1.4 8.3 4.4 19 4.7 0.2 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF551 PF04448.12 PRP84761.1 - 5.8 7.9 6.3 8 7.5 0.7 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF551) Glyco_hydro_3_C PF01915.22 PRP84764.1 - 2.5e-52 177.8 0.0 3.6e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PRP84764.1 - 2.6e-39 135.5 0.0 6.8e-39 134.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 PRP84764.1 - 2.7e-19 69.4 0.0 5.9e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 PRP84764.1 - 3e-14 52.9 0.3 8.2e-14 51.5 0.3 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 PRP84764.1 - 0.007 16.6 1.0 0.042 14.1 1.0 2.2 1 1 0 1 1 1 1 Domain of unknown function DUF11 Peptidase_C48 PF02902.19 PRP84765.1 - 8.7e-35 120.5 0.0 1.5e-34 119.8 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CPSF100_C PF13299.6 PRP84765.1 - 0.85 9.8 9.9 0.99 9.6 3.8 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 PRP84765.1 - 1.1 9.6 8.8 0.75 10.1 3.7 2.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.12 PRP84765.1 - 1.2 8.4 19.9 0.13 11.7 11.8 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Afi1 PF07792.12 PRP84765.1 - 1.6 9.2 7.5 2.1 8.8 2.4 2.5 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking RNA_pol_Rpc4 PF05132.14 PRP84765.1 - 5.9 7.3 8.5 1.1 9.7 1.4 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 G8 PF10162.9 PRP84766.1 - 1.4e-19 70.4 0.4 3.1e-19 69.3 0.4 1.6 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP84766.1 - 0.00028 20.8 4.5 0.005 16.7 0.5 3.7 1 1 2 3 3 3 1 Right handed beta helix region Adap_comp_sub PF00928.21 PRP84767.1 - 3.4e-89 298.7 0.1 3.4e-89 298.7 0.1 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family LOH1CR12 PF10158.9 PRP84767.1 - 1.4e-10 41.3 0.1 3.6e-10 40.0 0.1 1.7 1 0 0 1 1 1 1 Tumour suppressor protein Clat_adaptor_s PF01217.20 PRP84767.1 - 0.00032 20.7 0.4 0.00088 19.2 0.4 1.7 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NPR3 PF03666.13 PRP84767.1 - 0.04 12.7 13.7 0.072 11.9 13.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 PRP84767.1 - 0.31 10.4 25.6 0.63 9.4 25.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BSP_II PF05432.11 PRP84767.1 - 0.68 9.6 39.4 1.2 8.7 39.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 PRP84767.1 - 0.75 8.0 21.6 1.1 7.5 21.6 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 PRP84768.1 - 3.5e-23 81.4 21.7 0.00011 22.9 0.1 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84768.1 - 0.00037 20.7 2.4 1.6 9.1 0.1 3.7 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP84768.1 - 0.035 12.8 1.1 1.2 7.7 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Gal_GalNac_35kD PF17337.2 PRP84768.1 - 0.036 14.1 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Galactose-inhibitable lectin 35 kDa subunit Nucleoporin_N PF08801.11 PRP84768.1 - 0.11 11.2 0.7 6.6 5.4 0.1 2.6 1 1 1 2 2 2 0 Nup133 N terminal like WD40 PF00400.32 PRP84769.1 - 1.2e-30 105.1 6.4 1.5e-05 25.7 0.0 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 PRP84769.1 - 9.1e-07 27.9 0.1 0.0041 15.8 0.1 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Spc7 PF08317.11 PRP84769.1 - 0.0002 20.4 8.7 0.00031 19.8 8.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ANAPC4_WD40 PF12894.7 PRP84769.1 - 0.00055 20.2 0.1 11 6.4 0.0 4.2 3 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain ADIP PF11559.8 PRP84769.1 - 0.00056 20.0 9.6 0.0011 19.1 9.6 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 PRP84769.1 - 0.0027 17.7 3.8 0.0056 16.7 3.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Fcf1 PF04900.12 PRP84769.1 - 0.014 15.8 1.1 0.91 10.0 0.0 3.3 3 0 0 3 3 3 0 Fcf1 AAA_11 PF13086.6 PRP84769.1 - 0.015 15.1 2.8 0.031 14.0 2.8 1.5 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.11 PRP84769.1 - 0.017 15.3 5.2 0.027 14.7 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) hDGE_amylase PF14701.6 PRP84769.1 - 0.037 13.1 3.3 0.054 12.6 3.3 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF1515 PF07439.11 PRP84769.1 - 0.058 13.4 2.3 0.88 9.6 2.3 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF1515) DUF3450 PF11932.8 PRP84769.1 - 0.088 12.1 5.9 0.15 11.4 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 PRP84769.1 - 0.12 12.4 0.7 0.24 11.4 0.7 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.13 PRP84769.1 - 0.13 11.5 4.8 0.2 10.9 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sec34 PF04136.15 PRP84769.1 - 0.15 12.0 4.4 0.28 11.1 4.4 1.4 1 0 0 1 1 1 0 Sec34-like family BLOC1_2 PF10046.9 PRP84769.1 - 0.2 12.0 4.5 0.35 11.2 3.9 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 PRP84769.1 - 0.23 10.0 7.4 0.33 9.5 7.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_13 PF13166.6 PRP84769.1 - 0.24 10.0 8.7 0.34 9.5 8.7 1.1 1 0 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.24 PRP84769.1 - 0.39 10.6 5.2 0.96 9.4 5.1 1.7 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD V_ATPase_I PF01496.19 PRP84769.1 - 0.39 8.6 4.5 0.52 8.2 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3552 PF12072.8 PRP84769.1 - 0.4 10.1 14.0 0.64 9.4 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TLE_N PF03920.15 PRP84769.1 - 0.45 10.6 3.4 0.92 9.6 3.4 1.5 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain zf-C4H2 PF10146.9 PRP84769.1 - 0.49 10.7 6.6 0.88 9.8 6.6 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Prefoldin_2 PF01920.20 PRP84769.1 - 0.66 10.0 16.1 1.4 8.9 4.9 3.8 3 1 1 4 4 4 0 Prefoldin subunit UPF0242 PF06785.11 PRP84769.1 - 0.94 9.5 9.5 1.6 8.8 9.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 PRP84769.1 - 1.7 9.1 18.5 2.6 8.5 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 PRP84769.1 - 2 8.9 14.2 1.6 9.3 12.2 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 PRP84769.1 - 2.4 8.6 8.8 4.4 7.7 8.8 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4140 PF13600.6 PRP84769.1 - 8.6 6.9 6.3 9.2 6.8 0.3 2.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Redoxin PF08534.10 PRP84770.1 - 5e-32 110.6 0.1 5.5e-32 110.5 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PRP84770.1 - 1.7e-10 40.9 0.0 2.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family AIG1 PF04548.16 PRP84770.1 - 0.058 12.7 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 AIG1 family AhpC-TSA_2 PF13911.6 PRP84770.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme BTB PF00651.31 PRP84771.1 - 1.5e-27 96.0 0.5 1.7e-13 50.7 0.0 3.5 2 1 1 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 PRP84771.1 - 4.4e-08 33.6 0.1 9.4e-08 32.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84771.1 - 7.6e-07 29.6 0.0 2.2e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84771.1 - 1.5e-06 28.1 0.0 0.015 15.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 PRP84771.1 - 0.0035 17.7 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 PRP84771.1 - 0.025 14.9 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AAA PF00004.29 PRP84772.1 - 1.2e-15 58.1 0.0 2.7e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP84772.1 - 3e-06 27.6 0.1 0.00013 22.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PRP84772.1 - 1.7e-05 24.8 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 PRP84772.1 - 0.0005 19.9 2.0 0.0056 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP84772.1 - 0.0008 19.8 0.0 0.0008 19.8 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain Nop14 PF04147.12 PRP84772.1 - 0.0038 15.5 11.8 0.0055 15.0 11.8 1.1 1 0 0 1 1 1 1 Nop14-like family AAA_19 PF13245.6 PRP84772.1 - 0.014 15.8 0.1 0.64 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP84772.1 - 0.014 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PRP84772.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RXT2_N PF08595.11 PRP84772.1 - 0.034 14.2 3.8 0.086 12.9 3.8 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal AAA_33 PF13671.6 PRP84772.1 - 0.041 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 PRP84772.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 PRP84772.1 - 0.069 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 PRP84772.1 - 0.097 12.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DNA_pol_phi PF04931.13 PRP84772.1 - 0.12 10.5 17.0 0.21 9.7 17.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 PRP84772.1 - 0.23 10.9 13.6 0.42 10.0 13.6 1.3 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 PRP84772.1 - 0.37 9.7 12.1 0.64 9.0 12.1 1.3 1 0 0 1 1 1 0 Paf1 TFB6 PF17110.5 PRP84772.1 - 0.49 10.1 4.1 4.8 6.9 5.3 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH AAA_28 PF13521.6 PRP84772.1 - 0.62 10.3 0.0 0.62 10.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain TRAP_alpha PF03896.16 PRP84772.1 - 1.4 8.1 6.8 3.1 6.9 6.8 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.8 PRP84772.1 - 1.8 7.4 6.9 3 6.7 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CobT PF06213.12 PRP84772.1 - 2.7 7.3 16.9 4.9 6.5 16.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RPN2_C PF18004.1 PRP84772.1 - 4.5 7.2 6.7 13 5.6 6.7 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 PRP84772.1 - 5.6 5.1 12.3 9.3 4.4 12.3 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 PRP84772.1 - 5.7 6.2 15.4 9.8 5.4 15.4 1.3 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 PRP84772.1 - 8.4 6.1 9.8 20 4.9 9.8 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Na_K-ATPase PF00287.18 PRP84773.1 - 0.006 15.8 2.0 0.023 13.8 1.5 2.2 2 0 0 2 2 2 1 Sodium / potassium ATPase beta chain EGF_2 PF07974.13 PRP84774.1 - 0.046 14.1 9.1 0.085 13.3 9.1 1.4 1 0 0 1 1 1 0 EGF-like domain Na_K-ATPase PF00287.18 PRP84774.1 - 1.2 8.2 3.8 1.7 7.7 1.9 2.0 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain Ribosomal_L18 PF17135.4 PRP84775.1 - 0.00075 18.9 0.2 0.00079 18.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Kinesin PF00225.23 PRP84776.1 - 4.8e-77 259.1 2.7 6.3e-77 258.7 2.7 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PRP84776.1 - 2.4e-17 63.2 0.0 4.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF3258 PF11646.8 PRP84776.1 - 0.11 12.7 0.1 0.3 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF3258 CAP PF00188.26 PRP84777.1 - 9.4e-20 71.7 5.8 9.4e-20 71.7 5.8 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family X8 PF07983.13 PRP84777.1 - 1e-12 48.6 1.3 1e-12 48.6 1.3 2.3 1 1 2 3 3 3 1 X8 domain Git3 PF11710.8 PRP84779.1 - 6.6e-07 29.3 11.0 6.6e-07 29.3 11.0 2.5 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 PRP84779.1 - 4.2e-06 26.1 11.2 5.5e-06 25.7 11.2 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7TM_GPCR_Srv PF10323.9 PRP84779.1 - 0.0006 19.3 1.5 0.0006 19.3 1.5 1.9 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srv GPR_Gpa2_C PF11970.8 PRP84779.1 - 0.0015 18.6 0.2 0.0015 18.6 0.2 2.2 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term UPF0542 PF15086.6 PRP84779.1 - 0.0076 16.2 3.6 0.017 15.1 2.0 2.3 3 0 0 3 3 3 1 Uncharacterised protein family UPF0542 DUF2269 PF10027.9 PRP84779.1 - 0.22 11.6 6.5 1.1 9.3 0.8 2.4 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) HemY_N PF07219.13 PRP84779.1 - 0.74 10.0 2.3 0.72 10.1 0.3 1.9 2 0 0 2 2 2 0 HemY protein N-terminus DUF4190 PF13828.6 PRP84779.1 - 8.2 6.3 8.7 0.24 11.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) TRP PF06011.12 PRP84780.1 - 0.0029 16.4 28.0 0.013 14.3 16.5 3.4 1 1 1 3 3 3 3 Transient receptor potential (TRP) ion channel Na_Ca_ex PF01699.24 PRP84780.1 - 0.78 9.7 16.5 1.8 8.5 0.1 3.9 2 1 1 4 4 4 0 Sodium/calcium exchanger protein RRM_1 PF00076.22 PRP84782.1 - 1.2e-16 60.3 0.1 1.8e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 PRP84782.1 - 0.0056 16.6 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 RL domain RRM_Rrp7 PF17799.1 PRP84782.1 - 0.0084 15.9 0.0 1.8 8.4 0.0 2.2 1 1 1 2 2 2 2 Rrp7 RRM-like N-terminal domain CCD48 PF15799.5 PRP84782.1 - 0.012 13.9 0.9 0.015 13.6 0.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 WD40_alt PF14077.6 PRP84782.1 - 0.018 14.9 3.0 0.044 13.6 3.0 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif NRBF2 PF08961.10 PRP84782.1 - 0.019 14.6 0.6 0.028 14.1 0.6 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator GldM_N PF12081.8 PRP84782.1 - 0.031 14.4 0.8 0.041 14.0 0.8 1.3 1 0 0 1 1 1 0 GldM N-terminal domain Rho_GDI PF02115.17 PRP84782.1 - 0.041 13.6 0.8 0.057 13.1 0.8 1.2 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor RRM_7 PF16367.5 PRP84782.1 - 0.054 13.6 0.0 0.37 10.9 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif Fmp27_WPPW PF10359.9 PRP84782.1 - 0.079 11.8 1.4 0.078 11.8 1.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PI3K_P85_iSH2 PF16454.5 PRP84782.1 - 0.096 12.3 4.3 0.15 11.6 4.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Nup35_RRM_2 PF14605.6 PRP84782.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CENP-O PF09496.10 PRP84782.1 - 0.18 11.8 2.6 0.2 11.6 2.6 1.3 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Fzo_mitofusin PF04799.13 PRP84782.1 - 0.2 11.2 1.3 0.29 10.7 1.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region ATG7_N PF16420.5 PRP84782.1 - 0.22 11.1 0.9 0.34 10.5 0.9 1.3 1 0 0 1 1 1 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus V_ATPase_I PF01496.19 PRP84782.1 - 0.64 7.9 1.8 0.72 7.7 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LigA PF07746.11 PRP84783.1 - 0.046 13.9 0.1 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 Aromatic-ring-opening dioxygenase LigAB, LigA subunit PepX_N PF09168.10 PRP84783.1 - 0.13 12.7 2.2 0.21 12.0 1.7 1.6 1 1 1 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal Band_7 PF01145.25 PRP84784.1 - 3.8e-24 85.7 0.8 5.7e-24 85.1 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Peptidase_S66 PF02016.15 PRP84784.1 - 0.074 13.2 0.2 0.16 12.1 0.2 1.6 1 1 0 1 1 1 0 LD-carboxypeptidase N-terminal domain DUF1098 PF06497.11 PRP84784.1 - 0.13 12.8 0.2 0.26 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1098) SET PF00856.28 PRP84785.1 - 2e-12 47.8 0.1 6.1e-12 46.3 0.1 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 PRP84785.1 - 2.2e-11 43.7 13.2 2.2e-11 43.7 13.2 2.9 2 0 0 2 2 2 1 MYND finger FAM177 PF14774.6 PRP84786.1 - 1.8e-07 31.6 0.0 3.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 FAM177 family SH3_9 PF14604.6 PRP84787.1 - 2.2e-14 53.0 0.1 3.9e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP84787.1 - 3.3e-13 49.0 0.0 6.9e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP84787.1 - 4.4e-08 32.7 0.0 8.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Allexi_40kDa PF05549.11 PRP84787.1 - 0.23 11.0 3.2 0.68 9.4 1.1 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF948 PF06103.11 PRP84787.1 - 0.57 10.5 4.1 1 9.7 0.4 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PPR_2 PF13041.6 PRP84791.1 - 7.2e-48 160.6 5.8 2.7e-08 33.9 0.1 8.5 5 3 3 8 8 8 8 PPR repeat family PPR_3 PF13812.6 PRP84791.1 - 7.6e-37 125.2 0.6 8.6e-06 25.7 0.0 8.7 5 2 3 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.20 PRP84791.1 - 2.3e-19 68.2 7.7 0.00052 20.1 0.4 6.7 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 PRP84791.1 - 4.1e-14 52.4 2.1 5e-07 29.3 0.0 4.1 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP84791.1 - 2.3e-09 36.8 0.7 0.067 12.9 0.0 6.8 7 0 0 7 7 7 2 PPR repeat RPM2 PF08579.11 PRP84791.1 - 4.1e-06 27.2 0.4 1.9 8.9 0.1 5.2 5 2 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) Exog_C PF18026.1 PRP84791.1 - 3.5e-05 23.8 3.1 6.8 6.8 0.0 6.5 7 0 0 7 7 7 1 Endo/exonuclease (EXOG) C-terminal domain BKACE PF05853.12 PRP84791.1 - 0.0071 15.7 2.0 0.73 9.1 0.0 3.1 1 1 2 3 3 3 2 beta-keto acid cleavage enzyme Amidoligase_2 PF12224.8 PRP84791.1 - 0.0083 15.8 0.1 0.07 12.8 0.0 2.4 1 1 1 2 2 2 1 Putative amidoligase enzyme HTH_31 PF13560.6 PRP84791.1 - 0.01 16.2 0.7 0.025 14.9 0.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Vac_ImportDeg PF09783.9 PRP84791.1 - 0.022 14.6 0.0 0.067 13.0 0.0 1.9 1 1 0 1 1 1 0 Vacuolar import and degradation protein LpxI_N PF17930.1 PRP84791.1 - 0.3 11.0 1.6 6.2 6.7 0.0 3.6 5 0 0 5 5 5 0 LpxI N-terminal domain TPR_14 PF13428.6 PRP84791.1 - 0.63 11.0 8.4 41 5.4 1.5 5.4 4 2 2 6 6 6 0 Tetratricopeptide repeat Prenyltransf PF01255.19 PRP84793.1 - 2.6e-07 30.4 0.0 2.6e-07 30.4 0.0 1.7 2 1 0 2 2 2 1 Putative undecaprenyl diphosphate synthase DUF2834 PF11196.8 PRP84795.1 - 0.064 13.6 0.6 0.12 12.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) BRAP2 PF07576.12 PRP84797.1 - 0.018 15.2 0.0 0.022 15.0 0.0 1.0 1 0 0 1 1 1 0 BRCA1-associated protein 2 F_actin_bund_C PF18060.1 PRP84799.1 - 4.1e-09 36.4 11.0 4.1e-09 36.4 11.0 2.8 1 1 1 2 2 2 1 F actin bundling C terminal DUF4045 PF13254.6 PRP84799.1 - 0.051 13.2 10.9 0.064 12.9 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) KxDL PF10241.9 PRP84799.1 - 0.12 12.7 10.4 0.78 10.1 0.2 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein DUF2968 PF11180.8 PRP84799.1 - 0.3 10.7 17.0 0.032 13.9 11.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) SesA PF17107.5 PRP84799.1 - 0.51 10.5 8.8 0.11 12.7 4.7 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF16 PF01519.16 PRP84799.1 - 3.9 8.0 13.5 1 9.9 7.6 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 HycH PF07450.11 PRP84799.1 - 6.5 7.1 6.4 4.1 7.8 2.0 2.5 2 1 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH Ank_2 PF12796.7 PRP84800.1 - 0.0053 17.3 0.0 0.06 13.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box-like PF12937.7 PRP84800.1 - 0.045 13.6 2.6 0.11 12.4 1.0 2.4 3 0 0 3 3 3 0 F-box-like F-box PF00646.33 PRP84800.1 - 0.079 12.9 1.7 0.46 10.4 1.7 2.3 1 0 0 1 1 1 0 F-box domain Metallophos PF00149.28 PRP84802.1 - 1.8e-33 116.8 0.5 3.7e-33 115.8 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PHA_gran_rgn PF09650.10 PRP84803.1 - 0.0025 18.0 0.2 0.0072 16.6 0.0 1.8 2 0 0 2 2 2 1 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) ELFV_dehydrog_N PF02812.18 PRP84803.1 - 0.0059 16.5 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain XS PF03468.14 PRP84803.1 - 0.015 15.6 0.4 0.83 10.0 0.1 2.1 1 1 1 2 2 2 0 XS domain Exo_endo_phos_2 PF14529.6 PRP84803.1 - 0.031 14.1 2.2 0.36 10.7 0.1 2.6 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase G8 PF10162.9 PRP84804.1 - 0.014 15.4 0.4 0.075 13.1 0.1 2.5 2 1 0 2 2 2 0 G8 domain Amnionless PF14828.6 PRP84804.1 - 0.17 10.7 0.0 1 8.1 0.0 1.9 2 0 0 2 2 2 0 Amnionless Insulin_TMD PF17870.1 PRP84805.1 - 0.026 14.6 3.0 0.057 13.5 3.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Paramecium_SA PF01508.16 PRP84805.1 - 0.03 14.8 7.7 0.051 14.0 7.7 1.4 1 0 0 1 1 1 0 Paramecium surface antigen domain EphA2_TM PF14575.6 PRP84805.1 - 0.09 13.7 0.0 0.09 13.7 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 PRP84805.1 - 0.22 11.0 0.1 0.3 10.6 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) PSI PF01437.25 PRP84805.1 - 0.46 11.1 8.0 0.77 10.3 8.0 1.4 1 0 0 1 1 1 0 Plexin repeat Glyco_hydro_76 PF03663.14 PRP84806.1 - 3.9e-21 76.0 1.1 6.8e-21 75.2 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 zf-C2HC_2 PF13913.6 PRP84806.1 - 6.6e-11 41.8 23.6 1.8e-06 27.7 0.5 4.9 5 0 0 5 5 5 3 zinc-finger of a C2HC-type RicinB_lectin_2 PF14200.6 PRP84806.1 - 1.6e-08 35.1 9.0 2.9e-06 27.9 0.8 4.9 3 1 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like PAN_4 PF14295.6 PRP84806.1 - 4.7e-08 32.8 2.6 1.1e-07 31.7 2.6 1.7 1 0 0 1 1 1 1 PAN domain PH PF00169.29 PRP84806.1 - 3.3e-06 27.5 0.1 1.4e-05 25.5 0.1 2.0 1 0 0 1 1 1 1 PH domain Fascin PF06268.13 PRP84806.1 - 0.0019 18.4 0.1 5.5 7.2 0.0 3.6 3 0 0 3 3 3 2 Fascin domain Glyco_hydro_88 PF07470.13 PRP84806.1 - 0.0062 15.6 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 zf-C2HE PF16278.5 PRP84806.1 - 0.029 14.8 4.5 32 5.1 0.1 4.5 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 PRP84806.1 - 0.091 12.4 7.3 5.1 6.8 0.1 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Actin_micro PF17003.5 PRP84806.1 - 0.14 11.3 0.1 21 4.1 0.0 2.2 1 1 1 2 2 2 0 Putative actin-like family PAN_2 PF08276.11 PRP84806.1 - 0.47 10.6 3.9 1.9 8.7 3.9 2.0 1 0 0 1 1 1 0 PAN-like domain GYF_2 PF14237.6 PRP84807.1 - 0.15 11.9 0.4 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 GYF domain 2 Nucleo_P87 PF07267.11 PRP84808.1 - 0.13 11.1 1.5 0.19 10.5 1.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DeoC PF01791.9 PRP84809.1 - 0.033 13.8 0.1 0.06 12.9 0.1 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase DoxX PF07681.12 PRP84809.1 - 0.057 14.0 6.5 0.14 12.8 5.5 2.2 2 0 0 2 2 2 0 DoxX PP2C_2 PF13672.6 PRP84810.1 - 2.8e-05 23.9 0.0 3.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PRP84810.1 - 0.00059 19.8 0.1 0.0014 18.6 0.1 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 PRP84810.1 - 0.022 14.4 0.1 0.14 11.7 0.0 2.0 1 1 1 2 2 2 0 Protein phosphatase 2C TYA PF01021.19 PRP84810.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 TYA transposon protein Mito_carr PF00153.27 PRP84811.1 - 1.8e-63 210.5 1.2 1.4e-24 85.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PRP84811.1 - 0.0077 15.4 0.2 0.035 13.3 0.0 2.0 3 0 0 3 3 3 1 Gammaproteobacterial serine protease NDUF_B6 PF09782.9 PRP84811.1 - 0.084 13.0 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Putative_PNPOx PF01243.20 PRP84812.1 - 8e-12 45.2 0.0 8.2e-11 41.9 0.0 2.1 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.25 PRP84813.1 - 8e-48 163.1 0.1 6e-27 94.6 0.3 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84813.1 - 2.8e-19 69.4 0.0 2.5e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PRP84813.1 - 3.4e-05 23.9 0.1 0.00076 19.5 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP84813.1 - 0.0037 16.6 0.1 0.0064 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP84813.1 - 0.0049 16.5 0.1 0.0087 15.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 PRP84813.1 - 0.05 12.9 0.0 8.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 PRP84813.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DSPc PF00782.20 PRP84815.1 - 7.2e-27 93.8 0.0 1.2e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain GATA PF00320.27 PRP84815.1 - 2.6e-09 36.6 6.3 6.6e-09 35.2 6.3 1.8 1 0 0 1 1 1 1 GATA zinc finger Y_phosphatase PF00102.27 PRP84815.1 - 0.0042 16.7 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pyr_redox_2 PF07992.14 PRP84816.1 - 1.2e-45 156.0 0.0 2e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 PRP84816.1 - 1.2e-12 46.4 2.3 2.5e-05 23.5 0.3 2.8 2 0 0 2 2 2 2 EF hand Pyr_redox PF00070.27 PRP84816.1 - 2.4e-11 44.0 0.0 4.1e-09 36.9 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 PRP84816.1 - 3.6e-10 40.1 0.8 1.1e-09 38.6 0.8 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP84816.1 - 4.6e-10 38.6 0.4 0.00032 20.4 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PRP84816.1 - 1.1e-08 34.1 5.0 4.2e-05 22.8 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PRP84816.1 - 2.7e-06 27.1 0.3 0.014 15.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair F-box PF00646.33 PRP84816.1 - 0.081 12.8 0.3 0.41 10.6 0.1 2.3 2 0 0 2 2 2 0 F-box domain EF-hand_10 PF14788.6 PRP84816.1 - 0.2 11.5 0.6 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 EF hand Acetyltransf_1 PF00583.25 PRP84817.1 - 2.3e-12 47.2 0.0 3.2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP84817.1 - 7.8e-05 23.0 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP84817.1 - 0.0034 17.5 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP84817.1 - 0.054 13.4 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arg_repressor PF01316.21 PRP84817.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain MFS_1 PF07690.16 PRP84818.1 - 2e-44 152.0 48.9 2.7e-43 148.2 35.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PRP84818.1 - 3.1e-13 49.1 16.4 5.7e-09 35.0 2.5 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 PRP84818.1 - 3e-11 42.9 27.1 1.8e-10 40.3 2.1 4.1 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 PRP84818.1 - 6.5e-09 35.1 29.6 5.8e-05 22.1 3.6 3.8 1 1 1 3 3 3 3 MFS_1 like family MFS_4 PF06779.14 PRP84818.1 - 7.1e-05 22.3 15.9 0.0021 17.4 1.2 2.8 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB UNC-93 PF05978.16 PRP84818.1 - 0.00084 19.1 3.2 0.00084 19.1 3.2 2.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 OATP PF03137.20 PRP84818.1 - 0.87 7.8 14.2 0.03 12.6 1.6 2.9 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family BacteriocIIc_cy PF12173.8 PRP84818.1 - 0.94 9.8 5.8 2.9 8.2 0.1 3.0 2 1 1 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like TMEM132D_C PF15706.5 PRP84818.1 - 4.1 7.2 5.4 0.35 10.7 0.4 1.8 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2200 PF09966.9 PRP84819.1 - 0.18 12.0 0.0 0.25 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) Pkinase PF00069.25 PRP84820.1 - 2.5e-51 174.6 0.0 2.8e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84820.1 - 1.5e-19 70.3 0.0 2e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP84820.1 - 1.4e-05 25.2 0.3 5.2e-05 23.3 0.3 1.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP84820.1 - 5.7e-05 22.6 0.1 8.3e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP84820.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 PRP84820.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Dak2 PF02734.17 PRP84820.1 - 0.028 14.3 0.1 0.089 12.7 0.0 1.7 2 0 0 2 2 2 0 DAK2 domain FTA2 PF13095.6 PRP84820.1 - 0.04 13.5 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M41 PF01434.18 PRP84821.1 - 4.6e-58 196.2 8.5 1.3e-57 194.7 8.5 1.7 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PRP84821.1 - 4.6e-41 140.3 0.0 1.5e-40 138.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP84821.1 - 3.3e-09 36.4 0.2 1.4e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 PRP84821.1 - 7.2e-05 23.1 0.0 0.068 13.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PRP84821.1 - 0.0002 21.4 0.1 0.0008 19.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PRP84821.1 - 0.00022 20.6 0.3 0.0027 16.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 PRP84821.1 - 0.00023 21.6 0.3 0.0056 17.1 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PRP84821.1 - 0.002 17.9 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PRP84821.1 - 0.0068 16.5 1.0 0.09 12.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 PRP84821.1 - 0.014 15.1 0.0 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 PRP84821.1 - 0.018 14.4 0.3 0.37 10.1 0.0 2.5 3 0 0 3 3 3 0 KaiC TsaE PF02367.17 PRP84821.1 - 0.024 14.6 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 PRP84821.1 - 0.025 14.3 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 PRP84821.1 - 0.053 13.4 1.1 0.19 11.7 0.1 2.3 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.21 PRP84821.1 - 0.062 12.7 0.1 0.17 11.3 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PRP84821.1 - 0.068 13.2 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PRP84821.1 - 0.095 13.2 0.8 0.47 11.0 0.1 2.2 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 PRP84821.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 PRP84821.1 - 0.13 11.7 0.1 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 PRP84821.1 - 0.16 12.1 0.0 0.61 10.2 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain LAG1-DNAbind PF09271.11 PRP84824.1 - 0.05 14.2 0.0 0.075 13.7 0.0 1.3 1 0 0 1 1 1 0 LAG1, DNA binding DNA_pol_B_exo1 PF03104.19 PRP84824.1 - 0.22 10.6 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Tetraspanin PF00335.20 PRP84825.1 - 0.16 11.6 5.2 0.2 11.4 5.2 1.2 1 0 0 1 1 1 0 Tetraspanin family LEA_4 PF02987.16 PRP84826.1 - 1.5e-17 63.4 168.5 1.9e-06 27.9 19.5 10.1 2 2 8 10 10 10 8 Late embryogenesis abundant protein DUF883 PF05957.13 PRP84826.1 - 0.0018 18.9 92.1 0.34 11.5 11.0 5.6 1 1 4 5 5 5 3 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 PRP84826.1 - 0.017 15.6 10.4 0.017 15.6 10.4 6.7 1 1 4 5 5 5 0 YtxH-like protein Apolipoprotein PF01442.18 PRP84826.1 - 0.79 9.6 82.8 5.3 6.9 12.9 3.1 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain VCBS PF13517.6 PRP84827.1 - 7.8e-21 74.4 9.6 4e-08 33.7 1.5 5.8 5 0 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PRP84827.1 - 1.9e-13 50.3 12.6 0.0039 17.3 1.8 5.7 5 0 0 5 5 5 5 FG-GAP repeat BBS2_Mid PF14783.6 PRP84827.1 - 2.8e-05 24.1 4.3 17 5.5 0.0 6.4 7 0 0 7 7 7 1 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 PRP84827.1 - 0.0001 21.5 5.7 0.077 12.0 0.2 5.6 5 1 0 6 6 6 1 Integrin-alpha FG-GAP repeat-containing protein 2 PQQ_3 PF13570.6 PRP84827.1 - 0.00011 22.6 5.5 0.93 10.1 0.0 5.0 5 0 0 5 5 5 2 PQQ-like domain PQQ_2 PF13360.6 PRP84827.1 - 0.009 15.6 0.1 0.094 12.3 0.1 2.3 1 1 1 2 2 2 2 PQQ-like domain TcdB_toxin_midN PF12256.8 PRP84827.1 - 0.019 14.4 2.6 6.2 6.2 0.1 4.1 2 1 2 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region BBS2_C PF14782.6 PRP84827.1 - 0.02 13.7 0.5 0.75 8.5 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal OTU PF02338.19 PRP84827.1 - 0.075 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 OTU-like cysteine protease G8 PF10162.9 PRP84828.1 - 8.6e-19 67.8 0.3 1.6e-18 67.0 0.3 1.5 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP84828.1 - 2.3e-05 24.3 2.7 0.0018 18.1 0.0 3.3 2 1 1 3 3 3 1 Right handed beta helix region F-box-like PF12937.7 PRP84828.1 - 0.0083 16.0 0.7 0.023 14.6 0.7 1.7 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 PRP84828.1 - 0.11 13.1 0.0 0.41 11.3 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) F-box PF00646.33 PRP84828.1 - 0.23 11.4 1.1 0.56 10.1 1.1 1.6 1 0 0 1 1 1 0 F-box domain Carb_bind PF10645.9 PRP84829.1 - 6.1e-07 29.5 10.0 6.1e-07 29.5 10.0 2.8 2 0 0 2 2 2 1 Carbohydrate binding DUF676 PF05057.14 PRP84829.1 - 0.036 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Suv3_N PF18114.1 PRP84829.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Suv3 helical N-terminal domain Peptidase_M16_M PF16187.5 PRP84830.1 - 1e-72 244.8 0.2 1e-72 244.8 0.2 2.1 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 PRP84830.1 - 3.7e-40 137.3 0.3 3.7e-40 137.3 0.3 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PRP84830.1 - 3.4e-16 59.8 1.1 3e-14 53.5 0.0 3.7 3 1 0 3 3 3 1 Peptidase M16 inactive domain bZIP_1 PF00170.21 PRP84830.1 - 5.4e-08 32.8 13.9 1.5e-07 31.4 13.5 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PRP84830.1 - 8.2e-07 29.0 13.1 3e-06 27.2 13.1 2.0 1 1 0 1 1 1 1 Basic region leucine zipper YabA PF06156.13 PRP84830.1 - 0.0038 17.8 2.8 0.015 16.0 2.8 2.0 1 0 0 1 1 1 1 Initiation control protein YabA bZIP_Maf PF03131.17 PRP84830.1 - 0.015 15.8 7.4 0.015 15.8 7.4 2.2 1 1 0 1 1 1 0 bZIP Maf transcription factor APG6_N PF17675.1 PRP84830.1 - 0.21 12.1 10.8 3.8 8.1 11.9 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region Pox_Ag35 PF03286.14 PRP84830.1 - 3.4 7.4 18.7 0.046 13.5 7.8 2.4 1 1 1 2 2 2 0 Pox virus Ag35 surface protein CBM_20 PF00686.19 PRP84832.1 - 4e-12 45.9 1.0 1.5e-11 44.1 0.1 2.5 3 0 0 3 3 3 1 Starch binding domain zf-C3HC4_3 PF13920.6 PRP84832.1 - 3.7e-10 39.5 11.8 3.7e-10 39.5 11.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Beta_helix PF13229.6 PRP84832.1 - 1.6e-09 37.8 150.0 0.00026 20.9 12.9 8.2 1 1 6 7 7 7 6 Right handed beta helix region Prok-RING_4 PF14447.6 PRP84832.1 - 0.00032 20.5 13.5 0.00067 19.5 13.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Chlam_PMP PF02415.17 PRP84832.1 - 0.019 15.4 0.1 0.019 15.4 0.1 21.4 24 1 0 24 24 24 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TPP_enzyme_M_2 PF16582.5 PRP84832.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Middle domain of thiamine pyrophosphate zf-RING_5 PF14634.6 PRP84832.1 - 3.1 7.8 12.8 8.6 6.4 12.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Frag1 PF10277.9 PRP84833.1 - 7.8e-43 146.6 13.5 9e-43 146.3 13.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4271 PF14093.6 PRP84833.1 - 0.0098 15.8 2.9 0.0098 15.8 2.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4271) Ost5 PF05251.12 PRP84833.1 - 0.022 15.0 5.1 2.6 8.3 0.1 2.9 2 1 0 2 2 2 0 Oligosaccharyltransferase subunit 5 MFS_1 PF07690.16 PRP84833.1 - 0.05 12.5 13.7 0.051 12.5 11.9 1.9 1 1 0 1 1 1 0 Major Facilitator Superfamily Ninjurin PF04923.12 PRP84833.1 - 0.071 13.1 0.2 0.071 13.1 0.2 2.4 1 1 1 2 2 2 0 Ninjurin EcsB PF05975.12 PRP84833.1 - 0.51 9.1 8.8 0.024 13.5 3.4 1.6 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB DUF3040 PF11239.8 PRP84833.1 - 0.63 10.3 6.7 0.49 10.7 0.2 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3040) DUF3169 PF11368.8 PRP84833.1 - 0.72 9.3 8.6 0.038 13.5 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Cation_ATPase_C PF00689.21 PRP84833.1 - 0.79 9.4 10.3 0.33 10.6 4.9 2.2 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Sigma_reg_N PF13800.6 PRP84833.1 - 1.2 9.5 6.4 2.9 8.3 0.1 3.0 3 1 0 3 3 3 0 Sigma factor regulator N-terminal DUF2721 PF11026.8 PRP84833.1 - 1.5 8.7 8.6 6.5 6.6 6.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) SLATT_5 PF18160.1 PRP84833.1 - 4.4 6.6 5.9 10 5.4 2.6 2.3 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Caa3_CtaG PF09678.10 PRP84833.1 - 4.8 6.6 11.9 0.084 12.3 3.3 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Abhydrolase_9_N PF15420.6 PRP84833.1 - 5.7 6.9 8.3 9.5 6.2 0.6 2.7 1 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus Cation_ATPase_C PF00689.21 PRP84834.1 - 4.7e-47 160.0 2.7 4.7e-47 160.0 2.7 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PRP84834.1 - 1.7e-43 148.3 1.7 1.7e-43 148.3 1.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PRP84834.1 - 9.3e-23 81.6 0.1 4.5e-11 43.4 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP84834.1 - 3.7e-20 71.8 0.0 7.4e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PRP84834.1 - 9.8e-13 47.6 0.0 2.8e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PRP84834.1 - 4.2e-08 33.3 0.2 3e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PRP84834.1 - 0.16 12.4 0.0 24 5.3 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Nucleos_tra2_N PF01773.20 PRP84834.1 - 0.75 10.4 4.6 12 6.5 0.2 3.2 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus DnaJ_C PF01556.18 PRP84835.1 - 3.4e-40 137.5 0.3 5.1e-40 137.0 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PRP84835.1 - 1.1e-25 89.5 1.2 1.9e-25 88.7 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PRP84835.1 - 3.8e-13 49.6 18.8 6.7e-13 48.8 18.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 PRP84835.1 - 0.03 14.3 6.0 1.7 8.7 1.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 PRP84835.1 - 0.19 11.7 14.8 1.7 8.7 5.3 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 PRP84835.1 - 0.5 10.0 5.6 0.82 9.3 5.6 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf-RING_10 PF16685.5 PRP84835.1 - 5.9 7.1 5.9 4.6 7.5 0.8 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 E2F_CC-MB PF16421.5 PRP84837.1 - 3.9e-26 91.2 0.1 9.8e-26 90.0 0.1 1.7 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 PRP84837.1 - 5e-23 80.9 0.0 1e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain NDT80_PhoG PF05224.12 PRP84837.1 - 0.049 13.8 0.6 0.049 13.8 0.6 1.8 2 0 0 2 2 2 0 NDT80 / PhoG like DNA-binding family TrmB PF01978.19 PRP84837.1 - 0.16 11.8 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Caprin-1_C PF12287.8 PRP84837.1 - 0.8 9.8 8.6 1.6 8.8 8.6 1.4 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term F-box-like PF12937.7 PRP84839.1 - 8.7e-10 38.3 2.4 1.5e-09 37.6 2.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP84839.1 - 3.1e-07 30.1 2.3 5.9e-07 29.2 2.3 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP84839.1 - 0.0018 18.2 0.1 0.0042 16.9 0.1 1.5 1 0 0 1 1 1 1 F-box DUF740 PF05340.12 PRP84839.1 - 1.9 7.1 6.5 2.3 6.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) ADH_N PF08240.12 PRP84840.1 - 3.1e-17 62.4 5.1 5.9e-17 61.5 5.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PRP84840.1 - 1.1e-16 61.0 0.0 2.8e-16 59.7 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP84840.1 - 0.00055 21.0 0.0 0.00093 20.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 PRP84840.1 - 0.0014 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 PRP84840.1 - 0.027 13.8 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 PRP84840.1 - 0.034 13.4 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 PRP84840.1 - 0.037 13.7 0.1 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 PRP84840.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pkinase PF00069.25 PRP84841.1 - 6.2e-17 61.8 0.1 1.5e-16 60.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84841.1 - 1.2e-14 54.2 0.0 2.5e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 PRP84841.1 - 1.6e-05 25.0 0.0 4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pox_E6 PF04656.12 PRP84841.1 - 0.047 12.1 0.0 0.073 11.5 0.0 1.2 1 0 0 1 1 1 0 Pox virus E6 protein TFIIA PF03153.13 PRP84841.1 - 0.6 10.1 10.6 0.86 9.5 10.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 PRP84841.1 - 8.7 4.9 7.1 12 4.4 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TcdB_toxin_midN PF12256.8 PRP84842.1 - 0.018 14.4 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF2304 PF10066.9 PRP84842.1 - 0.054 13.7 0.2 0.33 11.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Snapin_Pallidin PF14712.6 PRP84843.1 - 9.9e-07 29.1 5.8 3.5e-05 24.1 3.5 2.6 2 1 0 2 2 2 1 Snapin/Pallidin GvpH PF05455.11 PRP84843.1 - 0.0069 16.5 0.1 0.0081 16.2 0.1 1.1 1 0 0 1 1 1 1 GvpH DUF2362 PF10154.9 PRP84843.1 - 0.13 11.2 5.7 0.17 10.8 5.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) DUF2937 PF11157.8 PRP84843.1 - 0.31 10.8 1.1 0.45 10.2 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) DUF1664 PF07889.12 PRP84843.1 - 0.33 11.0 3.3 0.53 10.3 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1690 PF07956.11 PRP84843.1 - 0.51 10.8 13.3 0.2 12.0 9.2 1.9 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Exonuc_VII_L PF02601.15 PRP84843.1 - 0.65 9.5 7.0 0.73 9.3 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SWIRM-assoc_1 PF16495.5 PRP84843.1 - 1.3 9.0 12.5 2.1 8.4 5.6 2.7 1 1 1 2 2 2 0 SWIRM-associated region 1 TMPIT PF07851.13 PRP84843.1 - 8.7 5.5 7.7 12 5.1 7.2 1.3 1 1 0 1 1 1 0 TMPIT-like protein RhoGEF PF00621.20 PRP84844.1 - 5.3e-45 153.9 2.1 1.3e-44 152.7 2.1 1.7 1 0 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 PRP84844.1 - 0.0062 16.5 0.0 0.03 14.3 0.0 2.2 2 0 0 2 2 2 1 PH domain Eapp_C PF10238.9 PRP84844.1 - 1.5 8.9 8.1 4.1 7.5 8.1 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein Zip PF02535.22 PRP84844.1 - 2.9 7.0 5.0 6 6.0 5.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter RPN2_C PF18004.1 PRP84844.1 - 3.9 7.4 21.4 17 5.3 21.4 2.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Guanylate_cyc PF00211.20 PRP84845.1 - 1.4e-15 57.4 0.2 5.8e-15 55.4 0.0 2.1 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Imm42 PF15593.6 PRP84845.1 - 0.82 10.1 0.0 0.82 10.1 0.0 3.3 3 0 0 3 3 3 0 Immunity protein 42 peroxidase PF00141.23 PRP84846.1 - 1.8e-46 158.7 0.0 3.1e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Pkinase PF00069.25 PRP84847.1 - 2.5e-48 164.7 0.1 1.8e-27 96.4 0.0 2.9 2 0 0 2 2 2 2 Protein kinase domain AAA_16 PF13191.6 PRP84847.1 - 1.1e-39 136.5 0.1 1.9e-38 132.5 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain Pkinase_Tyr PF07714.17 PRP84847.1 - 2.4e-23 82.7 0.0 1.2e-11 44.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 PRP84847.1 - 1e-21 77.2 0.2 2.7e-21 75.8 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 PRP84847.1 - 2.4e-18 66.7 0.2 6.8e-18 65.2 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WD40 PF00400.32 PRP84847.1 - 3.3e-15 56.2 3.1 2.4e-05 25.0 0.3 5.2 4 0 0 4 4 4 3 WD domain, G-beta repeat HisKA PF00512.25 PRP84847.1 - 6.3e-10 39.0 0.1 2.9e-09 36.8 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Kinase-like PF14531.6 PRP84847.1 - 1.1e-09 38.1 0.0 0.00018 21.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like GAF_2 PF13185.6 PRP84847.1 - 1.8e-07 31.6 0.0 5.7e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PRP84847.1 - 2.3e-07 31.5 0.0 6.1e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 PRP84847.1 - 0.0004 20.2 0.0 0.00098 19.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEAT PF02985.22 PRP84847.1 - 0.0011 19.0 8.4 1.4 9.4 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 PRP84847.1 - 0.0092 16.4 0.0 1.5 9.2 0.0 3.8 2 1 1 3 3 3 1 HEAT repeats RsgA_GTPase PF03193.16 PRP84847.1 - 0.026 14.4 0.2 0.092 12.6 0.1 2.0 2 0 0 2 2 1 0 RsgA GTPase GAF_3 PF13492.6 PRP84847.1 - 0.052 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 GAF domain NB-ARC PF00931.22 PRP84847.1 - 0.079 12.1 0.0 0.8 8.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ANAPC4_WD40 PF12894.7 PRP84847.1 - 0.081 13.2 0.2 33 4.9 0.0 3.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Kdo PF06293.14 PRP84847.1 - 0.1 11.9 3.8 0.82 9.0 0.3 2.7 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_EZ PF13513.6 PRP84847.1 - 0.11 13.0 0.2 0.39 11.3 0.2 2.0 1 0 0 1 1 1 0 HEAT-like repeat EAR PF07897.11 PRP84847.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression Beta_helix PF13229.6 PRP84848.1 - 1.5e-20 73.6 149.9 4.7e-08 33.0 25.5 8.0 1 1 7 8 8 8 8 Right handed beta helix region DisA_N PF02457.16 PRP84848.1 - 0.00072 19.1 0.1 2.2 7.9 0.0 3.9 3 0 0 3 3 3 2 DisA bacterial checkpoint controller nucleotide-binding TraO PF10626.9 PRP84848.1 - 0.0051 16.6 2.7 0.1 12.3 0.4 3.0 2 1 1 3 3 3 1 Conjugative transposon protein TraO Chlam_PMP PF02415.17 PRP84848.1 - 0.024 15.1 1.2 0.024 15.1 1.2 20.9 21 1 0 21 21 21 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat X8 PF07983.13 PRP84849.1 - 3.4e-10 40.5 2.2 3.4e-10 40.5 2.2 2.1 2 0 0 2 2 2 1 X8 domain Glyco_hydro_72 PF03198.14 PRP84849.1 - 0.00038 19.8 0.5 0.31 10.2 0.6 3.2 2 1 0 2 2 2 2 Glucanosyltransferase Carb_bind PF10645.9 PRP84849.1 - 0.0045 17.2 38.8 0.0058 16.8 11.2 4.5 3 1 1 4 4 4 2 Carbohydrate binding SPESP1 PF15754.5 PRP84849.1 - 2.7 7.1 5.0 5.8 6.0 5.0 1.5 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 PIGA PF08288.12 PRP84850.1 - 5.4e-40 135.9 2.1 6.3e-40 135.7 0.1 2.2 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 PRP84850.1 - 6.3e-29 101.2 0.0 9.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 PRP84850.1 - 4.7e-25 88.1 0.0 9.5e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PRP84850.1 - 2.9e-21 76.3 0.1 5.4e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PRP84850.1 - 8e-10 39.4 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 PRP84850.1 - 6.8e-06 26.2 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like ubiquitin PF00240.23 PRP84855.1 - 9.2e-06 25.3 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family C_GCAxxG_C_C PF09719.10 PRP84855.1 - 0.023 15.0 3.1 0.043 14.1 3.1 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) WD40 PF00400.32 PRP84856.1 - 1.9e-41 139.2 15.8 1.4e-08 35.2 0.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84856.1 - 3.1e-08 33.8 1.2 0.33 11.3 0.1 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP84856.1 - 0.00016 20.6 0.1 0.2 10.4 0.0 3.7 2 1 3 5 5 5 2 Nup133 N terminal like Frtz PF11768.8 PRP84856.1 - 0.00038 18.9 0.0 0.025 12.9 0.0 2.6 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz BBS2_Mid PF14783.6 PRP84856.1 - 0.00046 20.2 0.1 0.85 9.7 0.0 4.3 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 PRP84856.1 - 0.0023 16.6 0.7 12 4.4 0.0 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 B9-C2 PF07162.11 PRP84857.1 - 3.2e-53 180.4 0.1 3.6e-53 180.2 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ank_2 PF12796.7 PRP84858.1 - 1.8e-08 34.9 0.0 0.085 13.5 0.0 4.3 2 2 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84858.1 - 0.00044 20.8 2.2 20 5.9 0.0 6.4 7 1 0 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84858.1 - 0.00086 19.6 1.8 28 5.7 0.0 6.1 7 0 0 7 7 7 1 Ankyrin repeat F-box-like PF12937.7 PRP84858.1 - 0.016 15.1 0.5 0.042 13.8 0.5 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 PRP84858.1 - 0.031 14.2 0.2 0.067 13.1 0.2 1.5 1 0 0 1 1 1 0 F-box domain BORCS6 PF10157.9 PRP84859.1 - 5.8e-21 75.3 2.0 6.1e-21 75.2 2.0 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 ANAPC4 PF12896.7 PRP84859.1 - 3.9e-05 23.3 1.2 6e-05 22.6 0.7 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 T4SS PF07996.11 PRP84859.1 - 0.0031 17.9 1.2 0.0088 16.5 0.1 1.9 2 0 0 2 2 2 1 Type IV secretion system proteins Med7 PF05983.11 PRP84859.1 - 0.012 15.7 3.8 0.014 15.4 3.8 1.1 1 0 0 1 1 1 0 MED7 protein RPW8 PF05659.11 PRP84859.1 - 0.024 14.3 1.7 0.031 14.0 0.8 1.6 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BST2 PF16716.5 PRP84859.1 - 0.028 15.0 4.8 0.91 10.2 0.1 2.5 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DnaB_C PF03796.15 PRP84859.1 - 0.059 12.7 0.7 0.064 12.6 0.7 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NPV_P10 PF05531.12 PRP84859.1 - 0.12 12.9 1.6 0.26 11.8 0.4 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.13 PRP84859.1 - 0.14 11.7 2.9 0.21 11.1 2.7 1.4 1 1 0 1 1 1 0 fzo-like conserved region CENP-F_leu_zip PF10473.9 PRP84859.1 - 0.18 11.8 6.5 1.3 9.1 1.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DHR10 PF18595.1 PRP84859.1 - 0.26 11.4 4.7 0.29 11.2 1.6 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain V-ATPase_C PF03223.15 PRP84860.1 - 5.9e-117 391.2 12.7 7.3e-117 390.9 12.7 1.0 1 0 0 1 1 1 1 V-ATPase subunit C ASXH PF13919.6 PRP84860.1 - 0.69 9.9 4.6 4.6 7.3 0.0 2.6 3 0 0 3 3 3 0 Asx homology domain YtxH PF12732.7 PRP84860.1 - 3.5 8.2 5.1 33 5.1 0.0 3.6 4 0 0 4 4 4 0 YtxH-like protein Ctr PF04145.15 PRP84861.1 - 6e-19 69.1 4.5 6.8e-16 59.2 4.5 2.3 1 1 0 1 1 1 1 Ctr copper transporter family P5CR_dimer PF14748.6 PRP84862.1 - 2.3e-27 95.2 0.7 4.3e-27 94.4 0.7 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 PRP84862.1 - 8.7e-16 58.3 0.3 2.7e-15 56.7 0.3 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 PRP84862.1 - 3.7e-07 30.3 0.4 2.1e-06 27.8 0.4 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PDH PF02153.17 PRP84862.1 - 0.00041 19.4 0.2 0.00065 18.8 0.2 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Sacchrp_dh_NADP PF03435.18 PRP84862.1 - 0.0029 17.8 0.1 0.0063 16.8 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 PRP84862.1 - 0.0043 17.2 0.1 0.0072 16.5 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 PRP84862.1 - 0.057 13.1 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PEP-utilisers_N PF05524.13 PRP84862.1 - 0.072 13.3 0.4 0.21 11.8 0.4 1.9 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal RabGAP-TBC PF00566.18 PRP84863.1 - 1e-52 178.9 0.7 1.7e-52 178.2 0.7 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FYVE PF01363.21 PRP84863.1 - 4.7e-18 65.1 6.1 9.1e-18 64.2 6.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 PRP84863.1 - 0.00023 21.3 2.5 0.00055 20.1 2.5 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger PAS_8 PF13188.7 PRP84863.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain IBR PF01485.21 PRP84863.1 - 0.02 15.1 1.4 0.06 13.6 1.4 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PAS PF00989.25 PRP84863.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 PAS fold Ribosomal_L7Ae PF01248.26 PRP84864.1 - 4.1e-26 90.5 2.0 5e-26 90.3 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 PRP84864.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain UQ_con PF00179.26 PRP84866.1 - 5.2e-39 133.1 0.1 8.4e-39 132.4 0.0 1.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PRP84866.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B NPR2 PF06218.11 PRP84868.1 - 9.6e-84 281.7 9.1 2.4e-62 211.1 9.7 3.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 PRP84868.1 - 1.6e-07 30.5 1.6 0.0022 16.8 0.1 2.7 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 SLED PF12140.8 PRP84869.1 - 0.028 14.9 0.1 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 SLED domain NDK PF00334.19 PRP84870.1 - 2.1e-54 183.2 0.0 2.4e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 PRP84870.1 - 0.021 15.4 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ RhoGEF PF00621.20 PRP84871.1 - 1.3e-40 139.6 1.2 1.3e-40 139.6 1.2 2.3 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.29 PRP84871.1 - 5.6e-05 23.6 0.1 0.00019 21.9 0.1 1.9 1 0 0 1 1 1 1 PH domain MyTH4 PF00784.17 PRP84872.1 - 1.7e-12 47.8 0.3 1.8e-12 47.7 0.3 1.2 1 0 0 1 1 1 1 MyTH4 domain Metallophos PF00149.28 PRP84873.1 - 3.5e-17 63.6 0.2 6.7e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PRP84873.1 - 3.4e-13 50.0 0.0 1e-12 48.5 0.0 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3_PAP PF17808.1 PRP84873.1 - 8.7e-05 22.6 0.2 0.0005 20.2 0.2 2.3 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Metallophos_C PF14008.6 PRP84873.1 - 0.00021 22.1 0.4 0.00058 20.7 0.0 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C CBM_48 PF02922.18 PRP84873.1 - 0.032 14.6 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Cse1 PF08506.10 PRP84874.1 - 1.9e-115 385.6 4.9 1.9e-115 385.6 4.9 2.0 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 PRP84874.1 - 1.5e-101 340.1 0.8 1.5e-101 340.1 0.8 1.8 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 PRP84874.1 - 7.2e-12 45.0 0.2 6.5e-11 42.0 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 PRP84874.1 - 8e-05 22.7 1.6 8e-05 22.7 1.6 2.9 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 PRP84874.1 - 0.017 15.4 1.6 0.26 11.7 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat DUF3385 PF11865.8 PRP84874.1 - 0.19 11.6 2.6 0.49 10.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Tam41_Mmp37 PF09139.11 PRP84876.1 - 1.6e-98 330.1 0.4 1.9e-98 329.8 0.4 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial STAT_int PF02865.17 PRP84876.1 - 0.022 15.2 0.9 0.97 9.9 0.0 2.4 2 0 0 2 2 2 0 STAT protein, protein interaction domain RRM_1 PF00076.22 PRP84877.1 - 6.6e-10 38.7 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 PRP84877.1 - 1.8e-08 35.0 0.0 3.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 PRP84877.1 - 2.6e-07 30.5 2.5 6.2e-07 29.3 2.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_3 PF15663.5 PRP84877.1 - 0.0013 18.9 0.2 0.0036 17.5 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 PRP84877.1 - 0.0018 18.2 1.4 0.0018 18.2 1.4 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PRP84877.1 - 0.0026 17.5 2.5 0.0026 17.5 2.5 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger RRM_occluded PF16842.5 PRP84877.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-CCCH_2 PF14608.6 PRP84877.1 - 0.01 16.2 1.3 0.03 14.8 1.3 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 PRP84877.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.6 PRP84877.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PRP84877.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif FYVE PF01363.21 PRP84877.1 - 0.41 10.8 5.7 0.11 12.7 2.3 2.0 2 0 0 2 2 2 0 FYVE zinc finger Mod_r PF07200.13 PRP84878.1 - 1.1e-30 106.7 12.1 1.3e-30 106.4 12.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein WD40 PF00400.32 PRP84879.1 - 7.6e-16 58.2 11.5 0.00072 20.3 1.0 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84879.1 - 3.8e-05 23.9 1.5 0.12 12.7 0.1 4.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PRP84879.1 - 8.4e-05 22.9 2.3 3.3 8.3 0.0 5.1 4 1 1 5 5 5 1 PQQ-like domain Guanylate_kin PF00625.21 PRP84881.1 - 1e-36 126.4 0.3 3.4e-36 124.6 0.3 1.9 1 1 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 PRP84881.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_ab PF00006.25 PRP84882.1 - 2e-61 207.4 0.0 4.3e-61 206.3 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PRP84882.1 - 5.8e-21 74.8 0.2 1.2e-20 73.8 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 PRP84882.1 - 0.032 14.6 0.0 1.6 9.1 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 PRP84882.1 - 0.041 13.1 0.2 0.041 13.1 0.2 2.3 3 0 0 3 3 3 0 NB-ARC domain ATPase_2 PF01637.18 PRP84882.1 - 0.064 13.2 0.2 0.32 10.9 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 PRP84882.1 - 0.11 12.4 1.8 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 PRP84882.1 - 0.11 12.8 2.3 0.25 11.7 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain T3SS_ATPase_C PF18269.1 PRP84882.1 - 0.36 10.7 5.5 0.58 10.1 1.1 3.0 2 1 0 2 2 2 0 T3SS EscN ATPase C-terminal domain ABC_tran PF00005.27 PRP84882.1 - 3.1 8.3 5.6 0.94 10.0 0.2 2.5 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 PRP84882.1 - 3.5 7.9 7.3 0.39 11.1 0.2 2.8 4 0 0 4 4 4 0 AAA domain PseudoU_synth_2 PF00849.22 PRP84883.1 - 3.1e-30 105.4 0.2 4.9e-30 104.7 0.1 1.4 2 0 0 2 2 2 1 RNA pseudouridylate synthase PRP38 PF03371.15 PRP84884.1 - 1.3e-36 126.1 0.0 8.1e-36 123.5 0.0 1.9 1 1 0 1 1 1 1 PRP38 family DUF2457 PF10446.9 PRP84884.1 - 0.032 13.4 17.7 0.047 12.8 17.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4551 PF15087.6 PRP84884.1 - 2.7 6.7 8.0 3.3 6.4 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 PRP84884.1 - 8 4.6 10.6 9.4 4.4 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein TP6A_N PF04406.14 PRP84885.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SAP PF02037.27 PRP84886.1 - 0.00074 19.2 0.3 0.0014 18.4 0.3 1.4 1 0 0 1 1 1 1 SAP domain Methyltr_RsmF_N PF17125.5 PRP84886.1 - 0.097 13.2 0.0 0.38 11.3 0.0 2.0 3 0 0 3 3 3 0 N-terminal domain of 16S rRNA methyltransferase RsmF MbtH PF03621.13 PRP84887.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 MbtH-like protein XisI PF08869.11 PRP84887.1 - 0.14 12.5 0.5 1.1 9.6 0.5 2.0 1 1 0 1 1 1 0 XisI protein Phage_30_8 PF06019.11 PRP84890.1 - 0.13 12.1 0.3 6.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Phage GP30.8 protein AT_hook PF02178.19 PRP84890.1 - 0.52 10.4 4.4 1.2 9.2 4.4 1.7 1 0 0 1 1 1 0 AT hook motif WD40 PF00400.32 PRP84891.1 - 1.5e-06 28.8 1.2 0.00091 20.0 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84891.1 - 0.00021 21.5 0.0 0.23 11.8 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP84891.1 - 0.029 13.3 3.3 3.8 6.4 0.1 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PRP84891.1 - 0.15 10.6 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain PS_Dcarbxylase PF02666.15 PRP84893.1 - 1.3e-53 181.6 0.0 2e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase TusA PF01206.17 PRP84893.1 - 0.032 14.1 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 Sulfurtransferase TusA HAUS5 PF14817.6 PRP84894.1 - 4.3e-34 118.3 26.1 5.4e-20 71.7 5.2 3.0 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 5 RasGEF_N_2 PF14663.6 PRP84894.1 - 0.088 13.2 2.2 0.35 11.3 0.3 3.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MCPsignal PF00015.21 PRP84894.1 - 0.17 11.7 2.5 0.36 10.6 0.4 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1798 PF08807.10 PRP84894.1 - 0.25 11.5 0.1 0.25 11.5 0.1 3.8 4 1 0 4 4 4 0 Bacterial domain of unknown function (DUF1798) DUF2894 PF11445.8 PRP84894.1 - 4 7.9 8.0 25 5.3 0.2 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2894) UPF0020 PF01170.18 PRP84895.1 - 1.2e-28 100.2 0.3 5.5e-28 98.0 0.3 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 PRP84895.1 - 1.4e-05 24.7 0.0 1.4e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_11 PF08241.12 PRP84895.1 - 3.5e-05 24.4 0.0 0.0001 22.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP84895.1 - 0.00011 22.8 0.0 0.00025 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP84895.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PRP84895.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CDC45 PF02724.14 PRP84895.1 - 0.092 11.0 5.8 0.13 10.6 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FemAB PF02388.16 PRP84895.1 - 1.5 7.6 7.1 2.3 7.0 7.1 1.2 1 0 0 1 1 1 0 FemAB family Sec62 PF03839.16 PRP84895.1 - 3.5 7.1 9.3 7.6 6.0 9.3 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 PRP84895.1 - 5.4 6.7 5.4 12 5.6 5.4 1.5 1 0 0 1 1 1 0 Connexin Bact_lectin PF18483.1 PRP84896.1 - 6e-27 94.9 0.0 1e-26 94.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 PRP84896.1 - 1e-16 61.2 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Legume lectin domain Transglut_core PF01841.19 PRP84896.1 - 4.5e-15 56.1 0.5 1e-14 54.9 0.5 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 PRP84896.1 - 9.6e-13 48.1 0.1 2.4e-12 46.8 0.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Lectin_leg-like PF03388.13 PRP84896.1 - 3.1e-09 36.5 0.0 7.4e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Legume-like lectin family PAW PF04721.17 PRP84896.1 - 0.00014 21.7 0.2 0.00023 21.0 0.2 1.4 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Abhydrolase_3 PF07859.13 PRP84897.1 - 9e-11 42.0 0.6 1.3e-05 25.2 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP84897.1 - 4e-09 36.3 0.0 2.1e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 PRP84897.1 - 0.00042 19.3 0.0 0.00071 18.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 PRP84897.1 - 0.0019 17.7 1.1 0.93 8.9 0.5 3.0 3 0 0 3 3 3 2 Esterase PHB depolymerase Chlorophyllase PF07224.11 PRP84897.1 - 0.0094 15.0 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.18 PRP84897.1 - 0.012 15.2 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family COesterase PF00135.28 PRP84897.1 - 0.016 14.1 0.0 0.79 8.5 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_8 PF06259.12 PRP84897.1 - 0.083 12.5 0.2 0.16 11.6 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase AXE1 PF05448.12 PRP84897.1 - 0.089 11.4 0.0 2.1 7.0 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 PRP84897.1 - 0.16 11.2 0.2 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Rap_GAP PF02145.15 PRP84899.1 - 3.1e-61 206.2 0.0 8.8e-61 204.7 0.0 1.8 2 0 0 2 2 2 1 Rap/ran-GAP EF-hand_4 PF12763.7 PRP84899.1 - 8.4e-20 70.7 0.9 1.3e-08 34.7 0.1 3.0 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand PAC3 PF10178.9 PRP84899.1 - 2.8e-14 53.0 0.1 7.4e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 EF-hand_1 PF00036.32 PRP84899.1 - 1.6e-12 46.0 5.8 0.0033 16.9 0.0 5.0 4 0 0 4 4 4 4 EF hand RasGAP PF00616.19 PRP84899.1 - 2.8e-10 40.2 0.1 7.4e-09 35.6 0.1 2.7 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase EF-hand_7 PF13499.6 PRP84899.1 - 4.4e-10 39.9 3.3 0.00011 22.6 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP84899.1 - 1.1e-07 31.1 4.9 0.031 14.2 0.0 5.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 PRP84899.1 - 0.00045 19.6 7.8 0.57 9.8 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PRP84899.1 - 0.011 15.6 6.1 0.25 11.2 0.0 4.9 5 1 1 6 6 6 0 EF-hand domain pair DEK_C PF08766.11 PRP84899.1 - 0.11 12.4 0.0 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 DEK C terminal domain IBN_N PF03810.19 PRP84900.1 - 2.9e-13 49.5 0.8 1.9e-11 43.7 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 PRP84900.1 - 2.2e-08 33.0 3.8 3.1e-08 32.5 2.9 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 PRP84900.1 - 8.6e-08 31.4 0.0 1.2e-06 27.7 0.0 2.7 2 1 0 2 2 2 1 Cse1 RIX1 PF08167.12 PRP84900.1 - 0.00026 20.8 4.4 0.3 10.8 0.1 5.2 4 2 1 5 5 5 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 PRP84900.1 - 0.0013 18.8 0.0 0.0056 16.7 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.12 PRP84900.1 - 0.0018 18.4 8.1 0.0018 18.4 0.4 4.0 5 0 0 5 5 5 1 Exportin 1-like protein RTP1_C1 PF10363.9 PRP84900.1 - 0.0064 16.7 0.0 0.023 14.9 0.0 2.1 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 PRP84900.1 - 0.036 14.3 0.6 18 5.9 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 PRP84900.1 - 0.21 12.1 1.1 7.7 7.1 0.0 3.9 3 1 0 3 3 3 0 HEAT-like repeat HEAT_EZ PF13513.6 PRP84901.1 - 0.049 14.2 0.0 0.053 14.1 0.0 1.0 1 0 0 1 1 1 0 HEAT-like repeat Rdx PF10262.9 PRP84902.1 - 6.3e-11 42.3 0.0 4.1e-09 36.5 0.0 2.5 1 1 0 1 1 1 1 Rdx family SnoaL PF07366.12 PRP84902.1 - 0.18 11.6 0.0 0.57 10.0 0.0 1.7 1 1 1 2 2 2 0 SnoaL-like polyketide cyclase F-box-like PF12937.7 PRP84904.1 - 9.8e-10 38.2 1.5 1e-09 38.2 0.4 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP84904.1 - 1e-06 28.5 0.4 2e-06 27.5 0.4 1.5 1 0 0 1 1 1 1 F-box domain DUF4200 PF13863.6 PRP84904.1 - 9.4 6.7 61.1 3.5 8.0 24.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) ADIP PF11559.8 PRP84904.1 - 9.6 6.3 61.1 9.5 6.3 26.4 4.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding VHS PF00790.19 PRP84905.1 - 2.8e-06 27.2 0.0 5.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 VHS domain ubiquitin PF00240.23 PRP84906.1 - 4.4e-07 29.6 0.0 8.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF4802 PF16060.5 PRP84906.1 - 0.091 12.9 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) SPRY PF00622.28 PRP84907.1 - 2.1e-19 69.8 0.4 3.3e-19 69.2 0.4 1.3 1 0 0 1 1 1 1 SPRY domain zf-TRAF PF02176.18 PRP84907.1 - 5.4e-13 49.4 35.5 2.6e-11 44.0 9.2 4.3 3 1 1 4 4 4 3 TRAF-type zinc finger zf-RING_2 PF13639.6 PRP84907.1 - 4.7e-07 30.0 14.4 4.7e-07 30.0 14.4 3.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP84907.1 - 1.1e-06 28.4 11.6 1.1e-06 28.4 11.6 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 PRP84907.1 - 6e-05 23.1 18.8 0.00032 20.7 0.4 2.9 1 1 1 3 3 3 2 Seven in absentia protein family zf-ACC PF17848.1 PRP84907.1 - 0.00024 21.1 1.2 0.00024 21.1 1.2 4.7 5 0 0 5 5 5 2 Acetyl-coA carboxylase zinc finger domain zf-C3HC4_2 PF13923.6 PRP84907.1 - 0.00025 20.8 14.4 0.00025 20.8 14.4 3.2 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 PRP84907.1 - 0.0015 18.9 28.1 0.12 12.8 10.7 2.6 1 1 0 2 2 2 2 TRAF-like zinc-finger zf-RING_UBOX PF13445.6 PRP84907.1 - 0.013 15.5 14.6 0.013 15.5 14.6 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf_UBZ PF18439.1 PRP84907.1 - 0.51 10.0 15.7 1.5 8.5 0.4 4.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Chlam_PMP PF02415.17 PRP84908.1 - 0.0027 18.1 25.1 6.6 7.4 0.0 8.0 7 2 0 7 7 7 4 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Inhibitor_I71 PF12628.7 PRP84908.1 - 0.049 13.5 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor AAA_12 PF13087.6 PRP84909.1 - 6.7e-58 195.6 0.0 6.7e-58 195.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 PRP84909.1 - 1.3e-43 149.7 2.5 2.3e-24 86.6 0.1 5.7 2 2 1 4 4 4 2 AAA domain AAA_19 PF13245.6 PRP84909.1 - 2.7e-10 40.7 0.0 4.5e-09 36.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain Adaptin_binding PF10199.9 PRP84910.1 - 3.1e-16 60.1 0.7 5.2e-16 59.3 0.7 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 WAPL PF07814.13 PRP84912.1 - 5.6e-13 48.4 9.1 1.5e-12 47.0 9.1 1.7 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DASH_Duo1 PF08651.10 PRP84912.1 - 0.11 12.3 0.8 0.75 9.6 0.1 2.7 3 0 0 3 3 3 0 DASH complex subunit Duo1 Clathrin PF00637.20 PRP84912.1 - 0.12 12.3 2.1 5.8 6.8 0.2 3.1 3 0 0 3 3 3 0 Region in Clathrin and VPS Nic96 PF04097.14 PRP84913.1 - 2.5e-72 244.3 4.8 6.3e-70 236.3 4.8 2.5 1 1 0 1 1 1 1 Nup93/Nic96 ANAPC3 PF12895.7 PRP84913.1 - 4 7.7 6.9 2.3 8.5 0.1 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 adh_short PF00106.25 PRP84914.1 - 1.1e-22 80.5 0.0 1e-18 67.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP84914.1 - 3.9e-15 56.0 0.0 1.1e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP84914.1 - 1.3e-05 25.2 0.1 4.3e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 PRP84914.1 - 0.09 12.8 0.0 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Carn_acyltransf PF00755.20 PRP84915.1 - 1e-185 618.8 0.0 1.3e-185 618.4 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase OST-HTH PF12872.7 PRP84916.1 - 0.018 14.8 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Histone_HNS PF00816.21 PRP84916.1 - 9 7.2 16.7 4.9 8.0 0.6 3.1 2 1 1 3 3 3 0 H-NS histone family DUF2269 PF10027.9 PRP84917.1 - 0.0019 18.2 2.3 0.0026 17.8 2.3 1.2 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DUF1772 PF08592.11 PRP84917.1 - 0.0088 16.4 1.3 0.012 15.9 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) 2TM PF13239.6 PRP84917.1 - 0.25 11.7 2.6 0.5 10.7 2.6 1.5 1 0 0 1 1 1 0 2TM domain SPRY PF00622.28 PRP84918.1 - 9.5e-31 106.4 0.2 1.6e-30 105.7 0.2 1.4 1 0 0 1 1 1 1 SPRY domain Cullin_binding PF03556.15 PRP84918.1 - 3.9e-27 95.1 4.0 6.2e-27 94.4 4.0 1.3 1 0 0 1 1 1 1 Cullin binding Neuralized PF07177.12 PRP84918.1 - 0.0098 15.9 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 Neuralized Filamin PF00630.19 PRP84919.1 - 3e-26 92.2 23.1 1.2e-06 29.3 0.1 10.3 9 3 2 11 11 11 7 Filamin/ABP280 repeat Invasin_D3 PF09134.10 PRP84919.1 - 1.4e-10 41.4 20.2 0.0018 18.6 0.1 8.5 6 1 3 9 9 9 3 Invasin, domain 3 AMPK1_CBM PF16561.5 PRP84919.1 - 2.9e-09 37.0 0.2 2.9e-09 37.0 0.2 2.2 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase YtkA PF13115.6 PRP84919.1 - 7e-08 33.0 17.5 3.5 8.3 0.0 9.1 9 1 0 9 9 9 3 YtkA-like DUF3471 PF11954.8 PRP84919.1 - 0.042 14.3 1.0 37 4.9 0.3 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF3471) MG2 PF01835.19 PRP84919.1 - 0.05 14.0 0.7 33 5.0 0.0 5.0 5 1 1 6 6 6 0 MG2 domain He_PIG PF05345.12 PRP84919.1 - 6.9 7.0 6.5 10 6.4 0.1 3.6 3 0 0 3 3 3 0 Putative Ig domain HhH-GPD PF00730.25 PRP84922.1 - 1.1e-19 70.8 0.0 2.4e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 PRP84922.1 - 2.7e-16 59.5 0.0 8e-16 58.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain HHH PF00633.23 PRP84922.1 - 8.4e-09 34.9 0.2 2.2e-08 33.5 0.2 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 PRP84922.1 - 0.00031 21.0 7.1 0.00056 20.2 7.1 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III Gly_transf_sug PF04488.15 PRP84922.1 - 0.00051 20.6 0.1 0.0017 19.0 0.1 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RF-1 PF00472.20 PRP84923.1 - 1.7e-18 66.6 1.3 2.5e-18 66.1 1.3 1.2 1 0 0 1 1 1 1 RF-1 domain DUF1335 PF07056.11 PRP84923.1 - 0.18 11.9 0.0 2.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) Pkinase PF00069.25 PRP84924.1 - 5.6e-56 189.8 0.0 1.7e-55 188.2 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84924.1 - 6.8e-41 140.2 0.0 1.2e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP84924.1 - 0.00081 19.4 0.0 0.0019 18.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP84924.1 - 0.0024 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP84924.1 - 0.0058 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CCG PF02754.16 PRP84924.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Cysteine-rich domain FTA2 PF13095.6 PRP84924.1 - 0.13 11.9 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 X8 PF07983.13 PRP84925.1 - 5.2e-37 126.4 16.2 9.4e-13 48.7 0.9 3.8 3 1 0 3 3 3 3 X8 domain Amino_oxidase PF01593.24 PRP84925.1 - 1.2e-12 47.9 0.0 1.1e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP84925.1 - 1.3e-11 44.6 0.0 2.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PRP84925.1 - 0.0012 18.9 0.0 0.0025 17.8 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 PRP84925.1 - 0.0078 15.8 0.0 0.22 11.0 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase SNF2_N PF00176.23 PRP84926.1 - 1.8e-87 293.3 0.2 3.2e-87 292.5 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Guanylate_cyc PF00211.20 PRP84926.1 - 1.6e-64 216.9 1.5 3.7e-31 108.2 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain dCache_1 PF02743.18 PRP84926.1 - 5.6e-12 46.0 5.2 1.4e-05 25.0 0.6 2.8 2 0 0 2 2 2 2 Cache domain zf-C3HC4 PF00097.25 PRP84926.1 - 1.3e-07 31.3 7.8 1.3e-07 31.3 7.8 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP84926.1 - 1.9e-07 31.3 8.9 1.9e-07 31.3 8.9 3.2 3 0 0 3 3 1 1 Ring finger domain Helicase_C PF00271.31 PRP84926.1 - 1.3e-06 28.7 0.0 6e-06 26.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 PRP84926.1 - 2.6e-06 27.3 12.0 3.3e-06 27.0 8.7 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP84926.1 - 7.8e-06 25.7 7.3 7.8e-06 25.7 7.3 2.7 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP84926.1 - 1.2e-05 25.2 7.7 1.2e-05 25.2 7.7 3.1 3 0 0 3 3 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PRP84926.1 - 6.3e-05 23.0 11.3 0.0023 18.1 7.7 3.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Phage_holin_7_1 PF16081.5 PRP84926.1 - 0.00036 20.7 6.5 0.14 12.3 1.1 2.5 2 0 0 2 2 2 2 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family zf-C3HC4_2 PF13923.6 PRP84926.1 - 0.00057 19.7 13.4 0.00062 19.6 8.8 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 PRP84926.1 - 0.0037 17.1 13.5 0.0037 17.1 13.5 3.0 3 0 0 3 3 2 1 PHD-finger zf-RING_4 PF14570.6 PRP84926.1 - 0.0062 16.3 5.6 0.02 14.7 5.6 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain TPR_1 PF00515.28 PRP84926.1 - 0.024 14.4 0.0 0.071 13.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP84926.1 - 0.035 13.8 0.0 0.15 11.8 0.0 2.0 1 0 0 1 1 1 0 TPR repeat zf-RING_11 PF17123.5 PRP84926.1 - 0.068 12.9 4.3 0.26 11.1 4.3 2.1 1 0 0 1 1 1 0 RING-like zinc finger TPR_12 PF13424.6 PRP84926.1 - 0.083 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4736 PF15883.5 PRP84926.1 - 0.096 12.4 1.1 14 5.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) Prok-RING_4 PF14447.6 PRP84926.1 - 0.76 9.7 9.9 6.2 6.8 10.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF2157 PF09925.9 PRP84926.1 - 0.9 9.3 5.4 14 5.5 0.3 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) EZH2_WD-Binding PF11616.8 PRP84926.1 - 3.9 7.7 9.1 9 6.5 0.3 2.9 3 0 0 3 3 2 0 WD repeat binding protein EZH2 Glyco_hydro_61 PF03443.14 PRP84927.1 - 6.3e-14 52.4 0.0 9.4e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 PRP84927.1 - 1.8e-07 32.1 0.6 1.1e-06 29.5 0.3 2.1 1 1 1 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_19 PF03427.13 PRP84927.1 - 4.2 7.4 10.0 1.7 8.7 5.4 2.5 3 0 0 3 3 3 0 Carbohydrate binding domain (family 19) Abhydrolase_1 PF00561.20 PRP84928.1 - 4.6e-07 29.7 0.2 2.7e-06 27.2 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP84928.1 - 2.9e-05 24.8 0.6 7.5e-05 23.4 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP84928.1 - 4e-05 23.0 0.0 0.00078 18.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 PRP84928.1 - 0.0013 18.5 0.2 0.0027 17.5 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 PRP84928.1 - 0.0083 16.0 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Ndr PF03096.14 PRP84928.1 - 0.061 12.0 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF676 PF05057.14 PRP84928.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 PRP84928.1 - 0.17 11.4 0.1 0.42 10.1 0.1 1.6 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 PRP84929.1 - 2.1e-21 76.8 0.1 3.8e-21 75.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 PRP84929.1 - 3.1e-17 61.9 0.0 7.5e-17 60.7 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 PRP84929.1 - 1.5e-05 24.4 0.0 0.00022 20.5 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP84929.1 - 0.0029 18.2 0.0 0.0051 17.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 PRP84929.1 - 0.076 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase RasGEF PF00617.19 PRP84930.1 - 5.9e-39 134.1 0.0 4.9e-38 131.1 0.0 2.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 PRP84930.1 - 8.3e-14 51.7 0.2 2.2e-13 50.3 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif GRAM PF02893.20 PRP84931.1 - 0.00016 21.5 0.2 0.0014 18.5 0.2 2.1 1 1 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.6 PRP84931.1 - 0.011 15.1 3.2 2 8.1 0.3 2.3 2 0 0 2 2 2 0 EF hand Dockerin_1 PF00404.18 PRP84931.1 - 0.098 12.9 2.8 8.2 6.7 2.7 2.5 1 1 0 1 1 1 0 Dockerin type I domain Metallophos PF00149.28 PRP84932.1 - 1.6e-13 51.6 1.8 3e-13 50.7 1.8 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BLOC1_2 PF10046.9 PRP84933.1 - 3.1e-28 97.9 5.6 3.7e-28 97.7 5.6 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 PRP84933.1 - 0.00045 20.4 0.2 0.00097 19.4 0.2 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Secretogranin_V PF05281.11 PRP84933.1 - 0.012 15.2 0.2 0.014 15.0 0.2 1.2 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) DUF1664 PF07889.12 PRP84933.1 - 0.016 15.3 0.5 0.022 14.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sipho_Gp157 PF05565.11 PRP84933.1 - 0.016 15.2 5.7 0.084 12.9 1.1 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 Rootletin PF15035.6 PRP84933.1 - 0.021 14.9 3.2 0.035 14.1 3.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-R PF06729.12 PRP84933.1 - 0.042 13.8 1.5 0.053 13.4 1.5 1.2 1 0 0 1 1 1 0 Kinetochore component, CENP-R Fib_alpha PF08702.10 PRP84933.1 - 0.049 13.8 1.9 0.41 10.8 1.4 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 PRP84933.1 - 0.052 14.0 3.3 0.067 13.7 3.3 1.1 1 0 0 1 1 1 0 Spectrin repeat Exonuc_VII_L PF02601.15 PRP84933.1 - 0.15 11.6 1.5 0.17 11.4 1.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit WD40 PF00400.32 PRP84934.1 - 0.00027 21.7 0.6 11 7.0 0.0 5.1 4 1 0 4 4 4 2 WD domain, G-beta repeat Mpv17_PMP22 PF04117.12 PRP84936.1 - 3.3e-23 81.7 1.1 5.8e-23 80.9 1.1 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family C1_2 PF03107.16 PRP84937.1 - 1.1 9.7 3.2 43 4.5 0.1 3.0 3 0 0 3 3 3 0 C1 domain Lactonase PF10282.9 PRP84940.1 - 6.7e-83 278.8 0.0 8.8e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Carb_bind PF10645.9 PRP84940.1 - 2.7e-05 24.3 12.1 2.7e-05 24.3 12.1 2.9 1 1 1 2 2 2 2 Carbohydrate binding SGL PF08450.12 PRP84940.1 - 6.5e-05 22.6 0.3 0.026 14.1 0.0 2.6 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Phytase PF02333.15 PRP84940.1 - 0.17 10.8 0.4 8.9 5.2 0.1 2.5 2 0 0 2 2 2 0 Phytase DDE_Tnp_4 PF13359.6 PRP84941.1 - 0.0002 21.1 0.0 0.01 15.5 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease Sulfate_transp PF00916.20 PRP84942.1 - 5.5e-67 226.2 16.7 8.7e-67 225.5 16.7 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PRP84942.1 - 1e-12 47.7 0.0 1.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain TMEM220 PF15071.6 PRP84942.1 - 0.12 13.2 0.8 3 8.7 0.0 2.9 2 0 0 2 2 2 0 Transmembrane family 220, helix MFS_MOT1 PF16983.5 PRP84942.1 - 1.1 9.6 15.8 0.033 14.6 4.3 3.2 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF3995 PF13160.6 PRP84942.1 - 8.8 6.7 7.9 7.2 7.0 0.8 3.6 2 2 1 3 3 3 0 Protein of unknown function (DUF3995) DUF3429 PF11911.8 PRP84943.1 - 3.6e-32 111.6 7.7 4.4e-32 111.3 7.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF5360 PF17314.2 PRP84943.1 - 0.062 13.4 0.6 0.094 12.8 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5360) HsbA PF12296.8 PRP84944.1 - 1e-14 55.0 2.7 1.7e-14 54.3 2.7 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A WRNPLPNID PF15017.6 PRP84944.1 - 0.027 15.3 0.2 0.053 14.4 0.2 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Methyltransf_11 PF08241.12 PRP84945.1 - 8.1e-22 77.7 0.0 1.8e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP84945.1 - 7.5e-20 71.5 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP84945.1 - 6.8e-14 51.9 0.0 1.3e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP84945.1 - 1.4e-11 45.0 0.0 2.6e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP84945.1 - 9.1e-11 41.9 0.0 1.5e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP84945.1 - 5.7e-10 38.9 0.0 9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 PRP84945.1 - 0.00074 18.7 0.0 0.0019 17.3 0.0 1.6 2 0 0 2 2 2 1 DREV methyltransferase MTS PF05175.14 PRP84945.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 PRP84945.1 - 0.0035 17.2 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 PRP84945.1 - 0.0046 16.3 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 PRP84945.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 PRP84945.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 PRP84945.1 - 0.032 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 PRP84945.1 - 0.079 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 PRP84945.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_15 PF09445.10 PRP84945.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HEAT PF02985.22 PRP84949.1 - 5.4e-52 169.3 29.6 0.012 15.8 0.1 25.2 26 0 0 26 26 25 13 HEAT repeat HEAT_EZ PF13513.6 PRP84949.1 - 2.9e-38 129.8 31.4 1.3e-05 25.6 0.1 21.2 18 4 5 23 23 23 6 HEAT-like repeat HEAT_2 PF13646.6 PRP84949.1 - 1.5e-37 127.8 28.1 2.7e-06 27.7 0.0 17.4 13 4 5 19 19 17 9 HEAT repeats Cnd1 PF12717.7 PRP84949.1 - 8.6e-16 58.4 22.3 0.15 12.1 0.1 12.4 9 3 2 12 12 12 5 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PRP84949.1 - 2.6e-14 53.6 5.0 0.17 12.5 0.0 11.3 11 2 1 12 12 11 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 PRP84949.1 - 9.1e-13 48.3 10.3 0.081 12.5 0.0 10.0 9 2 2 11 11 11 3 CLASP N terminal UME PF08064.13 PRP84949.1 - 2.8e-07 30.4 5.8 0.091 12.7 0.6 8.5 8 2 1 9 9 9 1 UME (NUC010) domain DUF3385 PF11865.8 PRP84949.1 - 7.6e-05 22.7 14.7 0.23 11.4 0.0 8.4 8 1 0 9 9 9 2 Domain of unknown function (DUF3385) TIP120 PF08623.10 PRP84949.1 - 8.8e-05 22.3 3.9 0.0093 15.8 0.0 5.7 5 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) ParcG PF10274.9 PRP84949.1 - 0.00021 21.5 17.5 0.2 11.8 0.4 8.8 9 1 1 10 10 9 1 Parkin co-regulated protein RPA PF10134.9 PRP84949.1 - 0.021 14.3 0.6 0.12 11.9 0.6 2.2 2 0 0 2 2 2 0 Replication initiator protein A RIX1 PF08167.12 PRP84949.1 - 0.03 14.0 0.1 0.03 14.0 0.1 8.0 10 0 0 10 10 10 0 rRNA processing/ribosome biogenesis NUC173 PF08161.12 PRP84949.1 - 0.057 13.1 3.1 3.8 7.1 0.0 5.0 5 0 0 5 5 5 0 NUC173 domain ArAE_1_C PF11728.8 PRP84949.1 - 0.089 12.8 0.4 0.62 10.0 0.4 2.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain DUF1722 PF08349.11 PRP84949.1 - 0.13 12.5 1.5 2.1 8.7 0.2 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Phage_Treg PF04761.12 PRP84949.1 - 0.17 12.0 0.1 0.82 9.8 0.1 2.2 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Proteasom_PSMB PF10508.9 PRP84949.1 - 2.1 6.8 21.8 0.04 12.4 2.1 5.9 6 1 1 7 7 7 0 Proteasome non-ATPase 26S subunit Paramyxo_P PF01806.17 PRP84951.1 - 0.11 11.9 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region RasGEF PF00617.19 PRP84952.1 - 4.2e-34 118.3 0.0 7.8e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Peptidase_M22 PF00814.25 PRP84954.1 - 7.6e-91 304.6 0.0 1.1e-90 304.1 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 PRP84954.1 - 0.046 13.4 0.1 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus CNDH2_C PF16858.5 PRP84955.1 - 3.6e-48 165.0 0.0 3.6e-48 165.0 0.0 3.1 2 1 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 PRP84955.1 - 7.2e-27 93.8 0.1 7.2e-27 93.8 0.1 3.4 4 1 0 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal RR_TM4-6 PF06459.12 PRP84955.1 - 0.39 10.5 19.0 0.72 9.6 10.2 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 PRP84955.1 - 6.8 5.4 14.1 3.1 6.5 1.9 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MORN PF02493.20 PRP84956.1 - 1.6e-53 175.5 71.0 4.8e-07 29.3 0.8 10.5 10 0 0 10 10 10 10 MORN repeat DUF2158 PF09926.9 PRP84956.1 - 0.06 13.1 0.6 15 5.4 0.0 3.4 2 1 0 2 2 2 0 Uncharacterized small protein (DUF2158) DUF3048_C PF17479.2 PRP84956.1 - 4.2 7.8 10.2 3.7 8.0 0.1 3.6 2 1 1 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain tRNA-synt_2 PF00152.20 PRP84957.1 - 1e-98 330.3 0.0 1.2e-98 330.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 PRP84957.1 - 1.9e-10 40.9 0.1 5.8e-10 39.3 0.1 1.9 2 0 0 2 2 2 1 GAD domain tRNA_anti-codon PF01336.25 PRP84957.1 - 2.8e-09 36.8 0.0 6.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PRP84957.1 - 0.017 14.6 0.1 0.096 12.1 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 PRP84957.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_S17_N PF16205.5 PRP84958.1 - 2.7e-29 101.3 0.6 5.3e-29 100.4 0.6 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 PRP84958.1 - 3.1e-24 84.8 0.1 4.8e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 RasGEF PF00617.19 PRP84959.1 - 9.5e-32 110.6 0.0 2.2e-31 109.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain PP-binding PF00550.25 PRP84959.1 - 3e-09 37.1 0.0 5.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site RasGEF_N PF00618.20 PRP84959.1 - 4.9e-06 26.7 0.8 1.8e-05 24.9 0.3 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif PP-binding_2 PF14573.6 PRP84959.1 - 0.045 14.0 0.2 0.16 12.2 0.2 1.9 1 0 0 1 1 1 0 Acyl-carrier Colicin PF01024.19 PRP84960.1 - 0.014 15.3 0.7 0.029 14.3 0.6 1.4 1 1 0 1 1 1 0 Colicin pore forming domain DIT1_PvcA PF05141.12 PRP84960.1 - 0.1 12.1 2.7 0.14 11.6 2.7 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Pkinase_Tyr PF07714.17 PRP84961.1 - 2.4e-76 256.5 0.0 3.3e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP84961.1 - 5.3e-53 180.1 0.0 7.8e-53 179.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP84961.1 - 3.1e-30 103.7 99.3 2.1e-08 33.8 2.5 15.4 13 4 2 16 16 16 8 Leucine rich repeat LRR_4 PF12799.7 PRP84961.1 - 2.2e-21 75.6 103.4 5e-06 26.8 0.2 17.7 8 3 13 21 21 21 13 Leucine Rich repeats (2 copies) Kdo PF06293.14 PRP84961.1 - 4.1e-05 23.0 0.1 8.6e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 PRP84961.1 - 0.00029 20.4 12.9 0.016 14.7 0.3 5.7 5 1 1 6 6 6 1 Leucine-rich repeat Pkinase_fungal PF17667.1 PRP84961.1 - 0.036 12.8 0.1 0.053 12.3 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Neurensin PF14927.6 PRP84961.1 - 0.043 13.5 0.2 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 Neurensin Amnionless PF14828.6 PRP84961.1 - 0.067 12.0 0.3 0.12 11.2 0.3 1.3 1 0 0 1 1 1 0 Amnionless TFIID-31kDa PF02291.15 PRP84961.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LRR_6 PF13516.6 PRP84961.1 - 0.11 12.7 85.1 7.3 6.9 0.3 23.3 28 0 0 28 28 27 0 Leucine Rich repeat LRR_2 PF07723.13 PRP84961.1 - 1.4 9.7 9.1 6.5 7.6 0.1 6.1 5 1 1 6 6 5 0 Leucine Rich Repeat LRR_1 PF00560.33 PRP84961.1 - 8.7 7.3 82.0 2.8 8.8 0.0 21.5 26 2 0 26 26 22 0 Leucine Rich Repeat Colipase-like PF15083.6 PRP84963.1 - 0.064 13.4 12.4 0.8 9.9 4.6 2.2 2 0 0 2 2 2 0 Colipase-like AA_permease PF00324.21 PRP84964.1 - 8.6e-128 426.9 40.2 1e-127 426.7 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 PRP84964.1 - 9.5e-30 103.8 43.8 1.3e-29 103.4 43.8 1.2 1 0 0 1 1 1 1 Amino acid permease YpmT PF17431.2 PRP84964.1 - 0.014 15.4 0.9 0.053 13.6 0.9 2.0 1 0 0 1 1 1 0 Uncharacterized YmpT-like ALMT PF11744.8 PRP84965.1 - 7.6 5.2 8.5 3.7 6.3 6.4 1.4 1 1 1 2 2 2 0 Aluminium activated malate transporter Ank_2 PF12796.7 PRP84966.1 - 2.7e-06 27.9 0.0 0.26 11.9 0.1 3.8 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84966.1 - 7.6e-06 26.4 6.4 0.11 13.1 0.2 5.7 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP84966.1 - 1.8e-05 24.9 0.2 4.5 7.7 0.0 5.8 6 1 0 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84966.1 - 4.3e-05 23.6 0.8 62 4.7 0.0 6.9 7 0 0 7 7 7 0 Ankyrin repeat PPR_2 PF13041.6 PRP84966.1 - 0.0058 16.8 0.1 0.35 11.1 0.0 2.9 3 0 0 3 3 3 1 PPR repeat family AalphaY_MDB PF04611.12 PRP84966.1 - 0.14 12.2 0.7 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region TPR_MLP1_2 PF07926.12 PRP84966.1 - 0.28 11.3 43.2 0.85 9.7 9.0 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 PRP84966.1 - 0.29 10.5 24.0 0.1 11.9 13.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 PRP84966.1 - 0.84 10.4 29.7 3.3 8.5 2.9 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) Glu-tRNAGln PF02686.15 PRP84966.1 - 2.2 8.6 4.7 6.1 7.2 0.1 3.4 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Fez1 PF06818.15 PRP84966.1 - 7.3 7.0 34.3 0.048 14.1 16.7 2.4 1 1 1 2 2 2 0 Fez1 DCP1 PF06058.13 PRP84967.1 - 1.8e-40 137.5 0.5 3.7e-40 136.5 0.0 1.7 2 0 0 2 2 2 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 PRP84967.1 - 4.2e-05 22.7 0.0 8.3e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus TFIIA PF03153.13 PRP84967.1 - 0.025 14.6 26.2 0.034 14.2 26.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MBD PF01429.19 PRP84967.1 - 0.098 12.4 0.4 0.28 10.9 0.4 1.8 1 0 0 1 1 1 0 Methyl-CpG binding domain EB1 PF03271.17 PRP84968.1 - 3.5e-15 56.0 1.8 7.5e-15 54.9 1.8 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 PRP84968.1 - 2.6e-08 34.0 2.4 9.6e-08 32.2 1.5 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 PRP84968.1 - 0.0076 16.4 2.3 0.014 15.5 1.3 2.0 2 1 1 3 3 3 1 CH-like domain in sperm protein Suppressor_APC PF11414.8 PRP84968.1 - 0.012 15.6 0.1 0.025 14.6 0.1 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein ASFV_J13L PF05568.11 PRP84968.1 - 0.11 12.3 8.7 0.025 14.4 5.5 1.5 2 0 0 2 2 2 0 African swine fever virus J13L protein DUF4522 PF15022.6 PRP84968.1 - 0.25 11.6 1.4 3 8.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) FlxA PF14282.6 PRP84968.1 - 0.27 11.3 2.0 0.55 10.3 1.9 1.6 1 1 0 1 1 1 0 FlxA-like protein Ank_2 PF12796.7 PRP84969.1 - 4.2e-13 49.7 1.5 1.6e-05 25.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP84969.1 - 2.6e-08 34.2 1.4 1.8e-06 28.3 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP84969.1 - 3e-07 30.2 0.8 0.09 13.4 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 PRP84969.1 - 4.5e-05 23.7 3.5 6.1 7.5 0.1 4.8 2 1 2 4 4 4 3 Ankyrin repeat MtN3_slv PF03083.16 PRP84970.1 - 6.8e-29 99.7 15.6 6.2e-18 64.6 2.8 2.7 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange HATPase_c PF02518.26 PRP84970.1 - 3.8e-25 88.6 0.9 8.7e-25 87.4 0.3 1.9 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP84970.1 - 1.4e-24 86.4 0.0 3.3e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.6 PRP84970.1 - 3e-22 79.8 0.0 1.3e-21 77.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP84970.1 - 2.5e-16 59.8 0.0 5.6e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84970.1 - 9.1e-11 41.5 0.0 2.5e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase HisKA PF00512.25 PRP84970.1 - 3.6e-08 33.3 0.3 1.3e-07 31.5 0.3 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_22 PF13401.6 PRP84970.1 - 0.0015 18.8 0.2 0.019 15.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain GAF_2 PF13185.6 PRP84970.1 - 0.0045 17.3 0.0 0.62 10.4 0.0 2.8 1 1 0 1 1 1 1 GAF domain RsgA_GTPase PF03193.16 PRP84970.1 - 0.0064 16.4 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase DUF815 PF05673.13 PRP84970.1 - 0.014 14.6 0.0 0.042 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 PRP84970.1 - 0.016 14.8 0.1 0.063 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP84970.1 - 0.05 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain HATPase_c_3 PF13589.6 PRP84970.1 - 0.067 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 PRP84970.1 - 0.069 13.8 0.0 0.22 12.2 0.0 2.0 1 0 0 1 1 1 0 GAF domain Sigma54_activat PF00158.26 PRP84970.1 - 0.079 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 PRP84970.1 - 0.11 12.1 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 PRP84970.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF116 PF01976.17 PRP84970.1 - 0.11 12.0 0.3 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF116 NACHT PF05729.12 PRP84970.1 - 0.56 10.1 5.9 1.8 8.5 5.9 1.9 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 PRP84970.1 - 1.2 9.7 3.9 4.4 7.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain PhoLip_ATPase_C PF16212.5 PRP84971.1 - 6e-71 239.1 20.1 6e-71 239.1 20.1 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP84971.1 - 9.1e-15 54.1 17.2 2.7e-13 49.4 2.6 3.1 3 0 0 3 3 3 2 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PRP84971.1 - 4.4e-11 43.5 1.5 0.00011 22.5 0.2 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PRP84971.1 - 4.3e-10 39.4 0.3 5.3e-09 35.9 0.0 3.0 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 PRP84971.1 - 5.9e-07 29.5 0.0 2.1e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP84971.1 - 6.3e-05 22.8 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LSM PF01423.22 PRP84972.1 - 4.3e-18 64.8 0.7 6.2e-18 64.2 0.1 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 PRP84972.1 - 0.00014 21.9 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Spore_YhaL PF14147.6 PRP84972.1 - 0.034 13.8 0.1 0.056 13.1 0.1 1.2 1 0 0 1 1 1 0 Sporulation protein YhaL RRM_1 PF00076.22 PRP84973.1 - 5.3e-31 106.3 0.3 7.4e-19 67.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PRP84973.1 - 0.0053 16.6 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 PRP84973.1 - 0.1 12.2 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 PRP84974.1 - 5.7e-64 209.5 16.3 4.1e-08 32.7 0.1 10.3 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.17 PRP84974.1 - 1.5e-54 177.8 17.1 2.5e-06 27.2 0.0 10.3 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_8 PF13181.6 PRP84974.1 - 9.8e-43 140.8 15.6 4.9e-06 26.3 0.0 10.4 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 PRP84974.1 - 4e-32 108.3 15.8 0.0016 18.7 0.1 10.9 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 PRP84974.1 - 1.6e-29 102.0 16.5 1.4e-07 31.6 0.1 7.6 5 3 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 PRP84974.1 - 2.7e-29 99.3 6.6 0.0061 17.3 0.0 9.9 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 PRP84974.1 - 4.1e-29 100.9 6.3 7.1e-05 23.2 0.3 6.6 4 1 1 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 PRP84974.1 - 7.4e-28 96.9 4.4 9.4e-07 29.4 0.0 6.3 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 PRP84974.1 - 7.7e-25 85.1 12.2 0.064 13.3 0.3 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_6 PF13174.6 PRP84974.1 - 1.6e-21 75.4 13.9 0.0022 18.5 0.0 9.7 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 PRP84974.1 - 3.2e-17 61.9 31.9 5.6e-06 25.9 1.7 10.2 2 2 8 10 10 10 5 TPR repeat TPR_9 PF13371.6 PRP84974.1 - 8.5e-16 57.9 8.7 0.0018 18.4 0.5 5.9 1 1 4 6 6 6 5 Tetratricopeptide repeat TPR_15 PF13429.6 PRP84974.1 - 1.8e-11 43.8 9.0 6.9e-06 25.5 4.7 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP84974.1 - 3.7e-11 43.1 14.4 1e-05 25.6 1.0 4.3 2 1 4 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 PRP84974.1 - 7.5e-10 38.8 3.9 0.0007 19.4 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 PRP84974.1 - 6.7e-06 26.4 2.8 1.8 8.9 0.0 6.7 4 2 4 8 8 7 1 Tetratricopeptide repeat Tcf25 PF04910.14 PRP84974.1 - 8.2e-05 21.8 0.9 0.029 13.4 0.1 2.6 2 0 0 2 2 2 2 Transcriptional repressor TCF25 DUF2225 PF09986.9 PRP84974.1 - 0.00022 21.0 0.8 1.4 8.6 0.1 4.0 1 1 3 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.17 PRP84974.1 - 0.0031 18.0 9.6 1.1 9.7 0.1 4.1 4 0 0 4 4 4 1 Bacterial transcriptional activator domain ChAPs PF09295.10 PRP84974.1 - 0.018 14.0 6.4 0.063 12.3 0.0 3.5 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3808 PF10300.9 PRP84974.1 - 0.045 12.5 0.3 0.12 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) Rapsyn_N PF10579.9 PRP84974.1 - 0.092 12.9 0.1 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region DUF410 PF04190.13 PRP84974.1 - 1.1 8.9 4.9 10 5.8 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF410) MIT PF04212.18 PRP84974.1 - 1.8 8.7 13.2 77 3.5 1.7 5.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 PRP84974.1 - 1.9 8.4 22.7 26 4.9 0.2 8.0 10 0 0 10 10 8 0 Tetratricopeptide repeat eIF2A PF08662.11 PRP84975.1 - 5.7e-54 182.9 1.3 1.2e-48 165.6 0.3 3.4 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 PRP84975.1 - 4.7e-09 36.0 0.1 1.5e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 PRP84975.1 - 0.0077 14.3 0.1 0.017 13.1 0.1 1.6 1 1 0 1 1 1 1 IKI3 family DUF502 PF04367.13 PRP84975.1 - 0.0083 16.0 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF502) TFIIIC_delta PF12657.7 PRP84975.1 - 0.68 9.8 3.7 6.2 6.7 0.1 3.3 3 2 0 3 3 3 0 Transcription factor IIIC subunit delta N-term CLU PF13236.6 PRP84978.1 - 2.9e-50 171.2 0.0 9.3e-50 169.5 0.0 1.9 1 0 0 1 1 1 1 Clustered mitochondria RhoGAP PF00620.27 PRP84978.1 - 6.4e-38 130.0 0.1 2e-37 128.3 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.25 PRP84978.1 - 8.4e-26 90.9 0.4 1.7e-25 89.9 0.4 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP84978.1 - 4.4e-23 81.9 0.2 1.5e-22 80.2 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase SH3_1 PF00018.28 PRP84978.1 - 3.4e-10 39.4 0.0 7.8e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP84978.1 - 1.2e-09 37.7 3.8 7.2e-09 35.2 0.0 3.4 3 1 0 3 3 3 1 Variant SH3 domain GPS PF01825.21 PRP84978.1 - 2.5e-08 34.3 7.0 7.6e-08 32.8 7.0 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif SH3_9 PF14604.6 PRP84978.1 - 2.4e-07 30.5 0.0 5.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain eIF3_p135 PF12807.7 PRP84978.1 - 8.6e-05 22.6 0.2 0.00036 20.6 0.2 2.0 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 PQQ_2 PF13360.6 PRP84978.1 - 0.0022 17.6 0.3 0.0048 16.5 0.3 1.5 1 0 0 1 1 1 1 PQQ-like domain B_lectin PF01453.24 PRP84978.1 - 0.0042 17.6 3.0 0.04 14.5 2.5 2.5 1 1 1 2 2 2 2 D-mannose binding lectin CLU PF13236.6 PRP84979.1 - 1.2e-50 172.4 0.0 3e-50 171.1 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP84979.1 - 1.7e-07 31.4 0.2 3.9e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 5_nucleotid PF05761.14 PRP84980.1 - 1.2e-118 397.0 2.7 1.3e-118 396.8 2.7 1.0 1 0 0 1 1 1 1 5' nucleotidase family Hydrolase PF00702.26 PRP84980.1 - 0.0077 16.5 0.0 0.066 13.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AMP_N PF05195.16 PRP84980.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain LpxB PF02684.15 PRP84980.1 - 0.12 11.2 0.0 0.62 8.8 0.0 2.0 2 0 0 2 2 2 0 Lipid-A-disaccharide synthetase CLU PF13236.6 PRP84981.1 - 6.7e-50 170.0 0.0 2e-49 168.4 0.0 1.8 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP84981.1 - 8.6e-09 35.7 0.7 2.6e-08 34.1 0.7 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Elongin_A PF06881.11 PRP84981.1 - 0.06 13.9 1.4 1.2 9.7 0.1 3.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Homeodomain PF00046.29 PRP84982.1 - 1.3e-13 50.5 2.2 3e-13 49.4 2.2 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP84982.1 - 1.2e-05 25.1 2.9 1.5e-05 24.8 1.4 2.0 2 0 0 2 2 2 1 Homeobox KN domain Ank_2 PF12796.7 PRP84983.1 - 9.3e-05 22.9 0.1 0.18 12.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP84983.1 - 0.00048 20.4 0.0 11 6.9 0.0 4.7 3 0 0 3 3 3 2 Ankyrin repeat HECT PF00632.25 PRP84984.1 - 2.2e-50 171.9 0.0 4.9e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 PRP84984.1 - 8.2e-17 61.4 0.5 2e-16 60.2 0.5 1.7 1 0 0 1 1 1 1 SPRY domain UBA PF00627.31 PRP84984.1 - 0.00022 21.1 0.2 0.00073 19.4 0.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.22 PRP84984.1 - 0.0058 16.4 0.0 0.021 14.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EST1 PF10374.9 PRP84984.1 - 0.9 10.2 4.5 23 5.6 0.0 4.3 5 0 0 5 5 5 0 Telomerase activating protein Est1 UIM PF02809.20 PRP84984.1 - 5.8 7.1 13.8 0.55 10.3 1.1 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif ABC_membrane PF00664.23 PRP84985.1 - 4.2e-111 371.0 28.1 6.2e-59 199.9 10.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP84985.1 - 3e-70 235.1 0.0 1e-34 120.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PRP84985.1 - 9.4e-18 64.4 0.0 3.7e-08 33.1 0.0 3.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RasGAP PF00616.19 PRP84985.1 - 9.5e-10 38.5 0.0 1.7e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase AAA_16 PF13191.6 PRP84985.1 - 1.1e-08 35.7 2.7 0.0011 19.3 0.1 3.4 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 PRP84985.1 - 4e-08 32.5 0.5 0.0026 16.6 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 PRP84985.1 - 5.4e-08 33.2 1.1 0.0035 17.6 0.2 3.8 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 PRP84985.1 - 9.3e-06 25.5 0.5 0.018 14.8 0.1 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PRP84985.1 - 5.9e-05 23.0 0.5 0.28 11.1 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 PRP84985.1 - 8e-05 22.3 1.4 0.11 12.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 PRP84985.1 - 0.00031 20.9 4.3 0.31 11.3 0.3 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.29 PRP84985.1 - 0.001 19.5 3.4 4 7.9 0.0 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 PRP84985.1 - 0.0011 18.3 0.5 2.6 7.3 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin Rad17 PF03215.15 PRP84985.1 - 0.0025 17.8 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 PRP84985.1 - 0.0026 17.5 0.0 2.9 7.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 PRP84985.1 - 0.0098 16.1 0.0 2.8 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PRP84985.1 - 0.011 15.4 0.0 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PRP84985.1 - 0.016 14.7 0.0 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 PRP84985.1 - 0.016 15.2 0.2 5.1 7.1 0.0 3.7 4 1 0 4 4 3 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 PRP84985.1 - 0.017 14.9 0.1 0.49 10.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase START PF01852.19 PRP84985.1 - 0.018 14.5 0.1 0.042 13.3 0.1 1.5 1 0 0 1 1 1 0 START domain G-alpha PF00503.20 PRP84985.1 - 0.062 12.5 0.0 7 5.7 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.6 PRP84985.1 - 0.1 12.8 0.3 11 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PRP84985.1 - 0.18 12.2 0.1 23 5.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 PRP84985.1 - 1.6 8.4 3.6 31 4.2 0.1 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Sugar_tr PF00083.24 PRP84986.1 - 4.8e-49 167.5 23.9 1.8e-46 158.9 23.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP84986.1 - 1.9e-23 83.0 45.7 8.9e-23 80.8 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PRP84986.1 - 1.8e-06 27.5 1.3 4.1e-06 26.3 1.3 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 PRP84986.1 - 5.2 6.7 5.4 33 4.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) PNP_phzG_C PF10590.9 PRP84987.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.5 1 1 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region adh_short PF00106.25 PRP84988.1 - 7.4e-40 136.5 2.4 1.6e-33 115.8 0.5 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP84988.1 - 1.6e-33 116.2 1.1 2.2e-29 102.7 0.7 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP84988.1 - 8.7e-15 55.1 0.7 1.4e-14 54.4 0.7 1.3 1 0 0 1 1 1 1 KR domain Metallophos_3 PF14582.6 PRP84989.1 - 0.02 14.3 0.1 0.028 13.8 0.1 1.1 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily DUF3770 PF12603.8 PRP84989.1 - 0.021 14.3 0.5 0.037 13.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) DUF2959 PF11172.8 PRP84989.1 - 0.094 12.8 10.1 0.14 12.3 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) RNF220 PF15926.5 PRP84989.1 - 0.1 12.2 2.3 0.2 11.2 2.3 1.6 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Exonuc_VII_L PF02601.15 PRP84989.1 - 0.1 12.1 10.1 0.16 11.5 10.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Anp1 PF03452.14 PRP84989.1 - 0.23 10.8 3.7 0.34 10.3 3.7 1.2 1 0 0 1 1 1 0 Anp1 zf-CpG_bind_C PF12269.8 PRP84989.1 - 0.36 10.6 7.1 1.3 8.8 1.0 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain GRIM-19 PF06212.12 PRP84989.1 - 1.6 8.7 4.1 7.3 6.6 0.1 2.2 2 0 0 2 2 2 0 GRIM-19 protein I_LWEQ PF01608.17 PRP84989.1 - 2.1 8.6 11.2 3.3 7.9 11.2 1.2 1 0 0 1 1 1 0 I/LWEQ domain DUF16 PF01519.16 PRP84989.1 - 6.3 7.4 7.6 0.17 12.4 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 FAT PF02259.23 PRP84992.1 - 1e-84 284.8 1.4 1.2e-83 281.2 0.1 3.2 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 PRP84992.1 - 6.8e-67 225.9 0.1 1.8e-66 224.5 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 PRP84992.1 - 1.3e-40 138.9 7.7 6.8e-35 120.4 0.0 5.5 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 PRP84992.1 - 2.9e-34 117.4 0.3 2.9e-34 117.4 0.3 3.4 3 0 0 3 3 3 1 FKBP12-rapamycin binding domain FATC PF02260.20 PRP84992.1 - 1.2e-10 41.0 0.4 1.2e-10 41.0 0.4 2.0 2 0 0 2 2 1 1 FATC domain HEAT_2 PF13646.6 PRP84992.1 - 1.8e-08 34.6 16.8 0.0044 17.4 0.0 9.3 8 3 3 11 11 11 2 HEAT repeats MMS19_N PF14500.6 PRP84992.1 - 0.00019 21.1 0.4 0.26 10.8 0.0 4.3 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 PRP84992.1 - 0.00028 20.9 10.5 24 5.6 0.0 9.0 10 0 0 10 10 10 0 HEAT repeat IFRD PF05004.13 PRP84992.1 - 0.003 16.7 2.1 0.018 14.2 0.1 3.1 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) UME PF08064.13 PRP84992.1 - 0.019 14.9 0.0 16 5.5 0.0 4.9 3 1 1 4 4 4 0 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 PRP84992.1 - 0.03 14.9 0.5 10 6.8 0.0 5.0 5 0 0 5 5 4 0 Vacuolar 14 Fab1-binding region Ku_PK_bind PF08785.11 PRP84992.1 - 0.13 12.4 0.5 2.4 8.3 0.0 3.1 2 0 0 2 2 2 0 Ku C terminal domain like Sec7_N PF12783.7 PRP84992.1 - 1.1 9.1 3.5 3.2 7.7 0.2 3.6 5 0 0 5 5 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal WD40 PF00400.32 PRP84994.1 - 7.7e-21 74.0 7.7 0.0012 19.6 0.0 8.7 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP84994.1 - 0.00064 20.0 0.0 4.9 7.5 0.0 5.2 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain FCH PF00611.23 PRP84994.1 - 0.11 12.8 3.3 0.68 10.3 3.3 2.5 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DotU PF09850.9 PRP84994.1 - 0.29 10.8 3.7 0.12 12.1 0.4 2.0 2 0 0 2 2 2 0 Type VI secretion system protein DotU Ras PF00071.22 PRP84995.1 - 7.5e-60 201.2 0.1 9.4e-60 200.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP84995.1 - 6e-34 116.8 0.0 9e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP84995.1 - 9.6e-12 44.7 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP84995.1 - 7.2e-05 22.9 0.0 0.00035 20.6 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP84995.1 - 0.00092 19.2 0.2 0.22 11.4 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 PRP84995.1 - 0.0013 18.1 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PRP84995.1 - 0.014 15.8 0.1 0.026 14.9 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 PRP84995.1 - 0.18 10.9 0.1 0.96 8.5 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit CUE PF02845.16 PRP84996.1 - 2.2e-10 40.0 0.0 5.6e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 CUE domain YqzH PF14164.6 PRP84996.1 - 0.058 13.5 1.5 3.6 7.7 0.0 3.5 3 0 0 3 3 3 0 YqzH-like protein TRP PF06011.12 PRP84997.1 - 1.1e-10 40.9 0.0 0.091 11.5 0.0 3.7 3 1 0 3 3 3 3 Transient receptor potential (TRP) ion channel E1-E2_ATPase PF00122.20 PRP84997.1 - 1.3 8.5 20.1 0.34 10.4 0.8 4.4 3 1 1 4 4 4 0 E1-E2 ATPase EGF PF00008.27 PRP84997.1 - 3.5 8.0 13.0 0.97 9.8 4.6 2.5 2 0 0 2 2 2 0 EGF-like domain DUF3425 PF11905.8 PRP84998.1 - 2.5e-16 59.8 0.2 6.2e-16 58.5 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Asp PF00026.23 PRP84998.1 - 2.6e-12 46.8 0.1 3.9e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease F-box PF00646.33 PRP84998.1 - 6.9e-06 25.8 0.1 2.1e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 F-box domain bZIP_2 PF07716.15 PRP84998.1 - 7e-06 26.0 0.5 1.2e-05 25.2 0.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper F-box-like PF12937.7 PRP84998.1 - 9.5e-05 22.2 0.1 0.00025 20.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like bZIP_1 PF00170.21 PRP84998.1 - 0.0044 17.1 7.7 0.0083 16.2 7.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor TAXi_N PF14543.6 PRP84998.1 - 0.01 16.1 1.6 0.75 10.0 0.0 2.9 3 0 0 3 3 3 0 Xylanase inhibitor N-terminal bZIP_Maf PF03131.17 PRP84998.1 - 0.029 14.9 2.8 0.067 13.7 2.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor SVIP PF15811.5 PRP84998.1 - 0.055 13.9 0.3 0.1 13.1 0.3 1.4 1 0 0 1 1 1 0 Small VCP/p97-interacting protein BTB_2 PF02214.22 PRP85000.1 - 1.6e-21 76.4 0.1 3.3e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 PRP85000.1 - 5.1e-12 46.2 0.1 1.2e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 TLD BTB_3 PF16017.5 PRP85000.1 - 3.6e-06 27.0 0.0 6.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 PRP85000.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Baculo_PEP_C PF04513.12 PRP85001.1 - 0.017 15.2 33.6 0.048 13.7 9.2 4.6 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 PRP85001.1 - 0.028 14.6 0.9 0.028 14.6 0.9 7.2 2 2 5 7 7 7 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 PRP85001.1 - 0.037 12.9 80.6 0.05 12.5 16.5 4.1 2 1 2 4 4 4 0 Spc7 kinetochore protein FlaC_arch PF05377.11 PRP85001.1 - 0.042 14.2 1.6 0.042 14.2 1.6 8.0 6 2 3 9 9 9 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 PRP85001.1 - 0.058 13.4 0.1 0.058 13.4 0.1 5.6 5 2 4 9 9 9 0 Protein of unknown function (DUF1192) HsbA PF12296.8 PRP85001.1 - 0.65 10.4 9.2 11 6.4 0.1 4.0 3 1 0 4 4 4 0 Hydrophobic surface binding protein A DUF4763 PF15960.5 PRP85001.1 - 1.7 7.9 54.1 1.1 8.5 24.7 3.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4763) Sedlin_N PF04628.13 PRP85002.1 - 3.1e-21 75.9 0.4 3.3e-21 75.8 0.4 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 PRP85002.1 - 4.3e-08 33.2 0.2 4.7e-08 33.1 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family Kinesin PF00225.23 PRP85003.1 - 6.1e-99 331.1 1.2 1.2e-98 330.2 1.2 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PRP85003.1 - 1.6e-27 96.3 0.0 3.7e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding ACBP PF00887.19 PRP85004.1 - 8.4e-27 93.2 2.8 9.2e-27 93.1 2.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Taxilin PF09728.9 PRP85005.1 - 2.9e-62 210.6 78.1 2.9e-62 210.6 78.1 1.8 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF547 PF04784.14 PRP85005.1 - 0.061 13.4 4.7 0.12 12.5 4.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF547 zf-H2C2_5 PF13909.6 PRP85005.1 - 0.13 12.1 0.1 0.45 10.3 0.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF4250 PF14056.6 PRP85005.1 - 8.7 6.4 9.2 1.9 8.5 0.1 4.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4250) DELLA PF12041.8 PRP85005.1 - 9.4 6.2 7.0 37 4.3 0.0 4.4 4 1 1 5 5 5 0 Transcriptional regulator DELLA protein N terminal P16-Arc PF04699.14 PRP85006.1 - 2.6e-33 115.6 0.1 3.5e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 PRP85006.1 - 0.0027 18.0 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.10 PRP85006.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 UTP15 C terminal tRNA_int_endo PF01974.17 PRP85007.1 - 9.5e-16 57.6 0.0 1.7e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 PRP85007.1 - 0.00016 21.3 0.0 0.0018 17.9 0.0 2.3 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain TPR_18 PF13512.6 PRP85007.1 - 0.058 13.5 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 PRP85008.1 - 0.081 12.7 0.3 0.1 12.4 0.3 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF3043 PF11241.8 PRP85008.1 - 0.12 12.4 0.3 0.15 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) TMEM132D_C PF15706.5 PRP85008.1 - 0.84 9.5 4.6 0.31 10.8 1.4 1.8 1 1 1 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4229 PF14012.6 PRP85008.1 - 1.2 9.3 6.8 2.2 8.4 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) DAGK_cat PF00781.24 PRP85009.1 - 3.4e-31 107.5 0.1 7.5e-31 106.4 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Macoilin PF09726.9 PRP85009.1 - 0.36 9.3 9.3 0.46 9.0 9.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF3439 PF11921.8 PRP85009.1 - 0.77 9.7 6.5 1.7 8.6 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 PRP85009.1 - 3.7 5.4 6.7 5 5.0 6.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ank_4 PF13637.6 PRP85010.1 - 5e-14 52.5 0.0 4.5e-07 30.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85010.1 - 9e-13 48.2 0.3 2.8e-08 33.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP85010.1 - 6.7e-10 39.0 0.5 8.4e-06 26.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP85010.1 - 9e-10 38.0 0.0 0.00023 21.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 PRP85010.1 - 1.2e-09 38.6 0.0 2.6e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) RdRP PF05183.12 PRP85011.1 - 1.5e-102 344.2 2.5 1.7e-90 304.4 0.2 2.3 1 1 1 2 2 2 2 RNA dependent RNA polymerase Helicase_C PF00271.31 PRP85011.1 - 2.9e-12 46.9 0.3 7.4e-12 45.6 0.3 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP85011.1 - 6.1e-11 42.4 0.0 1.5e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP85011.1 - 3.9e-08 33.5 0.0 1.4e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M50B PF13398.6 PRP85011.1 - 3 7.4 8.4 38 3.8 0.4 3.6 4 0 0 4 4 4 0 Peptidase M50B-like LZ3wCH PF18517.1 PRP85012.1 - 0.038 14.1 2.4 6.3 7.0 0.0 3.2 2 2 1 3 3 3 0 Leucine zipper with capping helix domain DAO PF01266.24 PRP85013.1 - 4e-40 138.5 0.3 5.1e-40 138.1 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 PRP85013.1 - 2.3e-11 43.5 0.0 4.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_2 PF00890.24 PRP85013.1 - 1.2e-07 31.2 0.0 1.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 PRP85013.1 - 2.3e-07 30.9 1.2 7.5e-06 26.1 0.6 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PRP85013.1 - 2.7e-05 23.5 0.2 0.0005 19.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PRP85013.1 - 3.3e-05 23.4 0.2 4.7e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PRP85013.1 - 0.00033 20.0 0.7 0.00082 18.7 0.1 1.9 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 PRP85013.1 - 0.0015 17.3 0.2 0.0028 16.4 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 PRP85013.1 - 0.0023 17.2 0.7 0.0037 16.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PRP85013.1 - 0.0035 16.7 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PRP85013.1 - 0.0074 15.4 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 PRP85013.1 - 0.0078 16.8 0.1 0.069 13.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PRP85013.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF2695 PF10905.8 PRP85013.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Prok-RING_2 PF14445.6 PRP85013.1 - 0.12 12.5 0.2 0.32 11.2 0.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Gelsolin PF00626.22 PRP85014.1 - 3.4e-40 135.8 0.2 1e-10 41.3 0.0 5.6 5 0 0 5 5 5 5 Gelsolin repeat VHP PF02209.19 PRP85014.1 - 2e-14 53.4 1.2 6.3e-14 51.7 1.2 2.0 1 0 0 1 1 1 1 Villin headpiece domain TPR_14 PF13428.6 PRP85015.1 - 6.9e-08 32.7 11.7 0.027 15.2 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85015.1 - 5.5e-05 23.0 11.4 2.9 8.2 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP85015.1 - 9.2e-05 22.9 4.7 1.8 9.2 0.2 4.5 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP85015.1 - 0.00057 19.7 10.1 0.068 13.2 0.3 5.9 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP85015.1 - 0.0011 18.8 0.2 0.0011 18.8 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP85015.1 - 0.0016 18.2 3.8 4.7 7.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP85015.1 - 0.0078 16.5 3.8 0.0078 16.5 3.8 4.1 2 2 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP85015.1 - 0.031 14.5 3.4 34 5.0 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP85015.1 - 0.92 10.2 6.1 3.1 8.5 1.6 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Metallophos PF00149.28 PRP85016.1 - 3.4e-08 34.2 0.4 4.8e-08 33.8 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MARVEL PF01284.23 PRP85017.1 - 0.075 13.1 6.4 0.18 11.8 5.6 1.9 1 1 1 2 2 2 0 Membrane-associating domain RhoGEF PF00621.20 PRP85018.1 - 5.3e-43 147.4 1.2 1.1e-42 146.3 1.2 1.6 1 0 0 1 1 1 1 RhoGEF domain Ank_2 PF12796.7 PRP85018.1 - 4.5e-15 56.0 1.1 3.9e-06 27.3 0.1 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85018.1 - 1e-11 45.1 3.5 0.00014 22.3 0.3 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85018.1 - 6.8e-11 41.4 1.2 0.037 14.6 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PRP85018.1 - 1e-08 35.3 0.2 0.061 13.7 0.0 4.2 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP85018.1 - 2.1e-07 31.0 2.4 0.00073 19.9 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat PH PF00169.29 PRP85018.1 - 5.9e-05 23.5 0.0 0.00015 22.2 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_4 PF15404.6 PRP85018.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.4 3 1 0 3 3 2 0 Pleckstrin homology domain DDHD PF02862.17 PRP85018.1 - 0.32 11.1 5.3 0.97 9.6 5.3 1.9 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 PRP85018.1 - 0.51 10.1 25.5 0.99 9.2 25.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 PRP85018.1 - 0.57 9.7 25.7 0.32 10.6 23.6 1.7 2 0 0 2 2 2 0 PPP4R2 DUF2052 PF09747.9 PRP85018.1 - 1.4 9.0 32.7 0.059 13.5 25.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4050 PF13259.6 PRP85018.1 - 1.6 9.0 14.3 4.3 7.6 14.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF913 PF06025.12 PRP85018.1 - 2.7 6.9 10.1 1.9 7.4 8.2 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 PRP85018.1 - 2.9 7.8 39.3 6.4 6.7 39.3 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Neur_chan_memb PF02932.16 PRP85018.1 - 4 7.4 11.3 2.7 8.0 7.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 PRP85018.1 - 8.1 4.6 25.3 15 3.8 25.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 PRP85020.1 - 4.6e-55 184.2 0.9 7.8e-10 39.2 0.0 7.6 6 1 1 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85020.1 - 2e-35 120.7 14.4 0.0004 20.9 0.1 13.4 8 3 6 15 15 15 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85020.1 - 9.7e-25 86.3 17.8 0.023 15.0 0.1 13.9 8 4 8 16 16 16 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85020.1 - 7e-18 62.9 7.6 8.3 7.3 0.0 15.4 18 0 0 18 18 18 3 Ankyrin repeat Ank PF00023.30 PRP85020.1 - 6.4e-12 45.4 21.1 2.1 8.9 0.0 14.3 17 0 0 17 17 17 3 Ankyrin repeat ADSL_C PF10397.9 PRP85020.1 - 0.17 12.4 0.6 1.2e+02 3.3 0.0 5.3 4 3 1 5 5 5 0 Adenylosuccinate lyase C-terminus ApoO PF09769.9 PRP85021.1 - 3.4 7.6 24.8 1.6 8.7 1.7 5.6 4 1 0 5 5 5 0 Apolipoprotein O DUF2569 PF10754.9 PRP85023.1 - 0.03 14.8 6.7 0.26 11.7 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) DUF2663 PF10864.8 PRP85023.1 - 0.12 12.8 4.3 0.28 11.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) TMEM208_SND2 PF05620.11 PRP85023.1 - 7.9 6.2 6.2 6.8 6.5 0.1 2.3 1 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Saf_2TM PF18303.1 PRP85023.1 - 8.7 5.9 14.5 0.052 13.1 3.4 2.5 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Fructosamin_kin PF03881.14 PRP85024.1 - 4.9e-49 167.1 0.0 1.5e-46 159.0 0.0 2.3 1 1 0 1 1 1 1 Fructosamine kinase NmrA PF05368.13 PRP85024.1 - 2e-44 151.9 0.0 2.6e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP85024.1 - 3.2e-20 72.8 0.2 5e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PRP85024.1 - 0.0036 16.8 0.2 0.022 14.2 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 PRP85024.1 - 0.055 13.7 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 PRP85024.1 - 0.058 13.7 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 PRP85024.1 - 0.1 12.5 1.9 0.25 11.2 0.4 2.2 2 1 1 3 3 3 0 KR domain F420_oxidored PF03807.17 PRP85024.1 - 0.13 12.9 0.1 0.33 11.6 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Mub_B2 PF17966.1 PRP85024.1 - 0.14 12.9 0.2 0.34 11.7 0.2 1.7 1 0 0 1 1 1 0 Mub B2-like domain F-box PF00646.33 PRP85025.1 - 0.00012 21.8 0.3 0.00042 20.1 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP85025.1 - 0.0083 16.0 0.6 0.0083 16.0 0.6 2.3 3 0 0 3 3 3 1 F-box Spherulin4 PF12138.8 PRP85026.1 - 9.7e-52 176.0 3.7 1.3e-51 175.5 3.7 1.2 1 0 0 1 1 1 1 Spherulation-specific family 4 TMEM70 PF06979.12 PRP85027.1 - 0.0027 18.1 0.2 0.0044 17.4 0.2 1.4 1 1 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex BPD_transp_2 PF02653.16 PRP85027.1 - 0.0062 15.7 0.4 0.0096 15.1 0.4 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Ninjurin PF04923.12 PRP85027.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Ninjurin TMEM223 PF14640.6 PRP85027.1 - 0.063 13.4 0.3 0.11 12.7 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 Colicin_M PF14859.6 PRP85027.1 - 0.09 11.9 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Colicin M CLU PF13236.6 PRP85028.1 - 2.2e-53 181.4 0.0 4.5e-53 180.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP85028.1 - 4.2e-05 23.7 1.6 7.8e-05 22.8 0.5 2.1 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 DLH PF01738.18 PRP85029.1 - 1.2e-24 87.0 0.2 2.7e-17 63.0 0.0 2.0 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 PRP85029.1 - 0.00024 20.1 0.1 0.0021 17.0 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 PRP85029.1 - 0.0011 18.0 0.0 0.0036 16.4 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase ESSS PF10183.9 PRP85029.1 - 0.0025 18.0 0.0 0.044 14.0 0.0 2.3 2 0 0 2 2 2 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PRIMA1 PF16101.5 PRP85030.1 - 3.4 7.7 7.4 10 6.2 7.4 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HicA_toxin PF07927.12 PRP85032.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Homeodomain PF00046.29 PRP85033.1 - 3.6e-16 58.8 5.4 5.4e-16 58.2 5.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP85033.1 - 1.2e-07 31.4 0.3 2.9e-07 30.3 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain MRP-63 PF14978.6 PRP85033.1 - 0.052 14.2 1.3 0.079 13.6 1.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 PPTA PF01239.22 PRP85035.1 - 5e-39 130.9 13.2 5.3e-10 38.7 0.7 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Cylicin_N PF15241.6 PRP85035.1 - 0.057 13.6 1.7 0.79 9.9 0.1 2.4 2 0 0 2 2 2 0 Cylicin N-terminus Ank_2 PF12796.7 PRP85038.1 - 2e-27 95.6 0.0 1.2e-07 32.3 0.0 5.3 2 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP85038.1 - 5.8e-15 55.2 0.3 0.02 15.2 0.0 7.3 5 2 3 8 8 8 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP85038.1 - 2.1e-12 47.3 1.6 0.015 15.9 0.0 6.1 4 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP85038.1 - 1.3e-08 34.9 2.6 0.66 10.5 0.0 6.3 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 PRP85038.1 - 4.1e-06 26.7 0.6 8.3 7.3 0.0 6.3 7 0 0 7 7 7 1 Ankyrin repeat Oxysterol_BP PF01237.18 PRP85039.1 - 2.7e-81 273.3 0.1 3.6e-80 269.6 0.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 PRP85040.1 - 2.5e-10 40.8 0.7 2.5e-10 40.8 0.7 3.5 5 0 0 5 5 5 1 PH domain PH_11 PF15413.6 PRP85040.1 - 0.0018 18.6 5.1 0.0039 17.6 0.2 3.5 3 0 0 3 3 3 1 Pleckstrin homology domain Glyco_hydro_38N PF01074.22 PRP85041.1 - 1.8e-59 201.5 8.1 2.7e-59 200.9 8.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 PRP85041.1 - 5e-16 58.6 0.0 1.2e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 PRP85041.1 - 2.7e-14 53.7 0.0 1.8e-13 51.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 PRP85041.1 - 6.6e-10 39.0 0.0 1.5e-08 34.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain H_lectin PF09458.10 PRP85041.1 - 0.0049 17.0 0.6 0.016 15.4 0.6 1.9 1 0 0 1 1 1 1 H-type lectin domain Pkinase PF00069.25 PRP85042.1 - 4.4e-22 78.7 3.6 5.2e-13 49.0 0.0 4.0 2 2 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85042.1 - 5.1e-09 35.8 1.1 3.8e-05 23.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase F-box-like PF12937.7 PRP85042.1 - 1.6e-07 31.1 3.5 3.2e-07 30.1 3.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP85042.1 - 0.00011 22.0 0.8 0.00011 22.0 0.8 2.2 2 0 0 2 2 2 1 F-box domain 2_5_RNA_ligase2 PF13563.6 PRP85042.1 - 0.09 12.7 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Glyco_hydro_35 PF01301.19 PRP85043.1 - 5.6e-99 331.7 0.0 8.7e-99 331.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 PRP85043.1 - 2.9e-13 49.9 0.0 2e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase BetaGal_dom4_5 PF13364.6 PRP85043.1 - 0.00058 20.4 5.7 0.019 15.5 0.2 2.8 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain DEAD PF00270.29 PRP85044.1 - 6.3e-45 153.1 0.1 1.5e-44 151.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP85044.1 - 4.5e-32 110.7 0.0 1.4e-30 105.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP85044.1 - 1e-06 28.9 0.0 2.2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PRP85044.1 - 0.11 12.8 0.5 3.7 7.8 0.4 3.1 2 1 0 2 2 2 0 AAA domain Biopterin_H PF00351.21 PRP85045.1 - 3.3e-164 545.8 0.0 4.9e-164 545.2 0.0 1.3 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 PRP85045.1 - 6.6e-08 32.2 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain POC3_POC4 PF10448.9 PRP85045.1 - 0.054 13.5 0.5 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 ACT_4 PF13291.6 PRP85045.1 - 0.062 13.9 0.1 0.15 12.7 0.1 1.6 1 0 0 1 1 1 0 ACT domain Ank_2 PF12796.7 PRP85046.1 - 1.6e-36 124.7 0.2 9.6e-11 42.1 0.1 5.6 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85046.1 - 1.6e-27 95.5 5.9 4.3e-06 27.2 0.0 8.0 3 3 7 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85046.1 - 6.1e-17 61.5 9.2 0.02 15.2 0.1 8.5 5 2 4 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85046.1 - 2.3e-13 49.0 1.2 1.9 9.3 0.0 10.6 11 0 0 11 11 10 2 Ankyrin repeat Zn_clus PF00172.18 PRP85046.1 - 3.8e-13 49.3 32.4 2.2e-07 30.9 9.2 3.8 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank PF00023.30 PRP85046.1 - 3.6e-12 46.2 15.0 1.1 9.8 0.2 10.9 10 1 1 11 11 10 3 Ankyrin repeat HU-CCDC81_euk_1 PF14908.6 PRP85046.1 - 8.2e-05 22.7 1.3 5.2 7.3 0.0 3.6 3 0 0 3 3 3 1 CCDC81 eukaryotic HU domain 1 DUF5041 PF16444.5 PRP85046.1 - 0.0013 19.0 0.1 5 7.3 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF5041) Integrase_H2C2 PF17921.1 PRP85046.1 - 0.0049 16.9 0.6 36 4.6 0.0 4.2 3 0 0 3 3 3 0 Integrase zinc binding domain R3H-assoc PF13902.6 PRP85046.1 - 0.012 16.0 3.8 13 6.1 0.1 3.5 3 0 0 3 3 3 0 R3H-associated N-terminal domain DUF643 PF04867.12 PRP85046.1 - 0.014 16.0 0.1 34 5.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF643) PAS PF00989.25 PRP85046.1 - 0.051 13.6 0.0 19 5.3 0.0 3.2 3 0 0 3 3 3 0 PAS fold DUF3447 PF11929.8 PRP85046.1 - 0.055 13.4 0.0 2.6 8.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) PAS_8 PF13188.7 PRP85046.1 - 0.07 13.2 0.0 20 5.3 0.0 2.7 2 0 0 2 2 2 0 PAS domain HdeA PF06411.11 PRP85046.1 - 0.078 13.2 3.1 53 4.1 0.1 3.4 3 0 0 3 3 3 0 HdeA/HdeB family A_thal_3526 PF09713.10 PRP85046.1 - 0.21 11.9 2.1 1.1e+02 3.1 0.0 4.7 5 0 0 5 5 5 0 Plant protein 1589 of unknown function (A_thal_3526) Pkinase_Tyr PF07714.17 PRP85048.1 - 2.5e-52 177.7 0.1 1.1e-48 165.8 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 PRP85048.1 - 1.6e-30 106.4 0.0 8.5e-27 94.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain TMEM154 PF15102.6 PRP85048.1 - 0.0042 17.0 0.1 0.017 15.1 0.1 2.0 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.16 PRP85048.1 - 0.018 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E OmdA PF13376.6 PRP85049.1 - 2.2e-12 46.8 0.0 4.4e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated KRE1 PF17056.5 PRP85049.1 - 0.11 12.2 0.0 0.79 9.5 0.0 2.0 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 UPF0139 PF03669.13 PRP85050.1 - 1.1e-18 66.8 0.0 1.2e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) CrgA PF06781.12 PRP85050.1 - 0.082 13.0 0.0 1.5 8.9 0.0 2.1 1 1 0 1 1 1 0 Cell division protein CrgA Pkinase_Tyr PF07714.17 PRP85052.1 - 2e-78 263.3 0.0 3.2e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85052.1 - 1.1e-48 165.9 0.0 1.6e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP85052.1 - 3.4e-31 106.8 70.8 1.9e-10 40.3 5.4 13.0 10 3 3 14 14 14 10 Leucine rich repeat LRR_4 PF12799.7 PRP85052.1 - 1.4e-23 82.5 75.9 3.6e-05 24.0 0.8 14.9 8 5 7 16 16 16 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP85052.1 - 3.3e-07 29.9 68.9 0.11 13.1 0.1 18.9 19 2 0 19 19 19 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP85052.1 - 1.3e-05 24.9 52.3 0.035 14.2 0.9 14.8 17 0 0 17 17 17 4 Leucine Rich repeat Kinase-like PF14531.6 PRP85052.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FNIP PF05725.12 PRP85052.1 - 0.011 15.9 15.7 0.21 11.8 0.2 6.3 3 2 2 5 5 5 0 FNIP Repeat Haspin_kinase PF12330.8 PRP85052.1 - 0.012 14.5 0.0 0.031 13.2 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain DPBB_1 PF03330.18 PRP85053.1 - 1.7e-09 37.9 0.0 6e-09 36.1 0.0 2.1 1 0 0 1 1 1 1 Lytic transglycolase PAN_4 PF14295.6 PRP85053.1 - 4.3e-09 36.1 5.3 4.3e-09 36.1 5.3 2.9 3 0 0 3 3 3 1 PAN domain Chitin_bind_1 PF00187.19 PRP85053.1 - 1.2e-06 28.8 23.2 1.2e-06 28.8 23.2 3.0 3 1 0 3 3 3 1 Chitin recognition protein PAN_1 PF00024.26 PRP85053.1 - 3.1e-06 27.0 0.6 3.1e-06 27.0 0.6 2.2 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.11 PRP85053.1 - 0.00056 20.0 1.5 0.00056 20.0 1.5 2.7 2 1 0 2 2 2 1 PAN-like domain F-box PF00646.33 PRP85054.1 - 5.4e-06 26.1 2.9 5.8e-06 26.0 0.6 2.3 2 0 0 2 2 2 1 F-box domain Ank_4 PF13637.6 PRP85054.1 - 0.0021 18.6 1.9 2.1 9.1 0.1 5.3 5 2 0 5 5 5 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP85054.1 - 0.07 13.0 0.7 0.17 11.8 0.7 1.6 1 0 0 1 1 1 0 F-box-like HDNR PF15115.6 PRP85054.1 - 0.1 12.8 0.1 0.62 10.3 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function with conserved HDNR motif zf-C3HC4_2 PF13923.6 PRP85055.1 - 9.2e-09 35.0 11.6 1.4e-08 34.4 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP85055.1 - 2e-07 31.2 12.2 3.1e-07 30.6 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP85055.1 - 4.9e-06 26.3 9.2 7e-06 25.8 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP85055.1 - 5.8e-05 22.9 11.9 9.3e-05 22.2 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP85055.1 - 0.00013 22.2 9.9 0.00037 20.7 9.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP85055.1 - 0.00022 21.2 6.4 0.00022 21.2 6.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PRP85055.1 - 0.0034 17.5 12.8 0.0034 17.5 12.8 1.6 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING RRF_GI PF12614.8 PRP85055.1 - 0.017 15.3 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 Ribosome recycling factor zf-ANAPC11 PF12861.7 PRP85055.1 - 0.017 15.1 4.1 0.031 14.3 4.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PRP85055.1 - 0.028 14.3 10.0 0.046 13.6 10.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 PRP85055.1 - 0.037 13.8 4.7 0.062 13.1 4.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 PRP85055.1 - 0.23 11.5 10.4 0.38 10.7 10.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain YdfA_immunity PF12127.8 PRP85055.1 - 1.4 7.9 2.8 1.9 7.5 2.8 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial FYVE PF01363.21 PRP85055.1 - 2.4 8.4 9.7 4.6 7.5 9.4 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.6 PRP85055.1 - 4.3 7.2 10.1 9.5 6.1 10.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Hydrolase_6 PF13344.6 PRP85056.1 - 2.6e-30 104.5 0.0 5e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP85056.1 - 2.4e-18 66.0 0.0 6.2e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like PA14 PF07691.12 PRP85056.1 - 1.2e-11 44.6 0.0 2.8e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Hydrolase PF00702.26 PRP85056.1 - 9.1e-10 39.2 0.0 4.8e-09 36.8 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PRP85056.1 - 1.3e-06 28.6 0.0 0.00056 20.0 0.0 2.7 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Dicty_CTDC PF00526.18 PRP85056.1 - 0.0023 17.8 3.0 0.0023 17.8 3.0 7.3 9 0 0 9 9 9 1 Dictyostelium (slime mold) repeat Acid_phosphat_B PF03767.14 PRP85056.1 - 0.0067 16.0 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) PPR_2 PF13041.6 PRP85057.1 - 1.5e-05 25.1 1.2 0.2 11.8 0.0 3.6 3 0 0 3 3 3 2 PPR repeat family PPR PF01535.20 PRP85057.1 - 0.00025 21.1 0.1 1.8 9.0 0.0 3.9 3 0 0 3 3 3 2 PPR repeat DUF1281 PF06924.11 PRP85057.1 - 0.032 13.8 2.8 0.65 9.5 0.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1281) Peptidase_C54 PF03416.19 PRP85058.1 - 8.8e-94 314.0 0.0 1.6e-93 313.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C54 Glyco_hydro_43 PF04616.14 PRP85058.1 - 1.7e-48 165.4 10.8 3e-48 164.6 10.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Bin3 PF06859.12 PRP85058.1 - 1.2e-30 106.3 0.1 2.8e-30 105.1 0.1 1.7 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 PRP85058.1 - 5.6e-07 29.5 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP85058.1 - 1.1e-06 28.6 0.0 4.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP85058.1 - 2.1e-06 28.3 0.0 8.1e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP85058.1 - 0.0003 21.5 0.0 0.00087 20.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP85058.1 - 0.0018 18.8 0.0 0.0044 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PRP85058.1 - 0.0061 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 PRP85058.1 - 0.097 12.7 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 PRP85058.1 - 0.12 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PAN_1 PF00024.26 PRP85059.1 - 1.1e-09 38.1 1.2 0.0018 18.2 0.1 2.5 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 PRP85059.1 - 6.1e-08 32.5 14.5 3.8e-05 23.5 3.4 4.0 4 0 0 4 4 4 2 PAN domain fn3_6 PF17766.1 PRP85059.1 - 0.0034 17.5 0.0 3.7 7.8 0.0 2.5 2 0 0 2 2 2 2 Fibronectin type-III domain SLR1-BP PF07333.12 PRP85059.1 - 0.075 13.5 7.9 4 8.0 1.0 3.0 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) GCR1_C PF12550.8 PRP85059.1 - 0.12 12.7 0.0 5.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes AC_N PF16214.5 PRP85059.1 - 0.24 10.5 0.5 19 4.3 0.1 2.3 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Albumin_I PF08027.11 PRP85059.1 - 1.7 8.3 12.1 0.31 10.7 2.9 3.0 2 0 0 2 2 2 0 Albumin I chain b PAN_4 PF14295.6 PRP85061.1 - 1.1e-05 25.2 3.2 1.1e-05 25.2 3.2 2.6 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PRP85061.1 - 0.00012 22.0 0.1 0.00026 20.9 0.1 1.5 1 0 0 1 1 1 1 PAN domain PhoLip_ATPase_C PF16212.5 PRP85062.1 - 5.7e-71 239.2 25.5 5.7e-71 239.2 25.5 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP85062.1 - 3.4e-24 84.3 2.7 8e-24 83.1 2.7 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PRP85062.1 - 1.1e-10 42.2 1.7 4.2e-05 23.9 0.3 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PRP85062.1 - 2.3e-10 40.3 3.4 3.4e-10 39.7 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 PRP85062.1 - 1.2e-08 34.9 0.0 6.1e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP85062.1 - 0.00044 20.1 0.7 0.0029 17.4 0.0 2.3 2 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase ZZ PF00569.17 PRP85063.1 - 2.2e-18 65.8 24.6 7.3e-10 38.5 8.5 2.5 2 0 0 2 2 2 2 Zinc finger, ZZ type PB1 PF00564.24 PRP85063.1 - 0.0078 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 PB1 domain C1_2 PF03107.16 PRP85063.1 - 0.013 15.8 19.1 0.025 14.9 3.3 2.8 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 PRP85063.1 - 0.11 12.5 12.7 0.59 10.1 2.7 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_12 PF13424.6 PRP85064.1 - 0.0084 16.4 0.3 0.023 15.0 0.3 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85064.1 - 0.081 13.1 0.4 6.9 7.1 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PIG-Y PF15159.6 PRP85065.1 - 1.3e-15 58.0 2.6 1.6e-15 57.7 2.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y NDUF_B7 PF05676.13 PRP85067.1 - 4.7e-26 90.3 5.4 5.4e-26 90.1 5.4 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 PRP85067.1 - 0.021 14.9 1.6 0.027 14.5 1.6 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1682 PF07946.14 PRP85068.1 - 0.013 14.7 9.0 0.022 14.0 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Glycohydro_20b2 PF14845.6 PRP85068.1 - 1 10.0 4.3 0.79 10.4 1.9 1.9 2 0 0 2 2 2 0 beta-acetyl hexosaminidase like Cytomega_UL84 PF06284.11 PRP85068.1 - 2.5 6.5 6.3 3.6 5.9 6.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CobT PF06213.12 PRP85068.1 - 4.8 6.5 17.5 8.1 5.8 17.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pet100 PF09803.9 PRP85068.1 - 7 7.3 7.5 32 5.1 3.5 2.9 2 0 0 2 2 2 0 Pet100 CUE PF02845.16 PRP85070.1 - 1.4e-18 66.2 6.3 3.8e-07 29.7 0.1 5.1 5 0 0 5 5 5 3 CUE domain SKICH PF17751.1 PRP85070.1 - 1.6e-08 35.0 9.6 2.6e-05 24.7 1.3 3.9 3 0 0 3 3 3 2 SKICH domain HECW_N PF16562.5 PRP85070.1 - 3.5e-06 26.8 1.6 0.011 15.5 0.0 3.5 3 0 0 3 3 3 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 UBA_4 PF14555.6 PRP85070.1 - 6.5e-06 25.9 0.8 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 UBA-like domain HTH_8 PF02954.19 PRP85070.1 - 0.0099 15.7 0.9 0.14 12.0 0.0 3.0 3 0 0 3 3 3 1 Bacterial regulatory protein, Fis family HBS1_N PF08938.10 PRP85070.1 - 0.01 16.1 14.0 0.17 12.2 1.8 4.7 4 2 1 5 5 5 0 HBS1 N-terminus TAP_C PF03943.13 PRP85070.1 - 0.012 15.2 0.4 4.5 7.0 0.0 3.7 3 0 0 3 3 3 0 TAP C-terminal domain UBA PF00627.31 PRP85070.1 - 0.14 12.1 1.7 11 6.1 0.0 3.4 3 0 0 3 3 3 0 UBA/TS-N domain Pkinase PF00069.25 PRP85071.1 - 8.1e-48 163.1 0.0 2.5e-47 161.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85071.1 - 1.8e-24 86.5 0.0 2.9e-24 85.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Nuf2 PF03800.14 PRP85071.1 - 0.01 15.9 0.1 0.019 15.1 0.1 1.3 1 0 0 1 1 1 0 Nuf2 family pEK499_p136 PF18736.1 PRP85071.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 HEPN pEK499 p136 Sld7_C PF18596.1 PRP85071.1 - 0.021 15.0 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Sld7 C-terminal domain Peptidase_S41 PF03572.18 PRP85072.1 - 9.4e-09 35.0 0.0 3.9e-08 33.0 0.0 1.9 2 1 0 2 2 2 1 Peptidase family S41 Copine PF07002.16 PRP85073.1 - 1.9e-61 207.3 0.0 2.7e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 PRP85073.1 - 1.5e-09 38.3 0.1 2.4e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus PAN_4 PF14295.6 PRP85073.1 - 9.1e-05 22.3 2.6 9.1e-05 22.3 2.6 2.0 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PRP85073.1 - 0.00098 19.0 0.1 0.0024 17.8 0.1 1.6 1 0 0 1 1 1 1 PAN domain RasGAP PF00616.19 PRP85074.1 - 9.4e-31 107.1 14.2 5.4e-18 65.5 0.2 4.3 3 2 1 4 4 4 3 GTPase-activator protein for Ras-like GTPase DUF737 PF05300.11 PRP85074.1 - 0.13 12.6 6.4 0.045 14.1 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Spc7 PF08317.11 PRP85074.1 - 0.31 9.9 16.4 0.33 9.8 11.1 2.8 2 0 0 2 2 2 0 Spc7 kinetochore protein COMPASS-Shg1 PF05205.12 PRP85074.1 - 0.44 11.3 0.0 0.44 11.3 0.0 3.7 4 0 0 4 4 4 0 COMPASS (Complex proteins associated with Set1p) component shg1 Apolipoprotein PF01442.18 PRP85074.1 - 0.63 9.9 19.8 1.5 8.7 10.6 3.1 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 PRP85074.1 - 0.95 10.1 5.3 26 5.5 1.6 3.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ribosomal_L13e PF01294.18 PRP85074.1 - 5.4 6.8 7.4 5.9 6.7 3.0 2.8 3 0 0 3 3 3 0 Ribosomal protein L13e Baculo_PEP_C PF04513.12 PRP85074.1 - 9 6.3 15.0 5.3 7.1 1.5 4.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PQ-loop PF04193.14 PRP85075.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 PQ loop repeat EGF_2 PF07974.13 PRP85077.1 - 3.1e-05 24.3 6.8 3.1e-05 24.3 6.8 4.1 4 1 0 4 4 4 1 EGF-like domain ECH_1 PF00378.20 PRP85078.1 - 4.6e-44 150.6 0.0 5.4e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP85078.1 - 5.1e-25 88.7 0.0 6.6e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MA3 PF02847.17 PRP85078.1 - 0.015 15.3 0.0 6.9 6.7 0.0 2.3 2 0 0 2 2 2 0 MA3 domain UvrA_inter PF17760.1 PRP85078.1 - 0.15 12.2 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 UvrA interaction domain Bud13 PF09736.9 PRP85079.1 - 1.3e-38 132.6 18.1 1.3e-38 132.6 18.1 3.7 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex Methyltransf_16 PF10294.9 PRP85080.1 - 1.2e-29 103.3 0.0 4.6e-29 101.4 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase RhoGAP PF00620.27 PRP85080.1 - 3.7e-24 85.3 0.0 8.2e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 PRP85080.1 - 1.5e-20 73.7 6.1 1.2e-09 38.6 0.0 4.1 3 1 0 3 3 3 2 PH domain RhoGEF PF00621.20 PRP85080.1 - 4.9e-15 56.2 0.1 1.2e-14 54.9 0.1 1.7 1 0 0 1 1 1 1 RhoGEF domain T6SS_HCP PF05638.12 PRP85080.1 - 3.5e-12 46.8 0.0 3.7e-11 43.5 0.0 2.5 1 1 0 1 1 1 1 Type VI secretion system effector, Hcp Methyltransf_23 PF13489.6 PRP85080.1 - 3.4e-05 23.8 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PH_11 PF15413.6 PRP85080.1 - 0.00075 19.9 0.5 0.096 13.1 0.0 3.5 3 0 0 3 3 3 1 Pleckstrin homology domain MTS PF05175.14 PRP85080.1 - 0.0047 16.5 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PRP85080.1 - 0.0075 16.1 0.0 0.051 13.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain BAF PF02961.14 PRP85080.1 - 0.037 14.5 1.3 3.1 8.3 0.8 2.8 2 0 0 2 2 2 0 Barrier to autointegration factor Methyltransf_12 PF08242.12 PRP85080.1 - 0.14 12.9 0.0 0.38 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DNA_pol_A_exo1 PF01612.20 PRP85081.1 - 5.8e-19 68.5 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DUF3504 PF12012.8 PRP85081.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) RecO_C PF02565.15 PRP85081.1 - 0.068 13.0 0.5 0.26 11.1 0.4 2.1 1 1 1 2 2 2 0 Recombination protein O C terminal RabGAP-TBC PF00566.18 PRP85082.1 - 6.9e-53 179.5 4.4 1.1e-52 178.8 4.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 PRP85082.1 - 3.9e-29 101.1 2.9 8.3e-10 39.1 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP85082.1 - 7.6e-22 75.1 5.2 0.0021 18.4 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.6 PRP85082.1 - 3.1e-21 75.5 2.8 1.6e-08 34.9 0.5 5.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP85082.1 - 2.7e-16 59.2 6.2 0.0026 18.1 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 PRP85082.1 - 1.2e-14 54.1 5.6 3e-07 30.6 0.1 5.9 3 2 3 6 6 6 3 Ankyrin repeats (many copies) SapB_1 PF05184.15 PRP85082.1 - 0.18 11.8 1.4 19 5.4 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 BROMI PF14961.6 PRP85082.1 - 1.5 6.1 5.9 2.3 5.5 5.9 1.1 1 0 0 1 1 1 0 Broad-minded protein HTH_40 PF14493.6 PRP85083.1 - 0.00028 21.3 0.1 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain CCDC53 PF10152.9 PRP85083.1 - 0.062 13.7 1.2 0.13 12.7 0.4 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Terminase_5 PF06056.12 PRP85083.1 - 0.084 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) ESSS PF10183.9 PRP85083.1 - 0.087 13.0 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) LRR_8 PF13855.6 PRP85084.1 - 6.3e-22 77.1 39.3 2.5e-08 33.5 3.4 6.3 4 1 0 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 PRP85084.1 - 8.4e-14 51.5 48.9 0.00011 22.5 0.9 7.4 5 2 2 7 7 7 6 Leucine Rich repeats (2 copies) Plasmodium_HRP PF05403.11 PRP85084.1 - 2.7e-12 47.0 21.2 0.0092 15.8 3.5 5.9 1 1 2 3 3 3 3 Plasmodium histidine-rich protein (HRPII/III) LRR_1 PF00560.33 PRP85084.1 - 0.00011 22.2 18.9 3.7 8.5 0.0 8.3 8 0 0 8 8 8 2 Leucine Rich Repeat MMM1 PF10296.9 PRP85089.1 - 1.7e-13 50.4 4.0 5.6e-07 28.9 0.0 2.5 2 1 1 3 3 3 2 Maintenance of mitochondrial morphology protein 1 T5orf172 PF10544.9 PRP85089.1 - 0.048 14.2 1.7 0.072 13.6 0.2 2.1 2 0 0 2 2 2 0 T5orf172 domain FA_desaturase PF00487.24 PRP85089.1 - 0.13 12.1 2.1 0.087 12.7 0.4 1.6 2 0 0 2 2 2 0 Fatty acid desaturase RecG_N PF17190.4 PRP85089.1 - 0.18 12.5 0.2 0.18 12.5 0.2 2.3 2 0 0 2 2 2 0 RecG N-terminal helical domain CPDase PF07823.11 PRP85090.1 - 8e-08 32.2 0.0 1.8e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 PRP85090.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily Glyc_hyd_38C_2 PF18230.1 PRP85090.1 - 0.12 12.4 0.3 0.31 11.2 0.3 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal sub-domain WRKY PF03106.15 PRP85091.1 - 3.5e-26 91.2 16.6 4.9e-17 61.9 10.0 2.9 3 0 0 3 3 3 2 WRKY DNA -binding domain DUF3430 PF11912.8 PRP85092.1 - 0.31 11.0 7.0 0.1 12.6 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) DUF3430 PF11912.8 PRP85094.1 - 1.4 9.0 9.4 0.79 9.7 7.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3430) Rav1p_C PF12234.8 PRP85097.1 - 5.6e-82 276.1 0.1 3.9e-81 273.3 0.0 2.1 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.32 PRP85097.1 - 1.9e-17 63.3 13.1 0.21 12.5 0.0 10.2 10 1 1 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP85097.1 - 2.6e-06 27.6 0.7 0.022 15.1 0.0 4.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 PRP85097.1 - 0.06 12.9 0.1 1.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 ABC_tran PF00005.27 PRP85098.1 - 0.0036 17.8 0.0 0.0086 16.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PRP85098.1 - 0.011 16.2 0.0 0.034 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 PRP85098.1 - 0.024 13.6 0.0 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 PRP85098.1 - 0.033 13.4 0.0 0.075 12.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 PRP85098.1 - 0.039 14.0 0.0 0.093 12.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 PRP85098.1 - 0.072 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PIP5K PF01504.18 PRP85099.1 - 9.1e-76 254.7 0.0 3.4e-75 252.8 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Ank_4 PF13637.6 PRP85099.1 - 3.7e-19 68.8 0.6 1.1e-08 35.5 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85099.1 - 5.8e-16 58.3 0.6 9.5e-07 29.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP85099.1 - 2.4e-15 56.9 0.0 1.8e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 PRP85099.1 - 3.8e-15 55.6 0.9 0.025 15.0 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 PRP85099.1 - 9.2e-11 41.0 0.2 0.12 13.0 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat EF-hand_1 PF00036.32 PRP85099.1 - 1.2e-07 30.8 0.0 0.072 12.7 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 PRP85099.1 - 9.2e-07 28.1 0.1 0.01 15.3 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PRP85099.1 - 3e-06 27.6 0.1 0.00014 22.2 0.0 3.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP85099.1 - 1.6e-05 24.4 0.0 0.5 10.4 0.0 3.4 3 0 0 3 3 2 2 EF-hand domain EF-hand_8 PF13833.6 PRP85099.1 - 5e-05 23.1 0.4 0.042 13.7 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain pair DUF4773 PF15998.5 PRP85100.1 - 9.6e-17 61.6 1.1 3e-16 60.0 1.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4773) DSPc PF00782.20 PRP85101.1 - 1.1e-29 102.9 0.0 2.1e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP85101.1 - 8.3e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.14 PRP85101.1 - 0.012 15.8 0.1 0.031 14.5 0.1 1.7 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.6 PRP85101.1 - 0.094 12.2 0.2 0.3 10.6 0.2 1.8 1 0 0 1 1 1 0 zinc-ribbon domain Init_tRNA_PT PF04179.12 PRP85101.1 - 0.1 12.9 0.1 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 Rit1 DUSP-like domain GSDH PF07995.11 PRP85103.1 - 2.8e-22 79.5 0.0 1.5e-20 73.8 0.0 3.0 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 PRP85103.1 - 1.6e-16 59.9 21.2 3e-09 36.6 0.7 4.3 4 0 0 4 4 4 2 PKD domain X8 PF07983.13 PRP85103.1 - 4.1e-10 40.2 2.0 9.3e-10 39.1 2.0 1.7 1 0 0 1 1 1 1 X8 domain RIFIN PF02009.16 PRP85103.1 - 0.5 10.2 4.9 0.52 10.1 3.2 1.8 2 0 0 2 2 2 0 Rifin Patatin PF01734.22 PRP85104.1 - 3.1e-23 83.0 0.3 9.3e-23 81.5 0.3 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase SAT PF16073.5 PRP85104.1 - 0.12 12.1 0.0 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis LAG1-DNAbind PF09271.11 PRP85105.1 - 9.9e-05 23.0 0.0 0.63 10.7 0.0 2.4 2 0 0 2 2 2 2 LAG1, DNA binding ITAM PF02189.15 PRP85105.1 - 5.9 7.6 6.9 22 5.8 0.2 2.8 3 0 0 3 3 3 0 Immunoreceptor tyrosine-based activation motif GSDH PF07995.11 PRP85107.1 - 1.6e-32 113.1 0.0 3.4e-32 112.1 0.0 1.4 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Carb_bind PF10645.9 PRP85107.1 - 0.00053 20.1 60.3 0.0085 16.3 15.4 5.4 4 1 1 5 5 5 3 Carbohydrate binding PQQ_3 PF13570.6 PRP85107.1 - 0.17 12.4 6.5 5.2 7.7 0.1 3.9 3 0 0 3 3 3 0 PQQ-like domain PPR_2 PF13041.6 PRP85109.1 - 8.4e-25 86.7 7.7 2.1e-10 40.6 0.5 5.0 2 2 3 5 5 5 5 PPR repeat family PPR_3 PF13812.6 PRP85109.1 - 1.5e-20 73.0 4.0 2.6e-09 37.0 0.0 4.0 4 1 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 PRP85109.1 - 1.2e-14 53.4 12.2 0.0007 19.7 0.2 6.2 5 2 1 6 6 6 3 PPR repeat PPR_1 PF12854.7 PRP85109.1 - 8.1e-14 51.0 0.1 0.019 14.6 0.0 5.4 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 PRP85109.1 - 2.3e-11 43.5 0.0 3.3e-09 36.4 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP Fic_N PF13784.6 PRP85109.1 - 0.0042 17.1 0.1 0.71 10.0 0.0 2.6 2 0 0 2 2 2 1 Fic/DOC family N-terminal Ins_allergen_rp PF06757.13 PRP85109.1 - 0.0057 16.6 0.5 3.2 7.7 0.1 2.8 2 1 0 2 2 2 2 Insect allergen related repeat, nitrile-specifier detoxification Exog_C PF18026.1 PRP85109.1 - 0.04 14.0 0.2 6.8 6.8 0.0 4.0 5 0 0 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain ENT PF03735.14 PRP85109.1 - 0.041 14.0 0.1 3.5 7.8 0.0 2.8 2 1 1 3 3 3 0 ENT domain Clathrin PF00637.20 PRP85109.1 - 0.048 13.5 0.2 2.9 7.7 0.0 2.5 1 1 1 2 2 2 0 Region in Clathrin and VPS AAA_34 PF13872.6 PRP85109.1 - 0.07 12.0 0.1 0.7 8.7 0.0 2.2 2 1 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 DUF1884 PF08967.10 PRP85109.1 - 0.11 12.8 0.0 26 5.2 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1884) UBX PF00789.20 PRP85109.1 - 0.16 12.2 0.2 21 5.4 0.0 2.8 3 0 0 3 3 3 0 UBX domain Fimbrillin_C PF15495.6 PRP85109.1 - 1.4 9.4 5.8 12 6.4 0.4 3.4 3 2 0 3 3 3 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal WD40 PF00400.32 PRP85110.1 - 6.9e-30 102.7 10.9 6.8e-06 26.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Homeodomain PF00046.29 PRP85110.1 - 1.7e-14 53.4 3.7 1.7e-14 53.4 3.7 2.6 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 PRP85110.1 - 4.2e-07 29.8 0.7 9.9e-07 28.6 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain Nup160 PF11715.8 PRP85110.1 - 2.2e-05 23.3 0.9 3.5 6.1 0.0 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 BrkDBD PF09607.10 PRP85110.1 - 5.7e-05 22.8 0.2 0.00015 21.5 0.2 1.6 1 0 0 1 1 1 1 Brinker DNA-binding domain WD40_like PF17005.5 PRP85110.1 - 0.00029 20.3 0.0 0.03 13.6 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 PRP85110.1 - 0.0088 16.3 0.1 11 6.4 0.0 3.5 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Golgin_A5 PF09787.9 PRP85110.1 - 0.016 14.7 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-B_N PF04218.13 PRP85110.1 - 0.022 14.4 0.2 0.052 13.2 0.2 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain BBS2_Mid PF14783.6 PRP85110.1 - 0.087 12.9 0.0 1.2 9.2 0.0 2.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region p450 PF00067.22 PRP85111.1 - 4.2e-87 292.8 0.1 5e-87 292.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHC PF09626.10 PRP85111.1 - 0.12 13.2 0.2 0.45 11.4 0.1 1.9 2 0 0 2 2 2 0 Dihaem cytochrome c CHASE9 PF17153.4 PRP85111.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular START PF01852.19 PRP85112.1 - 0.0003 20.2 0.0 0.00064 19.2 0.0 1.5 1 0 0 1 1 1 1 START domain Casc1_N PF15927.5 PRP85112.1 - 0.23 11.1 1.8 2.8 7.6 0.5 2.2 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Pkinase PF00069.25 PRP85113.1 - 3.5e-40 138.1 0.0 5e-40 137.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85113.1 - 3e-18 66.0 0.0 3.6e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP85113.1 - 0.016 14.5 0.1 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 PRP85113.1 - 0.031 13.6 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homeodomain PF00046.29 PRP85114.1 - 1.3e-16 60.2 1.3 2.9e-16 59.1 1.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP85114.1 - 1.5e-07 31.2 0.5 3e-07 30.2 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain BrkDBD PF09607.10 PRP85114.1 - 4.4e-05 23.2 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_23 PF13384.6 PRP85114.1 - 0.054 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Spem1 PF15670.5 PRP85114.1 - 0.9 9.1 4.8 0.18 11.3 1.4 1.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 Pkinase PF00069.25 PRP85115.1 - 3.8e-64 216.6 0.0 4.6e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85115.1 - 1.6e-39 135.7 0.0 2.2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP85115.1 - 1.1e-06 28.2 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP85115.1 - 3.7e-05 23.8 0.0 0.0013 18.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP85115.1 - 3.9e-05 23.1 0.1 0.00011 21.6 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP85115.1 - 0.00044 19.3 0.4 0.00065 18.7 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP85115.1 - 0.00064 18.6 0.0 0.00094 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 PRP85115.1 - 0.18 11.3 0.1 0.68 9.5 0.0 1.8 1 1 0 2 2 2 0 Choline/ethanolamine kinase Homeodomain PF00046.29 PRP85117.1 - 1.9e-32 110.8 20.2 3.1e-17 62.1 4.0 3.4 3 0 0 3 3 3 2 Homeodomain Homeobox_KN PF05920.11 PRP85117.1 - 2.5e-12 46.5 11.7 1.1e-06 28.5 2.4 2.7 3 0 0 3 3 3 2 Homeobox KN domain BrkDBD PF09607.10 PRP85117.1 - 2.4e-10 40.0 2.3 0.00075 19.2 0.2 3.3 3 0 0 3 3 3 2 Brinker DNA-binding domain CENP-B_N PF04218.13 PRP85117.1 - 1.1e-07 31.4 0.5 0.0069 16.0 0.1 3.3 3 0 0 3 3 3 2 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.6 PRP85117.1 - 0.00011 22.2 0.4 0.4 10.8 0.1 2.8 3 0 0 3 3 3 2 Helix-turn-helix domain HTH_OrfB_IS605 PF12323.8 PRP85117.1 - 0.00069 19.1 0.6 0.79 9.3 0.1 2.6 2 0 0 2 2 2 2 Helix-turn-helix domain YdaS_antitoxin PF15943.5 PRP85117.1 - 0.026 14.4 0.2 9.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_36 PF13730.6 PRP85117.1 - 0.03 14.3 0.0 13 5.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 PRP85117.1 - 0.034 13.9 0.6 8.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Homeodomain-like domain Homeodomain PF00046.29 PRP85118.1 - 4.9e-17 61.5 3.5 9.7e-17 60.6 3.5 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP85118.1 - 1.4e-07 31.3 1.3 3.1e-07 30.2 1.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain BrkDBD PF09607.10 PRP85118.1 - 0.00016 21.3 0.1 0.00038 20.2 0.1 1.5 1 0 0 1 1 1 1 Brinker DNA-binding domain MRP-L20 PF12824.7 PRP85118.1 - 0.0085 16.3 0.6 0.52 10.5 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Ank_2 PF12796.7 PRP85119.1 - 3.1e-26 91.8 0.0 8.4e-11 42.3 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP85119.1 - 4.4e-12 46.0 0.4 0.011 16.0 0.0 4.7 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP85119.1 - 2.1e-08 34.5 0.2 3.2e-06 27.6 0.0 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85119.1 - 4.6e-08 32.7 0.3 1.2 9.9 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 PRP85119.1 - 5e-08 33.0 0.4 0.23 12.0 0.0 4.6 3 2 1 4 4 4 3 Ankyrin repeat DUF3447 PF11929.8 PRP85119.1 - 0.011 15.7 0.0 0.48 10.4 0.0 2.8 1 1 3 4 4 4 0 Domain of unknown function (DUF3447) MMS1_N PF10433.9 PRP85120.1 - 8.2e-95 318.3 0.4 1.8e-94 317.2 0.1 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PRP85120.1 - 8.7e-72 242.1 0.1 6.3e-71 239.3 0.0 2.2 1 1 1 2 2 2 1 CPSF A subunit region Bacillus_HBL PF05791.11 PRP85120.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Uso1_p115_C PF04871.13 PRP85121.1 - 0.0013 19.1 13.3 0.0027 18.1 8.0 2.4 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 PRP85121.1 - 0.002 18.2 9.2 0.012 15.6 0.4 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Acyl-CoA_dh_2 PF08028.11 PRP85121.1 - 0.016 15.5 3.0 0.02 15.1 0.3 2.2 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF16 PF01519.16 PRP85121.1 - 0.031 14.8 11.9 0.089 13.3 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF4200 PF13863.6 PRP85121.1 - 0.034 14.6 13.9 0.26 11.7 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Laminin_II PF06009.12 PRP85121.1 - 0.063 13.3 8.0 2 8.4 0.3 2.6 2 1 0 2 2 2 0 Laminin Domain II DUF745 PF05335.13 PRP85121.1 - 0.066 12.9 8.2 0.59 9.8 1.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.11 PRP85121.1 - 0.069 13.7 7.1 2.8 8.5 2.1 3.0 1 1 1 3 3 3 0 Syntaxin 6, N-terminal APG17 PF04108.12 PRP85121.1 - 0.073 12.2 8.4 0.07 12.2 0.5 2.7 1 1 0 2 2 2 0 Autophagy protein Apg17 SNARE PF05739.19 PRP85121.1 - 0.077 13.0 3.6 0.22 11.5 3.6 1.8 1 0 0 1 1 1 0 SNARE domain SKA1 PF07160.12 PRP85121.1 - 0.091 12.6 7.3 0.88 9.4 0.2 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Ran-binding PF05508.11 PRP85121.1 - 0.21 10.5 3.0 0.64 8.9 0.1 2.2 2 0 0 2 2 2 0 RanGTP-binding protein DUF4201 PF13870.6 PRP85121.1 - 0.26 11.0 10.4 0.38 10.5 2.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.12 PRP85121.1 - 0.4 10.7 7.0 0.34 11.0 0.4 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1479 PF07350.12 PRP85121.1 - 0.44 9.3 1.7 0.78 8.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Bacillus_HBL PF05791.11 PRP85121.1 - 0.47 10.3 9.9 2.9 7.7 0.4 3.0 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF2730 PF10805.8 PRP85121.1 - 0.7 10.0 5.8 2.7 8.1 0.0 3.7 2 1 1 4 4 4 0 Protein of unknown function (DUF2730) COG6 PF06419.11 PRP85121.1 - 1.4 7.1 8.7 1.8 6.7 0.6 2.1 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Snapin_Pallidin PF14712.6 PRP85121.1 - 1.6 9.2 7.9 0.72 10.3 0.4 3.0 2 1 1 3 3 3 0 Snapin/Pallidin YscO PF07321.12 PRP85121.1 - 2.5 8.0 14.4 0.96 9.4 9.5 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO Fib_alpha PF08702.10 PRP85121.1 - 2.9 8.1 5.5 33 4.7 0.1 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 PRP85121.1 - 3.3 8.3 7.9 5.2 7.6 1.0 3.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.21 PRP85121.1 - 4 8.0 10.0 12 6.4 4.1 3.1 2 2 1 3 3 3 0 Spectrin repeat DUF5089 PF17002.5 PRP85121.1 - 4.9 7.0 11.3 1.8 8.4 7.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) KxDL PF10241.9 PRP85121.1 - 8.4 6.8 11.4 7 7.0 0.6 3.5 2 2 1 3 3 3 0 Uncharacterized conserved protein Ammonium_transp PF00909.21 PRP85122.1 - 1.3e-86 290.8 29.0 5e-86 288.9 29.0 1.7 1 1 0 1 1 1 1 Ammonium Transporter Family Synapsin_C PF02750.14 PRP85122.1 - 5.2e-34 117.6 0.0 1.1e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 Synapsin, ATP binding domain Synapsin PF02078.16 PRP85122.1 - 6.3e-16 58.5 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Synapsin, N-terminal domain ATP-grasp PF02222.22 PRP85122.1 - 0.00099 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain T4SS_CagC PF16943.5 PRP85122.1 - 0.037 14.2 4.3 0.72 10.1 0.0 3.2 2 1 0 2 2 2 0 Cag pathogenicity island, type IV secretory system TMEM220 PF15071.6 PRP85122.1 - 0.13 13.0 4.1 0.17 12.7 0.9 2.7 2 0 0 2 2 2 0 Transmembrane family 220, helix RDD PF06271.12 PRP85122.1 - 0.17 12.1 3.1 0.67 10.1 2.3 2.4 2 0 0 2 2 2 0 RDD family MASE2 PF05230.11 PRP85122.1 - 5.6 7.1 6.9 0.76 9.9 1.9 2.2 2 0 0 2 2 2 0 MASE2 domain HetR_C PF18460.1 PRP85123.1 - 0.0017 18.3 0.1 0.004 17.0 0.1 1.7 1 0 0 1 1 1 1 Heterocyst differentiation regulator C-terminal Hood domain DUF222 PF02720.17 PRP85123.1 - 0.016 14.7 1.7 0.02 14.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF222) DRTGG PF07085.12 PRP85123.1 - 0.031 14.1 0.8 0.07 12.9 0.4 1.7 1 1 1 2 2 2 0 DRTGG domain WDCP PF15390.6 PRP85123.1 - 0.06 11.7 7.0 0.067 11.6 7.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Seryl_tRNA_N PF02403.22 PRP85123.1 - 0.084 13.1 20.1 0.093 13.0 5.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DASH_Spc34 PF08657.10 PRP85123.1 - 0.35 10.6 11.4 0.42 10.4 11.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 DUF3584 PF12128.8 PRP85123.1 - 0.4 8.1 17.7 0.44 8.0 17.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0515 PF15135.6 PRP85123.1 - 0.44 9.8 6.1 0.42 9.9 5.3 1.3 1 1 0 1 1 1 0 Uncharacterised protein UPF0515 UPF0242 PF06785.11 PRP85123.1 - 0.54 10.3 19.0 1 9.5 18.2 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ABC2_membrane_3 PF12698.7 PRP85123.1 - 0.78 8.8 6.0 0.93 8.5 6.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4407 PF14362.6 PRP85123.1 - 1.1 8.6 12.5 1.4 8.2 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 PRP85123.1 - 2.2 8.7 16.7 0.17 12.3 7.6 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF948 PF06103.11 PRP85123.1 - 2.5 8.4 9.9 0.51 10.6 2.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_lysozyme2 PF18013.1 PRP85123.1 - 3 7.8 7.4 0.76 9.8 1.1 2.0 1 1 1 2 2 2 0 Phage tail lysozyme TolA_bind_tri PF16331.5 PRP85123.1 - 3.4 7.8 15.4 0.24 11.5 6.8 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation MRPL52 PF18699.1 PRP85123.1 - 4.5 7.5 11.6 0.35 11.1 5.0 2.2 1 1 1 2 2 2 0 Mitoribosomal protein mL52 PRKG1_interact PF15898.5 PRP85123.1 - 5.5 8.0 16.7 0.41 11.6 6.6 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain zf-CCCH PF00642.24 PRP85124.1 - 2.3e-21 75.2 15.4 2.8e-11 43.0 5.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PRP85124.1 - 1.9e-14 53.0 9.8 4.6e-07 29.5 1.8 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PRP85124.1 - 1.2e-12 47.4 15.0 4e-06 26.7 4.8 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 PRP85124.1 - 0.00035 20.9 8.4 0.13 12.7 0.4 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PRP85124.1 - 0.0041 17.8 12.5 0.037 14.7 1.1 2.8 1 1 2 3 3 3 2 Torus domain U-box PF04564.15 PRP85125.1 - 0.00028 21.0 0.1 0.0016 18.6 0.0 2.2 2 0 0 2 2 2 1 U-box domain Myb_DNA-binding PF00249.31 PRP85125.1 - 0.0004 20.5 0.0 0.0015 18.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain RXT2_N PF08595.11 PRP85125.1 - 0.0009 19.3 1.9 0.0009 19.3 1.9 2.7 3 1 1 4 4 4 1 RXT2-like, N-terminal DTHCT PF08070.11 PRP85125.1 - 0.0034 18.1 12.7 0.0034 18.1 12.7 3.0 4 1 0 4 4 4 1 DTHCT (NUC029) region DUF3106 PF11304.8 PRP85125.1 - 0.0093 16.4 2.5 0.022 15.2 2.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3106) ATG7_N PF16420.5 PRP85125.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.2 2 1 1 3 3 3 0 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus LAG1-DNAbind PF09271.11 PRP85126.1 - 0.14 12.7 0.0 0.23 12.1 0.0 1.5 1 1 0 1 1 1 0 LAG1, DNA binding GBP PF02263.19 PRP85126.1 - 0.16 11.2 0.1 1.4 8.1 0.1 1.9 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Phospho_p8 PF10195.9 PRP85127.1 - 0.2 12.2 0.0 0.32 11.5 0.0 1.3 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 DUF2009 PF09418.10 PRP85128.1 - 3.9e-205 682.2 0.0 4.7e-205 681.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) SAM_2 PF07647.17 PRP85128.1 - 7.9e-07 29.1 0.3 1.1e-05 25.5 0.1 2.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP85128.1 - 5.2e-05 23.6 0.1 0.00017 21.9 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) UPF0227 PF05728.12 PRP85129.1 - 0.072 13.0 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 PRP85129.1 - 0.098 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cortex-I_coil PF09304.10 PRP85132.1 - 0.092 13.0 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Lung_7-TM_R PF06814.13 PRP85135.1 - 7.9e-08 31.9 20.7 2.6e-07 30.2 20.7 1.9 1 1 0 1 1 1 1 Lung seven transmembrane receptor FAM212 PF15342.6 PRP85136.1 - 0.035 13.9 0.1 0.041 13.7 0.1 1.2 1 0 0 1 1 1 0 FAM212 family DUF2252 PF10009.9 PRP85139.1 - 0.01 14.9 0.2 0.019 14.1 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Pkinase PF00069.25 PRP85140.1 - 9.7e-61 205.4 0.3 2.2e-60 204.3 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 PRP85140.1 - 3.1e-33 115.5 4.8 4e-33 115.1 3.3 2.1 2 0 0 2 2 2 1 RasGEF domain Pkinase_Tyr PF07714.17 PRP85140.1 - 2.1e-27 96.1 0.7 3.6e-27 95.3 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Rap_GAP PF02145.15 PRP85140.1 - 8.5e-22 77.6 0.1 2.1e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Ank_2 PF12796.7 PRP85140.1 - 3e-15 56.6 0.0 5e-08 33.4 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP85140.1 - 2.6e-14 51.9 0.0 0.00035 20.8 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 PRP85140.1 - 2.2e-13 50.4 1.9 2.1e-06 28.2 0.0 4.2 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85140.1 - 3e-12 46.5 0.2 5.9e-05 23.3 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP85140.1 - 8.8e-12 44.9 0.1 0.00012 22.4 0.0 4.3 4 0 0 4 4 3 3 Ankyrin repeat RasGEF_N PF00618.20 PRP85140.1 - 1e-07 32.1 0.6 3.7e-07 30.3 0.6 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH2 PF00017.24 PRP85140.1 - 5.7e-05 23.1 0.2 0.00039 20.5 0.0 2.6 3 0 0 3 3 2 1 SH2 domain Kdo PF06293.14 PRP85140.1 - 0.00026 20.4 0.2 0.00072 19.0 0.2 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP85140.1 - 0.0036 16.9 0.4 0.013 15.1 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 PRP85140.1 - 0.004 17.1 0.0 0.015 15.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP85140.1 - 0.025 14.2 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 RIO1 family 4HBT_3 PF13622.6 PRP85141.1 - 7.9e-58 196.6 0.1 1.2e-57 196.0 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 PRP85141.1 - 3.7e-26 91.5 0.0 2.1e-20 72.9 0.0 2.7 2 1 0 2 2 2 2 Acyl-CoA thioesterase MORN PF02493.20 PRP85145.1 - 2.2e-74 241.1 117.4 9.7e-07 28.3 2.0 17.2 17 0 0 17 17 17 14 MORN repeat F-box-like PF12937.7 PRP85145.1 - 2.3e-09 37.0 3.1 2.3e-09 37.0 3.1 1.9 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 PRP85145.1 - 0.00027 20.8 0.2 0.00027 20.8 0.2 2.1 2 0 0 2 2 2 1 F-box F-box PF00646.33 PRP85145.1 - 0.012 15.4 3.5 0.026 14.4 3.5 1.5 1 0 0 1 1 1 0 F-box domain TMF_DNA_bd PF12329.8 PRP85145.1 - 0.014 15.3 3.5 0.014 15.3 3.5 5.9 3 3 2 5 5 5 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.18 PRP85145.1 - 0.86 10.0 20.0 3 8.2 1.5 5.0 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF3584 PF12128.8 PRP85145.1 - 3.9 4.9 47.2 6.3 4.2 47.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ubiquitin PF00240.23 PRP85147.1 - 5.4e-20 70.9 0.2 1.6e-19 69.4 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PRP85147.1 - 2.1e-08 33.9 0.4 4.7e-08 32.8 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP85147.1 - 0.0006 20.2 0.1 0.0015 19.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 PRP85147.1 - 0.0014 19.1 0.1 0.0055 17.3 0.1 2.0 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP85147.1 - 0.013 15.8 0.1 0.05 14.0 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 PRP85147.1 - 0.014 15.3 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Dak2 PF02734.17 PRP85147.1 - 0.016 15.1 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 DAK2 domain Rad60-SLD_2 PF13881.6 PRP85147.1 - 0.024 14.7 1.5 0.07 13.2 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 PRP85147.1 - 0.13 12.3 0.1 2.6 8.2 0.1 2.4 1 1 1 2 2 2 0 Ubiquitin-like domain Sulfate_transp PF00916.20 PRP85148.1 - 1.7e-12 46.8 16.0 1.7e-12 46.8 16.0 2.2 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 PRP85148.1 - 9.4e-11 41.4 0.0 5e-10 39.0 0.0 2.2 2 1 0 2 2 2 1 STAS domain cNMP_binding PF00027.29 PRP85148.1 - 5.4e-07 29.6 0.0 9.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NiFe_hyd_3_EhaA PF17367.2 PRP85148.1 - 0.0017 18.5 4.0 0.0079 16.3 4.0 2.2 1 0 0 1 1 1 1 NiFe-hydrogenase-type-3 Eha complex subunit A Chlorovi_GP_rpt PF06598.11 PRP85148.1 - 0.27 11.3 1.7 0.98 9.5 0.3 2.7 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat S1-P1_nuclease PF02265.16 PRP85149.1 - 3.6e-55 187.5 0.0 4.3e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF4248 PF14053.6 PRP85149.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) AdoMet_MTase PF07757.13 PRP85150.1 - 5.8e-32 110.4 0.1 1.1e-31 109.4 0.1 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 PRP85150.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 PRP85150.1 - 0.032 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 PRP85150.1 - 0.032 14.2 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 PRP85150.1 - 0.11 13.2 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2052 PF09747.9 PRP85151.1 - 0.0088 16.2 3.2 0.01 15.9 3.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.16 PRP85151.1 - 0.19 11.7 4.4 0.27 11.3 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 PRP85151.1 - 0.23 11.2 6.9 0.29 10.9 6.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 PRP85151.1 - 6.1 5.5 5.4 6.7 5.4 5.4 1.1 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 PRP85153.1 - 1.8e-32 111.7 1.2 1.2e-10 41.8 0.0 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85153.1 - 5.9e-18 65.0 3.6 0.00066 20.2 0.0 6.3 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP85153.1 - 6.7e-15 54.8 5.2 0.96 10.0 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 PRP85153.1 - 1.3e-13 49.8 4.4 0.42 11.3 0.0 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 PRP85153.1 - 9.4e-11 41.7 6.9 0.062 13.6 0.0 7.6 2 2 6 8 8 8 3 Ankyrin repeats (many copies) DUF3447 PF11929.8 PRP85153.1 - 0.0017 18.3 0.1 0.014 15.3 0.1 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3447) BLACT_WH PF17778.1 PRP85153.1 - 0.093 12.7 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain F-box-like PF12937.7 PRP85153.1 - 0.14 12.1 1.3 0.28 11.1 1.3 1.5 1 0 0 1 1 1 0 F-box-like zf-C3HC4_2 PF13923.6 PRP85156.1 - 3.4e-08 33.2 11.7 3.4e-08 33.2 11.7 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP85156.1 - 8.1e-08 32.0 11.9 8.1e-08 32.0 11.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP85156.1 - 3.3e-06 27.3 11.7 3.3e-06 27.3 11.7 2.5 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PRP85156.1 - 5e-05 23.2 10.5 0.00017 21.5 10.5 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PRP85156.1 - 6.5e-05 22.7 13.8 6.5e-05 22.7 13.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP85156.1 - 0.00048 20.1 9.9 0.00048 20.1 9.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PRP85156.1 - 0.0016 18.5 9.5 0.005 17.0 9.5 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PRP85156.1 - 0.0046 17.2 6.2 0.0046 17.2 6.2 2.6 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 PRP85156.1 - 0.0097 15.7 6.7 0.0097 15.7 6.7 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit RAWUL PF16207.5 PRP85156.1 - 0.034 14.8 0.2 0.1 13.3 0.0 1.9 2 0 0 2 2 2 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_6 PF14835.6 PRP85156.1 - 0.093 12.6 11.2 0.078 12.9 8.0 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PRP85156.1 - 0.83 9.5 10.9 2.8 7.8 10.9 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_5 PF17121.5 PRP85156.1 - 7.1 6.6 11.0 26 4.8 9.1 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rotamase_3 PF13616.6 PRP85157.1 - 1.3e-20 74.0 0.0 2.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 PRP85157.1 - 2.9e-16 60.2 0.0 7.7e-16 58.9 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 PRP85157.1 - 0.00016 22.5 0.0 0.00025 21.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain FAD_binding_3 PF01494.19 PRP85158.1 - 7.4e-13 48.5 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 PRP85158.1 - 0.011 15.9 0.1 0.029 14.6 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP85158.1 - 0.052 13.1 0.6 0.15 11.6 0.1 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PRP85158.1 - 0.067 12.3 0.2 0.094 11.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 PRP85158.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase C2 PF00168.30 PRP85159.1 - 3e-24 85.3 0.1 3e-24 85.3 0.1 1.7 2 0 0 2 2 2 1 C2 domain Homeodomain PF00046.29 PRP85160.1 - 2.5e-16 59.3 3.3 3.4e-16 58.8 3.3 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP85160.1 - 8.4e-05 22.4 0.1 0.00015 21.6 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Terminase_5 PF06056.12 PRP85160.1 - 0.057 13.3 0.2 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) McrBC PF10117.9 PRP85161.1 - 4.4e-46 157.5 0.5 5.8e-46 157.1 0.5 1.1 1 0 0 1 1 1 1 McrBC 5-methylcytosine restriction system component Pkinase_Tyr PF07714.17 PRP85162.1 - 1.1e-33 116.7 2.3 2.3e-33 115.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85162.1 - 1.8e-22 80.0 2.6 3.3e-22 79.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain PI-PLC-Y PF00387.19 PRP85162.1 - 0.25 11.7 2.7 0.43 10.9 2.0 1.8 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain MMPL PF03176.15 PRP85162.1 - 0.81 8.5 4.2 1.3 7.9 4.2 1.2 1 0 0 1 1 1 0 MMPL family SAM_1 PF00536.30 PRP85163.1 - 3.3e-14 53.1 0.0 6.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP85163.1 - 1.5e-08 34.6 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) 23S_rRNA_IVP PF05635.11 PRP85163.1 - 0.069 13.5 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein DUF1996 PF09362.10 PRP85164.1 - 1.7e-70 237.7 2.7 2.4e-70 237.2 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PAS_2 PF08446.11 PRP85165.1 - 0.15 12.7 0.0 0.32 11.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold lci PF12197.8 PRP85165.1 - 0.15 11.9 1.2 1.3 8.9 0.1 2.7 3 0 0 3 3 3 0 Bacillus cereus group antimicrobial protein Aa_trans PF01490.18 PRP85167.1 - 3.5e-15 55.6 22.1 1.6e-14 53.5 22.1 2.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 PRP85167.1 - 1.6e-05 24.2 17.0 1.6e-05 24.2 17.0 2.5 1 1 0 2 2 2 2 Tryptophan/tyrosine permease family ArAE_2 PF10334.9 PRP85172.1 - 1.1e-14 54.8 0.7 2.4e-14 53.7 0.7 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 PRP85172.1 - 1.2e-11 44.8 12.4 1.2e-11 44.8 12.4 3.7 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 PRP85172.1 - 4.3e-10 39.0 2.1 4.3e-10 39.0 2.1 3.1 3 1 0 3 3 3 2 Aluminium activated malate transporter ArAE_2_N PF10337.9 PRP85172.1 - 2e-09 37.0 4.9 2e-09 37.0 4.9 3.1 3 1 1 4 4 4 1 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 PRP85172.1 - 5e-05 22.1 10.6 5e-05 22.1 10.6 3.8 4 1 0 4 4 4 2 Fusaric acid resistance protein family Protocadherin PF08374.11 PRP85172.1 - 0.018 15.0 0.6 0.056 13.4 0.6 1.8 1 0 0 1 1 1 0 Protocadherin BTB_2 PF02214.22 PRP85173.1 - 3e-17 62.7 0.0 6.1e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Trigger_C PF05698.14 PRP85173.1 - 0.06 13.4 1.3 6.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus DLH PF01738.18 PRP85175.1 - 3.3e-20 72.6 0.7 4.1e-20 72.3 0.7 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family LCE PF14672.6 PRP85175.1 - 0.19 12.3 1.2 0.41 11.3 1.2 1.5 1 0 0 1 1 1 0 Late cornified envelope Glyco_hydro_16 PF00722.21 PRP85176.1 - 8.5e-20 70.9 0.4 1.4e-19 70.2 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 X8 PF07983.13 PRP85176.1 - 2e-12 47.6 1.9 4.9e-12 46.3 1.9 1.7 1 0 0 1 1 1 1 X8 domain Peroxidase_2 PF01328.17 PRP85177.1 - 4.4e-54 183.9 0.0 6.1e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 UCR_TM PF02921.14 PRP85177.1 - 0.09 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region FANCI_S4 PF14678.6 PRP85177.1 - 0.23 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 4 HALZ PF02183.18 PRP85180.1 - 0.21 11.8 0.1 0.21 11.8 0.1 8.4 9 0 0 9 9 9 0 Homeobox associated leucine zipper LINES_C PF14695.6 PRP85180.1 - 6.6 6.2 5.9 3.6 7.1 0.8 3.3 3 0 0 3 3 3 0 Lines C-terminus Insulin_TMD PF17870.1 PRP85181.1 - 0.051 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Conotoxin PF02950.17 PRP85183.1 - 0.037 15.0 0.8 0.067 14.2 0.8 1.5 1 0 0 1 1 1 0 Conotoxin Rad21_Rec8_N PF04825.13 PRP85184.1 - 2.8e-38 130.4 0.3 4.4e-38 129.8 0.3 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 PRP85184.1 - 7.5e-14 50.8 0.1 1.4e-12 46.6 0.0 2.3 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 PRP85184.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Abhydrolase_1 PF00561.20 PRP85186.1 - 1.8e-07 31.1 0.0 1.8e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP85186.1 - 5.5e-07 29.1 0.0 6.6e-05 22.3 0.0 3.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 HAND PF09110.11 PRP85186.1 - 0.33 11.7 4.6 1.1 10.1 0.1 2.3 2 0 0 2 2 2 0 HAND polyprenyl_synt PF00348.17 PRP85189.1 - 5.4e-62 209.2 0.0 7.8e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase DUF829 PF05705.14 PRP85190.1 - 5e-31 108.4 0.1 6.1e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 PRP85190.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF1533 PF07550.11 PRP85190.1 - 0.03 14.2 0.0 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) CvfB_WH PF17783.1 PRP85190.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 CvfB-like winged helix domain SH3_1 PF00018.28 PRP85192.1 - 9.2e-10 38.0 0.1 2e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP85192.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP85192.1 - 1.3e-07 31.2 0.0 3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain T3SSipB PF16535.5 PRP85192.1 - 0.0028 18.2 12.9 0.0028 18.2 12.9 4.8 1 1 2 4 4 4 1 Type III cell invasion protein SipB SOGA PF11365.8 PRP85192.1 - 0.023 15.8 2.5 0.023 15.8 2.5 8.5 2 1 6 9 9 9 0 Protein SOGA MDH PF02315.16 PRP85192.1 - 0.85 9.7 4.6 5.4 7.1 3.3 3.2 1 1 0 1 1 1 0 Methanol dehydrogenase beta subunit TFIIB PF00382.19 PRP85193.1 - 6.6e-10 38.9 0.1 1.2e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Sina PF03145.16 PRP85193.1 - 0.00036 20.5 1.0 0.00093 19.2 1.0 1.7 1 0 0 1 1 1 1 Seven in absentia protein family BRF1 PF07741.13 PRP85193.1 - 0.001 19.4 5.4 0.001 19.4 5.4 2.4 2 1 0 2 2 2 1 Brf1-like TBP-binding domain Dysbindin PF04440.16 PRP85193.1 - 0.034 14.3 0.2 0.13 12.5 0.2 1.9 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) HSV_VP16_C PF12149.8 PRP85193.1 - 0.22 11.6 1.3 0.46 10.6 1.3 1.5 1 0 0 1 1 1 0 Herpes simplex virus virion protein 16 C terminal Hydrolase_4 PF12146.8 PRP85194.1 - 3.9e-16 59.0 0.0 2.3e-10 40.1 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP85194.1 - 1.1e-15 58.0 0.0 1.6e-09 37.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold UPF0227 PF05728.12 PRP85194.1 - 5.9e-11 42.6 0.0 9.6e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.21 PRP85194.1 - 4.8e-07 29.5 0.2 2e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 PRP85194.1 - 7.7e-07 29.1 0.3 6.6e-05 22.8 0.1 2.6 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 PRP85194.1 - 1.2e-05 25.0 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 PRP85194.1 - 2.1e-05 24.5 0.1 5.7e-05 23.1 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 PRP85194.1 - 3.2e-05 23.6 0.0 7.7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 PRP85194.1 - 0.00028 21.6 0.0 0.0011 19.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 PRP85194.1 - 0.00041 20.1 0.5 0.018 14.8 0.0 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family TauE PF01925.19 PRP85194.1 - 0.00094 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE LIP PF03583.14 PRP85194.1 - 0.0043 16.4 0.1 0.054 12.8 0.0 2.0 2 0 0 2 2 2 1 Secretory lipase Ndr PF03096.14 PRP85194.1 - 0.0098 14.6 0.0 0.026 13.2 0.0 1.7 2 0 0 2 2 2 1 Ndr family DUF2920 PF11144.8 PRP85194.1 - 0.015 14.5 0.1 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Esterase PF00756.20 PRP85194.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 PRP85194.1 - 0.016 14.8 0.1 0.78 9.3 0.0 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Palm_thioest PF02089.15 PRP85194.1 - 0.023 14.5 0.0 0.37 10.6 0.0 2.1 2 0 0 2 2 2 0 Palmitoyl protein thioesterase SoxZ PF08770.11 PRP85194.1 - 0.027 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ DLH PF01738.18 PRP85194.1 - 0.05 13.1 0.1 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family SPG48 PF14764.6 PRP85195.1 - 0.00033 21.1 0.1 0.001 19.5 0.0 2.0 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking VF530 PF09905.9 PRP85195.1 - 0.092 12.9 0.0 5.4 7.3 0.0 2.5 2 0 0 2 2 2 0 DNA-binding protein VF530 Pkinase_Tyr PF07714.17 PRP85196.1 - 2.8e-73 246.4 0.1 6.1e-73 245.3 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85196.1 - 2.1e-49 168.3 0.0 6.5e-49 166.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP85196.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TFIID-31kDa PF02291.15 PRP85196.1 - 0.014 15.5 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TPALS PF18178.1 PRP85196.1 - 0.043 13.3 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Pkinase_fungal PF17667.1 PRP85196.1 - 0.062 12.1 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PRP85196.1 - 0.081 11.9 0.5 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain APP_amyloid PF10515.9 PRP85196.1 - 0.22 12.0 1.7 1 9.9 1.7 2.2 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus Pkinase_Tyr PF07714.17 PRP85197.1 - 3e-72 243.0 0.3 1.1e-71 241.2 0.3 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85197.1 - 1.2e-49 169.1 0.1 1.9e-49 168.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP85197.1 - 2.7e-40 135.9 76.1 6.6e-10 38.6 0.8 13.9 10 3 2 12 12 12 8 Leucine rich repeat LRR_4 PF12799.7 PRP85197.1 - 2.7e-30 103.9 91.5 2.4e-08 34.1 0.4 17.4 10 8 10 20 20 20 12 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP85197.1 - 4.7e-11 41.8 70.3 0.59 10.3 0.1 20.5 23 0 0 23 23 21 5 Leucine Rich repeat LRR_1 PF00560.33 PRP85197.1 - 1.3e-08 34.2 69.2 0.12 13.0 0.2 21.7 24 3 0 24 24 20 2 Leucine Rich Repeat Kdo PF06293.14 PRP85197.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM154 PF15102.6 PRP85197.1 - 0.0056 16.6 0.5 0.013 15.4 0.5 1.5 1 0 0 1 1 1 1 TMEM154 protein family Neurensin PF14927.6 PRP85197.1 - 0.014 15.1 0.5 0.049 13.3 0.1 2.1 2 0 0 2 2 2 0 Neurensin Stevor PF17410.2 PRP85197.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Pkinase_fungal PF17667.1 PRP85197.1 - 0.029 13.2 0.2 0.044 12.6 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase EphA2_TM PF14575.6 PRP85197.1 - 0.034 15.0 0.6 0.072 14.0 0.6 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4448 PF14610.6 PRP85197.1 - 0.053 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1453 PF07301.11 PRP85197.1 - 0.059 13.4 1.4 0.11 12.5 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) Kinase-like PF14531.6 PRP85197.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SKG6 PF08693.10 PRP85197.1 - 0.072 12.5 7.0 0.14 11.6 7.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M56 PF05569.11 PRP85197.1 - 0.083 12.1 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 LRRNT_2 PF08263.12 PRP85197.1 - 0.09 13.1 1.9 0.33 11.3 1.9 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Haspin_kinase PF12330.8 PRP85197.1 - 0.11 11.4 0.2 0.25 10.2 0.2 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DUF3377 PF11857.8 PRP85197.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Shisa PF13908.6 PRP85197.1 - 0.17 12.1 0.3 0.43 10.8 0.3 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MMACHC PF16690.5 PRP85198.1 - 3.2e-19 69.4 0.0 6e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family Peptidase_C15 PF01470.17 PRP85199.1 - 1.7e-10 41.4 0.0 2.6e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 Pyroglutamyl peptidase Pkinase_Tyr PF07714.17 PRP85200.1 - 8.3e-62 208.8 0.1 1.4e-61 208.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85200.1 - 1.2e-39 136.3 0.0 2.3e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP85200.1 - 5e-31 106.3 74.1 7.6e-07 28.8 1.7 13.7 11 3 4 15 15 15 11 Leucine rich repeat LRR_4 PF12799.7 PRP85200.1 - 6.5e-31 105.9 84.5 3.3e-07 30.5 1.1 14.9 11 3 5 16 16 16 14 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP85200.1 - 4e-10 38.9 69.1 0.69 10.1 0.0 19.4 21 0 0 21 21 21 4 Leucine Rich repeat LRR_1 PF00560.33 PRP85200.1 - 4.1e-07 29.7 76.3 2.7 8.9 0.3 20.3 21 2 0 21 21 21 4 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP85200.1 - 0.0018 18.5 0.7 0.0047 17.2 0.7 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain TFIID-31kDa PF02291.15 PRP85200.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LRR_9 PF14580.6 PRP85200.1 - 0.14 11.6 10.7 4.5 6.7 1.3 5.2 4 1 0 4 4 4 0 Leucine-rich repeat LRR_2 PF07723.13 PRP85200.1 - 1.2 9.9 8.4 54 4.7 0.0 6.6 6 0 0 6 6 6 0 Leucine Rich Repeat Rad51 PF08423.11 PRP85201.1 - 3.4e-124 413.2 0.1 4.8e-124 412.7 0.1 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PRP85201.1 - 1e-09 38.3 0.3 2.3e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 PRP85201.1 - 1.5e-09 37.7 0.1 2.3e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 PRP85201.1 - 6.7e-07 29.8 1.5 6.7e-07 29.8 1.5 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 PRP85201.1 - 1.9e-05 24.1 2.3 0.00035 20.0 2.3 2.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 PRP85201.1 - 0.067 12.5 0.1 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Pkinase PF00069.25 PRP85203.1 - 5.4e-48 163.6 0.0 2e-47 161.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85203.1 - 8.3e-23 81.0 0.0 1.6e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP85203.1 - 1.5e-14 54.5 0.8 7.3e-08 32.6 0.0 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family EcKinase PF02958.20 PRP85203.1 - 1.6e-14 54.0 0.2 2e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 PRP85203.1 - 5.3e-09 35.4 0.3 1e-08 34.5 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Kinase-like PF14531.6 PRP85203.1 - 7.4e-09 35.3 0.0 6.7e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP85203.1 - 5.4e-06 25.9 0.0 8.4e-05 22.0 0.1 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP85203.1 - 7.2e-05 22.5 0.0 0.042 13.4 0.0 2.6 3 0 0 3 3 3 2 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PRP85203.1 - 0.00087 18.3 0.2 0.0036 16.3 0.2 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PRP85203.1 - 0.035 13.2 0.0 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Insulin_TMD PF17870.1 PRP85205.1 - 0.018 15.1 0.2 0.041 14.0 0.2 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment zf-piccolo PF05715.13 PRP85206.1 - 0.02 15.1 1.3 0.032 14.4 1.3 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger Pkinase_Tyr PF07714.17 PRP85207.1 - 6e-54 183.0 0.0 1.2e-53 182.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP85207.1 - 6.8e-38 128.3 87.1 6.5e-07 29.0 0.1 12.9 9 2 4 14 14 14 12 Leucine rich repeat Pkinase PF00069.25 PRP85207.1 - 5.3e-36 124.3 0.0 8e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP85207.1 - 1.2e-26 92.3 92.4 1.6e-05 25.1 0.3 15.7 8 3 12 20 20 20 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP85207.1 - 0.0096 16.3 75.3 0.48 11.2 0.0 18.9 21 1 0 21 21 21 3 Leucine Rich Repeat SKG6 PF08693.10 PRP85207.1 - 0.011 15.1 5.7 0.024 14.1 5.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 PRP85207.1 - 0.058 12.2 0.1 0.058 12.2 0.1 1.6 2 0 0 2 2 2 0 Amnionless LRRNT_2 PF08263.12 PRP85207.1 - 0.36 11.2 3.6 0.29 11.5 1.2 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PRP85207.1 - 0.64 10.2 56.0 1.7 8.9 0.2 15.0 16 0 0 16 16 16 0 Leucine Rich repeat Adeno_E3_CR2 PF02439.15 PRP85207.1 - 1.2 9.0 4.4 2.2 8.1 4.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 p450 PF00067.22 PRP85208.1 - 2.9e-70 237.3 0.1 4e-70 236.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 PRP85208.1 - 1.2e-30 106.7 0.0 2.4e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PRP85208.1 - 7.7e-20 71.6 0.4 4.5e-19 69.1 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 PRP85208.1 - 3.7e-14 53.3 0.1 4e-13 50.0 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF806 PF05657.11 PRP85208.1 - 0.052 14.0 0.1 0.14 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF806) Eco57I PF07669.11 PRP85208.1 - 0.052 14.0 0.0 0.32 11.5 0.0 2.3 2 0 0 2 2 2 0 Eco57I restriction-modification methylase zf-MYND PF01753.18 PRP85209.1 - 1.9e-05 24.6 8.1 3.8e-05 23.7 8.1 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 PRP85209.1 - 0.43 10.9 4.5 1.5 9.2 4.5 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding G8 PF10162.9 PRP85210.1 - 0.0093 16.0 0.2 0.034 14.2 0.1 2.0 2 0 0 2 2 2 1 G8 domain Insulin_TMD PF17870.1 PRP85210.1 - 0.053 13.6 0.8 0.14 12.3 0.8 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF4097 PF13349.6 PRP85210.1 - 2.3 7.5 7.4 18 4.6 2.9 2.4 1 1 0 2 2 2 0 Putative adhesin Proteasome PF00227.26 PRP85212.1 - 1.1e-60 204.4 0.1 1.4e-60 204.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PRP85212.1 - 0.015 14.9 0.2 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Gln-synt_C PF00120.24 PRP85213.1 - 1e-97 327.3 0.0 1.3e-97 326.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain COPIIcoated_ERV PF07970.12 PRP85214.1 - 1.5e-47 162.3 0.6 2.5e-47 161.6 0.6 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter RhoGAP PF00620.27 PRP85214.1 - 5.6e-41 139.9 0.0 1.2e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RNA_pol_L_2 PF13656.6 PRP85214.1 - 5.9e-24 83.6 0.1 3.6e-23 81.1 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ERGIC_N PF13850.6 PRP85214.1 - 1.5e-12 47.7 0.0 3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RPEL PF02755.15 PRP85214.1 - 1.1e-08 34.5 3.9 0.0022 17.6 1.3 2.5 2 0 0 2 2 2 2 RPEL repeat SH3_1 PF00018.28 PRP85214.1 - 4.9e-08 32.5 0.3 1e-07 31.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain RNA_pol_L PF01193.24 PRP85214.1 - 7.2e-08 31.7 0.0 1.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SH3_9 PF14604.6 PRP85214.1 - 2.8e-06 27.1 0.4 5.4e-06 26.2 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP85214.1 - 0.0038 16.9 0.1 0.0097 15.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain TPR_12 PF13424.6 PRP85215.1 - 1.6e-17 63.6 7.0 4.5e-09 36.5 0.0 6.1 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP85215.1 - 8e-11 42.3 5.4 0.0039 17.7 0.0 5.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85215.1 - 3.8e-10 39.1 14.7 0.13 12.5 0.1 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 PRP85215.1 - 1.6e-08 34.1 1.9 0.19 11.6 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP85215.1 - 4e-08 32.7 12.7 0.019 14.8 0.3 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP85215.1 - 1.6e-06 27.8 0.2 0.0046 16.4 0.1 2.8 2 1 1 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 PRP85215.1 - 5e-05 23.2 16.1 0.027 14.7 0.3 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 PRP85215.1 - 7.5e-05 22.3 2.3 7.5e-05 22.3 2.3 3.3 3 1 1 4 4 4 1 Coatomer epsilon subunit TPR_7 PF13176.6 PRP85215.1 - 0.00011 21.9 14.5 0.029 14.4 0.0 6.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP85215.1 - 0.0012 19.5 0.1 54 5.0 0.0 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP85215.1 - 0.0012 19.0 10.0 0.68 10.2 3.0 4.6 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 PRP85215.1 - 0.0029 17.7 0.8 6.9 7.2 0.0 4.9 5 0 0 5 5 5 1 PPR repeat CAMSAP_CC1 PF17095.5 PRP85215.1 - 0.0031 17.3 4.5 0.0083 16.0 4.5 1.7 1 0 0 1 1 1 1 Spectrin-binding region of Ca2+-Calmodulin SHNi-TPR PF10516.9 PRP85215.1 - 0.0087 15.5 0.0 0.044 13.2 0.0 2.3 1 1 0 1 1 1 1 SHNi-TPR ChAPs PF09295.10 PRP85215.1 - 0.009 15.1 1.6 0.016 14.2 1.2 1.6 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_16 PF13432.6 PRP85215.1 - 0.024 15.3 0.3 64 4.3 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 PRP85215.1 - 0.062 13.0 4.7 2.6 7.8 0.2 4.1 5 1 1 6 6 6 0 TPR repeat RseA_C PF03873.13 PRP85215.1 - 0.24 11.7 2.3 0.65 10.3 0.3 2.4 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain MIT PF04212.18 PRP85215.1 - 0.58 10.3 10.3 0.14 12.3 0.4 3.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Sulfate_transp PF00916.20 PRP85219.1 - 5.5e-92 308.5 19.9 8.3e-92 307.9 19.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PRP85219.1 - 1.2e-15 57.2 0.1 2.2e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 PRP85219.1 - 0.053 13.9 13.1 0.026 14.9 4.4 2.8 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 PRP85219.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 STAS domain SPO22 PF08631.10 PRP85220.1 - 4.3e-19 69.1 19.1 5.7e-18 65.4 2.4 4.5 5 1 1 6 6 6 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 PRP85220.1 - 1.6e-09 37.9 0.4 0.14 12.5 0.1 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85220.1 - 2.7e-08 33.3 0.2 0.38 11.0 0.0 7.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP85220.1 - 1.2e-05 24.9 0.3 0.44 10.4 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP85220.1 - 1.6e-05 24.7 3.1 0.58 10.5 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP85220.1 - 9.3e-05 22.0 4.9 0.27 10.6 0.1 3.3 3 0 0 3 3 3 3 MalT-like TPR region TPR_19 PF14559.6 PRP85220.1 - 0.00019 21.9 0.2 0.89 10.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP85220.1 - 0.00027 21.5 2.7 0.85 10.6 0.0 4.5 5 1 1 6 6 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP85220.1 - 0.006 16.8 0.1 2.1 8.6 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PRP85220.1 - 0.0081 16.8 0.0 2.1 9.1 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat PrkA PF06798.12 PRP85220.1 - 0.045 13.4 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain MFS_1 PF07690.16 PRP85221.1 - 7.9e-33 113.8 30.2 7.9e-33 113.8 30.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4337 PF14235.6 PRP85221.1 - 0.23 11.6 0.0 0.56 10.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Herpes_TK PF00693.18 PRP85221.1 - 0.32 10.2 0.6 0.61 9.3 0.0 1.7 2 0 0 2 2 2 0 Thymidine kinase from herpesvirus GvpL_GvpF PF06386.11 PRP85221.1 - 0.42 10.5 3.6 0.63 9.9 3.6 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Rrp15p PF07890.12 PRP85221.1 - 0.44 10.9 10.8 0.7 10.2 10.8 1.2 1 0 0 1 1 1 0 Rrp15p NPR3 PF03666.13 PRP85221.1 - 1.4 7.6 4.5 1.9 7.1 4.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 OATP PF03137.20 PRP85221.1 - 2.9 6.1 12.7 1.6 6.9 0.5 3.8 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S9 PF00326.21 PRP85222.1 - 6.6e-34 117.2 0.1 1.6e-33 116.0 0.1 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family TPR_12 PF13424.6 PRP85222.1 - 1.9e-26 92.2 4.1 6e-07 29.7 0.0 5.4 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85222.1 - 1.2e-16 59.4 1.0 0.00036 20.4 0.2 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP85222.1 - 2.5e-11 42.9 4.7 0.56 10.6 0.1 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP85222.1 - 3.6e-10 39.2 10.7 0.0043 16.8 0.3 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP85222.1 - 1.6e-07 31.0 0.0 0.00083 18.8 0.0 2.2 2 0 0 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 PRP85222.1 - 1.9e-07 31.3 0.0 0.1 13.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP85222.1 - 2.3e-07 30.4 1.5 0.64 10.2 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP85222.1 - 8.9e-07 29.5 0.2 2 9.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP85222.1 - 3.3e-06 27.5 0.0 0.1 13.1 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Hydrolase_4 PF12146.8 PRP85222.1 - 7.5e-06 25.4 0.2 0.024 13.9 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 SNAP PF14938.6 PRP85222.1 - 1.6e-05 24.5 0.2 0.019 14.4 0.0 3.0 2 1 1 3 3 3 2 Soluble NSF attachment protein, SNAP DLH PF01738.18 PRP85222.1 - 4.9e-05 23.0 0.1 0.00029 20.5 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 PRP85222.1 - 5.9e-05 22.8 0.6 0.046 13.4 0.3 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold TPR_11 PF13414.6 PRP85222.1 - 0.00025 20.7 0.4 2.9 7.6 0.0 3.8 3 0 0 3 3 3 2 TPR repeat COesterase PF00135.28 PRP85222.1 - 0.00027 19.9 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family C1_1 PF00130.22 PRP85222.1 - 0.00062 19.6 11.7 0.0015 18.4 11.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) TPR_6 PF13174.6 PRP85222.1 - 0.00064 20.2 2.2 0.43 11.3 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 PRP85222.1 - 0.00069 19.4 4.0 5.9 6.9 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat FSH1 PF03959.13 PRP85222.1 - 0.0008 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) TPR_4 PF07721.14 PRP85222.1 - 0.0015 19.0 0.1 1.5 9.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP85222.1 - 0.0066 16.6 6.1 0.089 13.0 0.4 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 PRP85222.1 - 0.0093 16.0 0.4 10 6.2 0.2 3.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 PRP85222.1 - 0.059 13.1 1.7 6.4 6.4 0.1 3.5 2 2 2 4 4 4 0 26S proteasome subunit RPN7 DUF5062 PF16691.5 PRP85223.1 - 0.036 14.2 0.0 0.059 13.5 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5062) Ank_2 PF12796.7 PRP85224.1 - 5e-17 62.3 0.0 1e-07 32.4 0.0 5.1 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85224.1 - 1.1e-13 51.4 7.6 0.00061 20.3 0.1 8.4 2 1 8 10 10 10 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85224.1 - 6.6e-11 42.2 2.5 0.17 12.3 0.0 8.0 5 3 5 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85224.1 - 1.4e-08 34.3 0.0 0.0022 18.4 0.0 7.3 8 1 1 9 9 9 1 Ankyrin repeat F-box-like PF12937.7 PRP85224.1 - 3.1e-05 23.8 0.4 8.3e-05 22.4 0.4 1.7 1 0 0 1 1 1 1 F-box-like PilZ_2 PF16823.5 PRP85224.1 - 0.18 12.0 0.5 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 Atypical PilZ domain, cyclic di-GMP receptor APH PF01636.23 PRP85225.1 - 4.6e-42 144.6 0.0 6.5e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PRP85225.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 PRP85225.1 - 0.03 13.9 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.11 PRP85225.1 - 0.2 10.5 0.0 6.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) F-box-like PF12937.7 PRP85226.1 - 1.2e-07 31.5 0.1 8.5e-07 28.8 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP85226.1 - 5.6e-07 29.3 2.5 9e-06 25.4 0.1 3.1 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 PRP85226.1 - 0.0017 18.2 0.4 0.041 13.7 0.0 2.4 2 0 0 2 2 2 1 F-box CTD_bind PF04818.13 PRP85226.1 - 0.0094 16.8 0.6 0.029 15.2 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Ank_3 PF13606.6 PRP85226.1 - 0.01 16.2 0.0 0.15 12.7 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 PRP85226.1 - 0.037 14.6 0.0 0.099 13.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 PRP85226.1 - 0.061 13.8 0.0 0.33 11.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat zf-RING_2 PF13639.6 PRP85227.1 - 1.4e-11 44.5 2.2 2.6e-11 43.7 2.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP85227.1 - 8.3e-09 35.2 2.0 1.5e-08 34.3 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP85227.1 - 2e-08 33.8 0.9 4.3e-08 32.8 0.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PRP85227.1 - 1.9e-07 30.8 1.4 3.4e-07 30.0 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP85227.1 - 4.4e-07 30.1 1.1 1.2e-06 28.7 1.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP85227.1 - 7.4e-05 22.7 1.8 0.00016 21.6 1.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP85227.1 - 0.001 19.0 1.6 0.0018 18.2 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PRP85227.1 - 0.0031 17.5 0.2 0.0065 16.5 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PRP85227.1 - 0.014 15.2 0.9 0.023 14.5 0.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PRP85227.1 - 0.046 13.3 1.4 0.088 12.4 1.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PRP85227.1 - 0.049 13.8 2.2 0.11 12.7 2.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 PRP85227.1 - 0.083 13.1 1.7 0.2 11.8 1.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 PRP85227.1 - 0.14 12.3 1.7 0.35 11.0 1.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 PRP85227.1 - 0.41 11.0 1.5 0.71 10.2 1.5 1.3 1 0 0 1 1 1 0 RING-like domain UPF0061 PF02696.14 PRP85228.1 - 3.7e-120 401.9 0.0 5.4e-120 401.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TBCC_N PF16752.5 PRP85228.1 - 0.017 15.5 0.7 0.057 13.9 0.7 1.9 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain MFS_1 PF07690.16 PRP85230.1 - 1.3e-30 106.5 46.1 2.3e-25 89.3 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP85230.1 - 2.8e-13 49.5 2.9 2.8e-13 49.5 2.9 3.0 2 1 1 4 4 4 2 Sugar (and other) transporter Cys_Met_Meta_PP PF01053.20 PRP85231.1 - 2.5e-134 447.6 0.0 3.1e-134 447.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 PRP85231.1 - 0.00028 20.2 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 PRP85231.1 - 0.001 17.7 0.1 0.0031 16.1 0.1 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 PRP85231.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PRP85231.1 - 0.12 11.6 0.1 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF1329 PF07044.11 PRP85232.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1329) SH3BGR PF04908.15 PRP85232.1 - 0.093 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein A_deamin PF02137.18 PRP85233.1 - 4.7e-73 246.5 0.0 5.9e-73 246.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain RUN PF02759.19 PRP85234.1 - 2.1e-15 56.9 1.5 5.7e-15 55.5 0.2 2.1 2 0 0 2 2 2 1 RUN domain GAS PF13851.6 PRP85234.1 - 0.0014 18.0 2.6 0.0014 18.0 2.6 2.6 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 PRP85234.1 - 0.011 15.8 3.9 0.011 15.8 3.9 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus HisKA_3 PF07730.13 PRP85234.1 - 0.052 14.1 0.4 5.3 7.6 0.9 3.0 2 0 0 2 2 2 0 Histidine kinase DUF4248 PF14053.6 PRP85234.1 - 0.1 12.7 0.5 8.7 6.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) AbiEi_1 PF09407.10 PRP85234.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain ProSAAS PF07259.12 PRP85234.1 - 0.14 12.1 2.7 4.6 7.2 0.0 3.0 3 0 0 3 3 3 0 ProSAAS precursor PEP-utilisers_N PF05524.13 PRP85234.1 - 0.36 11.0 3.9 0.2 11.9 0.6 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Laminin_II PF06009.12 PRP85234.1 - 0.56 10.2 6.5 0.52 10.3 0.9 3.2 2 1 0 2 2 2 0 Laminin Domain II DUF4398 PF14346.6 PRP85234.1 - 0.57 10.8 5.2 0.21 12.2 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4398) PRKG1_interact PF15898.5 PRP85234.1 - 1.3 10.0 18.3 0.16 12.9 2.9 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1664 PF07889.12 PRP85234.1 - 2.5 8.2 8.7 0.23 11.5 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 PRP85234.1 - 5.6 5.8 6.0 4 6.2 3.3 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein BRE1 PF08647.11 PRP85234.1 - 8.8 6.5 15.8 0.16 12.0 3.9 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF4064 PF13273.6 PRP85235.1 - 0.00013 22.2 1.9 0.00023 21.4 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) PAN_2 PF08276.11 PRP85235.1 - 0.0065 16.6 1.5 0.02 15.0 1.5 1.8 1 0 0 1 1 1 1 PAN-like domain DUF3672 PF12421.8 PRP85235.1 - 0.0083 16.0 1.6 0.054 13.4 0.0 3.1 2 0 0 2 2 2 1 Fibronectin type III protein Podoplanin PF05808.11 PRP85235.1 - 0.015 15.4 0.2 0.015 15.4 0.2 2.5 3 0 0 3 3 3 0 Podoplanin PAN_4 PF14295.6 PRP85235.1 - 1.6 8.7 4.3 6 6.9 3.1 2.6 2 0 0 2 2 2 0 PAN domain GPS PF01825.21 PRP85235.1 - 2.1 8.9 10.3 0.091 13.3 3.2 2.6 3 0 0 3 3 3 0 GPCR proteolysis site, GPS, motif PH PF00169.29 PRP85236.1 - 7.9e-14 52.0 0.1 2.2e-13 50.6 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP85236.1 - 2e-05 25.0 0.3 6.6e-05 23.3 0.3 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PRP85236.1 - 0.00034 20.8 0.8 0.12 12.7 0.1 3.3 2 1 1 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 PRP85236.1 - 0.00075 19.6 0.2 0.44 10.7 0.1 3.0 2 1 0 2 2 2 1 PH domain WH1 PF00568.23 PRP85236.1 - 0.0079 16.1 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 PRP85236.1 - 0.062 13.7 0.2 0.26 11.7 0.0 2.3 2 0 0 2 2 2 0 P21-Rho-binding domain DUF3572 PF12096.8 PRP85236.1 - 0.091 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) DCP1 PF06058.13 PRP85236.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Dcp1-like decapping family HECT PF00632.25 PRP85237.1 - 5.5e-71 239.6 0.0 8.8e-71 238.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_4 PF13637.6 PRP85237.1 - 1.9e-33 114.4 3.5 1.4e-10 41.5 0.0 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP85237.1 - 1.6e-31 108.7 0.2 1.1e-12 48.3 0.0 4.8 3 1 3 6 6 6 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP85237.1 - 3.7e-26 90.8 0.5 2.4e-09 37.3 0.0 5.7 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85237.1 - 2.7e-23 79.5 0.9 4.1e-05 23.7 0.1 8.0 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 PRP85237.1 - 2e-21 75.4 5.1 8.9e-10 38.6 0.3 5.7 5 0 0 5 5 5 3 Ankyrin repeat SPT6_acidic PF14632.6 PRP85237.1 - 0.23 12.1 19.8 0.11 13.1 10.5 2.9 1 1 1 2 2 2 0 Acidic N-terminal SPT6 GST_C_3 PF14497.6 PRP85238.1 - 6.3e-14 52.0 0.2 3.5e-13 49.6 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP85238.1 - 5.8e-11 42.6 0.0 3.5e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Myb_DNA-binding PF00249.31 PRP85238.1 - 3.2e-08 33.7 0.3 0.00041 20.5 0.0 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain GST_N_3 PF13417.6 PRP85238.1 - 5.6e-07 29.9 0.0 2.7e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP85238.1 - 1e-05 25.8 0.0 0.00037 20.8 0.0 3.1 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP85238.1 - 1.5e-05 25.1 0.0 4.4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Myb_DNA-bind_6 PF13921.6 PRP85238.1 - 5.5e-05 23.3 3.9 0.038 14.2 0.1 4.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Pkinase PF00069.25 PRP85240.1 - 1.8e-70 237.3 0.0 2.4e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85240.1 - 1.7e-50 171.7 0.0 2.8e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP85240.1 - 6.5e-17 62.0 0.0 1.7e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 PH domain PBD PF00786.28 PRP85240.1 - 4.5e-13 49.3 0.0 1.2e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 PRP85240.1 - 0.00024 20.0 0.0 0.00046 19.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 PRP85240.1 - 0.00034 21.0 0.2 0.0014 19.1 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_17 PF18012.1 PRP85240.1 - 0.012 15.3 0.0 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 PH domain PH_8 PF15409.6 PRP85240.1 - 0.031 14.6 0.1 0.09 13.1 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain APH PF01636.23 PRP85240.1 - 0.072 13.0 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family CKS PF01111.19 PRP85242.1 - 4.9e-34 116.4 1.3 5.4e-34 116.3 1.3 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit GST_C_3 PF14497.6 PRP85243.1 - 1.5e-11 44.3 0.0 2.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP85243.1 - 6.5e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP85243.1 - 1.4e-06 28.7 0.0 3.3e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP85243.1 - 6.6e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP85243.1 - 0.00077 19.6 0.1 0.0012 19.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CH PF00307.31 PRP85244.1 - 5.5e-13 49.0 0.1 1e-12 48.2 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain GAS2 PF02187.17 PRP85244.1 - 1e-10 41.5 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SH3_9 PF14604.6 PRP85244.1 - 2.6e-10 40.0 0.0 3e-06 27.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 PRP85244.1 - 1.4e-07 31.0 0.2 0.0042 16.7 0.0 3.5 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 PRP85244.1 - 2.7e-07 30.2 0.0 0.002 17.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain CDC24 PF06395.11 PRP85244.1 - 0.0011 19.2 0.1 0.0021 18.3 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin CAMSAP_CH PF11971.8 PRP85244.1 - 0.02 14.7 0.2 0.062 13.1 0.1 1.9 2 0 0 2 2 2 0 CAMSAP CH domain PH PF00169.29 PRP85245.1 - 5.8e-06 26.8 0.5 1.9e-05 25.1 0.5 1.9 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.6 PRP85245.1 - 1.1e-05 25.2 0.1 4.3e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 PRP85245.1 - 1.4e-05 24.7 0.0 2.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP85245.1 - 0.028 14.0 0.1 0.17 11.5 0.0 2.1 2 0 0 2 2 2 0 SH3 domain DUF3729 PF12526.8 PRP85245.1 - 2.2 9.9 10.9 0.88 11.2 7.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) zf-U1 PF06220.12 PRP85246.1 - 4.6e-10 39.1 5.1 1.1e-09 37.9 5.1 1.7 1 0 0 1 1 1 1 U1 zinc finger OTT_1508_deam PF14441.6 PRP85246.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.8 1 0 0 1 1 1 0 OTT_1508-like deaminase zf-CCCH PF00642.24 PRP85246.1 - 0.087 12.8 0.6 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.8 PRP85246.1 - 0.52 10.7 2.7 1.8 8.9 2.7 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PhyH PF05721.13 PRP85247.1 - 0.0035 17.6 0.1 0.0055 17.0 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 PRP85247.1 - 0.034 15.1 0.0 0.059 14.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1479 PF07350.12 PRP85247.1 - 0.14 10.9 0.0 2.6 6.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1479) Bromodomain PF00439.25 PRP85248.1 - 3.7e-20 71.8 0.2 8.6e-20 70.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain RNase_H2-Ydr279 PF09468.10 PRP85248.1 - 0.8 9.9 5.7 0.17 12.0 0.7 2.4 3 1 0 3 3 3 0 Ydr279p protein family (RNase H2 complex component) wHTH domain ZapB PF06005.12 PRP85250.1 - 7.3e-05 23.1 4.4 7.3e-05 23.1 4.4 2.4 2 1 0 2 2 1 1 Cell division protein ZapB GAS PF13851.6 PRP85250.1 - 0.00036 20.0 3.9 0.00036 20.0 3.9 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 PRP85250.1 - 0.0018 18.4 4.6 0.0018 18.4 4.6 1.9 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 YabA PF06156.13 PRP85250.1 - 0.0037 17.9 0.1 0.0037 17.9 0.1 2.0 2 0 0 2 2 2 1 Initiation control protein YabA DivIC PF04977.15 PRP85250.1 - 0.0065 16.2 3.4 0.0065 16.2 3.4 2.3 2 0 0 2 2 2 1 Septum formation initiator Jnk-SapK_ap_N PF09744.9 PRP85250.1 - 0.022 15.0 0.9 0.022 15.0 0.9 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Tho2 PF11262.8 PRP85250.1 - 0.072 12.3 0.1 0.072 12.3 0.1 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 TSC22 PF01166.18 PRP85250.1 - 0.086 13.2 0.9 0.26 11.6 0.9 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family TolA_bind_tri PF16331.5 PRP85250.1 - 0.1 12.7 1.3 0.16 12.1 0.1 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation Herpes_UL6 PF01763.16 PRP85250.1 - 0.25 9.8 2.6 0.17 10.4 1.3 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like CCDC53 PF10152.9 PRP85250.1 - 0.29 11.6 0.2 0.29 11.6 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TMF_DNA_bd PF12329.8 PRP85250.1 - 0.31 11.1 21.8 0.07 13.1 9.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NYD-SP28_assoc PF14775.6 PRP85250.1 - 0.7 10.0 3.1 8 6.6 0.5 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain APG6_N PF17675.1 PRP85250.1 - 5.4 7.6 13.5 0.1 13.1 4.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region EspB PF05802.11 PRP85250.1 - 6.5 6.7 9.3 95 2.9 9.2 2.2 1 1 0 1 1 1 0 Enterobacterial EspB protein bZIP_1 PF00170.21 PRP85250.1 - 6.5 6.9 14.6 0.12 12.5 6.8 2.1 2 0 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 PRP85250.1 - 9.7 6.6 11.7 0.35 11.3 1.5 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.9 PRP85250.1 - 9.7 5.2 9.5 0.19 10.8 1.8 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 OB_NTP_bind PF07717.16 PRP85251.1 - 5.7e-22 77.9 0.1 1.2e-21 76.9 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PRP85251.1 - 6.8e-15 55.3 0.0 2.2e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PRP85251.1 - 4.3e-13 49.6 0.2 1.3e-12 48.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP85251.1 - 3.4e-07 30.2 0.0 7.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PRP85251.1 - 7.5e-05 23.0 0.2 0.00033 20.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PRP85251.1 - 0.00044 20.0 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP85251.1 - 0.0019 18.5 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PRP85251.1 - 0.016 14.3 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 PRP85251.1 - 0.04 13.4 0.3 0.83 9.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 PRP85251.1 - 0.048 14.2 0.0 0.78 10.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF2075 PF09848.9 PRP85251.1 - 0.098 11.9 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 PRP85251.1 - 0.17 11.5 0.7 2.9 7.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ADH_zinc_N PF00107.26 PRP85252.1 - 2.8e-16 59.7 0.1 6.7e-16 58.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP85252.1 - 1.6e-08 34.4 0.1 4.7e-08 32.9 0.1 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PRP85252.1 - 0.0053 17.8 0.0 0.01 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 PRP85252.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Ank_2 PF12796.7 PRP85253.1 - 1.7e-17 63.8 0.0 3.6e-08 33.9 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85253.1 - 4.6e-11 43.0 2.0 0.0027 18.2 0.0 4.9 2 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP85253.1 - 1.2e-10 41.4 5.1 0.54 10.8 0.0 7.4 5 2 1 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PRP85253.1 - 1.4e-07 31.6 0.3 1.8 9.0 0.0 6.4 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85253.1 - 1.2e-05 25.3 0.1 17 6.4 0.0 6.4 7 0 0 7 7 7 1 Ankyrin repeat F-box PF00646.33 PRP85253.1 - 0.047 13.6 0.6 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 F-box domain Rax2 PF12768.7 PRP85254.1 - 0.021 14.3 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Ras PF00071.22 PRP85257.1 - 8.6e-49 165.2 0.0 1.3e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP85257.1 - 2.7e-30 105.0 0.0 1.1e-29 103.1 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP85257.1 - 7.6e-11 41.8 0.0 9.9e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 PRP85257.1 - 0.00015 22.1 0.1 0.0037 17.6 0.1 2.3 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 PRP85257.1 - 0.0015 18.0 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP85257.1 - 0.0016 18.5 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 PRP85257.1 - 0.018 14.8 0.3 0.03 14.0 0.3 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 PRP85257.1 - 0.021 14.4 0.2 0.17 11.4 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 PRP85257.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 PRP85257.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 PRP85257.1 - 0.082 12.9 0.1 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PRP85257.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 PRP85257.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 PRP85257.1 - 0.12 11.5 1.7 1.1 8.4 0.1 2.3 2 1 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 PRP85257.1 - 0.14 12.0 0.1 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Bromodomain PF00439.25 PRP85259.1 - 9.3e-21 73.7 0.4 2.4e-20 72.4 0.4 1.8 1 0 0 1 1 1 1 Bromodomain PCAF_N PF06466.11 PRP85259.1 - 2.5e-18 66.6 6.4 3.2e-11 43.3 0.0 2.5 2 1 0 2 2 2 2 PCAF (P300/CBP-associated factor) N-terminal domain Acetyltransf_1 PF00583.25 PRP85259.1 - 6.3e-08 32.9 0.2 1.6e-07 31.6 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP85259.1 - 2e-07 31.0 0.2 5.1e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP85259.1 - 3.9e-05 24.0 0.5 9.2e-05 22.8 0.5 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_46 PF01374.18 PRP85260.1 - 5.5e-35 120.9 0.2 8.1e-35 120.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Chitin_bind_1 PF00187.19 PRP85260.1 - 2.5e-11 43.8 40.0 1.6e-06 28.5 20.7 3.4 3 0 0 3 3 3 2 Chitin recognition protein Dicty_CTDC PF00526.18 PRP85260.1 - 0.0094 15.8 15.2 0.18 11.7 1.6 3.6 3 0 0 3 3 3 2 Dictyostelium (slime mold) repeat Filament_head PF04732.14 PRP85260.1 - 5.1 8.0 20.7 2.8 8.9 9.7 2.8 3 0 0 3 3 3 0 Intermediate filament head (DNA binding) region Sacchrp_dh_NADP PF03435.18 PRP85266.1 - 1.3e-15 57.8 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF3368 PF11848.8 PRP85266.1 - 0.048 13.5 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Glyco_hydro_72 PF03198.14 PRP85267.1 - 1.1e-107 360.0 1.7 1.8e-107 359.3 1.7 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 PRP85267.1 - 9.7e-26 90.3 17.7 5.3e-15 55.9 7.7 2.8 2 0 0 2 2 2 2 X8 domain Glyco_hydro_2_C PF02836.17 PRP85267.1 - 8.6e-07 28.4 0.2 2e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 PRP85267.1 - 0.00017 21.1 0.2 0.00048 19.6 0.2 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RBD-FIP PF09457.10 PRP85269.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FIP domain DNase_II PF03265.15 PRP85270.1 - 3.2e-89 299.4 0.1 3.6e-89 299.2 0.1 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Homeodomain PF00046.29 PRP85271.1 - 0.027 14.3 0.2 6.3 6.7 0.0 2.9 2 0 0 2 2 2 0 Homeodomain HEPN_LA2681 PF18733.1 PRP85271.1 - 0.045 13.1 0.1 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 LA2681-like HEPN Cellulase PF00150.18 PRP85272.1 - 4.4e-39 134.6 1.0 4.4e-39 134.6 1.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 PRP85272.1 - 1.1e-10 41.3 9.3 1.1e-10 41.3 9.3 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF3510 PF12022.8 PRP85272.1 - 0.16 12.3 1.7 0.56 10.6 1.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Ets PF00178.22 PRP85274.1 - 0.017 15.6 0.5 3.3 8.2 0.1 2.4 1 1 1 2 2 2 0 Ets-domain BppL_N PF18338.1 PRP85274.1 - 0.083 12.7 6.5 1.2 9.0 0.5 2.3 2 0 0 2 2 2 0 Lower baseplate protein N-terminal domain PCNA_N PF00705.18 PRP85275.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Mito_carr PF00153.27 PRP85276.1 - 1.8e-39 133.5 3.7 5.7e-21 74.3 0.0 3.0 2 1 1 3 3 3 2 Mitochondrial carrier protein zf-3CxxC_2 PF17180.4 PRP85276.1 - 5.6e-11 43.0 8.5 1.3e-10 41.9 8.5 1.6 1 0 0 1 1 1 1 Zinc-binding domain Glyco_hydro_99 PF16317.5 PRP85277.1 - 9.1e-06 25.0 0.8 0.02 14.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 99 MIF4G PF02854.19 PRP85278.1 - 9e-64 215.0 39.7 4.2e-32 111.5 5.4 4.3 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 PRP85278.1 - 5.6e-29 101.6 9.2 5.6e-29 101.6 9.2 5.3 5 1 0 5 5 5 1 Up-frameshift suppressor 2 MMR_HSR1 PF01926.23 PRP85279.1 - 3.3e-23 82.0 0.9 7.4e-23 80.8 0.9 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP85279.1 - 5.7e-11 42.2 1.7 5.4e-10 39.0 0.3 2.2 1 1 1 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PRP85279.1 - 6.7e-08 32.8 7.5 0.0005 20.2 0.3 3.2 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 PRP85279.1 - 2.6e-07 30.2 1.1 5.1e-07 29.2 1.1 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 PRP85279.1 - 7.9e-07 29.1 0.0 0.00069 19.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase KH_2 PF07650.17 PRP85279.1 - 4.1e-06 26.5 0.4 4.1e-06 26.5 0.4 2.8 2 0 0 2 2 2 1 KH domain GTP_EFTU PF00009.27 PRP85279.1 - 1.7e-05 24.4 3.3 0.0054 16.3 0.5 3.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 PRP85279.1 - 0.0011 18.4 1.6 0.023 14.2 1.6 2.6 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PRP85279.1 - 0.0017 17.8 0.3 0.0017 17.8 0.3 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MeaB PF03308.16 PRP85279.1 - 0.0034 16.4 0.1 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 PRP85279.1 - 0.0044 16.6 2.2 0.18 11.4 0.3 2.5 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GBP PF02263.19 PRP85279.1 - 0.0064 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain PduV-EutP PF10662.9 PRP85279.1 - 0.011 15.5 0.3 3.4 7.4 0.2 3.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 PRP85279.1 - 0.018 15.1 0.0 0.06 13.4 0.0 2.0 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 PRP85279.1 - 0.03 14.8 0.2 0.03 14.8 0.2 2.2 2 1 0 2 2 2 0 ABC transporter Roc PF08477.13 PRP85279.1 - 0.039 14.2 0.5 0.56 10.4 0.5 2.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Galactosyl_T PF01762.21 PRP85280.1 - 2.4e-14 53.6 0.0 4.5e-09 36.4 0.0 2.4 1 1 1 2 2 2 2 Galactosyltransferase HA PF03457.14 PRP85280.1 - 0.11 12.8 0.2 0.32 11.3 0.2 1.8 1 0 0 1 1 1 0 Helicase associated domain PPR_2 PF13041.6 PRP85281.1 - 5.5e-45 151.3 20.6 1.8e-09 37.6 0.1 8.1 3 3 6 9 9 9 8 PPR repeat family PPR_3 PF13812.6 PRP85281.1 - 1.1e-32 111.8 10.5 1.8e-10 40.7 0.1 6.2 4 2 2 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 PRP85281.1 - 6.3e-27 91.9 0.6 0.00039 20.5 0.0 8.5 8 0 0 8 8 8 7 PPR repeat PPR_1 PF12854.7 PRP85281.1 - 3.7e-23 80.9 8.8 1.3e-05 24.8 0.0 7.7 9 0 0 9 9 9 5 PPR repeat PPR_long PF17177.4 PRP85281.1 - 1.6e-18 66.9 2.5 2.3e-05 23.8 0.0 4.0 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP HMD PF03201.16 PRP85281.1 - 0.018 15.3 2.3 3.6 7.9 0.1 3.5 2 1 1 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase CdiI_2 PF18593.1 PRP85281.1 - 0.018 15.7 0.1 15 6.3 0.0 3.8 4 0 0 4 4 4 0 CdiI immunity protein Sec23_trunk PF04811.15 PRP85281.1 - 0.03 13.9 0.2 0.3 10.6 0.2 2.4 1 1 0 1 1 1 0 Sec23/Sec24 trunk domain DUF4919 PF16266.5 PRP85281.1 - 0.22 11.5 3.6 3.3 7.6 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) SPC12 PF06645.13 PRP85282.1 - 6.3e-25 87.1 2.0 6.9e-25 86.9 2.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) FUN14 PF04930.15 PRP85282.1 - 0.005 17.2 0.2 0.0057 17.0 0.2 1.1 1 0 0 1 1 1 1 FUN14 family DUF4181 PF13789.6 PRP85282.1 - 0.01 16.1 0.3 0.011 16.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4181) DUF4564 PF15169.6 PRP85282.1 - 0.018 14.8 0.1 0.02 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) FAD_binding_1 PF00667.20 PRP85284.1 - 1.8e-31 109.4 0.0 3.1e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAGK_cat PF00781.24 PRP85284.1 - 1.1e-25 89.6 0.0 2.2e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_binding_1 PF00175.21 PRP85284.1 - 1.4e-11 45.0 0.0 4.4e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 PRP85284.1 - 0.024 14.8 0.0 0.081 13.0 0.0 1.9 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PH PF00169.29 PRP85284.1 - 0.068 13.7 0.2 2.5 8.7 0.0 2.5 2 0 0 2 2 2 0 PH domain CAF1C_H4-bd PF12265.8 PRP85285.1 - 4.6e-27 94.1 0.2 2.1e-25 88.8 0.2 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 PRP85285.1 - 2.1e-25 88.5 10.6 4.5e-07 30.5 0.3 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Ank_5 PF13857.6 PRP85285.1 - 1.7e-16 60.0 0.5 6.8e-12 45.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP85285.1 - 9.4e-16 58.2 0.0 3.3e-12 46.8 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 PRP85285.1 - 6.1e-14 51.7 0.0 4e-07 30.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP85285.1 - 1.2e-12 46.8 0.1 1.2e-05 25.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 PRP85285.1 - 1.3e-10 41.6 0.1 1.7e-09 38.0 0.0 3.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 PRP85286.1 - 2.1e-48 164.8 0.0 3.5e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85286.1 - 1.9e-44 152.0 0.0 3.3e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP85286.1 - 3.7e-11 43.0 0.0 1e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain PH PF00169.29 PRP85286.1 - 6e-11 42.8 0.1 1.2e-10 41.8 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP85286.1 - 0.0005 20.5 0.8 0.0019 18.6 0.8 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PRP85286.1 - 0.07 13.4 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_7 PF13499.6 PRP85287.1 - 1.7e-16 60.4 0.0 1.5e-08 35.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP85287.1 - 8.1e-13 47.2 0.0 1.6e-05 24.4 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 PRP85287.1 - 2.7e-12 45.3 0.0 9.2e-05 21.7 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 PRP85287.1 - 2.4e-08 33.7 0.1 7.8e-06 25.6 0.0 3.9 2 2 1 3 3 3 2 EF-hand domain pair TMEM135_C_rich PF15982.5 PRP85287.1 - 3.6e-05 24.4 2.5 0.00075 20.1 0.5 2.6 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 EF-hand_5 PF13202.6 PRP85287.1 - 4.9e-05 22.6 0.2 0.00024 20.5 0.0 2.3 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 PRP85287.1 - 0.012 15.5 0.1 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 PRP85287.1 - 0.014 15.4 0.1 6 7.0 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.9 PRP85287.1 - 0.034 14.5 0.0 0.1 13.0 0.0 1.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 PRP85287.1 - 0.085 13.2 0.0 0.42 11.0 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain DUF2666 PF10869.8 PRP85287.1 - 0.094 12.9 0.2 4.9 7.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) DUF5580 PF17743.1 PRP85287.1 - 0.1 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF4315 PF14193.6 PRP85287.1 - 0.12 12.4 0.3 0.58 10.2 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) Sec7 PF01369.20 PRP85288.1 - 4.6e-65 218.7 2.6 8.3e-65 217.9 2.6 1.4 1 0 0 1 1 1 1 Sec7 domain Ank_2 PF12796.7 PRP85288.1 - 8.6e-40 135.2 10.6 7.6e-11 42.5 0.0 5.5 3 2 3 6 6 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85288.1 - 3.6e-35 119.9 6.1 4e-10 40.0 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85288.1 - 8.4e-29 99.3 4.2 6.7e-06 26.3 0.3 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP85288.1 - 4.8e-27 93.2 5.9 0.0017 18.7 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 PRP85288.1 - 8.6e-27 90.2 5.0 0.002 18.4 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat PH PF00169.29 PRP85288.1 - 4.3e-22 78.6 0.1 1.2e-21 77.1 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PRP85288.1 - 1.2e-05 25.4 0.0 0.0056 16.9 0.1 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 PRP85288.1 - 3.3e-05 24.3 0.9 8.6e-05 22.9 0.2 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Coat_F PF07875.12 PRP85288.1 - 0.12 12.7 0.1 0.61 10.4 0.1 2.3 1 0 0 1 1 1 0 Coat F domain Mur_ligase PF01225.25 PRP85288.1 - 0.12 12.7 0.1 9.2 6.7 0.0 3.2 3 0 0 3 3 3 0 Mur ligase family, catalytic domain Tweety PF04906.13 PRP85290.1 - 0.00018 20.3 2.7 0.00018 20.3 2.7 3.1 1 1 1 2 2 2 1 Tweety Reticulon PF02453.17 PRP85290.1 - 0.25 11.3 0.0 0.25 11.3 0.0 3.6 3 0 0 3 3 3 0 Reticulon Cullin_Nedd8 PF10557.9 PRP85292.1 - 0.04 13.9 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 Cullin protein neddylation domain Zn_clus PF00172.18 PRP85292.1 - 0.088 12.9 5.6 0.15 12.2 5.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGEF PF00617.19 PRP85293.1 - 4.1e-56 190.0 0.1 7.9e-56 189.0 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain PH PF00169.29 PRP85293.1 - 8.8e-11 42.3 0.3 2.5e-10 40.8 0.3 1.8 1 0 0 1 1 1 1 PH domain RasGEF_N PF00618.20 PRP85293.1 - 1.5e-10 41.2 0.0 4e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif PH_9 PF15410.6 PRP85293.1 - 0.071 13.5 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 PRP85293.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 PRP85293.1 - 0.18 12.3 0.4 0.8 10.2 0.4 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain Aldo_ket_red PF00248.21 PRP85294.1 - 5.3e-41 140.7 0.0 5e-33 114.5 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Ank_2 PF12796.7 PRP85295.1 - 2.5e-12 47.2 0.8 0.00026 21.5 0.0 4.1 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85295.1 - 4.6e-08 33.4 0.1 0.00026 21.5 0.0 4.4 3 2 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85295.1 - 0.00026 21.2 0.9 58 4.8 0.0 6.6 7 1 1 8 8 8 1 Ankyrin repeat AA_permease_2 PF13520.6 PRP85296.1 - 2.4e-51 174.9 37.8 3e-51 174.6 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4713 PF15831.5 PRP85296.1 - 0.82 10.2 5.3 1.6 9.2 2.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4713) IBR PF01485.21 PRP85297.1 - 4.5e-21 74.8 48.7 2.2e-13 50.2 4.0 4.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 PRP85297.1 - 0.00032 20.5 5.6 0.00032 20.5 5.6 4.9 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP85297.1 - 0.0098 16.2 9.3 0.0098 16.2 9.3 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 PRP85297.1 - 0.014 15.3 7.3 0.014 15.3 7.3 4.6 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PRP85297.1 - 7.2 6.5 39.0 0.061 13.1 5.3 4.0 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain EGF_2 PF07974.13 PRP85298.1 - 1.4 9.3 8.8 3.3 8.1 8.8 1.6 1 0 0 1 1 1 0 EGF-like domain X8 PF07983.13 PRP85300.1 - 3.9e-19 69.1 15.9 4.7e-09 36.8 3.9 3.2 2 0 0 2 2 2 2 X8 domain Glyco_hydro_17 PF00332.18 PRP85300.1 - 1.8e-16 60.7 5.3 4.6e-12 46.2 0.5 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Carb_bind PF10645.9 PRP85300.1 - 0.013 15.7 15.2 0.013 15.7 15.2 3.0 2 1 1 3 3 3 0 Carbohydrate binding START PF01852.19 PRP85301.1 - 1.7e-07 30.9 0.9 0.004 16.6 0.1 3.3 3 0 0 3 3 3 2 START domain Zn_clus PF00172.18 PRP85301.1 - 2.9e-05 24.1 6.4 7.6e-05 22.8 6.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF1 PF04857.20 PRP85301.1 - 0.0046 16.2 0.2 0.53 9.4 0.0 2.6 3 0 0 3 3 3 2 CAF1 family ribonuclease TetR_C_2 PF08361.11 PRP85301.1 - 0.012 15.7 0.1 11 6.2 0.0 3.4 4 0 0 4 4 4 0 MAATS-type transcriptional repressor, C-terminal region Chlam_PMP PF02415.17 PRP85303.1 - 0.85 10.2 4.9 8.9 7.0 0.1 4.6 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat TPR_1 PF00515.28 PRP85305.1 - 2e-22 78.0 7.9 1e-05 25.1 0.0 7.5 6 2 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85305.1 - 3.6e-20 70.4 7.3 4.5e-06 26.4 0.1 6.9 6 2 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 PRP85305.1 - 1.5e-16 59.2 0.1 0.00024 21.1 0.0 6.4 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP85305.1 - 3.9e-15 56.2 4.6 0.00013 22.6 0.7 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_9 PF13371.6 PRP85305.1 - 7.8e-15 54.8 9.0 2.4e-06 27.6 0.2 3.7 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 PRP85305.1 - 2.5e-12 46.3 6.4 0.0013 19.0 0.4 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP85305.1 - 6.2e-11 41.8 9.0 0.0018 17.9 0.2 6.5 5 1 2 7 7 6 4 TPR repeat TPR_12 PF13424.6 PRP85305.1 - 1.6e-10 41.1 6.1 0.0031 17.7 0.2 4.0 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP85305.1 - 7.9e-10 39.1 6.2 0.0018 18.8 0.1 4.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP85305.1 - 4e-09 36.5 12.8 0.04 14.7 0.1 6.1 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP85305.1 - 9.1e-07 29.1 0.1 1.3 9.8 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP85305.1 - 3.6e-05 23.5 1.1 0.57 10.3 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 PRP85305.1 - 0.00013 22.4 2.8 0.046 14.2 0.1 3.7 2 2 0 2 2 2 1 Bacterial transcriptional activator domain DUF4192 PF13830.6 PRP85305.1 - 0.0028 17.8 0.1 0.0028 17.8 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4192) TPR_10 PF13374.6 PRP85305.1 - 0.0039 17.0 13.3 9 6.3 2.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat YfiO PF13525.6 PRP85305.1 - 0.004 16.9 0.0 0.029 14.1 0.0 2.0 1 1 1 2 2 2 1 Outer membrane lipoprotein TPR_15 PF13429.6 PRP85305.1 - 0.0047 16.2 0.5 0.16 11.1 0.3 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat MAS20 PF02064.15 PRP85305.1 - 0.0054 16.8 0.1 0.038 14.1 0.1 2.2 2 0 0 2 2 2 1 MAS20 protein import receptor TPR_20 PF14561.6 PRP85305.1 - 0.015 15.6 3.0 2.5 8.5 0.2 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat HSP20 PF00011.21 PRP85306.1 - 1.4e-19 70.1 1.3 1.9e-19 69.7 1.3 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP85306.1 - 8.4e-08 31.7 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DnaJ PF00226.31 PRP85306.1 - 0.1 12.8 0.3 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 DnaJ domain DUF2807 PF10988.8 PRP85306.1 - 0.11 12.3 1.2 0.64 9.8 0.2 1.9 1 1 1 2 2 2 0 Putative auto-transporter adhesin, head GIN domain BON PF04972.17 PRP85306.1 - 0.12 12.7 0.9 0.23 11.8 0.4 1.7 2 0 0 2 2 2 0 BON domain 60KD_IMP PF02096.20 PRP85307.1 - 2.6e-08 33.9 0.7 3.8e-08 33.4 0.7 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1324 PF07038.11 PRP85307.1 - 0.0087 16.3 0.3 0.022 15.0 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1324) ING PF12998.7 PRP85308.1 - 5.6e-27 94.3 4.6 8.5e-27 93.7 4.6 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 PRP85308.1 - 6.1e-06 26.0 7.4 1.3e-05 25.0 7.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 PRP85308.1 - 0.003 17.1 1.9 0.0052 16.3 1.9 1.4 1 0 0 1 1 1 1 PHD-finger SOGA PF11365.8 PRP85308.1 - 0.0034 18.5 0.6 0.0067 17.5 0.6 1.5 1 0 0 1 1 1 1 Protein SOGA zf-HC5HC2H PF13771.6 PRP85308.1 - 0.038 14.2 1.5 0.098 12.9 1.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain HMMR_N PF15905.5 PRP85308.1 - 0.044 13.3 10.9 0.058 12.9 10.9 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 PRP85308.1 - 0.17 11.4 2.0 0.2 11.2 2.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 PRP85308.1 - 0.55 10.3 2.4 0.83 9.7 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Methyltransf_11 PF08241.12 PRP85309.1 - 1.4e-07 32.0 0.0 2.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP85309.1 - 0.00041 21.0 0.0 0.0007 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP85309.1 - 0.0014 19.3 0.0 0.003 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP85309.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain HD_assoc PF13286.6 PRP85309.1 - 0.2 12.2 0.0 3.5 8.2 0.0 2.2 1 1 0 1 1 1 0 Phosphohydrolase-associated domain ADH_zinc_N PF00107.26 PRP85310.1 - 4.1e-25 88.2 1.4 6.8e-25 87.5 0.8 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP85310.1 - 1.7e-15 58.2 0.0 3.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP85310.1 - 3.4e-09 36.6 0.1 9.6e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 PRP85310.1 - 2.6e-06 27.1 1.8 4e-06 26.4 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ETF PF01012.21 PRP85310.1 - 0.0055 16.6 1.5 0.0096 15.8 1.5 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EIIA-man PF03610.16 PRP85310.1 - 0.0082 16.4 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 PTS system fructose IIA component ACP_syn_III_C PF08541.10 PRP85310.1 - 0.0088 16.2 0.1 0.019 15.1 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Epimerase PF01370.21 PRP85310.1 - 0.087 12.3 0.3 0.13 11.7 0.3 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Homeodomain PF00046.29 PRP85311.1 - 8.9e-15 54.3 1.7 1.2e-14 53.9 1.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP85311.1 - 0.00022 21.1 3.1 0.00022 21.1 3.1 1.8 1 1 1 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 PRP85312.1 - 7.5e-12 44.9 1.8 1.8e-11 43.7 1.8 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP85312.1 - 0.00037 20.3 0.6 0.0011 18.8 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain Amino_oxidase PF01593.24 PRP85314.1 - 1.8e-79 268.1 0.0 1.8e-78 264.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP85314.1 - 2.7e-11 43.5 0.6 4.8e-11 42.7 0.6 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PRP85314.1 - 2.2e-07 30.4 2.2 0.002 17.4 0.8 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP85314.1 - 2e-05 23.8 1.6 5.5e-05 22.4 0.8 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 PRP85314.1 - 0.00013 21.4 0.3 0.0011 18.3 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 PRP85314.1 - 0.0006 19.1 0.1 0.001 18.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 PRP85314.1 - 0.0027 17.3 4.3 0.02 14.5 4.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP85314.1 - 0.0035 16.6 0.5 0.0077 15.5 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP85314.1 - 0.0037 16.0 0.3 0.017 13.9 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 PRP85314.1 - 0.018 14.1 0.5 0.028 13.5 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 PRP85314.1 - 0.021 15.4 1.4 0.082 13.5 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP85314.1 - 0.027 14.5 1.0 7.4 6.5 0.5 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 PRP85314.1 - 0.056 12.8 2.4 0.092 12.1 1.7 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Haemagg_act PF05860.13 PRP85314.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 haemagglutination activity domain C2 PF00168.30 PRP85315.1 - 2.6e-22 79.1 0.1 5.8e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 C2 domain Glyco_hydro_77 PF02446.17 PRP85316.1 - 1.7e-124 416.2 0.1 1.2e-123 413.4 0.1 2.0 2 0 0 2 2 2 1 4-alpha-glucanotransferase Sugar_tr PF00083.24 PRP85316.1 - 2.3e-120 402.5 20.4 3.3e-120 402.0 20.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP85316.1 - 8.8e-26 90.6 23.2 7.7e-21 74.4 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_48 PF02922.18 PRP85316.1 - 3.5e-17 62.5 0.0 1.1e-16 61.0 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 PRP85316.1 - 2.3e-13 50.4 5.0 1.5e-08 34.6 0.4 3.4 2 1 1 3 3 3 2 Alpha amylase, catalytic domain LppA PF16708.5 PRP85316.1 - 0.077 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Lipoprotein confined to pathogenic Mycobacterium YqhR PF11085.8 PRP85316.1 - 0.19 11.6 6.4 0.044 13.7 0.3 2.6 3 0 0 3 3 3 0 Conserved membrane protein YqhR MFS_1_like PF12832.7 PRP85316.1 - 2.8 6.7 12.7 0.077 11.8 3.3 2.5 2 1 1 3 3 3 0 MFS_1 like family YLP PF02757.17 PRP85317.1 - 0.39 10.8 4.4 5 7.4 0.1 2.7 2 0 0 2 2 2 0 YLP motif DPBB_1 PF03330.18 PRP85318.1 - 4.1e-10 39.8 0.1 1e-09 38.5 0.1 1.8 1 1 0 1 1 1 1 Lytic transglycolase RhoGAP PF00620.27 PRP85319.1 - 5.8e-39 133.4 0.0 8.9e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 PRP85319.1 - 1.1e-30 106.5 0.6 2.6e-30 105.4 0.1 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 PRP85319.1 - 1.2e-17 64.0 0.4 1.1e-16 61.0 0.1 2.5 3 1 0 3 3 3 1 CRAL/TRIO domain ARL2_Bind_BART PF11527.8 PRP85320.1 - 1.7e-21 76.5 1.1 2.3e-21 76.1 1.1 1.1 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART eIF-3c_N PF05470.12 PRP85321.1 - 4.8e-178 593.2 28.3 2.3e-174 581.0 28.3 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 PRP85321.1 - 3.1e-14 53.4 0.1 3.4e-13 50.0 0.0 2.7 2 0 0 2 2 2 1 PCI domain Retrotrans_gag PF03732.17 PRP85321.1 - 0.061 13.6 0.4 1.3 9.3 0.1 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein CBP4 PF07960.11 PRP85321.1 - 4.4 7.1 9.2 1.1 9.1 0.7 2.9 2 0 0 2 2 2 0 CBP4 F-box PF00646.33 PRP85322.1 - 2.8e-06 27.1 0.2 1.1e-05 25.1 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 PRP85322.1 - 0.0013 18.6 0.1 0.003 17.4 0.1 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 PRP85322.1 - 0.051 13.5 1.5 0.094 12.6 0.5 2.0 2 0 0 2 2 2 0 F-box-like Tweety PF04906.13 PRP85323.1 - 1.2e-05 24.2 4.3 0.0032 16.2 1.7 2.5 1 1 1 2 2 2 2 Tweety Prominin PF05478.11 PRP85323.1 - 0.00099 17.2 4.7 0.15 10.0 0.0 2.6 2 1 1 3 3 3 2 Prominin BCDHK_Adom3 PF10436.9 PRP85323.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3561 PF12084.8 PRP85323.1 - 1.4 9.0 7.0 1.7 8.7 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) DUF1772 PF08592.11 PRP85324.1 - 2.7e-10 40.7 0.0 3.4e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) EGF_2 PF07974.13 PRP85325.1 - 0.0005 20.4 6.7 0.0005 20.4 6.7 2.2 3 0 0 3 3 3 1 EGF-like domain ARL6IP6 PF15062.6 PRP85326.1 - 0.044 13.9 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix WD40 PF00400.32 PRP85327.1 - 1.4e-21 76.4 10.1 4.7e-06 27.2 0.2 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP85327.1 - 1.4e-07 31.8 0.1 0.38 11.1 0.0 4.0 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PAS_8 PF13188.7 PRP85327.1 - 0.02 14.9 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 PAS domain Golgin_A5 PF09787.9 PRP85328.1 - 0.0025 17.3 10.4 0.005 16.3 10.4 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 zf-Nse PF11789.8 PRP85329.1 - 8.1e-20 70.4 1.2 1.4e-19 69.7 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 PRP85329.1 - 8e-06 25.5 0.9 1.4e-05 24.8 0.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 PRP85329.1 - 3.3e-05 23.8 0.3 5.9e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 PRP85329.1 - 0.022 14.9 0.3 0.054 13.7 0.1 1.8 2 0 0 2 2 2 0 U-box domain zf-C3HC4_4 PF15227.6 PRP85329.1 - 0.029 14.5 0.2 0.054 13.7 0.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PRP85329.1 - 0.029 14.2 0.4 0.055 13.3 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP85329.1 - 0.031 14.6 0.2 0.066 13.5 0.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PRP85329.1 - 0.04 14.3 0.7 0.07 13.5 0.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Mss51 PF13824.6 PRP85329.1 - 0.13 12.3 1.2 0.49 10.5 1.2 2.0 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2963 PF11178.8 PRP85329.1 - 0.89 9.3 7.9 2 8.2 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2963) Phage_HK97_TLTM PF06120.11 PRP85329.1 - 1.7 7.7 8.6 0.76 8.9 6.2 1.6 1 1 0 1 1 1 0 Tail length tape measure protein Beta_helix PF13229.6 PRP85330.1 - 7.2e-08 32.4 28.2 0.0013 18.6 3.7 4.1 3 1 1 4 4 4 3 Right handed beta helix region DUF5123 PF17161.4 PRP85330.1 - 2.9 9.0 6.9 1.7 9.7 3.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5123) Ank_2 PF12796.7 PRP85331.1 - 4.8e-11 43.1 0.0 0.0016 19.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP85331.1 - 6.6e-05 23.0 1.0 52 4.9 0.0 5.8 6 0 0 6 6 6 0 Ankyrin repeat Ank_5 PF13857.6 PRP85331.1 - 0.00021 21.5 0.9 11 6.5 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) F-box PF00646.33 PRP85331.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain Ank PF00023.30 PRP85331.1 - 0.1 13.1 1.1 8.5 7.0 0.1 4.0 5 0 0 5 5 5 0 Ankyrin repeat EpuA PF11772.8 PRP85331.1 - 0.23 11.2 0.0 0.48 10.1 0.0 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Cullin PF00888.22 PRP85332.1 - 1.6e-17 63.4 0.1 3.9e-16 58.8 0.0 2.7 2 1 0 2 2 2 1 Cullin family DSPc PF00782.20 PRP85332.1 - 0.0037 17.1 0.2 0.096 12.5 0.0 2.5 1 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain MIP PF00230.20 PRP85333.1 - 1.8e-29 103.1 9.0 2.3e-29 102.8 9.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Spc29 PF17082.5 PRP85335.1 - 0.067 13.0 5.0 0.064 13.1 3.5 1.5 1 1 0 1 1 1 0 Spindle Pole Component 29 Exonuc_VII_L PF02601.15 PRP85335.1 - 0.072 12.7 6.6 0.088 12.4 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 PRP85335.1 - 0.85 9.2 9.2 2.5 7.6 9.2 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ERM PF00769.19 PRP85335.1 - 1.7 8.4 19.8 2.6 7.8 19.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 PRP85335.1 - 5.4 7.7 16.7 0.9 10.2 10.5 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2203 PF09969.9 PRP85335.1 - 5.5 7.7 11.8 6.3 7.6 0.7 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) FUSC PF04632.12 PRP85335.1 - 7.6 4.9 5.0 9.7 4.6 5.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HicA_toxin PF07927.12 PRP85337.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, Homeodomain PF00046.29 PRP85338.1 - 5.2e-16 58.2 6.4 7.2e-16 57.8 6.4 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP85338.1 - 1.4e-07 31.3 0.3 1.4e-07 31.3 0.3 1.6 2 0 0 2 2 2 1 Homeobox KN domain PPTA PF01239.22 PRP85339.1 - 5.9e-38 127.5 13.2 8.9e-10 38.0 0.7 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Cylicin_N PF15241.6 PRP85339.1 - 0.12 12.5 1.6 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Cylicin N-terminus Ank_2 PF12796.7 PRP85342.1 - 1.9e-82 271.9 0.2 1.4e-09 38.4 0.0 7.7 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85342.1 - 3e-47 158.4 8.8 3.1e-06 27.6 0.5 11.8 5 3 8 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85342.1 - 1.2e-37 127.4 7.0 0.0068 16.7 0.0 15.4 8 4 9 17 17 17 9 Ankyrin repeats (many copies) Ank PF00023.30 PRP85342.1 - 2.5e-27 94.1 19.1 0.37 11.3 0.0 15.5 15 1 1 16 16 16 8 Ankyrin repeat Ank_3 PF13606.6 PRP85342.1 - 2.8e-20 70.3 4.1 3.5 8.5 0.0 14.6 16 1 1 17 17 17 2 Ankyrin repeat HyaE PF07449.11 PRP85342.1 - 0.023 14.7 3.3 18 5.4 0.0 5.7 3 1 5 8 8 8 0 Hydrogenase-1 expression protein HyaE DUF4671 PF15710.5 PRP85342.1 - 0.031 13.1 1.5 1.5 7.6 0.0 3.5 2 2 3 5 5 5 0 Domain of unknown function (DUF4671) Hairy_orange PF07527.13 PRP85342.1 - 0.083 13.1 0.1 1.7e+02 2.5 0.0 5.6 6 0 0 6 6 6 0 Hairy Orange Thioredoxin PF00085.20 PRP85343.1 - 7.7e-26 90.1 0.4 3.1e-19 68.9 0.1 2.9 2 0 0 2 2 2 2 Thioredoxin bZIP_1 PF00170.21 PRP85343.1 - 9.1e-12 44.9 9.1 2.4e-11 43.6 7.1 2.5 2 0 0 2 2 2 1 bZIP transcription factor Thioredoxin_6 PF13848.6 PRP85343.1 - 1.1e-10 41.8 0.1 0.00025 21.0 0.0 3.6 2 1 0 2 2 2 2 Thioredoxin-like domain bZIP_2 PF07716.15 PRP85343.1 - 1.3e-09 38.0 3.8 1.3e-09 38.0 3.8 2.4 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 PRP85343.1 - 8.7e-06 26.2 9.4 1.7e-05 25.2 9.4 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Thioredoxin_2 PF13098.6 PRP85343.1 - 1.2e-05 25.7 0.2 0.27 11.7 0.1 3.5 3 0 0 3 3 3 2 Thioredoxin-like domain SOGA PF11365.8 PRP85343.1 - 0.00055 21.0 0.0 0.0017 19.4 0.0 1.9 1 0 0 1 1 1 1 Protein SOGA TMF_TATA_bd PF12325.8 PRP85343.1 - 0.0032 17.7 1.7 0.0094 16.2 1.7 1.8 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Thioredoxin_8 PF13905.6 PRP85343.1 - 0.037 14.4 0.2 18 5.7 0.1 2.9 2 0 0 2 2 2 0 Thioredoxin-like TSC22 PF01166.18 PRP85343.1 - 0.13 12.6 0.1 0.38 11.1 0.1 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family V_ATPase_I PF01496.19 PRP85343.1 - 0.14 10.0 2.7 0.21 9.5 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 PRP85343.1 - 0.49 10.5 6.6 1.1 9.3 6.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AT_hook PF02178.19 PRP85343.1 - 2.5 8.2 6.5 7.1 6.9 6.5 1.8 1 0 0 1 1 1 0 AT hook motif HA2 PF04408.23 PRP85344.1 - 5.7e-19 68.4 0.1 1.7e-18 66.9 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PRP85344.1 - 1.9e-17 63.3 0.1 3.7e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PRP85344.1 - 9.2e-17 61.4 0.0 5.6e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PRP85344.1 - 1.5e-06 28.5 0.0 3.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 PRP85344.1 - 8.4e-06 25.7 1.3 0.0001 22.1 0.9 2.9 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 PRP85344.1 - 3.1e-05 23.8 0.1 5.1e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP85344.1 - 0.0064 16.8 0.1 0.012 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 PRP85344.1 - 0.026 14.0 0.0 0.089 12.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 PRP85344.1 - 0.054 14.0 0.4 0.85 10.1 0.1 2.4 1 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 PRP85344.1 - 0.065 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 PRP85344.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 PRP85344.1 - 0.074 13.5 3.8 0.099 13.1 1.1 2.4 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 PRP85344.1 - 0.13 11.2 0.2 0.27 10.1 0.1 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zip PF02535.22 PRP85346.1 - 1.8 7.7 4.9 2.3 7.4 4.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PI3K_1B_p101 PF10486.9 PRP85346.1 - 7.2 4.3 14.5 9.3 3.9 14.5 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF4746 PF15928.5 PRP85346.1 - 9.2 5.6 12.1 13 5.1 12.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) GTP_EFTU PF00009.27 PRP85349.1 - 0.00042 19.9 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FIIND PF13553.6 PRP85350.1 - 0.033 13.6 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Function to find Ank_2 PF12796.7 PRP85351.1 - 3.3e-28 98.1 0.3 6.1e-09 36.4 0.0 5.4 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85351.1 - 3.5e-22 78.5 3.2 2.3e-06 28.1 0.0 7.7 4 3 5 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85351.1 - 1.9e-19 69.5 10.7 0.069 13.5 0.1 9.6 6 2 5 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85351.1 - 4e-14 51.3 1.8 0.69 10.7 0.0 9.9 12 0 0 12 12 12 2 Ankyrin repeat Ank PF00023.30 PRP85351.1 - 3e-11 43.3 14.8 0.77 10.3 0.0 9.5 11 1 0 11 11 11 3 Ankyrin repeat DUF447 PF04289.12 PRP85351.1 - 0.019 14.8 0.4 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF447) PRODH PF18327.1 PRP85351.1 - 0.057 13.6 13.1 34 4.8 0.1 6.5 9 0 0 9 9 9 0 Proline utilization A proline dehydrogenase N-terminal domain DDR PF08841.10 PRP85351.1 - 0.077 12.0 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain ADSL_C PF10397.9 PRP85351.1 - 0.13 12.8 3.9 78 3.9 0.3 5.2 2 2 1 3 3 3 0 Adenylosuccinate lyase C-terminus GAS2 PF02187.17 PRP85352.1 - 3.5e-10 39.8 1.5 2e-09 37.4 0.1 3.0 2 0 0 2 2 2 1 Growth-Arrest-Specific Protein 2 Domain AMPK1_CBM PF16561.5 PRP85352.1 - 3.9e-10 39.8 0.1 9.2e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase EF-hand_1 PF00036.32 PRP85352.1 - 2.8e-06 26.5 0.6 0.048 13.2 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP85352.1 - 0.00088 19.0 1.2 1.5 9.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_19 PF13245.6 PRP85352.1 - 0.0021 18.4 0.1 0.03 14.7 0.1 2.9 1 1 0 1 1 1 1 AAA domain EF-hand_8 PF13833.6 PRP85352.1 - 0.064 13.1 0.2 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair GGACT PF06094.12 PRP85353.1 - 3.8e-18 66.3 0.1 7.8e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like D123 PF07065.14 PRP85353.1 - 7.4e-10 38.5 1.5 1.8e-09 37.2 0.1 2.2 3 0 0 3 3 3 1 D123 AIG2_2 PF13772.6 PRP85353.1 - 2.3e-06 27.9 0.2 5.6e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 AIG2-like family R2K_3 PF14243.6 PRP85353.1 - 0.0026 17.8 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 PRP85353.1 - 0.041 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 DUF4334 PF14232.6 PRP85353.1 - 0.085 12.8 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4334) LRR_8 PF13855.6 PRP85354.1 - 1.1e-62 207.7 122.5 2.3e-09 36.9 1.8 16.1 13 3 2 16 16 16 14 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP85354.1 - 2e-47 161.7 0.0 1.9e-35 122.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PRP85354.1 - 1.2e-42 143.2 127.0 1.8e-07 31.3 0.7 20.8 12 5 12 26 26 26 17 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP85354.1 - 1.2e-28 100.2 0.0 2.7e-18 66.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain LRR_6 PF13516.6 PRP85354.1 - 5.1e-10 38.6 97.7 0.54 10.5 0.1 25.7 29 0 0 29 29 28 6 Leucine Rich repeat LRR_1 PF00560.33 PRP85354.1 - 9.2e-09 34.7 117.0 2.8 8.8 0.1 28.8 31 2 1 32 32 32 3 Leucine Rich Repeat DUF2627 PF11118.8 PRP85354.1 - 0.073 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) LRR_9 PF14580.6 PRP85354.1 - 0.093 12.2 25.7 1.6 8.2 1.8 6.2 5 2 1 6 6 6 0 Leucine-rich repeat NOB1_Zn_bind PF08772.11 PRP85354.1 - 0.12 12.5 0.6 1.3 9.2 0.2 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like TMEM132D_C PF15706.5 PRP85354.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SKG6 PF08693.10 PRP85354.1 - 0.12 11.8 3.9 0.26 10.7 3.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_5 PF13306.6 PRP85354.1 - 0.17 11.8 22.8 0.084 12.8 2.0 5.5 4 1 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) E3_UFM1_ligase PF09743.9 PRP85355.1 - 2.3e-90 302.9 4.8 4.4e-90 302.0 4.8 1.5 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 PRP85355.1 - 0.024 14.7 1.3 2.6 8.2 0.1 3.3 3 0 0 3 3 3 0 FeoC like transcriptional regulator DUF2052 PF09747.9 PRP85355.1 - 1.5 8.9 5.6 5.7 7.0 5.6 1.9 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) His_Phos_2 PF00328.22 PRP85356.1 - 4e-30 105.4 0.0 5.3e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase_Tyr PF07714.17 PRP85357.1 - 5.7e-43 147.1 0.0 1.1e-42 146.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 PRP85357.1 - 8.8e-35 117.1 0.2 3.8e-08 32.8 0.4 7.0 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85357.1 - 2.2e-32 108.5 5.9 2.3e-06 27.3 0.3 8.6 9 0 0 9 9 9 5 Tetratricopeptide repeat Pkinase PF00069.25 PRP85357.1 - 5.3e-28 98.1 0.0 1e-27 97.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPR_8 PF13181.6 PRP85357.1 - 1.4e-25 87.3 4.1 0.0011 19.0 0.5 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 PRP85357.1 - 2.3e-25 89.0 0.0 1.9e-06 28.4 0.0 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 PRP85357.1 - 1.6e-19 69.2 0.1 4.6e-06 26.2 0.0 6.3 4 1 4 8 8 7 3 TPR repeat TPR_12 PF13424.6 PRP85357.1 - 2e-19 69.6 6.0 2.8e-09 37.2 0.0 7.0 5 3 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP85357.1 - 3.1e-18 65.8 9.6 1.6e-06 28.2 1.8 4.8 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP85357.1 - 2.2e-16 60.1 1.2 0.00011 22.6 0.1 6.1 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 PRP85357.1 - 1.1e-13 50.5 0.9 0.93 10.0 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 PRP85357.1 - 1.2e-13 50.0 0.6 0.0073 16.3 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP85357.1 - 6.3e-13 48.4 0.7 0.75 10.8 0.0 7.3 2 1 4 6 6 6 3 Tetratricopeptide repeat GPS PF01825.21 PRP85357.1 - 3.2e-08 34.0 8.7 1.1e-07 32.3 8.7 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif TPR_9 PF13371.6 PRP85357.1 - 6e-08 32.7 1.9 0.37 11.0 0.0 5.1 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 PRP85357.1 - 2e-07 30.7 7.2 0.011 15.5 0.0 5.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP85357.1 - 8.5e-05 22.9 6.8 11 6.9 0.0 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 PRP85357.1 - 0.0011 18.7 0.3 0.55 9.9 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat-like domain DUF3856 PF12968.7 PRP85357.1 - 0.11 12.6 0.3 21 5.2 0.1 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 PRP85357.1 - 0.11 13.2 0.1 39 5.3 0.0 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat GPCR_chapero_1 PF11904.8 PRP85358.1 - 2.7e-47 161.7 0.9 1.8e-27 96.6 0.9 2.3 1 1 1 2 2 2 2 GPCR-chaperone Ank_4 PF13637.6 PRP85358.1 - 1.2e-08 35.3 0.6 2.9e-05 24.5 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP85358.1 - 1.6e-07 31.8 0.1 2.5e-06 28.0 0.1 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP85358.1 - 2.8e-07 30.7 0.1 1.5e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85358.1 - 2.4e-05 24.4 0.2 0.0033 17.8 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 PRP85358.1 - 7.1e-05 23.1 0.1 0.0015 18.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Nucleo_P87 PF07267.11 PRP85359.1 - 4.3 6.1 25.9 5.3 5.8 25.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_C11 PF03415.14 PRP85360.1 - 0.05 13.0 0.1 0.09 12.2 0.1 1.3 1 0 0 1 1 1 0 Clostripain family UPF0139 PF03669.13 PRP85361.1 - 0.18 11.7 2.0 0.26 11.2 1.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) Exo_endo_phos PF03372.23 PRP85362.1 - 0.0024 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3719 PF12516.8 PRP85364.1 - 0.00028 20.5 1.4 0.001 18.7 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3719) Pneumo_att_G PF05539.11 PRP85364.1 - 6.6 6.2 13.6 11 5.5 13.6 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G TMPIT PF07851.13 PRP85366.1 - 3.5e-81 273.0 5.3 4.3e-81 272.7 5.3 1.1 1 0 0 1 1 1 1 TMPIT-like protein MutS_III PF05192.18 PRP85366.1 - 0.017 15.3 0.1 0.022 15.0 0.1 1.3 1 0 0 1 1 1 0 MutS domain III Fib_alpha PF08702.10 PRP85366.1 - 0.025 14.8 2.2 0.045 13.9 2.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MetOD2 PF18548.1 PRP85366.1 - 0.46 10.6 2.4 1.1 9.4 1.8 1.9 1 1 0 1 1 1 0 Metanogen output domain 2 His_biosynth PF00977.21 PRP85367.1 - 2.1e-81 272.8 1.2 3e-81 272.2 1.2 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 PRP85367.1 - 5.9e-13 48.6 0.4 3.4e-08 32.9 0.2 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.14 PRP85367.1 - 2.1e-12 46.9 0.5 3e-07 30.0 0.1 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 PRP85367.1 - 1.9e-11 43.7 0.3 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase NMO PF03060.15 PRP85367.1 - 2.5e-11 43.6 2.6 3e-06 26.8 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 PRP85367.1 - 4.5e-10 39.0 1.6 0.00028 20.0 0.2 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 PRP85367.1 - 2.6e-09 36.6 0.4 0.0012 17.9 0.0 2.5 2 0 0 2 2 2 2 FMN-dependent dehydrogenase GATase PF00117.28 PRP85367.1 - 3.3e-09 36.8 0.0 6.9e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I TMP-TENI PF02581.17 PRP85367.1 - 5.1e-09 35.7 1.3 9.1e-05 21.9 0.4 2.5 2 0 0 2 2 2 2 Thiamine monophosphate synthase G3P_antiterm PF04309.12 PRP85367.1 - 8.9e-08 31.7 1.1 0.0049 16.3 0.2 2.5 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator PcrB PF01884.17 PRP85367.1 - 1.7e-05 24.4 1.5 0.0038 16.7 0.2 2.3 2 0 0 2 2 2 2 PcrB family Trp_syntA PF00290.20 PRP85367.1 - 8.5e-05 21.5 1.0 0.0049 15.7 0.2 2.2 2 0 0 2 2 2 1 Tryptophan synthase alpha chain GATase_3 PF07685.14 PRP85367.1 - 8.8e-05 22.2 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain NanE PF04131.14 PRP85367.1 - 0.0015 17.7 1.0 0.79 8.9 0.5 2.5 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase PEP_mutase PF13714.6 PRP85367.1 - 0.0044 16.5 1.4 0.89 9.0 0.0 2.8 2 1 1 3 3 3 1 Phosphoenolpyruvate phosphomutase BtpA PF03437.15 PRP85367.1 - 0.04 13.3 1.3 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 BtpA family IGPS PF00218.21 PRP85367.1 - 0.064 12.4 0.1 6 5.9 0.1 2.5 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase SNO PF01174.19 PRP85367.1 - 0.068 13.0 0.0 0.24 11.2 0.0 1.9 1 1 0 1 1 1 0 SNO glutamine amidotransferase family mit_SMPDase PF14724.6 PRP85368.1 - 1.6e-11 43.0 0.6 8.7e-08 30.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial-associated sphingomyelin phosphodiesterase DUF4131 PF13567.6 PRP85370.1 - 0.019 14.6 0.7 0.06 13.0 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Rrp15p PF07890.12 PRP85371.1 - 1.9e-15 57.4 11.4 1.9e-15 57.4 11.4 2.4 2 0 0 2 2 2 1 Rrp15p YL1 PF05764.13 PRP85371.1 - 0.05 13.7 28.3 0.085 13.0 28.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein MctB PF11382.8 PRP85371.1 - 1 9.0 3.9 0.39 10.4 1.3 1.5 2 0 0 2 2 2 0 Copper transport outer membrane protein, MctB DUF726 PF05277.12 PRP85372.1 - 3.6e-98 328.7 0.3 4.7e-98 328.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Phage_holin_3_6 PF07332.11 PRP85372.1 - 0.074 13.1 3.0 0.16 12.0 3.0 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1722 PF08349.11 PRP85373.1 - 0.0024 18.1 0.4 0.0024 18.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) RdRP PF05183.12 PRP85374.1 - 2.8e-117 392.8 0.0 4.1e-117 392.3 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase Helicase_C PF00271.31 PRP85374.1 - 4.8e-13 49.4 2.6 4.9e-13 49.4 0.4 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP85374.1 - 7.2e-11 42.2 0.0 4.1e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP85374.1 - 7.7e-10 39.0 0.0 9e-09 35.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit GatB_Yqey PF02637.18 PRP85374.1 - 0.016 15.1 0.1 0.065 13.1 0.1 2.0 1 0 0 1 1 1 0 GatB domain TniB PF05621.11 PRP85374.1 - 0.09 12.2 0.1 1.2 8.5 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein Peptidase_C1 PF00112.23 PRP85375.1 - 4.6e-44 151.1 9.6 1e-43 150.0 9.6 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP85375.1 - 2.5e-07 31.0 3.3 6.2e-07 29.8 3.3 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP85375.1 - 6e-06 25.3 0.7 0.00054 18.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PAN_1 PF00024.26 PRP85375.1 - 1.4e-05 25.0 2.8 4.4e-05 23.4 1.8 2.3 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.6 PRP85375.1 - 0.00027 20.8 4.5 0.0018 18.1 4.5 2.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP85375.1 - 0.0032 17.6 1.3 0.0032 17.6 1.3 2.5 2 1 0 2 2 2 1 PAN-like domain Peptidase_M49 PF03571.15 PRP85376.1 - 6.4e-229 760.9 0.4 7.5e-229 760.7 0.4 1.0 1 0 0 1 1 1 1 Peptidase family M49 Gpr1_Fun34_YaaH PF01184.19 PRP85377.1 - 2.9e-42 144.7 18.9 4.7e-42 144.0 18.9 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family LRR_6 PF13516.6 PRP85377.1 - 1.7e-12 46.3 30.4 0.0051 16.8 0.1 11.0 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 PRP85377.1 - 1.3e-09 38.2 25.5 0.0096 16.3 0.2 9.0 8 2 3 12 12 12 5 Leucine Rich repeats (2 copies) DUF87 PF01935.17 PRP85377.1 - 0.015 15.4 1.7 0.77 9.8 0.1 3.2 2 0 0 2 2 2 0 Helicase HerA, central domain KAP_NTPase PF07693.14 PRP85377.1 - 0.04 13.2 0.0 0.2 10.8 0.0 2.2 2 1 0 2 2 2 0 KAP family P-loop domain LRR_2 PF07723.13 PRP85377.1 - 0.47 11.2 4.7 79 4.2 0.1 4.6 3 0 0 3 3 3 0 Leucine Rich Repeat DUF872 PF05915.12 PRP85377.1 - 4.7 7.4 6.8 14 5.9 6.8 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) LuxE PF04443.12 PRP85378.1 - 0.015 14.4 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE 4HBT PF03061.22 PRP85379.1 - 0.0096 16.3 0.0 0.32 11.4 0.0 2.9 3 0 0 3 3 3 1 Thioesterase superfamily Redoxin PF08534.10 PRP85381.1 - 4.4e-29 101.1 0.1 5.3e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PRP85381.1 - 1.2e-10 41.4 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family PAPS_reduct PF01507.19 PRP85382.1 - 1.7e-26 93.3 0.0 2.6e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DSPc PF00782.20 PRP85383.1 - 8.6e-27 93.6 1.2 3.6e-24 85.1 0.2 2.6 1 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP85383.1 - 0.0063 16.1 1.4 0.0063 16.1 1.4 2.2 2 1 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 PRP85384.1 - 3.4e-34 117.5 0.0 5.8e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 PRP85384.1 - 4.5e-19 68.0 14.2 9.7e-10 38.1 0.6 6.2 5 2 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PRP85384.1 - 7e-17 61.3 22.6 0.00014 22.2 0.1 7.5 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP85384.1 - 1e-06 28.4 7.6 0.0076 15.8 0.4 3.4 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 PRP85384.1 - 2e-05 24.5 26.3 0.063 13.8 0.1 8.6 10 0 0 10 10 10 2 Leucine Rich Repeat Y_phosphatase PF00102.27 PRP85384.1 - 0.0022 17.6 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_6 PF13516.6 PRP85384.1 - 6.1 7.2 21.5 2.9 8.2 0.6 6.4 7 0 0 7 7 7 0 Leucine Rich repeat GATase_5 PF13507.6 PRP85385.1 - 5.3e-96 320.7 0.0 7.8e-96 320.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 PRP85385.1 - 1e-34 119.9 1.6 5.2e-20 72.1 0.5 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 PRP85385.1 - 1.6e-22 79.7 0.0 3.2e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 PRP85385.1 - 4.6e-13 49.5 0.1 1.2e-12 48.2 0.1 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain PAP2 PF01569.21 PRP85386.1 - 2e-17 63.2 7.6 2e-17 63.2 7.6 3.2 2 2 2 4 4 4 1 PAP2 superfamily PAP2_3 PF14378.6 PRP85386.1 - 0.00053 19.7 8.5 0.00053 19.7 8.5 2.0 1 1 0 1 1 1 1 PAP2 superfamily DUF2070 PF09843.9 PRP85386.1 - 9.5 4.4 11.9 13 3.9 11.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PEP-utilisers_N PF05524.13 PRP85388.1 - 0.1 12.8 0.4 0.19 11.9 0.4 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal VID27 PF08553.10 PRP85389.1 - 1.7e-10 40.5 0.0 2.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Chromo PF00385.24 PRP85390.1 - 2e-06 27.6 0.1 3.7e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Voltage_CLC PF00654.20 PRP85391.1 - 6.5e-51 173.6 13.2 6.5e-51 173.6 13.2 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel Pkinase_Tyr PF07714.17 PRP85392.1 - 4.7e-42 144.1 0.8 9.1e-42 143.1 0.8 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85392.1 - 3.7e-25 88.8 0.6 8.1e-25 87.7 0.6 1.5 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP85392.1 - 2.6e-07 31.1 3.8 7.1e-07 29.7 3.8 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Adeno_E1B_55K PF01696.17 PRP85392.1 - 0.00027 19.7 0.7 0.00027 19.7 0.7 2.4 2 1 1 3 3 3 1 Adenovirus EB1 55K protein / large t-antigen Kinase-like PF14531.6 PRP85392.1 - 0.00084 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Orf78 PF06024.12 PRP85392.1 - 0.076 13.3 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Pkinase_Tyr PF07714.17 PRP85393.1 - 7.2e-49 166.4 0.0 1.2e-48 165.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85393.1 - 1.9e-36 125.8 0.2 3.4e-36 125.0 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP85393.1 - 1.6e-06 28.6 5.1 5.2e-06 26.9 5.1 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP85393.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Insulin_TMD PF17870.1 PRP85393.1 - 0.043 13.9 0.5 0.1 12.7 0.5 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Kdo PF06293.14 PRP85393.1 - 0.08 12.3 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 PRP85394.1 - 1e-22 80.7 0.2 1.3e-13 50.9 0.0 3.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP85394.1 - 1.5e-15 57.2 5.9 5.3e-08 32.6 0.1 3.4 2 2 1 3 3 3 2 Protein kinase domain GPS PF01825.21 PRP85394.1 - 1.6e-08 34.9 3.9 9.5e-08 32.5 3.9 2.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Plasmodium_HRP PF05403.11 PRP85394.1 - 0.042 13.6 0.0 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) RINGv PF12906.7 PRP85395.1 - 3.6e-14 52.6 6.3 6e-14 51.9 6.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 PRP85395.1 - 0.56 10.6 7.5 1 9.8 7.5 1.4 1 0 0 1 1 1 0 Ring finger domain Synaphin PF05835.12 PRP85396.1 - 0.00013 22.3 0.3 0.00016 22.0 0.3 1.2 1 0 0 1 1 1 1 Synaphin protein Trypan_PARP PF05887.11 PRP85396.1 - 0.014 15.4 1.1 0.017 15.1 1.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 PRP85396.1 - 0.07 12.3 0.5 0.081 12.1 0.5 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 EHN PF06441.12 PRP85397.1 - 5e-37 126.6 0.2 9.2e-37 125.7 0.2 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 PRP85397.1 - 6.4e-14 52.2 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP85397.1 - 8.9e-06 26.5 0.0 1.6e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNase_HII PF01351.18 PRP85398.1 - 1.5e-39 135.9 0.0 1.8e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII YebF PF13995.6 PRP85398.1 - 0.12 12.3 0.2 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 YebF-like protein Pkinase PF00069.25 PRP85399.1 - 2.9e-19 69.5 0.3 1.4e-18 67.2 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP85399.1 - 9.1e-18 64.1 48.0 4.8e-05 23.6 1.7 8.2 6 1 3 9 9 9 4 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP85399.1 - 1.9e-16 60.2 0.1 1.4e-15 57.3 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP85399.1 - 1.7e-11 43.7 34.2 8.3e-06 25.5 6.3 6.5 4 2 5 9 9 9 7 Leucine rich repeat GPS PF01825.21 PRP85399.1 - 3.9e-08 33.7 4.8 3.9e-08 33.7 4.8 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP85399.1 - 0.0048 17.3 29.7 0.65 10.8 0.2 9.3 8 2 0 8 8 8 1 Leucine Rich Repeat CUE PF02845.16 PRP85399.1 - 0.11 12.2 0.1 0.4 10.4 0.1 2.0 1 0 0 1 1 1 0 CUE domain LRR_6 PF13516.6 PRP85399.1 - 0.28 11.3 37.4 1.5 9.0 0.3 9.7 10 0 0 10 10 10 0 Leucine Rich repeat SAP18 PF06487.12 PRP85399.1 - 1.1 9.4 3.4 0.64 10.2 0.4 2.1 2 1 1 3 3 3 0 Sin3 associated polypeptide p18 (SAP18) TMEM154 PF15102.6 PRP85399.1 - 1.5 8.7 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 0 TMEM154 protein family PAS PF00989.25 PRP85400.1 - 0.037 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold VIT PF08487.10 PRP85401.1 - 5e-32 110.4 0.1 1.3e-31 109.1 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PRP85401.1 - 2.6e-22 79.4 0.0 5.5e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP85401.1 - 4.5e-13 49.8 0.0 1.4e-12 48.2 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 PRP85401.1 - 5.1e-11 42.3 0.2 1.4e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 PRP85401.1 - 1.6e-07 31.9 0.0 8.3e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PRP85401.1 - 0.0001 21.8 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein CobT_C PF11775.8 PRP85401.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain adh_short PF00106.25 PRP85402.1 - 2.6e-23 82.5 0.0 3.5e-22 78.8 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Ank_2 PF12796.7 PRP85402.1 - 7.9e-20 71.2 0.0 3.4e-10 40.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP85402.1 - 1.5e-13 49.6 0.1 0.025 15.1 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PRP85402.1 - 1.2e-12 47.7 0.4 0.00026 21.2 0.0 6.1 5 1 1 6 6 6 3 Ankyrin repeats (many copies) adh_short_C2 PF13561.6 PRP85402.1 - 1.3e-11 44.6 0.0 3.5e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank PF00023.30 PRP85402.1 - 1.4e-09 38.0 0.1 0.0041 17.5 0.0 5.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 PRP85402.1 - 6e-09 36.3 0.8 0.0011 19.5 0.0 5.5 3 3 3 6 6 6 2 Ankyrin repeats (many copies) KR PF08659.10 PRP85402.1 - 5.8e-07 29.6 0.0 2e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 PRP85403.1 - 3.4e-35 121.3 0.0 5.3e-34 117.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP85403.1 - 2.4e-19 69.8 0.0 7.3e-19 68.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP85403.1 - 2.8e-09 37.1 0.1 5.1e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP85403.1 - 0.015 14.7 0.0 0.04 13.4 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 PRP85403.1 - 0.12 11.7 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Beach PF02138.18 PRP85404.1 - 3.4e-115 384.2 0.9 5.8e-115 383.4 0.1 1.7 2 0 0 2 2 2 1 Beige/BEACH domain WD40 PF00400.32 PRP85404.1 - 4.9e-22 77.8 21.7 0.0051 17.6 0.5 7.8 8 0 0 8 8 7 6 WD domain, G-beta repeat PH_BEACH PF14844.6 PRP85404.1 - 9.6e-13 48.1 0.0 3.8e-11 43.0 0.0 2.8 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH ANAPC4_WD40 PF12894.7 PRP85404.1 - 8.8e-12 45.2 1.1 0.00021 21.5 0.1 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP85404.1 - 9.2e-07 28.5 1.7 0.021 14.2 0.0 2.8 1 1 1 3 3 3 3 WD40-like domain Nup160 PF11715.8 PRP85404.1 - 1.6e-05 23.8 5.9 0.007 15.1 0.2 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 PRP85404.1 - 4e-05 23.6 0.0 0.22 11.6 0.0 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 PRP85404.1 - 0.00018 20.2 0.1 0.12 10.9 0.0 2.4 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_3 PF13570.6 PRP85404.1 - 0.00043 20.7 0.3 3.9 8.1 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain VID27 PF08553.10 PRP85404.1 - 0.0013 17.9 0.1 0.041 13.0 0.0 2.7 3 0 0 3 3 3 1 VID27 C-terminal WD40-like domain Hira PF07569.11 PRP85404.1 - 0.0062 16.3 4.4 0.083 12.6 0.1 3.2 4 0 0 4 4 4 1 TUP1-like enhancer of split Mcl1_mid PF12341.8 PRP85404.1 - 0.16 11.3 0.5 2 7.7 0.1 2.2 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region VIT PF08487.10 PRP85405.1 - 1.6e-22 79.8 0.0 3.9e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PRP85405.1 - 7.6e-19 68.2 0.0 1.3e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP85405.1 - 1.7e-09 38.2 0.0 5.7e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 PRP85405.1 - 6e-06 26.1 0.1 1.5e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Tyr-DNA_phospho PF06087.12 PRP85407.1 - 1.1e-56 192.6 1.4 2e-56 191.7 1.4 1.3 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 PRP85407.1 - 2.4e-06 27.5 0.3 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.20 PRP85407.1 - 0.11 12.5 4.8 0.23 11.5 4.8 1.5 1 0 0 1 1 1 0 Ubiquitin interaction motif Pyr_redox_2 PF07992.14 PRP85408.1 - 3.1e-51 174.4 0.1 4.4e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP85408.1 - 7.1e-18 65.0 5.9 4.8e-13 49.5 1.5 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 PRP85408.1 - 1.3e-17 63.5 0.1 3e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PRP85408.1 - 4.3e-11 42.7 0.0 1.9e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.6 PRP85408.1 - 2.6e-10 40.1 0.3 1.1e-08 34.7 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 PRP85408.1 - 4.1e-10 40.1 0.0 1.1e-09 38.7 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal HI0933_like PF03486.14 PRP85408.1 - 0.0017 17.2 0.2 1.2 7.8 0.0 3.6 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.24 PRP85408.1 - 0.0077 15.9 2.5 0.22 11.1 0.0 2.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PRP85408.1 - 0.02 14.2 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase THF_DHG_CYH_C PF02882.19 PRP85408.1 - 0.11 11.8 2.7 2.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 PRP85408.1 - 0.19 12.2 0.4 2.1 8.9 0.5 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 PRP85408.1 - 0.21 10.4 1.0 0.29 10.0 0.2 1.6 1 1 1 2 2 2 0 Tryptophan halogenase Anoctamin PF04547.12 PRP85410.1 - 5.8e-103 345.1 22.2 8.8e-103 344.5 22.2 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PRP85410.1 - 0.00021 21.1 0.0 0.036 13.8 0.0 2.4 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin zf-RING_2 PF13639.6 PRP85411.1 - 8.9e-10 38.7 9.2 1.4e-09 38.1 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP85411.1 - 1.4e-06 28.0 8.6 2.4e-06 27.3 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP85411.1 - 2e-05 24.3 9.5 3.6e-05 23.5 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP85411.1 - 4e-05 23.3 7.0 8.2e-05 22.3 7.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 PRP85411.1 - 5e-05 23.2 8.4 7.9e-05 22.5 8.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PRP85411.1 - 7.9e-05 22.9 10.9 0.00022 21.5 10.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PRP85411.1 - 0.00012 21.8 6.3 0.0002 21.1 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP85411.1 - 0.00066 19.6 3.7 0.0017 18.3 3.8 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 PRP85411.1 - 0.0021 17.7 8.0 0.0036 16.9 8.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 PRP85411.1 - 0.0033 17.4 4.2 0.0077 16.3 4.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PRP85411.1 - 0.0038 17.0 7.9 0.006 16.4 7.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C2HC_2 PF13913.6 PRP85411.1 - 0.035 14.0 1.8 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 PRP85411.1 - 0.4 10.8 5.2 0.77 9.9 5.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger FANCL_C PF11793.8 PRP85411.1 - 0.41 10.9 11.6 7.7 6.8 11.6 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 PRP85411.1 - 0.64 9.9 3.6 1.1 9.1 3.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 PRP85411.1 - 0.73 10.0 8.4 1.4 9.1 8.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 PRP85411.1 - 1.6 8.7 9.5 2.9 7.8 9.5 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 PRP85411.1 - 6.5 7.0 10.8 12 6.1 10.8 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 PRP85411.1 - 9.4 6.4 10.9 11 6.2 8.1 2.5 2 1 0 2 2 2 0 Zinc-finger AMP-binding PF00501.28 PRP85412.1 - 8.9e-39 133.3 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PQQ_3 PF13570.6 PRP85412.1 - 7.3e-27 93.1 1.8 4.1e-05 23.9 0.0 8.7 8 0 0 8 8 8 5 PQQ-like domain PQQ PF01011.21 PRP85412.1 - 9.7e-17 60.0 0.8 0.00046 20.0 0.0 5.3 5 0 0 5 5 5 3 PQQ enzyme repeat PQQ_2 PF13360.6 PRP85412.1 - 5.2e-16 58.9 0.0 2.1e-09 37.3 0.0 2.8 1 1 1 2 2 2 2 PQQ-like domain Reg_prop PF07494.11 PRP85412.1 - 0.02 15.1 0.1 1.9 9.0 0.0 3.8 2 0 0 2 2 2 0 Two component regulator propeller RasGAP PF00616.19 PRP85413.1 - 2.1e-10 40.7 0.8 9.4e-06 25.5 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase SCP2 PF02036.17 PRP85415.1 - 1.6e-29 102.4 1.1 2.2e-29 101.9 1.1 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 PRP85415.1 - 2.2e-07 31.2 0.1 3e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal zf-HC5HC2H_2 PF13832.6 PRP85416.1 - 3.7e-25 88.2 8.8 3.7e-25 88.2 8.8 4.6 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PRP85416.1 - 3.2e-17 62.6 5.8 3.2e-17 62.6 5.8 5.7 5 1 0 5 5 4 3 PHD-like zinc-binding domain PHD PF00628.29 PRP85416.1 - 4.1e-17 61.8 21.7 1.2e-10 41.1 5.6 5.6 5 1 0 5 5 4 3 PHD-finger PHD_2 PF13831.6 PRP85416.1 - 4e-14 51.9 28.3 1.5e-13 50.0 2.9 5.5 5 0 0 5 5 5 2 PHD-finger EPL1 PF10513.9 PRP85416.1 - 8.6e-08 32.7 5.6 8.6e-08 32.7 5.6 3.8 2 2 0 2 2 1 1 Enhancer of polycomb-like zf-PHD-like PF15446.6 PRP85416.1 - 0.0017 18.0 1.9 0.0017 18.0 1.9 6.3 8 1 0 8 8 8 1 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 PRP85416.1 - 0.0082 16.4 2.0 0.0082 16.4 2.0 6.1 8 0 0 8 8 6 2 C1 domain FYVE_2 PF02318.16 PRP85416.1 - 0.014 15.6 4.3 0.014 15.6 4.3 4.9 5 0 0 5 5 5 0 FYVE-type zinc finger C1_1 PF00130.22 PRP85416.1 - 0.02 14.8 0.8 0.02 14.8 0.8 5.4 5 2 1 6 6 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF5601 PF18151.1 PRP85416.1 - 0.12 12.8 0.6 0.59 10.5 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF5601) DUF1388 PF07142.12 PRP85416.1 - 0.16 12.0 8.1 0.027 14.4 3.3 2.2 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) Importin_rep_6 PF18829.1 PRP85417.1 - 0.14 12.3 0.4 0.24 11.6 0.4 1.3 1 0 0 1 1 1 0 Importin repeat 6 Cu_amine_oxid PF01179.20 PRP85418.1 - 4.6e-138 460.6 0.0 8e-138 459.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 PRP85418.1 - 1e-15 58.0 0.2 3.2e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 PRP85418.1 - 0.043 14.0 0.1 0.25 11.6 0.0 2.4 2 1 0 2 2 2 0 Copper amine oxidase, N2 domain FlgM PF04316.13 PRP85419.1 - 0.034 14.5 0.4 0.034 14.5 0.4 1.7 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM EF-hand_9 PF14658.6 PRP85419.1 - 0.091 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Kinesin PF00225.23 PRP85420.1 - 8.8e-101 337.1 0.4 8.8e-101 337.1 0.4 4.1 3 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 PRP85420.1 - 5.2e-46 156.3 0.0 5.2e-46 156.3 0.0 3.4 3 0 0 3 3 3 1 Microtubule binding Sec7 PF01369.20 PRP85423.1 - 3.3e-52 176.8 0.1 6.7e-52 175.8 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 PRP85423.1 - 6.1e-18 65.3 0.2 6.5e-07 29.8 0.0 3.8 3 0 0 3 3 3 3 PH domain DEP PF00610.21 PRP85423.1 - 3.1e-15 56.0 0.1 6.7e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ras PF00071.22 PRP85423.1 - 6e-14 52.0 0.2 2.1e-13 50.2 0.2 2.0 1 1 0 1 1 1 1 Ras family PH_11 PF15413.6 PRP85423.1 - 0.0054 17.1 0.0 0.16 12.4 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain Roc PF08477.13 PRP85423.1 - 0.006 16.8 0.1 0.03 14.5 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP85423.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family SAS-6_N PF16531.5 PRP85424.1 - 1.4e-19 70.4 1.3 3.3e-19 69.3 0.2 2.2 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal DASH_Dad1 PF08649.10 PRP85424.1 - 0.02 15.1 2.0 2.1 8.6 0.1 3.1 2 0 0 2 2 2 0 DASH complex subunit Dad1 YbaJ PF10757.9 PRP85424.1 - 0.1 13.2 2.6 0.35 11.4 0.3 2.9 2 1 0 3 3 3 0 Biofilm formation regulator YbaJ Filament PF00038.21 PRP85424.1 - 2.3 7.7 51.9 2 7.9 8.5 3.2 1 1 1 3 3 3 0 Intermediate filament protein F-box PF00646.33 PRP85426.1 - 0.00044 20.1 1.3 0.00058 19.7 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP85426.1 - 0.00082 19.2 0.1 0.0034 17.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like Profilin PF00235.19 PRP85426.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 0 Profilin F5_F8_type_C PF00754.25 PRP85426.1 - 0.013 15.6 0.5 0.038 14.1 0.5 1.8 1 0 0 1 1 1 0 F5/8 type C domain FmiP_Thoc5 PF09766.9 PRP85426.1 - 0.07 12.4 0.9 0.17 11.2 0.1 1.8 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Peptidase_C2 PF00648.21 PRP85427.1 - 5.6e-70 235.7 0.1 8.4e-70 235.1 0.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 PRP85427.1 - 4.3e-20 72.4 0.0 1.6e-19 70.5 0.0 2.1 1 0 0 1 1 1 1 Calpain large subunit, domain III DUF4490 PF14892.6 PRP85427.1 - 3.9e-07 30.1 2.0 4.7e-07 29.8 0.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4490) FancD2 PF14631.6 PRP85427.1 - 7e-07 27.1 9.1 8.1e-05 20.3 2.2 2.2 1 1 1 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 PRP85427.1 - 0.002 18.4 0.6 0.0074 16.6 0.6 1.9 1 0 0 1 1 1 1 FANCI solenoid 2 cobW PF02492.19 PRP85428.1 - 1e-52 178.3 0.4 1.5e-52 177.7 0.4 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PRP85428.1 - 4.2e-07 29.8 0.0 7.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 PRP85428.1 - 0.00039 20.4 0.2 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 PRP85428.1 - 0.0013 19.1 0.4 0.011 16.0 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP85428.1 - 0.0028 18.1 0.0 0.21 12.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 PRP85428.1 - 0.0028 17.7 0.1 0.0071 16.4 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PRP85428.1 - 0.038 13.4 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Viral_helicase1 PF01443.18 PRP85428.1 - 0.079 12.7 0.1 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 PRP85428.1 - 0.095 12.5 0.6 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PRP85428.1 - 0.1 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 PRP85428.1 - 0.11 11.5 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MeaB PF03308.16 PRP85428.1 - 0.14 11.2 0.4 0.3 10.0 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 PRP85428.1 - 0.15 12.6 0.2 0.34 11.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 PRP85428.1 - 0.15 12.0 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 PRP85428.1 - 0.17 11.6 0.4 1.1 8.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PRP85428.1 - 0.17 11.9 0.1 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PRP85428.1 - 1.4 9.3 4.6 3.5 8.1 4.6 1.9 1 1 0 1 1 1 0 AAA domain RasGEF PF00617.19 PRP85429.1 - 2e-45 155.2 0.4 5e-45 153.9 0.4 1.7 1 0 0 1 1 1 1 RasGEF domain eIF3_subunit PF08597.10 PRP85429.1 - 1e-34 120.6 15.4 1e-34 120.6 15.4 2.4 2 1 1 3 3 3 1 Translation initiation factor eIF3 subunit RasGEF_N PF00618.20 PRP85429.1 - 7.2e-13 48.7 0.1 3.4e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif SlyX PF04102.12 PRP85429.1 - 4.8 7.9 7.7 3.2 8.4 0.8 4.0 4 0 0 4 4 4 0 SlyX Pkinase_Tyr PF07714.17 PRP85430.1 - 5.3e-50 170.1 0.1 7.9e-50 169.5 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85430.1 - 2.3e-33 115.7 0.1 4.1e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP85430.1 - 4.2e-08 33.6 3.1 4.2e-08 33.6 3.1 2.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Beta_helix PF13229.6 PRP85430.1 - 0.00013 21.9 11.4 0.00013 21.9 11.4 4.7 2 1 1 3 3 3 1 Right handed beta helix region GAS2 PF02187.17 PRP85431.1 - 1.3e-11 44.4 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CH PF00307.31 PRP85431.1 - 6.4e-10 39.2 0.4 1.2e-09 38.4 0.4 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 PRP85431.1 - 2.2e-07 31.0 0.5 5.3e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 CDC24 Calponin CAMSAP_CH PF11971.8 PRP85431.1 - 6.9e-06 25.8 0.2 1.8e-05 24.5 0.2 1.7 2 0 0 2 2 2 1 CAMSAP CH domain PAS_9 PF13426.7 PRP85432.1 - 2.3e-18 66.4 0.3 8.1e-18 64.6 0.1 2.1 2 0 0 2 2 2 1 PAS domain RasGAP PF00616.19 PRP85432.1 - 7.9e-11 42.1 0.1 0.00027 20.7 0.1 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase SAM_2 PF07647.17 PRP85432.1 - 2.4e-05 24.3 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP85432.1 - 2.7e-05 24.5 0.0 6.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAS_3 PF08447.12 PRP85432.1 - 0.012 15.9 0.0 0.053 13.8 0.0 2.1 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.10 PRP85432.1 - 0.074 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 PRP85432.1 - 0.093 12.7 0.1 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 PAS fold Cellulase PF00150.18 PRP85434.1 - 3.6e-24 85.7 8.3 4.8e-24 85.3 8.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_S8e PF01201.22 PRP85435.1 - 9.4e-51 171.6 0.5 1.3e-50 171.2 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Fz PF01392.22 PRP85436.1 - 0.13 12.9 7.8 0.66 10.6 7.5 2.3 1 1 0 1 1 1 0 Fz domain Sacchrp_dh_C PF16653.5 PRP85437.1 - 1.1e-45 156.8 0.0 2e-45 156.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 PRP85437.1 - 8.6e-28 97.3 0.0 1.6e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 PRP85437.1 - 2.9e-22 79.3 0.5 5.8e-22 78.3 0.5 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 PRP85437.1 - 5.9e-07 29.0 0.0 0.00086 18.7 0.0 3.2 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 PRP85437.1 - 0.00064 19.8 0.6 0.0019 18.3 0.5 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF2184 PF09950.9 PRP85437.1 - 0.011 15.2 0.0 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) G8 PF10162.9 PRP85439.1 - 1.7e-05 24.9 2.5 0.00077 19.5 0.3 2.9 2 1 1 3 3 3 2 G8 domain Amnionless PF14828.6 PRP85439.1 - 0.0042 16.0 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Amnionless Rap_GAP PF02145.15 PRP85440.1 - 1.2e-60 204.2 0.0 2.1e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Zip PF02535.22 PRP85440.1 - 1.9 7.6 4.0 3.6 6.7 4.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter tRNA-synt_1c PF00749.21 PRP85440.1 - 5.7 5.7 12.2 14 4.5 12.2 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Glyco_hydro81C PF17652.1 PRP85441.1 - 1.2e-70 238.6 0.1 1.9e-70 237.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 PRP85441.1 - 9.4e-40 136.7 7.4 1.7e-39 135.9 7.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain LRR_8 PF13855.6 PRP85442.1 - 9.1e-18 63.8 62.8 0.00028 20.6 0.2 9.5 5 3 4 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 PRP85442.1 - 3.8e-17 62.1 82.2 7.4e-07 29.4 7.5 12.0 6 3 8 14 14 14 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP85442.1 - 0.13 11.8 11.1 0.51 9.8 0.8 3.9 2 1 3 5 5 5 0 Leucine-rich repeat LRR_1 PF00560.33 PRP85442.1 - 2.9 8.8 45.6 9.7 7.2 0.0 13.3 11 4 0 11 11 11 0 Leucine Rich Repeat Oxysterol_BP PF01237.18 PRP85443.1 - 6.5e-84 281.9 2.3 2.7e-82 276.6 0.1 2.8 2 1 0 2 2 2 1 Oxysterol-binding protein PH PF00169.29 PRP85443.1 - 2e-11 44.3 0.2 5.7e-11 42.9 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP85443.1 - 0.0038 17.6 0.2 0.011 16.1 0.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DBC1 PF14443.6 PRP85443.1 - 0.15 12.0 0.4 0.67 9.9 0.0 2.1 1 1 1 2 2 2 0 DBC1 AhpC-TSA_2 PF13911.6 PRP85444.1 - 2.4e-16 59.9 0.0 3.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 PRP85444.1 - 0.00037 20.4 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Suppressor_P21 PF11479.8 PRP85444.1 - 0.19 12.0 0.0 6.8 7.0 0.0 2.2 2 0 0 2 2 2 0 RNA silencing suppressor P21 C-terminal domain RRM_1 PF00076.22 PRP85446.1 - 1e-18 66.9 0.2 6.2e-08 32.4 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glycos_transf_4 PF00953.21 PRP85447.1 - 1.8e-33 115.8 16.9 1.8e-33 115.8 16.9 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 4 PROCN PF08083.11 PRP85448.1 - 1.9e-233 774.5 6.7 3.2e-233 773.8 6.7 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 PRP85448.1 - 2.2e-124 413.6 1.0 3.9e-124 412.8 1.0 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 PRP85448.1 - 2.1e-88 294.3 2.0 5.6e-88 292.9 2.0 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 PRP85448.1 - 3.9e-85 283.4 1.7 9e-85 282.2 1.7 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 PRP85448.1 - 1.3e-71 238.9 0.0 2.6e-71 238.0 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 PRP85448.1 - 3.1e-48 162.8 2.0 4.7e-48 162.2 0.5 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 PRP85448.1 - 3.8e-48 161.8 0.6 1.6e-47 159.7 0.6 2.2 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF1016_N PF17761.1 PRP85448.1 - 0.048 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 DUF1016 N-terminal domain JAB PF01398.21 PRP85448.1 - 0.082 12.9 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HEPN_Swt1 PF18731.1 PRP85448.1 - 8 6.8 6.5 8.6 6.8 0.1 3.8 4 0 0 4 4 4 0 Swt1-like HEPN GPCR_chapero_1 PF11904.8 PRP85449.1 - 4.8e-27 95.2 0.5 6e-17 62.0 0.0 2.2 1 1 1 2 2 2 2 GPCR-chaperone Ank_5 PF13857.6 PRP85449.1 - 6.5e-09 35.9 0.0 3.6e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85449.1 - 2.7e-07 30.3 0.2 0.00084 19.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PRP85449.1 - 5.5e-07 29.8 0.3 2.5e-05 24.5 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 PRP85449.1 - 8.5e-07 29.5 0.0 2.7e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85449.1 - 1.7e-05 25.2 0.0 0.00025 21.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 PRP85450.1 - 1.6e-11 44.7 0.0 1.8e-10 41.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP85450.1 - 1.3e-10 41.3 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP85450.1 - 9.9e-09 35.7 0.0 4.6e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 PRP85450.1 - 6.3e-08 33.3 0.0 1.1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP85450.1 - 9.6e-08 32.0 0.0 2.6e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 PRP85450.1 - 5.5e-05 22.7 0.0 9.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.11 PRP85450.1 - 0.00015 21.5 0.0 0.00078 19.2 0.0 2.1 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 PRP85450.1 - 0.061 12.6 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Chorein_N PF12624.7 PRP85451.1 - 9.9e-19 67.6 0.5 9.9e-19 67.6 0.5 3.6 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 PRP85451.1 - 9.3e-13 48.3 0.1 1.8e-08 34.6 0.0 2.6 1 1 1 2 2 2 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 PRP85451.1 - 5.1e-08 32.9 1.8 6e-08 32.7 0.1 2.1 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Tape_meas_lam_C PF09718.10 PRP85451.1 - 0.058 13.5 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) SbcD_C PF12320.8 PRP85451.1 - 0.88 9.9 5.5 0.62 10.4 0.5 3.2 4 0 0 4 4 4 0 Type 5 capsule protein repressor C-terminal domain Bac_rhodopsin PF01036.18 PRP85452.1 - 5.2e-39 134.1 20.1 6.7e-39 133.8 20.1 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF5373 PF17343.2 PRP85452.1 - 0.0079 16.1 0.6 0.0079 16.1 0.6 2.5 2 1 1 3 3 3 1 Family of unknown function (DUF5373) DUF5592 PF17332.2 PRP85452.1 - 0.66 10.6 0.1 0.66 10.6 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5592) Tmemb_170 PF10190.9 PRP85452.1 - 0.71 10.3 10.9 0.065 13.6 4.5 2.3 2 0 0 2 2 2 0 Putative transmembrane protein 170 COX6C PF02937.15 PRP85452.1 - 3.6 7.8 4.8 16 5.7 1.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIc Oxysterol_BP PF01237.18 PRP85453.1 - 2.4e-110 368.9 0.1 3.4e-110 368.4 0.1 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Motile_Sperm PF00635.26 PRP85454.1 - 1.6e-23 82.6 0.1 2.5e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF3584 PF12128.8 PRP85454.1 - 0.0031 15.1 4.3 0.0043 14.7 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TolA_bind_tri PF16331.5 PRP85454.1 - 0.004 17.2 3.0 0.0077 16.3 3.0 1.4 1 0 0 1 1 1 1 TolA binding protein trimerisation TPR_MLP1_2 PF07926.12 PRP85454.1 - 0.0075 16.3 9.8 0.014 15.5 9.9 1.4 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 PRP85454.1 - 0.011 15.0 2.4 0.017 14.5 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HMMR_N PF15905.5 PRP85454.1 - 0.014 14.9 3.7 0.02 14.4 3.7 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 PRP85454.1 - 0.021 13.9 3.9 0.03 13.4 3.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 PRP85454.1 - 0.033 14.6 0.7 0.089 13.2 0.7 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 PRP85454.1 - 0.04 14.0 0.9 0.069 13.2 0.9 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Csm1_N PF18504.1 PRP85454.1 - 0.31 11.4 6.0 0.37 11.1 4.5 1.9 2 0 0 2 2 1 0 Csm1 N-terminal domain DUF3552 PF12072.8 PRP85454.1 - 0.83 9.0 7.0 1.4 8.3 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) EGF_2 PF07974.13 PRP85455.1 - 0.15 12.5 6.1 0.32 11.4 6.1 1.5 1 0 0 1 1 1 0 EGF-like domain PGA_cap PF09587.10 PRP85455.1 - 0.2 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap CYYR1 PF10873.8 PRP85455.1 - 1.8 9.0 4.9 4.7 7.7 4.9 1.7 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 COX7C PF02935.16 PRP85455.1 - 1.9 8.8 9.5 2.8 8.3 0.0 3.6 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc DUF4246 PF14033.6 PRP85456.1 - 2.1e-131 439.2 0.2 2.5e-131 438.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Nab2p_Zf1 PF18260.1 PRP85456.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 DUF5336 PF17270.2 PRP85457.1 - 0.034 13.8 0.1 0.07 12.8 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5336) Vmethyltransf PF01660.17 PRP85457.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Viral methyltransferase DUF2207 PF09972.9 PRP85457.1 - 0.35 9.6 5.8 4.3 6.0 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Hemerythrin PF01814.23 PRP85458.1 - 1.2e-09 38.9 4.1 2.4e-09 37.9 4.1 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PdaC PF13739.6 PRP85458.1 - 0.24 12.4 1.9 0.37 11.8 0.7 1.9 1 1 1 2 2 2 0 Deacetylase PdaC Hemerythrin PF01814.23 PRP85459.1 - 1.1e-10 42.3 7.5 2.1e-10 41.4 7.5 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain TCTP PF00838.17 PRP85459.1 - 0.047 14.0 0.7 0.082 13.2 0.2 1.5 1 1 0 1 1 1 0 Translationally controlled tumour protein UPF0506 PF11703.8 PRP85460.1 - 0.11 12.8 0.1 0.19 12.2 0.1 1.2 1 0 0 1 1 1 0 UPF0506 PPR_2 PF13041.6 PRP85461.1 - 1.9e-12 47.2 0.9 0.033 14.4 0.0 5.5 4 2 3 7 7 7 4 PPR repeat family PPR_3 PF13812.6 PRP85461.1 - 9.3e-06 25.6 0.2 3 8.0 0.1 4.5 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 PRP85461.1 - 3e-05 24.0 0.4 0.41 11.0 0.0 4.9 5 0 0 5 5 5 2 PPR repeat DUF5069 PF16798.5 PRP85461.1 - 0.0067 16.6 0.2 0.15 12.3 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF5069) BCS1_N PF08740.11 PRP85462.1 - 8.8e-20 71.5 0.5 8.8e-20 71.5 0.5 1.5 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 PRP85462.1 - 5e-17 62.6 0.0 1.4e-16 61.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 PRP85462.1 - 7.5e-06 25.3 0.0 1.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 PRP85462.1 - 0.0014 19.0 0.0 0.0098 16.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DRY_EERY PF09750.9 PRP85462.1 - 0.002 18.4 1.4 0.0052 17.1 1.4 1.6 1 0 0 1 1 1 1 Alternative splicing regulator AAA_25 PF13481.6 PRP85462.1 - 0.0079 15.8 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PRP85462.1 - 0.0082 16.4 0.1 0.27 11.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PRP85462.1 - 0.01 15.4 0.1 0.66 9.5 0.0 2.6 1 1 1 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 PRP85462.1 - 0.015 15.7 0.0 0.056 13.8 0.0 2.1 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 PRP85462.1 - 0.018 15.5 0.0 0.052 14.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 PRP85462.1 - 0.043 14.3 5.1 0.21 12.0 1.9 2.8 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 PRP85462.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 PRP85462.1 - 0.067 13.2 0.0 0.3 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 PRP85462.1 - 0.068 12.9 0.5 6.4 6.5 0.6 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP85462.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PRP85462.1 - 0.12 12.4 0.0 0.39 10.8 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase DDRGK PF09756.9 PRP85462.1 - 1.6 8.3 14.8 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 DDRGK domain Herpes_LMP1 PF05297.11 PRP85463.1 - 0.84 8.8 2.5 0.97 8.6 2.5 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) WWE PF02825.20 PRP85464.1 - 2.5e-09 37.6 1.1 6.6e-09 36.2 1.1 1.8 1 0 0 1 1 1 1 WWE domain Linker_histone PF00538.19 PRP85464.1 - 1.5e-05 25.3 0.2 4e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family VIGSSK PF14773.6 PRP85464.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.7 2 1 0 2 2 2 0 Helicase-associated putative binding domain, C-terminal DUF4692 PF15763.5 PRP85464.1 - 0.93 9.9 5.8 1.2 9.6 4.7 1.7 2 1 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) RR_TM4-6 PF06459.12 PRP85464.1 - 2.4 7.9 12.0 3.2 7.5 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 PRP85464.1 - 2.8 6.0 8.2 3.4 5.7 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 PRP85464.1 - 2.9 6.5 8.8 3.4 6.3 8.8 1.1 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 PRP85464.1 - 4 6.2 10.7 5.6 5.8 10.7 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein MMR1 PF08505.10 PRP85464.1 - 8.6 6.6 15.0 14 5.8 14.6 1.4 1 1 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Sec62 PF03839.16 PRP85464.1 - 9.8 5.6 12.4 15 5.0 12.4 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 TPR_12 PF13424.6 PRP85465.1 - 5.3e-12 45.9 7.5 0.012 15.9 0.0 6.1 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 PRP85465.1 - 3.8e-09 36.1 3.5 0.019 14.8 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP85465.1 - 5e-08 32.4 3.5 0.00052 19.7 0.0 5.6 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85465.1 - 1.1e-07 31.4 3.2 0.021 14.9 0.0 5.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP85465.1 - 5.9e-07 29.1 0.4 0.0074 16.2 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP85465.1 - 2.3e-06 27.2 0.0 2e-05 24.1 0.0 2.2 1 1 1 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 PRP85465.1 - 0.0045 17.7 1.2 35 5.6 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 PRP85465.1 - 0.017 15.7 1.7 3.4 8.5 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 PRP85465.1 - 0.04 13.6 0.0 0.22 11.2 0.0 2.2 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_8 PF13181.6 PRP85465.1 - 0.67 10.3 2.5 23 5.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 PRP85465.1 - 1.5 8.2 5.2 7.9 5.8 0.2 2.6 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP Phosphonate-bd PF12974.7 PRP85466.1 - 1.6e-07 31.2 0.4 4e-07 29.9 0.3 1.8 2 0 0 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 PRP85466.1 - 2.4e-06 27.7 0.1 3.9e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like ChiC PF06483.11 PRP85466.1 - 0.014 15.3 0.2 0.1 12.5 0.0 2.4 3 0 0 3 3 3 0 Chitinase C OpuAC PF04069.12 PRP85466.1 - 0.015 14.9 0.1 0.044 13.3 0.0 1.7 1 1 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system SBP_bac_3 PF00497.20 PRP85466.1 - 0.051 13.0 0.1 0.3 10.5 0.0 2.1 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Fucosidase_C PF16757.5 PRP85466.1 - 0.15 12.6 0.1 0.3 11.7 0.1 1.5 1 0 0 1 1 1 0 Alpha-L-fucosidase C-terminal domain EGF_2 PF07974.13 PRP85467.1 - 0.0088 16.4 7.0 0.017 15.5 7.0 1.4 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 PRP85467.1 - 1.5 8.9 4.7 3.6 7.7 4.7 1.6 1 0 0 1 1 1 0 Tenascin EGF domain EPL1 PF10513.9 PRP85468.1 - 0.096 13.1 7.9 5.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF1682 PF07946.14 PRP85468.1 - 0.21 10.8 18.1 0.34 10.1 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 PRP85468.1 - 1.1 9.1 14.5 2.1 8.1 14.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMEM214 PF10151.9 PRP85468.1 - 5.7 5.3 12.3 7.9 4.8 12.3 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Peptidase_S49_N PF08496.10 PRP85468.1 - 9.1 6.3 13.2 29 4.7 13.2 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_hydro_16 PF00722.21 PRP85469.1 - 1.1e-07 31.5 0.2 3.3e-07 29.9 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Carb_bind PF10645.9 PRP85469.1 - 2.1e-07 31.1 23.4 3.5e-07 30.3 16.2 3.3 2 1 1 3 3 3 2 Carbohydrate binding Dicty_REP PF05086.12 PRP85469.1 - 1.8 6.5 3.8 2.3 6.1 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 PRP85469.1 - 2.1 8.3 30.5 0.91 9.5 21.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DNA_repr_REX1B PF14966.6 PRP85472.1 - 4e-15 56.2 8.6 5.9e-15 55.7 3.9 2.7 1 1 1 2 2 2 1 DNA repair REX1-B Lyase_1 PF00206.20 PRP85473.1 - 2.6e-51 174.9 0.0 3.5e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 PRP85473.1 - 7.2e-46 155.0 0.1 1.4e-45 154.1 0.1 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal P2X_receptor PF00864.19 PRP85474.1 - 1.8e-58 198.4 2.5 7.1e-29 101.0 0.1 2.0 1 1 1 2 2 2 2 ATP P2X receptor DUF1746 PF08508.10 PRP85475.1 - 1.2e-06 28.8 15.6 1.1e-05 25.7 15.6 1.9 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Ribosomal_L3 PF00297.22 PRP85476.1 - 5.5e-16 58.5 3.9 7.4e-15 54.8 3.4 2.2 1 1 1 2 2 2 1 Ribosomal protein L3 MVL PF12151.8 PRP85476.1 - 0.044 13.6 0.2 0.35 10.8 0.0 2.3 2 0 0 2 2 2 0 Mannan-binding protein DUF846 PF05832.12 PRP85477.1 - 8.5e-40 136.0 16.4 9.7e-40 135.8 16.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) YtpI PF14007.6 PRP85477.1 - 1.6 8.9 9.2 0.76 10.0 0.3 2.2 2 0 0 2 2 2 0 YtpI-like protein UPF0242 PF06785.11 PRP85478.1 - 0.0056 16.8 15.3 0.0056 16.8 15.3 10.0 2 1 8 10 10 10 3 Uncharacterised protein family (UPF0242) N-terminus DapH_N PF08503.10 PRP85478.1 - 0.043 14.0 1.7 1.1 9.5 0.1 3.5 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal DUF998 PF06197.13 PRP85479.1 - 0.00027 20.6 2.9 0.00037 20.1 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF1129 PF06570.11 PRP85479.1 - 0.01 15.3 1.7 0.042 13.3 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) RicinB_lectin_2 PF14200.6 PRP85481.1 - 8e-10 39.3 20.9 0.00049 20.8 0.5 5.8 3 2 3 6 6 6 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 PRP85481.1 - 0.027 14.7 10.7 6.2 7.1 0.0 4.7 3 2 1 5 5 5 0 Ricin-type beta-trefoil lectin domain Fer2_BFD PF04324.15 PRP85481.1 - 0.097 13.0 0.1 30 5.1 0.0 2.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF870 PF05912.11 PRP85481.1 - 0.27 11.3 1.9 5.1 7.1 0.3 2.6 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) NAM-associated PF14303.6 PRP85481.1 - 6.8 7.4 5.9 12 6.6 5.9 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain HpaB_N PF11794.8 PRP85482.1 - 0.034 13.8 0.0 0.037 13.7 0.0 1.0 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal ORMDL PF04061.14 PRP85483.1 - 0.12 12.2 2.3 0.12 12.2 0.5 1.8 1 1 1 2 2 2 0 ORMDL family Thioredoxin_8 PF13905.6 PRP85484.1 - 3.4e-29 101.0 0.0 4.6e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PRP85484.1 - 5.4e-10 39.2 0.1 3.9e-07 30.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 PRP85484.1 - 3.1e-08 33.5 0.0 4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PRP85484.1 - 3e-07 30.4 0.0 4.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 PRP85484.1 - 6.3e-07 29.8 0.0 1.5e-06 28.6 0.0 1.6 1 1 1 2 2 2 1 Thioredoxin-like domain Glutaredoxin PF00462.24 PRP85484.1 - 0.0018 18.5 0.0 0.034 14.4 0.0 2.5 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 PRP85484.1 - 0.011 15.6 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin SCO1-SenC PF02630.14 PRP85484.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 2 0 0 2 2 2 0 SCO1/SenC Thioredoxin_7 PF13899.6 PRP85484.1 - 0.043 14.0 0.0 0.19 11.9 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like EXS PF03124.14 PRP85485.1 - 1.7e-68 231.4 32.6 1.7e-68 231.4 32.6 1.4 2 0 0 2 2 2 1 EXS family DUF4999 PF16390.5 PRP85485.1 - 0.08 13.2 0.2 0.21 11.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function AMPK1_CBM PF16561.5 PRP85486.1 - 2.4e-33 114.2 0.0 3.8e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 PRP85486.1 - 2e-19 69.6 3.1 3.9e-19 68.7 3.1 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain PAN_4 PF14295.6 PRP85487.1 - 2.2e-66 219.6 112.4 2e-08 34.0 4.5 10.6 10 0 0 10 10 10 10 PAN domain PAN_1 PF00024.26 PRP85487.1 - 7.4e-34 115.6 68.5 0.00035 20.5 1.1 10.3 9 1 1 10 10 10 10 PAN domain LBP_BPI_CETP_C PF02886.17 PRP85487.1 - 9e-30 103.9 0.2 1.9e-29 102.8 0.0 1.5 2 0 0 2 2 2 1 LBP / BPI / CETP family, C-terminal domain PAN_2 PF08276.11 PRP85487.1 - 4.3e-19 68.4 90.3 0.0059 16.7 4.7 10.4 10 0 0 10 10 10 9 PAN-like domain LBP_BPI_CETP PF01273.25 PRP85487.1 - 4.9e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain PAN_3 PF08277.12 PRP85487.1 - 0.0012 18.6 77.9 0.11 12.3 1.9 10.4 10 0 0 10 10 10 6 PAN-like domain MT-A70 PF05063.14 PRP85487.1 - 0.0076 16.2 9.1 7.4 6.5 0.0 7.0 9 0 0 9 9 9 1 MT-A70 Transglycosylas PF06737.14 PRP85487.1 - 0.24 12.1 13.3 6.9 7.4 1.5 4.1 4 0 0 4 4 4 0 Transglycosylase-like domain WD40 PF00400.32 PRP85488.1 - 1.2e-17 63.9 2.4 0.00031 21.5 0.5 5.9 5 1 1 6 6 6 4 WD domain, G-beta repeat Pkinase PF00069.25 PRP85489.1 - 3.4e-64 216.8 0.0 4.8e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85489.1 - 2.5e-28 99.1 0.0 4.3e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP85489.1 - 0.0044 17.0 0.0 0.019 14.9 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP85489.1 - 0.013 15.1 0.2 0.023 14.3 0.2 1.3 1 0 0 1 1 1 0 RIO1 family BSP_II PF05432.11 PRP85490.1 - 5.2 6.7 35.9 11 5.7 35.9 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CSG2 PF16965.5 PRP85490.1 - 7.5 5.4 5.0 17 4.2 3.6 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator GRIP PF01465.20 PRP85491.1 - 5.1e-10 39.1 0.2 1.3e-09 37.8 0.2 1.8 1 0 0 1 1 1 1 GRIP domain Jnk-SapK_ap_N PF09744.9 PRP85491.1 - 1.7e-05 25.1 21.8 1.7e-05 25.1 21.8 11.4 4 2 5 10 10 10 1 JNK_SAPK-associated protein-1 Bap31_Bap29_C PF18035.1 PRP85491.1 - 0.0026 17.7 3.1 0.0026 17.7 3.1 12.3 11 4 4 15 15 15 1 Bap31/Bap29 cytoplasmic coiled-coil domain TPR_MLP1_2 PF07926.12 PRP85491.1 - 0.0031 17.6 23.2 0.0031 17.6 23.2 12.7 4 2 6 11 11 11 4 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 PRP85491.1 - 0.009 16.2 9.0 0.009 16.2 9.0 16.3 8 4 7 16 16 16 2 ABC transporter C-terminal domain Polyoma_agno PF01736.16 PRP85492.1 - 0.13 12.0 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Polyomavirus agnoprotein Aldo_ket_red PF00248.21 PRP85493.1 - 1.7e-78 263.8 0.0 1.9e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HEAT PF02985.22 PRP85494.1 - 1.1e-09 37.7 2.0 0.015 15.5 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 PRP85494.1 - 4.8e-07 30.1 0.0 0.035 14.5 0.0 4.6 2 2 1 4 4 4 2 HEAT repeats CLASP_N PF12348.8 PRP85494.1 - 0.00012 21.8 2.8 0.00019 21.1 0.0 2.7 3 0 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 PRP85494.1 - 0.00084 19.4 5.1 0.12 12.5 0.2 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PRP85494.1 - 0.0014 17.3 5.9 0.013 14.1 0.5 2.8 2 1 0 2 2 2 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 PRP85494.1 - 0.004 17.7 0.4 2.2 8.9 0.0 4.2 4 1 0 5 5 5 1 Vacuolar 14 Fab1-binding region SOGA PF11365.8 PRP85494.1 - 0.13 13.4 7.5 0.62 11.2 0.5 2.9 2 0 0 2 2 2 0 Protein SOGA LisH PF08513.11 PRP85494.1 - 0.3 11.1 1.2 1.1 9.4 0.2 2.3 2 0 0 2 2 2 0 LisH DUF4254 PF14063.6 PRP85494.1 - 0.47 10.3 3.3 0.52 10.1 0.8 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4254) PKcGMP_CC PF16808.5 PRP85494.1 - 1.8 8.5 4.9 0.39 10.6 0.6 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase KASH_CCD PF14662.6 PRP85494.1 - 3.5 7.4 12.6 3.4 7.4 0.1 3.5 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF724 PF05266.14 PRP85494.1 - 3.9 7.3 7.4 5.3 6.8 2.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF724) SPX PF03105.19 PRP85495.1 - 1.1e-32 114.5 6.0 5.5e-17 62.8 4.4 3.1 1 1 1 2 2 2 2 SPX domain zf-C3HC4_4 PF15227.6 PRP85495.1 - 8.8e-07 29.0 9.2 1.7e-06 28.0 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PRP85495.1 - 1.7e-06 27.8 10.2 3.3e-06 26.8 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP85495.1 - 3.7e-06 26.7 8.4 7.1e-06 25.8 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP85495.1 - 5e-06 26.4 8.6 1.2e-05 25.2 8.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP85495.1 - 5.8e-06 26.1 9.0 1e-05 25.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP85495.1 - 7.6e-05 23.0 9.0 0.00015 22.0 9.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PRP85495.1 - 9.6e-05 22.3 9.6 0.0003 20.7 9.6 1.8 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PRP85495.1 - 0.012 15.5 12.9 0.058 13.3 12.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Thump_like PF18096.1 PRP85495.1 - 0.043 13.8 0.2 0.86 9.6 0.0 2.4 2 0 0 2 2 2 0 THUMP domain-like MRNIP PF15749.5 PRP85495.1 - 0.089 13.5 0.9 0.26 12.0 0.9 1.8 1 0 0 1 1 1 0 MRN-interacting protein zf-RING_6 PF14835.6 PRP85495.1 - 0.11 12.4 4.6 0.26 11.2 4.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rubredoxin PF00301.20 PRP85495.1 - 4 7.6 8.1 8.2 6.6 0.5 2.5 2 0 0 2 2 2 0 Rubredoxin zf-MIZ PF02891.20 PRP85495.1 - 7.2 6.4 14.4 31 4.4 14.1 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.6 PRP85495.1 - 8.7 6.2 12.5 40 4.1 12.3 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DSPc PF00782.20 PRP85496.1 - 9.4e-28 96.7 0.0 1.7e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP85496.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-AN1 PF01428.16 PRP85497.1 - 1.4e-10 41.1 14.9 1.8e-10 40.8 11.6 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger CoiA PF06054.11 PRP85497.1 - 0.0027 16.9 0.0 0.0035 16.6 0.0 1.1 1 0 0 1 1 1 1 Competence protein CoiA-like family MqsA_antitoxin PF15731.5 PRP85497.1 - 0.032 14.3 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Transp_Tc5_C PF04236.15 PRP85497.1 - 0.049 14.0 4.4 0.1 13.0 4.4 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain zf_C2HC_14 PF18574.1 PRP85497.1 - 0.24 11.2 4.0 0.14 11.9 1.2 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain zf-DNA_Pol PF08996.10 PRP85497.1 - 2.9 7.6 7.8 20 4.9 5.7 2.1 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger HypA PF01155.19 PRP85497.1 - 3 7.9 6.9 2e+02 2.0 6.9 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 PRP85497.1 - 3.6 7.9 12.5 36 4.7 12.4 2.3 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DEP PF00610.21 PRP85498.1 - 8.1e-07 29.0 0.0 1.8e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF547 PF04784.14 PRP85498.1 - 5.2e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 HNH_2 PF13391.6 PRP85498.1 - 0.022 14.9 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease Integrin_beta PF00362.18 PRP85499.1 - 0.12 12.0 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 Integrin beta chain VWA domain Glyco_hydro_88 PF07470.13 PRP85500.1 - 2.4e-10 40.0 2.9 1.6e-05 24.2 0.4 2.3 2 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.20 PRP85500.1 - 0.0027 16.7 0.6 0.012 14.5 0.0 2.1 3 0 0 3 3 3 1 Glycosyl hydrolase family 47 LANC_like PF05147.13 PRP85500.1 - 0.041 12.5 0.0 2.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein Glyco_hydro_127 PF07944.12 PRP85500.1 - 0.088 11.3 0.0 6.3 5.2 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 PARP PF00644.20 PRP85501.1 - 1.9e-07 30.8 0.0 7.2e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 PRP85501.1 - 9.3e-05 22.5 0.1 0.00039 20.5 0.0 2.0 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain MitMem_reg PF13012.6 PRP85501.1 - 0.15 12.5 0.3 0.32 11.4 0.3 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Pkinase PF00069.25 PRP85502.1 - 3.4e-75 252.8 0.0 5.8e-75 252.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85502.1 - 9e-42 143.1 0.0 1.4e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 PRP85502.1 - 4.6e-15 55.1 0.7 9e-15 54.2 0.7 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Methyltransf_25 PF13649.6 PRP85502.1 - 2.3e-12 47.4 0.0 1.3e-11 45.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP85502.1 - 3.8e-11 43.5 0.0 1.3e-10 41.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP85502.1 - 1.4e-08 34.7 0.0 4.5e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Kinase-like PF14531.6 PRP85502.1 - 8.8e-07 28.5 0.0 7.6e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Methyltransf_PK PF05891.12 PRP85502.1 - 9.6e-06 25.3 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 PRP85502.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 PRP85502.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) APH PF01636.23 PRP85502.1 - 0.029 14.3 0.1 0.076 12.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PRP85502.1 - 0.041 13.5 0.1 0.091 12.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 PRP85502.1 - 0.045 12.7 0.1 0.084 11.8 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 PRP85502.1 - 0.083 11.7 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC TehB PF03848.14 PRP85502.1 - 0.084 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB FBP_C PF16571.5 PRP85503.1 - 0.068 12.7 0.0 0.096 12.2 0.0 1.2 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Ank_4 PF13637.6 PRP85504.1 - 0.014 15.9 0.0 15 6.3 0.0 3.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85504.1 - 0.17 12.5 0.2 24 5.9 0.0 4.2 6 0 0 6 6 6 0 Ankyrin repeat DUF2256 PF10013.9 PRP85505.1 - 2e-16 59.8 9.3 4.1e-16 58.8 9.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) DUF3253 PF11625.8 PRP85505.1 - 8.8e-08 32.3 0.4 1.7e-06 28.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3253) Ecl1 PF12855.7 PRP85505.1 - 0.041 15.1 0.1 0.064 14.4 0.1 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 PRP85505.1 - 2.5 8.3 8.5 0.2 11.8 1.2 2.2 2 0 0 2 2 2 0 MYND finger Abhydrolase_3 PF07859.13 PRP85506.1 - 1.8e-10 41.0 0.6 1.9e-05 24.6 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PRP85506.1 - 7.9e-09 35.3 0.0 3.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 PRP85506.1 - 0.00064 18.7 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.9 PRP85506.1 - 0.0042 16.6 1.2 1.2 8.5 0.5 3.0 3 0 0 3 3 3 2 Esterase PHB depolymerase Chlorophyllase PF07224.11 PRP85506.1 - 0.014 14.4 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase DLH PF01738.18 PRP85506.1 - 0.021 14.4 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family COesterase PF00135.28 PRP85506.1 - 0.025 13.5 0.0 1 8.1 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family AXE1 PF05448.12 PRP85506.1 - 0.16 10.6 0.0 3 6.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Bact_lectin PF18483.1 PRP85507.1 - 6.1e-27 94.9 0.0 1e-26 94.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 PRP85507.1 - 1e-16 61.2 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Legume lectin domain Transglut_core PF01841.19 PRP85507.1 - 4.5e-15 56.1 0.5 1e-14 54.9 0.5 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 PRP85507.1 - 1.1e-12 47.9 0.1 2.4e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Lectin_leg-like PF03388.13 PRP85507.1 - 3.1e-09 36.5 0.0 7.4e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Legume-like lectin family PAW PF04721.17 PRP85507.1 - 0.00014 21.7 0.2 0.00023 21.0 0.2 1.4 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW UPF0020 PF01170.18 PRP85508.1 - 9e-29 100.6 0.4 4.6e-28 98.3 0.4 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 PRP85508.1 - 1.2e-05 25.0 0.0 1.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 RRNA methyltransferase AviRa Methyltransf_11 PF08241.12 PRP85508.1 - 2.9e-05 24.6 0.0 8.6e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP85508.1 - 9.6e-05 23.0 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP85508.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PRP85508.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CDC45 PF02724.14 PRP85508.1 - 0.078 11.3 5.8 0.11 10.8 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PCSK9_C1 PF18459.1 PRP85508.1 - 1 9.5 3.1 0.84 9.8 0.1 2.3 3 0 0 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain FemAB PF02388.16 PRP85508.1 - 1.3 7.8 7.1 2 7.2 7.1 1.2 1 0 0 1 1 1 0 FemAB family Sec62 PF03839.16 PRP85508.1 - 2.1 7.8 8.7 4.4 6.8 8.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 PRP85508.1 - 3.5 7.3 5.0 7.6 6.2 5.0 1.5 1 0 0 1 1 1 0 Connexin HAUS5 PF14817.6 PRP85509.1 - 6.5e-09 35.1 5.4 1e-06 27.9 3.7 2.1 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 5 WD40 PF00400.32 PRP85510.1 - 1.5e-06 28.8 1.2 0.00091 20.0 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP85510.1 - 0.00021 21.5 0.0 0.23 11.8 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP85510.1 - 0.029 13.3 3.3 3.8 6.4 0.1 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PRP85510.1 - 0.15 10.6 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Phage_30_8 PF06019.11 PRP85511.1 - 0.13 12.1 0.3 6.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Phage GP30.8 protein AT_hook PF02178.19 PRP85511.1 - 0.52 10.4 4.4 1.2 9.2 4.4 1.7 1 0 0 1 1 1 0 AT hook motif UEV PF05743.13 PRP85512.1 - 1.9e-31 108.4 0.2 3.1e-31 107.7 0.2 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 PRP85512.1 - 2.8e-18 65.6 0.2 5.8e-18 64.6 0.2 1.5 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 PRP85512.1 - 0.0058 16.3 0.7 0.013 15.1 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme XhlA PF10779.9 PRP85512.1 - 0.16 12.2 0.5 0.35 11.1 0.5 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Lebercilin PF15619.6 PRP85512.1 - 0.82 9.3 4.4 0.21 11.2 1.2 1.5 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SRTM1 PF15872.5 PRP85513.1 - 0.1 12.8 2.1 0.14 12.4 0.0 2.3 2 2 1 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 Aldo_ket_red PF00248.21 PRP85514.1 - 9.9e-76 254.7 0.0 1.1e-75 254.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BCL9 PF11502.8 PRP85515.1 - 0.0097 15.7 0.2 0.026 14.3 0.2 1.7 1 0 0 1 1 1 1 B-cell lymphoma 9 protein DHHC PF01529.20 PRP85516.1 - 6.8e-25 87.7 11.4 6.8e-25 87.7 11.4 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Abhydrolase_2 PF02230.16 PRP85516.1 - 0.00049 20.0 0.0 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PRP85516.1 - 0.00074 19.0 0.1 0.0044 16.5 0.0 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 PRP85516.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Lipase_3 PF01764.25 PRP85516.1 - 0.045 13.6 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Lipase (class 3) DUF915 PF06028.11 PRP85516.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 PRP85516.1 - 0.079 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 PRP85516.1 - 0.086 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Hydrolase_4 PF12146.8 PRP85516.1 - 0.12 11.6 0.0 0.47 9.7 0.0 1.8 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Defensin_2 PF01097.18 PRP85516.1 - 0.74 9.8 13.5 0.93 9.5 1.4 3.0 2 1 0 2 2 2 0 Arthropod defensin F-box-like PF12937.7 PRP85517.1 - 7.1e-08 32.2 0.1 2.5e-07 30.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP85517.1 - 0.00018 21.3 0.8 0.00018 21.3 0.8 3.0 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 PRP85517.1 - 0.0051 16.7 0.4 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 F-box LRR_4 PF12799.7 PRP85517.1 - 0.52 10.8 4.0 17 6.0 0.0 4.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) GST_N PF02798.20 PRP85518.1 - 6.7e-18 64.8 0.0 1.6e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP85518.1 - 2e-13 50.5 0.0 3.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP85518.1 - 6.3e-11 42.3 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP85518.1 - 7.2e-11 42.2 0.3 2e-10 40.7 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PRP85518.1 - 2.1e-09 37.5 0.1 6.4e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP85518.1 - 1.1e-07 31.8 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 PRP85518.1 - 0.029 14.2 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribonucleas_3_3 PF14622.6 PRP85519.1 - 4e-39 133.7 0.0 2.9e-18 66.3 0.0 3.3 3 0 0 3 3 3 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PRP85519.1 - 9.5e-38 129.0 0.0 1.6e-17 64.0 0.0 3.4 2 1 0 2 2 2 2 Ribonuclease III domain Arg_decarb_HB PF17810.1 PRP85519.1 - 0.065 13.5 0.1 0.28 11.5 0.1 2.2 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain DUF480 PF04337.12 PRP85519.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF480 Cupin_4 PF08007.12 PRP85520.1 - 3.1e-11 43.3 0.2 2e-10 40.7 0.1 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 PRP85520.1 - 1e-09 38.5 0.0 2.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 PRP85520.1 - 0.0015 18.2 0.0 0.0045 16.7 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Rep-A_N PF04057.12 PRP85520.1 - 0.076 13.0 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain CH PF00307.31 PRP85521.1 - 1.2e-33 115.5 0.1 1.6e-17 63.7 1.1 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain Filamin PF00630.19 PRP85521.1 - 6.2e-20 71.9 7.4 9.4e-07 29.6 0.1 5.7 4 1 1 5 5 5 4 Filamin/ABP280 repeat AMPK1_CBM PF16561.5 PRP85521.1 - 8.8e-10 38.7 0.3 4.1e-09 36.5 0.1 2.3 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase FixH PF05751.11 PRP85521.1 - 1.5e-05 25.0 4.2 0.78 9.7 0.1 5.7 3 1 2 5 5 5 1 FixH TPR_16 PF13432.6 PRP85521.1 - 8.3e-05 23.2 0.0 0.00082 20.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Trypan_PARP PF05887.11 PRP85521.1 - 9.5e-05 22.4 20.8 9.5e-05 22.4 20.8 2.6 2 0 0 2 2 1 1 Procyclic acidic repetitive protein (PARP) MG2 PF01835.19 PRP85521.1 - 0.00024 21.5 1.5 4.3 7.9 0.0 5.2 4 1 0 4 4 4 1 MG2 domain TPR_2 PF07719.17 PRP85521.1 - 0.00043 20.2 0.2 2.8 8.3 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP85521.1 - 0.0048 16.7 0.0 9.6 6.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP85521.1 - 0.005 17.6 0.1 0.32 11.9 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat CBM_48 PF02922.18 PRP85521.1 - 0.0069 16.7 0.2 0.13 12.6 0.1 3.0 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) TcfC PF16967.5 PRP85521.1 - 0.049 13.1 0.0 16 5.1 0.0 2.7 2 0 0 2 2 2 0 E-set like domain TPR_9 PF13371.6 PRP85521.1 - 0.051 13.7 0.3 1.2 9.3 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat CAMSAP_CH PF11971.8 PRP85521.1 - 0.17 11.8 0.0 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 CAMSAP CH domain NARP1 PF12569.8 PRP85521.1 - 0.17 10.8 4.8 2.3 7.0 6.2 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 ATP-synt_E PF05680.12 PRP85521.1 - 5.4 7.4 10.5 21 5.5 10.5 2.0 1 0 0 1 1 1 0 ATP synthase E chain BORG_CEP PF14957.6 PRP85523.1 - 0.43 11.7 5.3 0.22 12.7 0.9 2.2 2 0 0 2 2 2 0 Cdc42 effector DUF3430 PF11912.8 PRP85524.1 - 0.00017 21.7 13.5 0.00024 21.2 13.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) PA14 PF07691.12 PRP85525.1 - 4.2e-10 39.6 0.0 1.5e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 PRP85525.1 - 1.9e-06 27.7 5.1 1.9e-06 27.7 5.1 9.1 7 1 1 8 8 8 3 Dictyostelium (slime mold) repeat Translin PF01997.16 PRP85526.1 - 1.2e-56 192.0 0.6 1.7e-56 191.4 0.6 1.2 1 0 0 1 1 1 1 Translin family Pkinase PF00069.25 PRP85528.1 - 2.8e-64 217.0 0.1 4.1e-64 216.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85528.1 - 2.3e-42 145.1 0.0 3.6e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 PRP85528.1 - 1.8e-17 63.5 0.0 4.7e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain WW PF00397.26 PRP85528.1 - 5.8e-09 35.9 6.8 5.8e-09 35.9 6.8 2.3 2 0 0 2 2 2 1 WW domain Kinase-like PF14531.6 PRP85528.1 - 1.7e-07 30.8 1.2 2.6e-06 27.0 0.1 2.4 2 1 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 PRP85528.1 - 0.0018 17.2 0.0 0.0018 17.2 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase Glyco_hydro_cc PF11790.8 PRP85530.1 - 7.5e-38 130.4 0.0 1.4e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_61 PF03443.14 PRP85530.1 - 7e-15 55.5 0.0 1.3e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 PRP85530.1 - 3.3e-07 31.2 0.4 3.3e-07 31.2 0.4 2.7 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Trypan_PARP PF05887.11 PRP85530.1 - 0.078 13.0 1.7 0.14 12.1 1.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Transket_pyr PF02779.24 PRP85531.1 - 3.9e-63 212.3 0.0 1.1e-62 210.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 PRP85531.1 - 3.5e-57 193.6 0.0 1.3e-56 191.8 0.0 1.8 1 1 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 PRP85531.1 - 1.1e-47 161.5 0.1 1.1e-47 161.5 0.1 1.7 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 PRP85531.1 - 1.1e-17 63.3 1.1 1.1e-17 63.3 1.1 2.2 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Ras PF00071.22 PRP85531.1 - 3.9e-09 36.3 0.0 8.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Ras family Ras PF00071.22 PRP85532.1 - 3.9e-47 159.9 0.2 6.1e-47 159.2 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP85532.1 - 2.3e-21 76.2 0.3 4.8e-21 75.2 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP85532.1 - 2.1e-07 30.6 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP85532.1 - 0.0042 16.7 0.0 0.0082 15.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RCC1 PF00415.18 PRP85533.1 - 2.1e-45 153.1 14.3 1e-11 45.2 0.1 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP85533.1 - 1.8e-21 75.4 28.3 2.8e-05 23.8 1.3 7.6 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat LAG1-DNAbind PF09271.11 PRP85533.1 - 0.097 13.3 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 LAG1, DNA binding EF-hand_7 PF13499.6 PRP85535.1 - 8.5e-20 71.0 0.9 3.9e-13 49.7 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP85535.1 - 9.3e-19 65.5 6.5 1.9e-07 30.1 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 PRP85535.1 - 2.5e-17 61.2 0.1 5.1e-06 26.0 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PRP85535.1 - 5.7e-16 58.1 5.7 9.4e-12 44.6 0.2 4.0 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP85535.1 - 3.9e-11 41.9 4.1 3.5e-05 23.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 PRP85535.1 - 9.6e-09 35.5 0.1 0.00021 21.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PRP85535.1 - 2.9e-07 30.4 0.7 8.1e-05 22.5 0.3 2.3 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 PRP85535.1 - 0.0014 17.3 0.0 0.0027 16.3 0.0 1.4 1 1 1 2 2 2 1 Family of unknown function (DUF5580) TerB PF05099.13 PRP85535.1 - 0.067 13.1 0.0 2.1 8.3 0.1 2.7 2 1 0 2 2 2 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.9 PRP85535.1 - 0.07 13.5 0.1 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MgtE_N PF03448.17 PRP85535.1 - 0.099 13.3 0.3 6.4 7.4 0.0 2.2 1 1 0 2 2 2 0 MgtE intracellular N domain UQ_con PF00179.26 PRP85536.1 - 1.8e-50 170.3 0.0 2e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PRP85536.1 - 0.092 12.4 0.0 0.17 11.6 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B ketoacyl-synt PF00109.26 PRP85537.1 - 1.1e-51 175.9 0.0 1.7e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PRP85537.1 - 2e-38 131.0 0.3 3.1e-38 130.4 0.3 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 PRP85537.1 - 0.0043 16.4 0.3 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain UPF0564 PF10595.9 PRP85538.1 - 1.7e-06 27.3 58.5 9.1e-05 21.7 1.7 4.5 3 2 1 4 4 4 3 Uncharacterised protein family UPF0564 YjbH PF06082.11 PRP85538.1 - 4.2 6.0 10.2 2 7.1 4.9 2.2 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH DUF722 PF05263.11 PRP85539.1 - 0.079 13.2 0.1 0.079 13.2 0.1 4.6 1 1 3 5 5 5 0 Protein of unknown function (DUF722) DUF2205 PF10224.9 PRP85539.1 - 0.14 12.2 0.2 0.14 12.2 0.2 3.8 2 2 1 3 3 3 0 Short coiled-coil protein Ribosomal_60s PF00428.19 PRP85539.1 - 0.46 11.1 3.0 1.6 9.4 0.6 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein ATG16 PF08614.11 PRP85539.1 - 5.7 7.1 46.1 1.5 9.0 21.0 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Ribosomal_S13 PF00416.22 PRP85540.1 - 3.5e-14 53.3 0.1 2e-12 47.6 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 IMS_HHH PF11798.8 PRP85540.1 - 0.016 15.5 0.0 0.89 10.0 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif FAM178 PF14816.6 PRP85541.1 - 1.2e-07 31.1 0.8 0.00041 19.5 0.2 2.6 1 1 1 2 2 2 2 Family of unknown function, FAM178 RNA_pol_Rpo13 PF12136.8 PRP85541.1 - 0.18 11.8 2.7 0.4 10.6 2.7 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain DHR-2 PF06920.13 PRP85542.1 - 3.1e-68 230.7 0.0 1.3e-67 228.6 0.0 2.1 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 PRP85542.1 - 2.1e-25 89.7 0.1 2.5e-24 86.2 0.0 2.6 2 1 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_9 PF14604.6 PRP85542.1 - 0.00011 22.0 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP85542.1 - 0.001 18.7 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP85542.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain C2 PF00168.30 PRP85542.1 - 0.011 16.0 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 C2 domain hSH3 PF14603.6 PRP85542.1 - 0.11 13.0 0.0 0.38 11.2 0.0 1.9 1 0 0 1 1 1 0 Helically-extended SH3 domain Zn_clus PF00172.18 PRP85543.1 - 6.3e-06 26.2 12.0 1.4e-05 25.1 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IFT57 PF10498.9 PRP85543.1 - 0.012 14.6 0.5 0.018 14.1 0.5 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 KilA-N PF04383.13 PRP85543.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 KilA-N domain UvrD-helicase PF00580.21 PRP85545.1 - 4.3e-60 203.9 0.1 2.9e-59 201.1 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PRP85545.1 - 4.3e-52 177.6 0.0 2.6e-25 89.6 0.0 3.4 3 1 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PRP85545.1 - 8.3e-33 113.8 0.0 3.7e-32 111.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 PRP85545.1 - 2.9e-11 43.0 0.0 3.3e-10 39.6 0.0 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 PRP85545.1 - 2.8e-10 40.2 0.0 3.8e-08 33.3 0.0 2.6 1 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PRP85545.1 - 1.9e-08 34.4 0.0 0.018 14.8 0.0 3.6 3 1 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 PRP85545.1 - 9.7e-07 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 PRP85545.1 - 1.1e-05 25.2 1.2 0.43 10.2 0.0 4.3 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 PRP85545.1 - 0.0057 16.9 0.1 0.22 11.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.9 PRP85545.1 - 0.0059 15.9 0.0 0.025 13.9 0.0 2.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 PRP85545.1 - 0.097 12.7 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UBX PF00789.20 PRP85546.1 - 0.0047 17.1 0.5 0.011 16.0 0.0 1.9 2 1 0 2 2 2 1 UBX domain WBS_methylT PF12589.8 PRP85546.1 - 9.3 7.1 9.5 5.5 7.8 1.2 2.3 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome DER1 PF04511.15 PRP85547.1 - 8.8e-45 153.0 12.9 1e-44 152.8 12.9 1.0 1 0 0 1 1 1 1 Der1-like family FAM177 PF14774.6 PRP85547.1 - 0.017 15.5 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 FAM177 family TPR_1 PF00515.28 PRP85549.1 - 4.4e-98 317.5 16.9 6.2e-08 32.1 0.0 18.4 18 1 0 19 19 18 16 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85549.1 - 2e-76 246.1 13.9 4.7e-06 26.3 0.1 17.6 16 1 1 17 17 17 13 Tetratricopeptide repeat TPR_11 PF13414.6 PRP85549.1 - 2.1e-61 203.4 25.8 9.1e-06 25.3 0.0 16.8 9 5 10 19 19 19 13 TPR repeat TPR_8 PF13181.6 PRP85549.1 - 1.2e-54 178.0 25.9 1.1e-05 25.2 0.1 17.8 17 1 1 18 18 18 9 Tetratricopeptide repeat TPR_17 PF13431.6 PRP85549.1 - 2.1e-54 178.1 16.5 0.0037 17.6 0.0 17.1 17 0 0 17 17 17 13 Tetratricopeptide repeat TPR_9 PF13371.6 PRP85549.1 - 1.7e-51 172.3 0.1 4e-06 26.9 0.4 12.2 5 4 8 13 13 13 12 Tetratricopeptide repeat TPR_16 PF13432.6 PRP85549.1 - 8.1e-47 157.6 0.0 1.6e-06 28.6 0.2 10.3 7 2 4 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.6 PRP85549.1 - 9.1e-36 122.0 18.3 3.9e-05 23.9 0.1 11.7 4 3 8 12 12 12 9 Tetratricopeptide repeat TPR_19 PF14559.6 PRP85549.1 - 9e-24 83.8 18.7 4.5e-05 23.9 0.1 9.5 7 2 4 11 11 11 7 Tetratricopeptide repeat TPR_6 PF13174.6 PRP85549.1 - 7.5e-21 73.3 13.8 0.042 14.5 0.0 14.6 17 0 0 17 17 15 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP85549.1 - 1.7e-20 71.9 9.0 0.049 14.5 0.4 12.1 5 4 6 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 PRP85549.1 - 1.5e-17 62.2 15.1 0.81 9.9 0.0 13.8 14 2 2 16 16 14 2 Tetratricopeptide repeat TPR_10 PF13374.6 PRP85549.1 - 2e-17 62.5 11.1 0.055 13.4 0.0 11.5 11 0 0 11 11 11 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 PRP85549.1 - 1e-13 50.5 0.2 0.079 12.4 0.0 10.3 11 0 0 11 11 11 2 SHNi-TPR ANAPC3 PF12895.7 PRP85549.1 - 3.2e-12 46.5 14.2 4.5e-07 30.0 0.6 6.7 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 PRP85549.1 - 1.2e-06 28.2 0.3 0.032 13.6 0.2 4.9 5 1 1 6 6 6 1 MalT-like TPR region DUF3856 PF12968.7 PRP85549.1 - 3.5e-05 23.9 7.4 16 5.6 0.1 7.7 4 2 2 7 7 7 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 PRP85549.1 - 5.5e-05 23.6 2.5 3.9 7.9 0.0 5.1 3 1 2 5 5 4 1 Bacterial transcriptional activator domain DUF3808 PF10300.9 PRP85549.1 - 0.0003 19.6 3.3 0.3 9.8 0.0 4.0 2 1 2 4 4 4 2 Protein of unknown function (DUF3808) TPR_20 PF14561.6 PRP85549.1 - 0.0028 17.9 8.7 2.2 8.7 0.1 5.8 4 2 0 5 5 5 1 Tetratricopeptide repeat DUF5113 PF17140.4 PRP85549.1 - 0.0029 17.4 13.9 0.53 10.1 0.1 6.8 4 2 3 8 8 8 1 Domain of unknown function (DUF5113) DUF627 PF04781.12 PRP85549.1 - 0.0092 16.0 0.2 0.42 10.7 0.0 3.7 4 1 1 5 5 4 1 Protein of unknown function (DUF627) ANAPC5 PF12862.7 PRP85549.1 - 0.013 15.6 6.0 21 5.3 0.0 6.2 6 3 3 9 9 7 0 Anaphase-promoting complex subunit 5 SRP_TPR_like PF17004.5 PRP85549.1 - 0.11 12.5 6.6 0.55 10.3 0.1 3.9 3 1 1 4 4 4 0 Putative TPR-like repeat 4HB_MCP_1 PF12729.7 PRP85549.1 - 0.23 11.0 3.0 0.28 10.7 0.0 2.7 3 0 0 3 3 2 0 Four helix bundle sensory module for signal transduction Tox-REase-3 PF15647.6 PRP85549.1 - 0.25 11.6 2.0 9.3 6.6 0.0 3.4 3 0 0 3 3 3 0 Restriction endonuclease fold toxin 3 HemY_N PF07219.13 PRP85549.1 - 1 9.6 3.8 11 6.2 0.0 4.1 5 2 0 5 5 4 0 HemY protein N-terminus Fis1_TPR_C PF14853.6 PRP85549.1 - 1.2 9.3 14.2 1.9 8.7 0.0 6.2 9 0 0 9 9 5 0 Fis1 C-terminal tetratricopeptide repeat Zn_clus PF00172.18 PRP85550.1 - 4.8e-06 26.6 13.1 4.8e-06 26.6 13.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain S1 PF00575.23 PRP85551.1 - 4.8e-10 39.6 0.3 4.8e-10 39.6 0.3 1.8 2 0 0 2 2 2 1 S1 RNA binding domain Coilin_N PF15862.5 PRP85551.1 - 2.5e-07 30.6 0.0 1.2e-06 28.4 0.0 2.0 2 1 0 2 2 2 1 Coilin N-terminus zf-CCHC_5 PF14787.6 PRP85551.1 - 6e-05 22.7 0.3 0.00015 21.4 0.3 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger CpXC PF14353.6 PRP85551.1 - 0.012 15.7 2.2 0.013 15.5 0.6 1.8 2 0 0 2 2 2 0 CpXC protein zf-CCHC PF00098.23 PRP85551.1 - 0.019 15.1 2.9 0.039 14.0 2.9 1.5 1 0 0 1 1 1 0 Zinc knuckle Mu-like_Com PF10122.9 PRP85551.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com Fer4_13 PF13370.6 PRP85551.1 - 0.1 13.1 0.4 0.29 11.7 0.3 1.8 1 1 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I Presenilin PF01080.17 PRP85551.1 - 1.5 7.5 5.5 0.22 10.3 1.7 1.6 2 0 0 2 2 2 0 Presenilin EOS1 PF12326.8 PRP85551.1 - 3 7.8 4.6 3.9 7.4 4.6 1.4 1 1 0 1 1 1 0 N-glycosylation protein RhoGAP PF00620.27 PRP85552.1 - 7.3e-42 142.8 0.2 4.3e-41 140.3 0.1 2.4 2 0 0 2 2 2 1 RhoGAP domain PRP4 PF08799.11 PRP85552.1 - 0.063 12.8 0.2 0.31 10.6 0.2 2.2 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Gluconate_2-dh3 PF13618.6 PRP85552.1 - 0.22 11.7 1.3 0.52 10.5 1.3 1.6 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 HORMA PF02301.18 PRP85553.1 - 5e-22 78.5 0.5 1.1e-21 77.4 0.5 1.5 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 PRP85553.1 - 0.04 13.7 0.3 0.17 11.7 0.1 1.9 1 1 1 2 2 2 0 Bacterial HORMA domain 2 DUF2791 PF10923.8 PRP85553.1 - 0.051 12.4 0.2 0.071 11.9 0.2 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ALAD PF00490.21 PRP85553.1 - 0.13 11.4 0.1 0.19 10.9 0.1 1.1 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase CTP_transf_like PF01467.26 PRP85554.1 - 3.4e-14 53.3 0.0 5.9e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like SpoU_methylase PF00588.19 PRP85555.1 - 5.4e-15 55.8 0.0 3.6e-14 53.2 0.0 1.9 1 1 0 1 1 1 1 SpoU rRNA Methylase family Pkinase PF00069.25 PRP85556.1 - 4.5e-63 213.1 0.0 7.5e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85556.1 - 1.2e-41 142.7 0.0 2e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP85556.1 - 2.6e-06 27.0 0.0 6.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP85556.1 - 0.00046 19.3 0.9 0.00094 18.2 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP85556.1 - 0.0024 16.7 0.0 0.0024 16.7 0.0 2.0 2 1 1 3 3 3 1 Fungal protein kinase UPF0242 PF06785.11 PRP85556.1 - 0.0073 16.4 11.1 0.015 15.4 11.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Kdo PF06293.14 PRP85556.1 - 0.019 14.3 2.2 0.053 12.9 0.0 2.5 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP85556.1 - 0.027 14.4 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PRP85556.1 - 0.042 12.9 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Herpes_UL6 PF01763.16 PRP85556.1 - 0.07 11.6 5.3 0.11 11.1 5.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like TolA_bind_tri PF16331.5 PRP85556.1 - 2.4 8.3 11.6 6.9 6.8 11.6 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation APG6_N PF17675.1 PRP85556.1 - 3.2 8.3 9.5 7.4 7.1 9.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Peptidase_C97 PF05903.14 PRP85557.1 - 1.4e-25 89.9 0.0 1.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain Vps39_2 PF10367.9 PRP85557.1 - 0.002 18.6 0.0 0.0042 17.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Ank_2 PF12796.7 PRP85558.1 - 4.2e-16 59.3 0.0 0.00048 20.7 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) RTTN_N PF14726.6 PRP85558.1 - 2.5e-14 53.8 3.6 1.1e-12 48.6 0.3 4.1 2 1 0 2 2 2 1 Rotatin, an armadillo repeat protein, centriole functioning Ank_4 PF13637.6 PRP85558.1 - 2.3e-12 47.2 2.0 0.0092 16.6 0.0 7.0 6 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85558.1 - 7.2e-11 42.1 6.5 1 9.8 0.1 8.8 4 1 5 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85558.1 - 1.7e-08 34.0 8.6 4.8 8.1 0.0 8.9 8 0 0 8 8 8 1 Ankyrin repeat Las1 PF04031.13 PRP85558.1 - 0.071 13.2 0.1 1.6 8.8 0.1 3.3 2 0 0 2 2 2 0 Las1-like Ank PF00023.30 PRP85558.1 - 0.12 12.8 10.7 82 3.9 0.1 6.8 8 0 0 8 8 8 0 Ankyrin repeat Peptidase_M42 PF05343.14 PRP85558.1 - 0.18 10.8 0.1 0.36 9.8 0.1 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Annexin PF00191.20 PRP85559.1 - 1.7e-87 287.5 8.6 2.2e-23 82.1 0.1 4.1 4 0 0 4 4 4 4 Annexin DUF123 PF01986.16 PRP85559.1 - 0.011 16.2 0.4 0.33 11.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF123 WD40 PF00400.32 PRP85560.1 - 2.1e-09 37.8 3.8 0.0046 17.8 0.4 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat BRE PF06113.12 PRP85560.1 - 7.1e-08 31.6 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Nup160 PF11715.8 PRP85560.1 - 2.1e-05 23.4 0.2 0.17 10.5 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PRP85560.1 - 4.6e-05 23.6 0.2 0.15 12.4 0.4 3.5 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP85560.1 - 0.0022 17.0 0.1 0.018 14.0 0.0 2.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Tmemb_170 PF10190.9 PRP85561.1 - 5.9e-14 52.3 13.6 1.4e-13 51.1 13.6 1.5 1 1 0 1 1 1 1 Putative transmembrane protein 170 DUF2721 PF11026.8 PRP85561.1 - 6.7 6.6 8.7 2 8.3 5.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2721) Homeodomain PF00046.29 PRP85562.1 - 3.5e-12 46.0 0.7 2.2e-11 43.4 1.1 2.1 2 0 0 2 2 2 1 Homeodomain PHD PF00628.29 PRP85562.1 - 1.3e-10 41.0 7.7 3.4e-10 39.7 7.7 1.8 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 PRP85562.1 - 0.032 14.5 5.4 0.078 13.2 5.4 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Homeobox_KN PF05920.11 PRP85562.1 - 0.05 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain zf-HC5HC2H_2 PF13832.6 PRP85562.1 - 0.076 13.2 4.1 0.18 12.0 4.1 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain Phage_CI_repr PF07022.13 PRP85562.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain PHD_2 PF13831.6 PRP85562.1 - 0.37 10.4 2.1 0.91 9.1 2.1 1.7 1 0 0 1 1 1 0 PHD-finger CH PF00307.31 PRP85563.1 - 6.8e-19 68.1 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain LIM PF00412.22 PRP85563.1 - 6e-13 48.8 6.9 1.2e-12 47.9 6.9 1.5 1 0 0 1 1 1 1 LIM domain CDC24 PF06395.11 PRP85563.1 - 0.00088 19.5 0.2 0.0018 18.5 0.2 1.4 1 0 0 1 1 1 1 CDC24 Calponin zinc_ribbon_10 PF10058.9 PRP85563.1 - 0.047 13.4 0.7 0.1 12.4 0.7 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein CAMSAP_CH PF11971.8 PRP85563.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain DUF1660 PF07874.11 PRP85563.1 - 0.22 12.0 2.7 0.85 10.2 2.7 2.1 1 0 0 1 1 1 0 Prophage protein (DUF1660) SIR2 PF02146.17 PRP85563.1 - 2.5 8.0 5.9 1.8 8.5 1.1 2.3 1 1 1 2 2 2 0 Sir2 family RNHCP PF12647.7 PRP85563.1 - 3.3 7.8 6.9 4.2 7.4 4.2 2.2 1 1 1 2 2 2 0 RNHCP domain HSP70 PF00012.20 PRP85564.1 - 6.3e-262 870.1 8.1 7.2e-262 869.9 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP85564.1 - 7.5e-15 54.6 0.1 1e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 PRP85564.1 - 0.00089 18.3 0.3 0.031 13.3 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 PRP85564.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 PRP85564.1 - 0.017 14.6 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 PRP85564.1 - 0.058 12.7 1.1 0.18 11.0 0.1 2.4 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase PKK PF12474.8 PRP85564.1 - 5.7 7.1 12.7 0.27 11.3 6.9 1.7 2 0 0 2 2 2 0 Polo kinase kinase TBCA PF02970.16 PRP85564.1 - 8.3 6.8 11.6 3.3 8.1 8.4 2.0 2 0 0 2 2 2 0 Tubulin binding cofactor A PEMT PF04191.13 PRP85565.1 - 4.1e-05 23.9 2.5 9.9e-05 22.7 1.6 2.2 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 PRP85565.1 - 5.5e-05 22.8 0.7 8.5e-05 22.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 PRP85565.1 - 0.0072 16.7 0.2 0.021 15.2 0.2 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family UPF0552 PF10574.9 PRP85566.1 - 7.1e-13 48.4 3.8 2.4e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 Arp2/3-interacting proteins Arpin FHA PF00498.26 PRP85566.1 - 0.1 13.0 0.0 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 FHA domain ZZ PF00569.17 PRP85567.1 - 1.3e-15 56.9 22.7 1.2e-09 37.8 9.5 2.4 2 0 0 2 2 2 2 Zinc finger, ZZ type C1_2 PF03107.16 PRP85567.1 - 0.00019 21.6 25.6 0.002 18.4 8.4 2.7 3 0 0 3 3 3 2 C1 domain DZR PF12773.7 PRP85567.1 - 0.017 15.1 19.4 1.8e+02 2.2 19.4 3.1 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 PRP85567.1 - 0.026 14.4 20.3 0.081 12.8 5.2 3.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CarbpepA_inh PF02977.15 PRP85567.1 - 0.028 14.2 8.4 0.79 9.6 2.4 2.6 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor DUF35_N PF12172.8 PRP85567.1 - 0.035 14.0 10.1 0.34 10.8 0.6 2.9 2 1 1 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-ACC PF17848.1 PRP85567.1 - 2.1 8.5 11.4 16 5.7 0.1 4.3 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain Kdo PF06293.14 PRP85569.1 - 1.6e-07 30.9 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PRP85569.1 - 7.4e-07 28.8 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP85569.1 - 3.4e-05 23.9 0.0 5.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP85569.1 - 4.1e-05 23.2 0.0 7.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.11 PRP85569.1 - 9.3e-05 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.17 PRP85569.1 - 0.01 15.1 0.1 0.018 14.3 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 PRP85569.1 - 0.072 12.7 0.3 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1538 PF07556.11 PRP85570.1 - 0.2 10.9 0.0 0.22 10.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) zf-RVT PF13966.6 PRP85573.1 - 0.0023 18.6 3.4 0.0058 17.3 3.4 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF5077 PF16871.5 PRP85573.1 - 0.094 12.6 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5077) NinD PF17466.2 PRP85573.1 - 0.11 12.5 0.7 0.35 11.0 0.7 1.9 1 0 0 1 1 1 0 Family of unknown function Pkinase PF00069.25 PRP85574.1 - 1.3e-52 178.7 0.0 1.9e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pyr_redox_2 PF07992.14 PRP85574.1 - 2.4e-32 112.3 0.1 5e-26 91.6 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pkinase_Tyr PF07714.17 PRP85574.1 - 4.5e-27 95.0 0.0 7.2e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pyr_redox PF00070.27 PRP85574.1 - 4.6e-16 59.1 0.3 4.6e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP85574.1 - 4.4e-09 36.0 0.3 2.4e-06 27.0 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP85574.1 - 1.4e-06 28.1 1.4 0.0096 15.5 0.1 3.2 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP85574.1 - 4.3e-05 23.7 0.1 0.0046 17.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 PRP85574.1 - 0.00016 21.1 0.9 0.00071 18.9 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain Kinase-like PF14531.6 PRP85574.1 - 0.00035 20.0 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Lycopene_cycl PF05834.12 PRP85574.1 - 0.00051 19.2 0.0 0.3 10.1 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.14 PRP85574.1 - 0.00082 18.3 0.1 0.35 9.7 0.0 3.1 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_7 PF13241.6 PRP85574.1 - 0.0013 19.1 0.1 2.7 8.5 0.1 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding RIO1 PF01163.22 PRP85574.1 - 0.002 17.7 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PRP85574.1 - 0.0026 17.4 0.1 0.24 11.0 0.0 3.0 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PRP85574.1 - 0.004 16.0 0.0 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase K_oxygenase PF13434.6 PRP85574.1 - 0.0043 16.3 0.6 0.19 10.8 0.1 2.9 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 PRP85574.1 - 0.0047 16.2 0.2 0.11 11.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 PRP85574.1 - 0.005 17.1 3.2 0.027 14.7 0.3 2.4 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_2 PF00890.24 PRP85574.1 - 0.016 14.3 1.7 0.42 9.6 0.1 3.0 3 0 0 3 3 3 0 FAD binding domain Semialdhyde_dh PF01118.24 PRP85574.1 - 0.044 14.2 0.3 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain HI0933_like PF03486.14 PRP85574.1 - 0.058 12.1 0.5 0.42 9.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein DNA_processg_A PF02481.15 PRP85574.1 - 0.066 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA recombination-mediator protein A APH PF01636.23 PRP85574.1 - 0.082 12.8 0.0 0.27 11.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family ThiF PF00899.21 PRP85574.1 - 0.082 12.2 0.4 0.96 8.7 0.1 2.1 2 0 0 2 2 2 0 ThiF family DUF1188 PF06690.11 PRP85574.1 - 0.099 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) AlaDh_PNT_C PF01262.21 PRP85574.1 - 0.15 11.3 5.7 0.14 11.5 0.2 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 PRP85574.1 - 0.23 11.7 2.0 5.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Lipase_3 PF01764.25 PRP85576.1 - 4e-27 94.8 0.0 5.9e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PRP85576.1 - 0.045 14.4 0.1 0.054 14.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP85576.1 - 0.096 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP85576.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Nudix_hydro PF18290.1 PRP85577.1 - 7.1e-29 99.6 0.1 1.7e-28 98.4 0.1 1.7 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 PRP85577.1 - 1.9e-18 66.7 0.0 5.2e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain TMEM214 PF10151.9 PRP85578.1 - 4.3e-11 42.0 3.6 4.3e-11 42.0 3.6 3.1 2 1 0 2 2 2 1 TMEM214, C-terminal, caspase 4 activator DUF5339 PF17274.2 PRP85578.1 - 0.83 10.5 8.6 3.5 8.6 0.0 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5339) RGS PF00615.19 PRP85579.1 - 4.4e-23 81.8 3.6 2.9e-22 79.1 0.1 3.2 3 0 0 3 3 3 1 Regulator of G protein signaling domain cNMP_binding PF00027.29 PRP85579.1 - 2.6e-15 56.2 0.0 2e-06 27.8 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Dicty_REP PF05086.12 PRP85579.1 - 0.011 13.8 0.0 0.011 13.8 0.0 2.1 3 0 0 3 3 3 0 Dictyostelium (Slime Mold) REP protein HTH_1 PF00126.27 PRP85579.1 - 0.14 12.1 0.1 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Ras PF00071.22 PRP85580.1 - 7.6e-59 197.9 0.2 9.7e-59 197.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP85580.1 - 3.8e-37 127.2 0.2 5.3e-37 126.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP85580.1 - 7.4e-15 54.8 0.1 9.1e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PRP85580.1 - 1.6e-06 27.7 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PRP85580.1 - 1.3e-05 24.9 0.2 5.5e-05 22.8 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP85580.1 - 0.00015 21.8 0.0 0.00023 21.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP85580.1 - 0.00023 20.6 0.1 0.00029 20.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PRP85580.1 - 0.0074 16.2 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase TetR_C_16 PF17920.1 PRP85580.1 - 0.04 14.1 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_7 PF12775.7 PRP85580.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RhoGAP PF00620.27 PRP85581.1 - 3e-36 124.5 0.2 4.1e-36 124.1 0.2 1.2 1 0 0 1 1 1 1 RhoGAP domain Bac_surface_Ag PF01103.23 PRP85582.1 - 1.6e-22 80.5 0.0 2.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Arrestin_N PF00339.29 PRP85583.1 - 2.2e-16 60.2 6.8 2.6e-06 27.5 0.0 4.8 6 0 0 6 6 6 3 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PRP85583.1 - 4.6e-14 53.0 6.6 0.013 16.0 0.4 4.4 4 0 0 4 4 4 4 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 PRP85583.1 - 3.8e-05 23.0 6.1 0.064 12.4 0.0 3.6 4 0 0 4 4 4 2 Rgp1 Transglut_C PF00927.22 PRP85583.1 - 0.00063 19.9 1.3 1.3 9.2 0.0 3.0 3 0 0 3 3 3 2 Transglutaminase family, C-terminal ig like domain POC3_POC4 PF10448.9 PRP85583.1 - 0.0036 17.3 0.2 2.7 8.0 0.0 2.5 2 0 0 2 2 2 2 20S proteasome chaperone assembly proteins 3 and 4 Arrestin_N PF00339.29 PRP85584.1 - 2.4e-07 30.9 0.4 9.2e-05 22.5 0.0 3.3 2 2 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PRP85584.1 - 5.6e-07 30.1 0.2 0.0048 17.4 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Transglut_C PF00927.22 PRP85584.1 - 0.058 13.5 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain DUF43 PF01861.16 PRP85584.1 - 0.071 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain DUF2405 PF10293.9 PRP85585.1 - 0.085 12.8 0.0 0.099 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2405) Transglut_N PF00868.20 PRP85585.1 - 0.096 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Transglutaminase family Ras PF00071.22 PRP85587.1 - 4.7e-13 49.1 0.0 3e-07 30.2 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 PRP85587.1 - 5.9e-05 23.3 0.0 0.006 16.8 0.0 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 PRP85587.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 PRP85587.1 - 0.068 13.3 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 PRP85587.1 - 0.07 13.6 0.0 0.095 13.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 PRP85587.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin TniB PF05621.11 PRP85587.1 - 0.2 11.0 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Glyco_hydro_16 PF00722.21 PRP85589.1 - 6.4e-08 32.3 3.4 5.1e-05 22.8 3.4 3.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 UBA PF00627.31 PRP85591.1 - 1.8e-16 59.6 5.9 3.7e-08 33.1 0.2 3.1 3 0 0 3 3 3 2 UBA/TS-N domain STI1 PF17830.1 PRP85591.1 - 0.00019 21.3 0.0 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 STI1 domain FeoA PF04023.14 PRP85591.1 - 0.0057 16.9 0.3 0.12 12.6 0.0 2.7 2 1 0 2 2 2 1 FeoA domain Caprin-1_dimer PF18293.1 PRP85591.1 - 0.17 12.3 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 Caprin-1 dimerization domain ATP-synt_ab PF00006.25 PRP85592.1 - 2.1e-65 220.3 0.0 2.9e-65 219.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PRP85592.1 - 9.9e-13 48.4 0.9 1.9e-12 47.5 0.9 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3762 PF12591.8 PRP85592.1 - 0.16 12.2 0.0 0.5 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Cbl_N PF02262.16 PRP85593.1 - 0.13 12.2 0.7 3.2 7.8 1.1 2.5 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 EF-hand_11 PF08976.11 PRP85593.1 - 0.17 12.8 0.6 0.46 11.4 0.1 2.0 2 1 0 2 2 2 0 EF-hand domain IZUMO PF15005.6 PRP85593.1 - 1.6 9.2 5.1 0.73 10.3 0.7 2.5 2 1 1 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated bZIP_1 PF00170.21 PRP85595.1 - 3.1 8.0 11.5 5.2 7.2 0.2 3.4 1 1 2 3 3 3 0 bZIP transcription factor GAS PF13851.6 PRP85595.1 - 5.6 6.3 26.1 5.4 6.3 24.2 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Peroxidase_2 PF01328.17 PRP85596.1 - 3.3e-37 128.8 0.0 5e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 WD40 PF00400.32 PRP85597.1 - 3.1e-29 100.6 7.7 8.6e-05 23.2 0.0 8.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Ank_4 PF13637.6 PRP85597.1 - 1.3e-12 48.0 0.1 6.4e-05 23.4 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP85597.1 - 3.8e-10 40.2 0.1 2.2e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP85597.1 - 1.1e-09 38.4 0.0 0.00058 20.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Nup160 PF11715.8 PRP85597.1 - 3.5e-09 35.9 0.5 0.023 13.4 0.0 3.8 4 0 0 4 4 4 3 Nucleoporin Nup120/160 zf-C3HC4_2 PF13923.6 PRP85597.1 - 1.3e-08 34.5 8.4 1.3e-08 34.5 8.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP85597.1 - 1.4e-08 34.5 8.3 3.4e-08 33.2 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP85597.1 - 3.9e-08 33.2 9.1 1.4e-07 31.4 9.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP85597.1 - 1e-07 31.6 7.9 2.1e-07 30.7 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP85597.1 - 1.5e-07 31.5 9.3 3.5e-07 30.3 9.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PRP85597.1 - 7e-07 29.5 9.3 7e-07 29.5 9.3 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 PRP85597.1 - 1.5e-06 28.0 8.1 3.5e-06 26.9 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Ank_3 PF13606.6 PRP85597.1 - 1.1e-05 25.4 0.1 0.0096 16.4 0.0 3.0 3 0 0 3 3 2 1 Ankyrin repeat Ank PF00023.30 PRP85597.1 - 1.2e-05 25.5 0.1 0.033 14.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat ANAPC4_WD40 PF12894.7 PRP85597.1 - 0.00013 22.1 0.2 0.97 9.8 0.0 3.8 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Prok-RING_4 PF14447.6 PRP85597.1 - 0.0014 18.4 8.5 0.0033 17.2 8.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PRP85597.1 - 0.015 15.1 4.6 0.042 13.7 4.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Nucleoporin_N PF08801.11 PRP85597.1 - 0.021 13.6 0.9 27 3.3 0.0 3.7 3 1 0 3 3 3 0 Nup133 N terminal like zf-RING_10 PF16685.5 PRP85597.1 - 0.12 12.5 5.0 0.3 11.2 5.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 PRP85597.1 - 0.16 11.8 6.6 0.32 10.8 6.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 PRP85597.1 - 0.16 11.8 8.7 0.5 10.1 8.7 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 PRP85597.1 - 0.24 11.7 11.3 0.026 14.8 4.4 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain Siva PF05458.12 PRP85597.1 - 0.37 10.4 2.1 0.88 9.2 2.1 1.6 1 0 0 1 1 1 0 Cd27 binding protein (Siva) PHF5 PF03660.14 PRP85598.1 - 1.4e-50 169.8 11.7 1.6e-50 169.7 11.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 PRP85598.1 - 0.046 11.6 7.7 0.049 11.5 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 PRP85598.1 - 3 8.0 15.2 6.9 6.8 2.3 2.9 1 1 1 2 2 2 0 Double zinc ribbon SH2 PF00017.24 PRP85599.1 - 1.8e-11 44.0 0.0 4.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 SH2 domain PTEN_C2 PF10409.9 PRP85600.1 - 1.8e-20 73.0 0.0 2.9e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 PRP85600.1 - 3.3e-06 27.0 0.0 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PRP85600.1 - 0.076 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family ELO PF01151.18 PRP85601.1 - 2e-59 201.2 15.7 2.4e-59 200.9 15.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Bac_DNA_binding PF00216.21 PRP85602.1 - 0.021 15.0 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial DNA-binding protein GTP_EFTU PF00009.27 PRP85603.1 - 1.6e-54 184.4 0.0 2.7e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PRP85603.1 - 3.2e-18 65.5 0.3 7.7e-18 64.3 0.3 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PRP85603.1 - 4.2e-08 33.5 5.1 4.9e-08 33.2 2.6 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PRP85603.1 - 6.8e-07 29.4 0.1 1.7e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 PRP85603.1 - 0.00021 20.7 0.1 0.00041 19.7 0.1 1.4 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 PRP85603.1 - 0.0028 17.2 0.3 0.031 13.8 0.3 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 PRP85603.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PRP85603.1 - 0.013 15.4 0.1 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Arf PF00025.21 PRP85603.1 - 0.023 14.1 0.1 0.096 12.1 0.1 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family Thiolase_N PF00108.23 PRP85604.1 - 3.6e-96 321.5 2.8 5.7e-96 320.9 2.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PRP85604.1 - 6e-41 138.9 0.2 1.4e-40 137.8 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PRP85604.1 - 0.00039 20.1 0.9 0.00039 20.1 0.9 1.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Aa_trans PF01490.18 PRP85605.1 - 0.00011 21.0 6.8 0.00011 21.0 6.8 2.4 1 1 1 2 2 2 1 Transmembrane amino acid transporter protein Kinase-PPPase PF03618.14 PRP85606.1 - 0.053 13.3 0.0 4.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Peptidase_A22B PF04258.13 PRP85607.1 - 2.8e-54 184.6 21.7 3.6e-54 184.2 21.7 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1126 PF06565.12 PRP85608.1 - 1.1e-85 282.3 2.0 1.5e-28 98.6 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 PRP85608.1 - 6.7e-06 26.5 0.1 2e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PRP85608.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP85608.1 - 0.049 13.6 0.0 0.71 10.0 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain GSDH PF07995.11 PRP85610.1 - 1.1e-20 74.2 0.0 2.2e-19 69.9 0.0 2.7 1 1 1 2 2 2 1 Glucose / Sorbosone dehydrogenase PKD PF00801.20 PRP85610.1 - 2.1e-17 62.7 16.4 1.3e-08 34.6 1.3 4.1 3 1 0 3 3 3 2 PKD domain SH3_1 PF00018.28 PRP85610.1 - 4.6e-11 42.1 0.1 1.2e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP85610.1 - 9.4e-09 35.0 0.0 2.3e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain LRR_6 PF13516.6 PRP85610.1 - 3.8e-08 32.8 27.2 1.7 8.9 0.2 10.3 11 0 0 11 11 11 4 Leucine Rich repeat SH3_2 PF07653.17 PRP85610.1 - 3.9e-08 32.8 0.0 9.5e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LRR_4 PF12799.7 PRP85610.1 - 3.3e-06 27.3 12.6 0.085 13.3 0.1 6.1 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP85610.1 - 0.0083 16.5 16.4 3.7 8.5 0.1 8.3 8 1 0 8 8 8 1 Leucine Rich Repeat TMEM126 PF07114.11 PRP85610.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 126 PKD_channel PF08016.12 PRP85611.1 - 8.4e-35 120.3 21.0 2.5e-34 118.7 21.0 1.7 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 PRP85611.1 - 3.1e-12 46.3 20.1 5.9e-12 45.3 20.1 1.4 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 PRP85611.1 - 1e-05 26.0 0.2 4.4e-05 24.0 0.2 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85611.1 - 0.017 15.7 0.3 0.072 13.7 0.3 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 PRP85611.1 - 0.073 13.6 0.2 0.28 11.7 0.2 2.1 1 0 0 1 1 1 0 Ankyrin repeat MOSC PF03473.17 PRP85612.1 - 5.5e-31 107.3 0.0 9e-31 106.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 PRP85612.1 - 1.5e-22 79.7 0.0 9.5e-22 77.1 0.0 2.0 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain CTP_transf_1 PF01148.20 PRP85613.1 - 4.9e-63 213.4 15.2 6.6e-63 213.0 15.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Peroxin-3 PF04882.12 PRP85613.1 - 0.32 9.9 1.0 4.8 6.1 0.1 2.0 2 0 0 2 2 2 0 Peroxin-3 DLIC PF05783.11 PRP85614.1 - 2.5e-88 297.0 12.7 7.9e-87 292.0 12.7 2.0 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 PRP85614.1 - 0.0013 18.9 0.0 0.0039 17.4 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PRP85614.1 - 0.032 14.1 1.5 3.2 7.6 0.1 2.8 3 0 0 3 3 3 0 RsgA GTPase STAT_alpha PF01017.20 PRP85614.1 - 0.43 10.5 2.6 0.3 11.0 0.1 2.0 2 1 0 2 2 2 0 STAT protein, all-alpha domain Sas10_Utp3 PF04000.15 PRP85615.1 - 8.7e-09 35.9 0.3 8.7e-09 35.9 0.3 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Pkinase PF00069.25 PRP85616.1 - 4.9e-35 121.2 0.0 9.4e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85616.1 - 1.6e-32 112.8 0.0 2.7e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.19 PRP85616.1 - 4.3e-24 85.7 0.4 1.4e-23 84.0 0.4 2.0 1 0 0 1 1 1 1 RasGEF domain Laminin_G_3 PF13385.6 PRP85616.1 - 2.2e-17 63.6 6.7 5.8e-17 62.2 6.7 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F-box-like PF12937.7 PRP85616.1 - 2.3e-07 30.6 0.1 6.3e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP85616.1 - 2.8e-06 27.1 0.1 7.6e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain Kinase-like PF14531.6 PRP85616.1 - 0.019 14.3 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Laminin_G_2 PF02210.24 PRP85616.1 - 0.05 14.2 0.4 0.17 12.5 0.4 2.0 1 0 0 1 1 1 0 Laminin G domain TMEM208_SND2 PF05620.11 PRP85617.1 - 0.098 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 PBD PF00786.28 PRP85618.1 - 8.8e-15 54.8 0.0 2e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH1 PF00568.23 PRP85618.1 - 2.6e-14 53.1 0.1 4.1e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 PRP85618.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.13 PRP85618.1 - 0.036 14.0 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family F-box PF00646.33 PRP85619.1 - 0.0098 15.8 0.2 0.025 14.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP85619.1 - 0.014 15.2 0.9 0.036 13.9 0.9 1.7 1 0 0 1 1 1 0 F-box-like CortBP2 PF09727.9 PRP85619.1 - 0.025 14.5 1.4 0.036 14.0 1.4 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 LRR_8 PF13855.6 PRP85620.1 - 1.4e-17 63.2 15.3 4.3e-06 26.4 0.1 4.0 1 1 4 5 5 5 5 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP85620.1 - 1e-15 57.7 0.0 2.2e-10 40.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PRP85620.1 - 4.1e-11 42.9 8.6 7.5e-05 23.0 2.0 4.6 2 1 2 5 5 5 5 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP85620.1 - 4.4e-10 39.4 0.0 6.1e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain LRR_9 PF14580.6 PRP85620.1 - 6.7e-06 25.7 0.6 0.0013 18.3 0.5 2.4 1 1 1 2 2 2 2 Leucine-rich repeat Kdo PF06293.14 PRP85620.1 - 9.7e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP85620.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RsmF_methylt_CI PF17126.5 PRP85620.1 - 0.05 13.7 0.0 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain CSTF_C PF14304.6 PRP85620.1 - 0.14 11.7 0.1 22 4.8 0.0 2.6 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal RIO1 PF01163.22 PRP85620.1 - 0.25 10.9 0.0 0.95 9.0 0.0 2.0 2 1 0 2 2 2 0 RIO1 family Arf PF00025.21 PRP85621.1 - 3.4e-39 134.1 0.0 4.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP85621.1 - 2.9e-11 43.2 0.0 3.7e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 PRP85621.1 - 3.7e-11 42.9 0.0 5.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP85621.1 - 2.1e-10 40.9 0.0 3.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PRP85621.1 - 1.1e-07 31.3 0.0 3.4e-06 26.4 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 PRP85621.1 - 3.3e-06 26.7 0.0 4.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PRP85621.1 - 5.5e-06 26.4 0.0 9.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP85621.1 - 0.0003 20.4 0.1 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain YmdB PF13277.6 PRP85621.1 - 0.092 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein Transket_pyr PF02779.24 PRP85622.1 - 3e-43 147.6 0.0 4.2e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PRP85622.1 - 8.7e-31 106.4 0.0 1.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Thiamine_BP PF01910.17 PRP85622.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Thiamine-binding protein Laminin_G_3 PF13385.6 PRP85623.1 - 5.4e-36 124.0 1.0 3e-20 72.9 0.0 2.7 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Toxin_R_bind_N PF07953.12 PRP85623.1 - 0.00012 21.9 0.5 0.11 12.2 0.0 2.9 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding DUF4982 PF16355.5 PRP85623.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) Carb_bind PF10645.9 PRP85623.1 - 5.5 7.3 33.9 0.68 10.2 4.3 4.1 3 1 1 4 4 4 0 Carbohydrate binding SNF2_N PF00176.23 PRP85625.1 - 1.9e-48 165.0 0.1 1.9e-48 165.0 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP85625.1 - 2.8e-19 69.5 0.1 6.6e-18 65.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 PRP85625.1 - 5.2e-07 29.7 0.1 2.4e-06 27.6 0.1 2.2 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal ERCC3_RAD25_C PF16203.5 PRP85625.1 - 5.9e-06 25.7 0.1 5.9e-06 25.7 0.1 2.7 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 PRP85625.1 - 0.003 17.4 0.0 0.0097 15.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Med14 PF08638.11 PRP85626.1 - 4.7e-34 117.5 0.0 9.6e-33 113.2 0.0 2.7 1 1 0 1 1 1 1 Mediator complex subunit MED14 Diphthamide_syn PF01866.17 PRP85627.1 - 3.1e-110 368.4 0.0 4e-110 368.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SAP PF02037.27 PRP85628.1 - 4.1e-09 36.0 1.7 1.4e-08 34.3 1.7 2.0 1 0 0 1 1 1 1 SAP domain DUF3450 PF11932.8 PRP85628.1 - 0.0043 16.4 6.9 0.0043 16.4 6.9 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3450) Fez1 PF06818.15 PRP85628.1 - 0.0045 17.5 6.5 0.0045 17.5 6.5 2.7 2 0 0 2 2 2 1 Fez1 Flagellin_C PF00700.21 PRP85628.1 - 0.016 15.5 1.0 0.041 14.2 1.0 1.7 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Bacillus_HBL PF05791.11 PRP85628.1 - 0.13 12.0 7.7 0.43 10.4 7.7 1.8 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Exonuc_VII_L PF02601.15 PRP85628.1 - 0.16 11.5 10.8 0.26 10.8 9.9 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 PRP85628.1 - 9.6 5.5 32.2 0.34 10.2 24.9 1.9 2 0 0 2 2 2 0 FAM76 protein Pkinase PF00069.25 PRP85630.1 - 1.6e-67 227.7 0.0 2.9e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85630.1 - 3e-33 115.2 0.0 6e-33 114.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP85630.1 - 1.7e-19 70.2 0.3 4.1e-19 69.0 0.3 1.7 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 PRP85630.1 - 2.3e-06 27.6 0.2 7.6e-06 26.0 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP85630.1 - 3.6e-06 27.3 1.2 2.5e-05 24.6 1.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain FTA2 PF13095.6 PRP85630.1 - 0.0059 16.2 0.0 0.87 9.2 0.0 2.6 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PH_6 PF15406.6 PRP85630.1 - 0.006 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 PRP85630.1 - 0.015 14.6 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Ribosomal_S10 PF00338.22 PRP85630.1 - 0.034 14.4 0.1 6.2 7.1 0.1 3.7 3 0 0 3 3 3 0 Ribosomal protein S10p/S20e Ras PF00071.22 PRP85631.1 - 1.8e-45 154.5 0.2 2.3e-45 154.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP85631.1 - 1.5e-30 105.9 0.1 2.2e-30 105.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP85631.1 - 9.5e-11 41.5 0.1 1.1e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP85631.1 - 5.4e-08 32.5 0.2 7.6e-08 32.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP85631.1 - 1.5e-07 31.4 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP85631.1 - 4.3e-05 23.5 0.0 0.00014 21.8 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PRP85631.1 - 6.1e-05 22.6 0.1 0.00049 19.7 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MCM PF00493.23 PRP85631.1 - 7e-05 22.0 0.0 0.028 13.5 0.0 2.2 2 0 0 2 2 2 2 MCM P-loop domain DAP3 PF10236.9 PRP85631.1 - 0.003 16.8 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 PRP85631.1 - 0.0062 16.8 0.0 0.038 14.3 0.0 1.9 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP85631.1 - 0.0068 16.8 0.0 0.009 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 PRP85631.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 PRP85631.1 - 0.022 14.8 0.0 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 PRP85631.1 - 0.028 13.6 0.2 0.042 13.0 0.2 1.4 1 1 0 1 1 1 0 G-protein alpha subunit Sigma54_activat PF00158.26 PRP85631.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 PRP85631.1 - 0.054 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 PRP85631.1 - 0.091 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 PRP85631.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PRP85631.1 - 0.11 13.0 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 PRP85631.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RNB PF00773.19 PRP85632.1 - 1.5e-56 192.1 0.3 1.1e-55 189.3 0.3 2.1 1 1 0 1 1 1 1 RNB domain MaoC_dehydratas PF01575.19 PRP85633.1 - 4.5e-28 97.3 0.0 3.8e-27 94.3 0.0 2.2 3 0 0 3 3 3 1 MaoC like domain MaoC_dehydrat_N PF13452.6 PRP85633.1 - 1.7e-09 37.9 0.0 9e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Fumarate_red_D PF02313.17 PRP85634.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit D Voldacs PF03517.13 PRP85635.1 - 2.3e-18 66.7 1.1 2.7e-09 37.3 0.1 2.3 1 1 1 2 2 2 2 Regulator of volume decrease after cellular swelling BBL5 PF07289.11 PRP85635.1 - 0.065 12.3 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein adh_short PF00106.25 PRP85636.1 - 1e-27 96.8 3.0 2.3e-23 82.7 0.2 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP85636.1 - 3.7e-15 56.1 1.5 1.5e-12 47.6 0.1 2.6 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Ureide_permease PF07168.11 PRP85636.1 - 0.039 12.7 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 Ureide permease HP1451_C PF18472.1 PRP85636.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 HP1451 C-terminal domain LRR_9 PF14580.6 PRP85637.1 - 1.2e-11 44.4 0.9 2.1e-11 43.7 0.9 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PRP85637.1 - 1.8e-06 28.1 8.6 0.00083 19.7 3.3 3.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP85637.1 - 0.0011 18.7 1.9 0.0011 18.7 1.9 3.1 3 1 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 PRP85637.1 - 0.016 15.2 3.1 2.2 8.6 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat TbpB_C PF17483.2 PRP85637.1 - 0.052 13.9 0.7 0.1 12.9 0.2 1.8 2 0 0 2 2 2 0 C-lobe handle domain of Tf-binding protein B CaiF_GrlA PF07180.11 PRP85637.1 - 0.11 12.4 0.3 0.38 10.7 0.3 1.8 1 1 0 1 1 1 0 CaiF/GrlA transcriptional regulator EMP24_GP25L PF01105.24 PRP85639.1 - 0.075 13.0 0.0 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD C2-set_2 PF08205.12 PRP85640.1 - 0.034 14.2 0.1 0.094 12.8 0.1 1.7 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Vac14_Fab1_bd PF12755.7 PRP85640.1 - 0.079 13.6 0.2 0.71 10.5 0.0 2.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region YniB PF14002.6 PRP85640.1 - 1.3 8.7 3.8 1.9 8.2 0.2 2.5 3 0 0 3 3 3 0 YniB-like protein Exo_endo_phos_2 PF14529.6 PRP85644.1 - 1.1e-07 31.7 2.2 1.5e-07 31.3 0.1 2.4 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 PRP85644.1 - 3.5e-05 23.4 0.0 9.8e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0172 PF03665.13 PRP85644.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0172) RT_RNaseH PF17917.1 PRP85645.1 - 3.4e-33 114.1 0.0 6.7e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 PRP85645.1 - 4.5e-33 113.3 0.0 1.9e-32 111.3 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 PRP85645.1 - 4.7e-21 74.7 0.1 8.9e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 PRP85645.1 - 3.4e-13 49.8 0.7 1.9e-12 47.4 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.24 PRP85645.1 - 2.6e-07 30.5 0.9 6.7e-07 29.1 0.9 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.10 PRP85645.1 - 3e-06 27.4 0.0 5.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger RVT_1 PF00078.27 PRP85646.1 - 2.4e-08 33.8 0.0 2.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 PRP85647.1 - 1.8e-07 31.7 0.0 4.4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PRP85647.1 - 7.1e-06 26.5 0.0 1.8e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 PRP85647.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.27 PRP85647.1 - 0.012 15.1 0.1 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.23 PRP85647.1 - 0.041 14.0 5.2 0.092 12.9 5.2 1.6 1 0 0 1 1 1 0 Zinc knuckle dsDNA_bind PF01984.20 PRP85647.1 - 0.045 14.0 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain LRR_8 PF13855.6 PRP85648.1 - 3.6e-43 145.1 61.7 1.3e-08 34.4 5.3 8.6 6 2 2 8 8 8 8 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP85648.1 - 4e-41 141.0 4.6 1.9e-25 89.7 0.6 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 PRP85648.1 - 1.5e-38 132.7 5.4 1.4e-22 80.4 0.7 3.2 2 1 1 3 3 3 3 Protein kinase domain LRR_4 PF12799.7 PRP85648.1 - 8.5e-27 92.8 61.4 0.00029 21.2 1.1 10.8 7 1 1 10 10 10 9 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP85648.1 - 2e-22 79.4 15.5 6.1e-11 42.7 4.2 2.7 2 0 0 2 2 2 2 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP85648.1 - 0.00049 20.3 59.2 0.28 11.9 0.1 15.8 15 2 1 16 16 14 1 Leucine Rich Repeat Syndecan PF01034.20 PRP85648.1 - 0.0012 18.7 7.6 0.17 11.8 0.2 2.6 2 0 0 2 2 2 2 Syndecan domain LapA_dom PF06305.11 PRP85648.1 - 0.0038 17.0 0.2 4.1 7.3 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain TMEM61 PF15105.6 PRP85648.1 - 0.0042 16.9 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 1 TMEM61 protein family CD34_antigen PF06365.12 PRP85648.1 - 0.028 14.0 1.7 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 CD34/Podocalyxin family ASTN_2_hairpin PF18577.1 PRP85648.1 - 0.082 13.0 0.0 27 5.0 0.0 2.6 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain DUF659 PF04937.15 PRP85648.1 - 0.13 12.2 1.5 7.7 6.4 0.0 2.9 3 0 0 3 3 2 0 Protein of unknown function (DUF 659) NEMO PF11577.8 PRP85648.1 - 0.16 12.0 0.1 17 5.5 0.0 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Papilloma_E5A PF05776.12 PRP85648.1 - 0.23 11.8 4.5 7.2 7.0 0.1 2.8 2 0 0 2 2 2 0 Papillomavirus E5A protein SIT PF15330.6 PRP85648.1 - 0.56 10.7 2.2 19 5.8 0.0 2.4 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1024 PF06260.12 PRP85648.1 - 0.58 10.5 2.0 21 5.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1024) Sigma_reg_N PF13800.6 PRP85648.1 - 3.2 8.1 6.8 6.7 7.1 0.4 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TMEM154 PF15102.6 PRP85648.1 - 4.9 7.1 15.7 0.19 11.7 0.4 3.3 3 1 1 4 4 4 0 TMEM154 protein family Pkinase_Tyr PF07714.17 PRP85650.1 - 1.8e-42 145.4 4.2 5.3e-27 94.7 1.1 3.4 2 2 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 PRP85650.1 - 8e-38 130.3 2.2 3.3e-23 82.4 0.3 3.4 2 1 1 3 3 3 3 Protein kinase domain LRR_8 PF13855.6 PRP85650.1 - 5.3e-28 96.6 28.8 1.8e-10 40.4 3.1 4.6 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PRP85650.1 - 2.4e-21 75.5 29.5 2.9e-05 24.3 2.2 5.8 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP85650.1 - 1.1e-10 41.9 5.2 3e-10 40.5 5.2 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP85650.1 - 6.9e-07 29.0 23.6 6.9 7.6 0.0 9.5 8 1 1 9 9 9 4 Leucine Rich Repeat PAP2_3 PF14378.6 PRP85650.1 - 0.0043 16.8 0.2 1.3 8.7 0.1 2.7 2 0 0 2 2 2 2 PAP2 superfamily Cupin_8 PF13621.6 PRP85651.1 - 2.9e-13 50.1 0.1 4e-10 39.8 0.1 2.2 2 0 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 PRP85651.1 - 8.8e-07 28.7 0.1 1.7e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PRP85651.1 - 0.00026 21.4 0.0 0.00096 19.6 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 PRP85651.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 PRP85651.1 - 0.12 12.1 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Lipase PF00151.19 PRP85652.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Lipase Utp12 PF04003.12 PRP85653.1 - 1.9e-15 57.0 2.9 1.9e-15 57.0 2.9 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40 PF00400.32 PRP85653.1 - 4.3e-14 52.7 0.4 4.3e-05 24.2 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP85653.1 - 3.2e-07 30.5 0.4 0.29 11.5 0.0 4.7 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 PRP85653.1 - 0.36 11.0 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL41A MORN PF02493.20 PRP85654.1 - 2.6e-33 111.9 47.1 1.5e-08 34.0 1.9 8.8 8 0 0 8 8 8 8 MORN repeat UQ_con PF00179.26 PRP85654.1 - 5.6e-09 35.8 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RING_2 PF13639.6 PRP85654.1 - 0.00016 21.9 7.9 0.00016 21.9 7.9 3.6 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 PRP85654.1 - 0.00033 20.6 9.2 0.00033 20.6 9.2 3.1 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PRP85654.1 - 0.0006 19.6 6.8 0.0006 19.6 6.8 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 PRP85654.1 - 0.0019 18.0 0.6 0.0046 16.8 0.6 1.6 1 0 0 1 1 1 1 F-box-like Laminin_G_3 PF13385.6 PRP85654.1 - 0.0026 17.9 0.6 2.2 8.4 0.0 2.6 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Prok-E2_B PF14461.6 PRP85654.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-RING_UBOX PF13445.6 PRP85654.1 - 0.0058 16.6 5.3 0.0058 16.6 5.3 3.7 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PRP85654.1 - 0.028 14.3 8.5 0.97 9.3 5.5 3.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 CCDC50_N PF15295.6 PRP85654.1 - 0.04 14.1 2.4 0.084 13.0 2.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus F-box PF00646.33 PRP85654.1 - 0.041 13.8 1.6 0.083 12.8 1.6 1.6 1 0 0 1 1 1 0 F-box domain zf-C3HC4_2 PF13923.6 PRP85654.1 - 0.16 11.8 12.3 0.2 11.5 5.9 3.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Carb_bind PF10645.9 PRP85654.1 - 3.5 7.9 22.4 0.97 9.7 4.4 3.3 2 1 1 3 3 3 0 Carbohydrate binding zf-C3HC4_4 PF15227.6 PRP85654.1 - 4.4 7.5 9.0 0.16 12.2 0.7 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Holin_SPP1 PF04688.13 PRP85655.1 - 0.6 10.3 3.3 2.1 8.6 0.3 2.5 2 1 0 2 2 2 0 SPP1 phage holin IL6 PF00489.17 PRP85656.1 - 0.00052 19.6 0.4 0.00099 18.7 0.4 1.4 1 1 0 1 1 1 1 Interleukin-6/G-CSF/MGF family DUF3043 PF11241.8 PRP85657.1 - 1 9.4 7.1 0.41 10.7 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) RNase_H PF00075.24 PRP85658.1 - 4e-39 134.1 0.4 7.1e-38 130.0 0.0 2.6 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.6 PRP85658.1 - 0.0085 15.9 0.3 0.042 13.7 0.0 2.2 3 0 0 3 3 3 1 Reverse transcriptase-like Ank_2 PF12796.7 PRP85659.1 - 4e-47 158.7 0.0 3.7e-11 43.5 0.0 5.0 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85659.1 - 6.3e-39 131.9 0.5 6.7e-07 29.7 0.0 8.5 2 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 PRP85659.1 - 2.5e-26 90.9 0.4 0.023 15.1 0.0 10.1 9 2 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 PRP85659.1 - 6.9e-22 77.2 0.1 0.022 15.1 0.0 9.9 3 2 7 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85659.1 - 2.2e-21 73.6 0.3 0.25 12.0 0.1 9.8 10 0 0 10 10 10 4 Ankyrin repeat VWA_3_C PF18571.1 PRP85659.1 - 0.014 15.2 6.6 83 3.2 0.0 6.6 6 1 1 7 7 7 0 von Willebrand factor type A C-terminal domain Hairy_orange PF07527.13 PRP85659.1 - 0.24 11.6 7.2 73 3.7 0.0 6.7 10 0 0 10 10 10 0 Hairy Orange DUF5127 PF17168.4 PRP85660.1 - 4.9e-54 183.5 3.6 8.2e-54 182.8 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 PRP85660.1 - 3.2e-46 157.2 0.0 1.3e-40 138.9 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF1793 PF08760.11 PRP85660.1 - 5.9e-39 134.2 1.5 1.6e-38 132.8 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 PRP85660.1 - 1.6e-20 72.5 0.1 4.6e-20 71.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) PAN_4 PF14295.6 PRP85660.1 - 1.5e-10 40.8 6.0 3.2e-10 39.8 6.0 1.6 1 0 0 1 1 1 1 PAN domain Glyco_hydr_116N PF12215.8 PRP85660.1 - 4.8e-05 23.0 0.4 0.00022 20.8 0.4 1.9 1 1 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term PAN_1 PF00024.26 PRP85660.1 - 6.8e-05 22.7 3.2 0.00014 21.7 3.2 1.5 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP85660.1 - 0.11 12.6 3.7 0.26 11.4 3.7 1.6 1 0 0 1 1 1 0 PAN-like domain SET PF00856.28 PRP85661.1 - 3e-13 50.5 0.2 3e-13 50.5 0.2 4.8 2 1 0 2 2 2 1 SET domain Filamin PF00630.19 PRP85661.1 - 0.00016 22.4 22.6 0.012 16.4 0.1 4.5 4 1 0 4 4 4 1 Filamin/ABP280 repeat Big_1 PF02369.16 PRP85661.1 - 0.0068 16.4 0.7 0.026 14.5 0.0 2.5 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 1) Invasin_D3 PF09134.10 PRP85661.1 - 0.032 14.5 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 0 Invasin, domain 3 FYVE PF01363.21 PRP85661.1 - 1.6 8.9 12.7 5.7 7.1 12.7 1.9 1 0 0 1 1 1 0 FYVE zinc finger Laminin_G_3 PF13385.6 PRP85662.1 - 9.8e-26 90.7 10.3 2.1e-14 54.0 0.6 3.4 2 1 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily UQ_con PF00179.26 PRP85662.1 - 1.5e-07 31.1 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Toxin_R_bind_N PF07953.12 PRP85662.1 - 2e-05 24.4 1.8 0.032 13.9 0.4 3.4 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding zf-RING_2 PF13639.6 PRP85662.1 - 0.00015 22.1 7.9 0.00015 22.1 7.9 3.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PRP85662.1 - 0.0003 20.7 9.2 0.0003 20.7 9.2 3.3 4 0 0 4 4 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PRP85662.1 - 0.00044 20.1 11.9 0.00055 19.7 6.8 3.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-E2_B PF14461.6 PRP85662.1 - 0.0033 17.1 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-RING_UBOX PF13445.6 PRP85662.1 - 0.0053 16.7 5.3 0.0053 16.7 5.3 3.8 3 0 0 3 3 3 1 RING-type zinc-finger CCDC50_N PF15295.6 PRP85662.1 - 0.044 14.0 2.4 0.077 13.2 2.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Prok-RING_4 PF14447.6 PRP85662.1 - 0.2 11.6 12.1 0.89 9.5 5.5 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PRP85662.1 - 0.43 10.5 14.4 0.19 11.6 5.9 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Utp12 PF04003.12 PRP85663.1 - 1.9e-15 57.0 2.9 1.9e-15 57.0 2.9 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40 PF00400.32 PRP85663.1 - 4.3e-14 52.7 0.4 4.3e-05 24.2 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP85663.1 - 3.2e-07 30.5 0.4 0.29 11.5 0.0 4.7 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 PRP85663.1 - 0.36 11.0 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus UL41A Cupin_8 PF13621.6 PRP85664.1 - 2.5e-13 50.3 0.1 3.6e-10 40.0 0.1 2.2 2 0 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 PRP85664.1 - 8.3e-07 28.8 0.1 1.6e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PRP85664.1 - 0.0003 21.2 0.0 0.00088 19.7 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 PRP85664.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 PRP85664.1 - 0.12 12.1 0.1 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Cupin domain LRR_8 PF13855.6 PRP85665.1 - 5.2e-33 112.6 51.9 9.5e-09 34.9 2.5 7.3 1 1 6 8 8 8 8 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP85665.1 - 4.1e-30 104.9 0.4 6.8e-30 104.2 0.4 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85665.1 - 1.2e-27 97.0 0.5 2.1e-27 96.1 0.5 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP85665.1 - 4.5e-25 87.3 53.0 4e-05 23.9 1.8 8.9 6 2 2 9 9 9 9 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP85665.1 - 1.6e-10 41.3 3.3 5.3e-10 39.7 3.3 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP85665.1 - 0.0081 16.6 55.5 8.8 7.3 0.3 14.8 16 1 0 16 16 16 2 Leucine Rich Repeat TMEM154 PF15102.6 PRP85665.1 - 0.043 13.7 0.1 0.043 13.7 0.1 6.0 2 1 0 2 2 2 0 TMEM154 protein family Syndecan PF01034.20 PRP85665.1 - 0.047 13.6 0.3 0.12 12.3 0.3 1.6 1 0 0 1 1 1 0 Syndecan domain LRR_8 PF13855.6 PRP85666.1 - 5.3e-35 119.0 55.9 1.6e-08 34.2 3.3 8.1 4 2 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 PRP85666.1 - 1.6e-19 69.7 54.4 0.0019 18.6 1.9 8.7 3 2 2 8 8 8 7 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP85666.1 - 1.3e-10 41.6 3.1 3.9e-10 40.1 3.1 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Syndecan PF01034.20 PRP85666.1 - 0.00021 21.2 0.2 0.00053 19.8 0.2 1.6 1 0 0 1 1 1 1 Syndecan domain TMEM154 PF15102.6 PRP85666.1 - 0.0019 18.1 0.2 0.0019 18.1 0.2 3.0 2 1 1 3 3 2 1 TMEM154 protein family LRR_1 PF00560.33 PRP85666.1 - 0.0089 16.4 54.5 9.9 7.2 0.1 13.8 14 0 0 14 14 13 2 Leucine Rich Repeat DUF659 PF04937.15 PRP85666.1 - 0.019 14.8 0.1 0.046 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) DUF211 PF02680.14 PRP85666.1 - 0.034 14.3 0.2 0.083 13.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 MitoNEET_N PF10660.9 PRP85666.1 - 0.09 12.8 6.5 72 3.5 0.0 5.9 5 1 1 6 6 6 0 Iron-containing outer mitochondrial membrane protein N-terminus LapA_dom PF06305.11 PRP85666.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Apt1 PF10351.9 PRP85666.1 - 1.2 7.9 15.8 2.1 7.1 15.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain LRR_6 PF13516.6 PRP85666.1 - 1.3 9.2 45.4 9 6.6 0.0 11.3 12 0 0 12 12 12 0 Leucine Rich repeat Chordopox_A13L PF05961.11 PRP85666.1 - 2 8.7 4.2 17 5.8 4.2 2.6 1 1 0 1 1 1 0 Chordopoxvirus A13L protein LRR_8 PF13855.6 PRP85667.1 - 3.1e-44 148.5 71.1 1.1e-09 37.9 2.7 8.4 2 2 7 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 PRP85667.1 - 8.3e-33 111.9 65.5 5.4e-06 26.7 0.8 9.4 5 2 4 10 10 10 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP85667.1 - 1e-13 49.7 60.0 0.57 10.9 0.1 15.3 15 0 0 15 15 15 3 Leucine Rich Repeat GPS PF01825.21 PRP85667.1 - 1.2e-10 41.7 3.1 4.2e-10 40.0 3.1 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Syndecan PF01034.20 PRP85667.1 - 0.0052 16.7 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain SOG2 PF10428.9 PRP85667.1 - 0.0068 15.7 37.1 0.012 14.9 37.1 1.4 1 0 0 1 1 1 1 RAM signalling pathway protein TMEM154 PF15102.6 PRP85667.1 - 0.0078 16.1 0.2 0.0078 16.1 0.2 4.6 2 1 2 4 4 2 1 TMEM154 protein family DUF659 PF04937.15 PRP85667.1 - 0.029 14.2 1.2 0.05 13.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) LRR_9 PF14580.6 PRP85667.1 - 0.057 12.9 11.5 1.7 8.1 0.1 4.8 2 2 2 5 5 5 0 Leucine-rich repeat FAM76 PF16046.5 PRP85667.1 - 0.47 9.7 8.3 1.1 8.6 8.3 1.6 1 0 0 1 1 1 0 FAM76 protein SOBP PF15279.6 PRP85667.1 - 5.8 7.4 15.8 9.8 6.7 15.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Pkinase_Tyr PF07714.17 PRP85669.1 - 7.6e-23 81.1 1.0 2e-22 79.7 1.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85669.1 - 5.6e-18 65.2 0.9 2.9e-17 62.9 0.9 1.9 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP85669.1 - 5.1e-16 58.2 26.7 1.4e-05 24.8 2.1 4.9 3 1 2 5 5 5 4 Leucine rich repeat GPS PF01825.21 PRP85669.1 - 3.6e-12 46.6 5.4 9.3e-12 45.3 5.4 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP85669.1 - 7.7e-12 45.2 29.8 4.8e-05 23.6 1.2 6.4 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) Syndecan PF01034.20 PRP85669.1 - 0.12 12.4 0.4 0.25 11.3 0.4 1.5 1 0 0 1 1 1 0 Syndecan domain LRR_1 PF00560.33 PRP85669.1 - 0.39 11.5 29.6 6.3 7.8 0.5 8.0 8 1 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 PRP85670.1 - 2.5e-28 97.6 29.8 1.3e-08 34.4 3.5 4.5 3 1 1 4 4 4 4 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP85670.1 - 9.6e-28 97.2 0.6 1.9e-27 96.2 0.6 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85670.1 - 7.4e-25 87.8 0.2 1.3e-24 87.0 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP85670.1 - 6.2e-22 77.3 30.0 1.7e-05 25.0 1.9 5.7 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP85670.1 - 1.8e-10 41.2 4.0 4.9e-10 39.8 4.0 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP85670.1 - 2.1e-07 30.5 24.1 3.4 8.6 1.0 9.3 8 1 1 9 9 9 2 Leucine Rich Repeat MukB PF04310.12 PRP85670.1 - 0.0043 16.9 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 MukB N-terminal Syndecan PF01034.20 PRP85670.1 - 0.18 11.8 0.2 0.51 10.3 0.2 1.7 1 0 0 1 1 1 0 Syndecan domain LRR_8 PF13855.6 PRP85671.1 - 7e-59 195.5 100.5 2.7e-08 33.4 3.0 12.6 5 3 5 13 13 13 13 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP85671.1 - 8.1e-54 182.6 3.0 3.8e-26 91.9 0.7 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP85671.1 - 3.7e-49 167.5 2.8 1.8e-24 86.5 0.5 2.2 2 0 0 2 2 2 2 Protein kinase domain LRR_4 PF12799.7 PRP85671.1 - 3.2e-33 113.2 105.8 6.2e-06 26.5 0.6 15.7 4 3 15 21 21 20 17 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP85671.1 - 5.8e-21 74.8 17.2 2.6e-10 40.7 4.5 2.7 2 0 0 2 2 2 2 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP85671.1 - 5e-09 35.5 91.9 0.098 13.3 0.3 22.6 23 2 1 24 24 22 4 Leucine Rich Repeat DUF659 PF04937.15 PRP85671.1 - 0.00055 19.8 0.0 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF 659) Syndecan PF01034.20 PRP85671.1 - 0.0043 16.9 10.4 0.013 15.4 0.5 3.0 3 0 0 3 3 3 2 Syndecan domain LapA_dom PF06305.11 PRP85671.1 - 0.0044 16.8 0.1 2.7 7.9 0.0 2.7 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain DUF211 PF02680.14 PRP85671.1 - 0.041 14.1 1.7 0.2 11.9 0.2 3.0 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 DUF4448 PF14610.6 PRP85671.1 - 0.055 13.2 0.4 1.9 8.3 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) ASTN_2_hairpin PF18577.1 PRP85671.1 - 0.14 12.3 0.1 36 4.6 0.0 2.7 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain Papilloma_E5A PF05776.12 PRP85671.1 - 0.16 12.4 3.6 3.2 8.2 1.0 2.7 2 0 0 2 2 2 0 Papillomavirus E5A protein CD34_antigen PF06365.12 PRP85671.1 - 0.23 11.0 1.4 14 5.2 0.1 2.4 2 0 0 2 2 2 0 CD34/Podocalyxin family adh_short PF00106.25 PRP85673.1 - 1.1e-46 158.7 0.3 1.1e-46 158.7 0.3 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP85673.1 - 1.8e-33 116.1 0.1 1.8e-33 116.1 0.1 2.6 2 2 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP85673.1 - 3.7e-09 36.7 0.1 8e-09 35.7 0.1 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP85673.1 - 2.2e-05 24.0 0.0 9.7e-05 21.9 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 PRP85673.1 - 0.0057 16.0 0.2 0.013 14.8 0.2 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3405 PF11885.8 PRP85674.1 - 5.7e-09 35.1 0.4 1.4e-08 33.9 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) DUF3670 PF12419.8 PRP85674.1 - 0.0039 17.0 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 Helicase protein TatD_DNase PF01026.21 PRP85675.1 - 2.6e-56 190.8 0.0 3.1e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 PRP85675.1 - 1.1e-05 25.4 0.1 0.00011 22.1 0.0 2.6 1 1 0 2 2 2 1 Amidohydrolase Rdx PF10262.9 PRP85676.1 - 0.0002 21.5 0.0 0.00026 21.1 0.0 1.1 1 0 0 1 1 1 1 Rdx family DinI PF06183.13 PRP85676.1 - 0.0094 16.3 0.1 0.044 14.1 0.0 2.0 3 0 0 3 3 3 1 DinI-like family adh_short PF00106.25 PRP85677.1 - 1.7e-27 96.2 0.3 2.1e-27 95.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP85677.1 - 1.3e-25 90.4 1.6 1.7e-25 90.0 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP85677.1 - 3.5e-09 36.8 0.4 4.3e-09 36.5 0.4 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP85677.1 - 2e-05 24.6 2.9 0.00011 22.2 2.9 2.1 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 PRP85678.1 - 1.5e-28 99.6 0.2 1.8e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP85678.1 - 1.9e-26 93.0 1.6 2.5e-26 92.7 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP85678.1 - 3.9e-09 36.7 0.3 4.8e-09 36.4 0.3 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP85678.1 - 0.00012 22.0 1.5 0.00018 21.5 1.5 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Mfa_like_2 PF15415.6 PRP85678.1 - 0.037 12.9 0.0 0.19 10.6 0.0 1.8 1 1 1 2 2 2 0 Fimbrillin-like GDP_Man_Dehyd PF16363.5 PRP85678.1 - 0.082 12.3 0.3 0.13 11.6 0.3 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Thioredoxin PF00085.20 PRP85679.1 - 6e-13 48.7 0.0 7.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PRP85679.1 - 0.0015 17.9 0.2 0.0019 17.6 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 PRP85679.1 - 0.0082 16.4 0.1 1.2 9.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PRP85679.1 - 0.037 14.5 0.0 0.39 11.2 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 PRP85679.1 - 0.043 13.6 0.0 0.069 12.9 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin Antimicrobial12 PF08107.11 PRP85679.1 - 0.09 12.6 1.8 0.86 9.4 0.9 2.6 2 0 0 2 2 2 0 Pleurocidin family Thioredoxin_7 PF13899.6 PRP85679.1 - 0.12 12.6 0.1 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Rad51 PF08423.11 PRP85681.1 - 4.7e-37 127.6 0.2 1.8e-36 125.8 0.2 1.7 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PRP85681.1 - 3e-09 36.7 0.1 5.6e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 PRP85681.1 - 8.2e-08 31.9 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 PRP85681.1 - 5.6e-06 25.9 0.3 1.3e-05 24.7 0.3 1.6 1 1 0 1 1 1 1 KaiC AAA_33 PF13671.6 PRP85681.1 - 0.0098 16.1 0.0 0.028 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Dioxygenase_N PF04444.14 PRP85681.1 - 0.028 14.3 0.2 0.38 10.7 0.1 2.6 2 0 0 2 2 2 0 Catechol dioxygenase N terminus AAA_24 PF13479.6 PRP85681.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain GGA_N-GAT PF18308.1 PRP85681.1 - 0.039 13.6 0.0 0.09 12.4 0.0 1.6 1 0 0 1 1 1 0 GGA N-GAT domain IstB_IS21 PF01695.17 PRP85681.1 - 0.055 13.2 0.3 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.29 PRP85681.1 - 0.067 13.6 0.1 0.17 12.3 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 PRP85682.1 - 9.9e-09 35.7 0.6 0.41 11.6 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat DarT PF14487.6 PRP85682.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 ssDNA thymidine ADP-ribosyltransferase, DarT SH2 PF00017.24 PRP85683.1 - 5.3e-14 52.1 0.0 8.5e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 PRP85683.1 - 2.1e-05 24.0 0.0 3.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 SH2 domain Acetyltransf_1 PF00583.25 PRP85684.1 - 2e-06 28.0 0.3 3.9e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP85684.1 - 0.00012 22.5 0.0 0.00061 20.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP85684.1 - 0.00031 20.6 0.2 0.13 12.2 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_10 PF13673.7 PRP85684.1 - 0.00056 19.8 0.1 0.043 13.8 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP85684.1 - 0.019 15.0 0.0 0.086 12.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Histone PF00125.24 PRP85685.1 - 1.1e-36 126.1 0.7 1.3e-36 125.9 0.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PRP85685.1 - 0.0001 22.9 0.3 0.0001 22.9 0.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain adh_short PF00106.25 PRP85686.1 - 1.9e-30 105.8 0.2 2.4e-30 105.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP85686.1 - 9.6e-25 87.5 0.4 1.3e-24 87.1 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP85686.1 - 1.3e-09 38.2 0.2 1.7e-09 37.9 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP85686.1 - 5.5e-06 26.4 1.5 1.4e-05 25.1 1.5 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PRP85686.1 - 0.00022 20.8 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP85686.1 - 0.00087 18.8 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 PRP85686.1 - 0.031 14.2 0.0 0.061 13.3 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MORN PF02493.20 PRP85687.1 - 3.6e-62 202.7 99.5 8.1e-07 28.6 2.6 14.8 14 0 0 14 14 14 13 MORN repeat TRAF6_Z2 PF18048.1 PRP85687.1 - 0.0095 16.0 0.3 0.023 14.8 0.3 1.6 1 0 0 1 1 1 1 TNF receptor-associated factor 6 zinc finger 2 DUF3048_C PF17479.2 PRP85687.1 - 0.03 14.7 15.5 1.3 9.5 1.9 5.1 2 2 2 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain zf-C2HC_2 PF13913.6 PRP85687.1 - 0.06 13.3 0.3 0.1 12.6 0.3 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FYDLN_acid PF09538.10 PRP85687.1 - 0.11 13.2 0.9 0.19 12.4 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Coiled PF05710.12 PRP85687.1 - 1.3 9.9 3.9 0.46 11.3 0.3 2.0 2 0 0 2 2 2 0 Coiled coil CopK PF11525.8 PRP85687.1 - 2.4 7.9 5.2 5.5 6.7 0.1 3.2 3 0 0 3 3 3 0 Copper resistance protein K Peptidase_C12 PF01088.21 PRP85688.1 - 3.4e-66 223.0 0.3 8.6e-66 221.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 PRP85688.1 - 1.7e-21 75.8 2.3 1.7e-21 75.8 2.3 2.3 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolases CENP-Q PF13094.6 PRP85688.1 - 0.0015 18.7 4.6 0.0026 18.0 4.6 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Rh5 PF18515.1 PRP85688.1 - 0.012 15.0 4.8 0.017 14.4 4.8 1.2 1 0 0 1 1 1 0 Rh5 coiled-coil domain Phage_GP20 PF06810.11 PRP85688.1 - 0.064 13.1 8.3 0.12 12.2 8.3 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 CCDC-167 PF15188.6 PRP85688.1 - 0.11 12.9 5.8 0.26 11.6 5.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Fzo_mitofusin PF04799.13 PRP85688.1 - 0.69 9.5 4.5 0.45 10.1 2.7 1.6 2 0 0 2 2 2 0 fzo-like conserved region COX16 PF14138.6 PRP85688.1 - 3.9 8.1 6.3 8.3 7.0 6.3 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Nas2_N PF18265.1 PRP85688.1 - 6.7 6.7 6.8 5.7 6.9 1.7 2.5 1 1 1 2 2 2 0 Nas2 N_terminal domain F-box-like PF12937.7 PRP85689.1 - 0.031 14.1 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like Pkinase_Tyr PF07714.17 PRP85691.1 - 2.5e-75 253.1 0.0 3.8e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85691.1 - 1.8e-39 135.7 0.0 2.8e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP85691.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like GPS PF01825.21 PRP85691.1 - 0.041 14.4 0.2 0.11 13.1 0.2 1.8 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif LapA_dom PF06305.11 PRP85691.1 - 0.068 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain APH PF01636.23 PRP85691.1 - 0.088 12.7 0.0 0.25 11.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 PRP85692.1 - 8.7e-52 175.9 4.7 8.7e-52 175.9 4.7 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain bPH_3 PF14470.6 PRP85692.1 - 0.0018 18.6 0.2 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 Bacterial PH domain Fib_alpha PF08702.10 PRP85692.1 - 0.019 15.2 6.7 0.053 13.7 6.7 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 PRP85692.1 - 0.03 14.4 1.8 0.03 14.4 1.8 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Lebercilin PF15619.6 PRP85692.1 - 0.17 11.5 15.2 0.26 10.9 7.2 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PI3K_P85_iSH2 PF16454.5 PRP85692.1 - 0.19 11.3 11.5 0.15 11.6 4.3 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cluap1 PF10234.9 PRP85692.1 - 0.2 11.0 10.4 0.34 10.3 10.4 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Spc7 PF08317.11 PRP85692.1 - 0.21 10.5 12.9 0.35 9.7 12.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 PRP85692.1 - 0.23 11.0 3.8 0.4 10.2 3.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 PRP85692.1 - 0.24 11.7 2.5 5.3 7.4 0.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ORF6C PF10552.9 PRP85692.1 - 0.35 11.0 6.3 2.4 8.3 0.6 2.5 2 0 0 2 2 2 0 ORF6C domain SlyX PF04102.12 PRP85692.1 - 1.5 9.5 4.1 7.3 7.3 0.3 3.0 2 1 1 3 3 3 0 SlyX Ly49 PF08391.10 PRP85692.1 - 5.8 7.3 11.4 0.76 10.1 3.8 2.8 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region THOC7 PF05615.13 PRP85692.1 - 6.7 7.0 10.7 22 5.3 10.6 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 UPF0242 PF06785.11 PRP85692.1 - 7.7 6.6 15.5 2.2 8.3 5.7 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Actin PF00022.19 PRP85693.1 - 1.3e-109 366.6 0.0 4.2e-109 364.9 0.0 1.8 1 1 0 1 1 1 1 Actin DHR-2 PF06920.13 PRP85693.1 - 6.4e-80 269.3 14.3 3.3e-42 144.8 1.1 2.7 3 0 0 3 3 3 2 Dock homology region 2 DOCK-C2 PF14429.6 PRP85693.1 - 4.3e-26 91.9 0.2 8.9e-25 87.6 0.2 2.5 1 1 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 PRP85693.1 - 1.9e-19 69.8 1.1 2.9e-18 66.0 0.3 2.3 2 0 0 2 2 2 1 DOCK N-terminus SH3_9 PF14604.6 PRP85693.1 - 2.5e-16 59.2 0.0 3.3e-09 36.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 PRP85693.1 - 3.1e-16 58.8 0.1 1.6e-06 27.7 0.0 3.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 PRP85693.1 - 1e-12 47.4 0.3 2.1e-05 24.1 0.0 2.8 2 0 0 2 2 2 2 SH3 domain SH3_10 PF17902.1 PRP85693.1 - 0.00068 19.7 0.1 0.14 12.2 0.0 2.9 2 0 0 2 2 2 1 SH3 domain Ank_3 PF13606.6 PRP85693.1 - 0.059 13.9 0.0 68 4.5 0.0 4.2 4 0 0 4 4 4 0 Ankyrin repeat UPF0220 PF05255.11 PRP85694.1 - 5.5e-28 97.6 0.6 9.7e-28 96.8 0.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Cyt_bd_oxida_I PF01654.17 PRP85694.1 - 0.0045 15.7 1.2 0.0059 15.3 0.2 1.6 2 0 0 2 2 2 1 Cytochrome bd terminal oxidase subunit I FA_desaturase PF00487.24 PRP85694.1 - 0.074 12.9 7.4 0.067 13.0 0.7 2.1 1 1 0 2 2 2 0 Fatty acid desaturase HMG_box PF00505.19 PRP85695.1 - 5e-15 55.7 6.2 1e-14 54.7 6.2 1.5 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PRP85695.1 - 9.1e-13 48.6 4.2 1.8e-12 47.7 4.2 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 PRP85695.1 - 0.031 14.2 0.5 0.044 13.8 0.5 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box 5 ETF_QO PF05187.13 PRP85696.1 - 2e-45 153.2 0.1 3.1e-45 152.6 0.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 PRP85696.1 - 7.8e-05 22.4 0.9 0.056 13.0 0.6 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 PRP85696.1 - 8.2e-05 22.0 0.0 0.0015 17.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 PRP85696.1 - 0.00035 19.8 0.0 0.0049 16.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP85696.1 - 0.0017 17.6 0.2 0.0028 16.9 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PRP85696.1 - 0.0053 16.1 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PRP85696.1 - 0.0098 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 PRP85696.1 - 0.012 15.9 0.1 0.035 14.3 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PRP85696.1 - 0.02 14.2 0.1 0.035 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PRP85696.1 - 0.032 14.2 0.1 0.07 13.1 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 PRP85696.1 - 0.057 12.7 0.5 0.092 12.0 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 PRP85696.1 - 0.087 13.4 1.0 0.21 12.2 1.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 PRP85696.1 - 0.096 12.9 0.8 0.21 11.8 0.8 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 PRP85696.1 - 0.16 11.0 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 PRP85696.1 - 0.17 10.7 0.1 0.4 9.5 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase BAH PF01426.18 PRP85698.1 - 2.5e-16 59.6 0.0 5.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 BAH domain HARE-HTH PF05066.13 PRP85698.1 - 5.8e-13 49.0 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Radical_SAM_C PF16199.5 PRP85700.1 - 4e-31 106.9 0.0 7.4e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 PRP85700.1 - 1.5e-17 64.5 0.9 6.2e-17 62.5 0.1 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 PRP85700.1 - 5e-11 42.9 0.0 9.2e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP85700.1 - 1.6e-06 28.1 0.0 3.8e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP85700.1 - 0.0035 17.8 0.0 0.0073 16.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP85700.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein La PF05383.17 PRP85701.1 - 6.3e-21 74.2 0.0 2.6e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 La domain Lipoxygenase PF00305.19 PRP85702.1 - 6.3e-21 74.5 0.0 8e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Lipoxygenase TRIC PF05197.13 PRP85704.1 - 1.1e-09 38.2 5.4 1.8e-09 37.4 5.4 1.3 1 0 0 1 1 1 1 TRIC channel DP PF08781.10 PRP85705.1 - 1.1e-29 103.1 0.9 3.8e-29 101.4 0.9 1.9 1 0 0 1 1 1 1 Transcription factor DP E2F_TDP PF02319.20 PRP85705.1 - 1.3e-18 66.8 1.0 2.6e-18 65.8 1.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain Fcf2 PF08698.11 PRP85705.1 - 0.0036 17.7 3.2 0.0036 17.7 3.2 2.7 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Methyltransf_2 PF00891.18 PRP85707.1 - 0.13 11.5 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Voltage_CLC PF00654.20 PRP85709.1 - 2.6e-10 40.1 9.9 1.1e-05 24.9 0.9 2.8 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 PRP85709.1 - 1.9e-05 25.0 0.0 4.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 CBS domain DUF3017 PF11222.8 PRP85709.1 - 0.1 12.9 4.1 0.13 12.6 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3017) PIRT PF15099.6 PRP85709.1 - 0.17 11.5 0.9 0.27 10.8 0.9 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF998 PF06197.13 PRP85709.1 - 0.18 11.4 7.1 3 7.4 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF998) TMEM238 PF15125.6 PRP85709.1 - 2 8.7 5.1 24 5.2 0.5 2.5 1 1 1 2 2 2 0 TMEM238 protein family p31comet PF06581.12 PRP85710.1 - 0.0014 17.9 0.1 0.54 9.4 0.0 2.6 2 2 1 3 3 3 2 Mad1 and Cdc20-bound-Mad2 binding Cas_Cas6 PF01881.16 PRP85710.1 - 0.045 14.3 0.5 0.14 12.7 0.0 2.0 2 1 1 3 3 3 0 CRISPR associated protein Cas6 B-block_TFIIIC PF04182.12 PRP85710.1 - 0.046 13.9 0.1 6.5 7.0 0.0 2.4 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC SAP130_C PF16014.5 PRP85710.1 - 0.065 12.3 0.4 1.3 8.0 0.1 2.1 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus Kelch_4 PF13418.6 PRP85710.1 - 0.16 12.0 0.0 19 5.3 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Ribosomal_L24e PF01246.20 PRP85710.1 - 0.41 10.9 1.8 7.5 6.9 0.1 2.6 3 0 0 3 3 3 0 Ribosomal protein L24e YiiD_C PF09500.10 PRP85714.1 - 0.093 12.6 0.0 6.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) Bul1_C PF04426.12 PRP85716.1 - 0.0059 16.0 1.3 0.0066 15.9 0.1 1.6 2 0 0 2 2 2 1 Bul1 C terminus WD40 PF00400.32 PRP85718.1 - 7.7e-36 121.5 33.1 4.2e-05 24.2 0.6 10.1 10 0 0 10 10 10 8 WD domain, G-beta repeat DUF769 PF05590.11 PRP85718.1 - 1.2e-06 28.2 1.0 9.4 5.6 0.0 6.3 1 1 7 8 8 8 1 Xylella fastidiosa protein of unknown function (DUF769) Tcp10_C PF07202.13 PRP85718.1 - 4.4e-06 26.8 0.0 0.82 9.6 0.0 3.9 1 1 2 3 3 3 3 T-complex protein 10 C-terminus Proteasome PF00227.26 PRP85718.1 - 0.00085 18.9 1.5 0.56 9.7 0.1 4.2 3 1 2 5 5 5 1 Proteasome subunit SnoaL_2 PF12680.7 PRP85718.1 - 0.0016 19.0 0.0 2.4 8.8 0.0 4.1 3 2 1 4 4 4 1 SnoaL-like domain Read-through PF16814.5 PRP85718.1 - 0.0024 17.7 2.3 25 4.6 0.0 5.1 2 2 3 6 6 6 0 Read-through domain Invasin_D3 PF09134.10 PRP85718.1 - 0.017 15.4 22.1 4.7 7.6 0.4 7.0 2 2 7 9 9 9 0 Invasin, domain 3 HARP PF07443.13 PRP85718.1 - 0.018 14.7 0.4 1.1 8.9 0.0 3.8 4 2 1 5 5 5 0 HepA-related protein (HARP) NusG_II PF07009.11 PRP85718.1 - 0.036 14.3 0.1 1.9 8.7 0.0 3.1 2 1 1 3 3 3 0 NusG domain II Abi_C PF14355.6 PRP85718.1 - 0.096 12.8 2.6 4.3 7.5 0.1 4.1 4 1 1 5 5 5 0 Abortive infection C-terminus Nup160 PF11715.8 PRP85718.1 - 1.1 7.8 16.4 6.1 5.4 0.1 5.6 3 3 3 7 7 7 0 Nucleoporin Nup120/160 Peptidase_C48 PF02902.19 PRP85720.1 - 9.8e-08 32.1 0.1 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain MBOAT PF03062.19 PRP85720.1 - 0.024 14.0 0.4 0.039 13.3 0.4 1.2 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family LupA PF18242.1 PRP85720.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain HEAT_EZ PF13513.6 PRP85721.1 - 9.6e-07 29.2 1.5 0.033 14.7 0.5 3.6 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 PRP85721.1 - 0.0059 17.0 0.1 1.6 9.1 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 PRP85721.1 - 0.011 16.0 4.5 0.12 12.7 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat IFRD PF05004.13 PRP85721.1 - 0.1 11.7 0.0 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) p450 PF00067.22 PRP85723.1 - 2.7e-86 290.2 0.0 3.3e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHASE9 PF17153.4 PRP85723.1 - 0.00042 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Periplasmic sensor domain, extracellular D123 PF07065.14 PRP85724.1 - 2.4e-11 43.3 3.6 5e-11 42.3 0.4 2.5 2 1 1 3 3 3 1 D123 R2K_2 PF18299.1 PRP85724.1 - 0.00022 21.1 0.1 0.00052 19.9 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 PRP85724.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 IMS PF00817.20 PRP85725.1 - 9.7e-42 142.5 0.3 2e-29 102.5 0.0 3.3 4 0 0 4 4 4 2 impB/mucB/samB family YqeY PF09424.10 PRP85725.1 - 1.3e-18 67.5 7.7 1.3e-18 67.5 7.7 3.5 4 0 0 4 4 4 1 Yqey-like protein IMS_C PF11799.8 PRP85725.1 - 1.9e-16 60.8 0.2 1.9e-15 57.6 0.0 2.7 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 PRP85725.1 - 1.3e-09 38.3 0.0 3.5e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 PRP85725.1 - 0.00057 20.1 0.0 0.0017 18.6 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 PRP85725.1 - 0.0006 20.1 0.0 0.0049 17.2 0.0 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 PRP85725.1 - 0.0043 17.3 0.0 0.014 15.6 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif PTCB-BRCT PF12738.7 PRP85725.1 - 0.0099 15.8 0.0 0.048 13.6 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain mCpol PF18182.1 PRP85725.1 - 0.02 15.2 0.0 0.066 13.6 0.0 1.9 1 0 0 1 1 1 0 minimal CRISPR polymerase domain BUD22 PF09073.10 PRP85725.1 - 0.15 11.4 41.7 1.2 8.4 15.5 2.7 2 0 0 2 2 2 0 BUD22 Glyco_hydro_18 PF00704.28 PRP85726.1 - 4.1e-14 53.0 6.0 1.2e-13 51.5 6.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Per1 PF04080.13 PRP85727.1 - 1.3e-38 133.3 17.3 3e-38 132.0 17.3 1.6 1 1 0 1 1 1 1 Per1-like family Methyltransf_31 PF13847.6 PRP85728.1 - 5.3e-08 32.8 0.0 7.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP85728.1 - 1.3e-07 32.1 0.0 2.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP85728.1 - 6e-07 30.1 0.0 1e-06 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP85728.1 - 2.1e-06 27.7 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 PRP85728.1 - 2.8e-05 23.7 0.0 0.00015 21.4 0.0 2.0 1 1 0 1 1 1 1 Histone methylation protein DOT1 Cons_hypoth95 PF03602.15 PRP85728.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 PRP85728.1 - 0.00099 18.6 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 PRP85728.1 - 0.0049 17.6 0.0 0.0081 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP85728.1 - 0.0053 16.1 0.0 0.032 13.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 PRP85728.1 - 0.0069 15.9 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 PRP85728.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PRP85728.1 - 0.032 14.0 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 PRP85728.1 - 0.035 13.7 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF2718 PF10918.8 PRP85728.1 - 0.12 12.9 0.0 0.29 11.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2718) CMAS PF02353.20 PRP85728.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 PRP85728.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain HSP70 PF00012.20 PRP85729.1 - 1.2e-218 727.2 0.1 1.2e-218 727.2 0.1 2.8 2 1 1 3 3 3 1 Hsp70 protein I_LWEQ PF01608.17 PRP85729.1 - 5.3e-19 69.0 1.0 5.3e-19 69.0 1.0 3.5 3 1 0 3 3 3 1 I/LWEQ domain MreB_Mbl PF06723.13 PRP85729.1 - 2.4e-14 52.9 0.1 6.4e-14 51.5 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein VHP PF02209.19 PRP85729.1 - 6.5e-12 45.3 3.0 2.2e-11 43.6 3.0 2.0 1 0 0 1 1 1 1 Villin headpiece domain Hydantoinase_A PF01968.18 PRP85729.1 - 0.016 14.5 0.4 0.041 13.1 0.4 1.7 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 PRP85729.1 - 0.087 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 StbA protein CTNNB1_binding PF08347.11 PRP85729.1 - 3.9 7.6 7.5 2.9 8.0 1.0 2.6 2 1 0 2 2 2 0 N-terminal CTNNB1 binding Prefoldin PF02996.17 PRP85730.1 - 4.9e-24 84.5 1.0 6.6e-24 84.1 0.5 1.4 1 1 0 1 1 1 1 Prefoldin subunit DUF3990 PF13151.6 PRP85730.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) Prefoldin_3 PF13758.6 PRP85730.1 - 0.027 14.5 0.1 0.051 13.6 0.1 1.6 1 1 0 1 1 1 0 Prefoldin subunit ApoO PF09769.9 PRP85730.1 - 0.064 13.2 1.5 11 6.0 0.1 3.0 2 1 1 3 3 3 0 Apolipoprotein O FAM195 PF14799.6 PRP85730.1 - 0.072 13.4 0.9 0.15 12.4 0.3 1.9 1 1 1 2 2 2 0 FAM195 family WXG100 PF06013.12 PRP85730.1 - 0.91 9.8 7.9 3.4 8.0 1.5 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG FAD_binding_4 PF01565.23 PRP85733.1 - 1.3e-12 47.6 0.0 2.2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4509 PF14970.6 PRP85734.1 - 6.3e-18 65.4 0.4 1.5e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4509) Pkinase PF00069.25 PRP85735.1 - 4.8e-73 245.8 0.0 6.1e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85735.1 - 9.5e-37 126.7 0.0 1.3e-36 126.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP85735.1 - 9.8e-21 74.2 0.1 2.4e-20 73.0 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP85735.1 - 7.9e-08 32.7 0.5 5.1e-07 30.1 0.5 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 PRP85735.1 - 1.2e-05 24.8 0.0 6.9e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 PRP85735.1 - 0.00023 21.8 0.2 0.00057 20.5 0.2 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 PRP85735.1 - 0.00025 20.8 0.1 0.68 9.5 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PRP85735.1 - 0.0019 18.1 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP85735.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_8 PF15409.6 PRP85735.1 - 0.0097 16.2 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PRP85735.1 - 0.05 14.0 0.1 1.3 9.4 0.1 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain Peptidase_M1 PF01433.20 PRP85736.1 - 6.7e-75 251.4 0.8 1.4e-74 250.3 0.8 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 PRP85736.1 - 5.3e-58 197.0 0.5 7.6e-58 196.5 0.5 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PRP85736.1 - 1.7e-41 142.4 0.2 2.9e-41 141.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 PRP85736.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative aminopeptidase BBS2_Mid PF14783.6 PRP85737.1 - 0.00014 21.9 0.0 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 PRP85737.1 - 0.0028 17.1 0.0 0.045 13.1 0.0 2.7 3 1 1 4 4 4 1 PTHB1 N-terminus TMF_DNA_bd PF12329.8 PRP85737.1 - 0.42 10.6 2.6 1.3 9.1 2.6 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PrmA PF06325.13 PRP85738.1 - 1.2e-07 31.5 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PRP85738.1 - 2e-06 27.5 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5_C PF17286.2 PRP85738.1 - 9e-06 25.7 0.1 1.3e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_31 PF13847.6 PRP85738.1 - 0.0028 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 PRP85738.1 - 0.0029 16.7 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 PRP85738.1 - 0.0098 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 PRP85738.1 - 0.024 15.3 0.0 0.048 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 PRP85738.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 PRP85738.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Dis3l2_C_term PF17877.1 PRP85738.1 - 0.13 12.6 0.2 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal PH PF00169.29 PRP85739.1 - 3.4e-09 37.2 5.4 6.5e-08 33.0 0.2 3.1 2 2 2 4 4 4 2 PH domain PH_11 PF15413.6 PRP85739.1 - 6.2e-05 23.4 2.6 0.0011 19.4 0.8 2.7 1 1 1 2 2 2 1 Pleckstrin homology domain PBD PF00786.28 PRP85739.1 - 0.0082 16.5 0.6 0.063 13.6 0.3 2.7 1 1 0 1 1 1 1 P21-Rho-binding domain PH_8 PF15409.6 PRP85739.1 - 0.026 14.8 0.4 12 6.2 0.0 3.4 3 1 1 4 4 4 0 Pleckstrin homology domain WH1 PF00568.23 PRP85739.1 - 0.028 14.3 0.1 0.21 11.5 0.1 2.3 2 1 1 3 3 3 0 WH1 domain DCP1 PF06058.13 PRP85739.1 - 0.034 14.1 0.2 0.46 10.4 0.0 2.4 2 0 0 2 2 2 0 Dcp1-like decapping family YcbB PF08664.10 PRP85739.1 - 0.052 13.6 1.1 0.28 11.2 0.0 2.5 3 0 0 3 3 3 0 YcbB domain DUF3572 PF12096.8 PRP85739.1 - 0.073 13.3 0.0 0.24 11.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3572) NFACT-R_1 PF05670.13 PRP85740.1 - 1.6e-32 112.4 0.0 3.6e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Sep15_SelM PF08806.11 PRP85740.1 - 5.2e-17 61.8 0.2 1.4e-16 60.4 0.0 1.8 2 0 0 2 2 2 1 Sep15/SelM redox domain COX15-CtaA PF02628.15 PRP85740.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein VIT1 PF01988.19 PRP85740.1 - 0.29 11.0 2.2 0.27 11.1 0.7 1.7 2 0 0 2 2 2 0 VIT family AAA_11 PF13086.6 PRP85740.1 - 0.85 9.4 6.7 1.3 8.7 6.7 1.3 1 0 0 1 1 1 0 AAA domain LRR_8 PF13855.6 PRP85741.1 - 1.2e-121 396.5 212.7 9.8e-09 34.9 4.4 29.5 23 6 6 30 30 30 27 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP85741.1 - 2.2e-110 368.0 0.1 1.1e-58 198.6 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PRP85741.1 - 3.7e-79 259.2 234.4 4.5e-05 23.7 4.6 38.3 24 10 20 45 45 43 31 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP85741.1 - 1.4e-74 250.8 0.0 6.3e-38 130.6 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain LRR_1 PF00560.33 PRP85741.1 - 9.6e-08 31.6 214.9 1.2 9.9 0.3 48.4 51 7 4 55 55 45 5 Leucine Rich Repeat Kdo PF06293.14 PRP85741.1 - 1.1e-06 28.2 0.3 0.058 12.7 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP85741.1 - 4.8e-06 25.6 0.0 0.088 11.6 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 PRP85741.1 - 2.1e-05 24.0 0.0 0.13 11.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like TMEM132D_C PF15706.5 PRP85741.1 - 6e-05 22.7 2.0 0.39 10.5 0.0 3.3 3 0 0 3 3 3 2 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Mid2 PF04478.12 PRP85741.1 - 0.0037 17.1 2.5 1.8 8.4 0.2 2.4 2 0 0 2 2 2 2 Mid2 like cell wall stress sensor DUF2627 PF11118.8 PRP85741.1 - 0.016 15.7 0.1 13 6.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) DUF3827 PF12877.7 PRP85741.1 - 0.019 13.4 4.1 1.5 7.1 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) MacB_PCD PF12704.7 PRP85741.1 - 0.02 15.2 4.1 1.9 8.8 0.3 2.8 2 0 0 2 2 2 0 MacB-like periplasmic core domain Reo_sigmaC PF04582.12 PRP85741.1 - 0.048 13.9 1.1 11 6.3 0.1 3.2 3 0 0 3 3 3 0 Reovirus sigma C capsid protein C-terminal domain Orf78 PF06024.12 PRP85741.1 - 0.054 13.8 0.0 9.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Orf78 (ac78) SKG6 PF08693.10 PRP85741.1 - 0.31 10.5 16.1 0.44 10.0 4.0 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 PRP85741.1 - 0.69 10.0 10.1 0.68 10.1 0.6 2.9 3 0 0 3 3 2 0 Insulin receptor trans-membrane segment PTP_tm PF18861.1 PRP85741.1 - 1.1 9.2 7.7 7.6 6.5 0.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2929 PF11151.8 PRP85741.1 - 1.3 9.3 9.3 8.6 6.7 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Pilin_N PF07790.11 PRP85741.1 - 5.7 7.9 8.6 15 6.6 0.9 2.7 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal LRR_8 PF13855.6 PRP85743.1 - 2e-115 376.6 203.6 3.6e-10 39.5 3.1 30.6 20 8 12 34 34 34 29 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP85743.1 - 5.4e-111 370.0 0.0 4.5e-55 186.7 0.0 3.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP85743.1 - 5.6e-75 252.1 0.0 1.4e-36 126.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain LRR_4 PF12799.7 PRP85743.1 - 2.3e-73 240.8 213.6 3.7e-06 27.2 1.5 36.3 27 8 11 41 41 38 24 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP85743.1 - 1e-12 46.7 192.7 0.88 10.4 0.1 47.8 52 5 1 53 53 41 3 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP85743.1 - 5.1e-09 36.3 3.1 0.00023 21.4 0.1 3.0 2 0 0 2 2 2 2 Leucine rich repeat N-terminal domain Pkinase_fungal PF17667.1 PRP85743.1 - 2e-06 26.8 0.0 0.049 12.4 0.0 2.3 2 0 0 2 2 2 2 Fungal protein kinase TMEM132D_C PF15706.5 PRP85743.1 - 1.2e-05 24.9 0.1 0.25 11.1 0.0 2.8 2 0 0 2 2 2 2 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Kinase-like PF14531.6 PRP85743.1 - 2.1e-05 24.0 0.1 0.18 11.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PRP85743.1 - 0.00013 21.3 0.2 0.32 10.3 0.1 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2627 PF11118.8 PRP85743.1 - 0.00097 19.7 0.1 3.2 8.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2627) LRR_6 PF13516.6 PRP85743.1 - 0.00098 19.0 164.9 1.3 9.2 0.4 40.4 47 0 0 47 47 43 2 Leucine Rich repeat TMEM154 PF15102.6 PRP85743.1 - 0.0023 17.9 0.1 2 8.3 0.0 2.6 2 0 0 2 2 2 2 TMEM154 protein family SKG6 PF08693.10 PRP85743.1 - 0.0098 15.3 16.1 0.13 11.7 3.8 2.4 2 0 0 2 2 2 2 Transmembrane alpha-helix domain MacB_PCD PF12704.7 PRP85743.1 - 0.016 15.5 3.2 3.6 7.9 0.2 2.8 2 0 0 2 2 2 0 MacB-like periplasmic core domain Mid2 PF04478.12 PRP85743.1 - 0.024 14.4 3.3 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Orf78 PF06024.12 PRP85743.1 - 0.028 14.7 0.0 9.7 6.6 0.0 2.7 2 0 0 2 2 2 0 Orf78 (ac78) DUF3827 PF12877.7 PRP85743.1 - 0.042 12.2 5.8 1.2 7.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) Insulin_TMD PF17870.1 PRP85743.1 - 0.05 13.7 2.6 9.9 6.3 0.2 2.9 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 PRP85743.1 - 0.28 12.1 1.9 30 5.6 0.1 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Alpha_GJ PF03229.13 PRP85743.1 - 0.32 11.5 7.3 9.5 6.8 1.5 2.9 2 0 0 2 2 2 0 Alphavirus glycoprotein J PTP_tm PF18861.1 PRP85743.1 - 0.43 10.5 8.9 4.8 7.1 1.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J LRR_9 PF14580.6 PRP85743.1 - 0.72 9.3 56.3 0.74 9.3 0.7 12.8 12 4 4 16 16 15 0 Leucine-rich repeat MARVEL PF01284.23 PRP85743.1 - 1.3 9.0 5.5 26 4.8 0.1 3.5 4 0 0 4 4 3 0 Membrane-associating domain Pilin_N PF07790.11 PRP85743.1 - 1.4 9.9 7.8 14 6.6 1.2 2.8 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF2929 PF11151.8 PRP85743.1 - 3.4 8.0 11.6 14 6.1 2.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) Y_phosphatase PF00102.27 PRP85744.1 - 4.5e-81 271.9 0.2 5.4e-81 271.6 0.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PRP85744.1 - 4.2e-05 23.4 0.1 9.6e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PRP85744.1 - 7.4e-05 22.8 0.9 0.00061 19.8 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PRP85744.1 - 0.032 14.4 0.3 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate Gastrin PF00918.17 PRP85744.1 - 0.038 15.0 0.0 1.8 9.5 0.0 2.4 2 0 0 2 2 2 0 Gastrin/cholecystokinin family SNN_linker PF09050.10 PRP85744.1 - 0.21 11.4 0.6 0.65 9.8 0.6 1.8 1 0 0 1 1 1 0 Stannin unstructured linker WD40 PF00400.32 PRP85745.1 - 4e-38 128.7 29.1 1.1e-06 29.2 0.9 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat BTB_2 PF02214.22 PRP85745.1 - 8e-18 64.6 2.4 2.2e-11 44.0 0.0 3.3 2 1 0 2 2 2 2 BTB/POZ domain BBS2_Mid PF14783.6 PRP85745.1 - 0.00073 19.5 0.0 0.62 10.1 0.0 3.5 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 PRP85745.1 - 0.0016 17.8 0.0 4.6 6.5 0.0 3.2 1 1 2 3 3 3 2 WD40-like domain Peptidase_C62 PF12380.8 PRP85745.1 - 0.015 14.4 2.7 15 4.6 0.1 3.5 1 1 1 3 3 3 0 Gill-associated viral 3C-like peptidase DUF812 PF05667.11 PRP85745.1 - 0.19 10.5 13.8 0.26 10.1 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PP2C_2 PF13672.6 PRP85745.1 - 7.5 6.1 7.9 6.2 6.4 2.1 3.4 2 1 1 3 3 3 0 Protein phosphatase 2C Pyr_redox_2 PF07992.14 PRP85746.1 - 3.4e-64 216.9 1.8 5.1e-64 216.3 1.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PRP85746.1 - 1.5e-35 121.7 2.8 3.8e-35 120.5 1.9 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PRP85746.1 - 5.6e-22 78.1 6.5 1e-20 74.1 1.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP85746.1 - 8.1e-20 71.3 0.7 1.4e-19 70.5 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PRP85746.1 - 6e-06 25.6 0.1 1.1e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 PRP85746.1 - 1e-05 25.1 0.4 2.8e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP85746.1 - 4.4e-05 22.4 3.2 0.2 10.3 0.6 3.0 2 1 0 3 3 3 2 HI0933-like protein NAD_binding_7 PF13241.6 PRP85746.1 - 0.00052 20.4 0.4 1.1 9.7 0.1 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 PRP85746.1 - 0.0006 19.2 3.4 0.18 11.1 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 PRP85746.1 - 0.00093 19.1 0.4 0.00093 19.1 0.4 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 PRP85746.1 - 0.0022 17.1 6.3 0.0045 16.1 1.2 2.5 2 1 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 PRP85746.1 - 0.0068 15.7 1.3 0.0086 15.3 0.1 1.7 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 PRP85746.1 - 0.0096 15.3 0.3 0.31 10.4 0.0 2.6 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3863 PF12979.7 PRP85746.1 - 0.015 14.2 0.1 0.043 12.7 0.1 1.7 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3863) FAD_binding_2 PF00890.24 PRP85746.1 - 0.024 13.7 3.5 0.028 13.5 2.2 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 PRP85746.1 - 0.062 13.5 0.8 0.2 11.9 0.8 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 PRP85746.1 - 0.074 12.3 0.5 1.4 8.1 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 PRP85746.1 - 0.14 12.1 1.5 0.68 9.9 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.24 PRP85746.1 - 0.53 9.8 12.1 0.24 10.9 0.6 3.2 3 1 1 4 4 4 0 FAD dependent oxidoreductase WD40 PF00400.32 PRP85747.1 - 6.2e-21 74.3 20.6 0.0018 19.1 0.2 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP85747.1 - 3.4e-06 27.3 10.0 0.015 15.6 0.1 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Proteasome PF00227.26 PRP85748.1 - 2e-54 184.0 0.0 2.5e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PRP85748.1 - 2.8e-14 52.4 0.1 6.4e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature adh_short PF00106.25 PRP85749.1 - 1.1e-22 80.4 0.0 7.9e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP85749.1 - 4.3e-15 55.9 0.0 6.9e-14 52.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.20 PRP85749.1 - 0.18 11.8 0.0 0.62 10.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GFA PF04828.14 PRP85750.1 - 2.1e-18 66.5 0.1 2.7e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LRR_4 PF12799.7 PRP85751.1 - 1.9e-06 28.1 1.3 4.2e-06 27.0 0.1 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) GAS PF13851.6 PRP85751.1 - 3.5e-05 23.3 27.4 3.5e-05 23.3 27.4 10.4 4 1 8 13 13 13 2 Growth-arrest specific micro-tubule binding LRR_6 PF13516.6 PRP85751.1 - 0.00043 20.1 0.9 14 6.0 0.2 3.8 3 0 0 3 3 3 3 Leucine Rich repeat LRR_8 PF13855.6 PRP85751.1 - 0.00082 19.1 0.2 0.0026 17.5 0.2 1.9 1 1 0 1 1 1 1 Leucine rich repeat Apo-CIII PF05778.12 PRP85751.1 - 0.025 14.2 1.8 0.074 12.7 0.3 2.7 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) ApoB100_C PF12491.8 PRP85751.1 - 1.4 8.9 10.4 0.15 12.0 0.2 3.9 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal Rap_GAP PF02145.15 PRP85752.1 - 5.8e-54 182.5 0.0 1.4e-53 181.2 0.0 1.7 2 0 0 2 2 2 1 Rap/ran-GAP WW PF00397.26 PRP85752.1 - 0.0041 17.2 0.0 0.0091 16.1 0.0 1.6 1 0 0 1 1 1 1 WW domain Borrelia_orfA PF02414.15 PRP85752.1 - 0.16 11.6 3.2 0.078 12.6 0.5 1.7 2 0 0 2 2 2 0 Borrelia ORF-A Vps8 PF12816.7 PRP85754.1 - 1.1e-43 149.0 4.0 4.7e-43 147.0 4.0 2.1 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 PRP85754.1 - 1.4e-12 47.7 3.5 1.2e-07 31.7 0.1 3.8 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 PRP85754.1 - 1.6e-05 24.7 0.9 3.7e-05 23.5 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP85754.1 - 0.00052 19.8 0.5 0.0014 18.4 0.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PRP85754.1 - 0.0086 16.4 6.9 0.026 14.8 6.9 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PRP85754.1 - 0.016 15.2 8.0 0.04 13.9 8.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 PRP85754.1 - 0.047 14.0 5.1 0.11 12.8 5.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PRP85754.1 - 0.15 12.0 5.1 0.35 10.8 5.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP85754.1 - 0.17 11.6 3.9 0.057 13.2 0.5 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 PRP85754.1 - 0.36 10.9 5.6 1.4 9.0 5.6 2.1 1 1 0 1 1 1 0 RING-type zinc-finger AHSP PF09236.10 PRP85754.1 - 0.78 10.2 3.2 0.57 10.7 0.4 2.2 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein Myb_DNA-binding PF00249.31 PRP85755.1 - 2.9e-27 94.6 0.6 1.9e-11 43.9 0.1 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PRP85755.1 - 2.6e-13 49.7 16.6 3.3e-08 33.3 0.6 4.7 3 1 1 4 4 4 3 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PRP85755.1 - 1.9e-11 44.0 9.7 1.7e-06 28.1 0.4 4.0 4 0 0 4 4 4 3 Myb-like DNA-binding domain GPS2_interact PF15784.5 PRP85755.1 - 2.8e-07 30.9 4.5 2.8e-07 30.9 4.5 4.5 3 0 0 3 3 3 1 G-protein pathway suppressor 2-interacting domain Pkinase_Tyr PF07714.17 PRP85757.1 - 1.8e-75 253.6 0.0 2.7e-75 253.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85757.1 - 4.1e-48 164.1 0.0 6e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP85757.1 - 1.8e-39 133.3 72.6 3.7e-09 36.2 0.1 13.1 5 3 9 16 16 16 14 Leucine rich repeat LRR_4 PF12799.7 PRP85757.1 - 7.1e-27 93.0 70.5 0.00017 21.9 0.7 15.1 5 3 13 20 20 20 16 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP85757.1 - 5.1e-08 32.4 63.9 4 8.4 0.1 20.9 22 4 0 22 22 22 2 Leucine Rich Repeat Kinase-like PF14531.6 PRP85757.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SKG6 PF08693.10 PRP85757.1 - 0.0017 17.7 2.9 0.0029 17.0 2.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_6 PF13516.6 PRP85757.1 - 0.051 13.7 50.7 10 6.5 0.1 16.2 20 0 0 20 20 20 0 Leucine Rich repeat Haspin_kinase PF12330.8 PRP85757.1 - 0.074 12.0 0.0 0.27 10.2 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain YajC PF02699.15 PRP85757.1 - 0.15 12.0 0.4 0.3 11.0 0.4 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit Ribosomal_L10 PF00466.20 PRP85758.1 - 4.3e-20 71.7 2.5 5.6e-20 71.3 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 PRP85758.1 - 2.1e-05 24.4 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 PRP85759.1 - 8.3e-22 77.6 6.9 1.2e-21 77.1 6.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein RL10P_insert PF17777.1 PRP85759.1 - 3.9e-11 42.8 0.1 6.4e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P VID27_N PF17748.1 PRP85759.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 VID27 N-terminal region HEM4 PF02602.15 PRP85760.1 - 8.5e-29 100.5 0.0 8.4e-26 90.7 0.0 2.1 1 1 1 2 2 2 2 Uroporphyrinogen-III synthase HemD C2 PF00168.30 PRP85761.1 - 4.6e-21 75.0 0.0 9.7e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain LRR_8 PF13855.6 PRP85761.1 - 1.6e-14 53.4 13.9 1.1e-06 28.3 1.5 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PRP85761.1 - 3.4e-11 43.2 18.7 0.00028 21.2 0.8 6.0 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP85761.1 - 0.00062 20.0 15.2 1.9 9.3 0.1 7.6 8 1 0 8 8 8 1 Leucine Rich Repeat Ank_2 PF12796.7 PRP85762.1 - 3.6e-36 123.6 1.8 3.1e-15 56.5 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP85762.1 - 1.7e-33 110.8 0.7 1.4e-05 25.1 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 PRP85762.1 - 1.1e-32 111.7 0.5 1.2e-09 38.2 0.1 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP85762.1 - 2.7e-32 110.7 0.2 1.7e-10 41.2 0.0 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP85762.1 - 3.5e-31 106.3 3.2 5.2e-05 23.5 0.0 6.4 6 0 0 6 6 6 6 Ankyrin repeat CE2_N PF17996.1 PRP85763.1 - 8.1e-11 41.9 0.0 3.8e-07 30.1 0.0 2.6 1 1 1 2 2 2 2 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 PRP85763.1 - 5.8e-08 33.3 0.3 2.4e-06 28.1 0.0 2.9 2 1 1 3 3 3 1 GDSL-like Lipase/Acylhydrolase family ATP-synt_S1 PF05827.12 PRP85763.1 - 0.02 14.7 0.2 0.058 13.2 0.0 1.8 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Lipase_GDSL PF00657.22 PRP85763.1 - 0.045 13.7 0.0 0.32 10.9 0.0 2.3 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Metallophos PF00149.28 PRP85765.1 - 3.3e-07 31.0 0.1 3.5e-06 27.7 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Y_Y_Y PF07495.13 PRP85766.1 - 0.11 12.5 1.0 7.3 6.6 0.0 3.7 4 0 0 4 4 4 0 Y_Y_Y domain PrgH PF09480.10 PRP85766.1 - 0.22 10.8 0.2 0.36 10.1 0.2 1.2 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) DUF745 PF05335.13 PRP85768.1 - 0.00062 19.5 6.2 0.00062 19.5 6.2 8.5 6 2 3 9 9 9 2 Protein of unknown function (DUF745) MCC-bdg_PDZ PF10506.9 PRP85768.1 - 0.0098 15.9 5.4 0.0098 15.9 5.4 8.8 9 1 1 10 10 10 1 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_1 PF00170.21 PRP85768.1 - 0.031 14.4 1.1 0.031 14.4 1.1 12.9 13 1 2 15 15 15 0 bZIP transcription factor EMC3_TMCO1 PF01956.16 PRP85768.1 - 0.73 9.6 0.0 0.73 9.6 0.0 5.5 4 1 3 7 7 7 0 Integral membrane protein EMC3/TMCO1-like L27_N PF09060.10 PRP85768.1 - 0.84 9.8 4.5 95 3.2 0.1 3.8 3 0 0 3 3 3 0 L27_N DUF3800 PF12686.7 PRP85768.1 - 6.8 7.4 12.9 1.2e+02 3.4 1.5 4.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3800) Deltameth_res PF16020.5 PRP85769.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Deltamethrin resistance Complex1_51K PF01512.17 PRP85771.1 - 4.3e-50 169.5 0.0 1e-49 168.3 0.0 1.7 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 PRP85771.1 - 1.5e-30 105.1 0.2 3.7e-30 103.8 0.2 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region RRM_1 PF00076.22 PRP85771.1 - 4.2e-30 103.4 0.0 1.9e-13 50.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLBB PF10531.9 PRP85771.1 - 2.6e-06 27.2 0.0 5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 SLBB domain Nup35_RRM PF05172.13 PRP85771.1 - 0.0091 15.9 0.0 0.11 12.4 0.0 2.3 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.12 PRP85771.1 - 0.1 12.9 0.1 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif 2 zf-C3HC4 PF00097.25 PRP85772.1 - 2.8e-07 30.3 10.5 5.2e-07 29.4 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP85772.1 - 8.4e-07 29.2 9.3 1.4e-06 28.5 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP85772.1 - 9.7e-07 28.5 8.7 1.7e-06 27.7 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP85772.1 - 2.2e-05 24.2 7.5 3.5e-05 23.6 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP85772.1 - 0.0001 22.5 9.7 0.00037 20.7 9.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP85772.1 - 0.0004 20.4 4.5 0.00092 19.2 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PRP85772.1 - 0.0016 18.3 7.8 0.0031 17.3 7.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP85772.1 - 0.0016 18.3 8.6 0.0029 17.5 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 PRP85772.1 - 0.037 14.0 4.5 0.061 13.3 4.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 PRP85772.1 - 0.71 10.1 8.8 1.4 9.1 8.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PRP85772.1 - 0.91 9.4 2.9 1.9 8.4 2.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 PRP85772.1 - 1.1 8.9 4.4 2.9 7.6 4.4 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_10 PF16685.5 PRP85772.1 - 2.4 8.3 4.7 5.6 7.2 4.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 PRP85772.1 - 2.7 7.8 7.2 6.2 6.7 7.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 PRP85772.1 - 4.3 7.2 8.3 8.3 6.3 8.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TRAM_LAG1_CLN8 PF03798.16 PRP85773.1 - 8.2e-13 48.5 22.7 1.5e-11 44.4 22.7 2.2 1 1 0 1 1 1 1 TLC domain DUF4229 PF14012.6 PRP85773.1 - 0.03 14.4 1.5 0.042 13.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Docking PF08990.11 PRP85773.1 - 0.1 12.2 4.4 0.16 11.6 4.4 1.3 1 0 0 1 1 1 0 Erythronolide synthase docking DUF2905 PF11146.8 PRP85773.1 - 6 7.1 10.8 2.6 8.3 5.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2905) Thioredoxin_4 PF13462.6 PRP85774.1 - 1.3e-09 38.4 0.0 5e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 PRP85774.1 - 0.0043 16.8 0.1 1.5 8.6 0.0 2.5 2 1 0 2 2 2 2 DSBA-like thioredoxin domain zf-RING_2 PF13639.6 PRP85775.1 - 1.6e-10 41.1 4.9 2.9e-10 40.3 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PRP85775.1 - 9e-08 31.7 4.7 1.7e-07 30.9 4.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PRP85775.1 - 9.2e-07 29.1 2.6 2.3e-06 27.8 2.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PRP85775.1 - 2.3e-06 27.4 6.3 4.1e-06 26.5 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP85775.1 - 1.5e-05 24.7 5.6 3.2e-05 23.7 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP85775.1 - 0.0016 18.5 5.0 0.0041 17.1 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP85775.1 - 0.0038 17.2 4.2 0.0072 16.3 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PRP85775.1 - 0.012 15.6 1.9 0.025 14.6 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PRP85775.1 - 0.028 14.0 4.6 0.058 13.0 4.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PRP85775.1 - 0.045 13.9 2.8 0.13 12.5 2.8 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain UIM PF02809.20 PRP85775.1 - 0.073 13.0 0.6 0.073 13.0 0.6 2.2 2 0 0 2 2 1 0 Ubiquitin interaction motif RINGv PF12906.7 PRP85775.1 - 0.28 11.4 3.2 0.78 9.9 3.2 1.8 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 PRP85775.1 - 0.41 10.8 3.5 1.1 9.5 3.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING SH2 PF00017.24 PRP85776.1 - 7e-10 38.9 0.1 1.1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 SH2 domain Epimerase PF01370.21 PRP85778.1 - 5.8e-48 163.5 0.0 1e-47 162.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF229 PF02995.17 PRP85778.1 - 1.3e-40 139.4 1.0 3.7e-40 138.0 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Pkinase_Tyr PF07714.17 PRP85778.1 - 3e-28 98.8 0.0 7.9e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85778.1 - 1.3e-21 77.2 0.0 3.2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GDP_Man_Dehyd PF16363.5 PRP85778.1 - 1.7e-11 44.1 0.0 5.4e-11 42.5 0.0 1.7 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Sulfatase PF00884.23 PRP85778.1 - 7.7e-05 22.2 0.5 0.0018 17.7 0.1 2.2 1 1 1 2 2 2 1 Sulfatase RmlD_sub_bind PF04321.17 PRP85778.1 - 0.00026 20.2 0.0 0.00053 19.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PRP85778.1 - 0.00044 19.5 0.4 0.0019 17.4 0.0 2.1 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Glucos_trans_II PF14264.6 PRP85778.1 - 0.006 16.0 7.2 0.011 15.1 7.2 1.4 1 0 0 1 1 1 1 Glucosyl transferase GtrII Metalloenzyme PF01676.18 PRP85778.1 - 0.0084 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 PRP85778.1 - 0.034 13.7 0.4 0.082 12.5 0.4 1.7 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DNA_ligase_aden PF01653.18 PRP85779.1 - 1.6e-83 280.4 0.5 1.1e-82 277.7 0.3 2.3 2 1 0 2 2 2 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 PRP85779.1 - 1e-26 92.6 0.8 3.1e-26 91.1 0.7 2.0 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 PRP85779.1 - 9.1e-16 57.7 0.1 2.8e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif BRCT PF00533.26 PRP85779.1 - 1.8e-11 44.3 0.1 7.7e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain HHH_5 PF14520.6 PRP85779.1 - 2.6e-06 28.0 0.3 0.12 13.0 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain PTCB-BRCT PF12738.7 PRP85779.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain 5_3_exonuc PF01367.20 PRP85779.1 - 0.036 14.7 0.0 0.32 11.6 0.0 2.4 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DNA_ligase_ZBD PF03119.16 PRP85779.1 - 0.04 13.9 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain ACT_7 PF13840.6 PRP85780.1 - 5e-33 112.7 0.2 2.5e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 PRP85780.1 - 2.4e-14 52.9 4.5 1.8e-07 30.8 0.3 3.1 3 0 0 3 3 3 2 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain ACT PF01842.25 PRP85780.1 - 8.8e-05 22.2 0.1 0.14 12.0 0.0 2.5 2 0 0 2 2 2 2 ACT domain Tic22 PF04278.12 PRP85780.1 - 0.049 13.0 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Tic22-like family PH PF00169.29 PRP85781.1 - 2.4e-11 44.1 0.1 5.8e-11 42.8 0.0 1.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 PRP85781.1 - 1.6e-05 25.3 0.2 9.7e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PRP85781.1 - 0.00017 21.6 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PRP85781.1 - 0.00077 19.7 0.0 0.0023 18.2 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 PRP85781.1 - 0.0065 16.9 2.2 0.08 13.4 0.7 2.8 2 2 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 PRP85781.1 - 0.012 15.4 0.6 0.018 14.9 0.1 1.6 2 0 0 2 2 2 0 Pleckstrin homology domain PH_16 PF17838.1 PRP85781.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 PH domain 4HBT PF03061.22 PRP85782.1 - 4.2e-08 33.4 0.0 6.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF1943 PF09172.11 PRP85783.1 - 0.032 13.5 4.5 0.043 13.0 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF3752 PF12572.8 PRP85783.1 - 0.49 10.9 32.9 0.094 13.2 21.9 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3752) Tau95_N PF17682.1 PRP85783.1 - 3.5 7.8 10.8 20 5.4 10.8 2.3 1 1 0 1 1 1 0 Tau95 Triple barrel domain AP3D1 PF06375.11 PRP85783.1 - 4 7.7 22.8 0.18 12.0 16.5 1.9 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 RB_A PF01858.17 PRP85784.1 - 3.9e-50 170.4 0.4 5.8e-48 163.4 0.0 3.3 3 0 0 3 3 3 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 PRP85784.1 - 1.3e-31 109.4 4.7 1.9e-30 105.6 3.1 3.2 3 0 0 3 3 3 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 PRP85784.1 - 1.2e-25 89.6 0.3 1.2e-25 89.6 0.3 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3452) eIF-5a PF01287.20 PRP85784.1 - 3.8e-24 84.6 0.1 7.3e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Cdc6_C PF09079.11 PRP85784.1 - 0.0094 15.9 0.1 0.16 12.0 0.0 3.0 3 0 0 3 3 3 1 CDC6, C terminal winged helix domain TFIIB PF00382.19 PRP85784.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIIB repeat ASD2 PF08687.11 PRP85784.1 - 0.27 10.7 1.1 1.1 8.8 0.3 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 bZIP_2 PF07716.15 PRP85785.1 - 2.1e-05 24.5 13.2 2.1e-05 24.5 13.2 2.6 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 PRP85785.1 - 0.00019 21.5 16.8 0.0005 20.1 16.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor TORC_C PF12886.7 PRP85785.1 - 0.066 13.8 0.5 0.66 10.6 0.2 2.5 2 1 0 2 2 2 0 Transducer of regulated CREB activity, C terminus DDE_Tnp_IS1 PF03400.13 PRP85785.1 - 0.2 12.0 0.6 0.54 10.6 0.2 1.7 2 0 0 2 2 2 0 IS1 transposase MAPEG PF01124.18 PRP85786.1 - 1.5e-09 37.8 1.0 2.7e-09 37.0 1.0 1.4 1 0 0 1 1 1 1 MAPEG family CENP-F_leu_zip PF10473.9 PRP85786.1 - 0.00075 19.5 12.4 0.00075 19.5 12.4 9.9 3 2 7 10 10 10 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 PRP85786.1 - 0.008 16.4 9.0 0.008 16.4 9.0 11.1 4 3 9 13 13 13 1 TATA element modulatory factor 1 TATA binding Trans_reg_C PF00486.28 PRP85786.1 - 0.63 10.2 5.3 46 4.2 0.1 4.4 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal Prenyltrans PF00432.21 PRP85787.1 - 1.2e-43 146.5 8.8 1.9e-11 43.5 0.1 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat dCache_1 PF02743.18 PRP85788.1 - 0.011 15.6 1.2 0.026 14.3 0.2 2.2 2 0 0 2 2 2 0 Cache domain DUF2935 PF11155.8 PRP85788.1 - 0.029 14.7 0.0 0.64 10.4 0.0 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DASH_Dam1 PF08653.10 PRP85788.1 - 0.043 13.6 2.5 22 5.0 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 LMP PF04778.12 PRP85788.1 - 0.047 13.6 0.3 0.047 13.6 0.3 3.1 4 1 0 4 4 4 0 LMP repeated region Proteasome PF00227.26 PRP85788.1 - 0.049 13.1 0.0 0.17 11.3 0.0 1.9 1 0 0 1 1 1 0 Proteasome subunit DUF4922 PF16269.5 PRP85788.1 - 0.097 12.4 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) HR1 PF02185.16 PRP85788.1 - 0.19 11.9 5.6 0.26 11.4 0.1 3.5 4 0 0 4 4 3 0 Hr1 repeat WXG100 PF06013.12 PRP85788.1 - 0.6 10.4 5.0 19 5.6 0.1 4.8 4 1 1 5 5 5 0 Proteins of 100 residues with WXG DUF745 PF05335.13 PRP85788.1 - 0.84 9.3 9.0 5.7 6.6 1.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 PRP85788.1 - 1.1 9.4 11.4 0.64 10.2 0.8 4.2 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family MIEAP PF16026.5 PRP85788.1 - 4.1 7.6 7.0 17 5.6 0.1 3.4 2 1 2 4 4 4 0 Mitochondria-eating protein CorA PF01544.18 PRP85788.1 - 5.3 6.3 12.1 7.2 5.8 6.1 2.3 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4200 PF13863.6 PRP85788.1 - 6.4 7.2 8.3 1.8 9.0 0.1 3.2 3 1 0 3 3 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 PRP85788.1 - 10 6.4 10.0 60 3.9 0.1 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Homeodomain PF00046.29 PRP85790.1 - 1e-11 44.5 0.4 2.1e-11 43.5 0.4 1.5 1 0 0 1 1 1 1 Homeodomain Helitron_like_N PF14214.6 PRP85790.1 - 0.11 12.8 0.7 0.16 12.1 0.7 1.2 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus TPT PF03151.16 PRP85791.1 - 2.1e-15 56.8 25.8 2.6e-15 56.5 25.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PRP85791.1 - 1.8e-07 31.4 36.9 5e-06 26.7 14.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family Form-deh_trans PF09163.11 PRP85791.1 - 0.33 10.7 3.2 7 6.5 0.0 4.3 5 0 0 5 5 5 0 Formate dehydrogenase N, transmembrane ORMDL PF04061.14 PRP85793.1 - 2.2e-40 137.6 6.7 2.5e-40 137.4 6.7 1.0 1 0 0 1 1 1 1 ORMDL family B-block_TFIIIC PF04182.12 PRP85795.1 - 2.4e-11 43.6 8.5 8.5e-11 41.9 0.2 5.0 7 0 0 7 7 7 1 B-block binding subunit of TFIIIC RNA_pol_Rpc34 PF05158.12 PRP85795.1 - 0.0003 20.3 12.4 0.28 10.5 0.0 5.0 4 1 0 4 4 4 2 RNA polymerase Rpc34 subunit MarR_2 PF12802.7 PRP85795.1 - 0.00037 20.3 0.6 67 3.5 0.0 5.9 6 0 0 6 6 6 0 MarR family CtsR_C PF17727.1 PRP85795.1 - 0.031 14.4 2.6 0.26 11.5 0.2 3.5 3 0 0 3 3 3 0 CtsR C-terminal dimerization domain HTH_20 PF12840.7 PRP85795.1 - 0.13 12.4 0.2 5.3 7.2 0.0 3.5 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 PRP85795.1 - 0.16 11.9 1.1 2.3 8.3 0.1 3.4 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain GAGA_bind PF06217.12 PRP85795.1 - 0.87 9.8 18.1 0.087 13.1 2.6 2.8 2 0 0 2 2 2 0 GAGA binding protein-like family DDHD PF02862.17 PRP85795.1 - 4.1 7.5 11.3 6.7 6.8 0.3 2.9 2 0 0 2 2 2 0 DDHD domain Myc_N PF01056.18 PRP85795.1 - 4.8 7.0 18.1 0.24 11.3 1.8 2.4 2 0 0 2 2 2 0 Myc amino-terminal region PLDc_2 PF13091.6 PRP85796.1 - 2.3e-18 66.4 0.3 2.4e-13 50.1 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 PRP85796.1 - 0.00039 20.5 2.7 0.17 12.1 0.4 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif KorB PF08535.10 PRP85797.1 - 0.16 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 KorB domain zf-MYND PF01753.18 PRP85798.1 - 3.6e-11 43.0 15.7 7e-11 42.0 15.7 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 PRP85798.1 - 0.29 11.5 8.3 0.58 10.5 8.3 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RCC1 PF00415.18 PRP85799.1 - 1.2e-50 169.9 19.5 1.1e-09 38.7 0.1 7.4 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP85799.1 - 9.4e-35 117.7 46.7 7.8e-11 41.5 0.0 7.9 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 PRP85799.1 - 0.00047 20.7 0.1 7.2 7.1 0.0 3.4 3 0 0 3 3 3 2 SUKH-3 immunity protein DUF4213 PF13938.6 PRP85799.1 - 0.018 15.3 1.1 1.5 9.1 0.0 3.0 3 1 0 3 3 3 0 Putative heavy-metal chelation Proteasome PF00227.26 PRP85800.1 - 2.3e-52 177.3 0.2 3e-52 176.9 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PRP85800.1 - 2.2e-15 56.0 0.1 3.7e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF608 PF04685.13 PRP85802.1 - 4.2e-133 444.0 5.7 5.5e-133 443.6 5.7 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 PRP85802.1 - 4e-74 249.9 0.4 5.5e-74 249.5 0.4 1.2 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term FaeA PF04703.12 PRP85802.1 - 0.029 14.7 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 FaeA-like protein DUF4516 PF14990.6 PRP85803.1 - 0.079 12.7 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) CLASP_N PF12348.8 PRP85804.1 - 6.5e-48 163.3 3.9 4.6e-32 111.4 0.1 4.4 4 0 0 4 4 4 4 CLASP N terminal UME PF08064.13 PRP85804.1 - 2.5e-07 30.5 0.0 0.018 14.9 0.0 3.9 3 0 0 3 3 3 2 UME (NUC010) domain Cnd1 PF12717.7 PRP85804.1 - 1.6e-06 28.2 10.7 0.031 14.3 0.2 5.9 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP85804.1 - 8e-06 25.7 11.2 0.044 14.0 0.0 9.4 12 0 0 12 12 12 1 HEAT repeat HEAT_EZ PF13513.6 PRP85804.1 - 0.00018 21.9 4.4 13 6.4 0.1 5.4 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 PRP85804.1 - 0.0002 21.5 0.8 4.4 7.5 0.1 3.8 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 PRP85804.1 - 0.0016 18.8 8.5 7.5 7.0 0.0 7.1 6 3 2 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.7 PRP85804.1 - 0.034 14.7 0.9 5.6 7.6 0.0 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 PRP85804.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.9 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis DUF4516 PF14990.6 PRP85804.1 - 0.3 10.8 2.3 0.71 9.6 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) Urb2 PF10441.9 PRP85805.1 - 4.1e-10 40.0 7.6 1.4e-09 38.2 0.0 4.3 4 1 0 5 5 5 1 Urb2/Npa2 family ssDNA_DBD PF18333.1 PRP85805.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 2.8 3 0 0 3 3 3 1 Non-canonical single-stranded DNA-binding domain Noggin PF05806.12 PRP85805.1 - 0.15 11.9 0.3 0.34 10.8 0.3 1.5 1 0 0 1 1 1 0 Noggin GCOM2 PF15328.6 PRP85807.1 - 3.4 8.0 6.0 5.3 7.4 6.0 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Tmemb_cc2 PF10267.9 PRP85807.1 - 6.4 5.8 5.7 8.5 5.4 5.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MMR_HSR1 PF01926.23 PRP85808.1 - 2.4e-23 82.4 0.2 9e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase YchF-GTPase_C PF06071.13 PRP85808.1 - 3.1e-21 75.3 0.0 7.5e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) FeoB_N PF02421.18 PRP85808.1 - 2.6e-07 30.3 0.1 1.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 PRP85808.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 PRP85808.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Dynamin family ERO1 PF04137.15 PRP85808.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) E1-E2_ATPase PF00122.20 PRP85808.1 - 3.4 7.1 4.7 1.3 8.5 1.3 2.1 1 1 0 1 1 1 0 E1-E2 ATPase Bax1-I PF01027.20 PRP85810.1 - 0.002 18.0 1.5 0.0025 17.7 1.5 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 AA_permease_2 PF13520.6 PRP85810.1 - 0.0037 16.2 4.3 0.0046 15.8 4.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2231 PF09990.9 PRP85810.1 - 0.064 13.7 2.6 0.12 12.9 2.6 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) PAP2_3 PF14378.6 PRP85810.1 - 0.33 10.6 6.7 0.73 9.5 6.7 1.5 1 1 0 1 1 1 0 PAP2 superfamily CLU PF13236.6 PRP85811.1 - 1.6e-56 191.6 0.0 3.7e-56 190.4 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria Pkinase PF00069.25 PRP85811.1 - 3.4e-23 82.3 0.0 7.9e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Peptidase_M16_C PF05193.21 PRP85811.1 - 1.3e-21 77.5 0.0 7.1e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PRP85811.1 - 6.4e-16 58.7 0.0 1.4e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Pkinase_Tyr PF07714.17 PRP85811.1 - 9.6e-14 51.3 0.0 1.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase eIF3_p135 PF12807.7 PRP85811.1 - 3.3e-06 27.3 0.2 1.4e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TOM20_plant PF06552.12 PRP85811.1 - 0.042 13.6 5.0 9 6.0 0.0 3.9 4 0 0 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 TruB_N PF01509.18 PRP85811.1 - 0.094 13.1 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 TruB family pseudouridylate synthase (N terminal domain) BCD PF15461.6 PRP85812.1 - 2.9e-35 122.1 12.8 9.8e-35 120.3 12.8 1.9 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase Pkinase_Tyr PF07714.17 PRP85812.1 - 5.5e-14 52.1 0.4 3.1e-10 39.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase GPS PF01825.21 PRP85812.1 - 7.3e-10 39.2 5.2 1.9e-09 37.9 1.3 3.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP85812.1 - 3.5e-07 29.9 0.3 0.00039 19.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain ABC_ATPase PF09818.9 PRP85813.1 - 3.7e-167 556.7 0.0 4.8e-167 556.3 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 PRP85813.1 - 0.002 18.7 2.6 0.01 16.3 2.6 2.1 1 1 0 1 1 1 1 AAA domain DUF4228 PF14009.6 PRP85813.1 - 0.83 10.0 3.0 1.4 9.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) Ank_5 PF13857.6 PRP85814.1 - 6.9e-23 80.4 2.2 9.6e-10 38.5 0.3 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP85814.1 - 3.6e-20 72.3 0.5 5e-12 46.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP85814.1 - 1.3e-17 62.0 2.0 1.1e-06 28.5 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 PRP85814.1 - 5.6e-16 58.2 0.2 3.2e-07 30.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 PRP85814.1 - 1.2e-14 54.4 2.7 1.7e-06 28.5 0.0 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.17 PRP85814.1 - 0.062 13.6 0.0 4.4 7.6 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S6 His_Phos_1 PF00300.22 PRP85815.1 - 2.5e-35 121.9 0.0 3.8e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pro_isomerase PF00160.21 PRP85815.1 - 7.4e-09 36.1 0.0 1.5e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Stm1_N PF09598.10 PRP85815.1 - 0.47 11.3 2.8 1.1 10.1 2.8 1.6 1 0 0 1 1 1 0 Stm1 Acetyltransf_1 PF00583.25 PRP85816.1 - 3.7e-14 53.0 0.0 6.3e-14 52.2 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP85816.1 - 1.5e-10 41.1 0.2 2.1e-10 40.6 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP85816.1 - 4.3e-09 36.7 0.1 6.8e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP85816.1 - 7.2e-05 23.5 0.0 9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP85816.1 - 0.00034 20.7 0.0 0.00045 20.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 PRP85816.1 - 0.0078 14.8 0.0 0.012 14.2 0.0 1.3 1 0 0 1 1 1 1 Arginine N-succinyltransferase beta subunit Sec63 PF02889.16 PRP85816.1 - 0.035 13.3 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Sec63 Brl domain Acetyltransf_4 PF13420.7 PRP85816.1 - 0.037 14.2 0.1 3.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP85816.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase POX PF07526.11 PRP85817.1 - 2 9.0 12.1 0.48 11.0 7.9 2.1 1 1 1 2 2 2 0 Associated with HOX RmlD_sub_bind PF04321.17 PRP85818.1 - 7.3e-14 51.5 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 PRP85818.1 - 1.6e-13 50.7 0.0 4.6e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP85818.1 - 4.5e-11 43.0 0.2 1.2e-10 41.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PRP85818.1 - 5.2e-08 32.7 0.3 1.1e-07 31.6 0.3 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 PRP85818.1 - 1.4e-07 30.8 0.0 2.6e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PRP85818.1 - 1.4e-06 28.0 0.0 3.4e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 PRP85818.1 - 0.0002 20.9 0.1 0.00096 18.7 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.18 PRP85818.1 - 0.0027 18.0 0.0 0.01 16.1 0.0 2.0 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 PRP85818.1 - 0.0084 16.4 0.1 0.019 15.2 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 PRP85818.1 - 0.012 14.8 0.8 0.2 10.8 0.1 2.7 2 1 1 3 3 3 0 Male sterility protein KR PF08659.10 PRP85818.1 - 0.1 12.5 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 PRP85818.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NUC153 PF08159.12 PRP85820.1 - 9.3e-08 31.8 1.5 9.3e-08 31.8 1.5 2.8 2 0 0 2 2 2 1 NUC153 domain Aminotran_5 PF00266.19 PRP85821.1 - 8.8e-52 176.3 0.0 1.1e-51 176.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V CLU PF13236.6 PRP85823.1 - 4.3e-60 203.3 0.0 9.2e-60 202.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria LRR_4 PF12799.7 PRP85823.1 - 1.9e-19 69.4 28.9 0.016 15.7 0.2 10.9 8 2 4 12 12 12 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP85823.1 - 6.2e-08 32.1 32.2 0.17 12.0 0.0 12.7 14 0 0 14 14 14 3 Leucine Rich repeat LRR_8 PF13855.6 PRP85823.1 - 1.1e-05 25.1 24.7 0.00078 19.2 1.3 6.3 5 1 1 6 6 6 3 Leucine rich repeat eIF3_p135 PF12807.7 PRP85823.1 - 0.0005 20.2 0.2 0.0016 18.5 0.2 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 DUF1699 PF08004.11 PRP85823.1 - 1.1 9.0 7.6 26 4.5 0.0 5.5 5 3 2 7 7 7 0 Protein of unknown function (DUF1699) LRR_1 PF00560.33 PRP85823.1 - 3.1 8.7 33.2 49 5.0 0.2 11.5 11 2 2 13 13 13 0 Leucine Rich Repeat Flocculin_t3 PF13928.6 PRP85825.1 - 0.012 16.1 1.5 0.035 14.6 1.5 1.8 1 0 0 1 1 1 0 Flocculin type 3 repeat C1ORF64 PF15547.6 PRP85825.1 - 0.058 13.9 0.2 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein MFS_1 PF07690.16 PRP85826.1 - 4.8e-18 65.2 36.5 4.8e-18 65.2 36.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily KorB PF08535.10 PRP85828.1 - 8.4e-25 86.6 0.0 43 4.2 0.0 16.2 17 0 0 17 17 17 13 KorB domain DcrB PF08786.11 PRP85828.1 - 1.6e-08 34.7 0.3 1.7e+02 2.3 0.0 12.8 17 0 0 17 17 17 0 DcrB Sm_multidrug_ex PF06695.11 PRP85828.1 - 2.4e-06 28.2 49.2 38 4.9 0.1 16.4 18 0 0 18 18 18 1 Putative small multi-drug export protein Piezo_RRas_bdg PF12166.8 PRP85832.1 - 2.9e-53 181.7 0.1 3.4e-53 181.5 0.1 1.0 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Hemerythrin PF01814.23 PRP85833.1 - 2e-12 47.9 8.6 3.8e-12 46.9 8.6 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4142 PF13628.6 PRP85833.1 - 0.44 10.8 2.7 0.5 10.6 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) X8 PF07983.13 PRP85834.1 - 2.4e-28 98.6 27.9 3e-09 37.4 4.2 4.0 3 0 0 3 3 3 3 X8 domain CBM_5_12_2 PF14600.6 PRP85834.1 - 3.1e-07 30.2 12.1 0.12 12.3 0.4 3.7 3 0 0 3 3 3 3 Cellulose-binding domain Cellulase PF00150.18 PRP85834.1 - 4.3e-07 29.6 0.0 8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GlgS PF08971.11 PRP85834.1 - 1.9e-05 24.6 1.2 4.4 7.4 0.0 3.4 3 0 0 3 3 3 3 Glycogen synthesis protein TssC PF17541.2 PRP85834.1 - 0.0053 15.6 0.1 11 4.8 0.0 3.1 3 0 0 3 3 3 2 Type VI secretion system, TssC, VipB BCDHK_Adom3 PF10436.9 PRP85835.1 - 4.8e-45 153.3 0.2 6.6e-45 152.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 PRP85835.1 - 7.9e-11 42.5 0.0 1.6e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PRP85835.1 - 7.5e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1580 PF07618.11 PRP85835.1 - 0.052 13.2 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Laminin_G_3 PF13385.6 PRP85836.1 - 6.1e-38 130.4 8.6 9.9e-21 74.5 0.2 3.1 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily zf-C2HC_2 PF13913.6 PRP85836.1 - 1e-28 98.6 27.0 3.8e-09 36.2 0.2 6.0 6 0 0 6 6 6 4 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 PRP85836.1 - 2.1e-06 27.5 2.0 2.5 8.0 0.0 4.9 4 0 0 4 4 4 2 Rad50 zinc hook motif Toxin_R_bind_N PF07953.12 PRP85836.1 - 0.00053 19.8 0.5 0.9 9.2 0.2 2.5 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding Laminin_G_2 PF02210.24 PRP85836.1 - 0.052 14.1 0.0 0.45 11.1 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain PyrI_C PF02748.15 PRP85836.1 - 0.056 13.4 0.6 18 5.4 0.0 4.1 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF4982 PF16355.5 PRP85836.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) HypA PF01155.19 PRP85836.1 - 0.45 10.6 17.0 0.43 10.6 1.3 5.2 4 1 1 5 5 5 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FliC PF12445.8 PRP85836.1 - 1.7 9.0 5.2 8.8 6.7 4.9 2.4 2 0 0 2 2 1 0 Flagellin protein zf_C2H2_10 PF18414.1 PRP85836.1 - 1.7 8.2 12.1 3 7.4 0.0 3.8 4 0 0 4 4 3 0 C2H2 type zinc-finger zf-C2H2_jaz PF12171.8 PRP85836.1 - 1.9 8.9 4.0 33 4.9 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF3039 PF11238.8 PRP85836.1 - 2.2 8.1 7.9 8.1 6.3 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) zf-C2H2_4 PF13894.6 PRP85836.1 - 3.3 8.8 35.5 0.16 12.9 0.4 6.8 6 1 1 7 7 6 0 C2H2-type zinc finger ADK_lid PF05191.14 PRP85836.1 - 5.3 7.1 18.9 15 5.7 0.1 5.1 4 1 0 4 4 4 0 Adenylate kinase, active site lid YhfH PF14149.6 PRP85836.1 - 7.5 6.6 9.1 28 4.8 0.1 4.4 4 0 0 4 4 4 0 YhfH-like protein Carb_bind PF10645.9 PRP85836.1 - 7.6 6.9 30.0 0.37 11.0 4.4 3.9 2 1 1 3 3 3 0 Carbohydrate binding DUF3564 PF12087.8 PRP85837.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3564) MMR_HSR1 PF01926.23 PRP85838.1 - 1.2e-14 54.3 0.0 1.4e-12 47.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP85838.1 - 3.7e-07 29.8 0.1 0.0022 17.5 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP85838.1 - 5.9e-06 26.3 0.1 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PRP85838.1 - 0.0003 20.9 2.1 0.0013 18.8 0.0 3.2 3 1 0 3 3 3 1 Dynamin family Roc PF08477.13 PRP85838.1 - 0.12 12.7 2.2 0.52 10.5 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF2076 PF09849.9 PRP85839.1 - 2.7 7.9 22.1 3.6 7.6 22.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Beta-prism_lec PF16458.5 PRP85840.1 - 0.055 13.4 0.1 0.07 13.1 0.1 1.2 1 0 0 1 1 1 0 Beta-prism lectin Peptidase_M28 PF04389.17 PRP85841.1 - 1.6e-29 103.0 0.0 3e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 PRP85841.1 - 7.7e-19 68.0 0.0 1.7e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 PRP85841.1 - 3.6e-12 46.2 0.1 1.3e-11 44.3 0.0 2.0 3 0 0 3 3 3 1 PA domain Nicastrin PF05450.15 PRP85841.1 - 0.00023 20.7 0.3 0.00099 18.6 0.0 2.0 2 0 0 2 2 2 1 Nicastrin Peptidase_M20 PF01546.28 PRP85841.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 EcKinase PF02958.20 PRP85844.1 - 1.1e-11 44.6 0.0 7.1e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase APH PF01636.23 PRP85844.1 - 4.5e-07 30.0 0.0 6.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 PRP85844.1 - 0.0039 16.1 0.0 0.0071 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 PRP85844.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3450 PF11932.8 PRP85845.1 - 0.00015 21.1 6.8 0.00022 20.6 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF812 PF05667.11 PRP85845.1 - 0.0011 18.0 3.1 0.0013 17.7 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) SURF6 PF04935.12 PRP85845.1 - 0.0031 17.3 3.9 0.0048 16.7 3.9 1.3 1 0 0 1 1 1 1 Surfeit locus protein 6 Med21 PF11221.8 PRP85845.1 - 0.0042 17.3 5.2 0.0042 17.3 5.2 1.7 2 0 0 2 2 2 1 Subunit 21 of Mediator complex SGT1 PF07093.11 PRP85845.1 - 0.013 14.0 2.6 0.02 13.4 2.5 1.3 1 1 0 1 1 1 0 SGT1 protein DUF445 PF04286.12 PRP85845.1 - 0.047 13.5 1.5 0.056 13.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) CHD5 PF04420.14 PRP85845.1 - 0.056 13.3 2.1 0.079 12.8 2.1 1.3 1 0 0 1 1 1 0 CHD5-like protein Fez1 PF06818.15 PRP85845.1 - 0.12 12.8 9.0 0.17 12.3 9.0 1.1 1 0 0 1 1 1 0 Fez1 Exonuc_VII_L PF02601.15 PRP85845.1 - 0.13 11.8 2.1 0.15 11.6 2.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 PRP85845.1 - 0.13 10.8 4.3 0.17 10.5 4.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Het-C PF07217.11 PRP85845.1 - 0.19 10.2 4.0 0.25 9.8 4.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C PA26 PF04636.13 PRP85845.1 - 0.23 10.4 3.5 0.29 10.0 3.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PFEMP PF03011.15 PRP85845.1 - 0.3 11.7 4.4 0.42 11.3 4.4 1.2 1 0 0 1 1 1 0 PFEMP DBL domain Fungal_TACC PF12709.7 PRP85845.1 - 0.43 11.0 7.2 0.27 11.7 4.0 2.1 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Cauli_AT PF03233.13 PRP85845.1 - 1.9 8.4 7.7 2.9 7.8 4.2 2.0 1 1 1 2 2 2 0 Aphid transmission protein Ost5 PF05251.12 PRP85847.1 - 1.5e-22 79.6 8.0 1.7e-22 79.5 8.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DUF2053 PF09767.9 PRP85847.1 - 0.0031 17.7 1.0 0.0037 17.4 1.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) zf-MYND PF01753.18 PRP85848.1 - 9.4e-05 22.4 23.0 0.00016 21.7 23.0 1.4 1 0 0 1 1 1 1 MYND finger Phage_DNA_bind PF02303.17 PRP85848.1 - 0.077 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-destabilising protein Homeodomain PF00046.29 PRP85850.1 - 1.9e-15 56.4 1.4 5.4e-15 55.0 1.4 1.7 1 0 0 1 1 1 1 Homeodomain THUMP PF02926.17 PRP85850.1 - 1.8e-11 44.3 0.5 1.8e-11 44.3 0.5 2.9 3 0 0 3 3 3 1 THUMP domain Homeobox_KN PF05920.11 PRP85850.1 - 0.00042 20.2 1.8 0.00059 19.7 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain P5-ATPase PF12409.8 PRP85850.1 - 2.4 8.3 6.7 0.86 9.7 3.3 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter MBOAT PF03062.19 PRP85851.1 - 1.3e-39 136.6 24.5 2.5e-39 135.6 24.5 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family OPT PF03169.15 PRP85852.1 - 8.5e-163 543.3 58.5 9.8e-163 543.1 58.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cytochrom_B558a PF05038.13 PRP85852.1 - 1.4 8.5 5.7 0.42 10.2 0.3 2.7 3 0 0 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit Ank_2 PF12796.7 PRP85853.1 - 3.9e-30 104.3 0.0 2.1e-08 34.7 0.0 4.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP85853.1 - 3.8e-22 78.3 0.0 5.2e-05 23.7 0.0 5.4 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP85853.1 - 1e-18 67.1 0.0 0.13 12.6 0.0 7.9 2 2 6 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP85853.1 - 4e-14 51.3 0.1 1.2 9.9 0.0 7.6 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 PRP85853.1 - 5.8e-12 45.5 0.9 0.78 10.3 0.0 7.8 6 2 2 8 8 8 3 Ankyrin repeat YlzJ PF14035.6 PRP85853.1 - 9.5e-05 22.5 0.1 33 4.8 0.0 5.9 6 1 1 7 7 7 0 YlzJ-like protein VWA_3_C PF18571.1 PRP85853.1 - 0.086 12.7 0.0 1.1e+02 2.8 0.0 4.2 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain SLATT_5 PF18160.1 PRP85854.1 - 0.017 14.5 0.2 0.017 14.5 0.2 2.1 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 ABC2_membrane_5 PF13346.6 PRP85854.1 - 0.17 11.5 4.1 0.061 12.9 1.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein VPR PF00522.18 PRP85854.1 - 0.23 11.5 1.9 0.72 9.9 1.9 1.9 1 0 0 1 1 1 0 VPR/VPX protein Ion_trans_2 PF07885.16 PRP85854.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.3 2 1 1 3 3 3 0 Ion channel SK_channel PF03530.14 PRP85854.1 - 0.31 11.0 7.6 0.079 12.9 1.4 2.7 3 0 0 3 3 3 0 Calcium-activated SK potassium channel Methyltransf_16 PF10294.9 PRP85855.1 - 1.2e-17 64.2 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 PRP85855.1 - 2.3e-07 31.4 0.0 5.5e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP85855.1 - 3.1e-05 23.9 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP85855.1 - 9.2e-05 23.0 0.0 0.00025 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP85855.1 - 0.00014 22.6 0.0 0.00027 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP85855.1 - 0.00033 20.1 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PRP85855.1 - 0.0061 16.1 0.0 0.029 13.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PRP85855.1 - 0.0068 15.8 0.0 0.0092 15.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.15 PRP85855.1 - 0.0092 15.3 0.0 0.021 14.2 0.0 1.5 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 PRP85855.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 PRP85855.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Cons_hypoth95 PF03602.15 PRP85855.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Myb_Cef PF11831.8 PRP85857.1 - 5.6e-44 150.5 7.2 5.6e-44 150.5 7.2 4.6 5 0 0 5 5 5 2 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 PRP85857.1 - 1.3e-22 79.7 7.3 7.2e-12 45.3 1.8 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP85857.1 - 2e-19 69.5 5.3 6.9e-13 48.6 4.9 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Aft1_HRA PF11786.8 PRP85857.1 - 0.47 10.8 6.9 0.037 14.4 1.5 1.9 2 0 0 2 2 2 0 Aft1 HRA domain Rap1_C PF11626.8 PRP85857.1 - 4.3 7.5 8.4 0.16 12.1 0.8 2.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain A_deaminase PF00962.22 PRP85858.1 - 4.3e-22 78.9 0.0 2.3e-21 76.5 0.0 2.0 2 1 0 2 2 2 1 Adenosine/AMP deaminase EF-hand_13 PF17958.1 PRP85858.1 - 0.13 12.1 0.2 43 4.0 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain A_deaminase_N PF08451.11 PRP85858.1 - 0.18 12.1 0.6 0.87 9.9 0.6 2.2 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Sortilin-Vps10 PF15902.5 PRP85861.1 - 7.6e-78 262.3 4.5 1e-77 261.8 4.5 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PRP85861.1 - 4.7e-25 88.9 2.7 6.8e-25 88.4 2.7 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 PRP85861.1 - 8.5e-06 25.0 34.7 0.64 10.3 0.2 8.5 8 0 0 8 8 8 3 BNR/Asp-box repeat BNR_6 PF15899.5 PRP85861.1 - 0.0069 16.3 8.3 8.5 6.8 0.1 5.5 6 0 0 6 6 6 2 BNR-Asp box repeat DUF4577 PF15145.6 PRP85861.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) CECR6_TMEM121 PF14997.6 PRP85861.1 - 0.16 11.8 0.1 0.16 11.8 0.1 1.5 2 0 0 2 2 2 0 CECR6/TMEM121 family OppC_N PF12911.7 PRP85861.1 - 1.3 9.1 3.3 8.7 6.4 0.6 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ADAM17_MPD PF16698.5 PRP85861.1 - 1.5 9.2 10.0 0.4 11.1 6.6 1.8 2 0 0 2 2 2 0 Membrane-proximal domain, switch, for ADAM17 Aminotran_1_2 PF00155.21 PRP85862.1 - 7.5e-68 229.3 0.0 8.9e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 PRP85862.1 - 0.00013 20.7 0.0 0.00022 20.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 PRP85862.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 PRP85862.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 PRP85862.1 - 0.0016 17.1 0.0 0.0031 16.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 PRP85862.1 - 0.0026 16.8 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V XYPPX PF02162.17 PRP85863.1 - 0.00016 21.3 71.7 0.00039 20.1 21.6 9.2 7 2 1 8 8 8 3 XYPPX repeat (two copies) Dehydrin PF00257.19 PRP85863.1 - 0.0069 17.0 3.3 0.012 16.1 3.3 1.3 1 0 0 1 1 1 1 Dehydrin SR-25 PF10500.9 PRP85863.1 - 0.012 15.2 6.7 0.017 14.7 6.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Comm PF15957.5 PRP85863.1 - 0.049 14.0 0.1 0.077 13.3 0.1 1.3 1 0 0 1 1 1 0 Commissureless Kelch_5 PF13854.6 PRP85864.1 - 1.2e-21 76.3 7.0 9.9e-05 22.2 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 PRP85864.1 - 4.1e-18 65.2 27.0 1.7e-05 24.9 0.1 7.3 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.6 PRP85864.1 - 2.6e-17 62.6 21.0 0.00013 21.9 0.2 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP85864.1 - 1.8e-14 53.4 16.1 0.016 15.5 0.2 6.6 5 1 1 6 6 6 5 Kelch motif WSC PF01822.19 PRP85864.1 - 3.9e-11 43.0 2.1 7.2e-11 42.1 2.1 1.4 1 0 0 1 1 1 1 WSC domain Kelch_2 PF07646.15 PRP85864.1 - 1.1e-10 41.0 14.3 0.0089 16.0 0.0 7.2 6 1 0 6 6 6 3 Kelch motif F-box-like PF12937.7 PRP85864.1 - 4.5e-09 36.1 0.1 1.6e-08 34.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like Kelch_1 PF01344.25 PRP85864.1 - 2.8e-08 33.2 12.4 0.017 14.7 0.0 6.3 6 1 0 6 6 6 3 Kelch motif F-box PF00646.33 PRP85864.1 - 3.8e-08 33.0 0.2 1.3e-07 31.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain Tmemb_185A PF10269.9 PRP85864.1 - 9.8e-05 22.1 23.8 0.0012 18.6 21.6 2.4 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein Rad1 PF02144.16 PRP85865.1 - 2e-62 210.8 1.3 2.8e-62 210.3 1.3 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ependymin PF00811.18 PRP85866.1 - 0.0057 16.9 0.3 0.96 9.7 0.1 2.3 2 0 0 2 2 2 2 Ependymin ubiquitin PF00240.23 PRP85867.1 - 9.4e-137 445.0 23.0 9.5e-34 115.0 0.9 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 PRP85867.1 - 1.9e-63 210.2 24.0 1.9e-15 56.4 1.0 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP85867.1 - 4.7e-24 84.7 12.3 0.00016 22.0 0.2 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 PRP85867.1 - 2e-16 59.7 5.8 0.017 15.0 0.1 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP85867.1 - 2.6e-15 56.5 4.5 0.054 13.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PRP85867.1 - 3.3e-15 56.5 1.6 0.085 13.4 0.0 4.1 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP85867.1 - 1.7e-14 54.0 10.7 0.026 14.9 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 PRP85867.1 - 1.4e-10 41.2 0.4 0.84 9.5 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 PRP85867.1 - 1.8e-07 31.1 25.7 11 6.2 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain DUF3861 PF12977.7 PRP85867.1 - 7.9e-07 29.2 3.9 6.9 6.9 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 PRP85867.1 - 8.1e-06 26.1 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 PRP85867.1 - 1.1e-05 24.9 0.8 2.6 7.3 0.0 3.2 3 0 0 3 3 3 3 RNA methyltransferase TmoB PF06234.12 PRP85867.1 - 1.7e-05 24.8 0.0 32 4.7 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) DUF493 PF04359.14 PRP85867.1 - 3.3e-05 24.4 0.1 44 4.8 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Big_7 PF17957.1 PRP85867.1 - 8.7e-05 23.2 0.1 63 4.4 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain Big_3_3 PF13750.6 PRP85867.1 - 9.1e-05 22.2 0.1 31 4.2 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF1940 PF09155.10 PRP85867.1 - 0.00015 21.9 5.5 18 5.4 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1940) UDP-g_GGTase PF06427.11 PRP85867.1 - 0.00018 21.6 4.7 7.1 6.8 0.1 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 PRP85867.1 - 0.00019 21.2 6.5 15 5.5 0.1 4.3 4 0 0 4 4 4 0 ACT domain Raf1_HTH PF18579.1 PRP85867.1 - 0.0002 21.0 1.4 37 4.1 0.0 4.2 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain DUF969 PF06149.12 PRP85867.1 - 0.00046 19.7 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 PRP85867.1 - 0.0013 19.2 1.9 85 3.8 0.0 4.3 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 PRP85867.1 - 0.003 17.6 0.0 91 3.3 0.0 4.9 4 0 0 4 4 4 0 ORF11CD3 domain Baculo_p48 PF04878.13 PRP85867.1 - 0.007 15.4 0.1 24 3.7 0.0 3.2 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 PRP85867.1 - 0.031 14.4 6.3 70 3.7 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 PRP85867.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif PI3K_p85B PF02192.16 PRP85867.1 - 0.15 11.8 11.0 37 4.2 0.1 4.3 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Myosin_N PF02736.19 PRP85867.1 - 0.31 10.9 6.3 1.1e+02 2.8 0.0 5.0 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 PRP85867.1 - 1.7 8.3 3.5 2.4e+02 1.4 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 Phage_sheath_1N PF17481.2 PRP85867.1 - 2.4 8.7 9.2 1.5e+02 2.9 0.1 3.9 1 1 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 PRP85867.1 - 3.3 6.3 20.6 9.5 4.7 0.6 5.0 5 3 0 5 5 5 0 Plexin cytoplasmic RasGAP domain LRR_9 PF14580.6 PRP85868.1 - 3.8e-12 46.1 0.1 7.1e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PRP85868.1 - 2.9e-06 27.5 8.2 6.2e-05 23.3 6.5 2.8 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP85868.1 - 0.00079 19.1 3.3 0.00079 19.1 3.3 2.5 1 1 2 3 3 3 2 Leucine rich repeat bZIP_1 PF00170.21 PRP85868.1 - 0.016 15.3 0.7 0.016 15.3 0.7 2.8 2 0 0 2 2 2 0 bZIP transcription factor BLOC1_2 PF10046.9 PRP85868.1 - 0.046 14.0 1.4 0.4 11.0 0.2 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LRR_6 PF13516.6 PRP85868.1 - 0.079 13.1 9.3 2.2 8.5 0.2 3.6 3 1 1 4 4 4 0 Leucine Rich repeat Clathrin PF00637.20 PRP85869.1 - 1e-23 83.8 4.5 3.7e-23 82.0 0.1 2.8 2 1 1 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.9 PRP85869.1 - 2.1e-06 28.2 1.8 2.5e-06 27.9 0.3 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 PRP85869.1 - 2.4e-05 24.6 4.8 2.4e-05 24.6 4.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 PRP85869.1 - 0.00065 19.4 3.7 0.0017 18.1 3.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PRP85869.1 - 0.00075 19.5 1.6 0.0021 18.1 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP85869.1 - 0.0036 17.2 2.8 0.0036 17.2 2.8 1.9 2 0 0 2 2 1 1 zinc-RING finger domain WD40_like PF17005.5 PRP85869.1 - 0.0099 15.2 0.1 0.88 8.8 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain zf-C3HC4_2 PF13923.6 PRP85869.1 - 0.018 14.9 0.5 0.018 14.9 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP85869.1 - 0.058 13.3 3.1 0.14 12.0 3.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP85869.1 - 0.14 12.5 0.7 0.47 10.8 0.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PRP85869.1 - 0.24 11.3 7.7 0.074 12.9 4.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 PRP85869.1 - 0.58 10.3 3.5 1.2 9.3 3.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger PHD PF00628.29 PRP85869.1 - 0.97 9.4 10.1 0.039 13.9 2.9 2.4 2 1 1 3 3 3 0 PHD-finger Zf_RING PF16744.5 PRP85869.1 - 1.2 9.3 3.9 4.1 7.6 3.9 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger Prok-RING_1 PF14446.6 PRP85869.1 - 1.3 9.0 8.3 0.12 12.3 2.3 2.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 PRP85869.1 - 1.5 8.9 6.0 4.9 7.3 4.5 2.6 2 1 1 3 3 3 0 Zinc-finger Glyco_hydro_71 PF03659.14 PRP85870.1 - 3.2e-79 266.5 20.0 3.2e-79 266.5 20.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 WSC PF01822.19 PRP85870.1 - 2.8e-10 40.2 15.6 2.8e-10 40.2 15.6 2.8 3 0 0 3 3 3 1 WSC domain zinc_ribbon_12 PF11331.8 PRP85871.1 - 0.015 15.1 0.3 4.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Probable zinc-ribbon domain F-box PF00646.33 PRP85872.1 - 0.00024 20.9 0.3 0.00046 20.0 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP85872.1 - 0.0052 16.6 0.8 0.0094 15.8 0.8 1.4 1 0 0 1 1 1 1 F-box-like Toxin_5 PF05294.13 PRP85872.1 - 0.12 12.8 1.5 0.28 11.6 1.5 1.6 1 0 0 1 1 1 0 Scorpion short toxin Perm-CXXC PF15629.6 PRP85872.1 - 0.22 11.8 2.2 0.47 10.8 2.2 1.5 1 0 0 1 1 1 0 Permuted single zf-CXXC unit Glyco_hydro_71 PF03659.14 PRP85873.1 - 2e-78 263.8 13.4 5.5e-78 262.4 13.4 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.19 PRP85873.1 - 4.2e-19 68.5 39.8 3.2e-09 36.8 16.3 2.8 2 0 0 2 2 2 2 WSC domain F-box-like PF12937.7 PRP85873.1 - 3.4e-07 30.1 1.7 8.9e-07 28.7 1.7 1.7 1 0 0 1 1 1 1 F-box-like DUF3506 PF12014.8 PRP85873.1 - 0.0021 18.0 0.2 0.016 15.2 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) RRM_1 PF00076.22 PRP85874.1 - 2.1e-14 53.1 0.0 4.5e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_mis_repair PF01119.19 PRP85875.1 - 1.8e-21 76.0 1.4 5.2e-21 74.5 1.4 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PRP85875.1 - 3.3e-10 39.9 0.3 6.8e-10 38.9 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PRP85875.1 - 0.00025 21.5 1.2 0.00041 20.8 0.4 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RWD PF05773.22 PRP85875.1 - 0.024 14.9 0.3 0.063 13.6 0.3 1.8 1 0 0 1 1 1 0 RWD domain WHEP-TRS PF00458.20 PRP85875.1 - 0.055 13.6 1.4 0.15 12.3 1.4 1.7 1 0 0 1 1 1 0 WHEP-TRS domain DUF4611 PF15387.6 PRP85875.1 - 0.42 10.9 3.0 1.1 9.5 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FSH1 PF03959.13 PRP85876.1 - 3.3e-31 108.6 0.0 2.4e-30 105.8 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 PRP85876.1 - 0.024 14.4 0.0 0.099 12.4 0.0 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Rhomboid PF01694.22 PRP85877.1 - 6.6e-19 68.4 7.3 1e-18 67.8 7.3 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 PRP85877.1 - 0.0021 18.6 1.8 0.0021 18.6 1.8 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) FRG1 PF06229.12 PRP85878.1 - 3.1e-17 62.9 0.3 1.7e-05 24.6 0.0 3.5 1 1 2 3 3 3 3 FRG1-like domain Fascin PF06268.13 PRP85878.1 - 1.1e-16 61.0 5.1 1.8e-05 24.9 0.3 4.3 1 1 3 4 4 4 4 Fascin domain RicinB_lectin_2 PF14200.6 PRP85878.1 - 3.6e-15 56.5 17.7 0.00012 22.7 0.9 3.9 1 1 4 5 5 5 5 Ricin-type beta-trefoil lectin domain-like DUF569 PF04601.13 PRP85878.1 - 6.3e-10 38.9 0.9 0.009 15.7 0.0 3.8 2 1 0 3 3 3 2 Domain of unknown function (DUF569) Peptidase_M23 PF01551.22 PRP85878.1 - 0.002 18.3 0.6 1.8 8.8 0.1 3.1 2 1 2 4 4 4 2 Peptidase family M23 Inhibitor_I66 PF16850.5 PRP85878.1 - 0.0099 15.8 3.0 0.2 11.5 0.1 2.5 2 0 0 2 2 2 1 Peptidase inhibitor I66 DUF2282 PF10048.9 PRP85878.1 - 0.03 14.3 1.3 32 4.6 0.0 3.5 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2282) ATG11 PF10377.9 PRP85878.1 - 0.056 13.5 2.7 6 7.0 0.7 2.9 2 1 0 2 2 2 0 Autophagy-related protein 11 AAA PF00004.29 PRP85879.1 - 7.2e-16 58.8 0.0 1.5e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PRP85879.1 - 8.6e-05 22.6 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP85879.1 - 0.00012 22.4 0.0 0.00037 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP85879.1 - 0.00027 21.4 0.0 0.0011 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 PRP85879.1 - 0.01 15.7 1.5 0.05 13.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 PRP85879.1 - 0.025 14.8 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 PRP85879.1 - 0.041 14.0 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.6 PRP85879.1 - 0.044 13.5 0.1 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PRP85879.1 - 0.064 12.6 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 PRP85879.1 - 0.11 12.8 0.1 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 PRP85879.1 - 0.12 12.8 0.1 0.91 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 PRP85879.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Glyco_hydro_71 PF03659.14 PRP85880.1 - 2.5e-94 316.2 17.0 4.2e-94 315.4 17.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF1769 PF08588.10 PRP85880.1 - 4.7e-18 65.1 0.0 1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) LRR_6 PF13516.6 PRP85882.1 - 1.4e-28 96.5 23.1 1.5e-05 24.6 0.0 9.8 10 0 0 10 10 10 7 Leucine Rich repeat Lebercilin PF15619.6 PRP85882.1 - 0.00067 19.4 30.5 0.00067 19.4 30.5 4.6 1 1 3 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease Apolipoprotein PF01442.18 PRP85882.1 - 0.0025 17.7 25.1 0.0025 17.7 25.1 4.1 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain LRR_4 PF12799.7 PRP85882.1 - 0.052 14.0 17.7 0.45 11.0 0.0 5.9 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) gerPA PF10676.9 PRP85882.1 - 0.085 13.1 0.7 26 5.2 0.0 3.3 3 0 0 3 3 3 0 Spore germination protein gerPA/gerPF LRR_8 PF13855.6 PRP85882.1 - 0.25 11.2 17.2 2.8 7.7 1.6 5.7 3 2 2 5 5 5 0 Leucine rich repeat APG17 PF04108.12 PRP85882.1 - 1.9 7.5 57.7 0.039 13.1 42.1 2.6 1 1 1 2 2 2 0 Autophagy protein Apg17 Pkinase PF00069.25 PRP85883.1 - 4.2e-67 226.3 0.0 4.2e-67 226.3 0.0 4.0 3 2 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85883.1 - 7.2e-46 156.6 0.0 7.2e-46 156.6 0.0 3.2 3 1 1 4 4 4 2 Protein tyrosine kinase BRD4_CDT PF17105.5 PRP85885.1 - 0.71 9.5 5.2 14 5.4 0.3 3.4 3 0 0 3 3 3 0 C-terminal domain of bromodomain protein 4 F-box-like PF12937.7 PRP85886.1 - 0.0009 19.1 0.8 0.0019 18.1 0.8 1.6 1 0 0 1 1 1 1 F-box-like Ras PF00071.22 PRP85887.1 - 1.5e-36 125.4 0.1 9.7e-24 83.8 0.0 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PRP85887.1 - 7.1e-08 32.7 0.0 0.00016 21.9 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase VWA_2 PF13519.6 PRP85887.1 - 2e-07 31.6 0.4 0.0053 17.4 0.1 3.5 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-Sec23_Sec24 PF04810.15 PRP85887.1 - 1.5e-06 28.2 1.6 4.6e-06 26.6 1.6 1.9 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 PRP85887.1 - 0.0004 21.1 0.1 0.0017 19.0 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Arf PF00025.21 PRP85887.1 - 0.0012 18.3 0.0 0.15 11.5 0.0 2.8 3 0 0 3 3 3 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP85887.1 - 0.0022 17.9 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Sec23_trunk PF04811.15 PRP85887.1 - 0.0062 16.1 0.1 0.086 12.4 0.1 2.3 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain VWA PF00092.28 PRP85887.1 - 0.019 15.2 3.1 0.057 13.7 0.7 2.8 2 1 1 3 3 3 0 von Willebrand factor type A domain WHH PF14414.6 PRP85887.1 - 0.042 13.7 0.2 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH MMS22L_C PF14911.6 PRP85888.1 - 0.0042 16.2 0.1 0.017 14.2 0.1 2.1 1 0 0 1 1 1 1 S-phase genomic integrity recombination mediator, C-terminal HEAT PF02985.22 PRP85888.1 - 0.0091 16.2 0.1 2.4 8.7 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 PRP85888.1 - 0.015 15.8 0.1 42 4.8 0.0 3.9 3 0 0 3 3 3 0 HEAT-like repeat DUF3535 PF12054.8 PRP85888.1 - 0.027 13.7 0.1 0.027 13.7 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3535) Laminin_II PF06009.12 PRP85888.1 - 0.064 13.3 1.7 0.17 11.9 1.7 1.7 1 0 0 1 1 1 0 Laminin Domain II DUF892 PF05974.12 PRP85888.1 - 0.28 11.2 1.4 0.56 10.2 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF892) CLZ PF16526.5 PRP85888.1 - 3 8.3 7.6 0.81 10.1 3.0 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UPF0242 PF06785.11 PRP85888.1 - 3.6 7.7 6.2 7.1 6.7 6.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 PRP85888.1 - 5 7.2 6.6 82 3.3 0.0 2.6 2 0 0 2 2 2 0 FlxA-like protein Fibrillarin PF01269.17 PRP85889.1 - 7e-105 349.2 0.0 9.8e-105 348.7 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin MORN PF02493.20 PRP85889.1 - 3.3e-45 149.3 66.2 2.8e-07 30.0 3.8 11.4 11 0 0 11 11 11 10 MORN repeat zf-C3HC4_3 PF13920.6 PRP85889.1 - 9.6e-11 41.4 11.4 1.6e-10 40.7 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GCD14 PF08704.10 PRP85889.1 - 0.00014 21.6 1.8 0.00017 21.4 0.0 1.8 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Prok-RING_4 PF14447.6 PRP85889.1 - 0.00035 20.4 12.5 0.00064 19.5 12.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RNA_pol_3_Rpc31 PF11705.8 PRP85889.1 - 0.02 15.1 4.2 0.034 14.4 4.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2052 PF09747.9 PRP85889.1 - 0.041 14.0 6.9 0.067 13.3 6.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4366 PF14283.6 PRP85889.1 - 0.19 11.8 7.4 0.33 11.0 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PCMT PF01135.19 PRP85889.1 - 0.38 10.5 1.5 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-RING_2 PF13639.6 PRP85889.1 - 0.5 10.7 15.2 1.2 9.5 15.2 1.7 1 0 0 1 1 1 0 Ring finger domain Paf1 PF03985.13 PRP85889.1 - 0.69 8.9 10.7 0.99 8.3 10.7 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 PRP85889.1 - 2.8 6.0 10.3 4 5.5 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family zf-RING_5 PF14634.6 PRP85889.1 - 5.6 7.0 12.2 12 6.0 12.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DNA_pol_phi PF04931.13 PRP85889.1 - 7 4.6 14.3 9.9 4.1 14.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 PRP85889.1 - 7.8 5.6 9.6 12 5.0 9.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 PRP85889.1 - 9.1 4.4 9.2 13 3.9 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Response_reg PF00072.24 PRP85892.1 - 8.8e-21 74.2 1.5 2.4e-20 72.8 1.5 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 PRP85892.1 - 1.7e-20 73.6 1.5 2.6e-20 73.0 0.4 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP85892.1 - 7.9e-15 54.6 3.4 5.4e-14 52.0 0.1 3.3 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain MASE3 PF17159.4 PRP85892.1 - 4.7e-11 42.7 21.5 1e-10 41.7 21.5 1.6 1 0 0 1 1 1 1 Membrane-associated sensor domain HATPase_c_2 PF13581.6 PRP85892.1 - 0.054 13.5 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain RRM_1 PF00076.22 PRP85893.1 - 7e-31 105.9 0.0 9.6e-16 57.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 PRP85893.1 - 3.1e-07 30.1 1.9 5.1e-07 29.5 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.6 PRP85893.1 - 4.5e-07 29.5 0.1 0.014 15.0 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 PRP85893.1 - 5.5e-06 26.1 2.3 9.7e-06 25.4 2.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RRM_occluded PF16842.5 PRP85893.1 - 3e-05 23.8 0.0 0.038 13.9 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 PRP85893.1 - 3.8e-05 23.7 0.0 0.0035 17.4 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif zf-C3HC4 PF00097.25 PRP85893.1 - 0.00014 21.7 4.2 0.00026 20.8 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP85893.1 - 0.00027 20.8 3.5 0.00054 19.9 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF4523 PF15023.6 PRP85893.1 - 0.0015 18.4 0.1 0.057 13.2 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF4523) zf-C3HC4_2 PF13923.6 PRP85893.1 - 0.0017 18.1 5.6 0.0032 17.3 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_7 PF16367.5 PRP85893.1 - 0.0038 17.3 0.0 2 8.6 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif zf-RING_2 PF13639.6 PRP85893.1 - 0.039 14.3 3.8 0.074 13.4 3.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 PRP85893.1 - 0.088 12.8 4.6 0.18 11.8 4.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Macoilin PF09726.9 PRP85893.1 - 0.25 9.8 15.5 0.36 9.3 15.5 1.0 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 PRP85893.1 - 5.4 5.6 7.7 7.5 5.1 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 PRP85893.1 - 5.4 6.5 27.3 9.5 5.7 27.3 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Glyco_hydro_71 PF03659.14 PRP85894.1 - 4.6e-115 384.4 7.2 4.6e-115 384.4 7.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 PAN_4 PF14295.6 PRP85894.1 - 1.3e-09 37.8 13.3 2.1e-06 27.5 2.0 2.8 2 0 0 2 2 2 2 PAN domain fn3 PF00041.21 PRP85894.1 - 1.2e-08 35.1 0.0 1.6 9.1 0.0 5.1 4 0 0 4 4 4 3 Fibronectin type III domain PAN_2 PF08276.11 PRP85894.1 - 0.072 13.2 10.8 1.6 8.9 1.1 2.8 2 0 0 2 2 2 0 PAN-like domain Pkinase_Tyr PF07714.17 PRP85895.1 - 3.3e-17 62.6 0.7 1.2e-16 60.8 0.7 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85895.1 - 1.5e-10 40.9 1.0 3.6e-10 39.6 1.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP85895.1 - 2.8e-06 27.7 2.8 2.8e-06 27.7 2.8 3.0 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif DUF2755 PF10954.8 PRP85895.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) SR-25 PF10500.9 PRP85895.1 - 8 6.0 13.5 14 5.2 13.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VIT1 PF01988.19 PRP85896.1 - 3e-52 177.6 1.5 3.9e-52 177.2 1.5 1.2 1 0 0 1 1 1 1 VIT family Imm40 PF15569.6 PRP85896.1 - 0.011 15.8 0.1 0.029 14.5 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 40 zf-MYND PF01753.18 PRP85897.1 - 4.6e-11 42.6 18.7 4.6e-11 42.6 18.7 1.7 2 0 0 2 2 2 1 MYND finger SEC-C PF02810.15 PRP85897.1 - 0.00048 20.0 6.5 0.0011 18.8 6.5 1.6 1 0 0 1 1 1 1 SEC-C motif zf-C6H2 PF15801.5 PRP85897.1 - 1.3 9.4 12.8 4 7.8 12.8 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CLTH PF10607.9 PRP85898.1 - 2.2e-34 118.5 3.4 3.1e-34 118.0 3.4 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PRP85898.1 - 4.7e-09 35.9 1.3 8.7e-09 35.0 0.4 2.0 2 0 0 2 2 2 1 LisH TINF2_N PF14973.6 PRP85898.1 - 0.012 16.0 2.7 0.018 15.4 0.2 2.4 2 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus SecA_SW PF07516.13 PRP85898.1 - 0.059 13.4 3.6 0.13 12.3 3.6 1.7 1 1 0 1 1 1 0 SecA Wing and Scaffold domain HTH_57 PF18679.1 PRP85898.1 - 0.8 10.0 4.2 11 6.3 0.0 3.0 3 0 0 3 3 3 0 ThcOx helix turn helix domain Sod_Fe_C PF02777.18 PRP85899.1 - 5.1e-25 87.6 0.5 8.1e-25 87.0 0.5 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Ras PF00071.22 PRP85900.1 - 2.1e-42 144.5 0.2 2.6e-42 144.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP85900.1 - 8.4e-18 64.7 0.1 1.3e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP85900.1 - 1.2e-08 34.6 0.1 1.5e-08 34.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP85900.1 - 0.0007 19.2 0.0 0.0014 18.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Forkhead PF00250.18 PRP85901.1 - 1.2e-12 47.9 0.6 8.6e-09 35.5 0.1 3.2 3 0 0 3 3 3 2 Forkhead domain Rhabdo_NV PF02484.15 PRP85901.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Rhabdovirus Non-virion protein Peptidase_S64 PF08192.11 PRP85901.1 - 4.3 5.7 24.2 8.2 4.8 24.2 1.5 1 0 0 1 1 1 0 Peptidase family S64 Pkinase_Tyr PF07714.17 PRP85902.1 - 1.6e-46 158.7 2.6 2e-30 106.0 0.3 3.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP85902.1 - 5.4e-29 101.4 0.0 5e-27 94.9 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Hydrolase_like PF13242.6 PRP85902.1 - 9e-19 67.3 0.0 2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 PRP85902.1 - 5.6e-06 26.6 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TMEM154 PF15102.6 PRP85902.1 - 0.0023 17.8 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DAG1 PF05454.11 PRP85902.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) ASL_C PF08328.11 PRP85902.1 - 0.028 14.5 0.1 0.056 13.5 0.1 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Orf78 PF06024.12 PRP85902.1 - 0.084 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Insulin_TMD PF17870.1 PRP85902.1 - 0.11 12.6 0.7 0.25 11.4 0.7 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF1180 PF06679.12 PRP85902.1 - 0.12 12.7 0.3 0.23 11.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF5129 PF17173.4 PRP85902.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) EphA2_TM PF14575.6 PRP85902.1 - 0.14 13.0 1.5 0.38 11.6 1.5 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 PRP85902.1 - 0.22 11.0 0.0 0.46 10.0 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ECSCR PF15820.5 PRP85902.1 - 0.23 11.3 2.5 0.49 10.2 2.1 1.7 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Ribosom_S12_S23 PF00164.25 PRP85903.1 - 0.13 11.8 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein S12/S23 Complex1_LYR_2 PF13233.6 PRP85906.1 - 1.5e-13 51.3 3.1 2e-13 50.9 3.1 1.2 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 PRP85906.1 - 0.0089 16.1 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Arc_C PF18162.1 PRP85906.1 - 0.02 14.7 1.7 0.53 10.2 0.4 2.3 1 1 1 2 2 2 0 Arc C-lobe DUF3072 PF11272.8 PRP85906.1 - 0.057 13.3 0.7 1.5 8.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3072) BCAS2 PF05700.11 PRP85906.1 - 0.074 12.7 7.0 1.3 8.6 7.0 2.0 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF2680 PF10925.8 PRP85906.1 - 0.91 9.6 7.7 0.21 11.6 3.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Nup54_57_C PF18570.1 PRP85906.1 - 2.8 7.6 8.2 0.21 11.2 2.9 1.9 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain BTB_2 PF02214.22 PRP85907.1 - 4.2e-14 52.7 0.4 9.7e-14 51.5 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain Syntaxin PF00804.25 PRP85907.1 - 0.0039 16.9 2.3 0.0039 16.9 2.3 2.3 2 0 0 2 2 2 1 Syntaxin DUF5069 PF16798.5 PRP85907.1 - 0.15 12.2 2.3 0.38 11.0 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) HetR_C PF18460.1 PRP85907.1 - 0.42 10.6 4.7 0.15 12.0 1.2 2.1 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain KASH_CCD PF14662.6 PRP85907.1 - 0.5 10.2 16.0 22 4.8 16.1 2.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 PRP85907.1 - 0.51 9.2 15.0 1.1 8.1 15.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF573 PF04504.14 PRP85907.1 - 0.57 10.9 6.1 2 9.1 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function, DUF573 TMF_TATA_bd PF12325.8 PRP85907.1 - 0.64 10.3 17.7 0.15 12.3 11.5 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 PRP85907.1 - 0.69 10.1 5.2 2.6 8.2 1.9 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 PRP85907.1 - 0.74 8.8 10.7 0.22 10.6 5.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 PRP85907.1 - 3.1 7.1 13.9 2.2 7.6 5.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 PRP85907.1 - 4.1 8.1 10.2 2.3 8.9 1.7 3.6 2 1 2 4 4 4 0 Initiation control protein YabA GTP_EFTU PF00009.27 PRP85908.1 - 2.5e-59 200.1 0.1 4.1e-59 199.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PRP85908.1 - 1.5e-19 70.0 0.0 4.2e-19 68.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 PRP85908.1 - 2.7e-19 69.0 0.0 6.7e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 PRP85908.1 - 1.8e-12 47.2 0.4 2.9e-09 36.9 0.0 3.1 3 0 0 3 3 3 2 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 PRP85908.1 - 1e-10 41.8 0.0 2.9e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Cupin_2 PF07883.11 PRP85908.1 - 1.4e-09 37.5 0.3 4e-09 36.1 0.3 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 PRP85908.1 - 8.5e-05 22.2 0.0 0.00026 20.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF861) MMR_HSR1 PF01926.23 PRP85908.1 - 0.00038 20.5 0.1 0.0008 19.5 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AraC_binding PF02311.19 PRP85908.1 - 0.00052 19.9 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.7 PRP85908.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Cupin RhoGEF PF00621.20 PRP85909.1 - 1.4e-35 123.1 0.0 3.7e-35 121.8 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain MyTH4 PF00784.17 PRP85909.1 - 1.1e-09 38.7 0.1 4e-09 36.9 0.1 1.9 1 0 0 1 1 1 1 MyTH4 domain PH PF00169.29 PRP85909.1 - 9.2e-05 22.9 1.0 0.00048 20.6 0.0 2.7 3 0 0 3 3 3 1 PH domain PAS_8 PF13188.7 PRP85909.1 - 0.00031 20.7 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain Aldedh PF00171.22 PRP85911.1 - 5e-133 444.0 0.3 5.9e-133 443.7 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ZYG-11_interact PF05884.12 PRP85911.1 - 0.11 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 Pkinase_Tyr PF07714.17 PRP85913.1 - 8.3e-69 231.7 0.0 1.1e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP85913.1 - 1.4e-40 139.3 0.0 2.1e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP85913.1 - 2.8e-20 71.8 58.7 3.2e-07 30.0 3.8 9.7 5 2 5 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 PRP85913.1 - 2.2e-18 66.0 64.1 0.0034 17.8 7.9 11.6 7 3 7 15 15 15 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP85913.1 - 0.00022 21.3 59.4 17 6.5 0.1 16.7 16 2 0 16 16 16 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP85913.1 - 0.012 15.6 54.7 8.7 6.7 0.0 15.0 17 0 0 17 17 17 0 Leucine Rich repeat Pkinase_fungal PF17667.1 PRP85913.1 - 0.023 13.5 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Syndecan PF01034.20 PRP85913.1 - 0.026 14.4 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 PRP85913.1 - 0.14 13.1 0.0 0.35 11.8 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PTP_tm PF18861.1 PRP85913.1 - 1.8 8.5 3.7 3.1 7.8 2.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Cadherin_C_2 PF16492.5 PRP85914.1 - 0.053 14.3 0.1 0.074 13.8 0.1 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal zf-CCCH_4 PF18044.1 PRP85915.1 - 0.0023 17.7 4.2 0.0045 16.8 4.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger HGTP_anticodon PF03129.20 PRP85915.1 - 0.0043 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain zf-RanBP PF00641.18 PRP85915.1 - 0.0058 15.9 7.1 0.015 14.6 7.1 1.8 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C6H2 PF15801.5 PRP85915.1 - 0.011 16.0 6.3 0.011 16.0 6.3 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf_CCCH_4 PF18345.1 PRP85915.1 - 0.035 14.2 7.5 0.076 13.1 7.5 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-MYND PF01753.18 PRP85915.1 - 8.6 6.6 18.9 0.026 14.6 6.9 2.6 2 0 0 2 2 2 0 MYND finger Acetyltransf_4 PF13420.7 PRP85916.1 - 8.6e-21 74.7 0.0 7.2e-20 71.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP85916.1 - 1e-07 32.7 0.0 1.4e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP85916.1 - 0.00065 19.9 0.0 0.45 10.8 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP85916.1 - 0.0017 18.3 0.0 0.82 9.6 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP85916.1 - 0.18 11.8 0.0 0.51 10.3 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Fcf1 PF04900.12 PRP85917.1 - 2e-08 34.5 0.1 5.7e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 Fcf1 WD40 PF00400.32 PRP85918.1 - 1.2e-29 101.9 22.1 0.0014 19.4 0.0 12.3 12 1 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP85918.1 - 7.1e-09 35.9 0.1 0.69 10.2 0.0 6.5 4 3 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP85918.1 - 0.0023 16.8 0.2 5.2 5.7 0.1 4.8 3 2 2 5 5 5 1 Nup133 N terminal like LIAS_N PF16881.5 PRP85918.1 - 0.015 15.7 0.0 1.5 9.3 0.1 3.3 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family EF-hand_1 PF00036.32 PRP85918.1 - 0.017 14.6 2.0 0.061 12.9 1.3 2.3 2 0 0 2 2 2 0 EF hand Ge1_WD40 PF16529.5 PRP85918.1 - 0.018 14.0 0.0 8.4 5.2 0.0 3.9 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_6 PF13405.6 PRP85918.1 - 0.12 12.4 0.4 0.4 10.7 0.4 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 PRP85918.1 - 0.13 12.7 1.4 0.5 10.9 1.4 2.0 1 1 0 1 1 1 0 EF-hand domain pair SURF1 PF02104.15 PRP85919.1 - 7.8e-40 137.0 0.0 1.6e-39 136.0 0.0 1.5 1 0 0 1 1 1 1 SURF1 family HATPase_c PF02518.26 PRP85919.1 - 1.4e-26 93.2 0.2 2.5e-26 92.4 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP85919.1 - 2e-25 89.2 1.2 5.1e-25 87.8 1.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 PRP85919.1 - 2.5e-14 53.0 0.2 6.9e-14 51.6 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 PRP85919.1 - 2.3e-05 24.7 0.0 0.00013 22.3 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_9 PF13426.7 PRP85919.1 - 0.00022 21.4 0.0 0.02 15.1 0.0 3.5 3 1 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 PRP85919.1 - 0.0009 19.1 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 PRP85919.1 - 0.023 15.3 0.0 0.07 13.8 0.0 1.9 1 0 0 1 1 1 0 GAF domain GAF_3 PF13492.6 PRP85919.1 - 0.038 14.3 0.0 0.083 13.2 0.0 1.6 1 0 0 1 1 1 0 GAF domain YwhD PF08741.10 PRP85919.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 YwhD family NAD_binding_10 PF13460.6 PRP85920.1 - 0.0061 16.5 0.0 0.067 13.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 PRP85920.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Gly_transf_sug PF04488.15 PRP85922.1 - 1.4e-10 41.7 0.1 3.6e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif zf-LITAF-like PF10601.9 PRP85923.1 - 1e-22 80.2 14.5 1.5e-22 79.6 14.5 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Sgf11 PF08209.11 PRP85923.1 - 0.03 13.9 2.4 0.051 13.2 0.2 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Herpes_LMP2 PF07415.11 PRP85923.1 - 1.2 7.8 7.5 1.5 7.5 7.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DNA_pol3_delta2 PF13177.6 PRP85924.1 - 2.5e-14 53.4 0.1 4.6e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 PRP85924.1 - 6.6e-08 33.1 0.2 2.1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PRP85924.1 - 2.3e-07 30.9 0.1 5.8e-07 29.6 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 PRP85924.1 - 2.4e-06 27.4 0.1 6.1e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 PRP85924.1 - 0.00022 21.6 0.1 0.0037 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PRP85924.1 - 0.00075 19.5 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 PRP85924.1 - 0.003 16.8 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 PRP85924.1 - 0.0059 17.1 0.0 0.0091 16.5 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Sigma54_activ_2 PF14532.6 PRP85924.1 - 0.0079 16.3 1.3 0.11 12.7 0.2 2.9 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.14 PRP85924.1 - 0.0099 16.0 0.8 0.068 13.3 0.2 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rep_fac_C PF08542.11 PRP85924.1 - 0.011 16.1 0.6 0.11 12.9 0.0 2.8 3 1 0 3 3 2 0 Replication factor C C-terminal domain AAA_22 PF13401.6 PRP85924.1 - 0.018 15.3 1.1 1.1 9.5 0.2 3.0 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PRP85924.1 - 0.048 13.0 0.1 0.16 11.3 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI PRK PF00485.18 PRP85924.1 - 0.055 13.2 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RuvB_N PF05496.12 PRP85924.1 - 0.066 13.0 0.1 0.89 9.3 0.0 2.3 1 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 PRP85924.1 - 0.07 12.8 0.2 0.31 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 PRP85924.1 - 0.073 12.8 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 PRP85924.1 - 0.11 13.0 0.3 0.31 11.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain SPRY PF00622.28 PRP85925.1 - 6.9e-14 52.0 0.1 1.4e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 PRP85925.1 - 5.6e-07 29.4 1.5 1.4e-06 28.1 1.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP85925.1 - 1.3 8.9 6.0 1.8 8.5 4.1 2.2 2 1 0 2 2 2 0 F-box domain PseudoU_synth_1 PF01416.20 PRP85926.1 - 1.4e-07 32.0 0.0 3.4e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Rieske PF00355.26 PRP85927.1 - 5.3e-12 45.5 0.0 7.1e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PRP85927.1 - 9.6e-11 41.5 0.0 1.8e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain FtsQ PF03799.15 PRP85927.1 - 0.15 12.9 0.0 0.23 12.3 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsQ EamA PF00892.20 PRP85928.1 - 3.2e-26 92.1 31.9 9.3e-15 55.0 9.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family Mg_trans_NIPA PF05653.14 PRP85928.1 - 7.8e-05 21.9 1.5 7.8e-05 21.9 1.5 2.1 2 0 0 2 2 2 1 Magnesium transporter NIPA Myotub-related PF06602.14 PRP85929.1 - 2.1e-117 392.0 0.5 3.6e-117 391.2 0.0 1.6 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain FYVE PF01363.21 PRP85929.1 - 2.2e-14 53.4 23.5 4.4e-14 52.4 23.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Y_phosphatase PF00102.27 PRP85929.1 - 0.00028 20.5 0.6 0.0011 18.6 0.1 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP85929.1 - 0.0031 17.5 0.0 0.009 16.0 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 PRP85929.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PHM7_cyt PF14703.6 PRP85929.1 - 0.058 13.6 0.7 0.25 11.6 0.7 2.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Tropomyosin_1 PF12718.7 PRP85929.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Tropomyosin like BTB_2 PF02214.22 PRP85931.1 - 4.4e-07 30.2 0.1 6.2e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain TIM PF00121.18 PRP85933.1 - 9e-86 287.2 0.1 1e-85 287.0 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase SNARE PF05739.19 PRP85934.1 - 6e-16 58.2 1.1 6e-16 58.2 1.1 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 PRP85934.1 - 1.4e-05 24.9 16.7 0.00041 20.1 16.8 2.6 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 PRP85934.1 - 0.11 12.9 18.6 0.63 10.5 1.1 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Myb_DNA-bind_5 PF13873.6 PRP85934.1 - 0.49 10.5 4.4 2.5 8.2 0.1 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ETRAMP PF09716.10 PRP85934.1 - 0.79 9.8 7.0 60 3.8 7.1 3.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Sulfatase_C PF14707.6 PRP85934.1 - 1.2 9.8 3.0 9.9 6.9 0.1 3.2 2 2 1 3 3 3 0 C-terminal region of aryl-sulfatase PRP1_N PF06424.12 PRP85934.1 - 2.5 8.5 10.2 0.25 11.8 2.8 2.4 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal DUF4041 PF13250.6 PRP85934.1 - 4 7.4 7.0 2.2 8.2 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) DUF2203 PF09969.9 PRP85934.1 - 5.1 7.8 14.2 27 5.5 1.5 3.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3552 PF12072.8 PRP85934.1 - 6.5 6.1 22.0 0.27 10.6 5.8 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF3552) Med9 PF07544.13 PRP85934.1 - 7.1 6.8 23.7 3.3 7.9 0.2 5.0 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Snapin_Pallidin PF14712.6 PRP85935.1 - 7.3e-17 61.6 2.8 1.1e-16 61.0 2.8 1.3 1 0 0 1 1 1 1 Snapin/Pallidin DUF948 PF06103.11 PRP85935.1 - 1.5e-05 25.2 1.2 0.0061 16.8 1.2 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 PRP85935.1 - 0.00024 21.1 1.5 0.00032 20.7 1.5 1.1 1 0 0 1 1 1 1 Laminin Domain II DUF16 PF01519.16 PRP85935.1 - 0.00024 21.5 2.7 0.00032 21.1 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 DUF489 PF04356.12 PRP85935.1 - 0.0017 18.4 0.2 0.0021 18.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF489) DUF1664 PF07889.12 PRP85935.1 - 0.0027 17.7 1.6 0.004 17.2 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) RIH_assoc PF08454.11 PRP85935.1 - 0.0065 16.3 0.7 0.0086 15.9 0.7 1.3 1 0 0 1 1 1 1 RyR and IP3R Homology associated Syntaxin PF00804.25 PRP85935.1 - 0.008 15.9 0.8 0.011 15.4 0.8 1.2 1 0 0 1 1 1 1 Syntaxin Fib_alpha PF08702.10 PRP85935.1 - 0.008 16.4 3.8 0.013 15.7 3.6 1.4 1 1 0 1 1 1 1 Fibrinogen alpha/beta chain family Allexi_40kDa PF05549.11 PRP85935.1 - 0.012 15.2 0.9 0.013 15.0 0.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF745 PF05335.13 PRP85935.1 - 0.016 14.9 0.5 0.023 14.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) IFT57 PF10498.9 PRP85935.1 - 0.019 13.9 2.1 0.023 13.7 2.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 EzrA PF06160.12 PRP85935.1 - 0.02 13.1 2.0 0.025 12.8 2.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 PRP85935.1 - 0.021 14.4 0.4 0.022 14.3 0.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3037 PF11236.8 PRP85935.1 - 0.021 15.3 0.3 1.6 9.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DivIVA PF05103.13 PRP85935.1 - 0.022 14.9 2.3 0.039 14.0 2.3 1.5 1 1 0 1 1 1 0 DivIVA protein Rsd_AlgQ PF04353.13 PRP85935.1 - 0.022 14.7 0.2 0.03 14.3 0.2 1.2 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ LOH1CR12 PF10158.9 PRP85935.1 - 0.022 14.8 0.2 0.027 14.5 0.2 1.1 1 0 0 1 1 1 0 Tumour suppressor protein YkyA PF10368.9 PRP85935.1 - 0.022 14.4 2.0 0.03 14.0 2.0 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Baculo_PEP_C PF04513.12 PRP85935.1 - 0.023 14.7 0.5 0.034 14.2 0.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3418 PF11898.8 PRP85935.1 - 0.032 12.9 0.0 0.035 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) GIT_CC PF16559.5 PRP85935.1 - 0.034 14.0 0.5 0.034 14.0 0.5 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor GCN5L1 PF06320.13 PRP85935.1 - 0.035 14.2 0.9 0.08 13.1 0.9 1.6 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) KxDL PF10241.9 PRP85935.1 - 0.038 14.3 5.1 0.079 13.3 5.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein FapA PF03961.13 PRP85935.1 - 0.042 12.5 1.2 0.047 12.3 1.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4201 PF13870.6 PRP85935.1 - 0.047 13.4 3.9 0.062 13.0 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DASH_Duo1 PF08651.10 PRP85935.1 - 0.079 12.7 1.7 1.9 8.3 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 Sec8_exocyst PF04048.14 PRP85935.1 - 0.086 12.7 3.2 2.3 8.1 0.9 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain MCPsignal PF00015.21 PRP85935.1 - 0.096 12.5 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ATG16 PF08614.11 PRP85935.1 - 0.12 12.6 4.4 0.15 12.2 3.6 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 PRP85935.1 - 0.13 11.5 4.2 0.18 11.1 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TolA_bind_tri PF16331.5 PRP85935.1 - 0.14 12.3 7.3 36 4.5 7.3 3.0 2 1 0 2 2 2 0 TolA binding protein trimerisation TMPIT PF07851.13 PRP85935.1 - 0.14 11.3 1.1 0.18 11.1 1.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Fzo_mitofusin PF04799.13 PRP85935.1 - 0.23 11.0 3.1 0.44 10.1 2.9 1.6 1 1 0 1 1 1 0 fzo-like conserved region FlaC_arch PF05377.11 PRP85935.1 - 0.85 10.1 4.8 1.5 9.3 1.2 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dam1 PF08653.10 PRP85935.1 - 2.3 8.1 4.3 15 5.5 0.3 2.7 1 1 2 3 3 3 0 DASH complex subunit Dam1 Acetyltransf_7 PF13508.7 PRP85936.1 - 0.00025 21.4 0.0 0.00046 20.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP85936.1 - 0.00043 20.5 0.0 0.00087 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PRP85936.1 - 0.00099 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 PRP85936.1 - 0.0036 17.2 0.1 0.0093 15.9 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain UQ_con PF00179.26 PRP85937.1 - 3.6e-47 159.6 0.0 4e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PRP85937.1 - 0.0084 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 PRP85937.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain ATG16 PF08614.11 PRP85938.1 - 2.6e-05 24.5 47.8 0.012 15.8 11.3 4.1 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) SYCE1 PF15233.6 PRP85938.1 - 0.0062 16.6 6.0 0.0062 16.6 6.0 3.6 2 1 0 3 3 3 1 Synaptonemal complex central element protein 1 Fib_alpha PF08702.10 PRP85938.1 - 0.33 11.1 34.4 0.078 13.2 13.1 3.1 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family HAP1_N PF04849.13 PRP85938.1 - 0.5 9.5 42.4 0.14 11.4 4.5 3.4 2 1 2 4 4 4 0 HAP1 N-terminal conserved region Hrs_helical PF12210.8 PRP85938.1 - 0.77 10.3 28.8 0.59 10.7 4.4 3.7 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate FUSC PF04632.12 PRP85938.1 - 1.5 7.2 12.6 3.3 6.1 12.6 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF5314 PF17241.2 PRP85938.1 - 1.6 8.4 12.9 0.52 10.0 1.5 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5314) TPR_MLP1_2 PF07926.12 PRP85938.1 - 1.9 8.6 47.7 0.96 9.5 18.1 4.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 PRP85938.1 - 2.4 8.2 45.9 2.4 8.2 14.7 5.6 3 2 2 5 5 5 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 PRP85938.1 - 2.6 7.2 31.0 1.6 7.9 11.1 2.3 1 1 0 2 2 2 0 TMPIT-like protein ERM PF00769.19 PRP85938.1 - 2.7 7.7 44.4 1.1 9.1 23.8 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 PRP85938.1 - 3.1 6.3 34.7 0.34 9.5 2.5 2.3 1 1 2 3 3 3 0 AAA domain GAS PF13851.6 PRP85938.1 - 5.7 6.2 51.2 0.72 9.2 14.7 4.2 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Acetyltransf_1 PF00583.25 PRP85940.1 - 3e-12 46.8 0.0 4.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP85940.1 - 9.2e-07 29.2 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP85940.1 - 0.0007 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP85940.1 - 0.021 14.9 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Laterosporulin PF17861.1 PRP85940.1 - 0.029 14.8 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Laterosporulin defensin-like peptide Acetyltransf_6 PF13480.7 PRP85940.1 - 0.037 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PRP85940.1 - 0.038 14.1 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP85940.1 - 0.068 13.2 0.0 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein GNAT_acetyltran PF12746.7 PRP85940.1 - 0.16 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_CG PF14542.6 PRP85940.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase adh_short PF00106.25 PRP85941.1 - 8.7e-16 57.9 0.0 3.2e-14 52.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP85941.1 - 2.6e-06 27.2 0.0 3.1e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP85941.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP85941.1 - 0.028 13.9 0.0 0.084 12.3 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glu_dehyd_C PF16912.5 PRP85941.1 - 0.092 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus EF-hand_1 PF00036.32 PRP85942.1 - 1.6e-18 64.8 0.5 0.00015 21.1 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PRP85942.1 - 3.5e-14 51.4 2.6 0.00042 20.0 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 PRP85942.1 - 1.5e-12 47.8 1.9 5.4e-06 26.8 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP85942.1 - 1e-11 43.7 2.8 3.3e-05 23.2 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PRP85942.1 - 2.3e-10 40.2 0.2 0.0016 18.3 0.0 3.4 3 1 0 3 3 3 3 EF-hand domain pair DUF5495 PF17599.2 PRP85942.1 - 0.086 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5495) DUF1907 PF08925.11 PRP85943.1 - 3.2e-86 289.3 0.0 3.6e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) zf-MYND PF01753.18 PRP85944.1 - 5.2e-11 42.4 12.0 9.3e-11 41.6 12.0 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 PRP85944.1 - 0.73 10.2 8.2 1.8 8.9 8.2 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-C2HCIx2C PF10782.9 PRP85944.1 - 7.3 6.6 7.4 3 7.9 4.3 2.0 2 0 0 2 2 2 0 Zinc-finger PAN_4 PF14295.6 PRP85945.1 - 3.2e-35 119.8 51.5 3.4e-08 33.3 2.7 6.5 6 0 0 6 6 6 5 PAN domain Peptidase_C1 PF00112.23 PRP85945.1 - 1.1e-30 107.4 4.7 1.1e-30 107.4 4.7 1.9 2 0 0 2 2 2 1 Papain family cysteine protease PAN_1 PF00024.26 PRP85945.1 - 2e-23 82.1 38.5 6e-05 22.9 0.8 5.8 6 0 0 6 6 6 5 PAN domain PAN_2 PF08276.11 PRP85945.1 - 0.0001 22.4 50.2 0.28 11.3 2.5 5.8 5 0 0 5 5 5 5 PAN-like domain 3HCDH PF00725.22 PRP85945.1 - 0.097 13.3 0.0 8.5 7.1 0.0 2.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF4185 PF13810.6 PRP85946.1 - 2.8e-25 89.2 30.3 5.9e-13 48.7 11.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4185) RicinB_lectin_2 PF14200.6 PRP85946.1 - 2.7e-20 72.9 19.6 4.4e-09 36.9 1.8 5.2 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain-like GnHR_trans PF12369.8 PRP85946.1 - 0.00051 20.8 0.2 2 9.3 0.0 2.5 2 0 0 2 2 2 2 Gonadotropin hormone receptor transmembrane region CDtoxinA PF03498.14 PRP85946.1 - 0.00093 18.8 14.1 0.017 14.7 0.2 3.6 4 0 0 4 4 4 2 Cytolethal distending toxin A/C domain DUF4939 PF16297.5 PRP85946.1 - 0.034 14.0 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) TcfC PF16967.5 PRP85947.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 E-set like domain Ependymin PF00811.18 PRP85947.1 - 0.06 13.6 0.1 0.1 12.8 0.1 1.5 1 1 0 1 1 1 0 Ependymin FERM_M PF00373.18 PRP85948.1 - 7.2e-07 29.6 0.0 1.4e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 FERM central domain PsbK PF02533.15 PRP85948.1 - 0.2 11.8 0.0 1.2 9.4 0.0 2.0 2 0 0 2 2 2 0 Photosystem II 4 kDa reaction centre component LZ3wCH PF18517.1 PRP85948.1 - 0.21 11.7 2.1 0.96 9.6 0.0 2.6 3 0 0 3 3 3 0 Leucine zipper with capping helix domain Methyltransf_10 PF05971.12 PRP85949.1 - 5.9e-71 239.2 0.4 6.2e-70 235.9 0.4 2.0 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 PRP85949.1 - 4.6e-07 29.5 0.0 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Beta_helix PF13229.6 PRP85950.1 - 0.00046 20.1 20.4 0.00088 19.2 0.5 4.3 3 2 1 4 4 4 2 Right handed beta helix region NosD PF05048.13 PRP85950.1 - 0.063 12.5 11.3 0.096 11.9 0.2 2.7 2 1 1 3 3 3 0 Periplasmic copper-binding protein (NosD) DUF4477 PF14780.6 PRP85951.1 - 0.011 15.4 2.1 0.012 15.2 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) DUF1801 PF08818.11 PRP85951.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DU1801) FAD_binding_3 PF01494.19 PRP85952.1 - 9.9e-15 54.6 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP85952.1 - 6.9e-05 22.2 0.0 0.00044 19.6 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP85952.1 - 0.00018 21.2 0.2 0.0026 17.4 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 PRP85952.1 - 0.00054 20.5 0.0 0.13 12.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PRP85952.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 PRP85952.1 - 0.0026 18.0 0.1 0.0061 16.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF4268 PF14088.6 PRP85952.1 - 0.0045 16.9 0.1 0.21 11.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4268) FAD_binding_2 PF00890.24 PRP85952.1 - 0.044 12.9 0.1 0.11 11.5 0.1 1.6 1 1 0 1 1 1 0 FAD binding domain SPX PF03105.19 PRP85954.1 - 0.046 13.6 0.8 0.054 13.4 0.8 1.1 1 0 0 1 1 1 0 SPX domain WD40_alt PF14077.6 PRP85954.1 - 0.061 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Pkinase PF00069.25 PRP85956.1 - 9.7e-44 149.7 0.0 1.1e-25 90.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85956.1 - 1.7e-16 60.3 0.0 5.2e-13 48.9 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PRP85956.1 - 0.00032 20.7 0.0 0.0012 18.8 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP85956.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IcmF_C PF06744.12 PRP85956.1 - 0.026 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal FTA2 PF13095.6 PRP85956.1 - 0.16 11.6 0.0 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 His_Phos_1 PF00300.22 PRP85957.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Ribosomal_L14 PF00238.19 PRP85958.1 - 1.3e-36 125.4 0.0 1.5e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Y_phosphatase PF00102.27 PRP85959.1 - 5.4e-80 268.3 0.2 6.7e-80 268.0 0.2 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PRP85959.1 - 4e-06 26.7 0.0 8.1e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PRP85959.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 PRP85959.1 - 0.00041 20.5 0.0 0.00085 19.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Robl_LC7 PF03259.17 PRP85961.1 - 4.2e-05 23.2 0.0 6.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain Profilin PF00235.19 PRP85961.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.5 1 1 0 1 1 1 0 Profilin SMN PF06003.12 PRP85962.1 - 6.6e-06 25.6 13.1 0.00038 19.8 0.0 2.6 2 1 0 2 2 2 2 Survival motor neuron protein (SMN) Pkinase PF00069.25 PRP85963.1 - 2.2e-55 187.9 0.0 2.6e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP85963.1 - 4.1e-27 95.1 0.0 5.3e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP85963.1 - 0.00086 19.3 0.1 0.0019 18.2 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP85963.1 - 0.058 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 PRP85963.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 PRP85963.1 - 0.23 10.5 0.1 0.42 9.6 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 EF-hand_1 PF00036.32 PRP85964.1 - 9.2e-22 74.9 0.2 4.5e-06 25.8 0.1 4.9 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 PRP85964.1 - 2.8e-21 74.0 0.0 1.5e-05 24.2 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PRP85964.1 - 6.2e-18 63.1 0.1 0.0024 17.7 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 PRP85964.1 - 4.2e-17 62.4 0.1 2.7e-08 34.2 0.2 3.2 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP85964.1 - 1.6e-12 47.1 0.1 0.0012 18.6 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_10 PF14788.6 PRP85964.1 - 0.00058 19.7 0.2 4 7.4 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 PRP85964.1 - 0.043 13.8 0.6 0.96 9.4 0.3 2.8 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 PRP85964.1 - 0.053 13.5 0.3 3.2 7.6 0.0 2.7 2 1 1 3 3 3 0 Caleosin related protein PhageMin_Tail PF10145.9 PRP85964.1 - 0.14 12.0 0.4 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Phage-related minor tail protein TFIIA PF03153.13 PRP85964.1 - 3.5 7.5 14.9 4.1 7.3 14.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LMF1 PF06762.14 PRP85965.1 - 4.8e-111 372.0 7.1 6.4e-111 371.6 7.1 1.1 1 0 0 1 1 1 1 Lipase maturation factor DUF1211 PF06736.11 PRP85965.1 - 0.041 14.3 0.7 0.24 11.9 0.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) RRM_1 PF00076.22 PRP85966.1 - 2.7e-16 59.1 0.1 4.1e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PRP85966.1 - 3e-07 30.2 4.4 5.6e-07 29.4 4.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Nup35_RRM_2 PF14605.6 PRP85966.1 - 0.002 18.1 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 PRP85966.1 - 0.003 17.1 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.6 PRP85966.1 - 0.0086 16.0 0.2 0.016 15.1 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 PRP85966.1 - 0.018 15.2 0.0 0.31 11.2 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif SET_assoc PF11767.8 PRP85966.1 - 0.019 14.6 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated PHM7_cyt PF14703.6 PRP85966.1 - 0.036 14.3 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DbpA PF03880.15 PRP85966.1 - 0.051 13.6 0.1 0.079 13.0 0.1 1.3 1 0 0 1 1 1 0 DbpA RNA binding domain K_trans PF02705.16 PRP85968.1 - 7e-130 434.0 2.3 5.1e-129 431.2 2.3 1.9 1 1 0 1 1 1 1 K+ potassium transporter DUF998 PF06197.13 PRP85968.1 - 0.011 15.3 1.9 0.011 15.3 1.9 3.4 3 2 1 4 4 4 0 Protein of unknown function (DUF998) AA_kinase PF00696.28 PRP85969.1 - 0.047 13.3 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Amino acid kinase family MAP65_ASE1 PF03999.12 PRP85969.1 - 1.6 7.4 3.5 2.3 6.8 3.5 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Peptidase_S28 PF05577.12 PRP85970.1 - 1.1e-77 261.7 0.8 1.7e-77 261.1 0.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S28 PF05577.12 PRP85972.1 - 4.6e-90 302.5 6.5 7.6e-90 301.8 6.5 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 PRP85972.1 - 3.3e-08 32.6 2.6 6.6e-08 31.6 2.6 1.6 1 1 0 1 1 1 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 PRP85972.1 - 0.0005 19.4 0.0 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Carb_bind PF10645.9 PRP85972.1 - 0.014 15.6 36.2 0.081 13.2 5.2 3.8 2 1 1 3 3 3 0 Carbohydrate binding Peptidase_S9 PF00326.21 PRP85972.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4055 PF13264.6 PRP85972.1 - 0.14 12.3 1.7 0.73 10.0 1.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Abhydrolase_3 PF07859.13 PRP85972.1 - 0.27 11.0 0.0 0.27 11.0 0.0 2.1 3 0 0 3 3 3 0 alpha/beta hydrolase fold SPX PF03105.19 PRP85972.1 - 0.37 10.7 16.9 0.7 9.7 16.9 1.4 1 0 0 1 1 1 0 SPX domain Utp14 PF04615.13 PRP85972.1 - 5.8 5.4 6.2 8.7 4.8 6.2 1.2 1 0 0 1 1 1 0 Utp14 protein 2OG-FeII_Oxy_2 PF13532.6 PRP85973.1 - 3e-17 63.4 0.0 7.2e-17 62.2 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CoA_binding PF02629.19 PRP85975.1 - 4.2e-31 107.5 1.1 1.1e-30 106.2 1.1 1.7 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 PRP85975.1 - 2.5e-21 76.1 0.2 4.1e-21 75.4 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 PRP85975.1 - 6.4e-11 42.2 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 PRP85975.1 - 0.0025 18.3 0.0 0.0069 16.9 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Pmp3 PF01679.17 PRP85975.1 - 0.19 11.9 0.7 3.6 7.9 0.4 2.5 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Skp1_POZ PF03931.15 PRP85976.1 - 4.6e-21 74.8 0.4 7.2e-21 74.1 0.4 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 PRP85976.1 - 1.4e-16 60.3 1.4 1.6e-16 60.1 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain BTB PF00651.31 PRP85976.1 - 0.019 15.2 0.1 6.7 7.0 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain ExsD PF16806.5 PRP85976.1 - 0.024 14.6 0.1 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 Antiactivator protein ExsD DUF3140 PF11338.8 PRP85976.1 - 0.072 13.5 0.5 12 6.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3140) Cmyb_C PF09316.10 PRP85976.1 - 0.094 12.4 0.8 0.16 11.6 0.5 1.5 1 1 0 1 1 1 0 C-myb, C-terminal DUF3437 PF11919.8 PRP85976.1 - 0.098 12.6 0.1 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Carboxyl_trans PF01039.22 PRP85977.1 - 1.1e-77 261.8 0.0 2.2e-77 260.8 0.0 1.5 1 0 0 1 1 1 1 Carboxyl transferase domain Pkinase_Tyr PF07714.17 PRP85977.1 - 2.8e-62 210.3 0.0 1.1e-61 208.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase CPSase_L_D2 PF02786.17 PRP85977.1 - 5.3e-53 179.7 0.0 9.4e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain LRR_8 PF13855.6 PRP85977.1 - 1.4e-39 133.7 90.0 1.4e-07 31.2 0.1 13.5 7 4 5 14 14 14 10 Leucine rich repeat Biotin_carb_N PF00289.22 PRP85977.1 - 2.2e-38 131.2 0.0 5.6e-38 129.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Pkinase PF00069.25 PRP85977.1 - 2e-36 125.7 0.0 2.1e-35 122.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP85977.1 - 5.2e-33 112.5 96.2 2.6e-06 27.7 2.2 14.9 11 2 2 15 15 14 10 Leucine Rich repeats (2 copies) Biotin_carb_C PF02785.19 PRP85977.1 - 1.1e-20 73.7 0.0 3.8e-20 72.0 0.0 2.0 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Lip_prot_lig_C PF10437.9 PRP85977.1 - 8.6e-16 57.7 0.0 2.7e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus Biotin_lipoyl PF00364.22 PRP85977.1 - 9.1e-13 47.8 4.0 2.5e-12 46.5 4.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PRP85977.1 - 4.3e-10 39.3 3.6 4e-06 26.5 0.6 3.0 1 1 1 2 2 2 2 Biotin-lipoyl like BPL_LplA_LipB PF03099.19 PRP85977.1 - 1.8e-06 27.9 0.0 5.9e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family LRR_9 PF14580.6 PRP85977.1 - 0.00024 20.7 22.3 0.039 13.5 1.3 5.6 2 2 4 6 6 6 3 Leucine-rich repeat ATP-grasp PF02222.22 PRP85977.1 - 0.00026 20.6 0.0 0.0017 17.9 0.1 2.2 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 PRP85977.1 - 0.0029 16.9 0.0 0.0064 15.8 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 PRP85977.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus LRR_1 PF00560.33 PRP85977.1 - 0.0098 16.3 81.1 1 10.2 0.5 21.2 24 2 0 24 24 18 3 Leucine Rich Repeat ATP-grasp_3 PF02655.14 PRP85977.1 - 0.012 15.7 0.3 0.13 12.3 0.1 2.8 2 1 0 2 2 2 0 ATP-grasp domain HlyD_D23 PF16576.5 PRP85977.1 - 0.028 13.6 3.5 0.16 11.2 0.2 2.9 2 1 1 3 3 3 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion LRR_5 PF13306.6 PRP85977.1 - 0.32 10.9 4.3 0.24 11.4 0.3 2.9 3 0 0 3 3 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 PRP85977.1 - 0.35 11.0 55.4 14 6.1 0.1 16.8 19 0 0 19 19 18 0 Leucine Rich repeat Peptidase_M23 PF01551.22 PRP85977.1 - 0.4 10.9 1.5 3.1 8.1 0.4 2.6 1 1 1 2 2 2 0 Peptidase family M23 ATP-grasp_2 PF08442.10 PRP85977.1 - 5.9 6.4 6.3 6.6 6.2 3.9 2.3 3 0 0 3 3 3 0 ATP-grasp domain ABC_membrane PF00664.23 PRP85978.1 - 5.5e-52 177.1 14.1 7.5e-52 176.7 14.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PRP85978.1 - 3.4e-30 105.4 0.0 8.7e-30 104.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PRP85978.1 - 3.4e-09 36.5 1.2 2.9e-07 30.1 0.1 2.2 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PRP85978.1 - 0.00021 21.5 0.0 0.00088 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PRP85978.1 - 0.0018 18.0 0.1 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PRP85978.1 - 0.0062 15.8 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 PRP85978.1 - 0.0088 16.4 0.1 0.035 14.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 PRP85978.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 PRP85978.1 - 0.014 15.6 0.1 0.065 13.5 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 PRP85978.1 - 0.061 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PRP85978.1 - 0.08 12.9 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 PRP85978.1 - 0.084 13.0 0.0 0.54 10.3 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 PRP85978.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FtsK_gamma PF09397.10 PRP85978.1 - 0.12 12.2 0.6 0.33 10.8 0.1 2.0 2 0 0 2 2 2 0 Ftsk gamma domain NTPase_1 PF03266.15 PRP85978.1 - 0.15 12.0 0.2 5.4 6.9 0.4 2.3 2 0 0 2 2 2 0 NTPase AAA PF00004.29 PRP85978.1 - 0.26 11.7 1.4 5.4 7.5 1.4 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Methyltr_RsmB-F PF01189.17 PRP85979.1 - 2.1e-33 115.7 0.0 3.2e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PRP85979.1 - 0.0043 17.2 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 PRP85979.1 - 0.0045 16.5 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 PRP85979.1 - 0.0055 15.8 0.0 0.025 13.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase NAD_kinase PF01513.21 PRP85980.1 - 1.5e-64 218.0 0.0 3.1e-64 217.0 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 PRP85980.1 - 0.0055 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TPALS PF18178.1 PRP85980.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Insulin_TMD PF17870.1 PRP85981.1 - 0.053 13.6 0.5 0.11 12.6 0.5 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Folate_rec PF03024.14 PRP85982.1 - 5.5e-07 29.6 6.2 1e-06 28.7 6.2 1.4 1 0 0 1 1 1 1 Folate receptor family Fz PF01392.22 PRP85982.1 - 0.015 15.9 6.8 0.015 15.9 6.8 2.2 1 1 2 3 3 3 0 Fz domain fn3 PF00041.21 PRP85983.1 - 1.9e-07 31.3 2.1 0.00046 20.5 0.1 3.7 3 1 0 3 3 3 2 Fibronectin type III domain CinA_KH PF18146.1 PRP85984.1 - 0.13 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain RhoGAP PF00620.27 PRP85985.1 - 5.3e-21 75.0 0.0 1e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Amastin PF07344.11 PRP85987.1 - 1.1 9.1 14.2 0.054 13.3 7.0 2.4 3 0 0 3 3 3 0 Amastin surface glycoprotein IPK PF03770.16 PRP85991.1 - 0.00014 21.8 0.0 0.00019 21.4 0.0 1.3 1 1 0 1 1 1 1 Inositol polyphosphate kinase Spc7 PF08317.11 PRP85993.1 - 0.0034 16.3 23.3 0.0034 16.3 23.3 12.2 2 1 10 12 12 12 7 Spc7 kinetochore protein UPF0242 PF06785.11 PRP85993.1 - 0.0097 16.0 3.5 0.0097 16.0 3.5 14.7 1 1 14 15 15 15 3 Uncharacterised protein family (UPF0242) N-terminus Glutaredoxin PF00462.24 PRP85993.1 - 0.085 13.1 0.7 0.76 10.0 0.7 2.8 1 0 0 1 1 1 0 Glutaredoxin zf-RING_11 PF17123.5 PRP85994.1 - 0.026 14.3 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 PRP85994.1 - 0.13 12.6 0.2 0.21 12.0 0.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C2H2 PF00096.26 PRP85995.1 - 0.003 17.9 2.3 0.83 10.2 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 PRP85995.1 - 0.0062 16.8 1.3 0.75 10.2 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PRP85995.1 - 0.025 15.4 1.9 5.5 8.1 0.2 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M41 PF01434.18 PRP85996.1 - 2.8e-60 203.5 0.1 4.9e-60 202.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 TRM13 PF05206.14 PRP85996.1 - 2.7e-50 171.4 1.9 2.7e-50 171.4 1.9 3.3 3 1 0 3 3 3 1 Methyltransferase TRM13 AAA PF00004.29 PRP85996.1 - 1e-40 139.2 0.0 2.3e-40 138.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP85996.1 - 8.6e-12 44.7 0.0 2.3e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 PRP85996.1 - 9e-07 29.2 0.2 4.8e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 FtsH Extracellular zf-TRM13_CCCH PF11722.8 PRP85996.1 - 1.1e-05 25.1 1.2 3e-05 23.7 1.2 1.8 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein AAA_22 PF13401.6 PRP85996.1 - 0.0002 21.7 0.0 0.38 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Methyltransf_32 PF13679.6 PRP85996.1 - 0.00027 21.0 2.8 0.00027 21.0 2.8 2.3 3 0 0 3 3 2 1 Methyltransferase domain AAA_5 PF07728.14 PRP85996.1 - 0.00067 19.7 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP85996.1 - 0.011 16.1 0.3 0.12 12.8 0.1 2.5 1 1 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 PRP85996.1 - 0.017 15.2 0.0 0.075 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PRP85996.1 - 0.018 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 PRP85996.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 PRP85996.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Presenilin PF01080.17 PRP85996.1 - 2.4 6.8 7.1 0.93 8.2 0.1 2.3 2 0 0 2 2 2 0 Presenilin Ribosomal_L27e PF01777.18 PRP85997.1 - 1.4e-28 99.1 1.7 2.2e-28 98.4 1.7 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 PRP85997.1 - 7.8e-05 22.5 3.2 0.00013 21.8 1.9 2.0 3 0 0 3 3 3 1 KOW motif JAB PF01398.21 PRP85998.1 - 6.8e-17 61.5 0.0 1.4e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Fib_alpha PF08702.10 PRP85998.1 - 0.12 12.6 3.0 1.6 8.9 0.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TPR_11 PF13414.6 PRP85999.1 - 1.6e-13 50.1 9.4 0.00033 20.3 0.1 5.1 4 1 1 5 5 5 4 TPR repeat TPR_19 PF14559.6 PRP85999.1 - 5.1e-10 39.7 11.3 0.00081 19.8 0.4 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP85999.1 - 9.5e-09 34.7 21.4 1.2e-05 25.1 0.9 6.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP85999.1 - 3.6e-07 30.7 13.1 0.0011 19.6 0.2 4.4 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP85999.1 - 3.3e-06 27.1 7.1 0.059 13.8 0.3 4.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP85999.1 - 1.1e-05 25.0 11.0 0.00026 20.7 0.4 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP85999.1 - 8.4e-05 22.8 9.2 9.3e-05 22.7 0.3 4.2 2 2 3 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP85999.1 - 0.0001 22.5 5.9 0.0059 16.8 0.4 3.4 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PRP85999.1 - 0.00028 21.4 11.1 1.7 9.7 0.6 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat TOM20_plant PF06552.12 PRP85999.1 - 0.00032 20.5 4.5 0.021 14.6 0.7 2.9 1 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_7 PF13176.6 PRP85999.1 - 0.0012 18.7 2.4 0.12 12.5 0.1 4.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 PRP85999.1 - 0.0023 17.7 0.3 0.0023 17.7 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 PRP85999.1 - 0.0069 16.2 2.2 0.035 14.0 0.0 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP85999.1 - 0.01 16.0 14.2 0.027 14.7 0.1 5.9 6 2 1 7 7 6 0 Tetratricopeptide repeat DUF2989 PF11207.8 PRP85999.1 - 0.042 13.6 3.3 0.066 13.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) TPR_6 PF13174.6 PRP85999.1 - 0.37 11.5 7.1 2.9 8.7 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat WD40 PF00400.32 PRP86000.1 - 5.1e-40 134.7 10.6 6.3e-10 39.5 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Katanin_con80 PF13925.6 PRP86000.1 - 1.6e-37 129.0 0.2 2.3e-37 128.5 0.2 1.3 1 0 0 1 1 1 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 PRP86000.1 - 1.6e-15 57.1 0.0 0.00047 20.4 0.0 5.4 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP86000.1 - 2.5e-07 30.8 0.0 0.036 13.9 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PRP86000.1 - 0.02 13.9 0.2 2.5 7.0 0.0 3.5 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4550 PF15084.6 PRP86000.1 - 0.031 14.7 0.2 3.8 8.0 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4550) Vps35 PF03635.17 PRP86000.1 - 0.18 10.3 0.1 0.24 9.9 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 AAA_16 PF13191.6 PRP86001.1 - 3.7e-09 37.2 0.1 5.9e-09 36.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PRP86001.1 - 2.6e-07 31.0 0.3 9.2e-07 29.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 PRP86001.1 - 1.2e-05 25.7 0.0 3.9e-05 24.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 PRP86001.1 - 9.5e-05 22.4 0.0 0.00017 21.6 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 PRP86001.1 - 0.00058 19.8 0.1 0.0011 19.0 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Cdc6_C PF09079.11 PRP86001.1 - 0.0033 17.4 0.3 0.011 15.7 0.1 2.0 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain DUF2075 PF09848.9 PRP86001.1 - 0.0055 16.0 0.0 0.0096 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_lid_10 PF17872.1 PRP86001.1 - 0.0078 16.3 0.1 0.045 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA lid domain AAA_19 PF13245.6 PRP86001.1 - 0.0081 16.5 0.0 0.024 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP86001.1 - 0.0085 15.4 0.0 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 PRP86001.1 - 0.014 15.7 0.0 0.075 13.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Microtub_bd PF16796.5 PRP86001.1 - 0.017 15.0 0.1 0.043 13.8 0.1 1.7 1 0 0 1 1 1 0 Microtubule binding AKAP2_C PF15304.6 PRP86001.1 - 0.018 14.4 3.3 0.029 13.7 3.3 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Kinesin PF00225.23 PRP86001.1 - 0.026 13.4 0.1 0.037 12.9 0.1 1.3 1 0 0 1 1 1 0 Kinesin motor domain NB-ARC PF00931.22 PRP86001.1 - 0.041 13.0 0.0 0.081 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 PRP86001.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NTPase KTI12 PF08433.10 PRP86001.1 - 0.048 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.23 PRP86001.1 - 0.053 13.6 0.1 0.56 10.3 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 PRP86001.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 PRP86001.1 - 0.072 12.3 0.4 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain MeaB PF03308.16 PRP86001.1 - 0.077 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 PRP86001.1 - 0.084 12.9 0.1 0.32 11.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP86001.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PRP86001.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region COX4 PF02936.14 PRP86002.1 - 0.067 13.2 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV RAMP4 PF06624.12 PRP86003.1 - 1.5e-19 69.8 0.6 1.6e-19 69.7 0.6 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF1206 PF06724.11 PRP86003.1 - 0.027 14.6 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) NMO PF03060.15 PRP86004.1 - 2.7e-65 220.9 0.0 3.5e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 PRP86004.1 - 3.2e-07 29.7 0.0 1.8e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 PRP86004.1 - 0.00049 19.4 0.1 0.0008 18.7 0.1 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 PRP86004.1 - 0.00064 18.8 0.3 0.0014 17.8 0.1 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 PRP86004.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein Glu_synthase PF01645.17 PRP86004.1 - 0.041 13.0 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase G3P_antiterm PF04309.12 PRP86004.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Nucleoporin_FG PF13634.6 PRP86005.1 - 3.1e-15 56.8 264.3 5e-07 30.5 31.0 12.0 2 2 6 8 8 8 4 Nucleoporin FG repeat region DUF745 PF05335.13 PRP86005.1 - 0.094 12.4 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) cNMP_binding PF00027.29 PRP86006.1 - 2.4e-21 75.6 0.1 2e-12 47.0 0.1 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 PRP86006.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Helicase_PWI PF18149.1 PRP86006.1 - 0.075 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal helicase PWI domain OTU PF02338.19 PRP86007.1 - 9.1e-09 35.9 2.1 2.1e-08 34.7 0.0 2.6 4 0 0 4 4 4 1 OTU-like cysteine protease PKcGMP_CC PF16808.5 PRP86007.1 - 1 9.2 7.1 0.26 11.2 0.3 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Lebercilin PF15619.6 PRP86007.1 - 2.4 7.7 16.8 3.5 7.3 0.6 2.8 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Pkinase_Tyr PF07714.17 PRP86008.1 - 4.4e-27 95.0 0.3 6.4e-27 94.5 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PRP86008.1 - 1.4e-25 88.9 36.2 3e-06 27.5 0.5 8.6 7 1 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP86008.1 - 1.6e-21 75.8 34.0 3.4e-06 26.7 0.0 7.6 5 2 4 9 9 9 8 Leucine rich repeat Pkinase PF00069.25 PRP86008.1 - 3.8e-18 65.8 0.1 6e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP86008.1 - 1.3e-08 35.3 3.6 2.9e-08 34.1 3.6 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP86008.1 - 7.1e-07 28.9 26.7 2.6 8.9 0.1 9.3 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP86008.1 - 0.64 10.2 32.4 2.4 8.4 0.1 9.6 10 0 0 10 10 10 0 Leucine Rich repeat TMEM154 PF15102.6 PRP86008.1 - 2.1 8.2 6.2 0.35 10.8 0.3 2.3 2 0 0 2 2 2 0 TMEM154 protein family PI3_PI4_kinase PF00454.27 PRP86009.1 - 1.6e-50 172.2 0.5 3.4e-50 171.2 0.5 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 PRP86009.1 - 2.4e-33 115.8 2.8 2.4e-33 115.8 2.8 2.3 2 1 0 2 2 2 1 FAT domain UME PF08064.13 PRP86009.1 - 4.4e-13 49.0 0.3 9.9e-12 44.7 0.0 3.7 2 1 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 PRP86009.1 - 6.7e-10 38.6 0.7 5.6e-09 35.7 0.4 2.5 2 0 0 2 2 2 1 FATC domain Anticodon_1 PF08264.13 PRP86009.1 - 0.0059 16.6 0.2 0.025 14.5 0.1 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA L27_1 PF09058.10 PRP86009.1 - 0.01 15.8 2.8 0.32 11.0 0.3 4.3 4 0 0 4 4 4 0 L27_1 SF3A3 PF16837.5 PRP86009.1 - 0.16 12.5 1.0 1.2 9.7 0.1 3.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 IFS PF16718.5 PRP86009.1 - 0.19 11.8 1.8 2.3 8.3 0.3 3.0 2 0 0 2 2 2 0 Immunity factor for SPN Pkinase_Tyr PF07714.17 PRP86010.1 - 4.4e-80 268.7 0.0 6.1e-80 268.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86010.1 - 5e-54 183.4 0.0 7.6e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP86010.1 - 3.5e-35 119.5 70.3 2.5e-07 30.3 6.3 11.6 7 3 3 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 PRP86010.1 - 8.4e-25 86.4 75.2 0.0001 22.6 7.0 12.9 10 2 4 15 15 15 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP86010.1 - 3.6e-05 23.5 60.1 2.3 8.5 0.1 16.1 17 0 0 17 17 17 2 Leucine Rich repeat LRR_1 PF00560.33 PRP86010.1 - 0.00025 21.2 86.0 0.68 10.7 0.9 18.9 22 1 0 22 22 22 4 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP86010.1 - 0.0051 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP86010.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 PRP86010.1 - 0.045 13.7 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP86010.1 - 0.052 12.5 0.0 0.12 11.3 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Nucleoporin_FG PF13634.6 PRP86011.1 - 7.4e-07 29.9 52.6 8.4e-06 26.6 14.5 5.5 2 2 3 5 5 5 2 Nucleoporin FG repeat region LOH1CR12 PF10158.9 PRP86011.1 - 0.024 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor protein FapA PF03961.13 PRP86011.1 - 0.18 10.4 0.3 5.4 5.5 0.0 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Syntaxin-6_N PF09177.11 PRP86011.1 - 0.21 12.2 1.9 0.33 11.5 0.3 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Mod_r PF07200.13 PRP86011.1 - 0.33 11.1 3.0 0.52 10.4 3.0 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FLYWCH PF04500.16 PRP86012.1 - 0.0013 18.8 1.3 0.0024 17.9 1.3 1.4 1 0 0 1 1 1 1 FLYWCH zinc finger domain NmrA PF05368.13 PRP86013.1 - 9.4e-11 41.7 0.4 0.00013 21.7 0.1 2.4 1 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 PRP86013.1 - 0.0032 17.4 0.2 0.85 9.5 0.1 2.2 1 1 1 2 2 2 2 NAD(P)H-binding F-box PF00646.33 PRP86014.1 - 0.00014 21.7 0.3 0.00042 20.1 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP86014.1 - 0.0026 17.6 0.6 0.0082 16.0 0.6 1.9 1 0 0 1 1 1 1 F-box Ank_4 PF13637.6 PRP86014.1 - 0.098 13.3 0.0 1.2e+02 3.5 0.0 4.6 5 0 0 5 5 5 0 Ankyrin repeats (many copies) DNA_mis_repair PF01119.19 PRP86015.1 - 1.4e-15 57.0 0.1 7.4e-15 54.7 0.1 2.1 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 PRP86015.1 - 1.8e-10 40.7 0.0 4e-08 33.2 0.0 2.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain SH2 PF00017.24 PRP86015.1 - 2.3e-10 40.4 0.0 6.4e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HATPase_c_3 PF13589.6 PRP86015.1 - 6.4e-09 35.8 0.0 1.4e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VPS9 PF02204.18 PRP86015.1 - 2.9e-08 33.8 0.1 8e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain HATPase_c PF02518.26 PRP86015.1 - 8.2e-07 29.5 0.0 2.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CUE PF02845.16 PRP86015.1 - 3.1e-05 23.6 0.0 0.00012 21.7 0.0 2.0 2 0 0 2 2 2 1 CUE domain CODH_A_N PF18537.1 PRP86015.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain LRR_9 PF14580.6 PRP86016.1 - 2.3e-77 258.4 44.8 3.8e-19 68.9 2.4 7.6 3 3 3 6 6 6 6 Leucine-rich repeat LRR_4 PF12799.7 PRP86016.1 - 1.6e-64 212.7 107.7 6.3e-08 32.8 3.0 16.0 10 4 4 17 17 17 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP86016.1 - 1.2e-44 149.9 95.1 3.1e-10 39.6 4.6 11.7 8 3 4 12 12 12 11 Leucine rich repeat PARP PF00644.20 PRP86016.1 - 0.015 14.9 0.9 4.5 6.8 0.0 3.3 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase catalytic domain LRR_2 PF07723.13 PRP86016.1 - 0.16 12.7 9.1 2.4 9.0 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat F-box PF00646.33 PRP86017.1 - 0.0067 16.3 1.0 0.0085 15.9 0.1 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP86017.1 - 0.1 12.5 0.4 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 F-box-like Ank_2 PF12796.7 PRP86018.1 - 7.4e-38 129.0 0.0 1.6e-09 38.2 0.0 5.2 4 1 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP86018.1 - 2.1e-35 120.7 5.2 2.2e-06 28.1 0.0 8.2 2 2 7 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 PRP86018.1 - 1.5e-28 98.0 4.2 0.034 14.6 0.0 10.6 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 PRP86018.1 - 4.1e-23 81.1 0.4 0.096 13.0 0.0 9.7 3 2 7 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP86018.1 - 1.4e-16 58.9 0.8 3 8.7 0.0 10.0 11 0 0 11 11 11 3 Ankyrin repeat Secretogranin_V PF05281.11 PRP86018.1 - 7.7e-06 25.7 0.5 1.3 8.6 0.0 3.8 1 1 3 4 4 4 2 Neuroendocrine protein 7B2 precursor (Secretogranin V) DUF3734 PF12536.8 PRP86018.1 - 0.0058 17.0 1.0 6.8 7.1 0.0 4.1 1 1 2 4 4 4 1 Patatin phospholipase DUF1571 PF07608.11 PRP86018.1 - 0.0097 15.4 0.2 1.9 7.9 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1571) Ras PF00071.22 PRP86020.1 - 6.6e-53 178.6 0.0 3.2e-52 176.4 0.0 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP86020.1 - 1.1e-17 64.3 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP86020.1 - 2.6e-09 36.8 0.1 9.3e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP86020.1 - 1.8e-08 34.5 0.1 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP86020.1 - 2.9e-06 27.0 0.0 8.9e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PRP86020.1 - 0.00019 21.0 0.1 0.00054 19.5 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 PRP86020.1 - 0.015 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 PRP86020.1 - 0.016 14.4 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 PRP86020.1 - 0.029 14.8 0.0 0.074 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 PRP86020.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ac76 PF05814.11 PRP86022.1 - 0.16 12.0 1.7 0.65 10.0 1.7 2.1 1 0 0 1 1 1 0 Orf76 (Ac76) SNF2_N PF00176.23 PRP86023.1 - 6.4e-76 255.3 0.0 1e-75 254.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP86023.1 - 1.3e-16 60.9 0.0 1.6e-15 57.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain WW PF00397.26 PRP86023.1 - 8.1e-09 35.4 0.4 1.8e-08 34.3 0.4 1.6 1 0 0 1 1 1 1 WW domain zf-RING_2 PF13639.6 PRP86023.1 - 6.8e-08 32.7 8.3 1.5e-07 31.6 8.3 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 PRP86023.1 - 1.2e-07 31.5 7.7 3e-07 30.2 7.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PRP86023.1 - 1.3e-07 31.3 9.9 2.9e-07 30.2 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP86023.1 - 1.6e-07 31.2 6.8 3.3e-07 30.1 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PRP86023.1 - 6.9e-07 29.0 10.5 1.4e-06 28.1 10.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.11 PRP86023.1 - 1.4e-05 25.0 0.0 3.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-RING_UBOX PF13445.6 PRP86023.1 - 1.8e-05 24.7 3.4 1.8e-05 24.7 3.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PRP86023.1 - 0.00013 21.8 9.3 0.00034 20.4 9.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP86023.1 - 0.00014 22.1 7.1 0.00038 20.7 7.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain DEAD PF00270.29 PRP86023.1 - 0.00024 20.9 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-ANAPC11 PF12861.7 PRP86023.1 - 0.006 16.6 2.2 0.013 15.5 2.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 PRP86023.1 - 0.019 14.6 4.6 0.061 13.0 4.6 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_10 PF16685.5 PRP86023.1 - 0.025 14.7 6.2 0.07 13.3 6.2 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 PRP86023.1 - 0.057 13.4 4.5 0.12 12.4 4.5 1.4 1 0 0 1 1 1 0 zinc-ribbons AAA_34 PF13872.6 PRP86023.1 - 0.16 10.9 0.3 0.53 9.1 0.3 1.7 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-C3HC4_4 PF15227.6 PRP86023.1 - 0.46 10.7 7.2 1.3 9.3 7.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CH PF00307.31 PRP86024.1 - 2.2e-09 37.5 0.0 3.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain MCM PF00493.23 PRP86025.1 - 1.6e-93 311.9 0.0 2.7e-93 311.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PRP86025.1 - 2.4e-35 121.1 0.1 7.1e-35 119.6 0.1 1.8 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PRP86025.1 - 8.5e-27 93.4 0.4 8.5e-27 93.4 0.4 3.2 3 1 1 4 4 4 1 MCM AAA-lid domain MCM_N PF14551.6 PRP86025.1 - 4.8e-17 62.4 2.4 6.9e-17 61.9 0.4 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 PRP86025.1 - 5.6e-08 32.4 0.0 6.5e-07 28.9 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PRP86025.1 - 8.8e-07 29.0 0.0 3.2e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PRP86025.1 - 4.2e-05 23.4 0.1 0.00091 19.1 0.0 3.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 PRP86025.1 - 0.013 15.4 0.2 0.038 13.8 0.2 1.8 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 PRP86025.1 - 0.028 14.1 0.1 0.18 11.5 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 PRP86025.1 - 0.05 14.0 0.0 0.21 12.0 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_5 PF05631.14 PRP86026.1 - 3.2e-107 358.5 14.7 5.7e-107 357.7 14.7 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Amino_oxidase PF01593.24 PRP86026.1 - 3.2e-70 237.7 0.0 4.4e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase UPF0060 PF02694.15 PRP86026.1 - 6.7e-37 126.0 9.3 6.7e-37 126.0 9.3 2.4 2 0 0 2 2 2 1 Uncharacterised BCR, YnfA/UPF0060 family MFS_1 PF07690.16 PRP86026.1 - 7.8e-28 97.4 59.1 2e-23 82.9 28.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_8 PF13450.6 PRP86026.1 - 7.1e-13 48.6 0.1 2e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP86026.1 - 3.8e-07 30.0 0.4 8.7e-07 28.8 0.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Sugar_tr PF00083.24 PRP86026.1 - 9.6e-07 28.0 11.7 9.6e-07 28.0 11.7 3.5 2 1 1 3 3 2 1 Sugar (and other) transporter Pyr_redox_3 PF13738.6 PRP86026.1 - 4.5e-06 26.1 0.2 0.041 13.1 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP86026.1 - 2.6e-05 23.5 0.3 4.7e-05 22.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 PRP86026.1 - 0.00088 18.6 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP86026.1 - 0.0027 17.0 0.1 0.0052 16.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP86026.1 - 0.0064 16.5 0.1 0.21 11.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 PRP86026.1 - 0.015 14.5 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 PRP86026.1 - 0.02 15.4 0.3 0.081 13.5 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 PRP86026.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase DUF4044 PF13253.6 PRP86026.1 - 0.048 13.2 2.3 0.26 10.8 2.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) HI0933_like PF03486.14 PRP86026.1 - 0.058 12.1 0.1 0.19 10.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 PRP86026.1 - 0.23 10.8 0.4 0.37 10.1 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 PRP86026.1 - 0.24 10.4 0.2 1 8.3 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF5383 PF17355.2 PRP86026.1 - 0.34 11.3 2.7 42 4.5 0.0 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5383) LSM PF01423.22 PRP86027.1 - 2.2e-21 75.3 0.8 3.7e-21 74.6 0.8 1.4 1 0 0 1 1 1 1 LSM domain CENP-T_C PF15511.6 PRP86027.1 - 5.4e-07 29.7 0.2 1.1e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PRP86027.1 - 0.00076 19.8 0.1 0.0019 18.6 0.1 1.6 1 0 0 1 1 1 1 CENP-S protein TAF PF02969.17 PRP86027.1 - 0.0012 19.0 0.2 0.0022 18.1 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 PRP86027.1 - 0.0045 17.2 0.3 0.015 15.5 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PRP86027.1 - 0.0068 16.8 0.2 0.013 15.8 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PRP86027.1 - 0.021 14.9 0.0 0.069 13.2 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 PRP86027.1 - 0.09 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Bromodomain associated LSM PF01423.22 PRP86029.1 - 1e-18 66.7 0.5 1.1e-18 66.6 0.5 1.0 1 0 0 1 1 1 1 LSM domain WRNPLPNID PF15017.6 PRP86030.1 - 0.023 15.6 7.5 0.023 15.6 7.5 3.3 3 1 0 3 3 3 0 Putative WW-binding domain and destruction box Vpu PF00558.19 PRP86030.1 - 0.11 12.2 2.9 0.44 10.3 2.9 2.0 1 0 0 1 1 1 0 Vpu protein DUF4530 PF15039.6 PRP86030.1 - 0.12 12.5 2.8 0.35 11.0 2.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) LSM PF01423.22 PRP86032.1 - 1.8e-16 59.6 0.1 2.3e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PRP86032.1 - 8.4e-05 22.6 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain zf-met2 PF12907.7 PRP86033.1 - 6.4e-09 35.8 2.0 9e-09 35.3 2.0 1.2 1 0 0 1 1 1 1 Zinc-binding zf-C2H2_8 PF15909.5 PRP86033.1 - 0.03 14.6 0.1 0.034 14.4 0.1 1.2 1 0 0 1 1 1 0 C2H2-type zinc ribbon Katanin_con80 PF13925.6 PRP86033.1 - 0.036 14.1 0.6 0.044 13.8 0.6 1.0 1 0 0 1 1 1 0 con80 domain of Katanin TagA PF12561.8 PRP86033.1 - 0.1 13.0 0.1 0.13 12.7 0.1 1.1 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain Ank_4 PF13637.6 PRP86035.1 - 2.5e-09 37.5 0.0 0.0017 18.9 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86035.1 - 3.6e-09 37.1 0.0 1.4e-07 32.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP86035.1 - 2.7e-05 24.3 0.0 0.42 11.0 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP86035.1 - 5.7e-05 23.4 0.0 0.69 10.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP86035.1 - 0.067 13.8 0.0 49 5.0 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Amidohydro_3 PF07969.11 PRP86035.1 - 0.17 11.3 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family DUF1179 PF06678.11 PRP86036.1 - 0.16 11.9 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) zf-MIZ PF02891.20 PRP86037.1 - 6.2e-20 70.7 1.0 1.2e-19 69.8 1.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 PRP86037.1 - 9.2e-06 25.4 3.2 2.2e-05 24.2 3.2 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PaO PF08417.12 PRP86037.1 - 0.087 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Pheophorbide a oxygenase Zmiz1_N PF18028.1 PRP86037.1 - 0.097 13.0 0.1 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain GlgX_C PF18390.1 PRP86037.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain TMEM100 PF16311.5 PRP86038.1 - 0.054 13.1 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 HEPN_Swt1 PF18731.1 PRP86039.1 - 2.4e-20 73.0 0.1 3.2e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 Swt1-like HEPN DUF4145 PF13643.6 PRP86039.1 - 0.0086 16.2 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4145) DUF4559 PF15112.6 PRP86039.1 - 0.059 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Elong_Iki1 PF10483.9 PRP86040.1 - 6.3e-15 55.5 3.3 3.1e-08 33.5 2.1 2.4 1 1 1 2 2 2 2 Elongator subunit Iki1 Phage_TAC_14 PF16462.5 PRP86040.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC AAA_25 PF13481.6 PRP86040.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Yos9_DD PF17880.1 PRP86040.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Yos9 dimerzation domain DHR-2 PF06920.13 PRP86041.1 - 2.4e-59 201.4 4.2 1.5e-58 198.8 4.2 2.3 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 PRP86041.1 - 4e-28 98.5 0.4 4e-28 98.5 0.4 2.9 4 0 0 4 4 4 1 C2 domain in Dock180 and Zizimin proteins DOCK_N PF16172.5 PRP86041.1 - 4.7e-25 88.3 0.0 1.7e-22 79.9 0.0 3.0 2 0 0 2 2 2 2 DOCK N-terminus SH3_9 PF14604.6 PRP86041.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP86041.1 - 0.00035 20.1 0.0 0.00082 18.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain LMBR1 PF04791.16 PRP86042.1 - 4.4e-39 134.8 42.0 3.9e-24 85.5 16.4 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein Ank_2 PF12796.7 PRP86042.1 - 2.4e-07 31.2 0.0 0.0012 19.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 PRP86042.1 - 0.00011 22.5 1.4 0.091 13.2 0.0 4.2 2 1 1 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 PRP86042.1 - 0.0002 21.6 0.1 12 6.3 0.0 4.6 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP86042.1 - 0.00022 21.7 0.1 1.6 9.4 0.0 4.1 3 1 1 4 4 4 1 Ankyrin repeats (many copies) RAMP4 PF06624.12 PRP86042.1 - 4.2 7.5 6.7 25 5.0 3.5 3.4 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 Methyltransf_16 PF10294.9 PRP86043.1 - 2.4e-22 79.5 0.1 2.9e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 PRP86043.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NYD-SP28_assoc PF14775.6 PRP86043.1 - 0.014 15.5 0.7 0.044 13.9 0.1 2.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Cons_hypoth95 PF03602.15 PRP86043.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CAP PF00188.26 PRP86044.1 - 1.6e-19 71.0 6.6 4e-19 69.7 6.6 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PT PF04886.12 PRP86044.1 - 0.038 13.5 31.0 0.024 14.2 5.9 4.3 2 1 1 3 3 3 0 PT repeat Auxin_resp PF06507.13 PRP86044.1 - 0.052 13.8 0.5 0.64 10.3 0.0 2.4 2 0 0 2 2 2 0 Auxin response factor DUF3792 PF12670.7 PRP86045.1 - 0.31 11.2 6.7 0.057 13.6 2.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Laminin_EGF PF00053.24 PRP86047.1 - 0.034 14.3 11.8 0.067 13.3 11.8 1.4 1 0 0 1 1 1 0 Laminin EGF domain EGF_2 PF07974.13 PRP86047.1 - 0.046 14.1 18.0 0.1 13.0 18.0 1.6 1 0 0 1 1 1 0 EGF-like domain SOG2 PF10428.9 PRP86047.1 - 0.41 9.8 11.2 0.58 9.3 11.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM223 PF14640.6 PRP86047.1 - 0.45 10.7 4.6 1.1 9.5 2.1 2.7 2 1 0 2 2 2 0 Transmembrane protein 223 Hamartin PF04388.12 PRP86047.1 - 1.9 7.1 9.9 2.7 6.6 9.9 1.2 1 0 0 1 1 1 0 Hamartin protein MGC-24 PF05283.11 PRP86047.1 - 2.6 8.5 19.3 0.68 10.4 9.6 2.3 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5408 PF17402.2 PRP86048.1 - 0.00071 19.4 0.1 0.003 17.4 0.0 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5408) Prefoldin_2 PF01920.20 PRP86048.1 - 0.15 12.0 4.5 0.22 11.5 4.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit HMG_CoA_synt_C PF08540.10 PRP86049.1 - 1.3e-90 303.8 9.6 1.9e-90 303.3 9.6 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 PRP86049.1 - 1.4e-82 275.8 0.2 2.3e-82 275.1 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Ank_4 PF13637.6 PRP86049.1 - 3.7e-11 43.3 0.0 0.33 11.6 0.0 5.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86049.1 - 6.2e-09 36.3 0.0 0.0026 18.3 0.0 4.2 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) DUF4205 PF13898.6 PRP86049.1 - 0.014 14.3 0.1 0.033 13.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4205) IL1_propep PF02394.16 PRP86049.1 - 0.022 15.7 3.9 0.24 12.3 0.3 2.7 2 0 0 2 2 2 0 Interleukin-1 propeptide Ank PF00023.30 PRP86049.1 - 0.04 14.4 0.2 21 5.8 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat CH PF00307.31 PRP86050.1 - 3.1e-11 43.4 0.5 2.1e-09 37.5 0.1 2.8 3 0 0 3 3 3 1 Calponin homology (CH) domain PH PF00169.29 PRP86050.1 - 0.078 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 PH domain Prefoldin_2 PF01920.20 PRP86053.1 - 2e-19 69.5 12.9 2e-19 69.5 12.9 1.6 1 1 1 2 2 2 1 Prefoldin subunit Rh5 PF18515.1 PRP86053.1 - 0.0032 16.8 4.7 0.0039 16.5 4.7 1.2 1 0 0 1 1 1 1 Rh5 coiled-coil domain Rx_N PF18052.1 PRP86053.1 - 0.0078 16.5 1.1 0.0078 16.5 1.1 2.0 2 1 0 2 2 2 1 Rx N-terminal domain Prefoldin PF02996.17 PRP86053.1 - 0.016 15.1 10.8 1.5 8.8 10.8 2.3 1 1 0 1 1 1 0 Prefoldin subunit XhlA PF10779.9 PRP86053.1 - 0.023 14.9 4.6 0.023 14.9 4.6 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF948 PF06103.11 PRP86053.1 - 0.027 14.7 6.0 0.29 11.4 0.2 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Plant_NMP1 PF06694.11 PRP86053.1 - 0.027 13.6 1.5 0.027 13.6 1.5 1.9 2 0 0 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) Vasculin PF15337.6 PRP86053.1 - 0.035 14.9 0.2 0.035 14.9 0.2 1.9 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 GAS PF13851.6 PRP86053.1 - 0.072 12.4 18.0 0.8 9.0 4.4 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 PRP86053.1 - 0.089 11.7 16.4 0.14 11.1 16.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein SOGA PF11365.8 PRP86053.1 - 0.23 12.6 8.5 0.48 11.6 0.4 2.3 2 1 0 2 2 2 0 Protein SOGA Tup_N PF08581.10 PRP86053.1 - 0.25 11.7 11.4 1.4 9.3 3.5 2.9 2 1 1 3 3 3 0 Tup N-terminal HIP1_clath_bdg PF16515.5 PRP86053.1 - 0.39 11.4 13.3 1.6 9.4 5.1 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Lebercilin PF15619.6 PRP86053.1 - 0.4 10.3 16.6 0.54 9.9 2.2 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Porph_ging PF09697.10 PRP86053.1 - 0.56 10.8 3.6 2.3 8.8 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) DUF4795 PF16043.5 PRP86053.1 - 0.6 9.7 15.9 0.15 11.6 8.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) PocR PF10114.9 PRP86053.1 - 0.92 9.3 4.3 1.3 8.8 0.6 2.0 2 0 0 2 2 2 0 Sensory domain found in PocR Spc24 PF08286.11 PRP86053.1 - 1.5 9.1 13.1 5.9 7.2 6.0 2.4 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 Prominin PF05478.11 PRP86053.1 - 1.8 6.5 8.4 2.1 6.2 8.4 1.1 1 0 0 1 1 1 0 Prominin Seryl_tRNA_N PF02403.22 PRP86053.1 - 2.8 8.2 15.6 2.4 8.4 1.4 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 PRP86053.1 - 2.9 7.2 8.0 3.3 7.0 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 PRP86053.1 - 3.1 7.9 8.8 1.4 8.9 3.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 PRP86053.1 - 3.5 8.1 10.0 0.8 10.1 2.9 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 PRP86053.1 - 5 7.7 9.2 15 6.1 1.9 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_23 PF13476.6 PRP86053.1 - 9.2 6.7 16.4 12 6.4 16.4 1.2 1 0 0 1 1 1 0 AAA domain Pterin_4a PF01329.19 PRP86054.1 - 5.1e-31 106.7 1.0 5.6e-31 106.6 1.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Biopterin_H PF00351.21 PRP86054.1 - 0.0047 16.0 0.1 0.005 15.9 0.1 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ADH_zinc_N PF00107.26 PRP86056.1 - 1.1e-08 35.1 0.1 1.8e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP86056.1 - 2.4e-07 30.6 0.0 9.8e-07 28.6 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PRP86056.1 - 0.0013 19.8 0.0 0.0029 18.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Serpin PF00079.20 PRP86058.1 - 8.1e-53 180.0 0.0 1.6e-52 179.1 0.0 1.5 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) DUF155 PF02582.14 PRP86058.1 - 1.5e-40 139.2 2.0 1e-39 136.5 0.6 2.5 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 RRM_1 PF00076.22 PRP86058.1 - 3.8e-18 65.1 0.0 1.1e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP86058.1 - 0.002 18.2 0.0 0.0061 16.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif Csm1_B PF18211.1 PRP86058.1 - 0.072 12.9 0.0 22 5.0 0.0 2.7 2 0 0 2 2 2 0 Csm1 subunit domain B DUF2973 PF11189.8 PRP86061.1 - 0.016 15.3 0.1 0.047 13.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) DUF2868 PF11067.8 PRP86061.1 - 0.044 13.3 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) RRM_1 PF00076.22 PRP86062.1 - 3.1e-18 65.3 0.1 6.5e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PRP86062.1 - 6.4e-16 58.3 5.5 3.2e-09 36.7 0.1 3.0 2 1 0 2 2 2 2 RNA binding motif DUF3629 PF12302.8 PRP86062.1 - 0.0032 17.0 3.3 0.0055 16.2 3.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3629) RRM_occluded PF16842.5 PRP86062.1 - 0.046 13.6 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Coatamer_beta_C PF07718.12 PRP86062.1 - 1.5 8.7 6.1 4.7 7.1 0.2 3.6 4 1 0 4 4 4 0 Coatomer beta C-terminal region RRM_1 PF00076.22 PRP86064.1 - 4.3e-27 93.7 0.0 1e-09 38.0 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 PRP86064.1 - 0.016 15.4 0.0 0.043 14.0 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif 2 DUF2205 PF10224.9 PRP86064.1 - 0.02 14.9 4.5 0.046 13.7 4.5 1.6 1 0 0 1 1 1 0 Short coiled-coil protein DUF4471 PF14740.6 PRP86064.1 - 0.66 9.1 6.3 1.2 8.3 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF4200 PF13863.6 PRP86064.1 - 1.1 9.7 11.8 2 8.8 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Vfa1 PF08432.10 PRP86064.1 - 1.4 9.2 16.4 2.7 8.3 16.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CCDC53 PF10152.9 PRP86064.1 - 2.7 8.4 14.9 1.9 8.9 7.5 2.4 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Corazonin PF17308.2 PRP86064.1 - 4.1 7.8 9.0 1 9.7 3.9 2.1 2 0 0 2 2 2 0 Pro-corazonin PIEZO PF15917.5 PRP86064.1 - 9.2 5.7 9.2 18 4.7 9.2 1.4 1 0 0 1 1 1 0 Piezo DUF2254 PF10011.9 PRP86065.1 - 1.7e-12 46.8 2.9 2.4e-12 46.4 2.9 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) PapD-like PF14874.6 PRP86066.1 - 9.5e-16 57.8 0.0 2e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like ASH PF15780.5 PRP86066.1 - 0.0041 17.3 0.4 0.019 15.2 0.0 2.4 3 0 0 3 3 3 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 PRP86066.1 - 0.065 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) TFIIA PF03153.13 PRP86066.1 - 0.1 12.6 21.4 0.33 10.9 4.2 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TFIIS_M PF07500.14 PRP86067.1 - 0.00075 20.0 0.6 0.00086 19.8 0.6 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain CENP-H PF05837.12 PRP86067.1 - 0.02 15.3 0.6 0.024 15.0 0.6 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) MCC-bdg_PDZ PF10506.9 PRP86067.1 - 0.059 13.4 0.3 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_1 PF00170.21 PRP86067.1 - 0.067 13.3 0.6 0.38 10.9 0.0 2.2 2 1 1 3 3 3 0 bZIP transcription factor Prominin PF05478.11 PRP86067.1 - 0.068 11.1 0.8 0.074 11.0 0.8 1.0 1 0 0 1 1 1 0 Prominin DHC PF09626.10 PRP86067.1 - 0.074 13.9 0.1 0.085 13.7 0.1 1.2 1 0 0 1 1 1 0 Dihaem cytochrome c RasGEF PF00617.19 PRP86068.1 - 1.4e-52 178.4 1.3 3.2e-52 177.3 1.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP86068.1 - 5.3e-23 81.3 1.7 8e-23 80.7 0.3 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif V_ATPase_I PF01496.19 PRP86069.1 - 0 1016.3 6.0 0 1014.7 6.0 1.6 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 PRP86069.1 - 0.011 15.1 3.8 0.047 13.0 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 PRP86069.1 - 0.025 14.6 5.9 0.64 10.0 2.4 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 PRP86069.1 - 0.06 13.6 1.9 0.62 10.3 0.9 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 PRP86069.1 - 0.14 11.4 10.1 0.93 8.8 5.8 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Occludin_ELL PF07303.13 PRP86069.1 - 0.15 12.8 6.3 4.8 8.0 2.1 3.2 3 0 0 3 3 3 0 Occludin homology domain DUF3782 PF12644.7 PRP86069.1 - 0.2 11.8 1.7 0.97 9.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DUF2408 PF10303.9 PRP86069.1 - 0.38 11.3 8.7 0.36 11.4 6.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Exonuc_VII_L PF02601.15 PRP86069.1 - 0.55 9.8 3.6 2.4 7.6 2.5 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit HSBP1 PF06825.12 PRP86069.1 - 0.71 9.8 5.0 1.6 8.6 0.8 3.1 3 0 0 3 3 3 0 Heat shock factor binding protein 1 zf-C4H2 PF10146.9 PRP86069.1 - 0.99 9.7 6.1 19 5.5 5.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Spore_III_AB PF09548.10 PRP86069.1 - 1.1 9.4 3.9 2.7 8.1 3.9 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Sec34 PF04136.15 PRP86069.1 - 1.1 9.1 11.5 0.21 11.4 4.9 2.8 2 1 1 3 3 3 0 Sec34-like family DASH_Dam1 PF08653.10 PRP86069.1 - 3 7.7 7.1 14 5.6 1.9 3.5 3 0 0 3 3 3 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 PRP86069.1 - 3.9 8.0 6.2 4.8 7.7 1.6 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein EGF_2 PF07974.13 PRP86070.1 - 8.5e-06 26.0 107.7 0.052 13.9 13.8 6.4 6 1 1 7 7 7 4 EGF-like domain DUF4064 PF13273.6 PRP86070.1 - 0.0071 16.6 1.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) Romo1 PF10247.9 PRP86070.1 - 0.034 14.5 1.1 0.077 13.4 1.1 1.6 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Syndecan PF01034.20 PRP86070.1 - 0.1 12.5 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 Syndecan domain BUD22 PF09073.10 PRP86070.1 - 0.53 9.6 30.6 0.008 15.6 22.2 1.9 2 0 0 2 2 2 0 BUD22 Gly-zipper_Omp PF13488.6 PRP86070.1 - 1.4 9.0 7.2 3 7.9 7.2 1.5 1 0 0 1 1 1 0 Glycine zipper CDC27 PF09507.10 PRP86070.1 - 5.5 6.3 35.5 0.059 12.8 23.5 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 FUSC PF04632.12 PRP86072.1 - 7.2e-17 61.2 0.7 7.2e-17 61.2 0.7 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 PRP86072.1 - 1.1e-14 54.6 15.3 1.1e-14 54.6 15.3 4.1 3 1 1 4 4 4 2 Fusaric acid resistance protein-like ALMT PF11744.8 PRP86072.1 - 4.1e-07 29.2 7.3 4.1e-07 29.2 7.3 2.5 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 PRP86072.1 - 0.001 19.0 0.3 0.0038 17.1 0.2 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 PsbN PF02468.15 PRP86072.1 - 0.003 17.4 2.6 2.9 7.8 0.1 3.4 2 0 0 2 2 2 2 Photosystem II reaction centre N protein (psbN) ArAE_2_N PF10337.9 PRP86072.1 - 0.0034 16.5 0.8 0.0034 16.5 0.8 3.2 4 0 0 4 4 4 2 Putative ER transporter, 6TM, N-terminal CYTH PF01928.21 PRP86073.1 - 2.6e-05 24.2 0.0 3.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 CYTH domain DAGAT PF03982.13 PRP86074.1 - 1.4e-97 326.2 0.0 1.9e-97 325.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MCM PF00493.23 PRP86075.1 - 1.4e-87 292.5 0.0 2.2e-87 291.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PRP86075.1 - 1.1e-27 96.3 4.6 2.2e-27 95.4 4.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PRP86075.1 - 2.1e-27 95.3 2.0 4e-27 94.4 2.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PRP86075.1 - 2.8e-10 40.0 0.0 2.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PRP86075.1 - 2e-06 27.9 0.0 4.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PRP86075.1 - 0.00042 20.2 0.0 0.0019 18.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PRP86075.1 - 0.0034 17.1 0.2 0.017 14.8 0.1 2.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 PRP86075.1 - 0.08 13.3 0.4 0.21 12.0 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PRP86075.1 - 0.086 13.3 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP86075.1 - 0.16 12.3 0.1 0.97 9.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain WRKY PF03106.15 PRP86076.1 - 4.5e-34 116.5 18.1 4.8e-18 65.1 11.6 2.8 2 1 1 3 3 3 2 WRKY DNA -binding domain CG-1 PF03859.16 PRP86076.1 - 2.2 8.1 6.3 1.1 9.1 0.5 2.8 3 1 1 4 4 4 0 CG-1 domain APG6_N PF17675.1 PRP86077.1 - 2.4 8.7 107.3 0.032 14.8 15.1 6.6 1 1 5 6 6 6 0 Apg6 coiled-coil region SecE PF00584.20 PRP86078.1 - 2.5e-17 62.6 0.4 2.9e-17 62.3 0.4 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Cu2_monoox_C PF03712.15 PRP86079.1 - 2.2e-20 72.8 0.0 3.2e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PRP86079.1 - 1.3e-12 48.1 0.0 1.9e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain LRR_12 PF18837.1 PRP86079.1 - 0.084 12.5 0.5 0.17 11.6 0.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeat PQ-loop PF04193.14 PRP86080.1 - 2.8e-31 107.1 8.1 1.6e-17 63.0 0.2 3.1 4 0 0 4 4 4 2 PQ loop repeat DUF418 PF04235.12 PRP86080.1 - 0.03 14.3 2.6 0.046 13.6 0.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF418) MFS_1 PF07690.16 PRP86080.1 - 0.5 9.2 7.9 0.2 10.5 5.4 1.7 1 1 0 2 2 2 0 Major Facilitator Superfamily DUF872 PF05915.12 PRP86080.1 - 2.2 8.4 6.6 0.85 9.8 3.1 2.2 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Glyco_transf_64 PF09258.10 PRP86081.1 - 1.1e-49 169.0 0.0 1.7e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain XRCC1_N PF01834.16 PRP86081.1 - 0.026 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 XRCC1 N terminal domain Njmu-R1 PF15053.6 PRP86084.1 - 0.076 12.1 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family GAS PF13851.6 PRP86085.1 - 1.7e-74 249.6 31.7 1.7e-74 249.6 31.7 3.2 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding TFA2_Winged_2 PF18121.1 PRP86085.1 - 0.051 13.3 8.9 0.73 9.6 0.6 3.9 2 1 0 2 2 2 0 TFA2 Winged helix domain 2 BRX_N PF13713.6 PRP86085.1 - 6.8 6.6 8.4 0.21 11.4 1.4 2.2 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Metal_resist PF13801.6 PRP86085.1 - 7.2 6.8 17.8 0.91 9.7 2.1 4.4 5 0 0 5 5 5 0 Heavy-metal resistance Branch PF02485.21 PRP86086.1 - 2.1e-13 50.3 7.7 4.5e-12 46.0 4.9 2.4 2 1 0 2 2 2 2 Core-2/I-Branching enzyme RicinB_lectin_2 PF14200.6 PRP86086.1 - 1e-08 35.7 0.4 8e-06 26.5 0.1 3.4 3 1 1 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Pkinase PF00069.25 PRP86087.1 - 3.6e-55 187.2 0.0 5.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Aldose_epim PF01263.20 PRP86087.1 - 6.4e-54 183.3 0.4 8.7e-54 182.9 0.4 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase_Tyr PF07714.17 PRP86087.1 - 1.1e-26 93.8 0.0 1.5e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PRP86087.1 - 0.00032 20.3 0.0 0.00063 19.4 0.0 1.4 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 PRP86087.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP86087.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PRP86087.1 - 0.03 14.0 0.0 1.1 8.8 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP86087.1 - 0.036 13.4 0.0 0.23 10.8 0.0 2.0 1 1 0 1 1 1 0 Kinase-like DUF2981 PF11200.8 PRP86088.1 - 0.45 10.2 2.8 0.73 9.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) RCC1 PF00415.18 PRP86089.1 - 5.5e-47 158.2 19.4 5.9e-11 42.8 0.1 9.2 9 1 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP86089.1 - 4.2e-34 115.6 21.6 1e-10 41.1 0.6 7.7 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat DnaJ_C PF01556.18 PRP86089.1 - 1.4e-24 86.9 0.0 5.1e-24 85.1 0.0 2.1 1 0 0 1 1 1 1 DnaJ C terminal domain Chromo PF00385.24 PRP86089.1 - 3.6e-21 74.8 4.7 1.9e-10 40.4 0.5 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DnaJ PF00226.31 PRP86089.1 - 2.1e-13 50.2 0.3 6.1e-13 48.7 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain Mtf2_C PF14061.6 PRP86089.1 - 0.00039 20.5 3.5 0.4 10.9 0.1 3.4 3 0 0 3 3 3 2 Polycomb-like MTF2 factor 2 DnaJ_CXXCXGXG PF00684.19 PRP86089.1 - 0.00079 19.7 23.1 0.0016 18.8 13.5 3.4 1 1 1 3 3 3 2 DnaJ central domain Peptidase_Prp PF04327.12 PRP86089.1 - 0.11 12.7 0.0 0.49 10.7 0.0 2.1 1 0 0 1 1 1 0 Cysteine protease Prp APG6_N PF17675.1 PRP86090.1 - 0.0062 17.1 9.9 0.0062 17.1 9.9 3.0 1 1 1 2 2 2 1 Apg6 coiled-coil region Metal_resist PF13801.6 PRP86090.1 - 0.21 11.8 13.2 1.5 9.0 4.6 2.2 2 0 0 2 2 2 0 Heavy-metal resistance MALT1_Ig PF18703.1 PRP86090.1 - 0.28 11.2 9.9 0.1 12.6 6.5 1.9 2 0 0 2 2 2 0 MALT1 Ig-like domain DUF3450 PF11932.8 PRP86090.1 - 3.8 6.7 29.3 0.026 13.8 4.2 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) LMBR1 PF04791.16 PRP86090.1 - 6.2 5.6 19.2 2 7.2 16.8 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Fez1 PF06818.15 PRP86090.1 - 7.4 7.0 35.2 0.12 12.9 18.8 2.1 1 1 1 2 2 2 0 Fez1 eIF-5_eIF-2B PF01873.17 PRP86091.1 - 1.6e-22 79.6 0.4 4e-22 78.3 0.0 1.8 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 PRP86091.1 - 2.2e-13 50.1 6.1 2.2e-13 50.1 6.1 4.2 4 3 1 5 5 3 1 eIF4-gamma/eIF5/eIF2-epsilon RNA_pol_3_Rpc31 PF11705.8 PRP86091.1 - 0.0029 17.9 4.5 0.0029 17.9 4.5 3.1 2 1 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 Dsh_C PF12316.8 PRP86091.1 - 0.54 10.6 8.6 1.3 9.4 8.6 1.6 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Ndc1_Nup PF09531.10 PRP86091.1 - 0.97 8.0 7.4 1.3 7.6 7.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AIM3 PF17096.5 PRP86091.1 - 1.9 9.5 14.7 1 10.3 4.0 2.7 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 G6B PF15096.6 PRP86091.1 - 1.9 8.2 9.1 1 9.1 0.9 2.3 1 1 1 2 2 2 0 G6B family Presenilin PF01080.17 PRP86091.1 - 2.1 7.0 13.3 3.2 6.4 13.3 1.3 1 0 0 1 1 1 0 Presenilin Hydin_ADK PF17213.3 PRP86091.1 - 2.4 8.4 10.2 4.8 7.4 10.2 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain SLC12 PF03522.15 PRP86091.1 - 2.8 6.9 15.3 3.9 6.4 15.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DAP PF15228.6 PRP86091.1 - 7.9 7.7 20.0 9.1 7.5 6.0 2.8 1 1 1 2 2 2 0 Death-associated protein EGF_2 PF07974.13 PRP86094.1 - 0.1 13.0 9.7 0.22 11.9 9.7 1.5 1 0 0 1 1 1 0 EGF-like domain CDO_I PF05995.12 PRP86095.1 - 2e-26 92.3 0.1 2.5e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 PRP86095.1 - 0.00011 21.8 0.5 0.00013 21.5 0.5 1.1 1 0 0 1 1 1 1 PCO_ADO Cupin_2 PF07883.11 PRP86095.1 - 0.015 15.0 0.8 0.12 12.1 0.3 2.1 2 0 0 2 2 2 0 Cupin domain Homeodomain PF00046.29 PRP86097.1 - 8.5e-17 60.8 1.8 8.5e-17 60.8 1.8 1.5 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP86097.1 - 2.8e-05 23.9 0.7 2.8e-05 23.9 0.7 1.8 2 0 0 2 2 2 1 Homeobox KN domain DUF4770 PF15994.5 PRP86097.1 - 0.047 13.9 0.5 0.054 13.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) MutL_C PF08676.11 PRP86098.1 - 6.6e-24 84.4 0.0 2.1e-22 79.5 0.0 2.3 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 PRP86098.1 - 1.6e-23 82.6 0.0 3.2e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PRP86098.1 - 3.9e-11 42.9 0.4 1.2e-10 41.4 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PRP86098.1 - 5e-05 23.8 0.7 0.00014 22.3 0.7 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FtsX PF02687.21 PRP86100.1 - 0.0032 17.9 4.3 0.31 11.5 0.8 2.4 2 0 0 2 2 2 2 FtsX-like permease family Chordopox_A13L PF05961.11 PRP86100.1 - 1.4 9.2 8.8 5.7 7.2 0.2 2.5 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF2672 PF10878.8 PRP86101.1 - 0.1 12.6 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Endomucin PF07010.12 PRP86101.1 - 2.4 8.1 38.9 3.3 7.6 38.9 1.2 1 0 0 1 1 1 0 Endomucin SOG2 PF10428.9 PRP86101.1 - 9.7 5.3 22.3 13 4.8 22.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SAP18 PF06487.12 PRP86103.1 - 1.2e-21 77.4 0.3 1.7e-14 54.2 0.0 2.1 1 1 1 2 2 2 2 Sin3 associated polypeptide p18 (SAP18) DnaJ PF00226.31 PRP86104.1 - 1.7e-06 28.0 0.1 4.7e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 DnaJ domain Pkinase_Tyr PF07714.17 PRP86105.1 - 1.2e-22 80.4 0.0 8.1e-21 74.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86105.1 - 5.8e-13 48.8 0.0 1.5e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP86105.1 - 3.4e-11 43.5 2.9 9e-11 42.1 2.9 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_8 PF13855.6 PRP86105.1 - 1.5e-06 27.9 6.2 6.8e-06 25.8 3.1 2.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PRP86105.1 - 1.5e-05 25.2 11.8 0.0003 21.1 1.7 4.6 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP86105.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 PRP86105.1 - 0.087 12.9 0.2 0.087 12.9 0.2 4.5 6 0 0 6 6 6 0 Leucine Rich repeat Putative_PNPOx PF01243.20 PRP86106.1 - 5.3e-07 29.7 0.1 7.9e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 PRP86106.1 - 0.00039 21.0 0.0 0.19 12.4 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 PRP86106.1 - 0.0093 16.1 0.0 0.018 15.2 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain UBA_3 PF09288.10 PRP86106.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain VPS9 PF02204.18 PRP86107.1 - 1.8e-09 37.7 0.0 6.4e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 PRP86107.1 - 2e-09 37.5 0.1 3.3e-06 27.0 0.0 2.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase RasGEF PF00617.19 PRP86108.1 - 1.3e-40 139.5 0.5 2.7e-40 138.4 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain Lipase_3 PF01764.25 PRP86108.1 - 2.4e-33 115.0 0.0 4.5e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 PRP86108.1 - 0.0015 18.1 0.1 0.0033 17.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) RasGEF_N PF00618.20 PRP86108.1 - 0.011 15.9 0.1 0.078 13.2 0.0 2.3 2 0 0 2 2 2 0 RasGEF N-terminal motif Abhydrolase_6 PF12697.7 PRP86108.1 - 0.03 14.9 0.0 0.059 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Phos_pyr_kin PF08543.12 PRP86109.1 - 1.3e-10 41.1 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 PRP86109.1 - 5.1e-07 29.3 0.0 1.7e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Acetyltransf_1 PF00583.25 PRP86110.1 - 1.7e-10 41.2 0.0 1.7e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP86110.1 - 4.3e-07 30.3 0.0 6.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP86110.1 - 9e-06 25.6 0.1 3.5e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP86110.1 - 0.0029 17.5 0.1 0.3 11.1 0.1 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 PRP86110.1 - 0.022 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Cyclin_N PF00134.23 PRP86111.1 - 3.5e-22 78.5 1.3 5.1e-22 78.0 0.2 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP86111.1 - 1.5e-05 25.0 1.8 4.6e-05 23.5 1.8 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mating_C PF12737.7 PRP86111.1 - 0.33 10.1 6.3 0.45 9.7 6.3 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 RRM_1 PF00076.22 PRP86113.1 - 1.1e-25 89.3 0.0 2e-17 62.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 PRP86113.1 - 0.083 12.8 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 PRP86113.1 - 0.09 12.9 0.0 0.92 9.6 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 RRM_5 PF13893.6 PRP86113.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 PRP86113.1 - 0.22 11.3 0.0 1.6 8.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DAGK_cat PF00781.24 PRP86114.1 - 1.5e-27 95.7 0.0 1.2e-26 92.8 0.0 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain YfdX PF10938.8 PRP86114.1 - 0.052 13.5 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 YfdX protein Cyclin_C PF02984.19 PRP86114.1 - 0.087 12.9 0.2 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Cyclin, C-terminal domain GFO_IDH_MocA PF01408.22 PRP86115.1 - 1.3e-20 74.4 0.0 2.8e-20 73.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PRP86115.1 - 0.00011 22.2 0.0 0.00055 19.9 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.20 PRP86115.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 PRP86115.1 - 0.059 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RhoGEF PF00621.20 PRP86116.1 - 6.5e-23 81.9 0.5 4.9e-22 79.0 0.5 2.0 1 1 0 1 1 1 1 RhoGEF domain C1_1 PF00130.22 PRP86116.1 - 1.1e-08 34.9 0.7 2e-08 34.0 0.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 PRP86116.1 - 0.078 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 C1 domain zf-C3Hc3H PF13891.6 PRP86118.1 - 3.1e-06 27.5 7.1 5.6e-05 23.4 3.2 3.1 1 1 2 3 3 3 3 Potential DNA-binding domain Pkinase_Tyr PF07714.17 PRP86119.1 - 2.7e-30 105.5 0.1 5.1e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86119.1 - 4.2e-19 68.9 0.1 7e-19 68.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP86119.1 - 1.7e-11 44.5 1.9 6.8e-11 42.5 1.9 2.1 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP86119.1 - 0.00017 21.9 18.5 0.03 14.8 4.6 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP86119.1 - 0.099 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Insulin_TMD PF17870.1 PRP86119.1 - 0.81 9.8 2.5 2.6 8.2 2.5 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRR_8 PF13855.6 PRP86119.1 - 5 7.0 13.1 6.7 6.6 0.4 3.0 2 0 0 2 2 2 0 Leucine rich repeat DUF515 PF04415.12 PRP86121.1 - 6.4 5.0 7.1 6.7 5.0 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase_Tyr PF07714.17 PRP86123.1 - 1.1e-67 228.1 0.0 1.6e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86123.1 - 2e-45 155.2 0.0 2.9e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP86123.1 - 3.2e-45 151.7 77.9 9e-08 31.8 0.9 14.1 11 2 3 14 14 14 14 Leucine rich repeat LRR_4 PF12799.7 PRP86123.1 - 3e-28 97.4 86.4 0.00024 21.4 0.2 16.1 13 5 3 18 18 16 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP86123.1 - 4.4e-09 35.7 52.0 3.1 8.1 1.0 16.3 17 0 0 17 17 16 3 Leucine Rich repeat LRR_1 PF00560.33 PRP86123.1 - 1.1e-07 31.3 67.8 6.7 7.7 0.1 21.0 21 3 0 21 21 19 2 Leucine Rich Repeat Amnionless PF14828.6 PRP86123.1 - 3e-05 23.0 0.4 8.1e-05 21.6 0.1 1.7 2 0 0 2 2 2 1 Amnionless Kdo PF06293.14 PRP86123.1 - 0.00023 20.6 0.1 0.00043 19.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP86123.1 - 0.004 16.0 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP86123.1 - 0.0046 16.3 0.1 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Stevor PF17410.2 PRP86123.1 - 0.028 14.0 1.0 0.036 13.6 0.0 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame EphA2_TM PF14575.6 PRP86123.1 - 0.12 13.3 0.4 0.29 12.0 0.4 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 PRP86123.1 - 0.21 11.6 0.8 0.54 10.3 0.8 1.6 1 0 0 1 1 1 0 DAP10 membrane protein SKG6 PF08693.10 PRP86123.1 - 0.56 9.7 7.3 1.2 8.7 7.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4690 PF15756.5 PRP86123.1 - 0.98 10.1 7.7 0.094 13.3 2.3 2.1 3 0 0 3 3 1 0 Small Novel Rich in Cartilage Syndecan PF01034.20 PRP86123.1 - 3.5 7.6 4.8 7.7 6.5 4.8 1.5 1 0 0 1 1 1 0 Syndecan domain Vint PF14623.6 PRP86125.1 - 3.1e-37 128.0 0.0 6.9e-37 126.8 0.0 1.6 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.6 PRP86125.1 - 7.2e-21 74.1 0.0 1.4e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.6 PRP86125.1 - 6.4e-16 58.9 0.1 1.5e-15 57.8 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP86125.1 - 1.9e-14 54.3 0.0 3.7e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PRP86125.1 - 4e-12 46.4 0.0 1.6e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain Hint PF01079.20 PRP86125.1 - 6.7e-05 22.5 0.1 0.00015 21.3 0.1 1.5 1 0 0 1 1 1 1 Hint module VWA_CoxE PF05762.14 PRP86125.1 - 0.0017 17.8 0.1 0.55 9.6 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein RE_HindVP PF09519.10 PRP86125.1 - 0.26 10.3 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease Pkinase_Tyr PF07714.17 PRP86127.1 - 7e-34 117.3 0.5 1.9e-33 115.8 0.5 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86127.1 - 7.4e-27 94.4 0.1 1.3e-26 93.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP86127.1 - 1.8e-07 31.6 7.0 1.8e-07 31.6 7.0 2.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif DUF2857 PF11198.8 PRP86128.1 - 0.029 14.2 0.4 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) Peptidase_C97 PF05903.14 PRP86129.1 - 2.2e-34 118.5 0.0 3.7e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 PRP86129.1 - 2.9e-15 56.3 0.3 4.4e-15 55.7 0.3 1.3 1 1 0 1 1 1 1 PUL domain NHL PF01436.21 PRP86130.1 - 0.0068 16.4 2.8 0.0084 16.1 0.6 2.3 2 0 0 2 2 2 1 NHL repeat LAP1C PF05609.12 PRP86131.1 - 0.17 10.9 23.0 0.26 10.3 23.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) AA_permease_C PF13906.6 PRP86135.1 - 0.051 13.6 2.4 0.11 12.6 2.4 1.5 1 1 0 1 1 1 0 C-terminus of AA_permease Peptidase_S28 PF05577.12 PRP86137.1 - 3.4e-139 464.4 0.5 4.2e-139 464.1 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 PRP86137.1 - 0.0012 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 PRP86137.1 - 0.073 12.2 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Acyltransf_C PF16076.5 PRP86139.1 - 1.8e-17 63.2 0.7 5.1e-17 61.7 0.3 2.0 2 0 0 2 2 2 1 Acyltransferase C-terminus Homeodomain PF00046.29 PRP86139.1 - 2.2e-14 53.0 4.1 2.2e-14 53.0 4.1 2.0 2 0 0 2 2 2 1 Homeodomain Acyltransferase PF01553.21 PRP86139.1 - 4e-14 52.4 0.0 1.4e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Homeobox_KN PF05920.11 PRP86139.1 - 3.3e-05 23.7 1.0 0.0001 22.1 1.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain DUF92 PF01940.16 PRP86139.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF92 PLC-beta_C PF08703.10 PRP86139.1 - 0.33 10.9 3.5 0.18 11.8 0.8 1.8 2 0 0 2 2 2 0 PLC-beta C terminal DSPc PF00782.20 PRP86140.1 - 1.1e-29 102.9 0.0 1.4e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP86140.1 - 0.0065 16.1 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 PRP86140.1 - 0.18 12.1 0.0 0.64 10.3 0.0 1.8 2 0 0 2 2 2 0 Rit1 DUSP-like domain Pkinase_Tyr PF07714.17 PRP86141.1 - 3.3e-10 39.7 0.2 0.00048 19.5 0.0 3.1 2 1 0 3 3 3 3 Protein tyrosine kinase GPS PF01825.21 PRP86141.1 - 9.5e-10 38.9 3.8 2.2e-09 37.7 3.8 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP86141.1 - 0.00092 18.7 0.1 0.023 14.1 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain DUF4514 PF14986.6 PRP86141.1 - 0.0053 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4514) Syndecan PF01034.20 PRP86141.1 - 0.094 12.6 1.9 0.1 12.5 0.2 1.9 2 0 0 2 2 2 0 Syndecan domain Pkinase PF00069.25 PRP86142.1 - 1.7e-47 162.0 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Hist_deacetyl PF00850.19 PRP86142.1 - 6e-47 160.6 0.0 8.2e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase_Tyr PF07714.17 PRP86142.1 - 2e-23 83.0 0.0 2.6e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP86142.1 - 3.5e-05 23.3 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP86142.1 - 0.00059 18.7 0.0 0.00098 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PRP86142.1 - 0.0017 18.3 0.6 0.0099 15.8 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP86142.1 - 0.0091 15.6 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase FTA2 PF13095.6 PRP86142.1 - 0.028 14.0 0.1 0.06 13.0 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP86142.1 - 0.045 13.1 0.0 2.1 7.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CD36 PF01130.21 PRP86143.1 - 6.8e-33 113.9 0.0 6.5e-21 74.4 0.0 3.4 2 1 0 2 2 2 2 CD36 family DUF3098 PF11297.8 PRP86143.1 - 0.069 12.8 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) EGF_2 PF07974.13 PRP86144.1 - 6.3 7.3 10.1 1.9 8.9 5.7 2.3 2 0 0 2 2 2 0 EGF-like domain HECT PF00632.25 PRP86145.1 - 1.3e-96 323.7 1.6 1.9e-96 323.2 1.6 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 PRP86145.1 - 1.9e-13 50.4 1.5 5.2e-13 49.0 1.5 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF3405 PF11885.8 PRP86147.1 - 2.2e-12 46.4 0.5 7.5e-12 44.6 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) DUF3670 PF12419.8 PRP86147.1 - 0.0079 16.0 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 Helicase protein DEAD PF00270.29 PRP86148.1 - 8.5e-48 162.4 0.0 1.6e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP86148.1 - 2.8e-27 95.3 0.0 2e-25 89.3 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP86148.1 - 1.5e-07 31.6 1.7 2.9e-07 30.6 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PRP86148.1 - 1.4e-05 24.9 0.3 0.0063 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain ERCC3_RAD25_C PF16203.5 PRP86148.1 - 5e-05 22.6 0.0 5e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 PRP86148.1 - 0.0037 17.6 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Apt1 PF10351.9 PRP86148.1 - 0.038 12.8 9.3 0.06 12.2 9.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 PRP86148.1 - 0.32 10.6 29.6 0.66 9.5 29.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 PRP86148.1 - 0.65 8.2 15.4 1 7.6 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 PRP86148.1 - 0.83 8.5 9.8 1.5 7.6 9.8 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 PRP86148.1 - 1.3 8.1 5.2 2.1 7.5 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SOBP PF15279.6 PRP86148.1 - 4.1 7.9 8.8 8 7.0 8.8 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein CCDC106 PF15794.5 PRP86148.1 - 6.5 6.4 17.9 13 5.5 17.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SLC12 PF03522.15 PRP86148.1 - 6.6 5.6 11.3 16 4.4 11.3 1.5 1 0 0 1 1 1 0 Solute carrier family 12 RP-C_C PF11800.8 PRP86148.1 - 7.4 6.6 6.8 16 5.5 6.8 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region PGA2 PF07543.12 PRP86148.1 - 9.6 6.2 17.9 6.4 6.7 13.5 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_S9 PF00380.19 PRP86149.1 - 3.1e-29 102.0 1.7 3.3e-29 101.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S9/S16 ADIP PF11559.8 PRP86149.1 - 0.0038 17.3 4.5 0.0038 17.3 4.5 4.8 2 1 3 5 5 5 2 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 PRP86149.1 - 0.018 15.7 5.5 0.018 15.7 5.5 4.7 3 1 1 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-F_leu_zip PF10473.9 PRP86149.1 - 0.048 13.7 38.7 0.31 11.1 7.0 4.0 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 PRP86149.1 - 0.091 13.0 12.3 0.19 12.0 0.1 4.5 5 0 0 5 5 5 0 Homeobox associated leucine zipper DMPK_coil PF08826.10 PRP86149.1 - 0.11 12.6 0.3 0.11 12.6 0.3 4.5 3 2 2 5 5 5 0 DMPK coiled coil domain like Cep57_CLD_2 PF14197.6 PRP86149.1 - 0.45 10.6 23.2 0.84 9.8 6.2 5.4 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 TSC22 PF01166.18 PRP86149.1 - 0.52 10.7 9.5 4 7.8 0.1 5.2 3 1 0 4 4 4 0 TSC-22/dip/bun family DUF4349 PF14257.6 PRP86149.1 - 1.9 7.9 15.0 0.46 9.9 6.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) p450 PF00067.22 PRP86150.1 - 7e-52 176.7 0.0 8.4e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4787 PF16029.5 PRP86151.1 - 1.7e-07 31.2 0.7 4.1e-07 30.0 0.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4787) KH_6 PF15985.5 PRP86152.1 - 5.9e-13 49.0 0.3 1.4e-12 47.8 0.1 1.8 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 PRP86152.1 - 0.00036 20.4 0.1 0.0028 17.5 0.0 2.3 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain p31comet PF06581.12 PRP86152.1 - 0.17 11.0 0.8 0.25 10.5 0.8 1.2 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Pkinase PF00069.25 PRP86153.1 - 7.9e-62 209.0 0.1 1.9e-61 207.7 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86153.1 - 1.6e-30 106.2 0.0 2.8e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.7 PRP86153.1 - 3.1e-05 24.2 0.0 2.6 8.3 0.0 3.7 3 0 0 3 3 3 2 PAS domain Pkinase_fungal PF17667.1 PRP86153.1 - 5.2e-05 22.2 0.0 0.00011 21.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP86153.1 - 5.3e-05 22.7 0.0 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 PRP86153.1 - 0.00056 19.6 0.2 0.0013 18.4 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 PRP86153.1 - 0.00065 19.4 0.5 0.0032 17.1 0.5 2.2 1 1 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PRP86153.1 - 0.0015 17.5 0.2 0.0039 16.2 0.2 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP86153.1 - 0.0078 15.6 0.4 0.032 13.6 0.5 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Med26 PF08711.11 PRP86154.1 - 4.9e-12 45.7 0.1 1.6e-11 44.0 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_S20p PF01649.18 PRP86154.1 - 0.44 11.2 2.9 1.9 9.2 2.9 2.1 1 0 0 1 1 1 0 Ribosomal protein S20 HSP20 PF00011.21 PRP86155.1 - 8.8e-20 70.8 1.2 1.1e-19 70.4 1.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP86155.1 - 8.1e-07 28.5 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 PRP86155.1 - 0.024 14.0 0.5 0.049 13.0 0.5 1.5 1 1 0 1 1 1 0 Putative adhesin BON PF04972.17 PRP86155.1 - 0.075 13.4 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 BON domain Esterase_phd PF10503.9 PRP86157.1 - 0.00028 20.4 0.1 0.0013 18.3 0.1 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 PRP86157.1 - 0.0013 18.3 0.1 0.017 14.6 0.1 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family PAN_1 PF00024.26 PRP86157.1 - 0.0056 16.6 0.9 0.011 15.7 0.9 1.5 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 PRP86157.1 - 0.007 16.2 0.6 0.017 14.9 0.6 1.6 1 0 0 1 1 1 1 PAN-like domain Esterase PF00756.20 PRP86157.1 - 0.0093 15.6 0.1 0.016 14.9 0.1 1.5 1 1 0 1 1 1 1 Putative esterase PAN_4 PF14295.6 PRP86157.1 - 0.046 13.6 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 PAN domain Abhydrolase_6 PF12697.7 PRP86157.1 - 0.066 13.8 0.1 0.1 13.2 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 PRP86157.1 - 0.079 11.6 0.0 2.3 6.8 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) CLASP_N PF12348.8 PRP86158.1 - 4.6e-21 75.4 0.4 6.3e-21 75.0 0.4 1.1 1 0 0 1 1 1 1 CLASP N terminal TIP120 PF08623.10 PRP86158.1 - 0.00085 19.1 1.2 0.3 10.9 0.0 2.2 2 0 0 2 2 2 2 TATA-binding protein interacting (TIP20) HEAT PF02985.22 PRP86158.1 - 0.0015 18.6 0.2 0.21 11.9 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 PRP86158.1 - 0.081 13.0 0.2 1 9.4 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 PRP86158.1 - 0.2 11.8 0.4 3.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 EcoEI_R_C PF08463.10 PRP86158.1 - 0.38 10.8 2.7 1.8 8.7 1.0 2.3 2 1 1 3 3 3 0 EcoEI R protein C-terminal Pkinase PF00069.25 PRP86160.1 - 2.6e-70 236.8 0.0 3.6e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86160.1 - 1.6e-35 122.6 0.0 2.4e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.7 PRP86160.1 - 1.7e-13 50.7 0.0 8.4e-05 22.8 0.0 4.4 4 0 0 4 4 4 2 PAS domain RIO1 PF01163.22 PRP86160.1 - 4.4e-07 29.7 0.3 7e-07 29.0 0.3 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PRP86160.1 - 5.9e-06 25.8 0.0 2e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP86160.1 - 6.3e-06 25.7 0.1 9.9e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.10 PRP86160.1 - 3.3e-05 24.1 0.0 1.1 9.5 0.0 3.9 4 0 0 4 4 4 2 PAS fold PAS_3 PF08447.12 PRP86160.1 - 0.00011 22.4 0.0 35 4.8 0.0 4.9 5 0 0 5 5 5 0 PAS fold PAS PF00989.25 PRP86160.1 - 0.0033 17.4 0.0 0.24 11.4 0.0 3.5 4 0 0 4 4 4 1 PAS fold APH PF01636.23 PRP86160.1 - 0.0052 16.7 0.1 0.0087 16.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP86160.1 - 0.0071 15.2 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP86160.1 - 0.0095 14.9 0.1 0.014 14.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PAS_8 PF13188.7 PRP86160.1 - 0.036 14.1 0.0 8 6.6 0.0 2.8 3 0 0 3 3 3 0 PAS domain Choline_kinase PF01633.20 PRP86160.1 - 0.064 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Atg8 PF02991.16 PRP86161.1 - 2.7e-44 149.6 0.5 4.1e-44 149.0 0.1 1.5 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 PRP86161.1 - 1.8e-06 28.2 0.2 9.4e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 DUF2254 PF10011.9 PRP86162.1 - 4.1e-12 45.6 6.4 7.1e-12 44.8 6.4 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) KAP_NTPase PF07693.14 PRP86162.1 - 0.13 11.5 0.5 0.78 8.9 0.1 2.1 2 0 0 2 2 2 0 KAP family P-loop domain Neurensin PF14927.6 PRP86162.1 - 0.35 10.6 6.4 0.3 10.8 0.2 2.5 1 1 0 2 2 2 0 Neurensin Peptidase_S49 PF01343.18 PRP86164.1 - 0.00028 20.9 0.0 0.00052 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 CUE PF02845.16 PRP86165.1 - 0.00031 20.4 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain Herpes_Helicase PF02689.14 PRP86166.1 - 0.068 11.1 0.0 0.074 11.0 0.0 1.0 1 0 0 1 1 1 0 Helicase Ras PF00071.22 PRP86167.1 - 4.4e-62 208.5 0.0 5.1e-62 208.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP86167.1 - 8.4e-33 113.1 0.0 1.2e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP86167.1 - 1.7e-13 50.4 0.0 2.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP86167.1 - 2.4e-05 24.4 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP86167.1 - 0.00056 19.9 0.2 0.073 13.0 0.0 2.2 1 1 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 PRP86167.1 - 0.0073 16.0 0.1 0.011 15.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PRP86167.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain MraZ PF02381.18 PRP86167.1 - 0.013 15.5 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like Gtr1_RagA PF04670.12 PRP86167.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ATPase_2 PF01637.18 PRP86167.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SRPRB PF09439.10 PRP86167.1 - 0.049 13.1 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PRP86167.1 - 0.054 13.0 0.0 0.18 11.3 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 PRP86167.1 - 0.07 13.6 0.1 0.093 13.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 PRP86167.1 - 0.091 12.8 0.1 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP86167.1 - 0.095 12.5 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP86167.1 - 0.1 13.0 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 PRP86167.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 LRR_9 PF14580.6 PRP86168.1 - 4.9e-21 75.0 2.8 6.8e-21 74.5 2.8 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PRP86168.1 - 1.9e-12 47.2 14.5 1.1e-08 35.2 3.2 4.1 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP86168.1 - 5.1e-09 35.8 6.6 2.5e-07 30.4 4.0 3.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 PRP86168.1 - 0.051 13.7 1.4 10 6.5 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat PBSX_XtrA PF17356.2 PRP86168.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage-like element PBSX protein XtrA LRR_1 PF00560.33 PRP86168.1 - 2.3 9.1 5.9 29 5.7 0.1 4.3 4 1 1 5 5 5 0 Leucine Rich Repeat AAA_16 PF13191.6 PRP86169.1 - 3.8e-37 128.3 0.0 1.3e-36 126.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Response_reg PF00072.24 PRP86169.1 - 3.6e-24 85.1 0.2 1e-23 83.6 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.25 PRP86169.1 - 1.4e-23 83.6 1.8 3.5e-22 79.0 0.0 3.6 4 0 0 4 4 4 1 Protein kinase domain HATPase_c PF02518.26 PRP86169.1 - 8.1e-18 65.0 0.2 3e-17 63.1 0.2 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_Tyr PF07714.17 PRP86169.1 - 1.7e-16 60.3 0.0 1.7e-16 60.3 0.0 2.5 4 0 0 4 4 4 1 Protein tyrosine kinase HisKA PF00512.25 PRP86169.1 - 5.2e-10 39.2 1.6 1.1e-09 38.1 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 PRP86169.1 - 1.4e-08 35.1 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PRP86169.1 - 3.5e-08 34.2 0.1 7.7e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 PRP86169.1 - 0.00055 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA PF00004.29 PRP86169.1 - 0.01 16.3 2.5 0.39 11.1 0.0 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DDE_Tnp_ISL3 PF01610.17 PRP86169.1 - 0.016 14.9 0.1 1.1 8.9 0.0 2.7 2 0 0 2 2 2 0 Transposase GAF_3 PF13492.6 PRP86169.1 - 0.022 15.1 0.1 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 GAF domain RsgA_GTPase PF03193.16 PRP86169.1 - 0.043 13.7 0.1 0.16 11.9 0.1 1.9 1 0 0 1 1 1 0 RsgA GTPase Kdo PF06293.14 PRP86169.1 - 0.052 12.9 0.1 0.17 11.2 0.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4599 PF15371.6 PRP86169.1 - 0.18 12.3 0.9 1 9.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Grg1 PF11034.8 PRP86170.1 - 3.7e-31 107.2 10.3 4.7e-31 106.8 10.3 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 DUF4100 PF13352.6 PRP86170.1 - 0.0051 16.6 2.4 0.0063 16.3 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4100) PRA1 PF03208.19 PRP86171.1 - 2.1e-30 105.2 4.0 2.8e-30 104.8 4.0 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2537 PF10801.8 PRP86171.1 - 0.056 13.7 0.8 0.056 13.7 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) zf_CCCH_4 PF18345.1 PRP86172.1 - 1e-09 38.1 5.8 6.7e-05 22.8 0.4 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 PRP86172.1 - 1e-07 31.6 3.8 0.00042 20.1 0.4 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 PRP86172.1 - 1.5e-06 28.0 4.4 0.016 15.1 0.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PRP86172.1 - 0.13 12.8 4.2 5.4 7.6 0.2 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PRP86172.1 - 0.16 12.7 0.2 0.16 12.7 0.2 3.5 2 1 1 4 4 4 0 Torus domain Roc PF08477.13 PRP86173.1 - 9.5e-12 45.2 0.4 1.5e-11 44.6 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PRP86173.1 - 7e-10 38.7 0.0 8.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PRP86173.1 - 2.2e-06 27.8 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP86173.1 - 7.3e-05 22.4 0.0 9.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 PRP86173.1 - 0.0002 20.8 0.1 0.00063 19.2 0.1 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP86173.1 - 0.00074 18.9 0.0 0.0017 17.8 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 PRP86173.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.5 1 1 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 PRP86173.1 - 0.021 15.3 0.4 0.029 14.9 0.4 1.4 1 1 0 1 1 1 0 ABC transporter PA PF02225.22 PRP86173.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 PA domain CBF PF03914.17 PRP86174.1 - 7e-40 136.8 2.4 3.8e-39 134.4 0.0 2.9 3 0 0 3 3 3 1 CBF/Mak21 family DUF5578 PF17741.1 PRP86174.1 - 0.00063 19.2 0.9 0.14 11.5 0.1 3.0 3 0 0 3 3 3 1 Family of unknown function (DUF5578) Cnd1 PF12717.7 PRP86174.1 - 0.023 14.7 5.0 0.15 12.1 0.3 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 PRP86174.1 - 0.03 14.3 1.0 11 5.9 0.1 2.9 2 1 1 3 3 3 0 Sister chromatid cohesion C-terminus Adaptin_N PF01602.20 PRP86174.1 - 0.041 12.4 4.4 1.8 7.0 4.4 2.1 1 1 0 1 1 1 0 Adaptin N terminal region CPP1-like PF11833.8 PRP86174.1 - 0.077 12.6 1.2 0.16 11.6 1.2 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Spore_GerQ PF09671.10 PRP86174.1 - 0.12 12.4 0.3 0.47 10.5 0.1 2.1 2 0 0 2 2 2 0 Spore coat protein (Spore_GerQ) RICTOR_M PF14666.6 PRP86174.1 - 0.14 11.9 1.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain IBR PF01485.21 PRP86175.1 - 6.4e-10 39.1 5.8 6.4e-10 39.1 5.8 10.1 5 3 3 8 8 8 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 PRP86175.1 - 4e-08 33.4 6.6 4e-08 33.4 6.6 8.5 6 2 2 8 8 8 2 Ring finger domain zf-RING_5 PF14634.6 PRP86175.1 - 1.7e-05 24.7 21.7 0.00061 19.7 5.3 9.0 7 3 2 9 9 9 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 PRP86175.1 - 3.6e-05 23.7 13.5 0.0007 19.6 2.1 6.4 8 0 0 8 8 8 2 RING-type zinc-finger C1_4 PF07975.12 PRP86175.1 - 0.027 14.7 4.3 0.027 14.7 4.3 8.8 8 2 2 10 10 10 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 PRP86175.1 - 0.047 13.6 0.1 0.047 13.6 0.1 5.7 7 0 0 7 7 7 0 zinc-finger of a C2HC-type Sas10_Utp3 PF04000.15 PRP86176.1 - 3e-20 72.6 0.1 1.7e-19 70.2 0.1 2.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Sas10 PF09368.10 PRP86176.1 - 1.7e-14 54.0 7.7 1.7e-14 54.0 7.7 2.7 3 0 0 3 3 3 1 Sas10 C-terminal domain Ribophorin_I PF04597.14 PRP86177.1 - 1.3e-120 403.6 9.6 1.5e-120 403.4 9.6 1.0 1 0 0 1 1 1 1 Ribophorin I SpaA PF17802.1 PRP86177.1 - 0.046 14.1 1.7 0.41 11.0 1.3 2.6 2 0 0 2 2 2 0 Prealbumin-like fold domain HisKA_4TM PF16926.5 PRP86178.1 - 0.084 12.4 0.5 0.21 11.2 0.5 1.5 1 1 0 1 1 1 0 Archaeal 4TM region of histidine kinase PPR_3 PF13812.6 PRP86179.1 - 2e-21 75.8 5.0 1.1e-06 28.6 0.4 3.6 2 1 0 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 PRP86179.1 - 6.4e-18 64.7 4.4 9.3e-05 22.5 0.1 5.7 1 1 3 5 5 5 5 PPR repeat family PPR_long PF17177.4 PRP86179.1 - 2.5e-10 40.1 0.7 0.00014 21.3 0.1 3.4 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PRP86179.1 - 4.4e-06 26.6 10.7 0.97 9.8 0.0 6.0 6 1 0 6 6 6 3 PPR repeat Ufm1 PF03671.14 PRP86179.1 - 0.00095 19.2 0.0 0.0047 17.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin fold modifier 1 protein Troponin PF00992.20 PRP86179.1 - 0.0046 17.3 1.5 0.0046 17.3 1.5 2.4 2 1 0 2 2 2 1 Troponin PX PF00787.24 PRP86179.1 - 0.011 15.7 0.4 0.036 14.1 0.4 1.8 1 0 0 1 1 1 0 PX domain DUF3368 PF11848.8 PRP86179.1 - 0.014 15.2 0.1 0.18 11.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) PPR_1 PF12854.7 PRP86179.1 - 0.028 14.1 1.0 5.4 6.8 0.0 3.8 3 1 0 3 3 3 0 PPR repeat SPOB_a PF14689.6 PRP86179.1 - 0.043 13.5 1.3 0.87 9.3 0.0 3.5 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain Tyrosinase PF00264.20 PRP86179.1 - 0.075 13.3 0.8 0.17 12.1 0.8 1.6 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF2420 PF10336.9 PRP86179.1 - 0.13 12.2 1.4 7.8 6.6 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2420) Drf_DAD PF06345.11 PRP86179.1 - 1.8 8.8 3.5 1.8 8.8 0.6 2.2 2 0 0 2 2 2 0 DRF Autoregulatory Domain Ank_2 PF12796.7 PRP86180.1 - 1.9e-40 137.3 5.0 1.9e-10 41.2 0.0 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP86180.1 - 1.8e-13 50.7 2.8 0.00023 21.7 0.0 4.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP86180.1 - 1.2e-12 47.7 2.7 0.0029 18.0 0.1 6.3 3 1 3 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 PRP86180.1 - 6.3e-08 32.7 1.2 1.5 9.2 0.0 5.7 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP86180.1 - 1.1e-07 31.6 1.9 5.9 7.8 0.0 7.1 8 0 0 8 8 8 2 Ankyrin repeat Uricase PF01014.18 PRP86181.1 - 2.3e-60 202.6 0.1 1.2e-31 109.6 0.0 2.2 2 0 0 2 2 2 2 Uricase SRP_SPB PF02978.19 PRP86182.1 - 2.2e-14 53.8 0.1 6.2e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Signal peptide binding domain CBP_BcsO PF17037.5 PRP86182.1 - 0.022 14.9 5.1 0.044 13.9 5.1 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO UPF0183 PF03676.14 PRP86183.1 - 8.5e-116 387.5 1.4 1.2e-115 386.9 1.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) KASH_CCD PF14662.6 PRP86184.1 - 0.0012 18.7 7.5 0.0016 18.3 7.5 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Csm1_N PF18504.1 PRP86184.1 - 0.0013 19.0 5.2 0.068 13.5 0.2 2.6 2 0 0 2 2 2 1 Csm1 N-terminal domain DivIC PF04977.15 PRP86184.1 - 0.0017 18.1 7.5 0.058 13.2 0.3 2.3 2 0 0 2 2 2 2 Septum formation initiator TSC22 PF01166.18 PRP86184.1 - 0.012 15.9 7.7 0.53 10.6 1.4 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family Anti-adapt_IraP PF10796.9 PRP86184.1 - 0.013 16.1 4.7 1 10.0 0.5 2.6 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein DUF3450 PF11932.8 PRP86184.1 - 0.024 13.9 7.3 0.033 13.5 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 PRP86184.1 - 0.027 14.7 11.1 0.036 14.3 11.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Swi5 PF07061.11 PRP86184.1 - 0.03 14.4 4.5 0.21 11.7 0.8 2.4 2 0 0 2 2 2 0 Swi5 ABC_tran_CTD PF16326.5 PRP86184.1 - 0.044 14.0 12.8 0.36 11.1 3.4 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain UPF0242 PF06785.11 PRP86184.1 - 0.054 13.6 10.6 0.19 11.8 9.5 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Mto2_bdg PF12808.7 PRP86184.1 - 0.085 13.2 15.1 0.66 10.3 4.5 2.5 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DNA_gyraseB PF00204.25 PRP86184.1 - 0.15 11.5 1.0 7 6.1 0.0 2.1 1 1 1 2 2 2 0 DNA gyrase B SlyX PF04102.12 PRP86184.1 - 0.18 12.5 8.3 1.6 9.4 1.2 2.5 2 0 0 2 2 2 0 SlyX Macoilin PF09726.9 PRP86184.1 - 0.24 9.9 5.6 0.24 9.9 5.6 1.0 1 0 0 1 1 1 0 Macoilin family DUF2316 PF10078.9 PRP86184.1 - 0.24 11.7 3.6 7.9 6.8 2.4 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) TMPIT PF07851.13 PRP86184.1 - 0.26 10.5 4.4 0.33 10.1 4.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein BBP1_C PF15272.6 PRP86184.1 - 0.39 10.5 8.5 0.072 12.9 1.9 2.0 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal FlaC_arch PF05377.11 PRP86184.1 - 0.42 11.0 5.5 2.2 8.7 0.5 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIVA PF05103.13 PRP86184.1 - 0.49 10.5 6.4 2 8.5 0.7 2.3 1 1 1 2 2 2 0 DivIVA protein bZIP_2 PF07716.15 PRP86184.1 - 0.52 10.4 11.4 1.4 9.1 2.2 2.6 2 0 0 2 2 2 0 Basic region leucine zipper DUF4200 PF13863.6 PRP86184.1 - 0.71 10.3 10.4 2 8.8 10.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) KIAA1430 PF13879.6 PRP86184.1 - 0.72 10.6 10.6 0.62 10.9 1.5 2.3 1 1 2 3 3 3 0 KIAA1430 homologue YabA PF06156.13 PRP86184.1 - 0.89 10.2 9.1 3.3 8.4 1.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 PRP86184.1 - 1.9 9.0 5.7 4.5 7.8 1.2 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF99 PF01949.16 PRP86184.1 - 2 7.8 4.4 2.4 7.5 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF99 YwqJ-deaminase PF14431.6 PRP86184.1 - 2.3 8.4 6.1 6.9 6.9 2.6 2.1 1 1 1 2 2 2 0 YwqJ-like deaminase FUSC PF04632.12 PRP86184.1 - 2.5 6.5 5.8 3 6.3 5.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family ZapB PF06005.12 PRP86184.1 - 2.6 8.5 14.7 1e+03 0.3 14.6 2.5 1 1 0 1 1 1 0 Cell division protein ZapB NYD-SP28_assoc PF14775.6 PRP86184.1 - 3.3 7.9 8.3 15 5.8 0.6 3.1 2 1 0 2 2 2 0 Sperm tail C-terminal domain CENP-H PF05837.12 PRP86184.1 - 6.3 7.2 11.3 14 6.1 11.2 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 PRP86184.1 - 7.1 7.2 14.2 20 5.7 4.7 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PKcGMP_CC PF16808.5 PRP86184.1 - 9.6 6.2 17.8 0.86 9.5 2.0 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ERCC4 PF02732.15 PRP86185.1 - 1.5e-19 70.7 0.0 4.6e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain GST_N PF02798.20 PRP86186.1 - 5e-16 58.8 0.0 9.4e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP86186.1 - 6.5e-14 51.9 0.1 9.9e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PRP86186.1 - 3.1e-11 43.4 0.0 5.6e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP86186.1 - 7.8e-11 42.2 0.0 1.4e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP86186.1 - 2e-09 37.4 0.0 4.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP86186.1 - 1.9e-07 31.2 0.0 4.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PRP86186.1 - 0.0032 18.0 0.0 0.0057 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AAA_assoc PF14363.6 PRP86186.1 - 0.059 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Tom37 PF10568.9 PRP86186.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 PRP86186.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Met_synt_B12 PF02965.17 PRP86188.1 - 7.9e-116 386.3 0.1 1.6e-115 385.2 0.1 1.6 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 PRP86188.1 - 3.9e-76 256.4 0.0 2.4e-75 253.8 0.0 2.3 2 0 0 2 2 2 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 PRP86188.1 - 2.2e-58 197.8 0.7 9.9e-58 195.7 0.2 2.1 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 PRP86188.1 - 3.3e-25 88.3 0.1 1.2e-24 86.5 0.1 2.1 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 PRP86188.1 - 2.5e-18 66.2 0.5 9e-18 64.5 0.5 2.0 1 0 0 1 1 1 1 B12 binding domain Prefoldin PF02996.17 PRP86189.1 - 1.6e-30 105.5 1.1 1.6e-30 105.5 1.1 1.7 1 1 1 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.11 PRP86189.1 - 0.012 16.1 4.7 3.8 8.1 4.7 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Prefoldin_2 PF01920.20 PRP86189.1 - 0.036 14.0 7.3 0.85 9.6 6.1 2.5 1 1 1 2 2 2 0 Prefoldin subunit CC2-LZ PF16516.5 PRP86189.1 - 0.046 14.1 9.2 0.11 12.9 1.2 2.8 2 2 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CALCOCO1 PF07888.11 PRP86189.1 - 0.17 10.7 5.8 0.16 10.8 1.0 2.0 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like NFACT-R_1 PF05670.13 PRP86190.1 - 3.6e-32 111.3 1.3 7.3e-32 110.3 0.1 2.3 2 0 0 2 2 2 1 NFACT protein RNA binding domain FbpA PF05833.11 PRP86190.1 - 1.4e-31 109.8 34.3 1.4e-31 109.8 34.3 3.1 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 PRP86190.1 - 9.8e-28 96.2 0.0 9.8e-28 96.2 0.0 4.9 6 1 0 6 6 6 1 NFACT protein C-terminal domain PROL5-SMR PF15621.6 PRP86191.1 - 0.0037 17.7 0.0 0.0066 16.9 0.0 1.4 1 0 0 1 1 1 1 Proline-rich submaxillary gland androgen-regulated family ADK PF00406.22 PRP86192.1 - 6.4e-09 36.1 0.1 9.4e-07 29.0 0.0 2.6 2 0 0 2 2 2 1 Adenylate kinase Hydin_ADK PF17213.3 PRP86192.1 - 9.5e-05 22.8 0.1 9.5e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 PRP86192.1 - 0.00032 21.1 0.1 0.00032 21.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain Titin_Ig-rpts PF06582.12 PRP86192.1 - 0.035 14.1 0.9 2.1 8.3 0.1 2.7 2 0 0 2 2 2 0 Titin repeat SKI PF01202.22 PRP86192.1 - 0.043 13.9 0.0 0.043 13.9 0.0 2.3 2 1 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 PRP86192.1 - 0.095 12.9 0.0 0.095 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PRP86192.1 - 0.11 13.0 1.7 1.5 9.3 0.0 3.0 3 0 0 3 3 3 0 ABC transporter Rubis-subs-bind PF09273.11 PRP86193.1 - 3.2e-16 60.2 0.7 9.3e-16 58.7 0.7 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 PRP86193.1 - 1.9e-14 54.4 0.0 3.6e-14 53.5 0.0 1.4 2 0 0 2 2 2 1 SET domain RasGAP PF00616.19 PRP86194.1 - 4.6e-54 183.3 1.6 4.6e-54 183.3 1.6 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 PRP86194.1 - 5.2e-17 62.0 0.1 2.7e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain RasGAP_C PF03836.15 PRP86194.1 - 5.5e-09 36.3 10.3 5.5e-09 36.3 10.3 2.7 4 0 0 4 4 4 1 RasGAP C-terminus HNH_2 PF13391.6 PRP86194.1 - 9.9e-07 28.8 0.0 2.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease CBM_4_9 PF02018.17 PRP86194.1 - 0.099 12.9 14.0 0.055 13.7 4.9 3.3 3 1 0 3 3 3 0 Carbohydrate binding domain Carb_bind PF10645.9 PRP86194.1 - 3.6 7.9 30.2 0.016 15.4 4.0 3.8 3 0 0 3 3 3 0 Carbohydrate binding SWIM PF04434.17 PRP86195.1 - 0.0093 15.6 1.2 0.021 14.5 1.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger PBP1_TM PF14812.6 PRP86195.1 - 4.7 7.7 14.3 0.24 11.8 7.9 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PhzC-PhzF PF02567.16 PRP86196.1 - 6.8e-61 206.2 0.0 8e-61 206.0 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein N_NLPC_P60 PF12912.7 PRP86196.1 - 0.2 12.0 0.1 7.8 6.9 0.0 2.4 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term 5-FTHF_cyc-lig PF01812.20 PRP86197.1 - 2.7e-41 141.5 0.0 6.9e-41 140.2 0.0 1.7 2 0 0 2 2 2 1 5-formyltetrahydrofolate cyclo-ligase family DnaJ PF00226.31 PRP86198.1 - 1.9e-28 98.4 1.8 4.6e-28 97.1 1.8 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 PRP86198.1 - 8.8e-15 54.6 0.0 5e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 PRP86198.1 - 4.7e-09 36.4 0.0 5.1e-06 26.5 0.1 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 PRP86198.1 - 5.3e-06 26.0 0.3 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PRP86198.1 - 0.00013 22.3 0.1 0.64 10.5 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PRP86198.1 - 0.0015 18.8 0.7 1 9.8 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like adh_short PF00106.25 PRP86199.1 - 5.4e-37 127.1 0.3 6.7e-28 97.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP86199.1 - 1e-29 103.8 0.0 6.9e-20 71.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP86199.1 - 1.3e-08 34.9 0.1 1.9e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP86199.1 - 6.3e-07 29.1 0.3 9e-06 25.3 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PRP86199.1 - 0.011 14.8 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fe_hyd_lg_C PF02906.14 PRP86199.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain GDP_Man_Dehyd PF16363.5 PRP86199.1 - 0.07 12.5 0.7 0.087 12.2 0.1 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PMSR PF01625.21 PRP86200.1 - 1.5e-57 194.1 0.2 1.9e-57 193.8 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Aldo_ket_red PF00248.21 PRP86201.1 - 2.1e-63 214.3 0.0 2.4e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PDEase_I PF00233.19 PRP86202.1 - 3.6e-83 278.9 3.1 3.6e-83 278.9 3.1 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 PRP86202.1 - 6.9e-10 39.1 0.0 2.3e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain Porin_8 PF16966.5 PRP86202.1 - 0.038 12.9 0.1 0.064 12.2 0.1 1.2 1 0 0 1 1 1 0 Porin-like glycoporin RafY Fez1 PF06818.15 PRP86202.1 - 0.59 10.6 36.8 0.43 11.0 15.4 3.4 3 0 0 3 3 3 0 Fez1 DUF866 PF05907.13 PRP86203.1 - 2.4e-40 138.0 0.0 2.7e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn-ribbon_8 PF09723.10 PRP86203.1 - 0.0097 16.0 1.8 0.036 14.2 1.8 2.0 1 1 0 1 1 1 1 Zinc ribbon domain DUF4720 PF15846.5 PRP86203.1 - 0.021 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) OrfB_Zn_ribbon PF07282.11 PRP86203.1 - 0.086 12.8 0.6 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_4 PF13717.6 PRP86203.1 - 0.17 11.9 3.3 1.3 9.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain C1_2 PF03107.16 PRP86203.1 - 0.66 10.3 5.1 2.3 8.6 0.5 2.4 1 1 1 2 2 2 0 C1 domain G-alpha PF00503.20 PRP86204.1 - 8.3e-91 304.8 20.7 8.8e-89 298.1 20.7 2.9 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PRP86204.1 - 4.4e-06 26.3 1.1 0.083 12.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family MFS_1 PF07690.16 PRP86205.1 - 1.2e-38 132.9 39.7 8.4e-30 103.9 26.3 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1282 PF06930.12 PRP86205.1 - 0.41 10.4 15.5 0.16 11.7 6.0 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1282) Skp1 PF01466.19 PRP86206.1 - 2.2e-28 98.1 2.1 4.6e-28 97.1 2.1 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 PRP86206.1 - 2.8e-25 88.3 0.1 7e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain KIAA1430 PF13879.6 PRP86206.1 - 0.046 14.5 0.2 0.088 13.6 0.1 1.5 2 0 0 2 2 2 0 KIAA1430 homologue Myb_DNA-binding PF00249.31 PRP86206.1 - 0.19 12.0 0.7 22 5.3 0.3 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Choline_transpo PF04515.12 PRP86207.1 - 4.9e-90 302.0 29.5 4.9e-90 302.0 29.5 2.4 3 0 0 3 3 3 1 Plasma-membrane choline transporter SSP160 PF06933.11 PRP86207.1 - 0.0042 15.4 6.0 0.0067 14.7 6.0 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 TMEM154 PF15102.6 PRP86207.1 - 7.3 6.5 6.7 8.1 6.3 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family RasGEF PF00617.19 PRP86208.1 - 2.1e-33 116.0 0.0 4.9e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain V4R PF02830.18 PRP86208.1 - 7.8e-08 32.2 2.5 1.2e-06 28.5 0.3 2.4 2 0 0 2 2 2 2 V4R domain Brix PF04427.18 PRP86210.1 - 1.2e-39 136.5 0.0 1.6e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain Bd3614-deam PF14439.6 PRP86210.1 - 0.019 15.0 0.7 0.034 14.2 0.7 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Atg14 PF10186.9 PRP86210.1 - 0.073 12.2 0.0 0.073 12.2 0.0 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YL1 PF05764.13 PRP86210.1 - 1.4 8.9 12.3 0.17 12.0 3.6 2.1 2 0 0 2 2 2 0 YL1 nuclear protein Lactamase_B_2 PF12706.7 PRP86212.1 - 2.8e-26 92.3 0.0 4.6e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP86212.1 - 1.2e-10 41.7 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily X8 PF07983.13 PRP86213.1 - 1.7e-22 79.8 8.8 6.5e-11 42.8 0.2 2.5 2 0 0 2 2 2 2 X8 domain Glyco_hydro_17 PF00332.18 PRP86213.1 - 6.3e-06 26.0 0.1 1.8e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF3712 PF12505.8 PRP86214.1 - 7.2e-24 84.4 4.2 4.3e-16 59.3 0.1 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3712) LEA_2 PF03168.13 PRP86214.1 - 0.001 19.6 1.8 0.17 12.4 0.1 3.7 4 0 0 4 4 4 2 Late embryogenesis abundant protein Cation_ATPase_C PF00689.21 PRP86215.1 - 4.4e-43 147.1 0.5 4.4e-43 147.1 0.5 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PRP86215.1 - 1.1e-37 129.4 0.3 3.2e-37 127.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 PRP86215.1 - 6.6e-21 74.2 0.1 1.3e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PRP86215.1 - 4.8e-14 53.1 0.0 1e-13 52.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PRP86215.1 - 3.7e-12 45.8 0.0 1.1e-11 44.2 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PRP86215.1 - 0.002 17.9 0.1 0.0043 16.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EGF_2 PF07974.13 PRP86217.1 - 0.021 15.2 4.1 0.04 14.3 4.1 1.4 1 0 0 1 1 1 0 EGF-like domain PMSR PF01625.21 PRP86218.1 - 1.2e-56 191.1 0.2 1.8e-56 190.6 0.2 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF5127 PF17168.4 PRP86219.1 - 2.7e-51 174.6 2.3 3.9e-51 174.0 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 PRP86219.1 - 1.6e-48 164.7 0.0 2.1e-44 151.3 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF1793 PF08760.11 PRP86219.1 - 1.1e-35 123.6 4.0 2.3e-35 122.5 4.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 PRP86219.1 - 7.1e-20 70.4 0.2 1.8e-19 69.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) PAN_4 PF14295.6 PRP86219.1 - 5.5e-06 26.2 4.7 1.1e-05 25.2 4.7 1.5 1 0 0 1 1 1 1 PAN domain Glyco_hydr_116N PF12215.8 PRP86219.1 - 0.00062 19.4 0.2 0.0014 18.2 0.2 1.6 1 1 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term PAN_1 PF00024.26 PRP86219.1 - 0.0038 17.2 1.9 0.0079 16.1 1.9 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP86219.1 - 0.018 15.1 3.1 0.039 14.1 3.1 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_3 PF08277.12 PRP86219.1 - 0.16 11.8 2.0 0.34 10.7 2.0 1.5 1 0 0 1 1 1 0 PAN-like domain Ephrin_rec_like PF07699.13 PRP86220.1 - 4.1e-12 45.7 19.1 2e-08 33.9 7.7 5.1 4 1 1 5 5 5 3 Putative ephrin-receptor like CUB PF00431.20 PRP86220.1 - 1.6e-07 31.7 0.1 2.8e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 CUB domain TNFR_c6 PF00020.18 PRP86220.1 - 0.0011 19.3 25.6 0.0013 19.1 3.8 5.2 3 1 1 4 4 4 2 TNFR/NGFR cysteine-rich region PP2C PF00481.21 PRP86221.1 - 5.8e-55 186.7 0.0 1e-54 185.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Homeodomain PF00046.29 PRP86221.1 - 1e-06 28.4 1.6 1.6e-06 27.8 0.6 1.8 2 0 0 2 2 2 1 Homeodomain PP2C_2 PF13672.6 PRP86221.1 - 0.003 17.2 0.0 0.0083 15.8 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C LigB PF02900.18 PRP86222.1 - 7e-34 117.1 0.0 8.5e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LytR_C PF13399.6 PRP86222.1 - 0.064 14.3 0.0 0.47 11.5 0.0 2.1 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator CRAL_TRIO_2 PF13716.6 PRP86224.1 - 2.7e-19 69.7 0.6 5.8e-19 68.6 0.6 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 PRP86224.1 - 1.9e-15 56.9 0.0 7.6e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Macro domain CRAL_TRIO PF00650.20 PRP86224.1 - 1e-07 31.8 0.7 1.9e-07 30.9 0.7 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain TMEM156 PF15106.6 PRP86225.1 - 0.025 14.0 1.4 0.03 13.8 1.4 1.0 1 0 0 1 1 1 0 TMEM156 protein family FliX PF10768.9 PRP86225.1 - 0.2 12.2 10.9 0.24 11.9 10.6 1.3 1 1 0 1 1 1 0 Class II flagellar assembly regulator HOIP-UBA PF16678.5 PRP86225.1 - 0.21 11.6 8.6 2 8.4 8.6 2.1 1 1 0 1 1 1 0 HOIP UBA domain pair DUF3527 PF12043.8 PRP86225.1 - 2.2 7.8 7.7 2.4 7.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) Tropomyosin PF00261.20 PRP86227.1 - 0.0039 16.6 18.4 0.0054 16.1 18.4 1.1 1 0 0 1 1 1 1 Tropomyosin Bacillus_HBL PF05791.11 PRP86227.1 - 0.014 15.2 3.8 0.022 14.6 3.8 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) RasGAP_C PF03836.15 PRP86227.1 - 0.019 15.1 5.5 0.036 14.2 5.5 1.5 1 0 0 1 1 1 0 RasGAP C-terminus Tox-ODYAM1 PF15642.6 PRP86227.1 - 0.031 13.3 2.6 0.04 12.9 2.6 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus FapA PF03961.13 PRP86227.1 - 0.031 12.9 6.0 0.042 12.5 6.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 PRP86227.1 - 0.032 13.1 12.5 0.043 12.7 12.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 PRP86227.1 - 0.046 14.0 0.4 0.046 14.0 0.4 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HAUS-augmin3 PF14932.6 PRP86227.1 - 0.047 13.3 11.4 0.067 12.8 11.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fib_alpha PF08702.10 PRP86227.1 - 0.057 13.6 7.0 0.11 12.7 7.0 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FPP PF05911.11 PRP86227.1 - 0.069 11.3 13.0 0.088 11.0 13.0 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil AAA_11 PF13086.6 PRP86227.1 - 0.099 12.4 7.4 0.15 11.9 7.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4337 PF14235.6 PRP86227.1 - 0.12 12.5 4.5 0.2 11.8 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.19 PRP86227.1 - 0.15 10.0 3.1 0.17 9.8 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Het-C PF07217.11 PRP86227.1 - 0.19 10.2 1.6 0.25 9.8 1.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Ribosomal_L20 PF00453.18 PRP86227.1 - 0.2 11.8 4.2 0.28 11.3 3.6 1.6 1 1 0 1 1 1 0 Ribosomal protein L20 Atg14 PF10186.9 PRP86227.1 - 0.22 10.6 10.4 0.37 9.8 10.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 PRP86227.1 - 0.25 10.6 5.7 0.35 10.1 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 PRP86227.1 - 0.28 10.5 5.3 0.5 9.7 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 PRP86227.1 - 0.3 8.6 17.0 0.39 8.2 17.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 PRP86227.1 - 0.68 9.4 9.0 0.93 9.0 9.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.6 PRP86227.1 - 0.94 8.0 8.3 1.2 7.7 8.3 1.1 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 PRP86227.1 - 1.2 7.9 3.0 1.5 7.6 3.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_GPO PF05929.11 PRP86227.1 - 3.6 7.1 10.0 5.3 6.6 10.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.12 PRP86227.1 - 5.3 7.1 7.6 6.7 6.8 6.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 PRP86227.1 - 5.9 7.4 17.9 9.6 6.7 17.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region LIDHydrolase PF10230.9 PRP86228.1 - 5.7e-57 193.3 0.3 6.8e-57 193.0 0.3 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 PRP86228.1 - 4.1e-10 39.3 0.0 5.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP86228.1 - 5.9e-05 22.8 0.3 0.003 17.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold LCAT PF02450.15 PRP86228.1 - 0.032 13.4 0.1 0.065 12.4 0.1 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LRR_6 PF13516.6 PRP86229.1 - 8.3e-07 28.6 16.2 0.075 13.1 0.4 8.4 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 PRP86229.1 - 0.00011 22.2 8.9 5.6 7.9 0.2 7.9 8 0 0 8 8 8 1 Leucine Rich Repeat Carm_PH PF17888.1 PRP86229.1 - 0.021 15.2 0.1 0.046 14.1 0.1 1.5 1 0 0 1 1 1 0 Carmil pleckstrin homology domain VirD1 PF07328.11 PRP86229.1 - 0.041 13.9 0.5 0.21 11.5 0.1 2.4 4 0 0 4 4 4 0 T-DNA border endonuclease VirD1 TIR PF01582.20 PRP86229.1 - 0.043 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 TIR domain LRR_4 PF12799.7 PRP86229.1 - 0.26 11.8 17.2 2.5 8.6 0.1 6.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP86229.1 - 0.31 10.9 7.5 31 4.4 0.1 5.8 6 0 0 6 6 6 0 Leucine rich repeat SH3_1 PF00018.28 PRP86230.1 - 2.4e-21 75.1 0.9 1.5e-10 40.5 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 PRP86230.1 - 5e-21 74.3 1.6 1e-12 47.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 PRP86230.1 - 1.3e-18 66.5 0.0 4.3e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_4 PF06347.13 PRP86230.1 - 0.00011 22.0 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial SH3 domain Remorin_N PF03766.13 PRP86230.1 - 0.2 11.7 1.6 0.59 10.2 0.0 2.6 2 0 0 2 2 2 0 Remorin, N-terminal region CdiI_2 PF18593.1 PRP86230.1 - 2.4 8.9 4.5 59 4.4 0.1 3.3 2 1 1 3 3 3 0 CdiI immunity protein ubiquitin PF00240.23 PRP86231.1 - 1.5e-05 24.6 0.0 3.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family OTU PF02338.19 PRP86231.1 - 0.00018 22.0 0.0 0.0003 21.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Rad60-SLD PF11976.8 PRP86231.1 - 0.022 14.6 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.8 PRP86231.1 - 0.03 14.8 0.0 0.063 13.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Rep_N PF08724.10 PRP86233.1 - 0.022 14.5 1.3 0.06 13.1 1.3 1.7 1 0 0 1 1 1 0 Rep protein catalytic domain like DUF2456 PF10445.9 PRP86234.1 - 0.00061 19.8 0.1 0.00061 19.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) DUF4395 PF14340.6 PRP86235.1 - 1.3e-23 83.8 9.9 1.3e-23 83.8 9.9 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF4395) DUF4395 PF14340.6 PRP86236.1 - 5.1e-23 81.8 7.3 5.1e-23 81.8 7.3 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4395) VPS13_C PF16909.5 PRP86239.1 - 4.2e-59 199.3 0.5 3.2e-57 193.2 0.2 2.7 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 PRP86239.1 - 1.9e-51 175.0 0.1 2e-50 171.7 0.1 2.4 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 PRP86239.1 - 0.0003 21.1 0.0 0.0079 16.5 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 PRP86239.1 - 0.018 13.9 0.2 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cornichon PF03311.14 PRP86240.1 - 0.0023 18.3 0.2 0.0023 18.3 0.2 2.2 2 1 0 2 2 2 1 Cornichon protein Phage_holin_3_6 PF07332.11 PRP86240.1 - 1.2 9.2 7.6 24 5.0 0.0 2.2 1 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III AlbA_2 PF04326.14 PRP86241.1 - 0.0001 22.6 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Putative DNA-binding domain DND1_DSRM PF14709.7 PRP86241.1 - 0.0039 17.4 0.0 0.031 14.5 0.0 2.6 3 0 0 3 3 3 1 double strand RNA binding domain from DEAD END PROTEIN 1 4HBT PF03061.22 PRP86242.1 - 1.9e-06 28.1 0.0 3.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Carb_bind PF10645.9 PRP86243.1 - 8.1e-12 45.2 48.3 6.3e-07 29.5 14.2 5.2 4 1 1 5 5 5 4 Carbohydrate binding Thaumatin PF00314.17 PRP86243.1 - 3.2e-10 40.0 9.6 3.2e-10 40.0 9.6 5.0 2 2 0 3 3 3 1 Thaumatin family SDA1 PF05285.12 PRP86244.1 - 0.0012 18.3 10.9 0.0018 17.8 10.9 1.2 1 0 0 1 1 1 1 SDA1 PSCyt3 PF07627.11 PRP86244.1 - 0.28 11.5 0.2 0.28 11.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) GCR1_C PF12550.8 PRP86244.1 - 0.38 11.1 4.5 0.31 11.4 2.5 2.0 2 1 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Neur_chan_memb PF02932.16 PRP86244.1 - 0.64 10.0 5.0 0.9 9.5 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 PRP86244.1 - 1.2 8.5 5.6 1.4 8.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NARP1 PF12569.8 PRP86244.1 - 1.6 7.6 15.4 2.1 7.2 15.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 XRN_M PF17846.1 PRP86244.1 - 2 7.3 7.0 2.8 6.8 7.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 PRP86244.1 - 3.2 5.8 6.6 3.4 5.7 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.11 PRP86244.1 - 3.8 7.5 15.2 4.8 7.2 15.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 PRP86244.1 - 9 4.9 8.0 11 4.7 8.0 1.1 1 0 0 1 1 1 0 Presenilin YqaJ PF09588.10 PRP86245.1 - 1.8e-12 47.7 0.0 8e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain PPI_Ypi1 PF07491.11 PRP86247.1 - 0.024 14.5 0.2 0.035 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor RPA_interact_M PF14767.6 PRP86248.1 - 0.0051 17.3 2.9 0.0083 16.7 2.2 1.7 1 1 0 1 1 1 1 Replication protein A interacting middle AAA_23 PF13476.6 PRP86248.1 - 1.1 9.7 7.9 1.2 9.6 6.4 1.9 2 1 0 2 2 2 0 AAA domain adh_short PF00106.25 PRP86249.1 - 4e-40 137.4 0.0 5.7e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP86249.1 - 1.8e-26 93.2 0.0 2.5e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PRP86249.1 - 4.1e-05 23.2 0.1 6.9e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP86249.1 - 6.5e-05 22.9 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 PRP86249.1 - 7.7e-05 22.7 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 PRP86249.1 - 0.0017 17.8 0.1 0.0026 17.2 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 PRP86249.1 - 0.0024 17.5 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 PRP86249.1 - 0.014 14.4 0.1 0.026 13.5 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PRP86249.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain HECT PF00632.25 PRP86250.1 - 3.8e-61 207.3 0.0 8.6e-61 206.1 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.17 PRP86250.1 - 2.2e-15 56.2 23.6 8.2e-08 31.9 8.9 2.8 2 0 0 2 2 2 2 Zinc finger, ZZ type ArAE_1_C PF11728.8 PRP86250.1 - 8.8 6.3 7.8 1.2 9.1 0.2 3.0 2 1 2 4 4 4 0 Putative aromatic acid exporter C-terminal domain ICMT PF04140.14 PRP86251.1 - 1.5e-12 47.8 7.0 5.2e-12 46.0 2.7 2.6 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 PRP86251.1 - 4.8e-11 43.0 1.2 3.3e-09 37.1 0.5 2.5 2 0 0 2 2 2 1 Phospholipid methyltransferase Zip PF02535.22 PRP86251.1 - 0.026 13.8 0.2 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF1295 PF06966.12 PRP86251.1 - 0.067 12.7 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DctQ PF04290.12 PRP86251.1 - 0.08 12.9 3.3 5.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Cytokin-bind PF09265.10 PRP86251.1 - 0.096 12.1 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DHHC PF01529.20 PRP86251.1 - 0.88 9.7 4.7 0.98 9.5 0.3 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Pkinase_Tyr PF07714.17 PRP86252.1 - 9.3e-61 205.4 0.0 1.2e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86252.1 - 2e-49 168.4 0.0 2.7e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP86252.1 - 3.9e-14 52.5 0.0 8.1e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 PRP86252.1 - 0.00025 21.0 0.1 0.00063 19.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP86252.1 - 0.0022 17.0 0.0 0.0075 15.2 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP86252.1 - 0.12 11.1 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PRP86252.1 - 0.14 11.8 0.1 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Complex1_LYR PF05347.15 PRP86253.1 - 2e-06 27.7 0.3 3.7e-06 26.9 0.1 1.5 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Grg1 PF11034.8 PRP86254.1 - 7.9e-27 93.3 4.4 1.2e-26 92.7 4.4 1.2 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 TetR_C_14 PF17754.1 PRP86254.1 - 0.14 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 MftR C-terminal domain Pkinase_Tyr PF07714.17 PRP86255.1 - 5.4e-69 232.4 0.0 1.5e-68 230.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86255.1 - 4.3e-49 167.2 0.0 7.8e-49 166.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 PRP86255.1 - 2.3e-05 23.5 0.0 9.7e-05 21.5 0.0 1.8 1 1 0 1 1 1 1 Haspin like kinase domain dCache_1 PF02743.18 PRP86255.1 - 0.00045 20.1 1.0 0.00089 19.1 1.0 1.6 1 1 0 1 1 1 1 Cache domain Kdo PF06293.14 PRP86255.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP86255.1 - 0.01 14.7 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF418 PF04235.12 PRP86255.1 - 1.1 9.1 3.7 11 6.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF418) PRIMA1 PF16101.5 PRP86255.1 - 1.7 8.7 3.5 20 5.2 0.0 3.2 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF1282 PF06930.12 PRP86255.1 - 4.8 6.9 6.8 0.79 9.5 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) BORCS8 PF10167.9 PRP86256.1 - 6.3e-23 80.9 0.1 1e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 Pkinase PF00069.25 PRP86257.1 - 7.5e-59 199.2 0.0 9e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86257.1 - 2.2e-29 102.5 0.0 2.7e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP86257.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP86257.1 - 0.00054 20.0 1.0 0.00072 19.6 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP86257.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 PRP86257.1 - 0.046 13.3 0.0 0.13 11.8 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 PRP86257.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M16_M PF16187.5 PRP86258.1 - 1.9e-72 243.9 0.8 4e-71 239.6 0.8 2.5 1 1 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 PRP86258.1 - 2.6e-36 124.9 0.0 6.9e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PRP86258.1 - 2.9e-31 108.9 0.1 8.4e-17 61.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF3247 PF11607.8 PRP86258.1 - 0.0068 16.7 0.0 0.025 14.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3247) SpoIIIAC PF06686.11 PRP86258.1 - 0.15 12.2 0.3 0.51 10.5 0.1 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Zn_clus PF00172.18 PRP86260.1 - 0.011 15.9 16.9 0.016 15.3 16.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.7 PRP86260.1 - 0.064 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 PRP86260.1 - 0.082 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain Aldo_ket_red PF00248.21 PRP86261.1 - 5.8e-76 255.5 0.0 6.6e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family VWA_2 PF13519.6 PRP86262.1 - 7.4e-18 65.2 0.0 1.5e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP86262.1 - 8.6e-13 48.9 0.0 1.7e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PRP86262.1 - 1.5e-09 37.9 0.1 4.3e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.6 PRP86262.1 - 6.1e-09 35.6 6.3 6.1e-09 35.6 6.3 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP86262.1 - 4.1e-08 32.9 6.1 4.1e-08 32.9 6.1 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DUF1194 PF06707.11 PRP86262.1 - 0.022 14.0 0.0 0.078 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) Ku_N PF03731.15 PRP86262.1 - 0.026 14.3 0.1 0.39 10.4 0.1 2.3 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain VWA_CoxE PF05762.14 PRP86262.1 - 0.04 13.3 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 PRP86262.1 - 0.063 13.4 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus Kinocilin PF15033.6 PRP86263.1 - 0.078 12.6 1.3 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Kinocilin protein PhoLip_ATPase_C PF16212.5 PRP86263.1 - 1.2 8.8 11.2 0.052 13.3 2.7 2.0 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal LapA_dom PF06305.11 PRP86263.1 - 1.4 8.8 3.8 0.77 9.6 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PET PF06297.14 PRP86264.1 - 0.066 13.5 0.2 0.077 13.3 0.2 1.3 1 1 0 1 1 1 0 PET Domain Stanniocalcin PF03298.13 PRP86264.1 - 0.068 12.5 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Stanniocalcin family MerR-DNA-bind PF09278.11 PRP86265.1 - 0.098 13.2 0.2 0.23 12.0 0.2 1.6 1 0 0 1 1 1 0 MerR, DNA binding EF-hand_6 PF13405.6 PRP86266.1 - 6.3e-07 28.8 0.1 3.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 PRP86266.1 - 3.8e-05 23.0 0.0 0.00013 21.3 0.1 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PRP86266.1 - 4e-05 24.0 0.0 6.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP86266.1 - 8.4e-05 21.8 0.0 0.00082 18.8 0.0 2.2 2 0 0 2 2 2 1 EF hand Trypsin_2 PF13365.6 PRP86267.1 - 7.4e-28 98.3 0.0 1.4e-27 97.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PRP86267.1 - 4.3e-07 30.0 0.0 7.4e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S46 PF10459.9 PRP86267.1 - 0.0045 15.7 0.0 0.01 14.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase S46 Peptidase_C4 PF00863.19 PRP86267.1 - 0.012 15.0 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C4 Peptidase_S32 PF05579.13 PRP86267.1 - 0.024 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 CbiG_mid PF11761.8 PRP86268.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 1 1 2 2 2 0 Cobalamin biosynthesis central region SMC_N PF02463.19 PRP86269.1 - 2.1e-49 167.9 63.2 2.9e-30 105.4 0.0 4.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PRP86269.1 - 2.2e-22 79.6 1.3 1.3e-21 77.0 0.2 3.1 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 PRP86269.1 - 1.2e-14 54.8 12.4 1.2e-14 54.8 12.4 4.9 2 2 3 5 5 5 1 AAA ATPase domain AAA_21 PF13304.6 PRP86269.1 - 7.8e-10 39.0 23.3 1.5e-06 28.3 0.0 4.3 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PRP86269.1 - 3.1e-06 26.8 0.0 6.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 PRP86269.1 - 0.013 15.8 0.0 0.071 13.3 0.0 2.4 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF16 PF01519.16 PRP86269.1 - 0.013 16.0 4.7 0.013 16.0 4.7 8.4 5 1 3 8 8 8 0 Protein of unknown function DUF16 Ribosomal_S30 PF04758.14 PRP86269.1 - 6.9 7.0 8.0 12 6.2 5.2 3.1 2 0 0 2 2 2 0 Ribosomal protein S30 ADK PF00406.22 PRP86270.1 - 2.2e-48 164.2 0.0 5.1e-48 163.0 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PRP86270.1 - 8.7e-35 120.1 0.1 2.1e-34 118.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain Guanylate_cyc PF00211.20 PRP86270.1 - 1.6e-32 112.6 0.3 3.5e-32 111.5 0.3 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA_18 PF13238.6 PRP86270.1 - 5.8e-09 36.6 0.0 1.3e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PRP86270.1 - 2.2e-06 27.9 0.0 5.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PRP86270.1 - 0.0096 15.6 0.3 1.4 8.5 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.12 PRP86270.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma_reg_N PF13800.6 PRP86270.1 - 0.075 13.3 2.8 4.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TPR_16 PF13432.6 PRP86270.1 - 0.24 12.1 0.1 0.55 10.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4064 PF13273.6 PRP86270.1 - 2.8 8.3 6.4 33 4.8 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Myotub-related PF06602.14 PRP86271.1 - 3.6e-132 440.6 0.0 7.8e-132 439.5 0.0 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 PRP86271.1 - 4.3e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PRP86271.1 - 0.0018 18.3 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 PRP86271.1 - 0.0097 15.5 0.2 0.029 13.9 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase 3-PAP PF12578.8 PRP86271.1 - 0.02 14.6 3.3 0.081 12.7 0.0 3.0 3 0 0 3 3 3 0 Myotubularin-associated protein Gly-zipper_YMGG PF13441.6 PRP86272.1 - 0.0016 18.2 10.4 0.0024 17.5 10.4 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Diphtheria_T PF02764.14 PRP86272.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 Diphtheria toxin, T domain TctA PF01970.16 PRP86272.1 - 0.021 13.6 0.1 0.022 13.5 0.1 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Gly-zipper_Omp PF13488.6 PRP86272.1 - 0.025 14.6 16.3 0.059 13.4 16.3 1.6 1 1 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 PRP86272.1 - 0.17 12.2 1.9 0.29 11.4 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Bacteriocin_IIc PF10439.9 PRP86272.1 - 0.47 10.6 10.4 0.67 10.1 10.4 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.15 PRP86272.1 - 1.6 8.6 20.1 3 7.8 20.1 1.4 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 PRP86272.1 - 2.8 7.8 18.8 8.8 6.2 18.8 1.7 1 1 0 1 1 1 0 Glycine-zipper domain Period_C PF12114.8 PRP86273.1 - 2.6 7.6 11.5 3.8 7.1 11.5 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region BORCS8 PF10167.9 PRP86274.1 - 6.9e-17 61.4 0.1 8.7e-17 61.1 0.1 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 NCA2 PF08637.10 PRP86275.1 - 1.4e-69 234.5 1.7 1.4e-69 234.4 0.3 1.7 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Pkinase_Tyr PF07714.17 PRP86276.1 - 3e-15 56.2 0.2 1.6e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP86276.1 - 0.00088 18.7 0.2 0.03 13.7 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain MFS_1 PF07690.16 PRP86276.1 - 0.049 12.6 2.4 0.062 12.2 2.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2207 PF09972.9 PRP86276.1 - 0.06 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_S8 PF00082.22 PRP86277.1 - 1.3e-34 119.9 0.9 2.2e-34 119.1 0.9 1.3 1 0 0 1 1 1 1 Subtilase family DUF4215 PF13948.6 PRP86277.1 - 0.00046 20.6 4.1 0.00046 20.6 4.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) VWA_2 PF13519.6 PRP86278.1 - 1.8e-18 67.2 0.0 3.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP86278.1 - 2.5e-13 50.7 0.0 4.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.6 PRP86278.1 - 1.5e-11 44.0 12.2 1.5e-11 44.0 12.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) VWA_3 PF13768.6 PRP86278.1 - 1.6e-10 41.1 0.1 4.5e-10 39.7 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain Prok-RING_4 PF14447.6 PRP86278.1 - 1.5e-08 34.4 12.7 1.5e-08 34.4 12.7 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP86278.1 - 0.013 15.4 11.1 0.013 15.4 11.1 3.0 3 1 0 3 3 3 0 zinc-RING finger domain DUF1194 PF06707.11 PRP86278.1 - 0.014 14.6 0.0 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1194) Ku_N PF03731.15 PRP86278.1 - 0.019 14.7 0.4 0.75 9.5 0.1 2.3 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain VWA_CoxE PF05762.14 PRP86278.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Aldo_ket_red PF00248.21 PRP86279.1 - 6.3e-75 252.1 0.0 7.2e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PseudoU_synth_2 PF00849.22 PRP86280.1 - 6.2e-12 45.9 0.0 2.3e-11 44.0 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 PRP86280.1 - 6.6e-05 22.5 0.6 0.00022 20.9 0.5 2.0 1 1 1 2 2 2 1 S4 domain GCD14 PF08704.10 PRP86281.1 - 0.0067 16.1 0.2 0.0076 16.0 0.2 1.0 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MFS_1 PF07690.16 PRP86283.1 - 1.1e-29 103.5 29.0 1.1e-29 103.5 29.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 PRP86283.1 - 0.0016 16.8 0.1 0.0016 16.8 0.1 3.3 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family ATPase_gene1 PF09527.10 PRP86283.1 - 8.2 6.7 26.0 0.62 10.3 1.1 4.9 4 0 0 4 4 4 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter CAP PF00188.26 PRP86284.1 - 1.6e-21 77.4 8.3 2.5e-21 76.8 8.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pro-kuma_activ PF09286.11 PRP86285.1 - 1.6e-29 103.0 0.5 4.3e-29 101.6 0.3 1.8 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP86285.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Subtilase family AP1AR PF15745.5 PRP86286.1 - 0.069 12.8 0.1 0.082 12.5 0.1 1.0 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Synaphin PF05835.12 PRP86286.1 - 0.084 13.2 0.4 0.1 12.9 0.4 1.1 1 0 0 1 1 1 0 Synaphin protein Putative_PNPOx PF01243.20 PRP86287.1 - 2e-25 88.8 0.0 3.4e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 PRP86287.1 - 2.1e-20 72.5 3.1 4.3e-20 71.5 3.1 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 PRP86287.1 - 1.1e-05 25.9 0.1 2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 PRP86287.1 - 0.00028 20.5 0.0 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase like KdpC PF02669.15 PRP86287.1 - 0.0049 16.7 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 K+-transporting ATPase, c chain Grg1 PF11034.8 PRP86288.1 - 3.6e-20 72.0 7.3 9.9e-20 70.5 7.3 1.7 1 1 0 1 1 1 1 Glucose-repressible protein Grg1 ABC_membrane PF00664.23 PRP86289.1 - 1.2e-53 182.6 22.7 2.5e-28 99.5 7.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP86289.1 - 9.1e-49 165.5 0.0 6.8e-27 94.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PRP86289.1 - 1e-10 41.4 5.8 8.1e-06 25.4 1.5 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PRP86289.1 - 1.5e-06 28.3 0.5 0.015 15.4 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP86289.1 - 2.8e-06 27.3 0.5 0.032 14.1 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_29 PF13555.6 PRP86289.1 - 5.9e-06 25.9 1.0 0.043 13.6 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP86289.1 - 2.6e-05 24.7 0.2 0.41 11.0 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 PRP86289.1 - 2.7e-05 24.8 0.4 0.24 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 PRP86289.1 - 0.00064 19.6 4.8 1.5 8.5 0.1 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PRP86289.1 - 0.0012 19.1 2.9 1.2 9.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PRP86289.1 - 0.0012 18.4 0.1 0.2 11.1 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 PRP86289.1 - 0.0019 17.4 0.2 0.41 9.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 PRP86289.1 - 0.0058 16.4 0.1 0.76 9.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA PF00004.29 PRP86289.1 - 0.0091 16.4 1.1 0.6 10.5 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 PRP86289.1 - 0.012 14.9 0.1 0.57 9.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_PrkA PF08298.11 PRP86289.1 - 0.013 14.4 0.1 0.34 9.8 0.0 2.4 2 0 0 2 2 2 0 PrkA AAA domain T2SSE PF00437.20 PRP86289.1 - 0.073 12.1 0.1 1.8 7.5 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_5 PF07728.14 PRP86289.1 - 0.074 13.1 2.9 23 5.0 0.1 4.1 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 PRP86289.1 - 0.075 13.1 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_15 PF13175.6 PRP86289.1 - 0.087 12.5 0.8 6.5 6.3 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 PRP86289.1 - 0.11 12.2 0.5 26 4.5 0.2 2.9 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 PRP86289.1 - 0.14 12.4 0.5 4.8 7.4 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 PRP86289.1 - 0.2 10.8 3.0 3.9 6.6 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain RNase_3_N PF18497.1 PRP86289.1 - 0.21 11.8 0.9 27 5.0 0.0 3.1 3 0 0 3 3 2 0 Ribonuclease III N-terminal domain cobW PF02492.19 PRP86289.1 - 0.27 10.8 1.2 13 5.3 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 PRP86289.1 - 0.69 10.0 6.6 6.5 6.8 0.3 2.8 3 0 0 3 3 2 0 Dynamin family DUF4191 PF13829.6 PRP86289.1 - 1.8 7.8 5.4 1.3 8.3 3.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) Arf PF00025.21 PRP86292.1 - 6e-62 208.2 0.0 6.6e-62 208.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PRP86292.1 - 1.2e-12 47.8 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP86292.1 - 3.6e-12 46.5 0.0 5.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PRP86292.1 - 2.5e-09 36.8 0.0 4.1e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PRP86292.1 - 5.9e-08 32.4 0.0 7.3e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PRP86292.1 - 1.9e-07 30.7 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP86292.1 - 0.00045 20.3 0.0 0.00063 19.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP86292.1 - 0.0039 16.7 0.1 0.011 15.3 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 PRP86292.1 - 0.027 14.1 0.0 3.7 7.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 PRP86292.1 - 0.12 12.1 0.1 2.3 7.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Glyco_transf_34 PF05637.12 PRP86293.1 - 7.3e-39 133.9 2.2 9e-39 133.6 2.2 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Arrestin_C PF02752.22 PRP86294.1 - 8.8e-20 71.5 0.0 1.4e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PRP86294.1 - 8.7e-14 51.8 0.0 2.3e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 PRP86294.1 - 0.0041 16.4 0.0 0.034 13.3 0.0 2.7 2 1 1 3 3 3 1 Rgp1 7TMR-HDED PF07697.11 PRP86294.1 - 0.051 13.7 7.7 5.1 7.1 2.7 3.9 1 1 0 2 2 2 0 7TM-HD extracellular Bep_C_terminal PF17841.1 PRP86294.1 - 0.1 12.8 0.0 2.3 8.5 0.0 2.8 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) Lant_dehydr_C PF14028.6 PRP86294.1 - 0.11 12.1 0.6 0.82 9.2 0.1 2.2 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF2605 PF10792.9 PRP86294.1 - 0.13 12.2 0.2 0.5 10.3 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) RTX_C PF08339.10 PRP86294.1 - 0.21 11.7 4.9 0.14 12.2 0.2 2.8 3 1 1 4 4 4 0 RTX C-terminal domain PilJ PF13675.6 PRP86294.1 - 1.1 9.3 5.0 4.8 7.3 0.1 3.0 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.12 PRP86294.1 - 1.3 9.0 10.0 0.54 10.3 3.9 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SET PF00856.28 PRP86296.1 - 6e-12 46.3 0.1 4e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 PRP86296.1 - 0.014 15.5 1.0 0.014 15.5 1.0 2.3 3 0 0 3 3 3 0 MYND finger Glyco_transf_34 PF05637.12 PRP86297.1 - 7.4e-38 130.6 2.0 7.4e-38 130.6 2.0 1.5 2 0 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family Trypan_PARP PF05887.11 PRP86297.1 - 0.33 10.9 18.6 0.66 10.0 18.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RasGAP PF00616.19 PRP86298.1 - 4.4e-33 114.7 0.4 1.2e-32 113.3 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF547 PF04784.14 PRP86298.1 - 7.2e-26 90.6 0.0 2.3e-25 89.0 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF547 C2 PF00168.30 PRP86298.1 - 0.00062 20.0 0.0 0.0022 18.3 0.0 2.0 1 0 0 1 1 1 1 C2 domain Ank_4 PF13637.6 PRP86299.1 - 9.2e-44 147.3 0.9 2.7e-12 46.9 0.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86299.1 - 6.8e-42 142.0 0.0 5.4e-14 52.5 0.0 4.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PRP86299.1 - 1.3e-36 123.4 0.0 1.8e-06 28.1 0.0 6.3 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 PRP86299.1 - 1.2e-30 105.1 0.0 2.7e-07 30.7 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP86299.1 - 1.5e-28 95.7 0.0 0.00072 19.8 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat HEM4 PF02602.15 PRP86299.1 - 0.053 12.9 0.1 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Nitro_FeMo-Co PF02579.17 PRP86299.1 - 0.094 13.1 0.1 6.6 7.1 0.0 2.9 2 1 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Apq12 PF12716.7 PRP86301.1 - 0.28 11.1 1.7 9.6 6.2 0.1 2.4 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis FUN14 PF04930.15 PRP86302.1 - 2.7e-22 79.0 2.5 4.7e-22 78.2 2.5 1.4 1 0 0 1 1 1 1 FUN14 family Rif1_N PF12231.8 PRP86303.1 - 1.4e-36 126.3 1.1 5.8e-36 124.3 0.1 2.3 2 1 0 2 2 2 1 Rap1-interacting factor 1 N terminal adh_short PF00106.25 PRP86303.1 - 4e-35 121.1 0.1 6.7e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP86303.1 - 4.9e-29 101.5 0.1 9.7e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Grg1 PF11034.8 PRP86303.1 - 5.5e-27 93.8 6.2 5.5e-27 93.8 6.2 2.1 2 0 0 2 2 2 1 Glucose-repressible protein Grg1 KR PF08659.10 PRP86303.1 - 1.5e-06 28.3 0.1 3.5e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP86303.1 - 0.00091 19.2 0.2 0.0023 17.8 0.2 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PRP86303.1 - 0.0021 17.6 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 PRP86303.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Sec7_N PF12783.7 PRP86303.1 - 0.23 11.4 1.4 7.6 6.4 0.0 3.7 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Myosin_head PF00063.21 PRP86304.1 - 1.9e-221 736.9 0.4 3.2e-123 412.3 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) ABC_tran PF00005.27 PRP86304.1 - 0.067 13.7 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 PRP86304.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MIG-14_Wnt-bd PF06664.12 PRP86305.1 - 1.9e-65 221.0 36.0 1.9e-65 221.0 36.0 1.7 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Ac76 PF05814.11 PRP86305.1 - 0.052 13.6 0.2 0.052 13.6 0.2 3.9 4 0 0 4 4 4 0 Orf76 (Ac76) GET2 PF08690.10 PRP86305.1 - 2 8.0 3.3 0.92 9.1 0.9 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 DUF3493 PF11998.8 PRP86305.1 - 3.1 8.0 9.3 2.3 8.5 3.9 2.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 RSN1_7TM PF02714.15 PRP86306.1 - 3.3e-52 177.5 30.4 6.2e-52 176.6 30.4 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate adh_short PF00106.25 PRP86306.1 - 3.1e-36 124.7 0.0 4.8e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RSN1_TM PF13967.6 PRP86306.1 - 2.1e-29 102.3 1.0 7.1e-29 100.6 0.4 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport adh_short_C2 PF13561.6 PRP86306.1 - 5.1e-21 75.3 0.0 7.9e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PHM7_cyt PF14703.6 PRP86306.1 - 7.1e-17 62.2 0.0 1.2e-16 61.4 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter KR PF08659.10 PRP86306.1 - 3.5e-07 30.3 0.1 7.4e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP86306.1 - 3.7e-06 27.0 0.1 6.4e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PRP86306.1 - 0.00075 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PRP86306.1 - 0.0027 17.3 0.1 0.0046 16.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 PRP86306.1 - 0.078 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain PRK PF00485.18 PRP86308.1 - 1.8e-47 161.7 0.2 2.4e-47 161.2 0.2 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 PRP86308.1 - 0.00021 21.0 0.1 0.21 11.3 0.1 2.1 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_18 PF13238.6 PRP86308.1 - 0.0003 21.4 0.0 0.00052 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP86308.1 - 0.0028 17.0 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Cytidylate_kin PF02224.18 PRP86308.1 - 0.016 15.0 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 PRP86308.1 - 0.029 14.8 0.1 7.8 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PRP86308.1 - 0.042 12.9 0.1 0.08 12.0 0.0 1.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Glycos_transf_2 PF00535.26 PRP86309.1 - 3.4e-33 114.8 0.0 4.5e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PRP86309.1 - 5.9e-07 29.6 0.0 8.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 PRP86309.1 - 0.00022 21.6 0.0 0.00029 21.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_tranf_2_2 PF10111.9 PRP86309.1 - 0.0012 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Guanylate_cyc PF00211.20 PRP86310.1 - 4.3e-64 215.5 0.1 1.9e-31 109.1 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 PRP86311.1 - 5.3e-90 300.0 0.0 2.3e-38 131.7 0.0 3.3 3 0 0 3 3 3 3 Adenylate and Guanylate cyclase catalytic domain CRAL_TRIO PF00650.20 PRP86312.1 - 2.7e-35 121.5 0.0 3.5e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PRP86312.1 - 1.7e-06 28.3 0.0 2.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP86312.1 - 0.00022 21.4 0.3 0.00099 19.3 0.3 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain STAS PF01740.21 PRP86312.1 - 0.0043 16.7 0.0 0.0074 15.9 0.0 1.4 1 1 0 1 1 1 1 STAS domain Abhydrolase_3 PF07859.13 PRP86313.1 - 3.1e-15 56.6 0.0 4.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PRP86313.1 - 0.00058 18.8 0.0 0.00094 18.1 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Apolipoprotein PF01442.18 PRP86314.1 - 1.9e-08 34.4 68.3 4e-05 23.6 36.1 3.2 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 PRP86314.1 - 7e-06 26.6 72.2 0.1 13.2 8.3 6.0 1 1 5 6 6 6 5 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 PRP86314.1 - 0.002 18.6 107.5 55 4.4 23.8 7.3 1 1 2 3 3 3 0 YtxH-like protein NYD-SP28_assoc PF14775.6 PRP86314.1 - 0.0045 17.1 1.0 0.0045 17.1 1.0 3.0 2 1 0 2 2 2 1 Sperm tail C-terminal domain DUF2892 PF11127.8 PRP86315.1 - 0.044 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) Epimerase PF01370.21 PRP86316.1 - 8.6e-20 71.2 0.1 4e-19 69.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PRP86316.1 - 3.6e-14 52.9 0.5 1.6e-10 40.9 0.2 2.3 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 PRP86316.1 - 7.5e-14 52.0 0.3 7.5e-14 52.0 0.3 1.7 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PRP86316.1 - 1.4e-09 37.3 0.1 9.7e-07 28.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PRP86316.1 - 9.7e-09 35.1 0.0 1.4e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PRP86316.1 - 5.8e-08 32.2 0.2 3.5e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain TrkA_N PF02254.18 PRP86316.1 - 5.6e-06 26.6 0.1 1.8e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 PRP86316.1 - 0.0001 22.5 0.1 0.00019 21.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 PRP86316.1 - 0.00012 21.6 0.1 0.00021 20.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP86316.1 - 0.0002 21.3 0.2 0.00043 20.2 0.2 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 PRP86316.1 - 0.00097 18.4 0.1 0.002 17.4 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_2 PF03446.15 PRP86316.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 PRP86316.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.15 PRP86316.1 - 0.026 13.7 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.20 PRP86316.1 - 0.091 12.9 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 PRP86316.1 - 0.12 12.8 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Apolipoprotein PF01442.18 PRP86318.1 - 2.2e-12 47.3 159.5 2.8e-05 24.1 36.0 5.2 1 1 5 6 6 6 5 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 PRP86318.1 - 1.6e-06 28.6 125.8 0.15 12.7 7.7 10.3 1 1 7 10 10 10 8 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 PRP86318.1 - 0.0073 16.8 11.0 0.0073 16.8 11.0 13.1 2 2 9 11 11 11 5 YtxH-like protein FHA PF00498.26 PRP86319.1 - 0.029 14.7 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 FHA domain Yop-YscD_cpl PF16697.5 PRP86319.1 - 0.13 12.6 0.2 0.2 12.0 0.2 1.2 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain WD40 PF00400.32 PRP86320.1 - 1e-08 35.7 7.0 0.00069 20.4 0.7 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat Ras PF00071.22 PRP86321.1 - 2.1e-58 196.5 0.1 4.8e-58 195.3 0.1 1.7 1 0 0 1 1 1 1 Ras family PUL PF08324.11 PRP86321.1 - 3.6e-40 138.0 3.8 5.2e-40 137.4 3.8 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 PRP86321.1 - 3e-37 126.0 23.0 1.6e-06 28.7 0.0 8.5 9 0 0 9 9 8 7 WD domain, G-beta repeat PFU PF09070.11 PRP86321.1 - 8e-34 116.3 0.9 1.9e-33 115.1 0.9 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Roc PF08477.13 PRP86321.1 - 1.6e-20 73.5 0.0 6e-20 71.6 0.0 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP86321.1 - 2.6e-10 40.0 0.0 4.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP86321.1 - 1.6e-06 27.8 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain BBS2_Mid PF14783.6 PRP86321.1 - 6.9e-05 22.8 0.0 0.78 9.8 0.0 3.4 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region RsgA_GTPase PF03193.16 PRP86321.1 - 0.00035 20.5 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP86321.1 - 0.031 14.4 0.1 0.083 13.0 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase HEAT_2 PF13646.6 PRP86321.1 - 0.038 14.4 0.0 0.16 12.4 0.0 1.9 1 1 0 1 1 1 0 HEAT repeats Arm PF00514.23 PRP86321.1 - 0.14 12.2 0.4 20 5.4 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat MTHFR PF02219.17 PRP86322.1 - 1.7e-116 388.6 0.0 2.3e-116 388.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Bacillus_HBL PF05791.11 PRP86323.1 - 4.6e-05 23.3 12.0 4.6e-05 23.3 12.0 7.5 2 2 7 10 10 10 2 Bacillus haemolytic enterotoxin (HBL) CAP PF00188.26 PRP86324.1 - 2e-15 57.7 4.9 4e-15 56.8 4.9 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MSA-2c PF12238.8 PRP86324.1 - 8.1 6.4 11.0 17 5.4 11.0 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c CAP PF00188.26 PRP86325.1 - 5.3e-18 66.1 4.9 7e-18 65.7 4.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Tmemb_14 PF03647.13 PRP86326.1 - 2.1e-19 70.0 15.9 2.6e-19 69.7 15.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Pyridoxal_deC PF00282.19 PRP86327.1 - 3.5e-78 262.9 0.0 5.1e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 PRP86327.1 - 7.2e-07 28.5 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V zf_UBZ PF18439.1 PRP86327.1 - 0.15 11.7 0.6 0.32 10.6 0.6 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger GMC_oxred_N PF00732.19 PRP86329.1 - 7.8e-23 81.3 0.0 1.3e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP86329.1 - 2.1e-09 38.1 0.0 4.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PRP86329.1 - 0.014 15.6 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PARG_cat PF05028.14 PRP86330.1 - 4.6e-58 197.1 0.0 6.3e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) X8 PF07983.13 PRP86331.1 - 1.3e-10 41.8 3.3 1.3e-10 41.8 3.3 2.3 2 0 0 2 2 2 1 X8 domain Carb_bind PF10645.9 PRP86331.1 - 3.1e-09 36.9 37.7 4.2e-06 26.9 17.1 4.1 3 1 1 4 4 4 3 Carbohydrate binding Glyco_hydro_72 PF03198.14 PRP86331.1 - 2.1e-06 27.2 0.1 7.5e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 PRP86331.1 - 0.013 15.0 0.1 0.98 8.8 0.0 2.4 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 PRP86331.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Glyco_hydro_2_C PF02836.17 PRP86331.1 - 0.061 12.4 0.0 0.24 10.5 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DEC-1_N PF04625.13 PRP86331.1 - 1.9 7.4 7.0 0.46 9.5 1.0 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region SLD5_C PF16922.5 PRP86332.1 - 2.4e-14 53.3 0.4 3.9e-14 52.6 0.4 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 PRP86332.1 - 7.7e-05 23.1 1.0 0.00018 21.9 1.0 1.7 1 0 0 1 1 1 1 GINS complex protein Exonuc_VII_L PF02601.15 PRP86332.1 - 0.2 11.2 2.0 0.23 11.0 2.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SNF2_N PF00176.23 PRP86333.1 - 1.6e-61 208.0 0.3 3e-61 207.1 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP86333.1 - 1.3e-17 64.2 0.0 4.8e-17 62.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 PRP86333.1 - 1.3e-12 47.4 3.2 1.8e-07 31.0 0.7 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 PRP86333.1 - 8.6e-09 35.6 0.0 8.6e-09 35.6 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PRP86333.1 - 3.4e-05 23.7 0.0 7.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SIR2 PF02146.17 PRP86334.1 - 9.8e-42 142.9 0.2 1.9e-41 141.9 0.2 1.4 1 1 0 1 1 1 1 Sir2 family GST_N_2 PF13409.6 PRP86335.1 - 1.3e-17 63.8 0.1 4.2e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP86335.1 - 1.2e-11 44.5 0.0 2.8e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP86335.1 - 9.6e-09 35.3 0.0 1.7e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP86335.1 - 0.00048 20.3 0.3 0.0016 18.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP86335.1 - 0.021 15.2 0.2 0.35 11.3 0.2 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PilJ PF13675.6 PRP86335.1 - 0.19 11.8 0.0 0.43 10.6 0.0 1.6 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term GST_N_2 PF13409.6 PRP86336.1 - 5.4e-17 61.9 0.0 1.5e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP86336.1 - 2e-11 43.7 0.1 5e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP86336.1 - 6.8e-09 35.8 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP86336.1 - 0.00098 19.3 0.1 0.0025 18.0 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP86336.1 - 0.009 16.4 0.1 0.13 12.7 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF973 PF06157.11 PRP86337.1 - 0.029 13.4 3.0 0.051 12.6 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF996 PF06195.13 PRP86337.1 - 1.7 9.0 11.5 5.9 7.2 4.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF996) DUF373 PF04123.13 PRP86337.1 - 8 5.8 13.7 1.6 8.1 6.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) MS_channel PF00924.18 PRP86338.1 - 9.9e-18 64.4 1.7 1.5e-17 63.8 1.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 PRP86338.1 - 0.0016 17.8 1.2 0.19 11.4 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP86338.1 - 0.0019 18.0 1.3 2.9 8.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PRP86338.1 - 0.064 12.8 1.5 0.096 12.2 0.3 1.9 2 0 0 2 2 2 0 EF hand Poxvirus_B22R_N PF13169.6 PRP86338.1 - 0.31 11.6 1.4 33 5.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus B22R protein N-terminal zf-C2H2_4 PF13894.6 PRP86339.1 - 0.011 16.6 4.3 0.03 15.2 4.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger FYVE PF01363.21 PRP86339.1 - 0.031 14.4 0.7 0.057 13.6 0.7 1.3 1 0 0 1 1 1 0 FYVE zinc finger Planc_extracel PF07595.12 PRP86339.1 - 0.041 13.7 0.5 0.041 13.7 0.5 2.6 3 0 0 3 3 3 0 Planctomycete extracellular zf_C2H2_ZHX PF18387.1 PRP86339.1 - 0.19 11.4 1.1 0.37 10.4 1.1 1.5 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 PRP86339.1 - 1.1 9.9 4.0 2.2 8.9 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type DNA_pol3_finger PF17657.1 PRP86340.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha subunit finger domain YdjM PF04307.14 PRP86341.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase zf-B_box PF00643.24 PRP86343.1 - 4e-08 33.3 4.2 4e-08 33.3 4.2 2.9 2 1 0 2 2 2 1 B-box zinc finger MATH PF00917.26 PRP86343.1 - 4.4e-06 26.8 0.1 1.1e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 MATH domain zf-RING_2 PF13639.6 PRP86343.1 - 0.00011 22.5 18.2 0.00031 21.0 18.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP86343.1 - 0.00038 20.3 16.0 0.00038 20.3 16.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP86343.1 - 0.00056 19.7 18.0 0.0013 18.5 18.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 PRP86343.1 - 0.13 12.1 0.0 0.77 9.6 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.25 PRP86343.1 - 0.24 11.3 19.0 0.64 9.9 19.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PRP86343.1 - 1.7 8.3 11.3 4.5 7.0 11.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 PRP86343.1 - 1.9 8.5 16.9 4.8 7.2 16.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Peptidase_C1 PF00112.23 PRP86345.1 - 1.6e-31 110.1 4.4 3.8e-31 108.9 4.4 1.6 1 0 0 1 1 1 1 Papain family cysteine protease PAN_4 PF14295.6 PRP86345.1 - 4e-22 77.9 62.0 1.1e-07 31.6 2.5 8.1 8 1 0 8 8 8 4 PAN domain PAN_1 PF00024.26 PRP86345.1 - 1.7e-19 69.5 24.7 7.4e-05 22.6 2.1 5.0 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.11 PRP86345.1 - 1.8e-05 24.7 34.8 0.42 10.7 2.4 5.1 4 0 0 4 4 4 4 PAN-like domain MANEC PF07502.14 PRP86345.1 - 2.6 8.4 26.7 5.1 7.4 1.5 4.9 4 0 0 4 4 4 0 MANEC domain ABC_tran PF00005.27 PRP86346.1 - 8.7e-50 168.8 0.0 1.8e-26 93.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 PRP86346.1 - 1.2e-46 159.6 23.5 1.2e-27 97.3 9.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 PRP86346.1 - 1.2e-13 51.0 0.0 0.00034 20.1 0.1 4.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PRP86346.1 - 6.8e-07 29.3 0.1 0.00098 19.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP86346.1 - 3.1e-06 27.2 2.1 0.021 14.9 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PRP86346.1 - 5.4e-06 26.9 0.3 0.026 14.9 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 PRP86346.1 - 1.9e-05 24.3 0.0 0.24 11.2 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF87 PF01935.17 PRP86346.1 - 0.0015 18.6 8.4 0.14 12.3 0.1 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_23 PF13476.6 PRP86346.1 - 0.0025 18.4 1.4 3.3 8.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 PRP86346.1 - 0.0051 17.1 1.8 1.1 9.6 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 PRP86346.1 - 0.0052 16.3 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MeaB PF03308.16 PRP86346.1 - 0.0062 15.6 0.1 0.67 8.9 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 PRP86346.1 - 0.0074 15.5 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) T2SSE PF00437.20 PRP86346.1 - 0.0091 15.1 0.0 0.77 8.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 PRP86346.1 - 0.0097 16.3 0.0 1.4 9.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ATP_bind_1 PF03029.17 PRP86346.1 - 0.011 15.6 1.8 1.5 8.5 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 PRP86346.1 - 0.012 15.6 5.6 15 5.5 0.1 4.0 4 0 0 4 4 4 0 NTPase AAA_PrkA PF08298.11 PRP86346.1 - 0.014 14.3 0.1 0.11 11.4 0.1 2.0 2 0 0 2 2 2 0 PrkA AAA domain KAP_NTPase PF07693.14 PRP86346.1 - 0.018 14.3 0.1 0.29 10.3 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_30 PF13604.6 PRP86346.1 - 0.02 14.6 0.0 6.7 6.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 PRP86346.1 - 0.025 14.4 3.4 7.8 6.2 0.1 3.8 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 PRP86346.1 - 0.028 14.6 0.4 17 5.6 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 PRP86346.1 - 0.032 14.6 0.5 4.4 7.7 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 PRP86346.1 - 0.075 12.4 0.2 7 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 PRP86346.1 - 0.078 12.6 0.4 1 8.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 PRP86346.1 - 0.086 11.9 0.2 0.96 8.4 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) IstB_IS21 PF01695.17 PRP86346.1 - 0.12 12.1 0.2 23 4.7 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 PRP86346.1 - 0.2 11.7 10.9 0.32 11.1 0.8 2.9 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.12 PRP86346.1 - 0.28 11.1 2.7 1.7 8.6 0.1 2.7 3 0 0 3 3 2 0 NACHT domain SUI1 PF01253.22 PRP86347.1 - 3.8e-21 75.4 0.3 5.7e-21 74.8 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Acetyltransf_3 PF13302.7 PRP86348.1 - 3.1e-18 66.8 0.0 4.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP86348.1 - 2.9e-05 23.9 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 PRP86348.1 - 0.00016 21.8 0.0 0.00038 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Cyt-b5 PF00173.28 PRP86349.1 - 2e-13 50.3 0.0 3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Alpha-amylase PF00128.24 PRP86350.1 - 2.2e-20 73.5 0.3 4.1e-19 69.3 0.0 2.7 2 1 0 2 2 2 1 Alpha amylase, catalytic domain CBM_48 PF02922.18 PRP86350.1 - 5.3e-10 39.5 0.0 4.3e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3459 PF11941.8 PRP86350.1 - 1.8e-06 28.2 0.0 4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Malt_amylase_C PF16657.5 PRP86350.1 - 0.00036 20.6 0.0 0.00077 19.5 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 PRP86350.1 - 0.2 10.7 0.5 1.4 7.9 0.0 2.3 2 1 0 3 3 3 0 Glycogen debranching enzyme, glucanotransferase domain DUF3185 PF11381.8 PRP86352.1 - 0.0089 16.0 0.3 0.025 14.6 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3185) DUF3188 PF11384.8 PRP86352.1 - 0.086 12.6 1.5 0.22 11.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Kinesin PF00225.23 PRP86354.1 - 5.8e-113 377.2 0.3 5.8e-113 377.2 0.3 3.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 PRP86354.1 - 3.9e-26 91.8 0.0 3.9e-26 91.8 0.0 3.5 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 PRP86354.1 - 0.097 13.0 0.3 0.097 13.0 0.3 5.5 3 1 2 5 5 5 0 Kinesin-associated microtubule-binding zf-nanos PF05741.13 PRP86354.1 - 0.47 10.7 2.1 53 4.2 0.5 3.5 3 0 0 3 3 3 0 Nanos RNA binding domain SET PF00856.28 PRP86355.1 - 1.3e-24 87.5 1.8 1.4e-23 84.1 0.3 2.7 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 PRP86355.1 - 8.3e-18 65.0 7.6 2.4e-17 63.6 5.5 2.5 2 0 0 2 2 2 1 Pre-SET motif AWS PF17907.1 PRP86355.1 - 2.9 8.0 14.5 0.15 12.1 4.4 2.9 2 0 0 2 2 2 0 AWS domain APH PF01636.23 PRP86357.1 - 6.6e-18 65.5 0.1 7.6e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family JmjC PF02373.22 PRP86357.1 - 2e-11 44.3 1.6 3.2e-05 24.3 0.0 3.3 3 0 0 3 3 3 2 JmjC domain, hydroxylase Cupin_8 PF13621.6 PRP86357.1 - 4.9e-11 42.8 0.7 5.5e-10 39.4 0.7 2.9 1 1 1 2 2 2 1 Cupin-like domain F-box-like PF12937.7 PRP86357.1 - 3.5e-05 23.6 0.1 9.7e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like CENP-Q PF13094.6 PRP86357.1 - 0.032 14.5 2.2 9.1 6.5 0.0 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Pkinase_Tyr PF07714.17 PRP86359.1 - 4.5e-70 235.9 0.0 7.2e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86359.1 - 1.6e-52 178.5 0.0 3.1e-52 177.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain dCache_1 PF02743.18 PRP86359.1 - 2.9e-05 24.0 0.6 6.5e-05 22.8 0.6 1.7 1 1 0 1 1 1 1 Cache domain Kdo PF06293.14 PRP86359.1 - 0.00026 20.4 0.0 0.00053 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP86359.1 - 0.00055 19.0 0.0 0.0015 17.6 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP86359.1 - 0.0016 17.3 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP86359.1 - 0.012 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Kinase-like HemY_N PF07219.13 PRP86359.1 - 0.016 15.4 3.5 13 6.0 0.8 3.5 3 0 0 3 3 3 0 HemY protein N-terminus DUF2976 PF11190.8 PRP86359.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF5383 PF17355.2 PRP86359.1 - 0.82 10.0 3.2 7 7.0 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Shisa PF13908.6 PRP86359.1 - 9.6 6.4 6.7 1.2 9.3 0.0 2.5 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Glyco_hydro_77 PF02446.17 PRP86360.1 - 2.2e-147 491.7 1.5 2.9e-147 491.3 1.5 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase FH2 PF02181.23 PRP86361.1 - 1.3e-88 297.7 0.2 1.7e-87 293.9 0.0 2.2 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 PRP86361.1 - 7.5e-24 84.4 3.9 7.5e-24 84.4 3.9 2.7 2 1 1 3 3 3 1 Diaphanous FH3 Domain Transposase_1 PF01359.18 PRP86361.1 - 0.019 14.8 1.1 0.055 13.3 0.2 2.3 2 0 0 2 2 2 0 Transposase (partial DDE domain) VGLL4 PF15245.6 PRP86361.1 - 0.049 13.7 0.7 0.17 12.0 0.7 1.9 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Histidinol_dh PF00815.20 PRP86361.1 - 0.061 12.3 0.7 0.12 11.4 0.7 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase Drf_GBD PF06371.13 PRP86361.1 - 0.063 12.8 0.6 0.2 11.2 0.6 1.8 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain GGDEF_2 PF17853.1 PRP86361.1 - 0.1 12.9 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 GGDEF-like domain DUF948 PF06103.11 PRP86361.1 - 0.19 12.0 0.7 3.3 8.0 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TBCA PF02970.16 PRP86361.1 - 2.4 8.5 9.6 0.23 11.8 2.9 2.7 2 0 0 2 2 2 0 Tubulin binding cofactor A Trehalase PF01204.18 PRP86361.1 - 3.6 6.3 7.0 0.16 10.8 1.0 1.7 2 0 0 2 2 2 0 Trehalase SMN PF06003.12 PRP86361.1 - 9 5.5 15.1 7.3 5.8 12.8 1.9 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) RPEL PF02755.15 PRP86362.1 - 8.2e-09 34.9 0.9 0.0003 20.4 0.1 2.9 2 0 0 2 2 2 2 RPEL repeat SrfB PF07520.11 PRP86364.1 - 0.13 10.1 0.0 0.15 9.9 0.0 1.0 1 0 0 1 1 1 0 Virulence factor SrfB EamA PF00892.20 PRP86365.1 - 5.5e-09 36.3 43.8 1.3e-05 25.4 15.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family SLATT_1 PF18181.1 PRP86365.1 - 0.91 9.5 5.1 5.6 6.9 0.5 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 F-box-like PF12937.7 PRP86366.1 - 3.6e-07 30.0 0.8 1.4e-06 28.1 0.8 2.1 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 PRP86366.1 - 0.00018 21.8 14.5 6.1 7.4 1.5 6.0 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) F-box PF00646.33 PRP86366.1 - 0.015 15.1 0.5 0.064 13.2 0.5 2.1 1 0 0 1 1 1 0 F-box domain FNIP PF05725.12 PRP86366.1 - 0.049 13.8 8.8 1.9 8.7 0.1 5.1 5 3 0 5 5 5 0 FNIP Repeat LRR_6 PF13516.6 PRP86366.1 - 0.47 10.6 11.2 95 3.4 0.1 7.1 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 PRP86366.1 - 1.8 9.4 19.2 6 7.8 1.4 7.5 9 1 0 9 9 9 0 Leucine Rich Repeat DUF5465 PF17553.2 PRP86366.1 - 3.7 8.3 5.0 1.5 9.5 0.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5465) PP2C PF00481.21 PRP86367.1 - 5.6e-11 42.6 0.7 9.7e-06 25.4 0.1 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PRP86367.1 - 3.9e-10 40.0 0.0 6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Polysacc_deac_2 PF04748.13 PRP86367.1 - 0.0064 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase PP2C_2 PF13672.6 PRP86367.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C Barstar PF01337.18 PRP86367.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Barstar (barnase inhibitor) DUF1296 PF06972.11 PRP86367.1 - 0.11 12.7 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DivIVA PF05103.13 PRP86368.1 - 0.0086 16.2 4.4 0.0086 16.2 4.4 4.6 1 1 3 4 4 4 1 DivIVA protein DUF812 PF05667.11 PRP86368.1 - 9.9 4.9 70.9 1.1 8.1 19.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) EF-hand_4 PF12763.7 PRP86373.1 - 9.4e-29 99.4 0.0 1.7e-15 56.9 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 PRP86373.1 - 6.6e-09 34.7 2.6 0.035 13.6 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PRP86373.1 - 9.4e-08 32.4 2.2 4.9e-06 26.9 1.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP86373.1 - 0.00022 20.9 2.7 0.028 14.3 0.1 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 PRP86373.1 - 0.0061 16.4 2.9 1.5 8.8 0.4 3.6 2 1 0 3 3 3 1 EF-hand domain pair Pilosulin PF17499.2 PRP86373.1 - 0.072 13.3 1.4 0.15 12.3 0.4 2.1 2 0 0 2 2 2 0 Ant venom peptides DUF3584 PF12128.8 PRP86373.1 - 2.4 5.6 55.8 3.6 5.0 55.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DSPc PF00782.20 PRP86374.1 - 1.7e-05 24.6 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP86374.1 - 9.1e-05 22.1 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP86374.1 - 0.0024 17.9 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family RL PF17797.1 PRP86374.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 RL domain Nup35_RRM_2 PF14605.6 PRP86374.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif G-alpha PF00503.20 PRP86375.1 - 1.7e-107 359.6 12.3 3.5e-107 358.6 12.3 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PRP86375.1 - 5.9e-15 55.2 0.5 2.8e-12 46.4 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.6 PRP86375.1 - 0.0046 16.7 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 PRP86375.1 - 0.019 14.5 0.1 0.33 10.5 0.2 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 PRP86375.1 - 0.031 14.5 1.7 4.6 7.5 0.1 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PRP86375.1 - 0.065 13.3 0.3 2.9 8.0 0.0 2.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase SUR7 PF06687.12 PRP86376.1 - 7.4e-05 22.5 1.1 0.0025 17.5 0.9 2.4 1 1 0 2 2 2 1 SUR7/PalI family MARVEL PF01284.23 PRP86376.1 - 0.023 14.7 4.9 0.1 12.6 0.6 2.3 1 1 1 2 2 2 0 Membrane-associating domain Abhydrolase_1 PF00561.20 PRP86377.1 - 1.4e-33 116.6 0.0 1.9e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP86377.1 - 6.4e-05 23.7 0.1 8.9e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 PRP86377.1 - 0.00017 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 PRP86377.1 - 0.02 14.2 0.0 0.06 12.6 0.0 1.8 1 1 0 1 1 1 0 Serine aminopeptidase, S33 PTR2 PF00854.21 PRP86378.1 - 9.1e-92 307.9 6.3 1.5e-91 307.2 6.3 1.3 1 0 0 1 1 1 1 POT family Sugar_tr PF00083.24 PRP86378.1 - 0.0011 18.0 1.1 0.0011 18.0 1.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3087 PF11286.8 PRP86378.1 - 0.068 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF2542 PF10808.8 PRP86378.1 - 0.17 12.4 2.6 1.1 9.8 0.7 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2542) SelP_N PF04592.14 PRP86381.1 - 8.5 5.7 10.1 14 5.0 10.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region JmjC PF02373.22 PRP86382.1 - 6.9e-17 61.9 0.1 4e-16 59.5 0.1 2.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase CSRNP_N PF16019.5 PRP86382.1 - 5e-09 36.4 9.6 1.4e-07 31.7 10.5 6.0 4 2 2 6 6 6 2 Cysteine/serine-rich nuclear protein N-terminus Jas PF16135.5 PRP86382.1 - 1e-05 25.6 0.5 1e-05 25.6 0.5 4.4 4 0 0 4 4 4 1 TPL-binding domain in jasmonate signalling GATA PF00320.27 PRP86382.1 - 7.5e-05 22.3 7.9 7.5e-05 22.3 7.9 2.6 2 0 0 2 2 2 1 GATA zinc finger C1_2 PF03107.16 PRP86382.1 - 0.00057 20.1 2.7 0.00057 20.1 2.7 4.9 6 0 0 6 6 6 1 C1 domain Cupin_2 PF07883.11 PRP86382.1 - 0.022 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Snapin_Pallidin PF14712.6 PRP86382.1 - 5.6 7.5 24.2 0.24 11.8 14.0 3.0 2 0 0 2 2 2 0 Snapin/Pallidin CLU PF13236.6 PRP86383.1 - 2.3e-48 165.0 0.0 4.8e-48 163.9 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP86383.1 - 1.1e-08 35.4 0.0 3.8e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_17 PF13431.6 PRP86383.1 - 9.2e-06 25.7 1.8 0.12 12.8 0.8 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCHH PF10283.9 PRP86383.1 - 0.00029 20.8 4.2 0.00029 20.8 4.2 2.7 3 0 0 3 3 3 1 PBZ domain TPR_12 PF13424.6 PRP86383.1 - 0.0018 18.5 3.2 0.024 14.9 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP86383.1 - 0.0085 16.1 0.0 0.0085 16.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP86383.1 - 0.033 15.0 0.0 2 9.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP86383.1 - 0.035 13.9 9.2 0.089 12.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP86383.1 - 0.061 13.6 5.1 0.44 10.9 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP86383.1 - 0.061 13.4 1.3 6.6 7.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP86383.1 - 0.97 9.4 3.2 41 4.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NCKAP5 PF15246.6 PRP86384.1 - 1.3 8.5 49.7 0.046 13.3 36.6 2.6 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein Xpo1 PF08389.12 PRP86387.1 - 0.00015 21.8 6.9 0.033 14.3 0.0 4.0 4 1 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.19 PRP86387.1 - 0.00048 20.0 0.1 0.0029 17.5 0.1 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain CDC24_OB1 PF17246.2 PRP86387.1 - 0.0033 17.5 0.1 0.0096 16.0 0.1 1.8 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 SPT_ssu-like PF11779.8 PRP86388.1 - 2.6e-07 30.1 0.4 3.8e-07 29.6 0.4 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Tctex-1 PF03645.13 PRP86389.1 - 2.9e-29 101.3 0.0 3.6e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family SLATT_2 PF18183.1 PRP86389.1 - 0.12 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 2 F5_F8_type_C PF00754.25 PRP86390.1 - 2.8e-08 33.9 0.0 4.5e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 PRP86390.1 - 0.00017 21.6 0.1 0.00027 21.0 0.1 1.3 1 1 0 1 1 1 1 XRCC1 N terminal domain SNF2_N PF00176.23 PRP86391.1 - 1.1e-53 182.2 0.4 2.8e-53 180.9 0.4 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP86391.1 - 3.4e-18 66.0 0.0 4.3e-17 62.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP86391.1 - 2e-09 37.7 0.0 4.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PRP86391.1 - 2.3e-05 23.7 0.0 5.4e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 PRP86391.1 - 8.5e-05 22.3 0.0 0.00021 21.1 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2439 PF10382.9 PRP86391.1 - 0.00011 22.4 0.2 0.00062 20.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) ERCC3_RAD25_C PF16203.5 PRP86391.1 - 0.0019 17.5 0.0 0.012 14.9 0.0 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Hemerythrin PF01814.23 PRP86392.1 - 1.8e-10 41.5 6.2 3.6e-10 40.6 6.2 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain 4HB_MCP_1 PF12729.7 PRP86392.1 - 0.17 11.5 0.6 0.99 8.9 0.0 2.0 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction TPR_2 PF07719.17 PRP86394.1 - 3.3e-23 79.9 24.5 0.00059 19.8 0.1 10.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 PRP86394.1 - 1.3e-18 65.9 25.2 0.00051 19.8 0.0 9.2 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 PRP86394.1 - 2.8e-18 64.5 19.5 0.0022 18.1 0.0 11.0 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP86394.1 - 6.4e-17 60.6 13.2 0.0038 17.5 0.0 9.5 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP86394.1 - 4.7e-16 59.1 13.5 7.3e-05 23.3 0.0 7.2 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 PRP86394.1 - 4.2e-14 52.6 19.3 0.011 16.0 0.4 8.4 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP86394.1 - 3.5e-12 46.6 12.1 0.0092 16.5 0.0 6.6 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 PRP86394.1 - 4e-12 45.3 10.4 0.48 10.6 0.0 9.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP86394.1 - 5.4e-12 45.5 12.3 0.0027 18.4 0.3 9.1 8 1 2 10 10 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP86394.1 - 2.9e-09 37.0 12.8 0.0033 17.6 0.1 5.5 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PRP86394.1 - 1.9e-06 27.9 7.3 0.22 11.7 0.3 6.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 PRP86394.1 - 3.7e-05 24.1 19.3 2.7 8.8 0.1 9.0 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_3 PF07720.12 PRP86394.1 - 0.002 18.1 1.7 0.033 14.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP86394.1 - 0.0026 17.4 8.2 0.14 11.8 0.0 5.6 6 0 0 6 6 6 1 TPR repeat TPR_21 PF09976.9 PRP86394.1 - 0.0048 16.6 0.5 0.42 10.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat-like domain HR1 PF02185.16 PRP86394.1 - 0.086 13.0 0.1 0.26 11.4 0.1 1.8 1 0 0 1 1 1 0 Hr1 repeat TPR_10 PF13374.6 PRP86394.1 - 1.7 8.6 14.8 12 5.9 0.1 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat MIT PF04212.18 PRP86394.1 - 2.2 8.4 6.5 5 7.3 0.4 3.6 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Pkinase_Tyr PF07714.17 PRP86395.1 - 1e-67 228.2 0.0 1.3e-66 224.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86395.1 - 1.6e-48 165.4 0.0 7.7e-48 163.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP86395.1 - 4.2e-26 90.6 66.0 6.7e-05 23.2 0.2 13.0 9 2 4 13 13 13 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP86395.1 - 1.1e-25 89.2 61.4 2.4e-05 24.0 4.8 11.2 6 1 7 13 13 13 10 Leucine rich repeat LRR_6 PF13516.6 PRP86395.1 - 6.2e-11 41.4 42.9 0.82 9.9 0.0 15.3 16 0 0 16 16 16 4 Leucine Rich repeat LRR_1 PF00560.33 PRP86395.1 - 1.1e-08 34.5 47.6 7.3 7.6 0.1 17.3 19 3 0 19 19 17 2 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP86395.1 - 1.9e-05 23.7 0.0 3.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP86395.1 - 0.0032 16.5 0.3 0.012 14.5 0.3 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP86395.1 - 0.0056 16.0 0.0 0.047 13.0 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP86395.1 - 0.056 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like EphA2_TM PF14575.6 PRP86395.1 - 0.13 13.1 0.1 0.32 11.9 0.1 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CorA PF01544.18 PRP86396.1 - 5.2e-21 75.2 0.1 5.2e-21 75.2 0.1 2.9 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein TPR_MLP1_2 PF07926.12 PRP86396.1 - 0.013 15.5 25.8 0.37 10.8 8.7 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 PRP86396.1 - 0.013 13.7 14.1 0.032 12.4 13.6 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA RPW8 PF05659.11 PRP86396.1 - 0.058 13.1 10.1 0.032 13.9 1.5 2.9 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc7 PF08317.11 PRP86396.1 - 0.058 12.3 25.6 0.019 13.9 8.4 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 PRP86396.1 - 0.077 13.2 27.4 0.023 15.0 12.2 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Prominin PF05478.11 PRP86396.1 - 0.41 8.5 11.6 0.25 9.3 8.4 2.0 1 1 0 1 1 1 0 Prominin Golgin_A5 PF09787.9 PRP86396.1 - 0.48 9.8 26.2 0.11 11.9 17.0 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 TACC_C PF05010.14 PRP86396.1 - 1.4 8.7 21.2 12 5.7 19.0 2.6 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4795 PF16043.5 PRP86396.1 - 1.4 8.5 17.7 2.8 7.5 17.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Phage_GP20 PF06810.11 PRP86396.1 - 2.3 8.0 20.6 3.1 7.6 0.8 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 bZIP_1 PF00170.21 PRP86396.1 - 2.4 8.3 8.4 1.2 9.3 1.0 3.8 2 2 2 4 4 4 0 bZIP transcription factor TIM21 PF08294.11 PRP86396.1 - 2.7 7.8 5.0 0.35 10.8 0.2 1.9 2 0 0 2 2 1 0 TIM21 OmpH PF03938.14 PRP86396.1 - 2.8 8.3 18.0 2.6 8.4 5.1 2.8 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) FliJ PF02050.16 PRP86396.1 - 3.5 7.9 15.5 3.4 7.9 1.7 2.8 2 1 0 2 2 2 0 Flagellar FliJ protein BLOC1_2 PF10046.9 PRP86396.1 - 3.5 8.0 10.3 2.1 8.7 2.5 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 PRP86396.1 - 3.6 7.6 8.3 4.8 7.2 1.1 3.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-H PF05837.12 PRP86396.1 - 3.7 8.0 24.7 0.27 11.7 1.8 3.9 2 1 1 3 3 3 0 Centromere protein H (CENP-H) SHE3 PF17078.5 PRP86396.1 - 4.9 6.8 19.8 1.4 8.6 9.2 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF1664 PF07889.12 PRP86396.1 - 6.6 6.8 17.1 4.8 7.2 6.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 PRP86396.1 - 6.8 7.4 15.9 1.6 9.5 3.6 3.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) ZapD PF07072.11 PRP86396.1 - 7.7 6.2 11.3 1.2 8.9 4.0 2.5 2 0 0 2 2 2 0 Cell division protein FlaC_arch PF05377.11 PRP86396.1 - 8 6.9 13.0 0.3 11.5 1.8 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Tfb5 PF06331.12 PRP86397.1 - 1.4e-06 28.2 0.1 2.1e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 CdvA PF18822.1 PRP86397.1 - 0.027 14.3 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 CdvA-like coiled-coil domain LPD26 PF18842.1 PRP86397.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 26 LBP_BPI_CETP PF01273.25 PRP86398.1 - 0.058 13.0 0.2 0.49 10.0 0.2 2.1 1 1 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain JHBP PF06585.11 PRP86398.1 - 0.059 12.5 0.3 0.13 11.4 0.3 1.5 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) Hormone_3 PF00159.18 PRP86398.1 - 0.061 13.4 1.9 4 7.6 0.3 2.4 2 0 0 2 2 2 0 Pancreatic hormone peptide NUC PF18510.1 PRP86398.1 - 1 9.8 5.1 0.3 11.5 1.1 2.1 2 0 0 2 2 2 0 Nuclease domain CLU PF13236.6 PRP86399.1 - 8.1e-51 173.0 0.0 2.2e-50 171.6 0.0 1.8 2 0 0 2 2 2 1 Clustered mitochondria Protoglobin PF11563.8 PRP86399.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Protoglobin eIF3_p135 PF12807.7 PRP86399.1 - 0.022 14.8 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Suf PF05843.14 PRP86401.1 - 1.2e-50 173.2 18.6 1.4e-45 156.6 8.1 5.4 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 PRP86401.1 - 5.9e-11 42.2 7.8 0.00021 21.9 1.4 5.7 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP86401.1 - 3e-08 33.2 4.6 0.011 15.8 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP86401.1 - 3.2e-06 27.7 5.4 0.00015 22.4 0.9 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP86401.1 - 4.7e-05 23.3 9.6 0.083 13.1 0.2 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP86401.1 - 0.00014 22.3 3.4 0.00022 21.7 0.3 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat HAT PF02184.16 PRP86401.1 - 0.005 16.8 2.6 0.39 10.7 0.6 3.6 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat TPR_15 PF13429.6 PRP86401.1 - 0.0055 16.0 4.0 5.8 6.0 0.0 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP86401.1 - 0.011 15.9 1.7 0.075 13.3 0.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PRP86401.1 - 0.022 14.7 14.7 0.4 10.7 0.0 5.1 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 PRP86401.1 - 0.076 13.7 5.4 3.1 8.6 0.1 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP86401.1 - 1.9 8.5 6.4 44 4.1 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat CLU PF13236.6 PRP86402.1 - 7.1e-54 183.0 0.0 1.5e-53 181.9 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria DUF3759 PF12585.8 PRP86402.1 - 8.9e-34 115.4 7.0 2.2e-33 114.1 7.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) PH PF00169.29 PRP86402.1 - 3.5e-16 59.6 1.6 1.5e-15 57.6 0.0 2.9 3 0 0 3 3 3 1 PH domain Abhydro_lipase PF04083.16 PRP86402.1 - 3.2e-14 52.2 0.0 8.6e-14 50.9 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 PRP86402.1 - 1.3e-05 25.0 0.0 4.7e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold eIF3_p135 PF12807.7 PRP86402.1 - 0.0036 17.3 0.0 0.0036 17.3 0.0 2.8 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 PH_8 PF15409.6 PRP86402.1 - 0.01 16.1 0.1 0.037 14.3 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain DsrC PF04358.13 PRP86402.1 - 0.02 15.4 0.6 0.081 13.4 0.6 2.0 1 0 0 1 1 1 0 DsrC like protein PH_11 PF15413.6 PRP86402.1 - 0.048 14.1 0.0 0.048 14.1 0.0 3.1 4 0 0 4 4 4 0 Pleckstrin homology domain Pkinase PF00069.25 PRP86403.1 - 3.3e-42 144.7 0.0 5.1e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86403.1 - 3.4e-17 62.6 0.0 5.7e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase BAG PF02179.16 PRP86403.1 - 2e-16 60.2 1.3 3.7e-16 59.3 1.3 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 PRP86403.1 - 1.8e-05 24.4 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family APH PF01636.23 PRP86403.1 - 0.00013 21.9 0.3 0.28 11.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP86403.1 - 0.00014 21.3 0.3 0.00024 20.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP86403.1 - 0.052 13.1 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 PRP86403.1 - 0.093 12.0 0.0 0.2 10.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Glyco_hydro_125 PF06824.11 PRP86404.1 - 9.3e-05 21.5 0.0 0.00013 21.0 0.0 1.2 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) PPP4R2 PF09184.11 PRP86405.1 - 8.5e-17 61.7 0.1 1.3e-16 61.1 0.1 1.3 1 0 0 1 1 1 1 PPP4R2 TEA PF01285.18 PRP86406.1 - 0.015 15.4 2.8 2.4 8.3 0.3 2.9 3 0 0 3 3 3 0 TEA/ATTS domain GpcrRhopsn4 PF10192.9 PRP86407.1 - 3e-06 26.8 10.0 3e-06 26.8 10.0 2.3 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 PRP86407.1 - 0.35 10.1 26.3 4.2 6.5 26.3 2.1 1 1 0 1 1 1 0 Lung seven transmembrane receptor DUF1180 PF06679.12 PRP86408.1 - 0.13 12.6 0.3 0.24 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PPR_2 PF13041.6 PRP86410.1 - 6.8e-16 58.2 0.8 8.2e-06 25.9 0.0 5.9 6 0 0 6 6 6 4 PPR repeat family PPR_3 PF13812.6 PRP86410.1 - 2.5e-07 30.7 3.2 0.21 11.7 0.1 4.7 1 1 4 5 5 5 4 Pentatricopeptide repeat domain ATP-grasp PF02222.22 PRP86410.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain PPR_1 PF12854.7 PRP86410.1 - 0.035 13.8 0.3 6.2 6.6 0.0 4.0 4 0 0 4 4 4 0 PPR repeat LytTR PF04397.15 PRP86410.1 - 0.052 13.8 0.2 7.3 6.9 0.0 2.5 2 0 0 2 2 2 0 LytTr DNA-binding domain PPR PF01535.20 PRP86410.1 - 0.29 11.5 14.7 11 6.5 0.0 6.7 7 1 0 7 7 7 0 PPR repeat WD40 PF00400.32 PRP86411.1 - 5.3e-12 46.1 7.9 0.0072 17.2 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP86411.1 - 2.8e-08 33.9 0.1 5.2 7.5 0.0 6.4 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PRP86411.1 - 0.031 13.9 0.0 2.2 7.8 0.0 3.3 2 1 1 3 3 3 0 PQQ-like domain Pkinase_Tyr PF07714.17 PRP86412.1 - 3.6e-81 272.3 0.0 6e-81 271.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86412.1 - 2.6e-50 171.3 0.0 4.4e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP86412.1 - 1e-34 118.1 108.5 4.7e-06 26.3 2.7 16.2 10 3 9 20 20 20 16 Leucine rich repeat LRR_4 PF12799.7 PRP86412.1 - 4.6e-33 112.7 121.0 3.8e-07 30.3 0.8 20.1 11 5 9 22 22 22 17 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP86412.1 - 1e-07 31.4 87.0 1.3 9.2 0.0 24.0 28 0 0 28 28 28 3 Leucine Rich repeat LRR_1 PF00560.33 PRP86412.1 - 2.2e-05 24.4 99.5 6.3 7.8 0.2 26.7 29 5 0 29 29 29 4 Leucine Rich Repeat Kinase-like PF14531.6 PRP86412.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like LRR_9 PF14580.6 PRP86412.1 - 4.3 6.8 18.0 0.09 12.3 2.2 4.5 5 1 0 5 5 5 0 Leucine-rich repeat Colipase-like PF15083.6 PRP86413.1 - 0.023 14.8 12.4 0.05 13.7 12.4 1.5 1 0 0 1 1 1 0 Colipase-like Myosin_head PF00063.21 PRP86414.1 - 4.9e-257 854.6 3.8 7e-257 854.0 3.8 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 PRP86414.1 - 4e-31 108.1 6.1 5.7e-31 107.6 5.1 1.8 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding Acetyltransf_CG PF14542.6 PRP86414.1 - 1.7e-18 66.5 0.0 4.4e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase SH3_2 PF07653.17 PRP86414.1 - 3.8e-13 48.9 0.1 1.9e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 PRP86414.1 - 1.5e-11 43.7 0.0 3.5e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP86414.1 - 5e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Hpr_kinase_C PF07475.12 PRP86414.1 - 0.0012 18.4 1.1 0.86 9.1 0.0 2.7 3 0 0 3 3 3 2 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 PRP86414.1 - 0.0046 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.7 PRP86414.1 - 0.03 13.2 0.2 0.2 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.6 PRP86414.1 - 0.059 13.6 0.3 0.28 11.4 0.3 2.2 1 1 0 1 1 1 0 AAA domain bPH_2 PF03703.14 PRP86414.1 - 0.072 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial PH domain ABC_tran PF00005.27 PRP86414.1 - 0.11 13.0 0.2 0.47 11.0 0.0 2.1 2 0 0 2 2 2 0 ABC transporter DUF3482 PF11981.8 PRP86415.1 - 0.52 9.7 7.6 0.11 11.9 3.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) Dsh_C PF12316.8 PRP86415.1 - 1.9 8.9 8.6 2.4 8.5 8.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DDHD PF02862.17 PRP86415.1 - 2.7 8.1 8.3 2.9 8.0 8.3 1.1 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 PRP86415.1 - 3.5 7.3 13.7 4 7.1 13.7 1.1 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 PRP86416.1 - 7.7e-37 127.1 0.3 2.7e-36 125.3 0.3 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86416.1 - 4.2e-32 111.4 0.8 1.1e-31 110.0 0.8 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 PRP86416.1 - 1.9e-21 76.4 5.4 1e-09 38.8 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP86416.1 - 9.6e-13 48.4 1.0 0.0001 22.8 0.1 4.2 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP86416.1 - 2.6e-12 46.7 0.4 0.00018 21.7 0.2 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP86416.1 - 6e-11 42.3 0.0 1.6e-05 25.1 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP86416.1 - 6.5e-10 38.4 0.0 0.05 14.2 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat FERM_f0 PF16511.5 PRP86416.1 - 0.0025 18.1 0.1 0.0086 16.4 0.1 2.0 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM CENP-H PF05837.12 PRP86416.1 - 0.75 10.2 6.6 3 8.3 0.5 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Mto2_bdg PF12808.7 PRP86416.1 - 1.8 9.0 11.5 0.8 10.0 1.3 3.3 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CDP-OH_P_transf PF01066.21 PRP86417.1 - 2e-08 34.9 0.3 2e-08 34.9 0.3 3.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Zn_clus PF00172.18 PRP86418.1 - 1.6e-07 31.3 9.5 2.7e-07 30.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 PRP86418.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 PAS fold Pkinase PF00069.25 PRP86420.1 - 4.7e-54 183.5 0.0 5.6e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86420.1 - 6.7e-27 94.4 0.0 8.5e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP86420.1 - 0.0071 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP86420.1 - 0.011 15.7 0.0 0.071 13.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myotub-related PF06602.14 PRP86422.1 - 4.5e-135 450.1 0.0 6.9e-135 449.5 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PH PF00169.29 PRP86422.1 - 7.2e-25 87.5 3.4 8.3e-19 68.0 0.2 2.8 2 0 0 2 2 2 2 PH domain PH_3 PF14593.6 PRP86422.1 - 1e-09 38.4 1.2 4e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 PRP86422.1 - 0.0005 20.3 0.1 0.0017 18.6 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 PRP86422.1 - 0.0013 19.1 0.3 0.72 10.2 0.0 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain Y_phosphatase3 PF13350.6 PRP86422.1 - 0.0014 18.7 0.0 0.0039 17.2 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family PH_11 PF15413.6 PRP86422.1 - 0.0015 18.9 11.4 0.92 10.0 0.9 4.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_6 PF15406.6 PRP86422.1 - 0.0025 18.1 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain Y_phosphatase PF00102.27 PRP86422.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PH_13 PF16652.5 PRP86422.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Peptidase_M76 PF09768.9 PRP86423.1 - 3.2e-53 180.0 5.8 3.7e-53 179.8 5.8 1.0 1 0 0 1 1 1 1 Peptidase M76 family LELP1 PF15042.6 PRP86423.1 - 0.097 13.1 0.2 0.097 13.1 0.2 1.8 2 1 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Ferric_reduct PF01794.19 PRP86424.1 - 1.2e-08 35.1 12.9 3.6e-08 33.6 12.9 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 PRP86424.1 - 6.6e-06 26.3 0.1 0.003 17.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PRP86424.1 - 9.7e-06 25.6 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Cbl_N3 PF02762.14 PRP86424.1 - 0.053 13.4 0.0 0.85 9.5 0.0 2.5 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain Tautomerase_3 PF14832.6 PRP86425.1 - 2.7e-11 43.9 0.0 3.1e-11 43.6 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase_2 PF14552.6 PRP86425.1 - 0.021 14.9 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme Pkinase PF00069.25 PRP86426.1 - 2.4e-56 191.0 0.0 4.3e-56 190.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86426.1 - 2.1e-36 125.6 0.0 3.9e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PRP86426.1 - 6.3e-09 34.8 0.3 0.00031 20.1 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PRP86426.1 - 1.2e-08 35.3 0.2 1.3e-07 32.0 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP86426.1 - 6.6e-07 28.8 0.7 0.034 14.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PRP86426.1 - 1.9e-05 24.0 1.1 0.036 13.6 0.1 2.8 2 0 0 2 2 2 2 EF hand Haspin_kinase PF12330.8 PRP86426.1 - 8.1e-05 21.7 0.1 0.00019 20.5 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP86426.1 - 0.00088 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_8 PF13833.6 PRP86426.1 - 0.0026 17.6 0.1 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP86426.1 - 0.012 15.9 0.0 0.13 12.6 0.0 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_Tyr PF07714.17 PRP86427.1 - 1.2e-63 214.9 0.0 2.3e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86427.1 - 3.1e-47 161.2 0.0 5.6e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LIM PF00412.22 PRP86427.1 - 1.6e-17 63.5 19.5 6.6e-09 35.9 4.3 2.6 2 0 0 2 2 2 2 LIM domain Kdo PF06293.14 PRP86427.1 - 0.00024 20.5 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP86427.1 - 0.013 15.5 0.0 2.7 7.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP86427.1 - 0.046 12.5 0.0 0.083 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 PRP86427.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family E1-E2_ATPase PF00122.20 PRP86428.1 - 1.6e-36 125.5 0.0 1.6e-36 125.5 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PRP86428.1 - 2e-13 51.1 0.0 5.4e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 PRP86428.1 - 3.5e-10 40.1 0.1 3.5e-10 40.1 0.1 2.7 2 1 1 3 3 3 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 PRP86428.1 - 7.4e-06 25.6 0.0 3.2e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PRP86428.1 - 0.00031 20.8 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) MORN PF02493.20 PRP86429.1 - 1.4e-21 75.0 24.5 1e-05 25.1 0.1 5.5 5 0 0 5 5 5 5 MORN repeat RICTOR_M PF14666.6 PRP86429.1 - 0.013 15.3 0.4 5.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain zf-RING-like PF08746.11 PRP86429.1 - 0.11 12.9 9.2 2 8.8 1.1 2.3 2 0 0 2 2 2 0 RING-like domain ZZ PF00569.17 PRP86430.1 - 9.1e-12 44.6 6.0 1.7e-11 43.7 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 PRP86430.1 - 1.3e-09 38.3 0.1 1.3e-09 38.3 0.1 2.9 4 1 0 4 4 4 1 SWIRM domain Myb_DNA-binding PF00249.31 PRP86430.1 - 2.8e-09 37.0 1.6 2.2e-08 34.2 0.0 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP86430.1 - 0.026 14.7 0.1 0.23 11.8 0.0 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain C1_2 PF03107.16 PRP86430.1 - 0.029 14.7 5.3 0.062 13.6 5.3 1.5 1 0 0 1 1 1 0 C1 domain zf-P11 PF03854.14 PRP86430.1 - 6.7 6.5 7.3 8 6.2 0.1 2.5 2 0 0 2 2 2 0 P-11 zinc finger Orthopox_B11R PF07033.11 PRP86430.1 - 8 6.3 6.5 2.2 8.1 1.4 2.3 2 0 0 2 2 2 0 Orthopoxvirus B11R protein EF-hand_13 PF17958.1 PRP86431.1 - 1.5e-17 63.1 0.1 4.1e-17 61.8 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 PRP86431.1 - 6.5e-15 55.3 6.8 3.5e-14 53.0 2.5 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP86431.1 - 9.8e-05 21.6 1.8 0.0031 17.0 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 PRP86431.1 - 0.00011 21.6 0.1 0.00038 19.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PRP86431.1 - 0.00014 21.5 4.3 0.0012 18.6 0.1 3.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 PRP86431.1 - 0.014 15.3 1.9 0.021 14.7 0.1 2.4 3 0 0 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP86431.1 - 0.71 10.2 6.4 2.7 8.3 0.2 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_Tyr PF07714.17 PRP86433.1 - 2.8e-22 79.3 0.0 6.8e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86433.1 - 8.3e-18 64.7 0.0 2.2e-17 63.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP86433.1 - 1.6e-06 28.6 5.9 1.6e-06 28.6 5.9 2.5 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif TIG PF01833.24 PRP86433.1 - 0.00077 19.5 3.3 0.0025 17.9 3.3 1.9 1 0 0 1 1 1 1 IPT/TIG domain Podoplanin PF05808.11 PRP86433.1 - 0.00091 19.4 0.6 0.00091 19.4 0.6 2.5 3 0 0 3 3 3 1 Podoplanin Syndecan PF01034.20 PRP86433.1 - 0.0023 17.8 0.7 0.0061 16.5 0.7 1.6 1 0 0 1 1 1 1 Syndecan domain Adeno_E3_CR2 PF02439.15 PRP86433.1 - 0.3 10.9 4.2 0.78 9.5 4.2 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 COMM_domain PF07258.14 PRP86434.1 - 7.9e-14 51.5 0.0 1.3e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 COMM domain VASt PF16016.5 PRP86435.1 - 4.9e-33 114.7 0.3 2.5e-31 109.2 0.1 2.4 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 PRP86435.1 - 2.8e-17 62.6 0.1 7.2e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 GRAM domain C2 PF00168.30 PRP86435.1 - 2.5e-07 30.9 0.0 6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain ChpXY PF10216.9 PRP86435.1 - 0.087 12.0 0.1 0.22 10.6 0.1 1.6 2 0 0 2 2 2 0 CO2 hydration protein (ChpXY) LRR_8 PF13855.6 PRP86436.1 - 2.6e-19 68.7 54.7 0.00023 20.9 0.4 9.2 7 2 3 11 11 11 8 Leucine rich repeat LRR_4 PF12799.7 PRP86436.1 - 1.2e-14 54.2 71.9 5.9e-05 23.4 4.8 11.5 6 3 3 10 10 10 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP86436.1 - 0.053 14.1 49.5 3.4 8.6 0.1 13.4 13 2 0 13 13 13 0 Leucine Rich Repeat Chlam_PMP PF02415.17 PRP86436.1 - 0.063 13.8 0.4 0.063 13.8 0.4 10.7 11 1 0 11 11 11 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat LRR_9 PF14580.6 PRP86436.1 - 0.96 8.9 5.0 18 4.8 0.0 3.4 2 1 0 3 3 3 0 Leucine-rich repeat Skp1_POZ PF03931.15 PRP86438.1 - 1.9e-11 44.0 0.0 6.1e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 PRP86438.1 - 0.012 15.8 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Big_2 PF02368.18 PRP86439.1 - 1.5e-24 85.7 25.0 5e-09 35.9 0.1 8.4 8 1 1 9 9 9 6 Bacterial Ig-like domain (group 2) Beta_helix PF13229.6 PRP86440.1 - 1.3e-08 34.8 26.4 0.00047 20.0 5.7 4.0 2 1 2 4 4 4 3 Right handed beta helix region UCH PF00443.29 PRP86442.1 - 7.8e-47 159.9 0.2 1.2e-45 156.1 0.2 2.7 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP86442.1 - 2e-26 93.3 1.1 4e-19 69.4 0.1 2.7 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 PRP86442.1 - 2.3e-06 27.2 4.1 5.3 6.9 0.0 5.4 5 0 0 5 5 5 3 Ubiquitin family USP7_C2 PF14533.6 PRP86442.1 - 4.3e-05 23.3 7.0 0.0087 15.8 2.4 3.4 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal Vfa1 PF08432.10 PRP86442.1 - 2.3 8.5 13.9 0.28 11.5 2.8 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 PRP86442.1 - 2.3 8.1 15.4 0.59 10.0 5.8 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PRKCSH PF07915.13 PRP86442.1 - 2.6 9.1 4.4 20 6.3 0.7 3.3 3 0 0 3 3 3 0 Glucosidase II beta subunit-like protein Nexin_C PF08628.12 PRP86442.1 - 2.9 8.5 6.6 0.45 11.1 0.5 2.8 3 0 0 3 3 3 0 Sorting nexin C terminal ORC_WH_C PF18137.1 PRP86442.1 - 4.4 7.4 7.7 0.47 10.5 0.9 2.5 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Oleosin PF01277.17 PRP86443.1 - 0.012 15.4 0.5 0.016 15.0 0.5 1.2 1 0 0 1 1 1 0 Oleosin YwiC PF14256.6 PRP86443.1 - 0.024 15.0 0.2 0.029 14.7 0.2 1.1 1 0 0 1 1 1 0 YwiC-like protein TPH PF13868.6 PRP86444.1 - 6.1e-52 176.3 150.0 6.1e-52 176.3 150.0 2.2 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain PH PF00169.29 PRP86445.1 - 2.9e-21 76.0 0.2 4e-21 75.5 0.2 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP86445.1 - 6.6e-08 32.9 3.1 1.7e-07 31.6 3.1 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PRP86445.1 - 0.0016 18.8 0.1 0.0075 16.6 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 PRP86445.1 - 0.0018 18.5 0.7 0.046 14.0 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 PRP86445.1 - 0.078 12.8 0.2 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Yae1_N PF09811.9 PRP86446.1 - 0.019 14.6 2.3 0.47 10.2 0.3 2.3 2 0 0 2 2 2 0 Essential protein Yae1, N terminal FHA PF00498.26 PRP86448.1 - 0.019 15.3 0.0 0.47 10.8 0.0 2.4 2 0 0 2 2 2 0 FHA domain Yop-YscD_cpl PF16697.5 PRP86448.1 - 0.059 13.7 0.2 0.26 11.6 0.0 2.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain ZapB PF06005.12 PRP86448.1 - 8.8 6.9 15.6 16 6.1 12.4 2.7 2 1 0 2 2 2 0 Cell division protein ZapB MFS_1 PF07690.16 PRP86449.1 - 1.1e-26 93.7 21.8 2.6e-18 66.1 4.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 PRP86449.1 - 9.2e-07 28.6 8.3 9.2e-07 28.6 8.3 2.7 2 1 0 2 2 2 1 Nodulin-like TetR_C_23 PF17931.1 PRP86449.1 - 0.091 12.9 0.5 0.22 11.7 0.5 1.7 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RhoGEF PF00621.20 PRP86450.1 - 8.7e-35 120.6 0.2 1.3e-34 120.0 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 PRP86450.1 - 8.5e-07 29.5 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 PRP86450.1 - 0.00022 21.1 0.2 0.72 9.6 0.0 2.5 1 1 1 2 2 2 2 Pleckstrin homology domain FG-GAP PF01839.23 PRP86451.1 - 1.8e-32 111.1 55.7 3.2e-07 30.3 3.8 7.7 6 1 1 7 7 7 7 FG-GAP repeat VCBS PF13517.6 PRP86451.1 - 1.2e-21 77.1 54.0 1.4e-07 32.0 3.5 5.9 2 2 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 PRP86451.1 - 1.2e-07 31.3 15.8 0.62 9.4 0.1 5.5 4 1 1 5 5 5 5 Insecticide toxin TcdB middle/N-terminal region Itfg2 PF15907.5 PRP86451.1 - 0.067 12.2 0.5 2.7 6.9 0.3 2.5 1 1 1 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 PulG PF11773.8 PRP86452.1 - 0.13 12.1 0.2 27 4.7 0.1 2.7 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin Claudin_2 PF13903.6 PRP86452.1 - 0.27 11.0 2.3 2.8 7.7 0.3 2.8 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction VKOR PF07884.14 PRP86452.1 - 8.6 6.6 9.9 0.53 10.5 0.4 3.1 2 1 1 3 3 3 0 Vitamin K epoxide reductase family A_deaminase PF00962.22 PRP86453.1 - 5.8e-174 578.0 0.0 2.7e-94 316.2 0.0 2.9 2 1 0 2 2 2 2 Adenosine/AMP deaminase CsoSCA PF08936.10 PRP86453.1 - 0.019 13.6 0.0 0.036 12.7 0.0 1.3 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase UNC-79 PF14776.6 PRP86453.1 - 1.1 8.0 5.4 1.8 7.3 5.4 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 PolC_DP2 PF03833.13 PRP86453.1 - 2.1 6.1 4.7 3.6 5.3 4.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 PRP86453.1 - 3.1 7.9 7.2 7.5 6.7 7.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon COX6A PF02046.15 PRP86454.1 - 2.4e-06 28.0 0.1 6.9e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa MORN PF02493.20 PRP86455.1 - 3.3e-60 196.5 69.4 1.1e-06 28.2 3.0 13.7 13 0 0 13 13 13 12 MORN repeat RabGAP-TBC PF00566.18 PRP86455.1 - 1.3e-52 178.6 1.9 2e-52 178.0 1.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3048_C PF17479.2 PRP86455.1 - 0.099 13.0 28.3 5.4 7.4 0.1 6.8 2 2 5 7 7 7 0 Protein of unknown function (DUF3048) C-terminal domain PNP_UDP_1 PF01048.20 PRP86457.1 - 3.7e-56 190.0 5.2 9.9e-36 123.1 0.6 3.3 3 0 0 3 3 3 3 Phosphorylase superfamily His_Phos_2 PF00328.22 PRP86457.1 - 3.5e-26 92.4 0.0 4.9e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Ank_2 PF12796.7 PRP86458.1 - 2.1e-09 37.8 0.2 0.0095 16.5 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP86458.1 - 9.9e-05 22.5 1.2 13 6.8 0.0 5.9 7 0 0 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 PRP86458.1 - 0.00014 22.4 1.8 1.7 9.3 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP86458.1 - 0.0012 19.1 0.1 9.7 6.6 0.0 4.5 2 2 3 5 5 5 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP86460.1 - 2.8e-07 31.0 1.2 0.27 11.8 0.0 4.9 4 2 1 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP86460.1 - 0.00056 19.7 1.0 0.0014 18.5 1.0 1.7 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 PRP86460.1 - 0.001 19.6 0.0 0.051 14.2 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) F-box PF00646.33 PRP86460.1 - 0.0015 18.4 2.9 0.0041 17.0 2.9 1.8 1 0 0 1 1 1 1 F-box domain Ank_5 PF13857.6 PRP86460.1 - 0.068 13.5 0.2 20 5.6 0.0 4.0 4 1 1 5 5 5 0 Ankyrin repeats (many copies) F-box_4 PF15966.5 PRP86460.1 - 0.083 12.8 0.5 0.2 11.6 0.5 1.6 1 0 0 1 1 1 0 F-box NmrA PF05368.13 PRP86461.1 - 5.9e-20 71.8 0.0 8.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP86461.1 - 0.037 13.9 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Alginate_lyase PF05426.12 PRP86462.1 - 1.3e-13 51.1 5.6 2.4e-13 50.2 5.6 1.4 1 0 0 1 1 1 1 Alginate lyase adh_short PF00106.25 PRP86463.1 - 2e-26 92.6 0.2 3e-26 92.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP86463.1 - 1.4e-22 80.4 0.1 1.9e-22 80.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP86463.1 - 1.8e-08 34.5 0.1 2.6e-08 34.0 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP86463.1 - 0.00094 18.7 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP86463.1 - 0.0051 16.7 0.1 0.0075 16.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF5448 PF17526.2 PRP86463.1 - 0.016 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5448) RNase_P_pop3 PF08228.11 PRP86463.1 - 0.032 14.3 0.1 9.2 6.3 0.0 2.2 1 1 1 2 2 2 0 RNase P subunit Pop3 TPR_8 PF13181.6 PRP86464.1 - 0.13 12.6 0.6 0.39 11.0 0.6 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat P2X_receptor PF00864.19 PRP86465.1 - 5.2e-70 236.4 0.0 1.2e-69 235.2 0.0 1.5 1 1 0 1 1 1 1 ATP P2X receptor DUF5387 PF17361.2 PRP86465.1 - 0.11 12.2 0.3 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5387) NmrA PF05368.13 PRP86466.1 - 1.6e-47 162.1 0.0 2.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP86466.1 - 8.4e-14 51.9 0.0 2.3e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PRP86466.1 - 3.2e-05 23.1 0.0 5.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PRP86466.1 - 0.0001 21.8 0.0 0.00025 20.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 PRP86466.1 - 0.00029 21.2 0.1 0.00063 20.2 0.1 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 PRP86466.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 PRP86466.1 - 0.044 13.9 0.1 0.094 12.8 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 PRP86466.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain zf-AN1 PF01428.16 PRP86467.1 - 2.2e-21 75.7 34.2 3.5e-11 43.1 13.4 3.4 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 PRP86467.1 - 0.00065 20.0 26.0 0.048 14.0 5.6 3.3 2 1 1 3 3 3 3 Tc5 transposase C-terminal domain WD40 PF00400.32 PRP86468.1 - 7.2e-35 118.4 39.6 0.0019 19.0 0.2 12.9 13 0 0 13 13 13 11 WD domain, G-beta repeat Pkinase PF00069.25 PRP86469.1 - 2.1e-67 227.3 0.0 4.5e-67 226.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Y_phosphatase PF00102.27 PRP86469.1 - 3.1e-67 226.6 2.1 5.1e-33 114.6 0.0 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Pkinase_Tyr PF07714.17 PRP86469.1 - 2.9e-34 118.5 0.0 6.4e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Y_phosphatase3 PF13350.6 PRP86469.1 - 4.5e-05 23.5 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Pkinase_fungal PF17667.1 PRP86469.1 - 5.6e-05 22.1 0.1 0.0002 20.2 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP86469.1 - 7.6e-05 22.2 0.0 0.00019 20.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP86469.1 - 0.0019 17.6 0.2 0.0038 16.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DSPc PF00782.20 PRP86469.1 - 0.0021 17.9 0.1 0.0078 16.0 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Ank_2 PF12796.7 PRP86469.1 - 0.0025 18.4 0.0 0.031 14.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PTPlike_phytase PF14566.6 PRP86469.1 - 0.019 15.1 0.2 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate Ank_5 PF13857.6 PRP86469.1 - 0.025 14.9 2.9 0.47 10.8 0.1 3.7 3 1 1 4 4 4 0 Ankyrin repeats (many copies) FTA2 PF13095.6 PRP86469.1 - 0.12 12.0 0.2 0.79 9.3 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rubis-subs-bind PF09273.11 PRP86470.1 - 1.4e-15 58.1 2.9 1.4e-15 58.1 2.9 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 PRP86470.1 - 6.8e-13 49.3 4.6 7.5e-13 49.2 0.0 2.7 3 0 0 3 3 3 1 SET domain Phage_RpbA PF10789.9 PRP86470.1 - 0.01 15.9 7.4 0.37 10.9 2.4 2.7 2 1 0 2 2 2 0 Phage RNA polymerase binding, RpbA DUF2813 PF11398.8 PRP86470.1 - 0.4 9.9 8.3 0.038 13.3 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Gly_transf_sug PF04488.15 PRP86471.1 - 8.4e-11 42.4 0.2 2.1e-10 41.1 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 PRP86471.1 - 0.53 9.5 1.7 0.94 8.7 0.0 2.1 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain Gtr1_RagA PF04670.12 PRP86472.1 - 4.7e-68 229.0 1.5 7.5e-68 228.3 1.5 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region HhH-GPD PF00730.25 PRP86472.1 - 5.1e-21 75.2 0.0 6.1e-20 71.7 0.0 2.6 2 1 1 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PRP86472.1 - 1.2e-06 28.1 0.1 4e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif Roc PF08477.13 PRP86472.1 - 0.00015 22.0 0.0 0.0004 20.6 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP86472.1 - 0.0011 18.5 0.0 0.0034 16.8 0.0 1.9 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 PRP86472.1 - 0.0031 17.0 0.0 0.0089 15.5 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 PRP86472.1 - 0.037 13.6 0.2 0.074 12.6 0.2 1.6 1 0 0 1 1 1 0 Ras family CENP-F_leu_zip PF10473.9 PRP86473.1 - 0.00014 21.9 70.5 0.0067 16.5 5.8 5.8 1 1 4 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 PRP86473.1 - 0.00092 17.7 24.8 0.00092 17.7 24.8 3.2 1 1 2 3 3 3 2 Mitotic checkpoint protein Fez1 PF06818.15 PRP86473.1 - 0.0024 18.4 9.8 0.0024 18.4 9.8 4.5 1 1 2 3 3 2 1 Fez1 DUF4201 PF13870.6 PRP86473.1 - 0.0095 15.7 4.3 0.0095 15.7 4.3 4.7 2 2 2 4 4 3 1 Domain of unknown function (DUF4201) DUF812 PF05667.11 PRP86473.1 - 0.01 14.7 62.5 0.083 11.8 26.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Fib_alpha PF08702.10 PRP86473.1 - 0.012 15.8 2.5 0.012 15.8 2.5 5.6 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 PRP86473.1 - 0.064 13.5 71.3 6.9 6.8 25.3 4.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.12 PRP86473.1 - 0.22 11.4 3.1 50 4.0 0.3 4.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat GAS PF13851.6 PRP86473.1 - 0.24 10.7 68.4 0.31 10.4 23.1 5.4 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 PRP86473.1 - 0.4 10.0 63.5 0.078 12.3 10.1 5.4 3 2 2 5 5 5 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 PRP86473.1 - 2.4 7.0 69.5 7.8 5.3 13.0 4.9 1 1 4 5 5 5 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 PRP86473.1 - 5.6 7.1 66.3 1.5 9.0 22.1 5.1 1 1 6 7 7 6 0 Tropomyosin like UPF0242 PF06785.11 PRP86473.1 - 7.7 6.6 69.8 0.048 13.8 9.4 4.5 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Kelch_4 PF13418.6 PRP86474.1 - 1.5e-30 105.0 6.3 3.2e-08 33.4 0.1 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 PRP86474.1 - 6.9e-28 96.0 0.5 1.3e-07 31.1 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 PRP86474.1 - 1.5e-24 85.8 4.2 3.8e-08 33.4 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 PRP86474.1 - 1e-20 73.2 1.7 4.7e-08 33.0 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 PRP86474.1 - 1.5e-17 62.8 2.3 1.6e-06 27.8 0.1 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 PRP86474.1 - 7.3e-15 54.6 1.3 6.8e-07 29.1 0.1 4.3 5 0 0 5 5 5 2 Kelch motif SlyX PF04102.12 PRP86474.1 - 0.02 15.5 2.5 0.43 11.2 0.7 2.5 2 0 0 2 2 2 0 SlyX DUF4763 PF15960.5 PRP86474.1 - 0.13 11.5 5.8 0.2 10.9 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Atg14 PF10186.9 PRP86474.1 - 0.31 10.1 11.0 0.54 9.3 11.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NEMO PF11577.8 PRP86474.1 - 0.73 9.9 11.2 0.81 9.8 7.6 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Noelin-1 PF12308.8 PRP86474.1 - 1.1 9.3 3.6 29 4.7 0.5 3.0 3 0 0 3 3 3 0 Neurogenesis glycoprotein Prefoldin_2 PF01920.20 PRP86474.1 - 1.4 8.9 10.3 7.1 6.6 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit CtIP_N PF10482.9 PRP86474.1 - 1.5 8.9 9.3 0.87 9.6 5.0 2.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF641 PF04859.12 PRP86474.1 - 1.7 9.0 9.7 9.7 6.5 4.1 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) INCENP_ARK-bind PF03941.15 PRP86475.1 - 3.1e-13 49.4 0.1 3.1e-13 49.4 0.1 2.9 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region HA PF03457.14 PRP86475.1 - 0.0025 18.1 0.1 0.0025 18.1 0.1 3.6 3 1 0 3 3 3 1 Helicase associated domain PAN_4 PF14295.6 PRP86477.1 - 1.2e-16 60.3 26.2 8.4e-12 44.8 4.6 3.5 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 PRP86477.1 - 7.4e-13 48.3 8.4 3.4e-07 30.1 1.5 3.1 3 0 0 3 3 3 2 PAN domain Thaumatin PF00314.17 PRP86477.1 - 3.6e-07 30.0 6.7 3.6e-07 30.0 6.7 4.1 2 2 0 3 3 3 1 Thaumatin family PAN_3 PF08277.12 PRP86477.1 - 0.00064 19.5 11.0 0.18 11.7 3.0 3.1 2 0 0 2 2 2 2 PAN-like domain PAN_2 PF08276.11 PRP86477.1 - 0.001 19.2 20.8 0.0051 16.9 2.4 3.3 4 0 0 4 4 4 2 PAN-like domain MANEC PF07502.14 PRP86477.1 - 0.0019 18.4 9.1 0.15 12.3 1.9 2.8 2 0 0 2 2 2 2 MANEC domain Carb_bind PF10645.9 PRP86477.1 - 0.015 15.5 4.3 0.015 15.5 4.3 4.3 3 1 1 4 4 4 0 Carbohydrate binding DUF3746 PF12562.8 PRP86477.1 - 0.19 11.7 1.0 0.55 10.2 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) DUF842 PF05811.13 PRP86477.1 - 7 6.4 13.2 1.8 8.3 2.3 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) AA_permease PF00324.21 PRP86478.1 - 2.6e-121 405.5 41.9 2.6e-121 405.5 41.9 2.8 3 0 0 3 3 3 1 Amino acid permease Peptidase_C1 PF00112.23 PRP86478.1 - 6.4e-47 160.4 7.4 1e-46 159.8 7.4 1.3 1 0 0 1 1 1 1 Papain family cysteine protease AA_permease_2 PF13520.6 PRP86478.1 - 3.2e-35 121.8 45.5 3.2e-35 121.8 45.5 2.5 2 1 0 2 2 2 1 Amino acid permease Bac_rhodopsin PF01036.18 PRP86478.1 - 2.8e-32 112.1 13.0 2.8e-32 112.1 13.0 2.1 2 0 0 2 2 2 1 Bacteriorhodopsin-like protein PAN_4 PF14295.6 PRP86478.1 - 1.2e-09 38.0 2.9 3.4e-09 36.5 2.9 1.9 1 0 0 1 1 1 1 PAN domain Inhibitor_I29 PF08246.12 PRP86478.1 - 1.5e-08 34.9 2.6 1.5e-08 34.9 2.6 1.9 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP86478.1 - 3e-06 26.3 0.8 0.00024 20.0 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family PAN_1 PF00024.26 PRP86478.1 - 3.8e-06 26.8 0.4 9.4e-06 25.5 0.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP86478.1 - 1.1e-05 25.4 0.4 1.1e-05 25.4 0.4 2.0 2 0 0 2 2 2 1 PAN-like domain BrnA_antitoxin PF14384.6 PRP86478.1 - 0.14 12.6 0.0 0.29 11.7 0.0 1.5 1 0 0 1 1 1 0 BrnA antitoxin of type II toxin-antitoxin system Pro-kuma_activ PF09286.11 PRP86479.1 - 5.9e-31 107.7 0.0 1.1e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP86479.1 - 1.8e-08 34.0 0.1 3.2e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 Subtilase family SH2 PF00017.24 PRP86480.1 - 2e-14 53.4 0.0 7.8e-14 51.5 0.0 2.0 1 1 1 2 2 2 1 SH2 domain SH2_2 PF14633.6 PRP86480.1 - 0.029 13.8 0.1 0.11 11.9 0.0 1.8 1 1 1 2 2 2 0 SH2 domain DUF3006 PF11213.8 PRP86480.1 - 0.078 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Cob_adeno_trans PF01923.18 PRP86482.1 - 9.7e-48 162.4 0.0 1.9e-47 161.4 0.0 1.5 1 0 0 1 1 1 1 Cobalamin adenosyltransferase zf-4CXXC_R1 PF10497.9 PRP86482.1 - 1.5e-31 108.5 7.0 3.6e-31 107.3 7.0 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Chromo PF00385.24 PRP86482.1 - 1.7e-09 37.4 0.3 4.2e-09 36.2 0.3 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol_alpha_N PF12254.8 PRP86482.1 - 0.3 11.2 7.9 0.25 11.5 4.2 2.7 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal Pectate_lyase_3 PF12708.7 PRP86483.1 - 3.1e-07 30.5 7.7 3.1e-07 30.5 7.7 4.3 3 1 0 4 4 4 1 Pectate lyase superfamily protein CBM_35 PF16990.5 PRP86483.1 - 0.00018 21.8 1.1 0.00099 19.4 0.1 2.6 2 0 0 2 2 2 1 Carbohydrate binding module (family 35) CusF_Ec PF11604.8 PRP86483.1 - 0.027 14.4 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Copper binding periplasmic protein CusF DUF3244 PF11589.8 PRP86483.1 - 0.095 12.8 0.3 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) Ank_3 PF13606.6 PRP86484.1 - 3.7e-07 29.9 0.3 2.8 8.8 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_2 PF12796.7 PRP86484.1 - 1.6e-06 28.6 0.0 0.002 18.7 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP86484.1 - 1.4e-05 25.3 0.2 0.1 13.0 0.1 4.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP86484.1 - 0.041 14.5 0.1 2.3 8.9 0.0 3.7 3 1 0 3 3 3 0 Ankyrin repeats (many copies) UFD1 PF03152.14 PRP86485.1 - 1.5e-56 190.6 0.0 1.9e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Apt1 PF10351.9 PRP86485.1 - 4 6.2 6.2 5.1 5.8 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain EB1 PF03271.17 PRP86486.1 - 0.00048 20.3 0.7 0.00069 19.8 0.2 1.5 1 1 0 1 1 1 1 EB1-like C-terminal motif Pkinase PF00069.25 PRP86487.1 - 1.7e-44 152.2 0.0 2.3e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86487.1 - 7.7e-25 87.6 0.0 1.8e-24 86.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PRP86487.1 - 8.8e-10 38.5 0.0 1.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PRP86487.1 - 1.3e-06 27.9 0.0 3.5e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP86487.1 - 4.7e-06 26.7 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP86487.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP86487.1 - 0.0025 16.8 0.1 0.006 15.6 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain RasGEF PF00617.19 PRP86488.1 - 6e-54 182.9 0.2 6e-54 182.9 0.2 2.8 3 1 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 PRP86488.1 - 3.2e-11 43.4 0.9 1.1e-10 41.6 0.2 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif Pkinase PF00069.25 PRP86490.1 - 4e-47 160.8 0.1 6.9e-47 160.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 PRP86490.1 - 4.5e-39 133.5 0.2 4.5e-39 133.5 0.2 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 PRP86490.1 - 2.5e-29 102.4 0.1 3.7e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 PRP86490.1 - 2.8e-07 30.4 0.0 1.4e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 PRP86490.1 - 8.3e-05 22.9 0.1 3.3 8.3 0.0 3.8 3 0 0 3 3 3 2 PQQ-like domain Kdo PF06293.14 PRP86490.1 - 9.7e-05 21.8 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP86490.1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PQQ PF01011.21 PRP86490.1 - 0.00095 19.0 5.3 0.086 12.8 0.1 4.1 5 0 0 5 5 5 2 PQQ enzyme repeat APH PF01636.23 PRP86490.1 - 0.054 13.4 0.0 1.6 8.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PRP86490.1 - 0.062 12.9 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 PRP86490.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SUKH-4 PF14435.6 PRP86490.1 - 0.18 11.9 0.0 11 6.0 0.0 3.4 4 0 0 4 4 4 0 SUKH-4 immunity protein Gly_transf_sug PF04488.15 PRP86491.1 - 2.9e-23 82.3 0.1 3.1e-10 40.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PRP86491.1 - 3e-13 49.8 1.7 4.7e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 PRP86491.1 - 3.1e-08 33.3 0.1 0.00078 18.8 0.0 2.2 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Ribosomal_L10 PF00466.20 PRP86492.1 - 1.4e-21 76.5 0.4 2.2e-21 75.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 PRP86492.1 - 2.1e-21 75.7 0.0 4.1e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P ANTH PF07651.16 PRP86493.1 - 1.2e-57 195.1 2.6 1.7e-57 194.5 2.6 1.3 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 PRP86493.1 - 6.5e-11 42.4 0.1 1.6e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 ENTH domain Suf PF05843.14 PRP86494.1 - 2.1 8.2 19.4 2.4 8.0 19.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF962 PF06127.11 PRP86495.1 - 9.9e-20 70.4 0.1 2.6e-19 69.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) CcmD PF04995.14 PRP86495.1 - 0.94 9.6 4.1 1.6 8.9 0.3 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) PPR_2 PF13041.6 PRP86496.1 - 8.3e-36 121.9 24.3 2.8e-11 43.4 0.2 10.2 3 3 8 11 11 11 8 PPR repeat family PPR PF01535.20 PRP86496.1 - 1.8e-31 106.1 26.3 1.8e-06 27.8 0.2 11.0 11 1 0 11 11 10 9 PPR repeat PPR_3 PF13812.6 PRP86496.1 - 1.3e-28 98.8 8.6 2.2e-07 30.9 0.1 6.9 4 2 4 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP86496.1 - 3.8e-22 78.7 6.2 3.9e-09 36.2 0.1 3.4 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP86496.1 - 7.6e-19 67.1 2.3 4e-05 23.2 0.0 7.5 8 0 0 8 8 8 4 PPR repeat ATP13 PF12921.7 PRP86496.1 - 5.6e-06 26.2 0.3 7.1 6.5 0.0 5.8 3 2 4 7 7 7 1 Mitochondrial ATPase expression TPR_12 PF13424.6 PRP86496.1 - 0.017 15.4 1.8 3.4 8.0 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP86496.1 - 0.037 14.7 2.3 42 4.9 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat ECSIT PF06239.11 PRP86496.1 - 0.2 10.7 0.0 0.2 10.7 0.0 3.9 4 0 0 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway Clathrin PF00637.20 PRP86496.1 - 0.31 10.9 3.6 15 5.4 0.2 3.9 4 1 0 4 4 4 0 Region in Clathrin and VPS TPR_14 PF13428.6 PRP86496.1 - 0.52 11.3 4.8 62 4.8 0.0 5.8 6 2 2 8 8 6 0 Tetratricopeptide repeat Vma12 PF11712.8 PRP86496.1 - 3.6 7.7 5.5 3.6 7.6 0.0 2.8 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase BROMI PF14961.6 PRP86499.1 - 6.1e-08 30.6 16.1 8.4e-07 26.8 5.4 3.5 3 1 0 3 3 3 2 Broad-minded protein DCB PF16213.5 PRP86499.1 - 0.052 13.2 1.2 0.14 11.8 1.2 1.7 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Ras PF00071.22 PRP86500.1 - 9.7e-41 139.1 0.1 1.2e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP86500.1 - 1.8e-28 99.1 0.1 2.7e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP86500.1 - 5.1e-13 48.9 0.1 7e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP86500.1 - 0.00026 21.0 0.1 0.00099 19.2 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP86500.1 - 0.00044 19.8 0.0 0.0035 16.9 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PRP86500.1 - 0.0005 19.6 0.0 0.00085 18.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PRP86500.1 - 0.00071 19.0 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 PRP86500.1 - 0.011 15.6 0.2 0.17 11.6 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MMR_HSR1_Xtn PF16897.5 PRP86500.1 - 0.028 14.4 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 PRP86500.1 - 0.067 12.6 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein SNF2_N PF00176.23 PRP86501.1 - 9.1e-58 195.6 2.7 2.8e-47 161.1 1.6 2.7 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP86501.1 - 1.1e-12 48.2 0.0 6.5e-12 45.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 PRP86501.1 - 2e-08 33.9 10.9 2e-08 33.9 10.9 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP86501.1 - 4.5e-06 26.4 6.8 4.5e-06 26.4 6.8 2.1 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP86501.1 - 5.5e-06 26.1 10.5 5.5e-06 26.1 10.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP86501.1 - 0.00016 21.4 7.4 0.00042 20.1 7.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PRP86501.1 - 0.00037 20.8 8.9 0.00037 20.8 8.9 2.5 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 PRP86501.1 - 0.00059 19.9 8.9 0.002 18.2 8.9 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2318 PF10080.9 PRP86501.1 - 0.0018 18.3 0.4 0.0065 16.6 0.4 1.9 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) zf-RING_UBOX PF13445.6 PRP86501.1 - 0.0041 17.1 9.0 0.0041 17.1 9.0 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP86501.1 - 0.0052 16.7 8.7 0.0052 16.7 8.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 PRP86501.1 - 0.012 15.4 4.1 0.036 13.9 4.1 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 PRP86501.1 - 0.013 15.3 1.8 0.031 14.2 1.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 PRP86501.1 - 0.098 12.7 6.0 0.12 12.5 4.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PRP86501.1 - 0.11 12.8 6.3 0.34 11.2 6.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Hamartin PF04388.12 PRP86501.1 - 0.83 8.2 19.8 1.3 7.5 19.8 1.3 1 0 0 1 1 1 0 Hamartin protein zf-RING_10 PF16685.5 PRP86501.1 - 1.1 9.4 10.2 0.026 14.7 2.9 2.1 2 0 0 2 2 1 0 zinc RING finger of MSL2 DEAD_2 PF06733.15 PRP86501.1 - 6.3 6.4 10.1 0.31 10.6 0.3 3.3 2 1 0 2 2 2 0 DEAD_2 Mitofilin PF09731.9 PRP86501.1 - 9 5.0 24.4 14 4.4 24.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pkinase_Tyr PF07714.17 PRP86502.1 - 4e-57 193.5 0.8 6e-57 192.9 0.8 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86502.1 - 2.5e-45 154.9 0.7 3.8e-45 154.3 0.7 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP86502.1 - 7.4e-08 32.8 3.9 2.3e-07 31.2 3.9 2.0 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP86502.1 - 0.001 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Adeno_E1B_55K PF01696.17 PRP86502.1 - 0.0039 15.9 14.8 0.18 10.5 0.0 4.2 2 1 1 4 4 4 3 Adenovirus EB1 55K protein / large t-antigen Beta_helix PF13229.6 PRP86502.1 - 0.006 16.5 6.9 0.006 16.5 6.9 5.4 2 1 2 4 4 4 1 Right handed beta helix region Pkinase_fungal PF17667.1 PRP86502.1 - 0.12 11.1 0.8 0.8 8.4 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase CcmD PF04995.14 PRP86502.1 - 0.18 11.9 3.2 0.36 10.9 3.2 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Guanylate_cyc_2 PF09778.9 PRP86503.1 - 0.017 14.5 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 Guanylylate cyclase BTB_2 PF02214.22 PRP86504.1 - 8.5e-10 38.9 0.1 3e-09 37.1 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 PRP86504.1 - 3e-05 24.3 0.2 0.00014 22.1 0.2 2.2 1 0 0 1 1 1 1 TLD Pentapeptide_4 PF13599.6 PRP86504.1 - 1.3 9.2 16.0 1 9.6 0.1 4.9 4 2 1 5 5 5 0 Pentapeptide repeats (9 copies) Chlam_PMP PF02415.17 PRP86504.1 - 2.6 8.7 20.0 15 6.4 0.0 6.7 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Raftlin PF15250.6 PRP86506.1 - 0.1 11.3 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Raftlin MACPF PF01823.19 PRP86507.1 - 4.2e-08 33.5 0.1 8.8e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 MAC/Perforin domain SET PF00856.28 PRP86507.1 - 0.053 13.9 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 SET domain DUF5435 PF17503.2 PRP86507.1 - 0.16 11.7 0.9 0.41 10.3 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Pro-kuma_activ PF09286.11 PRP86510.1 - 6.8e-26 91.3 0.0 1.2e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain YscJ_FliF PF01514.17 PRP86510.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family Amino_oxidase PF01593.24 PRP86511.1 - 3.6e-95 319.9 0.0 5.5e-95 319.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP86511.1 - 3.2e-14 52.9 0.4 6.2e-14 52.0 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 PRP86511.1 - 2.2e-12 47.2 0.0 6.9e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain SRI PF08236.11 PRP86511.1 - 4.5e-09 36.4 6.1 1.4e-08 34.8 6.1 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Pyr_redox_2 PF07992.14 PRP86511.1 - 6.5e-08 32.2 0.1 5.4e-06 25.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP86511.1 - 1e-05 26.0 0.6 4.5e-05 23.9 0.4 2.3 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP86511.1 - 1e-05 24.8 0.5 2.8e-05 23.4 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 PRP86511.1 - 3.7e-05 23.5 2.2 3.7e-05 23.5 2.2 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PRP86511.1 - 4.6e-05 22.8 0.4 0.00016 21.0 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 PRP86511.1 - 7.7e-05 21.6 0.1 7.7e-05 21.6 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 PRP86511.1 - 0.00012 21.3 1.2 0.0011 18.2 0.4 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 PRP86511.1 - 0.00017 21.1 0.7 0.00017 21.1 0.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 PRP86511.1 - 0.0013 18.1 0.0 0.0038 16.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 PRP86511.1 - 0.0016 17.7 0.9 0.0038 16.5 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 PRP86511.1 - 0.0041 16.4 0.0 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase YjeF_N PF03853.15 PRP86511.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 YjeF-related protein N-terminus Lycopene_cycl PF05834.12 PRP86511.1 - 0.14 11.2 1.3 0.18 10.8 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 PRP86511.1 - 0.6 9.7 1.9 4.6 6.9 0.8 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Mito_carr PF00153.27 PRP86512.1 - 4.4e-71 234.9 3.4 3e-25 88.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.11 PRP86512.1 - 0.043 14.0 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Uperin family IQ PF00612.27 PRP86513.1 - 0.044 13.6 0.3 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Guanylate_cyc PF00211.20 PRP86514.1 - 3e-32 111.7 0.1 5.8e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain dCache_1 PF02743.18 PRP86514.1 - 0.00028 20.7 0.7 0.00052 19.9 0.7 1.5 1 0 0 1 1 1 1 Cache domain G8 PF10162.9 PRP86517.1 - 8.4e-24 84.0 0.8 1.9e-23 82.9 0.8 1.6 1 0 0 1 1 1 1 G8 domain His_Phos_2 PF00328.22 PRP86518.1 - 1.2e-23 84.1 0.0 9.2e-23 81.2 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Chitin_bind_1 PF00187.19 PRP86518.1 - 5.4e-11 42.8 38.3 4.6e-05 23.8 16.0 2.7 1 1 1 2 2 2 2 Chitin recognition protein RlaP PF10127.9 PRP86518.1 - 0.22 11.1 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family Ribosomal_L38e PF01781.18 PRP86519.1 - 1.3e-30 105.2 3.2 1.5e-30 105.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family LZ_Tnp_IS66 PF13007.7 PRP86519.1 - 0.085 13.6 1.2 0.17 12.7 1.2 1.5 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain Pex19 PF04614.12 PRP86520.1 - 1e-29 104.0 22.7 3.2e-29 102.4 22.7 1.9 1 1 0 1 1 1 1 Pex19 protein family DUF4487 PF14868.6 PRP86520.1 - 0.04 12.8 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) GIT1_C PF12205.8 PRP86520.1 - 0.084 13.0 1.5 0.19 11.8 1.2 1.7 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term YppG PF14179.6 PRP86520.1 - 0.13 13.0 4.9 0.29 11.9 4.9 1.6 1 0 0 1 1 1 0 YppG-like protein Phage_lysozyme2 PF18013.1 PRP86520.1 - 0.14 12.2 1.6 0.23 11.5 1.6 1.5 1 1 0 1 1 1 0 Phage tail lysozyme FKBP_N PF01346.18 PRP86520.1 - 3.6 8.6 10.5 0.2 12.6 1.0 2.8 2 2 2 4 4 4 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase YlbD_coat PF14071.6 PRP86520.1 - 6 7.1 15.7 2.1 8.6 0.4 3.2 1 1 1 3 3 3 0 Putative coat protein SNF2_N PF00176.23 PRP86521.1 - 1.1e-34 119.7 0.3 1.8e-34 119.0 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP86521.1 - 8.9e-14 51.8 0.0 6.8e-13 48.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP86521.1 - 1.8e-08 34.6 0.3 1.1e-07 32.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PRP86521.1 - 0.00035 19.9 0.0 0.00091 18.5 0.0 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 PRP86521.1 - 0.03 14.3 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain Sugar_tr PF00083.24 PRP86522.1 - 4.8e-116 388.3 34.1 5.7e-116 388.0 34.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP86522.1 - 1.7e-24 86.4 43.0 2.8e-18 66.0 21.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PRP86522.1 - 0.0014 17.0 2.3 0.0014 17.0 2.3 2.6 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Con-6 PF10346.9 PRP86524.1 - 2.5e-33 113.8 7.3 1.1e-17 63.7 0.9 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 PRP86524.1 - 0.0026 17.6 6.5 0.062 13.1 3.4 2.2 2 0 0 2 2 2 2 SpoIIIAH-like protein T3SSipB PF16535.5 PRP86524.1 - 0.016 15.7 1.3 0.02 15.4 1.3 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB CitX PF03802.14 PRP86524.1 - 0.022 14.5 0.4 0.026 14.3 0.4 1.1 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase NuA4 PF09340.10 PRP86524.1 - 0.093 12.6 6.2 1.5 8.7 1.6 2.3 1 1 1 2 2 2 0 Histone acetyltransferase subunit NuA4 YhzD PF14120.6 PRP86524.1 - 0.16 12.1 3.6 11 6.2 1.0 2.6 2 0 0 2 2 2 0 YhzD-like protein ATP-synt_DE PF00401.20 PRP86524.1 - 8.8 6.7 12.8 3.4 8.0 1.0 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PhyH PF05721.13 PRP86525.1 - 5.1e-06 26.9 0.0 2.3e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 PRP86525.1 - 4e-05 22.6 0.0 0.004 16.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Gelsolin PF00626.22 PRP86526.1 - 5.6e-19 67.8 4.7 2.5e-07 30.5 0.0 5.1 4 0 0 4 4 4 3 Gelsolin repeat C2 PF00168.30 PRP86526.1 - 1.3e-10 41.5 0.0 3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain Glyco_hydro_15 PF00723.21 PRP86527.1 - 2.2e-47 161.9 0.0 3.6e-44 151.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 UBA PF00627.31 PRP86527.1 - 2.2e-28 97.7 3.7 4.8e-14 51.9 0.1 2.9 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 PRP86527.1 - 4.9e-22 77.4 17.9 9.7e-22 76.5 17.9 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 PRP86527.1 - 1.1e-11 44.3 0.1 2.3e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA_3 PF09288.10 PRP86527.1 - 0.00033 20.4 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF1412 PF07203.11 PRP86527.1 - 0.019 15.2 0.0 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) Rad60-SLD PF11976.8 PRP86527.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SARG PF15385.6 PRP86527.1 - 6.2 5.9 8.5 12 5.0 8.5 1.3 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Kinesin PF00225.23 PRP86528.1 - 4.6e-102 341.4 0.2 4.6e-102 341.4 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP86528.1 - 3.8e-24 85.3 0.0 3.8e-24 85.3 0.0 3.0 2 1 1 3 3 3 1 Microtubule binding MSA-2c PF12238.8 PRP86528.1 - 0.69 9.9 11.1 0.12 12.4 5.9 2.4 2 0 0 2 2 2 0 Merozoite surface antigen 2c DZR PF12773.7 PRP86530.1 - 0.034 14.2 7.3 0.087 12.9 7.3 1.8 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 PRP86530.1 - 0.31 10.8 8.8 0.11 12.2 4.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 PRP86530.1 - 0.36 10.3 4.9 0.14 11.7 1.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 PRP86530.1 - 0.59 10.9 4.3 0.93 10.3 3.2 2.0 2 0 0 2 2 2 0 zinc-ribbon family TTL PF03133.15 PRP86531.1 - 1.8e-85 286.6 2.5 3.1e-85 285.9 2.5 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PRP86531.1 - 3.6e-09 36.2 0.0 0.00016 21.0 0.0 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PRP86531.1 - 2.1e-05 23.9 0.0 0.00056 19.2 0.0 2.4 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF2115 PF09888.9 PRP86531.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Cupin_4 PF08007.12 PRP86532.1 - 3.2e-18 66.3 0.0 4.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DUF5495 PF17599.2 PRP86532.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5495) HMA PF00403.26 PRP86533.1 - 4.7e-08 33.4 0.2 7.3e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain MerT PF02411.15 PRP86533.1 - 0.0054 16.8 0.5 0.0085 16.1 0.1 1.5 2 0 0 2 2 2 1 MerT mercuric transport protein Pkinase_Tyr PF07714.17 PRP86534.1 - 5.6e-26 91.4 0.0 3.8e-23 82.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86534.1 - 3.7e-08 33.1 0.0 2.9e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain CG-1 PF03859.16 PRP86536.1 - 0.093 12.5 0.2 0.84 9.4 0.1 2.2 2 0 0 2 2 2 0 CG-1 domain Pkinase PF00069.25 PRP86537.1 - 3.5e-70 236.4 0.0 9.4e-70 235.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86537.1 - 5.7e-35 120.8 0.0 7.4e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP86537.1 - 6e-05 22.5 0.0 0.00013 21.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP86537.1 - 0.00033 20.1 0.0 0.00058 19.3 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP86537.1 - 0.00098 18.8 0.8 0.004 16.8 0.1 2.2 3 0 0 3 3 3 1 RIO1 family FTA2 PF13095.6 PRP86537.1 - 0.032 13.9 0.2 2 8.0 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PRP86537.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C92 PF05708.12 PRP86538.1 - 9e-08 32.4 0.0 0.0013 18.8 0.0 2.9 3 0 0 3 3 3 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family PatG_C PF18065.1 PRP86539.1 - 0.034 14.1 0.2 0.036 14.0 0.2 1.1 1 0 0 1 1 1 0 PatG C-terminal XFP_N PF09364.10 PRP86544.1 - 1e-159 531.2 0.0 1.5e-159 530.7 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 PRP86544.1 - 6.6e-83 276.7 0.0 2.3e-82 274.9 0.0 1.9 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 PRP86544.1 - 3.5e-74 248.7 0.1 5.3e-74 248.0 0.1 1.3 1 0 0 1 1 1 1 XFP C-terminal domain Cnd1 PF12717.7 PRP86546.1 - 5.4e-08 33.0 16.7 0.00014 22.0 1.4 5.6 3 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PRP86546.1 - 4.2e-07 30.3 0.5 1.8 9.0 0.0 5.4 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 PRP86546.1 - 5.4e-07 29.3 0.8 8.7 6.9 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 PRP86546.1 - 0.0014 19.1 0.5 1.6 9.3 0.0 4.3 3 0 0 3 3 3 1 HEAT-like repeat MMS19_N PF14500.6 PRP86546.1 - 0.0022 17.6 11.0 0.011 15.4 0.3 3.7 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 PRP86546.1 - 0.032 14.4 4.3 6.7 6.9 0.1 4.7 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm_3 PF16186.5 PRP86546.1 - 0.034 13.7 0.3 0.4 10.3 0.1 2.9 2 0 0 2 2 2 0 Atypical Arm repeat Vac14_Fab1_bd PF12755.7 PRP86546.1 - 0.056 14.1 2.2 4.4 8.0 0.0 3.9 2 2 2 4 4 4 0 Vacuolar 14 Fab1-binding region RPAP3_C PF13877.6 PRP86546.1 - 0.11 13.0 6.2 13 6.4 0.1 4.8 4 0 0 4 4 4 0 Potential Monad-binding region of RPAP3 CDC27 PF09507.10 PRP86546.1 - 5 6.4 64.6 12 5.1 64.6 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CH PF00307.31 PRP86548.1 - 1.2e-63 212.1 0.0 2.3e-19 69.6 0.0 4.4 4 0 0 4 4 4 4 Calponin homology (CH) domain adh_short PF00106.25 PRP86548.1 - 1.1e-27 96.8 0.3 5.4e-14 52.1 0.0 3.5 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 PRP86548.1 - 7e-20 71.6 0.2 1.3e-10 41.2 0.0 3.4 3 1 1 4 4 4 2 Enoyl-(Acyl carrier protein) reductase CAMSAP_CH PF11971.8 PRP86548.1 - 2.5e-05 24.0 0.0 1.1 9.2 0.0 3.5 3 0 0 3 3 3 2 CAMSAP CH domain CH_2 PF06294.11 PRP86548.1 - 0.02 15.0 0.0 8.8 6.5 0.0 3.2 3 0 0 3 3 3 0 CH-like domain in sperm protein Ribosomal_L7Ae PF01248.26 PRP86549.1 - 4.4e-17 61.6 0.0 9.7e-17 60.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF2229 PF09989.9 PRP86549.1 - 0.092 12.4 2.8 1.4 8.5 0.0 2.6 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) MAP65_ASE1 PF03999.12 PRP86549.1 - 0.29 9.8 17.7 0.36 9.5 17.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Ndc1_Nup PF09531.10 PRP86549.1 - 1.6 7.3 9.0 1.6 7.3 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 PRP86549.1 - 2.3 7.7 11.3 2.8 7.4 11.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Hamartin PF04388.12 PRP86549.1 - 3.3 6.2 13.9 4 6.0 13.9 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.9 PRP86549.1 - 4.7 5.6 16.0 6.9 5.1 16.0 1.3 1 0 0 1 1 1 0 Macoilin family SOBP PF15279.6 PRP86549.1 - 4.8 7.7 12.7 5.7 7.5 12.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF913 PF06025.12 PRP86549.1 - 8.5 5.2 12.0 11 4.8 12.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MORN PF02493.20 PRP86550.1 - 5.8e-20 69.9 30.5 6.1e-08 32.1 1.8 6.5 7 0 0 7 7 7 4 MORN repeat TIP120 PF08623.10 PRP86551.1 - 9.3e-59 198.0 15.4 2.2e-57 193.5 0.0 6.3 8 1 0 8 8 8 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 PRP86551.1 - 3.9e-18 64.0 9.9 0.57 10.6 0.0 11.8 13 0 0 13 13 12 4 HEAT repeat HEAT_2 PF13646.6 PRP86551.1 - 1.1e-14 54.6 6.3 0.012 16.0 0.0 8.9 6 1 3 9 9 9 4 HEAT repeats UME PF08064.13 PRP86551.1 - 3.4e-12 46.2 1.1 0.00017 21.4 0.0 5.7 5 1 0 6 6 5 3 UME (NUC010) domain HEAT_EZ PF13513.6 PRP86551.1 - 5.7e-11 42.7 5.8 0.82 10.3 0.0 10.8 12 1 1 13 13 12 1 HEAT-like repeat MMS19_N PF14500.6 PRP86551.1 - 2.1e-05 24.3 11.8 0.0028 17.3 0.0 6.1 5 3 1 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 PRP86551.1 - 7e-05 23.0 4.7 2.7 8.2 0.0 6.6 7 1 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 PRP86551.1 - 0.00014 21.5 5.7 0.25 10.8 0.1 5.5 6 2 1 7 7 7 1 CLASP N terminal RIX1 PF08167.12 PRP86551.1 - 0.00033 20.4 13.6 0.039 13.7 0.2 5.5 4 2 0 4 4 4 2 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 PRP86551.1 - 0.00035 20.5 2.1 0.067 13.1 0.0 5.2 3 3 2 5 5 5 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 PRP86551.1 - 0.00049 20.2 12.9 0.42 10.7 0.3 6.5 5 3 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 PRP86551.1 - 0.001 19.3 0.2 6.1 7.2 0.0 4.0 4 1 0 4 4 3 2 TAF6 C-terminal HEAT repeat domain NUC173 PF08161.12 PRP86551.1 - 0.0011 18.7 0.9 3.1 7.4 0.0 4.9 3 2 1 4 4 4 1 NUC173 domain ParcG PF10274.9 PRP86551.1 - 0.017 15.3 8.1 0.64 10.1 0.1 5.2 4 2 1 6 6 6 0 Parkin co-regulated protein Sigma70_ner PF04546.13 PRP86551.1 - 0.061 13.2 3.9 0.044 13.7 0.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region V-ATPase_H_C PF11698.8 PRP86551.1 - 0.099 12.8 5.7 8.6 6.5 0.5 5.1 5 0 0 5 5 5 0 V-ATPase subunit H BID PF06393.11 PRP86551.1 - 0.26 10.8 6.9 0.34 10.4 0.1 4.0 5 1 0 5 5 5 0 BH3 interacting domain (BID) CENP-B_dimeris PF09026.10 PRP86551.1 - 3.1 8.2 11.5 10 6.6 11.5 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RhoGEF PF00621.20 PRP86552.1 - 5.9e-40 137.4 10.9 6.3e-40 137.4 7.2 2.6 2 0 0 2 2 2 1 RhoGEF domain Glyco_transf_22 PF03901.17 PRP86552.1 - 9.3e-35 120.7 33.7 1.5e-33 116.7 29.0 3.0 2 1 0 2 2 2 1 Alg9-like mannosyltransferase family TPR_1 PF00515.28 PRP86552.1 - 2.8e-15 55.4 0.1 1.1e-05 25.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PRP86552.1 - 5.2e-11 41.8 1.5 0.00091 19.2 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP86552.1 - 2.1e-06 27.5 0.1 0.0037 17.4 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP86552.1 - 5.3e-06 26.5 0.0 1.6e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP86552.1 - 2.3e-05 24.0 0.0 0.0015 18.1 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 PRP86552.1 - 5.7e-05 23.7 0.0 0.00013 22.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat IQ PF00612.27 PRP86552.1 - 0.0017 18.0 0.9 0.0083 15.8 0.9 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif TPR_6 PF13174.6 PRP86552.1 - 0.0025 18.3 0.7 1.9 9.3 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP86552.1 - 0.0037 17.8 0.1 0.014 15.9 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP86552.1 - 0.03 14.3 0.0 2.1 8.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PRP86552.1 - 0.058 13.7 1.1 0.47 10.8 0.1 2.9 2 1 0 2 2 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP86552.1 - 0.081 12.8 0.1 1.3 9.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat F_actin_bind PF08919.10 PRP86552.1 - 0.12 12.5 0.6 0.34 11.0 0.6 1.7 1 0 0 1 1 1 0 F-actin binding TPR_17 PF13431.6 PRP86552.1 - 0.14 12.6 0.0 18 6.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat COG6 PF06419.11 PRP86553.1 - 5.9e-181 602.9 0.5 6.7e-181 602.7 0.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Protoglobin PF11563.8 PRP86553.1 - 0.009 15.9 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 Protoglobin Sec34 PF04136.15 PRP86553.1 - 0.12 12.2 8.7 2 8.3 6.4 3.1 3 0 0 3 3 3 0 Sec34-like family DUF1759 PF03564.15 PRP86553.1 - 0.16 11.9 2.5 0.26 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) GIDA_assoc PF13932.6 PRP86553.1 - 0.81 9.8 5.1 1.7 8.8 5.1 1.5 1 0 0 1 1 1 0 GidA associated domain Mod_r PF07200.13 PRP86553.1 - 0.88 9.7 9.0 2.1 8.5 9.0 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein E1-E2_ATPase PF00122.20 PRP86554.1 - 2e-44 151.3 1.0 8.3e-44 149.3 0.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PRP86554.1 - 2.4e-25 90.1 1.1 4e-25 89.3 1.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PRP86554.1 - 1.2e-12 47.3 0.0 3.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PRP86554.1 - 1e-06 28.7 2.5 0.00047 20.0 0.2 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP86554.1 - 2.7e-06 27.4 0.0 5.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 PRP86554.1 - 0.039 14.4 0.0 0.088 13.2 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RA PF00788.23 PRP86555.1 - 0.0026 18.4 0.0 0.089 13.4 0.0 2.5 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain FERM_N PF09379.10 PRP86555.1 - 0.0032 17.4 0.0 4 7.4 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain RBD PF02196.15 PRP86555.1 - 0.041 14.0 0.2 1 9.5 0.0 2.7 2 0 0 2 2 2 0 Raf-like Ras-binding domain PRIMA1 PF16101.5 PRP86555.1 - 1.7 8.7 3.7 3.6 7.6 3.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AAA_12 PF13087.6 PRP86556.1 - 9.4e-18 64.6 0.0 2.8e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PRP86556.1 - 2.5e-11 43.9 0.0 1.9e-08 34.4 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 PRP86556.1 - 1.6e-09 38.2 0.0 3.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PRP86556.1 - 1.3e-05 25.0 0.0 7.7e-05 22.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain PDDEXK_1 PF12705.7 PRP86556.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily ResIII PF04851.15 PRP86556.1 - 0.0017 18.4 0.0 0.0066 16.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 PRP86556.1 - 0.0028 17.4 0.0 0.006 16.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 PRP86556.1 - 0.0051 16.4 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Cas_Cas4 PF01930.17 PRP86556.1 - 0.0054 16.9 0.3 0.067 13.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 AAA_22 PF13401.6 PRP86556.1 - 0.0061 16.8 0.0 0.024 14.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 PRP86556.1 - 0.027 14.3 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.22 PRP86556.1 - 0.03 14.7 0.1 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 PRP86556.1 - 0.044 14.2 0.0 0.23 11.8 0.0 2.2 2 0 0 2 2 1 0 AAA ATPase domain AAA PF00004.29 PRP86556.1 - 0.056 13.9 0.1 0.3 11.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 PRP86556.1 - 0.075 13.4 0.0 0.47 10.9 0.0 2.4 2 0 0 2 2 1 0 AAA domain Rpn9_C PF18261.1 PRP86556.1 - 3.9 7.1 5.9 0.52 9.9 0.5 2.4 2 0 0 2 2 1 0 Rpn9 C-terminal helix Hira PF07569.11 PRP86557.1 - 0.074 12.8 0.0 0.35 10.6 0.0 1.9 1 1 1 2 2 2 0 TUP1-like enhancer of split Ribosomal_S13 PF00416.22 PRP86558.1 - 1.2e-52 177.6 4.0 1.7e-52 177.1 4.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 MFS_1 PF07690.16 PRP86558.1 - 3e-06 26.4 9.3 3e-06 26.4 9.3 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Strabismus PF06638.11 PRP86558.1 - 0.43 9.2 4.6 0.73 8.4 4.6 1.3 1 0 0 1 1 1 0 Strabismus protein Holin_9 PF16936.5 PRP86558.1 - 3.3 7.9 8.9 0.18 12.0 2.5 2.2 2 0 0 2 2 2 0 Putative holin RRM_1 PF00076.22 PRP86559.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 PRP86560.1 - 5.2e-40 135.9 0.0 2.4e-15 56.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP86560.1 - 3.2e-33 110.0 3.5 8.8e-06 25.7 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.6 PRP86560.1 - 7.7e-32 109.3 0.9 8.6e-09 35.8 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP86560.1 - 1.1e-31 107.8 2.6 2.8e-05 24.3 0.1 5.8 5 0 0 5 5 5 5 Ankyrin repeat DHHC PF01529.20 PRP86560.1 - 3.9e-31 107.9 6.4 3.9e-31 107.9 6.4 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 PRP86560.1 - 2.4e-30 104.2 3.0 9.2e-08 32.2 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) DUF3433 PF11915.8 PRP86560.1 - 0.0029 18.0 0.1 0.048 14.1 0.0 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3433) DZR PF12773.7 PRP86560.1 - 0.52 10.4 6.4 1.1 9.3 6.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon IGFBP PF00219.18 PRP86560.1 - 1.1 10.0 7.2 2 9.1 7.2 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein ADK PF00406.22 PRP86561.1 - 4.4e-43 147.0 0.0 6e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PRP86561.1 - 1.1e-24 87.4 0.0 1.5e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 PRP86561.1 - 5.9e-18 64.6 0.2 5.9e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 PRP86561.1 - 2.9e-05 24.3 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP86561.1 - 0.00069 20.2 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 PRP86561.1 - 0.0079 16.6 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 PRP86561.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.3 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 PRP86561.1 - 0.023 14.5 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Rad17 PF03215.15 PRP86561.1 - 0.025 14.5 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 PRP86561.1 - 0.054 13.5 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PRP86561.1 - 0.12 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 PRP86561.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Pkinase_Tyr PF07714.17 PRP86562.1 - 3.1e-84 282.3 0.0 1.8e-54 184.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP86562.1 - 1.5e-75 254.0 0.0 6e-49 166.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain FHA_2 PF17913.1 PRP86562.1 - 0.0064 16.7 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain BCS1_N PF08740.11 PRP86564.1 - 1.5e-17 64.2 0.0 2.3e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 PRP86564.1 - 4.9e-16 59.4 0.0 9.3e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NUDIX PF00293.28 PRP86564.1 - 2.4e-07 30.9 0.1 6.5e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain AAA_16 PF13191.6 PRP86564.1 - 0.077 13.4 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 PRP86564.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IGPS PF00218.21 PRP86565.1 - 2.6e-80 269.2 0.3 4.9e-80 268.4 0.3 1.5 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 PRP86565.1 - 4.4e-44 150.6 0.7 1.5e-38 132.6 0.1 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase QRPTase_C PF01729.19 PRP86565.1 - 2.5e-06 27.3 0.4 0.0013 18.5 0.0 3.0 2 1 1 3 3 3 2 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 PRP86565.1 - 0.059 12.8 0.1 0.59 9.5 0.0 2.6 2 1 0 2 2 2 0 Histidine biosynthesis protein TMP-TENI PF02581.17 PRP86565.1 - 0.14 11.5 1.2 1.1 8.5 0.0 2.9 3 0 0 3 3 3 0 Thiamine monophosphate synthase Kelch_1 PF01344.25 PRP86566.1 - 5.2e-24 83.6 0.0 2.7e-08 33.3 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 PRP86566.1 - 4.9e-23 80.6 6.6 3.9e-08 33.3 0.0 5.4 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PRP86566.1 - 1.5e-13 50.5 5.6 3.3e-07 30.2 0.0 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP86566.1 - 2.1e-13 49.6 3.1 1.2e-05 25.1 0.0 5.7 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 PRP86566.1 - 1.5e-10 41.1 9.7 0.013 15.8 0.1 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP86566.1 - 1e-07 31.8 6.5 0.00077 19.4 0.1 5.6 6 0 0 6 6 6 2 Kelch motif Pkinase_Tyr PF07714.17 PRP86567.1 - 1.9e-77 260.1 0.0 2.7e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IGPD PF00475.18 PRP86567.1 - 6.3e-59 198.4 1.5 1.4e-58 197.3 1.5 1.6 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Pkinase PF00069.25 PRP86567.1 - 1.6e-51 175.3 0.0 2.6e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain REJ PF02010.15 PRP86567.1 - 9.9e-48 163.0 29.6 6e-33 114.3 5.9 4.9 5 1 0 5 5 5 3 REJ domain TIG PF01833.24 PRP86567.1 - 6.1e-07 29.4 30.4 1.1e-05 25.4 4.8 6.4 5 0 0 5 5 5 2 IPT/TIG domain Kinase-like PF14531.6 PRP86567.1 - 0.00048 19.5 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP86567.1 - 0.001 18.0 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 PRP86568.1 - 8.2e-11 42.1 0.3 2.4e-10 40.6 0.1 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 PRP86568.1 - 0.019 15.3 0.1 0.05 13.9 0.0 1.7 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain GatB_N PF02934.15 PRP86569.1 - 3.1e-109 364.6 0.0 3.9e-109 364.3 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 PRP86569.1 - 1.2e-33 116.1 0.0 2e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 GatB domain DUF5313 PF17240.2 PRP86569.1 - 0.0012 19.3 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5313) Laminin_G_3 PF13385.6 PRP86570.1 - 1.9e-29 102.8 0.1 4.1e-17 62.7 0.0 3.2 3 1 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Arm PF00514.23 PRP86570.1 - 5.3e-06 26.3 0.5 0.11 12.6 0.0 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 PRP86570.1 - 0.00013 22.0 1.7 0.0033 17.4 1.7 2.6 1 1 0 1 1 1 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 PRP86570.1 - 0.01 16.2 0.2 6.2 7.3 0.1 2.6 2 0 0 2 2 2 0 HEAT repeats RasGEF_N_2 PF14663.6 PRP86570.1 - 0.09 13.2 1.3 8.8 6.8 0.1 2.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 PRP86570.1 - 0.2 12.0 1.8 1.9 9.0 0.1 3.2 3 0 0 3 3 3 0 HEAT repeat GDI PF00996.18 PRP86571.1 - 2.7e-209 695.1 0.0 3.1e-209 694.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Mannosyl_trans PF05007.13 PRP86572.1 - 2.8e-78 263.4 22.7 2.8e-78 263.4 22.7 1.6 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 PRP86572.1 - 5.4e-11 42.2 26.6 1.3e-10 40.9 24.8 2.1 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 PRP86572.1 - 3.3e-09 36.8 2.8 3.3e-09 36.8 2.8 2.5 1 1 0 2 2 2 1 Glycosyltransferase family 87 DUF2867 PF11066.8 PRP86573.1 - 2.6e-08 34.3 0.0 6.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) Auxin_BP PF02041.16 PRP86573.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Beta_helix PF13229.6 PRP86574.1 - 3.9e-06 26.8 16.1 0.00014 21.7 8.9 3.5 1 1 1 3 3 3 2 Right handed beta helix region DUF2905 PF11146.8 PRP86574.1 - 0.052 13.7 0.5 0.21 11.8 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) NCD3G PF07562.14 PRP86574.1 - 0.42 10.6 8.6 0.21 11.6 0.2 2.8 1 1 2 3 3 3 0 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 PRP86574.1 - 1 9.2 6.3 7.1 6.5 0.6 3.0 2 0 0 2 2 2 0 Putative ephrin-receptor like DUF1565 PF07602.11 PRP86574.1 - 1.4 8.2 4.2 1.5 8.1 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) Nop14 PF04147.12 PRP86575.1 - 2.1e-200 668.2 46.5 2.5e-200 667.9 46.5 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 PRP86575.1 - 5.6e-05 22.5 0.1 5.6e-05 22.5 0.1 2.5 3 0 0 3 3 3 1 Noc2p family NCD3G PF07562.14 PRP86576.1 - 0.0057 16.6 2.4 0.0057 16.6 2.4 2.7 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR DUF1565 PF07602.11 PRP86576.1 - 0.017 14.5 12.4 0.03 13.6 2.1 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF1565) Phage_holin_3_6 PF07332.11 PRP86576.1 - 0.059 13.4 0.2 0.21 11.6 0.0 1.9 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Ephrin_rec_like PF07699.13 PRP86576.1 - 0.24 11.2 9.5 0.46 10.3 1.6 3.1 3 0 0 3 3 3 0 Putative ephrin-receptor like Ald_Xan_dh_C2 PF02738.18 PRP86577.1 - 8.1e-172 572.5 0.1 1.1e-171 572.0 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 PRP86577.1 - 2.3e-41 141.4 0.0 4.1e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 PRP86577.1 - 8e-29 100.2 0.0 1.8e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PRP86577.1 - 1.1e-28 99.0 0.0 2.4e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 PRP86577.1 - 3.3e-27 94.7 0.1 1.2e-26 92.9 0.0 2.0 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PRP86577.1 - 4.2e-06 26.6 0.2 4.2e-06 26.6 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 PRP86577.1 - 0.011 15.6 1.1 0.028 14.2 1.1 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Fer2_4 PF13510.6 PRP86577.1 - 0.24 11.5 1.2 1.9 8.6 1.2 2.4 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain START PF01852.19 PRP86578.1 - 0.0037 16.7 0.1 0.0059 16.0 0.1 1.3 1 0 0 1 1 1 1 START domain CLASP_N PF12348.8 PRP86579.1 - 0.02 14.5 0.0 0.02 14.4 0.0 1.0 1 0 0 1 1 1 0 CLASP N terminal START PF01852.19 PRP86580.1 - 8.9e-07 28.5 0.8 0.027 13.9 0.1 2.4 2 0 0 2 2 2 2 START domain Phasin PF05597.11 PRP86580.1 - 0.0052 16.8 3.1 0.94 9.5 0.4 2.8 2 0 0 2 2 2 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Trimer_CC PF08954.11 PRP86580.1 - 0.024 14.2 0.3 11 5.7 0.0 3.0 2 0 0 2 2 2 0 Trimerisation motif DUF2098 PF09871.9 PRP86580.1 - 0.034 14.5 4.5 0.37 11.2 0.3 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) HSP70 PF00012.20 PRP86580.1 - 0.035 12.3 0.0 3 5.9 0.0 2.5 2 0 0 2 2 2 0 Hsp70 protein RVT_N PF13655.6 PRP86580.1 - 0.044 14.1 0.8 18 5.7 0.1 3.0 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase HAUS4 PF14735.6 PRP86580.1 - 0.054 13.2 0.1 11 5.7 0.0 2.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 AbiEi_3 PF11459.8 PRP86580.1 - 0.059 13.1 1.7 8.2 6.1 0.1 3.1 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Polyketide_cyc PF03364.20 PRP86580.1 - 0.11 12.7 1.1 48 4.2 0.0 4.1 6 0 0 6 6 5 0 Polyketide cyclase / dehydrase and lipid transport Mto2_bdg PF12808.7 PRP86580.1 - 0.12 12.7 0.1 21 5.5 0.0 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RelE PF06296.12 PRP86580.1 - 0.14 12.3 0.4 7.6 6.7 0.1 2.5 2 0 0 2 2 2 0 RelE toxin of RelE / RelB toxin-antitoxin system SCVP PF17619.2 PRP86580.1 - 0.21 12.4 2.0 34 5.4 0.0 4.1 6 0 0 6 6 5 0 Secreted clade V proteins TetR_C_24 PF17932.1 PRP86580.1 - 0.33 11.2 5.1 25 5.2 0.0 4.3 6 0 0 6 6 6 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_53 PF07745.13 PRP86581.1 - 2.3e-06 26.9 2.4 9.7e-05 21.5 2.4 2.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 53 VRR_NUC PF08774.11 PRP86581.1 - 0.17 12.0 0.0 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 VRR-NUC domain zf_CCCH_4 PF18345.1 PRP86583.1 - 9.6e-10 38.2 16.3 6.3e-06 26.1 4.1 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 PRP86583.1 - 1.8e-09 37.1 12.8 3.1e-05 23.7 1.9 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 PRP86583.1 - 7.5e-09 35.3 11.1 0.00052 19.9 0.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 PRP86583.1 - 0.00048 20.3 3.9 0.0018 18.4 3.9 2.0 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 PRP86583.1 - 0.0038 17.7 15.9 0.17 12.4 3.1 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PRP86583.1 - 0.0097 16.6 0.9 0.0097 16.6 0.9 5.6 3 2 2 5 5 5 2 Torus domain Methyltransf_16 PF10294.9 PRP86584.1 - 3.5e-33 114.8 0.1 4.7e-33 114.4 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 PRP86584.1 - 0.028 13.7 0.2 0.092 12.1 0.1 1.7 1 1 1 2 2 2 0 rRNA small subunit methyltransferase G Ras PF00071.22 PRP86585.1 - 2.8e-55 186.4 0.1 3.2e-55 186.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP86585.1 - 2.9e-35 121.1 0.0 4.5e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP86585.1 - 9.2e-15 54.5 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP86585.1 - 3.9e-05 23.7 0.0 6.2e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP86585.1 - 0.0016 17.8 0.0 0.0022 17.4 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PRP86585.1 - 0.0028 17.6 0.3 0.073 13.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PRP86585.1 - 0.008 16.5 0.0 0.026 14.8 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP86585.1 - 0.02 15.3 0.1 0.024 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 PRP86585.1 - 0.037 14.6 0.7 0.16 12.6 0.7 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 PRP86585.1 - 0.05 13.3 0.2 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 PRP86585.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 PRP86585.1 - 0.087 12.5 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PRP86585.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF720 PF05302.11 PRP86586.1 - 0.12 12.3 0.2 0.23 11.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF720) Na_H_Exchanger PF00999.21 PRP86587.1 - 1.6e-56 191.8 41.4 2.6e-56 191.1 41.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1438 PF07270.11 PRP86588.1 - 0.19 11.8 0.6 0.28 11.3 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1438) DUF1181 PF06680.11 PRP86589.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) Peroxidase_2 PF01328.17 PRP86591.1 - 5.3e-55 186.8 0.0 6.4e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 START PF01852.19 PRP86592.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 START domain DUF1353 PF07087.11 PRP86592.1 - 0.12 12.2 0.1 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) TetR_C_24 PF17932.1 PRP86592.1 - 0.18 12.1 0.4 6.3 7.1 0.1 3.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lipase_3 PF01764.25 PRP86593.1 - 3.3e-31 108.0 0.0 6.6e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 PRP86593.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PsbJ PF01788.17 PRP86593.1 - 0.14 12.1 0.7 0.31 11.0 0.7 1.6 1 0 0 1 1 1 0 PsbJ DUF2974 PF11187.8 PRP86593.1 - 0.17 11.4 0.1 0.61 9.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) zf-4CXXC_R1 PF10497.9 PRP86594.1 - 2.1e-07 31.1 19.8 4.2e-07 30.1 19.8 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Mycoplasma_p37 PF06646.11 PRP86594.1 - 0.14 11.3 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 High affinity transport system protein p37 Homeodomain PF00046.29 PRP86595.1 - 5.6e-14 51.7 2.0 1.3e-13 50.5 2.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP86595.1 - 7.2e-05 22.6 4.7 0.00019 21.3 4.7 1.8 1 0 0 1 1 1 1 Homeobox KN domain Acetyltransf_1 PF00583.25 PRP86597.1 - 7.5e-11 42.3 0.0 1.1e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP86597.1 - 1.7e-08 34.4 0.0 1.1e-07 31.8 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP86597.1 - 4.7e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP86597.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 PRP86597.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase UCH PF00443.29 PRP86598.1 - 6.8e-21 74.9 0.0 4.7e-20 72.2 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP86598.1 - 0.0097 15.5 4.2 0.42 10.2 1.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Spc29 PF17082.5 PRP86598.1 - 0.024 14.5 0.6 0.46 10.3 0.4 2.6 2 1 1 3 3 3 0 Spindle Pole Component 29 LRR_4 PF12799.7 PRP86599.1 - 0.0046 17.3 10.0 0.1 13.1 0.5 4.9 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box_4 PF15966.5 PRP86599.1 - 0.034 14.0 0.1 0.14 12.0 0.1 2.1 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 PRP86599.1 - 0.17 11.8 1.3 0.43 10.5 1.3 1.7 1 0 0 1 1 1 0 F-box-like LON_substr_bdg PF02190.16 PRP86600.1 - 4.2e-07 30.1 0.8 5e-07 29.8 0.8 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Carb_anhydrase PF00194.21 PRP86600.1 - 0.05 13.1 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase F_actin_bund_C PF18060.1 PRP86601.1 - 1.4e-10 41.2 12.1 1.4e-10 41.2 12.1 3.5 1 1 2 3 3 3 1 F actin bundling C terminal DUF3584 PF12128.8 PRP86601.1 - 0.018 12.6 29.3 0.027 12.0 29.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FH2 PF02181.23 PRP86601.1 - 0.02 14.0 14.6 0.21 10.6 4.3 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain FliT PF05400.13 PRP86601.1 - 5.9 7.8 30.3 9.6 7.1 6.8 3.5 2 1 0 2 2 2 0 Flagellar protein FliT DUF2203 PF09969.9 PRP86601.1 - 9.2 7.0 24.1 6.2 7.6 9.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF5542 PF17696.1 PRP86606.1 - 0.062 13.4 0.7 0.12 12.5 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5542) MFS_1_like PF12832.7 PRP86607.1 - 9.7e-64 215.6 14.2 1.4e-63 215.0 14.2 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 PRP86607.1 - 9.1e-21 74.2 21.3 1.4e-20 73.5 21.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PRP86607.1 - 2.9e-12 46.3 12.2 4.3e-12 45.7 12.2 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 PRP86607.1 - 3.9e-10 39.1 13.5 2.7e-09 36.3 13.5 1.9 1 1 0 1 1 1 1 LacY proton/sugar symporter UNC-93 PF05978.16 PRP86607.1 - 0.16 11.7 3.2 0.26 11.0 2.2 1.8 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 MitMem_reg PF13012.6 PRP86608.1 - 4e-22 78.7 0.7 7e-22 78.0 0.3 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PRP86608.1 - 1.5e-19 70.1 0.0 2.6e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease WD40 PF00400.32 PRP86609.1 - 5.6e-19 68.1 6.8 5e-07 30.3 0.1 6.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP86609.1 - 3.7e-13 49.6 0.0 0.0026 18.0 0.0 6.5 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP86609.1 - 0.011 15.1 0.1 0.094 12.0 0.0 2.3 2 1 1 3 3 3 0 WD40-like domain DEK_C PF08766.11 PRP86609.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 DEK C terminal domain Lactonase PF10282.9 PRP86609.1 - 0.078 12.2 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Frtz PF11768.8 PRP86609.1 - 0.17 10.2 2.3 3.2 6.0 0.0 2.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz AT_hook PF02178.19 PRP86609.1 - 0.2 11.7 18.3 2.3 8.4 2.7 3.0 2 0 0 2 2 2 0 AT hook motif DSS1_SEM1 PF05160.13 PRP86610.1 - 2.9e-18 65.7 25.3 3.5e-18 65.4 25.3 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DNA_pol_phi PF04931.13 PRP86610.1 - 2.5 6.1 14.1 2.7 6.0 14.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 PRP86610.1 - 2.6 6.0 6.6 2.6 6.0 6.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ChaC PF04752.12 PRP86611.1 - 8e-57 192.2 0.0 1.1e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein P_C10 PF14974.6 PRP86611.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein C10 MAP65_ASE1 PF03999.12 PRP86612.1 - 1e-68 232.6 16.1 1.7e-68 231.8 15.4 1.8 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) UvsY PF11056.8 PRP86612.1 - 0.088 13.1 1.2 0.24 11.8 1.2 1.7 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY DUF3490 PF11995.8 PRP86612.1 - 0.73 9.6 4.5 0.91 9.3 0.1 3.3 2 2 2 4 4 4 0 Domain of unknown function (DUF3490) TLD PF07534.16 PRP86613.1 - 1.7e-05 25.1 0.1 8.7e-05 22.8 0.0 2.0 1 1 0 2 2 2 1 TLD Thioredoxin_7 PF13899.6 PRP86614.1 - 3.1e-12 46.5 0.0 8.2e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 PRP86614.1 - 1.7e-11 44.2 0.1 4e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 PRP86614.1 - 2.3e-10 40.1 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 PRP86614.1 - 0.00085 18.9 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain PPP4R2 PF09184.11 PRP86614.1 - 0.007 16.0 22.5 0.011 15.4 22.5 1.3 1 0 0 1 1 1 1 PPP4R2 Caldesmon PF02029.15 PRP86614.1 - 0.011 14.5 34.5 0.015 14.1 34.5 1.1 1 0 0 1 1 1 0 Caldesmon UIM PF02809.20 PRP86614.1 - 0.04 13.8 1.1 0.11 12.5 1.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif DDHD PF02862.17 PRP86614.1 - 0.052 13.7 8.8 0.14 12.3 8.8 1.7 1 0 0 1 1 1 0 DDHD domain DUF2828 PF11443.8 PRP86614.1 - 0.48 8.5 14.2 0.68 7.9 14.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RNA_pol_Rpc4 PF05132.14 PRP86614.1 - 0.54 10.7 17.7 1.2 9.6 17.7 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPR3 PF03666.13 PRP86614.1 - 0.61 8.8 19.5 0.85 8.3 19.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 PRP86614.1 - 0.73 8.5 18.3 0.88 8.3 18.3 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 PRP86614.1 - 0.78 9.5 28.5 1.2 8.9 28.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 PRP86614.1 - 0.85 7.8 26.2 1.1 7.4 26.2 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 PRP86614.1 - 1.9 8.7 15.8 3.2 7.9 15.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Tim54 PF11711.8 PRP86614.1 - 2.4 6.8 21.6 0.48 9.1 17.9 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DDRGK PF09756.9 PRP86614.1 - 2.8 7.5 36.0 5 6.7 36.0 1.4 1 0 0 1 1 1 0 DDRGK domain Hid1 PF12722.7 PRP86614.1 - 3.4 5.7 19.3 4.6 5.2 19.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2981 PF11200.8 PRP86614.1 - 4.1 7.1 9.7 6.1 6.5 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) NARP1 PF12569.8 PRP86614.1 - 4.1 6.2 26.6 5.7 5.7 26.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF913 PF06025.12 PRP86614.1 - 5.1 6.0 13.5 7.3 5.4 13.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4045 PF13254.6 PRP86614.1 - 5.7 6.5 26.9 8.8 5.8 26.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3306 PF11748.8 PRP86614.1 - 7.1 7.5 20.5 43 5.0 16.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) MCM_bind PF09739.9 PRP86614.1 - 8 4.8 18.6 12 4.2 18.6 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Borrelia_P83 PF05262.11 PRP86614.1 - 8.1 4.8 31.7 13 4.1 31.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Pox_Ag35 PF03286.14 PRP86614.1 - 8.4 6.1 26.9 15 5.3 26.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Bromodomain PF00439.25 PRP86615.1 - 5.8e-19 68.0 0.1 1.2e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 PRP86615.1 - 4.5e-09 36.1 3.8 4.5e-09 36.1 3.8 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 PRP86615.1 - 6.8e-06 25.5 0.7 6.8e-06 25.5 0.7 2.6 3 0 0 3 3 3 1 PHD-finger zf-ANAPC11 PF12861.7 PRP86615.1 - 0.016 15.3 0.4 0.034 14.2 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 PRP86615.1 - 0.03 14.6 4.0 0.062 13.6 4.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-HC5HC2H PF13771.6 PRP86615.1 - 0.049 13.9 1.3 0.13 12.5 1.3 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-4CXXC_R1 PF10497.9 PRP86616.1 - 3e-08 33.8 19.6 6.6e-08 32.7 19.6 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF812 PF05667.11 PRP86616.1 - 1.1e-06 27.8 5.8 1.3e-06 27.7 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Rrn6 PF10214.9 PRP86616.1 - 7.7e-05 21.4 4.6 8.6e-05 21.3 4.6 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spc7 PF08317.11 PRP86616.1 - 0.0055 15.6 7.6 0.0081 15.1 7.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_23 PF13476.6 PRP86616.1 - 0.012 16.1 2.1 0.016 15.7 2.1 1.2 1 0 0 1 1 1 0 AAA domain Bac_GDH PF05088.12 PRP86616.1 - 0.013 13.0 2.0 0.016 12.8 2.0 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase WDCP PF15390.6 PRP86616.1 - 0.035 12.5 3.0 0.039 12.4 3.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family OmpH PF03938.14 PRP86616.1 - 0.056 13.8 11.5 0.095 13.0 11.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GAS PF13851.6 PRP86616.1 - 0.058 12.7 10.4 0.088 12.1 10.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 PRP86616.1 - 0.083 13.0 10.5 0.15 12.1 10.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tho2 PF11262.8 PRP86616.1 - 0.099 11.8 3.7 0.14 11.3 3.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Rho_Binding PF08912.11 PRP86616.1 - 0.11 13.3 8.8 0.77 10.6 4.6 2.6 2 0 0 2 2 2 0 Rho Binding Phage_GPO PF05929.11 PRP86616.1 - 0.14 11.8 6.6 0.17 11.5 5.3 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ZapB PF06005.12 PRP86616.1 - 0.15 12.5 12.5 0.15 12.6 10.7 1.9 1 1 1 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 PRP86616.1 - 0.16 9.9 6.2 0.2 9.5 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.6 PRP86616.1 - 0.19 11.8 9.6 0.33 11.1 9.6 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 ATG16 PF08614.11 PRP86616.1 - 0.22 11.7 15.4 0.51 10.5 15.4 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Thioredoxin_15 PF18403.1 PRP86616.1 - 0.28 11.1 3.4 0.81 9.6 2.6 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain DUF4795 PF16043.5 PRP86616.1 - 0.35 10.4 10.4 0.6 9.7 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) APG6_N PF17675.1 PRP86616.1 - 0.6 10.6 16.3 1.5 9.4 16.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region ERM PF00769.19 PRP86616.1 - 0.61 9.9 15.2 0.12 12.2 11.7 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family GPS2_interact PF15784.5 PRP86616.1 - 2.2 8.8 10.1 0.35 11.3 5.8 2.0 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain TMF_DNA_bd PF12329.8 PRP86616.1 - 3 7.9 11.5 6.7 6.8 11.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HemX PF04375.14 PRP86616.1 - 3.8 6.7 13.8 5.3 6.2 13.8 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Tup_N PF08581.10 PRP86616.1 - 5.8 7.3 14.7 1.6 9.0 2.9 3.1 2 1 1 3 3 3 0 Tup N-terminal TMPIT PF07851.13 PRP86616.1 - 6.8 5.8 7.9 9.9 5.3 7.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein HMG_box PF00505.19 PRP86617.1 - 3.8e-43 145.7 14.5 1.7e-22 79.6 1.6 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 PRP86617.1 - 7.2e-29 100.2 15.1 2.5e-14 53.6 2.9 2.4 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 PRP86617.1 - 0.006 16.5 1.5 0.66 10.0 0.0 2.6 3 0 0 3 3 3 2 CHDNT (NUC034) domain Ccdc124 PF06244.12 PRP86617.1 - 0.036 14.6 12.9 0.11 13.0 0.2 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 Protamine_like PF06382.11 PRP86617.1 - 4.8 7.4 9.4 0.45 10.7 2.4 2.4 1 1 0 2 2 2 0 Protamine and protamine like RRM_1 PF00076.22 PRP86618.1 - 3.6e-32 110.0 0.5 9e-15 54.3 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP86618.1 - 1e-05 25.5 0.0 0.00026 21.0 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif Ras PF00071.22 PRP86619.1 - 1e-59 200.8 0.2 1.5e-59 200.2 0.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP86619.1 - 8.6e-34 116.3 0.6 1.3e-33 115.7 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP86619.1 - 1.1e-16 60.8 0.1 3.3e-16 59.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Ribonuc_L-PSP PF01042.21 PRP86619.1 - 6.1e-11 42.4 0.1 2.9e-09 37.0 0.1 2.5 2 1 0 2 2 2 1 Endoribonuclease L-PSP GTP_EFTU PF00009.27 PRP86619.1 - 4.2e-06 26.4 0.1 2.7e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP86619.1 - 0.00018 21.5 0.0 0.00051 20.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP86619.1 - 0.00062 19.2 0.0 0.00098 18.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 PRP86619.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 PRP86619.1 - 0.0017 17.8 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PRP86619.1 - 0.026 14.4 0.0 0.41 10.5 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase AA_permease_2 PF13520.6 PRP86621.1 - 7.1e-49 166.8 54.3 7.1e-49 166.8 54.3 1.6 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 PRP86621.1 - 3.3e-39 134.8 51.3 3.3e-39 134.8 51.3 1.8 1 1 1 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 PRP86621.1 - 3.3e-17 62.3 6.8 3.3e-17 62.3 6.8 5.1 5 0 0 5 5 5 1 C-terminus of AA_permease FA_hydroxylase PF04116.13 PRP86621.1 - 0.23 11.8 0.1 0.23 11.8 0.1 3.3 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily SPC25 PF06703.11 PRP86621.1 - 1.1 9.1 7.8 3.3 7.5 0.6 3.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Spore_permease PF03845.13 PRP86621.1 - 2.2 7.1 35.4 0.042 12.7 20.4 3.8 3 1 0 3 3 3 0 Spore germination protein DUF1634 PF07843.11 PRP86621.1 - 5.5 7.1 12.3 12 6.0 1.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1634) PhoLip_ATPase_C PF16212.5 PRP86622.1 - 5.4e-76 255.6 25.4 5.4e-76 255.6 25.4 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP86622.1 - 3.8e-25 87.4 4.0 3.8e-25 87.4 4.0 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 PRP86622.1 - 4.9e-13 49.0 0.0 6.1e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PRP86622.1 - 1.7e-11 44.8 0.1 0.012 15.9 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 PRP86622.1 - 1.1e-06 28.3 0.1 4.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PRP86622.1 - 0.0018 18.1 2.5 0.0058 16.4 0.2 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1811 PF08838.10 PRP86622.1 - 0.025 14.8 1.2 2.3 8.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1811) HAD PF12710.7 PRP86622.1 - 0.054 13.9 0.0 13 6.1 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SAP30_Sin3_bdg PF13867.6 PRP86623.1 - 3.3e-14 53.0 0.3 4.7e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 LRR_8 PF13855.6 PRP86624.1 - 7.3e-07 28.9 12.7 0.0012 18.5 6.9 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PRP86624.1 - 3.9e-06 27.1 13.9 0.0085 16.5 4.2 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 PRP86624.1 - 6.6e-06 26.5 0.0 3e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP86624.1 - 4.2e-05 22.8 0.1 0.32 10.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP86624.1 - 8e-05 22.3 0.2 0.19 11.7 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PRP86624.1 - 0.022 14.6 1.1 2 8.3 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain pair LRR_6 PF13516.6 PRP86624.1 - 0.042 13.9 4.7 0.58 10.4 1.5 3.0 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 PRP86624.1 - 0.19 12.4 14.5 0.8 10.5 0.7 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat PIN_4 PF13638.6 PRP86626.1 - 1.4e-08 35.1 1.1 7.7e-08 32.7 0.1 2.7 2 0 0 2 2 2 1 PIN domain DUF1160 PF06648.11 PRP86626.1 - 0.00033 20.7 0.2 0.015 15.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1160) LRR_6 PF13516.6 PRP86626.1 - 0.0035 17.3 0.2 1.4 9.2 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat RasGEF PF00617.19 PRP86627.1 - 7.5e-47 159.8 1.2 7.5e-47 159.8 1.2 1.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP86627.1 - 0.063 13.5 0.2 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 RasGEF N-terminal motif DUF4719 PF15843.5 PRP86627.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) SAP PF02037.27 PRP86629.1 - 7.1e-08 32.0 2.1 0.00015 21.4 0.0 3.6 3 0 0 3 3 3 2 SAP domain SBDS PF01172.18 PRP86630.1 - 7.4e-18 64.4 0.0 9.4e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_L4 PF00573.22 PRP86631.1 - 2.4e-38 131.7 0.2 4.2e-38 131.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 PRP86631.1 - 1.2e-21 76.5 1.8 1.2e-21 76.5 1.8 2.4 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DIM1 PF02966.16 PRP86632.1 - 6.5e-47 158.6 0.0 7.6e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 PRP86632.1 - 0.034 14.1 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF4768 PF15989.5 PRP86632.1 - 0.058 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) RRM_1 PF00076.22 PRP86633.1 - 1.7e-08 34.2 0.3 4.3e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PRP86633.1 - 1.3e-05 25.0 0.1 3.4e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PRP86633.1 - 2.9e-05 24.0 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Galanin PF01296.18 PRP86633.1 - 0.024 14.6 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Galanin Grg1 PF11034.8 PRP86633.1 - 0.024 14.9 12.9 0.32 11.3 1.3 2.8 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 Cyt_b-c1_8 PF10890.8 PRP86633.1 - 0.042 14.3 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 RRM_3 PF08777.11 PRP86633.1 - 0.085 12.9 2.2 0.15 12.1 0.0 2.4 2 1 1 3 3 3 0 RNA binding motif GldM_N PF12081.8 PRP86633.1 - 1.5 8.8 13.0 0.16 12.1 4.6 2.4 1 1 1 2 2 2 0 GldM N-terminal domain TatD_DNase PF01026.21 PRP86635.1 - 1.5e-49 168.7 0.0 2.2e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase COX7a PF02238.15 PRP86635.1 - 0.023 15.1 0.1 0.039 14.3 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII Amidohydro_2 PF04909.14 PRP86635.1 - 0.029 14.2 0.0 0.31 10.8 0.0 2.6 1 1 0 1 1 1 0 Amidohydrolase DUF4976 PF16347.5 PRP86635.1 - 0.11 12.8 0.3 1.4 9.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4976) Sugar_tr PF00083.24 PRP86636.1 - 1.1e-48 166.3 16.8 1.4e-48 165.9 16.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP86636.1 - 1e-22 80.6 28.0 4.9e-15 55.3 9.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 PRP86636.1 - 9.4e-08 31.7 1.6 2.4e-07 30.4 1.6 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 PRP86636.1 - 0.0003 19.2 2.9 0.0003 19.2 2.9 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4131 PF13567.6 PRP86636.1 - 0.0025 17.5 3.6 3.2 7.4 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4131) DUF3151 PF11349.8 PRP86637.1 - 0.00033 20.8 0.1 0.31 11.2 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3151) Cation_efflux PF01545.21 PRP86638.1 - 4.8e-26 91.7 9.7 6e-26 91.4 9.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 PRP86638.1 - 3.1e-11 43.3 0.0 6.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF1129 PF06570.11 PRP86638.1 - 0.0017 17.9 0.2 0.0026 17.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF2207 PF09972.9 PRP86638.1 - 0.032 13.0 0.6 0.065 12.0 0.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1700 PF08006.11 PRP86638.1 - 2.5 7.6 5.7 11 5.5 1.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) D123 PF07065.14 PRP86639.1 - 1.8e-20 73.3 0.8 3.4e-19 69.1 0.8 2.4 1 1 0 1 1 1 1 D123 R2K_3 PF14243.6 PRP86639.1 - 4.7e-06 26.8 0.0 6.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 PRP86639.1 - 7.4e-06 25.9 0.1 4e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 2 UPF0061 PF02696.14 PRP86639.1 - 0.013 14.3 0.2 0.018 13.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family ATP-grasp_3 PF02655.14 PRP86639.1 - 0.17 11.9 0.4 0.59 10.2 0.1 2.0 2 1 0 2 2 2 0 ATP-grasp domain XRN_N PF03159.18 PRP86640.1 - 2.3e-62 210.6 0.4 2.8e-61 207.0 0.0 2.9 3 1 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PRP86640.1 - 2.8e-43 148.5 0.0 7.6e-24 84.5 0.0 2.4 2 0 0 2 2 2 2 Xrn1 helical domain PITH PF06201.13 PRP86640.1 - 1.6e-22 80.3 0.4 2.8e-22 79.6 0.4 1.4 1 0 0 1 1 1 1 PITH domain Ank_2 PF12796.7 PRP86641.1 - 0.015 15.9 0.0 0.58 10.8 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) SNF2_N PF00176.23 PRP86642.1 - 5.3e-58 196.4 2.2 8.9e-58 195.7 2.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP86642.1 - 3.3e-22 78.9 0.5 5.1e-20 71.9 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP86642.1 - 1.4e-10 41.5 0.1 1.4e-10 41.5 0.1 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PRP86642.1 - 3e-07 29.9 0.0 3e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 PRP86642.1 - 1.1e-06 28.6 0.6 6.4e-06 26.0 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Gelsolin PF00626.22 PRP86643.1 - 9.2e-34 115.2 0.0 1.3e-13 50.6 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat C2 PF00168.30 PRP86643.1 - 9.1e-15 54.8 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain rve_3 PF13683.6 PRP86644.1 - 0.033 14.0 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Integrase core domain Glyoxalase PF00903.25 PRP86645.1 - 7.5e-45 152.2 0.3 1.8e-21 76.7 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PRP86645.1 - 1.2e-18 67.3 0.1 1.3e-08 35.1 0.0 3.4 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PRP86645.1 - 3.7e-09 37.3 0.0 0.0021 18.8 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 PRP86645.1 - 6e-09 35.8 0.7 0.041 13.8 0.1 4.3 4 1 0 4 4 4 3 Glyoxalase-like domain Glyoxalase_3 PF13468.6 PRP86645.1 - 3e-06 27.5 0.0 0.2 11.7 0.0 3.7 2 2 1 3 3 3 2 Glyoxalase-like domain MoaF PF10703.9 PRP86645.1 - 0.00041 20.3 0.0 0.07 13.1 0.0 2.5 2 0 0 2 2 2 1 MoaF N-terminal domain CppA_N PF14506.6 PRP86645.1 - 0.0087 16.1 0.0 3.6 7.7 0.0 2.3 2 0 0 2 2 2 2 CppA N-terminal CppA_C PF14507.6 PRP86645.1 - 0.017 15.9 0.3 9 7.1 0.0 2.3 2 0 0 2 2 2 0 CppA C-terminal RA PF00788.23 PRP86645.1 - 0.044 14.4 0.0 0.97 10.1 0.0 2.8 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain DUF1338 PF07063.13 PRP86645.1 - 0.15 11.2 0.0 67 2.5 0.0 3.2 2 2 0 3 3 3 0 Domain of unknown function (DUF1338) MitoNEET_N PF10660.9 PRP86647.1 - 0.071 13.1 0.3 0.37 10.8 0.2 2.2 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Neur_chan_LBD PF02931.23 PRP86648.1 - 0.022 14.2 0.1 1 8.8 0.0 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel ligand binding domain DUF2222 PF09984.9 PRP86648.1 - 0.079 12.9 0.6 0.15 11.9 0.6 1.4 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) TrbL PF04610.14 PRP86648.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein MitoNEET_N PF10660.9 PRP86648.1 - 0.17 11.9 0.2 0.4 10.7 0.2 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Glyco_hydro_76 PF03663.14 PRP86649.1 - 6.5e-20 72.0 19.6 9e-20 71.5 19.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 F-box-like PF12937.7 PRP86651.1 - 1.8e-08 34.2 0.4 5.2e-08 32.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP86651.1 - 0.00065 19.5 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain UBA PF00627.31 PRP86651.1 - 0.021 14.7 0.1 0.085 12.8 0.1 2.1 1 1 0 1 1 1 0 UBA/TS-N domain Ras PF00071.22 PRP86653.1 - 8.3e-57 191.3 0.8 2.5e-56 189.7 0.2 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP86653.1 - 5.5e-33 113.7 0.0 1.1e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP86653.1 - 9.8e-13 47.9 0.1 1.3e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP86653.1 - 6.7e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP86653.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PRP86653.1 - 0.00097 18.7 0.2 0.0015 18.1 0.2 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PRP86653.1 - 0.0014 18.1 0.5 0.0042 16.5 0.0 1.9 2 1 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PRP86653.1 - 0.0044 17.4 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PRP86653.1 - 0.0092 16.3 0.1 0.12 12.7 0.0 2.5 1 1 2 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 PRP86653.1 - 0.01 15.7 1.0 1.2 9.0 0.1 2.4 1 1 1 2 2 2 0 RsgA GTPase TniB PF05621.11 PRP86653.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 PRP86653.1 - 0.036 14.0 0.2 0.12 12.3 0.2 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 PRP86653.1 - 0.059 13.1 0.3 0.36 10.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 PRP86653.1 - 0.08 12.3 0.3 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 PRP86653.1 - 0.094 13.3 0.7 4.2 7.9 0.0 2.3 1 1 0 2 2 2 0 AAA domain IML1 PF12257.8 PRP86654.1 - 1.3e-102 342.8 0.0 2.1e-102 342.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 PrmA PF06325.13 PRP86654.1 - 0.06 12.7 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Tugs PF17840.1 PRP86655.1 - 1.7e-05 24.9 0.1 4.1e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Tethering Ubl4a to BAGS domain zf-RING_2 PF13639.6 PRP86656.1 - 3.4e-06 27.3 8.2 9.9e-06 25.8 8.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP86656.1 - 0.00014 21.6 5.7 0.00035 20.4 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP86656.1 - 0.00023 21.4 7.3 0.00075 19.7 7.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF3430 PF11912.8 PRP86656.1 - 0.001 19.1 15.8 0.0021 18.2 15.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Zn_ribbon_17 PF17120.5 PRP86656.1 - 0.0022 17.6 5.9 0.0022 17.6 5.9 1.9 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type Rootletin PF15035.6 PRP86656.1 - 0.0026 17.8 1.6 0.0051 16.9 1.6 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 PRP86656.1 - 0.0076 16.9 4.8 0.5 11.0 4.1 2.5 2 0 0 2 2 2 1 Initiation control protein YabA bZIP_1 PF00170.21 PRP86656.1 - 0.01 15.9 5.8 0.028 14.5 5.8 1.7 1 0 0 1 1 1 0 bZIP transcription factor zf-C3HC4_2 PF13923.6 PRP86656.1 - 0.018 14.9 8.5 0.046 13.6 8.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP86656.1 - 0.044 13.6 6.3 0.11 12.4 6.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 bZIP_2 PF07716.15 PRP86656.1 - 0.072 13.2 1.0 0.15 12.1 1.0 1.5 1 0 0 1 1 1 0 Basic region leucine zipper zf-RING_5 PF14634.6 PRP86656.1 - 0.12 12.4 8.5 0.37 10.8 8.5 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 PRP86656.1 - 0.18 11.9 5.7 0.5 10.4 5.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 PRP86656.1 - 0.2 11.7 5.2 0.76 9.9 5.2 2.0 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-RING_4 PF14570.6 PRP86656.1 - 0.23 11.3 5.0 0.51 10.2 5.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Gly-zipper_OmpA PF13436.6 PRP86656.1 - 0.33 10.8 7.6 0.69 9.7 7.6 1.5 1 0 0 1 1 1 0 Glycine-zipper domain zf-C3HC4 PF00097.25 PRP86656.1 - 0.41 10.5 8.7 1.1 9.2 8.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-H PF05837.12 PRP86656.1 - 0.55 10.7 5.4 1.3 9.5 5.4 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 PRP86656.1 - 0.56 10.7 5.7 1.2 9.7 5.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region TMCO5 PF14992.6 PRP86656.1 - 0.73 9.4 5.4 1.4 8.5 5.4 1.3 1 0 0 1 1 1 0 TMCO5 family zf-C3HC4_4 PF15227.6 PRP86656.1 - 1.2 9.4 3.9 3.5 7.8 3.9 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ACBP PF00887.19 PRP86657.1 - 1.9e-26 92.1 1.5 2.6e-26 91.7 0.3 1.9 2 0 0 2 2 2 1 Acyl CoA binding protein Methyltransf_25 PF13649.6 PRP86657.1 - 5.7e-06 26.9 0.0 4.1e-05 24.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP86657.1 - 7.3e-05 22.2 0.0 0.00057 19.3 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 PRP86657.1 - 0.0023 18.5 0.0 0.008 16.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP86657.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TrmB PF01978.19 PRP86657.1 - 0.097 12.6 0.2 0.31 11.0 0.2 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Methyltransf_31 PF13847.6 PRP86657.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 PRP86657.1 - 0.11 13.2 0.0 0.35 11.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Glyco_transf_49 PF13896.6 PRP86658.1 - 1.3e-14 54.3 0.1 2.3e-06 27.2 0.0 3.1 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan Pkinase_Tyr PF07714.17 PRP86659.1 - 1e-55 188.9 0.0 2e-55 187.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86659.1 - 7.6e-47 159.9 0.0 1.6e-46 158.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 PRP86659.1 - 9.3e-05 22.5 0.0 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP86659.1 - 0.00032 19.7 0.1 0.0012 17.9 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PRP86659.1 - 0.01 15.4 0.1 0.035 13.7 0.0 1.9 1 1 0 2 2 2 0 RIO1 family Kdo PF06293.14 PRP86659.1 - 0.026 13.9 0.0 0.069 12.5 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP86659.1 - 0.057 12.2 0.0 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 PRP86659.1 - 0.072 12.7 0.1 2.2 7.9 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_C14 PF00656.22 PRP86660.1 - 1.7e-55 188.7 0.0 2.2e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain GST_C PF00043.25 PRP86662.1 - 6e-07 29.6 0.0 1.4e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP86662.1 - 0.00022 21.2 0.0 0.00055 19.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PSD2 PF07624.11 PRP86662.1 - 0.00094 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1585) GST_C_3 PF14497.6 PRP86662.1 - 0.0073 16.5 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PH PF00169.29 PRP86662.1 - 0.016 15.7 0.1 0.042 14.4 0.1 1.7 1 0 0 1 1 1 0 PH domain MIF4G PF02854.19 PRP86663.1 - 3.4e-45 154.3 3.3 4.7e-45 153.8 0.9 2.1 2 0 0 2 2 2 1 MIF4G domain VWA_3 PF13768.6 PRP86663.1 - 9.7e-27 93.8 0.4 8e-25 87.6 0.0 3.5 4 0 0 4 4 4 1 von Willebrand factor type A domain VIT PF08487.10 PRP86663.1 - 5.8e-17 61.9 0.0 1.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain MA3 PF02847.17 PRP86663.1 - 6.3e-14 51.9 1.5 1.7e-12 47.3 0.5 3.1 2 0 0 2 2 2 1 MA3 domain VWA PF00092.28 PRP86663.1 - 2.2e-12 47.5 0.0 5.2e-11 43.1 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP86663.1 - 7.5e-10 39.4 0.1 7.3e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 PRP86663.1 - 1.6e-05 24.7 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain RSN1_7TM PF02714.15 PRP86664.1 - 4.4e-38 131.2 21.9 4.4e-38 131.2 21.9 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PRP86664.1 - 6.4e-26 91.0 5.5 6.4e-26 91.0 5.5 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PRP86664.1 - 3.5e-21 76.2 0.0 5.4e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter LRR_6 PF13516.6 PRP86665.1 - 2.8e-36 120.5 21.3 1.8e-05 24.4 0.1 9.1 9 0 0 9 9 9 8 Leucine Rich repeat LRR_4 PF12799.7 PRP86665.1 - 2.3e-13 50.1 4.8 0.002 18.5 0.0 4.8 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP86665.1 - 3.5e-10 39.5 4.8 0.026 14.3 0.0 5.6 6 1 0 6 6 6 4 Leucine rich repeat LRR_1 PF00560.33 PRP86665.1 - 0.0016 18.7 4.9 69 4.6 0.0 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat HHH_2 PF12826.7 PRP86665.1 - 0.025 14.7 0.0 41 4.4 0.0 3.7 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF4366 PF14283.6 PRP86666.1 - 0.0031 17.6 0.3 0.0031 17.6 0.3 3.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4366) TFIIA PF03153.13 PRP86666.1 - 9 6.2 18.7 14 5.5 18.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_1 PF01148.20 PRP86667.1 - 0.15 11.8 21.2 0.44 10.3 19.5 2.5 1 1 0 1 1 1 0 Cytidylyltransferase family F-box PF00646.33 PRP86668.1 - 0.026 14.4 1.3 0.053 13.4 0.4 2.0 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 PRP86668.1 - 0.028 14.3 1.7 0.078 12.9 0.4 2.3 2 0 0 2 2 2 0 F-box-like EI24 PF07264.11 PRP86669.1 - 2.8e-15 57.0 0.3 6.5e-07 29.8 0.0 2.3 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Myelin_PLP PF01275.19 PRP86669.1 - 0.064 13.1 5.8 0.44 10.4 0.0 2.4 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) Cbl_N2 PF02761.14 PRP86671.1 - 1.3e-10 41.8 0.0 3.6e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2 PF00017.24 PRP86671.1 - 4.9e-10 39.4 0.4 8.5e-07 29.0 0.0 2.7 2 0 0 2 2 2 2 SH2 domain TMCO5 PF14992.6 PRP86671.1 - 0.0038 16.8 1.4 0.0068 16.0 1.4 1.3 1 0 0 1 1 1 1 TMCO5 family Nnf1 PF03980.14 PRP86671.1 - 0.005 17.2 0.5 1.8 9.0 1.7 3.4 3 0 0 3 3 3 1 Nnf1 Tropomyosin PF00261.20 PRP86671.1 - 0.0085 15.5 2.2 0.019 14.4 2.2 1.6 1 0 0 1 1 1 1 Tropomyosin Tektin PF03148.14 PRP86671.1 - 0.012 14.4 6.6 0.039 12.7 3.3 2.2 2 0 0 2 2 2 0 Tektin family Fib_alpha PF08702.10 PRP86671.1 - 0.021 15.0 4.2 0.026 14.7 2.6 2.0 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 PRP86671.1 - 0.029 14.3 2.3 0.1 12.6 2.3 2.0 1 0 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.12 PRP86671.1 - 0.044 13.8 1.9 0.1 12.6 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 PRP86671.1 - 0.045 14.0 4.4 0.12 12.6 4.4 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CdvA PF18822.1 PRP86671.1 - 0.046 13.5 5.0 0.14 12.0 5.0 1.7 1 0 0 1 1 1 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 PRP86671.1 - 0.078 13.4 1.1 0.22 12.0 0.7 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Sec2p PF06428.11 PRP86671.1 - 0.093 12.7 4.1 5.6 7.0 4.0 2.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p T3SSipB PF16535.5 PRP86671.1 - 0.13 12.7 2.6 0.093 13.2 0.7 1.7 2 0 0 2 2 1 0 Type III cell invasion protein SipB IBP39 PF11422.8 PRP86671.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Initiator binding protein 39 kDa UPF0242 PF06785.11 PRP86671.1 - 0.18 11.9 2.0 0.33 11.0 2.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 PRP86671.1 - 0.18 11.9 5.1 0.11 12.6 2.6 1.9 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein CREPT PF16566.5 PRP86671.1 - 0.2 11.9 6.0 0.16 12.1 2.8 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DivIC PF04977.15 PRP86671.1 - 0.24 11.2 2.4 0.49 10.2 1.7 1.9 1 1 0 1 1 1 0 Septum formation initiator Exonuc_VII_L PF02601.15 PRP86671.1 - 0.28 10.7 1.7 0.26 10.8 0.5 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1515 PF07439.11 PRP86671.1 - 0.39 10.8 2.9 0.55 10.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) APG6_N PF17675.1 PRP86671.1 - 0.52 10.8 4.2 1.7 9.2 4.2 1.8 1 0 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 PRP86671.1 - 0.54 10.6 6.3 0.37 11.2 4.2 1.8 2 0 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 PRP86671.1 - 1.1 9.7 6.3 0.18 12.3 1.6 2.0 2 1 0 2 2 2 0 Fez1 XhlA PF10779.9 PRP86671.1 - 3.6 7.9 4.7 32 4.8 4.5 2.4 1 1 1 2 2 2 0 Haemolysin XhlA BTB_2 PF02214.22 PRP86672.1 - 3.9e-18 65.6 0.0 7.6e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 PRP86672.1 - 6.3e-14 52.4 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 TLD BTB PF00651.31 PRP86672.1 - 0.0014 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 PRP86672.1 - 0.0034 17.5 0.0 0.0068 16.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Mannosyl_trans3 PF11051.8 PRP86673.1 - 1.1e-36 126.6 0.0 2.2e-36 125.7 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative DUF4131 PF13567.6 PRP86673.1 - 0.028 14.1 0.3 0.054 13.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PI3_PI4_kinase PF00454.27 PRP86674.1 - 3.3e-52 177.8 1.1 1.9e-51 175.3 1.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PRP86674.1 - 9.6e-42 142.5 1.0 1.8e-41 141.6 1.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 PRP86674.1 - 3e-14 53.1 0.0 7e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PH PF00169.29 PRP86674.1 - 1.8e-13 50.9 0.0 5.7e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 PH domain C1_1 PF00130.22 PRP86674.1 - 1.2e-09 37.9 5.0 2.1e-09 37.1 5.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PI3K_rbd PF00794.18 PRP86674.1 - 3.1e-05 24.1 0.1 9.9e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain PH_11 PF15413.6 PRP86674.1 - 0.0023 18.4 0.3 0.013 15.9 0.3 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain C1_2 PF03107.16 PRP86674.1 - 0.0074 16.6 5.1 0.015 15.6 5.1 1.5 1 0 0 1 1 1 1 C1 domain DUF4135 PF13575.6 PRP86674.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PH_8 PF15409.6 PRP86674.1 - 0.08 13.2 0.0 15 6.0 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain FYVE_2 PF02318.16 PRP86674.1 - 0.59 10.4 2.7 1.3 9.2 2.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger PHD PF00628.29 PRP86674.1 - 2.8 7.9 6.7 6.3 6.8 6.7 1.6 1 0 0 1 1 1 0 PHD-finger Ank_4 PF13637.6 PRP86675.1 - 3.8e-13 49.6 0.1 1.2e-07 32.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86675.1 - 5.7e-10 39.6 0.0 6.7e-09 36.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP86675.1 - 1.4e-07 31.7 0.0 4.7e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP86675.1 - 2.7e-07 30.7 0.0 3.2e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 PRP86675.1 - 7e-07 29.1 0.0 0.0002 21.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat ADH_zinc_N_2 PF13602.6 PRP86676.1 - 0.00077 20.5 0.0 0.0014 19.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PRP86676.1 - 0.0036 17.3 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP86676.1 - 0.009 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase_Tyr PF07714.17 PRP86677.1 - 2.5e-78 262.9 0.0 3.5e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86677.1 - 1.4e-49 168.9 0.0 2.1e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP86677.1 - 1.1e-31 108.4 77.6 2.6e-06 27.1 7.0 12.6 4 3 9 13 13 13 12 Leucine rich repeat LRR_4 PF12799.7 PRP86677.1 - 1.7e-30 104.5 78.6 2.7e-05 24.4 1.2 14.5 8 3 8 17 17 17 12 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP86677.1 - 0.0014 18.1 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_1 PF00560.33 PRP86677.1 - 0.018 15.5 68.2 3.5 8.5 0.2 19.3 20 4 0 20 20 19 0 Leucine Rich Repeat LRR_6 PF13516.6 PRP86677.1 - 0.021 14.9 57.8 5.6 7.3 0.6 15.9 17 0 0 17 17 17 0 Leucine Rich repeat Haspin_kinase PF12330.8 PRP86677.1 - 0.026 13.5 0.1 0.23 10.4 0.1 2.2 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PRP86677.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP86677.1 - 0.072 11.9 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_9 PF14580.6 PRP86677.1 - 0.24 10.9 11.9 5.4 6.5 0.2 4.9 3 1 1 4 4 4 0 Leucine-rich repeat Bac_rhodopsin PF01036.18 PRP86678.1 - 2e-40 138.8 18.7 2.7e-40 138.3 18.7 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Tmemb_170 PF10190.9 PRP86678.1 - 0.035 14.5 3.1 0.035 14.5 3.1 2.4 2 0 0 2 2 2 0 Putative transmembrane protein 170 TPR_16 PF13432.6 PRP86680.1 - 0.027 15.1 1.7 0.043 14.5 0.7 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP86680.1 - 0.027 14.7 0.1 0.24 11.7 0.0 2.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CorA PF01544.18 PRP86680.1 - 0.059 12.7 0.6 0.12 11.7 0.6 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein TPR_2 PF07719.17 PRP86680.1 - 0.11 12.6 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP86680.1 - 0.14 12.4 0.0 10 6.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PRP86680.1 - 0.33 11.9 1.9 1.1 10.3 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PIH1_CS PF18201.1 PRP86681.1 - 2e-08 34.5 0.0 2.8e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain YbaB_DNA_bd PF02575.16 PRP86684.1 - 0.24 11.7 0.1 16 5.8 0.0 2.3 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family LAMTOR PF15454.6 PRP86687.1 - 0.00079 20.0 0.2 0.0022 18.6 0.2 1.8 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Profilin PF00235.19 PRP86688.1 - 1.9e-48 163.9 0.3 2.4e-48 163.6 0.3 1.1 1 0 0 1 1 1 1 Profilin His_Phos_1 PF00300.22 PRP86689.1 - 3.2e-41 141.2 0.0 8.3e-41 139.8 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Shikimate_DH PF01488.20 PRP86689.1 - 0.0091 16.1 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ank_4 PF13637.6 PRP86690.1 - 1.5e-32 111.6 5.3 2.9e-12 46.8 0.2 4.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86690.1 - 7.8e-31 106.5 2.6 4e-14 53.0 0.6 4.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP86690.1 - 2.5e-29 101.0 7.6 1.2e-09 38.2 0.6 5.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP86690.1 - 5.1e-24 83.6 9.3 4.3e-06 26.9 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 PRP86690.1 - 6.5e-23 78.3 4.7 0.0002 21.5 0.0 6.4 7 0 0 7 7 7 5 Ankyrin repeat SLD5_C PF16922.5 PRP86691.1 - 0.03 14.5 0.1 0.073 13.3 0.1 1.6 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus PAN_4 PF14295.6 PRP86693.1 - 3.4e-14 52.5 27.3 7.1e-10 38.6 6.0 3.0 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 PRP86693.1 - 3.8e-09 36.4 5.5 0.0003 20.7 1.3 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PRP86693.1 - 3.7e-06 26.9 12.1 0.0034 17.5 1.6 2.7 2 0 0 2 2 2 2 PAN-like domain PAN_3 PF08277.12 PRP86693.1 - 7.5 6.5 14.3 1.2 9.0 3.3 2.7 2 0 0 2 2 2 0 PAN-like domain Ank_2 PF12796.7 PRP86694.1 - 1.4e-36 124.9 0.0 4.4e-09 36.8 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP86694.1 - 8.9e-24 83.6 2.8 0.0052 17.3 0.0 7.8 4 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 PRP86694.1 - 3.2e-20 71.6 4.0 0.0034 17.8 0.0 9.5 9 1 1 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 PRP86694.1 - 6.9e-16 58.1 3.2 6.4e-05 23.2 0.0 6.9 3 3 4 7 7 7 4 Ankyrin repeats (many copies) AMPK1_CBM PF16561.5 PRP86694.1 - 1.1e-13 51.2 0.1 3.3e-13 49.6 0.1 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Ank_3 PF13606.6 PRP86694.1 - 1.9e-13 49.2 0.1 3.4 8.5 0.0 9.4 10 0 0 10 10 10 3 Ankyrin repeat Adhesin_P1 PF03257.13 PRP86694.1 - 0.089 13.3 0.4 0.53 10.8 0.2 2.3 2 0 0 2 2 2 0 Mycoplasma adhesin P1 Pyr_redox_2 PF07992.14 PRP86696.1 - 6.1e-07 29.0 0.2 2.9e-06 26.7 0.1 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP86696.1 - 3.8e-05 23.7 0.7 0.088 12.8 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 PRP86696.1 - 0.0081 15.2 0.2 0.17 10.9 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 PRP86696.1 - 0.023 14.0 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP86696.1 - 0.055 12.2 0.5 5.3 5.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 PRP86696.1 - 0.14 11.7 0.0 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Spo7 PF03907.13 PRP86697.1 - 1.7e-11 44.1 0.8 2.4e-11 43.5 0.8 1.2 1 0 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 PRP86697.1 - 0.013 15.8 0.6 0.14 12.6 0.6 2.1 1 1 0 1 1 1 0 Transmembrane protein 188 Vta1 PF04652.16 PRP86698.1 - 1.1e-35 122.8 0.1 3.3e-35 121.2 0.0 1.8 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 PRP86698.1 - 6.4e-10 38.6 1.0 6.4e-10 38.6 1.0 2.0 2 0 0 2 2 2 1 Vta1 C-terminal domain DUF2721 PF11026.8 PRP86699.1 - 0.019 14.8 1.4 0.019 14.8 1.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DHHC PF01529.20 PRP86699.1 - 2 8.5 12.3 1.6 8.8 0.9 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF4064 PF13273.6 PRP86699.1 - 9.1 6.6 14.2 0.32 11.3 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) cNMP_binding PF00027.29 PRP86700.1 - 6.6e-23 80.6 0.0 3.2e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Metallophos PF00149.28 PRP86700.1 - 7e-07 29.9 0.3 2.3e-05 25.0 0.3 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PRP86700.1 - 2.7e-06 27.7 0.2 4.1e-05 23.8 0.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PEMT PF04191.13 PRP86701.1 - 1.7e-51 173.0 9.6 1.9e-30 105.4 1.3 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase UPF0242 PF06785.11 PRP86701.1 - 0.00014 22.0 0.0 0.00035 20.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus START PF01852.19 PRP86702.1 - 4.1e-28 98.2 0.0 6e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 START domain Polyketide_cyc2 PF10604.9 PRP86702.1 - 0.032 14.5 0.0 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport IF4E PF01652.18 PRP86703.1 - 2e-56 190.2 0.2 2.4e-56 189.9 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IgG_binding_B PF01378.17 PRP86703.1 - 0.082 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 B domain SIS PF01380.22 PRP86704.1 - 6.3e-58 194.3 0.2 1.1e-33 115.9 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 PRP86704.1 - 5.3e-15 55.8 0.0 1.3e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain WWE PF02825.20 PRP86704.1 - 3.5e-12 46.7 2.9 1e-11 45.2 2.9 1.9 1 0 0 1 1 1 1 WWE domain GATase_7 PF13537.6 PRP86704.1 - 2.4e-09 37.2 0.0 5.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Linker_histone PF00538.19 PRP86704.1 - 2.1e-07 31.2 0.1 7.5e-07 29.4 0.1 2.0 1 0 0 1 1 1 1 linker histone H1 and H5 family GATase_4 PF13230.6 PRP86704.1 - 0.00022 20.2 0.0 0.00041 19.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Sigma_1s PF02454.16 PRP86704.1 - 0.026 14.5 0.0 0.098 12.6 0.0 2.0 1 0 0 1 1 1 0 Sigma 1s protein PrmA PF06325.13 PRP86705.1 - 2.4e-10 40.3 0.4 3.8e-10 39.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PRP86705.1 - 3e-10 40.7 0.0 7.5e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP86705.1 - 1.4e-07 31.5 0.1 3.1e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP86705.1 - 2.6e-07 31.2 0.0 7.5e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP86705.1 - 7.1e-06 26.0 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PRP86705.1 - 2.8e-05 23.2 0.1 6.4e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 PRP86705.1 - 4.9e-05 22.9 0.1 8.5e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 PRP86705.1 - 0.00028 21.6 0.0 0.0006 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PRP86705.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 PRP86705.1 - 0.0084 16.1 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 PRP86705.1 - 0.023 14.1 0.1 0.051 13.0 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.19 PRP86705.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 PRP86705.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 PRP86705.1 - 0.17 13.0 0.0 0.35 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain START PF01852.19 PRP86706.1 - 2.7e-35 121.7 0.2 1.8e-28 99.4 0.0 2.5 3 0 0 3 3 3 2 START domain Polyketide_cyc2 PF10604.9 PRP86706.1 - 0.089 13.1 0.0 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DAD PF02109.16 PRP86707.1 - 7.5e-37 126.0 1.8 1.7e-36 124.8 1.8 1.6 1 0 0 1 1 1 1 DAD family DUF1681 PF07933.14 PRP86708.1 - 2.9e-52 176.3 1.1 3.9e-51 172.7 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1681) TFIIA PF03153.13 PRP86708.1 - 2.3 8.1 27.2 3.2 7.7 27.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit R3H-assoc PF13902.6 PRP86709.1 - 1.3e-10 41.8 0.3 2.3e-10 41.0 0.3 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain Pkinase_Tyr PF07714.17 PRP86710.1 - 1.5e-69 234.2 0.0 2.7e-69 233.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86710.1 - 1e-50 172.5 0.0 2e-50 171.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP86710.1 - 6.5e-41 137.9 59.8 4.3e-08 32.8 4.1 13.1 8 3 3 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 PRP86710.1 - 7.5e-39 131.1 69.5 3.1e-05 24.3 0.8 16.2 10 4 8 18 18 18 12 Leucine Rich repeats (2 copies) SIR2 PF02146.17 PRP86710.1 - 4.9e-23 82.0 1.7 4.9e-17 62.4 0.0 2.9 2 1 1 3 3 3 2 Sir2 family LRR_1 PF00560.33 PRP86710.1 - 1.2e-12 46.5 46.9 4.2 8.3 0.0 20.4 24 0 0 24 24 22 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP86710.1 - 2.2e-06 27.2 55.4 8.4 6.7 0.0 16.5 17 0 0 17 17 17 2 Leucine Rich repeat CAP_C PF08603.11 PRP86710.1 - 0.00022 20.9 5.0 0.00065 19.4 5.0 1.8 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Kdo PF06293.14 PRP86710.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Wzy_C PF04932.15 PRP86710.1 - 0.054 13.1 1.0 7.1 6.2 0.2 2.5 2 0 0 2 2 2 0 O-Antigen ligase DSPc PF00782.20 PRP86710.1 - 0.089 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2207 PF09972.9 PRP86710.1 - 0.093 11.5 0.0 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Pkinase_fungal PF17667.1 PRP86710.1 - 0.12 11.2 0.0 0.46 9.2 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase YajC PF02699.15 PRP86710.1 - 0.17 11.8 0.2 0.43 10.5 0.2 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit EphA2_TM PF14575.6 PRP86710.1 - 0.22 12.4 0.9 0.68 10.8 0.2 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 PRP86710.1 - 6.5 6.3 12.1 0.025 14.0 2.2 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PAP_assoc PF03828.19 PRP86711.1 - 2.9e-10 40.2 0.0 2.9e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PRP86711.1 - 0.00013 22.2 0.7 0.00031 21.0 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain OAS1_C PF10421.9 PRP86711.1 - 0.027 14.0 0.0 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Polbeta PF18765.1 PRP86711.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase AP3D1 PF06375.11 PRP86711.1 - 0.44 10.8 17.2 0.031 14.5 2.6 2.8 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 SPT6_acidic PF14632.6 PRP86711.1 - 1.9 9.1 17.0 2.3 8.9 4.2 2.7 2 0 0 2 2 2 0 Acidic N-terminal SPT6 AAA_6 PF12774.7 PRP86712.1 - 1.5e-157 523.7 1.8 1.3e-155 517.4 0.0 3.9 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 PRP86712.1 - 9.1e-154 513.2 3.6 9.1e-154 513.2 3.6 4.9 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PRP86712.1 - 2.8e-133 444.9 12.1 2.8e-133 444.9 12.1 5.3 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PRP86712.1 - 3.4e-102 341.2 8.4 2.9e-101 338.2 0.0 3.9 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PRP86712.1 - 5.4e-99 331.3 0.0 5.4e-99 331.3 0.0 3.9 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 PRP86712.1 - 4.1e-85 283.8 2.8 3.5e-79 264.5 0.0 4.2 3 1 0 3 3 3 2 P-loop containing dynein motor region AAA_9 PF12781.7 PRP86712.1 - 2.1e-84 282.1 7.4 6.5e-83 277.2 2.3 4.1 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 PRP86712.1 - 3.3e-60 202.6 0.7 1.1e-59 200.9 0.7 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PRP86712.1 - 4.8e-56 190.2 15.4 9.8e-56 189.2 15.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PRP86712.1 - 2.9e-43 146.7 0.0 4.6e-40 136.4 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 PRP86712.1 - 7.7e-38 129.6 0.0 8.1e-16 58.3 0.0 5.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 PRP86712.1 - 6.8e-32 110.3 0.3 3e-31 108.2 0.3 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PRP86712.1 - 4.1e-24 84.7 1.8 4.9e-22 78.0 0.1 3.2 2 0 0 2 2 2 1 AAA+ lid domain DUF829 PF05705.14 PRP86712.1 - 1.6e-16 61.0 1.8 2.9e-15 56.8 1.6 3.1 2 1 0 2 2 1 1 Eukaryotic protein of unknown function (DUF829) AAA PF00004.29 PRP86712.1 - 3e-12 47.1 1.3 0.0006 20.3 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP86712.1 - 4.6e-12 46.4 0.9 2.8e-05 24.4 0.0 5.5 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 PRP86712.1 - 3.5e-09 37.3 4.6 0.0074 16.7 0.0 6.1 5 0 0 5 5 4 2 AAA ATPase domain DUF815 PF05673.13 PRP86712.1 - 1.2e-07 31.1 0.7 0.00044 19.5 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 PRP86712.1 - 2.4e-07 31.4 2.8 0.002 18.6 0.1 4.4 3 0 0 3 3 2 2 ABC transporter AAA_18 PF13238.6 PRP86712.1 - 7.9e-07 29.7 0.4 1 9.9 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 PRP86712.1 - 1.2e-06 28.4 4.7 0.042 13.6 0.1 3.9 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 PRP86712.1 - 9.6e-06 25.4 1.5 0.037 13.7 0.1 3.8 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_19 PF13245.6 PRP86712.1 - 1.6e-05 25.3 2.2 0.052 13.9 0.0 4.0 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 PRP86712.1 - 4e-05 22.8 5.4 0.17 10.9 0.2 3.8 4 0 0 4 4 3 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PRP86712.1 - 5.8e-05 23.1 0.3 0.43 10.5 0.0 3.8 3 0 0 3 3 3 2 RsgA GTPase Mg_chelatase PF01078.21 PRP86712.1 - 9.9e-05 21.8 1.2 0.3 10.4 0.0 3.6 5 0 0 5 5 3 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PRP86712.1 - 0.0001 22.7 0.2 6.5 7.2 0.0 4.9 4 0 0 4 4 4 0 RNA helicase Roc PF08477.13 PRP86712.1 - 0.0001 22.5 2.0 0.015 15.5 0.2 3.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 PRP86712.1 - 0.00026 20.3 0.1 0.34 10.2 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin DEAD PF00270.29 PRP86712.1 - 0.00027 20.8 0.0 0.6 9.9 0.0 3.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 PRP86712.1 - 0.00032 20.7 0.9 0.1 12.6 0.1 3.7 3 0 0 3 3 3 1 AAA domain TrwB_AAD_bind PF10412.9 PRP86712.1 - 0.00036 19.5 0.5 0.24 10.3 0.2 2.8 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 PRP86712.1 - 0.001 19.2 0.8 7.8 6.7 0.0 4.7 5 0 0 5 5 3 0 AAA domain DUF87 PF01935.17 PRP86712.1 - 0.0014 18.8 0.1 0.0014 18.8 0.1 5.4 6 0 0 6 6 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 PRP86712.1 - 0.0017 17.7 6.5 0.21 10.9 0.0 4.0 5 0 0 5 5 4 2 FtsK/SpoIIIE family AAA_29 PF13555.6 PRP86712.1 - 0.0052 16.5 2.5 3.1 7.6 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 PRP86712.1 - 0.0067 16.2 1.7 2.8 7.7 0.3 3.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 PRP86712.1 - 0.018 15.0 4.5 0.16 11.9 0.1 3.5 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 PRP86712.1 - 0.022 14.5 0.9 19 4.9 0.1 3.9 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 PRP86712.1 - 0.025 13.9 1.9 0.66 9.3 0.2 3.1 2 0 0 2 2 2 0 AIG1 family AAA_2 PF07724.14 PRP86712.1 - 0.031 14.4 0.3 1.2 9.2 0.1 3.4 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) TniB PF05621.11 PRP86712.1 - 0.05 13.0 0.2 4.7 6.6 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein DUF853 PF05872.12 PRP86712.1 - 0.05 12.2 3.0 5.5 5.5 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) NACHT PF05729.12 PRP86712.1 - 0.051 13.5 1.2 13 5.7 0.0 3.8 4 0 0 4 4 3 0 NACHT domain PRK PF00485.18 PRP86712.1 - 0.069 12.9 0.5 3 7.5 0.0 3.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 PRP86712.1 - 0.08 13.0 1.2 13 5.9 0.1 3.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase TsaE PF02367.17 PRP86712.1 - 0.083 12.9 8.1 0.29 11.2 0.2 4.2 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 PRP86712.1 - 0.12 12.0 0.1 0.32 10.6 0.1 1.7 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 PRP86712.1 - 1.6 8.3 8.0 5.5 6.6 0.1 3.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Gtr1_RagA PF04670.12 PRP86712.1 - 9.6 5.5 11.8 0.19 11.0 0.1 3.3 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region Kinesin PF00225.23 PRP86713.1 - 6.2e-100 334.4 0.8 6.2e-100 334.4 0.8 2.1 2 0 0 2 2 2 1 Kinesin motor domain Gelsolin PF00626.22 PRP86713.1 - 6.1e-43 144.6 2.5 3e-09 36.7 0.0 6.4 6 0 0 6 6 6 5 Gelsolin repeat Microtub_bd PF16796.5 PRP86713.1 - 1.2e-39 135.7 0.0 1.2e-39 135.7 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding RhoGAP PF00620.27 PRP86713.1 - 7.7e-17 61.5 0.2 1e-14 54.6 0.2 2.9 1 1 0 1 1 1 1 RhoGAP domain VHP PF02209.19 PRP86713.1 - 5.7e-11 42.3 3.3 1.9e-10 40.6 3.3 2.0 1 0 0 1 1 1 1 Villin headpiece domain ATG16 PF08614.11 PRP86713.1 - 0.0039 17.4 47.4 0.0062 16.8 20.1 3.2 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) DMPK_coil PF08826.10 PRP86713.1 - 0.0094 16.0 9.8 0.0094 16.0 9.8 4.2 3 1 1 5 5 5 1 DMPK coiled coil domain like Ribosomal_60s PF00428.19 PRP86714.1 - 0.34 11.5 5.2 0.68 10.6 5.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein dCMP_cyt_deam_1 PF00383.23 PRP86715.1 - 4e-21 74.8 0.5 5.9e-21 74.2 0.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PRP86715.1 - 5.9e-17 61.7 0.2 8.2e-17 61.2 0.2 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 PRP86715.1 - 0.00013 22.0 0.4 0.00032 20.8 0.4 1.6 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 PRP86715.1 - 0.003 17.7 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 PRP86715.1 - 0.0051 16.9 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 Inv-AAD PF18785.1 PRP86715.1 - 0.013 15.4 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase Destabilase PF05497.12 PRP86715.1 - 0.033 14.5 0.1 0.05 13.9 0.1 1.2 1 0 0 1 1 1 0 Destabilase APOBEC2 PF18772.1 PRP86715.1 - 0.048 13.7 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 Ogr_Delta PF04606.12 PRP86715.1 - 0.06 13.3 0.1 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 Ogr/Delta-like zinc finger NAD1 PF18778.1 PRP86715.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 AID PF18767.1 PRP86715.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Activation induced deaminase Alpha-amylase PF00128.24 PRP86716.1 - 7.9e-104 347.8 0.7 6.3e-103 344.9 0.7 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 PRP86716.1 - 2.1e-07 31.0 0.0 4.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Acetyltransf_1 PF00583.25 PRP86716.1 - 0.00092 19.4 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3459 PF11941.8 PRP86716.1 - 0.0041 17.4 0.0 0.0098 16.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.18 PRP86716.1 - 0.0059 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Acetyltransf_CG PF14542.6 PRP86716.1 - 0.015 15.4 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 PRP86716.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein hDGE_amylase PF14701.6 PRP86716.1 - 0.043 12.9 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Acetyltransf_9 PF13527.7 PRP86716.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP86716.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Cyc-maltodext_C PF10438.9 PRP86716.1 - 0.15 12.1 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Phytochelatin PF05023.14 PRP86717.1 - 1.3e-88 295.8 0.0 2.4e-88 294.9 0.0 1.5 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 PRP86717.1 - 0.046 14.3 0.0 0.37 11.3 0.0 2.3 1 1 0 1 1 1 0 Peptidase_C39 like family EF-hand_7 PF13499.6 PRP86718.1 - 3.1e-07 30.7 1.0 4.2e-07 30.3 1.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PRP86718.1 - 5.1e-06 26.0 1.4 0.0022 17.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PRP86718.1 - 2.2e-05 23.7 1.1 0.00027 20.3 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PRP86718.1 - 4.9e-05 23.1 2.1 0.17 11.7 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF_assoc_1 PF08355.12 PRP86718.1 - 0.0035 16.9 0.1 0.0047 16.5 0.1 1.2 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 PRP86718.1 - 0.0041 17.1 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 EF hand associated Caleosin PF05042.13 PRP86718.1 - 0.011 15.7 0.9 0.17 11.8 0.1 2.1 1 1 1 2 2 2 0 Caleosin related protein EF-hand_5 PF13202.6 PRP86718.1 - 0.12 11.9 0.6 0.12 11.9 0.6 1.9 2 0 0 2 2 2 0 EF hand DUF3976 PF13121.6 PRP86718.1 - 0.5 10.5 1.0 1 9.6 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3976) LAG1-DNAbind PF09271.11 PRP86720.1 - 0.06 14.0 0.8 0.28 11.8 0.3 2.4 2 1 0 2 2 2 0 LAG1, DNA binding WD40 PF00400.32 PRP86721.1 - 2.4e-16 59.8 29.1 0.00014 22.6 0.1 9.8 9 2 1 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP86721.1 - 1e-14 54.6 1.6 6.4e-05 23.2 0.2 6.5 4 2 3 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP86721.1 - 0.031 13.2 0.0 3.6 6.5 0.0 3.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PRP86721.1 - 0.039 13.9 0.0 1.8 8.6 0.1 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MIIP PF15734.5 PRP86721.1 - 0.23 10.9 0.1 0.41 10.1 0.1 1.3 1 0 0 1 1 1 0 Migration and invasion-inhibitory ResIII PF04851.15 PRP86722.1 - 3.8e-07 30.3 0.2 2.7e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 PRP86722.1 - 3e-05 22.9 0.0 0.00017 20.5 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_19 PF13245.6 PRP86722.1 - 0.039 14.3 0.0 0.59 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PRP86722.1 - 0.065 13.7 0.0 0.35 11.3 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CVNH PF08881.10 PRP86722.1 - 0.072 13.8 0.0 0.072 13.8 0.0 2.5 3 0 0 3 3 3 0 CVNH domain Pro-kuma_activ PF09286.11 PRP86723.1 - 4.4e-23 82.1 0.0 9.6e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain MMR_HSR1 PF01926.23 PRP86723.1 - 3.8e-11 43.1 0.1 1.4e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP86723.1 - 1.5e-10 41.3 0.0 3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 PRP86723.1 - 0.0024 17.4 0.2 0.0087 15.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PRP86723.1 - 0.017 14.7 0.5 4.4 6.8 0.0 2.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP86723.1 - 0.023 14.1 0.2 0.49 9.7 0.0 2.6 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Roc PF08477.13 PRP86723.1 - 0.035 14.3 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Peptidase_S8 PF00082.22 PRP86723.1 - 0.042 13.1 0.6 0.13 11.5 0.6 1.8 1 0 0 1 1 1 0 Subtilase family TrwB_AAD_bind PF10412.9 PRP86723.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ABC_tran PF00005.27 PRP86723.1 - 0.14 12.7 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 PRP86723.1 - 0.14 11.6 0.1 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family TniB PF05621.11 PRP86723.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 PRP86723.1 - 1.1 9.3 5.2 0.24 11.4 0.1 2.5 2 1 1 3 3 3 0 Dynamin family An_peroxidase PF03098.15 PRP86724.1 - 2.4e-135 452.1 0.0 2.9e-135 451.9 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase PKD_3 PF16820.5 PRP86724.1 - 0.095 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 PKD-like domain Methyltransf_32 PF13679.6 PRP86725.1 - 5.2e-23 81.8 0.0 1.1e-22 80.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 PRP86725.1 - 0.00017 21.2 1.2 0.063 12.8 0.3 2.8 2 1 0 2 2 2 2 Methyltransferase TRM13 Methyltransf_23 PF13489.6 PRP86725.1 - 0.0014 18.5 0.0 0.0051 16.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP86725.1 - 0.05 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 PRP86725.1 - 0.18 11.5 0.1 0.41 10.4 0.1 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 PRP86725.1 - 0.2 11.2 0.1 0.58 9.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Pkinase PF00069.25 PRP86726.1 - 1.4e-59 201.6 0.0 8.6e-37 126.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86726.1 - 5.3e-26 91.5 0.1 2.5e-18 66.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.24 PRP86726.1 - 3.7e-10 39.8 0.0 9.3e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 PX domain Haspin_kinase PF12330.8 PRP86726.1 - 9.8e-07 28.0 0.1 1.8e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain SH3_9 PF14604.6 PRP86726.1 - 2.2e-06 27.4 0.1 0.00014 21.7 0.0 3.0 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 PRP86726.1 - 8.9e-06 25.2 0.1 0.0014 18.2 0.0 3.3 3 0 0 3 3 3 1 SH3 domain Kinase-like PF14531.6 PRP86726.1 - 2e-05 24.1 0.3 9.9e-05 21.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SH3_2 PF07653.17 PRP86726.1 - 0.00089 18.9 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain APH PF01636.23 PRP86726.1 - 0.0039 17.1 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP86726.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PRP86726.1 - 0.11 11.6 0.0 0.55 9.2 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 TIG PF01833.24 PRP86727.1 - 4.1e-10 39.6 8.0 1.3e-07 31.5 0.3 3.4 5 0 0 5 5 5 2 IPT/TIG domain CarboxypepD_reg PF13620.6 PRP86727.1 - 2.7e-08 33.9 0.0 8.4e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PRP86727.1 - 0.00011 22.1 0.0 0.00038 20.4 0.0 1.9 2 0 0 2 2 2 1 CarboxypepD_reg-like domain zf-MYND PF01753.18 PRP86728.1 - 9.7e-06 25.6 14.7 3.3e-05 23.9 14.7 2.0 1 0 0 1 1 1 1 MYND finger NuDC PF16273.5 PRP86728.1 - 0.04 14.4 2.1 0.13 12.8 2.1 1.8 1 0 0 1 1 1 0 Nuclear distribution C domain SPRY PF00622.28 PRP86729.1 - 8.8e-16 58.1 0.1 1.5e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Metallophos PF00149.28 PRP86731.1 - 2e-36 126.4 0.2 3.1e-36 125.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PRP86731.1 - 1e-05 25.9 0.5 2.9e-05 24.4 0.5 1.8 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 PRP86731.1 - 0.091 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 PRP86731.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Iso_dh PF00180.20 PRP86732.1 - 1.9e-92 310.1 0.1 2.3e-92 309.8 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Dynamin_N PF00350.23 PRP86734.1 - 3.9e-11 43.3 0.0 2e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PRP86734.1 - 0.00019 21.5 0.0 0.00073 19.6 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase WH2 PF02205.20 PRP86734.1 - 0.014 15.2 0.1 0.014 15.2 0.1 2.3 2 0 0 2 2 2 0 WH2 motif Arf PF00025.21 PRP86734.1 - 0.025 14.1 0.1 0.2 11.1 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family BLYB PF05289.11 PRP86734.1 - 0.047 13.9 1.5 14 5.9 0.5 3.3 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein DNTTIP1_dimer PF18192.1 PRP86734.1 - 0.11 12.9 0.1 4.2 7.8 0.1 2.9 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain Mer2 PF09074.10 PRP86734.1 - 0.15 11.9 4.1 2.3 8.0 3.7 2.4 1 1 1 2 2 2 0 Mer2 YibE_F PF07907.11 PRP86736.1 - 0.039 13.5 3.2 0.063 12.8 3.2 1.2 1 0 0 1 1 1 0 YibE/F-like protein HAD_2 PF13419.6 PRP86737.1 - 5.3e-17 62.5 0.0 6.8e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP86737.1 - 1.2e-11 45.3 0.0 3.7e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP86737.1 - 1.2e-05 25.3 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 PRP86737.1 - 0.015 15.1 0.2 0.025 14.3 0.2 1.5 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Acid_PPase PF12689.7 PRP86737.1 - 0.05 13.5 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Acid Phosphatase Chordopox_A15 PF05846.12 PRP86737.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A15 protein PWI PF01480.17 PRP86739.1 - 1.2e-21 76.7 0.2 2.5e-21 75.8 0.2 1.5 1 0 0 1 1 1 1 PWI domain MerR-DNA-bind PF09278.11 PRP86739.1 - 0.087 13.4 0.5 0.087 13.4 0.5 1.9 2 0 0 2 2 2 0 MerR, DNA binding CpXC PF14353.6 PRP86739.1 - 0.11 12.5 0.6 0.27 11.3 0.1 1.8 2 0 0 2 2 2 0 CpXC protein Hid1 PF12722.7 PRP86739.1 - 0.61 8.1 11.6 0.79 7.8 11.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.9 PRP86739.1 - 3.6 6.0 16.0 4.9 5.6 16.0 1.2 1 0 0 1 1 1 0 Macoilin family Smr PF01713.21 PRP86740.1 - 8.1e-14 51.8 0.6 2.1e-13 50.4 0.6 1.8 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 PRP86740.1 - 2.6e-10 40.5 6.3 2.6e-10 40.5 6.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.16 PRP86740.1 - 1.3e-08 34.4 2.2 0.0016 18.1 0.1 2.9 3 0 0 3 3 3 2 CUE domain Pkinase PF00069.25 PRP86741.1 - 3.4e-60 203.7 0.3 5.6e-60 202.9 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86741.1 - 8.5e-23 80.9 1.4 2.3e-22 79.5 1.4 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP86741.1 - 1.2e-08 34.6 0.3 2.8e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH PF00169.29 PRP86741.1 - 2e-06 28.3 1.2 0.00019 21.9 0.0 3.0 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 PRP86741.1 - 0.00095 18.0 0.0 0.0023 16.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 PRP86741.1 - 0.038 13.5 0.1 0.1 12.1 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 PRP86741.1 - 0.062 13.2 0.0 0.49 10.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PEX11 PF05648.14 PRP86743.1 - 2.8 7.3 5.2 1 8.8 0.1 2.6 3 1 1 4 4 4 0 Peroxisomal biogenesis factor 11 (PEX11) V-ATPase_H_N PF03224.14 PRP86744.1 - 0.011 15.0 8.2 0.65 9.2 0.0 3.8 1 1 1 2 2 2 0 V-ATPase subunit H PB1 PF00564.24 PRP86744.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 PB1 domain Arm PF00514.23 PRP86744.1 - 0.4 10.8 7.6 86 3.4 0.2 6.5 5 2 2 7 7 7 0 Armadillo/beta-catenin-like repeat RRM_1 PF00076.22 PRP86746.1 - 2.5e-42 142.5 1.2 3e-12 46.2 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PRP86746.1 - 1e-06 28.7 0.9 0.091 12.8 0.0 4.0 4 0 0 4 4 4 2 RNA binding motif RRM_5 PF13893.6 PRP86746.1 - 3.7e-05 23.3 0.0 0.4 10.3 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IL7 PF01415.16 PRP86746.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin 7/9 family UPF0184 PF03670.13 PRP86747.1 - 0.0011 19.3 0.6 0.002 18.5 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) Mei5_like PF17021.5 PRP86747.1 - 0.059 13.4 0.5 0.094 12.8 0.5 1.5 1 1 0 1 1 1 0 Putative double-strand recombination repair-like DUF4866 PF16160.5 PRP86747.1 - 0.067 12.5 0.0 0.094 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4866) WD40 PF00400.32 PRP86748.1 - 2.3e-35 120.0 29.0 9e-07 29.5 0.5 12.2 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP86748.1 - 4.5e-13 49.3 0.0 0.02 15.2 0.0 6.6 4 2 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP86748.1 - 0.00071 18.6 0.0 0.58 9.1 0.0 4.1 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP86748.1 - 0.0073 16.2 0.3 0.26 11.1 0.1 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HELP PF03451.14 PRP86748.1 - 0.01 15.7 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 HELP motif Peroxidase_2 PF01328.17 PRP86749.1 - 3.8e-106 353.6 0.0 1.1e-51 176.1 0.0 2.1 2 0 0 2 2 2 2 Peroxidase, family 2 DUF3498 PF12004.8 PRP86749.1 - 0.0035 16.6 2.0 0.95 8.6 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3498) SM-ATX PF14438.6 PRP86749.1 - 0.082 13.1 0.1 10 6.3 0.0 2.6 2 0 0 2 2 2 0 Ataxin 2 SM domain FAA_hydro_N_2 PF18288.1 PRP86749.1 - 0.098 13.1 0.0 5.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Na_H_antiport_1 PF06965.12 PRP86749.1 - 0.13 11.1 0.0 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Na+/H+ antiporter 1 FliL PF03748.14 PRP86750.1 - 0.14 12.7 0.1 0.32 11.6 0.1 1.5 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Ribosomal_S10 PF00338.22 PRP86753.1 - 1.2e-28 99.2 0.3 1.4e-28 98.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1084 PF06454.11 PRP86754.1 - 5.3e-23 81.8 15.6 7.1e-23 81.4 15.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Tlr3_TMD PF17968.1 PRP86754.1 - 1.5 9.1 9.3 5.8 7.2 0.8 3.8 3 0 0 3 3 3 0 Toll-like receptor 3 trans-membrane domain Lon_C PF05362.13 PRP86756.1 - 2.6e-64 216.5 0.0 1.8e-63 213.8 0.0 2.2 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 PRP86756.1 - 7.5e-20 71.7 0.0 2.2e-19 70.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 PRP86756.1 - 1.6e-19 70.6 0.2 6.2e-19 68.7 0.1 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain C2 PF00168.30 PRP86756.1 - 4e-15 56.0 0.0 2.8e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 C2 domain AAA_5 PF07728.14 PRP86756.1 - 1.7e-06 28.1 0.0 3.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PRP86756.1 - 4.7e-06 26.8 0.0 9.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 PRP86756.1 - 4.7e-06 26.5 0.0 1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 PRP86756.1 - 1.7e-05 23.9 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 PRP86756.1 - 0.0025 17.6 0.0 0.011 15.4 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PRP86756.1 - 0.0025 18.1 2.2 0.06 13.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP86756.1 - 0.0044 17.4 0.6 0.021 15.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 PRP86756.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 PRP86756.1 - 0.026 13.7 1.4 0.26 10.4 0.1 2.9 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_18 PF13238.6 PRP86756.1 - 0.035 14.6 0.1 0.23 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PRP86756.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_3 PF07726.11 PRP86756.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.14 PRP86757.1 - 4.6e-30 104.8 0.0 1.5e-29 103.1 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PQ-loop PF04193.14 PRP86758.1 - 1.7e-37 127.0 9.7 1.4e-18 66.4 0.7 2.6 2 0 0 2 2 2 2 PQ loop repeat HrcA_DNA-bdg PF03444.15 PRP86758.1 - 0.16 11.6 0.1 0.34 10.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding ABC_membrane PF00664.23 PRP86759.1 - 1.6e-53 182.1 12.3 3e-53 181.3 12.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PRP86759.1 - 1.9e-36 125.6 0.0 4.1e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter PAN_4 PF14295.6 PRP86759.1 - 2.5e-07 30.5 1.3 6e-07 29.3 1.3 1.6 1 0 0 1 1 1 1 PAN domain NMT1 PF09084.11 PRP86759.1 - 5.5e-07 29.7 0.1 9.6e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 NMT1/THI5 like SMC_N PF02463.19 PRP86759.1 - 2.2e-05 24.0 0.5 0.0035 16.8 0.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain PAN_1 PF00024.26 PRP86759.1 - 7.9e-05 22.5 0.9 0.0002 21.3 0.9 1.6 1 0 0 1 1 1 1 PAN domain AAA_22 PF13401.6 PRP86759.1 - 0.00082 19.7 0.0 0.0053 17.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PRP86759.1 - 0.0018 18.1 0.1 0.0057 16.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP86759.1 - 0.0043 17.5 0.2 0.012 16.0 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain NMT1_3 PF16868.5 PRP86759.1 - 0.0057 16.1 0.2 0.024 14.1 0.1 2.0 2 0 0 2 2 2 1 NMT1-like family AAA_29 PF13555.6 PRP86759.1 - 0.013 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 PRP86759.1 - 0.021 14.4 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PRP86759.1 - 0.028 14.3 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 PRP86759.1 - 0.035 13.8 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.29 PRP86759.1 - 0.07 12.9 0.2 0.83 9.4 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_18 PF13238.6 PRP86759.1 - 0.19 12.3 0.0 0.51 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain PAN_2 PF08276.11 PRP86759.1 - 0.34 11.1 2.5 0.83 9.8 2.5 1.6 1 0 0 1 1 1 0 PAN-like domain DUF2052 PF09747.9 PRP86760.1 - 7e-32 111.2 30.1 8.9e-32 110.8 27.0 2.4 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Ephrin_rec_like PF07699.13 PRP86762.1 - 3.4e-21 74.7 147.6 2.6e-05 23.9 4.2 13.8 4 1 11 15 15 15 12 Putative ephrin-receptor like NCD3G PF07562.14 PRP86762.1 - 9.1e-05 22.4 96.4 0.022 14.7 6.7 11.4 9 1 2 11 11 11 9 Nine Cysteines Domain of family 3 GPCR DUF2244 PF10003.9 PRP86762.1 - 6.8 6.4 6.0 0.42 10.3 0.1 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) FMN_red PF03358.15 PRP86763.1 - 2.6e-09 37.0 0.0 2.6e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 PRP86763.1 - 7e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 PRP86763.1 - 7.2e-06 26.3 0.2 0.00087 19.5 0.2 2.3 1 1 0 1 1 1 1 Flavodoxin GGDEF PF00990.21 PRP86763.1 - 0.0055 16.5 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Diguanylate cyclase, GGDEF domain Flavodoxin_5 PF12724.7 PRP86763.1 - 0.089 13.0 0.0 16 5.7 0.0 2.4 1 1 1 2 2 2 0 Flavodoxin domain HATPase_c PF02518.26 PRP86764.1 - 6.4e-42 142.6 1.0 9.3e-21 74.4 0.1 2.9 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP86764.1 - 9.3e-21 73.6 3.4 9.3e-09 35.2 0.0 4.0 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 PRP86764.1 - 2e-19 69.8 0.3 1.6e-15 57.3 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c_3 PF13589.6 PRP86764.1 - 2.1e-05 24.4 0.0 0.007 16.2 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 PRP86764.1 - 4.6e-05 23.4 0.1 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 PRP86764.1 - 0.001 18.9 0.1 0.014 15.3 0.0 2.8 3 0 0 3 3 3 1 GHKL domain GAF_2 PF13185.6 PRP86764.1 - 0.0072 16.6 0.0 1.1 9.5 0.0 2.7 2 0 0 2 2 2 1 GAF domain PI3_PI4_kinase PF00454.27 PRP86765.1 - 9e-35 120.7 0.1 6.3e-24 85.2 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PRP86765.1 - 6.7e-21 74.5 0.1 1.7e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) TIMELESS PF04821.14 PRP86765.1 - 0.028 13.7 0.1 0.35 10.1 0.0 2.3 2 0 0 2 2 2 0 Timeless protein PX PF00787.24 PRP86765.1 - 0.12 12.4 0.4 0.46 10.5 0.2 2.1 2 0 0 2 2 2 0 PX domain Ribosomal_L2_C PF03947.18 PRP86766.1 - 5.9e-44 149.3 3.9 1.3e-43 148.2 3.9 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PRP86766.1 - 3.7e-18 65.3 0.2 8.5e-18 64.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain ABC_tran PF00005.27 PRP86767.1 - 2.1e-29 102.8 0.0 4.3e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PRP86767.1 - 6.1e-11 42.0 30.4 5.2e-10 39.0 30.7 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 PRP86767.1 - 0.022 14.6 0.0 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PRP86767.1 - 0.022 14.5 0.1 0.043 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PRP86767.1 - 0.045 13.7 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 PRP86767.1 - 0.16 12.4 1.8 0.19 12.2 0.2 1.7 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PRP86767.1 - 0.18 11.2 0.1 0.3 10.4 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SET PF00856.28 PRP86768.1 - 1.4e-09 38.5 0.0 1.8e-08 34.9 0.0 2.4 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 PRP86768.1 - 2.2e-05 24.2 0.7 0.29 11.3 0.2 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 PRP86768.1 - 0.0061 16.6 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_12 PF13424.6 PRP86768.1 - 0.13 12.5 0.0 11 6.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP86768.1 - 1.3 9.0 5.0 12 6.0 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.21 PRP86769.1 - 7e-12 45.9 0.0 7e-12 45.9 0.0 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Transposase_28 PF04195.12 PRP86769.1 - 0.016 15.4 0.9 0.044 14.0 0.0 2.2 2 0 0 2 2 2 0 Putative gypsy type transposon Phage_holin_5_2 PF16079.5 PRP86769.1 - 0.033 14.5 3.5 1.5 9.2 0.1 3.0 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF4337 PF14235.6 PRP86769.1 - 0.39 10.8 1.3 1 9.4 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pkinase PF00069.25 PRP86770.1 - 1.2e-50 172.3 0.0 1.5e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86770.1 - 4.3e-21 75.4 0.0 8.6e-21 74.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP86770.1 - 0.0076 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2439 PF10382.9 PRP86770.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) APH PF01636.23 PRP86770.1 - 0.14 12.0 0.3 1.2 9.0 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP86770.1 - 0.15 11.4 0.2 2.1 7.6 0.1 2.7 2 1 0 2 2 2 0 Kinase-like DBP10CT PF08147.12 PRP86770.1 - 0.22 11.8 0.9 0.57 10.5 0.1 2.0 2 0 0 2 2 2 0 DBP10CT (NUC160) domain Glyco_hydro_16 PF00722.21 PRP86772.1 - 2.4e-07 30.4 3.6 0.042 13.3 0.0 3.7 2 1 1 3 3 3 2 Glycosyl hydrolases family 16 DUF4690 PF15756.5 PRP86772.1 - 0.0019 18.8 2.0 0.0019 18.8 2.0 2.0 2 0 0 2 2 2 1 Small Novel Rich in Cartilage RIFIN PF02009.16 PRP86772.1 - 0.51 10.2 2.1 0.76 9.6 2.1 1.2 1 0 0 1 1 1 0 Rifin DUF4448 PF14610.6 PRP86772.1 - 1.2 8.9 6.7 0.25 11.1 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) PAS_8 PF13188.7 PRP86773.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain Zn_clus PF00172.18 PRP86773.1 - 0.61 10.3 23.2 0.071 13.3 18.8 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC3 PF12895.7 PRP86776.1 - 0.0016 18.6 0.5 1.8 8.8 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 PRP86776.1 - 0.016 15.8 0.0 13 6.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4208 PF13907.6 PRP86776.1 - 0.71 10.3 3.2 7.3 7.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) zf-AN1 PF01428.16 PRP86777.1 - 1.1e-12 47.9 24.2 1.3e-08 34.8 13.1 2.9 2 1 0 2 2 2 2 AN1-like Zinc finger Ifi-6-16 PF06140.13 PRP86777.1 - 0.00022 21.0 24.9 0.00022 21.0 24.9 2.0 1 1 1 2 2 2 1 Interferon-induced 6-16 family zf-P11 PF03854.14 PRP86777.1 - 0.0062 16.2 4.4 0.017 14.8 4.4 1.7 1 0 0 1 1 1 1 P-11 zinc finger Grp7_allergen PF16984.5 PRP86777.1 - 0.22 11.6 0.1 0.38 10.8 0.1 1.3 1 0 0 1 1 1 0 Group 7 allergen Plus-3 PF03126.18 PRP86778.1 - 2.3e-24 86.0 0.0 8.7e-24 84.2 0.0 2.1 1 0 0 1 1 1 1 Plus-3 domain Peroxidase_2 PF01328.17 PRP86779.1 - 5.3e-53 180.3 0.0 9.7e-53 179.5 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 DNA_ligase_OB_2 PF14743.6 PRP86779.1 - 3.3e-28 97.5 0.6 7.8e-28 96.3 0.6 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain zf-CCHH PF10283.9 PRP86779.1 - 2.2e-19 69.1 14.2 8.3e-10 38.5 1.4 3.5 3 0 0 3 3 3 3 PBZ domain DNA_ligase_A_M PF01068.21 PRP86779.1 - 3.7e-12 46.3 0.0 1.1e-11 44.8 0.0 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Toxin_24 PF08094.11 PRP86779.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.5 3 0 0 3 3 3 0 Conotoxin TVIIA/GS family DNA_ligase_A_C PF04679.15 PRP86779.1 - 0.88 10.2 5.3 1.8 9.2 0.0 3.3 3 1 1 4 4 4 0 ATP dependent DNA ligase C terminal region zf-CCCH_4 PF18044.1 PRP86779.1 - 8.9 6.2 7.1 27 4.7 0.3 3.4 3 0 0 3 3 3 0 CCCH-type zinc finger MFS_1 PF07690.16 PRP86781.1 - 2.8e-25 89.0 37.8 1.2e-24 86.9 33.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 PRP86781.1 - 8.2e-17 60.8 15.8 1.1e-16 60.3 15.8 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector adh_short PF00106.25 PRP86782.1 - 1.4e-55 187.8 0.0 1.9e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP86782.1 - 1.1e-39 136.4 0.1 1.3e-39 136.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP86782.1 - 7.2e-14 52.1 0.1 1e-13 51.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP86782.1 - 1.5e-06 27.9 0.2 4.5e-06 26.3 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP86782.1 - 0.0062 16.0 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 PRP86782.1 - 0.095 13.0 0.8 0.16 12.2 0.2 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Na_Ca_ex_C PF16494.5 PRP86783.1 - 0.15 12.5 2.3 9.8 6.7 0.8 2.2 1 1 1 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain PH PF00169.29 PRP86784.1 - 0.0013 19.2 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 PRP86784.1 - 0.0033 16.9 0.2 0.011 15.2 0.2 2.0 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 PRP86784.1 - 0.0073 15.8 0.8 0.018 14.5 0.8 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 PRP86784.1 - 0.038 13.9 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 PRP86784.1 - 0.11 12.9 1.0 0.67 10.5 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain pair PH_11 PF15413.6 PRP86784.1 - 0.14 12.6 0.1 0.34 11.4 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Xpo1 PF08389.12 PRP86785.1 - 0.0059 16.7 0.5 0.76 9.8 0.0 3.9 4 0 0 4 4 4 1 Exportin 1-like protein BPL_N PF09825.9 PRP86786.1 - 1.7e-17 63.6 0.0 6.1e-11 42.0 0.0 2.1 2 0 0 2 2 2 2 Biotin-protein ligase, N terminal GATase PF00117.28 PRP86786.1 - 0.0044 16.8 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 PRP86786.1 - 0.0051 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 PRP86786.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Ifi-6-16 PF06140.13 PRP86787.1 - 8.1e-05 22.5 25.8 8.5e-05 22.4 23.9 2.0 1 1 0 1 1 1 1 Interferon-induced 6-16 family Stealth_CR2 PF11380.8 PRP86788.1 - 4.4e-26 91.2 2.4 2.7e-24 85.4 0.9 2.8 2 1 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 PRP86788.1 - 5.1e-11 42.3 0.4 1e-10 41.3 0.4 1.5 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 PRP86788.1 - 5.1e-05 23.1 0.0 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 DUF2115 PF09888.9 PRP86788.1 - 0.15 12.6 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) RhoGAP PF00620.27 PRP86790.1 - 4.2e-25 88.3 0.0 6.8e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain GRAM PF02893.20 PRP86790.1 - 1.3e-06 28.3 0.1 0.00038 20.3 0.0 3.1 3 0 0 3 3 3 1 GRAM domain SWIB PF02201.18 PRP86790.1 - 0.0065 16.3 0.0 0.033 14.1 0.0 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain Vps36_ESCRT-II PF11605.8 PRP86790.1 - 0.11 12.6 0.0 2.4 8.4 0.0 2.7 3 0 0 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 UQ_con PF00179.26 PRP86791.1 - 2.2e-49 166.7 0.1 4e-49 165.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RasGEF PF00617.19 PRP86791.1 - 1.3e-48 165.5 0.0 2.6e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain AA_kinase PF00696.28 PRP86791.1 - 8.3e-24 84.5 0.0 1.3e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family RasGEF_N PF00618.20 PRP86791.1 - 5.7e-16 58.7 0.6 2.1e-15 56.8 0.6 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 PRP86791.1 - 1.1e-07 31.6 0.1 5.4e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 PRP86791.1 - 1.3e-05 24.6 2.1 0.0002 20.9 0.0 3.0 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.17 PRP86791.1 - 0.0022 17.7 0.0 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain DRIM PF07539.12 PRP86793.1 - 8.3e-52 176.3 6.8 8.3e-52 176.3 6.8 4.2 3 1 0 3 3 3 1 Down-regulated in metastasis RTP1_C1 PF10363.9 PRP86793.1 - 6.6e-06 26.3 0.1 0.4 10.9 0.0 3.9 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Hydrolase_4 PF12146.8 PRP86793.1 - 0.00011 21.6 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF818 PF05677.12 PRP86793.1 - 0.00059 18.9 0.0 0.0014 17.6 0.0 1.6 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_6 PF12697.7 PRP86793.1 - 0.0012 19.4 0.5 0.003 18.2 0.5 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family UNC45-central PF11701.8 PRP86793.1 - 0.0018 18.2 10.5 0.054 13.4 0.1 5.6 6 0 0 6 6 6 2 Myosin-binding striated muscle assembly central Lipase_3 PF01764.25 PRP86793.1 - 0.026 14.4 0.1 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) ParcG PF10274.9 PRP86793.1 - 0.077 13.1 3.0 5.1 7.2 0.1 4.7 6 0 0 6 6 6 0 Parkin co-regulated protein DED PF01335.21 PRP86793.1 - 0.79 10.1 5.8 4.6 7.6 0.6 3.5 2 0 0 2 2 2 0 Death effector domain Arm PF00514.23 PRP86795.1 - 1.8e-06 27.8 0.3 0.007 16.4 0.1 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PRP86795.1 - 0.017 15.3 0.1 0.17 12.2 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat NopRA1 PF16201.5 PRP86795.1 - 0.068 12.7 0.1 0.27 10.8 0.1 1.8 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 PRP86795.1 - 0.11 12.6 0.2 1.6 8.8 0.1 2.3 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Metallophos PF00149.28 PRP86796.1 - 2.7e-39 135.8 0.0 3.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PRP86796.1 - 3.3e-22 78.6 1.0 8.7e-22 77.3 1.0 1.8 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain EF-hand_1 PF00036.32 PRP86796.1 - 5.1e-12 44.4 1.1 1.1e-05 24.6 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PRP86796.1 - 1.7e-10 41.2 4.7 1.7e-08 34.8 1.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP86796.1 - 5.9e-10 38.3 0.2 0.0016 18.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PRP86796.1 - 6e-10 38.2 0.7 0.00029 20.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PRP86796.1 - 3.3e-05 23.6 0.3 0.012 15.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP86796.1 - 0.1 12.9 0.0 6.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region fn3 PF00041.21 PRP86797.1 - 0.0016 18.8 12.4 0.075 13.4 0.1 5.3 6 0 0 6 6 6 2 Fibronectin type III domain MMPL PF03176.15 PRP86797.1 - 0.083 11.8 0.4 0.13 11.2 0.4 1.2 1 0 0 1 1 1 0 MMPL family TPT PF03151.16 PRP86798.1 - 1.4e-25 90.3 23.5 1.7e-25 90.0 23.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PRP86798.1 - 0.0018 17.5 23.9 0.0029 16.8 23.9 1.3 1 0 0 1 1 1 1 UAA transporter family LRR_6 PF13516.6 PRP86799.1 - 4.4e-14 51.3 27.9 0.00012 21.8 0.2 9.8 10 0 0 10 10 10 4 Leucine Rich repeat RasGAP PF00616.19 PRP86799.1 - 6.5e-12 45.6 0.0 3.9e-09 36.5 0.0 3.4 2 1 1 3 3 3 1 GTPase-activator protein for Ras-like GTPase LRR_4 PF12799.7 PRP86799.1 - 0.01 16.2 25.0 0.22 12.0 1.1 5.3 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP86799.1 - 0.18 12.5 6.6 2.8e+02 2.7 0.0 6.5 6 2 0 6 6 6 0 Leucine Rich Repeat Zn_clus PF00172.18 PRP86801.1 - 3.6e-06 27.0 15.1 3.6e-06 27.0 15.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.12 PRP86801.1 - 1.5e-05 25.2 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 PRP86801.1 - 0.00021 21.3 0.1 0.00059 19.8 0.1 1.7 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 PRP86801.1 - 0.036 14.3 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.7 PRP86801.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF5310 PF17237.2 PRP86801.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5310) tRNA-synt_1b PF00579.25 PRP86802.1 - 2e-73 247.3 0.0 3.3e-73 246.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 PRP86802.1 - 0.00083 19.0 0.1 0.0017 18.0 0.1 1.5 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 PRP86802.1 - 0.07 12.9 0.1 2 8.2 0.1 2.6 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Arg_decarbox_C PF17944.1 PRP86802.1 - 0.12 13.0 0.8 0.39 11.3 0.1 2.3 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension RhoGEF PF00621.20 PRP86803.1 - 6.2e-45 153.7 4.7 6.2e-45 153.7 4.7 3.0 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 PRP86803.1 - 0.00013 22.4 0.0 0.00042 20.8 0.0 2.0 1 0 0 1 1 1 1 PH domain IQ PF00612.27 PRP86803.1 - 0.00022 20.8 0.2 0.00066 19.2 0.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ_SEC7_PH PF16453.5 PRP86803.1 - 0.0054 16.7 0.6 0.029 14.4 0.1 2.6 2 1 0 2 2 2 1 PH domain DNApol3-delta_C PF09115.10 PRP86803.1 - 2.6 8.6 9.4 14 6.3 0.7 3.8 4 0 0 4 4 4 0 DNA polymerase III, delta subunit, C terminal Methyltransf_11 PF08241.12 PRP86804.1 - 0.00022 21.8 0.0 0.00068 20.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PRP86804.1 - 0.021 15.5 0.0 0.053 14.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 PRP86804.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 PRP86804.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family NTP_transferase PF00483.23 PRP86805.1 - 7.4e-21 74.9 0.1 1.8e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 PRP86805.1 - 3.3e-11 43.8 0.0 4.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 PRP86805.1 - 3.1e-06 26.4 5.5 3.1e-06 26.4 5.5 2.1 2 2 1 3 3 3 1 L-fucokinase Hexapep PF00132.24 PRP86805.1 - 9.1e-05 22.0 18.1 0.001 18.7 3.3 4.0 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 PRP86805.1 - 0.00089 17.5 4.6 0.0019 16.4 4.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) B_solenoid_ydck PF18836.1 PRP86805.1 - 0.3 11.0 0.7 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Beta solenoid repeat from YDCK Hexapep_2 PF14602.6 PRP86805.1 - 1.8 8.4 14.0 1.7 8.5 5.7 3.6 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase RHD3 PF05879.12 PRP86806.1 - 1.2e-178 595.7 16.5 8.9e-177 589.5 16.5 2.4 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) AZUL PF16558.5 PRP86806.1 - 1.7e-20 73.0 11.0 3.8e-11 43.0 1.3 2.9 2 0 0 2 2 2 2 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A GBP PF02263.19 PRP86806.1 - 3.7e-06 26.4 0.1 1.2e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 PRP86806.1 - 3e-05 24.1 0.0 0.00014 21.9 0.0 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PRP86806.1 - 0.0029 17.7 0.0 0.0029 17.7 0.0 3.4 4 0 0 4 4 4 1 Dynamin family AAA_28 PF13521.6 PRP86806.1 - 0.014 15.6 0.1 0.014 15.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain SWIM PF04434.17 PRP86806.1 - 0.017 14.8 0.1 0.034 13.8 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger ABC_tran PF00005.27 PRP86806.1 - 0.091 13.3 5.2 0.14 12.6 0.0 3.4 3 0 0 3 3 3 0 ABC transporter GAS PF13851.6 PRP86807.1 - 1.5e-08 34.3 35.5 1.2e-07 31.3 5.0 3.3 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding ERM PF00769.19 PRP86807.1 - 0.0003 20.7 21.0 0.0003 20.7 21.0 2.5 1 1 1 2 2 2 1 Ezrin/radixin/moesin family DUF812 PF05667.11 PRP86807.1 - 0.0097 14.8 24.5 0.014 14.3 24.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Phage_GP20 PF06810.11 PRP86807.1 - 0.012 15.4 2.3 0.012 15.4 2.3 3.6 2 1 2 4 4 4 0 Phage minor structural protein GP20 TAF6_C PF07571.13 PRP86807.1 - 0.14 12.5 2.2 2.4 8.5 0.2 2.4 1 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain DUF5082 PF16888.5 PRP86807.1 - 0.2 11.9 24.5 0.58 10.4 0.3 4.4 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Sec2p PF06428.11 PRP86807.1 - 0.28 11.2 33.7 0.22 11.5 12.1 4.5 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF3584 PF12128.8 PRP86807.1 - 0.28 8.6 27.8 0.39 8.2 27.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 PRP86807.1 - 0.28 10.5 20.1 0.081 12.3 16.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF664 PF04978.12 PRP86807.1 - 0.55 10.6 5.7 0.52 10.7 2.9 2.4 2 1 1 3 3 2 0 Protein of unknown function (DUF664) DUF4201 PF13870.6 PRP86807.1 - 0.58 9.9 28.4 5.5 6.7 15.5 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) PRKG1_interact PF15898.5 PRP86807.1 - 0.82 10.6 35.1 7.4 7.5 19.6 3.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain HMMR_N PF15905.5 PRP86807.1 - 1.1 8.6 34.1 1.4 8.3 32.8 1.8 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MinE PF03776.14 PRP86807.1 - 1.7 8.7 8.2 20 5.2 0.0 3.7 4 1 0 4 4 4 0 Septum formation topological specificity factor MinE Spc7 PF08317.11 PRP86807.1 - 1.7 7.5 35.7 0.082 11.8 7.6 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein POTRA_TamA_1 PF17243.2 PRP86807.1 - 2.6 8.2 7.0 0.51 10.5 0.2 2.9 1 1 3 4 4 4 0 POTRA domain TamA domain 1 DUF3800 PF12686.7 PRP86807.1 - 2.7 8.7 4.8 1.3e+02 3.2 4.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) ATG16 PF08614.11 PRP86807.1 - 4 7.6 34.5 0.41 10.8 6.0 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 PRP86807.1 - 4.2 7.7 7.3 6.5 7.1 0.1 3.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.6 PRP86807.1 - 5.3 7.2 29.4 0.12 12.5 15.5 3.2 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 SlyX PF04102.12 PRP86807.1 - 5.4 7.7 33.9 0.79 10.4 0.5 5.5 1 1 4 5 5 5 0 SlyX UPF0242 PF06785.11 PRP86807.1 - 6.2 6.9 38.5 12 5.9 8.3 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rx_N PF18052.1 PRP86807.1 - 7.2 7.0 18.4 0.15 12.4 1.1 3.8 1 1 3 4 4 4 0 Rx N-terminal domain Cob_adeno_trans PF01923.18 PRP86807.1 - 7.6 6.6 17.4 26 4.9 6.2 3.0 2 1 1 3 3 3 0 Cobalamin adenosyltransferase FmiP_Thoc5 PF09766.9 PRP86807.1 - 8.5 5.5 29.8 4.6 6.4 2.6 3.0 1 1 2 3 3 3 0 Fms-interacting protein/Thoc5 Med9 PF07544.13 PRP86807.1 - 8.9 6.5 25.9 2.5 8.3 1.5 3.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fibin PF15819.5 PRP86808.1 - 0.045 13.5 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Fin bud initiation factor homologue CH PF00307.31 PRP86810.1 - 1.4e-14 54.2 0.3 4.3e-14 52.6 0.1 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain SH3_2 PF07653.17 PRP86810.1 - 4.1e-11 42.4 0.1 1.3e-10 40.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 PRP86810.1 - 4.8e-11 42.1 0.2 9.6e-11 41.1 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP86810.1 - 1.8e-09 37.3 0.0 3.8e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 PRP86810.1 - 8.2e-07 29.5 0.0 1.7e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 PH domain BCL_N PF04714.13 PRP86810.1 - 4.1e-06 26.8 1.2 4.1e-06 26.8 1.2 3.1 2 0 0 2 2 2 1 BCL7, N-terminal conserver region MSA-2c PF12238.8 PRP86810.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 5.2 3 1 2 5 5 5 1 Merozoite surface antigen 2c CDC24 PF06395.11 PRP86810.1 - 0.0057 16.9 0.4 0.029 14.6 0.0 2.3 2 0 0 2 2 2 1 CDC24 Calponin CENP-F_leu_zip PF10473.9 PRP86810.1 - 0.033 14.2 32.7 0.24 11.4 8.2 3.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 PRP86810.1 - 3.8 6.7 25.4 2.1 7.6 21.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prenylcys_lyase PF07156.14 PRP86811.1 - 3.1e-74 250.2 0.0 4.1e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 PRP86811.1 - 1.4e-10 41.1 0.0 2e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP86811.1 - 1.3e-07 31.7 0.4 2.8e-07 30.6 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PRP86811.1 - 1.4e-05 25.1 0.5 0.22 11.5 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 PRP86811.1 - 0.0021 17.7 0.5 0.0039 16.8 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP86811.1 - 0.0021 17.3 0.1 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1797 PF08796.10 PRP86811.1 - 0.12 12.5 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) F420_oxidored PF03807.17 PRP86811.1 - 0.14 12.8 0.6 8.9 7.0 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF547 PF04784.14 PRP86812.1 - 7.3e-09 35.7 0.0 1.8e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.21 PRP86812.1 - 8.1e-05 22.6 0.0 0.00029 20.8 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Mito_carr PF00153.27 PRP86813.1 - 1.1e-55 185.5 2.8 1.1e-23 83.0 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PNK3P PF08645.11 PRP86814.1 - 3.3e-51 173.2 0.1 6.1e-51 172.3 0.1 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 PRP86814.1 - 1.8e-12 47.7 0.0 4.5e-10 39.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 PRP86814.1 - 0.0002 20.9 0.4 0.065 12.7 0.4 2.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 6PF2K PF01591.18 PRP86814.1 - 0.064 12.6 0.1 3.4 6.9 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_16 PF13191.6 PRP86814.1 - 0.1 13.0 0.5 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain CDC27 PF09507.10 PRP86814.1 - 5 6.4 40.6 7.7 5.8 40.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.9 PRP86814.1 - 5.1 5.8 35.0 7.4 5.3 35.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4598 PF15370.6 PRP86815.1 - 8.5e-14 52.0 3.2 8.5e-14 52.0 3.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) SVIP PF15811.5 PRP86816.1 - 9.8e-07 29.1 3.2 1.1e-06 29.0 3.2 1.2 1 0 0 1 1 1 1 Small VCP/p97-interacting protein Sec3_C PF09763.9 PRP86817.1 - 1.4e-80 271.7 39.2 2.4e-41 142.0 16.3 2.1 1 1 1 2 2 2 2 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 PRP86817.1 - 3.5e-14 52.7 0.1 1.5e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH HCMV_UL139 PF12507.8 PRP86817.1 - 0.059 13.7 1.9 0.18 12.2 0.8 2.3 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Laminin_II PF06009.12 PRP86817.1 - 0.11 12.6 12.4 0.065 13.2 2.8 3.5 2 1 1 3 3 3 0 Laminin Domain II Seryl_tRNA_N PF02403.22 PRP86817.1 - 7.3 6.9 13.7 9.6 6.5 0.0 3.8 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain CIA30 PF08547.12 PRP86818.1 - 2.8e-32 111.9 0.0 4e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 PRP86818.1 - 0.02 14.8 0.1 0.039 13.8 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) RNA_pol_A_bac PF01000.26 PRP86819.1 - 2.5e-29 101.9 0.0 6.8e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PRP86819.1 - 4.6e-21 74.0 0.0 1e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 PRP86819.1 - 0.028 14.6 1.6 0.077 13.2 1.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 PRP86819.1 - 0.033 14.8 1.8 0.08 13.5 1.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 PRP86819.1 - 0.35 11.0 1.5 0.78 9.9 1.5 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain AMP-binding PF00501.28 PRP86821.1 - 4.7e-85 285.7 0.7 7.1e-85 285.1 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP86821.1 - 1.4e-24 86.8 1.3 2.3e-24 86.2 0.5 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 PRP86821.1 - 3.4e-20 71.7 1.2 8e-20 70.5 1.2 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Tmemb_185A PF10269.9 PRP86821.1 - 3.2e-19 69.6 20.2 3.2e-19 69.6 20.2 1.6 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein DnaJ PF00226.31 PRP86821.1 - 3.6e-19 68.6 1.1 1.2e-18 67.0 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain DIOX_N PF14226.6 PRP86823.1 - 9.1e-34 116.7 0.0 1.6e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PRP86823.1 - 3.7e-21 75.5 0.0 7.7e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rap_GAP PF02145.15 PRP86824.1 - 2.1e-52 177.4 0.0 1.1e-51 175.0 0.0 2.2 2 0 0 2 2 2 1 Rap/ran-GAP Ank_2 PF12796.7 PRP86824.1 - 1.2e-28 99.5 0.1 6.6e-13 49.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP86824.1 - 1.3e-26 92.6 0.3 2e-08 34.6 0.2 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP86824.1 - 5.6e-24 83.9 2.1 1.8e-08 34.4 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP86824.1 - 8.3e-24 83.0 0.2 9e-06 25.9 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 PRP86824.1 - 1.7e-21 74.0 0.1 4.8e-05 23.4 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat F-box-like PF12937.7 PRP86824.1 - 9.4e-08 31.8 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP86824.1 - 6e-07 29.2 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Ras PF00071.22 PRP86824.1 - 0.034 13.7 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Ras family F-box_4 PF15966.5 PRP86824.1 - 0.067 13.1 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 F-box CH PF00307.31 PRP86825.1 - 1.2e-21 76.9 0.0 2.7e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain PH PF00169.29 PRP86825.1 - 7.7e-17 61.7 0.5 1.1e-09 38.7 0.1 3.4 3 0 0 3 3 3 2 PH domain LIM PF00412.22 PRP86825.1 - 5.6e-09 36.1 4.6 5.6e-09 36.1 4.6 3.8 4 0 0 4 4 4 1 LIM domain Cupin_8 PF13621.6 PRP86825.1 - 3.5e-05 23.6 0.0 0.0001 22.1 0.0 1.8 1 0 0 1 1 1 1 Cupin-like domain CAMSAP_CH PF11971.8 PRP86825.1 - 9.9e-05 22.1 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain PH_11 PF15413.6 PRP86825.1 - 0.00035 21.0 1.7 0.11 13.0 0.5 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain RhoGAP PF00620.27 PRP86826.1 - 9.6e-19 67.7 0.0 1.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FERM_f0 PF16511.5 PRP86826.1 - 3.4e-10 40.1 1.3 8.8e-05 22.7 0.0 3.4 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM ubiquitin PF00240.23 PRP86826.1 - 0.0046 16.7 0.6 2.2 8.1 0.0 3.4 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.8 PRP86826.1 - 0.073 12.9 0.1 3 7.8 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like RTP1_C1 PF10363.9 PRP86827.1 - 3.5e-33 114.1 1.2 1.4e-30 105.8 0.2 3.3 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 PRP86827.1 - 4.4e-08 32.7 0.4 4.4e-08 32.7 0.4 2.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 PRP86827.1 - 7.8e-06 26.2 0.0 0.062 13.7 0.0 4.4 5 2 1 6 6 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 PRP86827.1 - 1.7e-05 25.3 0.4 0.019 15.5 0.0 3.5 4 0 0 4 4 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 PRP86827.1 - 3.5e-05 23.7 0.4 3.9 8.0 0.1 4.6 4 0 0 4 4 3 1 HEAT repeat UME PF08064.13 PRP86827.1 - 0.00033 20.5 4.7 0.22 11.5 0.0 4.3 5 1 1 6 6 6 2 UME (NUC010) domain HEAT_EZ PF13513.6 PRP86827.1 - 0.0011 19.4 1.2 0.075 13.6 0.0 4.5 5 0 0 5 5 5 1 HEAT-like repeat MMS19_N PF14500.6 PRP86827.1 - 0.0013 18.4 1.0 0.022 14.3 0.3 2.4 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF3385 PF11865.8 PRP86827.1 - 0.0018 18.2 2.8 0.0062 16.5 0.0 3.3 5 0 0 5 5 4 1 Domain of unknown function (DUF3385) IBN_N PF03810.19 PRP86827.1 - 0.014 15.3 0.1 0.12 12.3 0.0 2.5 2 0 0 2 2 2 0 Importin-beta N-terminal domain Adaptin_N PF01602.20 PRP86827.1 - 0.017 13.7 1.9 0.65 8.5 0.1 2.8 2 1 0 3 3 3 0 Adaptin N terminal region Cnd1 PF12717.7 PRP86827.1 - 0.025 14.6 1.7 2.7 8.0 0.1 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF4355 PF14265.6 PRP86827.1 - 0.027 14.7 0.2 0.33 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) UNC45-central PF11701.8 PRP86827.1 - 0.056 13.4 2.2 0.95 9.4 0.0 3.3 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central putAbiC PF16872.5 PRP86827.1 - 0.13 13.0 0.2 12 6.7 0.0 2.8 2 0 0 2 2 2 0 Putative phage abortive infection protein DUF389 PF04087.14 PRP86828.1 - 0.072 13.1 1.1 0.11 12.5 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF389) Cas_Cas5d PF09704.10 PRP86828.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) PP2C PF00481.21 PRP86829.1 - 2.7e-44 151.8 0.0 2.7e-44 151.8 0.0 3.2 3 1 1 4 4 4 1 Protein phosphatase 2C AMP-binding PF00501.28 PRP86830.1 - 3.3e-91 306.0 0.0 4e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP86830.1 - 0.006 17.5 0.0 0.024 15.6 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CG-1 PF03859.16 PRP86831.1 - 8.2e-31 106.2 0.0 3.1e-30 104.3 0.0 2.1 1 0 0 1 1 1 1 CG-1 domain TIG PF01833.24 PRP86831.1 - 1.9e-11 43.9 0.1 3.8e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 IPT/TIG domain Ank_4 PF13637.6 PRP86831.1 - 4.8e-10 39.8 0.3 2.9e-08 34.1 0.4 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP86831.1 - 1.1e-06 28.4 0.3 0.036 14.6 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 PRP86831.1 - 2.9e-06 27.5 1.1 0.00054 20.3 0.4 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 PRP86831.1 - 2.2e-05 25.0 0.0 6.6e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP86831.1 - 7.9e-05 22.9 0.0 0.011 16.1 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG_plexin PF17960.1 PRP86831.1 - 0.0085 16.1 0.0 0.031 14.2 0.0 2.0 1 0 0 1 1 1 1 TIG domain IQ PF00612.27 PRP86831.1 - 0.02 14.6 19.6 0.11 12.3 0.3 4.8 5 0 0 5 5 5 0 IQ calmodulin-binding motif MitMem_reg PF13012.6 PRP86832.1 - 7.6e-34 116.5 1.5 1.5e-33 115.5 1.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PRP86832.1 - 1.2e-29 102.7 2.4 3e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF1682 PF07946.14 PRP86832.1 - 0.0037 16.5 6.7 0.0052 16.0 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Connexin PF00029.19 PRP86832.1 - 0.5 10.1 8.8 1.5 8.6 8.8 1.8 1 1 0 1 1 1 0 Connexin Peroxin-13_N PF04088.13 PRP86832.1 - 1.2 9.4 3.8 2.1 8.6 3.8 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region MscS_TM PF12794.7 PRP86832.1 - 1.4 7.7 3.2 2 7.2 3.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Cpn60_TCP1 PF00118.24 PRP86833.1 - 2.9e-159 530.8 5.0 3.4e-159 530.6 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase_Tyr PF07714.17 PRP86835.1 - 1.1e-74 250.9 0.0 1.6e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP86835.1 - 1e-72 239.7 116.2 8.2e-09 35.1 2.0 20.8 14 5 8 22 22 22 19 Leucine rich repeat Pkinase PF00069.25 PRP86835.1 - 1.3e-53 182.1 0.0 2e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP86835.1 - 1.7e-46 155.4 143.2 0.00042 20.6 0.6 27.2 23 5 4 29 29 27 18 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP86835.1 - 4.1e-11 41.8 98.0 5.8 7.9 0.0 33.1 39 6 0 39 39 32 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP86835.1 - 5.3e-09 35.4 79.8 5.9 7.2 0.2 27.6 33 0 0 33 33 29 2 Leucine Rich repeat ASFV_J13L PF05568.11 PRP86835.1 - 0.069 12.9 0.7 0.15 11.8 0.7 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein DAP10 PF07213.11 PRP86835.1 - 0.073 13.0 1.1 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 DAP10 membrane protein Pkinase_fungal PF17667.1 PRP86835.1 - 0.084 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Amnionless PF14828.6 PRP86835.1 - 0.094 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Amnionless Kdo PF06293.14 PRP86835.1 - 0.22 10.8 0.1 0.42 9.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vpu PF00558.19 PRP86835.1 - 0.3 10.9 0.7 0.64 9.8 0.7 1.5 1 0 0 1 1 1 0 Vpu protein Syndecan PF01034.20 PRP86835.1 - 0.33 10.9 3.3 0.74 9.8 3.3 1.5 1 0 0 1 1 1 0 Syndecan domain TFIID-31kDa PF02291.15 PRP86835.1 - 0.36 10.9 2.8 0.6 10.2 0.1 2.7 3 1 0 3 3 3 0 Transcription initiation factor IID, 31kD subunit Adeno_E3_CR2 PF02439.15 PRP86835.1 - 1.2 8.9 4.6 2.2 8.1 4.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_5 PF13306.6 PRP86835.1 - 1.3 9.0 8.7 6.3 6.8 1.8 4.2 4 0 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) LRRNT_2 PF08263.12 PRP86835.1 - 7.9 6.9 6.1 2.6 8.4 2.7 2.1 2 0 0 2 2 1 0 Leucine rich repeat N-terminal domain Pkinase PF00069.25 PRP86836.1 - 6.6e-55 186.3 3.1 2.2e-52 178.1 3.1 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86836.1 - 4e-32 111.5 0.3 6.7e-29 100.9 0.3 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP86836.1 - 7e-07 28.5 0.2 9.1e-07 28.1 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PRP86836.1 - 0.00067 19.3 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PRP86836.1 - 0.02 14.2 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP86836.1 - 0.065 13.1 0.1 0.16 11.8 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Rad9_Rad53_bind PF08605.10 PRP86836.1 - 0.097 12.9 0.3 0.24 11.6 0.0 1.7 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding Kinase-like PF14531.6 PRP86836.1 - 0.1 11.9 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APG9 PF04109.16 PRP86837.1 - 8.3e-158 526.3 14.0 1.1e-157 526.0 14.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 SpoU_methylase PF00588.19 PRP86838.1 - 6.5e-15 55.5 0.0 1.2e-12 48.2 0.0 2.1 1 1 0 1 1 1 1 SpoU rRNA Methylase family CH PF00307.31 PRP86839.1 - 1.3e-34 118.6 0.1 3.2e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CH_2 PF06294.11 PRP86839.1 - 0.00011 22.2 0.0 0.63 10.2 0.0 2.6 2 0 0 2 2 2 2 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PRP86839.1 - 0.00049 19.9 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain Spc7 PF08317.11 PRP86839.1 - 0.0019 17.2 17.2 0.0019 17.2 17.2 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein Syntaxin_2 PF14523.6 PRP86839.1 - 0.44 10.9 5.3 0.4 11.1 0.8 2.9 3 2 0 3 3 2 0 Syntaxin-like protein DUF1664 PF07889.12 PRP86839.1 - 0.72 9.9 9.0 5.1 7.2 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 PRP86839.1 - 0.79 10.1 25.2 4.7 7.6 25.2 2.1 1 1 0 1 1 1 0 Fez1 CENP-F_leu_zip PF10473.9 PRP86839.1 - 0.91 9.5 30.6 0.021 14.8 17.3 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 PRP86839.1 - 1.1 9.6 24.6 0.21 12.0 5.3 4.4 3 1 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 PRP86839.1 - 1.9 6.9 3.3 3 6.3 3.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRE1 PF08647.11 PRP86839.1 - 2.1 8.5 26.6 1.3 9.1 4.9 3.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase KASH_CCD PF14662.6 PRP86839.1 - 3.2 7.5 28.1 0.054 13.3 17.4 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4407 PF14362.6 PRP86839.1 - 5.4 6.3 17.5 54 3.0 17.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 PRP86839.1 - 6.8 6.9 7.8 0.82 9.8 1.6 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 PRP86839.1 - 6.8 6.1 22.6 1.1 8.7 17.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 AAA_5 PF07728.14 PRP86841.1 - 4.6e-15 55.8 0.0 9.8e-13 48.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 PRP86841.1 - 8.8e-07 29.4 0.0 3.9e-06 27.3 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 PRP86841.1 - 0.00096 18.3 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.6 PRP86841.1 - 0.0024 18.3 0.0 0.011 16.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 PRP86841.1 - 0.0028 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_7 PF12775.7 PRP86841.1 - 0.0047 16.5 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 PRP86841.1 - 0.0083 16.7 0.0 0.069 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP86841.1 - 0.012 16.0 0.0 0.045 14.2 0.0 2.0 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 PRP86841.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein 6PF2K PF01591.18 PRP86841.1 - 0.045 13.1 0.0 0.91 8.8 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Mg_chelatase PF01078.21 PRP86841.1 - 0.055 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PPV_E1_C PF00519.17 PRP86841.1 - 0.056 12.3 0.0 0.095 11.5 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase Sigma54_activat PF00158.26 PRP86841.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 PRP86841.1 - 0.059 13.6 0.0 0.2 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PRP86841.1 - 0.08 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain HA PF03457.14 PRP86842.1 - 7.8e-15 55.0 1.4 1.7e-14 53.8 1.4 1.6 1 0 0 1 1 1 1 Helicase associated domain FANCF PF11107.8 PRP86843.1 - 2.7e-06 26.8 0.0 1.5e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 Fanconi anemia group F protein (FANCF) Ank_4 PF13637.6 PRP86844.1 - 2.6e-14 53.4 7.7 0.039 14.5 0.0 8.8 3 3 6 10 10 10 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86844.1 - 1.8e-13 50.9 0.1 0.0026 18.3 0.0 5.3 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP86844.1 - 5.3e-09 36.2 4.1 0.072 13.4 0.0 7.5 5 2 3 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP86844.1 - 8.1e-08 32.0 3.3 15 6.6 0.0 8.8 11 0 0 11 11 11 1 Ankyrin repeat F-box PF00646.33 PRP86844.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF249 PF03158.13 PRP86844.1 - 0.014 15.1 0.1 12 5.5 0.0 3.6 3 1 0 3 3 3 0 Multigene family 530 protein F-box-like PF12937.7 PRP86844.1 - 0.026 14.4 0.0 0.069 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like TerY_C PF15616.6 PRP86844.1 - 0.46 10.6 1.5 4.4 7.4 0.1 2.7 2 1 0 2 2 2 0 TerY-C metal binding domain SAP PF02037.27 PRP86846.1 - 2.8e-05 23.7 0.3 6.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 SAP domain EF-hand_6 PF13405.6 PRP86847.1 - 0.0016 18.2 0.2 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF_assoc_2 PF08356.12 PRP86847.1 - 0.095 12.7 0.1 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 EF hand associated DUF1279 PF06916.13 PRP86848.1 - 4.6e-21 75.2 0.1 8.4e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PBP1_TM PF14812.6 PRP86848.1 - 0.0043 17.4 1.0 0.0074 16.6 1.0 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 PRP86848.1 - 0.0089 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 FAM176 family UBN_AB PF14075.6 PRP86848.1 - 0.23 11.2 4.3 0.33 10.7 4.3 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain TACC_C PF05010.14 PRP86854.1 - 0.0027 17.5 24.0 0.0027 17.5 24.0 3.1 1 1 2 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 PRP86854.1 - 0.23 11.5 22.7 0.035 14.1 10.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TetR_C_13 PF16925.5 PRP86854.1 - 1.1 9.2 8.3 0.097 12.6 1.5 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FUSC PF04632.12 PRP86854.1 - 2 6.9 8.2 0.37 9.3 4.2 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.6 PRP86854.1 - 6 6.2 52.9 0.51 9.6 19.4 3.1 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Glyco_transf_41 PF13844.6 PRP86855.1 - 1.4e-65 221.6 0.1 7.4e-32 110.4 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 HSA PF07529.13 PRP86855.1 - 0.0076 16.6 1.3 0.0076 16.6 1.3 2.8 2 0 0 2 2 2 1 HSA Tektin PF03148.14 PRP86855.1 - 0.94 8.2 4.5 1.8 7.3 0.7 2.5 3 0 0 3 3 3 0 Tektin family PIG-P PF08510.12 PRP86856.1 - 4.7e-33 113.7 2.0 5.3e-33 113.5 2.0 1.0 1 0 0 1 1 1 1 PIG-P PP2C PF00481.21 PRP86857.1 - 5e-25 88.6 0.1 5.8e-16 58.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PRP86857.1 - 6.1e-10 39.1 0.2 0.00013 21.7 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PRP86857.1 - 2.5e-07 30.8 0.0 0.00047 20.1 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) ApbA_C PF08546.11 PRP86857.1 - 0.093 12.9 0.1 0.92 9.7 0.0 2.5 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA C terminal IPK PF03770.16 PRP86858.1 - 7.7e-47 159.7 0.0 7.7e-47 159.7 0.0 2.1 2 1 0 2 2 1 1 Inositol polyphosphate kinase Mitofilin PF09731.9 PRP86858.1 - 6.4e-06 25.3 35.7 9.8e-06 24.7 35.7 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ApoLp-III PF07464.11 PRP86858.1 - 0.0045 17.1 24.5 0.0045 17.1 24.5 2.4 2 1 1 3 3 3 1 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 PRP86858.1 - 0.0071 16.9 40.1 1.8e+04 -9.6 40.1 4.0 1 1 0 1 1 0 0 YtxH-like protein DUF883 PF05957.13 PRP86858.1 - 0.012 16.2 45.6 0.86 10.2 12.0 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Gag_p10 PF02337.17 PRP86858.1 - 0.21 11.5 0.2 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Retroviral GAG p10 protein BAF1_ABF1 PF04684.13 PRP86858.1 - 0.24 10.4 20.3 0.31 10.0 20.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hamartin PF04388.12 PRP86858.1 - 0.32 9.6 10.2 0.31 9.6 10.2 1.2 1 0 0 1 1 1 0 Hamartin protein Apolipoprotein PF01442.18 PRP86858.1 - 0.33 10.8 39.8 6.1 6.7 39.4 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Macoilin PF09726.9 PRP86858.1 - 0.42 9.1 13.9 0.43 9.1 13.9 1.2 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 PRP86858.1 - 0.48 10.4 22.4 0.67 9.9 22.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Borrelia_P83 PF05262.11 PRP86858.1 - 1.8 6.9 39.4 3.3 6.1 39.4 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Phasin PF05597.11 PRP86858.1 - 2.1 8.3 32.7 0.35 10.9 1.6 3.5 2 1 2 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF966 PF06136.13 PRP86858.1 - 4 7.0 23.0 7.3 6.2 23.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SLC12 PF03522.15 PRP86858.1 - 4.1 6.3 17.0 7.3 5.5 17.0 1.4 1 0 0 1 1 1 0 Solute carrier family 12 ERM PF00769.19 PRP86858.1 - 7.3 6.3 38.0 13 5.5 38.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Rhomboid PF01694.22 PRP86860.1 - 2.1e-20 73.3 7.8 2.1e-20 73.3 7.8 2.2 2 1 1 3 3 3 1 Rhomboid family Peptidase_U4 PF03419.13 PRP86860.1 - 4.7 6.4 9.7 0.76 9.0 4.4 2.2 1 1 2 3 3 3 0 Sporulation factor SpoIIGA ATPase_2 PF01637.18 PRP86861.1 - 6.3e-05 23.0 0.0 0.00016 21.6 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea DUF3104 PF11302.8 PRP86861.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Cation_efflux PF01545.21 PRP86862.1 - 7.7e-45 153.1 11.2 7.7e-45 153.1 11.2 4.0 3 1 1 4 4 4 2 Cation efflux family Fil_haemagg_2 PF13332.6 PRP86862.1 - 0.15 12.1 0.8 0.24 11.5 0.8 1.2 1 0 0 1 1 1 0 Hemagglutinin repeat DUF962 PF06127.11 PRP86862.1 - 2.3 8.3 10.3 0.19 11.8 0.1 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF962) Cbl_N2 PF02761.14 PRP86863.1 - 3.5e-13 50.1 0.3 3.5e-13 50.1 0.3 2.2 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain zf-C3HC4_3 PF13920.6 PRP86863.1 - 2.6e-12 46.4 11.6 4e-12 45.8 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH2 PF00017.24 PRP86863.1 - 1.1e-08 35.0 0.0 4.1e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 SH2 domain Prok-RING_4 PF14447.6 PRP86863.1 - 0.02 14.7 11.7 0.034 14.0 11.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cbl_N3 PF02762.14 PRP86863.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain JMY PF15871.5 PRP86863.1 - 0.16 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein zf-RING_2 PF13639.6 PRP86863.1 - 0.33 11.3 13.0 0.61 10.5 13.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 PRP86863.1 - 1.2 9.2 12.0 2.6 8.1 12.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain FKBP_C PF00254.28 PRP86864.1 - 3.4e-33 113.8 0.0 4.3e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AAA PF00004.29 PRP86865.1 - 2.5e-41 141.2 0.0 5.2e-41 140.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP86865.1 - 4.2e-10 39.3 0.1 7.8e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PRP86865.1 - 1.9e-08 34.1 0.0 3.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 PRP86865.1 - 2.7e-05 24.4 0.0 6.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PRP86865.1 - 6.7e-05 23.2 0.3 0.023 15.0 0.3 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 PRP86865.1 - 9.7e-05 21.6 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 PRP86865.1 - 0.00074 19.5 0.2 0.0034 17.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP86865.1 - 0.00078 19.9 0.3 0.0046 17.3 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 PRP86865.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 PRP86865.1 - 0.007 15.7 0.1 0.36 10.1 0.1 2.4 1 1 1 2 2 2 1 KaiC AAA_33 PF13671.6 PRP86865.1 - 0.0077 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 PRP86865.1 - 0.0092 15.8 0.1 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PRP86865.1 - 0.013 16.0 0.1 0.043 14.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 PRP86865.1 - 0.036 13.8 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 PRP86865.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PRP86865.1 - 0.064 13.5 0.4 0.13 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 PRP86865.1 - 0.1 11.7 0.1 0.22 10.7 0.1 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 PRP86865.1 - 0.13 12.6 0.0 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 PRP86865.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 PRP86865.1 - 0.15 12.0 0.2 1 9.3 0.1 2.1 1 1 1 2 2 2 0 NACHT domain DUF2075 PF09848.9 PRP86865.1 - 0.15 11.3 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 PRP86865.1 - 0.2 11.4 0.6 0.48 10.1 0.3 1.8 2 1 0 2 2 2 0 AAA domain RasGEF PF00617.19 PRP86866.1 - 3.5e-30 105.5 0.0 6.1e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain ABC_tran PF00005.27 PRP86867.1 - 0.0023 18.5 0.0 0.003 18.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter Pkinase_Tyr PF07714.17 PRP86868.1 - 2.7e-70 236.6 0.0 4.2e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86868.1 - 3.9e-52 177.2 0.0 5.7e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP86868.1 - 9.7e-38 127.7 82.8 2.7e-10 39.9 1.7 12.9 8 2 7 15 15 15 13 Leucine rich repeat LRR_4 PF12799.7 PRP86868.1 - 1.5e-29 101.6 90.7 2.4e-05 24.6 0.5 16.4 9 4 10 21 21 21 17 Leucine Rich repeats (2 copies) Cellulase PF00150.18 PRP86868.1 - 4e-16 59.3 18.5 4.3e-10 39.5 1.2 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Kinase-like PF14531.6 PRP86868.1 - 7.1e-05 22.3 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 PRP86868.1 - 0.011 15.7 45.3 12 6.3 0.0 14.2 16 0 0 16 16 16 0 Leucine Rich repeat Insulin_TMD PF17870.1 PRP86868.1 - 0.037 14.1 0.4 0.12 12.4 0.4 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment LRR_1 PF00560.33 PRP86868.1 - 0.048 14.2 74.2 5.6 7.9 0.0 19.6 22 1 0 22 22 20 0 Leucine Rich Repeat Kdo PF06293.14 PRP86868.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP86868.1 - 0.095 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 PRP86869.1 - 1.6e-63 214.4 0.0 2.9e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86869.1 - 2.2e-47 161.6 0.0 3.4e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP86869.1 - 3.6e-31 106.7 68.9 0.0002 21.7 0.4 11.6 7 1 3 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP86869.1 - 7.2e-27 92.9 75.2 2.1e-06 27.4 2.9 9.8 5 2 7 12 12 12 10 Leucine rich repeat LRR_6 PF13516.6 PRP86869.1 - 1.5e-06 27.8 55.1 0.043 13.9 0.1 14.0 15 0 0 15 15 14 5 Leucine Rich repeat Adeno_E1B_55K PF01696.17 PRP86869.1 - 0.0056 15.4 1.3 0.48 9.1 0.5 2.6 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen Kdo PF06293.14 PRP86869.1 - 0.0094 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM154 PF15102.6 PRP86869.1 - 0.01 15.8 1.5 0.78 9.6 0.0 2.5 2 0 0 2 2 2 0 TMEM154 protein family Amnionless PF14828.6 PRP86869.1 - 0.032 13.1 0.1 0.076 11.8 0.0 1.6 2 0 0 2 2 2 0 Amnionless DUF347 PF03988.12 PRP86869.1 - 0.49 10.6 2.7 1.4 9.2 2.7 1.8 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) LRR_1 PF00560.33 PRP86869.1 - 0.57 10.9 54.5 3.6 8.5 0.1 15.0 15 2 0 15 15 13 0 Leucine Rich Repeat LRR_9 PF14580.6 PRP86869.1 - 0.78 9.2 12.7 1.6 8.2 0.1 4.3 3 2 1 5 5 5 0 Leucine-rich repeat Syndecan PF01034.20 PRP86869.1 - 7.9 6.5 7.0 18 5.3 7.0 1.6 1 0 0 1 1 1 0 Syndecan domain RNA_pol_Rpb2_6 PF00562.28 PRP86870.1 - 1.4e-128 429.3 0.3 2.3e-128 428.6 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Pkinase_Tyr PF07714.17 PRP86870.1 - 5.1e-63 212.8 0.0 8.2e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_pol_Rpb2_1 PF04563.15 PRP86870.1 - 5.8e-63 212.1 0.0 9.2e-63 211.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 PRP86870.1 - 9.8e-48 162.3 0.1 2.2e-47 161.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Pkinase PF00069.25 PRP86870.1 - 5.3e-45 153.8 0.0 8.5e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RNA_pol_Rpb2_7 PF04560.20 PRP86870.1 - 3.8e-34 116.9 0.1 9.2e-34 115.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 PRP86870.1 - 1.3e-26 92.5 0.0 3.1e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 PRP86870.1 - 1.5e-22 79.7 0.1 4e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 PRP86870.1 - 5.7e-16 58.8 0.1 2.7e-15 56.6 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 CUB PF00431.20 PRP86870.1 - 2.7e-07 30.9 0.0 6.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 CUB domain Kinase-like PF14531.6 PRP86870.1 - 0.06 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like OrfB_Zn_ribbon PF07282.11 PRP86870.1 - 0.15 12.0 0.3 0.52 10.3 0.3 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain EGF_2 PF07974.13 PRP86870.1 - 9.5 6.7 20.8 9.9 6.6 1.5 3.0 2 0 0 2 2 2 0 EGF-like domain Ank_2 PF12796.7 PRP86871.1 - 2.3e-19 69.8 0.2 1.4e-09 38.4 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP86871.1 - 8.8e-12 45.0 0.0 1.1e-09 38.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP86871.1 - 1.4e-09 38.3 0.0 3e-05 24.5 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP86871.1 - 2.4e-09 37.2 0.1 1.5e-05 25.2 0.0 3.9 3 2 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP86871.1 - 3.3e-07 30.1 0.0 0.00023 21.3 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeat UDG PF03167.19 PRP86872.1 - 2.5e-11 43.8 0.0 3.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pet127 PF08634.10 PRP86872.1 - 0.037 13.5 0.2 0.057 12.9 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet127 Ras PF00071.22 PRP86873.1 - 1.4e-54 184.0 0.1 2.5e-54 183.3 0.1 1.4 1 0 0 1 1 1 1 Ras family DUF3140 PF11338.8 PRP86873.1 - 2.4e-34 117.6 1.6 2.4e-34 117.6 1.6 3.9 4 1 0 4 4 4 1 Protein of unknown function (DUF3140) Roc PF08477.13 PRP86873.1 - 1.2e-19 70.7 0.5 1.8e-18 66.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Hva1_TUDOR PF11160.8 PRP86873.1 - 5e-18 65.0 1.5 5e-18 65.0 1.5 3.0 3 0 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain Arf PF00025.21 PRP86873.1 - 6.8e-09 35.4 0.1 3.5e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PRP86873.1 - 2.5e-06 27.5 0.1 0.0075 16.2 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP86873.1 - 0.001 19.2 0.0 0.0037 17.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP86873.1 - 0.0014 18.1 0.0 0.0064 16.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B eIF3_subunit PF08597.10 PRP86873.1 - 0.024 14.6 66.9 0.017 15.1 35.3 2.4 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Hamartin PF04388.12 PRP86873.1 - 5.3 5.6 33.2 6.8 5.2 33.2 1.2 1 0 0 1 1 1 0 Hamartin protein DUF1744 PF08490.12 PRP86874.1 - 1.2e-95 320.5 0.1 2.5e-95 319.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 PRP86874.1 - 1.4e-77 261.2 0.8 4.4e-77 259.5 0.8 2.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 PRP86874.1 - 3.9e-16 58.8 3.5 4.5e-08 32.2 0.0 4.6 5 0 0 5 5 5 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 PRP86874.1 - 1.5e-09 37.8 1.8 2.5e-09 37.1 0.3 2.2 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 PRP86874.1 - 1.5e-05 25.0 0.5 6.8e-05 22.9 0.1 2.4 2 0 0 2 2 2 1 RNase_H superfamily EDR1 PF14381.6 PRP86875.1 - 1.6e-25 90.0 0.0 9e-25 87.6 0.0 2.1 2 1 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 Nop PF01798.18 PRP86876.1 - 1.2e-83 280.1 0.0 1.2e-83 280.1 0.0 2.3 2 0 0 2 2 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PRP86876.1 - 3.5e-21 75.3 1.4 3.5e-21 75.3 1.4 2.9 2 1 0 2 2 1 1 NOP5NT (NUC127) domain DUF4704 PF15787.5 PRP86876.1 - 0.064 12.5 4.1 0.063 12.5 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) HEAT PF02985.22 PRP86876.1 - 0.12 12.7 2.4 2.5 8.6 0.0 4.1 4 0 0 4 4 3 0 HEAT repeat LAP1C PF05609.12 PRP86876.1 - 0.25 10.4 28.2 0.56 9.2 28.2 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 PRP86876.1 - 0.32 9.5 23.3 0.49 8.9 23.3 1.2 1 0 0 1 1 1 0 Macoilin family DUF4778 PF16008.5 PRP86876.1 - 0.61 10.1 19.7 1.6 8.7 19.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) RIX1 PF08167.12 PRP86876.1 - 0.67 9.7 6.4 4.7 6.9 1.0 2.8 1 1 0 2 2 2 0 rRNA processing/ribosome biogenesis TFIIF_alpha PF05793.12 PRP86876.1 - 1.3 7.5 54.7 2.1 6.8 54.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 PRP86876.1 - 5.7 5.6 30.6 9.7 4.8 30.6 1.4 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 PRP86876.1 - 6.5 3.7 19.2 8.7 3.3 19.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC27 PF09507.10 PRP86876.1 - 6.6 6.0 56.7 11 5.2 56.7 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hydin_ADK PF17213.3 PRP86876.1 - 9.6 6.4 14.7 28 4.9 14.7 2.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PPR_3 PF13812.6 PRP86877.1 - 4e-06 26.8 3.9 0.011 15.7 1.8 3.3 1 1 2 3 3 3 3 Pentatricopeptide repeat domain PAP2_C PF14360.6 PRP86878.1 - 3.2e-20 72.4 8.9 3.2e-20 72.4 8.9 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 PRP86878.1 - 0.0021 17.8 9.8 0.0021 17.8 9.8 2.3 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 PRP86878.1 - 0.0028 17.4 9.3 0.0028 17.4 9.3 2.6 1 1 1 2 2 2 1 PAP2 superfamily Amidohydro_2 PF04909.14 PRP86880.1 - 0.0088 15.8 0.1 0.025 14.4 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase Ish1 PF10281.9 PRP86880.1 - 0.017 15.4 0.5 26 5.2 0.0 3.5 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein F-box PF00646.33 PRP86880.1 - 0.067 13.1 0.3 0.22 11.5 0.3 1.9 1 0 0 1 1 1 0 F-box domain BCIP PF13862.6 PRP86881.1 - 1.3e-49 168.8 5.2 1.3e-49 168.8 5.2 2.2 2 0 0 2 2 2 1 p21-C-terminal region-binding protein CDC27 PF09507.10 PRP86881.1 - 0.45 9.8 32.8 0.093 12.1 26.6 2.3 2 1 0 2 2 2 0 DNA polymerase subunit Cdc27 Presenilin PF01080.17 PRP86881.1 - 0.46 9.2 10.2 0.074 11.8 6.6 1.4 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 PRP86881.1 - 0.95 8.6 6.0 1.5 7.9 6.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DAG_kinase_N PF14513.6 PRP86881.1 - 4.2 7.5 13.8 0.13 12.5 5.2 2.3 2 1 0 2 2 2 0 Diacylglycerol kinase N-terminus Stanniocalcin PF03298.13 PRP86882.1 - 0.0022 17.3 0.4 0.0043 16.4 0.4 1.4 1 0 0 1 1 1 1 Stanniocalcin family Pex14_N PF04695.13 PRP86882.1 - 0.0041 17.8 4.6 0.0041 17.8 4.6 2.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3586 PF12131.8 PRP86882.1 - 0.17 12.1 0.1 0.17 12.1 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3586) Pro_isomerase PF00160.21 PRP86884.1 - 3.7e-43 147.5 0.0 6.2e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD JmjC PF02373.22 PRP86884.1 - 2.4e-36 124.6 0.0 6.3e-36 123.3 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 PRP86884.1 - 6.6e-18 64.4 2.9 1.7e-17 63.1 2.9 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 PRP86884.1 - 4.6e-16 58.9 7.9 1.2e-15 57.7 7.9 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger RRM_1 PF00076.22 PRP86884.1 - 7.5e-16 57.7 0.2 2.1e-15 56.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ARID PF01388.21 PRP86884.1 - 3.8e-14 53.1 0.1 9e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Chromo PF00385.24 PRP86884.1 - 1.6e-05 24.7 0.2 4.3e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP86884.1 - 0.01 16.0 0.3 0.022 14.9 0.3 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 ASH PF15780.5 PRP86885.1 - 1.4e-77 256.1 73.5 2.3e-06 27.7 0.1 29.5 30 2 1 31 31 31 18 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 PRP86885.1 - 5.2e-27 94.0 7.3 0.0041 17.2 0.0 14.0 15 0 0 15 15 14 6 Flagellar-associated PapD-like Motile_Sperm PF00635.26 PRP86885.1 - 3.8e-23 81.4 44.7 0.29 11.0 0.0 19.7 20 0 0 20 20 19 6 MSP (Major sperm protein) domain DUF1573 PF07610.11 PRP86885.1 - 3.1e-18 65.6 47.9 0.69 10.0 0.0 23.8 29 1 0 29 29 29 5 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 PRP86885.1 - 1.1e-09 38.4 26.9 0.06 13.6 0.1 14.1 17 0 0 17 17 14 4 Transmembrane protein 131-like AAA_18 PF13238.6 PRP86885.1 - 7.8e-07 29.7 0.0 2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 PRP86885.1 - 0.0081 16.3 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate kinase Gal-bind_lectin PF00337.22 PRP86885.1 - 0.015 14.8 0.2 10 5.7 0.0 3.7 3 0 0 3 3 3 0 Galactoside-binding lectin AAA_28 PF13521.6 PRP86885.1 - 0.057 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PRP86885.1 - 0.083 13.3 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 PRP86885.1 - 0.09 13.2 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PRP86885.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 PRP86885.1 - 4.9 7.4 10.0 0.32 11.3 0.0 3.2 2 1 1 3 3 3 0 Hydin Adenylate kinase-like domain BBP1_C PF15272.6 PRP86885.1 - 7.7 6.3 9.4 8.2 6.2 7.0 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal LUC7 PF03194.15 PRP86887.1 - 9.9e-76 254.7 10.4 1.9e-75 253.8 10.4 1.5 1 0 0 1 1 1 1 LUC7 N_terminus Ins134_P3_kin PF05770.11 PRP86887.1 - 7.7e-44 149.6 0.0 2e-43 148.3 0.0 1.7 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain WD40 PF00400.32 PRP86887.1 - 6.1e-17 61.7 3.5 4.2e-05 24.2 0.8 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat FtsX PF02687.21 PRP86887.1 - 1.3e-13 51.3 24.2 2.8e-09 37.3 9.1 5.5 6 0 0 6 6 6 2 FtsX-like permease family ANAPC4_WD40 PF12894.7 PRP86887.1 - 4.8e-12 46.0 0.3 0.00079 19.7 0.0 5.2 3 2 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ins134_P3_kin_N PF17927.1 PRP86887.1 - 1.4e-09 38.2 0.0 3.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Nup160 PF11715.8 PRP86887.1 - 0.0069 15.1 1.0 0.35 9.5 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PRP38_assoc PF12871.7 PRP86887.1 - 0.06 14.0 29.1 0.015 15.9 18.8 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-ribbon_3 PF13248.6 PRP86888.1 - 3.7e-05 23.0 7.0 4.8e-05 22.6 7.0 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 PRP86888.1 - 0.00037 20.4 1.2 0.00038 20.4 1.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 PRP86888.1 - 0.00048 19.8 10.0 0.00065 19.3 10.0 1.2 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 PRP86888.1 - 0.0011 19.6 1.5 0.0011 19.6 1.5 1.1 1 0 0 1 1 1 1 zinc-ribbon family HypA PF01155.19 PRP86888.1 - 0.0036 17.3 1.2 0.0046 17.0 1.2 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-LITAF-like PF10601.9 PRP86888.1 - 0.0054 17.0 0.5 0.0068 16.7 0.5 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-C3HC4_3 PF13920.6 PRP86888.1 - 0.0069 16.2 2.6 0.0086 15.9 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NRDD PF13597.6 PRP86888.1 - 0.026 13.3 1.6 0.025 13.4 1.6 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase TFIIS_C PF01096.18 PRP86888.1 - 2.2 8.2 9.0 4.2 7.3 0.9 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Beta_helix PF13229.6 PRP86889.1 - 7.7e-27 94.1 174.2 5.9e-08 32.7 21.8 7.4 1 1 5 7 7 7 6 Right handed beta helix region NosD PF05048.13 PRP86889.1 - 9.6e-13 47.9 128.9 0.00013 21.3 7.9 6.8 1 1 5 6 6 6 4 Periplasmic copper-binding protein (NosD) CbeA_antitoxin PF06154.11 PRP86889.1 - 0.22 12.1 1.4 3.1 8.5 0.1 3.2 3 0 0 3 3 3 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A MIEAP PF16026.5 PRP86890.1 - 0.014 15.6 0.1 0.016 15.4 0.1 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein Med9 PF07544.13 PRP86892.1 - 0.00066 19.7 0.9 0.00066 19.7 0.9 2.1 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF349 PF03993.12 PRP86892.1 - 0.086 13.2 1.0 0.15 12.4 1.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF2680 PF10925.8 PRP86892.1 - 0.12 12.4 5.1 0.24 11.4 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Glyco_transf_8 PF01501.20 PRP86893.1 - 3.6e-06 26.7 0.1 0.00055 19.6 0.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 PRP86893.1 - 0.065 12.6 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative FSAP_sig_propep PF03032.15 PRP86893.1 - 0.22 11.6 4.4 0.4 10.7 4.4 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide SH3_1 PF00018.28 PRP86894.1 - 2.3e-11 43.1 0.6 4.1e-11 42.3 0.6 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP86894.1 - 1.5e-10 40.7 0.8 3.5e-10 39.6 0.8 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP86894.1 - 2.1e-10 40.1 0.0 3.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Rubis-subs-bind PF09273.11 PRP86895.1 - 5.7e-07 30.3 0.1 1.1e-06 29.4 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 PRP86895.1 - 0.00015 22.2 0.0 0.00038 20.9 0.0 1.7 1 1 0 1 1 1 1 SET domain PhaP_Bmeg PF09602.10 PRP86895.1 - 0.0045 17.0 0.2 0.24 11.3 0.0 2.5 3 0 0 3 3 3 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Carb_bind PF10645.9 PRP86898.1 - 0.0013 18.9 2.8 0.0013 18.9 2.8 3.4 2 1 1 3 3 3 2 Carbohydrate binding SIR2 PF02146.17 PRP86899.1 - 9.8e-29 100.5 0.0 3.3e-26 92.3 0.0 2.3 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 PRP86899.1 - 0.00063 19.5 0.0 0.81 9.4 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain COG2 PF06148.11 PRP86900.1 - 5.1e-32 110.8 2.0 5.1e-32 110.8 2.0 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 PRP86900.1 - 2.8e-22 79.5 4.7 3.1e-21 76.1 0.6 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 PRP86900.1 - 0.00031 20.8 4.7 0.00065 19.7 0.1 3.1 3 0 0 3 3 3 1 Vps51/Vps67 DUF1664 PF07889.12 PRP86900.1 - 0.19 11.8 9.2 0.44 10.6 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Pyrid_ox_like PF16242.5 PRP86902.1 - 5.5e-33 113.7 0.0 1.1e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 PRP86902.1 - 4.3e-07 30.0 0.0 7.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GTP_EFTU PF00009.27 PRP86903.1 - 1.4e-60 204.2 0.9 1.9e-60 203.7 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PRP86903.1 - 5.5e-34 116.6 0.0 6e-33 113.2 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 PRP86903.1 - 3.2e-21 75.2 0.0 6.4e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 PRP86903.1 - 7.9e-15 54.7 0.1 2.4e-14 53.2 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 PRP86903.1 - 1e-13 51.5 0.0 3.3e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PRP86903.1 - 0.013 15.6 0.1 0.036 14.2 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase RF3_C PF16658.5 PRP86903.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain TetR_C_25 PF17933.1 PRP86903.1 - 0.14 12.5 0.0 0.5 10.7 0.0 1.9 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain YihI PF04220.12 PRP86903.1 - 1.6 8.4 6.1 4.4 7.0 6.1 1.7 1 0 0 1 1 1 0 Der GTPase activator (YihI) Pkinase PF00069.25 PRP86904.1 - 8.3e-68 228.6 0.0 1.1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86904.1 - 5.9e-32 111.0 0.0 8.2e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP86904.1 - 5.2e-06 26.0 0.0 3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 PRP86904.1 - 6.8e-05 22.6 0.2 0.042 13.5 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PRP86904.1 - 0.00036 19.4 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP86904.1 - 0.00036 19.9 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP86904.1 - 0.005 16.8 0.0 0.018 15.0 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP86904.1 - 0.02 13.8 0.6 0.12 11.3 0.6 2.0 1 1 0 1 1 1 0 Haspin like kinase domain SAICAR_synt PF01259.18 PRP86905.1 - 2.4e-76 256.7 0.0 3.1e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Recep_L_domain PF01030.24 PRP86906.1 - 0.00022 21.3 16.8 0.31 11.2 0.0 6.3 3 1 3 6 6 6 2 Receptor L domain LRR_8 PF13855.6 PRP86906.1 - 1.8 8.4 7.4 8.8 6.2 0.1 4.6 4 0 0 4 4 4 0 Leucine rich repeat N2227 PF07942.12 PRP86907.1 - 1.9e-92 309.3 0.1 2.3e-92 309.0 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 PRP86907.1 - 0.012 16.4 0.0 0.044 14.5 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 PRP86908.1 - 0.0031 17.4 0.1 0.047 13.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain PIN_10 PF18478.1 PRP86908.1 - 0.15 12.3 0.8 0.34 11.1 0.0 2.0 2 0 0 2 2 2 0 PIN like domain Transket_pyr PF02779.24 PRP86909.1 - 3.1e-44 150.8 0.0 4.1e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PRP86909.1 - 1.2e-43 147.9 0.1 2.1e-43 147.1 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 PRP86909.1 - 0.0091 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF5586 PF17824.1 PRP86910.1 - 9.2e-05 21.7 0.5 0.00013 21.2 0.1 1.4 2 0 0 2 2 2 1 Family of unknown function (DUF5586) DUF5582 PF17819.1 PRP86910.1 - 0.0015 19.0 0.5 0.0031 18.0 0.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5582) Dpy-30 PF05186.13 PRP86910.1 - 0.028 14.1 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 Dpy-30 motif Pox_L5 PF04872.13 PRP86910.1 - 0.037 13.9 0.0 18 5.3 0.0 2.9 2 1 1 3 3 3 0 Poxvirus L5 protein family C2 PF00168.30 PRP86912.1 - 2.4e-05 24.6 0.0 5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF639 PF04842.12 PRP86912.1 - 0.0023 17.4 0.1 0.0047 16.4 0.1 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) Ank_4 PF13637.6 PRP86913.1 - 7.7e-15 55.1 1.9 1.4e-06 28.7 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP86913.1 - 5.1e-14 52.0 0.4 0.0006 20.2 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 PRP86913.1 - 4.9e-13 49.5 3.4 9.7e-09 35.7 1.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP86913.1 - 1.9e-09 37.6 0.3 0.032 14.6 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP86913.1 - 4.5e-06 26.6 1.3 0.7 10.7 0.1 4.6 3 1 1 4 4 4 2 Ankyrin repeat Kinesin PF00225.23 PRP86919.1 - 4e-109 364.6 0.4 4e-109 364.6 0.4 2.0 2 0 0 2 2 2 1 Kinesin motor domain FH2 PF02181.23 PRP86919.1 - 2.4e-82 277.0 9.2 2.4e-82 277.0 9.2 4.9 3 1 1 5 5 5 2 Formin Homology 2 Domain Microtub_bd PF16796.5 PRP86919.1 - 5.3e-25 88.1 0.1 5.3e-25 88.1 0.1 3.5 4 0 0 4 4 4 1 Microtubule binding Rootletin PF15035.6 PRP86919.1 - 0.13 12.3 51.9 2.9 7.9 22.0 4.0 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 PRP86919.1 - 2 8.7 19.2 11 6.3 1.0 5.4 3 1 1 4 4 4 0 Homeobox associated leucine zipper Filament PF00038.21 PRP86919.1 - 7.8 6.0 62.1 0.035 13.7 5.7 5.1 2 2 2 4 4 4 0 Intermediate filament protein Pkinase PF00069.25 PRP86920.1 - 1.5e-17 63.9 0.0 7.2e-16 58.3 0.0 2.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86920.1 - 1.1e-09 38.0 0.0 5.6e-09 35.7 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase PTPA PF03095.15 PRP86921.1 - 1.1e-122 409.3 0.0 1.3e-122 409.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Pribosyltran_N PF13793.6 PRP86922.1 - 1e-47 160.9 0.3 9e-47 157.8 0.0 2.5 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 PRP86922.1 - 4.5e-32 111.6 2.1 1.9e-26 93.3 0.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 PRP86922.1 - 2.7e-06 27.0 2.3 3.1e-05 23.5 2.4 2.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM2 PF07297.12 PRP86923.1 - 2.2e-19 69.5 9.1 2.4e-19 69.4 9.1 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 PRP86923.1 - 0.0043 17.0 10.0 0.0051 16.7 10.0 1.0 1 0 0 1 1 1 1 PIG-P ACOX PF01756.19 PRP86924.1 - 1.1e-15 57.7 0.3 2e-15 56.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PRP86924.1 - 2.4e-15 56.5 0.1 5e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 PRP86924.1 - 0.00074 20.1 0.1 0.0021 18.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 PRP86924.1 - 0.0039 17.4 0.1 0.0082 16.4 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FOP_dimer PF09398.10 PRP86925.1 - 1.1e-10 41.6 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 PRP86925.1 - 0.0017 17.4 0.2 0.0017 17.4 0.2 1.7 2 0 0 2 2 2 1 LisH LisH PF08513.11 PRP86925.1 - 0.0057 16.6 0.4 0.0099 15.8 0.4 1.4 1 0 0 1 1 1 1 LisH Ig_C17orf99 PF17736.1 PRP86925.1 - 0.082 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 C17orf99 Ig domain ANAPC3 PF12895.7 PRP86926.1 - 4.9e-08 33.1 23.2 0.0021 18.3 1.9 5.1 5 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP86926.1 - 4.8e-07 30.2 16.4 0.00099 19.6 0.3 5.7 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 PRP86926.1 - 0.00036 20.4 22.0 0.3 11.3 0.1 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP86926.1 - 0.00054 20.6 0.2 15 6.8 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP86926.1 - 0.026 15.1 9.6 3.2 8.6 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP86926.1 - 0.057 13.5 0.8 5.7 7.1 0.4 3.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 PRP86926.1 - 0.095 13.0 2.1 4.7 7.7 0.1 4.1 5 0 0 5 5 5 0 PPR repeat TPR_9 PF13371.6 PRP86926.1 - 0.14 12.3 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 PRP86926.1 - 0.15 11.4 6.6 0.89 8.9 4.1 2.8 2 1 0 2 2 2 0 Coatomer epsilon subunit PH PF00169.29 PRP86927.1 - 1.4e-09 38.4 0.0 2.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 PH domain CH PF00307.31 PRP86927.1 - 3e-09 37.0 0.0 6.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF1394 PF07159.12 PRP86928.1 - 1e-108 363.2 0.7 1.9e-108 362.3 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) RhoGEF PF00621.20 PRP86928.1 - 4.4e-41 141.1 0.9 1e-40 139.9 0.3 2.0 2 0 0 2 2 2 1 RhoGEF domain Ank_5 PF13857.6 PRP86928.1 - 1.3e-12 47.7 0.1 2e-05 24.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP86928.1 - 2.9e-11 43.7 0.0 0.0037 17.8 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86928.1 - 2.1e-10 41.0 0.0 0.00087 19.8 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 PRP86928.1 - 2e-05 25.0 0.1 8.8e-05 23.0 0.0 2.2 2 0 0 2 2 1 1 PH domain Ank_3 PF13606.6 PRP86928.1 - 5.7e-05 23.2 0.3 2.7 8.9 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat PH_13 PF16652.5 PRP86928.1 - 0.00087 19.1 0.2 0.0075 16.1 0.2 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain F-box-like PF12937.7 PRP86928.1 - 0.0014 18.5 0.2 0.0065 16.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like Ank PF00023.30 PRP86928.1 - 0.0016 18.8 0.8 9.3 6.9 0.0 4.4 4 1 0 4 4 3 1 Ankyrin repeat IQ_SEC7_PH PF16453.5 PRP86928.1 - 0.0077 16.2 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 PH domain F-box PF00646.33 PRP86928.1 - 0.031 14.2 0.1 0.77 9.7 0.0 2.7 2 0 0 2 2 2 0 F-box domain Complex1_LYR PF05347.15 PRP86929.1 - 4.5e-12 45.8 0.7 4.5e-12 45.8 0.7 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 PRP86929.1 - 0.036 14.7 0.2 0.14 12.8 0.2 2.0 1 0 0 1 1 1 0 Complex1_LYR-like Complex1_LYR_2 PF13233.6 PRP86929.1 - 0.068 13.9 0.7 0.068 13.9 0.7 2.1 2 1 0 2 2 2 0 Complex1_LYR-like Pkinase PF00069.25 PRP86930.1 - 2.2e-54 184.6 0.0 4.1e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86930.1 - 4.3e-48 163.9 0.0 7e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 PRP86930.1 - 9.5e-20 71.0 0.1 5.6e-10 39.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP86930.1 - 3.8e-12 46.5 0.8 0.0067 17.0 0.0 4.9 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP86930.1 - 1.9e-11 43.8 1.8 0.0036 17.7 0.0 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 PRP86930.1 - 1.1e-10 40.8 0.3 0.034 14.7 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PRP86930.1 - 4.1e-07 30.1 0.1 0.0025 18.1 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 PRP86930.1 - 2.8e-05 23.3 0.4 0.00018 20.5 0.0 2.4 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 PRP86930.1 - 0.00018 21.2 0.1 0.052 13.2 0.0 3.0 2 1 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PRP86930.1 - 0.036 14.0 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Homeodomain PF00046.29 PRP86931.1 - 6.2e-57 189.3 13.2 3.6e-11 42.7 0.1 6.2 6 0 0 6 6 6 5 Homeodomain Homeobox_KN PF05920.11 PRP86931.1 - 6.2e-19 67.6 3.9 0.0036 17.2 0.0 6.7 6 0 0 6 6 6 3 Homeobox KN domain Homez PF11569.8 PRP86931.1 - 3e-08 33.0 6.1 7.8 6.1 0.1 6.4 6 0 0 6 6 6 2 Homeodomain leucine-zipper encoding, Homez Phage_terminase PF10668.9 PRP86931.1 - 4e-06 26.7 0.9 2.3 8.3 0.0 4.7 4 0 0 4 4 4 2 Phage terminase small subunit HTH_23 PF13384.6 PRP86931.1 - 3e-05 23.7 0.0 5.1 7.0 0.0 4.4 4 0 0 4 4 4 2 Homeodomain-like domain TetR_C_4 PF08359.11 PRP86931.1 - 0.00019 21.6 0.1 0.97 9.6 0.0 2.4 2 0 0 2 2 2 2 YsiA-like protein, C-terminal region HTH_Tnp_ISL3 PF13542.6 PRP86931.1 - 0.00045 19.6 0.0 3.3 7.2 0.0 3.7 4 0 0 4 4 4 2 Helix-turn-helix domain of transposase family ISL3 DUF167 PF02594.16 PRP86931.1 - 0.0043 17.1 0.0 6 7.1 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 WRW PF10206.9 PRP86931.1 - 0.0052 17.1 1.6 24 5.4 0.0 4.1 4 0 0 4 4 4 0 Mitochondrial F1F0-ATP synthase, subunit f SeqA PF03925.13 PRP86931.1 - 0.0058 16.6 0.4 5.1 7.1 0.1 2.5 2 0 0 2 2 2 2 SeqA protein C-terminal domain AlkA_N PF06029.11 PRP86931.1 - 0.0066 16.7 0.0 6.2 7.1 0.0 2.5 2 0 0 2 2 2 2 AlkA N-terminal domain IF2_N PF04760.15 PRP86931.1 - 0.0066 16.2 0.0 9.9 6.1 0.0 3.3 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region PPP5 PF08321.12 PRP86931.1 - 0.0095 16.2 1.0 7.4 6.9 0.1 2.8 2 0 0 2 2 2 2 PPP5 TPR repeat region UPF0154 PF03672.13 PRP86931.1 - 0.016 15.2 0.7 8.5 6.5 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF1510 PF07423.11 PRP86931.1 - 0.017 15.3 0.0 14 5.9 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) GerE PF00196.19 PRP86931.1 - 0.018 14.6 0.3 9.8 5.8 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family JHD PF17811.1 PRP86931.1 - 0.018 15.5 0.4 13 6.4 0.2 3.3 2 1 0 2 2 2 0 Jumonji helical domain HTH_OrfB_IS605 PF12323.8 PRP86931.1 - 0.023 14.2 5.9 3.4 7.2 0.0 4.2 6 0 0 6 6 6 0 Helix-turn-helix domain rve_2 PF13333.6 PRP86931.1 - 0.031 14.4 1.2 24 5.2 0.0 3.8 4 0 0 4 4 4 0 Integrase core domain Sigma70_r4_2 PF08281.12 PRP86931.1 - 0.047 13.4 0.0 15 5.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_28 PF13518.6 PRP86931.1 - 0.09 12.9 0.0 31 4.8 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Pyrophosphatase PF00719.19 PRP86931.1 - 8.5 6.2 7.5 34 4.2 0.1 3.7 4 0 0 4 4 4 0 Inorganic pyrophosphatase Ribonuc_P_40 PF08584.11 PRP86932.1 - 2e-46 158.6 0.0 3.1e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit BUD22 PF09073.10 PRP86932.1 - 0.0054 16.1 7.1 0.0069 15.8 7.1 1.1 1 0 0 1 1 1 1 BUD22 Eapp_C PF10238.9 PRP86932.1 - 0.031 14.3 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein CobT PF06213.12 PRP86932.1 - 0.038 13.4 6.1 0.051 13.0 6.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 PRP86932.1 - 0.049 13.4 11.1 0.079 12.8 11.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prothymosin PF03247.14 PRP86932.1 - 0.099 13.1 21.9 0.15 12.5 21.9 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family FAM176 PF14851.6 PRP86932.1 - 0.11 12.1 4.2 0.18 11.5 4.2 1.3 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.18 PRP86932.1 - 0.12 12.3 5.6 0.16 11.9 5.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Presenilin PF01080.17 PRP86932.1 - 0.27 9.9 1.3 0.35 9.6 1.3 1.1 1 0 0 1 1 1 0 Presenilin Afi1 PF07792.12 PRP86932.1 - 0.5 10.9 5.6 0.81 10.2 5.6 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3464 PF11947.8 PRP86932.1 - 0.53 10.0 2.5 0.89 9.3 2.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 RasGAP PF00616.19 PRP86932.1 - 0.55 9.9 3.6 0.92 9.2 3.6 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Connexin PF00029.19 PRP86932.1 - 0.65 9.7 2.7 0.91 9.2 2.7 1.2 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 PRP86932.1 - 0.69 8.8 2.0 0.93 8.4 2.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MscS_TM PF12794.7 PRP86932.1 - 0.7 8.7 1.2 0.95 8.3 1.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 NPR3 PF03666.13 PRP86932.1 - 1.4 7.7 4.8 1.9 7.2 4.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 PRP86932.1 - 1.9 7.3 7.1 2.6 6.8 7.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPN2_C PF18004.1 PRP86932.1 - 2.7 7.9 11.8 4.7 7.1 11.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP1_TM PF14812.6 PRP86932.1 - 2.9 8.3 10.8 5.9 7.3 10.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 PRP86932.1 - 5.5 5.1 15.3 7.3 4.7 15.3 1.0 1 0 0 1 1 1 0 Nop14-like family FancD2 PF14631.6 PRP86932.1 - 5.6 4.2 4.5 7.2 3.9 4.5 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF4820 PF16091.5 PRP86932.1 - 5.8 6.2 8.4 10 5.4 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RNA_pol_3_Rpc31 PF11705.8 PRP86932.1 - 6.2 7.0 16.7 9.2 6.4 16.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 UQ_con PF00179.26 PRP86933.1 - 3.3e-52 175.9 0.0 5.2e-52 175.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PRP86933.1 - 0.011 15.9 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 PRP86933.1 - 0.031 14.0 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Lyase_8 PF02278.18 PRP86934.1 - 2e-56 191.4 2.0 2e-56 191.4 2.0 3.5 4 0 0 4 4 4 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 PRP86934.1 - 2.9e-19 69.1 0.1 5.6e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 PRP86934.1 - 3e-09 37.2 0.3 3e-09 37.2 0.3 3.3 3 0 0 3 3 3 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain MORN PF02493.20 PRP86936.1 - 5.5e-19 66.9 42.0 3.3e-06 26.7 0.9 7.2 8 0 0 8 8 8 4 MORN repeat Ribosomal_60s PF00428.19 PRP86936.1 - 4 8.1 10.6 8.2 7.1 0.2 3.8 3 1 0 3 3 3 0 60s Acidic ribosomal protein Pkinase PF00069.25 PRP86937.1 - 3.9e-52 177.2 0.0 6.2e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86937.1 - 3.9e-27 95.2 0.0 8.6e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP86937.1 - 3.9e-05 23.7 0.0 0.00026 21.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP86937.1 - 0.00036 19.9 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SLED PF12140.8 PRP86937.1 - 0.073 13.6 0.2 0.73 10.4 0.0 2.8 3 0 0 3 3 3 0 SLED domain Metallophos PF00149.28 PRP86938.1 - 1.3e-19 71.5 1.5 2e-19 70.9 1.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PRP86938.1 - 5.4e-18 65.3 1.4 1.2e-17 64.2 0.8 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 PRP86938.1 - 8.5e-18 65.0 4.8 1.3e-17 64.4 2.2 2.5 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD_N PF16655.5 PRP86938.1 - 0.0052 17.3 0.1 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Transthyretin PF00576.21 PRP86939.1 - 3.1e-36 124.4 0.0 3.6e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family TFIID-18kDa PF02269.16 PRP86940.1 - 3.1e-19 68.8 1.3 4.4e-19 68.3 1.3 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Sec16_C PF12931.7 PRP86941.1 - 8.6e-40 137.3 0.0 1.9e-39 136.1 0.0 1.5 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 PRP86941.1 - 4.6e-22 78.8 0.0 1e-21 77.7 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region AA_permease PF00324.21 PRP86942.1 - 3.9e-141 470.9 40.1 4.8e-141 470.6 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 PRP86942.1 - 7.7e-40 137.0 43.7 9.3e-40 136.7 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease MBF1 PF08523.10 PRP86943.1 - 6.2e-17 61.8 3.1 6.2e-17 61.8 3.1 2.0 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 PRP86943.1 - 1.1e-14 54.2 0.4 2.5e-14 53.1 0.4 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 PRP86943.1 - 2.3e-07 31.0 0.0 6.7e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 PRP86943.1 - 6.7e-05 22.8 0.2 0.00017 21.5 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.6 PRP86943.1 - 0.0069 16.2 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HECT PF00632.25 PRP86944.1 - 8.5e-98 327.6 0.6 1.6e-97 326.7 0.1 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 PRP86944.1 - 7.4e-45 153.5 6.9 1.5e-39 136.0 0.0 4.9 4 1 1 5 5 5 2 Domain of Unknown Function (DUF913) UBM PF14377.6 PRP86944.1 - 5.3e-24 82.9 19.2 2.9e-11 42.4 2.8 4.3 3 1 1 4 4 4 3 Ubiquitin binding region DUF908 PF06012.12 PRP86944.1 - 1.4e-16 60.9 0.0 1.4e-16 60.9 0.0 4.9 6 1 0 7 7 7 2 Domain of Unknown Function (DUF908) DUF5610 PF18433.1 PRP86944.1 - 0.026 15.0 0.4 3.4 8.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5610) UBA PF00627.31 PRP86944.1 - 0.082 12.8 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain BLOC1_2 PF10046.9 PRP86944.1 - 0.16 12.3 1.0 0.72 10.2 0.2 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HIG_1_N PF04588.13 PRP86945.1 - 1.2e-05 25.4 0.1 1.8e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PsbJ PF01788.17 PRP86945.1 - 1.5 8.8 5.1 3.9 7.4 0.1 2.1 2 0 0 2 2 2 0 PsbJ GAF PF01590.26 PRP86946.1 - 2.5e-07 31.4 0.0 4.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 PRP86946.1 - 0.0015 18.8 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 GAF domain RPA_interact_N PF14766.6 PRP86946.1 - 0.45 10.2 4.8 0.17 11.6 1.0 2.1 2 0 0 2 2 2 0 Replication protein A interacting N-terminal CDP-OH_P_transf PF01066.21 PRP86947.1 - 1.4e-18 67.4 0.2 1.4e-18 67.4 0.2 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ank_4 PF13637.6 PRP86948.1 - 4.2e-11 43.2 1.1 0.026 15.1 0.0 5.3 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86948.1 - 1.1e-08 35.5 0.0 0.0011 19.5 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) F-box PF00646.33 PRP86948.1 - 0.00012 21.9 0.1 0.00029 20.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP86948.1 - 0.00025 20.9 0.1 0.00071 19.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like Ank_3 PF13606.6 PRP86948.1 - 0.00064 20.0 0.0 53 4.9 0.0 5.3 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 PRP86948.1 - 0.00098 19.4 0.1 29 5.1 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) S_locus_glycop PF00954.20 PRP86949.1 - 0.0043 17.6 0.5 0.02 15.4 0.1 2.0 2 0 0 2 2 2 1 S-locus glycoprotein domain MASE4 PF17158.4 PRP86949.1 - 0.16 11.2 1.6 0.23 10.7 1.6 1.2 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain SNF2_N PF00176.23 PRP86950.1 - 6.7e-23 81.0 0.3 1.9e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 PRP86950.1 - 1.9e-12 47.2 0.0 1.9e-12 47.2 0.0 3.5 2 1 1 3 3 3 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 PRP86950.1 - 1.2e-07 32.1 0.2 4.8e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PRP86950.1 - 0.033 13.4 0.1 0.033 13.4 0.1 2.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 PRP86950.1 - 0.88 9.6 19.1 0.0086 16.0 10.0 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 PRP86950.1 - 4.6 7.2 9.9 20 5.1 9.9 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acyl-CoA_dh_N PF02771.16 PRP86951.1 - 5.5e-29 101.1 0.1 9.8e-29 100.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 PRP86951.1 - 8.2e-27 94.3 0.1 1.4e-26 93.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PRP86951.1 - 1e-20 73.7 0.0 2e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PRP86951.1 - 4.3e-05 23.8 0.1 8.1e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Usp PF00582.26 PRP86952.1 - 1.6e-15 57.8 0.4 4.9e-15 56.3 0.4 1.8 1 1 0 1 1 1 1 Universal stress protein family Carb_bind PF10645.9 PRP86953.1 - 0.003 17.7 4.3 0.003 17.7 4.3 4.7 3 1 1 4 4 4 2 Carbohydrate binding NUDE_C PF04880.13 PRP86953.1 - 9.2 6.7 6.9 15 6.1 6.9 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Steroid_dh PF02544.16 PRP86954.1 - 4.4e-38 130.6 7.5 2.1e-37 128.4 7.5 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 PRP86954.1 - 7e-06 25.7 0.2 7e-06 25.7 0.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) DUF3169 PF11368.8 PRP86954.1 - 0.035 13.6 1.7 0.043 13.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4282 PF14110.6 PRP86954.1 - 6 7.7 8.1 8.5 7.2 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) zf-NADH-PPase PF09297.11 PRP86955.1 - 0.0079 15.8 1.5 0.72 9.6 0.1 2.4 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain Anti-TRAP PF15777.5 PRP86955.1 - 0.051 13.6 0.3 0.096 12.7 0.3 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein I_LWEQ PF01608.17 PRP86956.1 - 2.4e-27 96.1 3.3 2.4e-27 96.1 3.3 5.8 3 2 1 5 5 5 1 I/LWEQ domain Arrestin_C PF02752.22 PRP86956.1 - 2.7e-17 63.5 5.3 3.4e-10 40.5 0.1 3.4 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PRP86956.1 - 1.2e-13 51.4 0.0 4.9e-13 49.4 0.0 2.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 PRP86956.1 - 0.0085 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like SesA PF17107.5 PRP86956.1 - 0.018 15.2 1.1 0.077 13.2 1.1 2.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3294 PF07957.11 PRP86956.1 - 0.044 13.5 3.0 0.12 12.1 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) NAD_Gly3P_dh_N PF01210.23 PRP86956.1 - 0.046 13.7 1.2 0.13 12.2 0.2 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PIEZO PF15917.5 PRP86956.1 - 0.07 12.6 0.8 0.16 11.4 0.8 1.5 1 0 0 1 1 1 0 Piezo DUF1993 PF09351.10 PRP86956.1 - 0.18 11.9 2.5 0.47 10.6 0.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF406 PF04175.12 PRP86956.1 - 0.32 11.5 0.0 0.32 11.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF406) ThiJ_like PF17124.5 PRP86957.1 - 2.8e-41 141.4 0.0 4.4e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 PRP86957.1 - 3.9e-09 36.5 0.0 3.8e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family WES_acyltransf PF03007.16 PRP86957.1 - 2.3e-08 34.1 0.0 3.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.12 PRP86957.1 - 0.0018 16.9 0.1 0.0078 14.8 0.1 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase SNO PF01174.19 PRP86957.1 - 0.06 13.2 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 SNO glutamine amidotransferase family Carb_bind PF10645.9 PRP86957.1 - 0.071 13.3 18.4 0.027 14.7 4.3 2.9 2 1 1 3 3 3 0 Carbohydrate binding Homeodomain PF00046.29 PRP86958.1 - 2.9e-16 59.1 7.4 4.5e-16 58.4 7.4 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP86958.1 - 5.3e-09 35.8 0.5 1.2e-08 34.7 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain MRP-63 PF14978.6 PRP86958.1 - 0.039 14.6 1.3 0.057 14.0 1.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 NmrA PF05368.13 PRP86959.1 - 6.4e-21 75.0 0.0 1.3e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP86959.1 - 5.9e-20 71.9 0.1 9.3e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding EGF_2 PF07974.13 PRP86959.1 - 1.1e-11 44.9 69.5 0.00029 21.1 15.5 4.5 4 0 0 4 4 4 4 EGF-like domain Epimerase PF01370.21 PRP86959.1 - 0.0058 16.1 0.0 0.035 13.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 PRP86959.1 - 0.0084 16.5 0.1 0.026 15.0 0.1 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 PRP86959.1 - 0.011 15.9 0.1 0.023 14.8 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Laminin_EGF PF00053.24 PRP86959.1 - 0.046 13.9 64.6 0.22 11.7 11.6 4.7 2 1 3 5 5 5 0 Laminin EGF domain EGF PF00008.27 PRP86959.1 - 1.8 8.9 58.4 0.087 13.2 11.5 4.5 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.7 PRP86959.1 - 8.8 7.1 54.7 0.18 12.5 8.4 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF GAS PF13851.6 PRP86960.1 - 1.2e-07 31.3 3.7 2.8e-07 30.1 3.7 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FlxA PF14282.6 PRP86960.1 - 2.7e-06 27.3 4.2 4.8e-06 26.5 2.5 2.2 2 0 0 2 2 2 1 FlxA-like protein Rootletin PF15035.6 PRP86960.1 - 0.0002 21.4 6.7 0.03 14.3 0.2 2.5 1 1 1 2 2 2 2 Ciliary rootlet component, centrosome cohesion Uso1_p115_C PF04871.13 PRP86960.1 - 0.00036 20.9 3.1 0.00036 20.9 3.1 2.9 3 0 0 3 3 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 PRP86960.1 - 0.0008 19.1 1.6 0.33 10.8 0.0 2.6 2 0 0 2 2 2 1 Septum formation initiator SOGA PF11365.8 PRP86960.1 - 0.0041 18.2 2.7 0.014 16.5 2.7 1.9 1 0 0 1 1 1 1 Protein SOGA DMPK_coil PF08826.10 PRP86960.1 - 0.0043 17.1 3.0 0.6 10.3 0.1 2.5 2 0 0 2 2 2 1 DMPK coiled coil domain like FemAB PF02388.16 PRP86960.1 - 0.0059 15.5 2.3 0.0088 15.0 2.3 1.1 1 0 0 1 1 1 1 FemAB family DHR10 PF18595.1 PRP86960.1 - 0.006 16.6 8.4 0.015 15.4 8.4 1.6 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain RasGAP_C PF03836.15 PRP86960.1 - 0.0079 16.3 3.5 0.018 15.2 3.4 1.6 1 1 0 1 1 1 1 RasGAP C-terminus AAA_13 PF13166.6 PRP86960.1 - 0.0081 14.9 3.4 0.41 9.2 1.9 2.1 2 0 0 2 2 2 1 AAA domain bZIP_1 PF00170.21 PRP86960.1 - 0.0084 16.2 6.3 0.74 10.0 0.5 2.6 2 0 0 2 2 2 2 bZIP transcription factor TSC22 PF01166.18 PRP86960.1 - 0.014 15.7 4.3 2 8.8 0.2 3.0 1 1 1 2 2 2 0 TSC-22/dip/bun family HemX PF04375.14 PRP86960.1 - 0.019 14.3 1.0 0.028 13.7 1.0 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ATG16 PF08614.11 PRP86960.1 - 0.022 15.0 5.3 0.022 15.0 5.3 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 PRP86960.1 - 0.03 14.4 4.9 1.4 9.1 1.7 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation Plant_NMP1 PF06694.11 PRP86960.1 - 0.036 13.2 0.2 0.036 13.2 0.2 1.5 2 0 0 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) Cnn_1N PF07989.11 PRP86960.1 - 0.038 14.2 7.3 0.75 10.0 0.2 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 FapA PF03961.13 PRP86960.1 - 0.055 12.1 1.8 0.083 11.5 1.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Phage_GPO PF05929.11 PRP86960.1 - 0.066 12.8 1.6 0.11 12.0 1.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Atg14 PF10186.9 PRP86960.1 - 0.071 12.2 8.4 0.15 11.1 8.4 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF641 PF04859.12 PRP86960.1 - 0.12 12.7 2.2 0.25 11.7 2.2 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3450 PF11932.8 PRP86960.1 - 0.14 11.5 2.5 0.24 10.7 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) YabA PF06156.13 PRP86960.1 - 0.14 12.8 5.3 1.3 9.7 5.2 2.4 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 PRP86960.1 - 0.14 12.6 8.2 0.51 10.8 8.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 PRP86960.1 - 0.16 12.4 4.1 0.37 11.2 4.1 1.6 1 0 0 1 1 1 0 Snapin/Pallidin GIT_CC PF16559.5 PRP86960.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.2 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Syntaxin PF00804.25 PRP86960.1 - 0.25 11.0 4.8 0.11 12.2 1.8 1.8 2 0 0 2 2 2 0 Syntaxin SpecificRecomb PF10136.9 PRP86960.1 - 0.25 9.6 0.5 0.32 9.2 0.5 1.1 1 0 0 1 1 1 0 Site-specific recombinase Spc24 PF08286.11 PRP86960.1 - 0.25 11.6 7.1 1.8 8.9 1.3 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Swi5 PF07061.11 PRP86960.1 - 0.37 10.9 6.2 0.79 9.9 0.9 2.4 1 1 1 2 2 2 0 Swi5 KASH_CCD PF14662.6 PRP86960.1 - 0.38 10.6 11.4 0.14 12.0 7.0 2.3 2 1 1 3 3 2 0 Coiled-coil region of CCDC155 or KASH SKA2 PF16740.5 PRP86960.1 - 0.39 10.5 4.6 0.23 11.2 2.6 1.7 2 0 0 2 2 1 0 Spindle and kinetochore-associated protein 2 Ax_dynein_light PF10211.9 PRP86960.1 - 0.55 10.2 8.2 0.66 9.9 6.2 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain CENP-H PF05837.12 PRP86960.1 - 0.65 10.4 4.7 1.6 9.1 4.7 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Spc7 PF08317.11 PRP86960.1 - 0.7 8.7 8.1 0.24 10.3 4.7 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 PRP86960.1 - 2 9.1 5.7 30 5.3 1.4 2.8 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.6 PRP86960.1 - 2.1 7.7 4.7 3 7.1 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Hsk3 PF08227.11 PRP86960.1 - 8.7 6.8 8.4 33 5.0 0.3 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like RasGAP_C PF03836.15 PRP86961.1 - 0.0031 17.7 1.1 0.0057 16.8 1.1 1.5 1 1 0 1 1 1 1 RasGAP C-terminus SesA PF17107.5 PRP86961.1 - 0.094 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases YabA PF06156.13 PRP86961.1 - 0.44 11.2 3.8 1.3 9.7 3.8 1.9 1 1 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 PRP86961.1 - 0.93 8.8 5.9 1.2 8.4 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AATF-Che1 PF13339.6 PRP86961.1 - 1.2 9.8 7.3 2.4 8.8 7.3 1.5 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Zip PF02535.22 PRP86961.1 - 1.4 8.1 5.5 1.9 7.6 5.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 PRP86961.1 - 1.9 6.3 4.9 2 6.2 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_phi PF04931.13 PRP86961.1 - 3.9 5.4 9.2 5.4 5.0 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi ZapB PF06005.12 PRP86961.1 - 8.3 6.9 11.1 0.32 11.5 2.3 2.5 2 0 0 2 2 2 0 Cell division protein ZapB GFO_IDH_MocA PF01408.22 PRP86962.1 - 4.3e-23 82.4 0.0 6.9e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PRP86962.1 - 0.0015 18.5 0.0 0.0049 16.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 PRP86963.1 - 1.7e-26 93.0 63.8 2.3e-19 69.5 43.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Ras PF00071.22 PRP86963.1 - 5.1e-25 87.9 0.0 8e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP86963.1 - 3.3e-06 27.3 0.0 9.7e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Virulence_fact PF13769.6 PRP86963.1 - 0.044 14.0 0.4 0.12 12.6 0.1 1.8 2 0 0 2 2 2 0 Virulence factor X8 PF07983.13 PRP86964.1 - 9.1e-50 167.3 48.1 2.2e-08 34.7 2.1 6.6 6 0 0 6 6 6 6 X8 domain Glyco_hydro_17 PF00332.18 PRP86964.1 - 4.8e-05 23.1 2.1 0.0001 22.0 0.7 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF2989 PF11207.8 PRP86964.1 - 0.0037 17.1 6.1 3.3 7.4 0.0 5.5 7 0 0 7 7 7 1 Protein of unknown function (DUF2989) DUF226 PF02890.14 PRP86964.1 - 0.3 11.1 2.0 12 6.0 0.0 3.2 4 0 0 4 4 4 0 Borrelia family of unknown function DUF226 Pkinase_Tyr PF07714.17 PRP86965.1 - 1.8e-76 256.8 0.0 4.1e-76 255.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP86965.1 - 2.6e-54 184.3 0.0 4.4e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP86965.1 - 1.1e-32 111.6 76.0 2.9e-10 39.8 6.8 12.2 7 3 6 14 14 14 10 Leucine rich repeat LRR_4 PF12799.7 PRP86965.1 - 5.7e-32 109.2 77.3 0.00056 20.2 1.1 14.9 7 3 8 17 17 17 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP86965.1 - 2.1e-07 30.6 16.2 0.16 11.5 0.7 6.8 4 1 3 7 7 7 4 Leucine-rich repeat LRR_1 PF00560.33 PRP86965.1 - 0.00074 19.7 57.7 5.6 7.9 0.2 18.3 17 4 0 17 17 17 2 Leucine Rich Repeat Kdo PF06293.14 PRP86965.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP86965.1 - 0.0025 16.7 0.0 0.0041 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP86965.1 - 0.056 12.4 0.1 0.33 9.9 0.1 2.2 1 1 0 1 1 1 0 Haspin like kinase domain SKG6 PF08693.10 PRP86965.1 - 0.081 12.3 5.0 0.033 13.6 1.4 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Phe_tRNA-synt_N PF02912.18 PRP86965.1 - 0.11 12.4 0.0 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain RabGAP-TBC PF00566.18 PRP86967.1 - 1.3e-41 142.7 4.4 1.9e-41 142.1 4.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4796 PF16044.5 PRP86967.1 - 0.072 12.7 1.2 0.2 11.3 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4796) SelB-wing_3 PF09107.11 PRP86967.1 - 0.11 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix TetR_C_9 PF14514.6 PRP86967.1 - 0.12 12.5 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SRP1_TIP1 PF00660.17 PRP86967.1 - 0.15 12.1 0.3 0.8 9.8 0.2 2.2 2 0 0 2 2 2 0 Seripauperin and TIP1 family HA PF03457.14 PRP86970.1 - 8.2e-36 122.2 15.2 1.9e-13 50.5 2.3 3.3 3 0 0 3 3 3 3 Helicase associated domain Cnn_1N PF07989.11 PRP86971.1 - 2.4e-07 30.8 2.6 2.4e-07 30.8 2.6 8.9 5 3 2 7 7 7 1 Centrosomin N-terminal motif 1 Ribosomal_L6e PF01159.19 PRP86971.1 - 0.049 14.2 0.3 0.049 14.2 0.3 5.3 4 1 1 5 5 5 0 Ribosomal protein L6e CRS1_YhbY PF01985.21 PRP86971.1 - 7.1 6.9 10.6 8.6 6.6 1.9 3.9 3 0 0 3 3 3 0 CRS1 / YhbY (CRM) domain MULE PF10551.9 PRP86972.1 - 0.0083 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Histone PF00125.24 PRP86973.1 - 2.3e-51 173.6 2.8 3e-51 173.2 2.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PRP86973.1 - 0.00024 21.7 1.6 0.00045 20.8 1.6 1.5 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 PRP86973.1 - 0.00032 20.8 0.1 0.00067 19.8 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PRP86973.1 - 0.001 19.4 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 PRP86973.1 - 0.003 17.6 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 PRP86973.1 - 0.025 14.9 0.6 0.041 14.2 0.1 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RhoGAP PF00620.27 PRP86975.1 - 1.4e-28 99.7 3.2 4.8e-13 49.2 0.0 3.8 3 1 0 3 3 3 2 RhoGAP domain MMPL PF03176.15 PRP86979.1 - 6.8 5.5 6.3 1.9 7.3 2.2 2.1 2 1 0 2 2 2 0 MMPL family NmrA PF05368.13 PRP86980.1 - 7.3e-23 81.3 0.1 9.1e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP86980.1 - 1e-20 74.4 0.1 1.8e-20 73.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 PRP86980.1 - 2.3e-06 27.9 0.0 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 PRP86980.1 - 6.5e-05 22.5 0.0 0.0028 17.2 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 PRP86980.1 - 0.00079 19.9 0.1 0.0017 18.8 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 PRP86980.1 - 0.00081 19.5 0.4 0.002 18.2 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 PRP86980.1 - 0.058 12.4 0.0 0.14 11.2 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GFO_IDH_MocA PF01408.22 PRP86980.1 - 0.12 13.3 0.0 0.25 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold EGF_2 PF07974.13 PRP86981.1 - 2.7e-12 46.8 69.5 0.0002 21.6 15.5 4.5 4 0 0 4 4 4 4 EGF-like domain Laminin_EGF PF00053.24 PRP86981.1 - 0.0056 16.8 63.7 0.14 12.4 11.4 4.7 2 1 3 5 5 5 4 Laminin EGF domain EGF PF00008.27 PRP86981.1 - 0.45 10.9 58.4 0.061 13.6 11.5 4.5 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.7 PRP86981.1 - 2.1 9.1 54.7 0.13 13.0 8.4 4.7 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 PRP86981.1 - 7.3 6.8 48.5 0.34 11.0 3.0 4.1 4 0 0 4 4 4 0 Tenascin EGF domain Homeodomain PF00046.29 PRP86982.1 - 6.6e-16 57.9 7.4 6.6e-16 57.9 7.4 1.7 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP86982.1 - 7.1e-09 35.4 0.5 1.6e-08 34.3 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain MRP-63 PF14978.6 PRP86982.1 - 0.053 14.1 1.4 0.091 13.4 1.4 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 ThiJ_like PF17124.5 PRP86983.1 - 2.8e-41 141.4 0.0 4.4e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 PRP86983.1 - 3.9e-09 36.5 0.0 3.8e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 DJ-1/PfpI family WES_acyltransf PF03007.16 PRP86983.1 - 2.3e-08 34.1 0.0 3.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.12 PRP86983.1 - 0.0018 16.9 0.1 0.0078 14.8 0.1 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase SNO PF01174.19 PRP86983.1 - 0.06 13.2 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 SNO glutamine amidotransferase family Carb_bind PF10645.9 PRP86983.1 - 0.071 13.3 18.4 0.027 14.7 4.3 2.9 2 1 1 3 3 3 0 Carbohydrate binding I_LWEQ PF01608.17 PRP86984.1 - 2.4e-27 96.1 3.3 2.4e-27 96.1 3.3 5.8 3 2 1 5 5 5 1 I/LWEQ domain Arrestin_C PF02752.22 PRP86984.1 - 2.7e-17 63.5 5.3 3.4e-10 40.5 0.1 3.4 4 0 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PRP86984.1 - 1.2e-13 51.4 0.0 4.9e-13 49.4 0.0 2.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 PRP86984.1 - 0.0085 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like SesA PF17107.5 PRP86984.1 - 0.018 15.2 1.1 0.077 13.2 1.1 2.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3294 PF07957.11 PRP86984.1 - 0.044 13.5 3.0 0.12 12.1 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) NAD_Gly3P_dh_N PF01210.23 PRP86984.1 - 0.046 13.7 1.2 0.13 12.2 0.2 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PIEZO PF15917.5 PRP86984.1 - 0.07 12.6 0.8 0.16 11.4 0.8 1.5 1 0 0 1 1 1 0 Piezo DUF1993 PF09351.10 PRP86984.1 - 0.18 11.9 2.5 0.47 10.6 0.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF406 PF04175.12 PRP86984.1 - 0.32 11.5 0.0 0.32 11.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF406) Steroid_dh PF02544.16 PRP86986.1 - 3.5e-37 127.7 7.3 1.6e-36 125.5 7.3 2.0 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 PRP86986.1 - 7.1e-06 25.7 0.1 7.1e-06 25.7 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) DUF3169 PF11368.8 PRP86986.1 - 0.034 13.7 1.7 0.043 13.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF4282 PF14110.6 PRP86986.1 - 5.9 7.7 8.1 8.5 7.2 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Carb_bind PF10645.9 PRP86987.1 - 0.003 17.7 4.3 0.003 17.7 4.3 4.7 3 1 1 4 4 4 2 Carbohydrate binding NUDE_C PF04880.13 PRP86987.1 - 9.2 6.7 6.9 15 6.1 6.9 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Usp PF00582.26 PRP86988.1 - 1.6e-15 57.8 0.4 4.9e-15 56.3 0.4 1.8 1 1 0 1 1 1 1 Universal stress protein family Acyl-CoA_dh_N PF02771.16 PRP86989.1 - 6.3e-29 100.9 0.1 1.2e-28 100.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 PRP86989.1 - 9.8e-27 94.0 0.1 1.7e-26 93.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PRP86989.1 - 1.2e-20 73.5 0.0 2.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PRP86989.1 - 5e-05 23.6 0.1 9.4e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNF2_N PF00176.23 PRP86990.1 - 7.1e-23 80.9 0.3 2e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 PRP86990.1 - 2e-12 47.1 0.0 2e-12 47.1 0.0 3.5 2 1 1 3 3 3 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 PRP86990.1 - 1.2e-07 32.0 0.2 5e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PRP86990.1 - 0.034 13.4 0.1 0.034 13.4 0.1 2.6 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 PRP86990.1 - 0.92 9.5 19.1 0.0088 16.0 10.0 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 PRP86990.1 - 4.8 7.1 9.9 21 5.1 9.9 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 PRP86991.1 - 0.0043 17.6 0.1 1.2 9.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP86991.1 - 0.069 13.7 0.0 0.66 10.6 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) SPRY PF00622.28 PRP86992.1 - 2.5e-24 85.7 0.3 6.1e-24 84.4 0.3 1.7 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 PRP86992.1 - 5.4e-12 45.4 0.5 1.6e-11 43.9 0.5 1.9 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 PRP86992.1 - 0.0031 18.0 0.4 0.0058 17.1 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 PRP86992.1 - 0.0034 17.2 0.4 0.0088 15.9 0.4 1.7 1 0 0 1 1 1 1 F-box domain MarB PF13999.6 PRP86992.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 MarB protein Pkinase PF00069.25 PRP86993.1 - 9.2e-58 195.7 0.0 1.1e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP86993.1 - 2.6e-35 122.0 0.0 3.4e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP86993.1 - 8.4e-05 22.0 0.0 0.00021 20.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 PRP86993.1 - 0.00023 21.2 0.0 0.0033 17.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP86993.1 - 0.00024 20.8 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PRP86993.1 - 0.0014 18.3 0.1 0.49 10.0 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PRP86993.1 - 0.0074 15.3 0.1 0.31 9.9 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 PRP86993.1 - 0.0097 15.5 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PRP86993.1 - 0.065 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PRP86993.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_gyraseB PF00204.25 PRP86993.1 - 0.085 12.3 0.4 0.14 11.6 0.4 1.3 1 0 0 1 1 1 0 DNA gyrase B CLU PF13236.6 PRP86994.1 - 6.7e-32 111.1 0.0 3.6e-18 66.2 0.0 3.2 2 1 0 2 2 2 2 Clustered mitochondria eIF3_p135 PF12807.7 PRP86994.1 - 4.2e-06 26.9 0.1 1.3e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 LRR_6 PF13516.6 PRP86994.1 - 9.2e-06 25.3 31.1 8.6 6.7 0.1 13.5 15 0 0 15 15 15 3 Leucine Rich repeat LRR_8 PF13855.6 PRP86994.1 - 0.00015 21.4 16.9 0.002 17.8 0.0 7.0 6 1 1 7 7 7 1 Leucine rich repeat LRR_4 PF12799.7 PRP86994.1 - 0.00028 21.2 44.4 0.31 11.5 0.2 10.7 6 3 6 13 13 13 5 Leucine Rich repeats (2 copies) Dcc1 PF09724.9 PRP86995.1 - 3.6e-67 227.0 0.0 4.1e-67 226.8 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HTH_32 PF13565.6 PRP86995.1 - 0.078 13.6 0.0 0.28 11.8 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain SAPS PF04499.15 PRP86996.1 - 2.7e-76 257.4 0.9 2.7e-42 145.2 1.0 3.5 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein Polyoma_agno PF01736.16 PRP86996.1 - 0.14 11.9 0.1 6.4 6.6 0.0 2.5 2 0 0 2 2 2 0 Polyomavirus agnoprotein YL1 PF05764.13 PRP86996.1 - 8.7 6.4 19.3 17 5.4 19.3 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Amidohydro_1 PF01979.20 PRP86997.1 - 4.2e-19 69.1 1.6 3.1e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 PRP86997.1 - 1.5e-18 67.6 2.4 3.1e-10 40.1 0.0 3.1 2 1 1 3 3 3 3 Amidohydrolase family ArfGap PF01412.18 PRP86998.1 - 1.8e-35 121.5 0.0 8.3e-35 119.4 0.0 2.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 PRP86998.1 - 4e-15 56.2 0.7 1.6e-14 54.3 0.2 2.4 2 0 0 2 2 2 1 PH domain HA PF03457.14 PRP86998.1 - 1.4e-08 34.9 0.0 4.5e-05 23.7 0.0 3.6 3 0 0 3 3 3 2 Helicase associated domain PH_3 PF14593.6 PRP86998.1 - 4.4e-06 26.7 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF5104 PF17117.5 PRP86998.1 - 0.024 15.1 0.9 0.87 10.1 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) PH_11 PF15413.6 PRP86998.1 - 0.79 10.2 4.0 0.42 11.1 0.4 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain GCP_C_terminal PF04130.13 PRP86999.1 - 4.6e-73 246.4 9.1 4.6e-73 246.4 9.1 1.8 2 1 1 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PRP86999.1 - 7.1e-73 245.9 0.4 1.4e-71 241.6 0.0 2.4 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Dzip-like_N PF13815.6 PRP87000.1 - 6.3e-31 106.8 4.0 6.3e-31 106.8 4.0 4.2 3 1 1 4 4 4 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal Pkinase_Tyr PF07714.17 PRP87000.1 - 5.7e-22 78.2 0.0 1.2e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87000.1 - 1.5e-15 57.3 0.1 9.9e-15 54.6 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain SH2 PF00017.24 PRP87000.1 - 1.3e-10 41.2 0.2 3.8e-10 39.7 0.2 1.9 1 0 0 1 1 1 1 SH2 domain F-box-like PF12937.7 PRP87000.1 - 4e-08 33.0 0.1 1.3e-07 31.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP87000.1 - 3.7e-06 26.7 0.1 9.8e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain PH PF00169.29 PRP87000.1 - 0.0007 20.1 4.3 0.054 14.0 0.7 3.6 3 1 0 3 3 2 1 PH domain DUF2935 PF11155.8 PRP87000.1 - 0.0024 18.2 0.0 4.3 7.7 0.0 3.5 2 2 0 2 2 2 1 Domain of unknown function (DUF2935) Kdo PF06293.14 PRP87000.1 - 0.0062 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_4 PF13894.6 PRP87000.1 - 0.013 16.3 1.6 0.013 16.3 1.6 2.5 2 0 0 2 2 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PRP87000.1 - 0.015 15.7 1.6 0.044 14.2 1.6 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 PRP87000.1 - 0.16 12.5 1.5 0.42 11.1 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain DUF2884 PF11101.8 PRP87000.1 - 0.61 9.6 11.0 1.7 8.1 11.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) YqzH PF14164.6 PRP87000.1 - 0.63 10.2 2.7 1.7 8.8 0.1 3.0 2 0 0 2 2 2 0 YqzH-like protein Zn-C2H2_12 PF18112.1 PRP87000.1 - 0.78 10.3 3.2 0.48 10.9 0.3 2.2 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4 PF00097.25 PRP87001.1 - 1.9e-08 34.0 7.0 1.9e-08 34.0 7.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP87001.1 - 5.8e-08 32.8 9.6 5.8e-08 32.8 9.6 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 PRP87001.1 - 7e-08 32.5 5.1 7e-08 32.5 5.1 2.9 3 0 0 3 3 3 1 B-box zinc finger zf-RING_UBOX PF13445.6 PRP87001.1 - 4.4e-07 29.8 5.1 4.4e-07 29.8 5.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP87001.1 - 7.3e-07 28.9 7.3 7.3e-07 28.9 7.3 2.6 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP87001.1 - 1.1e-06 28.3 19.8 6.8e-06 25.8 5.0 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP87001.1 - 9.5e-05 22.7 7.9 9.5e-05 22.7 7.9 2.6 2 0 0 2 2 2 1 Ring finger domain FHA_2 PF17913.1 PRP87001.1 - 0.00012 22.3 0.1 0.00046 20.4 0.0 2.0 2 0 0 2 2 1 1 FHA domain FHA PF00498.26 PRP87001.1 - 0.00014 22.1 0.1 0.00036 20.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_5 PF14634.6 PRP87001.1 - 0.0008 19.3 5.6 0.0008 19.3 5.6 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_5 PF17121.5 PRP87001.1 - 0.0021 17.9 2.4 0.0021 17.9 2.4 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) TBCC_N PF16752.5 PRP87001.1 - 0.041 14.3 1.1 0.13 12.7 1.1 1.9 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Yop-YscD_cpl PF16697.5 PRP87001.1 - 0.072 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain CEBP_ZZ PF16366.5 PRP87001.1 - 0.26 11.5 14.3 0.091 13.0 5.6 2.7 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 PRP87001.1 - 6.6 7.0 19.2 1.8 8.8 10.0 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain CCDC24 PF15669.5 PRP87002.1 - 1.3e-30 106.8 1.1 1.3e-30 106.8 1.1 1.5 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 24 family PPV_E1_N PF00524.18 PRP87002.1 - 0.1 13.0 0.6 0.56 10.6 0.0 2.3 2 1 1 3 3 3 0 E1 Protein, N terminal domain DUF5567 PF17722.1 PRP87003.1 - 0.00076 19.4 9.8 0.018 14.9 9.8 2.5 1 1 0 1 1 1 1 Family of unknown function (DUF5567) MFS_1 PF07690.16 PRP87005.1 - 1.3e-41 142.7 24.6 1.7e-41 142.3 24.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP87005.1 - 2.1e-31 109.3 18.4 2.6e-31 109.0 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 PRP87005.1 - 4.4e-09 35.4 12.8 3.4e-06 25.9 0.9 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 PRP87005.1 - 0.0022 16.5 1.7 0.0037 15.7 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EMP70 PF02990.16 PRP87005.1 - 5.7 5.5 10.6 3.7 6.1 3.8 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 DSPc PF00782.20 PRP87006.1 - 3.8e-33 114.1 1.1 3.8e-33 114.1 1.1 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP87006.1 - 9.9e-06 25.3 0.3 2.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP87006.1 - 0.019 15.0 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Abhydrolase_6 PF12697.7 PRP87007.1 - 2.8e-15 57.5 0.1 3.8e-15 57.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP87007.1 - 4.7e-10 39.1 0.2 1.4e-09 37.6 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP87007.1 - 3.2e-06 27.0 0.7 8.8e-06 25.5 0.4 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 PRP87007.1 - 0.026 14.6 0.2 0.055 13.6 0.2 1.6 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.25 PRP87007.1 - 0.036 13.9 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 PRP87007.1 - 0.071 12.8 0.3 0.66 9.6 0.1 2.3 3 0 0 3 3 3 0 PGAP1-like protein Abhydrolase_5 PF12695.7 PRP87007.1 - 0.14 11.9 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ras PF00071.22 PRP87008.1 - 2.7e-35 121.4 0.2 3.4e-35 121.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP87008.1 - 7.4e-22 77.8 0.0 1.4e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP87008.1 - 2.2e-11 43.5 0.0 3.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PRP87008.1 - 0.0008 18.9 0.0 0.0026 17.2 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP-synt_ab PF00006.25 PRP87008.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain TniB PF05621.11 PRP87008.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 PRP87008.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 PRP87008.1 - 0.019 15.3 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 PRP87008.1 - 0.025 14.3 0.0 0.11 12.2 0.0 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 PRP87008.1 - 0.053 14.0 0.0 0.07 13.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 PRP87008.1 - 0.06 12.5 1.3 3.1 6.9 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit MCM PF00493.23 PRP87008.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 PRP87008.1 - 0.12 11.9 0.0 1.2 8.7 0.0 2.3 2 1 1 3 3 3 0 AAA domain DLIC PF05783.11 PRP87008.1 - 0.14 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Mss4 PF04421.13 PRP87009.1 - 4.6e-22 78.0 0.0 7.3e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Mss4 protein zf-C2H2_jaz PF12171.8 PRP87010.1 - 1.8e-06 28.1 4.7 5e-06 26.6 4.7 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP87010.1 - 2.5e-06 27.7 3.0 6.6e-06 26.3 3.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PRP87010.1 - 0.0032 17.8 1.9 0.017 15.4 0.3 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 PRP87010.1 - 0.0044 17.7 0.3 0.016 16.0 0.3 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger AKAP95 PF04988.12 PRP87010.1 - 0.011 16.0 0.7 0.022 15.0 0.7 1.7 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 PRP87010.1 - 0.014 15.8 0.9 0.039 14.4 0.9 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PRP87010.1 - 0.042 13.8 1.8 0.094 12.7 1.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-U1 PF06220.12 PRP87010.1 - 0.067 13.0 0.9 0.17 11.7 0.9 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-H2C2_2 PF13465.6 PRP87010.1 - 0.08 13.4 0.2 0.29 11.6 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger double domain MAS20 PF02064.15 PRP87010.1 - 0.41 10.7 6.0 0.81 9.8 2.6 2.6 3 0 0 3 3 3 0 MAS20 protein import receptor RGS_DHEX PF18148.1 PRP87010.1 - 1.3 9.2 4.9 19 5.4 0.2 3.1 3 0 0 3 3 3 0 Regulator of G-protein signalling DHEX domain GDPD PF03009.17 PRP87011.1 - 5.7e-46 157.3 0.0 6.9e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4394 PF14339.6 PRP87012.1 - 2.1e-22 79.6 0.3 5.3e-22 78.3 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4394) SMC_N PF02463.19 PRP87013.1 - 3.5e-20 72.4 0.0 8.5e-20 71.1 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PRP87013.1 - 3.8e-12 47.1 63.5 1e-08 36.0 27.8 5.0 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 PRP87013.1 - 0.0012 18.7 12.0 0.0035 17.2 0.7 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 PRP87013.1 - 0.0056 17.1 1.6 4.6 7.7 0.2 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 PRP87013.1 - 0.0093 15.7 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 PRP87013.1 - 0.04 13.5 0.1 0.04 13.5 0.1 2.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 PRP87013.1 - 0.12 12.8 0.9 5.3 7.4 0.2 3.2 1 1 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 PRP87013.1 - 0.13 11.9 0.0 0.13 11.9 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 PRP87013.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Gly_acyl_tr_C PF08444.10 PRP87013.1 - 0.79 10.0 2.4 16 5.8 0.0 3.5 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region HATPase_c PF02518.26 PRP87014.1 - 2.3e-29 102.2 1.1 7.7e-29 100.5 0.8 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP87014.1 - 7.9e-19 67.9 0.8 2.4e-18 66.4 0.8 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 PRP87014.1 - 9.5e-14 51.2 0.1 3.5e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP87014.1 - 1.2e-05 25.2 0.2 3e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PRP87015.1 - 2.4e-24 86.0 0.4 1.1e-23 83.8 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP87015.1 - 5.3e-22 78.1 0.9 1.8e-21 76.4 0.9 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 PRP87015.1 - 2.4e-12 46.7 2.8 1.5e-11 44.2 0.0 3.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_5 PF14501.6 PRP87015.1 - 0.0028 17.5 0.0 0.044 13.7 0.0 2.8 2 0 0 2 2 2 1 GHKL domain PAS_9 PF13426.7 PRP87015.1 - 0.0048 17.1 0.1 0.76 10.1 0.0 4.0 4 0 0 4 4 4 1 PAS domain Adeno_E3_15_3 PF03307.14 PRP87015.1 - 0.082 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region VPS9 PF02204.18 PRP87016.1 - 5.5e-19 68.3 0.1 1.4e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Nbl1_Borealin_N PF10444.9 PRP87017.1 - 9.2e-15 54.0 2.6 9.2e-15 54.0 2.6 2.3 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal YgbB PF02542.16 PRP87017.1 - 0.06 13.6 0.2 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 YgbB family KxDL PF10241.9 PRP87017.1 - 0.1 12.9 11.8 0.9 9.9 1.0 3.3 2 2 1 3 3 3 0 Uncharacterized conserved protein T3SS_basalb_I PF17001.5 PRP87017.1 - 1.8 9.2 13.8 0.14 12.7 2.9 3.0 2 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Filamin PF00630.19 PRP87018.1 - 1.3e-24 87.0 1.1 1.5e-08 35.3 0.2 5.4 5 1 0 5 5 5 4 Filamin/ABP280 repeat Invasin_D3 PF09134.10 PRP87018.1 - 1.8e-13 50.6 13.7 0.0012 19.1 0.1 5.0 4 1 0 4 4 4 4 Invasin, domain 3 Lectin_legB PF00139.19 PRP87018.1 - 1.9e-11 44.0 2.2 1.9e-11 44.0 2.2 2.4 2 0 0 2 2 2 1 Legume lectin domain YtkA PF13115.6 PRP87018.1 - 0.021 15.4 1.1 0.3 11.7 0.1 3.3 3 0 0 3 3 3 0 YtkA-like Podoplanin PF05808.11 PRP87018.1 - 0.023 14.8 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 Podoplanin ThuA PF06283.11 PRP87018.1 - 0.034 14.3 0.2 0.087 13.0 0.1 1.7 2 0 0 2 2 2 0 Trehalose utilisation FIT1_2 PF17357.2 PRP87018.1 - 0.047 13.8 0.2 0.31 11.1 0.2 2.5 1 0 0 1 1 1 0 Facilitor Of iron transport 1 and 2 GPI-anchored PF10342.9 PRP87018.1 - 0.96 10.3 9.8 0.66 10.8 0.8 4.9 5 1 1 6 6 6 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glutaredoxin PF00462.24 PRP87019.1 - 5.5e-30 103.4 0.0 9.4e-18 64.2 0.0 2.6 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 PRP87019.1 - 1e-13 51.1 0.1 2.9e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PRP87019.1 - 0.0042 16.5 0.2 0.0054 16.1 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 PRP87019.1 - 0.0071 16.3 0.2 0.029 14.3 0.2 1.9 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE SH3BGR PF04908.15 PRP87019.1 - 0.016 15.4 0.1 3.2 8.0 0.0 3.1 2 1 0 2 2 2 0 SH3-binding, glutamic acid-rich protein DUF1411 PF07199.11 PRP87019.1 - 0.029 14.0 0.5 0.59 9.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1411) Thioredoxin_2 PF13098.6 PRP87019.1 - 0.034 14.6 0.0 0.29 11.6 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like domain DUF1590 PF07629.11 PRP87019.1 - 0.17 11.7 0.0 25 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) Ribosomal_60s PF00428.19 PRP87019.1 - 1.6 9.4 7.0 0.24 12.0 1.7 2.4 2 1 1 3 3 3 0 60s Acidic ribosomal protein SWIB PF02201.18 PRP87020.1 - 6e-19 67.7 0.1 1.5e-18 66.4 0.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Oxidored_molyb PF00174.19 PRP87021.1 - 2.1e-44 151.1 0.0 5.7e-44 149.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PRP87021.1 - 9.5e-36 122.8 1.1 9.5e-36 122.8 1.1 2.3 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 PRP87021.1 - 3.6e-27 95.2 0.0 3.6e-27 95.2 0.0 2.9 3 1 0 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PRP87021.1 - 5.5e-23 81.2 0.0 1e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 PRP87021.1 - 1.2e-14 54.2 0.1 2.7e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 PRP87021.1 - 0.014 15.5 0.0 0.014 15.5 0.0 3.8 2 2 1 3 3 3 0 Ferric reductase NAD binding domain UQ_con PF00179.26 PRP87022.1 - 2.6e-44 150.3 0.1 3e-44 150.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PUF PF00806.19 PRP87023.1 - 3.8e-66 215.2 15.9 7.3e-09 34.8 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF5432 PF17497.2 PRP87023.1 - 0.14 12.3 0.0 0.94 9.6 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5432) DUF572 PF04502.13 PRP87024.1 - 1.4 8.5 2.9 1.6 8.2 2.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pkinase PF00069.25 PRP87025.1 - 6.7e-46 156.8 0.3 1e-44 152.9 0.3 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87025.1 - 2e-15 56.8 0.3 6.3e-15 55.2 0.3 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA-synt_His PF13393.6 PRP87027.1 - 1e-34 120.2 0.0 1.9e-34 119.4 0.0 1.4 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 PRP87027.1 - 1.3e-21 77.4 0.0 2.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PRP87027.1 - 1.4e-08 34.8 1.1 1.2e-07 31.8 0.2 2.5 2 1 1 3 3 3 1 Anticodon binding domain tRNA-synt_2d PF01409.20 PRP87027.1 - 0.00057 19.4 0.5 0.0019 17.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) S_2TMBeta PF18153.1 PRP87027.1 - 0.0088 15.8 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 1 SMODS-associating 2TM, beta-strand rich effector domain RYDR_ITPR PF01365.21 PRP87028.1 - 4.8e-21 75.1 12.0 8.5e-12 44.9 0.7 3.7 3 0 0 3 3 3 2 RIH domain RIH_assoc PF08454.11 PRP87028.1 - 8.7e-13 48.0 16.2 4.6e-12 45.7 1.4 6.2 5 0 0 5 5 5 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 PRP87028.1 - 1.1e-10 41.0 0.0 2.8e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 PRP87028.1 - 2.7e-08 33.3 12.8 2.7e-08 33.3 12.8 2.1 2 0 0 2 2 2 1 Ion transport protein MIR PF02815.19 PRP87028.1 - 5.5e-07 29.6 0.3 0.00061 19.7 0.1 2.5 2 0 0 2 2 2 2 MIR domain Coatomer_WDAD PF04053.14 PRP87029.1 - 1.2e-167 558.5 0.2 8e-167 555.8 0.0 2.1 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 PRP87029.1 - 5.7e-33 112.4 3.5 1.3e-06 29.0 0.1 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 PRP87029.1 - 0.0028 17.7 0.1 3.8 7.6 0.0 3.3 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Rib_recp_KP_reg PF05104.12 PRP87029.1 - 0.014 16.4 9.1 0.03 15.4 9.1 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region RCC1 PF00415.18 PRP87030.1 - 3.5e-81 267.6 20.5 2.8e-15 56.6 0.3 7.6 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP87030.1 - 5.3e-31 105.8 41.1 7.2e-07 28.9 0.4 8.5 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Chlam_PMP PF02415.17 PRP87030.1 - 0.027 15.0 2.0 0.088 13.3 2.0 2.0 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat I_LWEQ PF01608.17 PRP87031.1 - 2.1e-60 203.4 177.8 8.6e-45 152.7 7.7 17.8 6 5 10 18 18 18 15 I/LWEQ domain FERM_f0 PF16511.5 PRP87031.1 - 4.2e-29 100.7 0.2 5.3e-22 77.9 0.0 3.0 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 PRP87031.1 - 5e-22 78.5 1.0 1.5e-19 70.6 0.0 4.0 3 0 0 3 3 3 1 FERM central domain VHP PF02209.19 PRP87031.1 - 2.4e-14 53.1 0.5 5.7e-14 51.9 0.5 1.7 1 0 0 1 1 1 1 Villin headpiece domain FERM_N PF09379.10 PRP87031.1 - 2e-09 37.2 0.1 5.5e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 FERM N-terminal domain Talin_middle PF09141.10 PRP87031.1 - 1.8e-05 24.8 6.9 1.8e-05 24.8 6.9 18.1 7 3 10 17 17 16 3 Talin, middle domain Coat_F PF07875.12 PRP87031.1 - 0.00064 19.9 0.6 3.8 7.8 0.0 4.4 3 0 0 3 3 3 2 Coat F domain IRS PF02174.17 PRP87031.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 PTB domain (IRS-1 type) RA PF00788.23 PRP87031.1 - 0.052 14.2 0.0 0.18 12.5 0.0 1.9 2 0 0 2 2 1 0 Ras association (RalGDS/AF-6) domain VBS PF08913.10 PRP87031.1 - 0.052 14.0 102.5 0.018 15.5 1.4 13.4 11 4 3 14 14 14 0 Vinculin Binding Site FRB_dom PF08771.11 PRP87031.1 - 0.27 11.7 2.2 1.9 8.9 0.2 3.6 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain DUF5616 PF18481.1 PRP87031.1 - 0.27 11.6 5.6 3.9 7.8 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5616) LOH1CR12 PF10158.9 PRP87031.1 - 2.4 8.2 6.1 3.6 7.6 0.2 4.7 3 2 1 4 4 4 0 Tumour suppressor protein Sec2p PF06428.11 PRP87032.1 - 4e-12 45.9 9.3 4e-12 45.9 9.3 2.7 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p AIG1 PF04548.16 PRP87032.1 - 1.5 8.1 9.3 0.47 9.7 1.6 2.2 1 1 0 2 2 2 0 AIG1 family TPR_MLP1_2 PF07926.12 PRP87032.1 - 2.3 8.3 33.2 61 3.7 7.4 3.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Taxilin PF09728.9 PRP87032.1 - 4.9 6.2 30.4 0.19 10.9 18.3 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein KxDL PF10241.9 PRP87032.1 - 8.7 6.7 17.8 0.8 10.0 2.7 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein Njmu-R1 PF15053.6 PRP87033.1 - 9.2e-21 74.3 2.0 1.2e-18 67.3 0.8 2.2 2 0 0 2 2 2 2 Mjmu-R1-like protein family SMC_ScpB PF04079.16 PRP87033.1 - 0.11 12.2 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Cpn60_TCP1 PF00118.24 PRP87034.1 - 1e-147 492.7 12.1 1.2e-147 492.6 12.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family 2-oxoacid_dh PF00198.23 PRP87035.1 - 1e-30 106.9 0.1 1.3e-30 106.6 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) HSP70 PF00012.20 PRP87036.1 - 4.5e-254 844.2 16.2 5.3e-254 843.9 16.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP87036.1 - 3.3e-17 62.3 0.3 4.4e-16 58.6 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein ATG27 PF09451.10 PRP87036.1 - 3.7e-07 30.3 0.0 8.4e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 PRP87036.1 - 7.4e-06 25.2 0.1 7.4e-06 25.2 0.1 2.5 3 0 0 3 3 3 1 Mannose-6-phosphate receptor Mannosyl_trans2 PF04188.13 PRP87036.1 - 0.033 13.5 0.3 0.049 12.9 0.3 1.2 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) FGGY_C PF02782.16 PRP87036.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 PRP87036.1 - 0.054 12.7 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 PRP87036.1 - 0.24 11.8 4.5 23 5.5 0.2 3.6 3 1 0 3 3 3 0 Cell division protein FtsA Pex19 PF04614.12 PRP87036.1 - 0.27 11.0 11.4 0.026 14.3 4.0 2.1 2 0 0 2 2 2 0 Pex19 protein family Smg8_Smg9 PF10220.9 PRP87037.1 - 1.5e-12 46.8 0.1 1.9e-12 46.4 0.1 1.1 1 0 0 1 1 1 1 Smg8_Smg9 TerD PF02342.18 PRP87038.1 - 1.3e-17 63.9 0.0 3.7e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 TerD domain UQ_con PF00179.26 PRP87038.1 - 1.7e-09 37.5 0.1 5.1e-09 35.9 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box PF00646.33 PRP87038.1 - 3.6e-05 23.5 0.1 9.1e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP87038.1 - 0.0017 18.2 0.4 0.004 17.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 PRP87039.1 - 2.9e-36 122.9 39.8 6.5e-08 32.8 2.3 7.5 4 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP87039.1 - 1e-27 96.7 17.3 2.3e-14 53.3 1.3 3.9 1 1 4 5 5 5 5 Leucine-rich repeat LRR_8 PF13855.6 PRP87039.1 - 4e-24 84.2 32.6 1.3e-07 31.2 1.4 6.8 4 1 2 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 PRP87039.1 - 6.6e-05 22.6 16.8 1.6 9.0 0.0 8.0 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 PRP87039.1 - 9e-05 22.5 33.5 4 8.4 0.1 10.7 11 3 0 11 11 11 4 Leucine Rich Repeat Peptidase_M16 PF00675.20 PRP87040.1 - 6.4e-54 182.0 0.6 5.6e-53 178.9 0.2 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PRP87040.1 - 1.1e-35 123.4 0.1 6.7e-34 117.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain KfrA_N PF11740.8 PRP87040.1 - 0.0038 17.9 0.0 0.015 16.0 0.0 2.0 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term M16C_assoc PF08367.11 PRP87040.1 - 0.03 13.4 0.6 0.097 11.8 0.2 2.0 2 1 0 2 2 2 0 Peptidase M16C associated FMN_dh PF01070.18 PRP87041.1 - 1.1e-124 416.0 0.7 1.3e-124 415.7 0.7 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 PRP87041.1 - 2.3e-16 59.7 0.0 5.4e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 PRP87041.1 - 5.6e-09 35.6 0.2 1.1e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 PRP87041.1 - 3.1e-06 26.4 1.7 5.7e-06 25.6 1.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 PRP87041.1 - 0.00055 19.4 1.0 0.00095 18.6 0.8 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 PRP87041.1 - 0.0044 16.5 0.3 0.011 15.3 0.2 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 PRP87041.1 - 0.011 15.1 0.1 1.3 8.3 0.1 2.4 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Salt_tol_Pase PF09506.10 PRP87041.1 - 0.031 13.0 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) DHO_dh PF01180.21 PRP87041.1 - 0.1 11.8 0.1 11 5.1 0.1 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Mic1 PF07035.12 PRP87042.1 - 1.6e-49 167.6 2.3 3.2e-49 166.6 2.3 1.5 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Arf PF00025.21 PRP87043.1 - 6.4e-55 185.3 0.1 8e-55 185.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PRP87043.1 - 1e-12 47.9 0.1 1.3e-12 47.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP87043.1 - 2.3e-11 43.9 0.0 4.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PRP87043.1 - 1.3e-08 34.5 0.1 1.6e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PRP87043.1 - 4.1e-08 32.9 0.0 5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PRP87043.1 - 4.7e-06 26.0 1.6 0.012 14.8 0.5 2.7 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PRP87043.1 - 0.0016 18.5 0.0 0.003 17.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 PRP87043.1 - 0.0027 16.7 0.1 0.0042 16.1 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 PRP87043.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain LIM PF00412.22 PRP87045.1 - 4.2e-10 39.7 5.4 1.1e-09 38.4 5.4 1.8 1 0 0 1 1 1 1 LIM domain zinc_ribbon_12 PF11331.8 PRP87045.1 - 0.0013 18.5 1.6 0.0013 18.5 1.6 2.1 2 0 0 2 2 2 1 Probable zinc-ribbon domain TRAF_BIRC3_bd PF16673.5 PRP87045.1 - 0.17 11.7 9.0 0.32 10.8 2.2 3.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain T2SSM PF04612.12 PRP87045.1 - 0.18 11.9 5.6 0.63 10.1 3.2 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M DivIC PF04977.15 PRP87045.1 - 2.4 8.0 5.2 8.6 6.2 5.2 1.9 1 0 0 1 1 1 0 Septum formation initiator Herpes_US12 PF05363.12 PRP87045.1 - 2.9 8.7 15.5 0.82 10.4 0.4 5.3 2 1 2 5 5 5 0 Herpesvirus US12 family Cyclase PF04199.13 PRP87046.1 - 1e-10 42.0 0.0 1.2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Kelch_5 PF13854.6 PRP87047.1 - 1.5e-39 133.4 2.4 1.3e-07 31.5 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 PRP87047.1 - 1.7e-35 120.7 11.3 1.8e-09 37.5 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 PRP87047.1 - 3.9e-30 103.2 0.7 1.2e-08 34.4 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PRP87047.1 - 6.2e-27 93.0 5.1 5e-08 32.9 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 PRP87047.1 - 2.1e-26 91.6 16.6 1.7e-08 34.5 0.5 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP87047.1 - 6.2e-22 76.7 4.4 0.00028 20.7 0.1 6.5 6 0 0 6 6 6 5 Kelch motif SAM_1 PF00536.30 PRP87047.1 - 2e-19 69.8 0.0 3.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP87047.1 - 3.6e-15 55.8 0.0 7.8e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMMR_N PF15905.5 PRP87047.1 - 0.096 12.1 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF5612 PF18462.1 PRP87047.1 - 0.24 11.2 0.6 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5612) Amidohydro_1 PF01979.20 PRP87048.1 - 3.6e-24 85.7 0.5 1e-23 84.2 0.5 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PRP87048.1 - 5.2e-11 42.7 1.8 2.8e-08 33.7 0.0 2.6 2 1 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 PRP87048.1 - 3.8e-06 26.9 0.2 7.7e-06 25.9 0.1 1.6 2 0 0 2 2 2 1 Amidohydrolase MFS_1 PF07690.16 PRP87050.1 - 1.7e-12 47.0 35.3 1.7e-12 47.0 35.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 PRP87050.1 - 3.4e-09 36.6 7.1 3.4e-09 36.6 7.1 2.8 4 0 0 4 4 4 1 Ion channel regulatory protein UNC-93 DUF1751 PF08551.10 PRP87051.1 - 1.2e-21 77.1 1.4 1.2e-21 77.1 1.4 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 PRP87051.1 - 1.6e-05 24.9 11.2 3.3e-05 23.9 11.2 1.4 1 0 0 1 1 1 1 Rhomboid family Methyltransf_16 PF10294.9 PRP87052.1 - 7.1e-14 51.9 0.2 1.7e-13 50.7 0.2 1.6 1 1 0 1 1 1 1 Lysine methyltransferase MRP-S28 PF10213.9 PRP87053.1 - 5e-09 36.6 0.1 1.3e-08 35.3 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Fascin PF06268.13 PRP87054.1 - 2.6e-08 34.1 0.2 7e-06 26.2 0.1 2.1 1 1 1 2 2 2 2 Fascin domain RET_CLD1 PF17756.1 PRP87054.1 - 0.0071 16.6 3.9 0.062 13.6 0.0 2.6 2 1 1 3 3 3 1 RET Cadherin like domain 1 FRG1 PF06229.12 PRP87054.1 - 0.048 13.4 0.0 1.4 8.6 0.0 2.3 1 1 0 2 2 2 0 FRG1-like domain DUF4106 PF13388.6 PRP87054.1 - 0.13 11.4 8.8 0.17 11.1 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) PS_Dcarbxylase PF02666.15 PRP87056.1 - 5.5e-49 166.4 0.0 9.2e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Kelch_1 PF01344.25 PRP87056.1 - 1.6e-33 114.0 4.1 5.3e-09 35.5 0.1 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 PRP87056.1 - 1.9e-29 100.9 10.0 8.7e-10 38.5 0.0 7.3 6 1 1 7 7 7 5 Kelch motif Kelch_4 PF13418.6 PRP87056.1 - 1.4e-25 89.0 12.0 4.1e-06 26.7 0.1 6.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 PRP87056.1 - 1.4e-23 82.7 12.8 8.1e-07 29.2 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP87056.1 - 1.9e-21 75.6 7.7 5.1e-05 23.2 0.0 6.6 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 PRP87056.1 - 2.2e-21 74.9 8.7 2.6e-06 27.2 0.1 5.6 5 0 0 5 5 5 3 Kelch motif F-box-like PF12937.7 PRP87056.1 - 2.7e-09 36.8 3.4 5e-09 35.9 1.5 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP87056.1 - 7.8e-05 22.5 0.7 0.00017 21.4 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP87056.1 - 0.002 18.0 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 F-box Myb_DNA-binding PF00249.31 PRP87058.1 - 4e-05 23.7 0.0 8.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain PDEase_I PF00233.19 PRP87059.1 - 1.8e-77 260.3 1.7 2.7e-77 259.7 1.7 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase MFS_1 PF07690.16 PRP87060.1 - 5.9e-38 130.7 43.5 1e-31 110.2 28.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 PRP87060.1 - 8.3e-09 34.8 9.2 8.3e-09 34.8 9.2 1.9 2 0 0 2 2 2 1 MFS_1 like family DUF3948 PF13134.6 PRP87060.1 - 0.0083 15.8 0.1 0.024 14.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3948) Claudin_2 PF13903.6 PRP87060.1 - 0.033 13.9 9.8 0.067 12.9 0.2 3.7 2 1 2 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction DUF3989 PF13150.6 PRP87060.1 - 5.9 6.7 6.1 0.8 9.5 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) Sacchrp_dh_C PF16653.5 PRP87061.1 - 2.8e-74 250.6 0.0 4.8e-74 249.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 PRP87061.1 - 2.5e-17 63.4 0.0 5.7e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 PRP87061.1 - 1.5e-07 31.5 0.0 3.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase LisH_TPL PF17814.1 PRP87061.1 - 1.3e-05 24.8 0.4 1.3e-05 24.8 0.4 1.9 2 0 0 2 2 2 1 LisH-like dimerisation domain LisH PF08513.11 PRP87061.1 - 0.011 15.7 0.1 0.031 14.2 0.1 1.8 1 0 0 1 1 1 0 LisH NAD_binding_2 PF03446.15 PRP87061.1 - 0.058 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gastrin PF00918.17 PRP87061.1 - 0.098 13.6 1.0 0.47 11.4 0.0 2.5 3 0 0 3 3 3 0 Gastrin/cholecystokinin family NIF PF03031.18 PRP87062.1 - 7e-51 172.1 0.2 1.1e-50 171.4 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TFIIE-A_C PF11521.8 PRP87062.1 - 6.8 7.1 7.7 0.75 10.1 0.1 2.8 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha COG4 PF08318.12 PRP87064.1 - 5.3e-62 209.8 6.9 1.6e-61 208.3 6.9 1.8 1 1 0 1 1 1 1 COG4 transport protein Sec10 PF07393.11 PRP87064.1 - 1.3e-05 23.9 11.1 1.3e-05 23.9 11.1 2.7 2 2 1 3 3 3 1 Exocyst complex component Sec10 DIL PF01843.19 PRP87064.1 - 0.00016 21.9 1.0 0.00071 19.8 0.4 2.4 2 0 0 2 2 2 1 DIL domain DUF3583 PF12126.8 PRP87064.1 - 0.00029 20.4 0.7 0.001 18.6 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3583) DUF948 PF06103.11 PRP87064.1 - 0.0015 18.8 4.2 0.041 14.1 0.1 4.1 4 1 0 4 4 4 1 Bacterial protein of unknown function (DUF948) CRISPR_Cas2 PF09827.9 PRP87064.1 - 0.064 13.5 0.4 0.34 11.1 0.1 2.4 2 0 0 2 2 2 0 CRISPR associated protein Cas2 TPR_2 PF07719.17 PRP87064.1 - 0.19 11.9 0.7 0.9 9.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TBCA PF02970.16 PRP87064.1 - 0.58 10.5 8.6 8.3 6.8 1.5 3.2 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF3427 PF11907.8 PRP87064.1 - 0.81 8.9 8.5 0.057 12.7 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3427) Ribosomal_S5 PF00333.20 PRP87065.1 - 6.5e-17 61.3 4.3 1.2e-16 60.4 4.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 PRP87065.1 - 5.4e-15 54.6 0.0 9.3e-15 53.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain MinC_C PF03775.16 PRP87065.1 - 0.036 14.1 1.1 0.074 13.1 0.2 2.0 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain WD40 PF00400.32 PRP87067.1 - 5.2e-45 150.5 18.6 1.4e-07 32.1 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP87067.1 - 2.3e-12 47.0 3.5 0.041 14.2 0.0 6.3 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP87067.1 - 2.3e-06 26.8 3.9 0.00045 19.3 0.1 3.8 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP87067.1 - 4.7e-05 23.3 1.5 0.031 14.2 0.0 2.7 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 PRP87067.1 - 0.00083 18.8 1.9 0.099 11.9 0.0 3.3 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 PRP87067.1 - 0.0019 16.9 2.6 0.061 12.0 0.3 3.3 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PRP87067.1 - 0.016 14.0 0.2 0.28 9.9 0.0 2.8 2 1 0 3 3 3 0 Nup133 N terminal like XRCC4 PF06632.12 PRP87068.1 - 8.2e-16 57.8 6.4 1.1e-14 54.0 6.4 2.3 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 HR1 PF02185.16 PRP87068.1 - 0.13 12.4 1.8 0.25 11.5 1.8 1.5 1 0 0 1 1 1 0 Hr1 repeat adh_short PF00106.25 PRP87070.1 - 2.6e-38 131.4 0.0 4.4e-38 130.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP87070.1 - 1.8e-29 103.0 0.0 2.7e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 PRP87070.1 - 3.5e-10 39.8 0.1 7.2e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PAXX PF15384.6 PRP87070.1 - 4.6e-10 39.5 0.2 1.8e-09 37.6 0.2 1.8 1 1 0 1 1 1 1 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 KR PF08659.10 PRP87070.1 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Colicin PF01024.19 PRP87070.1 - 0.0039 17.1 0.0 0.44 10.4 0.0 2.9 3 0 0 3 3 3 1 Colicin pore forming domain Epimerase PF01370.21 PRP87070.1 - 0.0047 16.4 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP87070.1 - 0.073 12.4 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PRP87070.1 - 0.15 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ctr PF04145.15 PRP87071.1 - 0.013 16.2 0.4 0.021 15.4 0.2 1.4 1 1 0 1 1 1 0 Ctr copper transporter family GTP_EFTU PF00009.27 PRP87072.1 - 4.1e-24 85.2 0.0 9.1e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PRP87072.1 - 2.7e-07 30.9 0.3 3.6e-06 27.3 0.1 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Dynamin_N PF00350.23 PRP87072.1 - 0.00055 20.0 0.1 0.00055 20.0 0.1 2.3 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PRP87072.1 - 0.00096 19.2 0.0 0.0048 17.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 PRP87072.1 - 0.016 14.2 0.1 0.035 13.2 0.1 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Arf PF00025.21 PRP87072.1 - 0.062 12.7 0.1 5.2 6.5 0.0 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family Casein_kappa PF00997.18 PRP87072.1 - 0.11 12.6 5.9 0.24 11.5 5.9 1.5 1 0 0 1 1 1 0 Kappa casein ATP_bind_1 PF03029.17 PRP87072.1 - 0.15 11.8 1.3 1.3 8.7 1.3 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein tRNA-synt_2b PF00587.25 PRP87073.1 - 2.2e-40 138.6 0.0 3.2e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PRP87073.1 - 4.2e-18 65.6 4.2 4.2e-18 65.6 4.2 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Cas_Csx9 PF09658.10 PRP87073.1 - 0.091 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) AAA_6 PF12774.7 PRP87074.1 - 1.3e-145 484.5 0.0 1.1e-144 481.4 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PRP87074.1 - 2.9e-111 372.4 14.5 2.9e-111 372.4 14.5 3.6 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PRP87074.1 - 5.4e-78 262.3 0.0 1.7e-77 260.6 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PRP87074.1 - 8.4e-66 221.2 6.9 2.1e-64 216.7 1.2 3.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 PRP87074.1 - 1.5e-65 221.2 0.0 1.5e-65 221.2 0.0 3.0 4 0 0 4 4 2 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 PRP87074.1 - 6e-51 172.5 0.0 1.7e-50 171.0 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 PRP87074.1 - 3e-48 164.6 9.4 5.7e-48 163.7 9.4 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PRP87074.1 - 1.8e-41 141.0 0.1 1.3e-40 138.2 0.0 2.7 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 PRP87074.1 - 3.6e-32 111.3 0.3 6.1e-25 87.8 0.0 4.5 4 1 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 PRP87074.1 - 1.7e-20 73.4 0.2 2.9e-07 30.6 0.0 6.7 6 2 0 6 6 6 3 AAA domain (dynein-related subfamily) AP-5_subunit_s1 PF15001.6 PRP87074.1 - 1.3e-19 70.9 0.6 1.7e-18 67.3 0.6 2.6 1 1 0 1 1 1 1 AP-5 complex subunit sigma-1 AAA PF00004.29 PRP87074.1 - 2.6e-15 57.0 0.1 4.6e-05 23.8 0.0 5.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 PRP87074.1 - 3.3e-14 53.1 0.9 2.7e-13 50.1 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 PRP87074.1 - 3.6e-12 47.0 10.8 0.0059 17.0 0.0 7.8 7 1 0 7 7 6 2 AAA ATPase domain AAA_18 PF13238.6 PRP87074.1 - 1e-08 35.7 0.0 0.037 14.6 0.0 4.4 3 0 0 3 3 3 2 AAA domain AAA_lid_1 PF17857.1 PRP87074.1 - 1.4e-07 31.6 0.0 5.7e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PRP87074.1 - 1.6e-07 31.6 11.2 0.032 14.5 0.0 6.5 7 0 0 7 7 5 2 AAA domain RNA_helicase PF00910.22 PRP87074.1 - 3.5e-07 30.6 0.0 0.59 10.5 0.0 4.0 3 0 0 3 3 3 2 RNA helicase NACHT PF05729.12 PRP87074.1 - 5.9e-07 29.5 0.0 0.019 14.9 0.0 3.7 3 0 0 3 3 3 2 NACHT domain Rad17 PF03215.15 PRP87074.1 - 7e-07 29.3 2.2 0.053 13.4 0.0 4.8 4 0 0 4 4 4 1 Rad17 P-loop domain AAA_30 PF13604.6 PRP87074.1 - 1.4e-06 28.2 3.0 0.47 10.1 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 PRP87074.1 - 2e-06 28.0 1.0 0.37 10.9 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.6 PRP87074.1 - 2.6e-06 27.5 0.0 0.0094 16.0 0.0 4.3 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 PRP87074.1 - 3.4e-06 26.4 0.2 0.038 13.2 0.0 4.0 3 0 0 3 3 3 2 NB-ARC domain ABC_tran PF00005.27 PRP87074.1 - 2.6e-05 24.7 4.0 0.14 12.7 0.0 4.6 4 0 0 4 4 3 2 ABC transporter ATPase_2 PF01637.18 PRP87074.1 - 7.6e-05 22.7 7.1 0.0017 18.3 0.0 4.8 6 0 0 6 6 4 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 PRP87074.1 - 0.00017 20.8 0.0 0.3 10.1 0.0 3.0 2 0 0 2 2 2 2 Type II/IV secretion system protein Mg_chelatase PF01078.21 PRP87074.1 - 0.00023 20.6 1.1 0.12 11.8 0.0 3.4 4 0 0 4 4 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PRP87074.1 - 0.00023 20.9 0.4 14 5.4 0.1 5.1 5 0 0 5 5 5 0 AAA domain TsaE PF02367.17 PRP87074.1 - 0.0012 18.9 1.6 0.57 10.2 0.0 4.0 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 PRP87074.1 - 0.0015 18.2 0.1 3.1 7.4 0.0 3.8 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin PF02224.18 PRP87074.1 - 0.0022 17.8 0.6 1.1 9.0 0.0 3.3 3 0 0 3 3 2 1 Cytidylate kinase AAA_28 PF13521.6 PRP87074.1 - 0.0031 17.8 4.2 3.2 8.0 0.0 4.3 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.26 PRP87074.1 - 0.0034 17.1 0.4 6.2 6.5 0.0 3.7 4 0 0 4 4 4 0 Sigma-54 interaction domain RuvB_N PF05496.12 PRP87074.1 - 0.0073 16.1 0.1 4.5 7.0 0.0 4.0 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 PRP87074.1 - 0.013 15.9 2.8 13 6.1 0.0 3.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 PRP87074.1 - 0.024 14.2 0.1 37 3.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 PRP87074.1 - 0.041 13.9 1.1 5.4 7.0 0.0 4.5 4 1 0 5 5 3 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 PRP87074.1 - 0.062 13.1 0.0 2.1 8.1 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 PRP87074.1 - 0.064 13.1 6.2 13 5.6 0.0 5.0 6 0 0 6 6 5 0 RsgA GTPase TGS PF02824.21 PRP87074.1 - 0.16 12.0 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 TGS domain ATP_bind_1 PF03029.17 PRP87074.1 - 0.66 9.7 3.7 16 5.2 0.0 3.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 PRP87074.1 - 0.77 9.3 4.6 1.1 8.9 0.0 3.2 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain Cullin PF00888.22 PRP87076.1 - 7.8e-193 642.5 21.5 9.5e-193 642.2 21.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PRP87076.1 - 7.4e-28 96.4 1.8 2.5e-27 94.7 1.8 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain MukF_M PF17192.4 PRP87076.1 - 0.004 16.9 5.3 0.73 9.6 0.9 3.0 2 0 0 2 2 2 2 MukF middle domain Mrpl_C PF18502.1 PRP87076.1 - 0.02 15.1 3.1 2.4 8.5 0.1 3.3 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain SLAIN PF15301.6 PRP87076.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 SLAIN motif-containing family ATP-synt_ab PF00006.25 PRP87077.1 - 1.1e-21 77.5 0.1 2.5e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 PRP87077.1 - 2e-05 24.9 1.4 0.00013 22.3 0.7 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATPase PF06745.13 PRP87077.1 - 0.0018 17.7 0.9 0.0039 16.6 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 PRP87077.1 - 0.0098 15.4 0.2 0.069 12.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 PRP87077.1 - 0.02 15.2 0.4 0.058 13.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PRP87077.1 - 0.023 14.9 0.2 0.081 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PRP87077.1 - 0.031 14.7 1.1 0.068 13.6 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 PRP87077.1 - 0.032 13.1 0.6 0.072 12.0 0.0 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 PRP87077.1 - 0.049 13.5 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea CobU PF02283.16 PRP87077.1 - 0.085 12.4 0.8 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase FtsK_SpoIIIE PF01580.18 PRP87077.1 - 0.098 12.0 0.3 0.24 10.7 0.3 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 PRP87077.1 - 0.1 12.5 0.1 0.32 10.9 0.1 1.9 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 PRP87077.1 - 0.14 11.9 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Com_YlbF PF06133.11 PRP87077.1 - 2.8 8.6 10.3 9.3 6.9 10.3 1.9 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Chibby PF14645.6 PRP87078.1 - 2.7e-16 60.0 0.2 3.4e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 Chibby family Macoilin PF09726.9 PRP87078.1 - 0.014 13.9 0.3 0.014 13.9 0.3 1.0 1 0 0 1 1 1 0 Macoilin family Ax_dynein_light PF10211.9 PRP87078.1 - 0.049 13.6 5.0 0.064 13.2 5.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain ZapB PF06005.12 PRP87078.1 - 1 9.8 11.1 5.2 7.6 11.1 1.9 1 1 0 1 1 1 0 Cell division protein ZapB DUF5595 PF18077.1 PRP87078.1 - 1.6 8.9 7.4 1.3 9.2 2.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DivIC PF04977.15 PRP87078.1 - 3 7.7 9.7 0.6 9.9 3.4 2.1 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 PRP87078.1 - 4 7.6 12.4 0.2 11.8 5.5 2.1 2 0 0 2 2 2 0 Basic region leucine zipper WD40 PF00400.32 PRP87079.1 - 1.1e-47 159.0 26.0 1.4e-10 41.5 0.4 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 PRP87079.1 - 1.1e-41 142.2 0.6 1.7e-41 141.5 0.6 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 PRP87079.1 - 8.8e-10 38.8 0.1 0.28 11.5 0.0 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PRP87079.1 - 5.3e-05 21.9 0.1 0.017 13.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 PRP87079.1 - 0.00045 19.0 2.6 0.27 9.8 0.1 3.4 3 2 0 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 PRP87079.1 - 0.0012 18.2 0.0 19 4.5 0.0 4.1 2 2 2 4 4 4 1 WD40-like domain eIF2A PF08662.11 PRP87079.1 - 0.0023 17.8 0.0 0.14 12.1 0.0 2.5 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PRP87079.1 - 0.025 13.6 0.0 9.4 5.1 0.0 3.5 2 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 PRP87079.1 - 0.15 11.1 0.1 0.76 8.7 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Snapin_Pallidin PF14712.6 PRP87080.1 - 0.014 15.8 14.3 0.11 12.9 11.1 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Fzo_mitofusin PF04799.13 PRP87080.1 - 0.032 13.8 6.9 0.039 13.5 6.9 1.1 1 0 0 1 1 1 0 fzo-like conserved region Med9 PF07544.13 PRP87080.1 - 0.05 13.7 12.0 0.087 12.9 12.0 1.4 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Cob_adeno_trans PF01923.18 PRP87080.1 - 0.052 13.7 1.2 0.063 13.4 1.2 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase ACCA PF03255.14 PRP87080.1 - 0.43 10.4 4.8 0.67 9.8 4.8 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Exo_endo_phos PF03372.23 PRP87081.1 - 0.091 12.3 0.0 0.58 9.6 0.0 2.1 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family cwf18 PF08315.12 PRP87082.1 - 1.5e-16 61.3 3.4 2.5e-16 60.6 3.4 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SIR4_SID PF16991.5 PRP87082.1 - 0.024 14.7 1.9 0.032 14.3 1.5 1.4 1 1 0 1 1 1 0 Sir4 SID domain MHC_II_beta PF00969.19 PRP87082.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain DUF1104 PF06518.11 PRP87082.1 - 0.66 10.4 6.0 0.19 12.1 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) SCO1-SenC PF02630.14 PRP87083.1 - 2.2e-46 157.1 0.0 3.1e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 PRP87083.1 - 7.4e-05 22.7 0.1 0.00021 21.2 0.0 1.8 2 1 1 3 3 3 1 AhpC/TSA family Redoxin PF08534.10 PRP87083.1 - 0.00065 19.4 0.0 0.064 13.0 0.0 2.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 PRP87083.1 - 0.083 13.2 0.1 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like PEPCK_N PF17297.2 PRP87083.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain HAD_2 PF13419.6 PRP87084.1 - 2.5e-25 89.6 0.0 3.6e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP87084.1 - 7.3e-15 55.8 0.1 6.1e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PRP87084.1 - 2e-05 25.1 0.0 3.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PRP87084.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_3 PF08282.12 PRP87084.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PRP87084.1 - 0.094 12.8 0.0 9.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CBM39 PF15886.5 PRP87085.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 1 0 1 1 1 0 Carbohydrate binding domain (family 32) CLZ PF16526.5 PRP87086.1 - 0.0012 19.2 2.2 0.0015 18.8 0.6 1.9 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SHE3 PF17078.5 PRP87086.1 - 0.0016 18.2 2.2 0.0025 17.6 2.2 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Phage_GPO PF05929.11 PRP87086.1 - 0.0028 17.3 0.1 0.0033 17.1 0.1 1.1 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase DUF3450 PF11932.8 PRP87086.1 - 0.01 15.1 1.9 0.014 14.7 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 PRP87086.1 - 0.013 15.8 2.0 0.063 13.6 1.9 2.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 PRP87086.1 - 0.02 15.0 3.6 0.03 14.5 3.6 1.2 1 0 0 1 1 1 0 Tropomyosin like THOC7 PF05615.13 PRP87086.1 - 0.049 13.9 3.1 0.079 13.2 3.1 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Fzo_mitofusin PF04799.13 PRP87086.1 - 0.054 13.0 0.3 0.076 12.6 0.3 1.3 1 0 0 1 1 1 0 fzo-like conserved region NPV_P10 PF05531.12 PRP87086.1 - 0.083 13.4 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CCDC-167 PF15188.6 PRP87086.1 - 0.32 11.4 4.9 0.52 10.7 4.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3552 PF12072.8 PRP87086.1 - 0.4 10.1 6.0 0.56 9.6 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Prefoldin PF02996.17 PRP87086.1 - 0.54 10.2 3.3 1.4 8.9 3.0 1.7 1 1 1 2 2 2 0 Prefoldin subunit XhlA PF10779.9 PRP87086.1 - 0.55 10.5 3.9 2 8.7 3.8 1.9 1 1 0 1 1 1 0 Haemolysin XhlA FemAB PF02388.16 PRP87086.1 - 0.7 8.7 2.7 1.1 8.0 2.7 1.2 1 0 0 1 1 1 0 FemAB family zf-TRAF_2 PF15965.5 PRP87088.1 - 1.2e-07 32.1 11.2 1.2e-07 32.1 11.2 1.8 2 0 0 2 2 2 1 TRAF-like zinc-finger zf-TRAF PF02176.18 PRP87088.1 - 7.2e-06 26.6 1.9 7.2e-06 26.6 1.9 3.5 2 1 2 4 4 4 1 TRAF-type zinc finger Tup_N PF08581.10 PRP87088.1 - 0.12 12.7 9.6 1.7 9.0 2.8 2.9 2 1 1 3 3 3 0 Tup N-terminal Exonuc_VII_L PF02601.15 PRP87088.1 - 0.21 11.1 1.2 0.22 11.0 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_MT_bd PF06657.13 PRP87088.1 - 0.25 11.8 8.1 2.2 8.8 0.2 2.7 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Sina PF03145.16 PRP87088.1 - 1.7 8.6 14.3 0.038 13.9 6.0 2.4 1 1 1 2 2 2 0 Seven in absentia protein family PKD_channel PF08016.12 PRP87089.1 - 2e-48 165.1 11.6 3.3e-48 164.4 11.6 1.4 1 0 0 1 1 1 1 Polycystin cation channel WD40 PF00400.32 PRP87089.1 - 6.6e-47 156.5 44.2 2.8e-06 28.0 0.1 14.5 14 0 0 14 14 14 11 WD domain, G-beta repeat Ank_2 PF12796.7 PRP87089.1 - 1.6e-28 99.1 3.2 1.4e-13 51.2 0.5 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP87089.1 - 1.4e-22 79.5 4.9 9.8e-10 38.5 0.0 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP87089.1 - 4.4e-21 75.0 4.4 6.8e-09 36.1 0.4 5.6 3 1 3 6 6 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87089.1 - 9.4e-19 65.6 4.7 0.00013 22.1 0.1 6.7 8 0 0 8 8 6 3 Ankyrin repeat Ank PF00023.30 PRP87089.1 - 9.3e-15 54.3 9.5 0.00028 21.2 0.2 5.7 6 0 0 6 6 5 3 Ankyrin repeat ANAPC4_WD40 PF12894.7 PRP87089.1 - 3.2e-11 43.4 8.7 0.34 11.2 0.1 9.5 6 3 3 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PRP87089.1 - 1.1e-09 38.2 1.4 8.1e-06 25.6 0.1 3.5 3 1 0 3 3 3 2 PQQ-like domain WD40_like PF17005.5 PRP87089.1 - 1.2e-08 34.6 10.5 0.037 13.4 0.1 5.4 2 1 3 6 6 6 3 WD40-like domain Nup160 PF11715.8 PRP87089.1 - 1.1e-07 30.9 11.2 0.16 10.6 0.0 7.4 5 3 3 8 8 8 3 Nucleoporin Nup120/160 PQQ_3 PF13570.6 PRP87089.1 - 2.8e-05 24.5 0.2 6.4 7.4 0.0 6.5 7 0 0 7 7 6 1 PQQ-like domain F-box-like PF12937.7 PRP87089.1 - 0.00027 20.8 1.5 0.00065 19.5 1.5 1.6 1 0 0 1 1 1 1 F-box-like Ion_trans PF00520.31 PRP87089.1 - 0.0027 17.0 28.8 0.016 14.4 28.8 2.2 1 1 0 1 1 1 1 Ion transport protein F-box PF00646.33 PRP87089.1 - 0.01 15.7 0.2 0.024 14.5 0.2 1.7 1 0 0 1 1 1 0 F-box domain Lebercilin PF15619.6 PRP87089.1 - 9.7 5.8 13.6 8 6.1 1.0 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CDC45 PF02724.14 PRP87091.1 - 3.4e-05 22.3 13.2 4.1e-05 22.1 13.2 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 PRP87091.1 - 0.00047 19.7 17.8 0.00061 19.3 17.8 1.2 1 0 0 1 1 1 1 SDA1 CDC27 PF09507.10 PRP87091.1 - 0.0018 17.7 12.2 0.0021 17.5 12.2 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1115 PF06544.12 PRP87091.1 - 0.0024 18.0 9.1 0.0098 16.0 9.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) RR_TM4-6 PF06459.12 PRP87091.1 - 0.0033 17.3 10.3 0.0044 16.9 10.3 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 PRP87091.1 - 0.0063 16.9 10.1 0.011 16.1 10.1 1.3 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 PRP87091.1 - 0.008 14.5 21.2 0.0094 14.2 21.2 1.0 1 0 0 1 1 1 1 Nop14-like family SpoIIP PF07454.11 PRP87091.1 - 0.012 15.1 7.8 0.014 14.9 7.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DARPP-32 PF05395.12 PRP87091.1 - 0.013 15.7 14.6 0.019 15.2 14.6 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 CobT PF06213.12 PRP87091.1 - 0.014 14.8 22.1 0.019 14.4 22.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sporozoite_P67 PF05642.11 PRP87091.1 - 0.014 13.5 6.9 0.017 13.2 6.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mpp10 PF04006.12 PRP87091.1 - 0.018 13.5 21.7 0.023 13.2 21.7 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 PRP87091.1 - 0.023 13.5 5.2 0.025 13.4 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CheX PF13690.6 PRP87091.1 - 0.023 14.9 0.1 0.051 13.7 0.1 1.7 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX RNA_pol_Rpc4 PF05132.14 PRP87091.1 - 0.025 15.0 5.3 0.034 14.6 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 PRP87091.1 - 0.027 13.2 5.1 0.031 13.1 5.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 PRP87091.1 - 0.028 15.4 3.0 0.028 15.4 3.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) DNA_pol_phi PF04931.13 PRP87091.1 - 0.037 12.1 25.5 0.046 11.8 25.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF4820 PF16091.5 PRP87091.1 - 0.042 13.2 4.7 0.056 12.8 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SGT1 PF07093.11 PRP87091.1 - 0.044 12.2 10.6 0.053 12.0 10.6 1.1 1 0 0 1 1 1 0 SGT1 protein CLN3 PF02487.17 PRP87091.1 - 0.074 12.1 0.2 0.095 11.7 0.2 1.1 1 0 0 1 1 1 0 CLN3 protein CPSF100_C PF13299.6 PRP87091.1 - 0.08 13.1 6.3 0.15 12.2 6.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 PRP87091.1 - 0.082 13.1 0.7 0.078 13.1 0.7 1.2 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.7 PRP87091.1 - 0.13 10.4 4.4 0.14 10.2 4.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4746 PF15928.5 PRP87091.1 - 0.14 11.6 16.9 0.21 11.0 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Connexin PF00029.19 PRP87091.1 - 0.21 11.3 5.4 0.3 10.8 5.4 1.3 1 0 0 1 1 1 0 Connexin AAA_11 PF13086.6 PRP87091.1 - 0.26 11.0 4.3 0.3 10.8 4.3 1.2 1 0 0 1 1 1 0 AAA domain DUF2151 PF10221.9 PRP87091.1 - 0.27 9.8 7.1 0.31 9.6 7.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Tim54 PF11711.8 PRP87091.1 - 0.35 9.6 14.9 0.48 9.1 14.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YABBY PF04690.13 PRP87091.1 - 0.36 11.4 2.7 0.59 10.7 2.7 1.2 1 0 0 1 1 1 0 YABBY protein DDRGK PF09756.9 PRP87091.1 - 0.36 10.4 21.1 0.52 9.9 21.1 1.3 1 0 0 1 1 1 0 DDRGK domain Serinc PF03348.15 PRP87091.1 - 0.37 9.7 1.5 0.47 9.3 1.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 PRP87091.1 - 0.44 8.4 7.6 0.56 8.1 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Membralin PF09746.9 PRP87091.1 - 0.51 9.3 1.3 0.66 9.0 1.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein Zip PF02535.22 PRP87091.1 - 0.67 9.1 5.4 0.84 8.8 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter MRNIP PF15749.5 PRP87091.1 - 1.1 10.0 10.1 2.6 8.8 9.7 1.9 2 0 0 2 2 1 0 MRN-interacting protein TRAP_alpha PF03896.16 PRP87091.1 - 1.1 8.3 13.5 1.6 7.8 13.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PTPRCAP PF15713.5 PRP87091.1 - 1.2 9.4 23.8 2.5 8.4 23.8 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF913 PF06025.12 PRP87091.1 - 1.4 7.9 9.8 1.8 7.4 9.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Cnd2 PF05786.14 PRP87091.1 - 1.4 7.5 15.9 2.3 6.8 15.9 1.4 1 0 0 1 1 1 0 Condensin complex subunit 2 tRNA_bind_2 PF13725.6 PRP87091.1 - 1.6 8.4 11.2 2.4 7.8 11.2 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain YL1 PF05764.13 PRP87091.1 - 1.6 8.8 28.3 2.6 8.1 28.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 PRP87091.1 - 2.1 7.6 23.6 0.32 10.3 19.2 1.7 2 0 0 2 2 2 0 BUD22 RP-C_C PF11800.8 PRP87091.1 - 3 7.9 12.0 0.8 9.8 7.8 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region RPN2_C PF18004.1 PRP87091.1 - 3.8 7.4 18.1 7.6 6.4 18.1 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2828 PF11443.8 PRP87091.1 - 4.2 5.3 9.1 5.4 5.0 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Di19_C PF14571.6 PRP87091.1 - 5.5 7.6 12.5 11 6.6 12.5 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal G0-G1_switch_2 PF15103.6 PRP87091.1 - 7.1 7.1 7.3 14 6.1 7.3 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 GNAT_acetyltr_2 PF13718.6 PRP87091.1 - 7.4 5.9 6.4 12 5.3 6.4 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Sigma70_ner PF04546.13 PRP87091.1 - 7.7 6.3 23.7 13 5.6 23.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2722 PF10846.8 PRP87091.1 - 7.8 5.3 12.5 11 4.8 12.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Merozoite_SPAM PF07133.11 PRP87091.1 - 7.8 6.4 39.9 12 5.8 39.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Roughex PF06020.11 PRP87091.1 - 8.4 5.4 14.7 11 5.0 14.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein NPR3 PF03666.13 PRP87091.1 - 8.7 5.0 12.2 11 4.6 12.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3408 PF11888.8 PRP87091.1 - 9.2 6.4 18.6 19 5.4 18.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) LCAT PF02450.15 PRP87093.1 - 4e-73 246.8 0.0 5.7e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 PRP87093.1 - 0.0079 15.7 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) EB1 PF03271.17 PRP87093.1 - 0.01 16.0 1.8 0.015 15.6 0.0 2.1 2 0 0 2 2 2 0 EB1-like C-terminal motif Lipase_2 PF01674.18 PRP87093.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Hydrolase_4 PF12146.8 PRP87093.1 - 0.16 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DPBB_1 PF03330.18 PRP87097.1 - 2.3e-11 43.8 0.1 3.3e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 PRP87097.1 - 0.022 14.6 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Barwin family Methyltransf_23 PF13489.6 PRP87098.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 PRP87101.1 - 1.8e-61 207.8 0.0 1.8e-61 207.8 0.0 3.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87101.1 - 9e-45 153.0 1.2 1.1e-43 149.4 0.0 2.6 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_6 PF13516.6 PRP87101.1 - 1.7e-20 71.3 16.1 2.4e-05 24.0 0.2 7.3 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 PRP87101.1 - 0.00026 21.3 4.0 0.0057 17.0 0.2 3.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP87101.1 - 0.0028 17.4 0.5 1.7 8.5 0.5 3.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 PRP87101.1 - 0.0043 17.4 0.4 61 4.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat Sod_Fe_N PF00081.22 PRP87101.1 - 0.12 12.9 1.5 0.36 11.3 0.1 2.6 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Lactamase_B_4 PF13691.6 PRP87102.1 - 1.3e-17 63.2 0.4 2.8e-17 62.1 0.1 1.8 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 PRP87102.1 - 1.7e-13 50.6 4.0 5.7e-12 45.6 0.3 3.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP87102.1 - 0.019 15.0 0.3 0.098 12.7 0.3 2.2 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 PRP87102.1 - 0.1 12.0 0.0 18 4.7 0.0 2.4 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain V-SNARE_C PF12352.8 PRP87103.1 - 0.00035 20.8 1.3 0.0013 19.0 0.4 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF3416 PF11896.8 PRP87103.1 - 0.022 15.1 0.3 0.05 13.9 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3416) TerB_C PF15615.6 PRP87103.1 - 0.028 14.7 0.8 0.045 14.0 0.8 1.4 1 0 0 1 1 1 0 TerB-C domain DUF1759 PF03564.15 PRP87103.1 - 0.044 13.7 0.9 6.9 6.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) TolA_bind_tri PF16331.5 PRP87103.1 - 0.12 12.5 3.8 0.79 9.8 0.1 2.7 2 1 1 3 3 3 0 TolA binding protein trimerisation Abhydrolase_1 PF00561.20 PRP87104.1 - 5.5e-23 81.9 0.1 5e-22 78.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP87104.1 - 8.4e-16 59.2 0.0 1.2e-15 58.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP87104.1 - 1.8e-14 53.6 0.1 8.4e-14 51.4 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 PRP87104.1 - 0.00029 19.6 0.0 0.0025 16.6 0.0 1.9 2 0 0 2 2 2 1 Ndr family DLH PF01738.18 PRP87104.1 - 0.00042 19.9 0.0 0.37 10.3 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PRP87104.1 - 0.0016 17.9 0.2 0.3 10.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF3530 PF12048.8 PRP87104.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Abhydrolase_4 PF08386.10 PRP87104.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein SnoaL_3 PF13474.6 PRP87104.1 - 0.083 13.1 0.1 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain V4R PF02830.18 PRP87105.1 - 2.4e-12 46.6 8.9 9.8e-09 35.1 0.3 2.6 2 0 0 2 2 2 2 V4R domain SpoIISB_antitox PF14185.6 PRP87105.1 - 0.045 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system Peptidase_M20 PF01546.28 PRP87109.1 - 6e-21 75.1 0.0 8.4e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PRP87109.1 - 4.9e-13 48.9 0.0 1.1e-12 47.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 PRP87109.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Ras PF00071.22 PRP87110.1 - 2.8e-13 49.8 0.0 1.2e-10 41.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 PRP87110.1 - 1.5e-11 44.6 0.0 4.7e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP87110.1 - 4.6e-07 29.4 0.0 2.9e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 PRP87110.1 - 0.0018 18.7 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 PRP87110.1 - 0.013 15.6 0.0 0.029 14.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 PRP87110.1 - 0.027 14.9 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PRP87110.1 - 0.055 13.4 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase Sigma54_activat PF00158.26 PRP87110.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 PRP87110.1 - 0.091 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 PRP87110.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Aldose_epim PF01263.20 PRP87111.1 - 8.2e-48 163.2 0.8 9.6e-48 163.0 0.8 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase_Tyr PF07714.17 PRP87112.1 - 2e-47 161.6 0.0 3.3e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87112.1 - 1.5e-46 159.0 0.0 2.3e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 PRP87112.1 - 2e-24 86.8 0.0 3.9e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP87112.1 - 3.2e-12 46.6 0.0 7.1e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Kdo PF06293.14 PRP87112.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP87112.1 - 0.006 15.4 0.0 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP87112.1 - 0.02 13.8 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PRP87112.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family UCH PF00443.29 PRP87113.1 - 5.2e-63 212.9 0.1 8.3e-63 212.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 PRP87113.1 - 1.3e-25 89.8 0.3 1e-15 58.1 0.1 2.5 2 0 0 2 2 2 2 DUSP domain UCH_1 PF13423.6 PRP87113.1 - 2.1e-22 80.2 2.6 5.7e-22 78.7 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PRP87113.1 - 2.5e-12 46.9 9.5 2.5e-12 46.9 9.5 3.2 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 PRP87113.1 - 0.0053 16.5 0.3 0.017 14.9 0.3 1.8 1 0 0 1 1 1 1 Variant UBP zinc finger PPR_2 PF13041.6 PRP87114.1 - 4.3e-23 81.2 0.7 5.6e-09 36.1 0.0 6.1 4 2 2 6 6 6 5 PPR repeat family PPR PF01535.20 PRP87114.1 - 2.2e-21 74.6 5.1 0.0024 18.0 0.0 7.3 7 1 0 7 7 7 5 PPR repeat PPR_3 PF13812.6 PRP87114.1 - 6.3e-15 55.0 0.6 6.9e-08 32.5 0.0 4.2 3 2 1 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP87114.1 - 9.6e-14 51.3 0.1 9.6e-10 38.2 0.1 2.8 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP87114.1 - 7.4e-08 32.0 0.0 0.045 13.5 0.0 4.3 4 0 0 4 4 4 2 PPR repeat Exog_C PF18026.1 PRP87114.1 - 0.00045 20.2 0.1 0.0018 18.3 0.1 2.1 1 0 0 1 1 1 1 Endo/exonuclease (EXOG) C-terminal domain Clathrin PF00637.20 PRP87114.1 - 0.0046 16.9 0.4 0.072 13.0 0.1 2.7 2 1 0 2 2 2 1 Region in Clathrin and VPS FTSW_RODA_SPOVE PF01098.19 PRP87114.1 - 0.023 13.7 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Cell cycle protein TPR_14 PF13428.6 PRP87114.1 - 0.082 13.8 0.1 38 5.5 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat ICL PF00463.21 PRP87115.1 - 1.5e-203 677.1 0.1 4.2e-120 401.7 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 PRP87115.1 - 6.6e-11 42.1 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Surp PF01805.20 PRP87116.1 - 7e-30 102.8 6.3 8.3e-16 57.7 0.3 2.5 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 PRP87116.1 - 5.5e-24 85.3 7.5 7.1e-15 55.5 0.0 2.6 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein ubiquitin PF00240.23 PRP87116.1 - 5.6e-14 51.7 0.1 1.1e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PRP87116.1 - 3.4e-05 23.6 0.1 0.00067 19.4 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP87116.1 - 9.4e-05 22.8 0.1 0.00046 20.6 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin-like domain zf_UBZ PF18439.1 PRP87116.1 - 0.00053 19.5 0.2 0.0012 18.4 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger UN_NPL4 PF11543.8 PRP87116.1 - 0.018 15.5 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf_C2H2_13 PF18508.1 PRP87116.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc finger domain Plexin_cytopl PF08337.12 PRP87116.1 - 0.063 11.9 0.0 0.09 11.4 0.0 1.1 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain NifU_N PF01592.16 PRP87117.1 - 2.9e-53 179.4 0.1 3.6e-53 179.1 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Tetraspanin PF00335.20 PRP87119.1 - 0.00094 19.0 6.5 0.00094 19.0 6.5 2.4 1 1 1 2 2 2 1 Tetraspanin family AIP3 PF03915.13 PRP87119.1 - 0.026 13.6 1.8 0.038 13.1 1.8 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 PRA1 PF03208.19 PRP87119.1 - 0.13 11.9 4.5 3.4 7.3 2.4 2.2 2 0 0 2 2 2 0 PRA1 family protein CD20 PF04103.15 PRP87119.1 - 1.3 9.1 7.9 2.8 8.0 7.9 1.7 1 1 0 1 1 1 0 CD20-like family Phage_holin_5_2 PF16079.5 PRP87119.1 - 2.1 8.8 10.4 8.5 6.8 1.3 3.2 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V EP400_N PF15790.5 PRP87120.1 - 0.014 14.3 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal SPO22 PF08631.10 PRP87120.1 - 0.031 13.8 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like PAS_8 PF13188.7 PRP87120.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS domain MLTR_LBD PF17765.1 PRP87121.1 - 0.032 14.4 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain PAS PF00989.25 PRP87121.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold NDUFB10 PF10249.9 PRP87121.1 - 0.11 13.0 1.0 0.13 12.7 0.0 1.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 DUF3005 PF11448.8 PRP87122.1 - 0.003 17.6 3.7 7.7 6.6 0.3 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3005) zf_CCCH_5 PF18384.1 PRP87122.1 - 0.044 13.9 91.4 1.5 9.0 0.0 14.8 20 0 0 20 20 20 0 Unkempt Zinc finger domain 1 (Znf1) PLA2_B PF01735.18 PRP87122.1 - 0.048 12.1 0.0 62 1.8 0.0 4.0 4 0 0 4 4 4 0 Lysophospholipase catalytic domain DUF5051 PF16473.5 PRP87122.1 - 0.35 10.8 4.5 56 3.7 0.1 4.0 4 0 0 4 4 4 0 3' exoribonuclease, RNase T-like Innate_immun PF12782.7 PRP87122.1 - 0.82 9.1 15.5 1.5 8.3 0.2 4.0 4 0 0 4 4 4 0 Invertebrate innate immunity transcript family CMV_1a PF12467.8 PRP87122.1 - 2 8.7 7.7 1.2e+02 3.0 0.2 5.3 5 2 1 6 6 6 0 Cucumber mosaic virus 1a protein family Antifungal_prot PF11402.8 PRP87122.1 - 2.1 8.7 80.2 0.51 10.6 1.2 11.5 8 5 5 13 13 13 0 Antifungal protein Suf PF05843.14 PRP87124.1 - 3.2e-15 56.9 15.0 0.0015 18.6 0.0 7.0 6 2 0 6 6 6 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 PRP87124.1 - 4.8e-12 45.6 9.8 4.6 8.3 0.0 10.1 9 2 2 11 11 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP87124.1 - 7.7e-08 32.7 1.0 1.3 9.5 0.0 6.1 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP87124.1 - 2.5e-07 30.9 1.5 0.34 11.2 0.3 5.8 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 PRP87124.1 - 3.1e-07 30.1 12.8 0.12 12.6 0.1 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP87124.1 - 4.1e-06 26.5 1.9 4.5 7.6 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 PRP87124.1 - 0.00013 21.2 12.6 0.0061 15.7 0.1 5.2 2 2 3 5 5 5 1 NRDE-2, necessary for RNA interference Mad3_BUB1_I PF08311.12 PRP87124.1 - 0.00067 19.6 18.0 2.9 7.9 0.2 7.8 6 3 1 7 7 7 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 PRP87124.1 - 0.0019 17.5 5.2 2.2 7.4 0.0 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP87124.1 - 0.0068 15.8 0.2 0.078 12.3 0.1 2.4 2 0 0 2 2 2 1 MalT-like TPR region RPN7 PF10602.9 PRP87124.1 - 0.007 16.1 0.1 0.075 12.7 0.1 2.8 3 0 0 3 3 3 1 26S proteasome subunit RPN7 mRNA_stabil PF13929.6 PRP87124.1 - 0.021 13.8 1.0 0.35 9.8 0.0 3.1 4 0 0 4 4 4 0 mRNA stabilisation TPR_6 PF13174.6 PRP87124.1 - 0.037 14.7 10.4 1.2e+02 3.7 0.1 7.0 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 PRP87124.1 - 0.11 12.7 0.3 5.7 7.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 PRP87124.1 - 9.8 6.7 10.7 16 6.0 0.0 6.0 7 0 0 7 7 5 0 PPR repeat Fip1 PF05182.13 PRP87125.1 - 1.6e-23 81.9 1.3 2.5e-23 81.3 1.3 1.3 1 0 0 1 1 1 1 Fip1 motif PIG-X PF08320.12 PRP87126.1 - 7.5e-28 97.9 1.2 4e-26 92.3 1.2 2.1 1 1 0 1 1 1 1 PIG-X / PBN1 ADH_zinc_N PF00107.26 PRP87127.1 - 8.4e-25 87.3 0.1 2e-24 86.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP87127.1 - 1.2e-16 62.0 0.1 3.2e-16 60.6 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SET PF00856.28 PRP87127.1 - 7.7e-11 42.7 0.1 1.7e-09 38.3 0.0 3.0 2 1 1 3 3 3 1 SET domain ADH_N PF08240.12 PRP87127.1 - 2.1e-10 40.5 0.0 2.1e-10 40.5 0.0 2.7 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain zf-C3HC4_2 PF13923.6 PRP87127.1 - 2.1e-06 27.5 22.0 2.1e-06 27.5 22.0 5.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP87127.1 - 2.4e-06 27.3 19.4 2.4e-06 27.3 19.4 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP87127.1 - 0.00014 21.6 24.3 0.00014 21.6 24.3 4.9 4 1 1 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP87127.1 - 0.00026 21.0 16.7 0.00026 21.0 16.7 4.6 4 0 0 4 4 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 PRP87127.1 - 0.0015 18.9 22.7 0.0015 18.9 22.7 4.9 4 0 0 4 4 3 1 Ring finger domain U-box PF04564.15 PRP87127.1 - 0.0028 17.8 0.7 0.01 16.0 0.0 2.3 2 0 0 2 2 2 1 U-box domain zf-RING_5 PF14634.6 PRP87127.1 - 0.0031 17.4 22.5 0.0031 17.4 22.5 4.5 4 0 0 4 4 3 1 zinc-RING finger domain TPR_7 PF13176.6 PRP87127.1 - 0.18 11.9 0.2 1.2 9.4 0.0 2.5 3 0 0 3 3 1 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 PRP87127.1 - 0.54 10.6 22.1 0.053 13.8 15.4 2.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Pkinase_Tyr PF07714.17 PRP87128.1 - 3.9e-39 134.5 0.0 6e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87128.1 - 2e-31 109.3 0.0 4.2e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP87128.1 - 3.8e-08 33.7 1.7 3.8e-08 33.7 1.7 2.1 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP87128.1 - 1.4e-06 28.5 28.0 0.0025 18.2 1.6 6.4 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP87128.1 - 7.7e-05 22.4 20.2 0.0028 17.4 0.7 5.5 6 0 0 6 6 6 3 Leucine rich repeat Kdo PF06293.14 PRP87128.1 - 0.038 13.3 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pentapeptide_3 PF13576.6 PRP87128.1 - 3.6 7.8 5.4 33 4.7 0.0 4.0 5 0 0 5 5 5 0 Pentapeptide repeats (9 copies) CLU PF13236.6 PRP87129.1 - 1.4e-37 129.7 0.0 4.3e-37 128.1 0.0 1.8 1 1 0 1 1 1 1 Clustered mitochondria PH PF00169.29 PRP87129.1 - 8.9e-16 58.3 0.4 2e-15 57.2 0.4 1.6 1 0 0 1 1 1 1 PH domain eIF3_p135 PF12807.7 PRP87129.1 - 0.00046 20.3 0.2 0.00089 19.3 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 PH_9 PF15410.6 PRP87129.1 - 0.002 18.5 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 PRP87129.1 - 0.0033 17.8 2.0 0.041 14.3 2.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 PRP87129.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_L34 PF00468.17 PRP87130.1 - 6e-15 54.9 6.2 8.6e-15 54.4 6.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 RST PF12174.8 PRP87130.1 - 0.06 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain UAA PF08449.11 PRP87131.1 - 5.7e-79 265.4 19.1 2.6e-78 263.3 19.1 1.8 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 PRP87131.1 - 0.002 17.5 0.7 0.002 17.5 0.7 3.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 PRP87131.1 - 0.0029 17.8 31.0 0.0033 17.6 7.9 3.9 4 0 0 4 4 4 3 EamA-like transporter family SLC35F PF06027.12 PRP87131.1 - 0.013 15.0 16.9 0.027 14.0 3.7 2.3 2 0 0 2 2 2 0 Solute carrier family 35 ApoB100_C PF12491.8 PRP87132.1 - 0.0051 16.8 1.9 2.1 8.4 0.2 2.6 2 0 0 2 2 2 2 Apolipoprotein B100 C terminal Shugoshin_N PF07558.11 PRP87132.1 - 0.016 15.1 2.5 1.5 8.7 1.0 2.8 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Pox_F11 PF04943.12 PRP87132.1 - 1 8.4 11.2 1.3 8.0 11.2 1.0 1 0 0 1 1 1 0 Poxvirus F11 protein V_ATPase_I PF01496.19 PRP87132.1 - 2.7 5.8 15.6 3.4 5.5 15.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SpoIISA_toxin PF14171.6 PRP87132.1 - 5.2 6.7 6.9 19 4.9 6.9 1.9 1 1 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system TPR_MLP1_2 PF07926.12 PRP87132.1 - 8.6 6.4 31.7 44 4.1 30.4 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pkinase_Tyr PF07714.17 PRP87134.1 - 6.3e-61 205.9 0.2 2.1e-59 200.9 0.2 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87134.1 - 8.2e-43 146.7 0.0 4.9e-41 140.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP87134.1 - 3.2e-41 138.9 98.9 7.1e-08 32.1 2.6 13.8 10 4 4 14 14 14 12 Leucine rich repeat LRR_4 PF12799.7 PRP87134.1 - 7.1e-40 134.3 94.3 6.2e-05 23.3 5.6 16.2 11 5 2 15 15 15 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP87134.1 - 1.4e-15 55.4 79.4 1.1 10.0 0.2 23.3 23 3 0 23 23 22 5 Leucine Rich Repeat LRR_6 PF13516.6 PRP87134.1 - 4.7e-13 48.0 85.5 0.35 11.0 0.1 22.0 24 0 0 24 24 24 5 Leucine Rich repeat Amnionless PF14828.6 PRP87134.1 - 0.0091 14.9 0.3 0.017 14.0 0.3 1.3 1 0 0 1 1 1 1 Amnionless LRR_5 PF13306.6 PRP87134.1 - 0.03 14.3 3.4 0.87 9.5 0.2 4.2 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) SKG6 PF08693.10 PRP87134.1 - 0.046 13.1 1.9 0.09 12.2 1.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Stevor PF17410.2 PRP87134.1 - 0.17 11.4 0.5 0.34 10.4 0.5 1.5 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LRRNT_2 PF08263.12 PRP87134.1 - 0.36 11.2 3.4 1 9.7 3.4 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Adeno_E3_CR2 PF02439.15 PRP87134.1 - 0.94 9.3 6.0 2.1 8.2 6.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 PRP87134.1 - 1 9.4 4.5 0.25 11.4 0.7 1.9 2 0 0 2 2 2 0 Podoplanin DUF1275 PF06912.11 PRP87135.1 - 8.5e-34 117.2 15.0 1e-33 116.9 15.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Fic PF02661.18 PRP87136.1 - 2.7e-07 31.4 0.1 1.4e-06 29.1 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family XRN_M PF17846.1 PRP87137.1 - 6.8e-126 420.8 0.0 1e-125 420.2 0.0 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 PRP87137.1 - 8.4e-94 313.5 0.0 1.6e-93 312.6 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 PRP87137.1 - 0.067 13.3 3.1 0.14 12.3 3.1 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF5526 PF17664.1 PRP87137.1 - 0.21 11.1 0.1 0.21 11.1 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5526) Lung_7-TM_R PF06814.13 PRP87140.1 - 6.1e-65 219.4 27.4 8.3e-65 218.9 27.4 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor MT-A70 PF05063.14 PRP87140.1 - 8.7e-37 126.7 0.0 1.8e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 MT-A70 ZZ PF00569.17 PRP87140.1 - 3.4e-26 90.8 55.2 4.7e-09 35.9 5.6 4.7 5 0 0 5 5 5 4 Zinc finger, ZZ type CHIPS PF11434.8 PRP87140.1 - 0.044 13.6 0.1 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 Chemotaxis-inhibiting protein CHIPS HECT PF00632.25 PRP87142.1 - 2.2e-60 204.8 0.0 4.4e-60 203.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 PRP87142.1 - 8.2e-19 67.9 0.4 3.6e-18 65.8 0.1 2.3 2 0 0 2 2 2 1 SPRY domain PH PF00169.29 PRP87142.1 - 8.9e-16 58.3 0.1 5.3e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 PRP87142.1 - 3.4e-07 30.6 0.9 1.2e-06 28.9 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 PRP87142.1 - 0.028 14.8 0.1 0.1 13.0 0.1 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.6 PRP87142.1 - 0.043 14.1 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain CNTF PF01110.17 PRP87142.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Ciliary neurotrophic factor PH_2 PF08458.10 PRP87142.1 - 0.1 12.9 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_13 PF16652.5 PRP87142.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Exo_endo_phos PF03372.23 PRP87143.1 - 7.2e-08 32.2 0.0 1.5e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PRP87143.1 - 0.004 17.0 0.2 4.3 7.2 0.0 3.0 3 0 0 3 3 3 2 Endonuclease-reverse transcriptase NuiA PF07924.11 PRP87143.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Amidinotransf PF02274.17 PRP87144.1 - 1.1e-91 307.5 0.4 1.1e-45 156.3 0.0 3.0 2 1 0 2 2 2 2 Amidinotransferase PAD_porph PF04371.15 PRP87144.1 - 0.00067 19.0 0.1 0.0055 16.0 0.0 2.6 4 0 0 4 4 4 1 Porphyromonas-type peptidyl-arginine deiminase Antiterm PF03589.13 PRP87144.1 - 0.092 13.1 0.0 2.8 8.4 0.0 2.8 2 0 0 2 2 2 0 Antitermination protein Herpes_gI PF01688.17 PRP87144.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Cortex-I_coil PF09304.10 PRP87144.1 - 0.6 10.3 3.6 0.46 10.7 1.7 1.7 2 0 0 2 2 2 0 Cortexillin I, coiled coil Pur_ac_phosph_N PF16656.5 PRP87147.1 - 1.1e-08 35.5 0.0 2.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PRA1 PF03208.19 PRP87147.1 - 0.026 14.2 2.1 0.027 14.1 0.1 1.8 1 1 1 2 2 2 0 PRA1 family protein RNA_pol_Rpb5_C PF01191.19 PRP87148.1 - 4.1e-34 116.3 1.4 5.6e-34 115.8 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 PRP87148.1 - 1.1e-23 83.6 0.4 2e-23 82.7 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain PTB PF08416.13 PRP87148.1 - 0.036 14.2 0.3 7.8 6.7 0.0 2.4 2 1 0 2 2 2 0 Phosphotyrosine-binding domain Mrr_cat PF04471.12 PRP87148.1 - 0.044 13.8 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease F-box PF00646.33 PRP87149.1 - 0.12 12.3 0.1 22 5.1 0.0 2.7 2 0 0 2 2 2 0 F-box domain CLN3 PF02487.17 PRP87149.1 - 2.2 7.2 6.3 3.4 6.6 6.3 1.2 1 0 0 1 1 1 0 CLN3 protein Ly49 PF08391.10 PRP87149.1 - 2.3 8.6 9.9 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region XRN_M PF17846.1 PRP87149.1 - 5 6.0 15.5 8 5.3 15.5 1.3 1 0 0 1 1 1 0 Xrn1 helical domain O-antigen_lig PF13425.6 PRP87149.1 - 9.9 4.8 8.1 16 4.1 8.1 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pkinase PF00069.25 PRP87150.1 - 3e-51 174.3 0.0 4.5e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87150.1 - 7.2e-17 61.5 0.0 1.1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LisH PF08513.11 PRP87150.1 - 0.0096 15.9 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 LisH APH PF01636.23 PRP87150.1 - 0.05 13.5 0.2 0.24 11.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family VRR_NUC PF08774.11 PRP87151.1 - 5.2e-22 78.0 0.0 1.7e-21 76.3 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain p450 PF00067.22 PRP87152.1 - 7.3e-84 282.1 0.0 8.4e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 5_3_exonuc_N PF02739.16 PRP87152.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Symplekin_C PF12295.8 PRP87152.1 - 0.12 12.4 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal NADHdh_A3 PF14987.6 PRP87153.1 - 0.088 13.1 0.1 2.1 8.7 0.0 2.2 2 1 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 p450 PF00067.22 PRP87154.1 - 4.1e-24 85.2 2.7 6.8e-16 58.1 0.7 2.0 1 1 1 2 2 2 2 Cytochrome P450 Acyl-CoA_dh_1 PF00441.24 PRP87155.1 - 1.2e-49 168.4 0.1 1.9e-49 167.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PRP87155.1 - 1.5e-30 106.2 0.2 2.7e-30 105.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PRP87155.1 - 4.4e-26 90.9 0.0 1.7e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PRP87155.1 - 1.4e-21 77.2 0.0 2.5e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain BPL_LplA_LipB PF03099.19 PRP87155.1 - 1.1e-08 35.0 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family HECT PF00632.25 PRP87156.1 - 4.8e-70 236.5 0.0 1e-69 235.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.6 PRP87156.1 - 3.7e-16 59.6 0.0 1.2e-15 58.0 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily SPRY PF00622.28 PRP87156.1 - 1.2e-13 51.2 0.1 3.7e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 SPRY domain zf-RanBP PF00641.18 PRP87156.1 - 6e-07 28.7 2.4 1.3e-06 27.6 2.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF913 PF06025.12 PRP87156.1 - 0.00067 18.8 0.4 0.0019 17.3 0.4 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Laminin_G_1 PF00054.23 PRP87156.1 - 0.00074 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 PRP87156.1 - 0.0022 18.5 0.0 0.0066 17.0 0.0 1.8 1 0 0 1 1 1 1 Laminin G domain Vps36-NZF-N PF16988.5 PRP87156.1 - 0.15 11.5 0.4 0.38 10.2 0.4 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SAC3_GANP PF03399.16 PRP87159.1 - 1.8e-72 244.2 2.4 1.8e-72 244.2 2.4 3.5 2 1 2 4 4 4 1 SAC3/GANP family Complex1_LYR_2 PF13233.6 PRP87160.1 - 4.8e-08 33.6 0.3 6.3e-08 33.3 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like LRR_6 PF13516.6 PRP87161.1 - 3.1e-13 48.6 43.8 0.024 14.6 0.0 15.0 17 0 0 17 17 17 6 Leucine Rich repeat LRR_4 PF12799.7 PRP87161.1 - 8.1e-11 42.0 28.8 0.0057 17.0 0.2 9.8 8 2 0 9 9 9 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP87161.1 - 3.2e-05 23.9 23.9 7.2 7.6 0.1 11.1 11 1 0 11 11 11 1 Leucine Rich Repeat SAM_Ste50p PF09235.10 PRP87161.1 - 0.19 12.0 12.4 28 5.1 0.1 6.6 5 3 1 6 6 6 0 Ste50p, sterile alpha motif LRR_8 PF13855.6 PRP87161.1 - 9.3 6.1 19.4 13 5.6 0.1 7.0 5 3 2 7 7 7 0 Leucine rich repeat Pkinase PF00069.25 PRP87162.1 - 2.3e-55 187.8 0.0 2.6e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87162.1 - 1.2e-27 96.8 0.0 1.4e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kp4 PF09044.10 PRP87162.1 - 0.035 14.2 0.1 0.084 13.0 0.1 1.6 1 0 0 1 1 1 0 Kp4 Chromadorea_ALT PF05535.12 PRP87162.1 - 0.094 12.9 0.5 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 Chromadorea ALT protein RIO1 PF01163.22 PRP87162.1 - 0.1 12.2 1.6 0.45 10.1 1.7 1.9 1 1 0 1 1 1 0 RIO1 family CH PF00307.31 PRP87163.1 - 3.5e-16 59.3 3.6 2.6e-10 40.5 0.0 3.8 3 0 0 3 3 3 2 Calponin homology (CH) domain DUF3455 PF11937.8 PRP87163.1 - 7.4e-11 42.7 0.4 0.00031 21.2 0.0 3.8 2 1 0 2 2 2 2 Protein of unknown function (DUF3455) WD40 PF00400.32 PRP87163.1 - 8e-05 23.3 1.0 1.4 9.9 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat SGL PF08450.12 PRP87163.1 - 0.0094 15.6 0.1 0.089 12.4 0.1 2.6 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region CAMSAP_CH PF11971.8 PRP87163.1 - 0.012 15.4 0.1 7.8 6.4 0.0 2.7 2 0 0 2 2 2 0 CAMSAP CH domain ANAPC4_WD40 PF12894.7 PRP87163.1 - 0.018 15.3 0.3 0.79 10.1 0.0 3.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP87163.1 - 0.022 14.1 0.0 0.05 12.9 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain PQQ_2 PF13360.6 PRP87163.1 - 0.11 12.1 1.7 0.21 11.1 0.5 2.0 1 1 1 2 2 2 0 PQQ-like domain Hira PF07569.11 PRP87163.1 - 1.2 8.8 11.9 0.85 9.3 0.2 4.2 4 1 0 4 4 4 0 TUP1-like enhancer of split GST_N PF02798.20 PRP87164.1 - 1.2e-15 57.5 0.0 2.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP87164.1 - 2.1e-11 44.0 0.0 3.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP87164.1 - 8.4e-09 35.5 0.0 1.7e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP87164.1 - 2.8e-08 33.8 0.0 1.3e-07 31.8 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PRP87164.1 - 1.5e-06 28.4 0.0 2.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP87164.1 - 5.9e-06 26.2 0.0 3.5e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Peptidase_M1 PF01433.20 PRP87165.1 - 3.7e-34 118.2 2.3 5.5e-34 117.6 2.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PRP87165.1 - 4.3e-10 40.1 0.0 1.9e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 PRP87165.1 - 0.00017 21.9 1.3 0.016 15.6 0.0 3.5 4 0 0 4 4 4 1 HEAT repeats DUF3458 PF11940.8 PRP87165.1 - 0.00023 21.5 0.0 0.00079 19.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Stimulus_sens_1 PF13756.6 PRP87165.1 - 0.0098 16.5 0.1 0.032 14.8 0.1 1.9 1 0 0 1 1 1 1 Stimulus-sensing domain RTTN_N PF14726.6 PRP87165.1 - 0.079 13.8 0.1 0.3 11.9 0.1 2.0 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning DUF5339 PF17274.2 PRP87165.1 - 0.12 13.3 0.4 0.33 11.9 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5339) TAFII55_N PF04658.13 PRP87166.1 - 1.1e-27 96.7 0.1 1.1e-27 96.7 0.1 3.5 3 1 0 3 3 3 1 TAFII55 protein conserved region SRP-alpha_N PF04086.13 PRP87166.1 - 0.11 12.5 16.7 0.21 11.5 16.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LYRIC PF15686.5 PRP87166.1 - 1.5 8.3 27.2 2.6 7.5 27.2 1.3 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Allexi_40kDa PF05549.11 PRP87166.1 - 7.8 5.9 7.7 0.14 11.7 0.4 1.8 2 1 1 3 3 3 0 Allexivirus 40kDa protein Pterin_bind PF00809.22 PRP87168.1 - 2.9e-84 282.5 0.0 4.4e-84 282.0 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 PRP87168.1 - 5.7e-33 113.8 0.0 1.3e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 PRP87168.1 - 2.4e-24 86.0 0.1 1.5e-23 83.4 0.2 2.4 3 0 0 3 3 3 1 Dihydroneopterin aldolase EF-hand_1 PF00036.32 PRP87173.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 EF hand NPL PF17800.1 PRP87174.1 - 9.1e-13 48.7 0.1 9.1e-13 48.7 0.1 2.2 2 1 0 2 2 2 1 Nucleoplasmin-like domain zf-C2H2 PF00096.26 PRP87174.1 - 0.0011 19.4 0.5 0.0033 17.8 0.5 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP87174.1 - 0.0012 19.4 0.4 0.003 18.3 0.4 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger Nucleoplasmin PF03066.15 PRP87174.1 - 0.09 13.3 0.1 0.2 12.2 0.1 1.5 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain CENP-B_dimeris PF09026.10 PRP87174.1 - 3.1 8.2 7.2 6.5 7.2 7.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ECM1 PF05782.11 PRP87174.1 - 3.8 6.3 16.8 5.3 5.9 16.8 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) PH PF00169.29 PRP87175.1 - 3.7e-06 27.4 0.7 8.1e-06 26.3 0.7 1.5 1 0 0 1 1 1 1 PH domain DUF1769 PF08588.10 PRP87177.1 - 1.7e-17 63.4 0.4 6.1e-17 61.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) DUF3376 PF11856.8 PRP87177.1 - 0.88 8.5 2.2 1.2 8.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) PhyH PF05721.13 PRP87179.1 - 5.8e-16 59.4 0.4 1.3e-15 58.3 0.4 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HEAT_2 PF13646.6 PRP87179.1 - 5.9e-15 55.4 2.2 3.1e-07 30.7 0.2 3.5 1 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 PRP87179.1 - 0.00066 20.1 1.0 0.53 11.1 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT PF02985.22 PRP87179.1 - 0.035 14.3 0.3 9.6 6.8 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat V-set PF07686.17 PRP87179.1 - 0.079 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin V-set domain OPT PF03169.15 PRP87181.1 - 2.6e-122 409.5 33.4 3.8e-122 409.0 33.4 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2613 PF11021.8 PRP87181.1 - 0.21 11.7 1.4 1.3 9.2 1.4 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Pkinase_Tyr PF07714.17 PRP87182.1 - 1.2e-40 139.4 0.3 2e-40 138.7 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87182.1 - 7.7e-30 104.1 0.1 1.3e-29 103.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP87182.1 - 1.7e-06 28.4 7.1 7.5e-06 26.4 7.1 2.2 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_8 PF13855.6 PRP87182.1 - 6e-05 22.7 0.3 1.9 8.3 0.3 4.2 2 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 PRP87182.1 - 0.00037 20.3 1.2 1.2 9.4 0.4 5.2 5 0 0 5 5 5 1 Leucine Rich repeat Kinase-like PF14531.6 PRP87182.1 - 0.0024 17.2 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRR_4 PF12799.7 PRP87182.1 - 0.0034 17.8 6.6 18 5.9 0.0 5.6 5 1 1 6 6 5 0 Leucine Rich repeats (2 copies) Kdo PF06293.14 PRP87182.1 - 0.0056 16.1 0.1 0.0098 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Insulin_TMD PF17870.1 PRP87182.1 - 0.026 14.6 1.6 0.073 13.1 1.6 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment SIT PF15330.6 PRP87182.1 - 0.03 14.7 0.0 2.6 8.5 0.0 2.6 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT SKG6 PF08693.10 PRP87182.1 - 1.6 8.2 4.3 3.2 7.2 4.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pentapeptide_4 PF13599.6 PRP87183.1 - 0.12 12.6 1.1 1.9 8.7 0.2 2.3 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Lipase_GDSL_2 PF13472.6 PRP87184.1 - 0.00034 21.1 0.0 0.00057 20.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 PRP87184.1 - 0.15 12.1 0.0 2.6 8.2 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family TBCC_N PF16752.5 PRP87185.1 - 0.35 11.3 2.2 0.38 11.2 0.5 1.8 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Pkinase_Tyr PF07714.17 PRP87186.1 - 6.5e-60 202.6 1.8 1.1e-59 201.9 1.8 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RasGEF PF00617.19 PRP87186.1 - 2.3e-43 148.5 0.6 8.3e-43 146.6 0.6 2.1 1 0 0 1 1 1 1 RasGEF domain Pkinase PF00069.25 PRP87186.1 - 2.5e-39 135.3 0.7 5.1e-39 134.2 0.7 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP87186.1 - 2.3e-09 37.7 1.6 6.5e-09 36.2 1.6 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif RIO1 PF01163.22 PRP87186.1 - 0.00014 21.6 0.6 0.00032 20.4 0.6 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PRP87186.1 - 0.00014 21.3 0.1 0.00032 20.1 0.1 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP87186.1 - 0.00057 19.3 1.6 0.0012 18.3 1.6 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 PRP87186.1 - 0.017 14.8 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RasGEF_N PF00618.20 PRP87186.1 - 0.021 15.1 0.8 0.44 10.8 0.8 2.8 1 1 0 1 1 1 0 RasGEF N-terminal motif APH PF01636.23 PRP87186.1 - 0.045 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FUR PF01475.19 PRP87186.1 - 0.049 13.8 0.1 0.17 12.0 0.1 1.9 1 0 0 1 1 1 0 Ferric uptake regulator family DER1 PF04511.15 PRP87186.1 - 0.066 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Der1-like family Syndecan PF01034.20 PRP87186.1 - 0.19 11.7 0.5 0.41 10.6 0.5 1.5 1 0 0 1 1 1 0 Syndecan domain LAG1-DNAbind PF09271.11 PRP87188.1 - 1.8e-09 38.4 0.0 0.15 12.7 0.0 3.6 3 0 0 3 3 3 3 LAG1, DNA binding RR_TM4-6 PF06459.12 PRP87189.1 - 0.68 9.7 7.0 0.89 9.3 7.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MA3 PF02847.17 PRP87190.1 - 7.5e-18 64.6 0.4 5.5e-17 61.8 0.0 2.5 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 PRP87190.1 - 1.4e-15 57.5 0.2 3.2e-15 56.3 0.2 1.6 1 0 0 1 1 1 1 MIF4G domain SH3_2 PF07653.17 PRP87190.1 - 0.07 12.8 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain TMEM214 PF10151.9 PRP87190.1 - 8.3 4.7 9.8 1.1 7.7 2.1 2.7 3 0 0 3 3 3 0 TMEM214, C-terminal, caspase 4 activator Pkinase PF00069.25 PRP87191.1 - 4.9e-59 199.8 0.0 6.9e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87191.1 - 1.5e-45 155.6 0.0 2.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP87191.1 - 0.00093 18.6 0.0 0.0021 17.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like FERM_f0 PF16511.5 PRP87191.1 - 0.0018 18.6 0.0 0.005 17.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Pkinase_fungal PF17667.1 PRP87191.1 - 0.0037 16.1 2.1 0.11 11.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase PBD PF00786.28 PRP87191.1 - 0.0075 16.6 0.2 0.026 14.9 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Rad60-SLD PF11976.8 PRP87191.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Seadorna_VP7 PF07387.11 PRP87191.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1356 PF07092.12 PRP87191.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) SOG2 PF10428.9 PRP87191.1 - 0.7 9.0 12.4 1.2 8.3 12.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Rrn6 PF10214.9 PRP87191.1 - 4.6 5.6 15.0 7 5.0 15.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BBL5 PF07289.11 PRP87192.1 - 8.4e-98 327.5 0.0 9.8e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein bPH_3 PF14470.6 PRP87192.1 - 1.1e-05 25.8 0.0 0.0039 17.5 0.0 2.8 2 1 1 3 3 3 2 Bacterial PH domain Vps36_ESCRT-II PF11605.8 PRP87192.1 - 0.0047 17.1 0.5 5.5 7.2 0.0 3.0 3 0 0 3 3 3 2 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.13 PRP87192.1 - 0.0076 16.4 3.9 0.15 12.2 0.0 2.7 3 0 0 3 3 3 2 Regulator of volume decrease after cellular swelling PH PF00169.29 PRP87193.1 - 1.4e-08 35.2 4.1 2e-08 34.7 0.1 3.0 3 1 0 3 3 3 1 PH domain PH_9 PF15410.6 PRP87193.1 - 1.2e-05 25.6 0.2 0.0046 17.3 0.2 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain WW PF00397.26 PRP87193.1 - 2.8e-05 24.1 2.3 8e-05 22.6 2.3 1.7 1 0 0 1 1 1 1 WW domain DUF2459 PF09601.10 PRP87193.1 - 0.0033 17.3 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2459) PH_11 PF15413.6 PRP87193.1 - 0.031 14.7 0.2 0.18 12.2 0.2 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain DAO PF01266.24 PRP87194.1 - 1.7e-60 205.5 0.0 2.9e-60 204.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP87194.1 - 6.6e-05 23.1 0.1 0.00043 20.5 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PRP87194.1 - 0.0011 19.0 0.1 0.0033 17.4 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 PRP87194.1 - 0.0046 16.2 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 PRP87194.1 - 0.017 14.4 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 PRP87194.1 - 0.026 13.1 0.0 0.054 12.0 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.18 PRP87194.1 - 0.095 13.0 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain ISN1 PF06437.11 PRP87194.1 - 0.15 10.9 0.2 0.24 10.3 0.2 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Lycopene_cycl PF05834.12 PRP87194.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein RPN1_RPN2_N PF17781.1 PRP87199.1 - 1.1e-104 350.2 2.6 1.9e-104 349.4 1.9 1.8 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 PRP87199.1 - 3.6e-28 97.3 0.0 7.1e-28 96.4 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 PRP87199.1 - 4.6e-27 93.0 21.6 4.1e-05 23.8 0.8 8.7 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 PRP87199.1 - 3.4e-11 43.4 0.6 0.00099 19.5 0.0 4.2 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 PRP87199.1 - 0.014 15.6 0.5 9.5 6.8 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat eIF3_subunit PF08597.10 PRP87199.1 - 4.6 7.1 18.9 23 4.8 14.0 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF4515 PF14988.6 PRP87200.1 - 0.0073 16.2 41.4 0.0073 16.2 41.4 3.1 1 1 2 3 3 3 1 Domain of unknown function (DUF4515) DUF3437 PF11919.8 PRP87200.1 - 1 9.3 4.5 0.52 10.3 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3437) Sortilin-Vps10 PF15902.5 PRP87201.1 - 8.4e-32 110.5 0.1 1.7e-30 106.2 0.1 2.2 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PRP87201.1 - 4.9e-23 82.3 0.3 7.3e-23 81.8 0.3 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 PRP87201.1 - 0.0022 17.7 12.0 9.4 6.7 0.3 6.0 5 0 0 5 5 5 2 BNR/Asp-box repeat VCBS PF13517.6 PRP87201.1 - 0.41 11.3 3.2 16 6.2 0.1 3.2 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Arf PF00025.21 PRP87202.1 - 8.1e-58 194.7 0.0 1.2e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 PRP87202.1 - 5.9e-11 42.1 0.9 7.5e-08 31.9 0.4 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PRP87202.1 - 8.8e-11 42.1 0.1 2.9e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP87202.1 - 1.6e-10 40.7 0.0 2.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PRP87202.1 - 3.3e-09 36.6 0.0 5.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 PRP87202.1 - 9.6e-07 28.4 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP87202.1 - 0.0013 18.8 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 PRP87202.1 - 0.016 14.5 0.0 0.039 13.3 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Phospholip_B PF04916.13 PRP87203.1 - 3.5e-132 441.7 7.0 4.7e-132 441.3 7.0 1.1 1 0 0 1 1 1 1 Phospholipase B Pkinase_Tyr PF07714.17 PRP87204.1 - 1.1e-99 332.9 0.0 7.4e-51 172.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 PRP87204.1 - 2.6e-94 315.5 0.0 2.2e-49 168.2 0.0 3.4 3 0 0 3 3 3 2 Protein kinase domain Ank_2 PF12796.7 PRP87204.1 - 1.9e-43 146.9 11.8 2.8e-11 43.9 0.0 6.5 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87204.1 - 2.8e-39 133.0 4.7 3.1e-07 30.8 0.0 8.1 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP87204.1 - 9.1e-31 105.5 1.2 2.2e-06 27.8 0.0 8.4 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87204.1 - 6.8e-29 96.7 6.1 0.0038 17.6 0.1 10.5 11 0 0 11 11 11 6 Ankyrin repeat Ank PF00023.30 PRP87204.1 - 6.7e-27 92.7 15.7 2.5e-05 24.5 0.2 10.1 10 0 0 10 10 9 5 Ankyrin repeat SAM_1 PF00536.30 PRP87204.1 - 2.9e-12 46.8 3.2 1.8e-10 41.1 0.3 2.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP87204.1 - 1e-09 38.3 2.2 4.3e-08 33.2 0.2 3.1 3 0 0 3 3 2 1 SAM domain (Sterile alpha motif) APH PF01636.23 PRP87204.1 - 0.0066 16.4 0.2 3.1 7.6 0.1 3.7 2 2 2 4 4 4 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP87204.1 - 0.029 14.0 0.3 0.15 11.6 0.0 2.4 3 0 0 3 3 3 0 RIO1 family PSP PF04046.16 PRP87204.1 - 0.039 13.8 0.2 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 PSP SAM_KSR1 PF13543.6 PRP87204.1 - 0.097 12.8 4.7 0.93 9.6 0.6 2.8 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Pkinase_fungal PF17667.1 PRP87204.1 - 0.44 9.3 6.1 0.042 12.6 0.3 2.3 2 1 0 2 2 2 0 Fungal protein kinase Ras PF00071.22 PRP87205.1 - 6e-41 139.7 0.0 9.5e-41 139.1 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP87205.1 - 6.1e-12 45.8 0.0 1.3e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LBP_BPI_CETP_C PF02886.17 PRP87206.1 - 1.1e-35 123.3 0.0 2.2e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain LBP_BPI_CETP PF01273.25 PRP87206.1 - 1.7e-18 66.8 1.2 2.7e-18 66.1 1.2 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain DUF4403 PF14356.6 PRP87206.1 - 0.0033 16.1 0.0 0.0048 15.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4403) JHBP PF06585.11 PRP87206.1 - 0.064 12.4 0.2 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) Ints3 PF10189.9 PRP87206.1 - 0.11 11.7 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Integrator complex subunit 3 Pkinase PF00069.25 PRP87207.1 - 1.3e-45 155.9 0.0 2.1e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87207.1 - 6.8e-43 146.8 0.0 1.6e-42 145.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 PRP87207.1 - 2.4e-22 79.4 25.4 5.3e-22 78.2 24.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily PH PF00169.29 PRP87207.1 - 4.2e-09 36.9 0.1 1.5e-08 35.1 0.1 2.0 1 0 0 1 1 1 1 PH domain SH2 PF00017.24 PRP87207.1 - 2.1e-08 34.1 0.2 5.1e-08 32.9 0.2 1.7 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 PRP87207.1 - 0.028 14.3 0.0 0.075 13.0 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAD_binding_3 PF01494.19 PRP87208.1 - 1.5e-16 60.6 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 PRP87208.1 - 1.1e-10 41.7 0.0 4.2e-05 23.3 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP87208.1 - 1e-05 25.0 0.2 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PRP87208.1 - 3.7e-05 23.3 0.2 6.5e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP87208.1 - 0.00057 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 PRP87208.1 - 0.0017 17.3 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 PRP87208.1 - 0.0027 16.8 0.7 0.013 14.6 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 PRP87208.1 - 0.0033 16.5 2.3 0.18 10.8 2.3 2.9 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 PRP87208.1 - 0.0043 16.3 0.0 0.0074 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 PRP87208.1 - 0.0063 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 PRP87208.1 - 0.016 14.3 0.2 0.032 13.3 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Bac_thur_toxin PF01338.18 PRP87208.1 - 0.054 12.9 0.1 0.094 12.2 0.1 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin ADH_N PF08240.12 PRP87209.1 - 2.9e-25 88.3 8.4 2.9e-25 88.3 8.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PRP87209.1 - 2.2e-22 79.4 0.0 3.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP87209.1 - 2.6e-06 28.5 0.0 3.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PRP87209.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 PRP87209.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 PRP87209.1 - 0.00018 20.9 0.2 0.0003 20.2 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 PRP87209.1 - 0.035 14.5 0.0 0.07 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 PRP87209.1 - 0.1 12.3 0.2 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TIG PF01833.24 PRP87210.1 - 4.8e-129 420.7 427.5 2e-10 40.6 8.0 32.7 29 3 4 33 33 30 28 IPT/TIG domain Pkinase_Tyr PF07714.17 PRP87210.1 - 1.6e-69 234.1 0.0 5e-69 232.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PI3Ka PF00613.20 PRP87210.1 - 1.2e-51 174.7 1.2 2e-51 174.0 1.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.25 PRP87210.1 - 2.5e-48 164.8 0.0 6e-48 163.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain PI3_PI4_kinase PF00454.27 PRP87210.1 - 1.3e-47 162.7 0.2 7.7e-46 156.9 0.2 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 PRP87210.1 - 2.1e-32 112.0 0.1 6.7e-32 110.3 0.1 2.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Exo_endo_phos PF03372.23 PRP87210.1 - 3.8e-06 26.6 0.0 1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 PRP87210.1 - 0.00021 21.0 6.9 0.001 18.8 0.5 3.7 2 1 3 5 5 5 3 Leucine rich repeat PAN_4 PF14295.6 PRP87210.1 - 0.00066 19.5 1.4 0.0038 17.1 1.4 2.3 1 0 0 1 1 1 1 PAN domain LRR_4 PF12799.7 PRP87210.1 - 0.00073 19.9 5.0 0.022 15.2 0.2 3.7 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 PRP87210.1 - 0.00085 18.2 0.0 0.0014 17.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP87210.1 - 0.002 17.5 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Exo_endo_phos_2 PF14529.6 PRP87210.1 - 0.071 12.9 0.1 0.61 9.9 0.1 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase LRR_1 PF00560.33 PRP87210.1 - 2.6 8.9 5.4 2.6e+02 2.9 0.1 5.2 4 0 0 4 4 3 0 Leucine Rich Repeat Pkinase PF00069.25 PRP87212.1 - 1.4e-74 250.8 0.1 1.8e-74 250.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87212.1 - 2.3e-42 145.1 0.1 3.1e-42 144.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP87212.1 - 2e-07 30.6 0.0 9.6e-07 28.4 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 PRP87212.1 - 1.4e-05 24.6 0.2 2.6e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP87212.1 - 7.1e-05 21.9 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP87212.1 - 0.0035 17.3 0.5 0.018 14.9 0.7 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP87212.1 - 0.0045 16.6 0.7 0.01 15.5 0.7 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF3104 PF11302.8 PRP87212.1 - 0.2 11.4 0.0 0.72 9.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) MORN PF02493.20 PRP87213.1 - 1.1e-36 122.5 54.1 3.2e-08 33.0 2.8 9.0 10 0 0 10 10 10 7 MORN repeat F-box-like PF12937.7 PRP87213.1 - 2.7e-11 43.2 0.2 4.4e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP87213.1 - 1.4e-09 37.6 0.3 2.5e-09 36.8 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP87213.1 - 0.00091 19.1 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 F-box NADH_B2 PF14813.6 PRP87213.1 - 3.5 7.5 7.3 9 6.2 0.2 3.5 1 1 2 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 PQ-loop PF04193.14 PRP87214.1 - 2.7e-16 59.1 27.0 3.8e-10 39.4 5.3 3.6 3 1 1 4 4 4 2 PQ loop repeat DUF1689 PF07954.11 PRP87214.1 - 0.058 13.8 0.6 0.56 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) IQ PF00612.27 PRP87215.1 - 1.3e-06 27.7 0.0 4.4e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif PP2C PF00481.21 PRP87216.1 - 6.7e-60 202.9 0.2 9.1e-60 202.5 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Chitin_bind_1 PF00187.19 PRP87216.1 - 2.3e-06 28.0 22.1 2.3e-06 28.0 22.1 3.9 3 1 0 3 3 3 1 Chitin recognition protein PP2C_2 PF13672.6 PRP87216.1 - 6.7e-06 25.9 0.4 1e-05 25.3 0.4 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SLT PF01464.20 PRP87216.1 - 1.9e-05 24.3 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 PRP87216.1 - 0.00061 20.0 4.4 0.0032 17.7 4.4 2.2 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family TMEM119 PF15724.5 PRP87217.1 - 0.099 12.7 0.2 0.1 12.6 0.2 1.1 1 0 0 1 1 1 0 TMEM119 family Spc7 PF08317.11 PRP87219.1 - 0.0048 15.8 19.1 0.0048 15.8 19.1 6.3 3 1 4 7 7 7 4 Spc7 kinetochore protein Rab5-bind PF09311.11 PRP87219.1 - 0.016 14.6 0.1 0.016 14.6 0.1 6.1 3 2 2 5 5 5 0 Rabaptin-like protein ERM PF00769.19 PRP87219.1 - 4.2 7.1 151.9 0.11 12.3 29.6 5.8 3 2 2 5 5 5 0 Ezrin/radixin/moesin family Glycos_transf_1 PF00534.20 PRP87220.1 - 5.6e-29 100.9 0.0 2.7e-28 98.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PRP87220.1 - 2.7e-14 53.5 0.8 4.4e-14 52.8 0.2 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 PRP87220.1 - 2.1e-11 44.4 0.0 6.3e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PRP87220.1 - 6.8e-05 23.4 0.1 0.00014 22.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 PRP87220.1 - 0.00096 19.5 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alg14 PF08660.11 PRP87220.1 - 0.0044 17.0 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TrmO PF01980.16 PRP87221.1 - 8.3e-35 119.6 0.0 2.3e-34 118.1 0.0 1.8 1 1 0 1 1 1 1 tRNA-methyltransferase O Fungal_trans_2 PF11951.8 PRP87221.1 - 0.097 11.5 0.1 0.15 10.8 0.1 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain zf-CCHH PF10283.9 PRP87222.1 - 1.4e-12 47.4 8.7 2.6e-12 46.5 8.7 1.5 1 0 0 1 1 1 1 PBZ domain PARP PF00644.20 PRP87222.1 - 1.7e-09 37.6 0.4 1.4e-06 28.0 0.3 2.6 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain TMEM18 PF14770.6 PRP87223.1 - 4.1e-32 110.7 9.0 4.7e-32 110.5 9.0 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 FtsX PF02687.21 PRP87223.1 - 0.67 10.5 7.6 2.2 8.8 7.5 1.8 1 1 0 1 1 1 0 FtsX-like permease family DHHC PF01529.20 PRP87223.1 - 7.6 6.6 9.7 81 3.3 9.4 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Radial_spoke_3 PF06098.11 PRP87224.1 - 1.2e-95 320.0 21.7 1.2e-95 320.0 21.7 2.1 1 1 1 2 2 2 1 Radial spoke protein 3 Homoserine_dh PF00742.19 PRP87226.1 - 7.3e-43 146.5 0.0 1.1e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 PRP87226.1 - 1.5e-05 25.7 0.1 0.052 14.2 0.0 2.5 2 0 0 2 2 2 2 Homoserine dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 PRP87226.1 - 0.0036 17.0 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DXP_reductoisom PF02670.16 PRP87226.1 - 0.081 13.6 0.1 3.8 8.2 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase HC2 PF07382.11 PRP87227.1 - 4.6e-05 23.6 17.7 6e-05 23.2 17.7 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Nucleo_P87 PF07267.11 PRP87227.1 - 0.063 12.1 11.5 0.07 12.0 11.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CPSF100_C PF13299.6 PRP87227.1 - 2 8.6 7.3 2.6 8.2 7.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AAA_33 PF13671.6 PRP87228.1 - 1.5e-12 47.8 0.0 2.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP87228.1 - 0.0023 18.5 0.0 0.0032 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP87228.1 - 0.0063 15.8 0.1 0.018 14.3 0.0 1.8 2 1 0 2 2 2 1 Zeta toxin KTI12 PF08433.10 PRP87228.1 - 0.014 14.8 0.4 0.1 12.0 0.4 1.9 1 1 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 PRP87228.1 - 0.017 15.7 0.0 0.023 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 PRP87228.1 - 0.019 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 PRP87228.1 - 0.023 14.4 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 PRP87228.1 - 0.028 14.7 0.1 0.21 11.8 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 PRP87228.1 - 0.046 13.4 0.1 0.2 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 PRP87228.1 - 0.046 12.8 0.1 0.29 10.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 PRP87228.1 - 0.057 13.7 0.0 0.092 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 PRP87228.1 - 0.091 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DnaB_C PF03796.15 PRP87228.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_5 PF07728.14 PRP87228.1 - 0.14 12.2 0.0 0.39 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FSAP_sig_propep PF03032.15 PRP87230.1 - 1 9.4 0.1 1 9.4 0.1 4.9 5 0 0 5 5 5 0 Frog skin active peptide family signal and propeptide YqgF PF14639.6 PRP87230.1 - 3.7 7.3 8.8 2.8 7.7 1.8 2.5 2 1 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 zf_CCCH_4 PF18345.1 PRP87231.1 - 4.3e-09 36.1 24.8 9.1e-06 25.6 2.9 3.6 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH PF00642.24 PRP87231.1 - 4.9e-09 35.9 20.1 6.9e-05 22.6 3.3 3.5 2 1 1 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 PRP87231.1 - 2.5e-07 30.9 9.8 9.4e-06 25.8 3.1 2.9 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 PRP87231.1 - 2.8e-07 30.2 16.4 9.4e-05 22.1 0.4 3.5 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 PRP87231.1 - 1.9e-05 25.3 2.5 1.9e-05 25.3 2.5 5.3 3 2 3 6 6 6 2 Torus domain DUF3377 PF11857.8 PRP87231.1 - 0.26 11.2 0.5 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) zf-CCCH_2 PF14608.6 PRP87231.1 - 1.4 9.5 15.3 0.16 12.4 0.5 2.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger DUF89 PF01937.19 PRP87233.1 - 3.1e-101 338.8 0.8 3.8e-101 338.6 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 PPR_2 PF13041.6 PRP87235.1 - 4.7e-05 23.5 1.3 0.17 12.1 0.0 3.5 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 PRP87235.1 - 0.003 17.7 0.7 0.9 9.9 0.1 3.5 4 0 0 4 4 4 1 PPR repeat Folliculin PF11704.8 PRP87235.1 - 0.017 15.0 0.5 0.048 13.5 0.5 1.7 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PPR_long PF17177.4 PRP87235.1 - 0.019 14.3 0.2 0.14 11.5 0.0 2.4 2 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP DUF948 PF06103.11 PRP87235.1 - 0.06 13.6 1.9 0.16 12.2 1.9 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2459 PF09601.10 PRP87235.1 - 0.16 11.7 0.4 0.42 10.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) DUF883 PF05957.13 PRP87236.1 - 0.019 15.5 0.0 0.032 14.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Response_reg PF00072.24 PRP87240.1 - 3.1e-14 53.1 1.7 1.5e-13 50.9 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain DAHP_synth_1 PF00793.20 PRP87242.1 - 5.9e-100 333.7 0.0 7.3e-100 333.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Ehrlichia_rpt PF09528.10 PRP87242.1 - 0.13 11.7 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Pkinase_Tyr PF07714.17 PRP87245.1 - 8.8e-19 67.8 0.0 1.7e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87245.1 - 5.1e-16 58.8 0.0 9.6e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP87245.1 - 0.0028 18.2 1.4 0.0028 18.2 1.4 2.5 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif TIG_plexin PF17960.1 PRP87245.1 - 0.12 12.4 0.7 1.4 8.9 0.1 2.9 2 1 0 2 2 2 0 TIG domain Pkinase_Tyr PF07714.17 PRP87246.1 - 1.6e-20 73.5 0.7 7.3e-20 71.3 0.1 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87246.1 - 6.9e-18 65.0 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP87246.1 - 2.4e-06 28.0 1.2 5.9e-06 26.7 1.2 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif TIG_plexin PF17960.1 PRP87246.1 - 0.016 15.2 0.4 0.46 10.5 0.1 2.9 2 0 0 2 2 2 0 TIG domain DASH_Dam1 PF08653.10 PRP87246.1 - 0.1 12.4 0.1 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 Stevor PF17410.2 PRP87246.1 - 0.34 10.4 0.0 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame PH PF00169.29 PRP87247.1 - 2.1e-18 66.7 0.6 2.8e-11 43.8 0.4 2.7 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 PRP87247.1 - 2.1e-09 37.7 0.4 0.0026 18.2 1.0 2.9 2 1 0 2 2 2 2 Pleckstrin homology domain MMM1 PF10296.9 PRP87247.1 - 9.1e-07 28.2 0.0 3.7e-06 26.2 0.0 1.7 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 EXOSC1 PF10447.9 PRP87248.1 - 2.4e-16 60.3 1.0 4.2e-11 43.4 0.0 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 PRP87248.1 - 6.5e-11 41.8 0.1 1.5e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pro_isomerase PF00160.21 PRP87249.1 - 2.3e-46 158.0 0.0 2.5e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LpqV PF17301.2 PRP87249.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative lipoprotein LpqV DUF2427 PF10348.9 PRP87250.1 - 0.022 14.5 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Comm PF15957.5 PRP87250.1 - 0.041 14.2 0.9 0.095 13.1 0.0 1.9 1 1 1 2 2 2 0 Commissureless DUF3040 PF11239.8 PRP87250.1 - 0.099 12.9 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Sensor_TM1 PF13755.6 PRP87250.1 - 0.99 9.2 3.1 1.8 8.3 3.1 1.4 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain WD40 PF00400.32 PRP87251.1 - 9e-09 35.8 4.2 0.0057 17.5 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Got1 PF04178.12 PRP87253.1 - 1.3e-24 86.8 18.2 1.6e-22 80.0 18.1 2.4 1 1 0 1 1 1 1 Got1/Sft2-like family MCU PF04678.13 PRP87253.1 - 0.15 12.2 0.4 0.21 11.7 0.4 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Peptidase_S8 PF00082.22 PRP87254.1 - 3.8e-36 124.9 3.9 7.2e-36 124.0 3.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 PRP87254.1 - 0.013 16.2 0.0 0.027 15.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase inhibitor I9 Colipase-like PF15083.6 PRP87255.1 - 2.9 8.1 11.8 2.4 8.4 1.2 2.2 2 0 0 2 2 2 0 Colipase-like LBP_BPI_CETP PF01273.25 PRP87256.1 - 0.033 13.8 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 LBP / BPI / CETP family, N-terminal domain GFO_IDH_MocA PF01408.22 PRP87257.1 - 2.4e-22 80.0 0.0 4.1e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PRP87257.1 - 1.5e-09 37.9 0.0 3.7e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 PRP87257.1 - 0.0016 19.1 0.0 0.0028 18.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 PRP87257.1 - 0.085 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Alpha-amylase_C PF02806.18 PRP87258.1 - 8e-23 80.7 0.0 3.3e-22 78.8 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 PRP87258.1 - 9e-13 48.5 6.5 2.1e-12 47.3 0.2 2.6 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 PRP87258.1 - 2.2e-08 34.3 0.0 6.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AMPK1_CBM PF16561.5 PRP87258.1 - 0.061 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Glyco_hydro_79n PF03662.14 PRP87261.1 - 0.00066 18.7 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain LAG1-DNAbind PF09271.11 PRP87262.1 - 0.00089 19.9 0.0 0.0016 19.1 0.0 1.7 2 0 0 2 2 2 1 LAG1, DNA binding APH PF01636.23 PRP87263.1 - 2.7e-10 40.6 0.1 8.4e-10 39.0 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PRP87263.1 - 0.0017 17.7 0.8 0.0064 15.8 0.8 1.9 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 PRP87263.1 - 0.018 14.6 2.8 2.8 7.4 2.8 2.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 PRP87263.1 - 0.09 12.4 0.1 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 PRP87263.1 - 0.11 11.7 0.0 0.52 9.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like TraF PF13728.6 PRP87263.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 F plasmid transfer operon protein RNA_pol_A_CTD PF03118.15 PRP87264.1 - 0.07 12.9 0.2 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Tn916-Xis PF09035.10 PRP87264.1 - 0.12 12.6 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 Excisionase from transposon Tn916 G-patch PF01585.23 PRP87265.1 - 2.1e-15 56.3 4.6 3.8e-15 55.5 3.4 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 PRP87265.1 - 6.4e-06 26.2 2.7 6.4e-06 26.2 2.7 3.1 2 1 0 2 2 1 1 G-patch domain DUF913 PF06025.12 PRP87265.1 - 0.052 12.5 5.5 0.062 12.3 5.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 PRP87265.1 - 0.12 12.2 19.0 0.15 11.9 19.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 PRP87265.1 - 0.13 12.6 20.8 0.19 12.1 20.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF908 PF06012.12 PRP87265.1 - 0.58 9.5 7.8 0.62 9.4 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4746 PF15928.5 PRP87265.1 - 0.78 9.1 16.7 1.1 8.6 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CobT PF06213.12 PRP87265.1 - 1.7 7.9 15.9 2.6 7.4 15.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FGF-BP1 PF06473.12 PRP87265.1 - 2 8.2 18.7 9.2 6.0 16.3 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) DTHCT PF08070.11 PRP87265.1 - 2.1 9.1 32.9 30 5.4 32.0 2.4 1 1 0 1 1 1 0 DTHCT (NUC029) region Neur_chan_memb PF02932.16 PRP87265.1 - 2.9 7.9 6.2 3.1 7.8 6.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 PRP87265.1 - 4.5 6.0 16.7 6.4 5.5 16.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FRG2 PF15315.6 PRP87265.1 - 5.9 7.1 17.9 12 6.0 17.9 1.5 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 SID-1_RNA_chan PF13965.6 PRP87265.1 - 6.5 5.0 4.5 6.2 5.1 4.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 PRP87265.1 - 6.8 4.8 22.1 9.3 4.4 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RasGAP PF00616.19 PRP87266.1 - 1.1e-08 35.1 0.1 1.2e-05 25.2 0.1 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase PSI PF01437.25 PRP87266.1 - 1.7e-07 31.6 40.2 0.0025 18.3 10.9 3.9 3 0 0 3 3 3 3 Plexin repeat Insulin_TMD PF17870.1 PRP87266.1 - 0.019 15.0 1.1 0.019 15.0 1.1 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PSI_integrin PF17205.3 PRP87266.1 - 0.035 13.8 36.6 0.011 15.4 8.9 3.7 3 0 0 3 3 3 0 Integrin plexin domain TIG PF01833.24 PRP87266.1 - 0.041 13.9 24.1 0.067 13.3 3.3 5.5 5 1 0 5 5 5 0 IPT/TIG domain Cytomega_TRL10 PF06084.11 PRP87266.1 - 0.057 13.4 1.4 0.16 12.0 1.4 1.7 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Mid2 PF04478.12 PRP87266.1 - 1.6 8.6 5.1 0.18 11.6 0.3 1.9 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Not3 PF04065.15 PRP87267.1 - 3.3e-84 282.0 21.6 5.7e-84 281.2 21.6 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 PRP87267.1 - 8.5e-43 145.6 10.6 3e-42 143.8 10.6 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family COG5 PF10392.9 PRP87267.1 - 0.0069 16.6 11.0 0.16 12.1 0.5 3.5 2 1 2 4 4 4 2 Golgi transport complex subunit 5 Cep57_MT_bd PF06657.13 PRP87267.1 - 0.027 14.9 0.5 0.027 14.9 0.5 2.9 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2203 PF09969.9 PRP87267.1 - 0.21 12.3 10.6 3 8.6 2.5 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) V-SNARE PF05008.15 PRP87267.1 - 1.2 9.5 13.8 0.12 12.8 0.7 3.1 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus ABC_tran_CTD PF16326.5 PRP87267.1 - 2.8 8.3 11.5 0.82 10.0 0.4 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain Syntaxin_2 PF14523.6 PRP87267.1 - 4.9 7.6 11.6 0.26 11.7 1.9 3.0 2 1 0 2 2 2 0 Syntaxin-like protein DUF4363 PF14276.6 PRP87267.1 - 6.2 7.0 13.2 2.5 8.3 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Exonuc_VII_S PF02609.16 PRP87267.1 - 9.8 6.3 8.0 2.2 8.4 0.4 3.2 2 1 1 3 3 3 0 Exonuclease VII small subunit Spot_14 PF07084.12 PRP87268.1 - 0.061 13.5 0.9 0.44 10.7 0.1 2.4 2 1 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 SOGA PF11365.8 PRP87268.1 - 0.4 11.8 4.0 0.94 10.6 0.6 2.6 3 0 0 3 3 3 0 Protein SOGA LIM PF00412.22 PRP87269.1 - 1.1e-16 60.8 18.8 1.9e-08 34.4 3.7 3.2 2 1 0 2 2 2 2 LIM domain Paz_1 PF18349.1 PRP87273.1 - 0.047 13.7 0.2 6.8 6.7 0.0 2.5 2 0 0 2 2 2 0 PAZ domain MCM_N PF14551.6 PRP87273.1 - 0.53 10.9 5.7 0.68 10.5 1.7 2.7 3 0 0 3 3 3 0 MCM N-terminal domain SbcD_C PF12320.8 PRP87273.1 - 2.5 8.4 7.8 39 4.6 0.0 3.7 3 1 0 3 3 3 0 Type 5 capsule protein repressor C-terminal domain CPG4 PF15481.6 PRP87274.1 - 0.0046 17.6 5.5 0.96 10.1 0.2 2.2 1 1 1 2 2 2 2 Chondroitin proteoglycan 4 SH3_1 PF00018.28 PRP87276.1 - 1.1e-24 85.8 1.0 4.3e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 PRP87276.1 - 1e-20 73.2 0.0 1e-11 44.3 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 PRP87276.1 - 2.4e-20 72.1 0.4 4.2e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain ANAPC5 PF12862.7 PRP87276.1 - 0.019 15.0 0.1 0.033 14.2 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF1955 PF09205.10 PRP87277.1 - 0.069 12.9 0.7 0.073 12.8 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Pkinase_Tyr PF07714.17 PRP87278.1 - 0.00018 20.9 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87278.1 - 0.00031 20.2 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF1420 PF07220.11 PRP87278.1 - 0.047 12.3 0.0 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1420) BCNT PF07572.12 PRP87278.1 - 0.12 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Bucentaur or craniofacial development COMM_domain PF07258.14 PRP87279.1 - 8.2e-15 54.7 0.6 8.2e-15 54.7 0.6 2.1 3 0 0 3 3 3 1 COMM domain COMMD1_N PF17221.3 PRP87279.1 - 0.043 14.1 0.1 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 COMMD1 N-terminal domain MRJP PF03022.16 PRP87280.1 - 2.1e-25 89.6 0.0 2.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 PRP87280.1 - 0.0018 18.2 0.0 4.4 7.5 0.0 3.0 2 0 0 2 2 2 2 NHL repeat Reg_prop PF07494.11 PRP87280.1 - 0.026 14.7 0.2 20 5.8 0.0 3.4 3 0 0 3 3 3 0 Two component regulator propeller SGL PF08450.12 PRP87280.1 - 0.078 12.5 0.0 35 3.8 0.0 3.1 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region NAD_binding_1 PF00175.21 PRP87281.1 - 3.2e-27 95.3 0.0 5.2e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PRP87281.1 - 1.3e-22 80.0 0.0 2.4e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 PRP87281.1 - 9.7e-07 29.0 0.0 3.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SCAMP PF04144.13 PRP87283.1 - 7.2e-26 91.5 18.8 9.3e-26 91.2 18.8 1.1 1 0 0 1 1 1 1 SCAMP family DUF3377 PF11857.8 PRP87283.1 - 0.056 13.4 0.2 0.056 13.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF2070 PF09843.9 PRP87283.1 - 2 6.6 13.7 2.5 6.3 13.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) GpcrRhopsn4 PF10192.9 PRP87284.1 - 2.4e-38 132.0 21.7 3.6e-38 131.5 21.7 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain CC2D2AN-C2 PF15625.6 PRP87284.1 - 4.2e-21 75.5 0.1 4.2e-21 75.5 0.1 2.0 2 0 0 2 2 2 1 CC2D2A N-terminal C2 domain DUF5523 PF17661.1 PRP87284.1 - 1.8e-08 34.4 18.9 1.8e-08 34.4 18.9 4.0 3 1 0 3 3 3 1 Family of unknown function (DUF5523) C2 PF00168.30 PRP87284.1 - 6.2e-07 29.6 0.2 2.2e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 C2 domain Lung_7-TM_R PF06814.13 PRP87284.1 - 0.0028 16.9 17.6 0.0028 16.9 17.6 1.6 2 0 0 2 2 2 1 Lung seven transmembrane receptor V-SNARE PF05008.15 PRP87284.1 - 0.32 11.4 7.2 0.28 11.6 1.5 3.2 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Sel1 PF08238.12 PRP87285.1 - 1.8e-65 215.9 40.8 7.5e-08 32.8 0.1 11.4 11 0 0 11 11 11 9 Sel1 repeat TPR_7 PF13176.6 PRP87285.1 - 6e-05 22.8 16.0 0.14 12.2 0.2 7.3 5 2 2 7 7 7 2 Tetratricopeptide repeat PNPase PF03726.14 PRP87285.1 - 0.052 14.0 0.5 0.15 12.5 0.5 1.8 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain TPR_2 PF07719.17 PRP87285.1 - 0.074 13.2 37.0 0.31 11.3 1.1 9.3 9 1 0 9 9 8 0 Tetratricopeptide repeat DNA_pol3_gamma3 PF12169.8 PRP87285.1 - 0.083 12.8 0.8 0.67 9.9 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III TPR_16 PF13432.6 PRP87285.1 - 0.32 11.7 23.7 0.83 10.4 0.4 6.6 4 2 3 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 PRP87285.1 - 0.32 11.5 20.6 6.9 7.3 0.8 7.9 8 3 2 10 10 10 0 Tetratricopeptide repeat DUF5344 PF17279.2 PRP87285.1 - 1.4 9.5 11.8 4.7 7.9 0.8 4.7 3 1 1 4 4 4 0 Family of unknown function (DUF5344) TPR_12 PF13424.6 PRP87285.1 - 2.8 8.3 30.5 5.7 7.3 0.7 8.1 3 2 5 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 PRP87285.1 - 3.4 8.5 17.5 30 5.5 0.3 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 PRP87285.1 - 6.2 7.0 29.7 5.4 7.2 0.5 8.2 10 0 0 10 10 9 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 PRP87285.1 - 8.4 6.4 46.8 0.92 9.4 1.4 11.1 13 2 0 13 13 13 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 PRP87287.1 - 0.16 12.2 0.0 2.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family RCC1 PF00415.18 PRP87288.1 - 3.1e-60 200.6 7.2 5.8e-16 58.8 0.2 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP87288.1 - 6.2e-45 150.2 24.9 3.5e-10 39.4 0.4 6.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat HA PF03457.14 PRP87288.1 - 4.3e-15 55.8 4.6 0.00016 21.9 0.2 3.8 3 0 0 3 3 3 3 Helicase associated domain SUKH-3 PF14433.6 PRP87288.1 - 0.067 13.6 0.7 91 3.5 0.0 4.0 3 0 0 3 3 3 0 SUKH-3 immunity protein Epimerase PF01370.21 PRP87290.1 - 1.3e-20 73.9 0.0 1.7e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PRP87290.1 - 6.6e-12 45.0 0.0 8.7e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PRP87290.1 - 2e-11 43.5 0.0 2.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 PRP87290.1 - 1.1e-09 38.5 0.0 2.1e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PRP87290.1 - 9.4e-08 31.9 0.0 0.00026 20.6 0.1 2.8 2 1 0 2 2 2 2 NmrA-like family GDP_Man_Dehyd PF16363.5 PRP87290.1 - 9.7e-08 31.8 0.0 1.8e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PRP87290.1 - 0.00041 19.6 0.0 0.0006 19.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 PRP87290.1 - 0.005 16.3 0.0 0.0095 15.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP87290.1 - 0.0094 15.9 0.1 0.036 14.0 0.1 1.8 1 1 0 1 1 1 1 KR domain UL45 PF05473.12 PRP87292.1 - 0.0015 18.2 4.7 0.58 9.8 0.2 3.2 3 0 0 3 3 3 2 UL45 protein, carbohydrate-binding C-type lectin-like Homeodomain PF00046.29 PRP87292.1 - 0.0021 17.9 0.2 0.0042 16.9 0.2 1.5 1 0 0 1 1 1 1 Homeodomain Excalibur PF05901.11 PRP87292.1 - 0.018 15.6 2.1 51 4.6 0.0 3.5 3 0 0 3 3 3 0 Excalibur calcium-binding domain Binary_toxB PF03495.14 PRP87292.1 - 0.14 12.4 3.4 22 5.3 0.1 3.4 3 0 0 3 3 3 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DUF2433 PF10360.9 PRP87292.1 - 0.17 12.0 0.2 35 4.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2433) TSP_3 PF02412.18 PRP87292.1 - 5 6.9 17.3 15 5.4 1.1 3.6 3 0 0 3 3 3 0 Thrombospondin type 3 repeat Porin_3 PF01459.22 PRP87293.1 - 3.6e-29 102.1 2.3 5.5e-29 101.5 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic porin Ank_4 PF13637.6 PRP87293.1 - 4.1e-10 40.0 0.0 5.5e-05 23.6 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP87293.1 - 4.7e-06 26.8 0.0 0.00032 20.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP87293.1 - 6.9e-06 26.6 0.0 0.00021 21.8 0.0 2.3 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 PRP87293.1 - 0.0011 19.3 0.0 1.5 9.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 PRP87293.1 - 0.07 13.7 0.0 1.2 9.9 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Frag1 PF10277.9 PRP87294.1 - 1.4e-23 83.6 12.1 1.2e-22 80.6 12.1 1.9 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family GDPD PF03009.17 PRP87295.1 - 4.6e-58 197.0 0.0 1.4e-57 195.4 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 PRP87295.1 - 8.2e-36 122.5 8.0 1.3e-13 51.3 0.2 4.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87295.1 - 9.9e-24 83.4 3.3 1.1e-06 29.1 0.0 6.1 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP87295.1 - 3.9e-21 74.8 2.5 1e-05 25.7 0.1 5.6 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87295.1 - 5.6e-18 63.2 2.6 0.028 14.9 0.0 7.2 7 0 0 7 7 6 4 Ankyrin repeat Ank PF00023.30 PRP87295.1 - 2.4e-16 59.3 6.7 0.0043 17.5 0.0 7.2 7 0 0 7 7 6 5 Ankyrin repeat SPX PF03105.19 PRP87295.1 - 2.1e-13 51.0 5.8 7.5e-09 36.0 1.9 4.8 2 2 2 4 4 3 2 SPX domain CBM_20 PF00686.19 PRP87295.1 - 7.2e-13 48.3 1.6 3.2e-12 46.2 0.0 2.8 2 0 0 2 2 2 1 Starch binding domain Podoplanin PF05808.11 PRP87295.1 - 0.00019 21.6 0.3 0.00019 21.6 0.3 4.5 2 1 2 4 4 1 1 Podoplanin Insulin_TMD PF17870.1 PRP87295.1 - 0.033 14.2 1.7 0.09 12.9 1.7 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 PRP87295.1 - 0.11 12.4 0.5 0.24 11.4 0.5 1.5 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 PRP87295.1 - 0.12 12.1 3.8 0.27 11.0 3.8 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Arylesterase PF01731.20 PRP87297.1 - 0.029 14.5 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 Arylesterase MIP PF00230.20 PRP87298.1 - 6.9e-62 209.1 16.0 1.2e-61 208.4 16.0 1.3 1 0 0 1 1 1 1 Major intrinsic protein DNA_ligase_A_M PF01068.21 PRP87298.1 - 1.4e-48 165.2 0.0 4.7e-48 163.5 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PRP87298.1 - 3.5e-26 92.6 1.3 2.6e-25 89.7 1.3 2.3 1 1 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 PRP87298.1 - 6.6e-17 61.9 0.0 2.8e-16 59.9 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region LIG3_BRCT PF16759.5 PRP87298.1 - 6.7e-15 55.2 1.3 2.3e-10 40.6 0.1 3.1 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 PRP87298.1 - 3.1e-11 43.5 1.6 4e-05 23.9 0.2 3.5 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PRP87298.1 - 3.9e-09 36.8 1.5 3.2e-05 24.3 0.0 3.3 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 PRP87298.1 - 2.8e-05 24.5 0.0 0.00014 22.3 0.0 2.2 1 1 0 1 1 1 1 RNA ligase PTCB-BRCT PF12738.7 PRP87298.1 - 4.9e-05 23.2 1.2 0.00022 21.1 0.2 2.8 4 0 0 4 4 3 1 twin BRCT domain MMU163 PF17119.5 PRP87298.1 - 0.038 13.1 3.4 0.094 11.9 3.4 1.6 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis AAA_11 PF13086.6 PRP87298.1 - 0.13 12.1 6.6 0.44 10.3 3.5 2.5 2 0 0 2 2 2 0 AAA domain MtrF PF09472.10 PRP87298.1 - 0.14 11.6 0.1 0.36 10.2 0.1 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) RNA_pol_Rpc4 PF05132.14 PRP87298.1 - 2.3 8.7 14.0 2.8 8.4 7.1 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 RPA43_OB PF17875.1 PRP87298.1 - 5.9 7.5 10.9 5.7 7.6 3.0 2.8 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Homeodomain PF00046.29 PRP87299.1 - 9.8e-06 25.3 0.7 1.8e-05 24.5 0.7 1.5 1 0 0 1 1 1 1 Homeodomain ELYS PF13934.6 PRP87300.1 - 2.4e-05 24.4 0.8 6e-05 23.1 0.6 1.7 1 1 0 1 1 1 1 Nuclear pore complex assembly DUF4298 PF14131.6 PRP87300.1 - 0.073 13.0 0.2 0.22 11.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) PfkB PF00294.24 PRP87301.1 - 7.6e-31 107.5 0.0 1.9e-14 53.7 0.0 2.3 2 1 0 2 2 2 2 pfkB family carbohydrate kinase LppC PF04348.13 PRP87301.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein Histone PF00125.24 PRP87303.1 - 1.7e-06 28.5 0.0 0.0055 17.1 0.0 2.5 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 Ank_4 PF13637.6 PRP87303.1 - 6.2e-05 23.5 0.0 0.00014 22.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP87303.1 - 0.0052 16.7 1.1 0.014 15.3 1.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP87303.1 - 0.0052 16.6 0.4 0.013 15.4 0.4 1.6 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.7 PRP87303.1 - 0.031 14.9 0.0 0.096 13.3 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP87303.1 - 0.11 12.8 0.1 4.3 7.8 0.1 3.4 3 1 0 3 3 3 0 Ankyrin repeats (many copies) WD40 PF00400.32 PRP87304.1 - 0.0098 16.7 13.3 1.4 9.9 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Lung_7-TM_R PF06814.13 PRP87305.1 - 3.4e-42 144.7 23.2 5.8e-42 143.9 23.2 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 PRP87305.1 - 0.14 11.6 26.1 0.25 10.7 26.1 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain FUSC_2 PF13515.6 PRP87307.1 - 3.5e-18 65.9 8.4 3.5e-18 65.9 8.4 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 PRP87307.1 - 8.8e-17 60.9 6.8 1.1e-09 37.4 2.8 2.8 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.8 PRP87307.1 - 2.1e-12 46.7 1.2 2.1e-12 46.7 1.2 2.5 2 1 0 3 3 3 1 Aluminium activated malate transporter ArAE_2 PF10334.9 PRP87307.1 - 1.4e-08 34.9 6.2 5.7e-05 23.1 1.3 2.7 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 PRP87307.1 - 3e-07 29.9 0.8 3e-07 29.9 0.8 2.5 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal DUF3683 PF12447.8 PRP87307.1 - 0.074 13.2 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) FTP PF07504.13 PRP87307.1 - 0.19 11.6 1.1 0.26 11.1 0.1 1.8 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif DUF1056 PF06341.11 PRP87307.1 - 2.9 8.3 6.2 1.6 9.1 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) Peptidase_U4 PF03419.13 PRP87307.1 - 9.4 5.4 13.4 2.1 7.6 5.0 2.4 2 0 0 2 2 2 0 Sporulation factor SpoIIGA P2X_receptor PF00864.19 PRP87308.1 - 6e-13 48.6 0.6 2e-06 27.2 0.1 2.3 2 0 0 2 2 2 2 ATP P2X receptor Acyl-CoA_dh_1 PF00441.24 PRP87309.1 - 6.1e-42 143.4 0.1 9.5e-42 142.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PRP87309.1 - 3.7e-35 121.0 0.0 7.5e-35 120.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PRP87309.1 - 2.5e-27 94.9 0.1 4.5e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PRP87309.1 - 9.8e-14 51.8 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 PRP87309.1 - 0.0044 16.7 0.0 0.019 14.6 0.0 2.0 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short PF00106.25 PRP87310.1 - 1.4e-18 67.0 0.1 5e-17 62.0 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP87310.1 - 1.2e-13 51.2 0.0 5.5e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase LAG1-DNAbind PF09271.11 PRP87311.1 - 0.0057 17.3 0.0 0.01 16.5 0.0 1.6 1 1 0 1 1 1 1 LAG1, DNA binding PilW PF16074.5 PRP87311.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Type IV Pilus-assembly protein W Spore_III_AB PF09548.10 PRP87313.1 - 0.08 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) TylF PF05711.11 PRP87313.1 - 0.11 11.8 0.5 0.59 9.4 0.2 2.0 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) EMP24_GP25L PF01105.24 PRP87313.1 - 1.3 8.9 7.8 0.17 11.8 2.7 2.1 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MCLC PF05934.11 PRP87313.1 - 1.3 7.6 3.0 2 7.1 3.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) AAA_32 PF13654.6 PRP87314.1 - 1.3e-26 93.5 0.5 4.9e-15 55.3 0.0 3.7 3 1 1 4 4 4 3 AAA domain Lon_C PF05362.13 PRP87314.1 - 1.3e-08 34.7 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain VWA PF00092.28 PRP87315.1 - 4.5e-17 62.9 0.0 5.3e-16 59.4 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 PRP87315.1 - 8.9e-13 48.5 0.0 1.5e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 PRP87315.1 - 1e-11 45.4 0.2 8e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Vwaint PF14624.6 PRP87315.1 - 1.6e-05 25.0 0.6 3.5e-05 23.9 0.6 1.6 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_CoxE PF05762.14 PRP87315.1 - 0.00092 18.7 0.0 0.0048 16.3 0.0 2.1 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein CobT_C PF11775.8 PRP87315.1 - 0.062 12.9 0.1 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT VWA domain ChiW_Ig_like PF18683.1 PRP87315.1 - 0.098 12.9 1.7 0.41 10.9 0.2 2.2 2 0 0 2 2 2 0 Chitinase W immunoglobulin-like domain vWA-TerF-like PF10138.9 PRP87315.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus Ank_2 PF12796.7 PRP87316.1 - 2e-20 73.1 1.1 1.5e-08 35.1 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) GST_N PF02798.20 PRP87316.1 - 2.3e-15 56.7 0.0 6e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP87316.1 - 1.9e-14 53.6 0.0 4.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank_4 PF13637.6 PRP87316.1 - 6.6e-12 45.7 1.3 0.38 11.4 0.0 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) GST_N_3 PF13417.6 PRP87316.1 - 1.1e-11 45.0 0.0 2.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP87316.1 - 1.9e-09 37.7 0.0 3.8e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP87316.1 - 6.6e-09 35.7 0.1 1.6e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank PF00023.30 PRP87316.1 - 1.2e-06 28.6 6.3 4.9 7.8 0.1 6.6 5 2 2 7 7 7 1 Ankyrin repeat GST_C_3 PF14497.6 PRP87316.1 - 7.6e-06 26.0 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank_3 PF13606.6 PRP87316.1 - 4.8e-05 23.4 4.2 20 6.1 0.0 6.4 8 0 0 8 8 7 0 Ankyrin repeat Ank_5 PF13857.6 PRP87316.1 - 0.012 15.9 6.1 15 6.0 0.0 5.9 4 2 2 6 6 6 0 Ankyrin repeats (many copies) Aquarius_N PF16399.5 PRP87317.1 - 5.8e-241 801.9 0.0 9.1e-241 801.2 0.0 1.3 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 PRP87317.1 - 2.4e-29 102.9 10.3 8.6e-29 101.1 0.0 3.6 4 1 0 4 4 4 1 AAA domain AAA_12 PF13087.6 PRP87317.1 - 6.9e-27 94.4 0.0 2.4e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP87317.1 - 2.4e-08 34.4 0.4 2.6e-07 31.1 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 PRP87317.1 - 3.4e-07 30.2 0.0 0.0039 16.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 PRP87317.1 - 0.00022 21.3 0.5 0.00076 19.5 0.0 2.1 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 PRP87317.1 - 0.0008 19.0 0.4 0.0078 15.8 0.0 2.5 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 PRP87317.1 - 0.0065 16.3 0.3 0.014 15.2 0.3 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 PRP87317.1 - 0.0071 16.8 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP87317.1 - 0.015 15.7 0.0 0.082 13.3 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PRP87317.1 - 0.024 14.9 0.0 0.21 11.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 PRP87317.1 - 0.025 13.9 0.0 0.025 13.9 0.0 2.5 3 0 0 3 3 3 0 KaiC DUF2075 PF09848.9 PRP87317.1 - 0.026 13.8 0.2 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 PRP87317.1 - 0.04 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 PRP87317.1 - 0.082 12.3 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Spore_III_AF PF09581.10 PRP87317.1 - 0.56 10.2 3.2 1.1 9.3 3.2 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TCTP PF00838.17 PRP87318.1 - 3.8e-66 222.5 4.7 4.2e-66 222.4 4.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF2779 PF11074.8 PRP87318.1 - 0.0046 17.4 0.1 0.0058 17.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) Imm57 PF15596.6 PRP87318.1 - 0.018 15.4 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 57 PfUIS3 PF11567.8 PRP87318.1 - 0.037 14.4 0.1 0.063 13.6 0.1 1.4 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein Mus7 PF09462.10 PRP87318.1 - 0.1 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family SF3b10 PF07189.11 PRP87319.1 - 8.3e-37 125.2 0.0 9.5e-37 125.0 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF2264 PF10022.9 PRP87319.1 - 0.0013 17.9 0.1 0.0015 17.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) BAR PF03114.18 PRP87320.1 - 3.8e-28 98.8 13.6 4.2e-28 98.6 11.5 1.9 2 0 0 2 2 2 1 BAR domain adh_short PF00106.25 PRP87320.1 - 4.1e-28 98.2 0.1 2.9e-19 69.3 0.0 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP87320.1 - 8.5e-19 68.0 0.0 2.1e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SH3_9 PF14604.6 PRP87320.1 - 3.5e-16 58.8 0.2 7.3e-16 57.8 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP87320.1 - 7.3e-15 54.3 0.0 1.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP87320.1 - 2e-09 37.0 0.0 4.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain KR PF08659.10 PRP87320.1 - 6.1e-07 29.5 1.1 3e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 PRP87320.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein COG5 PF10392.9 PRP87320.1 - 0.00036 20.7 1.0 0.0023 18.1 0.2 2.3 1 1 1 2 2 2 1 Golgi transport complex subunit 5 Arfaptin PF06456.13 PRP87320.1 - 0.0078 15.8 10.5 0.15 11.6 10.5 2.2 1 1 0 1 1 1 1 Arfaptin-like domain Baculo_PEP_C PF04513.12 PRP87320.1 - 0.058 13.4 0.8 0.14 12.2 0.2 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec34 PF04136.15 PRP87320.1 - 0.33 10.8 4.8 0.55 10.1 1.2 2.5 1 1 1 2 2 2 0 Sec34-like family Cytochrom_B562 PF07361.11 PRP87320.1 - 2.9 8.6 10.3 0.73 10.5 3.6 2.8 1 1 1 2 2 2 0 Cytochrome b562 La PF05383.17 PRP87321.1 - 1.6e-18 66.5 0.2 3.2e-18 65.5 0.2 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 PRP87321.1 - 1.5e-05 24.7 0.1 5.8e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 PRP87322.1 - 1.6e-110 368.6 0.0 2.1e-62 210.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87322.1 - 1.6e-57 194.7 0.0 4.3e-37 127.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP87322.1 - 1.8e-08 34.1 0.0 0.0043 16.4 0.0 2.8 2 1 1 3 3 3 2 Kinase-like APH PF01636.23 PRP87322.1 - 2.7e-08 34.1 0.2 0.0029 17.6 0.0 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP87322.1 - 2.5e-07 29.8 0.2 4.6e-06 25.7 0.1 2.8 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP87322.1 - 6.3e-07 29.0 0.1 0.00034 20.0 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP87322.1 - 1.2e-06 28.3 0.3 9.3e-05 22.1 0.0 2.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PRP87322.1 - 4.3e-06 25.9 0.6 0.025 13.6 0.2 2.5 2 0 0 2 2 2 2 Haspin like kinase domain Seadorna_VP7 PF07387.11 PRP87322.1 - 0.00051 19.2 0.2 0.59 9.1 0.0 2.4 2 0 0 2 2 2 2 Seadornavirus VP7 YukC PF10140.9 PRP87322.1 - 0.002 17.1 0.1 0.11 11.4 0.1 2.4 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC DUF5582 PF17819.1 PRP87322.1 - 0.0046 17.4 1.6 0.009 16.5 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5582) Pox_ser-thr_kin PF05445.11 PRP87322.1 - 0.011 14.8 0.4 0.95 8.4 0.1 2.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase L_protein_N PF15518.6 PRP87322.1 - 0.033 14.0 0.0 6.1 6.8 0.0 2.5 2 0 0 2 2 2 0 L protein N-terminus FTA2 PF13095.6 PRP87322.1 - 0.044 13.4 0.1 1.4 8.5 0.0 3.0 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 PRP87322.1 - 0.057 12.9 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ank_4 PF13637.6 PRP87324.1 - 7.3e-25 87.0 0.2 6.5e-10 39.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP87324.1 - 2.2e-24 84.8 0.2 2.7e-09 37.0 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 PRP87324.1 - 3.3e-23 82.1 0.0 1.1e-10 41.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP87324.1 - 1.4e-20 73.1 0.1 7.3e-07 29.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87324.1 - 1.9e-19 67.7 0.0 2e-06 27.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Phosphonate-bd PF12974.7 PRP87324.1 - 0.063 12.9 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein 7tm_1 PF00001.21 PRP87325.1 - 0.00096 18.5 13.8 0.00096 18.5 13.8 1.8 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Borrelia_P83 PF05262.11 PRP87325.1 - 4.8 5.6 19.5 6.8 5.1 19.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Calc_CGRP_IAPP PF00214.19 PRP87325.1 - 9 6.7 11.6 6.7 7.1 4.9 3.0 3 0 0 3 3 3 0 Calcitonin / CGRP / IAPP family MFS_1 PF07690.16 PRP87326.1 - 7.5e-44 150.1 31.3 3.9e-43 147.7 25.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PRP87326.1 - 6.2e-13 48.1 15.5 4e-07 28.9 2.3 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 PRP87326.1 - 8.6e-09 34.8 9.8 8.6e-09 34.8 9.8 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 PRP87326.1 - 1.9e-07 30.8 6.6 1.9e-07 30.8 6.6 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 PRP87326.1 - 1.7e-06 27.1 7.6 1.7e-06 27.1 7.6 2.4 1 1 0 1 1 1 1 MFS_1 like family MFS_3 PF05977.13 PRP87326.1 - 1.4e-05 23.7 7.9 7.1e-05 21.4 1.2 2.3 2 1 0 2 2 2 2 Transmembrane secretion effector TRI12 PF06609.13 PRP87326.1 - 0.00037 19.0 3.7 0.0006 18.4 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Wzy_C PF04932.15 PRP87326.1 - 0.4 10.3 12.0 0.022 14.4 2.7 2.9 1 1 1 2 2 2 0 O-Antigen ligase Homeodomain PF00046.29 PRP87328.1 - 5.7e-16 58.1 4.9 3.6e-15 55.5 4.7 2.4 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP87328.1 - 0.0023 17.8 0.2 0.0064 16.4 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Pkinase PF00069.25 PRP87329.1 - 2.5e-67 227.0 0.0 3.7e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87329.1 - 1.1e-47 162.5 0.0 1.8e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 PRP87329.1 - 6.5e-09 35.8 0.2 1.8e-08 34.3 0.2 1.8 1 0 0 1 1 1 1 PX domain Pkinase_fungal PF17667.1 PRP87329.1 - 0.0039 16.0 0.3 0.019 13.8 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 PRP87329.1 - 0.039 13.5 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 PRP87329.1 - 0.045 13.7 0.0 0.19 11.6 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 PRP87329.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 FTCD_C PF04961.12 PRP87330.1 - 0.39 10.5 2.2 0.25 11.1 0.2 1.6 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Ribosomal_L4 PF00573.22 PRP87332.1 - 1.5e-54 184.6 0.0 2e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Med14 PF08638.11 PRP87333.1 - 2.8e-35 121.5 0.5 8.1e-24 84.1 0.0 2.5 2 0 0 2 2 2 2 Mediator complex subunit MED14 DUF2019 PF09450.10 PRP87333.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) DUF4980 PF16352.5 PRP87333.1 - 0.1 12.6 0.3 1.2 9.1 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4980) GAF PF01590.26 PRP87334.1 - 1.1e-06 29.3 0.0 1.6e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 PRP87334.1 - 1.1e-06 29.0 0.0 1.5e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PRP87334.1 - 0.0038 17.6 0.0 0.0076 16.6 0.0 1.5 1 1 0 1 1 1 1 GAF domain HMG_box_2 PF09011.10 PRP87334.1 - 0.14 12.8 0.4 0.22 12.1 0.4 1.3 1 0 0 1 1 1 0 HMG-box domain SOSSC PF15925.5 PRP87335.1 - 0.00054 21.2 3.5 0.00054 21.2 3.5 2.4 1 1 1 2 2 2 1 SOSS complex subunit C Acetyltransf_1 PF00583.25 PRP87336.1 - 5e-07 30.0 0.0 7.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP87336.1 - 3e-05 24.4 0.0 5.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP87336.1 - 0.001 19.0 0.0 0.0042 17.0 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP87336.1 - 0.0064 16.4 0.0 0.034 14.1 0.0 2.0 1 1 1 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.7 PRP87336.1 - 0.013 15.6 0.0 0.032 14.3 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5005 PF16396.5 PRP87336.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5005) Pkinase_Tyr PF07714.17 PRP87337.1 - 1.8e-25 89.7 0.1 1.7e-24 86.5 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87337.1 - 4.1e-19 69.0 0.0 3e-18 66.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain SEC-C PF02810.15 PRP87338.1 - 2.4e-08 33.7 3.8 4.9e-08 32.7 3.8 1.6 1 0 0 1 1 1 1 SEC-C motif CAP_C PF08603.11 PRP87338.1 - 3e-08 33.4 2.7 4.4e-08 32.9 2.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 PRP87338.1 - 0.025 14.3 0.4 0.045 13.5 0.4 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C Cg6151-P PF10233.9 PRP87341.1 - 0.068 13.5 13.9 0.13 12.6 13.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.13 PRP87341.1 - 0.21 11.1 1.3 0.88 9.1 1.3 2.0 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Lin-8 PF03353.15 PRP87341.1 - 2.6 7.5 8.0 3.6 7.0 8.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PKD_channel PF08016.12 PRP87342.1 - 1.5e-10 40.4 5.8 3.6e-10 39.1 5.8 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 PRP87342.1 - 0.0017 17.6 23.7 0.0046 16.2 23.6 1.7 1 1 0 1 1 1 1 Ion transport protein CTP_transf_1 PF01148.20 PRP87343.1 - 3.3 7.4 16.6 13 5.5 16.5 1.9 1 1 0 1 1 1 0 Cytidylyltransferase family DUF4336 PF14234.6 PRP87344.1 - 4.8e-10 39.1 0.0 7.8e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) TFIIIC_sub6 PF10419.9 PRP87345.1 - 2.3e-20 72.2 0.5 3.6e-20 71.6 0.1 1.5 2 0 0 2 2 2 1 TFIIIC subunit triple barrel domain Nro1 PF12753.7 PRP87345.1 - 0.077 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Helicase_C_2 PF13307.6 PRP87346.1 - 3e-51 174.0 0.0 1.7e-50 171.6 0.0 2.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 PRP87346.1 - 1.2e-50 171.6 0.7 1.2e-50 171.6 0.7 2.6 2 1 0 2 2 1 1 DEAD_2 zf-C3HC4_3 PF13920.6 PRP87346.1 - 7.9e-10 38.5 10.9 7.9e-10 38.5 10.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP87346.1 - 6.6e-07 29.1 11.9 1.6e-06 27.8 11.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP87346.1 - 1e-05 25.2 9.3 2.7e-05 23.9 9.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP87346.1 - 1.2e-05 25.1 9.9 3.3e-05 23.7 9.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 PRP87346.1 - 2.4e-05 24.4 0.0 2.4e-05 24.4 0.0 5.5 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 PRP87346.1 - 2.5e-05 24.5 10.4 7.5e-05 23.0 10.4 1.9 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.29 PRP87346.1 - 0.0001 22.1 0.0 0.0037 17.0 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 PRP87346.1 - 0.00042 20.1 11.1 0.0016 18.3 11.1 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP87346.1 - 0.081 13.0 5.8 0.11 12.6 4.2 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 PRP87346.1 - 0.16 11.8 7.4 0.48 10.2 7.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 PRP87346.1 - 0.23 11.6 4.5 0.67 10.1 4.5 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_14 PF17978.1 PRP87346.1 - 4.3 7.8 6.3 9.9 6.7 4.9 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PRP87346.1 - 7.5 6.9 10.2 2.8 8.3 6.6 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Sec7 PF01369.20 PRP87347.1 - 1.5e-42 145.4 0.3 3.2e-42 144.3 0.3 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PRP87347.1 - 3.5e-22 79.0 0.9 3.5e-22 79.0 0.9 4.8 6 1 0 7 7 7 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Zn_peptidase_2 PF04298.12 PRP87347.1 - 0.086 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DnaJ_C PF01556.18 PRP87348.1 - 3.1e-44 150.7 0.7 4.4e-44 150.2 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PRP87348.1 - 2.6e-28 97.9 2.4 4.1e-28 97.3 2.4 1.3 1 0 0 1 1 1 1 DnaJ domain GTP1_OBG PF01018.22 PRP87349.1 - 4.9e-42 143.1 9.1 6.6e-42 142.7 9.1 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 PRP87349.1 - 4.7e-21 75.0 0.0 7.1e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP87349.1 - 1.3e-09 37.7 0.0 3.3e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 PRP87349.1 - 4.3e-05 23.0 0.0 6.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1_C PF08438.10 PRP87349.1 - 0.055 14.0 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 GTPase of unknown function C-terminal GTP_EFTU PF00009.27 PRP87349.1 - 0.11 12.0 0.1 0.88 9.1 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain GP38 PF05268.11 PRP87349.1 - 3.6 7.2 12.6 0.94 9.1 4.0 2.1 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 cobW PF02492.19 PRP87350.1 - 1.2e-43 148.7 0.0 1.9e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PRP87350.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 PRP87350.1 - 0.017 15.0 0.1 0.061 13.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 PRP87350.1 - 0.041 13.6 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 PRP87350.1 - 0.055 13.2 0.1 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 PRP87350.1 - 0.092 12.3 1.3 0.68 9.4 1.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Viral_helicase1 PF01443.18 PRP87350.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 PRP87350.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 PRP87350.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-UBR PF02207.20 PRP87351.1 - 2.9e-18 65.8 10.3 2.9e-18 65.8 10.3 3.0 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PMP22_Claudin PF00822.20 PRP87351.1 - 0.19 11.6 2.0 0.58 10.0 0.7 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family LRR_6 PF13516.6 PRP87352.1 - 3.2e-11 42.4 7.6 0.00061 19.6 0.2 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 PRP87352.1 - 1.2e-05 25.5 2.3 0.13 12.7 0.1 3.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP87352.1 - 0.00012 22.1 0.1 8.5 7.4 0.0 5.0 4 0 0 4 4 4 1 Leucine Rich Repeat Na_trans_assoc PF06512.13 PRP87352.1 - 0.11 12.7 10.3 0.17 12.1 10.3 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated LRR_8 PF13855.6 PRP87352.1 - 0.38 10.5 7.2 6.5 6.6 2.0 3.7 2 1 0 2 2 2 0 Leucine rich repeat DUF4097 PF13349.6 PRP87353.1 - 8.9e-05 21.9 0.1 0.00019 20.9 0.1 1.5 1 1 0 1 1 1 1 Putative adhesin MFS_1 PF07690.16 PRP87354.1 - 2.2e-11 43.3 46.5 9.7e-07 28.0 25.8 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 PRP87354.1 - 5.4e-10 39.2 21.4 8.5e-10 38.6 14.8 3.7 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 TMEM52 PF14979.6 PRP87354.1 - 1.1 9.2 2.9 0.61 10.0 0.6 1.7 2 0 0 2 2 2 0 Transmembrane 52 G-alpha PF00503.20 PRP87355.1 - 5.7e-113 377.7 0.6 8.4e-113 377.1 0.6 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PRP87355.1 - 1.4e-12 47.4 0.4 6.1e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family 2OG-FeII_Oxy_3 PF13640.6 PRP87355.1 - 2.2e-11 44.5 0.3 5.5e-11 43.2 0.3 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PRP87355.1 - 0.0093 16.6 0.1 0.027 15.1 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Roc PF08477.13 PRP87355.1 - 0.088 13.0 0.6 18 5.5 0.1 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF4554 PF15091.6 PRP87356.1 - 0.27 10.1 2.5 0.44 9.4 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Ufm1 PF03671.14 PRP87357.1 - 8.9e-44 147.5 0.1 1.1e-43 147.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Rad60-SLD PF11976.8 PRP87357.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CDC45 PF02724.14 PRP87358.1 - 3.9e-127 425.2 11.5 1.3e-61 208.8 4.9 3.0 1 1 2 3 3 3 3 CDC45-like protein LSM PF01423.22 PRP87359.1 - 2.6e-09 36.7 0.0 3.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PRP87359.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain HpcH_HpaI PF03328.14 PRP87360.1 - 3.6e-37 127.6 0.8 1.7e-21 76.4 0.3 2.1 1 1 1 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 PRP87360.1 - 3.3e-17 62.7 0.1 2.6e-10 40.0 0.0 2.6 1 1 2 3 3 3 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF745 PF05335.13 PRP87361.1 - 0.005 16.6 2.5 0.005 16.6 2.5 7.1 2 2 6 9 9 9 1 Protein of unknown function (DUF745) DivIVA PF05103.13 PRP87361.1 - 0.012 15.7 10.3 0.012 15.7 10.3 8.4 3 1 2 8 8 8 0 DivIVA protein KxDL PF10241.9 PRP87361.1 - 0.022 15.0 0.2 0.022 15.0 0.2 8.9 3 2 4 9 9 9 0 Uncharacterized conserved protein DENN PF02141.21 PRP87362.1 - 2.5e-49 167.8 1.2 6.1e-49 166.5 1.2 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain WD40 PF00400.32 PRP87362.1 - 1.5e-47 158.6 35.4 1e-06 29.4 0.0 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat uDENN PF03456.18 PRP87362.1 - 8.8e-13 48.8 0.1 8.8e-13 48.8 0.1 2.3 3 0 0 3 3 3 1 uDENN domain SBF2 PF12335.8 PRP87362.1 - 3.5e-09 36.6 0.2 5.9e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 Myotubularin protein ANAPC4_WD40 PF12894.7 PRP87362.1 - 1.7e-08 34.6 1.4 0.4 11.0 0.1 5.2 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP87362.1 - 3.3e-07 29.4 7.3 2.1 6.9 0.7 5.4 2 2 3 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 PRP87362.1 - 1.8e-05 24.2 3.4 0.43 9.9 0.1 4.3 2 1 2 4 4 4 2 WD40-like domain dDENN PF03455.19 PRP87362.1 - 0.0002 21.3 3.0 0.0007 19.5 3.0 2.0 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 PRP87362.1 - 0.0058 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Pkinase_Tyr PF07714.17 PRP87363.1 - 1.5e-43 149.0 0.0 2.2e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87363.1 - 8.3e-33 113.9 0.0 1.3e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP87363.1 - 4.7e-11 43.0 6.6 1.1e-10 41.9 6.6 1.7 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif TIG PF01833.24 PRP87363.1 - 1.1e-08 35.0 52.6 4.1e-07 30.0 1.1 8.3 8 1 1 9 9 9 4 IPT/TIG domain Kinase-like PF14531.6 PRP87363.1 - 0.0046 16.3 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like GLEYA PF10528.9 PRP87363.1 - 0.052 14.0 0.0 0.19 12.2 0.0 2.0 1 0 0 1 1 1 0 GLEYA domain TMEM154 PF15102.6 PRP87363.1 - 0.067 13.1 0.0 0.067 13.1 0.0 2.3 3 0 0 3 3 3 0 TMEM154 protein family Kdo PF06293.14 PRP87363.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5305 PF17231.2 PRP87363.1 - 0.53 9.7 2.3 11 5.3 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5305) Response_reg PF00072.24 PRP87365.1 - 3.4e-25 88.4 0.0 1.4e-24 86.4 0.0 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 PRP87365.1 - 1.1e-24 87.1 0.2 2.8e-24 85.8 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP87365.1 - 1e-14 54.3 0.1 3.7e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP87365.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tox-PL-2 PF15643.6 PRP87366.1 - 0.15 12.2 1.6 0.13 12.3 0.8 1.4 1 1 0 1 1 1 0 Papain fold toxin 2 PH PF00169.29 PRP87367.1 - 1.8e-19 70.2 0.4 3.8e-19 69.1 0.4 1.6 1 0 0 1 1 1 1 PH domain PTEN_C2 PF10409.9 PRP87367.1 - 5.3e-18 65.1 0.0 3.5e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.6 PRP87367.1 - 2.8e-09 37.3 0.3 6.9e-09 36.1 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DSPc PF00782.20 PRP87367.1 - 7e-09 35.6 0.0 1.8e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP87367.1 - 6.5e-07 29.2 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PRP87367.1 - 9.4e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PH_8 PF15409.6 PRP87367.1 - 0.00015 22.0 0.5 0.0015 18.8 0.5 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PTPlike_phytase PF14566.6 PRP87367.1 - 0.00036 20.7 0.1 0.0015 18.7 0.0 2.1 3 0 0 3 3 3 1 Inositol hexakisphosphate PH_3 PF14593.6 PRP87367.1 - 0.0016 18.5 0.3 0.022 14.8 0.3 2.3 1 1 0 1 1 1 1 PH domain BCL_N PF04714.13 PRP87367.1 - 0.0041 17.1 1.6 0.43 10.7 0.4 2.5 2 0 0 2 2 2 1 BCL7, N-terminal conserver region PH_9 PF15410.6 PRP87367.1 - 0.096 13.1 0.1 0.31 11.4 0.1 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain Y_phosphatase2 PF03162.13 PRP87367.1 - 0.097 12.2 0.7 0.73 9.4 0.1 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.12 PRP87367.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SfsA PF03749.13 PRP87367.1 - 0.17 11.7 0.0 0.61 10.0 0.0 1.8 2 0 0 2 2 2 0 Sugar fermentation stimulation protein RE domain Peptidase_C48 PF02902.19 PRP87368.1 - 9.8e-38 130.2 1.0 9.8e-38 130.2 1.0 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain NAC PF01849.18 PRP87369.1 - 2.1e-24 85.3 0.1 3.1e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 NAC domain Tctex-1 PF03645.13 PRP87370.1 - 1.6e-07 31.5 0.1 1.9e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family Forkhead PF00250.18 PRP87370.1 - 0.075 13.3 0.1 0.088 13.1 0.1 1.2 1 0 0 1 1 1 0 Forkhead domain Ribosomal_L22 PF00237.19 PRP87371.1 - 2e-38 130.8 0.1 3.2e-38 130.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HTH_54 PF18607.1 PRP87372.1 - 0.0072 16.4 0.0 55 3.9 0.0 3.4 3 0 0 3 3 3 3 ParA helix turn helix domain EspB PF05802.11 PRP87372.1 - 0.033 14.2 0.0 6.4 6.7 0.0 3.1 2 1 0 2 2 2 0 Enterobacterial EspB protein DAPDH_C PF16654.5 PRP87372.1 - 0.19 11.5 0.0 48 3.8 0.0 3.5 3 0 0 3 3 3 0 Diaminopimelic acid dehydrogenase C-terminal domain RNA_lig_T4_1 PF09511.10 PRP87373.1 - 3.4e-16 59.8 0.2 3e-15 56.7 0.0 2.5 2 1 0 2 2 2 1 RNA ligase RNA_ligase PF09414.10 PRP87373.1 - 0.00026 21.4 0.2 0.0012 19.2 0.2 2.1 1 1 0 1 1 1 1 RNA ligase PIG-F PF06699.11 PRP87374.1 - 1.4e-32 113.3 6.3 1.7e-32 113.0 6.3 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F 7tm_7 PF08395.12 PRP87374.1 - 0.0027 17.0 3.8 0.19 10.9 2.2 2.1 2 0 0 2 2 2 2 7tm Chemosensory receptor DUF456 PF04306.13 PRP87374.1 - 0.0037 17.6 2.8 0.45 10.8 0.5 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF456) UPF0016 PF01169.19 PRP87374.1 - 0.13 12.6 2.2 0.51 10.7 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 DUF2530 PF10745.9 PRP87374.1 - 0.15 12.3 3.6 0.11 12.7 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Transgly_assoc PF04226.13 PRP87374.1 - 0.51 10.6 8.6 6.4 7.1 2.4 2.7 2 1 0 2 2 2 0 Transglycosylase associated protein Mito_carr PF00153.27 PRP87375.1 - 1.9e-06 27.7 0.4 1.9e-05 24.5 0.0 2.5 1 1 1 2 2 2 1 Mitochondrial carrier protein HTH_23 PF13384.6 PRP87375.1 - 0.14 12.0 0.4 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain FH2 PF02181.23 PRP87376.1 - 3.3e-84 283.2 14.1 7.9e-84 281.9 5.0 2.5 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 PRP87376.1 - 1.2e-30 106.6 5.2 1.2e-30 106.6 5.2 2.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP87376.1 - 1.3e-27 96.6 0.2 1.5e-26 93.1 0.0 2.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain DUF3361 PF11841.8 PRP87376.1 - 7.6e-06 25.9 0.8 0.069 13.1 0.1 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF3361) Hydrolase_3 PF08282.12 PRP87377.1 - 9e-49 166.5 0.0 1.8e-48 165.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PRP87377.1 - 1e-12 48.1 0.0 4e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PRP87377.1 - 2.1e-09 38.0 0.2 5.8e-08 33.3 0.2 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PRP87377.1 - 0.00037 20.6 0.0 0.0016 18.6 0.0 2.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase FYVE PF01363.21 PRP87377.1 - 0.00055 20.0 10.6 0.00055 20.0 10.6 3.2 2 1 0 2 2 2 1 FYVE zinc finger HAD PF12710.7 PRP87377.1 - 0.0024 18.3 0.0 0.054 13.9 0.0 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Zf_RING PF16744.5 PRP87377.1 - 7 6.8 21.7 2.3 8.4 7.9 3.1 3 0 0 3 3 3 0 KIAA1045 RING finger G-alpha PF00503.20 PRP87378.1 - 6.1e-101 338.1 7.6 1.6e-99 333.4 7.6 2.0 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 PRP87378.1 - 7.1e-10 38.6 0.3 4.8e-09 35.9 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family HA2 PF04408.23 PRP87379.1 - 9.4e-22 77.4 0.0 9.4e-22 77.4 0.0 3.5 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PRP87379.1 - 5.4e-15 55.5 0.0 1.5e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PRP87379.1 - 1.5e-12 47.8 0.0 3.7e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PRP87379.1 - 3.2e-06 27.0 0.0 7.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PRP87379.1 - 1.2e-05 25.7 0.1 4.3e-05 23.8 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PRP87379.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PRP87379.1 - 0.0026 17.1 1.6 0.0033 16.7 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 PRP87379.1 - 0.0036 17.6 0.1 0.0094 16.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PRP87379.1 - 0.0052 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 PRP87379.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 PRP87379.1 - 0.035 14.1 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 PRP87379.1 - 0.035 13.8 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PRP87379.1 - 0.053 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PRP87379.1 - 0.075 13.6 0.0 0.3 11.6 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 PRP87379.1 - 0.084 13.4 0.3 0.084 13.4 0.3 4.0 2 1 1 3 3 2 0 AAA domain AAA_14 PF13173.6 PRP87379.1 - 0.11 12.5 0.2 0.86 9.6 0.2 2.3 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 PRP87379.1 - 0.22 11.1 0.9 0.5 9.9 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Microtub_bd PF16796.5 PRP87379.1 - 0.72 9.8 4.1 0.18 11.8 0.1 2.1 2 0 0 2 2 1 0 Microtubule binding MAPEG PF01124.18 PRP87380.1 - 9.6e-23 80.5 0.4 1.4e-22 80.0 0.4 1.2 1 0 0 1 1 1 1 MAPEG family DUF5400 PF17379.2 PRP87380.1 - 0.06 13.8 0.6 0.12 12.8 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5400) Pkinase_Tyr PF07714.17 PRP87381.1 - 8.8e-73 244.8 0.0 1.4e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87381.1 - 1.1e-49 169.2 0.0 1.7e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cellulase PF00150.18 PRP87381.1 - 5.6e-33 114.6 9.8 1.4e-21 77.1 5.3 2.4 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) LRR_8 PF13855.6 PRP87381.1 - 1.6e-28 98.2 95.4 5.5e-06 26.1 8.2 14.1 7 4 4 13 13 13 9 Leucine rich repeat LRR_4 PF12799.7 PRP87381.1 - 1.1e-27 95.7 93.9 0.0015 18.9 1.7 16.3 6 4 13 20 20 20 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP87381.1 - 8.6e-07 28.7 57.7 2.9 8.8 0.0 18.4 17 3 1 18 18 18 2 Leucine Rich Repeat Amnionless PF14828.6 PRP87381.1 - 3.5e-05 22.8 0.5 5.3e-05 22.2 0.5 1.2 1 0 0 1 1 1 1 Amnionless Kinase-like PF14531.6 PRP87381.1 - 0.00034 20.0 0.0 0.00061 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CD34_antigen PF06365.12 PRP87381.1 - 0.0035 17.0 0.1 0.0096 15.5 0.2 1.6 2 0 0 2 2 2 1 CD34/Podocalyxin family Pkinase_fungal PF17667.1 PRP87381.1 - 0.02 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PRP87381.1 - 0.095 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PRP87381.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beta-APP PF03494.13 PRP87381.1 - 3.3 7.6 5.1 8.5 6.3 5.1 1.7 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DUF1754 PF08555.10 PRP87382.1 - 0.012 16.4 9.6 0.012 16.4 9.6 2.0 1 1 1 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Acetyltransf_1 PF00583.25 PRP87383.1 - 5.8e-18 65.2 0.1 8.1e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PRP87383.1 - 2.1e-14 53.6 0.1 1e-13 51.3 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP87383.1 - 3.7e-12 46.5 0.5 6.9e-12 45.6 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PRP87383.1 - 5e-11 42.4 0.0 9.1e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 PRP87383.1 - 5.8e-05 22.8 0.0 7.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 PRP87383.1 - 0.00013 21.5 0.1 0.00015 21.3 0.1 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 PRP87383.1 - 0.00015 21.9 0.3 0.00038 20.6 0.3 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PRP87383.1 - 0.00017 22.2 0.1 0.0012 19.6 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 PRP87383.1 - 0.014 15.1 0.1 0.021 14.5 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 PRP87383.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AAA_30 PF13604.6 PRP87383.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF5071 PF16804.5 PRP87383.1 - 0.2 11.9 0.1 0.33 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) Pkinase_Tyr PF07714.17 PRP87384.1 - 6e-66 222.4 0.0 3.2e-65 220.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87384.1 - 3e-43 148.1 0.0 1e-42 146.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Cellulase PF00150.18 PRP87384.1 - 1.5e-30 106.6 7.2 1.6e-22 80.3 1.4 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) LRR_8 PF13855.6 PRP87384.1 - 8e-30 102.4 82.5 1.9e-07 30.7 1.1 14.0 7 2 5 14 14 14 11 Leucine rich repeat LRR_4 PF12799.7 PRP87384.1 - 1.7e-27 95.0 88.6 0.00081 19.7 2.3 16.9 9 4 8 18 18 18 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP87384.1 - 6.2e-07 29.1 59.3 0.73 10.6 1.2 20.1 24 1 0 24 24 24 2 Leucine Rich Repeat DUF4434 PF14488.6 PRP87384.1 - 0.036 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) DUF3106 PF11304.8 PRP87385.1 - 0.053 14.0 0.3 0.13 12.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) HemY_N PF07219.13 PRP87386.1 - 0.054 13.7 1.9 2.2 8.5 0.0 3.3 3 0 0 3 3 3 0 HemY protein N-terminus zf-LITAF-like PF10601.9 PRP87386.1 - 4.7 7.5 5.8 1.8 8.9 0.0 3.2 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain P34-Arc PF04045.14 PRP87390.1 - 6e-86 288.0 0.1 1.3e-85 287.0 0.1 1.5 1 1 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 PRP87391.1 - 1.8e-77 258.6 7.8 2e-77 258.5 7.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Octopine_DH PF02317.17 PRP87391.1 - 0.047 13.8 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain GIDE PF12483.8 PRP87392.1 - 2e-09 37.0 0.0 5.1e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 E3 Ubiquitin ligase GP68 PF17469.2 PRP87392.1 - 0.032 14.6 0.0 0.16 12.4 0.0 2.0 2 0 0 2 2 2 0 Phage protein Gp68 Ras PF00071.22 PRP87394.1 - 2e-33 115.3 0.5 2.7e-33 114.9 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP87394.1 - 1.6e-13 51.0 0.1 2.9e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PRP87394.1 - 2e-05 24.5 0.1 0.015 15.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 PRP87394.1 - 2.8e-05 23.6 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP87394.1 - 0.0045 17.0 0.1 0.0081 16.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 PRP87394.1 - 0.023 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 PRP87394.1 - 0.074 12.5 0.5 0.11 12.0 0.1 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SNF2_N PF00176.23 PRP87395.1 - 1.8e-64 217.7 0.2 3.7e-64 216.7 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 PRP87395.1 - 8.9e-33 112.2 3.3 4.8e-18 65.0 0.1 3.0 2 0 0 2 2 2 2 Bromodomain Chromo PF00385.24 PRP87395.1 - 5e-22 77.6 12.7 1.3e-13 50.6 3.0 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 PRP87395.1 - 3.2e-18 66.1 0.0 7.9e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FYRN PF05964.14 PRP87395.1 - 1.9e-14 53.2 0.2 3.8e-14 52.3 0.2 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 PRP87395.1 - 4.5e-11 42.7 0.0 1.8e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus ResIII PF04851.15 PRP87395.1 - 3.5e-06 27.1 0.0 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PRP87395.1 - 0.0014 17.8 1.4 0.0068 15.6 0.0 2.7 3 1 0 3 3 2 1 Class II histone deacetylase complex subunits 2 and 3 SLIDE PF09111.10 PRP87395.1 - 0.04 13.9 4.7 1.9 8.5 0.0 4.3 4 0 0 4 4 4 0 SLIDE AAA_22 PF13401.6 PRP87395.1 - 0.16 12.3 0.0 0.75 10.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Gti1_Pac2 PF09729.9 PRP87395.1 - 5.5 7.0 9.7 0.53 10.4 1.8 2.7 2 0 0 2 2 2 0 Gti1/Pac2 family Hemerythrin PF01814.23 PRP87395.1 - 8.5 7.0 7.6 44 4.7 0.1 3.8 5 0 0 5 5 5 0 Hemerythrin HHE cation binding domain PAS PF00989.25 PRP87396.1 - 0.068 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Fucokinase PF07959.12 PRP87398.1 - 4.4e-86 289.4 0.0 6.3e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 PRP87398.1 - 0.00051 20.2 0.0 0.0016 18.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PRP87398.1 - 0.018 15.4 0.0 0.076 13.4 0.0 2.0 1 0 0 1 1 1 0 GHMP kinases C terminal Pkinase_Tyr PF07714.17 PRP87399.1 - 3.4e-66 223.2 0.0 4.8e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87399.1 - 1e-44 152.9 0.0 1.6e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Protocadherin PF08374.11 PRP87399.1 - 0.0035 17.3 0.7 0.0086 16.1 0.7 1.6 1 0 0 1 1 1 1 Protocadherin DUF5305 PF17231.2 PRP87399.1 - 0.26 10.7 3.3 0.26 10.7 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5305) SpoIIE PF07228.12 PRP87400.1 - 2.7e-09 37.2 0.0 6.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 PRP87400.1 - 9.9e-06 25.4 0.0 0.082 12.5 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PRP87400.1 - 0.0018 17.9 0.1 0.0057 16.3 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Zip PF02535.22 PRP87403.1 - 2.5e-50 171.6 10.8 2.5e-50 171.6 10.8 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter Pkinase_Tyr PF07714.17 PRP87403.1 - 7.2e-34 117.2 0.0 1.1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87403.1 - 1.2e-20 74.0 0.0 2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP87403.1 - 1.4e-14 53.6 40.2 6.9e-08 32.1 7.5 5.8 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 PRP87403.1 - 2.8e-12 46.6 48.9 3.7e-06 27.2 2.9 7.0 4 2 2 7 7 7 4 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP87403.1 - 1.1e-09 38.7 3.3 3.1e-09 37.2 3.3 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP87403.1 - 0.00013 22.1 40.2 0.24 12.1 0.4 9.9 8 2 0 8 8 8 4 Leucine Rich Repeat 7TM_GPCR_Srb PF02175.16 PRP87403.1 - 0.031 14.1 0.4 0.073 12.8 0.4 1.6 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb Orf78 PF06024.12 PRP87403.1 - 0.3 11.4 0.9 1.4 9.3 0.8 2.1 2 0 0 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 PRP87403.1 - 0.35 10.7 1.1 1.1 9.2 1.1 1.8 1 0 0 1 1 1 0 TMEM154 protein family 6PF2K PF01591.18 PRP87404.1 - 3e-67 226.2 0.2 5.2e-67 225.4 0.2 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 PRP87404.1 - 1.3e-18 67.4 0.0 2.9e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 PRP87404.1 - 1e-08 35.5 0.1 2.3e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PRP87404.1 - 0.0075 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 PRP87404.1 - 0.017 14.6 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zincin_1 PF06262.11 PRP87404.1 - 0.17 12.0 0.3 0.63 10.2 0.1 2.0 2 0 0 2 2 2 0 Zincin-like metallopeptidase Patatin PF01734.22 PRP87405.1 - 1.6e-10 41.5 5.4 2.7e-10 40.8 2.4 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase NitrOD1 PF18549.1 PRP87407.1 - 0.019 14.9 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 TIG PF01833.24 PRP87408.1 - 1.9e-08 34.3 0.1 6.4e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 IPT/TIG domain Mito_carr PF00153.27 PRP87409.1 - 2.4e-65 216.5 0.7 3.9e-23 81.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 PRP87409.1 - 0.039 13.2 0.0 1.7 7.7 0.0 2.2 1 1 1 2 2 2 0 Fuseless Dynactin_p62 PF05502.13 PRP87410.1 - 3.8e-32 111.7 12.5 5.1e-20 71.7 6.3 2.2 2 0 0 2 2 2 2 Dynactin p62 family RGS PF00615.19 PRP87411.1 - 6.2e-12 45.8 0.2 4.1e-08 33.5 0.0 4.0 5 0 0 5 5 5 2 Regulator of G protein signaling domain SBF2 PF12335.8 PRP87411.1 - 8.5e-08 32.1 1.2 8.5e-08 32.1 1.2 3.5 2 1 0 2 2 2 1 Myotubularin protein MATH PF00917.26 PRP87411.1 - 2.1e-07 31.1 0.0 6e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 MATH domain Gluconate_2-dh3 PF13618.6 PRP87411.1 - 0.29 11.4 0.0 0.29 11.4 0.0 3.9 4 2 1 5 5 5 0 Gluconate 2-dehydrogenase subunit 3 DUF2730 PF10805.8 PRP87411.1 - 0.39 10.8 0.1 0.39 10.8 0.1 4.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) GAGE PF05831.11 PRP87411.1 - 4.1 8.0 10.9 1.3 9.6 0.1 2.6 2 0 0 2 2 2 0 GAGE protein MscS_TM PF12794.7 PRP87411.1 - 9.6 4.9 6.4 17 4.1 6.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 TPR_2 PF07719.17 PRP87412.1 - 7.2e-30 100.7 20.2 0.00054 19.9 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_1 PF00515.28 PRP87412.1 - 8.9e-27 91.8 22.2 2.8e-07 30.1 0.3 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 PRP87412.1 - 1e-22 78.4 14.5 0.0085 16.2 0.0 8.8 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 PRP87412.1 - 7.1e-19 66.9 14.5 0.046 14.6 0.0 9.1 3 1 6 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 PRP87412.1 - 2.5e-17 63.2 12.4 0.00012 22.6 0.3 6.4 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 PRP87412.1 - 1.2e-13 51.1 26.8 8.5e-06 26.0 1.6 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 PRP87412.1 - 3.1e-09 37.2 12.8 0.021 15.3 0.5 5.8 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP87412.1 - 1.2e-08 34.4 12.0 0.0032 17.1 0.1 5.7 2 1 3 5 5 5 2 TPR repeat TPR_17 PF13431.6 PRP87412.1 - 4.2e-08 33.0 22.6 0.0015 18.8 0.1 8.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP87412.1 - 2.7e-07 30.7 11.9 0.0016 18.5 1.2 4.5 2 1 4 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP87412.1 - 6.8e-07 29.4 16.7 0.08 13.2 3.5 5.2 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 PRP87412.1 - 6.6e-06 26.4 15.8 6.8 7.5 0.0 8.7 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP87412.1 - 8.3e-06 25.5 19.0 0.23 11.6 0.1 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 PRP87412.1 - 0.00066 19.0 7.5 0.09 12.0 2.6 3.4 1 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 PRP87412.1 - 0.0072 15.3 0.9 0.035 13.0 0.3 2.3 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 PRP87412.1 - 0.015 15.1 18.4 3.2 7.8 1.5 7.4 7 1 1 8 8 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP87412.1 - 0.044 13.9 5.6 39 4.4 0.0 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 PRP87412.1 - 0.12 12.5 1.0 1.2 9.3 0.0 2.7 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 5 BTAD PF03704.17 PRP87412.1 - 0.27 11.6 6.7 1.8 9.0 0.5 3.7 4 1 0 4 4 3 0 Bacterial transcriptional activator domain F-box PF00646.33 PRP87413.1 - 0.00042 20.1 0.4 0.0011 18.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 PRP87413.1 - 0.011 16.3 0.3 8.8 7.0 0.0 5.1 5 2 0 5 5 5 0 Ankyrin repeats (many copies) F-box_4 PF15966.5 PRP87413.1 - 0.021 14.7 0.4 0.021 14.7 0.4 2.1 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 PRP87413.1 - 0.029 14.3 0.5 0.06 13.3 0.5 1.6 1 0 0 1 1 1 0 F-box-like Ank_3 PF13606.6 PRP87415.1 - 0.00062 20.0 0.1 21 6.1 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat F-box PF00646.33 PRP87415.1 - 0.0049 16.7 0.6 0.014 15.3 0.6 1.8 1 0 0 1 1 1 1 F-box domain Ank_4 PF13637.6 PRP87415.1 - 0.006 17.1 0.1 4.6 7.9 0.0 4.1 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP87415.1 - 0.041 14.5 0.1 20 5.8 0.0 3.4 2 2 1 3 3 2 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP87415.1 - 0.1 12.9 0.0 36 4.8 0.0 3.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) LRR_8 PF13855.6 PRP87416.1 - 8.2e-64 211.3 151.2 6.1e-09 35.5 1.0 18.8 8 3 19 27 27 27 24 Leucine rich repeat LRR_4 PF12799.7 PRP87416.1 - 5.4e-53 176.1 168.6 2.1e-05 24.8 0.2 22.3 13 4 10 26 26 26 20 Leucine Rich repeats (2 copies) NYD-SP28 PF14772.6 PRP87416.1 - 9.3e-15 54.5 14.5 9.3e-15 54.5 14.5 4.3 3 2 0 4 4 4 1 Sperm tail NYD-SP28_assoc PF14775.6 PRP87416.1 - 2.3e-06 27.6 1.3 2.3e-06 27.6 1.3 3.0 3 0 0 3 3 3 1 Sperm tail C-terminal domain LRR_1 PF00560.33 PRP87416.1 - 0.00098 19.4 115.6 1 10.2 0.1 28.9 31 6 2 33 33 33 4 Leucine Rich Repeat DUF5612 PF18462.1 PRP87416.1 - 0.025 14.4 0.7 78 3.0 0.0 5.8 6 1 1 7 7 7 0 Domain of unknown function (DUF5612) CPL PF08144.11 PRP87417.1 - 3.8e-19 69.4 0.3 2.4e-16 60.4 0.0 4.2 2 2 1 3 3 3 1 CPL (NUC119) domain PUF PF00806.19 PRP87417.1 - 4.2e-05 23.0 0.2 0.064 13.0 0.0 3.3 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat DUF4279 PF14106.6 PRP87417.1 - 0.24 11.6 1.7 0.36 11.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) PUF PF00806.19 PRP87418.1 - 2.2e-32 108.9 10.2 1.7e-07 30.5 0.1 8.2 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat CPL PF08144.11 PRP87418.1 - 3.2e-05 24.3 1.3 3.5 8.0 0.2 4.2 2 1 1 3 3 3 3 CPL (NUC119) domain MIT PF04212.18 PRP87418.1 - 0.18 11.9 0.4 1.2 9.3 0.0 2.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Il2rg PF15874.5 PRP87419.1 - 3.5e-09 36.8 0.1 5.8e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain Senescence_reg PF04520.13 PRP87420.1 - 0.0053 17.6 9.5 0.041 14.7 9.5 2.0 1 1 0 1 1 1 1 Senescence regulator Ran_BP1 PF00638.18 PRP87421.1 - 7.7e-17 61.7 2.7 2e-16 60.4 2.7 1.7 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 PRP87421.1 - 1.4e-09 38.5 11.4 1.4e-09 38.5 11.4 3.5 2 2 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Filament PF00038.21 PRP87422.1 - 1e-05 25.3 39.9 1e-05 25.3 39.9 5.7 1 1 4 5 5 5 2 Intermediate filament protein DUF1216 PF06746.11 PRP87422.1 - 0.016 15.2 2.9 0.016 15.2 2.9 5.9 5 3 1 6 6 6 0 Protein of unknown function (DUF1216) YodL PF14191.6 PRP87422.1 - 0.094 13.6 4.1 0.33 11.8 0.2 3.6 2 0 0 2 2 2 0 YodL-like DUF1824 PF08854.10 PRP87422.1 - 0.21 11.5 6.0 0.17 11.8 1.8 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) SNARE PF05739.19 PRP87422.1 - 1.5 8.9 4.5 8.7 6.4 0.4 3.4 2 0 0 2 2 2 0 SNARE domain DUF3800 PF12686.7 PRP87422.1 - 3.8 8.2 9.0 4.4e+03 -1.7 9.0 4.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) DUF5407 PF17401.2 PRP87422.1 - 6 7.2 11.0 0.29 11.4 2.0 3.6 3 1 0 3 3 3 0 Family of unknown function (DUF5407) HOOK PF05622.12 PRP87423.1 - 0.0082 14.4 13.8 0.0093 14.2 13.8 1.1 1 0 0 1 1 1 1 HOOK protein Tektin PF03148.14 PRP87423.1 - 0.01 14.6 14.5 0.019 13.7 14.5 1.5 1 1 0 1 1 1 0 Tektin family ADIP PF11559.8 PRP87423.1 - 0.011 15.8 8.7 0.011 15.8 8.7 2.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding KxDL PF10241.9 PRP87423.1 - 0.012 15.8 2.8 0.012 15.8 2.8 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.15 PRP87423.1 - 0.018 14.6 8.3 0.02 14.5 8.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 PRP87423.1 - 0.024 14.6 20.0 0.14 12.2 1.1 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding YlqD PF11068.8 PRP87423.1 - 0.12 12.7 9.7 0.24 11.8 9.7 1.7 1 1 0 1 1 1 0 YlqD protein YfcL PF08891.11 PRP87423.1 - 0.17 12.2 1.9 0.17 12.2 0.1 1.8 2 0 0 2 2 2 0 YfcL protein Fib_alpha PF08702.10 PRP87423.1 - 0.19 11.9 12.2 0.26 11.5 12.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 PRP87423.1 - 0.23 8.9 12.7 0.27 8.7 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 PRP87423.1 - 0.27 10.5 8.9 0.063 12.6 5.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FliD_C PF07195.12 PRP87423.1 - 0.62 9.4 9.9 0.11 11.8 3.7 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DHHA1 PF02272.19 PRP87423.1 - 0.99 9.8 6.4 3.6 8.0 1.9 2.1 2 0 0 2 2 2 0 DHHA1 domain Mt_ATP-synt_D PF05873.12 PRP87423.1 - 1.3 8.9 7.0 2.1 8.2 5.5 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) TMPIT PF07851.13 PRP87423.1 - 2.1 7.5 8.1 2.6 7.2 8.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF948 PF06103.11 PRP87423.1 - 2.5 8.4 4.3 28 5.1 4.3 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fmp27_WPPW PF10359.9 PRP87423.1 - 4.2 6.1 12.9 5.4 5.7 12.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4407 PF14362.6 PRP87423.1 - 5 6.4 10.9 11 5.3 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) POX PF07526.11 PRP87423.1 - 6.4 7.4 7.5 3.2 8.3 3.9 1.9 1 1 1 2 2 2 0 Associated with HOX V_ATPase_I PF01496.19 PRP87423.1 - 7.5 4.3 9.3 9.1 4.0 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syja_N PF02383.18 PRP87424.1 - 8.9e-94 314.4 0.9 1.5e-93 313.6 0.9 1.4 1 0 0 1 1 1 1 SacI homology domain DUF846 PF05832.12 PRP87424.1 - 2.4 8.2 5.5 3 7.9 0.1 2.8 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF846) Ccdc124 PF06244.12 PRP87425.1 - 3.6e-38 131.0 12.9 3.6e-38 131.0 12.9 2.0 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 KBP_C PF12309.8 PRP87426.1 - 5.6e-59 200.5 0.4 8.7e-59 199.8 0.4 1.3 1 0 0 1 1 1 1 KIF-1 binding protein C terminal Dynamin_N PF00350.23 PRP87427.1 - 9.1e-22 77.9 12.6 1.9e-21 76.9 0.2 4.0 4 1 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 PRP87427.1 - 2.8e-11 43.5 0.1 2.1e-10 40.7 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP87427.1 - 3.4e-06 26.8 1.5 1.6e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP87427.1 - 0.00039 20.4 0.3 0.18 11.7 0.0 3.3 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 PRP87427.1 - 0.0051 16.3 0.3 1.2 8.7 0.1 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 PRP87427.1 - 0.0073 15.6 0.8 0.18 11.0 0.0 2.9 3 0 0 3 3 3 1 Septin ATP_bind_1 PF03029.17 PRP87427.1 - 0.0094 15.8 1.0 5.1 6.8 0.0 3.2 3 1 0 3 3 3 2 Conserved hypothetical ATP binding protein Roc PF08477.13 PRP87427.1 - 0.029 14.6 0.3 2.8 8.2 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 PRP87427.1 - 0.041 13.2 4.4 2.2 7.6 0.2 3.0 3 0 0 3 3 3 0 AIG1 family IIGP PF05049.13 PRP87427.1 - 0.096 11.7 8.1 0.18 10.8 0.0 3.2 4 0 0 4 4 4 0 Interferon-inducible GTPase (IIGP) AAA_13 PF13166.6 PRP87427.1 - 0.88 8.1 13.4 1.1 7.8 3.0 2.2 2 0 0 2 2 2 0 AAA domain OmpH PF03938.14 PRP87427.1 - 7.8 6.8 14.0 13 6.1 4.0 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) PFEMP PF03011.15 PRP87427.1 - 8.1 7.1 8.3 8.2 7.1 0.1 3.5 3 0 0 3 3 3 0 PFEMP DBL domain NUDIX PF00293.28 PRP87429.1 - 9.7e-19 67.7 0.0 1.5e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Sigma70_r3 PF04539.16 PRP87429.1 - 0.061 13.4 1.1 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-70 region 3 DASH_Duo1 PF08651.10 PRP87431.1 - 0.024 14.4 0.1 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 TMEM190 PF15431.6 PRP87431.1 - 0.025 14.7 0.0 0.083 13.0 0.0 1.9 2 0 0 2 2 2 0 Transmembrane protein 190 Peptidase_C1 PF00112.23 PRP87432.1 - 1.2e-67 228.2 0.4 9.8e-67 225.2 0.2 2.8 2 0 0 2 2 2 1 Papain family cysteine protease RNase_T PF00929.24 PRP87432.1 - 7.6e-21 75.4 5.4 6.5e-20 72.3 0.0 4.0 3 0 0 3 3 3 1 Exonuclease Inhibitor_I29 PF08246.12 PRP87432.1 - 3.1e-12 46.8 1.1 3.1e-12 46.8 1.1 3.9 3 0 0 3 3 3 1 Cathepsin propeptide inhibitor domain (I29) Gelsolin PF00626.22 PRP87434.1 - 1e-53 179.2 38.8 2.7e-12 46.4 0.0 9.7 11 0 0 11 11 11 7 Gelsolin repeat LRR_8 PF13855.6 PRP87434.1 - 6.3e-17 61.1 27.5 1.2e-06 28.2 7.2 4.9 3 2 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 PRP87434.1 - 2.6e-15 56.3 31.5 4.8e-05 23.6 3.2 5.2 4 1 1 6 6 6 5 Leucine Rich repeats (2 copies) PH PF00169.29 PRP87434.1 - 1.4e-12 48.0 0.2 9.2e-12 45.4 0.2 2.5 1 0 0 1 1 1 1 PH domain VHP PF02209.19 PRP87434.1 - 3.5e-12 46.2 0.3 1.4e-11 44.3 0.3 2.2 1 0 0 1 1 1 1 Villin headpiece domain CBM77 PF18283.1 PRP87435.1 - 0.076 13.4 0.1 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate binding module 77 CHCH PF06747.13 PRP87436.1 - 0.062 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 CHCH domain Ras PF00071.22 PRP87438.1 - 6.7e-46 155.9 0.1 1.3e-45 154.9 0.1 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP87438.1 - 1.9e-16 60.4 0.0 2.4e-15 56.8 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase F-box-like PF12937.7 PRP87438.1 - 5.3e-09 35.8 0.1 1.3e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP87438.1 - 1e-08 34.8 0.0 2.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain MMR_HSR1 PF01926.23 PRP87438.1 - 0.00018 21.6 0.0 0.0033 17.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase F-box_4 PF15966.5 PRP87438.1 - 0.00089 19.1 0.0 0.0029 17.5 0.0 1.9 1 0 0 1 1 1 1 F-box Arf PF00025.21 PRP87438.1 - 0.0014 18.1 0.0 0.0052 16.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family TPR_19 PF14559.6 PRP87438.1 - 0.003 18.0 1.0 0.15 12.6 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PRANC PF09372.10 PRP87438.1 - 0.017 15.5 0.3 0.076 13.3 0.0 2.3 2 0 0 2 2 1 0 PRANC domain RsgA_GTPase PF03193.16 PRP87438.1 - 0.032 14.1 0.2 3.7 7.4 0.1 2.8 3 0 0 3 3 3 0 RsgA GTPase SnoaL_2 PF12680.7 PRP87438.1 - 0.044 14.4 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Glyco_trans_A_1 PF09318.10 PRP87438.1 - 0.059 13.1 0.2 0.55 9.9 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase 1 domain A TPR_14 PF13428.6 PRP87438.1 - 0.19 12.6 2.6 20 6.4 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 PRP87439.1 - 2.8e-70 236.6 0.0 3.7e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP87439.1 - 5.5e-64 211.8 112.9 6.7e-10 38.6 0.1 15.8 13 2 0 15 15 15 13 Leucine rich repeat LRR_4 PF12799.7 PRP87439.1 - 9.8e-54 178.4 121.9 2.2e-05 24.7 0.3 21.9 16 6 8 25 25 25 18 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP87439.1 - 2.1e-47 161.7 0.0 3.2e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_6 PF13516.6 PRP87439.1 - 4.9e-20 69.8 78.9 2.3 8.5 0.0 26.6 28 0 0 28 28 28 7 Leucine Rich repeat LRR_1 PF00560.33 PRP87439.1 - 4.7e-11 41.6 96.5 0.4 11.4 0.1 27.8 29 5 0 29 29 29 3 Leucine Rich Repeat Haspin_kinase PF12330.8 PRP87439.1 - 0.027 13.4 0.0 0.073 12.0 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PRP87439.1 - 0.081 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP87439.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LRR_5 PF13306.6 PRP87439.1 - 0.22 11.5 5.0 16 5.5 0.0 4.2 4 0 0 4 4 4 0 BspA type Leucine rich repeat region (6 copies) DUF962 PF06127.11 PRP87441.1 - 2.9e-06 27.3 1.5 1.1e-05 25.4 1.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) YjeF_N PF03853.15 PRP87442.1 - 3.8e-34 118.0 0.1 5.5e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 PRP87442.1 - 4.1e-06 27.6 0.6 4.1e-06 27.6 0.6 2.3 2 0 0 2 2 2 1 FDF domain Arb2 PF09757.9 PRP87442.1 - 0.0051 16.0 0.0 0.21 10.7 0.0 2.4 2 0 0 2 2 2 1 Arb2 domain THF_DHG_CYH_C PF02882.19 PRP87442.1 - 0.087 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LSM PF01423.22 PRP87442.1 - 0.15 11.7 0.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 LSM domain Pkinase PF00069.25 PRP87443.1 - 5.2e-45 153.9 0.0 6.8e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87443.1 - 1e-20 74.1 0.0 1.4e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP87443.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP87443.1 - 0.0076 15.1 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 PRP87444.1 - 3.6e-05 23.5 0.0 0.00011 21.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5327 PF17261.2 PRP87446.1 - 0.26 12.1 2.5 0.94 10.3 2.5 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5327) ABC2_membrane PF01061.24 PRP87448.1 - 8.4e-89 296.5 58.4 2.8e-50 170.7 22.7 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 PRP87448.1 - 9.5e-34 116.8 0.0 1e-18 68.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 PRP87448.1 - 3.5e-26 90.9 16.1 1.6e-21 76.0 0.2 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 PRP87448.1 - 1.4e-10 40.8 52.0 1.1e-07 31.3 19.4 3.3 2 1 1 3 3 3 2 ABC-2 family transporter protein Zeta_toxin PF06414.12 PRP87448.1 - 1.7e-05 24.2 0.5 0.035 13.4 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 PRP87448.1 - 3.2e-05 23.9 0.0 0.00092 19.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 PRP87448.1 - 3.6e-05 23.4 0.2 0.0034 17.1 0.2 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PRP87448.1 - 4.5e-05 23.4 0.0 0.0032 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PRP87448.1 - 0.00045 20.7 0.2 0.27 11.6 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 PRP87448.1 - 0.00079 19.7 0.0 0.18 12.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PRP87448.1 - 0.00099 19.3 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 PRP87448.1 - 0.0011 19.5 0.0 0.0026 18.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 PRP87448.1 - 0.017 14.7 2.3 0.027 14.0 0.3 2.3 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 PRP87448.1 - 0.036 13.8 0.0 1.2 8.8 0.4 2.4 2 0 0 2 2 2 0 AAA domain DUF3600 PF12207.8 PRP87448.1 - 0.037 14.0 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF3600) NACHT PF05729.12 PRP87448.1 - 0.041 13.8 0.1 0.7 9.8 0.3 2.3 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 PRP87448.1 - 0.053 13.8 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PRP87448.1 - 0.068 13.6 0.0 8.4 6.8 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 PRP87448.1 - 0.13 12.4 0.0 6.5 6.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 PRP87448.1 - 0.13 11.9 0.0 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2407_C PF13373.6 PRP87448.1 - 0.13 12.4 0.0 0.71 10.1 0.0 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain AAA_15 PF13175.6 PRP87448.1 - 0.2 11.3 0.0 4.1 7.0 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 PRP87448.1 - 0.35 11.4 2.7 0.37 11.3 0.0 2.3 3 0 0 3 3 2 0 AAA domain GARP PF16731.5 PRP87448.1 - 0.54 9.9 2.8 0.96 9.1 2.8 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma ABC2_membrane_2 PF12679.7 PRP87448.1 - 2.2 7.5 22.4 0.026 13.8 2.0 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein Prefoldin_2 PF01920.20 PRP87449.1 - 0.028 14.4 0.1 0.09 12.7 0.1 1.9 1 0 0 1 1 1 0 Prefoldin subunit PKcGMP_CC PF16808.5 PRP87449.1 - 0.038 13.9 0.8 0.15 11.9 0.8 2.0 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3425 PF11905.8 PRP87449.1 - 0.051 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3425) Ank_2 PF12796.7 PRP87452.1 - 2.7e-66 220.2 16.1 7.3e-15 55.3 0.3 7.8 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87452.1 - 3.4e-61 202.9 7.7 9.5e-10 38.8 0.2 10.3 7 3 4 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87452.1 - 8.5e-43 139.4 3.9 0.014 15.9 0.0 14.1 15 0 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 PRP87452.1 - 2.2e-36 123.5 8.8 2.5e-08 34.0 0.1 10.6 6 3 6 12 12 12 9 Ankyrin repeats (many copies) Ank PF00023.30 PRP87452.1 - 2.8e-34 116.1 22.3 3.7e-05 24.0 0.0 13.8 13 2 0 13 13 13 7 Ankyrin repeat SAM_2 PF07647.17 PRP87452.1 - 7.2e-06 26.0 0.1 2.3e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP87452.1 - 0.00031 21.1 0.1 0.0012 19.3 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PRP87452.1 - 0.0011 18.9 0.0 0.004 17.1 0.0 2.0 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain F-box PF00646.33 PRP87452.1 - 0.0041 17.0 0.1 0.01 15.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP87452.1 - 0.082 12.8 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.7 PRP87453.1 - 0.0093 16.5 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) GCFC PF07842.12 PRP87457.1 - 0.0073 15.9 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein GCFC PF07842.12 PRP87458.1 - 6.9e-13 48.8 12.3 5.6e-12 45.8 12.3 2.0 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 PRP87458.1 - 0.0044 16.9 0.7 0.01 15.7 0.7 1.7 1 0 0 1 1 1 1 G-patch domain EMP24_GP25L PF01105.24 PRP87459.1 - 3.7e-29 101.9 0.1 1.1e-28 100.4 0.1 1.7 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LRR_8 PF13855.6 PRP87460.1 - 2e-62 206.9 253.8 5.1e-08 32.6 6.0 14.5 5 3 15 20 20 20 20 Leucine rich repeat LRR_4 PF12799.7 PRP87460.1 - 8.7e-49 162.7 163.7 3.7e-06 27.2 0.9 17.8 8 3 9 21 21 20 17 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP87460.1 - 3.2e-29 102.0 1.0 4.5e-29 101.5 1.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87460.1 - 3.3e-21 75.8 0.6 5.4e-21 75.1 0.6 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_1 PF00560.33 PRP87460.1 - 3.3e-11 42.1 162.7 0.27 11.9 0.1 28.7 30 1 0 30 30 29 11 Leucine Rich Repeat GPS PF01825.21 PRP87460.1 - 7.8e-10 39.1 1.1 2e-09 37.8 1.1 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Papilloma_E5A PF05776.12 PRP87460.1 - 0.0046 17.3 1.1 0.017 15.5 1.1 2.0 1 0 0 1 1 1 1 Papillomavirus E5A protein Orf78 PF06024.12 PRP87460.1 - 0.073 13.4 1.1 0.13 12.5 0.2 1.8 2 0 0 2 2 2 0 Orf78 (ac78) TMEM154 PF15102.6 PRP87460.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.4 2 0 0 2 2 2 0 TMEM154 protein family SKG6 PF08693.10 PRP87460.1 - 0.27 10.7 5.1 0.66 9.4 5.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 PRP87460.1 - 0.58 10.1 4.0 1.3 8.9 4.0 1.5 1 0 0 1 1 1 0 Syndecan domain SRRM_C PF15230.6 PRP87463.1 - 0.041 14.4 1.9 0.041 14.4 1.9 1.9 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus STAG PF08514.11 PRP87464.1 - 4.5e-24 84.5 3.8 4.6e-22 78.1 1.2 2.8 2 0 0 2 2 2 2 STAG domain HEAT PF02985.22 PRP87464.1 - 1.8e-06 27.7 0.0 0.022 15.0 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat DUF3535 PF12054.8 PRP87464.1 - 2.6e-06 27.0 0.3 5.3e-05 22.7 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) HEAT_2 PF13646.6 PRP87464.1 - 0.00011 22.5 0.0 0.015 15.7 0.0 3.1 1 1 2 3 3 3 2 HEAT repeats RasGEF_N PF00618.20 PRP87464.1 - 0.00026 21.2 0.9 0.19 12.0 0.1 3.3 2 1 1 3 3 3 1 RasGEF N-terminal motif Cnd1 PF12717.7 PRP87464.1 - 0.00056 20.0 0.5 0.0051 16.9 0.2 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 PriC PF07445.12 PRP87464.1 - 0.025 14.5 1.8 0.042 13.8 0.4 2.0 2 0 0 2 2 2 0 Primosomal replication protein priC CsgE PF10627.9 PRP87464.1 - 0.038 14.2 2.7 4.3 7.6 0.1 3.4 2 1 0 2 2 2 0 Curli assembly protein CsgE DUF2385 PF09539.10 PRP87464.1 - 0.09 13.3 0.1 0.3 11.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) PdaC PF13739.6 PRP87464.1 - 9.5 7.3 8.6 4.5 8.3 0.4 3.7 3 1 0 3 3 3 0 Deacetylase PdaC LRR_6 PF13516.6 PRP87466.1 - 2.6e-42 139.3 39.0 6.1e-06 25.9 0.2 13.0 13 0 0 13 13 13 10 Leucine Rich repeat LRR_4 PF12799.7 PRP87466.1 - 4.1e-10 39.7 30.7 0.0096 16.3 0.2 7.9 3 2 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP87466.1 - 3.7e-08 32.8 0.1 33 5.6 0.0 8.9 10 0 0 10 10 10 0 Leucine Rich Repeat FAS_meander PF17951.1 PRP87466.1 - 0.00029 20.7 0.1 0.038 13.8 0.0 2.9 3 0 0 3 3 3 1 Fatty acid synthase meander beta sheet domain F-box-like PF12937.7 PRP87466.1 - 0.00039 20.2 0.1 0.00096 19.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like Apo-CII PF05355.11 PRP87466.1 - 0.026 14.7 14.9 2.7 8.2 0.1 6.5 3 2 6 9 9 9 0 Apolipoprotein C-II F-box PF00646.33 PRP87466.1 - 0.059 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 PRP87466.1 - 0.098 12.4 34.1 5 7.0 1.0 8.2 2 2 7 9 9 9 0 Leucine rich repeat TyrRSs_C PF16714.5 PRP87466.1 - 0.84 9.5 2.8 26 4.6 0.0 3.8 4 0 0 4 4 4 0 Tyrosyl-tRNA synthetase C-terminal domain Cellulase PF00150.18 PRP87468.1 - 1.3e-17 64.2 3.2 1.9e-17 63.7 3.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cupin_2 PF07883.11 PRP87469.1 - 4.9e-08 32.6 0.9 9e-08 31.7 0.9 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 PRP87469.1 - 0.018 14.7 0.1 0.075 12.6 0.2 2.0 2 1 0 2 2 2 0 Cupin AraC_binding PF02311.19 PRP87469.1 - 0.14 12.1 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Pkinase_Tyr PF07714.17 PRP87471.1 - 7.2e-50 169.7 0.0 1.1e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87471.1 - 7e-33 114.1 0.0 1.2e-32 113.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Beta_helix PF13229.6 PRP87471.1 - 7.2e-16 58.4 82.6 2e-08 34.2 8.7 6.5 1 1 5 6 6 6 5 Right handed beta helix region Herpes_U55 PF06501.11 PRP87471.1 - 0.00084 18.2 0.1 0.084 11.6 0.0 2.3 2 0 0 2 2 2 2 Human herpesvirus U55 protein Kinase-like PF14531.6 PRP87471.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP87471.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chlam_PMP PF02415.17 PRP87471.1 - 0.022 15.2 1.7 0.022 15.2 1.7 16.9 19 2 0 19 19 19 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Adeno_E1B_55K PF01696.17 PRP87471.1 - 0.092 11.4 4.1 0.43 9.2 0.4 3.2 2 1 0 2 2 2 0 Adenovirus EB1 55K protein / large t-antigen Cellulase PF00150.18 PRP87472.1 - 6.7e-37 127.4 16.3 4.9e-20 72.1 5.5 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) LPD28 PF18843.1 PRP87472.1 - 0.17 11.5 0.1 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Large polyvalent protein associated domain 28 Glyco_hydro_42 PF02449.15 PRP87472.1 - 0.21 10.9 4.5 9.6 5.4 0.3 3.6 2 2 2 4 4 4 0 Beta-galactosidase Sin3_corepress PF08295.12 PRP87472.1 - 0.24 11.5 0.4 13 5.9 0.1 2.7 3 0 0 3 3 3 0 Sin3 family co-repressor JmjN PF02375.17 PRP87472.1 - 0.55 10.2 1.6 38 4.3 0.2 2.7 2 0 0 2 2 2 0 jmjN domain Vps55 PF04133.14 PRP87474.1 - 2.7e-36 124.1 6.8 2.7e-36 124.1 6.8 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting 55 DUF3487 PF11990.8 PRP87474.1 - 1 9.3 8.3 2.6 8.0 2.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) DUF4231 PF14015.6 PRP87474.1 - 1.2 9.7 7.4 1.2 9.7 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Ammonium_transp PF00909.21 PRP87475.1 - 8.8e-108 360.5 25.3 1.1e-107 360.3 25.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Robl_LC7 PF03259.17 PRP87475.1 - 0.064 13.0 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Roadblock/LC7 domain EMP70 PF02990.16 PRP87475.1 - 0.14 10.8 3.6 0.23 10.1 3.6 1.3 1 0 0 1 1 1 0 Endomembrane protein 70 EHN PF06441.12 PRP87476.1 - 2.1e-33 114.9 2.4 1.3e-32 112.4 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 PRP87476.1 - 1.6e-08 34.5 0.3 3e-08 33.6 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP87476.1 - 5.7e-05 23.8 1.3 0.00018 22.2 1.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Guanylate_cyc PF00211.20 PRP87478.1 - 1.1e-33 116.4 0.2 2.5e-33 115.2 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Zn_clus PF00172.18 PRP87480.1 - 1.8e-06 28.0 11.7 3e-06 27.2 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 PRP87480.1 - 0.0086 16.1 0.2 0.025 14.6 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 PRP87480.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.7 PRP87480.1 - 0.1 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 PAS domain MLTR_LBD PF17765.1 PRP87480.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain SKG6 PF08693.10 PRP87480.1 - 6.3 6.3 6.0 13 5.3 6.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Aldo_ket_red PF00248.21 PRP87481.1 - 1.7e-38 132.5 0.0 2.8e-38 131.8 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.13 PRP87482.1 - 1.4e-26 93.4 10.8 5.1e-26 91.6 10.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Homeobox_KN PF05920.11 PRP87483.1 - 3e-09 36.6 0.3 8.9e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 PRP87483.1 - 4e-07 29.8 0.1 7.8e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Homeodomain COX17 PF05051.13 PRP87484.1 - 0.025 14.9 1.1 0.057 13.8 1.1 1.7 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 PRP87484.1 - 0.028 14.6 2.0 0.13 12.5 2.0 1.9 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.12 PRP87484.1 - 0.22 11.8 3.8 0.36 11.1 3.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF3128 PF11326.8 PRP87484.1 - 0.4 11.1 5.4 0.21 12.0 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) DUF3915 PF13054.6 PRP87484.1 - 0.41 10.6 5.0 0.43 10.6 3.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) FlaC_arch PF05377.11 PRP87485.1 - 0.14 12.5 0.1 0.41 11.1 0.1 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) LCAT PF02450.15 PRP87486.1 - 2.6e-05 23.6 0.0 3.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 PRP87486.1 - 0.00019 22.1 0.0 0.00037 21.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 PRP87486.1 - 0.00069 19.4 0.1 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 PRP87486.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 PRP87486.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.12 PRP87486.1 - 0.034 13.7 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 PRP87486.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Glyco_hydro_18 PF00704.28 PRP87487.1 - 7.6e-18 65.3 5.9 2e-17 63.9 5.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PAN_4 PF14295.6 PRP87487.1 - 7.9e-10 38.5 5.2 7.9e-10 38.5 5.2 3.4 3 1 1 4 4 4 1 PAN domain Chitin_bind_1 PF00187.19 PRP87487.1 - 1.8e-06 28.3 22.4 1.8e-06 28.3 22.4 2.6 2 1 0 2 2 2 1 Chitin recognition protein PAN_2 PF08276.11 PRP87487.1 - 0.00054 20.0 3.7 0.00054 20.0 3.7 2.1 2 0 0 2 2 2 1 PAN-like domain PAN_3 PF08277.12 PRP87487.1 - 3.9 7.4 9.7 0.056 13.3 1.3 2.2 2 0 0 2 2 2 0 PAN-like domain HNH_2 PF13391.6 PRP87489.1 - 5.5e-08 32.8 1.8 8.3e-08 32.3 0.1 2.2 2 0 0 2 2 2 1 HNH endonuclease K_trans PF02705.16 PRP87490.1 - 1.1e-98 331.1 18.1 1.4e-98 330.7 18.1 1.1 1 0 0 1 1 1 1 K+ potassium transporter Mito_carr PF00153.27 PRP87491.1 - 8.1e-60 198.8 3.0 3.7e-22 78.1 0.1 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein Alpha-amylase PF00128.24 PRP87495.1 - 3.1e-24 86.2 0.3 2.3e-23 83.3 0.3 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 PRP87495.1 - 2.4e-07 29.4 0.1 0.0052 15.1 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 PRP87495.1 - 0.14 12.4 0.2 0.41 10.9 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) B_lectin PF01453.24 PRP87496.1 - 7.9e-05 23.1 0.1 0.16 12.5 0.0 2.6 1 1 1 2 2 2 2 D-mannose binding lectin GATA PF00320.27 PRP87497.1 - 2.1e-09 36.8 5.2 2.1e-09 36.8 5.2 2.6 2 1 0 2 2 2 1 GATA zinc finger CLIP1_ZNF PF16641.5 PRP87497.1 - 0.00046 20.0 1.8 0.0061 16.4 0.7 2.8 2 0 0 2 2 2 1 CLIP1 zinc knuckle C1_1 PF00130.22 PRP87497.1 - 0.0069 16.2 20.3 0.47 10.4 7.9 3.2 1 1 2 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 PRP87497.1 - 0.0072 16.2 11.5 0.0072 16.2 11.5 2.9 2 1 0 2 2 2 1 PHD-finger zf-ribbon_3 PF13248.6 PRP87497.1 - 0.0082 15.5 7.6 2.4 7.7 0.0 4.3 4 0 0 4 4 4 1 zinc-ribbon domain Vps36-NZF-N PF16988.5 PRP87497.1 - 0.1 12.0 5.2 14 5.2 0.4 3.3 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PHD_Oberon PF07227.11 PRP87497.1 - 0.15 11.9 14.1 0.058 13.3 11.3 1.6 2 1 0 2 2 2 0 PHD - plant homeodomain finger protein Prok-RING_1 PF14446.6 PRP87497.1 - 0.17 11.9 19.5 0.53 10.2 9.2 3.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PHD_3 PF13922.6 PRP87497.1 - 3.1 8.2 8.0 0.63 10.5 0.4 2.9 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx PHD_4 PF16866.5 PRP87497.1 - 9.2 6.4 14.7 1.3e+02 2.8 0.2 2.5 1 1 1 2 2 2 0 PHD-finger 2-Hacid_dh_C PF02826.19 PRP87498.1 - 3.8e-54 182.7 0.1 5.3e-54 182.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PRP87498.1 - 1.4e-27 96.0 0.1 1.8e-27 95.6 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PRP87498.1 - 5.4e-06 26.7 0.0 1.7e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 PRP87498.1 - 0.00099 19.2 0.1 0.0022 18.1 0.0 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 PRP87498.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 PRP87498.1 - 0.065 13.3 0.4 0.79 9.8 0.1 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 PRP87498.1 - 0.078 12.9 0.2 0.26 11.2 0.2 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dak1 PF02733.17 PRP87499.1 - 1e-106 356.3 0.2 1.6e-106 355.8 0.2 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 PRP87499.1 - 4.2e-47 160.3 3.1 6.1e-47 159.7 3.1 1.2 1 0 0 1 1 1 1 DAK2 domain IU_nuc_hydro PF01156.19 PRP87499.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase zf-MYND PF01753.18 PRP87500.1 - 1.2e-09 38.1 16.6 2.2e-09 37.2 16.6 1.5 1 0 0 1 1 1 1 MYND finger CDT1_C PF16679.5 PRP87500.1 - 0.008 16.6 0.2 0.039 14.4 0.2 2.2 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Gal11_ABD1 PF18535.1 PRP87500.1 - 0.066 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) HAMP PF00672.25 PRP87500.1 - 0.16 12.4 0.1 0.7 10.3 0.0 2.0 2 0 0 2 2 2 0 HAMP domain zf-CCHC_5 PF14787.6 PRP87500.1 - 2.6 7.8 9.7 3.6 7.4 8.2 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger PolC_DP2 PF03833.13 PRP87500.1 - 4.5 5.0 8.7 6.2 4.6 8.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 GTP_EFTU PF00009.27 PRP87501.1 - 6.3e-55 185.7 0.0 1e-54 185.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PRP87501.1 - 3.8e-40 136.7 0.0 8.7e-40 135.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PRP87501.1 - 3.6e-13 49.7 0.4 8.8e-13 48.5 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PRP87501.1 - 8.1e-05 22.7 0.1 0.0033 17.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP87501.1 - 0.0018 17.7 0.0 0.0043 16.4 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU_D4 PF14578.6 PRP87501.1 - 0.015 15.2 1.1 0.026 14.4 0.2 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 CbiM PF01891.16 PRP87502.1 - 0.00073 19.4 3.2 0.0012 18.8 3.2 1.3 1 0 0 1 1 1 1 Cobalt uptake substrate-specific transmembrane region DUF1211 PF06736.11 PRP87502.1 - 2.7 8.5 10.1 10 6.6 10.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) E1_dh PF00676.20 PRP87503.1 - 4e-99 331.3 0.1 5e-99 331.0 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PRP87503.1 - 0.0074 15.5 0.0 0.031 13.5 0.0 1.9 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DUF4200 PF13863.6 PRP87504.1 - 2.7e-25 89.1 21.8 2.7e-25 89.1 21.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) Choline_kin_N PF04428.14 PRP87504.1 - 0.073 12.8 0.0 0.6 9.8 0.0 2.4 2 1 0 2 2 2 0 Choline kinase N terminus zf-CCCH PF00642.24 PRP87505.1 - 1.1e-10 41.1 3.4 2.3e-10 40.1 3.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 PRP87505.1 - 4.8e-08 32.9 4.2 4.8e-08 32.9 4.2 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP87505.1 - 1.8e-07 31.0 8.0 3.2e-07 30.2 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PRP87505.1 - 2.4e-06 27.3 6.9 4.4e-06 26.5 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PRP87505.1 - 2.7e-06 27.1 6.8 5e-06 26.3 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP87505.1 - 4.7e-06 26.3 8.8 8.6e-06 25.5 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 PRP87505.1 - 5.7e-06 26.2 5.2 1.2e-05 25.2 5.2 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4 PF00097.25 PRP87505.1 - 3.6e-05 23.5 8.6 7.9e-05 22.5 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP87505.1 - 0.0001 22.5 9.3 0.0002 21.6 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 PRP87505.1 - 0.00081 19.5 6.5 0.0055 16.8 6.8 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 PRP87505.1 - 0.001 18.8 3.3 0.0021 17.8 3.3 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RING_10 PF16685.5 PRP87505.1 - 0.0057 16.8 4.5 0.0057 16.8 4.5 1.9 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-CCCH_2 PF14608.6 PRP87505.1 - 0.045 14.2 1.6 0.1 13.1 1.6 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-HIT PF04438.16 PRP87505.1 - 0.18 11.7 4.7 0.17 11.8 0.7 2.6 2 0 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.8 PRP87505.1 - 1.9 8.4 7.6 5.2 7.0 7.6 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Polyketide_cyc2 PF10604.9 PRP87506.1 - 1.3e-08 35.2 0.2 1.5e-08 35.0 0.2 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 PRP87506.1 - 0.0069 16.6 0.4 0.0099 16.1 0.4 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Exo_endo_phos PF03372.23 PRP87507.1 - 2.8e-06 27.0 0.0 5.6e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UCH PF00443.29 PRP87509.1 - 7.1e-45 153.5 2.4 7.1e-45 153.5 2.4 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP87509.1 - 2.4e-35 122.7 4.0 2.4e-35 122.7 4.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 PRP87509.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family CybS PF05328.12 PRP87510.1 - 1.9e-12 47.0 0.1 2.5e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit LtrA PF06772.11 PRP87510.1 - 0.037 13.3 1.0 0.051 12.8 1.0 1.1 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) Ank_2 PF12796.7 PRP87511.1 - 8e-43 144.9 5.7 6.9e-11 42.6 0.0 5.5 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87511.1 - 1.5e-35 121.1 0.1 2.7e-06 27.8 0.0 8.7 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87511.1 - 2.5e-28 95.0 5.4 0.0016 18.8 0.0 10.9 11 2 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 PRP87511.1 - 2.1e-26 91.6 0.1 3.3e-06 27.3 0.0 6.7 5 1 1 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP87511.1 - 4.9e-25 86.8 0.0 0.0044 17.4 0.0 10.4 9 1 0 9 9 9 6 Ankyrin repeat HetR_C PF18460.1 PRP87511.1 - 0.12 12.3 2.3 0.55 10.2 1.0 2.4 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain UvrB PF12344.8 PRP87511.1 - 4.4 7.2 6.6 19 5.2 0.3 3.3 3 0 0 3 3 3 0 Ultra-violet resistance protein B Atx10homo_assoc PF09759.9 PRP87512.1 - 3.5e-32 110.4 0.2 3.5e-32 110.4 0.2 3.9 6 0 0 6 6 6 1 Spinocerebellar ataxia type 10 protein domain Importin_rep_3 PF18806.1 PRP87512.1 - 0.038 14.0 0.5 20 5.3 0.0 3.1 3 0 0 3 3 3 0 Importin 13 repeat PDEase_I PF00233.19 PRP87513.1 - 1.7e-71 240.8 6.3 1.7e-71 240.8 6.3 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF3910 PF13049.6 PRP87513.1 - 0.019 15.3 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3910) 4HB_MCP_1 PF12729.7 PRP87513.1 - 0.2 11.2 3.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction FliT PF05400.13 PRP87513.1 - 0.69 10.8 4.6 5.3 7.9 0.8 3.3 3 0 0 3 3 3 0 Flagellar protein FliT DDE_3 PF13358.6 PRP87514.1 - 1.1e-07 31.7 0.1 2.6e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease Elongin_A PF06881.11 PRP87515.1 - 0.031 14.8 1.6 0.031 14.8 1.6 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Importin_rep_6 PF18829.1 PRP87515.1 - 0.16 12.1 0.5 0.36 11.0 0.5 1.6 1 0 0 1 1 1 0 Importin repeat 6 DUF2222 PF09984.9 PRP87516.1 - 0.021 14.7 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) DUF3932 PF13068.6 PRP87518.1 - 0.16 12.2 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) MS_channel PF00924.18 PRP87519.1 - 4.5e-12 46.0 0.1 6.5e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel HNH_2 PF13391.6 PRP87521.1 - 3.4e-07 30.3 1.0 6.5e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease LEA_4 PF02987.16 PRP87524.1 - 1.4e-92 303.6 422.2 7.3e-06 26.0 5.8 29.6 8 5 24 32 32 32 30 Late embryogenesis abundant protein Apolipoprotein PF01442.18 PRP87524.1 - 2.6e-39 135.1 264.3 9.9e-10 38.6 34.6 10.9 3 2 11 14 14 14 12 Apolipoprotein A1/A4/E domain YtxH PF12732.7 PRP87524.1 - 2e-34 118.0 330.8 0.0029 18.1 14.6 22.1 3 3 15 18 18 18 13 YtxH-like protein DUF883 PF05957.13 PRP87524.1 - 2.5e-12 47.2 256.6 0.068 13.8 3.8 22.0 4 2 22 28 28 28 24 Bacterial protein of unknown function (DUF883) FOP_dimer PF09398.10 PRP87525.1 - 1.2e-10 41.5 0.1 3.9e-10 39.9 0.1 2.0 1 1 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 PRP87525.1 - 1.2e-05 24.2 0.1 2.3e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 LisH PAP_assoc PF03828.19 PRP87525.1 - 1.6 9.0 3.3 1.7 8.9 1.0 2.2 2 0 0 2 2 2 0 Cid1 family poly A polymerase Cyclin_N PF00134.23 PRP87526.1 - 3.2e-10 39.9 1.0 3.7e-09 36.4 0.6 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP87526.1 - 2.3e-06 27.7 0.2 9.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 PRP87526.1 - 8.7e-05 22.5 0.7 0.17 12.0 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 PRP87526.1 - 0.018 15.4 0.0 0.076 13.4 0.0 2.0 2 1 0 2 2 2 0 Cyclin C-terminal domain CBF PF03914.17 PRP87526.1 - 0.31 11.1 1.5 1.8 8.6 1.4 2.1 1 1 0 1 1 1 0 CBF/Mak21 family Ras PF00071.22 PRP87528.1 - 2.7e-58 196.2 0.0 3.8e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Mpv17_PMP22 PF04117.12 PRP87528.1 - 3.6e-21 75.1 0.1 9.7e-21 73.8 0.1 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family Roc PF08477.13 PRP87528.1 - 2.1e-20 73.2 0.0 3.4e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP87528.1 - 1.1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP87528.1 - 6.7e-06 25.8 0.2 3.7e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP87528.1 - 0.00041 20.4 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP87528.1 - 0.0045 16.9 0.4 3.2 7.6 0.3 2.4 1 1 0 2 2 2 2 RsgA GTPase YebO PF13974.6 PRP87529.1 - 4.1 7.5 7.3 2.3 8.3 4.8 1.9 2 0 0 2 2 2 0 YebO-like protein CytochromB561_N PF09786.9 PRP87530.1 - 6.2e-32 111.3 11.6 1.7e-30 106.6 11.6 2.2 1 1 0 1 1 1 1 Cytochrome B561, N terminal Tmemb_14 PF03647.13 PRP87530.1 - 2.8e-06 28.0 10.0 2.8e-06 28.0 10.0 1.9 2 0 0 2 2 2 1 Transmembrane proteins 14C NPCC PF08058.11 PRP87530.1 - 0.016 15.3 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore complex component DnaJ PF00226.31 PRP87531.1 - 2.9e-24 85.0 3.2 3.9e-24 84.6 2.2 1.8 2 0 0 2 2 2 1 DnaJ domain zf-MYND PF01753.18 PRP87531.1 - 1.5e-09 37.8 19.2 2.7e-09 36.9 19.2 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 PRP87531.1 - 3.6 7.7 12.4 18 5.5 12.4 2.2 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 CDC45 PF02724.14 PRP87531.1 - 6.8 4.9 5.8 12 4.1 5.8 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_8 PF13181.6 PRP87532.1 - 3.3e-16 58.1 7.1 1.8e-06 27.7 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP87532.1 - 1.7e-15 55.8 6.4 9.7e-07 28.4 0.2 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP87532.1 - 2.7e-14 53.4 0.1 0.00069 20.1 0.1 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP87532.1 - 1.2e-13 50.2 4.0 1.1e-06 28.2 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PRP87532.1 - 5.9e-13 48.9 2.3 8.3e-05 22.8 0.1 4.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP87532.1 - 7.7e-13 47.5 1.7 0.0014 18.5 0.0 5.8 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP87532.1 - 1.5e-12 47.2 0.4 0.06 14.2 0.0 5.8 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 PRP87532.1 - 4.9e-12 46.3 0.0 0.0012 19.5 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP87532.1 - 8.4e-12 44.6 1.0 0.011 16.1 0.0 4.8 6 0 0 6 6 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP87532.1 - 2.7e-10 39.8 2.5 0.00012 21.7 0.8 4.1 3 1 1 4 4 4 3 TPR repeat TPR_10 PF13374.6 PRP87532.1 - 2.3e-09 36.8 7.3 0.0017 18.2 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP87532.1 - 1.3e-08 35.0 0.6 1.2e-05 25.4 0.1 3.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Lipase_GDSL PF00657.22 PRP87532.1 - 8.1e-08 32.5 0.2 7.2e-06 26.1 0.0 2.9 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase TPR_6 PF13174.6 PRP87532.1 - 6.8e-07 29.5 0.7 0.31 11.8 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP87532.1 - 1.3e-05 24.8 2.4 0.15 11.4 0.1 3.4 1 1 1 3 3 3 2 MalT-like TPR region TPR_20 PF14561.6 PRP87532.1 - 0.0002 21.7 3.3 0.49 10.8 0.2 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 PRP87532.1 - 0.00062 19.1 0.4 0.037 13.2 0.3 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 PRP87532.1 - 0.0034 17.8 0.2 0.017 15.6 0.2 2.2 1 1 0 1 1 1 1 Bacterial transcriptional activator domain Lipase_GDSL_2 PF13472.6 PRP87532.1 - 0.017 15.6 0.0 0.095 13.1 0.0 2.2 3 0 0 3 3 2 0 GDSL-like Lipase/Acylhydrolase family PPR PF01535.20 PRP87532.1 - 0.025 14.8 1.0 4.1 7.9 0.0 3.8 4 0 0 4 4 4 0 PPR repeat ANAPC5 PF12862.7 PRP87532.1 - 0.04 14.0 0.1 0.18 11.9 0.1 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_3 PF07720.12 PRP87532.1 - 0.061 13.3 0.4 0.061 13.3 0.4 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat RNaseH_like PF04308.12 PRP87532.1 - 0.08 12.9 1.4 0.16 11.9 0.0 2.2 3 0 0 3 3 2 0 Ribonuclease H-like DUF3856 PF12968.7 PRP87532.1 - 0.09 12.9 0.6 7.1 6.7 0.0 3.4 3 1 1 4 4 3 0 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 PRP87532.1 - 0.098 12.4 4.6 2.2 7.9 1.3 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat-like domain Rapsyn_N PF10579.9 PRP87532.1 - 0.11 12.5 1.2 18 5.5 0.1 3.5 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region DUF5102 PF17104.5 PRP87532.1 - 0.6 10.1 5.2 0.22 11.5 2.5 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF5102) MIT PF04212.18 PRP87532.1 - 3.7 7.7 19.3 8.5 6.5 0.2 6.2 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Ferritin PF00210.24 PRP87532.1 - 9.7 6.1 9.3 0.49 10.3 0.3 3.4 5 0 0 5 5 3 0 Ferritin-like domain UPF0047 PF01894.17 PRP87533.1 - 6.1e-29 100.5 0.0 1e-28 99.8 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 adh_short PF00106.25 PRP87534.1 - 1e-15 57.7 4.3 2.1e-15 56.7 0.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP87534.1 - 4e-08 33.1 3.6 1.3e-07 31.4 0.6 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP87534.1 - 0.00034 20.6 0.7 0.00073 19.5 0.7 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP87534.1 - 0.00056 19.8 0.2 0.0008 19.3 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Pro_isomerase PF00160.21 PRP87535.1 - 2.3e-45 154.7 0.0 5.1e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 PRP87535.1 - 2.5e-09 36.9 0.6 2.5e-09 36.9 0.6 2.9 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 PRP87535.1 - 1.9e-06 28.0 0.1 5.6e-05 23.2 0.0 2.5 1 1 1 2 2 2 1 U-box domain zf-Nse PF11789.8 PRP87535.1 - 0.00079 19.2 0.2 1.9 8.4 0.0 2.8 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 PRP87535.1 - 0.00084 19.4 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 PRP87535.1 - 0.031 14.3 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Ceramidase PF05875.12 PRP87537.1 - 5.1e-48 163.8 12.7 6.4e-48 163.5 12.7 1.1 1 0 0 1 1 1 1 Ceramidase TPR_12 PF13424.6 PRP87538.1 - 1.2e-35 121.6 17.5 5.4e-12 45.8 0.0 6.9 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 PRP87538.1 - 3e-12 45.6 20.7 0.022 14.9 0.8 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 PRP87538.1 - 1.5e-11 43.6 21.2 0.00084 19.1 0.2 8.1 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP87538.1 - 1.1e-09 37.8 30.7 0.0016 18.5 0.1 8.7 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 PRP87538.1 - 1.8e-09 37.6 12.8 2.3 9.3 0.4 8.9 8 2 2 10 10 9 2 Tetratricopeptide repeat SNAP PF14938.6 PRP87538.1 - 3.3e-09 36.6 26.8 0.013 14.9 0.3 4.3 1 1 4 5 5 5 3 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 PRP87538.1 - 3.6e-09 36.2 13.3 0.031 14.1 0.0 7.7 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP87538.1 - 3.9e-09 35.9 16.2 0.1 12.7 0.1 8.0 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 PRP87538.1 - 5.1e-09 36.5 19.8 0.036 14.6 0.2 7.2 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP87538.1 - 2.9e-08 33.5 8.7 4.6e-05 22.9 0.7 3.3 1 1 2 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 PRP87538.1 - 8.5e-07 29.5 9.8 0.0039 17.8 0.1 6.0 7 1 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PRP87538.1 - 3.3e-05 24.3 12.6 0.47 11.2 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat RPN7 PF10602.9 PRP87538.1 - 0.00038 20.2 20.3 0.01 15.6 2.1 4.3 2 2 0 3 3 3 2 26S proteasome subunit RPN7 Ter PF05472.11 PRP87538.1 - 0.00041 19.5 0.3 0.001 18.2 0.3 1.6 1 0 0 1 1 1 1 DNA replication terminus site-binding protein (Ter protein) ANAPC5 PF12862.7 PRP87538.1 - 0.0013 18.8 14.7 0.004 17.2 0.4 5.4 1 1 1 4 4 4 1 Anaphase-promoting complex subunit 5 PHM7_cyt PF14703.6 PRP87538.1 - 0.0013 19.0 6.6 0.025 14.8 0.0 3.7 1 1 1 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter HHH_8 PF14716.6 PRP87538.1 - 0.015 15.7 3.8 0.41 11.1 0.2 3.6 4 0 0 4 4 2 0 Helix-hairpin-helix domain Hydrolase PF00702.26 PRP87538.1 - 0.019 15.3 0.9 0.048 13.9 0.5 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase ANAPC3 PF12895.7 PRP87538.1 - 0.023 14.9 17.1 0.13 12.5 1.3 5.2 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PRP87538.1 - 0.082 12.6 7.6 5.6 6.7 0.2 5.3 6 0 0 6 6 5 0 TPR repeat DIMCO_N PF16844.5 PRP87538.1 - 0.12 12.8 1.5 3.5 8.0 0.5 2.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Vta1_C PF18097.1 PRP87538.1 - 2.3 8.0 9.3 2.3 8.0 2.1 3.9 4 0 0 4 4 3 0 Vta1 C-terminal domain DUF2753 PF10952.8 PRP87538.1 - 2.9 8.0 8.7 0.51 10.5 0.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2753) BTAD PF03704.17 PRP87538.1 - 3.2 8.2 8.6 22 5.4 0.0 4.5 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Fic PF02661.18 PRP87539.1 - 1.6e-11 45.0 0.0 6.7e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 Fic/DOC family HEAT_2 PF13646.6 PRP87541.1 - 0.00024 21.4 0.7 0.00079 19.8 0.1 2.1 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 PRP87541.1 - 0.0051 17.0 2.1 0.14 12.5 0.0 3.6 5 0 0 5 5 5 1 HEAT repeat p450 PF00067.22 PRP87542.1 - 5.1e-68 229.9 0.0 6.4e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transp_inhibit PF18791.1 PRP87543.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain EF-hand_8 PF13833.6 PRP87545.1 - 0.0047 16.7 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Prenyltrans PF00432.21 PRP87545.1 - 0.054 13.2 0.1 0.99 9.2 0.0 2.8 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat DUF4758 PF15950.5 PRP87545.1 - 0.057 13.8 0.0 0.95 9.8 0.0 2.3 1 1 1 2 2 2 0 Putative sperm flagellar membrane protein DUF507 PF04368.13 PRP87545.1 - 0.17 11.8 0.1 2.2 8.2 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF507) Beta-Casp PF10996.8 PRP87546.1 - 8.3e-23 80.8 0.0 3.7e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 PRP87546.1 - 8.4e-18 64.1 0.0 2e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_6 PF16661.5 PRP87546.1 - 4.2e-13 49.2 0.0 8.5e-12 44.9 0.0 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 PRP87546.1 - 9.9e-06 25.7 0.0 0.3 11.1 0.0 3.2 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PRP87546.1 - 0.002 17.7 0.1 0.031 13.8 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF3490 PF11995.8 PRP87548.1 - 0.085 12.7 0.4 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) Linker_histone PF00538.19 PRP87550.1 - 0.22 11.9 1.3 1.5 9.2 0.2 2.9 2 1 1 3 3 3 0 linker histone H1 and H5 family Mvb12 PF09452.10 PRP87550.1 - 0.67 10.4 5.1 0.2 12.1 0.8 2.4 2 1 1 3 3 3 0 ESCRT-I subunit Mvb12 rve PF00665.26 PRP87552.1 - 0.0071 16.5 0.1 0.1 12.8 0.0 2.5 2 1 1 3 3 3 1 Integrase core domain DUF722 PF05263.11 PRP87553.1 - 0.021 15.0 1.8 0.37 11.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF722) Ank_2 PF12796.7 PRP87556.1 - 0.0006 20.4 0.1 1.1 9.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Methyltransf_25 PF13649.6 PRP87556.1 - 0.0049 17.5 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ank_4 PF13637.6 PRP87556.1 - 0.0089 16.6 0.0 0.18 12.4 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Methyltransf_11 PF08241.12 PRP87556.1 - 0.013 16.2 0.0 0.029 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ank_3 PF13606.6 PRP87556.1 - 0.082 13.5 0.0 0.54 11.0 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeat Glyco_hydro_18 PF00704.28 PRP87557.1 - 1.2e-61 209.2 1.2 1.5e-61 208.8 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP87557.1 - 4.4e-19 68.7 73.3 3.2e-07 30.7 18.3 3.6 3 0 0 3 3 3 3 Chitin recognition protein DUF2039 PF10217.9 PRP87559.1 - 6.4e-28 96.9 14.8 1.3e-27 95.9 14.8 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) I_LWEQ PF01608.17 PRP87559.1 - 0.013 15.7 1.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 0 I/LWEQ domain Pheromone PF08015.11 PRP87559.1 - 0.089 13.9 0.1 0.27 12.3 0.1 1.9 1 0 0 1 1 1 0 Fungal mating-type pheromone zinc-ribbons_6 PF07191.12 PRP87559.1 - 0.35 10.9 16.6 7.9 6.6 16.9 2.4 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 PRP87559.1 - 0.53 10.4 13.7 9.9 6.3 11.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon Microcephalin PF12258.8 PRP87560.1 - 0.052 12.8 0.6 0.049 12.9 0.6 1.1 1 0 0 1 1 1 0 Microcephalin protein DEAD PF00270.29 PRP87561.1 - 2.9e-42 144.4 0.5 6.4e-42 143.3 0.5 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP87561.1 - 1e-24 87.0 23.3 1.3e-23 83.4 14.1 3.6 3 2 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 PRP87561.1 - 2.3e-11 44.0 0.0 2.3e-11 44.0 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 PRP87561.1 - 6.8e-06 24.7 17.7 6.8e-06 24.7 17.7 1.7 2 0 0 2 2 2 1 CDC45-like protein Nop14 PF04147.12 PRP87561.1 - 0.013 13.8 40.8 0.028 12.7 40.8 1.5 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 PRP87561.1 - 4 6.3 9.9 8.7 5.2 9.9 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ephrin_rec_like PF07699.13 PRP87562.1 - 5.9 6.7 11.1 1.9 8.3 2.9 2.7 2 0 0 2 2 2 0 Putative ephrin-receptor like Rap_GAP PF02145.15 PRP87563.1 - 3.9e-62 209.1 0.0 7.2e-62 208.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP RPEL PF02755.15 PRP87563.1 - 0.041 13.6 0.4 0.085 12.6 0.4 1.6 1 0 0 1 1 1 0 RPEL repeat Fmp27_SW PF10305.9 PRP87563.1 - 0.088 13.5 0.0 4.7 8.0 0.0 2.9 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain RNA_pol_Rpb8 PF03870.15 PRP87564.1 - 2.7e-51 173.4 0.1 3e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 PRP87564.1 - 0.00039 20.4 0.3 0.014 15.5 0.0 2.0 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G LSM PF01423.22 PRP87565.1 - 2.3e-16 59.2 1.1 2.7e-16 59.0 1.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 PRP87565.1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Hfq protein AAA_18 PF13238.6 PRP87566.1 - 9.3e-10 39.1 0.0 2.6e-09 37.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 PRP87566.1 - 9e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PRP87566.1 - 1.1e-05 25.1 0.1 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase dNK PF01712.19 PRP87566.1 - 0.0094 15.8 0.2 0.12 12.2 0.2 2.4 1 1 0 1 1 1 1 Deoxynucleoside kinase CoaE PF01121.20 PRP87566.1 - 0.044 13.4 1.1 0.98 9.1 0.0 2.6 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_33 PF13671.6 PRP87566.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PRP87566.1 - 0.051 13.9 1.9 1.1 9.5 0.2 3.0 2 1 1 3 3 3 0 AAA domain Gelsolin PF00626.22 PRP87567.1 - 2e-39 133.3 0.0 2.1e-13 50.0 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat CH PF00307.31 PRP87568.1 - 5.5e-15 55.5 0.0 8.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain BCDHK_Adom3 PF10436.9 PRP87569.1 - 0.025 14.4 0.1 0.061 13.2 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Zn_clus PF00172.18 PRP87569.1 - 9.7 6.4 8.2 0.22 11.7 0.9 2.0 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.20 PRP87570.1 - 1.9e-14 53.7 0.0 5.2e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP87570.1 - 3.6e-11 43.1 0.0 9.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP87570.1 - 9.7e-11 41.7 0.1 5.1e-10 39.4 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP87570.1 - 2.3e-10 40.7 0.2 1e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP87570.1 - 1.2e-08 35.1 0.1 7.3e-08 32.6 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain LRR_4 PF12799.7 PRP87570.1 - 1.7e-08 34.6 13.6 0.001 19.4 1.5 5.6 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) GST_C_2 PF13410.6 PRP87570.1 - 5.8e-08 32.6 0.0 1.9e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain LRR_9 PF14580.6 PRP87570.1 - 1.8e-07 30.9 1.5 6.3e-07 29.1 0.6 2.2 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PRP87570.1 - 2.3e-05 24.1 10.7 0.012 15.3 3.5 4.5 2 1 2 4 4 4 3 Leucine rich repeat GST_C_6 PF17171.4 PRP87570.1 - 0.013 15.2 0.0 0.037 13.8 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Guanylate_cyc PF00211.20 PRP87571.1 - 1.1e-94 315.2 0.5 3.2e-48 163.8 0.2 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 PRP87571.1 - 6.2e-06 25.8 1.5 0.081 12.3 0.0 2.4 2 0 0 2 2 2 2 Heme NO binding associated Phage_Gp23 PF10669.9 PRP87571.1 - 0.088 13.1 4.4 4.1 7.8 0.1 2.8 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Ndc1_Nup PF09531.10 PRP87571.1 - 1.7 7.2 8.2 0.21 10.2 0.9 2.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF872 PF05915.12 PRP87572.1 - 1.3e-11 44.7 0.0 1.3e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) DUF4013 PF13197.6 PRP87572.1 - 0.00031 20.6 0.2 0.0004 20.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) DUF3040 PF11239.8 PRP87572.1 - 0.00039 20.6 0.0 0.00045 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) Phage_holin_3_6 PF07332.11 PRP87572.1 - 0.0017 18.4 0.1 0.0022 18.0 0.1 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III DUF5362 PF17319.2 PRP87572.1 - 0.0018 18.1 0.4 0.0018 18.1 0.4 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5362) Claudin_2 PF13903.6 PRP87572.1 - 0.003 17.4 0.0 0.003 17.4 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF973 PF06157.11 PRP87572.1 - 0.0037 16.4 1.0 0.0041 16.2 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF973) DUF1418 PF07214.12 PRP87572.1 - 0.0047 16.8 0.5 0.0065 16.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1418) DUF2207 PF09972.9 PRP87572.1 - 0.0069 15.2 0.0 0.007 15.2 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 PRP87572.1 - 0.0085 15.8 0.3 0.012 15.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Neurensin PF14927.6 PRP87572.1 - 0.016 14.9 0.1 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 Neurensin DUF3671 PF12420.8 PRP87572.1 - 0.032 14.3 3.0 0.052 13.6 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF3098 PF11297.8 PRP87572.1 - 0.036 13.6 2.7 0.37 10.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) Tetraspanin PF00335.20 PRP87572.1 - 0.044 13.5 1.2 0.063 13.0 1.2 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4190 PF13828.6 PRP87572.1 - 0.061 13.1 3.7 0.11 12.3 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) DUF5337 PF17272.2 PRP87572.1 - 0.075 12.9 1.1 0.14 12.0 1.1 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5337) DUF3784 PF12650.7 PRP87572.1 - 0.086 13.0 4.2 0.16 12.2 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) DUF1129 PF06570.11 PRP87572.1 - 0.092 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3377 PF11857.8 PRP87572.1 - 0.093 12.7 3.4 0.082 12.8 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) DUF1461 PF07314.11 PRP87572.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) TssN PF17555.2 PRP87572.1 - 0.14 11.5 1.4 0.21 11.0 1.3 1.2 1 1 0 1 1 1 0 Type VI secretion system, TssN Oxidored_q2 PF00420.24 PRP87572.1 - 0.19 11.4 3.1 0.31 10.7 3.1 1.4 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Saf_2TM PF18303.1 PRP87572.1 - 0.4 10.3 4.1 0.17 11.5 0.3 1.9 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain YtpI PF14007.6 PRP87572.1 - 0.7 10.1 8.6 4.8 7.4 3.5 2.2 1 1 0 2 2 2 0 YtpI-like protein DUF1206 PF06724.11 PRP87572.1 - 2.6 8.2 8.0 36 4.5 8.0 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF3185 PF11381.8 PRP87572.1 - 6.9 6.8 14.3 73 3.5 13.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3185) DUF202 PF02656.15 PRP87572.1 - 7.5 7.1 6.5 2.2 8.8 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) UFD1 PF03152.14 PRP87573.1 - 8.1e-51 171.9 0.0 7e-50 168.9 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-TRAF PF02176.18 PRP87573.1 - 1.4e-06 28.9 20.7 0.00023 21.8 3.7 3.5 1 1 2 3 3 3 2 TRAF-type zinc finger RWD PF05773.22 PRP87573.1 - 0.00027 21.2 0.0 0.0014 18.9 0.0 2.2 2 0 0 2 2 1 1 RWD domain zf-C2H2 PF00096.26 PRP87573.1 - 0.0026 18.1 0.4 0.0026 18.1 0.4 4.5 5 0 0 5 5 5 1 Zinc finger, C2H2 type UQ_con PF00179.26 PRP87573.1 - 0.016 14.9 0.3 4.3 7.0 0.1 2.8 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme zf-C2H2_9 PF16293.5 PRP87573.1 - 0.02 14.8 1.3 0.056 13.3 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) CDC48_2 PF02933.17 PRP87573.1 - 0.02 14.7 0.1 0.053 13.3 0.1 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 zf-C2H2_4 PF13894.6 PRP87573.1 - 0.026 15.3 0.4 0.026 15.3 0.4 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger zf_C2H2_13 PF18508.1 PRP87573.1 - 0.056 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Zinc finger domain zf_UBZ PF18439.1 PRP87573.1 - 0.061 12.9 0.3 0.061 12.9 0.3 5.6 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger zf-MYND PF01753.18 PRP87573.1 - 0.32 11.1 6.9 1.2 9.3 0.0 3.2 2 1 0 2 2 2 0 MYND finger Sgf11 PF08209.11 PRP87573.1 - 0.38 10.3 7.6 3.7 7.2 0.1 3.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zf_C2H2_10 PF18414.1 PRP87573.1 - 0.43 10.2 2.7 1.9 8.1 0.3 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger zinc-ribbons_6 PF07191.12 PRP87573.1 - 3.8 7.6 20.1 0.067 13.2 1.4 3.2 3 0 0 3 3 3 0 zinc-ribbons MIOX PF05153.15 PRP87575.1 - 2.9e-113 377.5 7.4 3.5e-113 377.3 7.4 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 PRP87575.1 - 0.013 15.8 0.4 0.057 13.6 0.0 2.0 2 0 0 2 2 2 0 HD domain Joubert PF15392.6 PRP87575.1 - 0.043 13.5 0.2 0.063 13.0 0.2 1.2 1 0 0 1 1 1 0 Joubert syndrome-associated PPR_2 PF13041.6 PRP87576.1 - 1.6e-24 85.8 0.0 7.5e-09 35.7 0.0 5.7 5 1 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 PRP87576.1 - 2.1e-16 59.8 0.0 1.5e-05 25.0 0.0 4.8 4 1 1 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.20 PRP87576.1 - 1.2e-15 56.6 0.9 0.0086 16.3 0.0 6.1 6 0 0 6 6 6 4 PPR repeat PPR_1 PF12854.7 PRP87576.1 - 7.8e-10 38.3 0.6 0.0032 17.1 0.0 4.4 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 PRP87576.1 - 4.9e-07 29.3 0.0 0.0095 15.3 0.0 3.3 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP Exog_C PF18026.1 PRP87576.1 - 0.0001 22.3 0.9 15 5.7 0.0 4.6 5 0 0 5 5 5 1 Endo/exonuclease (EXOG) C-terminal domain ECSIT PF06239.11 PRP87576.1 - 0.0068 15.6 0.0 0.77 8.8 0.0 2.8 2 1 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway RasGEF PF00617.19 PRP87576.1 - 0.015 15.6 0.2 1.6 8.9 0.0 3.2 2 1 0 2 2 2 0 RasGEF domain TPR_14 PF13428.6 PRP87576.1 - 0.28 12.1 2.7 18 6.5 0.1 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat zinc_ribbon_2 PF13240.6 PRP87577.1 - 0.00047 19.8 2.3 0.00047 19.8 2.3 2.1 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 PRP87577.1 - 0.032 14.3 0.3 0.032 14.3 0.3 2.1 2 0 0 2 2 2 0 Double zinc ribbon NOB1_Zn_bind PF08772.11 PRP87577.1 - 0.36 11.0 3.8 3.9 7.7 0.1 3.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 PRP87577.1 - 3.5 7.2 7.0 0.58 9.7 2.0 2.3 2 1 0 2 2 2 0 zinc-ribbon domain CAF1A PF12253.8 PRP87578.1 - 1.3e-23 82.9 10.2 1.3e-23 82.9 10.2 4.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 PRP87578.1 - 2.3e-05 24.1 64.7 2.3e-05 24.1 64.7 3.4 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ZZ PF00569.17 PRP87579.1 - 1.4e-05 24.8 3.8 2.6e-05 24.0 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 PRP87579.1 - 0.0003 20.6 0.0 0.00059 19.7 0.0 1.5 1 0 0 1 1 1 1 PB1 domain AIM3 PF17096.5 PRP87579.1 - 0.087 13.8 0.4 0.087 13.8 0.4 1.9 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 DUF2642 PF10842.8 PRP87579.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) EMC3_TMCO1 PF01956.16 PRP87580.1 - 2.6e-27 95.6 0.0 3.2e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like XhlA PF10779.9 PRP87580.1 - 0.003 17.7 0.3 0.0061 16.7 0.3 1.6 1 0 0 1 1 1 1 Haemolysin XhlA LapA_dom PF06305.11 PRP87580.1 - 0.028 14.2 0.7 0.081 12.7 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TraF_2 PF13729.6 PRP87580.1 - 0.034 13.5 0.0 0.037 13.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein HlyD_2 PF12700.7 PRP87580.1 - 0.076 11.7 0.5 0.1 11.3 0.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein ZapD PF07072.11 PRP87580.1 - 0.09 12.5 0.2 0.12 12.1 0.2 1.1 1 0 0 1 1 1 0 Cell division protein MORN PF02493.20 PRP87581.1 - 9.9e-10 37.7 10.2 1.1e-05 25.0 1.8 3.9 4 0 0 4 4 4 3 MORN repeat LMBR1 PF04791.16 PRP87582.1 - 6e-31 107.9 22.4 1.1e-15 57.6 2.9 2.0 2 0 0 2 2 2 2 LMBR1-like membrane protein Tmemb_185A PF10269.9 PRP87583.1 - 8.9e-09 35.4 35.9 8.2e-05 22.4 14.0 3.2 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein F-box-like PF12937.7 PRP87583.1 - 2.9e-08 33.5 0.1 2.9e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP87583.1 - 7.5e-07 28.9 0.2 2.3e-06 27.3 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP87583.1 - 2.9e-05 23.9 0.0 5.1e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 F-box UCH PF00443.29 PRP87584.1 - 2.9e-56 190.8 0.7 2.9e-56 190.8 0.7 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP87584.1 - 4.3e-19 69.3 6.6 2.7e-16 60.1 6.6 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PRP87584.1 - 2.3e-16 59.8 11.4 2.3e-16 59.8 11.4 2.9 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 PRP87584.1 - 0.018 14.7 1.1 0.051 13.3 1.1 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger NqrM PF04400.13 PRP87584.1 - 0.052 13.3 2.6 0.15 11.8 2.6 1.7 1 0 0 1 1 1 0 (Na+)-NQR maturation NqrM TIG PF01833.24 PRP87586.1 - 2e-44 149.6 176.6 6.4e-10 39.0 5.1 19.3 19 2 2 21 21 21 12 IPT/TIG domain Pkinase_Tyr PF07714.17 PRP87586.1 - 6.7e-26 91.1 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87586.1 - 1.8e-21 76.7 0.0 3.8e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain W2 PF02020.18 PRP87586.1 - 1e-13 51.2 0.7 3.3e-13 49.6 0.5 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 PRP87586.1 - 7.2e-10 38.9 0.0 1.9e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyl transferase GPS PF01825.21 PRP87586.1 - 1.1e-09 38.6 8.8 3.2e-09 37.2 8.8 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Hexapep PF00132.24 PRP87586.1 - 0.00079 19.1 9.5 0.012 15.3 5.0 4.1 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) GLEYA PF10528.9 PRP87586.1 - 0.01 16.2 0.9 0.054 13.9 0.3 2.6 2 1 0 2 2 2 0 GLEYA domain NTP_transf_3 PF12804.7 PRP87586.1 - 0.084 13.2 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.6 PRP87586.1 - 0.27 11.0 8.5 0.046 13.5 2.4 3.1 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF4787 PF16029.5 PRP87587.1 - 1.3e-05 25.2 3.6 2.4e-05 24.3 3.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) Complex1_LYR PF05347.15 PRP87590.1 - 8.1e-10 38.6 0.3 2.1e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 PRP87590.1 - 0.0093 16.5 0.4 0.025 15.2 0.1 1.7 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 PRP87590.1 - 0.018 15.8 1.4 0.033 14.9 1.4 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Synaptobrevin PF00957.21 PRP87592.1 - 2.1e-30 104.4 3.5 3.1e-30 103.8 3.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PRP87592.1 - 2.3e-12 46.8 0.0 4.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2976 PF11190.8 PRP87592.1 - 0.022 14.5 0.5 3.9 7.3 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Ste5_C PF12194.8 PRP87592.1 - 0.032 14.2 1.0 0.049 13.6 1.0 1.2 1 0 0 1 1 1 0 Protein kinase Fus3-binding Fzo_mitofusin PF04799.13 PRP87592.1 - 0.071 12.7 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 fzo-like conserved region CwfJ_C_1 PF04677.15 PRP87593.1 - 4.5e-29 100.8 0.1 7e-29 100.2 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 PRP87593.1 - 5.5e-10 40.0 0.1 5.5e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 OmpH PF03938.14 PRP87593.1 - 0.92 9.8 5.8 17 5.8 0.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 PRP87594.1 - 3.7e-61 206.8 0.5 6.4e-61 206.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87594.1 - 2.5e-43 148.2 0.0 5.1e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP87594.1 - 0.0028 17.0 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP87594.1 - 0.091 11.5 0.0 0.091 11.5 0.0 2.7 2 1 0 2 2 2 0 Fungal protein kinase ABC_tran PF00005.27 PRP87594.1 - 2.2 8.8 4.4 4 8.0 0.2 2.4 2 0 0 2 2 2 0 ABC transporter LNS2 PF08235.13 PRP87595.1 - 4.6e-96 320.7 0.0 2.6e-95 318.2 0.0 2.1 2 1 1 3 3 3 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 PRP87595.1 - 9.7e-33 112.2 0.0 4.2e-32 110.1 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 PRP87595.1 - 4.3e-18 65.3 3.4 9.2e-18 64.3 0.0 2.8 3 0 0 3 3 3 1 Lipin/Ned1/Smp2 multi-domain protein middle domain PSII_Ycf12 PF05969.11 PRP87595.1 - 0.18 11.8 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 U1snRNP70_N PF12220.8 PRP87595.1 - 3.2 8.5 13.6 2.1 9.0 7.5 3.0 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Acylphosphatase PF00708.18 PRP87596.1 - 4.3e-18 65.5 0.3 8.8e-18 64.5 0.3 1.5 1 1 0 1 1 1 1 Acylphosphatase Pkinase PF00069.25 PRP87597.1 - 2.8e-65 220.3 0.0 5.9e-65 219.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87597.1 - 1.3e-25 90.1 0.0 3.3e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP87597.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Clat_adaptor_s PF01217.20 PRP87597.1 - 0.012 15.6 0.4 0.026 14.4 0.1 1.7 2 0 0 2 2 2 0 Clathrin adaptor complex small chain DUF667 PF05018.13 PRP87598.1 - 1.4e-48 165.1 0.0 1.7e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) ubiquitin PF00240.23 PRP87599.1 - 1.1e-34 118.0 0.9 1.4e-34 117.6 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 PRP87599.1 - 8.3e-30 102.4 9.5 1.3e-29 101.8 9.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 PRP87599.1 - 2.2e-16 59.4 1.0 2.9e-16 59.0 1.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP87599.1 - 7.8e-06 26.3 0.2 2.8e-05 24.5 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 PRP87599.1 - 0.0026 17.7 0.1 0.0034 17.3 0.1 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP87599.1 - 0.0033 17.7 0.1 0.0049 17.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP87599.1 - 0.0038 17.3 0.1 0.0093 16.1 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PRP87599.1 - 0.0081 16.7 0.1 0.0088 16.6 0.1 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 PRP87599.1 - 0.01 15.9 1.2 2.7 8.1 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 PRP87599.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Anoctamin PF04547.12 PRP87600.1 - 2.5e-113 379.3 8.3 3.3e-113 378.9 8.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 PRP87600.1 - 5.9e-09 36.0 0.4 3.8e-08 33.3 0.3 2.2 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin DnaJ_C PF01556.18 PRP87601.1 - 7.4e-35 120.2 0.3 1.1e-34 119.7 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain PDE4_UCR PF18100.1 PRP87601.1 - 0.082 13.6 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Phosphodiesterase 4 upstream conserved regions (UCR) Peptidase_M24 PF00557.24 PRP87603.1 - 1.1e-59 201.7 0.0 3e-59 200.2 0.0 1.8 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 PRP87603.1 - 1.1e-31 109.1 0.0 2.6e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TetR_C_31 PF17940.1 PRP87603.1 - 0.0064 16.7 3.2 0.017 15.3 3.2 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DDE_Tnp_1_assoc PF13808.6 PRP87603.1 - 0.012 15.6 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-associated ZapB PF06005.12 PRP87603.1 - 0.58 10.6 3.7 1.6 9.3 3.7 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Pet191_N PF10203.9 PRP87604.1 - 2.5e-14 53.3 6.8 2.8e-14 53.2 6.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CBM77 PF18283.1 PRP87604.1 - 0.049 14.0 0.0 0.052 13.9 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding module 77 NIP_1 PF08995.10 PRP87604.1 - 0.072 13.5 0.7 0.15 12.5 0.7 1.5 1 1 0 1 1 1 0 Necrosis inducing protein-1 Homeodomain PF00046.29 PRP87605.1 - 1.7e-05 24.6 0.0 6e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Homeodomain YdaS_antitoxin PF15943.5 PRP87605.1 - 0.0062 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeobox_KN PF05920.11 PRP87605.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain HTH_3 PF01381.22 PRP87605.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Peptidase_C1 PF00112.23 PRP87606.1 - 1.2e-48 166.1 4.5 2e-48 165.3 4.5 1.3 1 0 0 1 1 1 1 Papain family cysteine protease RhoGAP PF00620.27 PRP87606.1 - 1.2e-33 116.1 0.0 2.2e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 PRP87606.1 - 3.9e-14 52.4 8.6 5.6e-07 29.5 0.3 3.8 4 0 0 4 4 4 2 WW domain Peptidase_C1_2 PF03051.15 PRP87606.1 - 1.9e-07 30.2 0.4 0.00014 20.8 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 PRP87606.1 - 1.6e-06 28.4 1.8 3.5e-06 27.3 1.8 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PAN_4 PF14295.6 PRP87606.1 - 5.6e-06 26.2 3.1 1.5e-05 24.8 3.1 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PRP87606.1 - 8e-05 22.5 1.4 0.00023 21.0 1.4 1.7 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP87606.1 - 0.00056 20.0 0.8 0.0018 18.4 0.8 1.8 1 0 0 1 1 1 1 PAN-like domain PH PF00169.29 PRP87606.1 - 0.0011 19.5 0.4 0.0033 17.9 0.1 2.0 2 0 0 2 2 2 1 PH domain PAN_3 PF08277.12 PRP87606.1 - 0.26 11.1 4.1 0.31 10.9 2.3 2.1 2 0 0 2 2 2 0 PAN-like domain DUF3584 PF12128.8 PRP87607.1 - 0.37 8.2 32.4 0.72 7.3 32.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ATG27 PF09451.10 PRP87608.1 - 0.00026 20.9 0.2 0.0026 17.7 0.2 2.1 1 1 0 1 1 1 1 Autophagy-related protein 27 Zn_clus PF00172.18 PRP87609.1 - 5.1e-06 26.5 9.6 9.5e-06 25.6 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MeaB PF03308.16 PRP87610.1 - 3.8e-91 304.8 0.1 4.3e-91 304.6 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 PRP87610.1 - 9.5e-05 22.0 0.2 0.0012 18.5 0.2 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 PRP87610.1 - 0.00022 21.1 0.2 0.00068 19.5 0.0 1.9 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PRP87610.1 - 0.00025 21.6 0.2 0.012 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PRP87610.1 - 0.00064 19.5 0.6 0.0074 16.0 0.0 2.4 2 1 1 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 PRP87610.1 - 0.00092 19.3 0.1 0.005 16.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase CbiA PF01656.23 PRP87610.1 - 0.0015 18.5 0.0 0.0043 17.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 PRP87610.1 - 0.0016 18.7 0.1 0.0045 17.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP87610.1 - 0.0024 17.6 0.1 0.0043 16.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PRP87610.1 - 0.0029 17.4 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ParA PF10609.9 PRP87610.1 - 0.0036 16.8 0.1 0.042 13.3 0.0 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_29 PF13555.6 PRP87610.1 - 0.0039 16.9 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 PRP87610.1 - 0.0039 17.1 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 PRP87610.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ArsA_ATPase PF02374.15 PRP87610.1 - 0.021 14.0 0.6 0.04 13.1 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase AAA PF00004.29 PRP87610.1 - 0.046 14.1 0.1 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 PRP87610.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 PRP87610.1 - 0.055 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 PRP87610.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PRP87610.1 - 0.07 13.4 0.3 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 PRP87610.1 - 0.076 12.9 0.3 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 PRP87610.1 - 0.087 12.4 0.0 0.28 10.8 0.0 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 PRP87610.1 - 0.089 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_23 PF13476.6 PRP87610.1 - 0.14 12.7 0.1 0.33 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 PRP87610.1 - 0.18 11.0 0.3 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain EF-hand_7 PF13499.6 PRP87611.1 - 1e-19 70.8 8.6 7.2e-13 48.8 2.2 2.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP87611.1 - 6.6e-17 59.7 12.1 6.7e-07 28.4 0.4 4.5 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 PRP87611.1 - 3.8e-15 54.4 7.3 0.0012 18.7 0.5 4.8 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PRP87611.1 - 3e-14 51.8 10.6 9.4e-08 31.2 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PRP87611.1 - 6.9e-10 38.6 10.3 5.9e-06 26.0 3.1 4.2 2 1 2 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP87611.1 - 1e-06 29.1 0.5 0.0013 19.1 0.1 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PRP87611.1 - 0.002 18.0 3.1 0.4 10.6 0.3 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Lip_prot_lig_C PF10437.9 PRP87611.1 - 0.0058 16.6 2.4 0.02 14.9 0.8 2.4 2 1 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus DUF5580 PF17743.1 PRP87611.1 - 0.018 13.6 0.0 0.02 13.5 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5580) FGAR-AT_linker PF18072.1 PRP87611.1 - 0.044 14.3 1.5 15 6.2 0.3 3.3 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain Dockerin_1 PF00404.18 PRP87611.1 - 0.073 13.3 1.1 0.4 10.9 0.2 2.5 1 1 1 2 2 2 0 Dockerin type I domain SPO22 PF08631.10 PRP87611.1 - 0.081 12.4 0.0 0.097 12.1 0.0 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like DUF3349 PF11829.8 PRP87611.1 - 0.097 13.5 0.1 0.21 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) CEP44 PF15007.6 PRP87612.1 - 2.8e-35 121.2 0.3 5.5e-35 120.3 0.3 1.5 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Secretin_N_2 PF07655.13 PRP87613.1 - 1.9 9.1 10.7 3.6 8.2 8.4 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain PPR_2 PF13041.6 PRP87614.1 - 7.5e-36 122.1 11.7 1.4e-14 54.0 0.2 5.2 2 1 3 5 5 5 4 PPR repeat family PPR_1 PF12854.7 PRP87614.1 - 2.4e-25 87.9 7.4 1.3e-07 31.2 0.1 5.7 5 1 1 6 6 6 4 PPR repeat PPR PF01535.20 PRP87614.1 - 1.7e-24 84.3 7.9 1.1e-06 28.5 0.0 6.2 5 1 1 6 6 6 4 PPR repeat PPR_3 PF13812.6 PRP87614.1 - 1.7e-23 82.4 5.7 6.9e-13 48.5 0.6 5.1 3 2 3 6 6 6 3 Pentatricopeptide repeat domain Methyltransf_4 PF02390.17 PRP87614.1 - 8.3e-21 74.2 0.0 1e-19 70.7 0.0 2.6 1 1 0 1 1 1 1 Putative methyltransferase PPR_long PF17177.4 PRP87614.1 - 1.4e-14 54.0 1.2 3.1e-14 52.9 1.2 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 PRP87614.1 - 0.00088 19.1 0.0 0.0041 17.0 0.0 2.2 1 1 1 2 2 2 1 Mitochondrial ATPase expression BTAD PF03704.17 PRP87614.1 - 0.0024 18.3 0.2 1.4 9.3 0.0 2.8 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_14 PF13428.6 PRP87614.1 - 0.0097 16.7 0.2 21 6.3 0.0 4.3 3 2 2 5 5 5 0 Tetratricopeptide repeat RPM2 PF08579.11 PRP87614.1 - 0.045 14.1 2.8 1.2 9.6 0.0 3.4 1 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 PRP87614.1 - 0.057 13.5 0.0 28 5.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GST_C PF00043.25 PRP87615.1 - 6.3e-10 39.2 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PRP87615.1 - 6.2e-09 35.9 0.1 1.5e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP87615.1 - 1.3e-06 28.3 0.0 2.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NosD PF05048.13 PRP87615.1 - 0.00048 19.5 17.0 0.00048 19.5 17.0 2.3 2 1 0 2 2 2 1 Periplasmic copper-binding protein (NosD) GST_N PF02798.20 PRP87615.1 - 0.0027 18.0 0.0 0.0065 16.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP87615.1 - 0.01 16.3 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF1565 PF07602.11 PRP87615.1 - 0.011 15.1 2.2 2.3 7.5 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1565) FAD_binding_2 PF00890.24 PRP87616.1 - 1.9e-122 409.3 4.7 2.6e-122 408.9 4.7 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 PRP87616.1 - 4.2e-44 149.6 0.6 7.1e-44 148.9 0.6 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term RasGAP PF00616.19 PRP87616.1 - 8.8e-22 77.8 0.0 1.4e-13 51.0 0.0 2.4 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase SKG6 PF08693.10 PRP87616.1 - 0.0022 17.3 8.8 0.0044 16.4 8.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Pyr_redox_2 PF07992.14 PRP87616.1 - 0.0026 17.0 0.2 0.0058 15.9 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PRP87616.1 - 0.0051 16.1 0.2 0.0091 15.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 PRP87616.1 - 0.0076 15.4 0.6 0.19 10.8 1.3 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 PRP87616.1 - 0.0084 15.4 0.6 0.47 9.7 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Podoplanin PF05808.11 PRP87616.1 - 0.043 13.9 5.2 0.1 12.7 5.2 1.6 1 0 0 1 1 1 0 Podoplanin DAO PF01266.24 PRP87616.1 - 0.057 13.0 1.0 0.28 10.7 1.0 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Ank_4 PF13637.6 PRP87617.1 - 1.2e-06 28.9 0.0 0.15 12.7 0.0 5.0 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP87617.1 - 0.0011 19.3 0.1 4.5 7.7 0.0 4.7 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87617.1 - 0.0027 18.0 0.0 3.1 8.6 0.0 5.0 5 1 1 6 6 6 1 Ankyrin repeat F-box-like PF12937.7 PRP87617.1 - 0.0037 17.1 0.1 0.0077 16.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP87617.1 - 0.0038 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.7 PRP87617.1 - 0.017 15.7 0.0 3.9 8.1 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) DUF2521 PF10730.9 PRP87617.1 - 0.38 10.8 2.7 1.3 9.0 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) HOOK PF05622.12 PRP87618.1 - 1.8e-79 267.7 78.9 2.3e-79 267.4 78.9 1.0 1 0 0 1 1 1 1 HOOK protein CH PF00307.31 PRP87618.1 - 0.00052 20.2 0.8 0.0027 17.8 0.1 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain HALZ PF02183.18 PRP87618.1 - 0.0063 16.7 0.3 0.0063 16.7 0.3 9.3 10 1 2 12 12 12 2 Homeobox associated leucine zipper CAMSAP_CH PF11971.8 PRP87618.1 - 0.025 14.4 0.0 0.097 12.5 0.0 2.0 1 0 0 1 1 1 0 CAMSAP CH domain ATG16 PF08614.11 PRP87618.1 - 8.6 6.5 100.2 0.31 11.2 17.0 4.7 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Rap_GAP PF02145.15 PRP87619.1 - 5e-39 133.8 0.0 9.9e-39 132.8 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Pkinase_Tyr PF07714.17 PRP87620.1 - 4.8e-69 232.5 0.0 6.6e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87620.1 - 8e-53 179.5 0.0 1.2e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Beta_helix PF13229.6 PRP87620.1 - 3.7e-16 59.4 127.3 9.6e-05 22.3 23.3 7.8 1 1 5 6 6 6 5 Right handed beta helix region Pkinase_fungal PF17667.1 PRP87620.1 - 4.3e-05 22.5 0.0 6.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP87620.1 - 0.0093 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like EphA2_TM PF14575.6 PRP87620.1 - 0.12 13.3 0.3 0.45 11.4 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 PRP87620.1 - 0.24 10.7 0.0 0.5 9.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chlam_PMP PF02415.17 PRP87620.1 - 0.31 11.6 0.0 0.31 11.6 0.0 23.8 27 1 0 27 27 27 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pkinase_Tyr PF07714.17 PRP87621.1 - 3.3e-97 324.8 0.0 1.7e-48 165.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP87621.1 - 1.6e-70 237.5 0.0 2.2e-35 122.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Beta_helix PF13229.6 PRP87621.1 - 2.3e-31 108.8 137.7 2.5e-07 30.7 3.5 12.7 2 2 8 11 11 11 9 Right handed beta helix region Kdo PF06293.14 PRP87621.1 - 6.7e-09 35.4 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP87621.1 - 9.1e-05 21.4 0.2 0.093 11.5 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase PTP_tm PF18861.1 PRP87621.1 - 0.00065 19.7 2.6 0.36 10.8 0.2 2.5 2 0 0 2 2 2 2 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4957 PF16318.5 PRP87621.1 - 0.0043 17.0 38.7 1.6 8.7 2.0 9.4 4 2 3 7 7 7 3 Domain of unknown function (DUF4957) Syndecan PF01034.20 PRP87621.1 - 0.13 12.2 2.0 13 5.7 0.1 2.5 2 0 0 2 2 2 0 Syndecan domain NfeD PF01957.18 PRP87621.1 - 0.15 12.5 2.6 18 5.8 0.0 3.3 4 0 0 4 4 3 0 NfeD-like C-terminal, partner-binding EF-hand_1 PF00036.32 PRP87621.1 - 0.21 11.2 6.1 77 3.2 0.0 4.5 4 0 0 4 4 4 0 EF hand EPV_E5 PF08135.11 PRP87621.1 - 0.99 9.8 4.4 9.9 6.6 0.3 3.1 2 0 0 2 2 2 0 Major transforming protein E5 family HEV_ORF1 PF02444.16 PRP87621.1 - 3.2 8.4 5.1 14 6.3 0.5 2.7 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) SAC3_GANP PF03399.16 PRP87622.1 - 4.4e-11 42.7 1.2 1.5e-06 27.8 0.1 2.7 2 1 0 2 2 2 2 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 PRP87622.1 - 5.2e-05 23.3 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family RRM_1 PF00076.22 PRP87624.1 - 1.1e-14 53.9 0.0 1.7e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PRP87624.1 - 9.1e-09 35.0 2.9 1.5e-08 34.3 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PRP87624.1 - 5.5e-05 22.9 1.0 8.1e-05 22.4 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 PRP87624.1 - 0.011 15.4 1.0 0.023 14.4 1.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Nup35_RRM_2 PF14605.6 PRP87624.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCHC_4 PF14392.6 PRP87624.1 - 0.071 12.9 0.6 0.11 12.2 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 PRP87624.1 - 0.072 13.1 0.1 0.072 13.1 0.1 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 PRP87624.1 - 0.19 11.6 1.4 0.41 10.5 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle HAUS4 PF14735.6 PRP87625.1 - 3.4e-36 125.1 11.0 3.4e-36 125.1 11.0 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 TBCC_N PF16752.5 PRP87625.1 - 0.033 14.6 1.5 0.033 14.6 1.5 3.1 3 1 1 4 4 4 0 Tubulin-specific chaperone C N-terminal domain Globin PF00042.22 PRP87625.1 - 0.078 13.5 0.0 0.24 12.0 0.0 1.9 1 0 0 1 1 1 0 Globin PLU-1 PF08429.11 PRP87625.1 - 0.092 11.9 11.0 0.13 11.4 1.0 2.8 3 0 0 3 3 3 0 PLU-1-like protein IL11 PF07400.11 PRP87625.1 - 0.17 11.5 4.2 0.084 12.5 1.3 2.0 2 0 0 2 2 2 0 Interleukin 11 DUF1840 PF08895.11 PRP87625.1 - 2.3 8.6 4.7 1.6 9.1 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) HalX PF08663.10 PRP87625.1 - 4.6 7.6 9.3 1.1 9.7 0.4 3.7 4 0 0 4 4 4 0 HalX domain DWNN PF08783.11 PRP87626.1 - 6.1e-10 39.2 0.0 1.2e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC PF00098.23 PRP87626.1 - 0.00011 22.1 6.6 0.00011 22.1 6.6 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_3 PF13920.6 PRP87626.1 - 0.00027 20.7 8.5 0.00027 20.7 8.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_2 PF13696.6 PRP87626.1 - 0.00078 19.2 7.2 0.00078 19.2 7.2 2.5 3 0 0 3 3 3 1 Zinc knuckle zf-C3HC4_4 PF15227.6 PRP87626.1 - 0.0017 18.5 9.8 0.0017 18.5 9.8 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 PRP87626.1 - 0.002 18.2 0.0 0.0056 16.8 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-CCHC_3 PF13917.6 PRP87626.1 - 0.0029 17.5 2.8 0.0083 16.1 2.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-RING_5 PF14634.6 PRP87626.1 - 0.012 15.5 10.0 0.012 15.5 10.0 2.4 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 PRP87626.1 - 0.015 15.3 5.1 0.036 14.1 5.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger CpXC PF14353.6 PRP87626.1 - 0.026 14.6 12.4 1 9.4 9.0 2.9 2 1 0 2 2 2 0 CpXC protein VIR_N PF15912.5 PRP87626.1 - 0.1 12.2 7.5 0.08 12.5 6.0 1.6 1 1 0 1 1 1 0 Virilizer, N-terminal zf-C3HC4 PF00097.25 PRP87626.1 - 1 9.3 14.8 0.055 13.4 8.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PRP87626.1 - 3.9 7.4 20.9 0.032 14.1 9.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP87626.1 - 6.7 6.7 17.7 0.054 13.4 9.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 SPRY PF00622.28 PRP87627.1 - 1.9e-19 69.9 4.7 1.3e-05 25.3 0.1 3.5 3 0 0 3 3 3 3 SPRY domain DUF1736 PF08409.11 PRP87627.1 - 0.15 12.1 0.9 4.2 7.4 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1736) adh_short_C2 PF13561.6 PRP87628.1 - 1.9e-54 184.7 1.6 2.3e-54 184.4 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP87628.1 - 6e-52 175.9 4.2 7e-52 175.7 4.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP87628.1 - 2.1e-14 53.8 1.6 3.2e-14 53.2 1.6 1.2 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 PRP87628.1 - 3.1e-05 23.9 2.8 0.0015 18.6 0.4 2.2 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 PRP87628.1 - 0.00084 19.3 1.6 0.0016 18.4 1.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 PRP87628.1 - 0.0009 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 PRP87628.1 - 0.0036 16.8 0.4 0.0047 16.4 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 PRP87628.1 - 0.014 15.0 0.7 0.04 13.6 0.3 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 PRP87628.1 - 0.031 14.8 2.1 0.032 14.8 0.6 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 PRP87628.1 - 0.11 12.5 2.7 0.11 12.5 0.6 2.1 2 1 1 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 PRP87628.1 - 0.39 10.8 2.6 0.87 9.6 1.2 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 PRP87629.1 - 0.023 15.4 0.0 0.032 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LRR_4 PF12799.7 PRP87630.1 - 9.4e-13 48.1 25.0 6.7e-07 29.5 0.4 4.8 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP87630.1 - 1.9e-12 46.7 17.2 1.7e-08 34.1 5.6 4.3 1 1 4 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 PRP87630.1 - 3e-10 39.2 25.8 0.037 14.6 0.4 7.7 7 1 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.6 PRP87630.1 - 1.2e-05 25.0 26.2 0.74 10.0 1.0 6.6 7 0 0 7 7 7 4 Leucine Rich repeat LRRNT_2 PF08263.12 PRP87630.1 - 0.0011 19.2 0.6 0.0021 18.3 0.6 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DUF2436 PF10365.9 PRP87630.1 - 0.066 13.0 0.0 0.31 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2436) DUF4501 PF14946.6 PRP87630.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) TFCD_C PF12612.8 PRP87633.1 - 8.8e-40 136.6 0.1 4.3e-38 131.1 0.0 3.3 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 PRP87633.1 - 0.00014 22.2 3.4 4.9 7.6 0.0 6.2 8 1 0 8 8 8 1 HEAT repeats HEAT PF02985.22 PRP87633.1 - 0.00043 20.3 15.9 0.092 13.1 0.0 8.3 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.6 PRP87633.1 - 0.0024 18.3 10.4 0.94 10.1 0.0 7.0 7 1 1 8 8 8 1 HEAT-like repeat IFRD PF05004.13 PRP87633.1 - 0.026 13.6 0.1 5.8 5.9 0.1 3.4 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 PRP87633.1 - 0.072 13.1 0.1 1.2 9.2 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 MMM1 PF10296.9 PRP87634.1 - 2.3e-06 26.9 0.0 2.5e-05 23.5 0.0 1.9 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 EamA PF00892.20 PRP87635.1 - 2.7e-08 34.1 9.7 5.3e-08 33.1 9.7 1.6 1 1 0 1 1 1 1 EamA-like transporter family OPT PF03169.15 PRP87635.1 - 0.0003 19.6 0.6 0.00038 19.2 0.6 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sugar_transport PF06800.12 PRP87635.1 - 0.0026 17.2 0.7 0.0036 16.7 0.7 1.3 1 0 0 1 1 1 1 Sugar transport protein TMEM234 PF10639.9 PRP87635.1 - 0.0099 15.9 1.7 0.013 15.5 1.7 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF3488 PF11992.8 PRP87635.1 - 0.016 14.2 0.9 0.019 13.9 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Multi_Drug_Res PF00893.19 PRP87635.1 - 0.049 14.3 4.1 0.083 13.6 1.4 2.2 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF1118 PF06549.12 PRP87635.1 - 0.077 13.3 0.1 0.12 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) Pkinase PF00069.25 PRP87636.1 - 1.9e-58 197.9 0.0 2.9e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87636.1 - 1.2e-39 136.2 0.1 1.9e-39 135.6 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP87636.1 - 4.3e-05 22.5 0.2 4.3e-05 22.5 0.2 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP87636.1 - 0.002 17.5 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP87636.1 - 0.007 15.4 0.5 0.014 14.4 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 PRP87636.1 - 0.0073 15.4 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 PRP87636.1 - 0.038 13.9 0.0 0.13 12.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP87636.1 - 0.052 13.1 0.1 0.052 13.1 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase PIN_2 PF10130.9 PRP87636.1 - 0.065 13.5 0.2 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 PIN domain DSPc PF00782.20 PRP87637.1 - 2e-19 69.7 0.0 3.2e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP87637.1 - 0.00039 20.1 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 PRP87637.1 - 0.0045 17.3 0.0 0.0087 16.4 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 PRP87637.1 - 0.011 15.9 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 PRP87637.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 PRP87637.1 - 0.03 14.0 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Rhodanese PF00581.20 PRP87637.1 - 0.052 14.1 0.0 0.084 13.4 0.0 1.3 1 0 0 1 1 1 0 Rhodanese-like domain WD40 PF00400.32 PRP87638.1 - 1.7e-16 60.3 10.7 2.6e-07 31.2 0.4 4.6 5 0 0 5 5 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP87638.1 - 4.2e-05 23.8 0.8 0.2 12.0 0.2 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP87638.1 - 0.00023 20.6 0.2 0.04 13.2 0.1 2.3 1 1 1 2 2 2 2 WD40-like domain zf-RING_2 PF13639.6 PRP87638.1 - 0.00035 20.8 4.7 0.00035 20.8 4.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 PRP87638.1 - 0.00049 20.0 3.4 0.00049 20.0 3.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Nup160 PF11715.8 PRP87638.1 - 0.0023 16.6 0.3 0.019 13.6 0.2 2.0 1 1 0 2 2 2 1 Nucleoporin Nup120/160 PHD PF00628.29 PRP87638.1 - 0.0045 16.9 3.2 0.0045 16.9 3.2 2.9 3 0 0 3 3 2 1 PHD-finger zf-B_box PF00643.24 PRP87638.1 - 0.024 14.8 3.5 0.024 14.8 3.5 3.3 3 0 0 3 3 3 0 B-box zinc finger zf-RING_11 PF17123.5 PRP87638.1 - 0.048 13.4 1.5 0.16 11.7 1.5 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 PRP87638.1 - 0.7 10.0 8.3 0.12 12.4 3.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger PHD_4 PF16866.5 PRP87638.1 - 2.5 8.3 8.7 30 4.8 8.7 2.9 1 1 0 1 1 1 0 PHD-finger SRR1 PF07985.12 PRP87639.1 - 1.1e-15 57.4 0.0 1.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 Adaptin_N PF01602.20 PRP87640.1 - 7.1e-137 457.1 10.9 1.1e-136 456.5 10.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PRP87640.1 - 8.1e-20 71.5 9.4 1.9e-17 63.8 0.1 3.9 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 PRP87640.1 - 6.9e-14 52.3 0.0 1.8e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 PRP87640.1 - 1.3e-07 31.9 1.7 0.022 15.1 0.1 4.1 2 1 2 4 4 4 4 HEAT repeats SPO22 PF08631.10 PRP87640.1 - 5.4e-06 26.1 3.7 0.0019 17.7 0.2 2.5 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like Svf1_C PF17187.4 PRP87640.1 - 0.00012 21.9 0.9 0.0032 17.3 0.2 2.6 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain MOR2-PAG1_C PF14225.6 PRP87640.1 - 0.0017 18.3 2.5 0.003 17.5 0.1 2.4 2 0 0 2 2 2 1 Cell morphogenesis C-terminal HEAT_EZ PF13513.6 PRP87640.1 - 0.0024 18.4 0.5 4.2 8.0 0.1 4.0 3 0 0 3 3 3 1 HEAT-like repeat DRIM PF07539.12 PRP87640.1 - 0.0029 16.0 0.3 0.0029 16.0 0.3 2.2 2 1 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.22 PRP87640.1 - 0.0036 17.4 2.8 0.58 10.6 0.0 4.7 5 1 1 6 6 6 1 HEAT repeat eIF3_subunit PF08597.10 PRP87640.1 - 0.016 15.1 18.8 0.016 15.1 11.4 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Sec7_N PF12783.7 PRP87640.1 - 0.41 10.5 2.3 0.58 10.1 0.4 2.1 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Peptidase_S10 PF00450.22 PRP87642.1 - 4.9e-114 382.0 1.9 7.2e-113 378.2 1.9 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Homeodomain PF00046.29 PRP87644.1 - 7.7e-08 32.1 3.0 0.0056 16.5 0.8 2.2 1 1 1 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 PRP87644.1 - 0.001 19.0 0.5 0.28 11.1 0.2 2.4 2 0 0 2 2 2 2 Homeobox KN domain HTH_26 PF13443.6 PRP87644.1 - 0.02 15.3 0.2 3.2 8.3 0.1 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain YdaS_antitoxin PF15943.5 PRP87644.1 - 0.066 13.1 0.1 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_3 PF01381.22 PRP87644.1 - 0.072 13.2 0.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix Phage_AlpA PF05930.12 PRP87644.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Ceramidase PF05875.12 PRP87645.1 - 5.3e-60 203.1 16.3 7.6e-60 202.6 16.3 1.2 1 0 0 1 1 1 1 Ceramidase Nucleos_tra2_N PF01773.20 PRP87645.1 - 0.0012 19.3 0.6 0.0038 17.8 0.6 1.8 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus Leader_Trp PF08255.11 PRP87645.1 - 0.09 12.8 2.6 0.58 10.3 2.6 2.4 1 0 0 1 1 1 0 Trp-operon Leader Peptide PepSY_TM PF03929.16 PRP87645.1 - 1.5 8.4 6.8 0.15 11.7 1.4 1.9 2 0 0 2 2 2 0 PepSY-associated TM region DUF2263 PF10021.9 PRP87647.1 - 6.8e-27 94.6 0.0 1.8e-26 93.3 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 PRP87647.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Macro domain FAM184 PF15665.5 PRP87648.1 - 0.34 10.7 24.4 0.53 10.0 23.7 1.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 PRP87648.1 - 1.3 8.5 13.2 1.6 8.2 13.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mut7-C PF01927.16 PRP87648.1 - 1.5 9.0 8.1 2.9 8.0 8.1 1.6 1 1 0 1 1 1 0 Mut7-C RNAse domain T3SS_basalb_I PF17001.5 PRP87648.1 - 1.5 9.4 11.4 0.49 11.0 5.4 2.3 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF4407 PF14362.6 PRP87648.1 - 1.9 7.7 15.9 3.3 7.0 15.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS-augmin3 PF14932.6 PRP87648.1 - 3.9 7.0 17.7 4.5 6.8 16.3 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 CortBP2 PF09727.9 PRP87648.1 - 6.3 6.7 28.2 1.6 8.6 12.6 2.5 1 1 1 2 2 2 0 Cortactin-binding protein-2 ADIP PF11559.8 PRP87648.1 - 6.4 6.8 29.4 0.48 10.5 21.4 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding LMBR1 PF04791.16 PRP87648.1 - 9.1 5.1 10.9 10 4.9 10.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IFP_35_N PF07334.13 PRP87648.1 - 9.9 6.3 15.5 4.5 7.4 0.8 3.2 3 1 1 4 4 4 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus YfhO PF09586.10 PRP87649.1 - 5.8 5.0 5.0 7.1 4.7 2.6 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DEAD PF00270.29 PRP87650.1 - 7.9e-44 149.5 0.0 4.2e-42 143.9 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP87650.1 - 2.1e-26 92.4 0.0 5.6e-26 91.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP87650.1 - 9.6e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PRP87650.1 - 0.00028 20.3 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.23 PRP87650.1 - 0.0031 16.3 0.0 0.0043 15.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 PRP87650.1 - 0.1 12.9 0.0 5.7 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF727 PF05303.12 PRP87651.1 - 2.4e-05 24.3 0.8 3.7e-05 23.7 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF727) Transglut_core PF01841.19 PRP87653.1 - 1.3e-10 41.7 0.0 2.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily EF-hand_4 PF12763.7 PRP87653.1 - 4.8e-10 39.3 0.0 9.1e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Ras PF00071.22 PRP87654.1 - 3.3e-55 186.1 0.0 9.5e-55 184.6 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP87654.1 - 9.7e-20 71.0 0.0 1.9e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Homeobox_KN PF05920.11 PRP87654.1 - 1.4e-16 60.1 0.6 4.4e-16 58.5 0.6 2.0 1 0 0 1 1 1 1 Homeobox KN domain DNA_primase_S PF01896.19 PRP87654.1 - 6.8e-10 39.3 0.0 2.3e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 DNA primase small subunit Arf PF00025.21 PRP87654.1 - 9.8e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Homeodomain PF00046.29 PRP87654.1 - 0.00021 21.1 0.2 0.00021 21.1 0.2 2.2 2 0 0 2 2 2 1 Homeodomain FeoB_N PF02421.18 PRP87654.1 - 0.0011 18.5 0.0 0.0023 17.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP87654.1 - 0.0052 16.7 0.0 0.78 9.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PRP87654.1 - 0.013 15.1 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP87654.1 - 0.17 12.0 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Tektin PF03148.14 PRP87654.1 - 1.5 7.5 5.0 12 4.5 0.2 2.2 2 0 0 2 2 2 0 Tektin family MSP1a PF11670.8 PRP87655.1 - 0.0022 17.4 2.3 0.0036 16.6 2.3 1.3 1 0 0 1 1 1 1 Major surface protein 1a (MSP1a) TcpE PF12648.7 PRP87655.1 - 0.64 10.6 6.3 4.4 7.9 0.2 2.7 2 0 0 2 2 2 0 TcpE family DUF4064 PF13273.6 PRP87655.1 - 6.2 7.2 15.5 11 6.4 3.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DNA_pol_B_thumb PF14791.6 PRP87656.1 - 7.2e-22 77.3 0.1 7.2e-22 77.3 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 PRP87656.1 - 5.5e-16 58.7 0.4 1.2e-15 57.6 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 PRP87656.1 - 2.1e-12 47.3 0.1 3.2e-08 33.7 0.0 2.6 1 1 1 2 2 2 2 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 PRP87656.1 - 5.2e-12 45.4 0.1 7e-11 41.8 0.1 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda zf-GRF PF06839.12 PRP87656.1 - 8.2e-12 45.0 4.3 1.7e-11 44.0 4.3 1.6 1 0 0 1 1 1 1 GRF zinc finger BRCT_2 PF16589.5 PRP87656.1 - 6.5e-06 26.5 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 PRP87656.1 - 0.011 16.4 0.2 0.024 15.2 0.2 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3824 PF12868.7 PRP87656.1 - 0.015 16.0 8.5 0.038 14.6 8.5 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Resolvase PF00239.21 PRP87656.1 - 0.4 10.8 2.2 11 6.1 1.1 2.4 2 0 0 2 2 2 0 Resolvase, N terminal domain DUF1682 PF07946.14 PRP87656.1 - 0.5 9.5 7.3 0.85 8.8 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Dicty_CTDC PF00526.18 PRP87657.1 - 0.00018 21.3 7.9 0.00018 21.3 7.9 14.9 16 2 0 16 16 16 6 Dictyostelium (slime mold) repeat Bacteriocin_IIc PF10439.9 PRP87657.1 - 5.5 7.2 12.6 13 6.0 12.6 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide PA14 PF07691.12 PRP87658.1 - 3.5e-09 36.6 0.0 6.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 PRP87658.1 - 0.00028 20.7 7.9 0.00028 20.7 7.9 13.6 14 1 0 14 14 14 6 Dictyostelium (slime mold) repeat Bacteriocin_IIc PF10439.9 PRP87658.1 - 8.9 6.5 12.6 20 5.4 12.6 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DNA_pol_B_thumb PF14791.6 PRP87659.1 - 3.7e-22 78.3 0.1 1e-21 76.9 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 PRP87659.1 - 7e-16 58.4 0.4 1.5e-15 57.3 0.4 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.6 PRP87659.1 - 3.2e-12 46.7 0.1 4.1e-08 33.4 0.0 2.7 1 1 1 2 2 2 2 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 PRP87659.1 - 7.9e-12 44.8 0.1 8.7e-11 41.5 0.1 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda zf-GRF PF06839.12 PRP87659.1 - 9.7e-12 44.8 4.3 2.2e-11 43.7 4.3 1.6 1 0 0 1 1 1 1 GRF zinc finger BRCT_2 PF16589.5 PRP87659.1 - 7.9e-06 26.2 0.0 1.8e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain HHH_5 PF14520.6 PRP87659.1 - 0.014 16.0 0.2 0.03 14.9 0.2 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3824 PF12868.7 PRP87659.1 - 0.02 15.6 8.5 0.049 14.3 8.5 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF1682 PF07946.14 PRP87659.1 - 0.6 9.3 7.3 1.1 8.4 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ras PF00071.22 PRP87661.1 - 3e-55 186.2 0.0 8.8e-55 184.7 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP87661.1 - 9.2e-20 71.1 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Homeobox_KN PF05920.11 PRP87661.1 - 1.2e-16 60.3 0.6 4.1e-16 58.6 0.6 2.0 1 0 0 1 1 1 1 Homeobox KN domain Arf PF00025.21 PRP87661.1 - 9.3e-08 31.7 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Homeodomain PF00046.29 PRP87661.1 - 0.0002 21.2 0.2 0.0002 21.2 0.2 2.2 2 0 0 2 2 2 1 Homeodomain FeoB_N PF02421.18 PRP87661.1 - 0.001 18.6 0.0 0.0021 17.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP87661.1 - 0.0051 16.7 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PRP87661.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Transglut_core PF01841.19 PRP87662.1 - 1.3e-10 41.7 0.0 2.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily EF-hand_4 PF12763.7 PRP87662.1 - 4.8e-10 39.3 0.0 9.1e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF727 PF05303.12 PRP87664.1 - 2.4e-05 24.3 0.8 3.7e-05 23.7 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF727) DEAD PF00270.29 PRP87665.1 - 7.9e-44 149.5 0.0 4.2e-42 143.9 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP87665.1 - 2.1e-26 92.4 0.0 5.6e-26 91.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP87665.1 - 9.6e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PRP87665.1 - 0.00028 20.3 0.0 0.00067 19.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.23 PRP87665.1 - 0.0031 16.3 0.0 0.0043 15.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 PRP87665.1 - 0.1 12.9 0.0 5.7 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain YfhO PF09586.10 PRP87666.1 - 5.8 5.0 5.0 7.1 4.7 2.6 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Pkinase_Tyr PF07714.17 PRP87667.1 - 6.7e-52 176.3 0.0 1.1e-51 175.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87667.1 - 2.6e-47 161.4 0.0 4.8e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 PRP87667.1 - 1.3e-15 57.7 0.1 4.3e-09 36.8 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) DUF4730 PF15873.5 PRP87667.1 - 3.5e-12 46.4 0.6 1.4e-11 44.5 0.6 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4730) Ank_4 PF13637.6 PRP87667.1 - 3.6e-11 43.3 0.0 0.01 16.4 0.0 5.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 PRP87667.1 - 2.5e-10 40.7 0.0 6.5e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 PRP87667.1 - 3.9e-09 36.6 0.1 8.7e-06 25.9 0.0 4.8 3 2 1 5 5 5 2 Ankyrin repeats (many copies) SAM_2 PF07647.17 PRP87667.1 - 8.5e-09 35.4 0.0 2.9e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank PF00023.30 PRP87667.1 - 2.4e-08 34.1 0.5 0.0013 19.1 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 PRP87667.1 - 3.2e-07 30.1 3.3 0.046 14.3 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat DUF4579 PF15158.6 PRP87668.1 - 0.096 12.4 1.6 0.2 11.4 0.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4579) Transcrip_reg PF01709.20 PRP87669.1 - 6.9e-66 222.1 0.0 7.9e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Glyco_transf_22 PF03901.17 PRP87670.1 - 1e-26 94.1 34.1 1e-26 94.1 34.1 1.8 2 0 0 2 2 2 1 Alg9-like mannosyltransferase family Pur_ac_phosph_N PF16656.5 PRP87670.1 - 1.3e-22 80.2 0.3 3.6e-22 78.7 0.3 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 PRP87670.1 - 2.6e-21 77.1 0.6 4.8e-21 76.2 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PRP87670.1 - 2e-11 44.5 0.0 4.7e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD_N PF16655.5 PRP87670.1 - 0.0023 18.4 0.0 0.0061 17.1 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain L31 PF09784.9 PRP87670.1 - 0.086 13.3 1.3 0.16 12.4 1.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Peptidase_C1 PF00112.23 PRP87672.1 - 2.8e-46 158.3 6.4 8.1e-46 156.8 6.4 1.8 1 0 0 1 1 1 1 Papain family cysteine protease WSC PF01822.19 PRP87672.1 - 2.5e-17 62.8 43.9 1e-14 54.5 11.9 3.9 3 0 0 3 3 3 2 WSC domain CAP PF00188.26 PRP87672.1 - 4e-16 60.0 0.5 4e-16 60.0 0.5 3.3 3 0 0 3 3 3 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.15 PRP87672.1 - 0.0013 17.6 2.7 0.091 11.5 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family 5_nucleotid PF05761.14 PRP87673.1 - 1.2e-155 518.9 1.2 1.4e-155 518.7 1.2 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 PRP87673.1 - 0.00034 20.7 0.1 1.7 8.7 0.0 3.3 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase GST_C_3 PF14497.6 PRP87673.1 - 0.0094 16.1 0.1 0.034 14.4 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hydrolase PF00702.26 PRP87673.1 - 0.053 13.8 0.0 1.7 8.9 0.0 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Cyclin PF08613.11 PRP87674.1 - 4.9e-08 33.5 0.8 1.5e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin Homeobox_KN PF05920.11 PRP87675.1 - 7.7e-18 64.1 0.1 1.5e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PRP87675.1 - 6.7e-06 25.9 0.0 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Homeodomain RasGEF PF00617.19 PRP87676.1 - 5.4e-55 186.3 2.1 1.3e-54 185.1 2.1 1.7 1 0 0 1 1 1 1 RasGEF domain Ras PF00071.22 PRP87676.1 - 6.3e-38 129.9 0.1 1.6e-37 128.6 0.1 1.7 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP87676.1 - 2.3e-18 66.5 0.0 6.2e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RasGEF_N PF00618.20 PRP87676.1 - 2.6e-12 46.9 4.4 2.8e-12 46.8 0.2 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif Arf PF00025.21 PRP87676.1 - 4.1e-09 36.1 0.0 7.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DEP PF00610.21 PRP87676.1 - 0.002 18.2 0.1 0.0051 16.8 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MMR_HSR1 PF01926.23 PRP87676.1 - 0.07 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 PRP87676.1 - 0.26 11.0 1.9 4.2 7.1 1.2 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RAI1 PF08652.11 PRP87677.1 - 1.2e-19 70.3 0.0 2.3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Herpes_US9 PF06072.11 PRP87677.1 - 0.076 12.9 0.1 0.076 12.9 0.1 1.7 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Methyltransf_16 PF10294.9 PRP87678.1 - 3.5e-23 82.2 0.0 4.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 PRP87678.1 - 0.0019 18.0 0.0 0.0048 16.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP87678.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP87678.1 - 0.0026 17.3 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP87678.1 - 0.003 18.2 0.0 0.0051 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PRP87678.1 - 0.0044 16.5 0.0 0.0062 16.0 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 PRP87678.1 - 0.016 16.0 0.0 0.035 14.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain LIN52 PF10044.9 PRP87679.1 - 0.0014 19.3 0.0 0.0024 18.5 0.0 1.4 1 0 0 1 1 1 1 Retinal tissue protein LRR_6 PF13516.6 PRP87680.1 - 1.3e-09 37.3 1.1 0.00027 20.7 0.2 4.5 4 0 0 4 4 4 2 Leucine Rich repeat zf-MYND PF01753.18 PRP87680.1 - 4.9e-06 26.5 12.8 1.1e-05 25.4 12.8 1.6 1 0 0 1 1 1 1 MYND finger LRR_1 PF00560.33 PRP87680.1 - 0.0065 16.8 2.5 12 6.9 0.0 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat ARF7EP_C PF14949.6 PRP87680.1 - 0.019 15.6 10.3 0.042 14.5 10.3 1.5 1 0 0 1 1 1 0 ARF7 effector protein C-terminus SIR2 PF02146.17 PRP87681.1 - 1.8e-61 207.2 0.0 2.7e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF3381 PF11861.8 PRP87681.1 - 0.017 15.0 0.1 0.017 15.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) zf-3CxxC_2 PF17180.4 PRP87681.1 - 0.073 13.8 0.1 0.2 12.4 0.1 1.7 1 0 0 1 1 1 0 Zinc-binding domain TPP_enzyme_M PF00205.22 PRP87681.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain zf-trcl PF13451.6 PRP87681.1 - 8.3 6.4 6.8 1.2e+02 2.7 6.8 2.3 1 1 0 1 1 1 0 Probable zinc-ribbon domain BRCA-2_OB1 PF09103.10 PRP87682.1 - 3.1e-33 114.3 0.0 7.4e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 PRP87682.1 - 4.4e-23 81.9 0.8 3e-20 72.7 0.0 2.4 1 1 1 2 2 2 2 BRCA2, helical BRCA2 PF00634.18 PRP87682.1 - 2.8e-11 42.9 50.5 0.0087 15.7 0.1 12.3 11 3 0 11 11 11 10 BRCA2 repeat BRCA-2_OB3 PF09104.10 PRP87682.1 - 2e-05 24.3 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF3458 PF11940.8 PRP87682.1 - 0.13 12.7 0.4 17 5.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3458) Ig-like fold COMM_domain PF07258.14 PRP87683.1 - 9.6e-19 67.3 0.7 9.6e-19 67.3 0.7 1.8 2 0 0 2 2 2 1 COMM domain Cyclin_N PF00134.23 PRP87684.1 - 1.1e-45 154.5 0.5 1.7e-45 153.8 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP87684.1 - 1.4e-21 76.8 0.4 3.4e-21 75.6 0.5 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Pkinase PF00069.25 PRP87685.1 - 5e-33 114.6 2.2 5.2e-33 114.5 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain DEAD PF00270.29 PRP87685.1 - 1.6e-19 70.3 0.0 1.6e-19 70.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pkinase_Tyr PF07714.17 PRP87685.1 - 8e-19 67.9 0.1 2e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Helicase_C PF00271.31 PRP87685.1 - 6.1e-18 65.2 0.0 5e-17 62.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP87685.1 - 4.6e-11 43.0 2.1 4.1e-10 39.9 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Drc1-Sld2 PF11719.8 PRP87685.1 - 5.4e-05 22.9 18.1 5.4e-05 22.9 18.1 4.4 3 1 0 4 4 4 1 DNA replication and checkpoint protein Vpu PF00558.19 PRP87685.1 - 0.72 9.7 4.3 2.6 7.9 4.3 1.9 1 0 0 1 1 1 0 Vpu protein LUC7 PF03194.15 PRP87685.1 - 2.2 7.9 13.2 5.4 6.6 4.5 2.9 2 0 0 2 2 2 0 LUC7 N_terminus zf-RING_2 PF13639.6 PRP87686.1 - 4.9e-12 46.0 7.7 7.9e-12 45.3 7.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP87686.1 - 4.4e-09 36.0 6.1 7.9e-09 35.2 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP87686.1 - 4.9e-09 35.8 3.3 4.9e-09 35.8 3.3 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 PRP87686.1 - 1e-07 31.7 5.5 1.9e-07 30.9 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP87686.1 - 6e-07 29.6 7.0 1.5e-06 28.4 7.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PRP87686.1 - 1.5e-06 28.0 5.7 2.2e-06 27.4 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP87686.1 - 3.4e-06 27.0 3.0 6.8e-06 26.0 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP87686.1 - 6.6e-06 26.0 5.3 1.1e-05 25.3 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PRP87686.1 - 0.00043 20.1 6.6 0.00076 19.3 6.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PRP87686.1 - 0.0084 16.1 1.8 0.016 15.3 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PRP87686.1 - 0.033 13.8 6.2 0.054 13.1 6.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 PRP87686.1 - 0.055 13.8 4.9 0.13 12.5 4.9 1.7 1 1 0 1 1 1 0 RING-like domain FlxA PF14282.6 PRP87686.1 - 0.07 13.1 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 FlxA-like protein Prok-RING_1 PF14446.6 PRP87686.1 - 0.99 9.4 5.7 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Acyl_transf_1 PF00698.21 PRP87687.1 - 9.6e-28 97.6 0.2 1.4e-27 97.1 0.2 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 PRP87687.1 - 0.046 13.4 0.4 0.88 9.3 0.4 2.3 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis GSAP-16 PF14959.6 PRP87688.1 - 2.5e-18 65.9 0.0 7.3e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term ubiquitin PF00240.23 PRP87690.1 - 1.3e-130 425.3 31.0 1e-32 111.7 0.9 4.9 5 0 0 5 5 4 4 Ubiquitin family Rad60-SLD PF11976.8 PRP87690.1 - 3.3e-59 196.6 22.9 2e-14 53.2 1.0 4.7 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP87690.1 - 6e-20 71.5 11.6 0.0016 18.9 0.2 5.3 4 0 0 4 4 4 4 Ubiquitin-like domain CH PF00307.31 PRP87690.1 - 4.2e-19 68.7 0.0 1.3e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain PH PF00169.29 PRP87690.1 - 4.4e-17 62.5 0.9 1.7e-08 34.9 0.0 3.5 3 0 0 3 3 3 2 PH domain TBK1_ULD PF18396.1 PRP87690.1 - 4.7e-13 48.9 5.7 0.14 12.2 0.1 4.6 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP87690.1 - 2.2e-11 43.8 4.8 0.54 10.4 0.1 5.2 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PRP87690.1 - 2.6e-11 43.7 9.4 0.25 11.7 0.1 4.6 4 0 0 4 4 4 4 Ubiquitin-like domain DUF2407 PF10302.9 PRP87690.1 - 1.5e-10 41.5 6.7 0.92 10.1 0.0 5.5 2 1 1 5 5 4 4 DUF2407 ubiquitin-like domain LIM PF00412.22 PRP87690.1 - 3.9e-07 30.2 7.4 3.9e-07 30.2 7.4 2.4 2 0 0 2 2 2 1 LIM domain DUF3861 PF12977.7 PRP87690.1 - 0.0015 18.6 4.0 62 3.9 0.0 4.9 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 PRP87690.1 - 0.031 14.4 3.0 63 3.8 0.1 4.2 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF493 PF04359.14 PRP87690.1 - 0.041 14.5 0.1 3.2e+02 2.0 0.0 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF493) DUF1940 PF09155.10 PRP87690.1 - 0.068 13.3 3.7 1.3e+02 2.6 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1940) ACT_5 PF13710.6 PRP87690.1 - 0.099 12.5 5.4 1.1e+02 2.8 0.1 4.8 4 0 0 4 4 4 0 ACT domain MRP-L47 PF06984.13 PRP87691.1 - 1.7e-23 82.5 2.5 1.9e-23 82.4 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 PRP87691.1 - 0.0077 16.2 7.5 0.0077 16.2 7.5 2.4 2 1 0 2 2 2 1 Ribosomal L29 protein Bim_N PF06773.11 PRP87694.1 - 0.26 11.0 0.2 0.26 11.0 0.2 2.2 2 1 1 3 3 3 0 Bim protein N-terminus DENN PF02141.21 PRP87695.1 - 2.9e-42 144.7 0.4 5.4e-42 143.8 0.4 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain WD40 PF00400.32 PRP87695.1 - 1.2e-38 130.3 37.8 3e-06 27.9 0.1 9.1 9 0 0 9 9 9 8 WD domain, G-beta repeat uDENN PF03456.18 PRP87695.1 - 1.6e-12 48.0 0.2 4.4e-12 46.6 0.2 1.9 1 0 0 1 1 1 1 uDENN domain Nup160 PF11715.8 PRP87695.1 - 1.9e-07 30.1 11.3 0.0064 15.2 0.9 5.2 1 1 5 6 6 6 3 Nucleoporin Nup120/160 dDENN PF03455.19 PRP87695.1 - 9.4e-07 28.7 7.3 6.3e-06 26.1 1.1 3.2 3 0 0 3 3 3 1 dDENN domain WD40_like PF17005.5 PRP87695.1 - 0.00027 20.4 0.0 0.011 15.1 0.0 2.4 1 1 1 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 PRP87695.1 - 0.0006 20.1 0.8 17 5.8 0.0 5.0 2 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain SBF2 PF12335.8 PRP87695.1 - 0.0012 18.5 0.2 0.0012 18.5 0.2 1.9 2 0 0 2 2 2 1 Myotubularin protein DUF1217 PF06748.12 PRP87695.1 - 1.6 8.7 4.4 8.4 6.4 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1217) Med2 PF11214.8 PRP87695.1 - 4.2 7.6 9.6 10 6.4 0.7 2.7 2 0 0 2 2 2 0 Mediator complex subunit 2 Ubiq_cyt_C_chap PF03981.12 PRP87696.1 - 6.8e-31 107.2 0.0 1.6e-29 102.8 0.0 2.1 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Kelch_4 PF13418.6 PRP87697.1 - 6.2e-29 99.8 1.0 2.3e-11 43.5 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 PRP87697.1 - 3.4e-25 87.8 5.8 6.6e-08 32.7 0.1 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 PRP87697.1 - 9.4e-23 79.5 3.4 7e-10 38.3 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 PRP87697.1 - 8e-19 67.2 4.9 3.2e-07 30.4 0.1 5.1 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PRP87697.1 - 1.8e-17 62.5 1.0 2.7e-07 30.3 0.1 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 PRP87697.1 - 1.9e-15 56.4 3.2 9.9e-10 38.2 0.3 4.4 5 0 0 5 5 5 3 Kelch motif RAG2 PF03089.14 PRP87697.1 - 0.0074 15.3 0.1 1 8.3 0.0 2.3 2 0 0 2 2 2 2 Recombination activating protein 2 FKBP_C PF00254.28 PRP87698.1 - 8.9e-30 102.9 0.0 2.3e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 PRP87698.1 - 4.9e-17 62.4 0.1 2.5e-16 60.1 0.0 2.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 PRP87698.1 - 0.0011 19.5 0.1 0.003 18.0 0.1 1.7 1 0 0 1 1 1 1 Nucleoplasmin/nucleophosmin domain YL1 PF05764.13 PRP87698.1 - 0.0082 16.3 5.8 0.0082 16.3 5.8 1.7 2 0 0 2 2 2 1 YL1 nuclear protein CD20 PF04103.15 PRP87698.1 - 0.048 13.7 0.4 0.048 13.7 0.4 1.7 2 1 0 2 2 2 0 CD20-like family SRP-alpha_N PF04086.13 PRP87698.1 - 0.38 10.7 8.2 0.71 9.7 8.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pol_alpha_B_N PF08418.10 PRP87698.1 - 0.43 10.5 7.2 0.74 9.7 7.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Mitofilin PF09731.9 PRP87698.1 - 1.4 7.6 12.9 1.9 7.3 12.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cyt-b5 PF00173.28 PRP87699.1 - 1.8e-15 56.9 0.0 3.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 PRP87699.1 - 2.7e-13 50.4 12.1 2.7e-13 50.4 12.1 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MIF4G PF02854.19 PRP87700.1 - 1.1e-37 129.7 2.9 1.7e-37 129.1 2.9 1.3 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 PRP87700.1 - 2.7e-06 27.3 0.1 1.5e-05 25.0 0.0 2.3 2 1 1 3 3 3 1 MA3 domain Lectin_leg-like PF03388.13 PRP87701.1 - 7.1e-68 228.4 1.6 1.2e-67 227.6 1.6 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 PRP87701.1 - 6.1e-10 39.4 5.6 1.3e-09 38.3 5.6 1.5 1 0 0 1 1 1 1 Bacterial lectin DUF2730 PF10805.8 PRP87701.1 - 1.5e-05 25.0 1.2 0.0032 17.5 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2730) ALIX_LYPXL_bnd PF13949.6 PRP87701.1 - 0.0039 16.6 10.3 0.13 11.6 3.4 2.1 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV AAA_13 PF13166.6 PRP87701.1 - 0.0046 15.7 10.1 0.0084 14.8 10.1 1.4 1 0 0 1 1 1 1 AAA domain DUF4199 PF13858.6 PRP87701.1 - 0.0056 17.1 1.4 0.057 13.8 0.5 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) TolA_bind_tri PF16331.5 PRP87701.1 - 0.0097 16.0 18.8 0.14 12.2 7.3 3.5 2 1 2 4 4 3 2 TolA binding protein trimerisation Filament PF00038.21 PRP87701.1 - 0.0099 15.5 8.3 0.029 14.0 8.3 1.6 1 1 0 1 1 1 1 Intermediate filament protein CAMSAP_CC1 PF17095.5 PRP87701.1 - 0.015 15.2 1.3 0.11 12.3 0.1 2.5 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin ApoC-I PF04691.12 PRP87701.1 - 0.023 14.6 1.2 0.057 13.3 0.1 2.3 3 0 0 3 3 2 0 Apolipoprotein C-I (ApoC-1) DUF948 PF06103.11 PRP87701.1 - 0.025 14.8 4.7 0.09 13.0 0.6 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 PRP87701.1 - 0.051 14.1 10.1 0.22 12.0 0.9 3.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PRP87701.1 - 0.083 12.9 0.2 0.083 12.9 0.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 PRP87701.1 - 0.12 12.6 6.4 2.1 8.7 0.1 3.2 2 1 2 4 4 4 0 ABC transporter C-terminal domain PilO PF04350.13 PRP87701.1 - 0.14 12.4 8.1 0.66 10.1 0.2 2.9 1 1 2 3 3 3 0 Pilus assembly protein, PilO CENP-F_leu_zip PF10473.9 PRP87701.1 - 0.15 12.1 13.5 1.1 9.2 7.7 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WXG100 PF06013.12 PRP87701.1 - 0.16 12.2 8.1 0.26 11.5 1.9 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG CCDC144C PF14915.6 PRP87701.1 - 0.23 10.5 13.5 0.089 11.9 6.8 2.2 1 1 0 2 2 2 0 CCDC144C protein coiled-coil region FlaC_arch PF05377.11 PRP87701.1 - 0.31 11.5 8.4 11 6.5 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 PRP87701.1 - 0.55 10.4 25.7 0.07 13.3 10.3 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IFT57 PF10498.9 PRP87701.1 - 0.72 8.8 11.1 0.31 10.0 7.8 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Hormone_1 PF00103.20 PRP87701.1 - 0.8 9.4 4.3 4.5 7.0 2.0 2.4 2 1 0 2 2 2 0 Somatotropin hormone family Syntaxin-6_N PF09177.11 PRP87701.1 - 0.88 10.2 8.5 0.27 11.8 3.8 2.6 2 1 1 3 3 2 0 Syntaxin 6, N-terminal MscS_porin PF12795.7 PRP87701.1 - 1.2 8.6 27.8 1 8.8 4.3 2.5 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain EMP24_GP25L PF01105.24 PRP87701.1 - 1.5 8.7 13.1 9.4 6.1 6.2 3.2 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD FapA PF03961.13 PRP87701.1 - 1.8 7.1 10.9 0.51 8.9 6.5 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A BRE1 PF08647.11 PRP87701.1 - 1.8 8.7 11.4 1.3 9.1 0.3 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 PRP87701.1 - 2.5 8.5 17.3 0.31 11.5 9.5 2.1 1 1 1 2 2 2 0 Fez1 Sec34 PF04136.15 PRP87701.1 - 3.4 7.5 11.0 3.6 7.5 0.6 2.7 1 1 2 3 3 3 0 Sec34-like family Tropomyosin_1 PF12718.7 PRP87701.1 - 5.3 7.2 10.9 17 5.6 10.1 2.2 1 1 1 2 2 2 0 Tropomyosin like Med9 PF07544.13 PRP87701.1 - 5.7 7.1 11.2 4.9 7.3 2.5 3.6 2 1 2 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 APG6_N PF17675.1 PRP87701.1 - 8.6 6.9 17.3 16 6.0 2.9 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region HrpB7 PF09486.10 PRP87701.1 - 9 6.7 16.0 1.5 9.2 0.8 2.9 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Helicase_C PF00271.31 PRP87702.1 - 6.4e-21 74.8 0.0 1.1e-16 61.2 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 PRP87702.1 - 1.3e-16 60.8 0.1 3.7e-16 59.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 PRP87702.1 - 1e-14 55.0 1.8 4.6e-14 52.9 2.1 2.0 2 0 0 2 2 2 1 RecQ zinc-binding DHH PF01368.20 PRP87703.1 - 4.2e-07 30.1 0.0 7.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 DHH family SUKH-4 PF14435.6 PRP87703.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 SUKH-4 immunity protein RRM_1 PF00076.22 PRP87704.1 - 2.5e-19 68.8 0.1 4.5e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PRP87704.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 PRP87705.1 - 9.6e-05 22.2 10.2 0.0022 17.8 0.1 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PRP87705.1 - 0.00021 22.0 3.4 0.11 13.3 0.0 2.9 1 1 2 3 3 3 2 Torus domain zf-C3H1 PF10650.9 PRP87705.1 - 0.00054 19.6 5.4 0.049 13.4 0.6 3.1 3 1 1 4 4 4 2 Putative zinc-finger domain zf-CCCH_3 PF15663.5 PRP87705.1 - 0.00079 19.6 10.3 0.006 16.8 3.1 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf_CCCH_4 PF18345.1 PRP87705.1 - 0.00092 19.2 12.0 0.43 10.7 1.3 4.0 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 PRP87705.1 - 0.026 15.0 1.5 0.026 15.0 1.5 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 PRP87705.1 - 0.029 14.2 0.8 0.029 14.2 0.8 4.3 5 0 0 5 5 5 0 CCCH-type zinc finger CDC45 PF02724.14 PRP87706.1 - 0.015 13.6 4.3 0.02 13.2 4.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 PRP87706.1 - 0.027 14.8 8.2 0.058 13.8 8.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 PRP87706.1 - 0.036 12.3 8.3 0.046 12.0 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 PRP87706.1 - 0.084 13.2 5.5 0.18 12.1 5.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YL1 PF05764.13 PRP87706.1 - 0.094 12.8 14.4 0.14 12.2 14.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TFIIF_alpha PF05793.12 PRP87706.1 - 0.15 10.7 11.6 0.23 10.0 11.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 PRP87706.1 - 0.29 10.8 14.5 0.44 10.2 14.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 PRP87706.1 - 0.4 10.0 12.0 0.85 8.9 12.0 1.5 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 PRP87706.1 - 0.41 10.5 6.7 0.68 9.8 6.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 PRP87706.1 - 1 9.0 6.9 2.1 8.0 6.9 1.5 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 PRP87706.1 - 1.8 6.6 18.0 2.7 6.0 18.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4637 PF15470.6 PRP87706.1 - 2.3 7.9 8.7 4 7.2 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF2457 PF10446.9 PRP87706.1 - 3.1 6.9 14.3 4.6 6.3 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.11 PRP87706.1 - 8.3 4.4 6.0 12 3.8 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RhoGEF PF00621.20 PRP87707.1 - 7.9e-31 107.7 8.2 2e-21 77.1 1.3 4.0 2 2 1 3 3 3 3 RhoGEF domain PH PF00169.29 PRP87707.1 - 1.2e-10 41.8 0.8 2.6e-05 24.7 0.0 3.5 4 0 0 4 4 4 2 PH domain PH_13 PF16652.5 PRP87707.1 - 2.6e-06 27.3 0.2 1.7e-05 24.7 0.1 2.5 1 1 1 2 2 2 1 Pleckstrin homology domain TraD PF06412.11 PRP87707.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TraD PH_10 PF15411.6 PRP87707.1 - 0.12 12.6 0.2 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain adh_short PF00106.25 PRP87708.1 - 2.2e-19 69.7 0.9 1.1e-14 54.4 0.3 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP87708.1 - 1.1e-10 41.5 0.8 3.1e-08 33.5 0.4 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP87708.1 - 5.1e-06 26.5 0.5 1.1e-05 25.4 0.5 1.5 1 0 0 1 1 1 1 KR domain PRMT5 PF05185.16 PRP87708.1 - 0.05 13.5 2.0 0.1 12.5 0.0 2.1 2 1 0 2 2 2 0 PRMT5 arginine-N-methyltransferase NAD_binding_10 PF13460.6 PRP87708.1 - 0.17 11.7 1.8 0.27 11.1 0.9 1.8 1 1 0 1 1 1 0 NAD(P)H-binding CTP_transf_like PF01467.26 PRP87709.1 - 1.6e-23 83.5 0.0 2.1e-21 76.6 0.0 2.1 1 1 0 1 1 1 1 Cytidylyltransferase-like LCAT PF02450.15 PRP87710.1 - 1.1e-51 176.2 0.0 1.9e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ank_2 PF12796.7 PRP87710.1 - 2.3e-17 63.3 0.1 4.7e-07 30.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87710.1 - 1e-12 48.3 0.6 0.00044 20.8 0.1 4.4 1 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87710.1 - 2.2e-12 46.0 0.1 0.0054 17.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 PRP87710.1 - 2e-11 43.8 0.0 0.0006 20.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 PRP87710.1 - 2.2e-09 37.4 0.4 1.2e-05 25.5 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PGAP1 PF07819.13 PRP87710.1 - 0.00057 19.7 0.0 0.0056 16.4 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Lipase_2 PF01674.18 PRP87710.1 - 0.0036 16.9 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) DUF900 PF05990.12 PRP87710.1 - 0.0041 16.7 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 PRP87710.1 - 0.086 12.5 0.0 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 PRP87710.1 - 0.1 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 PRP87710.1 - 0.11 13.0 0.0 0.29 11.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3958 PF13125.6 PRP87711.1 - 0.073 13.3 6.0 0.18 12.0 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Ral PF11058.8 PRP87711.1 - 0.14 11.8 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Antirestriction protein Ral UBN_AB PF14075.6 PRP87711.1 - 0.32 10.7 5.1 0.078 12.7 1.6 1.7 2 0 0 2 2 2 0 Ubinuclein conserved middle domain TIM PF00121.18 PRP87713.1 - 7.5e-82 274.4 1.7 1.2e-81 273.7 1.7 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase Arrestin_N PF00339.29 PRP87713.1 - 7.1e-16 58.6 0.2 5.5e-12 46.0 0.1 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PRP87713.1 - 1.3e-14 54.7 0.2 2.5e-10 40.9 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain PaaA_PaaC PF05138.12 PRP87713.1 - 0.051 12.7 0.0 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein DUF4442 PF14539.6 PRP87713.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) LDB19 PF13002.7 PRP87713.1 - 0.086 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like Transmemb_17 PF09799.9 PRP87714.1 - 2.3e-14 53.9 0.9 2.3e-14 53.9 0.9 1.5 2 0 0 2 2 2 1 Predicted membrane protein DUF1290 PF06947.12 PRP87714.1 - 0.024 14.7 3.7 0.046 13.8 3.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1290) HATPase_c PF02518.26 PRP87715.1 - 3.4e-27 95.2 0.0 6.4e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP87715.1 - 2.3e-21 76.0 0.6 5.9e-21 74.7 0.6 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 PRP87715.1 - 1.1e-15 57.4 0.3 4.1e-15 55.6 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain MASE3 PF17159.4 PRP87715.1 - 9.4e-14 51.6 22.7 9.4e-14 51.6 22.7 1.4 1 1 0 1 1 1 1 Membrane-associated sensor domain PAS_9 PF13426.7 PRP87715.1 - 0.018 15.3 0.1 0.13 12.6 0.2 2.5 2 1 0 2 2 2 0 PAS domain Sec34 PF04136.15 PRP87716.1 - 1.8e-42 144.8 4.4 1.8e-42 144.8 4.4 2.9 4 0 0 4 4 4 1 Sec34-like family LapA_dom PF06305.11 PRP87717.1 - 0.19 11.5 2.6 1.4 8.8 0.2 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TMEM43 PF07787.12 PRP87717.1 - 0.66 9.3 4.1 2.1 7.7 4.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 43 Guanylate_kin PF00625.21 PRP87718.1 - 1.3e-59 200.9 0.0 2.3e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase dUTPase PF00692.19 PRP87718.1 - 2.1e-37 127.7 0.0 4.1e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 dUTPase PHD PF00628.29 PRP87718.1 - 7.8e-10 38.5 6.7 7.8e-10 38.5 6.7 2.2 2 1 0 2 2 1 1 PHD-finger PHD_2 PF13831.6 PRP87718.1 - 2.1e-05 23.9 1.1 7.4e-05 22.2 1.1 2.0 1 0 0 1 1 1 1 PHD-finger RsgA_GTPase PF03193.16 PRP87718.1 - 0.00012 22.1 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase JmjC PF02373.22 PRP87718.1 - 0.00069 20.0 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase MMR_HSR1 PF01926.23 PRP87718.1 - 0.00082 19.4 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 PRP87718.1 - 0.0051 17.0 0.0 0.028 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 PRP87718.1 - 0.0064 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 PRP87718.1 - 0.0091 16.5 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PRP87718.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PHD_3 PF13922.6 PRP87718.1 - 0.018 15.4 0.1 0.018 15.4 0.1 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx AAA_18 PF13238.6 PRP87718.1 - 0.051 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 PRP87718.1 - 0.083 13.1 0.2 0.32 11.2 0.0 2.1 3 0 0 3 3 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PRP87718.1 - 0.18 12.1 0.0 0.51 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ZZ PF00569.17 PRP87718.1 - 0.75 9.7 12.1 0.038 13.8 6.2 1.9 2 0 0 2 2 1 0 Zinc finger, ZZ type ABC2_membrane PF01061.24 PRP87719.1 - 2.2e-84 282.1 59.9 9.6e-43 146.0 26.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 PRP87719.1 - 4.4e-38 130.9 0.0 1.1e-19 71.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 PRP87719.1 - 2.5e-27 94.6 0.7 1.1e-23 82.9 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 PRP87719.1 - 2.2e-07 31.4 0.3 5.8e-07 30.0 0.3 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 PRP87719.1 - 2.4e-06 27.2 0.0 0.0043 16.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PRP87719.1 - 1.3e-05 25.2 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PRP87719.1 - 2.1e-05 24.8 0.0 0.08 13.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PRP87719.1 - 2.3e-05 24.4 0.1 0.001 19.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 PRP87719.1 - 4.1e-05 24.0 0.0 0.088 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 PRP87719.1 - 0.00034 20.3 0.1 0.0015 18.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 PRP87719.1 - 0.0028 16.9 22.7 0.0028 16.9 22.7 3.3 2 2 1 3 3 3 1 ABC-2 family transporter protein Zeta_toxin PF06414.12 PRP87719.1 - 0.0044 16.3 0.0 0.082 12.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 PRP87719.1 - 0.011 15.9 0.7 0.16 12.2 0.5 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PRP87719.1 - 0.013 16.0 0.2 0.43 11.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PRP87719.1 - 0.013 15.6 1.3 0.33 11.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 PRP87719.1 - 0.024 14.7 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 PRP87719.1 - 0.064 12.8 0.2 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 PRP87719.1 - 0.1 12.3 2.6 1.5 8.5 0.6 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 PRP87719.1 - 0.24 11.8 1.4 13 6.2 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PRP87719.1 - 0.24 11.3 1.0 4.7 7.1 0.3 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 PRP87719.1 - 1.9 9.0 6.8 0.63 10.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain Sid-5 PF17204.3 PRP87719.1 - 2.1 8.6 3.6 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Sid-5 family AAA_23 PF13476.6 PRP87720.1 - 0.05 14.1 1.0 0.085 13.3 1.0 1.3 1 0 0 1 1 1 0 AAA domain PurK_C PF17769.1 PRP87720.1 - 0.11 12.2 0.6 0.26 11.0 0.2 1.9 2 0 0 2 2 2 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain PAS_6 PF08348.11 PRP87721.1 - 0.053 13.4 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 YheO-like PAS domain Ank_2 PF12796.7 PRP87723.1 - 1.2e-08 35.4 0.8 0.019 15.5 0.0 4.6 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87723.1 - 3.8e-08 33.7 13.2 0.44 11.2 0.0 8.3 8 2 2 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87723.1 - 5.1e-07 29.5 1.1 26 5.8 0.0 8.4 10 1 1 11 11 11 1 Ankyrin repeat Ank_5 PF13857.6 PRP87723.1 - 7.5e-07 29.3 8.5 0.55 10.6 0.0 6.6 7 1 1 8 8 8 4 Ankyrin repeats (many copies) zf-C3HC PF07967.13 PRP87723.1 - 0.19 11.7 1.1 0.32 11.0 0.1 1.8 2 0 0 2 2 2 0 C3HC zinc finger-like Methyltr_RsmB-F PF01189.17 PRP87724.1 - 1.6e-30 106.2 0.0 2.7e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PRP87724.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 PRP87724.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Arabinose_Isome PF02610.15 PRP87724.1 - 0.031 13.5 0.7 0.053 12.7 0.7 1.4 1 0 0 1 1 1 0 L-arabinose isomerase HlyIII PF03006.20 PRP87725.1 - 5.5e-50 170.2 24.8 5.5e-50 170.2 24.8 2.6 2 0 0 2 2 2 1 Haemolysin-III related B_lectin PF01453.24 PRP87725.1 - 2.4e-06 28.1 37.5 0.0063 17.0 0.4 8.9 9 1 1 10 10 10 3 D-mannose binding lectin LRR_8 PF13855.6 PRP87725.1 - 7.2e-06 25.7 28.1 9.3e-05 22.1 5.6 4.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 PRP87725.1 - 0.00038 20.8 38.5 0.003 17.9 7.6 6.0 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) SNF2_N PF00176.23 PRP87727.1 - 7.6e-63 212.3 0.1 1.9e-62 211.0 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 PRP87727.1 - 5.5e-22 77.4 0.0 6e-14 51.7 0.0 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 PRP87727.1 - 4.7e-21 75.2 0.0 1.1e-20 74.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 PRP87727.1 - 5e-12 46.1 2.4 5e-12 46.1 2.4 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) CHDCT2 PF08074.11 PRP87727.1 - 0.001 19.3 0.6 0.001 19.3 0.6 2.3 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain SLIDE PF09111.10 PRP87727.1 - 0.0011 19.0 0.1 0.0011 19.0 0.1 3.5 3 1 0 3 3 3 1 SLIDE Myb_DNA-binding PF00249.31 PRP87727.1 - 0.0024 18.0 0.3 0.0087 16.2 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Josephin PF02099.17 PRP87727.1 - 0.14 12.3 1.7 0.81 9.8 1.7 2.4 1 0 0 1 1 1 0 Josephin Peptidase_S8 PF00082.22 PRP87728.1 - 1.4e-40 139.4 8.7 1.8e-40 139.1 8.7 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 PRP87728.1 - 8e-15 54.6 0.3 2.3e-14 53.2 0.3 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain Cation_ATPase_C PF00689.21 PRP87729.1 - 6.1e-35 120.6 11.8 6.1e-35 120.6 11.8 2.4 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PRP87729.1 - 1.3e-33 116.0 0.0 1.3e-33 116.0 0.0 3.7 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 PRP87729.1 - 1.2e-18 68.1 1.5 5.3e-18 66.1 1.5 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PRP87729.1 - 3.7e-12 45.7 0.0 8.9e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PRP87729.1 - 1.8e-09 37.6 0.0 1.1e-08 35.0 0.0 2.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 PRP87729.1 - 1.2e-05 25.1 2.9 0.00013 21.8 1.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LIM PF00412.22 PRP87730.1 - 2.5e-13 50.0 7.9 2.5e-13 50.0 7.9 2.3 3 0 0 3 3 3 1 LIM domain DZR PF12773.7 PRP87730.1 - 0.02 14.9 23.4 0.98 9.5 3.9 4.1 2 2 1 3 3 3 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 PRP87730.1 - 0.1 12.4 0.7 0.1 12.4 0.7 5.2 4 1 1 5 5 5 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 PRP87730.1 - 0.51 10.1 0.2 0.51 10.1 0.2 4.5 5 0 0 5 5 5 0 NADH pyrophosphatase zinc ribbon domain zf-RRN7 PF11781.8 PRP87730.1 - 0.56 9.9 18.5 0.54 10.0 0.3 5.0 4 1 0 4 4 4 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 UPF0547 PF10571.9 PRP87730.1 - 0.97 9.6 0.1 0.97 9.6 0.1 4.2 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 PRP87730.1 - 1 9.4 16.1 0.99 9.4 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbons T4_baseplate PF12322.8 PRP87730.1 - 1.9 7.9 3.4 0.53 9.7 0.3 1.6 2 0 0 2 2 2 0 T4 bacteriophage base plate protein HypA PF01155.19 PRP87730.1 - 2 8.5 15.8 1.1 9.3 0.2 2.9 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_UBZ PF18439.1 PRP87730.1 - 2.7 7.7 19.3 3.2 7.4 0.5 5.1 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger DNA_RNApol_7kD PF03604.13 PRP87730.1 - 8.6 6.1 16.7 22 4.8 0.2 4.7 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit SMC_Nse1 PF07574.13 PRP87731.1 - 6.7e-25 88.1 0.4 3.2e-24 85.9 0.4 1.9 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 PRP87731.1 - 4e-08 33.4 11.7 6.1e-08 32.9 11.7 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 PRP87731.1 - 0.0032 17.8 12.0 0.006 16.9 12.0 1.5 1 0 0 1 1 1 1 Ring finger domain DUF4796 PF16044.5 PRP87731.1 - 0.044 13.4 2.2 2.4 7.7 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) zf-ANAPC11 PF12861.7 PRP87731.1 - 0.079 13.0 5.9 0.13 12.3 5.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SF-assemblin PF06705.11 PRP87731.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin zf-RING_9 PF13901.6 PRP87731.1 - 0.24 11.4 8.8 0.88 9.5 8.8 1.8 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.8 PRP87731.1 - 0.66 10.2 10.3 1.3 9.2 9.0 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PRP87731.1 - 2 8.1 9.7 3.4 7.4 9.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 PRP87731.1 - 5.5 7.4 13.0 4.9 7.5 11.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PRP87733.1 - 1.7e-13 50.7 4.8 2.6e-13 50.1 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PRP87733.1 - 5.9e-11 42.5 2.8 1.3e-10 41.3 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PRP87733.1 - 2.6e-10 39.8 2.8 5.6e-10 38.8 2.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PRP87733.1 - 5.3e-09 35.8 4.4 8.6e-09 35.1 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP87733.1 - 3.4e-08 33.2 3.1 5.5e-08 32.5 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP87733.1 - 2.8e-07 30.4 2.2 4.5e-07 29.7 2.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PRP87733.1 - 1.7e-06 28.0 1.7 3.2e-06 27.1 1.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP87733.1 - 1.2e-05 25.1 1.8 1.8e-05 24.5 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP87733.1 - 3.3e-05 23.6 2.1 6.7e-05 22.7 2.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PRP87733.1 - 0.0024 17.9 3.3 0.0061 16.6 3.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PRP87733.1 - 0.015 15.4 4.9 0.047 13.8 4.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 PRP87733.1 - 0.056 13.1 2.9 0.1 12.2 2.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Borrelia_P83 PF05262.11 PRP87733.1 - 0.091 11.2 5.5 0.12 10.8 5.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PHD PF00628.29 PRP87733.1 - 0.12 12.3 4.1 0.24 11.3 4.1 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 PRP87733.1 - 0.15 12.3 5.1 0.62 10.3 5.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 PRP87733.1 - 0.21 11.4 4.1 0.39 10.6 4.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zf_RING PF16744.5 PRP87733.1 - 0.36 11.0 3.0 0.86 9.8 2.6 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 PRP87733.1 - 1.4 9.1 5.1 4.1 7.6 5.1 1.8 1 1 0 1 1 1 0 RING-variant domain OmpH PF03938.14 PRP87733.1 - 2.8 8.3 10.1 4.7 7.5 10.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CTU2 PF10288.9 PRP87733.1 - 6.9 7.0 7.6 39 4.5 7.6 2.3 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 EF1_GNE PF00736.19 PRP87734.1 - 7.4e-32 109.4 2.8 1.4e-31 108.5 2.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Stm1_N PF09598.10 PRP87734.1 - 0.00043 21.1 0.8 0.00043 21.1 0.8 2.3 2 0 0 2 2 2 1 Stm1 DUF3484 PF11983.8 PRP87734.1 - 0.028 15.5 2.4 0.028 15.5 2.4 2.0 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Unstab_antitox PF09720.10 PRP87734.1 - 0.085 12.9 4.3 4.2 7.5 0.9 2.5 2 0 0 2 2 2 0 Putative addiction module component PBP1_TM PF14812.6 PRP87734.1 - 0.11 12.9 7.6 0.2 12.0 7.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spot_14 PF07084.12 PRP87734.1 - 0.18 11.9 1.7 0.34 11.0 1.3 1.9 1 1 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 TP53IP5 PF15331.6 PRP87734.1 - 0.29 11.3 5.0 0.47 10.6 5.0 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Presenilin PF01080.17 PRP87734.1 - 0.86 8.3 3.6 1.1 8.0 3.6 1.1 1 0 0 1 1 1 0 Presenilin 3HCDH_N PF02737.18 PRP87734.1 - 1.6 8.5 7.9 0.093 12.6 2.2 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sec62 PF03839.16 PRP87734.1 - 9.1 5.7 6.9 13 5.2 6.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SUI1 PF01253.22 PRP87735.1 - 8.1e-24 84.0 1.1 1.9e-23 82.8 1.1 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 SH3_1 PF00018.28 PRP87735.1 - 3.5e-22 77.7 3.9 2.9e-10 39.6 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 PRP87735.1 - 1.2e-20 72.9 0.5 7.2e-10 38.4 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.6 PRP87735.1 - 1.6e-19 69.5 5.1 4.8e-10 39.1 0.5 2.6 3 0 0 3 3 3 2 Variant SH3 domain EMC3_TMCO1 PF01956.16 PRP87735.1 - 0.16 11.7 3.7 0.3 10.8 3.7 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2052 PF09747.9 PRP87735.1 - 0.33 11.1 10.7 0.73 9.9 10.7 1.7 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NARP1 PF12569.8 PRP87735.1 - 0.39 9.6 16.1 0.61 8.9 16.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 PRP87735.1 - 0.87 9.4 17.9 1.7 8.4 17.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 PRP87735.1 - 2.7 8.1 9.6 5.8 7.1 9.6 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_polI_A34 PF08208.11 PRP87735.1 - 3.5 7.6 30.9 13 5.9 30.8 1.9 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SMYLE_N PF18615.1 PRP87735.1 - 4.1 6.9 12.4 7.6 6.0 12.4 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Peptidase_S49_N PF08496.10 PRP87735.1 - 4.8 7.2 12.8 12 6.0 12.8 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ATG101 PF07855.12 PRP87736.1 - 2.8e-34 118.3 0.2 3.7e-34 117.9 0.2 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 NOG1_N PF17835.1 PRP87737.1 - 9.3e-53 178.5 0.5 9.3e-53 178.5 0.5 2.7 4 0 0 4 4 4 1 NOG1 N-terminal helical domain NOG1 PF06858.14 PRP87737.1 - 3.5e-27 94.0 1.1 2.8e-26 91.1 0.1 2.5 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 PRP87737.1 - 1.6e-18 66.8 0.0 3.8e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.11 PRP87737.1 - 1.3e-16 60.3 1.2 3.3e-16 59.0 1.2 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.18 PRP87737.1 - 1.5e-12 47.3 0.0 2.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP87737.1 - 0.00041 20.3 0.0 0.14 12.0 0.0 2.9 2 1 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 PRP87737.1 - 0.00091 18.6 0.1 0.0086 15.4 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 PRP87737.1 - 0.0016 18.5 0.0 0.5 10.4 0.0 2.9 1 1 1 2 2 2 1 Dynamin family Ras PF00071.22 PRP87737.1 - 0.009 15.6 0.0 0.027 14.1 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PRP87737.1 - 0.017 15.3 0.0 0.24 11.6 0.0 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NEL PF14496.6 PRP87737.1 - 0.024 14.0 0.2 0.78 9.1 0.1 2.9 3 0 0 3 3 3 0 C-terminal novel E3 ligase, LRR-interacting AAA_16 PF13191.6 PRP87737.1 - 0.14 12.5 0.3 0.68 10.3 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain TP2 PF01254.18 PRP87737.1 - 0.79 10.3 3.6 1.8 9.2 3.6 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 DUF1084 PF06454.11 PRP87739.1 - 0.0024 17.3 23.2 0.011 15.2 23.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) CDC27 PF09507.10 PRP87739.1 - 2.7 7.3 27.5 4.3 6.6 27.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDRGK PF09756.9 PRP87739.1 - 6.8 6.2 31.3 14 5.2 31.3 1.5 1 0 0 1 1 1 0 DDRGK domain MORN PF02493.20 PRP87740.1 - 1.8e-18 65.2 17.8 5.4e-05 22.8 0.1 4.5 4 0 0 4 4 4 4 MORN repeat PH PF00169.29 PRP87740.1 - 0.04 14.4 0.3 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 PH domain DEP PF00610.21 PRP87741.1 - 1.2e-07 31.7 0.0 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF547 PF04784.14 PRP87741.1 - 5.4e-06 26.4 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF547 SART-1 PF03343.13 PRP87742.1 - 2e-78 264.6 83.5 1.8e-66 225.1 82.7 3.4 2 1 1 3 3 3 2 SART-1 family His_Phos_1 PF00300.22 PRP87743.1 - 2.2e-28 99.3 0.3 4.2e-28 98.4 0.3 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Gag_p10 PF02337.17 PRP87743.1 - 0.089 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral GAG p10 protein UL11 PF11094.8 PRP87743.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated tegument protein 5HT_transport_N PF03491.13 PRP87744.1 - 0.097 12.9 0.3 0.31 11.3 0.3 1.8 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Phosducin PF02114.16 PRP87745.1 - 3.1e-19 69.0 2.9 2.5e-18 66.0 2.9 1.9 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 PRP87745.1 - 0.0024 17.8 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Dak1_2 PF13684.6 PRP87745.1 - 0.0064 15.6 0.2 0.0085 15.2 0.2 1.1 1 0 0 1 1 1 1 Dihydroxyacetone kinase family DIM1 PF02966.16 PRP87745.1 - 0.02 14.7 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Luteo_Vpg PF01659.16 PRP87746.1 - 0.053 13.9 0.9 0.09 13.1 0.9 1.4 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Chitin_bind_1 PF00187.19 PRP87747.1 - 4.6e-08 33.4 20.2 4.6e-08 33.4 20.2 2.7 2 1 0 2 2 2 1 Chitin recognition protein PAN_4 PF14295.6 PRP87747.1 - 6.2e-08 32.4 4.1 6.2e-08 32.4 4.1 2.6 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PRP87747.1 - 3.1e-05 23.9 0.4 9.2e-05 22.3 0.2 1.9 2 0 0 2 2 2 1 PAN domain Lyase_8 PF02278.18 PRP87748.1 - 3.3e-41 141.5 0.6 3.3e-41 141.5 0.6 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 PRP87748.1 - 3.6e-20 72.1 0.1 1e-19 70.7 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 PRP87748.1 - 1e-12 48.4 0.1 2.7e-12 47.0 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain He_PIG PF05345.12 PRP87748.1 - 0.023 14.9 0.2 0.099 12.8 0.2 2.1 1 0 0 1 1 1 0 Putative Ig domain ADH_N PF08240.12 PRP87750.1 - 9.7e-25 86.6 3.9 1.8e-24 85.7 3.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PRP87750.1 - 3.3e-18 65.9 0.0 6.4e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP87750.1 - 7.1e-07 30.3 0.0 1.1e-06 29.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PRP87750.1 - 0.00012 21.6 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 PRP87750.1 - 0.00043 19.7 0.2 0.00073 19.0 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 PRP87750.1 - 0.0035 16.7 0.1 0.006 15.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Hexapep_2 PF14602.6 PRP87750.1 - 0.02 14.6 2.7 1.3 8.8 1.1 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Mito_carr PF00153.27 PRP87751.1 - 2.5e-60 200.4 1.6 2.2e-21 75.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PRP87751.1 - 0.0016 17.6 2.3 1.7 7.8 0.0 3.2 3 1 1 4 4 4 2 Gammaproteobacterial serine protease GTP_EFTU_D2 PF03144.25 PRP87751.1 - 0.046 14.1 0.0 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu domain 2 RabGAP-TBC PF00566.18 PRP87753.1 - 1.5e-42 145.7 6.3 2.4e-42 145.0 6.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 PRP87753.1 - 2.5e-20 72.6 0.0 6.3e-15 55.1 0.0 2.4 1 1 1 2 2 2 2 Rab-binding domain (RBD) Pro-kuma_activ PF09286.11 PRP87753.1 - 1.3e-15 57.9 0.0 3.7e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP87753.1 - 4.7e-10 39.2 1.0 8e-10 38.5 1.0 1.3 1 0 0 1 1 1 1 Subtilase family Cyt-b5 PF00173.28 PRP87753.1 - 3e-05 24.1 0.1 9.1e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain R3H PF01424.22 PRP87753.1 - 0.054 13.5 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 R3H domain Wound_ind PF08186.11 PRP87753.1 - 0.3 11.6 1.3 1.1 9.8 0.4 2.3 2 0 0 2 2 2 0 Wound-inducible basic protein family Diphthami_syn_2 PF01902.17 PRP87754.1 - 8.1e-05 22.2 0.0 0.032 13.7 0.0 3.1 2 1 0 2 2 2 2 Diphthamide synthase Pkinase_Tyr PF07714.17 PRP87755.1 - 1.3e-45 155.7 0.1 1.8e-45 155.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87755.1 - 1.7e-31 109.5 0.1 2.8e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP87755.1 - 5.5e-10 39.6 5.7 1.6e-09 38.1 5.7 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP87755.1 - 0.0041 16.5 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Adeno_E1B_55K PF01696.17 PRP87755.1 - 0.01 14.5 0.4 0.01 14.5 0.4 2.5 2 1 1 3 3 3 0 Adenovirus EB1 55K protein / large t-antigen Kdo PF06293.14 PRP87755.1 - 0.017 14.5 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chlam_PMP PF02415.17 PRP87755.1 - 0.14 12.7 0.2 0.14 12.7 0.2 6.4 6 1 0 6 6 6 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pkinase_Tyr PF07714.17 PRP87756.1 - 1.1e-19 70.7 0.0 1.4e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87756.1 - 4.3e-07 29.6 0.0 8.7e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Diphthami_syn_2 PF01902.17 PRP87757.1 - 8.1e-05 22.2 0.0 0.032 13.7 0.0 3.1 2 1 0 2 2 2 2 Diphthamide synthase Pro-kuma_activ PF09286.11 PRP87758.1 - 6.5e-16 58.9 0.0 1.6e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP87758.1 - 1.6e-10 40.7 1.0 3.2e-10 39.8 1.0 1.4 1 0 0 1 1 1 1 Subtilase family Cyt-b5 PF00173.28 PRP87758.1 - 1.7e-05 24.9 0.0 4.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain R3H PF01424.22 PRP87758.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 R3H domain RabGAP-TBC PF00566.18 PRP87760.1 - 3.4e-43 147.8 6.3 5.4e-43 147.2 6.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 PRP87760.1 - 3.6e-21 75.4 0.0 2.1e-15 56.6 0.0 2.3 1 1 1 2 2 2 2 Rab-binding domain (RBD) Wound_ind PF08186.11 PRP87760.1 - 0.15 12.5 0.4 0.39 11.2 0.4 1.7 1 0 0 1 1 1 0 Wound-inducible basic protein family Mito_carr PF00153.27 PRP87761.1 - 1.5e-60 201.1 1.4 2.1e-21 75.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PRP87761.1 - 0.0017 17.5 2.7 1.6 7.9 0.0 3.2 3 1 0 4 4 4 2 Gammaproteobacterial serine protease ADH_N PF08240.12 PRP87762.1 - 1.1e-24 86.4 3.9 2e-24 85.6 3.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PRP87762.1 - 3.8e-18 65.7 0.0 7.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP87762.1 - 2.3e-07 31.9 0.0 3.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PRP87762.1 - 0.00014 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 PRP87762.1 - 0.00047 19.6 0.1 0.00079 18.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 PRP87762.1 - 0.0039 16.5 0.1 0.0067 15.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Hexapep_2 PF14602.6 PRP87762.1 - 0.024 14.4 2.7 1.4 8.7 1.1 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Lyase_8 PF02278.18 PRP87764.1 - 1.1e-41 143.0 0.6 2.7e-41 141.7 0.6 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 PRP87764.1 - 5.5e-21 74.8 0.1 1.6e-20 73.3 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 PRP87764.1 - 9.7e-13 48.4 0.1 2.4e-12 47.1 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain He_PIG PF05345.12 PRP87764.1 - 0.023 14.9 0.2 0.089 13.0 0.2 2.0 1 0 0 1 1 1 0 Putative Ig domain Ribosomal_L30 PF00327.20 PRP87765.1 - 2.6e-10 40.0 0.0 3.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SH3_10 PF17902.1 PRP87765.1 - 0.064 13.3 0.1 0.096 12.8 0.1 1.3 1 0 0 1 1 1 0 SH3 domain ILEI PF15711.5 PRP87765.1 - 0.073 13.6 0.0 0.079 13.5 0.0 1.1 1 0 0 1 1 1 0 Interleukin-like EMT inducer Pribosyltran PF00156.27 PRP87765.1 - 0.17 11.4 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyl transferase domain NIF PF03031.18 PRP87766.1 - 1.1e-22 80.5 0.0 4e-22 78.6 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PDEase_I PF00233.19 PRP87767.1 - 2.2e-77 260.0 6.5 2.2e-77 260.0 6.5 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 PRP87767.1 - 3.1e-07 30.5 0.0 1e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain OKR_DC_1_N PF03709.15 PRP87767.1 - 0.0036 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain ORC5_C PF14630.6 PRP87768.1 - 4.6e-41 141.2 0.5 7.3e-41 140.6 0.5 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Cyt-b5 PF00173.28 PRP87768.1 - 1.5e-21 76.3 0.1 2.9e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_16 PF13191.6 PRP87768.1 - 6.1e-07 30.0 0.0 2.2e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 PRP87768.1 - 0.0029 16.9 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 PRP87768.1 - 0.0095 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 PRP87768.1 - 0.011 16.1 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PRP87768.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PRP87768.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 PRP87768.1 - 0.026 15.1 0.0 0.083 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PRP87768.1 - 0.041 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 PRP87768.1 - 0.048 12.8 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 PRP87768.1 - 0.05 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PRP87768.1 - 0.092 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 PRP87768.1 - 0.11 12.1 0.0 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Viral_helicase1 PF01443.18 PRP87768.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 PRP87768.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NodZ PF05830.11 PRP87769.1 - 0.059 12.2 0.1 0.069 11.9 0.1 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) DUF3601 PF12208.8 PRP87769.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) NDK PF00334.19 PRP87770.1 - 0.02 14.9 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Nucleoside diphosphate kinase DSBA PF01323.20 PRP87772.1 - 1.1e-25 90.5 0.0 1.4e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 PRP87772.1 - 1.4e-06 28.6 0.0 1.1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.6 PRP87772.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Nkap_C PF06047.11 PRP87773.1 - 0.08 13.1 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain F_actin_cap_B PF01115.17 PRP87774.1 - 1.8e-106 355.1 0.0 2.6e-106 354.6 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Histone PF00125.24 PRP87774.1 - 1.9e-49 167.4 4.3 6.3e-49 165.7 1.4 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PRP87774.1 - 0.00026 21.6 0.3 0.00054 20.6 0.3 1.7 1 0 0 1 1 1 1 PCNA-associated factor histone like domain F-actin_cap_A PF01267.17 PRP87774.1 - 0.0019 17.7 0.6 0.015 14.8 0.2 2.5 2 1 0 2 2 2 1 F-actin capping protein alpha subunit PAC4 PF16093.5 PRP87774.1 - 0.0021 18.2 0.0 0.0075 16.4 0.0 2.0 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 CENP-T_C PF15511.6 PRP87774.1 - 0.0028 17.8 0.0 0.007 16.5 0.0 1.7 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PRP87774.1 - 0.006 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 CENP-S protein YqfQ PF14181.6 PRP87774.1 - 0.012 15.8 0.3 0.026 14.7 0.3 1.5 1 0 0 1 1 1 0 YqfQ-like protein TFIID-31kDa PF02291.15 PRP87774.1 - 0.05 13.7 0.9 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 PRP87774.1 - 0.064 13.5 0.1 0.16 12.3 0.1 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Atg14 PF10186.9 PRP87775.1 - 3.4e-12 46.1 9.4 6e-12 45.3 9.4 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Endopep_inhib PF16800.5 PRP87776.1 - 0.21 11.5 7.1 0.25 11.3 3.2 2.7 2 1 0 2 2 2 0 IseA DL-endopeptidase inhibitor zf-C2H2 PF00096.26 PRP87777.1 - 0.023 15.1 0.2 0.058 13.9 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type GST_C_3 PF14497.6 PRP87779.1 - 1.5e-17 63.6 0.1 1.9e-16 60.1 0.0 2.9 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain ETC_C1_NDUFA4 PF04800.12 PRP87780.1 - 2e-23 82.4 0.0 2.7e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 PRP87780.1 - 0.017 15.2 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Exo_endo_phos PF03372.23 PRP87781.1 - 1.6e-08 34.3 0.1 4.2e-08 33.0 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 PRP87781.1 - 0.062 13.2 1.4 0.15 11.9 0.1 2.3 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Zn_clus PF00172.18 PRP87782.1 - 1.2e-06 28.5 14.6 1.2e-06 28.5 14.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 PRP87782.1 - 0.0033 17.4 0.0 0.008 16.2 0.0 1.7 1 0 0 1 1 1 1 PAS fold MIP PF00230.20 PRP87783.1 - 2.1e-46 158.5 6.6 3.2e-46 157.9 6.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.25 PRP87784.1 - 8.4e-66 222.0 0.2 1.1e-65 221.7 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87784.1 - 1.6e-33 116.1 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP87784.1 - 1e-06 27.8 0.0 2.2e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP87784.1 - 4.9e-06 26.1 0.0 1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 PRP87784.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PRP87784.1 - 0.02 14.3 0.4 0.038 13.4 0.4 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP87784.1 - 0.032 13.8 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Methyltransf_13 PF08421.11 PRP87784.1 - 0.071 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative zinc binding domain Pkinase PF00069.25 PRP87785.1 - 0.00078 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87785.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 PRP87787.1 - 8.4e-15 55.1 0.0 2e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87787.1 - 5.5e-13 49.2 0.3 0.0022 18.5 0.0 3.4 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP87787.1 - 6.1e-06 26.5 0.0 0.92 10.1 0.0 4.5 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 PRP87787.1 - 3.6e-05 24.0 0.0 2.8 8.4 0.0 4.6 2 2 3 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87787.1 - 0.022 15.3 0.0 25 5.9 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat VapB_antitoxin PF09957.9 PRP87787.1 - 0.051 13.5 0.3 2.4 8.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial antitoxin of type II TA system, VapB DUF3618 PF12277.8 PRP87787.1 - 0.97 9.7 5.9 8.8 6.7 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) PPR_2 PF13041.6 PRP87788.1 - 0.0057 16.8 0.3 5 7.4 0.0 3.9 3 1 1 4 4 4 1 PPR repeat family YozD PF14162.6 PRP87788.1 - 0.02 15.2 0.1 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 YozD-like protein Phage_holin_6_1 PF09682.10 PRP87788.1 - 0.029 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) PPR PF01535.20 PRP87788.1 - 0.031 14.5 0.4 50 4.5 0.0 3.8 4 0 0 4 4 4 0 PPR repeat ATP13 PF12921.7 PRP87788.1 - 0.063 13.1 0.0 0.48 10.3 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial ATPase expression Cyt-b5 PF00173.28 PRP87789.1 - 7e-08 32.5 0.0 8.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain C2 PF00168.30 PRP87790.1 - 1.1e-20 73.9 0.1 1.8e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 C2 domain EcsB PF05975.12 PRP87790.1 - 0.0027 16.6 2.6 0.0039 16.1 2.6 1.2 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB CEP76-C2 PF15627.6 PRP87790.1 - 0.0032 17.0 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain 2TM PF13239.6 PRP87790.1 - 0.61 10.4 3.7 1.2 9.5 3.7 1.4 1 0 0 1 1 1 0 2TM domain 7tm_6 PF02949.20 PRP87791.1 - 0.0052 15.9 0.1 0.13 11.3 0.0 2.1 2 0 0 2 2 2 2 7tm Odorant receptor DUF5344 PF17279.2 PRP87791.1 - 0.008 16.7 0.1 0.033 14.7 0.0 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5344) FlgN PF05130.12 PRP87791.1 - 0.075 13.5 0.7 0.22 12.0 0.1 2.0 2 2 0 2 2 2 0 FlgN protein Pkinase_Tyr PF07714.17 PRP87792.1 - 1.7e-62 211.0 0.0 2.9e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87792.1 - 1e-43 149.7 0.0 1.6e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP87792.1 - 3.2e-24 84.6 71.0 6.3e-05 23.3 0.6 11.4 3 2 9 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP87792.1 - 3.6e-21 74.7 71.3 1.1e-05 25.0 4.2 9.9 2 1 9 12 12 12 10 Leucine rich repeat Homeodomain PF00046.29 PRP87792.1 - 4.5e-15 55.2 4.7 1e-14 54.1 4.7 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP87792.1 - 3e-05 23.8 0.9 7.2e-05 22.6 0.9 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF1616 PF07760.11 PRP87792.1 - 0.017 14.6 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) FTA2 PF13095.6 PRP87792.1 - 0.037 13.6 0.0 0.77 9.3 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Chlam_PMP PF02415.17 PRP87792.1 - 0.048 14.2 3.0 0.37 11.3 0.1 4.0 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat LRR_6 PF13516.6 PRP87792.1 - 0.049 13.7 47.4 2.9 8.2 0.0 13.6 14 0 0 14 14 14 0 Leucine Rich repeat Syndecan PF01034.20 PRP87792.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Pentapeptide_4 PF13599.6 PRP87792.1 - 2 8.6 16.2 5.8 7.1 1.1 7.1 6 3 1 7 7 7 0 Pentapeptide repeats (9 copies) Pkinase PF00069.25 PRP87793.1 - 7.7e-71 238.5 0.1 1.4e-70 237.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87793.1 - 6.9e-34 117.3 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 PRP87793.1 - 1e-27 96.1 0.9 1.5e-13 50.7 0.1 2.8 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_fungal PF17667.1 PRP87793.1 - 1.3e-05 24.2 0.8 4.2e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP87793.1 - 2.9e-05 23.5 0.0 0.00039 19.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PRP87793.1 - 0.0073 15.7 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TcdB_N PF12918.7 PRP87793.1 - 0.078 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain PK PF00224.21 PRP87794.1 - 7.2e-99 331.0 4.9 9.7e-99 330.5 4.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PRP87794.1 - 2.5e-26 92.2 0.4 6.2e-26 90.9 0.1 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain MlrC_C PF07171.12 PRP87794.1 - 0.0032 17.7 1.3 0.0097 16.1 1.3 1.8 1 0 0 1 1 1 1 MlrC C-terminus HpcH_HpaI PF03328.14 PRP87794.1 - 0.0081 15.3 0.2 0.018 14.2 0.2 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GTP_EFTU_D2 PF03144.25 PRP87794.1 - 0.016 15.6 4.7 0.058 13.8 0.3 3.5 2 1 0 2 2 2 0 Elongation factor Tu domain 2 YajC PF02699.15 PRP87794.1 - 0.15 12.0 2.1 8.8 6.3 0.5 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit LCAT PF02450.15 PRP87795.1 - 1.5e-05 24.4 0.0 4.2e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase FHA PF00498.26 PRP87799.1 - 3.9e-13 49.6 0.0 8.4e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain Cbl_N2 PF02761.14 PRP87799.1 - 5.7e-05 23.8 0.4 0.00014 22.5 0.1 1.7 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain Ran-binding PF05508.11 PRP87799.1 - 0.0028 16.7 0.2 0.0041 16.1 0.2 1.2 1 0 0 1 1 1 1 RanGTP-binding protein DUF2457 PF10446.9 PRP87799.1 - 0.0045 16.2 2.7 0.0072 15.5 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Yop-YscD_cpl PF16697.5 PRP87799.1 - 0.0045 17.3 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Met_synt_B12 PF02965.17 PRP87799.1 - 0.077 12.5 0.7 0.19 11.1 0.2 1.7 1 1 1 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain GDC-P PF02347.16 PRP87800.1 - 2.6e-191 636.1 2.4 5.4e-180 598.8 0.1 3.5 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 PRP87800.1 - 9.6e-08 31.4 1.4 3.8e-06 26.1 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 PRP87800.1 - 6.5e-05 22.4 0.0 0.00025 20.4 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase TraI PF07057.11 PRP87800.1 - 0.08 13.1 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 DNA helicase TraI FtsA PF14450.6 PRP87800.1 - 0.17 12.3 0.2 12 6.4 0.0 3.0 2 1 0 2 2 2 0 Cell division protein FtsA CarboxypepD_reg PF13620.6 PRP87801.1 - 5.1e-12 45.9 3.8 9.9e-12 45.0 0.6 2.6 1 1 1 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PRP87801.1 - 3e-08 33.5 0.2 8.4e-08 32.1 0.2 1.8 1 0 0 1 1 1 1 CarboxypepD_reg-like domain Ependymin PF00811.18 PRP87803.1 - 0.0081 16.4 0.6 0.015 15.5 0.6 1.4 1 0 0 1 1 1 1 Ependymin Cpn60_TCP1 PF00118.24 PRP87804.1 - 1e-144 482.8 15.6 1.2e-144 482.6 15.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 PRP87804.1 - 0.023 14.3 4.1 0.044 13.4 0.8 2.7 2 1 0 2 2 2 0 Propionate catabolism activator Homeodomain PF00046.29 PRP87806.1 - 6.8e-18 64.3 2.0 9.6e-18 63.8 2.0 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP87806.1 - 1.4e-07 31.3 1.2 2.3e-07 30.6 0.9 1.6 1 1 0 1 1 1 1 Homeobox KN domain HTH_23 PF13384.6 PRP87806.1 - 0.044 13.6 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain CDP-OH_P_transf PF01066.21 PRP87807.1 - 1.4e-12 48.2 0.8 1.4e-12 48.2 0.8 3.3 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Spore_YhaL PF14147.6 PRP87807.1 - 0.038 13.7 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Sporulation protein YhaL DUF202 PF02656.15 PRP87807.1 - 5.8 7.4 20.8 21 5.6 0.6 4.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Glyco_hydro_3_C PF01915.22 PRP87808.1 - 5.7e-55 186.4 0.0 1.3e-54 185.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Sod_Cu PF00080.20 PRP87808.1 - 4.1e-45 153.4 4.5 1.2e-44 152.0 4.5 1.7 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Glyco_hydro_3 PF00933.21 PRP87808.1 - 6.6e-41 140.7 0.0 1.1e-40 139.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 PRP87808.1 - 2.6e-22 78.7 0.1 5.8e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF5125 PF17163.4 PRP87808.1 - 0.042 14.0 0.1 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5125) Phosphodiest PF01663.22 PRP87809.1 - 3.9e-18 66.2 0.5 1.1e-17 64.7 0.5 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PRP87809.1 - 0.063 12.7 0.1 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 Sulfatase Ank_2 PF12796.7 PRP87810.1 - 4.6e-13 49.6 0.0 2.1e-08 34.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87810.1 - 7.7e-11 42.3 0.6 0.00013 22.5 0.0 4.4 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP87810.1 - 5.3e-09 36.1 3.1 0.5 10.9 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PRP87810.1 - 3.7e-07 30.3 0.0 0.0053 17.0 0.0 4.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87810.1 - 0.0014 18.9 0.0 22 6.0 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat Metal_resist PF13801.6 PRP87810.1 - 0.031 14.5 0.7 9.4 6.4 0.0 2.9 1 1 2 3 3 3 0 Heavy-metal resistance Rhodanese PF00581.20 PRP87811.1 - 1.4e-24 86.6 0.1 8.4e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Aldedh PF00171.22 PRP87812.1 - 2.1e-140 468.3 0.1 2.3e-140 468.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RWP-RK PF02042.15 PRP87813.1 - 1.2e-06 28.4 0.3 3.4e-06 26.9 0.3 1.8 1 0 0 1 1 1 1 RWP-RK domain Acetyltransf_1 PF00583.25 PRP87814.1 - 1.3e-09 38.3 0.1 1.7e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 PRP87814.1 - 4.6e-08 33.8 0.0 6.3e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PRP87814.1 - 1.3e-06 28.4 0.0 3.3e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PRP87814.1 - 0.00018 21.9 0.1 0.00029 21.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PRP87814.1 - 0.00022 21.3 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 PRP87814.1 - 0.00033 20.5 0.0 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 PRP87814.1 - 0.0055 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RE_AccI PF09545.10 PRP87814.1 - 0.076 12.0 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease Rpr2 PF04032.16 PRP87815.1 - 4.4e-24 84.6 0.8 4.4e-24 84.6 0.8 1.5 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain FUR PF01475.19 PRP87815.1 - 0.023 14.8 1.0 0.051 13.7 0.7 1.7 1 1 1 2 2 2 0 Ferric uptake regulator family zf-BED PF02892.15 PRP87815.1 - 0.063 13.3 0.9 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger SNARE PF05739.19 PRP87816.1 - 2.9e-08 33.6 0.2 4.8e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 PRP87816.1 - 0.0004 18.5 0.1 0.00042 18.4 0.1 1.1 1 0 0 1 1 1 1 Prominin DUF2839 PF10999.8 PRP87816.1 - 0.0042 17.4 0.0 0.0088 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2839) Dyp_perox PF04261.12 PRP87816.1 - 0.014 14.4 0.7 0.016 14.2 0.7 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family FadA PF09403.10 PRP87816.1 - 0.021 15.3 0.5 0.027 14.9 0.5 1.1 1 0 0 1 1 1 0 Adhesion protein FadA MCU PF04678.13 PRP87816.1 - 0.021 14.9 0.0 0.027 14.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF2207 PF09972.9 PRP87816.1 - 0.041 12.7 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF745 PF05335.13 PRP87816.1 - 0.046 13.5 0.7 0.057 13.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Prok-TraM PF09228.10 PRP87816.1 - 0.052 13.9 0.1 0.082 13.3 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DUF4407 PF14362.6 PRP87816.1 - 0.1 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 PRP87816.1 - 0.23 11.5 2.2 0.29 11.2 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) EF-hand_12 PF17901.1 PRP87817.1 - 3.4e-30 104.3 4.0 3.4e-30 104.3 4.0 2.8 4 0 0 4 4 4 1 EF-hand fold domain STATa_Ig PF18214.1 PRP87817.1 - 6.1e-21 74.7 0.1 3e-20 72.4 0.1 2.1 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain SH2 PF00017.24 PRP87817.1 - 3.1e-10 40.0 0.1 1.4e-09 37.9 0.1 2.2 2 0 0 2 2 2 1 SH2 domain Dict-STAT-coil PF09267.10 PRP87817.1 - 8.9e-06 26.1 3.9 8.9e-06 26.1 3.9 2.3 2 0 0 2 2 2 1 Dictyostelium STAT, coiled coil Ribosomal_S10 PF00338.22 PRP87817.1 - 0.0048 17.1 0.1 0.03 14.5 0.0 2.2 1 1 1 2 2 2 1 Ribosomal protein S10p/S20e TFIIA PF03153.13 PRP87817.1 - 0.076 13.0 11.8 0.1 12.6 11.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3801 PF12687.7 PRP87817.1 - 0.21 11.7 3.6 0.48 10.5 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PGM_PMM_I PF02878.16 PRP87818.1 - 2.4e-34 118.0 0.0 3.9e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 PRP87818.1 - 9e-28 96.8 0.0 1.6e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 PRP87818.1 - 3.4e-14 53.3 0.0 1e-13 51.8 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 PRP87818.1 - 8.1e-05 22.7 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Peptidase_S64 PF08192.11 PRP87819.1 - 0.028 12.9 5.4 0.031 12.8 5.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 SATase_N PF06426.14 PRP87819.1 - 0.075 13.4 0.5 0.5 10.8 0.1 2.1 1 1 1 2 2 2 0 Serine acetyltransferase, N-terminal AIP3 PF03915.13 PRP87819.1 - 0.094 11.8 5.6 1.4 7.9 5.6 2.0 1 1 0 1 1 1 0 Actin interacting protein 3 DUF2730 PF10805.8 PRP87819.1 - 0.099 12.8 1.0 0.2 11.7 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) SlyX PF04102.12 PRP87819.1 - 0.1 13.3 0.1 0.38 11.4 0.0 2.1 2 0 0 2 2 2 0 SlyX Blo-t-5 PF11642.8 PRP87819.1 - 0.1 12.5 4.8 0.12 12.4 2.2 2.2 1 1 0 2 2 2 0 Mite allergen Blo t 5 CobA_CobO_BtuR PF02572.15 PRP87819.1 - 0.13 12.5 4.9 0.6 10.3 4.9 1.8 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Borrelia_orfA PF02414.15 PRP87819.1 - 0.2 11.2 7.9 0.26 10.9 7.9 1.0 1 0 0 1 1 1 0 Borrelia ORF-A UPF0242 PF06785.11 PRP87819.1 - 1.1 9.3 6.9 1.5 8.9 6.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V-ATPase_G_2 PF16999.5 PRP87819.1 - 3.2 8.2 7.3 0.54 10.7 2.1 2.1 1 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit XPG_I PF00867.18 PRP87821.1 - 2.5e-22 79.0 0.1 6.3e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PRP87821.1 - 3.8e-22 78.7 0.0 8.7e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 PRP87821.1 - 7.5e-05 22.3 0.1 0.00013 21.6 0.1 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 PRP87821.1 - 0.0011 19.6 0.0 0.0027 18.3 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_8 PF13181.6 PRP87821.1 - 0.0073 16.4 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP87821.1 - 0.013 15.5 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP87821.1 - 0.19 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DDOST_48kD PF03345.14 PRP87822.1 - 4.3e-121 404.6 0.0 4.9e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 PRP87822.1 - 0.013 15.9 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) DUF2194 PF09960.9 PRP87822.1 - 0.032 12.6 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) ABC_transp_aux PF09822.9 PRP87822.1 - 0.18 11.2 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Ost5 PF05251.12 PRP87822.1 - 1.6 9.1 5.2 8.2 6.8 0.2 2.5 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Glyco_hydro_99 PF16317.5 PRP87823.1 - 1.4e-124 415.7 2.5 1.7e-124 415.4 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 PRP87823.1 - 0.033 13.6 0.0 0.064 12.7 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase WbsX AP_endonuc_2 PF01261.24 PRP87823.1 - 0.1 12.1 0.0 0.99 8.8 0.0 2.2 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel SurA_N_3 PF13624.6 PRP87824.1 - 0.095 12.5 0.1 0.19 11.5 0.1 1.6 1 1 0 1 1 1 0 SurA N-terminal domain Glyco_hydro_38N PF01074.22 PRP87825.1 - 1.6e-52 178.7 5.7 2.9e-52 177.9 5.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 PRP87825.1 - 6.4e-13 48.7 0.6 1.7e-12 47.3 0.6 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 PRP87825.1 - 1.4e-10 41.6 0.0 4.6e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 PRP87825.1 - 1.7e-09 37.6 0.1 4.1e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Methyltransf_32 PF13679.6 PRP87826.1 - 7.8e-05 22.7 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_anti-codon PF01336.25 PRP87826.1 - 0.0012 18.8 0.0 0.0038 17.2 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_1 PF00133.22 PRP87827.1 - 1.9e-61 208.1 3.1 7e-40 136.9 2.9 6.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 PRP87827.1 - 1.9e-51 174.2 0.0 4.4e-51 173.0 0.0 1.6 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 PRP87827.1 - 8.9e-26 90.5 0.0 4.7e-19 68.4 0.0 3.9 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PRP87827.1 - 4.7e-07 29.9 0.0 1e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PRP87827.1 - 0.01 15.2 0.0 1.7 7.9 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pro-kuma_activ PF09286.11 PRP87828.1 - 1.9e-22 80.1 0.0 2.8e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP87828.1 - 1.1e-07 31.4 0.1 1.8e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Subtilase family LRR_9 PF14580.6 PRP87831.1 - 9.4e-23 80.6 17.7 2e-10 40.5 1.9 4.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 PRP87831.1 - 3.5e-22 78.1 32.0 1.8e-06 28.2 2.7 5.7 2 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP87831.1 - 4.1e-18 64.9 29.9 2.9e-06 27.0 3.9 5.1 3 1 0 4 4 4 4 Leucine rich repeat LRR_6 PF13516.6 PRP87831.1 - 0.81 9.9 22.8 4.1 7.7 0.1 7.3 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 PRP87831.1 - 0.87 10.4 18.8 43 5.2 0.1 6.8 6 2 0 6 6 6 0 Leucine Rich Repeat Ank_2 PF12796.7 PRP87832.1 - 5.5e-104 340.9 9.0 3.7e-18 65.9 2.1 11.4 3 3 7 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87832.1 - 6.7e-82 268.9 11.1 9.9e-09 35.6 0.0 14.6 8 4 6 15 15 15 13 Ankyrin repeats (many copies) Ank PF00023.30 PRP87832.1 - 4.5e-76 248.2 23.4 7.6e-05 23.0 0.0 20.0 21 0 0 21 21 21 17 Ankyrin repeat Ank_3 PF13606.6 PRP87832.1 - 2.2e-74 236.5 8.7 0.00065 20.0 0.0 19.4 20 0 0 20 20 20 16 Ankyrin repeat Ank_5 PF13857.6 PRP87832.1 - 1.8e-72 238.4 11.4 1.6e-07 31.5 0.0 15.8 7 4 10 17 17 17 14 Ankyrin repeats (many copies) AnkUBD PF18418.1 PRP87832.1 - 0.086 13.0 0.0 1.1 9.5 0.0 2.9 2 2 1 3 3 3 0 Ankyrin ubiquitin-binding domain ABC2_membrane PF01061.24 PRP87833.1 - 1.4e-38 132.4 24.7 2e-38 131.9 24.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PRP87833.1 - 1.3e-26 93.7 3.8 2.4e-26 92.9 0.1 2.7 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 PRP87833.1 - 4.7e-05 23.3 0.1 0.00013 21.9 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 PRP87833.1 - 0.00063 19.6 1.0 0.36 10.6 0.1 2.7 2 1 1 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 PRP87833.1 - 0.00096 19.7 3.7 0.009 16.6 0.1 2.7 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 PRP87833.1 - 0.0021 18.3 2.4 0.0091 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP87833.1 - 0.0047 17.3 1.4 0.012 16.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 PRP87833.1 - 0.007 16.6 1.2 0.012 15.9 0.0 2.0 2 1 1 3 3 1 1 AAA domain ATPase_2 PF01637.18 PRP87833.1 - 0.016 15.2 0.2 0.046 13.6 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 PRP87833.1 - 0.02 15.3 1.1 0.067 13.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PRP87833.1 - 0.024 14.6 0.1 0.083 12.8 0.0 1.9 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_30 PF13604.6 PRP87833.1 - 0.028 14.1 0.3 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PRP87833.1 - 0.031 13.9 1.6 0.078 12.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PRP87833.1 - 0.034 14.5 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 PRP87833.1 - 0.035 13.8 0.1 0.081 12.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 PRP87833.1 - 0.05 12.8 2.5 0.094 11.9 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 PRP87833.1 - 0.057 13.5 0.2 0.2 11.7 0.2 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 PRP87833.1 - 0.076 13.2 0.2 0.25 11.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 PRP87833.1 - 0.086 12.8 0.9 0.22 11.4 0.1 2.2 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 PRP87833.1 - 0.1 12.2 0.1 0.25 10.9 0.1 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 PRP87833.1 - 0.1 12.5 0.9 0.27 11.2 0.2 2.0 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 PRP87833.1 - 0.15 12.6 0.0 0.15 12.6 0.0 2.9 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 PRP87833.1 - 0.22 11.2 2.7 0.55 9.9 0.1 2.6 3 0 0 3 3 3 0 AAA domain PSD4 PF07631.11 PRP87833.1 - 0.39 11.3 3.6 14 6.3 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1592) ATP_bind_1 PF03029.17 PRP87833.1 - 0.85 9.4 4.3 0.98 9.1 0.1 2.6 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 PRP87833.1 - 1.2 9.1 5.6 0.62 10.1 0.2 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain FliT PF05400.13 PRP87833.1 - 1.3 9.9 11.6 0.041 14.7 2.9 2.6 2 0 0 2 2 2 0 Flagellar protein FliT PTPS PF01242.19 PRP87835.1 - 2.7e-35 121.0 0.7 6.2e-35 119.8 0.7 1.7 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase RNase_H PF00075.24 PRP87835.1 - 0.0075 16.5 0.2 0.03 14.5 0.2 2.1 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 PRP87835.1 - 0.035 14.8 0.4 0.16 12.7 0.4 2.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Arf PF00025.21 PRP87836.1 - 0.15 11.5 0.2 0.21 11.0 0.2 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family LRR_6 PF13516.6 PRP87838.1 - 2.1e-19 67.8 51.0 0.00021 21.1 0.1 16.1 17 0 0 17 17 17 9 Leucine Rich repeat LRR_4 PF12799.7 PRP87838.1 - 0.069 13.6 53.5 0.18 12.3 0.6 10.1 4 4 4 9 9 9 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP87838.1 - 0.096 13.3 28.9 33 5.6 0.0 11.0 13 0 0 13 13 13 0 Leucine Rich Repeat GTP_EFTU PF00009.27 PRP87839.1 - 0.00013 21.5 0.0 0.00097 18.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Biliv-reduc_cat PF09166.10 PRP87840.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Biliverdin reductase, catalytic LRR_6 PF13516.6 PRP87841.1 - 2.7e-09 36.3 2.2 0.00017 21.4 0.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.7 PRP87841.1 - 0.015 15.7 2.3 0.13 12.7 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) VGLL4 PF15245.6 PRP87841.1 - 0.37 10.8 2.9 0.28 11.2 0.7 1.8 1 1 1 2 2 2 0 Transcription cofactor vestigial-like protein 4 ADIP PF11559.8 PRP87844.1 - 1.1e-18 67.8 62.8 6.3e-16 58.8 24.1 4.7 4 1 1 5 5 5 3 Afadin- and alpha -actinin-Binding Cnl2_NKP2 PF09447.10 PRP87844.1 - 0.0039 17.3 1.5 3.9 7.7 0.1 3.3 2 0 0 2 2 2 2 Cnl2/NKP2 family protein DUF1691 PF07950.11 PRP87846.1 - 0.17 12.6 0.2 0.25 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) LCAT PF02450.15 PRP87848.1 - 2.2e-05 23.8 0.1 0.012 14.9 0.0 2.5 2 2 0 2 2 2 2 Lecithin:cholesterol acyltransferase Type2_restr_D3 PF16902.5 PRP87849.1 - 0.057 13.3 0.3 0.072 13.0 0.3 1.3 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain EF-hand_7 PF13499.6 PRP87852.1 - 4.4e-21 75.1 3.3 9.2e-10 38.8 0.9 3.6 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 PRP87852.1 - 1.4e-17 61.9 6.2 0.0015 17.9 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PRP87852.1 - 2e-15 55.3 7.4 0.002 17.9 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PRP87852.1 - 5.3e-11 41.5 11.9 0.017 14.6 0.1 5.2 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 PRP87852.1 - 2.3e-09 36.9 3.6 0.017 14.9 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP87852.1 - 0.00025 21.4 0.6 0.23 11.8 0.0 3.0 1 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 PRP87852.1 - 0.071 13.1 0.1 1.1 9.3 0.1 2.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Pkinase_Tyr PF07714.17 PRP87853.1 - 1.3e-55 188.5 0.1 2.3e-55 187.7 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87853.1 - 5.1e-36 124.4 0.1 9.7e-36 123.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP87853.1 - 1.2e-05 25.7 5.4 2.5e-05 24.7 5.4 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Kinase-like PF14531.6 PRP87853.1 - 3.9e-05 23.1 0.0 8.8e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PRP87853.1 - 0.0026 17.4 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family SKG6 PF08693.10 PRP87853.1 - 0.081 12.3 1.5 0.17 11.3 1.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PRP87853.1 - 0.087 13.7 0.1 0.37 11.7 0.1 2.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CAP PF00188.26 PRP87856.1 - 2.3e-18 67.2 4.3 2.3e-18 67.2 4.3 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 PRP87856.1 - 3.9e-09 36.3 4.9 1.2e-08 34.7 4.9 1.9 1 0 0 1 1 1 1 PAN domain B_lectin PF01453.24 PRP87856.1 - 3.6e-06 27.4 0.8 0.0017 18.9 0.1 2.8 2 1 1 3 3 3 2 D-mannose binding lectin PAN_3 PF08277.12 PRP87856.1 - 0.0087 15.8 2.6 0.0087 15.8 2.6 2.2 2 0 0 2 2 2 1 PAN-like domain PAN_1 PF00024.26 PRP87856.1 - 0.016 15.2 4.7 0.041 13.8 4.7 1.7 1 0 0 1 1 1 0 PAN domain PAN_2 PF08276.11 PRP87856.1 - 0.027 14.6 6.2 0.09 12.9 6.2 1.8 1 0 0 1 1 1 0 PAN-like domain AbrB-like PF14250.6 PRP87856.1 - 0.1 12.7 0.3 2.9 8.1 0.0 2.8 2 1 1 3 3 3 0 AbrB-like transcriptional regulator Pirin PF02678.16 PRP87857.1 - 2.3e-31 108.0 4.6 1e-29 102.6 3.8 2.9 2 1 0 2 2 2 1 Pirin Pirin_C PF05726.13 PRP87857.1 - 2.1e-29 101.9 0.2 1.9e-27 95.6 0.0 2.9 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 PRP87857.1 - 0.005 16.5 2.9 0.53 10.0 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Glyco_hydro_14 PF01373.17 PRP87859.1 - 6.1e-105 351.4 1.2 7e-105 351.3 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 PRP87859.1 - 0.0089 15.7 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 SKA1 PF07160.12 PRP87860.1 - 0.062 13.1 0.0 0.062 13.1 0.0 2.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 HSP20 PF00011.21 PRP87861.1 - 6.8e-22 77.5 1.5 1.3e-21 76.7 1.5 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP87861.1 - 7.6e-09 35.0 0.0 1.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA SH2 PF00017.24 PRP87861.1 - 4.1e-07 30.0 0.0 1.1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 SH2 domain BON PF04972.17 PRP87861.1 - 0.00029 21.1 1.1 0.0012 19.1 0.1 2.4 3 0 0 3 3 3 1 BON domain PAP_fibrillin PF04755.12 PRP87861.1 - 0.065 13.2 0.0 0.73 9.7 0.0 2.5 3 0 0 3 3 3 0 PAP_fibrillin DUF1411 PF07199.11 PRP87861.1 - 0.35 10.5 1.4 0.71 9.5 0.4 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1411) DUF4097 PF13349.6 PRP87861.1 - 0.6 9.4 3.8 2.2 7.5 3.9 2.0 1 1 0 1 1 1 0 Putative adhesin CENP-X PF09415.10 PRP87862.1 - 2.2e-12 47.1 1.1 3e-11 43.5 0.1 2.6 2 1 0 2 2 2 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 PRP87862.1 - 1.3e-05 25.4 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 PRP87862.1 - 0.075 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region CAP_N PF01213.19 PRP87863.1 - 3.3 7.1 8.8 5.1 6.5 8.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ank_2 PF12796.7 PRP87864.1 - 3.3e-28 98.1 6.6 5e-08 33.4 0.0 7.4 5 3 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP87864.1 - 2.2e-21 75.9 0.7 6.8e-05 23.3 0.0 6.6 5 1 1 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87864.1 - 1.3e-16 59.0 0.0 0.68 10.7 0.1 8.7 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 PRP87864.1 - 2.6e-11 43.4 2.1 0.047 14.2 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 PRP87864.1 - 7.7e-11 42.0 0.0 0.033 14.5 0.0 6.5 6 1 1 7 7 7 3 Ankyrin repeats (many copies) WWE PF02825.20 PRP87864.1 - 0.00034 21.1 3.7 0.0014 19.2 3.7 2.2 1 0 0 1 1 1 1 WWE domain FAM86 PF14904.6 PRP87864.1 - 0.069 13.2 0.1 0.82 9.8 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function CRAL_TRIO PF00650.20 PRP87865.1 - 3.6e-34 117.8 0.0 4.7e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PRP87865.1 - 0.0045 17.2 0.0 0.0065 16.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SpoIIIAH PF12685.7 PRP87866.1 - 0.0026 17.6 2.1 0.0037 17.1 2.1 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF913 PF06025.12 PRP87866.1 - 0.025 13.6 3.3 0.037 13.0 3.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.6 PRP87866.1 - 0.049 13.8 6.0 0.088 13.0 6.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 PRP87866.1 - 0.094 10.9 26.5 0.12 10.5 26.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4820 PF16091.5 PRP87866.1 - 0.096 12.0 2.6 0.19 11.1 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Paf1 PF03985.13 PRP87866.1 - 0.13 11.2 25.8 0.21 10.6 25.8 1.2 1 0 0 1 1 1 0 Paf1 RNA_polI_A34 PF08208.11 PRP87866.1 - 0.16 12.1 9.6 0.26 11.3 9.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SDA1 PF05285.12 PRP87866.1 - 0.25 10.8 25.9 0.36 10.2 25.9 1.1 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 PRP87866.1 - 0.3 8.8 6.5 0.43 8.3 6.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit LRR_4 PF12799.7 PRP87866.1 - 0.45 11.0 17.1 12 6.5 0.2 5.9 3 1 3 6 6 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP87866.1 - 0.53 10.5 3.4 43 4.5 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat DNA_pol_phi PF04931.13 PRP87866.1 - 0.58 8.2 35.2 0.83 7.7 35.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi SpoIIP PF07454.11 PRP87866.1 - 0.64 9.4 9.7 0.92 8.9 9.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NOA36 PF06524.12 PRP87866.1 - 0.65 9.3 22.2 1.3 8.3 22.2 1.5 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 PRP87866.1 - 0.97 8.6 16.4 1.5 8.0 16.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Connexin PF00029.19 PRP87866.1 - 1.2 8.9 7.7 2.1 8.1 7.7 1.3 1 0 0 1 1 1 0 Connexin DUF3391 PF11871.8 PRP87866.1 - 1.4 9.5 8.9 3.5 8.2 8.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) CDC45 PF02724.14 PRP87866.1 - 2.5 6.3 22.2 3.7 5.7 22.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 PRP87866.1 - 5.9 5.5 8.8 8.4 5.0 8.8 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 PRP87866.1 - 6 7.3 10.5 12 6.3 10.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPA43_OB PF17875.1 PRP87866.1 - 6.5 7.4 11.2 14 6.3 11.2 1.5 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I TFIIA PF03153.13 PRP87866.1 - 8.2 6.3 15.9 12 5.8 15.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 PRP87866.1 - 8.5 5.7 29.8 14 4.9 29.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 PRP87866.1 - 8.7 5.0 13.0 13 4.4 13.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FSA_C PF10479.9 PRP87867.1 - 0.079 11.1 0.1 0.13 10.4 0.1 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus GrpE PF01025.19 PRP87867.1 - 0.18 11.5 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 GrpE PPR_2 PF13041.6 PRP87869.1 - 1.2e-10 41.4 5.9 3.8e-06 27.0 0.0 5.7 5 2 2 7 7 7 2 PPR repeat family PPR PF01535.20 PRP87869.1 - 2.7e-09 36.7 0.6 0.18 12.1 0.0 5.4 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.6 PRP87869.1 - 3.3e-07 30.3 0.0 1.1e-05 25.4 0.0 3.8 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 PRP87869.1 - 9.6e-05 22.0 0.0 0.36 10.6 0.0 4.3 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 PRP87869.1 - 0.012 15.0 0.0 0.093 12.1 0.0 2.4 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 PRP87869.1 - 0.098 12.5 0.1 2.2 8.1 0.0 2.8 2 1 0 2 2 2 0 Mitochondrial ATPase expression Pkinase PF00069.25 PRP87870.1 - 9.7e-49 166.1 0.0 1.1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87870.1 - 1.2e-21 77.2 0.0 1.5e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP87870.1 - 2.5e-06 27.1 0.0 3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP87870.1 - 7.1e-05 22.3 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP87870.1 - 0.0039 17.1 0.0 0.018 15.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 PRP87870.1 - 0.037 13.7 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PRP87870.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Aminotran_1_2 PF00155.21 PRP87872.1 - 2.6e-90 303.2 0.0 3.1e-90 303.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_6 PF12697.7 PRP87873.1 - 4.2e-17 63.5 0.9 6.2e-17 62.9 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP87873.1 - 3.1e-09 36.5 0.1 4.3e-09 36.0 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP87873.1 - 8.7e-08 32.1 2.4 0.00026 20.7 2.2 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 PRP87873.1 - 0.0066 16.6 0.5 1.6 8.8 0.0 2.7 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_5 PF12695.7 PRP87873.1 - 0.0092 15.8 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 PRP87873.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 PRP87873.1 - 0.14 11.9 0.3 0.38 10.4 0.1 1.7 2 0 0 2 2 2 0 PGAP1-like protein Ras PF00071.22 PRP87876.1 - 2.3e-58 196.4 0.2 3.1e-58 195.9 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP87876.1 - 5.8e-32 110.4 0.1 1.1e-31 109.6 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TRAM_LAG1_CLN8 PF03798.16 PRP87876.1 - 2.2e-23 83.1 19.3 3.6e-23 82.3 19.3 1.3 1 0 0 1 1 1 1 TLC domain Arf PF00025.21 PRP87876.1 - 1.2e-12 47.7 0.1 1.7e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP87876.1 - 2e-06 27.8 0.0 3.5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP87876.1 - 0.00017 21.0 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PRP87876.1 - 0.00047 20.1 0.0 0.0049 16.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PRP87876.1 - 0.0011 18.5 0.0 0.021 14.4 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 PRP87876.1 - 0.013 15.0 0.1 0.043 13.4 0.0 1.7 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 PRP87876.1 - 0.015 14.8 0.2 0.025 14.1 0.2 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 PRP87876.1 - 0.018 14.4 0.2 0.076 12.3 0.1 2.0 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 PRP87876.1 - 0.039 13.7 0.1 0.42 10.3 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PRP87876.1 - 0.039 14.2 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PRP87876.1 - 0.056 13.8 0.0 0.15 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 PRP87876.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 PRP87876.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 PRP87876.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NTPase SRPRB PF09439.10 PRP87876.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PRP87876.1 - 0.13 11.4 0.8 0.42 9.7 0.2 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 PRP87876.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Carb_bind PF10645.9 PRP87877.1 - 5.6e-08 32.9 33.4 4.4e-05 23.6 4.7 12.2 10 6 2 13 13 13 4 Carbohydrate binding VPS9 PF02204.18 PRP87878.1 - 1.8e-20 73.1 0.4 4.4e-20 71.8 0.4 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain FERM_M PF00373.18 PRP87878.1 - 1.4e-08 35.2 0.1 6.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 FERM central domain zf-RING_UBOX PF13445.6 PRP87878.1 - 4.9e-07 29.7 1.1 1.9e-06 27.8 0.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-TRAF PF02176.18 PRP87878.1 - 4.4e-06 27.3 23.6 0.00043 20.9 2.6 4.0 2 1 2 4 4 4 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 PRP87878.1 - 7.6e-05 22.5 1.6 7.6e-05 22.5 1.6 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP87878.1 - 9.8e-05 22.4 1.9 9.8e-05 22.4 1.9 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 PRP87878.1 - 0.0004 20.2 0.3 0.0019 18.0 0.3 2.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP87878.1 - 0.012 15.6 0.2 0.012 15.6 0.2 2.7 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PRP87878.1 - 0.013 15.3 1.3 0.013 15.3 1.3 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) GRAM PF02893.20 PRP87878.1 - 0.016 15.0 0.0 0.044 13.7 0.0 1.8 1 0 0 1 1 1 0 GRAM domain FAD_oxidored PF12831.7 PRP87879.1 - 4.8e-107 359.0 0.0 5.9e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PRP87879.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Peptidase_M14 PF00246.24 PRP87882.1 - 3.4e-66 224.0 0.4 4.7e-66 223.5 0.4 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase TMEM144 PF07857.12 PRP87882.1 - 3.9e-21 75.4 15.6 3.9e-21 75.4 15.6 1.5 2 0 0 2 2 2 1 Transmembrane family, TMEM144 of transporters CarboxypepD_reg PF13620.6 PRP87882.1 - 2.5e-09 37.3 0.8 5.1e-09 36.3 0.8 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Sugar_transport PF06800.12 PRP87882.1 - 2.4e-08 33.6 18.8 1.1e-06 28.2 7.9 2.4 2 0 0 2 2 2 2 Sugar transport protein AstE_AspA PF04952.14 PRP87882.1 - 1e-05 24.8 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 PRP87882.1 - 0.00046 19.7 0.2 0.00092 18.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) PEGA PF08308.11 PRP87882.1 - 0.0043 16.9 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 PEGA domain CarbopepD_reg_2 PF13715.6 PRP87882.1 - 0.041 13.9 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 CarboxypepD_reg-like domain UPF0060 PF02694.15 PRP87882.1 - 2.1 8.6 18.7 0.05 13.8 9.2 3.1 3 1 1 4 4 4 0 Uncharacterised BCR, YnfA/UPF0060 family DnaJ_C PF01556.18 PRP87883.1 - 3.7e-43 147.2 0.7 5.9e-43 146.5 0.7 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PRP87883.1 - 7e-26 90.1 4.7 1.4e-25 89.2 4.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PRP87883.1 - 5.4e-16 58.7 22.1 1.2e-15 57.6 22.1 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PRP87883.1 - 4.1e-05 23.5 12.1 0.00052 19.9 1.6 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 PRP87883.1 - 0.0003 20.8 9.0 0.031 14.3 2.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Gp-FAR-1 PF05823.12 PRP87883.1 - 0.0042 17.4 0.5 0.0096 16.3 0.5 1.5 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) zinc_ribbon_6 PF14599.6 PRP87883.1 - 0.5 10.4 7.9 3.9 7.6 0.8 2.8 2 0 0 2 2 2 0 Zinc-ribbon TackOD1 PF18551.1 PRP87883.1 - 0.61 9.7 8.5 0.4 10.3 0.9 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-RING_10 PF16685.5 PRP87883.1 - 0.95 9.6 10.9 0.088 12.9 1.3 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 PRP87883.1 - 3.9 7.5 12.5 2.2 8.3 3.8 2.4 2 0 0 2 2 2 0 zinc-RING finger domain DUF4770 PF15994.5 PRP87883.1 - 5.9 7.1 8.8 0.44 10.8 3.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) RasGEF PF00617.19 PRP87886.1 - 7e-40 137.1 1.4 2.3e-39 135.4 1.4 2.0 1 0 0 1 1 1 1 RasGEF domain LRR_8 PF13855.6 PRP87886.1 - 1.4e-25 88.8 31.2 2.7e-08 33.5 0.2 5.9 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PRP87886.1 - 7.2e-22 77.1 35.7 2.4e-05 24.6 0.0 7.7 3 1 7 10 10 10 9 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 PRP87886.1 - 8.1e-14 51.7 2.4 1.3e-13 51.1 0.6 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif LRR_1 PF00560.33 PRP87886.1 - 5.8e-09 35.3 31.7 1.3 9.8 0.0 9.8 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP87886.1 - 5.3e-06 26.1 28.0 1.1 9.4 0.0 8.8 9 0 0 9 9 9 3 Leucine Rich repeat Drf_FH3 PF06367.16 PRP87886.1 - 0.0001 22.0 0.1 0.00038 20.1 0.1 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 PRP87886.1 - 0.0014 18.2 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain LRR_9 PF14580.6 PRP87886.1 - 0.15 11.6 10.2 0.27 10.7 0.4 3.2 1 1 1 3 3 3 0 Leucine-rich repeat Pkinase PF00069.25 PRP87887.1 - 2.8e-60 203.9 0.0 3.4e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87887.1 - 5.6e-15 55.3 0.0 7.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP87887.1 - 1.3e-08 35.1 0.0 8.4e-07 29.1 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 PRP87887.1 - 0.093 12.3 0.0 0.18 11.4 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 PRP87887.1 - 0.17 10.6 0.0 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Phlebovirus_G2 PF07245.11 PRP87888.1 - 0.0045 15.5 0.2 0.008 14.7 0.2 1.3 1 0 0 1 1 1 1 Phlebovirus glycoprotein G2 Amnionless PF14828.6 PRP87888.1 - 0.005 15.7 0.1 0.0093 14.8 0.1 1.4 1 0 0 1 1 1 1 Amnionless Colicin_D PF11429.8 PRP87888.1 - 0.016 15.6 0.1 0.049 14.1 0.1 1.8 1 0 0 1 1 1 0 Colicin D DUF3079 PF11278.8 PRP87888.1 - 0.18 11.7 1.7 9.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) TFIIB PF00382.19 PRP87889.1 - 2.2e-08 34.0 0.1 0.0036 17.3 0.0 3.1 3 0 0 3 3 3 2 Transcription factor TFIIB repeat DUF4059 PF13268.6 PRP87890.1 - 0.051 14.0 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) Pkinase PF00069.25 PRP87891.1 - 0.0029 17.0 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP87891.1 - 0.019 13.8 0.0 0.027 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 PRP87891.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH_6_hur PF04655.14 PRP87891.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Kdo PF06293.14 PRP87891.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_A_exo1 PF01612.20 PRP87893.1 - 8e-34 116.9 0.9 4e-33 114.6 0.9 2.0 1 1 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 PRP87893.1 - 1.7e-14 54.3 0.0 1.4e-13 51.4 0.0 2.6 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 PRP87893.1 - 5.7e-14 51.8 0.0 1.8e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 HRDC domain DcpS_C PF11969.8 PRP87894.1 - 1.4e-26 93.2 2.6 3e-26 92.1 2.6 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding FHA_2 PF17913.1 PRP87894.1 - 3.8e-15 55.9 0.1 9.3e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 PRP87894.1 - 1.8e-10 40.6 1.8 5.9e-10 39.0 1.8 1.9 1 0 0 1 1 1 1 PBZ domain HIT PF01230.23 PRP87894.1 - 3.4e-10 40.5 0.6 1.2e-09 38.8 0.4 2.1 2 0 0 2 2 1 1 HIT domain BRCT PF00533.26 PRP87894.1 - 2.5e-09 37.4 0.0 1.2e-08 35.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Macro PF01661.21 PRP87894.1 - 7.2e-08 32.5 0.2 0.0077 16.3 0.0 3.2 2 1 1 3 3 3 2 Macro domain BRCT_2 PF16589.5 PRP87894.1 - 1.4e-07 31.8 0.0 4.3e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PRP87894.1 - 2.1e-06 27.6 0.1 7.3e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 twin BRCT domain FHA PF00498.26 PRP87894.1 - 0.0011 19.2 0.5 0.0028 18.0 0.5 1.7 1 0 0 1 1 1 1 FHA domain zf-C2HE PF16278.5 PRP87894.1 - 0.0036 17.7 0.1 0.0036 17.7 0.1 2.6 2 0 0 2 2 1 1 C2HE / C2H2 / C2HC zinc-binding finger DDE_Tnp_1_6 PF13751.6 PRP87894.1 - 0.79 10.0 6.8 0.11 12.7 1.2 2.4 2 0 0 2 2 2 0 Transposase DDE domain CRISPR_Cas9_WED PF18061.1 PRP87895.1 - 0.019 15.0 1.7 0.26 11.4 0.2 2.2 1 1 1 2 2 2 0 CRISPR-Cas9 WED domain TCP PF03634.13 PRP87895.1 - 0.04 14.5 0.2 0.24 11.9 0.2 2.0 1 1 0 1 1 1 0 TCP family transcription factor C8 PF08742.11 PRP87895.1 - 0.54 10.7 4.0 1.3 9.5 0.2 2.7 2 1 1 3 3 3 0 C8 domain rve PF00665.26 PRP87896.1 - 9.9e-22 77.4 0.0 1.5e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 PRP87897.1 - 2.4e-14 53.5 0.1 3.2e-12 46.7 0.0 3.0 2 1 1 3 3 3 1 Integrase core domain Hox9_act PF04617.13 PRP87897.1 - 0.00011 23.0 0.0 0.33 11.7 0.0 2.1 2 0 0 2 2 2 2 Hox9 activation region DUF3275 PF11679.8 PRP87897.1 - 0.0075 16.3 0.2 4.5 7.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3275) SF3A2 PF16835.5 PRP87897.1 - 0.054 13.9 0.1 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) rve_3 PF13683.6 PRP87897.1 - 0.065 13.0 0.1 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain NCE101 PF11654.8 PRP87897.1 - 0.072 12.8 1.7 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Non-classical export protein 1 Foie-gras_1 PF11817.8 PRP87897.1 - 0.15 11.6 0.9 5.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Foie gras liver health family 1 Flp_N PF03930.14 PRP87898.1 - 0.013 15.5 1.2 0.19 11.7 0.2 2.6 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus DUF4286 PF14114.6 PRP87898.1 - 0.016 15.7 0.3 0.17 12.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Chromo PF00385.24 PRP87901.1 - 1.8e-12 47.0 0.0 3.2e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PRP87901.1 - 0.11 12.7 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 adh_short PF00106.25 PRP87902.1 - 4.8e-19 68.6 0.0 2.1e-17 63.2 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP87902.1 - 6.2e-11 42.3 0.0 9.3e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP87902.1 - 2.5e-09 37.3 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PRP87902.1 - 0.0045 16.2 0.2 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 PRP87902.1 - 0.0054 16.2 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase_Tyr PF07714.17 PRP87903.1 - 4e-72 242.6 0.0 6.1e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP87903.1 - 4.1e-59 196.2 74.4 2.1e-11 43.4 0.3 14.7 8 4 8 16 16 16 14 Leucine rich repeat Pkinase PF00069.25 PRP87903.1 - 8.7e-49 166.2 0.0 1.3e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP87903.1 - 1.6e-43 145.9 82.5 1.9e-05 24.9 0.1 19.2 15 5 5 20 20 19 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP87903.1 - 4.6e-16 56.9 58.0 2.4 9.0 0.1 22.8 22 3 0 22 22 21 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP87903.1 - 3e-11 42.4 63.9 1.4 9.2 0.0 21.0 23 0 0 23 23 23 5 Leucine Rich repeat Rax2 PF12768.7 PRP87903.1 - 0.0065 15.9 0.1 0.03 13.8 0.1 2.2 1 1 0 1 1 1 1 Cortical protein marker for cell polarity Pkinase_fungal PF17667.1 PRP87903.1 - 0.018 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PRP87903.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CcmD PF04995.14 PRP87903.1 - 0.2 11.7 0.2 0.45 10.6 0.2 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) EphA2_TM PF14575.6 PRP87903.1 - 0.25 12.2 0.7 0.47 11.4 0.7 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Cpn60_TCP1 PF00118.24 PRP87904.1 - 3.7e-154 514.0 14.8 4.3e-154 513.8 14.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Stk19 PF10494.9 PRP87905.1 - 2.6e-33 115.7 0.0 4.6e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DEAD PF00270.29 PRP87906.1 - 1.8e-30 106.0 0.5 8.7e-30 103.8 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP87906.1 - 4.8e-23 81.6 0.3 2.1e-22 79.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP87906.1 - 2.4e-08 34.2 0.0 6.6e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PRP87906.1 - 0.0017 18.1 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 PRP87906.1 - 0.0088 15.9 0.1 0.049 13.5 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.6 PRP87906.1 - 0.0093 16.3 0.3 0.018 15.4 0.1 1.9 2 1 0 2 2 2 1 AAA domain DUF1611 PF07755.11 PRP87906.1 - 0.1 11.9 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Glyco_transf_4 PF13439.6 PRP87906.1 - 0.22 11.5 0.0 0.53 10.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Pkinase PF00069.25 PRP87907.1 - 8.6e-37 126.9 0.0 6.4e-36 124.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87907.1 - 1.5e-27 96.5 0.0 3.1e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP87907.1 - 3.7e-08 32.6 0.0 3.7e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase OmpH PF03938.14 PRP87907.1 - 0.012 15.9 8.5 0.027 14.8 8.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Kdo PF06293.14 PRP87907.1 - 0.019 14.3 0.2 0.044 13.1 0.2 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ureide_permease PF07168.11 PRP87907.1 - 0.071 11.8 1.9 0.38 9.4 1.1 2.1 2 0 0 2 2 2 0 Ureide permease APH PF01636.23 PRP87907.1 - 0.073 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4200 PF13863.6 PRP87907.1 - 0.15 12.5 16.1 0.45 10.9 16.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) YMF19 PF02326.15 PRP87907.1 - 1.1 10.1 4.0 1.9 9.4 1.5 2.7 2 1 0 2 2 2 0 Plant ATP synthase F0 Exonuc_VII_L PF02601.15 PRP87907.1 - 2 7.9 7.6 0.57 9.7 4.4 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit Streptin-Immun PF11083.8 PRP87908.1 - 0.083 13.3 0.5 0.083 13.3 0.5 2.8 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein Prominin PF05478.11 PRP87908.1 - 1.1 7.1 17.6 1.9 6.4 17.6 1.4 1 0 0 1 1 1 0 Prominin DUF1722 PF08349.11 PRP87908.1 - 2 8.7 7.4 3 8.2 2.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) Spore_III_AB PF09548.10 PRP87908.1 - 3 7.9 6.2 2 8.5 0.7 2.7 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CCDC-167 PF15188.6 PRP87908.1 - 4.1 7.8 12.0 0.4 11.0 1.3 3.1 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Baculo_PEP_C PF04513.12 PRP87908.1 - 4.3 7.4 22.8 0.67 10.0 5.4 3.0 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ERCC3_RAD25_C PF16203.5 PRP87909.1 - 5.2e-110 366.5 0.0 5.2e-110 366.5 0.0 2.0 2 0 0 2 2 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 PRP87909.1 - 3.7e-34 117.6 0.0 6e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP87909.1 - 1.8e-19 70.4 1.4 1.9e-18 67.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP87909.1 - 2.3e-12 47.3 0.0 1e-11 45.2 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 PRP87909.1 - 4.4e-07 28.9 0.1 6e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 PRP87909.1 - 0.00059 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SR-25 PF10500.9 PRP87909.1 - 0.0093 15.6 13.0 0.021 14.4 13.0 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PDCD2_C PF04194.13 PRP87909.1 - 0.015 15.4 3.4 0.045 13.8 3.4 1.8 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain RPN2_C PF18004.1 PRP87909.1 - 0.051 13.5 12.4 0.061 13.3 10.9 1.9 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain F-protein PF00469.20 PRP87909.1 - 0.055 13.1 5.8 0.13 11.9 5.8 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef AP3D1 PF06375.11 PRP87909.1 - 0.26 11.5 16.4 0.63 10.3 16.4 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 NARP1 PF12569.8 PRP87909.1 - 0.49 9.2 12.8 0.78 8.6 12.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.12 PRP87909.1 - 1 9.6 8.3 1.9 8.7 8.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family HA2 PF04408.23 PRP87909.1 - 1.4 9.2 5.5 2.8 8.3 4.2 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) Rtf2 PF04641.12 PRP87909.1 - 1.5 8.1 13.5 2.8 7.2 13.5 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger CPSF100_C PF13299.6 PRP87909.1 - 2.8 8.1 8.4 1.8 8.7 6.2 1.9 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal Med19 PF10278.9 PRP87909.1 - 3.3 7.6 18.1 7.7 6.4 17.7 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Pox_Ag35 PF03286.14 PRP87909.1 - 5.6 6.7 16.2 12 5.7 16.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM60A PF15396.6 PRP87909.1 - 6.4 6.7 14.7 13 5.7 14.7 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Eapp_C PF10238.9 PRP87909.1 - 8.9 6.4 9.6 17 5.5 8.3 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein WD40 PF00400.32 PRP87910.1 - 1.4e-29 101.7 8.5 1e-06 29.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP87910.1 - 8e-19 67.7 3.5 1.1e-06 28.8 0.1 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP87910.1 - 2.6e-08 34.0 0.0 0.023 14.6 0.0 3.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PRP87910.1 - 1.1e-07 31.2 1.7 0.084 11.8 0.1 4.6 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 PRP87910.1 - 0.017 14.5 0.3 2.1 7.6 0.0 3.1 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 PRP87910.1 - 0.046 13.7 0.0 4.5 7.3 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 PRP87910.1 - 0.069 12.2 0.1 2.3 7.2 0.0 2.1 1 1 1 2 2 2 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 PRP87910.1 - 0.096 11.2 0.1 0.64 8.5 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 PRP87910.1 - 0.83 8.2 10.8 0.036 12.7 0.7 3.3 3 2 1 4 4 4 0 Nucleoporin Nup120/160 His_Phos_1 PF00300.22 PRP87911.1 - 1.2e-25 90.3 0.0 8.2e-18 64.8 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Thioredoxin PF00085.20 PRP87912.1 - 1.1e-62 208.4 0.0 5.3e-30 103.4 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 PRP87912.1 - 5.9e-30 104.5 0.0 1.7e-22 80.3 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 PRP87912.1 - 5.1e-10 39.8 0.1 0.0013 19.1 0.0 3.5 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 PRP87912.1 - 5.9e-09 35.9 0.0 4.7e-05 23.3 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_7 PF13899.6 PRP87912.1 - 4.3e-07 30.0 0.0 0.062 13.5 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 PRP87912.1 - 6.6e-07 29.6 0.0 0.14 12.5 0.0 3.8 2 1 1 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.17 PRP87912.1 - 1.1e-06 28.0 0.1 2.3e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Calsequestrin TraF PF13728.6 PRP87912.1 - 6.3e-06 26.2 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 PRP87912.1 - 8.6e-05 22.3 0.0 0.02 14.6 0.0 2.7 2 0 0 2 2 2 1 Redoxin HyaE PF07449.11 PRP87912.1 - 0.0046 16.9 0.0 0.87 9.6 0.0 3.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE DUF1917 PF08939.10 PRP87912.1 - 0.05 13.5 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) HTH_6 PF01418.17 PRP87912.1 - 0.087 12.8 0.0 12 5.9 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Laminin_G_3 PF13385.6 PRP87913.1 - 2.3e-37 128.5 0.8 2.1e-19 70.2 0.1 2.8 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Steroid_dh PF02544.16 PRP87913.1 - 1e-07 32.1 1.8 2.2e-07 31.0 1.8 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Toxin_R_bind_N PF07953.12 PRP87913.1 - 0.00015 21.5 1.2 0.0074 16.0 0.1 2.8 2 1 0 2 2 2 1 Clostridium neurotoxin, N-terminal receptor binding E1_DerP2_DerF2 PF02221.15 PRP87914.1 - 2.7e-20 73.1 0.3 3.3e-20 72.9 0.3 1.1 1 0 0 1 1 1 1 ML domain DUF4625 PF15418.6 PRP87914.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) F-box-like PF12937.7 PRP87915.1 - 1.1e-05 25.2 1.2 3.2e-05 23.7 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP87915.1 - 0.0033 17.3 0.1 0.0073 16.2 0.1 1.6 1 0 0 1 1 1 1 F-box domain CsbD PF05532.12 PRP87916.1 - 0.0069 16.3 5.9 0.0094 15.8 1.3 2.1 2 0 0 2 2 2 2 CsbD-like Ribosomal_L32p PF01783.23 PRP87917.1 - 7.6e-07 29.3 2.4 1.1e-06 28.7 2.4 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Sec10 PF07393.11 PRP87918.1 - 1.2e-76 258.7 26.0 7.9e-44 150.2 1.5 3.6 3 1 1 4 4 4 3 Exocyst complex component Sec10 T6SS_TssG PF06996.11 PRP87918.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion, TssG DUF2457 PF10446.9 PRP87918.1 - 0.29 10.3 8.5 0.48 9.5 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kelch_3 PF13415.6 PRP87919.1 - 9.1e-30 102.4 10.7 9.4e-05 22.6 0.0 6.9 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 PRP87919.1 - 4.9e-25 86.9 25.1 8.3e-09 34.9 0.6 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 PRP87919.1 - 9e-24 83.0 16.7 0.00011 22.1 0.5 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PRP87919.1 - 1.9e-22 78.3 16.2 5.3e-09 35.7 0.4 5.8 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 PRP87919.1 - 2.1e-21 75.4 17.3 5.6e-06 26.5 0.3 6.6 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PRP87919.1 - 3.2e-20 71.9 11.1 0.00028 20.8 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain BTB PF00651.31 PRP87919.1 - 4.1e-17 62.4 0.7 3.8e-16 59.3 0.1 2.5 1 1 1 2 2 2 1 BTB/POZ domain Adaptin_binding PF10199.9 PRP87920.1 - 0.23 12.1 2.5 0.29 11.8 2.5 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Asn_synthase PF00733.21 PRP87921.1 - 8.1e-66 223.1 0.0 1.2e-65 222.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 PRP87921.1 - 2e-32 111.7 0.0 4e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PRP87921.1 - 9.4e-24 84.1 0.0 1.6e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 PRP87921.1 - 0.00043 19.8 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 PRP87921.1 - 0.039 13.1 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD synthase AAA PF00004.29 PRP87924.1 - 6.3e-83 275.8 0.0 3.4e-43 147.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP87924.1 - 1.1e-21 76.4 6.2 1.5e-12 47.1 1.0 3.4 2 1 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 PRP87924.1 - 1.7e-11 44.8 2.3 0.0012 19.3 0.2 4.5 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 PRP87924.1 - 8e-11 41.9 0.0 0.00018 21.3 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PRP87924.1 - 8.3e-11 42.0 0.0 6.4e-05 23.0 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PRP87924.1 - 3.3e-10 40.3 0.0 8.9e-05 22.8 0.0 2.7 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 PRP87924.1 - 1.2e-09 38.4 0.0 0.0019 18.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 PRP87924.1 - 5.4e-09 36.4 0.9 0.023 14.9 0.0 3.9 3 2 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 PRP87924.1 - 7.2e-09 35.3 0.5 0.00084 18.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 PRP87924.1 - 1.8e-08 34.7 0.0 0.0074 16.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 PRP87924.1 - 2.7e-08 33.6 3.9 0.16 11.6 0.2 4.3 2 2 2 4 4 4 3 AAA domain ABC_tran PF00005.27 PRP87924.1 - 3.4e-08 34.1 0.6 0.0029 18.1 0.0 3.3 3 0 0 3 3 3 2 ABC transporter IstB_IS21 PF01695.17 PRP87924.1 - 3.9e-08 33.2 0.1 0.0035 17.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 PRP87924.1 - 1.1e-07 31.9 0.0 0.00012 22.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 PRP87924.1 - 2.2e-07 30.8 1.0 0.013 15.5 0.1 3.1 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain ATPase_2 PF01637.18 PRP87924.1 - 3e-07 30.6 0.1 0.29 11.0 0.0 4.2 4 2 1 5 5 3 2 ATPase domain predominantly from Archaea TIP49 PF06068.13 PRP87924.1 - 1.6e-06 27.6 0.2 0.041 13.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activat PF00158.26 PRP87924.1 - 3.4e-06 26.9 0.0 0.035 13.8 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_33 PF13671.6 PRP87924.1 - 4.1e-06 27.0 0.0 0.02 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PRP87924.1 - 6.3e-06 26.8 0.2 0.23 12.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain ATPase PF06745.13 PRP87924.1 - 9.1e-06 25.2 1.7 0.32 10.3 0.0 3.7 2 1 1 3 3 3 2 KaiC AAA_7 PF12775.7 PRP87924.1 - 1.7e-05 24.4 0.0 0.08 12.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 PRP87924.1 - 1.8e-05 24.1 0.1 0.073 12.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Bac_DnaA PF00308.18 PRP87924.1 - 2.3e-05 24.4 0.0 0.02 14.8 0.0 2.8 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_28 PF13521.6 PRP87924.1 - 0.00017 21.9 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 PRP87924.1 - 0.0002 21.4 0.0 0.77 9.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 PRP87924.1 - 0.00028 20.1 0.1 0.33 10.0 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Rad17 PF03215.15 PRP87924.1 - 0.0006 19.8 0.2 0.84 9.5 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain DUF2075 PF09848.9 PRP87924.1 - 0.0008 18.8 0.2 0.32 10.2 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 PRP87924.1 - 0.0011 18.8 0.0 0.39 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PRP87924.1 - 0.0012 18.6 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 PRP87924.1 - 0.0015 18.0 0.6 0.65 9.4 0.0 2.8 3 0 0 3 3 2 1 PhoH-like protein PduV-EutP PF10662.9 PRP87924.1 - 0.0027 17.5 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 PRP87924.1 - 0.0061 16.9 1.7 3.7 7.9 0.2 2.8 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 PRP87924.1 - 0.0069 16.5 0.3 5.6 7.1 0.1 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain ATP-synt_ab PF00006.25 PRP87924.1 - 0.0076 15.9 0.2 0.74 9.4 0.0 2.9 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 PRP87924.1 - 0.0078 16.3 0.2 1.7 8.7 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 PRP87924.1 - 0.01 15.6 0.1 4 7.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 PRP87924.1 - 0.014 14.5 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 PRP87924.1 - 0.016 15.1 0.4 10 6.0 0.0 3.1 2 1 1 3 3 3 0 NTPase AAA_3 PF07726.11 PRP87924.1 - 0.016 15.1 0.0 5.8 6.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 PRP87924.1 - 0.019 14.2 0.9 5.6 6.2 0.1 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 PRP87924.1 - 0.019 14.7 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zot PF05707.12 PRP87924.1 - 0.044 13.4 0.0 18 4.9 0.0 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.6 PRP87924.1 - 0.094 13.1 4.0 8.2 6.9 0.1 2.9 3 0 0 3 3 2 0 AAA domain DLIC PF05783.11 PRP87924.1 - 0.15 10.8 0.3 2 7.2 0.0 2.6 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) AAA_23 PF13476.6 PRP87924.1 - 0.17 12.3 2.1 13 6.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain Alpha-amylase PF00128.24 PRP87925.1 - 3.2e-10 40.1 0.0 1.1e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain TMEM234 PF10639.9 PRP87926.1 - 4.9e-36 123.3 3.3 5.7e-36 123.1 3.3 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 PRP87926.1 - 2.6e-07 30.9 7.3 3.2e-05 24.1 7.3 2.1 1 1 0 1 1 1 1 EamA-like transporter family DUF4536 PF15055.6 PRP87926.1 - 0.042 14.1 0.2 0.23 11.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) MFS_1 PF07690.16 PRP87927.1 - 1e-28 100.3 105.2 1.6e-15 56.9 38.2 4.1 2 2 1 4 4 4 3 Major Facilitator Superfamily zf-C2H2 PF00096.26 PRP87927.1 - 1.2e-16 60.1 49.3 5.7e-05 23.4 0.1 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP87927.1 - 1.9e-12 46.9 50.0 0.012 16.4 0.7 7.5 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 PRP87927.1 - 7.4e-10 38.8 41.7 6.2e-05 23.2 0.9 7.2 7 0 0 7 7 7 4 Zinc-finger double domain zf-Di19 PF05605.12 PRP87927.1 - 0.00086 19.5 2.9 0.00086 19.5 2.9 4.1 3 1 0 4 4 3 1 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 PRP87927.1 - 0.0094 15.5 2.3 0.53 9.9 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger Orf78 PF06024.12 PRP87927.1 - 0.016 15.5 3.7 2.1 8.7 0.3 3.5 2 0 0 2 2 2 0 Orf78 (ac78) Merozoite_SPAM PF07133.11 PRP87927.1 - 0.067 13.2 8.3 0.12 12.4 8.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) zf-C2H2_8 PF15909.5 PRP87927.1 - 0.069 13.5 0.2 0.069 13.5 0.2 3.7 2 1 0 3 3 3 0 C2H2-type zinc ribbon zf-DNA_Pol PF08996.10 PRP87927.1 - 0.09 12.5 9.5 2 8.1 3.5 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger zf-BED PF02892.15 PRP87927.1 - 0.093 12.8 14.7 0.87 9.7 1.9 4.0 2 1 1 3 3 3 0 BED zinc finger CDC45 PF02724.14 PRP87927.1 - 1.3 7.2 3.5 1.9 6.7 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Ogr_Delta PF04606.12 PRP87927.1 - 2.4 8.2 10.2 5.7 7.0 1.8 2.9 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger PBP1_TM PF14812.6 PRP87927.1 - 3.1 8.2 6.7 7.7 7.0 6.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn-ribbon_8 PF09723.10 PRP87927.1 - 7.1 6.8 6.4 25 5.1 0.9 2.8 1 1 1 2 2 2 0 Zinc ribbon domain zf-H2C2_5 PF13909.6 PRP87927.1 - 9.4 6.1 39.0 0.053 13.3 2.1 7.2 7 1 0 7 7 7 0 C2H2-type zinc-finger domain E1_DerP2_DerF2 PF02221.15 PRP87928.1 - 3.2e-16 60.0 0.1 6e-16 59.1 0.1 1.5 1 0 0 1 1 1 1 ML domain UPF0020 PF01170.18 PRP87928.1 - 1.7e-08 34.4 0.2 1.9e-07 30.9 0.2 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 PRP87928.1 - 0.0091 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 PRP87928.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase DUF4203 PF13886.6 PRP87929.1 - 0.0058 16.3 0.0 0.0074 16.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Acyl-ACP_TE PF01643.17 PRP87930.1 - 3.1e-12 46.3 3.6 1.3e-08 34.5 2.0 2.9 2 1 0 2 2 2 2 Acyl-ACP thioesterase 4HBT_2 PF13279.6 PRP87930.1 - 3.6e-09 37.2 2.8 0.00011 22.7 0.6 2.2 2 0 0 2 2 2 2 Thioesterase-like superfamily 4HBT PF03061.22 PRP87930.1 - 9.5e-07 29.1 0.2 0.064 13.6 0.0 2.7 2 1 0 2 2 2 2 Thioesterase superfamily PT PF04886.12 PRP87931.1 - 0.074 12.6 144.1 0.089 12.3 17.5 11.7 8 4 0 8 8 8 0 PT repeat Pkinase PF00069.25 PRP87932.1 - 1.7e-62 211.2 0.0 2.9e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP87932.1 - 7.2e-22 77.9 0.0 1.3e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP87932.1 - 0.00015 21.2 0.0 0.00057 19.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Peptidase_C2 PF00648.21 PRP87932.1 - 0.00025 20.2 0.0 0.00054 19.1 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease APH PF01636.23 PRP87932.1 - 0.0047 16.9 0.5 0.12 12.3 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family ABC_membrane_2 PF06472.15 PRP87933.1 - 4.4e-60 203.4 4.9 6.4e-60 202.8 4.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PRP87933.1 - 1.9e-15 57.6 0.0 3.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 PRP87933.1 - 2.9e-05 23.7 0.0 7.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PRP87933.1 - 3e-05 24.0 0.1 9.6e-05 22.3 0.1 1.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PRP87933.1 - 4.1e-05 24.2 0.0 9.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP87933.1 - 0.00033 21.1 0.0 0.00082 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_27 PF13514.6 PRP87933.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PRP87933.1 - 0.033 13.6 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 PRP87933.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 PRP87933.1 - 0.096 10.2 0.2 0.21 9.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) cobW PF02492.19 PRP87933.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 PRP87933.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 PRP87933.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 PRP87933.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP87933.1 - 0.16 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Yip1 PF04893.17 PRP87933.1 - 9.7 5.9 18.2 1.2 8.9 3.5 3.1 3 0 0 3 3 3 0 Yip1 domain Ser_hydrolase PF06821.13 PRP87934.1 - 0.00038 20.3 0.0 0.00055 19.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.16 PRP87934.1 - 0.023 14.5 0.0 0.069 12.9 0.0 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase ARL17 PF15840.5 PRP87934.1 - 0.053 13.9 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 Abhydrolase_6 PF12697.7 PRP87934.1 - 0.081 13.5 0.0 0.11 13.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family ParA PF10609.9 PRP87936.1 - 3.1e-101 338.0 0.0 3.6e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 PRP87936.1 - 2.2e-12 47.1 0.0 3e-10 40.2 0.0 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PRP87936.1 - 1.4e-08 34.9 0.1 1.8e-07 31.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 PRP87936.1 - 7.9e-08 31.8 0.1 2.6e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 PRP87936.1 - 6.4e-05 22.4 0.0 0.00016 21.1 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 PRP87936.1 - 0.00057 19.4 0.1 0.017 14.6 0.0 2.7 2 1 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 PRP87936.1 - 0.0038 16.8 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 PRP87936.1 - 0.0065 16.0 0.0 0.019 14.5 0.0 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 PRP87936.1 - 0.0079 16.1 0.2 0.017 15.0 0.0 1.5 2 0 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 PRP87936.1 - 0.013 14.4 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 PRP87936.1 - 0.016 15.0 0.1 3.7 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PRP87936.1 - 0.023 15.1 0.0 0.047 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 PRP87936.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 PRP87936.1 - 0.066 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 NACHT domain TF_Zn_Ribbon PF08271.12 PRP87936.1 - 0.085 12.4 0.2 0.22 11.1 0.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding SRP54 PF00448.22 PRP87936.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CLP1_P PF16575.5 PRP87936.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Glyco_hydro_18 PF00704.28 PRP87937.1 - 4.3e-18 66.1 0.7 5.8e-18 65.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP87937.1 - 1.6e-06 28.5 9.0 3.2e-06 27.5 9.0 1.4 1 0 0 1 1 1 1 Chitin recognition protein Trypan_PARP PF05887.11 PRP87937.1 - 0.062 13.3 8.1 0.14 12.1 8.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EamA PF00892.20 PRP87938.1 - 0.00046 20.4 17.1 0.00046 20.4 17.1 3.4 2 2 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 PRP87938.1 - 0.0018 17.6 13.7 0.0023 17.2 7.7 2.4 1 1 1 2 2 2 2 Purine nucleobase transmembrane transport DUF202 PF02656.15 PRP87938.1 - 0.095 13.2 16.7 19 5.8 0.8 4.9 3 2 0 3 3 3 0 Domain of unknown function (DUF202) SLC35F PF06027.12 PRP87938.1 - 0.23 11.0 17.8 1.5 8.2 17.4 2.5 1 1 0 1 1 1 0 Solute carrier family 35 TFB6 PF17110.5 PRP87939.1 - 0.37 10.5 3.8 0.4 10.4 3.8 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 PRP87939.1 - 0.58 9.8 4.1 0.59 9.8 4.1 1.2 1 0 0 1 1 1 0 FAM176 family Zip PF02535.22 PRP87939.1 - 1.2 8.3 5.6 1.2 8.2 5.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 PRP87939.1 - 4.4 5.1 5.1 4.2 5.2 5.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 PRP87939.1 - 6 6.6 4.8 6.2 6.5 4.8 1.1 1 0 0 1 1 1 0 Connexin EBV-NA3 PF05009.12 PRP87940.1 - 0.47 9.9 2.3 0.77 9.2 2.3 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CENP-B_dimeris PF09026.10 PRP87940.1 - 4.2 7.8 10.7 53 4.3 11.6 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Esterase_phd PF10503.9 PRP87941.1 - 5.2e-07 29.4 0.0 1.8e-06 27.6 0.0 1.7 1 1 1 2 2 2 1 Esterase PHB depolymerase AXE1 PF05448.12 PRP87941.1 - 0.00084 18.1 0.0 0.051 12.3 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 PRP87941.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PRP87941.1 - 0.0027 17.2 0.1 0.0047 16.4 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AAA_6 PF12774.7 PRP87942.1 - 3.9e-134 446.7 0.0 7.7e-134 445.8 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PRP87942.1 - 1.4e-117 393.2 9.8 1.4e-117 393.2 9.8 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 PRP87942.1 - 2e-79 265.8 0.1 2e-79 265.8 0.1 2.4 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 PRP87942.1 - 5.8e-76 255.3 0.7 1.5e-75 253.9 0.1 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PRP87942.1 - 3.2e-73 246.6 0.4 2.7e-72 243.6 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 PRP87942.1 - 8.7e-54 181.8 0.0 2e-49 167.6 0.0 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 PRP87942.1 - 3e-49 167.9 1.4 3e-49 167.9 1.4 1.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PRP87942.1 - 2.3e-48 164.1 0.0 6.1e-48 162.7 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PRP87942.1 - 5e-41 139.5 0.1 4.1e-37 126.9 0.0 4.6 5 0 0 5 5 4 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PRP87942.1 - 2.4e-21 76.1 0.8 5.1e-20 71.9 0.8 2.8 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PRP87942.1 - 4.7e-19 68.7 0.0 9.4e-05 22.4 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Cadherin_3 PF16184.5 PRP87942.1 - 1.2e-10 41.4 17.1 0.011 15.7 0.0 10.4 11 0 0 11 11 11 2 Cadherin-like AAA_16 PF13191.6 PRP87942.1 - 1.4e-09 38.6 0.1 0.57 10.6 0.0 5.4 4 0 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.6 PRP87942.1 - 2.4e-08 34.3 0.3 0.44 10.8 0.0 5.4 5 0 0 5 5 5 2 AAA domain AAA_lid_1 PF17857.1 PRP87942.1 - 2.8e-08 33.9 0.1 1.1e-07 32.0 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 PRP87942.1 - 1e-06 29.2 0.0 0.84 10.1 0.0 4.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Big_9 PF17963.1 PRP87942.1 - 1.6e-06 28.8 164.4 0.0042 17.8 13.2 18.2 17 2 0 17 17 16 7 Bacterial Ig domain RNA_helicase PF00910.22 PRP87942.1 - 0.019 15.3 0.2 13 6.2 0.0 3.9 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 PRP87942.1 - 0.037 13.8 0.3 1.6 8.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 PRP87942.1 - 0.066 12.6 0.7 11 5.3 0.0 3.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Laminin_II PF06009.12 PRP87942.1 - 1.8 8.6 4.6 11 6.1 0.4 3.7 2 0 0 2 2 2 0 Laminin Domain II Cadherin_5 PF17892.1 PRP87942.1 - 4.3 7.4 38.9 0.017 15.1 0.5 8.6 9 0 0 9 9 8 0 Cadherin-like domain Cyt-b5 PF00173.28 PRP87943.1 - 2e-16 59.9 0.1 3.3e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CDGSH PF09360.10 PRP87943.1 - 1.3e-05 25.3 1.8 1.9e-05 24.8 0.3 2.1 3 0 0 3 3 3 1 Iron-binding zinc finger CDGSH type Methyltransf_28 PF02636.17 PRP87943.1 - 0.073 12.7 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ank_5 PF13857.6 PRP87944.1 - 3e-18 65.6 1.8 3.8e-10 39.8 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP87944.1 - 4.8e-15 55.9 0.1 1.5e-14 54.4 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PRP87944.1 - 5.5e-14 51.9 0.5 3.9e-07 30.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 PRP87944.1 - 3e-13 49.4 13.9 4.2e-13 48.9 13.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 PRP87944.1 - 3.7e-13 49.7 0.2 1.9e-12 47.4 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP87944.1 - 5.4e-12 44.8 0.4 6.9e-05 23.0 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Prok-RING_4 PF14447.6 PRP87944.1 - 1.7e-06 27.8 14.2 2.9e-06 27.0 14.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP87944.1 - 0.0034 17.3 13.6 0.0052 16.7 13.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain AF0941-like PF14591.6 PRP87944.1 - 0.78 10.3 3.5 5.3 7.7 0.1 2.4 1 1 1 2 2 2 0 AF0941-like Aminotran_1_2 PF00155.21 PRP87945.1 - 6.5e-40 137.4 0.0 8e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PRP87945.1 - 0.00046 19.6 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SpoVAE PF14097.6 PRP87945.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AE1 FMN_dh PF01070.18 PRP87946.1 - 3.6e-127 424.2 0.0 4.1e-127 424.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 PRP87946.1 - 2.6e-05 23.4 0.3 0.00015 20.9 0.0 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 PRP87946.1 - 0.0001 21.8 0.2 0.0002 20.8 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 PRP87946.1 - 0.00016 20.9 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 PRP87946.1 - 0.0017 17.8 0.0 0.09 12.2 0.0 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 PRP87946.1 - 0.008 15.5 0.1 0.29 10.4 0.0 2.7 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 PRP87946.1 - 0.058 12.6 0.0 0.14 11.3 0.0 1.6 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase GAS2 PF02187.17 PRP87947.1 - 1.6e-05 24.9 0.1 4.8e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Musclin PF11037.8 PRP87947.1 - 0.041 13.8 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle DUF2387 PF09526.10 PRP87947.1 - 3.8 7.7 6.6 21 5.4 3.0 3.1 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) SpoIISA_toxin PF14171.6 PRP87947.1 - 4.3 7.0 4.7 13 5.4 4.7 1.8 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF4709 PF15821.5 PRP87947.1 - 8.7 6.7 15.7 0.48 10.7 6.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4709) 2OG-FeII_Oxy_3 PF13640.6 PRP87951.1 - 1e-12 48.8 0.0 1.8e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Paramyxo_PNT PF14320.6 PRP87951.1 - 0.0053 16.0 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 2 Phosphoprotein P region PNT disordered Pro-kuma_activ PF09286.11 PRP87952.1 - 8.3e-15 55.3 0.2 1.3e-14 54.7 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP87952.1 - 2.1e-09 37.1 0.2 2.8e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 Subtilase family Tombus_P19 PF03220.13 PRP87952.1 - 0.048 13.4 0.0 3.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Tombusvirus P19 core protein SARS_3b PF12383.8 PRP87952.1 - 0.049 13.7 0.3 0.049 13.7 0.3 1.6 2 0 0 2 2 2 0 Severe acute respiratory syndrome coronavirus 3b protein Homeodomain PF00046.29 PRP87953.1 - 2.7e-09 36.7 0.3 1.7e-05 24.5 0.1 2.2 2 0 0 2 2 2 2 Homeodomain YdaS_antitoxin PF15943.5 PRP87953.1 - 0.00013 21.7 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HTH_10 PF04967.12 PRP87953.1 - 0.0019 18.0 0.0 0.0093 15.7 0.0 2.1 3 0 0 3 3 3 1 HTH DNA binding domain HTH_28 PF13518.6 PRP87953.1 - 0.003 17.7 0.2 0.01 16.0 0.1 1.9 1 1 1 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 PRP87953.1 - 0.0091 15.8 0.1 0.03 14.1 0.1 1.9 1 1 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 PRP87953.1 - 0.017 15.0 0.0 0.056 13.4 0.0 1.8 2 0 0 2 2 2 0 Homeobox KN domain Homez PF11569.8 PRP87953.1 - 0.026 14.0 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_36 PF13730.6 PRP87953.1 - 0.088 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain BrkDBD PF09607.10 PRP87953.1 - 0.94 9.3 3.7 0.47 10.3 0.5 2.0 2 1 0 2 2 2 0 Brinker DNA-binding domain Homeodomain PF00046.29 PRP87954.1 - 0.028 14.3 3.0 0.083 12.7 3.0 1.8 1 0 0 1 1 1 0 Homeodomain Neur_chan_memb PF02932.16 PRP87954.1 - 0.58 10.2 4.5 0.97 9.4 4.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.11 PRP87954.1 - 0.71 9.9 13.0 1.1 9.3 13.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LMBR1 PF04791.16 PRP87954.1 - 4.8 6.0 6.2 6.6 5.5 6.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2852 PF11014.8 PRP87954.1 - 5.3 7.2 10.8 15 5.8 10.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) Glyco_hydro_cc PF11790.8 PRP87955.1 - 3.2e-46 157.8 1.6 4.4e-46 157.4 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PAN_4 PF14295.6 PRP87955.1 - 1.2e-11 44.3 5.5 1.2e-11 44.3 5.5 3.0 3 1 0 3 3 3 1 PAN domain Chitin_bind_1 PF00187.19 PRP87955.1 - 1.6e-06 28.5 23.1 1.6e-06 28.5 23.1 2.7 2 1 0 2 2 2 1 Chitin recognition protein PAXIP1_C PF15364.6 PRP87956.1 - 0.018 15.3 0.3 0.019 15.2 0.3 1.0 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein TERF2_RBM PF16772.5 PRP87956.1 - 0.48 9.9 2.2 1.8 8.1 2.2 1.8 1 1 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif Sel1 PF08238.12 PRP87958.1 - 2.5e-59 196.4 39.1 3.5e-08 33.8 0.1 12.5 13 0 0 13 13 13 9 Sel1 repeat TPR_6 PF13174.6 PRP87958.1 - 0.14 12.8 19.6 42 5.1 0.0 8.2 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP87958.1 - 0.26 12.2 17.9 19 6.4 0.5 7.9 7 2 2 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP87958.1 - 2.8 8.3 38.6 1.4 9.2 0.4 9.3 9 1 1 10 10 10 0 Tetratricopeptide repeat RGS PF00615.19 PRP87959.1 - 1.6e-29 102.5 0.2 2.4e-29 102.0 0.2 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain GRAM PF02893.20 PRP87960.1 - 9.6e-06 25.5 0.0 4.3e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 GRAM domain Utp11 PF03998.13 PRP87962.1 - 3.1e-34 119.0 33.7 3.6e-34 118.8 33.7 1.0 1 0 0 1 1 1 1 Utp11 protein RNase_HII PF01351.18 PRP87962.1 - 0.036 13.9 0.8 0.036 13.9 0.8 2.2 2 1 0 2 2 2 0 Ribonuclease HII THF_DHG_CYH PF00763.23 PRP87962.1 - 0.41 10.9 6.2 0.11 12.8 2.2 2.0 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Asp-B-Hydro_N PF05279.11 PRP87962.1 - 4.5 7.3 18.1 7.5 6.5 18.1 1.4 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RhoGAP PF00620.27 PRP87963.1 - 1.7e-43 148.1 0.6 4.2e-43 146.8 0.6 1.7 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 PRP87963.1 - 8.8e-06 26.2 0.2 4.2e-05 24.0 0.2 2.2 1 1 0 1 1 1 1 PH domain PH_13 PF16652.5 PRP87963.1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1708 PF08101.11 PRP87963.1 - 0.00066 19.0 0.0 0.0014 17.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) PH_9 PF15410.6 PRP87963.1 - 0.0047 17.3 0.5 0.18 12.2 0.0 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 PRP87963.1 - 0.087 13.1 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain adh_short PF00106.25 PRP87964.1 - 2.5e-19 69.5 0.0 1.3e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP87964.1 - 9e-13 48.3 0.0 5.3e-08 32.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PRP87964.1 - 0.0035 16.8 0.1 0.38 10.2 0.0 2.1 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 PRP87964.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 PRP87964.1 - 0.044 12.9 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 PRP87964.1 - 0.057 13.3 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding NAD_binding_4 PF07993.12 PRP87964.1 - 0.061 12.5 0.0 1.1 8.3 0.0 2.0 1 1 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 PRP87964.1 - 0.067 12.6 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Mur_ligase PF01225.25 PRP87964.1 - 0.18 12.2 0.0 0.4 11.0 0.0 1.6 2 0 0 2 2 2 0 Mur ligase family, catalytic domain LRR_8 PF13855.6 PRP87965.1 - 3.4e-11 42.7 10.1 2.5e-08 33.5 3.2 2.5 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 PRP87965.1 - 5.2e-09 35.4 11.7 0.0016 18.7 0.4 4.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_4 PF12799.7 PRP87965.1 - 4.3e-08 33.3 29.5 0.00032 21.0 1.6 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP87965.1 - 0.3 11.2 0.4 0.3 11.2 0.4 4.2 4 0 0 4 4 4 0 Leucine Rich repeat FNIP PF05725.12 PRP87965.1 - 0.52 10.5 10.5 11 6.3 1.8 3.8 1 1 2 3 3 3 0 FNIP Repeat Rap_GAP PF02145.15 PRP87966.1 - 2.8e-11 43.3 0.0 1.8e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 Rap/ran-GAP AhpC-TSA_2 PF13911.6 PRP87966.1 - 2.4e-05 24.4 0.0 6.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AMPK1_CBM PF16561.5 PRP87967.1 - 0.07 13.4 0.1 0.11 12.7 0.1 1.4 1 1 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase dCMP_cyt_deam_1 PF00383.23 PRP87967.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region NDK PF00334.19 PRP87968.1 - 1.1e-36 125.9 0.0 1.3e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase GT87 PF09594.10 PRP87970.1 - 0.36 10.5 7.4 0.49 10.1 7.4 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 MotA_ExbB PF01618.16 PRP87970.1 - 2.1 8.1 4.7 15 5.4 1.0 2.2 1 1 1 2 2 2 0 MotA/TolQ/ExbB proton channel family UCR_Fe-S_N PF10399.9 PRP87970.1 - 3.4 7.1 9.2 6.6 6.2 1.8 2.5 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MJ1316 PF04457.12 PRP87971.1 - 2.7e-08 34.4 0.3 6.9e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain PrmA PF06325.13 PRP87972.1 - 3.3e-10 39.8 0.0 4.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PRP87972.1 - 3.3e-08 33.5 0.0 4.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP87972.1 - 1.3e-06 28.0 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PRP87972.1 - 1e-05 26.2 0.0 2.8e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PRMT5_C PF17286.2 PRP87972.1 - 3.3e-05 23.8 0.0 5.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Cons_hypoth95 PF03602.15 PRP87972.1 - 0.00038 20.1 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 PRP87972.1 - 0.00042 20.1 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.16 PRP87972.1 - 0.00072 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 PRP87972.1 - 0.001 19.8 0.0 0.0017 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PRP87972.1 - 0.0028 17.7 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 PRP87972.1 - 0.0089 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase JTB PF05439.12 PRP87973.1 - 0.01 15.9 9.1 0.1 12.6 1.1 2.3 1 1 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) COX17 PF05051.13 PRP87973.1 - 0.046 14.1 0.3 0.046 14.1 0.3 1.6 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) zf-SNAP50_C PF12251.8 PRP87976.1 - 7.9e-63 211.7 7.4 7.9e-63 211.7 7.4 1.9 3 0 0 3 3 3 1 snRNA-activating protein of 50kDa MW C terminal TPR_2 PF07719.17 PRP87976.1 - 3.3e-11 42.4 6.0 0.0018 18.2 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP87976.1 - 1.3e-08 34.9 9.4 0.29 11.5 0.1 6.5 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 PRP87976.1 - 7.2e-07 28.9 1.2 0.014 15.5 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP87976.1 - 8.6e-07 28.5 1.9 0.1 12.4 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP87976.1 - 5.3e-05 23.7 0.4 0.21 12.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP87976.1 - 0.00052 19.6 1.0 2.2 8.1 0.1 4.2 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 PRP87976.1 - 0.0015 19.2 11.3 0.87 10.6 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP87976.1 - 0.003 18.2 0.2 1.5 9.5 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PRP87976.1 - 0.066 13.3 11.0 0.1 12.6 0.1 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PRP87976.1 - 0.35 11.6 7.0 34 5.4 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP87976.1 - 1.1 9.2 3.4 2.9 7.9 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Thiolase_N PF00108.23 PRP87977.1 - 1.2e-15 57.6 0.2 1.2e-12 47.7 0.1 2.7 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PRP87977.1 - 1.7e-10 40.6 0.2 3.7e-10 39.5 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 PRP87977.1 - 0.00012 21.9 0.3 0.038 13.8 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 PRP87977.1 - 0.0022 18.0 0.0 0.22 11.5 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 PRP87977.1 - 0.014 14.2 0.0 0.036 12.8 0.0 1.8 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 PRP87977.1 - 0.043 13.4 0.1 0.11 12.1 0.1 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Proteasome PF00227.26 PRP87978.1 - 1.1e-37 129.3 0.0 1.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Iwr1 PF08574.10 PRP87979.1 - 1.8e-07 32.1 18.5 1.8e-07 32.1 18.5 4.0 3 1 0 3 3 3 1 Transcription factor Iwr1 Costars PF14705.6 PRP87980.1 - 3.5e-22 78.4 0.1 4.2e-22 78.1 0.1 1.0 1 0 0 1 1 1 1 Costars Hist_deacetyl PF00850.19 PRP87981.1 - 6.2e-82 275.5 0.0 8.1e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain LRR_8 PF13855.6 PRP87982.1 - 1.3e-57 191.4 79.3 1.1e-09 37.9 8.1 10.7 6 3 7 13 13 12 11 Leucine rich repeat LRR_4 PF12799.7 PRP87982.1 - 1.5e-37 126.9 83.4 1.2e-05 25.6 5.1 14.2 6 2 6 15 15 15 12 Leucine Rich repeats (2 copies) WD40 PF00400.32 PRP87982.1 - 1.2e-34 117.7 35.2 1.3e-06 29.0 0.8 8.2 7 0 0 7 7 7 6 WD domain, G-beta repeat LRR_1 PF00560.33 PRP87982.1 - 1.3e-19 67.7 75.4 0.027 15.0 0.4 21.4 18 4 2 20 20 20 6 Leucine Rich Repeat GPS PF01825.21 PRP87982.1 - 8.6e-09 35.8 1.7 2.4e-08 34.4 1.7 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Nup160 PF11715.8 PRP87982.1 - 0.00016 20.5 4.9 0.081 11.6 0.1 4.7 2 2 1 4 4 4 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 PRP87982.1 - 0.00073 19.5 0.1 2 8.5 0.0 3.1 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region TNFR_16_TM PF18422.1 PRP87982.1 - 0.00076 19.4 0.6 0.0015 18.4 0.6 1.5 1 0 0 1 1 1 1 Tumor necrosis factor receptor member 16 trans-membrane domain TMEM154 PF15102.6 PRP87982.1 - 0.001 19.0 0.0 0.001 19.0 0.0 2.5 3 0 0 3 3 2 1 TMEM154 protein family Syndecan PF01034.20 PRP87982.1 - 0.0011 18.8 0.5 0.0022 17.9 0.5 1.4 1 0 0 1 1 1 1 Syndecan domain MitoNEET_N PF10660.9 PRP87982.1 - 0.0035 17.3 5.0 1e+02 3.0 0.0 7.8 9 0 0 9 9 9 0 Iron-containing outer mitochondrial membrane protein N-terminus WD40_like PF17005.5 PRP87982.1 - 0.0053 16.1 0.4 0.44 9.8 0.2 2.2 1 1 1 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 PRP87982.1 - 0.0054 17.0 0.6 2.7 8.4 0.0 4.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP87982.1 - 0.013 14.4 0.2 18 4.2 0.0 3.7 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5408 PF17402.2 PRP87982.1 - 0.24 11.3 0.5 0.54 10.2 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5408) Orf78 PF06024.12 PRP87982.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) LRR_6 PF13516.6 PRP87982.1 - 0.81 9.9 87.5 0.78 9.9 0.8 17.7 18 0 0 18 18 18 0 Leucine Rich repeat Gti1_Pac2 PF09729.9 PRP87982.1 - 1.7 8.7 6.7 4.7 7.3 6.7 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family EphA2_TM PF14575.6 PRP87982.1 - 2.7 8.9 4.0 0.69 10.8 0.1 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain CDC45 PF02724.14 PRP87982.1 - 3.6 5.8 21.5 5.2 5.2 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Fascin PF06268.13 PRP87984.1 - 4.4e-06 26.9 0.2 0.083 13.1 0.0 2.7 2 1 1 3 3 3 2 Fascin domain FRG1 PF06229.12 PRP87984.1 - 0.18 11.5 0.0 7.8 6.2 0.0 2.5 1 1 1 2 2 2 0 FRG1-like domain DUF3432 PF11914.8 PRP87984.1 - 8.4 6.7 17.5 17 5.7 17.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) ArfGap PF01412.18 PRP87985.1 - 7e-25 87.4 0.0 7e-25 87.4 0.0 2.8 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf SH2 PF00017.24 PRP87985.1 - 2.5e-10 40.3 0.1 5.5e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 SH2 domain UBZ_FAAP20 PF15750.5 PRP87985.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger CBM_19 PF03427.13 PRP87985.1 - 0.27 11.2 0.9 0.68 10.0 0.9 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) TFIIA PF03153.13 PRP87985.1 - 0.3 11.1 88.3 0.39 10.7 45.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit START PF01852.19 PRP87986.1 - 9.6e-31 106.8 0.0 1.2e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.8 PRP87986.1 - 7.2e-05 22.9 0.1 0.00015 21.8 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) eIF_4EBP PF05456.11 PRP87987.1 - 8.3e-27 93.4 1.2 1e-26 93.1 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) ubiquitin PF00240.23 PRP87988.1 - 7.9e-16 57.6 0.3 3.1e-14 52.5 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PRP87988.1 - 2.9e-09 36.6 0.1 5.1e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like GRDP-like PF07173.12 PRP87988.1 - 0.0061 17.2 0.2 0.72 10.5 0.1 2.2 1 1 1 2 2 2 2 Glycine-rich domain-containing protein-like DUF4394 PF14339.6 PRP87990.1 - 5e-23 81.7 0.7 5e-23 81.7 0.7 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4394) COesterase PF00135.28 PRP87991.1 - 1.5e-84 284.7 0.0 2.1e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 PRP87991.1 - 9.5e-05 22.2 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 PRP87991.1 - 0.0002 20.9 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 PRP87991.1 - 0.02 14.8 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chromo PF00385.24 PRP87993.1 - 6.6e-11 42.0 0.9 9.6e-11 41.4 0.9 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain VirC1 PF07015.11 PRP87993.1 - 0.11 11.7 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 VirC1 protein Pkinase_Tyr PF07714.17 PRP87994.1 - 2.8e-65 220.2 0.0 4.4e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP87994.1 - 6.3e-45 153.6 0.0 1.1e-44 152.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Beta_helix PF13229.6 PRP87994.1 - 2e-13 50.5 107.8 4.9e-06 26.5 19.2 7.3 2 2 5 7 7 7 6 Right handed beta helix region Chlam_PMP PF02415.17 PRP87994.1 - 0.0051 17.2 1.4 0.0051 17.2 1.4 14.1 16 0 0 16 16 16 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kdo PF06293.14 PRP87994.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP87994.1 - 0.063 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pectate_lyase_3 PF12708.7 PRP87995.1 - 7.1e-15 55.4 8.5 7.1e-15 55.4 8.5 2.6 2 1 1 3 3 3 1 Pectate lyase superfamily protein Beta_helix PF13229.6 PRP87995.1 - 3.4e-05 23.8 30.7 0.00054 19.8 6.1 2.6 1 1 3 4 4 4 3 Right handed beta helix region CBM_35 PF16990.5 PRP87995.1 - 0.0051 17.0 0.0 0.017 15.3 0.0 2.0 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) SlpA PF03217.14 PRP87995.1 - 0.14 12.7 0.0 0.72 10.5 0.0 2.1 2 0 0 2 2 2 0 Surface later protein A domain DUF2617 PF10936.8 PRP87996.1 - 0.14 12.3 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2617 ATP-synt_D PF01813.17 PRP87998.1 - 1.2e-68 230.8 1.7 1.5e-68 230.5 1.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D HATPase_c PF02518.26 PRP87999.1 - 1.5e-25 89.9 0.5 3.1e-25 88.9 0.5 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP87999.1 - 3.1e-22 78.9 1.5 3e-21 75.7 0.5 2.8 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 PRP87999.1 - 8.3e-17 61.0 0.0 2.8e-16 59.3 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP87999.1 - 0.00042 20.1 0.1 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3870 PF12986.7 PRP87999.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) AvrE_T3Es PF11725.8 PRP87999.1 - 0.12 9.6 0.0 0.19 8.9 0.0 1.2 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) PAS_3 PF08447.12 PRP87999.1 - 0.13 12.5 0.0 3.8 7.9 0.0 2.8 2 0 0 2 2 2 0 PAS fold Halogen_Hydrol PF10112.9 PRP88000.1 - 0.0099 15.9 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein BRE1 PF08647.11 PRP88000.1 - 0.035 14.2 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase RPN7 PF10602.9 PRP88001.1 - 6.2e-49 166.0 1.0 1.9e-48 164.5 1.0 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN7 SPRY PF00622.28 PRP88001.1 - 8.9e-22 77.4 0.1 1.9e-21 76.4 0.1 1.6 1 0 0 1 1 1 1 SPRY domain PCI PF01399.27 PRP88001.1 - 3.6e-16 59.6 3.9 5.2e-16 59.1 0.0 3.4 5 0 0 5 5 5 1 PCI domain Ufd2P_core PF10408.9 PRP88001.1 - 4.6e-11 42.1 8.0 2.6e-09 36.3 0.4 2.5 2 1 0 2 2 2 2 Ubiquitin elongating factor core zf-C3HC4_3 PF13920.6 PRP88001.1 - 1.3e-08 34.5 11.7 2.9e-08 33.4 11.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP88001.1 - 0.0011 18.7 14.5 0.0011 18.7 14.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP88001.1 - 0.0085 16.4 13.6 0.026 14.8 13.6 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 PRP88001.1 - 0.05 13.5 12.9 0.11 12.4 12.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PRP88001.1 - 0.1 12.5 13.4 0.25 11.2 13.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP88001.1 - 0.66 10.0 12.9 1.6 8.8 12.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_10 PF16685.5 PRP88001.1 - 3.9 7.7 13.0 1.2 9.3 8.5 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Pkinase_Tyr PF07714.17 PRP88002.1 - 5.8e-63 212.6 0.0 4.6e-62 209.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88002.1 - 2.5e-47 161.5 0.0 2.7e-46 158.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP88002.1 - 5.7e-41 137.8 127.7 1.4e-05 25.3 1.2 20.3 14 6 6 22 22 22 19 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP88002.1 - 7.9e-35 118.4 138.4 3.4e-10 39.5 8.7 16.5 9 4 6 16 16 16 14 Leucine rich repeat LRR_6 PF13516.6 PRP88002.1 - 2.1e-06 27.3 97.3 0.23 11.6 0.1 22.9 26 0 0 26 26 25 6 Leucine Rich repeat Kdo PF06293.14 PRP88002.1 - 0.0026 17.2 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_5 PF13306.6 PRP88002.1 - 0.021 14.8 0.8 0.021 14.8 0.8 4.8 5 0 0 5 5 5 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 PRP88002.1 - 0.026 15.0 106.9 5.5 7.9 0.2 24.6 25 6 0 25 25 24 0 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP88002.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 PRP88002.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family LRRNT_2 PF08263.12 PRP88002.1 - 0.1 12.9 2.8 0.21 11.9 2.1 2.0 2 0 0 2 2 1 0 Leucine rich repeat N-terminal domain DUF4690 PF15756.5 PRP88002.1 - 0.15 12.6 0.2 0.37 11.4 0.2 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DSPc PF00782.20 PRP88003.1 - 1.4e-09 37.9 0.0 2.7e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP88003.1 - 2e-08 34.1 0.0 4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 PRP88003.1 - 1.2e-05 25.1 0.0 2.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 PRP88003.1 - 0.0066 16.4 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 PRP88003.1 - 0.033 13.8 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family RII_binding_1 PF10522.9 PRP88003.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 RII binding domain PTPlike_phytase PF14566.6 PRP88003.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Arm PF00514.23 PRP88004.1 - 0.00019 21.3 10.5 2.1 8.5 0.1 6.5 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat Symplekin_C PF12295.8 PRP88004.1 - 0.0014 18.7 0.4 0.0049 17.0 0.4 1.9 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal Peptidase_M50 PF02163.22 PRP88005.1 - 1.3e-21 77.1 0.0 1.3e-20 73.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M50 GCP_C_terminal PF04130.13 PRP88006.1 - 2.3e-45 155.4 3.2 4.3e-45 154.5 3.2 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PRP88006.1 - 3.6e-38 131.9 0.6 1.2e-37 130.2 0.5 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Ank_2 PF12796.7 PRP88006.1 - 4.3e-21 75.3 0.0 1.7e-06 28.5 0.0 4.9 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP88006.1 - 1.4e-14 54.2 7.4 2e-05 25.1 0.1 6.5 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP88006.1 - 4.4e-10 39.6 0.7 0.29 11.5 0.0 6.6 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP88006.1 - 1.9e-07 31.2 11.8 0.9 10.1 0.1 7.9 8 1 1 9 9 9 3 Ankyrin repeat Ank_3 PF13606.6 PRP88006.1 - 2e-07 30.7 2.1 0.94 10.3 0.0 7.1 7 0 0 7 7 7 2 Ankyrin repeat Myticin-prepro PF10690.9 PRP88006.1 - 0.16 12.2 0.4 0.39 11.0 0.4 1.7 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel zf-MYND PF01753.18 PRP88007.1 - 1.1e-05 25.4 8.3 1.1e-05 25.4 8.3 1.9 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 PRP88007.1 - 0.026 14.8 5.1 0.065 13.5 5.1 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding SASA PF03629.18 PRP88008.1 - 2.7e-18 66.4 0.0 7e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase MGC-24 PF05283.11 PRP88008.1 - 0.018 15.5 9.4 0.018 15.5 9.4 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 PRP88008.1 - 0.056 13.4 16.0 0.15 12.0 16.0 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein F-box-like PF12937.7 PRP88009.1 - 2.9e-06 27.1 0.4 5.8e-06 26.1 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP88009.1 - 3.9e-05 23.4 1.2 4.5e-05 23.2 0.2 1.7 2 0 0 2 2 2 1 F-box domain DPBB_1 PF03330.18 PRP88010.1 - 0.042 14.1 0.2 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Lytic transglycolase Reovirus_M2 PF05993.12 PRP88010.1 - 0.12 10.5 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Arf PF00025.21 PRP88011.1 - 4.9e-61 205.2 0.0 7.1e-61 204.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PRP88011.1 - 1.5e-13 50.7 0.0 2.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88011.1 - 2.9e-13 50.1 0.0 4.9e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PRP88011.1 - 2.5e-12 46.6 0.0 8.7e-10 38.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 PRP88011.1 - 5e-11 42.4 0.0 7.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PRP88011.1 - 2e-08 33.9 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP88011.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP88011.1 - 0.0065 16.0 0.1 0.016 14.8 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.19 PRP88011.1 - 0.032 13.8 0.2 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain VWA_2 PF13519.6 PRP88013.1 - 1.3e-05 25.8 0.8 0.00021 21.9 0.4 3.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PRP88013.1 - 3.8e-05 23.2 0.3 7.4e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.28 PRP88013.1 - 0.0018 18.5 1.7 0.0078 16.5 0.1 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain FadR_C PF07840.12 PRP88014.1 - 0.11 12.4 0.4 0.53 10.2 0.0 2.3 3 0 0 3 3 3 0 FadR C-terminal domain PK PF00224.21 PRP88016.1 - 1.4e-150 501.0 7.2 2.3e-150 500.3 7.2 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PRP88016.1 - 3.8e-29 101.3 0.1 2.3e-28 98.8 0.1 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PRP88016.1 - 7.9e-05 21.9 0.4 0.00013 21.2 0.4 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family F-box PF00646.33 PRP88017.1 - 0.0093 15.8 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF3552 PF12072.8 PRP88017.1 - 0.048 13.1 4.4 0.12 11.7 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) KASH_CCD PF14662.6 PRP88017.1 - 1.5 8.6 6.3 0.3 10.9 1.5 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH SASA PF03629.18 PRP88018.1 - 5e-19 68.8 0.0 1.3e-18 67.5 0.0 1.6 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Trp_halogenase PF04820.14 PRP88018.1 - 0.057 12.3 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase SASA PF03629.18 PRP88019.1 - 2.1e-18 66.8 0.0 3.5e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase RicinB_lectin_2 PF14200.6 PRP88019.1 - 0.0034 18.1 0.4 0.0034 18.1 0.4 2.7 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like CarboxypepD_reg PF13620.6 PRP88019.1 - 0.048 13.9 0.3 0.17 12.1 0.3 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Pkinase_Tyr PF07714.17 PRP88020.1 - 4.6e-69 232.6 0.0 8.3e-69 231.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88020.1 - 1.4e-48 165.6 0.0 2.3e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP88020.1 - 2.7e-43 145.6 130.1 2.9e-05 23.7 4.6 17.9 13 5 3 19 19 19 15 Leucine rich repeat LRR_4 PF12799.7 PRP88020.1 - 1.2e-35 120.9 136.2 0.00038 20.8 3.1 20.9 14 5 7 23 23 23 17 Leucine Rich repeats (2 copies) FtsX PF02687.21 PRP88020.1 - 8.5e-15 55.0 21.0 3.6e-09 37.0 6.7 6.3 6 1 0 6 6 6 2 FtsX-like permease family Kdo PF06293.14 PRP88020.1 - 0.00094 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRRNT_2 PF08263.12 PRP88020.1 - 0.014 15.7 1.0 0.038 14.3 1.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Haspin_kinase PF12330.8 PRP88020.1 - 0.024 13.6 0.6 0.21 10.5 0.6 2.2 1 1 0 1 1 1 0 Haspin like kinase domain LRR_9 PF14580.6 PRP88020.1 - 0.11 12.0 16.0 4.5 6.7 0.3 5.5 4 1 1 5 5 5 0 Leucine-rich repeat RCC1 PF00415.18 PRP88021.1 - 3.5e-75 248.4 11.7 2.1e-16 60.3 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP88021.1 - 2e-41 139.0 26.6 4.6e-09 35.8 1.6 8.1 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.23 PRP88021.1 - 3.3e-11 43.2 0.0 5.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PH PF00169.29 PRP88021.1 - 1.4e-08 35.2 0.0 3.9e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.17 PRP88021.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SASA PF03629.18 PRP88023.1 - 3.3e-19 69.4 0.0 7.3e-19 68.3 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase CarboxypepD_reg PF13620.6 PRP88023.1 - 0.0015 18.7 1.8 0.0087 16.3 0.2 2.6 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain RicinB_lectin_2 PF14200.6 PRP88023.1 - 0.012 16.3 0.3 0.012 16.3 0.3 2.5 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like ABC2_membrane_3 PF12698.7 PRP88024.1 - 9.3e-34 117.1 13.2 1.3e-33 116.6 13.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 PRP88024.1 - 5.8e-31 107.6 22.0 2.4e-29 102.3 11.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 PRP88024.1 - 3.6e-28 98.8 0.0 6.5e-24 85.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PRP88024.1 - 5.1e-11 42.9 0.4 2.6e-06 27.5 0.3 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 PRP88024.1 - 2.8e-08 33.4 6.2 3.9e-08 32.9 6.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 PRP88024.1 - 0.039 14.3 0.0 0.084 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 PRP88024.1 - 0.048 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 PRP88024.1 - 0.061 13.8 0.3 0.18 12.2 0.3 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 PRP88024.1 - 0.075 12.9 0.2 0.21 11.4 0.2 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 PRP88024.1 - 0.11 12.8 0.7 0.77 10.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PRP88024.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Pkinase_Tyr PF07714.17 PRP88025.1 - 9.8e-81 270.8 0.0 1.5e-80 270.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88025.1 - 3e-49 167.7 0.0 5.1e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP88025.1 - 2.1e-34 117.1 118.3 3.8e-06 26.6 4.0 14.1 8 4 6 15 15 15 13 Leucine rich repeat LRR_4 PF12799.7 PRP88025.1 - 1.7e-26 91.8 114.1 0.00029 21.1 6.0 15.4 11 3 7 18 18 18 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP88025.1 - 5.7e-11 41.4 81.4 1.1 10.1 0.4 21.4 17 4 1 18 18 18 5 Leucine Rich Repeat Kinase-like PF14531.6 PRP88025.1 - 5.6e-07 29.2 0.0 1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like LRRNT_2 PF08263.12 PRP88025.1 - 0.0012 19.1 0.3 0.004 17.4 0.3 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Pkinase_fungal PF17667.1 PRP88025.1 - 0.015 14.1 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 PRP88025.1 - 0.12 12.5 74.9 1.2 9.3 0.3 16.9 19 0 0 19 19 18 0 Leucine Rich repeat Syndecan PF01034.20 PRP88025.1 - 0.23 11.4 1.2 0.62 10.0 1.2 1.7 1 0 0 1 1 1 0 Syndecan domain DUF347 PF03988.12 PRP88025.1 - 3.5 7.9 6.6 0.38 11.0 1.2 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Adipogenin PF15202.6 PRP88027.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Adipogenin DUF723 PF05265.13 PRP88028.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF723) Peptidase_M50 PF02163.22 PRP88028.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M50 DUF3844 PF12955.7 PRP88028.1 - 2.4 8.3 7.6 0.96 9.6 3.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3844) EGF_2 PF07974.13 PRP88028.1 - 5.1 7.6 7.2 13 6.3 7.2 1.7 1 0 0 1 1 1 0 EGF-like domain IP_trans PF02121.18 PRP88029.1 - 5.2e-69 232.5 2.2 1e-68 231.6 2.2 1.4 1 1 0 1 1 1 1 Phosphatidylinositol transfer protein DUF4483 PF14825.6 PRP88030.1 - 1.9e-06 27.7 2.0 0.024 14.4 0.1 3.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4483) E1-E2_ATPase PF00122.20 PRP88031.1 - 2.7e-50 170.4 1.0 6.4e-50 169.2 1.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 PRP88031.1 - 3.6e-49 167.9 0.6 5.6e-49 167.3 0.6 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 PRP88031.1 - 7.1e-23 80.8 9.9 1e-12 48.3 0.1 3.6 4 0 0 4 4 4 2 Heavy-metal-associated domain SASA PF03629.18 PRP88031.1 - 8.1e-17 61.6 0.0 2.2e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase HAD PF12710.7 PRP88031.1 - 0.00093 19.6 0.0 0.0025 18.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RicinB_lectin_2 PF14200.6 PRP88031.1 - 0.037 14.7 0.6 0.16 12.7 0.6 2.1 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Hydrolase_3 PF08282.12 PRP88031.1 - 0.1 12.3 2.7 0.28 10.9 1.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3429 PF11911.8 PRP88031.1 - 0.23 11.8 4.4 0.12 12.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) SASA PF03629.18 PRP88033.1 - 1.6e-15 57.4 0.0 4.7e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Mlo PF03094.15 PRP88035.1 - 5.7e-13 48.1 31.7 1.4e-06 27.0 4.2 4.0 2 1 2 4 4 4 3 Mlo family Saf_2TM PF18303.1 PRP88035.1 - 2.2 7.8 15.6 0.1 12.2 2.7 2.7 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain HSP20 PF00011.21 PRP88036.1 - 2.4e-17 62.9 0.0 3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PRP88036.1 - 4.2e-08 32.6 0.0 6.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 PRP88036.1 - 0.0016 19.4 0.2 0.0036 18.3 0.0 1.7 2 1 0 2 2 2 1 CS domain GvpH PF05455.11 PRP88036.1 - 0.02 15.0 0.2 0.074 13.1 0.1 1.9 2 0 0 2 2 2 0 GvpH Lustrin_cystein PF14625.6 PRP88038.1 - 0.0001 22.6 10.7 0.0019 18.5 3.6 2.5 2 0 0 2 2 2 2 Lustrin, cysteine-rich repeated domain Granulin PF00396.18 PRP88038.1 - 6.4 7.2 10.1 7.4 7.0 1.3 2.7 2 0 0 2 2 2 0 Granulin ADH_zinc_N PF00107.26 PRP88039.1 - 8.4e-18 64.6 0.1 1.2e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP88039.1 - 3.1e-13 50.9 0.0 4.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP88039.1 - 0.00085 19.2 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_18 PF00704.28 PRP88040.1 - 2.2e-26 93.3 0.7 7.7e-26 91.5 0.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP88040.1 - 2e-06 28.2 7.9 2e-06 28.2 7.9 2.1 2 0 0 2 2 2 1 Chitin recognition protein FAP PF07174.11 PRP88040.1 - 0.056 12.9 13.0 0.084 12.3 13.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Med3 PF11593.8 PRP88040.1 - 1.3 8.1 13.0 1.9 7.6 13.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SH2 PF00017.24 PRP88041.1 - 4e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 SH2 domain EF-hand_12 PF17901.1 PRP88041.1 - 0.056 13.9 0.9 5 7.7 0.9 2.2 1 1 0 1 1 1 0 EF-hand fold domain DUF5409 PF17421.2 PRP88041.1 - 0.16 12.7 0.1 0.77 10.5 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5409) Methyltransf_PK PF05891.12 PRP88042.1 - 2.3e-80 269.2 0.1 2.8e-80 269.0 0.1 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 PRP88042.1 - 6.5e-11 42.8 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP88042.1 - 2.9e-10 40.7 0.0 4.4e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP88042.1 - 9.1e-07 29.6 0.0 1.6e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP88042.1 - 3.9e-06 26.7 0.1 1.2e-05 25.2 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP88042.1 - 7.2e-06 25.9 0.0 1.7e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PRP88042.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 PRP88042.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 PRP88042.1 - 0.0043 16.2 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Spermine_synth PF01564.17 PRP88042.1 - 0.034 13.6 0.1 0.61 9.5 0.1 2.2 1 1 1 2 2 2 0 Spermine/spermidine synthase domain CMAS PF02353.20 PRP88042.1 - 0.048 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Bin3 PF06859.12 PRP88042.1 - 0.064 13.9 0.0 0.24 12.0 0.0 1.8 1 1 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Myb_DNA-binding PF00249.31 PRP88043.1 - 0.009 16.2 0.1 0.023 14.9 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 PRP88043.1 - 0.048 13.7 0.7 0.47 10.5 0.0 2.3 2 1 0 3 3 3 0 SLIDE DNA_topoisoIV PF00521.20 PRP88044.1 - 1.3e-117 393.3 0.1 2.6e-117 392.3 0.0 1.6 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 PRP88044.1 - 1.8e-42 144.7 2.2 4.4e-42 143.4 2.2 1.7 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 PRP88044.1 - 8.3e-24 84.0 0.1 1.6e-23 83.1 0.1 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 PRP88044.1 - 4.5e-13 49.7 0.0 1.2e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 PRP88044.1 - 3.4e-07 30.4 0.0 9.4e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Dicty_CTDC PF00526.18 PRP88045.1 - 6.8e-56 185.7 256.1 3.1e-09 36.5 13.7 16.5 18 1 0 18 18 18 11 Dictyostelium (slime mold) repeat PA14 PF07691.12 PRP88045.1 - 3.1e-09 36.8 0.2 5.8e-09 35.9 0.2 1.3 1 0 0 1 1 1 1 PA14 domain ETF PF01012.21 PRP88046.1 - 6.1e-43 146.8 1.6 8.8e-43 146.3 1.6 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 PRP88046.1 - 1.5e-37 127.4 0.7 1.5e-37 127.4 0.7 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain Suv3_C_1 PF18147.1 PRP88047.1 - 0.001 18.9 0.1 0.0026 17.6 0.0 1.8 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Peptidase_C1 PF00112.23 PRP88049.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease HSP90 PF00183.18 PRP88050.1 - 7.9e-90 302.2 5.9 6.7e-87 292.5 3.7 2.4 1 1 1 2 2 2 2 Hsp90 protein HATPase_c PF02518.26 PRP88050.1 - 1.4e-10 41.6 0.2 3.4e-10 40.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PRP88050.1 - 2.4e-10 40.4 0.1 6.6e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Diphthami_syn_2 PF01902.17 PRP88051.1 - 7.9e-25 87.6 0.2 6.3e-23 81.4 0.0 2.7 2 1 0 2 2 2 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 PRP88051.1 - 1.1e-24 86.8 0.0 1.5e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP DUF4817 PF16087.5 PRP88051.1 - 0.036 13.9 0.2 0.099 12.5 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Ycf66_N PF07444.11 PRP88052.1 - 0.033 14.3 1.7 0.088 12.9 1.5 1.9 2 0 0 2 2 2 0 Ycf66 protein N-terminus Tubulin PF00091.25 PRP88053.1 - 2.8e-65 220.2 0.0 7.4e-65 218.8 0.0 1.8 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PRP88053.1 - 4.7e-46 156.1 0.6 1.2e-45 154.7 0.6 1.8 1 0 0 1 1 1 1 Tubulin C-terminal domain WD40 PF00400.32 PRP88053.1 - 1.1e-08 35.6 2.7 0.1 13.5 0.1 5.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Misat_Tub_SegII PF10644.9 PRP88053.1 - 0.00031 21.0 0.0 0.0021 18.4 0.0 2.4 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Triabin PF03973.13 PRP88053.1 - 0.0045 16.9 0.4 0.011 15.6 0.4 1.6 1 0 0 1 1 1 1 Triabin ANAPC4_WD40 PF12894.7 PRP88053.1 - 0.0078 16.5 0.1 0.93 9.8 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 PRP88053.1 - 0.03 12.4 2.1 0.19 9.6 0.0 2.1 2 0 0 2 2 2 0 IKI3 family DEAD_2 PF06733.15 PRP88053.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 Tubulin_2 PF13809.6 PRP88053.1 - 0.048 12.8 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin like C2 PF00168.30 PRP88054.1 - 6.4e-08 32.8 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain COesterase PF00135.28 PRP88055.1 - 4.2e-101 339.3 0.0 6.9e-101 338.6 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP88055.1 - 2e-08 34.3 0.0 5.6e-08 32.9 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Auxin_repressed PF05564.12 PRP88055.1 - 0.19 12.4 0.9 1.5 9.5 0.1 2.2 2 0 0 2 2 2 0 Dormancy/auxin associated protein Nckap1 PF09735.9 PRP88056.1 - 3.5e-260 866.5 3.9 3.9e-260 866.3 3.9 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DUF2935 PF11155.8 PRP88056.1 - 0.0085 16.4 1.3 2.8 8.3 0.0 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF2935) AAA_6 PF12774.7 PRP88057.1 - 6.9e-168 557.7 0.0 1.1e-163 543.9 0.0 2.7 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PRP88057.1 - 1.8e-132 442.2 14.0 1.8e-132 442.2 14.0 3.5 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PRP88057.1 - 7.9e-108 359.7 0.0 8.8e-107 356.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PRP88057.1 - 6.6e-98 327.7 4.8 5.8e-97 324.6 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PRP88057.1 - 8e-89 296.5 0.0 8e-89 296.5 0.0 5.5 6 0 0 6 6 6 1 ATP-binding dynein motor region AAA_7 PF12775.7 PRP88057.1 - 1.4e-79 265.8 1.0 4.2e-72 241.4 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 PRP88057.1 - 6.5e-65 219.4 10.9 1.1e-64 218.7 10.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PRP88057.1 - 9.5e-57 191.4 0.0 2.5e-56 190.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PRP88057.1 - 1.9e-46 157.0 0.0 3.5e-43 146.5 0.0 4.1 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PRP88057.1 - 3.4e-29 101.5 1.6 8e-28 97.1 0.2 3.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PRP88057.1 - 4.6e-23 81.7 0.0 5.7e-05 23.1 0.0 5.8 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PRP88057.1 - 1.4e-19 70.2 1.5 3.9e-19 68.7 0.1 2.6 3 0 0 3 3 1 1 AAA+ lid domain AAA PF00004.29 PRP88057.1 - 1.8e-14 54.3 0.0 0.04 14.4 0.1 5.0 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 PRP88057.1 - 1.7e-07 31.2 1.1 0.00015 21.7 0.0 3.9 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PRP88057.1 - 4.3e-07 30.5 7.3 0.44 10.9 0.0 5.9 6 1 1 7 7 4 1 AAA ATPase domain AAA_22 PF13401.6 PRP88057.1 - 2.1e-06 28.1 1.1 0.066 13.5 0.0 5.2 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.22 PRP88057.1 - 1.9e-05 25.0 0.1 1 9.8 0.0 4.1 3 0 0 3 3 3 2 RNA helicase AAA_19 PF13245.6 PRP88057.1 - 9.3e-05 22.8 1.2 1.3 9.4 0.0 4.8 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 PRP88057.1 - 0.0002 21.1 0.1 1.3 8.7 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_33 PF13671.6 PRP88057.1 - 0.001 19.3 0.1 0.54 10.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 PRP88057.1 - 0.0014 19.1 0.1 0.75 10.3 0.0 4.2 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 PRP88057.1 - 0.0015 19.1 6.4 1.2 9.7 0.0 4.7 6 0 0 6 6 2 2 AAA domain PduV-EutP PF10662.9 PRP88057.1 - 0.0042 16.8 0.3 0.058 13.1 0.0 3.0 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 PRP88057.1 - 0.0064 16.4 0.2 5.3 6.9 0.1 3.4 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_28 PF13521.6 PRP88057.1 - 0.022 15.0 3.2 11 6.3 0.1 3.9 3 0 0 3 3 3 0 AAA domain Allexi_40kDa PF05549.11 PRP88057.1 - 0.023 14.2 0.1 0.023 14.2 0.1 3.2 3 1 0 3 3 3 0 Allexivirus 40kDa protein RsgA_GTPase PF03193.16 PRP88057.1 - 0.028 14.3 0.0 8.5 6.3 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase AAA_29 PF13555.6 PRP88057.1 - 0.029 14.1 0.2 25 4.7 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain DUF815 PF05673.13 PRP88057.1 - 0.03 13.5 0.0 10 5.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) NACHT PF05729.12 PRP88057.1 - 0.041 13.8 1.1 4.8 7.1 0.0 3.7 3 0 0 3 3 3 0 NACHT domain DUF853 PF05872.12 PRP88057.1 - 0.063 11.9 3.7 0.88 8.1 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) ATP-cone PF03477.16 PRP88057.1 - 0.068 13.7 0.3 2.3 8.8 0.0 3.5 3 0 0 3 3 2 0 ATP cone domain RNA_pol_A_CTD PF03118.15 PRP88057.1 - 0.092 12.5 1.5 0.68 9.7 0.0 3.0 3 0 0 3 3 2 0 Bacterial RNA polymerase, alpha chain C terminal domain T2SSE PF00437.20 PRP88057.1 - 0.11 11.6 1.6 18 4.3 0.0 3.5 4 0 0 4 4 4 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 PRP88057.1 - 0.14 11.4 0.7 7.7 5.7 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.6 PRP88057.1 - 0.19 11.4 7.8 4 7.1 0.1 3.7 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 PRP88057.1 - 0.2 11.0 0.3 0.8 9.0 0.0 2.2 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Atg14 PF10186.9 PRP88057.1 - 0.31 10.1 10.8 0.42 9.7 2.3 2.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 PRP88057.1 - 0.44 9.4 26.9 0.11 11.4 3.3 3.7 3 0 0 3 3 3 0 Spc7 kinetochore protein MetOD2 PF18548.1 PRP88057.1 - 0.44 10.7 5.9 0.14 12.3 0.1 3.2 2 0 0 2 2 1 0 Metanogen output domain 2 Baculo_PEP_C PF04513.12 PRP88057.1 - 0.57 10.2 15.4 2.4 8.2 2.5 5.6 5 1 1 6 6 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 PRP88057.1 - 2.4 8.3 20.2 4.7 7.4 2.3 2.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HrpB2 PF09487.10 PRP88057.1 - 5.8 7.4 9.1 6.7 7.2 0.6 3.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB2) R3H PF01424.22 PRP88058.1 - 5.9e-15 55.0 1.3 1.1e-14 54.2 0.3 2.0 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 PRP88058.1 - 1.5e-14 53.7 99.3 4.1e-06 26.7 13.5 12.8 12 1 0 12 12 12 7 NF-X1 type zinc finger DHHC PF01529.20 PRP88059.1 - 2.9e-27 95.4 12.6 2.9e-27 95.4 12.6 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase HNOBA PF07701.14 PRP88059.1 - 0.042 13.3 0.3 0.27 10.6 0.0 2.2 2 1 0 2 2 2 0 Heme NO binding associated DZR PF12773.7 PRP88059.1 - 3.1 7.9 8.7 5.7 7.1 8.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon KAP PF05804.12 PRP88060.1 - 1.1e-189 632.1 32.8 1e-188 628.9 31.3 1.9 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) Arm PF00514.23 PRP88060.1 - 0.0026 17.7 0.2 3.2 7.9 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PRP88060.1 - 0.0075 16.6 0.3 0.13 12.7 0.0 3.1 3 2 0 3 3 3 1 HEAT repeats HEAT PF02985.22 PRP88060.1 - 0.0083 16.3 0.0 0.068 13.5 0.0 2.7 1 0 0 1 1 1 1 HEAT repeat ApoA-II PF04711.13 PRP88060.1 - 0.011 15.9 0.0 0.035 14.3 0.0 1.9 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) APG6_N PF17675.1 PRP88060.1 - 0.57 10.7 13.7 0.17 12.4 1.7 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region RhoGAP PF00620.27 PRP88060.1 - 3.3 7.5 7.0 1.6 8.5 0.7 3.4 3 1 2 5 5 5 0 RhoGAP domain Rpp20 PF12328.8 PRP88061.1 - 8.3e-12 45.2 0.0 2.3e-06 27.6 0.0 2.2 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 PRP88061.1 - 6.3e-07 29.1 0.0 8.5e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 Alba MlaD PF02470.20 PRP88061.1 - 0.035 14.4 0.0 1.2 9.4 0.0 2.6 2 1 1 3 3 3 0 MlaD protein Pkinase_Tyr PF07714.17 PRP88062.1 - 1.9e-56 191.3 0.0 2.8e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88062.1 - 7.3e-52 176.3 0.0 1.4e-51 175.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP88062.1 - 1.9e-10 40.7 0.0 4.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain GrlR PF16518.5 PRP88062.1 - 0.076 13.0 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 T3SS negative regulator,GrlR Cbl_N3 PF02762.14 PRP88062.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Filamin PF00630.19 PRP88062.1 - 0.19 12.6 0.0 0.4 11.5 0.0 1.5 1 0 0 1 1 1 0 Filamin/ABP280 repeat BP28CT PF08146.12 PRP88063.1 - 2.7e-25 89.1 7.1 3.9e-25 88.6 0.4 4.1 3 2 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 PRP88063.1 - 8.9e-12 45.4 0.2 8.9e-12 45.4 0.2 5.8 6 1 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 PRP88063.1 - 3.1e-05 23.8 2.3 0.4 11.1 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 PRP88063.1 - 0.00052 20.3 2.4 17 5.9 0.0 5.5 6 1 0 6 6 6 1 HEAT repeats ParcG PF10274.9 PRP88063.1 - 0.016 15.4 3.5 1.1 9.3 1.4 4.5 2 1 1 3 3 3 0 Parkin co-regulated protein UME PF08064.13 PRP88063.1 - 0.59 10.1 11.9 0.35 10.8 0.1 5.4 5 1 0 5 5 5 0 UME (NUC010) domain Cnd1 PF12717.7 PRP88063.1 - 0.8 9.7 16.5 0.17 11.9 0.8 6.7 6 1 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 DUF5062 PF16691.5 PRP88064.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5062) RIBIOP_C PF04950.12 PRP88066.1 - 3.4e-112 374.6 0.0 3.4e-112 374.6 0.0 2.8 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PRP88066.1 - 9e-22 77.0 0.0 2.8e-21 75.4 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SH3_1 PF00018.28 PRP88066.1 - 5.9e-06 25.8 0.7 0.043 13.4 0.1 2.7 2 0 0 2 2 2 2 SH3 domain Methyltransf_15 PF09445.10 PRP88066.1 - 0.0037 16.9 0.3 0.084 12.4 0.0 2.5 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase NAD_binding_10 PF13460.6 PRP88066.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H-binding MbeD_MobD PF04899.12 PRP88066.1 - 0.33 11.1 7.3 2.4 8.3 3.5 2.8 1 1 1 2 2 2 0 MbeD/MobD like X8 PF07983.13 PRP88067.1 - 1.4e-38 131.5 37.1 1.1e-11 45.2 6.4 5.3 5 0 0 5 5 5 4 X8 domain CBM49 PF09478.10 PRP88067.1 - 2e-25 88.9 12.4 1.3e-14 54.3 1.7 3.2 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 Glyco_hydro_16 PF00722.21 PRP88067.1 - 7.7e-16 58.1 0.6 3.6e-15 55.9 0.6 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Suc_Fer-like PF06999.12 PRP88068.1 - 8e-36 123.8 0.0 9.2e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Mob1_phocein PF03637.17 PRP88069.1 - 2.5e-80 268.4 0.6 3e-80 268.2 0.6 1.0 1 0 0 1 1 1 1 Mob1/phocein family LeuA_dimer PF08502.10 PRP88070.1 - 0.056 13.3 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 LeuA allosteric (dimerisation) domain Pkinase PF00069.25 PRP88071.1 - 8.9e-61 205.5 0.0 1.2e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88071.1 - 4.6e-37 127.7 0.1 6.3e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP88071.1 - 6.4e-05 22.4 0.0 0.0001 21.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP88071.1 - 0.00064 19.7 0.0 0.0032 17.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP88071.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP88071.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 PRP88071.1 - 0.018 14.0 0.2 0.031 13.2 0.2 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Abi_2 PF07751.11 PRP88071.1 - 0.12 12.6 0.3 0.49 10.6 0.1 2.1 3 0 0 3 3 3 0 Abi-like protein Myb_DNA-binding PF00249.31 PRP88072.1 - 9e-05 22.6 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PRP88072.1 - 0.00057 19.7 0.4 0.0013 18.6 0.4 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Sirohm_synth_M PF14824.6 PRP88072.1 - 0.049 13.1 0.0 13 5.3 0.0 2.7 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central DUF4124 PF13511.6 PRP88072.1 - 5.6 7.4 5.5 4.8 7.6 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4124) Filamin PF00630.19 PRP88073.1 - 7.9e-164 534.1 35.1 1.1e-22 80.8 0.2 8.2 8 0 0 8 8 8 8 Filamin/ABP280 repeat Invasin_D3 PF09134.10 PRP88073.1 - 8.8e-45 151.0 23.9 7.7e-08 32.5 0.1 8.3 8 0 0 8 8 8 7 Invasin, domain 3 CH PF00307.31 PRP88073.1 - 2.8e-39 133.6 1.1 5.7e-20 71.5 0.3 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain YtkA PF13115.6 PRP88073.1 - 6.3e-16 58.8 29.9 0.17 12.5 0.8 8.5 8 0 0 8 8 8 6 YtkA-like Big_6 PF17936.1 PRP88073.1 - 3.6e-08 33.6 31.2 0.048 13.9 0.2 8.7 7 3 0 8 8 8 4 Bacterial Ig domain Glyco_hydro2_C5 PF18565.1 PRP88073.1 - 4.5e-07 29.7 16.4 0.18 11.7 0.3 6.6 6 0 0 6 6 6 3 Glycoside hydrolase family 2 C-terminal domain 5 Big_1 PF02369.16 PRP88073.1 - 8.2e-06 25.7 27.1 0.007 16.4 0.5 6.5 6 0 0 6 6 6 3 Bacterial Ig-like domain (group 1) DUF5060 PF16586.5 PRP88073.1 - 3.2e-05 24.2 0.7 43 4.6 0.0 6.7 7 0 0 7 7 7 0 Domain of unknown function (DUF5060) Y_Y_Y PF07495.13 PRP88073.1 - 0.00032 20.6 0.2 33 4.5 0.0 6.1 7 0 0 7 7 6 0 Y_Y_Y domain FixH PF05751.11 PRP88073.1 - 0.0013 18.8 4.3 6.4 6.8 0.0 6.1 7 1 1 8 8 8 1 FixH Cadherin_5 PF17892.1 PRP88073.1 - 0.0045 16.9 25.3 6.7 6.8 0.2 7.2 7 0 0 7 7 7 3 Cadherin-like domain CAMSAP_CH PF11971.8 PRP88073.1 - 0.016 15.0 0.0 0.81 9.6 0.0 2.7 2 0 0 2 2 2 0 CAMSAP CH domain CarboxypepD_reg PF13620.6 PRP88073.1 - 1.1 9.6 27.9 7.9 6.8 0.0 7.6 8 0 0 8 8 8 0 Carboxypeptidase regulatory-like domain PhnH PF05845.12 PRP88073.1 - 5.1 6.8 6.4 1.9e+02 1.7 0.0 5.0 7 0 0 7 7 7 0 Bacterial phosphonate metabolism protein (PhnH) LMBR1 PF04791.16 PRP88074.1 - 5.2e-79 266.5 21.7 6.9e-79 266.1 21.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein EMC3_TMCO1 PF01956.16 PRP88074.1 - 0.12 12.0 0.0 0.12 12.0 0.0 3.4 3 1 1 4 4 4 0 Integral membrane protein EMC3/TMCO1-like Arf PF00025.21 PRP88076.1 - 1.1e-41 142.2 0.1 1.6e-25 89.6 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 PRP88076.1 - 4.4e-08 32.8 0.3 0.0032 16.9 0.1 2.1 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PRP88076.1 - 8.9e-05 21.9 0.1 0.0019 17.6 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 PRP88076.1 - 9.6e-05 22.0 0.1 0.03 13.9 0.0 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 PRP88076.1 - 0.00078 19.7 0.1 0.23 11.7 0.1 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PRP88076.1 - 0.0025 17.9 0.4 0.56 10.3 0.1 2.1 1 1 1 2 2 2 2 50S ribosome-binding GTPase G-alpha PF00503.20 PRP88076.1 - 0.082 12.0 0.9 0.67 9.1 0.3 2.0 1 1 1 2 2 2 0 G-protein alpha subunit GTP_EFTU PF00009.27 PRP88076.1 - 0.091 12.3 0.0 2.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ACT PF01842.25 PRP88076.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 ACT domain PI3Ka PF00613.20 PRP88077.1 - 8.8e-60 201.3 0.0 1.5e-59 200.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 PRP88077.1 - 9.8e-58 195.9 0.1 2.6e-57 194.5 0.1 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 PRP88077.1 - 5.3e-22 78.2 0.1 3.3e-20 72.4 0.0 2.5 1 1 1 2 2 2 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 PRP88077.1 - 6.3e-13 48.8 0.3 4.2e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 PRP88077.1 - 0.017 14.5 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PDZ_3 PF17815.1 PRP88078.1 - 9.7e-50 168.2 0.0 2e-49 167.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 PRP88078.1 - 6.8e-23 82.2 0.4 1.5e-22 81.1 0.4 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain LIM PF00412.22 PRP88078.1 - 8.1e-23 80.4 18.6 1e-11 44.9 4.7 2.5 2 0 0 2 2 2 2 LIM domain Trypsin PF00089.26 PRP88078.1 - 3.3e-13 50.0 0.0 6.4e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PRP88078.1 - 7.1e-09 35.9 0.2 8.1e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PRP88078.1 - 0.0027 18.0 0.0 0.0087 16.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PRP88078.1 - 0.088 12.7 0.1 4 7.4 0.1 2.6 2 0 0 2 2 2 0 PDZ domain zf-RRN7 PF11781.8 PRP88078.1 - 0.34 10.6 5.2 13 5.6 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DZR PF12773.7 PRP88078.1 - 0.56 10.3 8.9 3.3 7.8 1.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon PAT1 PF09770.9 PRP88078.1 - 0.89 7.7 12.2 1.2 7.3 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 E6 PF00518.17 PRP88078.1 - 1.4 9.4 7.7 9.5 6.7 0.4 3.0 2 1 0 2 2 2 0 Early Protein (E6) zf-FCS PF06467.14 PRP88078.1 - 6 6.9 16.5 5.3 7.1 0.4 4.4 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif SAPS PF04499.15 PRP88078.1 - 8.6 5.0 14.1 13 4.4 14.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Cullin PF00888.22 PRP88079.1 - 1.1e-149 500.0 24.5 3.3e-99 333.2 12.4 2.4 2 1 1 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.9 PRP88079.1 - 2.6e-28 97.8 4.3 7.6e-28 96.3 2.0 2.8 3 0 0 3 3 3 1 Cullin protein neddylation domain Phage_rep_O PF04492.13 PRP88079.1 - 0.026 15.1 0.2 0.1 13.2 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage replication protein O HTH_27 PF13463.6 PRP88079.1 - 0.054 14.0 1.3 0.43 11.1 0.0 3.1 4 0 0 4 4 4 0 Winged helix DNA-binding domain GPS PF01825.21 PRP88080.1 - 0.13 12.8 4.9 0.3 11.7 4.9 1.7 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif HSCB_C PF07743.13 PRP88081.1 - 8e-13 48.7 3.9 8e-13 48.7 3.9 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 PRP88081.1 - 2.2e-07 30.9 0.7 5.1e-07 29.7 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4379 PF14311.6 PRP88081.1 - 0.039 14.3 0.2 0.091 13.1 0.2 1.6 1 0 0 1 1 1 0 Probable Zinc-ribbon domain ZapB PF06005.12 PRP88082.1 - 0.00016 22.0 3.7 0.00016 22.0 3.7 3.5 1 1 2 3 3 3 1 Cell division protein ZapB FERM_N PF09379.10 PRP88082.1 - 0.0091 15.9 0.0 0.7 9.9 0.0 2.5 2 0 0 2 2 2 1 FERM N-terminal domain KASH_CCD PF14662.6 PRP88082.1 - 0.021 14.7 19.3 0.095 12.5 19.3 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4472 PF14739.6 PRP88082.1 - 0.037 14.8 2.4 0.037 14.8 2.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) ubiquitin PF00240.23 PRP88082.1 - 0.047 13.4 0.0 0.93 9.3 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin family SlyX PF04102.12 PRP88082.1 - 0.057 14.0 11.8 0.96 10.1 0.1 3.8 3 1 1 4 4 3 0 SlyX Lebercilin PF15619.6 PRP88082.1 - 0.094 12.4 19.5 0.22 11.1 19.0 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 PRP88082.1 - 0.12 12.5 15.8 0.039 14.1 10.8 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 PRP88082.1 - 0.21 12.1 20.2 0.84 10.2 3.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 PRP88082.1 - 0.32 10.3 13.6 0.076 12.3 9.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 PRP88082.1 - 0.62 10.1 18.1 0.36 10.9 6.8 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding KLRAQ PF10205.9 PRP88082.1 - 0.74 10.1 15.9 0.56 10.5 5.2 2.7 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein SKA2 PF16740.5 PRP88082.1 - 0.91 9.3 11.7 2.3 8.0 9.3 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 ADIP PF11559.8 PRP88082.1 - 1.8 8.7 22.6 0.28 11.3 3.0 4.2 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 PRP88082.1 - 2 8.3 18.0 0.49 10.3 0.8 3.7 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4706 PF15797.5 PRP88082.1 - 2.2 8.9 6.5 0.39 11.3 0.5 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4706) YabA PF06156.13 PRP88082.1 - 3.7 8.2 19.1 0.35 11.5 5.4 3.4 2 1 1 3 3 2 0 Initiation control protein YabA DUF641 PF04859.12 PRP88082.1 - 5.3 7.4 14.6 1.4 9.3 0.8 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) zf-C4H2 PF10146.9 PRP88082.1 - 6.6 7.0 20.7 6 7.1 15.1 2.2 1 1 0 2 2 2 0 Zinc finger-containing protein LMBR1 PF04791.16 PRP88082.1 - 7.7 5.3 5.7 9.8 5.0 5.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GxDLY PF14607.6 PRP88083.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 N-terminus of Esterase_SGNH_hydro-type FtsJ PF01728.19 PRP88084.1 - 3.6e-06 27.2 0.1 1.7e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF2362 PF10154.9 PRP88085.1 - 1.2e-40 140.0 11.7 8.4e-37 127.3 11.8 2.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) DOMON PF03351.17 PRP88085.1 - 9.9e-31 106.6 6.3 9.5e-15 54.9 0.4 2.5 2 0 0 2 2 2 2 DOMON domain WcbI PF18588.1 PRP88085.1 - 0.14 11.7 0.2 0.27 10.8 0.2 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI Metallophos_2 PF12850.7 PRP88086.1 - 1.5e-21 77.3 0.0 1.9e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 PRP88086.1 - 7.3e-05 23.4 0.3 0.0075 16.8 0.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SNF2_N PF00176.23 PRP88087.1 - 5.3e-61 206.3 0.1 1.3e-60 205.0 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 PRP88087.1 - 5.1e-43 144.8 12.0 9.9e-15 54.2 0.9 3.8 3 0 0 3 3 3 3 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 PRP88087.1 - 1.2e-21 77.1 0.0 3.1e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 PRP88087.1 - 2.8e-12 46.4 0.7 7.6e-12 45.0 0.7 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 PRP88087.1 - 1.5e-10 41.4 0.1 1.5e-09 38.1 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1087 PF06465.13 PRP88087.1 - 1.8e-08 34.3 1.4 7.9e-08 32.2 1.4 2.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) Mtf2_C PF14061.6 PRP88087.1 - 7.8e-05 22.8 0.5 1.7 8.9 0.1 3.5 3 0 0 3 3 3 2 Polycomb-like MTF2 factor 2 SAP PF02037.27 PRP88087.1 - 0.012 15.3 0.3 0.42 10.4 0.0 2.8 2 0 0 2 2 2 0 SAP domain PHD PF00628.29 PRP88087.1 - 0.035 14.0 20.5 0.22 11.4 8.7 2.8 1 1 1 2 2 2 0 PHD-finger AAA_22 PF13401.6 PRP88087.1 - 0.063 13.6 0.0 0.27 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain GST_C_3 PF14497.6 PRP88089.1 - 5.9e-21 74.5 0.0 8.8e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP88089.1 - 1.2e-09 38.3 0.0 3e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PRP88089.1 - 1.3e-08 35.0 0.0 2.5e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP88089.1 - 0.00076 19.8 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP88089.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP88089.1 - 0.028 14.4 0.1 0.061 13.4 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase_Tyr PF07714.17 PRP88090.1 - 9.4e-60 202.1 0.0 1.4e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88090.1 - 3.4e-50 170.9 0.0 7e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain ABM PF03992.16 PRP88090.1 - 0.0015 18.6 0.0 0.0085 16.2 0.0 2.2 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Kinase-like PF14531.6 PRP88090.1 - 0.0032 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP88090.1 - 0.0047 15.8 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 PRP88090.1 - 0.013 15.2 0.1 4.8 6.7 0.0 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1556 PF07590.11 PRP88091.1 - 0.51 10.7 0.2 0.51 10.7 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1556) Laminin_G_3 PF13385.6 PRP88092.1 - 2.1e-32 112.4 0.4 2.7e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Toxin_R_bind_N PF07953.12 PRP88092.1 - 0.0013 18.5 3.0 1.2 8.8 0.2 3.2 2 2 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding Pkinase_Tyr PF07714.17 PRP88093.1 - 2.5e-66 223.6 0.0 4.6e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88093.1 - 3.4e-47 161.0 0.0 5.5e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ABC_tran PF00005.27 PRP88093.1 - 2.2e-11 44.4 0.0 8e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PRP88093.1 - 2.9e-06 27.3 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system dCache_1 PF02743.18 PRP88093.1 - 3.1e-05 23.9 0.0 0.00057 19.7 0.0 2.4 2 0 0 2 2 2 1 Cache domain Kdo PF06293.14 PRP88093.1 - 0.00083 18.8 0.0 0.0028 17.0 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP88093.1 - 0.0026 16.8 0.0 0.011 14.7 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain MFS_1 PF07690.16 PRP88093.1 - 0.031 13.2 0.3 0.86 8.5 0.0 2.3 2 0 0 2 2 2 0 Major Facilitator Superfamily Pkinase_fungal PF17667.1 PRP88093.1 - 0.14 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SMC_N PF02463.19 PRP88093.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Renin_r PF07850.14 PRP88093.1 - 0.21 12.2 0.8 16 6.2 0.1 2.6 1 1 1 2 2 2 0 Renin receptor-like protein ABC2_membrane_3 PF12698.7 PRP88094.1 - 1.2e-11 44.4 13.2 1.6e-11 43.9 13.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 PRP88094.1 - 0.0002 21.9 0.1 0.00033 21.2 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 PRP88094.1 - 0.0063 16.2 0.2 0.0063 16.2 0.2 2.7 3 1 0 3 3 3 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP88094.1 - 0.14 12.6 0.2 0.24 11.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.20 PRP88095.1 - 0.078 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin GATA PF00320.27 PRP88096.1 - 1.1e-05 24.9 2.0 2.1e-05 24.0 2.0 1.5 1 0 0 1 1 1 1 GATA zinc finger Pkinase_Tyr PF07714.17 PRP88097.1 - 1.3e-72 244.2 0.0 2.6e-72 243.2 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88097.1 - 1.8e-46 158.6 0.0 3.2e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP88097.1 - 5.1e-29 99.8 75.9 2.8e-06 27.0 0.6 13.6 9 4 4 13 13 13 10 Leucine rich repeat LRR_4 PF12799.7 PRP88097.1 - 9.8e-28 95.8 88.4 0.00035 20.9 1.8 17.4 13 5 6 19 19 19 10 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 PRP88097.1 - 5.9e-10 39.1 8.5 1.2e-09 38.1 8.5 1.5 1 0 0 1 1 1 1 MYND finger LRR_1 PF00560.33 PRP88097.1 - 1.4e-08 34.1 77.7 1.8 9.4 0.1 21.4 22 2 0 22 22 22 4 Leucine Rich Repeat LRR_6 PF13516.6 PRP88097.1 - 2.1e-08 33.6 57.7 0.95 9.7 0.1 19.3 21 0 0 21 21 21 3 Leucine Rich repeat NUMOD1 PF07453.13 PRP88097.1 - 0.074 13.3 1.1 20 5.6 0.2 3.3 2 0 0 2 2 2 0 NUMOD1 domain Kinase-like PF14531.6 PRP88097.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Ion_trans_2 PF07885.16 PRP88098.1 - 1.1e-11 44.5 1.8 1.1e-11 44.5 1.8 3.2 2 1 0 2 2 2 1 Ion channel BK_channel_a PF03493.18 PRP88098.1 - 5e-11 42.6 0.0 3.5e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit TrkA_C PF02080.21 PRP88098.1 - 0.13 12.1 0.1 3.2 7.7 0.0 2.6 3 0 0 3 3 3 0 TrkA-C domain SNF2_N PF00176.23 PRP88099.1 - 2.6e-68 230.3 0.2 4.1e-68 229.7 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP88099.1 - 1.5e-21 76.8 0.0 4.4e-20 72.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP88099.1 - 8.4e-11 42.2 2.0 2.2e-10 40.8 0.0 2.6 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PRP88099.1 - 6.9e-10 38.6 0.1 6.9e-10 38.6 0.1 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 PRP88099.1 - 4e-07 30.0 0.0 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 PRP88099.1 - 0.0021 18.4 0.7 0.0021 18.4 0.7 2.6 3 0 0 3 3 3 1 DNA-binding domain COG4 PF08318.12 PRP88099.1 - 0.029 13.4 3.7 0.052 12.6 3.7 1.3 1 0 0 1 1 1 0 COG4 transport protein ERCC3_RAD25_C PF16203.5 PRP88099.1 - 0.036 13.3 0.0 0.11 11.7 0.0 1.8 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase eIF2_C PF09173.11 PRP88100.1 - 2.8e-38 130.1 0.7 7.6e-38 128.7 0.7 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 PRP88100.1 - 5.1e-23 81.6 0.5 4.3e-22 78.6 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PRP88100.1 - 2.1e-12 47.3 0.8 5e-12 46.0 0.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PRP88100.1 - 0.0016 18.5 0.0 0.0039 17.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP88100.1 - 0.002 18.0 0.4 0.024 14.5 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 PRP88100.1 - 0.0048 16.7 2.4 0.11 12.2 0.2 3.2 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 PRP88100.1 - 0.018 15.1 0.3 0.038 14.0 0.3 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Pkinase_Tyr PF07714.17 PRP88101.1 - 9e-68 228.3 0.0 2.1e-67 227.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88101.1 - 3.3e-49 167.6 0.0 5.5e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Lipase_3 PF01764.25 PRP88101.1 - 3.2e-34 117.8 0.0 6.6e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Kdo PF06293.14 PRP88101.1 - 4.6e-05 22.9 0.0 8.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.7 PRP88101.1 - 0.00063 20.4 0.0 0.0022 18.6 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Haspin_kinase PF12330.8 PRP88101.1 - 0.00079 18.5 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Hydrolase_4 PF12146.8 PRP88101.1 - 0.0014 17.9 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Pkinase_fungal PF17667.1 PRP88101.1 - 0.0063 15.3 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase dCache_1 PF02743.18 PRP88101.1 - 0.015 15.1 0.1 0.027 14.3 0.1 1.6 1 1 0 1 1 1 0 Cache domain DUF2974 PF11187.8 PRP88101.1 - 0.016 14.7 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RIO1 PF01163.22 PRP88101.1 - 0.034 13.8 0.0 0.09 12.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 PRP88101.1 - 0.04 13.2 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Thioesterase PF00975.20 PRP88101.1 - 0.13 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain ATPase_2 PF01637.18 PRP88102.1 - 1.7e-11 44.5 0.0 4.6e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA12 PF10443.9 PRP88102.1 - 2.2e-08 33.3 1.8 1.8e-06 27.0 0.1 3.2 2 1 1 3 3 3 2 RNA12 protein IFT20 PF14931.6 PRP88102.1 - 1.5 9.0 8.6 0.2 11.8 3.4 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Clathrin PF00637.20 PRP88103.1 - 2.2e-12 47.1 27.0 0.0083 16.0 0.1 10.0 4 2 6 10 10 10 4 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 PRP88103.1 - 1.3e-11 44.6 1.1 0.65 10.3 0.0 5.9 3 2 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PRP88103.1 - 0.0015 19.3 0.6 13 6.8 0.0 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Spore_III_AB PF09548.10 PRP88103.1 - 0.052 13.7 0.8 5.4 7.1 0.0 3.1 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Thioredoxin_8 PF13905.6 PRP88103.1 - 0.054 13.8 0.1 2.2 8.6 0.1 3.3 2 0 0 2 2 2 0 Thioredoxin-like Utp13 PF08625.11 PRP88103.1 - 0.52 10.2 7.5 27 4.7 0.1 5.9 6 2 1 7 7 7 0 Utp13 specific WD40 associated domain DZR PF12773.7 PRP88103.1 - 0.73 9.9 7.3 4 7.5 7.3 2.1 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.25 PRP88104.1 - 2e-35 122.4 0.0 7.2e-35 120.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88104.1 - 4.3e-23 81.9 0.0 1e-22 80.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP88104.1 - 9.7e-16 58.2 0.2 2.6e-15 56.8 0.2 1.8 1 0 0 1 1 1 1 PH domain PAS_9 PF13426.7 PRP88104.1 - 5.9e-10 39.3 0.0 1.5e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 PRP88104.1 - 3.8e-07 30.1 0.0 1.6e-06 28.1 0.0 2.2 1 0 0 1 1 1 1 PAS fold Kinase-like PF14531.6 PRP88104.1 - 3.8e-07 29.7 0.0 7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP88104.1 - 1.3e-06 27.5 1.2 1.7e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 Fungal protein kinase PAS_8 PF13188.7 PRP88104.1 - 0.00015 21.7 0.0 0.00043 20.2 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 PRP88104.1 - 0.0026 18.0 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_7 PF12860.7 PRP88104.1 - 0.022 14.9 0.9 0.47 10.6 0.0 3.1 2 1 1 3 3 3 0 PAS fold Kdo PF06293.14 PRP88104.1 - 0.053 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family T3SS_needle_E PF08988.10 PRP88104.1 - 0.12 12.5 0.2 0.31 11.2 0.2 1.7 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Herpes_pp85 PF04637.12 PRP88104.1 - 0.18 10.2 6.8 0.28 9.5 6.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ABC_tran PF00005.27 PRP88105.1 - 1.1e-22 81.0 0.0 1.7e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 PRP88105.1 - 5.1e-17 62.0 20.8 5.1e-17 62.0 20.8 2.6 3 0 0 3 3 2 1 ABC-2 type transporter AAA_21 PF13304.6 PRP88105.1 - 0.0016 18.3 0.0 0.28 10.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PRP88105.1 - 0.0018 17.9 0.3 0.0042 16.8 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP88105.1 - 0.0023 18.5 0.0 0.0037 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 PRP88105.1 - 0.018 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein T2SSE PF00437.20 PRP88105.1 - 0.021 13.9 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 PRP88105.1 - 0.021 15.1 0.1 0.056 13.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PRP88105.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PRP88105.1 - 0.026 14.0 0.2 0.43 10.0 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PRP88105.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 PRP88105.1 - 0.035 14.0 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.6 PRP88105.1 - 0.068 13.5 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 PRP88105.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PRP88105.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 PRP88105.1 - 0.2 12.1 0.1 0.64 10.5 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 PRP88105.1 - 0.23 11.0 0.3 0.38 10.3 0.3 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NrsF PF06532.11 PRP88105.1 - 9.3 5.9 11.8 0.52 10.0 4.4 2.6 3 0 0 3 3 3 0 Negative regulator of sigma F Hydrolase_4 PF12146.8 PRP88106.1 - 5.4e-08 32.4 0.3 4.4e-05 22.9 0.0 2.5 1 1 2 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 PRP88106.1 - 0.058 13.2 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PRP88106.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.19 PRP88107.1 - 2.6e-14 53.2 0.2 3.2e-13 49.6 0.2 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PRP88107.1 - 0.00074 18.9 0.1 0.0014 17.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PRP88107.1 - 0.00079 18.7 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP88107.1 - 0.0019 17.9 0.1 1.2 8.7 0.0 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP88107.1 - 0.0085 16.3 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain M20_dimer PF07687.14 PRP88107.1 - 0.041 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase dimerisation domain GCK PF07802.11 PRP88108.1 - 0.035 14.5 0.2 0.048 14.1 0.2 1.2 1 0 0 1 1 1 0 GCK domain CX9C PF16860.5 PRP88108.1 - 0.038 14.0 1.4 0.27 11.3 1.4 1.9 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF4118 PF13493.6 PRP88109.1 - 0.074 12.9 0.9 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) MMADHC PF10229.9 PRP88110.1 - 1.2e-41 143.3 0.1 1.4e-41 143.0 0.1 1.0 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein DUF2205 PF10224.9 PRP88111.1 - 2.8e-11 43.3 1.0 3.5e-11 42.9 1.0 1.1 1 0 0 1 1 1 1 Short coiled-coil protein DASH_Dad4 PF08650.10 PRP88111.1 - 0.015 15.2 0.3 0.021 14.8 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 CENP-H PF05837.12 PRP88111.1 - 0.025 15.0 0.7 0.027 14.9 0.7 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Glutaredoxin PF00462.24 PRP88112.1 - 1.3e-17 63.7 0.0 2.6e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin YopX PF09643.10 PRP88112.1 - 0.025 14.6 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 YopX protein Nop10p PF04135.12 PRP88113.1 - 2.7e-22 78.5 0.3 3.7e-22 78.1 0.3 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Proteasome PF00227.26 PRP88115.1 - 8.5e-32 110.2 0.0 9.3e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L25p PF01386.19 PRP88116.1 - 3.8e-09 36.9 0.0 6.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L25p family WH1 PF00568.23 PRP88117.1 - 7e-18 64.6 0.0 1.1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 PRP88117.1 - 1e-13 51.4 0.1 2.4e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 PRP88117.1 - 2.1e-07 30.5 0.1 4.9e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 WH2 motif C2 PF00168.30 PRP88118.1 - 5.7e-16 58.7 0.0 9.5e-15 54.8 0.0 2.2 2 0 0 2 2 2 1 C2 domain DUF4689 PF15755.5 PRP88118.1 - 0.048 13.3 0.2 0.076 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) Cupin_8 PF13621.6 PRP88119.1 - 8.7e-11 42.0 0.0 2.6e-10 40.4 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PRP88119.1 - 0.00049 20.5 0.0 0.0052 17.2 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 PRP88119.1 - 0.00083 18.9 0.2 0.0019 17.8 0.2 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Ank_4 PF13637.6 PRP88119.1 - 0.0037 17.8 0.0 0.0083 16.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP88119.1 - 0.009 16.6 0.0 0.026 15.1 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Cupin_1 PF00190.22 PRP88119.1 - 0.022 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Cupin Ank PF00023.30 PRP88119.1 - 0.04 14.4 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Con-6 PF10346.9 PRP88120.1 - 1.6e-83 274.4 36.4 4.7e-14 52.1 0.9 6.5 6 0 0 6 6 6 6 Conidiation protein 6 KGG PF10685.9 PRP88120.1 - 4.3e-07 30.0 1.6 1.2e-06 28.6 0.1 2.5 2 0 0 2 2 2 1 Stress-induced bacterial acidophilic repeat motif Arm-DNA-bind_3 PF13356.6 PRP88120.1 - 2.7e-06 27.7 11.2 7.7 7.0 0.1 6.3 4 1 2 6 6 6 1 Arm DNA-binding domain SpoIIIAH PF12685.7 PRP88120.1 - 0.0015 18.4 35.0 0.39 10.5 0.6 6.0 5 2 1 6 6 6 4 SpoIIIAH-like protein Phage_lambda_P PF06992.11 PRP88120.1 - 0.0022 17.7 12.3 0.72 9.6 0.1 4.3 4 0 0 4 4 4 2 Replication protein P DRE2_N PF16803.5 PRP88120.1 - 0.0025 18.1 0.2 47 4.2 0.0 4.4 5 0 0 5 5 5 0 Fe-S cluster assembly protein DRE2 N-terminus DUF2563 PF10817.8 PRP88120.1 - 0.016 15.8 10.4 9.2 6.9 0.1 5.3 3 1 1 6 6 6 0 Protein of unknown function (DUF2563) CotJB PF12652.7 PRP88120.1 - 0.024 14.9 1.2 5.5 7.3 0.0 3.3 3 0 0 3 3 3 0 CotJB protein Get5_C PF18514.1 PRP88120.1 - 0.035 13.8 0.5 2.9 7.7 0.0 3.3 3 0 0 3 3 3 0 Get5 C-terminal domain DicB PF05358.11 PRP88120.1 - 0.13 12.4 0.1 1.9 8.7 0.0 3.0 4 0 0 4 4 3 0 DicB protein CM_1 PF07736.11 PRP88120.1 - 0.15 12.4 1.3 44 4.5 0.0 4.0 4 0 0 4 4 4 0 Chorismate mutase type I Tox-HNH-HHH PF15637.6 PRP88120.1 - 0.19 11.9 8.6 0.32 11.2 0.3 3.2 2 1 1 3 3 3 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif PhdYeFM_antitox PF02604.19 PRP88120.1 - 0.73 9.7 13.7 4.4 7.2 0.1 5.2 6 0 0 6 6 6 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Turandot PF07240.11 PRP88120.1 - 0.79 9.7 3.3 25 4.9 0.1 3.6 2 1 1 3 3 3 0 Stress-inducible humoral factor Turandot YajC PF02699.15 PRP88120.1 - 1.1 9.2 9.3 28 4.7 0.0 3.9 4 0 0 4 4 4 0 Preprotein translocase subunit DUF1308 PF07000.11 PRP88120.1 - 1.6 8.6 5.2 15 5.5 0.1 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF1308) SRI PF08236.11 PRP88120.1 - 3.4 7.9 25.3 0.71 10.1 0.2 5.5 2 2 2 4 4 4 0 SRI (Set2 Rpb1 interacting) domain PLN_propep PF16485.5 PRP88120.1 - 4.6 7.0 14.8 53 3.6 0.1 6.0 6 0 0 6 6 6 0 Protealysin propeptide EF-hand_like PF09279.11 PRP88120.1 - 4.6 7.8 19.7 2.6 8.6 0.7 5.1 5 1 0 5 5 5 0 Phosphoinositide-specific phospholipase C, efhand-like Arrestin_C PF02752.22 PRP88121.1 - 6.8e-08 33.0 0.7 0.0003 21.2 0.1 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PRP88121.1 - 3.1e-06 27.3 0.0 7.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Lustrin_cystein PF14625.6 PRP88121.1 - 1.8e-05 25.0 25.3 0.41 11.1 0.9 4.8 2 1 2 4 4 4 4 Lustrin, cysteine-rich repeated domain DUF2680 PF10925.8 PRP88121.1 - 0.00075 19.5 3.5 0.82 9.7 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2680) F-box-like PF12937.7 PRP88121.1 - 0.043 13.7 0.3 0.13 12.1 0.3 1.9 1 0 0 1 1 1 0 F-box-like DUF19 PF01579.18 PRP88121.1 - 3.4 7.4 6.6 4.9 6.9 0.4 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF19) SH2 PF00017.24 PRP88122.1 - 1.6e-09 37.7 0.0 1.9e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 SH2 domain PAN_4 PF14295.6 PRP88122.1 - 0.0033 17.3 0.1 0.5 10.3 0.0 2.2 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 PRP88122.1 - 0.033 14.1 0.2 1.2 9.1 0.1 2.1 1 1 1 2 2 2 0 PAN domain SH2_2 PF14633.6 PRP88122.1 - 0.22 10.9 0.0 0.31 10.4 0.0 1.3 1 1 0 1 1 1 0 SH2 domain Kinesin PF00225.23 PRP88123.1 - 5.5e-111 370.7 0.1 9.3e-111 369.9 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain CH PF00307.31 PRP88123.1 - 1.4e-65 218.3 6.1 3e-20 72.4 0.1 4.9 5 0 0 5 5 5 4 Calponin homology (CH) domain Microtub_bd PF16796.5 PRP88123.1 - 5.4e-22 78.3 0.0 1.4e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding SNARE_assoc PF09335.11 PRP88123.1 - 2.8e-19 69.8 11.1 4e-18 66.0 5.6 3.3 3 0 0 3 3 3 1 SNARE associated Golgi protein CAMSAP_CH PF11971.8 PRP88123.1 - 1.3e-05 24.9 0.0 0.48 10.3 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain CH_2 PF06294.11 PRP88123.1 - 0.0039 17.3 0.2 1.3 9.2 0.0 3.4 3 0 0 3 3 3 1 CH-like domain in sperm protein Protocadherin PF08374.11 PRP88123.1 - 0.01 15.8 1.8 0.034 14.1 1.8 1.9 1 0 0 1 1 1 0 Protocadherin PAC3 PF10178.9 PRP88123.1 - 0.072 13.2 0.1 29 4.9 0.1 3.0 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 DUF1192 PF06698.11 PRP88123.1 - 0.59 10.2 3.0 29 4.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Kinesin_assoc PF16183.5 PRP88123.1 - 1.8 8.7 7.5 1.2 9.2 1.8 3.1 1 1 0 2 2 2 0 Kinesin-associated Ribosomal_L13 PF00572.18 PRP88124.1 - 9.8e-10 38.8 0.0 4.9e-08 33.3 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 DUF364 PF04016.12 PRP88124.1 - 0.13 11.8 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 Putative heavy-metal chelation DOMON PF03351.17 PRP88125.1 - 2.8e-09 37.2 0.0 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 DOMON domain Herpes_pp85 PF04637.12 PRP88125.1 - 7.9 4.8 7.9 11 4.3 7.9 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Iso_dh PF00180.20 PRP88126.1 - 1.4e-83 280.9 0.0 1.7e-83 280.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1981 PF09324.10 PRP88126.1 - 0.014 15.2 0.2 0.81 9.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Ank_2 PF12796.7 PRP88127.1 - 2.7e-08 34.3 0.0 5.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP88127.1 - 1.4e-06 28.7 0.0 8.4e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP88127.1 - 8.2e-06 26.0 0.2 6.2e-05 23.2 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88127.1 - 0.00015 21.9 0.0 0.00072 19.8 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 PRP88127.1 - 0.00036 20.8 0.0 0.0011 19.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat ORC_WH_C PF18137.1 PRP88127.1 - 2.6 8.1 6.9 14 5.7 0.2 2.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Pox_EPC_I2-L1 PF12575.8 PRP88127.1 - 4.1 7.7 5.3 2.8 8.2 0.1 3.0 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 DUF3439 PF11921.8 PRP88127.1 - 8.9 6.3 13.7 4.6 7.2 4.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GTP_cyclohydroI PF01227.22 PRP88128.1 - 3e-75 251.6 0.1 4.1e-75 251.1 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 PRP88128.1 - 0.0001 22.4 0.0 0.0009 19.3 0.0 2.2 2 0 0 2 2 2 1 QueF-like protein DUF2205 PF10224.9 PRP88129.1 - 0.0093 15.9 0.8 0.0093 15.9 0.8 2.3 2 0 0 2 2 2 1 Short coiled-coil protein DUF2937 PF11157.8 PRP88129.1 - 0.075 12.7 1.7 0.18 11.5 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) RBD-FIP PF09457.10 PRP88129.1 - 0.19 11.7 0.3 0.19 11.7 0.3 2.2 2 0 0 2 2 2 0 FIP domain GIT_CC PF16559.5 PRP88129.1 - 4.6 7.2 10.3 0.83 9.6 0.9 3.2 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ribosomal_S20p PF01649.18 PRP88129.1 - 9.4 7.0 11.5 12 6.6 0.7 3.2 2 1 1 3 3 3 0 Ribosomal protein S20 PsbP PF01789.16 PRP88130.1 - 5.2e-05 23.4 0.3 0.00013 22.1 0.1 1.8 2 0 0 2 2 2 1 PsbP DcrB PF08786.11 PRP88130.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 DcrB DUF3805 PF12712.7 PRP88130.1 - 0.0018 18.5 0.5 0.0049 17.0 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3805) CNOT1_HEAT PF16418.5 PRP88130.1 - 0.0075 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Flavodoxin_3 PF12641.7 PRP88130.1 - 0.11 12.2 0.3 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain HAT PF02184.16 PRP88131.1 - 2e-23 82.0 67.0 4.9e-15 55.2 0.1 15.7 15 2 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 PRP88131.1 - 2.2e-21 74.7 17.5 0.01 16.6 0.1 11.8 8 5 4 12 12 11 4 Tetratricopeptide repeat Suf PF05843.14 PRP88131.1 - 1.1e-18 68.3 28.3 1.2e-08 35.4 3.2 6.7 1 1 6 7 7 7 6 Suppressor of forked protein (Suf) TPR_19 PF14559.6 PRP88131.1 - 2.4e-17 63.2 1.5 0.0037 17.7 0.1 7.3 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 PRP88131.1 - 2e-10 40.0 2.1 4.7 7.7 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 PRP88131.1 - 3.3e-09 36.4 15.5 0.17 11.1 0.2 6.1 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 PRP88131.1 - 2.5e-08 33.4 21.9 0.92 9.8 0.1 9.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 PRP88131.1 - 1.7e-07 31.1 0.1 0.42 11.1 0.0 5.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP88131.1 - 1.7e-06 28.6 15.4 0.0024 18.5 0.2 6.3 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP88131.1 - 2e-05 24.8 14.8 4.8 7.6 0.0 7.9 8 2 0 8 8 8 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PRP88131.1 - 3.7e-05 23.7 23.4 0.0024 17.8 3.2 6.5 6 1 1 7 7 7 1 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 PRP88131.1 - 0.00036 21.0 17.9 10 7.0 0.1 9.7 11 0 0 11 11 9 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 PRP88131.1 - 0.00051 20.0 0.2 0.0031 17.5 0.0 2.3 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal DUF3323 PF11796.8 PRP88131.1 - 0.011 15.6 5.2 0.014 15.3 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Ebola_NP PF05505.12 PRP88131.1 - 0.021 13.2 0.1 0.032 12.6 0.1 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein MIT PF04212.18 PRP88131.1 - 0.11 12.6 16.9 3.3 7.9 0.2 6.7 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 PRP88131.1 - 0.9 9.7 20.7 22 5.4 0.1 7.7 11 0 0 11 11 9 0 Tetratricopeptide repeat bZIP_2 PF07716.15 PRP88134.1 - 0.0089 16.1 14.8 0.0089 16.1 14.8 3.4 3 1 1 4 4 4 2 Basic region leucine zipper Atg14 PF10186.9 PRP88134.1 - 2.1 7.3 19.3 0.58 9.2 16.1 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 PRP88134.1 - 2.7 8.1 24.5 0.093 12.8 15.0 3.1 3 1 0 3 3 3 0 bZIP transcription factor CheR PF01739.18 PRP88135.1 - 0.0024 17.4 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 PRP88135.1 - 0.0034 18.1 0.1 0.022 15.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP88135.1 - 0.0072 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 PRP88135.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP88135.1 - 0.014 16.0 0.0 0.03 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PMT2_N PF17987.1 PRP88135.1 - 0.017 15.3 0.1 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Methyltransf_3 PF01596.17 PRP88135.1 - 0.02 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DOT1 PF08123.13 PRP88135.1 - 0.028 14.0 0.5 0.28 10.7 0.5 2.0 1 1 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 PRP88135.1 - 0.1 13.3 0.2 0.21 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF1134 PF06577.12 PRP88136.1 - 0.071 12.9 0.0 0.083 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) Pkinase_Tyr PF07714.17 PRP88137.1 - 1.3e-82 277.0 0.1 2e-82 276.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88137.1 - 2.1e-50 171.6 0.1 3.2e-50 170.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 PRP88137.1 - 0.00038 20.1 0.2 0.00073 19.2 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PRP88137.1 - 0.00047 19.6 0.0 0.00092 18.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ECSCR PF15820.5 PRP88137.1 - 0.00051 19.8 1.9 0.0012 18.7 0.1 2.5 2 0 0 2 2 2 1 Endothelial cell-specific chemotaxis regulator Haspin_kinase PF12330.8 PRP88137.1 - 0.0016 17.5 0.3 0.0068 15.4 0.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP88137.1 - 0.015 14.1 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Amnionless PF14828.6 PRP88137.1 - 0.032 13.1 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Amnionless Globin PF00042.22 PRP88137.1 - 0.036 14.6 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 Globin EphA2_TM PF14575.6 PRP88137.1 - 0.12 13.3 0.1 0.12 13.3 0.1 1.8 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain APH PF01636.23 PRP88137.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 PRP88137.1 - 0.19 11.1 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIFIN PF02009.16 PRP88137.1 - 0.35 10.7 1.7 0.73 9.7 1.7 1.5 1 0 0 1 1 1 0 Rifin Adeno_E3_CR2 PF02439.15 PRP88137.1 - 2.3 8.1 6.5 6.5 6.6 6.5 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAO PF01266.24 PRP88139.1 - 1.7e-43 149.6 0.1 2.4e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HLH PF00010.26 PRP88139.1 - 4e-13 49.1 2.9 8e-13 48.1 2.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pyr_redox_2 PF07992.14 PRP88139.1 - 3.3e-08 33.1 0.0 0.0049 16.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP88139.1 - 5.6e-06 25.8 0.1 0.049 12.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP88139.1 - 7.4e-06 26.4 0.0 0.013 16.1 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP88139.1 - 7.1e-05 23.0 0.1 0.00018 21.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PRP88139.1 - 0.0019 17.0 0.0 1.1 7.9 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 PRP88139.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 PRP88139.1 - 0.069 12.4 0.0 0.69 9.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 PRP88139.1 - 0.071 12.4 0.7 9.3 5.5 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase Tubulin_3 PF14881.6 PRP88140.1 - 9.8e-18 64.5 0.0 1.7e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 PRP88140.1 - 3.6e-09 37.0 0.0 9.2e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF716 PF04819.12 PRP88141.1 - 0.061 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF716) Med22 PF06179.12 PRP88142.1 - 7.9e-13 48.5 2.6 1e-12 48.1 2.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex RasGEF PF00617.19 PRP88143.1 - 8.3e-42 143.4 0.0 1.7e-41 142.4 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP88143.1 - 1.4e-14 54.1 0.0 3.3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif EF-hand_4 PF12763.7 PRP88143.1 - 7.1e-10 38.8 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Ubiquitin_4 PF18036.1 PRP88144.1 - 1.5e-11 44.2 0.3 1.5e-11 44.2 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-like domain Peptidase_C58 PF03543.14 PRP88144.1 - 0.022 14.4 4.7 0.037 13.7 4.7 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen PTPRCAP PF15713.5 PRP88144.1 - 0.035 14.4 9.9 0.06 13.6 9.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 PRP88144.1 - 0.25 10.1 12.2 0.33 9.7 12.2 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 PRP88144.1 - 0.42 8.7 9.1 0.43 8.6 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 PRP88144.1 - 1.1 7.5 21.7 1.5 7.0 21.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.8 PRP88144.1 - 1.8 7.4 19.1 2.6 6.9 19.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.13 PRP88144.1 - 2.5 6.8 16.0 3.7 6.2 16.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Membralin PF09746.9 PRP88144.1 - 3.7 6.5 5.6 6.6 5.7 5.6 1.4 2 0 0 2 2 2 0 Tumour-associated protein Vfa1 PF08432.10 PRP88144.1 - 5.3 7.3 22.2 0.75 10.1 18.3 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4614 PF15391.6 PRP88144.1 - 5.5 6.9 12.6 9.9 6.1 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1084 PF06454.11 PRP88145.1 - 2e-17 63.5 14.4 3.6e-10 39.7 12.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) YoqO PF14037.6 PRP88145.1 - 0.27 11.8 16.6 0.079 13.5 7.5 2.8 2 1 0 2 2 2 0 YoqO-like protein EptA_B_N PF08019.12 PRP88145.1 - 2.9 7.8 14.4 0.092 12.6 3.4 3.2 2 1 0 3 3 3 0 Phosphoethanolamine transferase EptA/EptB YwiC PF14256.6 PRP88145.1 - 5.2 7.4 10.9 0.64 10.3 3.2 2.7 2 1 0 2 2 2 0 YwiC-like protein DUF2207 PF09972.9 PRP88145.1 - 7.7 5.2 0.0 7.7 5.2 0.0 3.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DEAD PF00270.29 PRP88150.1 - 4.6e-10 39.5 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP88150.1 - 8.7e-06 25.8 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP88150.1 - 1.9e-05 25.0 0.0 8.1e-05 22.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 PRP88150.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CLIP1_ZNF PF16641.5 PRP88150.1 - 0.067 13.1 1.4 0.17 11.8 1.4 1.8 1 0 0 1 1 1 0 CLIP1 zinc knuckle PHD PF00628.29 PRP88151.1 - 1.9e-16 59.7 23.3 4.6e-10 39.2 11.9 2.4 2 0 0 2 2 2 2 PHD-finger Zf_RING PF16744.5 PRP88151.1 - 0.0023 18.0 1.6 0.0023 18.0 1.6 3.1 2 1 0 2 2 2 1 KIAA1045 RING finger PHF12_MRG_bd PF16737.5 PRP88151.1 - 0.0053 16.5 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain PHD_2 PF13831.6 PRP88151.1 - 0.0095 15.5 10.1 0.02 14.4 3.3 2.8 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H_2 PF13832.6 PRP88151.1 - 0.017 15.3 11.4 0.026 14.7 0.9 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.22 PRP88151.1 - 0.048 13.6 16.6 0.089 12.7 2.3 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FHA PF00498.26 PRP88151.1 - 0.059 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 FHA domain zf-PHD-like PF15446.6 PRP88151.1 - 0.51 10.0 11.0 2.4 7.7 1.3 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 PRP88151.1 - 2 8.4 18.7 0.034 14.1 3.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Adaptin_N PF01602.20 PRP88152.1 - 5.6e-97 325.5 7.9 8.3e-97 324.9 7.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 PRP88152.1 - 1.4e-56 190.0 0.8 3e-56 188.9 0.1 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 PRP88152.1 - 8.6e-55 184.5 2.6 8.6e-55 184.5 2.6 2.0 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 PRP88152.1 - 1.8e-09 37.9 0.3 0.00082 19.7 0.0 5.0 3 2 3 6 6 5 2 HEAT repeats Cnd1 PF12717.7 PRP88152.1 - 1.1e-07 32.0 2.3 6.1e-05 23.1 0.0 3.0 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PRP88152.1 - 1.2e-05 25.1 0.3 0.038 14.2 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat DUF5578 PF17741.1 PRP88152.1 - 0.00059 19.3 1.4 1.6 8.0 0.0 3.1 1 1 2 3 3 3 2 Family of unknown function (DUF5578) Coatomer_g_Cpla PF16381.5 PRP88152.1 - 0.0049 17.0 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_EZ PF13513.6 PRP88152.1 - 0.011 16.2 0.1 11 6.7 0.0 4.7 4 1 1 5 5 5 0 HEAT-like repeat Alpha_adaptinC2 PF02883.20 PRP88152.1 - 0.021 15.1 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 Adaptin C-terminal domain Arm PF00514.23 PRP88152.1 - 0.11 12.6 0.6 14 5.9 0.2 3.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Mucin_bdg PF03272.13 PRP88152.1 - 0.17 11.9 0.6 1.9 8.5 0.0 2.8 3 0 0 3 3 3 0 Putative mucin or carbohydrate-binding module DUF4883 PF16224.5 PRP88152.1 - 3.8 7.8 6.9 1.7 8.9 0.1 2.9 2 1 1 3 3 3 0 DOmain of unknown function (DUF4883) RhoGAP PF00620.27 PRP88153.1 - 7.7e-45 152.4 0.0 1.8e-44 151.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 PRP88153.1 - 1.4e-20 73.8 2.7 9.7e-13 48.5 0.2 2.7 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 PRP88153.1 - 0.019 15.3 0.3 3.7 7.9 0.1 3.0 2 1 1 3 3 3 0 Pleckstrin homology domain DUF1664 PF07889.12 PRP88153.1 - 0.048 13.7 2.8 0.099 12.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PH_8 PF15409.6 PRP88153.1 - 0.068 13.5 3.4 0.15 12.4 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain DivIC PF04977.15 PRP88153.1 - 0.086 12.6 1.7 0.22 11.3 1.7 1.6 1 0 0 1 1 1 0 Septum formation initiator MCU PF04678.13 PRP88153.1 - 0.12 12.4 2.4 0.19 11.8 1.4 2.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter PH_11 PF15413.6 PRP88153.1 - 0.43 11.0 10.9 0.39 11.2 0.2 3.7 3 1 0 3 3 3 0 Pleckstrin homology domain CENP-Q PF13094.6 PRP88153.1 - 2.3 8.4 9.6 2.1 8.6 8.0 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_lid_2 PF17863.1 PRP88154.1 - 6.6e-09 35.5 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 PRP88154.1 - 0.0079 16.1 0.1 0.021 14.7 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Myb_DNA-bind_7 PF15963.5 PRP88155.1 - 8.4e-05 22.4 0.3 0.00018 21.3 0.3 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 PRP88155.1 - 0.0025 17.9 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mito_carr PF00153.27 PRP88156.1 - 2.3e-58 194.1 0.9 1.3e-19 69.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M28 PF04389.17 PRP88158.1 - 6.2e-22 78.3 0.1 8.8e-22 77.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 PRP88158.1 - 8.8e-07 28.8 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MBOAT PF03062.19 PRP88159.1 - 4.9e-47 161.0 0.3 4.9e-47 161.0 0.3 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family ThiW PF09512.10 PRP88159.1 - 0.034 14.2 2.5 0.11 12.7 1.5 2.3 2 0 0 2 2 2 0 Thiamine-precursor transporter protein (ThiW) Methyltransf_25 PF13649.6 PRP88160.1 - 2.9e-08 34.3 0.0 6.1e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PRP88160.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP88160.1 - 7.2e-05 23.4 0.0 0.00017 22.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PRP88160.1 - 0.00027 20.7 0.2 0.00072 19.4 0.0 1.8 1 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 PRP88160.1 - 0.00043 20.2 0.0 0.00073 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PRP88160.1 - 0.0029 17.0 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PRP88160.1 - 0.0076 17.0 0.0 0.02 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 PRP88160.1 - 0.0077 17.2 0.0 0.02 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRNT PF15174.6 PRP88160.1 - 0.02 14.9 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 Prion-related protein testis-specific GCD14 PF08704.10 PRP88160.1 - 0.041 13.6 0.2 0.086 12.5 0.0 1.6 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.20 PRP88160.1 - 0.045 13.0 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase XRN_N PF03159.18 PRP88161.1 - 8.3e-97 323.4 0.0 1.6e-96 322.4 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PRP88161.1 - 9e-91 305.0 2.9 3.2e-66 224.1 1.0 3.0 3 0 0 3 3 3 2 Xrn1 helical domain XRN1_D1 PF18332.1 PRP88161.1 - 4.5e-24 85.3 0.0 2.7e-22 79.5 0.0 3.0 2 1 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 PRP88161.1 - 3.3e-13 49.5 0.0 8e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain R3H PF01424.22 PRP88161.1 - 1.6e-09 37.6 0.0 4.9e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 R3H domain XRN1_D2_D3 PF18334.1 PRP88161.1 - 0.00011 22.3 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain Phospholip_A2_1 PF00068.19 PRP88161.1 - 0.00016 22.1 0.0 0.00032 21.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase A2 Pns11_12 PF17464.2 PRP88161.1 - 7.5 6.2 8.6 15 5.2 8.6 1.4 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Virul_fac_BrkB PF03631.15 PRP88162.1 - 0.029 14.0 0.2 0.033 13.8 0.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DER1 PF04511.15 PRP88163.1 - 4.7e-54 183.2 11.3 5.4e-54 183.0 11.3 1.0 1 0 0 1 1 1 1 Der1-like family EIF_2_alpha PF07541.12 PRP88164.1 - 2.9e-28 98.3 0.0 7.4e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 PRP88164.1 - 5.3e-09 36.3 2.1 1.1e-08 35.2 0.0 2.5 3 0 0 3 3 3 1 S1 RNA binding domain zf-RING_2 PF13639.6 PRP88165.1 - 0.00056 20.2 7.6 0.0014 18.9 7.6 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP88165.1 - 0.0025 17.6 7.0 0.0053 16.6 7.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP88165.1 - 0.0056 16.5 6.8 0.0096 15.8 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP88165.1 - 0.051 13.9 6.0 0.32 11.3 6.0 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PRP88165.1 - 0.091 12.8 0.5 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PRP88165.1 - 0.1 12.5 6.0 3.1 7.7 1.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PRP88165.1 - 0.2 11.4 11.0 0.19 11.5 5.9 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 PRP88165.1 - 0.24 11.5 4.6 0.16 12.0 1.2 2.2 1 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP88165.1 - 0.28 11.1 6.0 2.7 7.9 6.3 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UBZ_FAAP20 PF15750.5 PRP88165.1 - 0.52 10.3 2.8 15 5.6 0.6 2.7 2 1 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-RING_5 PF14634.6 PRP88165.1 - 0.54 10.3 4.4 3.3 7.7 2.1 2.2 2 0 0 2 2 2 0 zinc-RING finger domain Zeta_toxin PF06414.12 PRP88167.1 - 3.3e-17 62.4 0.0 3.5e-14 52.6 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin CoaE PF01121.20 PRP88167.1 - 0.015 14.9 0.0 0.54 9.9 0.0 2.5 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_18 PF13238.6 PRP88167.1 - 0.084 13.4 0.1 0.47 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3464 PF11947.8 PRP88168.1 - 0.078 12.7 0.7 0.13 12.1 0.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2054 PF10218.9 PRP88169.1 - 2.3e-33 115.1 17.0 3e-33 114.7 17.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) Zn_Tnp_IS1 PF03811.13 PRP88169.1 - 0.021 14.5 8.0 0.065 13.0 8.0 1.9 1 0 0 1 1 1 0 InsA N-terminal domain Pkinase_Tyr PF07714.17 PRP88170.1 - 4.4e-70 235.9 0.0 6.5e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88170.1 - 2e-49 168.3 0.0 3e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP88170.1 - 8.2e-40 134.4 123.5 3e-06 26.9 3.7 15.6 9 5 4 15 15 15 15 Leucine rich repeat LRR_4 PF12799.7 PRP88170.1 - 9.5e-36 121.2 130.2 2.9e-05 24.4 4.8 18.4 12 5 10 22 22 22 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP88170.1 - 1.1e-09 37.5 88.4 0.3 11.8 0.1 23.7 23 5 0 23 23 23 5 Leucine Rich Repeat LRR_6 PF13516.6 PRP88170.1 - 5.2e-05 23.0 88.5 0.35 11.0 1.1 21.9 26 0 0 26 26 26 4 Leucine Rich repeat Kdo PF06293.14 PRP88170.1 - 0.00073 19.0 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP88170.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 PRP88170.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PMP1_2 PF08114.11 PRP88170.1 - 0.28 10.9 5.1 0.63 9.8 5.1 1.5 1 0 0 1 1 1 0 ATPase proteolipid family CLU PF13236.6 PRP88174.1 - 7.7e-58 195.9 0.0 2.3e-57 194.3 0.0 1.8 2 0 0 2 2 2 1 Clustered mitochondria TPR_12 PF13424.6 PRP88174.1 - 1.1e-56 189.1 13.6 9.2e-19 67.5 0.1 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 PRP88174.1 - 4.7e-42 140.7 14.4 6.4e-07 29.0 0.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 PRP88174.1 - 8.7e-19 66.1 18.1 0.00051 20.0 0.2 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 PRP88174.1 - 1.7e-18 65.2 14.6 0.0039 17.3 0.4 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 PRP88174.1 - 5.8e-18 63.5 18.3 0.0022 17.9 0.2 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 PRP88174.1 - 8.4e-16 57.0 17.6 8.2e-06 25.4 0.2 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat SH2 PF00017.24 PRP88174.1 - 1.4e-15 57.1 0.0 3.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain TPR_MalT PF17874.1 PRP88174.1 - 9.3e-12 45.0 8.6 1e-05 25.1 0.2 3.4 1 1 2 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 PRP88174.1 - 8.2e-10 38.7 12.9 0.081 13.8 0.2 6.8 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP88174.1 - 8.6e-10 38.3 0.4 0.04 14.3 0.2 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP88174.1 - 1.4e-07 31.9 8.8 0.37 11.3 0.0 5.8 1 1 6 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 PRP88174.1 - 7.6e-07 29.7 9.0 0.034 14.8 1.1 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 PRP88174.1 - 4.1e-06 26.9 0.5 3.8e-05 23.8 0.1 2.4 1 1 1 2 2 2 1 Translation initiation factor eIF3 subunit 135 ANAPC3 PF12895.7 PRP88174.1 - 1.3e-05 25.3 10.7 0.1 12.8 0.5 5.4 5 2 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 PRP88174.1 - 1.6e-05 25.1 0.8 0.68 10.7 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.20 PRP88174.1 - 0.0058 16.8 1.2 8.6 6.9 0.0 4.8 6 0 0 6 6 3 0 PPR repeat DUF2225 PF09986.9 PRP88174.1 - 0.006 16.3 2.0 0.027 14.2 0.4 2.5 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 PRP88174.1 - 0.0083 16.2 5.6 6.2 7.0 0.2 4.5 2 2 1 4 4 4 1 MIT (microtubule interacting and transport) domain SNAP PF14938.6 PRP88174.1 - 0.0092 15.4 0.4 0.24 10.8 0.1 2.4 1 1 1 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 PRP88174.1 - 0.01 16.4 13.9 0.89 10.3 0.1 5.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 PRP88174.1 - 0.012 15.1 1.0 0.39 10.1 0.0 2.9 2 1 0 3 3 3 0 Coatomer epsilon subunit TPR_15 PF13429.6 PRP88174.1 - 0.018 14.3 0.8 4.9 6.3 0.4 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 PRP88174.1 - 0.023 14.2 4.0 1.2 8.5 0.1 3.1 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.6 PRP88174.1 - 0.041 13.6 12.2 0.95 9.2 0.2 5.5 5 1 1 6 6 5 0 TPR repeat Clathrin PF00637.20 PRP88174.1 - 0.11 12.4 0.3 5.3 6.9 0.0 2.7 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_20 PF14561.6 PRP88174.1 - 0.29 11.5 3.2 20 5.6 0.1 4.8 3 2 2 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 PRP88174.1 - 0.74 9.3 5.9 0.26 10.8 0.3 3.0 3 0 0 3 3 3 0 SHNi-TPR Pkinase_Tyr PF07714.17 PRP88175.1 - 1.2e-78 264.0 0.3 1.2e-78 264.0 0.3 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88175.1 - 7.2e-43 146.9 2.2 1.2e-42 146.1 0.1 2.5 2 0 0 2 2 2 1 Protein kinase domain LAG1-DNAbind PF09271.11 PRP88176.1 - 0.016 15.9 0.0 0.022 15.4 0.0 1.3 1 0 0 1 1 1 0 LAG1, DNA binding Coatomer_g_Cpla PF16381.5 PRP88177.1 - 0.027 14.6 0.4 0.079 13.1 0.4 1.8 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform DUF2026 PF09641.10 PRP88177.1 - 0.041 13.5 0.7 0.12 12.0 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2026) DUF743 PF05332.11 PRP88177.1 - 0.77 9.8 3.7 0.67 10.0 0.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF743) Acetyltransf_11 PF13720.6 PRP88177.1 - 5.3 7.6 5.6 1.9 9.0 1.4 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 MFS_1 PF07690.16 PRP88178.1 - 9.8e-30 103.6 41.3 5.8e-24 84.7 26.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP88178.1 - 9.8e-06 24.7 7.4 9.8e-06 24.7 7.4 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter YqaJ PF09588.10 PRP88179.1 - 0.007 16.5 1.3 0.0079 16.4 0.2 1.6 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain PDDEXK_1 PF12705.7 PRP88179.1 - 0.023 14.6 1.2 0.035 14.0 0.5 1.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily ATLF PF07737.11 PRP88179.1 - 0.22 10.8 8.4 1.6 8.0 0.8 2.5 3 0 0 3 3 3 0 Anthrax toxin lethal factor, N- and C-terminal domain DUF1319 PF07028.11 PRP88179.1 - 0.77 10.0 9.3 0.67 10.2 6.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) SH2 PF00017.24 PRP88180.1 - 2.9e-14 52.9 0.2 7.9e-14 51.5 0.0 1.8 2 1 0 2 2 2 1 SH2 domain SH2_2 PF14633.6 PRP88180.1 - 0.084 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 SH2 domain Mito_carr PF00153.27 PRP88182.1 - 3.1e-37 126.4 2.3 5e-18 64.8 0.0 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein K-box PF01486.17 PRP88183.1 - 0.00091 19.4 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 K-box region SMG1 PF15785.5 PRP88184.1 - 9e-53 179.6 6.4 9.3e-48 163.1 0.1 3.2 2 1 1 3 3 3 2 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 PRP88184.1 - 2.6e-46 158.5 0.0 8.6e-45 153.5 0.0 2.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 PRP88184.1 - 0.0013 19.1 17.0 0.0044 17.4 5.1 5.0 3 1 0 3 3 3 1 FKBP12-rapamycin binding domain FTO_CTD PF12934.7 PRP88184.1 - 0.011 15.5 1.9 0.072 12.9 1.9 2.5 1 0 0 1 1 1 0 FTO C-terminal domain ANAPC3 PF12895.7 PRP88184.1 - 0.075 13.3 0.0 16 5.8 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 COX5A PF02284.16 PRP88184.1 - 0.079 13.0 0.4 2 8.5 0.3 2.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va TPR_20 PF14561.6 PRP88184.1 - 0.25 11.7 4.7 0.99 9.8 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat OB_NTP_bind PF07717.16 PRP88185.1 - 7.9e-19 67.8 0.0 1.9e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PRP88185.1 - 2e-16 60.2 6.3 5.6e-16 58.8 0.0 3.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PRP88185.1 - 2.1e-13 50.6 0.4 2.6e-12 47.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RWD PF05773.22 PRP88185.1 - 2.4e-10 40.7 2.3 2.4e-10 40.7 2.3 3.2 3 0 0 3 3 3 1 RWD domain T2SSE PF00437.20 PRP88185.1 - 0.0024 17.0 0.1 0.0055 15.8 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PRP88185.1 - 0.011 15.7 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 PRP88185.1 - 0.012 15.6 0.4 0.13 12.1 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 PRP88185.1 - 0.016 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DND1_DSRM PF14709.7 PRP88185.1 - 0.045 14.0 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ABC_tran PF00005.27 PRP88185.1 - 0.057 13.9 0.2 0.057 13.9 0.2 3.1 2 1 1 3 3 3 0 ABC transporter AF-4 PF05110.13 PRP88186.1 - 0.57 8.2 24.2 0.75 7.8 24.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 PRP88186.1 - 2.2 6.9 18.9 3.1 6.5 18.9 1.2 1 0 0 1 1 1 0 Presenilin PcfK PF14058.6 PRP88186.1 - 4.6 7.5 24.5 2 8.7 2.9 2.5 2 0 0 2 2 2 0 PcfK-like protein DUF1764 PF08576.10 PRP88186.1 - 4.8 8.1 30.4 0.37 11.7 7.4 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4351 PF14261.6 PRP88191.1 - 0.26 11.4 2.1 0.41 10.7 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Integrase_H2C2 PF17921.1 PRP88192.1 - 1.9e-06 27.9 3.2 4.5e-06 26.7 3.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain DUF1924 PF09086.11 PRP88192.1 - 0.013 15.8 0.9 1.2 9.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) Arm_APC_u3 PF16629.5 PRP88192.1 - 0.05 13.2 0.2 0.07 12.7 0.2 1.1 1 0 0 1 1 1 0 Armadillo-associated region on APC WD40 PF00400.32 PRP88193.1 - 9.2e-38 127.6 24.2 1.8e-07 31.7 0.7 10.1 9 1 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP88193.1 - 6.5e-22 77.6 0.3 0.00027 21.2 0.0 6.8 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 PRP88193.1 - 1.2e-08 34.9 0.7 0.017 15.1 0.0 6.3 6 1 1 7 7 7 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 PRP88193.1 - 3e-07 29.7 6.3 0.022 13.7 0.1 4.4 3 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PRP88193.1 - 1.4e-06 28.4 0.1 0.002 18.0 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PHTB1_N PF14727.6 PRP88193.1 - 2.8e-05 23.6 0.1 0.65 9.3 0.0 4.3 3 1 0 4 4 4 1 PTHB1 N-terminus PQQ_3 PF13570.6 PRP88193.1 - 7.3e-05 23.1 0.2 2 9.0 0.0 5.6 5 1 0 5 5 5 1 PQQ-like domain BBS1 PF14779.6 PRP88193.1 - 0.00012 21.7 0.3 0.028 13.8 0.0 3.1 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 1 WD40_like PF17005.5 PRP88193.1 - 0.00019 20.8 0.1 0.63 9.3 0.0 4.5 3 2 0 3 3 3 1 WD40-like domain PD40 PF07676.12 PRP88193.1 - 0.00023 21.0 0.3 0.72 9.9 0.0 4.0 4 1 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 PRP88193.1 - 0.0012 17.6 1.2 2.2 6.8 0.1 4.0 3 2 1 4 4 4 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 PRP88193.1 - 0.0022 16.6 0.1 0.039 12.5 0.0 2.7 1 1 0 2 2 2 1 Cytochrome D1 heme domain DUF5046 PF16465.5 PRP88193.1 - 0.011 15.2 0.0 0.24 10.8 0.0 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF5046) Proteasome_A_N PF10584.9 PRP88193.1 - 0.012 15.3 0.6 20 5.0 0.0 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature BBS2_N PF14781.6 PRP88193.1 - 0.13 12.2 0.1 1.3 8.9 0.0 2.9 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal SYCE1 PF15233.6 PRP88194.1 - 0.045 13.8 0.6 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Ras PF00071.22 PRP88195.1 - 3.2e-62 208.9 1.0 1.1e-61 207.2 0.2 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP88195.1 - 1.6e-35 121.9 0.2 3.6e-35 120.8 0.2 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP88195.1 - 2.2e-17 63.1 0.0 5.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Ydr279_N PF17745.1 PRP88195.1 - 6e-10 39.2 0.2 8.9e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 PRP88195.1 - 7.5e-06 26.2 0.4 4.2e-05 23.8 0.3 2.1 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain GTP_EFTU PF00009.27 PRP88195.1 - 1.3e-05 24.8 0.5 5.9e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP88195.1 - 7e-05 22.9 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP88195.1 - 8.6e-05 22.0 0.0 0.00017 21.0 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PRP88195.1 - 0.0003 20.3 0.0 0.00061 19.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PRP88195.1 - 0.0043 17.0 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 PRP88195.1 - 0.052 14.0 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP88195.1 - 0.057 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 PRP88195.1 - 0.07 13.6 0.9 0.19 12.3 0.0 2.1 3 0 0 3 3 2 0 ABC transporter AAA_29 PF13555.6 PRP88195.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ENTH PF01417.20 PRP88196.1 - 1.9e-39 134.5 0.0 2.9e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 PRP88196.1 - 2.1e-05 23.7 0.0 2.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 ANTH domain NKAIN PF05640.14 PRP88197.1 - 0.0062 15.8 5.9 0.0062 15.8 5.9 1.7 1 1 1 2 2 2 1 Na,K-Atpase Interacting protein SafA PF17073.5 PRP88197.1 - 0.031 14.2 2.2 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Two-component-system connector protein DHHC PF01529.20 PRP88197.1 - 0.14 12.2 3.2 0.28 11.3 3.2 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase CLTH PF10607.9 PRP88198.1 - 1.3e-32 112.7 0.8 1.3e-32 112.7 0.8 2.3 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PRP88198.1 - 6.6e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 LisH Myb_DNA-bind_3 PF12776.7 PRP88198.1 - 0.016 16.2 5.5 0.071 14.1 0.9 3.2 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Baculo_PEP_C PF04513.12 PRP88198.1 - 0.049 13.7 0.8 0.23 11.5 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mig-14 PF07395.11 PRP88198.1 - 0.053 12.9 2.1 0.35 10.2 0.3 2.2 1 1 1 2 2 2 0 Mig-14 NPV_P10 PF05531.12 PRP88198.1 - 0.1 13.1 1.3 0.42 11.1 1.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_S7 PF00949.21 PRP88198.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease ApoC-I PF04691.12 PRP88198.1 - 0.12 12.3 1.1 0.62 10.0 0.2 2.5 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) T3SchapCesA PF11439.8 PRP88198.1 - 0.22 11.7 2.3 1.2 9.3 0.7 2.7 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA DUF1664 PF07889.12 PRP88198.1 - 0.81 9.7 8.1 0.18 11.8 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 PRP88198.1 - 2.4 8.2 10.5 7.6 6.6 10.5 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 PRP88198.1 - 3.8 6.7 8.4 0.69 9.1 4.1 1.8 2 0 0 2 2 2 0 TMPIT-like protein MCU PF04678.13 PRP88198.1 - 3.9 7.6 6.3 1 9.4 1.9 2.0 2 0 0 2 2 2 0 Mitochondrial calcium uniporter GvpL_GvpF PF06386.11 PRP88198.1 - 3.9 7.3 6.2 6.7 6.6 6.2 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Tho2 PF11262.8 PRP88198.1 - 5.1 6.2 13.7 0.37 9.9 6.9 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Fzo_mitofusin PF04799.13 PRP88198.1 - 7 6.2 9.2 0.53 9.8 3.0 2.2 2 1 1 3 3 3 0 fzo-like conserved region DUF2951 PF11166.8 PRP88198.1 - 7.1 6.9 10.4 44 4.4 6.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Cpn60_TCP1 PF00118.24 PRP88199.1 - 6.9e-93 311.9 16.1 1.7e-92 310.6 16.1 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family GMP_PDE_delta PF05351.11 PRP88199.1 - 2.5e-61 206.3 2.9 5.1e-61 205.3 2.9 1.5 1 0 0 1 1 1 1 GMP-PDE, delta subunit Trm112p PF03966.16 PRP88200.1 - 5.8e-15 55.6 0.1 7e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Sialidase PF02973.16 PRP88200.1 - 0.09 12.3 0.0 5.2 6.5 0.0 2.0 2 0 0 2 2 2 0 Sialidase, N-terminal domain DUF1241 PF06840.11 PRP88200.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DASH_Duo1 PF08651.10 PRP88202.1 - 0.0031 17.3 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 BK_channel_a PF03493.18 PRP88204.1 - 5.8e-22 77.7 0.1 1.8e-21 76.1 0.1 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PRP88204.1 - 4.1e-16 58.7 4.9 1.6e-15 56.8 4.9 2.1 1 0 0 1 1 1 1 Ion channel TrkA_C PF02080.21 PRP88204.1 - 0.0053 16.6 0.0 0.61 10.0 0.0 2.7 2 0 0 2 2 2 1 TrkA-C domain TrkA_N PF02254.18 PRP88204.1 - 0.012 15.9 0.0 11 6.4 0.0 3.2 2 1 1 3 3 3 0 TrkA-N domain DUF2627 PF11118.8 PRP88204.1 - 0.42 11.2 3.7 1.5 9.4 3.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) DUF5453 PF17534.2 PRP88204.1 - 5.2 7.0 11.5 10 6.0 11.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5453) Ank_2 PF12796.7 PRP88205.1 - 3.4e-08 34.0 0.1 0.018 15.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP88205.1 - 0.0023 18.5 1.9 3.1 8.5 0.0 4.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88205.1 - 0.0049 17.3 0.4 1.3e+02 3.7 0.0 5.7 5 0 0 5 5 5 0 Ankyrin repeat Ank_5 PF13857.6 PRP88205.1 - 0.034 14.5 0.0 15 6.1 0.0 4.1 2 2 2 4 4 4 0 Ankyrin repeats (many copies) DUF1678 PF07913.11 PRP88205.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) GDA1_CD39 PF01150.17 PRP88207.1 - 1.6e-76 257.7 0.0 2.4e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Podoplanin PF05808.11 PRP88207.1 - 0.00053 20.1 7.5 0.0012 19.0 7.5 1.5 1 0 0 1 1 1 1 Podoplanin DUF1180 PF06679.12 PRP88207.1 - 0.0016 18.9 2.5 0.0033 17.9 2.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Alpha_GJ PF03229.13 PRP88207.1 - 0.017 15.7 3.2 0.017 15.7 3.2 2.5 1 1 1 2 2 2 0 Alphavirus glycoprotein J DUF4366 PF14283.6 PRP88207.1 - 0.052 13.6 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RIFIN PF02009.16 PRP88207.1 - 0.11 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Rifin MGC-24 PF05283.11 PRP88207.1 - 0.34 11.4 15.1 2 8.9 15.1 2.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5362 PF17319.2 PRP88207.1 - 0.34 10.8 1.3 0.97 9.3 1.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5362) TMEM154 PF15102.6 PRP88207.1 - 0.43 10.5 15.8 6.9 6.6 15.8 2.4 1 1 0 1 1 1 0 TMEM154 protein family Gram_pos_anchor PF00746.21 PRP88207.1 - 0.65 10.0 3.5 0.33 10.9 0.6 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Macoilin PF09726.9 PRP88207.1 - 1.5 7.3 10.9 2.2 6.7 10.9 1.2 1 0 0 1 1 1 0 Macoilin family DUF4699 PF15770.5 PRP88207.1 - 2.7 7.7 12.1 4.4 7.0 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) GDPD PF03009.17 PRP88208.1 - 5.9e-09 36.0 0.0 4e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 PRP88208.1 - 2.3e-06 27.9 0.0 4.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Oxidored_q6 PF01058.22 PRP88209.1 - 6.4e-23 81.0 0.3 1.1e-22 80.3 0.3 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit tRNA-synt_1c PF00749.21 PRP88210.1 - 8.9e-113 376.3 0.2 3.1e-112 374.6 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Glyco_hydro_114 PF03537.13 PRP88210.1 - 2.8e-79 265.7 1.3 7.5e-79 264.3 1.3 1.7 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 tRNA-synt_1c_C PF03950.18 PRP88210.1 - 2.3e-44 151.3 0.0 1.9e-43 148.3 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 PRP88210.1 - 5.3e-41 140.3 0.4 1.1e-40 139.3 0.4 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 PRP88210.1 - 3.7e-12 47.0 3.3 3.7e-12 47.0 3.3 2.2 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 GatB_Yqey PF02637.18 PRP88210.1 - 0.0084 16.0 0.5 0.035 14.0 0.4 2.1 2 0 0 2 2 2 1 GatB domain tRNA-synt_1e PF01406.19 PRP88210.1 - 0.067 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 PRP88211.1 - 2e-26 92.9 0.0 2.3e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88211.1 - 3.8e-11 42.8 0.0 4.7e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP88211.1 - 0.0009 19.2 0.1 0.0014 18.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP88211.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PRP88211.1 - 0.024 13.7 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 PRP88211.1 - 0.032 13.8 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 PRP88211.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Grp7_allergen PF16984.5 PRP88211.1 - 0.072 13.1 0.0 0.092 12.8 0.0 1.1 1 0 0 1 1 1 0 Group 7 allergen Pkinase PF00069.25 PRP88212.1 - 2.1e-11 43.7 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88212.1 - 5.5e-11 42.2 0.0 8.4e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DENN PF02141.21 PRP88213.1 - 5.9e-34 117.6 0.1 1.7e-33 116.2 0.1 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PRP88213.1 - 1.7e-09 38.3 1.5 3.3e-09 37.4 0.2 2.2 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 PRP88213.1 - 0.00028 20.8 4.7 0.00065 19.6 4.7 1.7 1 0 0 1 1 1 1 dDENN domain DUF1348 PF07080.11 PRP88213.1 - 0.025 14.5 0.2 0.054 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) DAGAT PF03982.13 PRP88214.1 - 1.9e-101 338.9 0.2 2.2e-101 338.7 0.2 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase NmrA PF05368.13 PRP88215.1 - 4e-46 157.5 0.3 5.6e-46 157.0 0.3 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP88215.1 - 1.1e-11 45.0 0.1 1.5e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding MFS_1 PF07690.16 PRP88217.1 - 3.9e-33 114.8 30.5 3.9e-33 114.8 30.5 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily SWIRM PF04433.17 PRP88217.1 - 1.7e-27 95.6 0.0 4e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 PRP88217.1 - 1.5e-22 79.3 5.5 4e-22 78.0 5.5 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 PRP88217.1 - 8.2e-13 48.3 0.1 1.5e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP88217.1 - 1.6e-06 28.3 0.1 3.3e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_3 PF16498.5 PRP88217.1 - 0.67 10.2 4.4 1.9 8.8 4.4 1.8 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal Frtz PF11768.8 PRP88218.1 - 9.5e-09 34.1 0.0 8.9e-07 27.6 0.0 2.4 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz TPR_12 PF13424.6 PRP88218.1 - 0.076 13.3 0.4 1.2 9.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_primase_lrg PF04104.14 PRP88219.1 - 2.2e-79 266.6 0.1 3.3e-79 266.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Ras PF00071.22 PRP88220.1 - 6.6e-29 100.6 0.0 8.7e-14 51.4 0.0 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 PRP88220.1 - 1.8e-11 44.3 0.0 5.2e-07 29.9 0.0 2.3 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 PRP88220.1 - 0.042 13.9 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Aa_trans PF01490.18 PRP88221.1 - 6.5e-54 183.2 33.3 9.7e-54 182.6 33.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GST_N_3 PF13417.6 PRP88223.1 - 8.5e-16 58.1 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP88223.1 - 4.2e-15 55.8 0.1 7.2e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PRP88223.1 - 7.2e-15 55.1 0.1 1.2e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP88223.1 - 9.2e-06 25.8 0.0 2.2e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP88223.1 - 0.00097 19.3 0.0 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP88223.1 - 0.0037 17.3 0.0 0.0082 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PRP88223.1 - 0.0054 17.4 0.0 0.022 15.5 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 PRP88223.1 - 0.024 15.0 0.1 0.057 13.7 0.0 1.7 1 1 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PH PF00169.29 PRP88225.1 - 3.8e-09 37.0 0.7 6.6e-09 36.2 0.7 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP88225.1 - 3.6e-06 27.3 0.4 4.8e-06 26.9 0.4 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 PRP88225.1 - 0.047 13.5 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 PRP88225.1 - 0.047 14.0 0.0 0.21 11.9 0.0 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain G8 PF10162.9 PRP88226.1 - 0.014 15.4 0.2 0.032 14.3 0.2 1.7 1 0 0 1 1 1 0 G8 domain C6_DPF PF10170.9 PRP88226.1 - 0.059 13.7 0.2 0.19 12.1 0.2 1.8 1 0 0 1 1 1 0 Cysteine-rich domain CBX7_C PF17218.3 PRP88226.1 - 1.3 8.8 6.9 4.6 7.0 6.9 1.9 1 0 0 1 1 1 0 CBX family C-terminal motif ABC_membrane PF00664.23 PRP88227.1 - 1.4e-58 198.7 33.9 1.1e-33 117.1 11.2 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP88227.1 - 1.3e-51 174.7 0.1 2.2e-28 99.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 PRP88227.1 - 6e-07 29.1 2.1 0.089 12.2 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Polysacc_lyase PF14099.6 PRP88227.1 - 7.4e-07 29.2 1.4 2.6e-06 27.4 1.4 1.8 1 1 0 1 1 1 1 Polysaccharide lyase MMR_HSR1 PF01926.23 PRP88227.1 - 2.8e-05 24.1 1.5 0.052 13.6 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 PRP88227.1 - 3.8e-05 23.6 0.3 0.27 11.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PRP88227.1 - 6.9e-05 22.5 1.2 0.27 11.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PRP88227.1 - 0.00017 22.1 0.1 0.098 13.0 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PRP88227.1 - 0.001 19.3 0.4 0.57 10.4 0.1 2.8 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 PRP88227.1 - 0.0013 18.8 0.3 0.7 9.9 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 PRP88227.1 - 0.0014 19.2 1.3 0.39 11.2 0.1 2.8 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 PRP88227.1 - 0.0017 17.9 0.4 0.025 14.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 PRP88227.1 - 0.0023 17.0 0.1 0.045 12.8 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 PRP88227.1 - 0.0031 17.4 0.2 2.2 8.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 PRP88227.1 - 0.0033 17.2 2.2 0.48 10.1 0.2 3.0 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 PRP88227.1 - 0.0053 16.6 0.2 4 7.1 0.0 2.5 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Roc PF08477.13 PRP88227.1 - 0.0067 16.6 0.2 21 5.3 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 PRP88227.1 - 0.01 14.7 3.0 0.77 8.5 0.0 2.8 3 1 1 4 4 4 0 Predicted ATPase of the ABC class NACHT PF05729.12 PRP88227.1 - 0.01 15.8 0.1 0.18 11.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 PRP88227.1 - 0.011 15.4 0.0 0.28 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 PRP88227.1 - 0.013 14.7 2.1 0.22 10.6 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_7 PF12775.7 PRP88227.1 - 0.03 13.8 0.2 4.4 6.8 0.1 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_33 PF13671.6 PRP88227.1 - 0.094 12.9 0.0 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PRP88227.1 - 0.1 12.6 0.2 0.88 9.6 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 PRP88227.1 - 0.17 11.6 0.1 17 5.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PRP88227.1 - 0.22 10.8 0.5 6.9 5.9 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin tRNA_bind PF01588.20 PRP88228.1 - 2.6e-19 69.1 0.0 5.7e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain PPR PF01535.20 PRP88228.1 - 3.2e-19 67.8 0.2 0.00029 20.9 0.0 7.2 7 0 0 7 7 7 4 PPR repeat PPR_2 PF13041.6 PRP88228.1 - 4.4e-19 68.4 2.2 1.1e-07 31.9 0.0 6.2 4 2 2 6 6 6 4 PPR repeat family PPR_3 PF13812.6 PRP88228.1 - 3.5e-17 62.2 0.9 4.6e-07 29.8 0.0 5.9 1 1 6 7 7 7 5 Pentatricopeptide repeat domain PPR_long PF17177.4 PRP88228.1 - 1.8e-12 47.1 0.1 1e-05 25.0 0.0 2.9 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP88228.1 - 1e-07 31.5 0.1 8.9e-05 22.1 0.0 3.9 4 0 0 4 4 4 1 PPR repeat Clathrin PF00637.20 PRP88228.1 - 0.026 14.4 0.1 21 4.9 0.0 3.8 2 1 2 4 4 4 0 Region in Clathrin and VPS RPM2 PF08579.11 PRP88228.1 - 0.05 14.0 0.0 7 7.1 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.11 PRP88228.1 - 0.07 12.2 0.2 1.8 7.6 0.0 2.8 1 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway RPN7 PF10602.9 PRP88228.1 - 0.27 10.9 1.4 2.4 7.8 0.1 2.6 2 1 0 2 2 2 0 26S proteasome subunit RPN7 HATPase_c PF02518.26 PRP88229.1 - 1.8e-52 176.6 1.0 2.9e-25 88.9 0.1 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C1 PF00112.23 PRP88229.1 - 7.4e-43 147.2 6.9 1.5e-42 146.1 6.9 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Response_reg PF00072.24 PRP88229.1 - 6.4e-41 139.0 0.3 1.6e-21 76.6 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 PRP88229.1 - 2.1e-20 72.5 5.6 2.6e-11 43.4 0.3 2.9 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain Inhibitor_I29 PF08246.12 PRP88229.1 - 1.2e-09 38.4 0.3 8.4e-09 35.7 0.4 2.3 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) HATPase_c_2 PF13581.6 PRP88229.1 - 9.9e-08 32.0 0.1 0.027 14.4 0.0 2.9 3 0 0 3 3 3 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 PRP88229.1 - 3.5e-07 30.1 0.0 0.031 14.1 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 PRP88229.1 - 1.4e-05 24.9 0.0 0.095 12.6 0.0 2.9 2 0 0 2 2 2 2 GHKL domain Peptidase_C1_2 PF03051.15 PRP88229.1 - 0.0002 20.3 2.7 0.015 14.1 0.3 2.3 2 0 0 2 2 2 2 Peptidase C1-like family GAF_2 PF13185.6 PRP88229.1 - 0.13 12.5 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 GAF domain Pyr_redox_2 PF07992.14 PRP88230.1 - 5.5e-57 193.2 0.0 6.8e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP88230.1 - 2.7e-12 47.1 0.0 5.4e-10 39.7 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP88230.1 - 0.0038 16.5 0.0 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ERCC4 PF02732.15 PRP88231.1 - 1.5e-07 31.7 0.0 5.4e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 ERCC4 domain HTH_45 PF14947.6 PRP88231.1 - 0.0079 16.2 1.4 0.011 15.7 0.1 1.8 2 1 0 2 2 2 1 Winged helix-turn-helix HHH_8 PF14716.6 PRP88232.1 - 8e-05 22.9 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain zf-CCCH_6 PF18585.1 PRP88232.1 - 0.14 12.0 0.0 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF1003 PF06210.11 PRP88233.1 - 0.97 9.6 3.4 1.7 8.8 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) AAA_11 PF13086.6 PRP88233.1 - 1.4 8.7 6.5 1.8 8.3 6.5 1.2 1 0 0 1 1 1 0 AAA domain Comm PF15957.5 PRP88234.1 - 0.1 12.9 0.8 0.19 12.1 0.8 1.4 1 0 0 1 1 1 0 Commissureless UCH PF00443.29 PRP88236.1 - 4.4e-44 150.9 1.8 4.4e-44 150.9 1.8 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP88236.1 - 2.9e-27 96.1 0.7 2.9e-27 96.1 0.7 3.3 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.8 PRP88236.1 - 0.00011 21.3 2.6 0.00017 20.6 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) CECR6_TMEM121 PF14997.6 PRP88236.1 - 0.00087 19.2 0.2 0.062 13.1 0.0 2.7 3 0 0 3 3 3 1 CECR6/TMEM121 family ubiquitin PF00240.23 PRP88236.1 - 0.0052 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 PRP88236.1 - 0.022 15.3 0.1 0.081 13.5 0.1 2.0 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain tRNA_Me_trans PF03054.16 PRP88237.1 - 2.9e-97 325.7 0.0 3.5e-97 325.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 PRP88237.1 - 5.2e-11 42.1 0.0 3.3e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 PRP88237.1 - 4.8e-06 26.5 0.0 7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.14 PRP88237.1 - 5.5e-06 26.1 0.0 4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 PRP88237.1 - 7.3e-06 25.8 0.0 2.9e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 PP-loop family QueC PF06508.13 PRP88237.1 - 2.3e-05 24.0 0.0 0.00053 19.6 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 PRP88237.1 - 0.038 14.0 0.0 0.1 12.6 0.0 1.8 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family MJ1316 PF04457.12 PRP88237.1 - 0.045 14.5 0.1 0.1 13.3 0.1 1.6 1 0 0 1 1 1 0 MJ1316 RNA cyclic group end recognition domain Hpr_kinase_N PF02603.16 PRP88237.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase N terminus Myosin_head PF00063.21 PRP88238.1 - 9e-249 827.2 0.0 1.3e-248 826.7 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 PRP88238.1 - 9.3e-36 123.3 0.5 1.7e-35 122.4 0.5 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 PRP88238.1 - 0.00045 19.8 8.0 0.005 16.5 0.8 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 PRP88238.1 - 0.069 13.4 0.0 0.53 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PRP88238.1 - 0.099 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 PRP88238.1 - 0.14 12.5 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Metal_resist PF13801.6 PRP88238.1 - 0.3 11.3 1.3 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal resistance Ras PF00071.22 PRP88239.1 - 8.4e-55 184.8 0.0 1.2e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88239.1 - 2.8e-21 76.0 0.0 5.4e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP88239.1 - 5.3e-08 32.5 0.0 7.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Kinesin PF00225.23 PRP88240.1 - 4e-24 85.2 1.9 2.9e-23 82.3 0.0 2.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PRP88240.1 - 1.9e-14 53.9 6.6 2.8e-14 53.3 0.0 3.2 3 0 0 3 3 3 1 Microtubule binding Med9 PF07544.13 PRP88240.1 - 0.036 14.1 0.4 0.036 14.1 0.4 6.2 2 1 3 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 WbqC PF08889.11 PRP88240.1 - 0.12 12.3 9.7 0.027 14.4 5.9 1.9 2 0 0 2 2 2 0 WbqC-like protein family DUF3665 PF12427.8 PRP88241.1 - 3.1 7.6 5.2 1.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Carb_kinase PF01256.17 PRP88242.1 - 6.7e-43 146.9 0.0 8.5e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 PRP88242.1 - 0.0036 16.7 0.0 0.0056 16.1 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 PRP88242.1 - 0.075 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family TraG-D_C PF12696.7 PRP88242.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Chlorophyllase2 PF12740.7 PRP88242.1 - 0.18 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme NopRA1 PF16201.5 PRP88243.1 - 6.9e-11 42.1 7.1 3.6e-10 39.8 3.7 3.6 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 PRP88243.1 - 1.4e-07 31.2 0.1 1.4e-07 31.2 0.1 4.2 4 1 0 4 4 4 1 Ribosome 60S biogenesis N-terminal Ribosomal_S7 PF00177.21 PRP88243.1 - 0.21 11.2 1.4 1.1 8.9 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e Ras PF00071.22 PRP88244.1 - 2.7e-64 215.7 0.1 3.1e-64 215.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88244.1 - 2.4e-35 121.3 0.1 3.8e-35 120.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP88244.1 - 1.3e-15 57.3 0.0 1.7e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP88244.1 - 2.8e-08 33.4 0.1 3.2e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PRP88244.1 - 4e-05 23.6 0.1 0.26 11.2 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP88244.1 - 9.4e-05 22.5 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP88244.1 - 0.00023 20.8 0.1 0.00034 20.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 PRP88244.1 - 0.0038 17.7 0.1 0.15 12.5 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP88244.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 PRP88244.1 - 0.036 13.5 0.1 0.067 12.6 0.1 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Amidase02_C PF12123.8 PRP88244.1 - 0.055 13.2 0.0 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase TniB PF05621.11 PRP88244.1 - 0.058 12.8 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 PRP88244.1 - 0.066 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 PRP88244.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 PRP88244.1 - 0.079 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 PRP88244.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain UEV PF05743.13 PRP88245.1 - 3.2e-31 107.7 0.0 6.2e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 PRP88245.1 - 4.3e-20 71.4 0.4 1.2e-19 70.0 0.4 1.8 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.26 PRP88245.1 - 0.0031 17.2 0.0 0.0031 17.2 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme TFIIA PF03153.13 PRP88245.1 - 0.0058 16.7 23.6 0.0082 16.2 23.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PNP_UDP_1 PF01048.20 PRP88246.1 - 1.4e-06 27.7 0.0 2.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Alpha-amylase PF00128.24 PRP88250.1 - 1.1e-62 212.5 0.0 2.3e-60 204.9 0.0 2.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Pkinase PF00069.25 PRP88251.1 - 9.1e-64 215.4 0.0 1.2e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88251.1 - 2.4e-31 109.0 0.0 3.1e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP88251.1 - 0.00096 18.5 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP88251.1 - 0.001 18.4 0.1 0.0017 17.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP88251.1 - 0.016 14.2 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP88251.1 - 0.018 13.8 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PRP88251.1 - 0.15 11.7 0.2 15 5.1 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SAD_SRA PF02182.17 PRP88252.1 - 3.4e-42 143.8 0.1 7.4e-42 142.7 0.1 1.6 1 0 0 1 1 1 1 SAD/SRA domain OrsD PF12013.8 PRP88252.1 - 0.099 13.1 0.2 0.099 13.1 0.2 2.2 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D ADD_ATRX PF17981.1 PRP88252.1 - 0.14 12.1 0.3 0.28 11.1 0.3 1.5 1 0 0 1 1 1 0 Cysteine Rich ADD domain OTU PF02338.19 PRP88253.1 - 6.7e-15 55.7 0.0 1.8e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PRP88253.1 - 1.2e-05 24.9 2.1 0.0031 17.0 0.0 2.9 2 1 1 3 3 3 2 Peptidase C65 Otubain Coilin_N PF15862.5 PRP88253.1 - 9.9e-05 22.2 2.7 0.00029 20.6 0.0 2.5 2 1 0 2 2 2 1 Coilin N-terminus DUF1682 PF07946.14 PRP88253.1 - 0.24 10.6 30.6 0.84 8.8 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) AAA_23 PF13476.6 PRP88253.1 - 0.64 10.5 18.2 3.1 8.2 7.9 2.2 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.14 PRP88253.1 - 6.4 4.9 26.0 0.028 12.7 1.6 2.2 2 0 0 2 2 2 0 CDC45-like protein Methyltr_RsmB-F PF01189.17 PRP88254.1 - 8.5e-34 116.9 0.0 6.7e-32 110.8 0.0 3.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PRP88254.1 - 0.059 13.5 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase K_trans PF02705.16 PRP88255.1 - 1.8e-112 376.6 13.6 2.3e-112 376.2 13.6 1.1 1 0 0 1 1 1 1 K+ potassium transporter Transglut_core2 PF13369.6 PRP88256.1 - 2.7e-37 127.7 0.0 1.2e-36 125.6 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.7 PRP88256.1 - 9e-12 44.7 1.6 1.9e-11 43.6 1.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP88256.1 - 3.5e-09 36.3 3.2 7e-09 35.3 3.2 1.5 1 0 0 1 1 1 1 F-box domain YccV-like PF08755.11 PRP88256.1 - 0.0002 21.8 0.0 0.00063 20.2 0.0 1.9 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box_4 PF15966.5 PRP88256.1 - 0.0031 17.4 0.2 0.0077 16.1 0.2 1.6 1 0 0 1 1 1 1 F-box SH3_2 PF07653.17 PRP88256.1 - 0.0046 16.6 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Lyase_8 PF02278.18 PRP88257.1 - 6.3e-47 160.2 5.6 6.3e-47 160.2 5.6 1.7 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 PRP88257.1 - 5.6e-18 64.9 0.1 9e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 PRP88257.1 - 0.00051 20.4 0.8 0.00051 20.4 0.8 2.5 3 0 0 3 3 3 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Glyco_hydro_16 PF00722.21 PRP88258.1 - 1.4e-24 86.5 0.3 2.2e-24 85.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 PRP88258.1 - 1.4e-06 27.0 1.5 0.00098 17.6 1.3 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Carb_bind PF10645.9 PRP88258.1 - 0.00017 21.8 32.3 0.002 18.3 7.5 4.3 3 2 2 5 5 5 3 Carbohydrate binding Carb_bind PF10645.9 PRP88259.1 - 0.069 13.4 2.3 0.15 12.3 2.3 1.5 1 0 0 1 1 1 0 Carbohydrate binding DUF4651 PF15513.6 PRP88259.1 - 1.2 9.1 3.8 61 3.5 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4651) bZIP_1 PF00170.21 PRP88260.1 - 0.0045 17.1 0.8 4.5 7.5 0.1 3.1 3 0 0 3 3 3 1 bZIP transcription factor Baculo_PEP_C PF04513.12 PRP88260.1 - 0.0061 16.6 0.2 0.0091 16.0 0.2 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Mito_fiss_reg PF05308.11 PRP88260.1 - 0.0075 16.4 0.2 0.0078 16.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator HAUS-augmin3 PF14932.6 PRP88260.1 - 0.026 14.1 5.4 0.036 13.6 5.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 JIP_LZII PF16471.5 PRP88260.1 - 0.047 13.9 2.3 0.71 10.1 0.3 2.8 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II MCC-bdg_PDZ PF10506.9 PRP88260.1 - 0.051 13.6 4.2 0.11 12.5 3.9 1.7 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Bap31_Bap29_C PF18035.1 PRP88260.1 - 0.055 13.5 2.0 0.13 12.3 2.0 1.7 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Lzipper-MIP1 PF14389.6 PRP88260.1 - 0.08 13.3 2.4 0.16 12.3 2.4 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 HMMR_C PF15908.5 PRP88260.1 - 0.12 12.6 3.8 0.19 12.0 0.9 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF1635 PF07795.11 PRP88260.1 - 0.2 11.5 3.6 0.23 11.3 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Fungal_TACC PF12709.7 PRP88260.1 - 0.29 11.6 5.2 4.8 7.7 0.5 2.2 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins APG6_N PF17675.1 PRP88260.1 - 0.63 10.6 7.9 12 6.5 7.8 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region CLZ PF16526.5 PRP88260.1 - 0.68 10.3 4.9 0.94 9.9 0.4 2.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 PRP88260.1 - 0.73 10.5 4.1 16 6.2 0.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA IFP_35_N PF07334.13 PRP88260.1 - 0.81 9.8 3.1 3.3 7.8 2.9 2.0 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AAA_18 PF13238.6 PRP88262.1 - 2.6e-07 31.2 0.0 7.9e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Pecanex_C PF05041.15 PRP88262.1 - 4.3e-07 29.8 0.0 6.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) SKI PF01202.22 PRP88262.1 - 1.4e-06 28.5 0.0 5.6e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 PRP88262.1 - 5.2e-05 23.4 0.0 0.00028 21.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.18 PRP88262.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.6 PRP88262.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FBPase PF00316.20 PRP88263.1 - 7.2e-60 201.7 0.7 9.5e-60 201.3 0.7 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 PRP88263.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Inositol monophosphatase family Condensin2nSMC PF12422.8 PRP88264.1 - 8.5e-51 172.1 2.2 1.4e-50 171.4 0.1 2.6 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 PRP88264.1 - 3.9e-05 23.6 2.1 1.1 9.8 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 PRP88264.1 - 0.00013 22.3 0.5 0.29 11.6 0.0 3.3 1 1 0 2 2 2 2 HEAT repeats NEL PF14496.6 PRP88264.1 - 0.0091 15.4 0.4 3.2 7.1 0.4 2.9 2 0 0 2 2 2 2 C-terminal novel E3 ligase, LRR-interacting TAN PF11640.8 PRP88264.1 - 0.072 13.2 4.8 3.3 7.8 0.3 3.5 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Fe_hyd_lg_C PF02906.14 PRP88265.1 - 6.5e-76 255.2 0.0 2e-75 253.6 0.0 1.7 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 PRP88265.1 - 0.017 15.2 0.2 0.036 14.1 0.2 1.6 1 0 0 1 1 1 0 Iron hydrogenase small subunit FAD_syn PF06574.12 PRP88265.1 - 0.024 14.6 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 FAD synthetase TatD_DNase PF01026.21 PRP88267.1 - 3e-57 193.9 0.0 3.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Ank_2 PF12796.7 PRP88268.1 - 1.5e-68 227.4 5.8 2.1e-15 57.1 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP88268.1 - 8.9e-47 151.7 5.9 0.0006 20.1 0.1 9.3 9 0 0 9 9 9 9 Ankyrin repeat Ank PF00023.30 PRP88268.1 - 2.9e-46 153.9 16.0 7.4e-05 23.0 0.1 9.3 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.6 PRP88268.1 - 7.2e-45 150.8 4.1 6e-08 33.1 0.0 7.7 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP88268.1 - 7.5e-44 147.2 15.3 2.2e-09 37.4 0.1 8.2 2 2 6 8 8 8 8 Ankyrin repeats (many copies) SNF2_N PF00176.23 PRP88270.1 - 2.1e-60 204.3 0.0 3.2e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PRP88270.1 - 6.9e-17 61.8 0.0 4.7e-16 59.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP88270.1 - 3.3e-09 37.0 0.0 9.9e-09 35.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PRP88270.1 - 0.001 18.3 0.0 0.0026 17.0 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 PRP88270.1 - 0.09 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_hydro_43 PF04616.14 PRP88272.1 - 2e-49 168.5 3.2 2.6e-49 168.1 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PAN_4 PF14295.6 PRP88272.1 - 1.8e-11 43.7 4.3 4e-11 42.6 4.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PRP88272.1 - 0.001 19.0 0.3 0.0022 17.9 0.3 1.5 1 0 0 1 1 1 1 PAN domain Myotub-related PF06602.14 PRP88274.1 - 8.4e-122 406.5 0.0 1.2e-121 405.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PH PF00169.29 PRP88274.1 - 1.7e-06 28.4 0.0 3.3e-05 24.3 0.0 3.1 3 0 0 3 3 3 1 PH domain Vps36_ESCRT-II PF11605.8 PRP88274.1 - 9.6e-05 22.5 0.0 0.00023 21.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.20 PRP88274.1 - 0.0094 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.6 PRP88274.1 - 0.044 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family KH_1 PF00013.29 PRP88274.1 - 0.21 11.5 1.2 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 KH domain DUF3430 PF11912.8 PRP88276.1 - 0.0023 18.0 4.6 0.0032 17.5 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Staphostatin_B PF09023.10 PRP88277.1 - 0.16 12.0 0.1 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Staphostatin B RabGAP-TBC PF00566.18 PRP88278.1 - 1.1e-37 129.8 4.8 1.1e-37 129.8 4.8 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SH2 PF00017.24 PRP88278.1 - 2.4e-12 46.8 0.1 8.4e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 SH2 domain SH2_2 PF14633.6 PRP88278.1 - 0.014 14.8 1.1 0.03 13.7 0.0 1.9 2 0 0 2 2 2 0 SH2 domain EF-hand_1 PF00036.32 PRP88279.1 - 1.2e-14 52.7 1.3 3.5e-07 29.3 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PRP88279.1 - 9.9e-13 46.9 0.5 2.3e-05 23.9 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP88279.1 - 1.1e-11 43.7 2.5 3.3e-06 26.3 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PRP88279.1 - 4.1e-11 43.2 2.2 1e-10 41.9 0.9 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 PRP88279.1 - 1.1e-06 28.4 2.5 1.4e-06 28.0 0.9 2.1 2 1 0 2 2 2 1 EF-hand domain pair DZR PF12773.7 PRP88280.1 - 0.0008 19.4 7.7 0.018 15.0 3.4 2.6 2 1 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 PRP88280.1 - 0.0042 16.8 13.7 0.14 12.0 1.5 3.3 3 0 0 3 3 3 2 zinc-ribbon domain zinc_ribbon_15 PF17032.5 PRP88280.1 - 0.01 16.5 2.6 0.022 15.5 2.6 1.5 1 1 0 1 1 1 0 zinc-ribbon family DUF2175 PF09943.9 PRP88280.1 - 0.082 13.2 0.0 0.082 13.2 0.0 1.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-ribbon_3 PF13248.6 PRP88280.1 - 0.11 12.0 12.2 0.65 9.5 6.6 3.1 2 1 1 3 3 3 0 zinc-ribbon domain LIM PF00412.22 PRP88280.1 - 0.11 12.7 5.3 0.13 12.5 0.1 2.5 2 1 0 2 2 2 0 LIM domain DUF2688 PF10892.8 PRP88280.1 - 0.13 11.8 4.3 0.13 11.7 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2688) Ribosomal_L37e PF01907.19 PRP88280.1 - 0.15 12.2 0.5 0.15 12.2 0.5 2.8 2 1 0 2 2 2 0 Ribosomal protein L37e Nudix_N_2 PF14803.6 PRP88280.1 - 0.18 11.8 12.7 0.32 11.0 0.3 3.2 3 0 0 3 3 3 0 Nudix N-terminal zf_UBZ PF18439.1 PRP88280.1 - 0.21 11.2 9.1 1 9.0 0.1 3.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 PRP88280.1 - 0.4 10.8 0.6 0.4 10.8 0.6 2.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-NADH-PPase PF09297.11 PRP88280.1 - 0.6 9.8 11.2 1.4 8.6 0.1 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain HscB_4_cys PF18256.1 PRP88280.1 - 0.62 9.9 7.3 30 4.6 0.5 3.2 2 1 1 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif GFA PF04828.14 PRP88280.1 - 0.66 10.4 7.9 33 4.9 0.1 3.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_9 PF14369.6 PRP88280.1 - 0.75 10.1 0.1 0.75 10.1 0.1 2.5 2 1 1 3 3 3 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 PRP88280.1 - 2.8 7.9 7.3 18 5.3 0.1 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain C1_1 PF00130.22 PRP88280.1 - 5.5 7.0 10.1 6.8 6.7 0.6 2.8 2 2 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_recom PF13408.6 PRP88280.1 - 6.3 7.4 10.0 45 4.7 0.5 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain MqsA_antitoxin PF15731.5 PRP88280.1 - 9.3 6.4 7.1 14 5.8 0.2 2.7 2 1 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA PknG_rubred PF16919.5 PRP88280.1 - 9.6 6.4 9.9 1.9 8.6 0.1 2.8 2 1 0 2 2 2 0 Protein kinase G rubredoxin domain adh_short PF00106.25 PRP88281.1 - 6.3e-45 153.0 0.0 7.9e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP88281.1 - 4.4e-24 85.3 0.0 6.2e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP88281.1 - 1.1e-10 41.7 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 PRP88281.1 - 0.0019 18.5 0.1 0.003 17.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain THF_DHG_CYH_C PF02882.19 PRP88281.1 - 0.21 10.9 0.8 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain EGF PF00008.27 PRP88282.1 - 0.14 12.5 6.1 0.18 12.2 5.2 1.6 1 1 1 2 2 2 0 EGF-like domain EGF_2 PF07974.13 PRP88282.1 - 3.5 8.1 10.1 5.5 7.4 10.1 1.3 1 0 0 1 1 1 0 EGF-like domain RhoGAP PF00620.27 PRP88283.1 - 6.2e-13 48.8 0.0 9.5e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 RhoGAP domain Glyco_hydro_cc PF11790.8 PRP88284.1 - 3.1e-39 135.0 3.4 4e-39 134.6 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Thioredoxin_7 PF13899.6 PRP88285.1 - 7.5e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PRP88285.1 - 6.4e-07 29.3 0.0 9.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 PRP88285.1 - 0.00023 21.0 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PRP88285.1 - 0.0007 20.0 0.0 0.00095 19.6 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PRP88285.1 - 0.034 14.5 0.0 0.053 13.8 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 PRP88285.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Disulph_isomer PF06491.11 PRP88285.1 - 0.19 11.8 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Disulphide isomerase Dus PF01207.17 PRP88286.1 - 6.5e-72 242.2 0.0 8.9e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 PRP88286.1 - 0.072 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Codanin-1_C PF15296.6 PRP88286.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Codanin-1 C-terminus SOR_SNZ PF01680.17 PRP88286.1 - 0.15 11.9 0.0 3 7.6 0.0 2.3 1 1 1 2 2 2 0 SOR/SNZ family Cid2 PF09774.9 PRP88287.1 - 4.1e-07 30.5 4.4 2.3e-06 28.1 4.4 2.1 1 1 0 1 1 1 1 Caffeine-induced death protein 2 COPIIcoated_ERV PF07970.12 PRP88288.1 - 2.9e-85 285.6 0.1 3.9e-85 285.2 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 PRP88288.1 - 1.2e-30 105.6 0.3 3.3e-30 104.3 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RNB PF00773.19 PRP88289.1 - 4.1e-95 318.8 0.8 8.9e-95 317.7 0.8 1.6 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PRP88289.1 - 5.2e-18 64.8 0.0 1.5e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 PRP88289.1 - 1.5e-05 24.7 0.0 3.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 PRP88289.1 - 0.0001 22.1 0.0 0.00041 20.3 0.0 2.0 1 0 0 1 1 1 1 S1 domain CSD2 PF17876.1 PRP88289.1 - 0.0013 18.8 0.1 0.66 10.2 0.0 2.6 2 0 0 2 2 2 2 Cold shock domain PIN_4 PF13638.6 PRP88289.1 - 0.0043 17.4 5.8 0.0047 17.2 0.1 3.1 3 0 0 3 3 3 1 PIN domain SF1-HH PF16275.5 PRP88289.1 - 0.98 9.8 7.2 0.45 10.9 1.4 3.0 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain DAGK_cat PF00781.24 PRP88290.1 - 1.6e-29 102.1 0.1 3.8e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain FKBP_C PF00254.28 PRP88290.1 - 2e-20 72.9 0.0 4.7e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase pPIWI_RE_Z PF18155.1 PRP88290.1 - 0.23 11.3 1.3 0.41 10.5 1.3 1.3 1 0 0 1 1 1 0 pPIWI RE three-gene island domain Z Dicty_REP PF05086.12 PRP88290.1 - 0.58 8.1 2.2 0.82 7.6 2.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3430 PF11912.8 PRP88290.1 - 9.5 6.2 13.9 0.47 10.5 7.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3430) DSBA PF01323.20 PRP88291.1 - 2e-20 73.4 0.0 2.8e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Beach PF02138.18 PRP88292.1 - 3.4e-120 400.6 0.4 1.1e-119 398.8 0.4 2.0 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 PRP88292.1 - 2.7e-15 56.3 0.5 2.2e-14 53.3 0.1 2.8 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 PRP88292.1 - 1.6e-08 34.1 0.0 1.6e-08 34.1 0.0 4.6 5 1 0 5 5 5 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 PRP88292.1 - 3.6e-08 33.7 0.0 1.1e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 PRP88292.1 - 6.1e-06 26.9 22.8 0.012 16.4 2.1 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat GRAM PF02893.20 PRP88292.1 - 0.00016 21.5 0.1 0.00048 20.0 0.1 1.8 1 0 0 1 1 1 1 GRAM domain ANAPC4_WD40 PF12894.7 PRP88292.1 - 0.00024 21.3 0.1 0.75 10.1 0.1 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DnaJ PF00226.31 PRP88293.1 - 3.3e-20 72.0 0.4 7.4e-20 70.8 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4523 PF15023.6 PRP88293.1 - 0.012 15.5 0.5 0.032 14.0 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4523) Peptidase_S15 PF02129.18 PRP88293.1 - 0.041 13.5 1.1 0.055 13.0 1.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) RR_TM4-6 PF06459.12 PRP88293.1 - 0.069 13.0 10.0 0.095 12.5 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TrwC PF08751.11 PRP88293.1 - 0.51 9.8 10.8 0.75 9.3 10.8 1.2 1 0 0 1 1 1 0 TrwC relaxase LMBR1 PF04791.16 PRP88293.1 - 1.3 7.9 2.9 1.4 7.7 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1682 PF07946.14 PRP88293.1 - 1.6 7.9 15.9 2.8 7.1 15.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Tho2 PF11262.8 PRP88293.1 - 2.3 7.4 10.1 3.8 6.6 10.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.9 PRP88293.1 - 3 6.9 12.0 4.4 6.3 12.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GBP_C PF02841.14 PRP88293.1 - 4.8 6.5 16.0 6.8 6.0 16.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF3430 PF11912.8 PRP88295.1 - 8.6e-06 25.9 8.6 1.8e-05 24.9 8.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 PRP88295.1 - 0.28 11.4 10.2 0.08 13.2 1.5 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3586) UQ_con PF00179.26 PRP88296.1 - 3.6e-54 182.2 0.0 4.3e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PRP88296.1 - 0.00047 19.9 0.0 0.00059 19.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PRP88296.1 - 0.037 14.3 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 PRP88296.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain TraI_2_C PF07515.11 PRP88296.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term Metallophos PF00149.28 PRP88297.1 - 5.6e-11 43.3 0.0 8.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Lipase_GDSL_3 PF14606.6 PRP88297.1 - 0.023 14.8 0.0 10 6.2 0.0 3.0 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family RabGAP-TBC PF00566.18 PRP88298.1 - 1.3e-47 162.2 1.8 2.8e-47 161.2 1.8 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain STAR_dimer PF16544.5 PRP88298.1 - 0.11 12.1 0.2 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein Apt1 PF10351.9 PRP88298.1 - 1.5 7.5 9.8 2.3 7.0 9.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2052 PF09747.9 PRP88298.1 - 4 7.5 7.0 3 7.9 3.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 PRP88298.1 - 5.1 6.8 7.0 8.2 6.2 7.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4139 PF13598.6 PRP88299.1 - 5.2e-46 157.0 0.1 5.2e-46 157.0 0.1 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 PRP88299.1 - 1.3e-16 60.8 2.9 1.3e-16 60.8 2.9 2.0 1 1 1 2 2 2 1 N-terminal domain of unknown function (DUF4140) Top6b_C PF18000.1 PRP88299.1 - 0.082 13.1 3.9 1.7 8.9 0.8 2.9 2 1 0 2 2 2 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain DUF4407 PF14362.6 PRP88299.1 - 0.11 11.8 3.2 0.16 11.3 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) STATa_Ig PF18214.1 PRP88301.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 STATa Immunoglobulin-like domain Rib_5-P_isom_A PF06026.14 PRP88302.1 - 5.2e-53 179.2 0.0 6.4e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 PRP88302.1 - 0.00033 20.6 0.0 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 DeoR C terminal sensor domain Sugar-bind PF04198.13 PRP88302.1 - 0.004 16.3 0.0 0.0054 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain Pkinase_Tyr PF07714.17 PRP88303.1 - 3.2e-75 252.8 0.0 4.7e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88303.1 - 2e-50 171.6 0.0 3e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP88303.1 - 2.5e-17 62.4 50.4 8.3e-07 28.7 0.2 10.9 6 3 3 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 PRP88303.1 - 3.7e-17 62.1 60.9 0.0067 16.8 0.1 12.1 7 4 7 14 14 14 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP88303.1 - 7.3e-07 28.7 39.7 0.87 9.8 0.0 13.8 16 0 0 16 16 16 3 Leucine Rich repeat LRR_1 PF00560.33 PRP88303.1 - 0.00029 20.9 46.2 2.2 9.2 0.1 14.0 12 3 1 13 13 13 2 Leucine Rich Repeat Kinase-like PF14531.6 PRP88303.1 - 0.0027 17.1 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP88303.1 - 0.02 13.7 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase CYYR1 PF10873.8 PRP88303.1 - 0.052 14.0 0.3 0.12 12.8 0.3 1.5 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Haspin_kinase PF12330.8 PRP88303.1 - 0.087 11.7 0.1 0.18 10.7 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain His_Phos_1 PF00300.22 PRP88305.1 - 1.6e-20 73.6 0.0 3.9e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4604 PF15377.6 PRP88306.1 - 1.4e-05 25.6 27.4 2.6e-05 24.7 27.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) CDC45 PF02724.14 PRP88306.1 - 0.023 13.0 14.1 0.023 13.0 14.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Striatin PF08232.12 PRP88306.1 - 0.65 10.6 14.1 0.96 10.0 14.1 1.2 1 0 0 1 1 1 0 Striatin family GAGA_bind PF06217.12 PRP88306.1 - 1.9 8.7 11.7 2.2 8.5 11.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Sec62 PF03839.16 PRP88306.1 - 8 5.9 14.9 10 5.5 14.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1206 PF06724.11 PRP88307.1 - 4.2e-16 58.8 19.0 8.1e-07 29.0 0.1 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) DUF2189 PF09955.9 PRP88307.1 - 1 9.6 6.2 3.8 7.8 0.1 2.8 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) FtsX PF02687.21 PRP88307.1 - 3.7 8.1 8.4 11 6.6 1.3 2.8 3 0 0 3 3 3 0 FtsX-like permease family Cation_ATPase_C PF00689.21 PRP88308.1 - 2.3e-09 37.2 23.1 4.6e-08 33.0 11.5 2.7 2 1 0 2 2 2 2 Cation transporting ATPase, C-terminus ProRS-C_1 PF09180.11 PRP88309.1 - 1e-23 83.3 2.4 4.6e-22 78.0 2.4 2.7 1 1 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 PRP88309.1 - 8.2e-20 71.5 0.0 1.7e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PRP88309.1 - 1.2e-14 54.2 0.0 3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain BUD22 PF09073.10 PRP88309.1 - 0.021 14.2 20.1 0.035 13.5 20.1 1.2 1 0 0 1 1 1 0 BUD22 RNA_pol_Rpc4 PF05132.14 PRP88309.1 - 1 9.8 9.7 2.6 8.5 9.7 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 PRP88309.1 - 3 6.0 14.2 4.6 5.4 14.2 1.3 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 PRP88309.1 - 3.7 6.2 11.6 5.9 5.6 11.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FancD2 PF14631.6 PRP88309.1 - 3.7 4.8 12.0 5.2 4.3 12.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease MCM_bind PF09739.9 PRP88309.1 - 6.8 5.0 11.6 10 4.4 11.6 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DEAD PF00270.29 PRP88310.1 - 1.7e-17 63.7 0.0 1.2e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP88310.1 - 1.2e-07 32.0 0.0 5.6e-07 29.9 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP88310.1 - 2.1e-07 31.1 0.0 5.7e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 PRP88310.1 - 0.00021 21.8 0.0 0.00053 20.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.6 PRP88310.1 - 0.073 13.3 0.1 0.41 10.9 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4332) DNA_pol_lambd_f PF10391.9 PRP88310.1 - 0.082 12.7 0.0 0.63 9.9 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda AAA_22 PF13401.6 PRP88310.1 - 0.19 12.0 0.2 0.83 9.9 0.2 2.1 1 1 0 1 1 1 0 AAA domain Band_7 PF01145.25 PRP88313.1 - 8.9e-18 64.9 0.2 1.2e-17 64.4 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 PRP88313.1 - 0.054 13.2 0.1 0.13 12.0 0.1 1.6 1 1 1 2 2 2 0 SPFH domain-Band 7 family GPI2 PF06432.11 PRP88314.1 - 5.7e-71 239.2 13.2 5.7e-71 239.2 13.2 1.4 2 0 0 2 2 2 1 Phosphatidylinositol N-acetylglucosaminyltransferase FA_desaturase PF00487.24 PRP88314.1 - 0.51 10.1 7.1 2.3 8.0 2.7 2.7 3 0 0 3 3 3 0 Fatty acid desaturase VWA_2 PF13519.6 PRP88315.1 - 0.00056 20.5 0.1 0.0022 18.6 0.1 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain TMA7 PF09072.10 PRP88316.1 - 1.2e-27 96.5 20.5 1.3e-27 96.4 20.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 RNA_pol_Rpc34 PF05158.12 PRP88316.1 - 0.024 14.0 0.2 0.024 14.0 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit BTB PF00651.31 PRP88317.1 - 1.1e-24 86.8 0.1 5.5e-24 84.5 0.0 2.0 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 PRP88317.1 - 3.4e-06 27.1 0.2 3.3e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch HSP70 PF00012.20 PRP88318.1 - 2.1e-238 792.4 9.7 2.5e-238 792.2 9.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP88318.1 - 4.1e-17 62.0 0.1 9.7e-16 57.5 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 PRP88318.1 - 0.00087 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HSP90 PF00183.18 PRP88319.1 - 2.8e-48 165.1 0.1 1e-37 130.2 0.0 2.0 2 0 0 2 2 2 2 Hsp90 protein DUF1731 PF08338.11 PRP88320.1 - 4e-16 58.6 0.0 1e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 PRP88320.1 - 9.4e-15 54.7 0.0 2e-14 53.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP88320.1 - 3.3e-07 30.0 0.1 5.5e-05 22.7 0.1 2.5 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PRP88320.1 - 0.00016 20.9 0.0 0.033 13.3 0.0 2.7 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 PRP88320.1 - 0.00032 20.6 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PRP88320.1 - 0.016 14.4 0.5 0.087 12.0 0.3 2.0 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.25 PRP88320.1 - 0.018 14.5 0.0 0.067 12.6 0.0 1.8 1 1 1 2 2 2 0 short chain dehydrogenase NmrA PF05368.13 PRP88320.1 - 0.023 14.3 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 PRP88320.1 - 0.062 12.3 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_2 PF00891.18 PRP88320.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain KR PF08659.10 PRP88320.1 - 0.083 12.8 0.2 0.26 11.2 0.1 1.7 1 1 1 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 PRP88320.1 - 0.091 11.9 0.1 0.3 10.2 0.2 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 PRP88320.1 - 0.12 12.9 0.1 0.37 11.4 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent vATP-synt_E PF01991.18 PRP88321.1 - 4.9e-63 212.1 12.9 6e-63 211.9 12.9 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SPACA7 PF15307.6 PRP88321.1 - 0.0077 16.5 3.3 0.053 13.8 0.0 2.2 2 0 0 2 2 2 1 Sperm acrosome-associated protein 7 Rio2_N PF09202.11 PRP88321.1 - 0.08 13.2 0.3 0.18 12.0 0.3 1.7 1 0 0 1 1 1 0 Rio2, N-terminal Phage_lysozyme2 PF18013.1 PRP88321.1 - 0.15 12.0 4.4 0.3 11.1 4.4 1.5 1 0 0 1 1 1 0 Phage tail lysozyme Imm27 PF15590.6 PRP88321.1 - 0.47 10.3 4.3 15 5.5 0.1 3.0 3 1 0 3 3 3 0 Immunity protein 27 ST7 PF04184.12 PRP88321.1 - 0.71 8.3 9.3 0.96 7.8 9.3 1.2 1 0 0 1 1 1 0 ST7 protein SecA_SW PF07516.13 PRP88321.1 - 4.4 7.3 15.3 4.2 7.4 1.0 2.2 1 1 1 2 2 2 0 SecA Wing and Scaffold domain Cas_DxTHG PF09455.10 PRP88321.1 - 4.5 6.8 12.7 5.5 6.5 12.7 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family BRAP2 PF07576.12 PRP88322.1 - 6.5e-28 96.9 0.0 1.5e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 PRP88322.1 - 6.3e-19 68.1 5.6 6.3e-19 68.1 5.6 2.2 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 PRP88322.1 - 4.2e-09 36.6 5.0 4.2e-09 36.6 5.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP88322.1 - 6.3e-08 32.3 4.1 6.3e-08 32.3 4.1 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP88322.1 - 3.2e-06 27.0 3.3 3.2e-06 27.0 3.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PRP88322.1 - 3.9e-06 26.8 4.8 4.4e-06 26.6 2.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PRP88322.1 - 7.6e-06 25.7 2.9 7.6e-06 25.7 2.9 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP88322.1 - 7.8e-05 22.3 3.8 7.8e-05 22.3 3.8 2.9 4 0 0 4 4 3 1 RING-like zinc finger zf-rbx1 PF12678.7 PRP88322.1 - 0.00041 20.6 6.7 0.00041 20.6 6.7 2.3 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PRP88322.1 - 0.00062 19.6 2.2 0.00062 19.6 2.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHF5 PF03660.14 PRP88322.1 - 0.029 14.6 5.7 0.039 14.2 4.7 1.6 1 1 0 1 1 1 0 PHF5-like protein zf-UBP_var PF17807.1 PRP88322.1 - 0.05 13.4 0.5 0.05 13.4 0.5 2.5 2 0 0 2 2 2 0 Variant UBP zinc finger zf-RING_4 PF14570.6 PRP88322.1 - 0.098 12.5 1.4 0.28 11.0 1.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PRP88322.1 - 0.23 11.6 9.0 0.045 13.8 4.4 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Exonuc_VII_L PF02601.15 PRP88322.1 - 2.4 7.7 5.8 4.4 6.8 5.7 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit ZapB PF06005.12 PRP88322.1 - 6 7.4 14.2 6.2 7.3 2.8 2.7 2 1 0 2 2 2 0 Cell division protein ZapB Hydrolase_4 PF12146.8 PRP88324.1 - 8.6e-19 67.7 0.1 1.4e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP88324.1 - 9.5e-19 68.0 0.3 5.2e-18 65.6 0.1 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP88324.1 - 1.9e-18 67.9 1.4 8e-18 65.9 0.2 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 PRP88324.1 - 1.2e-05 25.2 0.0 0.00022 21.0 0.0 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 PRP88324.1 - 5.7e-05 22.2 0.0 9e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 PRP88324.1 - 0.00016 21.3 0.0 0.006 16.1 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.13 PRP88324.1 - 0.00016 21.5 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 PRP88324.1 - 0.0006 19.4 0.0 0.0053 16.4 0.0 2.2 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Lipase_2 PF01674.18 PRP88324.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) BAAT_C PF08840.11 PRP88324.1 - 0.0016 18.4 0.8 0.29 11.0 0.0 2.9 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 PRP88324.1 - 0.0017 17.7 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 PRP88324.1 - 0.0029 17.5 0.0 0.0055 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.11 PRP88324.1 - 0.0037 16.3 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.16 PRP88324.1 - 0.0038 17.1 0.2 0.39 10.5 0.0 3.4 4 0 0 4 4 4 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 PRP88324.1 - 0.0046 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PAF-AH_p_II PF03403.13 PRP88324.1 - 0.0077 14.8 0.0 1.1 7.7 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 PRP88324.1 - 0.02 14.4 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 PRP88324.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 PRP88324.1 - 0.06 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_8 PF06259.12 PRP88324.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase TPR_1 PF00515.28 PRP88325.1 - 2e-24 84.3 2.9 3.2e-08 33.1 0.7 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 PRP88325.1 - 1e-16 59.6 8.7 5.5e-06 26.1 0.5 5.4 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 PRP88325.1 - 2.7e-11 43.0 0.5 0.00023 20.8 0.0 3.5 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 PRP88325.1 - 1.1e-09 38.8 4.0 0.032 14.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP88325.1 - 1.7e-08 34.0 3.4 5.3e-05 23.1 1.2 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 PRP88325.1 - 4.7e-08 33.1 4.4 0.0056 16.8 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PRP88325.1 - 1.8e-07 31.4 6.7 0.13 13.1 0.1 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP88325.1 - 0.0013 18.6 1.3 3.5 7.9 0.1 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP88325.1 - 0.0045 17.3 7.7 0.16 12.3 0.3 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP88325.1 - 0.01 16.4 1.1 0.029 15.0 0.6 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PRP88325.1 - 0.071 13.4 2.1 12 6.2 0.3 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PRP88325.1 - 0.097 13.2 0.9 67 4.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PRP88325.1 - 0.11 12.5 0.7 0.31 11.1 0.1 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 PRP88325.1 - 0.12 12.3 1.5 0.98 9.4 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 PRP88325.1 - 0.69 10.3 7.6 5.4 7.4 0.4 3.4 2 2 1 3 3 3 0 Bacterial transcriptional activator domain SAC3_GANP PF03399.16 PRP88326.1 - 3.8e-29 102.0 1.8 1.4e-27 96.8 1.8 2.1 1 1 0 1 1 1 1 SAC3/GANP family DUF2205 PF10224.9 PRP88327.1 - 9.9e-05 22.3 0.1 9.9e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Short coiled-coil protein FlaC_arch PF05377.11 PRP88327.1 - 0.11 13.0 1.5 0.16 12.3 1.5 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) AhpC-TSA PF00578.21 PRP88328.1 - 3.1e-32 111.1 0.0 6.2e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family SelK_SelG PF10961.8 PRP88328.1 - 8.1e-16 58.4 0.6 1.5e-15 57.5 0.6 1.4 1 0 0 1 1 1 1 Selenoprotein SelK_SelG Redoxin PF08534.10 PRP88328.1 - 3.2e-12 46.4 0.0 1.2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 PRP88328.1 - 1.8e-11 43.7 0.0 3.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Phosphodiest PF01663.22 PRP88329.1 - 3.8e-44 151.8 0.0 4.5e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ribosomal_S8 PF00410.19 PRP88329.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S8 B_lectin PF01453.24 PRP88331.1 - 4.8e-06 27.1 0.0 0.18 12.3 0.0 3.4 2 2 1 3 3 3 3 D-mannose binding lectin Beta_helix PF13229.6 PRP88331.1 - 0.00011 22.1 19.5 0.00011 22.1 19.5 3.4 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 PRP88331.1 - 0.012 14.9 8.1 0.82 8.9 0.8 2.6 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) IRK_C PF17655.1 PRP88332.1 - 6.8e-24 84.4 0.0 4.9e-20 71.8 0.0 2.4 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PRP88332.1 - 1.6e-09 37.8 5.1 5.4e-09 36.0 5.1 1.8 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 PRP88332.1 - 3.7e-06 26.8 4.5 6.4e-06 26.1 4.5 1.4 1 0 0 1 1 1 1 Ion channel DUF953 PF06110.11 PRP88333.1 - 1.6e-14 53.5 0.2 1.3e-13 50.6 0.2 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 PRP88333.1 - 0.0001 22.3 0.0 0.0049 16.8 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 PRP88333.1 - 0.012 15.8 0.0 0.055 13.7 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like MORN PF02493.20 PRP88336.1 - 2.5e-12 45.9 9.9 5.4e-06 26.0 0.3 3.6 3 0 0 3 3 3 2 MORN repeat zf-C3HC4_3 PF13920.6 PRP88336.1 - 5.5e-10 39.0 11.1 9e-10 38.3 11.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP88336.1 - 1e-06 28.5 11.5 1.9e-06 27.6 11.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 CDC24 PF06395.11 PRP88336.1 - 0.038 14.2 0.3 0.12 12.6 0.3 1.9 1 0 0 1 1 1 0 CDC24 Calponin NpwBP PF12622.7 PRP88337.1 - 3.2e-09 37.4 2.2 3.2e-09 37.4 2.2 9.1 4 2 1 5 5 5 1 mRNA biogenesis factor Wbp11 PF09429.10 PRP88337.1 - 0.00016 22.0 10.9 0.00016 22.0 10.9 1.9 2 0 0 2 2 2 1 WW domain binding protein 11 WPP PF13943.6 PRP88337.1 - 0.07 13.5 0.9 0.13 12.6 0.9 1.4 1 0 0 1 1 1 0 WPP domain Thioredoxin PF00085.20 PRP88338.1 - 6.5e-27 93.5 0.7 1.1e-26 92.8 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin UBX PF00789.20 PRP88338.1 - 1.1e-13 51.2 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 PRP88338.1 - 1.1e-07 31.6 0.1 2.5e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain OST3_OST6 PF04756.13 PRP88338.1 - 0.00019 20.9 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PRP88338.1 - 0.00035 21.0 1.5 0.00071 20.0 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PRP88338.1 - 0.00081 19.7 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PRP88338.1 - 0.0035 17.3 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family DUF572 PF04502.13 PRP88338.1 - 0.004 16.8 10.9 0.0055 16.4 10.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Thioredoxin_7 PF13899.6 PRP88338.1 - 0.011 15.9 2.1 0.011 15.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.6 PRP88338.1 - 0.03 14.1 0.0 0.03 14.1 0.0 2.3 3 0 0 3 3 3 0 Thioredoxin Glutaredoxin PF00462.24 PRP88338.1 - 0.11 12.7 0.7 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin Alpha_GJ PF03229.13 PRP88338.1 - 3.2 8.3 11.5 0.47 11.0 4.3 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J MPS2 PF17060.5 PRP88338.1 - 4.6 6.4 11.6 6.9 5.8 11.6 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 NDUFA12 PF05071.16 PRP88339.1 - 2.1e-08 34.9 2.2 4.8e-08 33.7 2.2 1.7 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ctr PF04145.15 PRP88340.1 - 0.2 12.2 5.9 0.38 11.4 1.3 3.0 2 1 0 2 2 2 0 Ctr copper transporter family SK_channel PF03530.14 PRP88340.1 - 0.54 10.3 6.6 1.3 9.0 2.3 2.8 2 0 0 2 2 2 0 Calcium-activated SK potassium channel Enkurin PF13864.6 PRP88341.1 - 2.2e-22 79.3 11.3 2.2e-22 79.3 11.3 1.7 2 0 0 2 2 2 1 Calmodulin-binding Bromodomain PF00439.25 PRP88341.1 - 0.014 15.5 0.1 0.034 14.2 0.1 1.6 1 0 0 1 1 1 0 Bromodomain MAS20 PF02064.15 PRP88341.1 - 0.66 10.1 10.1 0.078 13.1 4.9 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor MCM PF00493.23 PRP88343.1 - 1.1e-101 338.6 0.0 1.9e-101 337.9 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PRP88343.1 - 7.4e-37 126.0 0.1 7.4e-37 126.0 0.1 2.0 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 PRP88343.1 - 2.7e-27 95.0 0.3 6.1e-27 93.9 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PRP88343.1 - 8.3e-09 36.0 0.3 2.4e-08 34.5 0.3 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PRP88343.1 - 8.9e-08 31.8 0.0 7.2e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PRP88343.1 - 6.4e-07 29.5 0.0 3.3e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PRP88343.1 - 0.0011 18.8 0.0 0.0093 15.8 0.0 2.6 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 PRP88343.1 - 0.063 13.7 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PRP88343.1 - 0.12 12.1 0.0 19 4.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 PRP88343.1 - 0.12 12.8 0.1 1.5 9.2 0.0 2.5 1 1 1 2 2 2 0 AAA ATPase domain PCNA_C PF02747.15 PRP88344.1 - 4.1e-53 178.9 0.1 7e-52 175.0 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 PRP88344.1 - 1.6e-52 176.5 4.2 3.2e-52 175.6 4.2 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 PRP88344.1 - 0.0027 16.8 1.4 0.49 9.4 0.1 2.3 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 PRP88344.1 - 0.0043 16.5 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Rad9 FTP PF07504.13 PRP88344.1 - 0.24 11.3 1.2 2.2 8.2 0.0 2.6 3 0 0 3 3 3 0 Fungalysin/Thermolysin Propeptide Motif DIL PF01843.19 PRP88345.1 - 6.9e-17 61.6 0.1 3.5e-16 59.4 0.1 2.4 1 0 0 1 1 1 1 DIL domain NT-C2 PF10358.9 PRP88345.1 - 7.5e-16 58.2 1.2 7.5e-16 58.2 1.2 2.5 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins RskA PF10099.9 PRP88345.1 - 0.032 14.5 2.6 0.56 10.5 0.5 2.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RSN1_7TM PF02714.15 PRP88346.1 - 6.4e-57 192.9 27.8 6.4e-57 192.9 27.8 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 PRP88346.1 - 1.4e-21 77.5 0.1 2.1e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 PRP88346.1 - 1.5e-20 73.5 5.8 1.5e-20 73.5 5.8 3.6 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport Raptor_N PF14538.6 PRP88346.1 - 0.13 12.2 0.1 0.34 10.8 0.0 1.7 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain p450 PF00067.22 PRP88347.1 - 1e-86 291.5 0.0 1.3e-86 291.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TFIIA_gamma_N PF02268.16 PRP88347.1 - 0.16 12.0 0.1 0.44 10.6 0.1 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Endosulfine PF04667.17 PRP88348.1 - 6.7e-05 22.9 0.1 0.00026 21.1 0.1 2.0 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF2095 PF09868.9 PRP88348.1 - 0.015 15.3 0.5 0.044 13.7 0.3 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) Tim54 PF11711.8 PRP88348.1 - 0.076 11.8 7.8 0.15 10.8 7.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GAGA_bind PF06217.12 PRP88348.1 - 0.28 11.4 10.9 0.049 13.9 6.6 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family PIP49_N PF14875.6 PRP88348.1 - 0.33 10.8 2.2 0.98 9.3 1.1 2.4 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 DUF3464 PF11947.8 PRP88348.1 - 5.3 6.8 9.9 13 5.5 9.9 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Glyco_hydro_18 PF00704.28 PRP88349.1 - 2e-23 83.6 5.1 5.3e-23 82.2 5.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP88349.1 - 1.7e-06 28.4 10.2 1.7e-06 28.4 10.2 2.2 2 0 0 2 2 2 1 Chitin recognition protein Glucosaminidase PF01832.20 PRP88349.1 - 0.021 15.3 1.3 0.061 13.8 1.2 1.8 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase WD40 PF00400.32 PRP88350.1 - 4.2e-49 163.5 37.1 8.1e-06 26.5 0.2 9.6 9 0 0 9 9 9 9 WD domain, G-beta repeat Nup160 PF11715.8 PRP88350.1 - 2e-06 26.8 11.9 0.0075 15.0 0.2 5.9 2 2 4 6 6 6 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 PRP88350.1 - 0.0017 18.8 4.1 73 4.1 0.0 5.9 6 0 0 6 6 6 0 PQQ-like domain SHOCT PF09851.9 PRP88350.1 - 0.0053 16.5 0.3 0.0053 16.5 0.3 1.9 2 0 0 2 2 2 1 Short C-terminal domain AsnC_trans_reg PF01037.21 PRP88350.1 - 0.056 13.4 0.0 9.1 6.3 0.0 3.4 3 0 0 3 3 3 0 Lrp/AsnC ligand binding domain WD40_like PF17005.5 PRP88350.1 - 0.069 12.5 0.5 2 7.7 0.7 2.7 1 1 1 2 2 2 0 WD40-like domain UTP15_C PF09384.10 PRP88350.1 - 0.075 12.7 1.7 0.15 11.7 1.7 1.4 1 0 0 1 1 1 0 UTP15 C terminal ZYG-11_interact PF05884.12 PRP88350.1 - 0.5 9.7 2.7 0.83 9.0 0.7 2.1 2 0 0 2 2 2 0 Interactor of ZYG-11 TMF_TATA_bd PF12325.8 PRP88350.1 - 5.7 7.2 13.2 0.047 13.9 3.5 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PH PF00169.29 PRP88351.1 - 1.8e-30 105.5 4.8 8.1e-17 61.7 0.9 3.5 3 0 0 3 3 3 2 PH domain TMF_TATA_bd PF12325.8 PRP88351.1 - 7.9e-25 87.3 13.3 7.9e-25 87.3 13.3 8.5 3 2 4 7 7 7 1 TATA element modulatory factor 1 TATA binding PH_8 PF15409.6 PRP88351.1 - 1.7e-09 37.8 0.7 3.9e-05 23.8 0.2 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain TMF_DNA_bd PF12329.8 PRP88351.1 - 2.7e-09 36.9 16.3 2.7e-09 36.9 16.3 10.8 6 4 3 10 10 10 1 TATA element modulatory factor 1 DNA binding PH_9 PF15410.6 PRP88351.1 - 0.00015 22.1 4.2 0.036 14.4 0.1 4.3 3 1 0 3 3 3 1 Pleckstrin homology domain DUF5082 PF16888.5 PRP88351.1 - 0.0029 17.9 4.2 0.0029 17.9 4.2 7.7 5 3 2 7 7 7 2 Domain of unknown function (DUF5082) DHHC PF01529.20 PRP88352.1 - 3.1 7.9 11.8 6.6 6.8 11.8 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase CDP-OH_P_transf PF01066.21 PRP88353.1 - 5.3e-16 59.2 0.1 5.3e-16 59.2 0.1 3.6 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF2070 PF09843.9 PRP88353.1 - 3.3 5.9 13.1 1.3 7.2 10.7 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) KH_1 PF00013.29 PRP88354.1 - 2.9e-16 59.0 0.4 6.4e-16 57.9 0.4 1.6 1 0 0 1 1 1 1 KH domain DUF1771 PF08590.10 PRP88354.1 - 3.2e-11 43.4 8.4 3.2e-11 43.4 8.4 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 PRP88354.1 - 5.6e-08 33.0 0.0 5.6e-08 33.0 0.0 2.8 3 1 0 3 3 3 1 Smr domain KH_2 PF07650.17 PRP88354.1 - 1.9e-05 24.4 0.3 4.6e-05 23.2 0.3 1.8 1 0 0 1 1 1 1 KH domain SLS PF14611.6 PRP88354.1 - 0.00011 22.1 0.3 0.00015 21.7 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator SLC12 PF03522.15 PRP88354.1 - 0.04 12.9 1.7 0.049 12.7 1.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Alba PF01918.21 PRP88354.1 - 0.067 13.0 0.1 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 Alba Zn_Tnp_IS1595 PF12760.7 PRP88355.1 - 0.055 13.4 0.5 0.1 12.6 0.5 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 PRP88355.1 - 0.056 13.7 0.4 0.14 12.4 0.4 1.7 1 0 0 1 1 1 0 zinc-ribbon adh_short PF00106.25 PRP88356.1 - 8.8e-21 74.2 0.0 3.6e-16 59.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP88356.1 - 3.1e-12 46.6 0.0 3.4e-10 39.9 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP88356.1 - 0.00018 21.4 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Wound_ind PF08186.11 PRP88357.1 - 8.8e-08 32.5 0.1 1.2e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 Wound-inducible basic protein family PipA PF07108.11 PRP88358.1 - 0.056 13.0 1.0 7.1 6.1 0.1 2.3 2 0 0 2 2 2 0 PipA protein SAP18 PF06487.12 PRP88358.1 - 0.13 12.5 0.3 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) Co_AT_N PF12557.8 PRP88358.1 - 1.1 9.3 2.5 2.1 8.4 2.5 1.4 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal PAN_4 PF14295.6 PRP88359.1 - 4.3e-23 81.0 22.3 2.3e-09 37.0 1.2 4.1 4 0 0 4 4 4 3 PAN domain PAN_1 PF00024.26 PRP88359.1 - 0.0018 18.2 17.1 0.054 13.5 2.7 3.4 3 0 0 3 3 3 2 PAN domain PAN_2 PF08276.11 PRP88359.1 - 0.037 14.2 17.7 0.68 10.1 1.0 3.5 3 0 0 3 3 3 0 PAN-like domain RhoGEF PF00621.20 PRP88360.1 - 2.8e-45 154.8 0.0 1.2e-44 152.7 0.0 2.2 1 1 0 1 1 1 1 RhoGEF domain IQ_SEC7_PH PF16453.5 PRP88360.1 - 0.00016 21.6 0.2 0.00016 21.6 0.2 2.6 2 1 0 2 2 2 1 PH domain PH PF00169.29 PRP88360.1 - 0.00095 19.6 0.0 0.0021 18.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 PRP88360.1 - 0.011 15.6 7.5 0.023 14.5 1.0 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain GTP_EFTU PF00009.27 PRP88361.1 - 1.5e-50 171.5 0.1 3.3e-50 170.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 PRP88361.1 - 4.5e-47 158.6 0.4 8.2e-47 157.8 0.4 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 PRP88361.1 - 5.6e-21 74.4 0.2 3.1e-20 72.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PRP88361.1 - 5.7e-09 36.2 0.4 1.1e-08 35.3 0.4 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PRP88361.1 - 2.8e-06 27.3 0.0 6.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 PRP88361.1 - 0.00037 20.5 0.0 0.00086 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 PRP88361.1 - 0.0007 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 PRP88361.1 - 0.005 16.3 0.0 0.014 14.8 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PRP88361.1 - 0.036 13.7 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Ras family DAGK_acc PF00609.19 PRP88362.1 - 5.2e-48 163.4 0.0 7.3e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PRP88362.1 - 1.3e-24 86.2 0.0 2.3e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain STATa_Ig PF18214.1 PRP88362.1 - 0.0017 18.4 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 1 STATa Immunoglobulin-like domain Presenilin PF01080.17 PRP88366.1 - 0.59 8.8 21.4 0.91 8.2 21.4 1.3 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 PRP88366.1 - 0.69 8.8 16.7 1.2 8.1 16.7 1.4 1 0 0 1 1 1 0 Xrn1 helical domain SOBP PF15279.6 PRP88366.1 - 2.5 8.6 11.8 3.6 8.1 11.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 PRP88366.1 - 5.3 5.6 9.3 9.3 4.8 9.3 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNB PF00773.19 PRP88367.1 - 5.2e-99 331.7 0.0 7.5e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PRP88367.1 - 9.3e-19 67.2 0.0 3.2e-18 65.5 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 PRP88367.1 - 1.6e-09 37.7 0.1 3.5e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 PRP88367.1 - 5.6e-09 36.2 0.1 2e-08 34.4 0.1 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 PRP88367.1 - 3.9e-05 23.7 0.0 0.017 15.3 0.0 2.9 2 0 0 2 2 2 2 Cold shock domain AUDH_Cupin PF18637.1 PRP88367.1 - 0.14 12.1 0.5 0.32 11.0 0.5 1.5 1 0 0 1 1 1 0 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain FMO-like PF00743.19 PRP88368.1 - 1.5e-22 79.7 0.6 3.6e-21 75.2 0.6 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 PRP88368.1 - 3.5e-14 52.7 0.3 1.6e-11 44.0 0.1 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PRP88368.1 - 2.5e-12 46.8 0.0 3.3e-11 43.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PRP88368.1 - 1.3e-11 44.3 1.8 3.8e-10 39.5 1.8 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PRP88368.1 - 8.7e-06 25.2 0.0 8e-05 22.0 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP88368.1 - 8e-05 22.4 0.4 0.021 14.4 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 PRP88368.1 - 0.00025 20.4 0.3 0.00088 18.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 PRP88368.1 - 0.0013 19.2 0.8 0.25 11.9 0.2 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP88368.1 - 0.002 17.3 0.2 0.0042 16.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 PRP88368.1 - 0.021 14.8 0.0 0.35 10.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 PRP88368.1 - 0.11 11.2 0.1 0.11 11.2 0.1 2.7 4 0 0 4 4 4 0 HI0933-like protein Shikimate_DH PF01488.20 PRP88368.1 - 0.14 12.2 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 PRP88368.1 - 0.16 11.2 0.1 0.69 9.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain RhoGAP PF00620.27 PRP88369.1 - 2.2e-26 92.5 0.4 4.3e-26 91.6 0.4 1.4 1 0 0 1 1 1 1 RhoGAP domain AAA_2 PF07724.14 PRP88370.1 - 8.6e-56 188.7 0.0 3.1e-52 177.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PRP88370.1 - 6.2e-35 119.3 1.4 6.2e-35 119.3 1.4 3.4 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 PRP88370.1 - 1.5e-27 96.7 0.0 1.2e-14 54.8 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PRP88370.1 - 2.6e-21 75.5 1.6 2.6e-21 75.5 1.6 3.6 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PRP88370.1 - 1.6e-18 67.0 0.2 9e-12 45.2 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 PRP88370.1 - 7.7e-17 61.2 7.0 2.4e-08 34.0 0.3 3.9 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 PRP88370.1 - 1.3e-11 44.5 0.0 9.6e-07 28.7 0.0 3.0 2 1 1 3 3 3 2 Sigma-54 interaction domain AAA_22 PF13401.6 PRP88370.1 - 1.3e-10 41.7 2.0 0.00058 20.1 0.0 5.0 3 2 0 3 3 3 2 AAA domain AAA_16 PF13191.6 PRP88370.1 - 6.2e-10 39.7 17.2 3.5e-06 27.5 0.2 5.5 4 3 0 4 4 2 2 AAA ATPase domain IstB_IS21 PF01695.17 PRP88370.1 - 5.7e-09 36.0 0.0 0.0019 17.9 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 PRP88370.1 - 9.8e-09 35.3 0.1 0.0026 17.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 PRP88370.1 - 4.7e-07 29.5 0.0 0.0075 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 PRP88370.1 - 7.5e-07 28.7 0.3 0.0011 18.4 0.0 3.8 3 1 0 3 3 3 1 Bacterial TniB protein DUF87 PF01935.17 PRP88370.1 - 4.7e-06 26.9 2.6 0.087 12.9 0.0 3.8 3 0 0 3 3 3 1 Helicase HerA, central domain DUF815 PF05673.13 PRP88370.1 - 1.2e-05 24.6 0.6 0.07 12.3 0.0 3.6 4 1 0 4 4 4 2 Protein of unknown function (DUF815) AAA_28 PF13521.6 PRP88370.1 - 3.5e-05 24.1 3.2 0.58 10.4 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.6 PRP88370.1 - 4.2e-05 24.1 20.1 0.033 14.7 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 PRP88370.1 - 7e-05 23.4 2.2 0.15 12.6 0.0 3.7 4 0 0 4 4 2 2 AAA domain AAA_25 PF13481.6 PRP88370.1 - 8.5e-05 22.2 0.8 0.028 14.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 PRP88370.1 - 9.1e-05 22.4 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 PRP88370.1 - 0.0001 21.6 0.4 0.11 11.7 0.0 3.7 3 1 0 3 3 3 1 Zeta toxin Roc PF08477.13 PRP88370.1 - 0.00011 22.3 0.0 0.31 11.3 0.0 3.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 PRP88370.1 - 0.00015 20.9 0.2 0.0011 18.0 0.2 2.4 2 1 0 2 2 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 PRP88370.1 - 0.00016 21.1 0.2 1.1 8.6 0.0 3.7 3 1 1 4 4 4 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PRP88370.1 - 0.00016 22.0 0.0 0.65 10.4 0.0 3.1 3 0 0 3 3 2 1 RNA helicase RuvB_N PF05496.12 PRP88370.1 - 0.00022 21.0 5.2 0.17 11.7 0.0 4.7 4 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 PRP88370.1 - 0.00028 20.9 13.2 0.76 9.6 0.2 5.6 5 2 1 6 6 5 2 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 PRP88370.1 - 0.0006 19.8 0.9 2.9 7.8 0.0 4.0 4 0 0 4 4 4 1 RsgA GTPase DNA_pol3_delta2 PF13177.6 PRP88370.1 - 0.00063 19.6 0.0 0.014 15.2 0.0 2.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit TsaE PF02367.17 PRP88370.1 - 0.00072 19.6 0.0 2 8.5 0.0 3.0 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PRP88370.1 - 0.00073 19.7 0.0 1.1 9.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 PRP88370.1 - 0.0011 19.0 0.0 0.25 11.4 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PRP88370.1 - 0.0011 19.3 1.3 0.15 12.4 0.2 4.0 3 2 0 4 4 4 1 AAA domain ABC_tran PF00005.27 PRP88370.1 - 0.0012 19.3 3.1 0.26 11.8 0.0 3.8 3 1 0 3 3 3 1 ABC transporter TIP49 PF06068.13 PRP88370.1 - 0.0013 18.1 0.3 1.3 8.2 0.0 3.0 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_3 PF07726.11 PRP88370.1 - 0.0028 17.5 0.0 2.9 7.8 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PRP88370.1 - 0.0035 17.1 0.0 3.2 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 PRP88370.1 - 0.0057 16.1 0.0 1.7 8.1 0.0 2.8 2 0 0 2 2 2 1 PhoH-like protein AAA_29 PF13555.6 PRP88370.1 - 0.01 15.5 0.0 3.6 7.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain EMP24_GP25L PF01105.24 PRP88370.1 - 0.013 15.4 2.9 0.031 14.2 2.9 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AAA_30 PF13604.6 PRP88370.1 - 0.015 15.1 0.0 1.3 8.7 0.0 3.3 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 PRP88370.1 - 0.046 13.0 0.0 3.5 6.9 0.1 2.8 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 SRP54 PF00448.22 PRP88370.1 - 0.051 13.2 0.0 6 6.4 0.0 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain FTA4 PF13093.6 PRP88370.1 - 0.11 12.3 7.5 0.24 11.2 7.5 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Parvo_NS1 PF01057.17 PRP88370.1 - 0.12 11.5 0.0 6 5.9 0.0 2.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 CbiA PF01656.23 PRP88370.1 - 0.13 12.3 0.4 6.2 6.9 0.0 3.5 2 2 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE_N PF05157.15 PRP88370.1 - 0.22 11.8 2.3 2.3 8.5 0.0 3.5 4 0 0 4 4 3 0 Type II secretion system (T2SS), protein E, N-terminal domain AAA_11 PF13086.6 PRP88370.1 - 0.76 9.5 10.3 7.8 6.2 0.0 3.3 2 1 1 3 3 3 0 AAA domain Rx_N PF18052.1 PRP88370.1 - 3.5 8.0 10.3 70 3.8 5.8 3.7 2 1 1 3 3 3 0 Rx N-terminal domain Atg14 PF10186.9 PRP88370.1 - 5.2 6.1 12.5 8.6 5.3 12.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 PRP88371.1 - 1.6e-55 188.3 0.0 3.4e-55 187.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88371.1 - 1.7e-29 102.9 0.0 2.6e-23 82.6 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 PRP88371.1 - 4.7e-19 68.6 0.2 1.3e-18 67.2 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 PRP88371.1 - 4.4e-18 65.8 0.0 9.8e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP88371.1 - 7.9e-12 45.0 0.0 7.9e-12 45.0 0.0 2.3 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain MASE3 PF17159.4 PRP88371.1 - 5.3e-11 42.6 22.9 8.6e-11 41.9 22.9 1.3 1 0 0 1 1 1 1 Membrane-associated sensor domain Kinase-like PF14531.6 PRP88371.1 - 5.4e-07 29.2 0.0 0.00016 21.1 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 PRP88371.1 - 0.0013 17.5 0.9 0.0033 16.3 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 PRP88371.1 - 0.0031 17.5 0.0 0.06 13.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP88371.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PRP88371.1 - 0.027 13.5 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 PAS PF00989.25 PRP88371.1 - 0.12 12.4 0.0 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 PAS fold SNARE_assoc PF09335.11 PRP88372.1 - 1.6e-20 73.8 13.4 3.3e-20 72.7 5.1 2.8 2 1 1 3 3 3 2 SNARE associated Golgi protein OCIA PF07051.11 PRP88372.1 - 0.33 11.0 1.9 0.88 9.6 0.0 2.6 3 0 0 3 3 3 0 Ovarian carcinoma immunoreactive antigen (OCIA) DUF3139 PF11337.8 PRP88372.1 - 0.41 11.3 3.8 24 5.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) Abhydrolase_9_N PF15420.6 PRP88372.1 - 8.7 6.3 8.3 0.51 10.3 0.4 2.5 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF4455 PF14643.6 PRP88373.1 - 2.3e-23 82.6 27.5 2.3e-23 82.6 27.5 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF4455) Pox_polyA_pol_N PF12630.7 PRP88373.1 - 1.9 8.9 10.6 0.39 11.1 0.2 4.0 4 0 0 4 4 4 0 Poxvirus poly(A) polymerase N-terminal domain MOLO1 PF17175.4 PRP88373.1 - 2.6 8.2 9.3 0.15 12.2 1.5 3.1 3 0 0 3 3 3 0 Modulator of levamisole receptor-1 YlbE PF14003.6 PRP88373.1 - 5.6 7.5 9.8 0.42 11.1 0.5 4.1 4 0 0 4 4 4 0 YlbE-like protein BTB_2 PF02214.22 PRP88374.1 - 2.7e-18 66.1 0.0 4.3e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 PRP88374.1 - 5.9e-06 26.3 0.0 9.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CBFD_NFYB_HMF PF00808.23 PRP88375.1 - 1.4e-17 63.7 0.5 2.7e-17 62.8 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PRP88375.1 - 2.3e-08 34.5 0.2 3.1e-08 34.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 PRP88375.1 - 2.8e-05 24.2 0.4 5.3e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 PRP88375.1 - 0.014 15.5 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold FYVE_2 PF02318.16 PRP88375.1 - 0.07 13.3 1.9 0.16 12.2 1.9 1.6 1 1 0 1 1 1 0 FYVE-type zinc finger NTP_transf_9 PF04248.12 PRP88376.1 - 7.7e-30 102.6 0.7 8.7e-30 102.5 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Antimicrobial15 PF08110.12 PRP88376.1 - 0.011 15.9 1.0 0.028 14.6 1.0 1.6 1 0 0 1 1 1 0 Ocellatin family Peptidase_M48_N PF16491.5 PRP88377.1 - 7.2e-65 218.3 7.7 7.2e-65 218.3 7.7 2.1 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 PRP88377.1 - 5.1e-37 127.6 0.0 1.1e-36 126.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 PRP88377.1 - 5.5e-05 22.5 4.7 5.7e-05 22.4 2.7 1.8 1 1 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.6 PRP88377.1 - 0.059 13.1 1.2 0.25 11.1 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF2268 PF10026.9 PRP88377.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF3593 PF12159.8 PRP88377.1 - 1.9 8.6 8.8 7 6.8 2.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) WD40_3 PF15911.5 PRP88379.1 - 6.1e-18 64.6 0.0 1.5e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat Clathrin PF00637.20 PRP88379.1 - 3.3e-10 40.0 5.9 0.011 15.6 0.0 4.5 3 1 1 4 4 4 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 PRP88379.1 - 7.4e-10 38.4 12.5 0.00035 19.8 0.2 5.4 4 1 0 5 5 5 4 Coatomer WD associated region ANAPC4_WD40 PF12894.7 PRP88379.1 - 4.3e-09 36.5 0.0 0.055 13.8 0.0 5.1 4 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain RPN1_RPN2_N PF17781.1 PRP88379.1 - 0.0012 18.3 2.4 0.77 9.1 0.1 3.1 1 1 2 3 3 3 2 RPN1/RPN2 N-terminal domain WD40 PF00400.32 PRP88379.1 - 0.0033 18.2 5.3 13 6.9 0.0 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat IKI3 PF04762.12 PRP88379.1 - 0.0037 15.3 0.0 0.012 13.7 0.0 1.8 1 0 0 1 1 1 1 IKI3 family WD40_like PF17005.5 PRP88379.1 - 0.0041 16.5 0.0 0.31 10.3 0.0 2.8 2 1 0 2 2 2 1 WD40-like domain SGL PF08450.12 PRP88379.1 - 0.016 14.8 0.0 2 7.9 0.0 3.0 2 1 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PALB2_WD40 PF16756.5 PRP88379.1 - 0.036 13.0 0.1 0.16 10.9 0.0 2.1 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Mad3_BUB1_I PF08311.12 PRP88379.1 - 0.12 12.4 3.5 1.1 9.3 0.1 3.2 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 DZR PF12773.7 PRP88379.1 - 0.63 10.1 9.8 8.4 6.5 9.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon UBZ_FAAP20 PF15750.5 PRP88379.1 - 0.67 9.9 6.1 0.11 12.4 1.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger ANAPC3 PF12895.7 PRP88379.1 - 0.91 9.8 4.7 1.3 9.3 0.0 3.7 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PGAP1 PF07819.13 PRP88380.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DUF829 PF05705.14 PRP88380.1 - 0.0032 17.4 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF676 PF05057.14 PRP88380.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 PRP88380.1 - 0.17 12.5 0.0 0.59 10.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family PH PF00169.29 PRP88382.1 - 9.1e-10 39.0 0.2 3.9e-09 37.0 0.2 2.2 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 PRP88382.1 - 1.2e-08 35.1 0.1 4.1e-08 33.4 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DUF948 PF06103.11 PRP88382.1 - 1.2 9.4 5.0 8.8 6.7 0.7 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FG-GAP_2 PF14312.6 PRP88383.1 - 0.00092 19.4 19.7 0.0094 16.2 1.3 5.0 5 0 0 5 5 5 2 FG-GAP repeat Conotoxin_I2 PF17557.2 PRP88383.1 - 0.65 10.2 12.4 1.9 8.7 12.4 1.9 1 0 0 1 1 1 0 I2-superfamily conotoxins Toxin_12 PF07740.12 PRP88383.1 - 1.1 10.0 10.3 3.3 8.5 10.3 1.8 1 0 0 1 1 1 0 Ion channel inhibitory toxin DUF3439 PF11921.8 PRP88383.1 - 1.5 8.8 15.2 0.095 12.7 7.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-C3Hc3H PF13891.6 PRP88384.1 - 9.8e-05 22.6 8.8 0.00037 20.8 8.8 2.1 1 1 0 1 1 1 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.8 PRP88384.1 - 4.5 7.1 9.5 4.7 7.1 0.8 2.6 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein Pkinase PF00069.25 PRP88385.1 - 2.2e-45 155.1 0.0 3.8e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RhoGAP PF00620.27 PRP88385.1 - 2.6e-39 134.5 0.0 5.2e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Pkinase_Tyr PF07714.17 PRP88385.1 - 4.2e-34 118.0 0.0 1e-33 116.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP88385.1 - 0.00098 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Presenilin PF01080.17 PRP88385.1 - 1.1 8.0 3.1 2 7.1 3.1 1.3 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 PRP88385.1 - 6.6 5.4 7.7 12 4.5 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) WD40 PF00400.32 PRP88387.1 - 6.9e-14 52.0 25.3 6.5e-06 26.8 0.4 7.5 7 1 0 7 7 6 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 PRP88387.1 - 2.4e-09 36.7 13.3 2.4e-09 36.7 13.3 2.2 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type TIG PF01833.24 PRP88387.1 - 1e-06 28.7 12.2 0.00024 21.1 0.8 3.9 3 1 1 4 4 3 2 IPT/TIG domain Insulin_TMD PF17870.1 PRP88387.1 - 0.024 14.7 3.4 0.06 13.4 3.4 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF5385 PF17359.2 PRP88387.1 - 0.13 11.8 0.3 0.19 11.2 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Chlam_PMP PF02415.17 PRP88387.1 - 0.15 12.6 0.1 0.15 12.6 0.1 8.2 9 0 0 9 9 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF3377 PF11857.8 PRP88387.1 - 0.18 11.7 0.7 0.39 10.7 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) PTP_tm PF18861.1 PRP88387.1 - 0.22 11.5 1.5 0.96 9.4 0.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J zinc_ribbon_16 PF17034.5 PRP88387.1 - 0.32 11.2 14.3 2.5 8.3 14.3 2.4 1 1 0 1 1 1 0 Zinc-ribbon like family PRIMA1 PF16101.5 PRP88387.1 - 0.66 10.0 3.8 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Amnionless PF14828.6 PRP88387.1 - 1.3 7.8 9.2 0.94 8.2 0.1 2.2 2 0 0 2 2 2 0 Amnionless Syndecan PF01034.20 PRP88387.1 - 1.6 8.7 3.9 4.2 7.3 3.9 1.6 1 0 0 1 1 1 0 Syndecan domain DZR PF12773.7 PRP88387.1 - 2.2 8.4 11.3 0.65 10.1 6.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon AbiEii PF08843.11 PRP88388.1 - 7.8e-08 32.5 0.0 2.4e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system OST-HTH PF12872.7 PRP88388.1 - 7.7e-05 22.4 0.0 0.00024 20.9 0.0 1.9 1 0 0 1 1 1 1 OST-HTH/LOTUS domain CASP_C PF08172.12 PRP88388.1 - 0.084 12.2 6.9 0.14 11.4 6.9 1.3 1 0 0 1 1 1 0 CASP C terminal DUF2353 PF09789.9 PRP88388.1 - 0.21 10.9 8.1 0.39 10.0 8.1 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) PHC2_SAM_assoc PF16616.5 PRP88388.1 - 0.34 11.7 8.7 0.063 14.1 3.8 2.0 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 TFIIA PF03153.13 PRP88388.1 - 0.57 10.1 10.6 0.81 9.6 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cnn_1N PF07989.11 PRP88388.1 - 2 8.7 6.4 0.15 12.2 0.9 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF4407 PF14362.6 PRP88388.1 - 2.1 7.6 6.7 3.2 7.0 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 PRP88388.1 - 2.2 7.3 10.4 3.7 6.5 10.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIVA PF05103.13 PRP88388.1 - 3 7.9 10.2 0.2 11.7 1.6 2.8 2 1 1 3 3 3 0 DivIVA protein FAM76 PF16046.5 PRP88388.1 - 5.3 6.3 10.0 8.2 5.7 10.0 1.2 1 0 0 1 1 1 0 FAM76 protein TMF_DNA_bd PF12329.8 PRP88388.1 - 6 6.9 10.6 0.16 11.9 3.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.32 PRP88389.1 - 5.8e-40 134.6 21.5 0.00031 21.5 0.0 12.1 13 0 0 13 13 13 9 WD domain, G-beta repeat Ank_2 PF12796.7 PRP88389.1 - 1.4e-34 118.5 0.1 1e-12 48.4 0.0 4.3 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP88389.1 - 3.4e-18 65.4 0.0 0.019 15.3 0.0 6.9 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP88389.1 - 2.7e-17 62.9 0.2 0.013 16.1 0.0 6.3 3 3 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88389.1 - 1.5e-16 58.8 0.0 0.49 11.1 0.0 8.4 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 PRP88389.1 - 1.7e-14 53.5 0.0 0.029 14.8 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat PQQ_3 PF13570.6 PRP88389.1 - 4.7e-07 30.1 5.4 11 6.7 0.0 9.8 11 1 1 12 12 12 1 PQQ-like domain ANAPC4_WD40 PF12894.7 PRP88389.1 - 6.4e-06 26.4 0.9 0.11 12.9 0.0 6.1 6 2 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PRP88389.1 - 0.0011 17.7 1.3 1.3 7.6 0.0 4.4 4 1 0 4 4 4 1 Nucleoporin Nup120/160 G0-G1_switch_2 PF15103.6 PRP88392.1 - 0.0035 17.8 4.9 5.9 7.4 0.1 3.6 3 1 0 3 3 3 3 G0/G1 switch protein 2 DUF3921 PF13060.6 PRP88392.1 - 0.16 12.0 18.7 2.2 8.4 0.0 6.3 8 0 0 8 8 8 0 Protein of unknown function (DUF3921) T7SS_ESX_EspC PF10824.8 PRP88392.1 - 4.1 7.9 18.0 1.8 9.1 0.4 5.5 2 2 6 8 8 8 0 Excreted virulence factor EspC, type VII ESX diderm Sacchrp_dh_NADP PF03435.18 PRP88393.1 - 8.2e-18 64.9 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 PRP88393.1 - 0.0023 17.9 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Condensin2nSMC PF12422.8 PRP88394.1 - 0.0061 16.7 0.3 0.023 14.9 0.3 2.1 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit NuiA PF07924.11 PRP88394.1 - 0.051 14.0 1.0 0.16 12.4 1.0 1.8 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Bromo_TP_like PF17027.5 PRP88394.1 - 5.4 7.2 7.7 11 6.2 2.9 3.2 3 1 0 3 3 3 0 Histone-fold protein N6_N4_Mtase PF01555.18 PRP88396.1 - 0.0031 17.2 0.4 0.0065 16.2 0.0 1.8 2 0 0 2 2 2 1 DNA methylase Astro_capsid_p PF12226.8 PRP88396.1 - 0.32 10.1 4.8 0.49 9.5 4.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Rap_GAP PF02145.15 PRP88397.1 - 5.8e-60 202.0 0.0 3.4e-59 199.5 0.0 2.0 2 0 0 2 2 2 1 Rap/ran-GAP DUF2905 PF11146.8 PRP88397.1 - 6.9e-07 29.3 2.2 2.8e-06 27.4 2.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2905) CagX PF03524.15 PRP88397.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein Peptidase_C50 PF03568.17 PRP88398.1 - 0.0083 15.3 0.2 0.0091 15.2 0.2 1.0 1 0 0 1 1 1 1 Peptidase family C50 Cys_rich_VLP PF14194.6 PRP88401.1 - 0.14 12.3 0.9 0.2 11.8 0.9 1.2 1 0 0 1 1 1 0 Cysteine-rich VLP Oxidored_molyb PF00174.19 PRP88402.1 - 4e-55 186.1 0.0 8e-55 185.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PRP88402.1 - 4.5e-25 88.3 0.3 9e-25 87.3 0.3 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 PRP88402.1 - 0.034 14.9 0.0 0.095 13.5 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig domain MMR_HSR1_Xtn PF16897.5 PRP88403.1 - 2.8e-42 143.0 0.0 5e-42 142.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 PRP88403.1 - 2.6e-21 75.9 0.0 5.6e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 PRP88403.1 - 1.7e-19 69.6 0.0 3.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 PRP88403.1 - 3e-12 46.4 0.0 5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 PRP88403.1 - 0.0082 15.6 0.1 0.026 14.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 PRP88403.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 PRP88403.1 - 0.018 15.1 0.1 5.2 7.1 0.0 2.4 1 1 1 2 2 2 0 Dynamin family AAA_28 PF13521.6 PRP88403.1 - 0.046 14.0 0.2 0.09 13.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 PRP88403.1 - 0.062 13.5 0.0 0.54 10.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_16 PF00722.21 PRP88404.1 - 2.5e-25 89.0 0.4 3.3e-25 88.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 PRP88404.1 - 0.00043 18.8 11.4 0.0014 17.1 1.1 3.1 2 1 1 3 3 3 3 Beta-glucan synthesis-associated protein (SKN1) HLH PF00010.26 PRP88405.1 - 5e-05 23.2 1.2 5e-05 23.2 1.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain CASP_C PF08172.12 PRP88405.1 - 0.021 14.1 0.4 0.029 13.7 0.4 1.2 1 0 0 1 1 1 0 CASP C terminal GTP-bdg_M PF16360.5 PRP88405.1 - 0.07 13.7 6.7 0.14 12.7 1.1 2.7 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region SKA2 PF16740.5 PRP88405.1 - 0.093 12.5 1.7 0.19 11.5 1.6 1.5 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Lipoprotein_7 PF01540.16 PRP88405.1 - 0.13 11.5 2.2 0.23 10.7 2.2 1.3 1 1 0 1 1 1 0 Adhesin lipoprotein MukF_M PF17192.4 PRP88405.1 - 0.14 11.9 0.5 0.33 10.7 0.3 1.7 1 1 1 2 2 2 0 MukF middle domain PH_6 PF15406.6 PRP88407.1 - 0.074 13.3 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Rubis-subs-bind PF09273.11 PRP88407.1 - 0.15 12.7 0.0 3.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding MMR_HSR1 PF01926.23 PRP88408.1 - 5.7e-22 78.0 0.0 1.1e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP88408.1 - 1.2e-08 35.0 0.0 2.8e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 PRP88408.1 - 6.7e-08 32.2 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 PRP88408.1 - 7.8e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 PRP88408.1 - 0.00017 21.7 0.2 0.00093 19.3 0.2 2.0 1 1 0 1 1 1 1 Dynamin family AAA_29 PF13555.6 PRP88408.1 - 0.0039 16.9 0.0 0.069 12.9 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 PRP88408.1 - 0.0094 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Septin PF00735.18 PRP88408.1 - 0.025 13.9 0.2 0.15 11.3 0.1 2.0 1 1 0 1 1 1 0 Septin PduV-EutP PF10662.9 PRP88408.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 PRP88408.1 - 0.09 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 PRP88408.1 - 0.11 11.8 0.2 0.34 10.2 0.1 1.8 1 1 1 2 2 2 0 AIG1 family Roc PF08477.13 PRP88408.1 - 0.14 12.4 0.2 0.3 11.3 0.2 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_47 PF01532.20 PRP88409.1 - 2.7e-128 428.7 4.4 3.2e-128 428.5 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AMPK1_CBM PF16561.5 PRP88411.1 - 2.1e-07 31.0 0.3 4e-07 30.2 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pur_ac_phosph_N PF16656.5 PRP88411.1 - 2 9.0 5.9 21 5.8 5.9 2.8 1 1 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Strabismus PF06638.11 PRP88411.1 - 8.6 4.9 8.7 15 4.1 8.7 1.3 1 0 0 1 1 1 0 Strabismus protein ABC_membrane PF00664.23 PRP88412.1 - 2.4e-73 247.2 27.1 7.5e-42 143.9 6.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PRP88412.1 - 2.5e-50 170.5 0.5 8.9e-28 97.5 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 PRP88412.1 - 1.2e-09 37.9 3.9 0.0044 16.5 0.1 4.3 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PRP88412.1 - 1.2e-05 25.3 0.9 0.045 13.6 0.1 3.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PRP88412.1 - 2.2e-05 24.1 0.1 0.31 10.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PRP88412.1 - 2.2e-05 24.5 0.8 0.072 13.2 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PRP88412.1 - 3.8e-05 24.1 0.0 0.19 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 PRP88412.1 - 0.00012 21.0 3.7 0.0024 16.8 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class MTABC_N PF16185.5 PRP88412.1 - 0.00013 21.6 4.0 0.00013 21.6 4.0 2.9 4 1 0 4 4 3 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_15 PF13175.6 PRP88412.1 - 0.00017 21.5 0.0 0.028 14.2 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PRP88412.1 - 0.00079 19.4 0.0 0.47 10.3 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 PRP88412.1 - 0.0012 19.4 2.2 0.74 10.3 2.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP88412.1 - 0.0028 17.4 2.5 0.86 9.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 PRP88412.1 - 0.02 14.5 0.2 0.38 10.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 PRP88412.1 - 0.029 14.1 0.8 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PRP88412.1 - 0.05 12.7 0.0 4.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 PRP88412.1 - 0.093 13.0 2.2 9.7 6.5 0.3 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 PRP88412.1 - 0.096 12.0 2.8 4.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.19 PRP88412.1 - 0.13 11.8 2.3 0.63 9.6 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 PRP88412.1 - 0.14 12.2 0.1 0.14 12.2 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Dynamin_N PF00350.23 PRP88412.1 - 4.1 7.4 11.6 1.6 8.8 0.1 3.2 4 0 0 4 4 4 0 Dynamin family Roc PF08477.13 PRP88412.1 - 6.3 7.0 6.0 28 4.9 0.1 3.4 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase Esterase_phd PF10503.9 PRP88413.1 - 1.2e-05 24.9 1.6 5.1e-05 22.9 0.1 2.9 2 1 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 PRP88413.1 - 0.0076 15.7 0.1 0.036 13.5 0.1 1.9 1 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 PRP88413.1 - 0.029 14.2 0.1 0.071 12.9 0.1 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 PRP88413.1 - 0.058 12.1 0.0 0.16 10.6 0.0 1.7 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) FTHFS PF01268.19 PRP88414.1 - 8e-262 869.4 0.1 9.2e-262 869.2 0.1 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Amidase PF01425.21 PRP88416.1 - 5.2e-102 342.1 0.0 6.3e-102 341.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Amastin PF07344.11 PRP88418.1 - 0.13 12.1 0.6 0.22 11.4 0.6 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF1996 PF09362.10 PRP88419.1 - 6.4e-71 239.1 3.0 8.8e-71 238.6 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RicinB_lectin_2 PF14200.6 PRP88419.1 - 0.15 12.8 0.0 0.36 11.6 0.0 1.6 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like Phage_holin_5_2 PF16079.5 PRP88421.1 - 0.054 13.8 0.8 0.054 13.8 0.8 2.1 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V CoA_binding_3 PF13727.6 PRP88421.1 - 0.16 12.0 3.1 0.23 11.4 0.7 1.9 1 1 0 2 2 2 0 CoA-binding domain RasGAP PF00616.19 PRP88422.1 - 2.6e-23 82.8 4.4 2.9e-17 63.1 0.2 2.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 PRP88422.1 - 3.2e-10 40.2 0.0 5.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain RICTOR_M PF14666.6 PRP88422.1 - 0.0011 18.7 0.4 0.13 12.1 0.0 2.7 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain UPF0147 PF03685.13 PRP88422.1 - 0.1 12.6 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) MMS19_N PF14500.6 PRP88423.1 - 9.2e-90 300.8 8.4 9.5e-86 287.6 0.5 4.7 3 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 PRP88423.1 - 9.7e-44 150.1 2.0 9.7e-44 150.1 2.0 3.6 3 1 0 4 4 4 2 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 PRP88423.1 - 2.8e-05 24.4 2.0 0.014 15.8 0.2 4.0 3 0 0 3 3 3 1 HEAT repeats SAS4 PF15460.6 PRP88423.1 - 0.034 14.2 0.3 0.14 12.2 0.3 2.1 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 DUF4704 PF15787.5 PRP88423.1 - 0.062 12.5 7.3 0.4 9.9 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4704) HEAT_EZ PF13513.6 PRP88423.1 - 0.14 12.7 3.9 13 6.4 0.2 5.8 6 1 1 7 7 7 0 HEAT-like repeat V-ATPase_H_C PF11698.8 PRP88423.1 - 0.83 9.8 4.2 1.1 9.4 0.4 3.2 4 0 0 4 4 4 0 V-ATPase subunit H Cnd1 PF12717.7 PRP88423.1 - 4.2 7.4 11.1 1.3 9.0 0.5 4.6 6 0 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 MFS_1_like PF12832.7 PRP88424.1 - 2.5e-66 224.1 25.6 3.9e-66 223.5 25.6 1.3 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 PRP88424.1 - 1.7e-20 73.3 42.4 3.6e-12 45.9 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PRP88424.1 - 5.5e-16 58.6 21.1 7.6e-16 58.1 21.1 1.1 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 PRP88424.1 - 0.0018 17.1 26.8 0.057 12.2 8.5 2.1 2 0 0 2 2 2 2 LacY proton/sugar symporter LRR_6 PF13516.6 PRP88425.1 - 1.5e-12 46.5 10.1 2.6e-05 23.9 0.1 5.0 5 0 0 5 5 5 3 Leucine Rich repeat Tropomyosin_1 PF12718.7 PRP88425.1 - 0.0064 16.7 9.0 0.013 15.7 9.0 1.4 1 0 0 1 1 1 1 Tropomyosin like SNCAIP_SNCA_bd PF16700.5 PRP88425.1 - 0.016 14.9 3.1 0.016 14.9 3.1 2.0 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain HeLo PF14479.6 PRP88425.1 - 0.029 14.2 1.8 0.063 13.1 1.8 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF4795 PF16043.5 PRP88425.1 - 0.037 13.6 6.0 0.06 12.9 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF489 PF04356.12 PRP88425.1 - 0.049 13.6 3.7 0.16 12.0 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF489) IFT57 PF10498.9 PRP88425.1 - 0.22 10.5 11.8 0.26 10.2 10.6 1.5 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 CC2-LZ PF16516.5 PRP88425.1 - 0.41 11.1 11.2 0.55 10.6 10.4 1.7 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF16 PF01519.16 PRP88425.1 - 1.2 9.6 13.7 3.8 8.0 6.1 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 APG6_N PF17675.1 PRP88425.1 - 2.2 8.8 12.5 23 5.5 12.5 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3552 PF12072.8 PRP88425.1 - 2.9 7.2 13.5 8 5.8 13.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) LMBR1 PF04791.16 PRP88425.1 - 3.2 6.6 4.5 4.8 6.0 4.5 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 PRP88425.1 - 3.6 8.3 8.1 28 5.4 8.1 2.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF1664 PF07889.12 PRP88425.1 - 7.8 6.6 10.5 5.2 7.1 4.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 PRP88425.1 - 8.3 7.1 12.1 48 4.7 2.2 3.0 1 1 1 2 2 2 0 SlyX Acyltransferase PF01553.21 PRP88426.1 - 4.9e-20 71.5 0.0 1.1e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Piwi PF02171.17 PRP88427.1 - 1.7e-71 241.0 0.3 3.1e-71 240.1 0.3 1.5 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 PRP88427.1 - 1.3e-06 28.3 0.1 2.4e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 PRP88427.1 - 1.1e-05 26.1 0.4 8.5e-05 23.2 0.1 2.7 3 0 0 3 3 3 1 N-terminal domain of argonaute ArgoL1 PF08699.10 PRP88427.1 - 2.3e-05 24.0 0.0 7.2e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain Ank_2 PF12796.7 PRP88434.1 - 7.2e-35 119.4 0.6 2.9e-14 53.4 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP88434.1 - 3.8e-26 91.1 0.1 5.2e-10 39.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP88434.1 - 1.4e-24 85.4 0.5 2.1e-06 27.9 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 PRP88434.1 - 2.8e-21 73.3 0.1 0.00041 20.6 0.0 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 PRP88434.1 - 1.5e-20 73.0 1.5 5.7e-09 36.1 0.1 4.4 1 1 4 5 5 5 4 Ankyrin repeats (many copies) TIG PF01833.24 PRP88434.1 - 9e-10 38.5 0.6 5.1e-09 36.1 0.1 2.6 3 0 0 3 3 3 1 IPT/TIG domain S1-P1_nuclease PF02265.16 PRP88435.1 - 2.9e-54 184.5 0.3 1.1e-53 182.7 0.0 1.9 2 0 0 2 2 2 1 S1/P1 Nuclease Carb_bind PF10645.9 PRP88435.1 - 0.0015 18.7 13.8 0.0015 18.7 13.8 2.9 2 1 1 3 3 3 2 Carbohydrate binding RIFIN PF02009.16 PRP88435.1 - 1.1 9.0 4.4 1.8 8.4 4.4 1.2 1 0 0 1 1 1 0 Rifin Mucin PF01456.17 PRP88435.1 - 3.6 7.6 36.0 0.87 9.6 31.5 2.3 2 1 0 2 2 2 0 Mucin-like glycoprotein PIN_6 PF17146.4 PRP88436.1 - 1.2e-25 89.8 0.0 2.7e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 PRP88436.1 - 1.4e-24 86.0 1.3 2.8e-24 85.1 1.3 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF4337 PF14235.6 PRP88436.1 - 0.0041 17.3 3.5 0.0081 16.3 3.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) Presenilin PF01080.17 PRP88436.1 - 0.04 12.7 10.6 0.054 12.3 10.6 1.2 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 PRP88436.1 - 0.074 12.5 21.9 0.14 11.6 21.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4045 PF13254.6 PRP88436.1 - 0.11 12.1 11.8 0.15 11.7 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RecR PF02132.15 PRP88436.1 - 0.16 11.6 1.7 0.32 10.6 1.7 1.5 1 0 0 1 1 1 0 RecR protein CDC27 PF09507.10 PRP88436.1 - 0.26 10.6 25.3 0.4 10.0 25.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 PRP88436.1 - 0.32 10.7 26.7 0.66 9.7 26.7 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF913 PF06025.12 PRP88436.1 - 0.32 9.9 7.2 0.48 9.3 7.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 PRP88436.1 - 0.36 10.0 8.9 0.59 9.3 8.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 PRP88436.1 - 0.64 9.3 26.7 1.1 8.6 26.7 1.3 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 PRP88436.1 - 2.8 7.7 21.4 5.3 6.8 21.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_3_Rpc31 PF11705.8 PRP88436.1 - 3.2 8.0 34.2 6.9 6.9 34.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Neur_chan_memb PF02932.16 PRP88436.1 - 7.1 6.6 6.3 11 6.0 6.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAP PF02037.27 PRP88437.1 - 1.7e-14 53.1 1.8 4.9e-06 26.2 0.1 2.5 2 0 0 2 2 2 2 SAP domain RTT107_BRCT_5 PF16770.5 PRP88437.1 - 2.1e-10 40.3 0.0 1e-09 38.2 0.0 2.3 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 PRP88437.1 - 4e-07 30.4 0.0 0.00031 21.1 0.0 3.0 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PRP88437.1 - 6.6e-07 29.6 0.0 0.0025 18.2 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Yop-YscD_cpl PF16697.5 PRP88437.1 - 0.00011 22.4 0.0 0.00031 21.0 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain LIG3_BRCT PF16759.5 PRP88437.1 - 0.016 15.4 0.2 0.29 11.5 0.0 3.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain ArfGap PF01412.18 PRP88438.1 - 6.3e-35 119.8 5.3 6.3e-35 119.8 5.3 3.3 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 PRP88438.1 - 2.3e-34 119.2 14.0 4.5e-34 118.2 14.0 1.5 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 PRP88438.1 - 4.3e-13 49.7 1.1 2.3e-06 28.1 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) PH PF00169.29 PRP88438.1 - 2.4e-11 44.1 4.6 2.9e-10 40.6 0.7 3.4 2 2 0 2 2 2 1 PH domain Ank_4 PF13637.6 PRP88438.1 - 1.9e-10 41.1 0.0 0.0052 17.3 0.0 3.9 4 0 0 4 4 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP88438.1 - 4.9e-10 39.5 0.0 3.4e-09 36.8 0.0 2.5 2 1 1 3 3 2 2 Ankyrin repeats (many copies) BAR PF03114.18 PRP88438.1 - 2.1e-07 30.9 9.6 2.1e-07 30.9 9.6 2.2 2 0 0 2 2 2 1 BAR domain Ank PF00023.30 PRP88438.1 - 2.5e-05 24.5 0.0 0.51 10.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PRP88438.1 - 0.00047 20.4 0.0 0.96 10.2 0.0 3.1 3 0 0 3 3 2 2 Ankyrin repeat PH_11 PF15413.6 PRP88438.1 - 0.0015 18.9 9.3 0.0067 16.8 0.4 3.6 2 1 1 3 3 3 2 Pleckstrin homology domain DUF3552 PF12072.8 PRP88438.1 - 0.0075 15.7 2.7 0.0075 15.7 2.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) PH_8 PF15409.6 PRP88438.1 - 0.088 13.1 0.5 0.38 11.1 0.5 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 PRP88438.1 - 0.4 11.1 6.9 0.94 9.9 0.1 3.5 2 1 1 3 3 3 0 Pleckstrin homology domain Ras PF00071.22 PRP88439.1 - 4.9e-56 188.8 0.0 5.6e-56 188.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88439.1 - 4.1e-19 69.0 0.0 6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP88439.1 - 5e-09 35.8 0.0 6.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP88439.1 - 2.4e-05 24.0 0.1 8.1e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP88439.1 - 0.0019 18.1 0.0 0.56 10.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PRP88439.1 - 0.0079 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 PRP88439.1 - 0.016 15.0 2.8 0.021 14.6 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein SWIM PF04434.17 PRP88440.1 - 0.00015 21.4 0.2 0.00036 20.1 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger RNA_polI_A34 PF08208.11 PRP88440.1 - 0.0014 18.8 9.8 0.0014 18.8 9.8 2.8 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Importin_rep_4 PF18808.1 PRP88441.1 - 7.6e-20 71.0 9.3 8.1e-19 67.7 0.3 4.3 3 1 1 4 4 4 1 Importin repeat HEAT_EZ PF13513.6 PRP88441.1 - 3.7e-16 59.2 5.8 3.5e-08 33.8 0.0 8.3 8 1 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 PRP88441.1 - 1.2e-11 44.9 1.5 3.1e-06 27.5 0.0 6.7 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.22 PRP88441.1 - 1.1e-09 37.7 0.1 0.011 16.0 0.0 8.3 9 0 0 9 9 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 PRP88441.1 - 1.4e-08 35.2 0.2 0.00016 22.2 0.0 6.1 5 2 2 7 7 7 1 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 PRP88441.1 - 3.5e-08 33.5 2.5 1.7e-06 28.1 0.1 4.0 4 0 0 4 4 4 1 Importin repeat 6 DUF3385 PF11865.8 PRP88441.1 - 8.1e-06 25.8 5.0 1.8 8.4 0.0 7.4 4 3 2 7 7 7 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 PRP88441.1 - 0.00018 21.6 8.3 0.48 10.5 0.2 4.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 PRP88441.1 - 0.00039 20.6 1.8 0.69 10.0 0.2 5.3 5 1 0 6 6 6 1 Parkin co-regulated protein RIX1 PF08167.12 PRP88441.1 - 0.0005 19.9 1.1 1.6 8.4 0.1 4.5 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis IBN_N PF03810.19 PRP88441.1 - 0.0018 18.2 0.4 0.036 14.0 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Sec7_N PF12783.7 PRP88441.1 - 0.026 14.4 4.6 20 5.0 0.1 4.6 4 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CTD_bind PF04818.13 PRP88441.1 - 0.059 14.2 0.1 61 4.6 0.0 5.7 7 0 0 7 7 7 0 RNA polymerase II-binding domain. MOZART1 PF12554.8 PRP88442.1 - 5.8e-15 54.8 0.4 6.7e-15 54.6 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SLATT_4 PF18186.1 PRP88443.1 - 0.046 13.4 0.4 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 EbsA PF17255.2 PRP88443.1 - 1.4 9.3 4.9 6.5 7.1 0.0 3.0 3 0 0 3 3 3 0 EbsA-like protein HATPase_c PF02518.26 PRP88444.1 - 3.5e-32 111.2 0.2 2.5e-31 108.5 0.6 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP88444.1 - 1.3e-23 83.3 0.8 5.1e-23 81.4 0.8 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 PRP88444.1 - 8.6e-19 67.3 0.1 3.2e-18 65.5 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP88444.1 - 0.022 14.6 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 PRP88444.1 - 0.024 14.6 0.1 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 GHKL domain Vps52 PF04129.12 PRP88445.1 - 5.1e-105 352.1 19.1 5.1e-105 352.1 19.1 1.5 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.9 PRP88445.1 - 2.7e-09 36.0 3.1 2.7e-09 36.0 3.1 2.7 2 1 0 2 2 2 1 Exocyst complex component Sec3 DUF1664 PF07889.12 PRP88445.1 - 0.015 15.3 3.3 0.093 12.8 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) WEMBL PF05701.11 PRP88445.1 - 0.039 12.6 0.6 0.064 11.9 0.6 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light APG17 PF04108.12 PRP88445.1 - 4.2 6.4 12.5 0.045 12.9 1.1 3.0 3 1 1 4 4 4 0 Autophagy protein Apg17 aGPT-Pplase1 PF18723.1 PRP88446.1 - 7.3e-55 186.4 3.0 2.7e-54 184.5 3.0 1.8 1 1 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 PRP88446.1 - 5e-08 32.7 3.2 2.5e-07 30.5 3.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 PRP88446.1 - 0.00023 21.2 0.1 0.0011 19.0 0.2 2.0 2 0 0 2 2 2 1 Chromo shadow domain Cys_Met_Meta_PP PF01053.20 PRP88448.1 - 9.8e-153 508.2 0.0 1.1e-152 508.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 PRP88448.1 - 7.3e-08 32.0 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PRP88448.1 - 0.0062 15.5 0.0 0.015 14.3 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PRP88448.1 - 0.043 13.1 0.0 0.15 11.3 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase LCAT PF02450.15 PRP88451.1 - 4.5e-58 197.3 0.0 1e-45 156.6 0.0 3.2 2 1 1 3 3 3 2 Lecithin:cholesterol acyltransferase PX PF00787.24 PRP88451.1 - 7.9e-16 58.0 0.3 1.7e-15 57.0 0.3 1.6 1 0 0 1 1 1 1 PX domain C2 PF00168.30 PRP88451.1 - 1.2e-12 48.0 0.2 1.9e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain PH PF00169.29 PRP88451.1 - 5.7e-08 33.2 0.0 2.8e-07 31.0 0.0 2.3 1 0 0 1 1 1 1 PH domain PGAP1 PF07819.13 PRP88451.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein PH_16 PF17838.1 PRP88451.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 PH domain DUF676 PF05057.14 PRP88451.1 - 0.089 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF4299 PF14132.6 PRP88451.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4299) DUF900 PF05990.12 PRP88451.1 - 0.2 11.1 0.0 0.42 10.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2989 PF11207.8 PRP88452.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) G8 PF10162.9 PRP88454.1 - 1.9e-20 73.2 0.1 5.9e-20 71.6 0.1 1.9 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP88454.1 - 0.022 14.6 16.4 0.019 14.8 2.6 4.2 4 2 0 4 4 4 0 Right handed beta helix region DUF2190 PF09956.9 PRP88454.1 - 0.11 13.0 0.8 4.4 7.8 0.4 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2190) MCM PF00493.23 PRP88455.1 - 4.2e-104 346.5 0.1 7.2e-104 345.8 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PRP88455.1 - 6.7e-33 113.2 0.0 1.2e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PRP88455.1 - 1e-27 96.3 1.8 1.7e-27 95.7 0.6 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 PRP88455.1 - 2.1e-17 63.6 0.0 5.2e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PRP88455.1 - 1.2e-06 28.1 0.1 0.00029 20.3 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PRP88455.1 - 1.4e-05 25.1 0.0 4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 PRP88455.1 - 1.9e-05 24.5 0.0 9.8e-05 22.2 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PRP88455.1 - 0.023 14.4 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NAD_binding_4 PF07993.12 PRP88456.1 - 4.2e-64 216.2 0.0 8.3e-64 215.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 PRP88456.1 - 2e-20 72.8 0.0 4.4e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 PRP88456.1 - 1.2e-14 54.2 0.7 5.6e-14 52.1 1.0 2.0 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 PRP88456.1 - 3.4e-06 26.7 0.0 1.2e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PRP88456.1 - 0.0016 17.7 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 PRP88456.1 - 0.0052 15.8 0.5 0.021 13.8 0.5 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PRP88456.1 - 0.0059 16.1 0.1 1 8.7 0.0 2.5 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Ribonuc_red_2_N PF08471.10 PRP88456.1 - 0.097 12.9 0.0 2.6 8.3 0.0 2.7 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Arrestin_C PF02752.22 PRP88457.1 - 1.5e-17 64.3 0.1 1.6e-11 44.8 0.0 2.4 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 PRP88457.1 - 1.1e-07 32.0 0.2 0.00023 21.2 0.1 3.2 2 2 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain MG2 PF01835.19 PRP88457.1 - 0.00014 22.2 0.0 0.1 13.1 0.0 2.4 2 0 0 2 2 2 2 MG2 domain Rgp1 PF08737.10 PRP88457.1 - 0.056 12.6 0.0 1.2 8.2 0.0 2.5 3 0 0 3 3 3 0 Rgp1 CH PF00307.31 PRP88458.1 - 3e-37 127.1 0.5 4e-20 72.0 0.6 2.5 3 0 0 3 3 3 2 Calponin homology (CH) domain Filamin PF00630.19 PRP88458.1 - 3.5e-17 63.1 0.0 7.1e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat YtkA PF13115.6 PRP88458.1 - 0.0032 18.0 0.1 0.0076 16.8 0.1 1.7 1 0 0 1 1 1 1 YtkA-like CH_2 PF06294.11 PRP88458.1 - 0.0037 17.3 0.2 2.9 8.1 0.1 2.3 2 0 0 2 2 2 2 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PRP88458.1 - 0.0052 16.6 0.0 0.49 10.3 0.0 2.6 2 1 0 2 2 2 1 CAMSAP CH domain Glyco_transf_88 PF16849.5 PRP88458.1 - 0.016 14.2 0.2 0.037 13.0 0.1 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 88 Glutaredoxin PF00462.24 PRP88458.1 - 0.036 14.3 0.2 0.12 12.6 0.1 1.9 2 0 0 2 2 2 0 Glutaredoxin Y_Y_Y PF07495.13 PRP88458.1 - 0.057 13.4 0.4 0.58 10.1 0.1 2.5 2 1 0 2 2 2 0 Y_Y_Y domain Kinesin PF00225.23 PRP88459.1 - 7.1e-108 360.5 0.3 7.1e-108 360.5 0.3 2.7 2 1 1 3 3 3 1 Kinesin motor domain Kinesin_assoc PF16183.5 PRP88459.1 - 1.5e-25 90.4 3.9 3.3e-21 76.2 1.1 6.4 4 2 2 7 7 7 2 Kinesin-associated Microtub_bd PF16796.5 PRP88459.1 - 4.2e-24 85.2 0.0 4.2e-24 85.2 0.0 3.1 4 0 0 4 4 4 1 Microtubule binding PH PF00169.29 PRP88459.1 - 1.2e-18 67.5 1.4 2.8e-17 63.1 0.4 3.2 3 0 0 3 3 3 1 PH domain FHA PF00498.26 PRP88459.1 - 1.6e-05 25.2 0.0 0.00028 21.2 0.0 3.0 2 0 0 2 2 2 1 FHA domain PH_8 PF15409.6 PRP88459.1 - 0.0054 17.0 0.1 0.018 15.3 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3694 PF12473.8 PRP88459.1 - 0.0063 17.2 4.1 0.011 16.4 0.0 3.4 3 1 0 3 3 3 1 Kinesin protein PH_11 PF15413.6 PRP88459.1 - 0.054 13.9 5.6 0.47 10.9 5.6 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain Terminase_6C PF17289.2 PRP88459.1 - 0.15 12.1 5.6 0.12 12.4 1.0 3.0 3 1 0 3 3 3 0 Terminase RNaseH-like domain zf-C2H2 PF00096.26 PRP88460.1 - 0.0068 16.8 1.9 0.013 15.9 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP88460.1 - 0.026 15.3 1.8 0.055 14.3 1.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PRP88460.1 - 0.1 12.4 1.9 0.17 11.7 1.9 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type Lectin_C_term PF18022.1 PRP88460.1 - 0.14 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain GAS PF13851.6 PRP88461.1 - 0.021 14.2 3.9 0.031 13.6 3.9 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4757 PF15949.5 PRP88461.1 - 2.4 8.6 11.8 3.3 8.1 4.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4757) Carboxyl_trans PF01039.22 PRP88462.1 - 8.6e-120 400.7 0.0 1.2e-119 400.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ECH_1 PF00378.20 PRP88462.1 - 0.1 11.9 0.8 9 5.5 0.0 2.4 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase MdcE PF06833.11 PRP88462.1 - 0.13 11.7 0.1 20 4.5 0.1 2.7 2 1 1 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) R3H PF01424.22 PRP88463.1 - 6.4e-07 29.3 0.2 2.4e-06 27.4 0.0 2.1 3 0 0 3 3 3 1 R3H domain Orthoreo_P10 PF07204.11 PRP88463.1 - 0.021 14.8 0.2 0.038 14.0 0.2 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF3394 PF11874.8 PRP88463.1 - 0.15 11.7 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) Ras PF00071.22 PRP88464.1 - 7.7e-53 178.4 0.1 1e-52 178.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88464.1 - 2.3e-21 76.2 0.1 3.6e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP88464.1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP88464.1 - 0.00014 21.5 0.4 0.00097 18.7 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP88464.1 - 0.00037 20.6 0.1 0.00061 19.9 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP88464.1 - 0.00055 19.9 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Alpha-amylase PF00128.24 PRP88465.1 - 1.1e-24 87.7 0.9 3.1e-24 86.2 0.9 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 PRP88465.1 - 5.2e-05 22.5 0.8 0.00083 18.6 0.0 2.2 2 0 0 2 2 2 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 PRP88465.1 - 0.00035 21.0 0.2 0.0095 16.4 0.0 2.8 2 1 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Malt_amylase_C PF16657.5 PRP88465.1 - 0.087 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Glyco_hydro_42C PF08533.10 PRP88465.1 - 0.12 12.1 0.3 1.2 8.9 0.1 2.3 1 1 1 2 2 2 0 Beta-galactosidase C-terminal domain S1-P1_nuclease PF02265.16 PRP88466.1 - 5e-52 177.2 0.0 5.7e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF4248 PF14053.6 PRP88466.1 - 0.0068 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4248) Glyco_hydro_20 PF00728.22 PRP88467.1 - 7.9e-23 81.4 0.0 1.6e-21 77.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 PRP88467.1 - 5e-05 24.1 0.0 0.00013 22.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 PRP88467.1 - 0.00081 20.1 0.0 0.0018 18.9 0.0 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Alpha-amylase PF00128.24 PRP88468.1 - 2.9e-14 53.4 0.3 6.8e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PRP88468.1 - 7.5e-13 48.8 0.4 3.2e-12 46.8 0.4 2.2 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain TMEM132D_C PF15706.5 PRP88468.1 - 0.0099 15.6 0.0 0.74 9.6 0.0 2.5 2 0 0 2 2 2 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM51 PF15345.6 PRP88468.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2807 PF10988.8 PRP88468.1 - 0.23 11.2 1.8 2 8.2 0.3 2.5 2 0 0 2 2 2 0 Putative auto-transporter adhesin, head GIN domain Uso1_p115_head PF04869.14 PRP88469.1 - 4.1e-49 167.4 1.9 1.2e-48 165.8 1.9 1.9 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region SlyX PF04102.12 PRP88469.1 - 0.04 14.5 0.2 0.04 14.5 0.2 5.5 3 1 1 4 4 4 0 SlyX RSS_P20 PF11757.8 PRP88469.1 - 3.5 8.1 7.0 18 5.8 0.3 3.1 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain G8 PF10162.9 PRP88470.1 - 3.7e-17 62.5 0.6 9e-17 61.3 0.6 1.7 1 0 0 1 1 1 1 G8 domain Beta_helix PF13229.6 PRP88470.1 - 0.00058 19.7 12.0 0.0022 17.8 0.6 3.6 4 0 0 4 4 4 2 Right handed beta helix region eIF-6 PF01912.18 PRP88471.1 - 5.1e-80 267.5 0.6 1.1e-79 266.5 0.3 1.5 2 0 0 2 2 2 1 eIF-6 family Sec23_trunk PF04811.15 PRP88472.1 - 8.8e-72 241.6 0.1 2e-71 240.4 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 PRP88472.1 - 1.5e-28 98.6 0.2 4.2e-28 97.2 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 PRP88472.1 - 5.9e-19 68.6 0.4 1.1e-18 67.8 0.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 PRP88472.1 - 3.6e-17 62.1 3.3 9.1e-17 60.8 3.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 PRP88472.1 - 8.8e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat GST_N_2 PF13409.6 PRP88473.1 - 1.5e-08 34.8 0.0 3.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PRP88473.1 - 1.3e-07 31.9 0.0 3.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Dpoe2NT PF12213.8 PRP88473.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal START PF01852.19 PRP88475.1 - 0.0015 18.0 0.0 0.0015 18.0 0.0 2.0 3 0 0 3 3 3 1 START domain Pkinase_Tyr PF07714.17 PRP88476.1 - 1.5e-32 112.9 0.0 2.2e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88476.1 - 2.1e-20 73.2 0.0 3.4e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP88476.1 - 8.3e-17 60.7 24.3 2.5e-07 30.3 5.0 6.4 5 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PRP88476.1 - 6.1e-13 48.7 33.6 3.2e-05 24.2 6.4 6.1 4 2 1 6 6 6 5 Leucine Rich repeats (2 copies) GPS PF01825.21 PRP88476.1 - 3.6e-10 40.2 3.3 1e-09 38.8 3.3 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_1 PF00560.33 PRP88476.1 - 2e-07 30.6 26.0 0.36 11.6 0.5 8.4 8 0 0 8 8 8 4 Leucine Rich Repeat Kinase-like PF14531.6 PRP88476.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CRAL_TRIO PF00650.20 PRP88479.1 - 7.2e-13 48.5 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Glyco_hydro_16 PF00722.21 PRP88480.1 - 2.3e-25 89.1 0.5 4.2e-25 88.2 0.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 X8 PF07983.13 PRP88480.1 - 5.8e-10 39.7 5.2 1.6e-09 38.3 5.2 1.8 1 0 0 1 1 1 1 X8 domain Carb_bind PF10645.9 PRP88480.1 - 0.007 16.6 13.5 0.007 16.6 13.5 2.7 2 1 1 3 3 3 2 Carbohydrate binding G-patch PF01585.23 PRP88480.1 - 0.022 14.6 1.1 0.049 13.5 1.1 1.6 1 0 0 1 1 1 0 G-patch domain X8 PF07983.13 PRP88481.1 - 2.6e-54 181.8 52.1 1.2e-09 38.7 1.6 6.8 7 0 0 7 7 7 6 X8 domain DUF2989 PF11207.8 PRP88481.1 - 0.00011 22.1 4.6 4.4 7.0 0.0 6.1 7 0 0 7 7 7 2 Protein of unknown function (DUF2989) DUF226 PF02890.14 PRP88481.1 - 0.014 15.4 0.4 11 6.0 0.0 3.4 3 0 0 3 3 3 0 Borrelia family of unknown function DUF226 AMP-binding PF00501.28 PRP88483.1 - 3.1e-81 273.1 0.0 4.1e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP88483.1 - 1.8e-19 70.5 0.3 3.7e-19 69.5 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 PRP88483.1 - 0.0089 14.9 0.0 0.029 13.2 0.0 1.7 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RAD51_interact PF15696.5 PRP88484.1 - 0.32 11.1 1.7 0.56 10.4 0.1 2.4 2 0 0 2 2 2 0 RAD51 interacting motif OHCU_decarbox PF09349.10 PRP88485.1 - 1.5e-36 126.2 0.3 1.7e-36 126.0 0.3 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF5446 PF17522.2 PRP88485.1 - 0.1 12.8 2.6 0.11 12.7 0.0 2.3 3 1 0 3 3 3 0 Family of unknown function (DUF5446) Y_phosphatase3 PF13350.6 PRP88486.1 - 7.4e-40 137.4 0.0 1e-39 136.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 PRP88486.1 - 4.2e-08 33.0 0.0 1.5e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase PF00102.27 PRP88486.1 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 PRP88486.1 - 0.038 12.9 0.1 0.066 12.1 0.1 1.5 1 1 0 1 1 1 0 Myotubularin-like phosphatase domain F-box-like PF12937.7 PRP88489.1 - 0.00019 21.3 1.1 0.00022 21.1 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP88489.1 - 0.008 16.0 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.7 PRP88491.1 - 1.3e-22 80.2 0.0 4e-11 43.3 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP88491.1 - 6.8e-15 54.9 0.0 0.00046 20.4 0.0 6.3 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88491.1 - 1.7e-14 52.4 0.0 0.057 14.0 0.0 7.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 PRP88491.1 - 1.5e-12 47.8 0.0 0.00018 22.0 0.0 6.5 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP88491.1 - 8.6e-11 41.8 0.1 0.11 13.0 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat SgrT PF15894.5 PRP88491.1 - 0.0038 17.2 0.1 4.6 7.3 0.0 2.7 2 0 0 2 2 2 2 Inhibitor of glucose uptake transporter SgrT CBM_15 PF03426.14 PRP88491.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 15) Peptidase_M16_C PF05193.21 PRP88491.1 - 0.073 13.1 0.1 6.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Peptidase M16 inactive domain zf-CCCH_4 PF18044.1 PRP88494.1 - 1.2e-06 28.2 4.0 2.4e-06 27.2 4.0 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PRP88494.1 - 0.00017 21.5 3.6 0.00037 20.4 3.6 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PRP88494.1 - 0.02 14.8 2.8 0.037 14.0 2.8 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PRP88494.1 - 0.02 15.6 0.1 0.048 14.4 0.1 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH_3 PF15663.5 PRP88494.1 - 0.033 14.4 0.1 0.065 13.5 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 PRP88494.1 - 0.04 14.4 4.6 0.082 13.4 4.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger HATPase_c PF02518.26 PRP88495.1 - 4.8e-27 94.7 0.2 1.2e-26 93.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP88495.1 - 1.3e-24 86.5 0.0 3.8e-24 85.0 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.6 PRP88495.1 - 3.7e-24 86.0 0.0 1.3e-23 84.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP88495.1 - 5.4e-15 55.5 0.1 1.3e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88495.1 - 9.1e-13 48.1 0.1 1.9e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HisKA PF00512.25 PRP88495.1 - 4.1e-10 39.5 0.0 7.3e-09 35.5 0.0 3.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 PRP88495.1 - 4.7e-06 27.3 0.0 1.1e-05 26.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain AAA_22 PF13401.6 PRP88495.1 - 0.00086 19.6 0.4 0.0066 16.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain HATPase_c_3 PF13589.6 PRP88495.1 - 0.002 17.9 0.2 0.006 16.4 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF815 PF05673.13 PRP88495.1 - 0.0021 17.3 0.0 0.0063 15.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 PRP88495.1 - 0.0052 16.8 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Kdo PF06293.14 PRP88495.1 - 0.0055 16.1 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RsgA_GTPase PF03193.16 PRP88495.1 - 0.015 15.2 0.0 0.053 13.4 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase EcoR124_C PF12008.8 PRP88495.1 - 0.027 14.1 1.7 0.09 12.4 1.3 2.1 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal ATPase_2 PF01637.18 PRP88495.1 - 0.031 14.2 1.4 0.049 13.5 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 PRP88495.1 - 0.045 13.7 0.0 0.91 9.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 PRP88495.1 - 0.067 12.5 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.6 PRP88495.1 - 0.084 12.9 0.1 0.36 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain HATPase_c_5 PF14501.6 PRP88495.1 - 0.43 10.5 3.1 1.2 9.1 0.5 3.1 2 1 0 2 2 2 0 GHKL domain Pkinase_Tyr PF07714.17 PRP88496.1 - 1.3e-66 224.5 0.0 8.5e-66 221.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88496.1 - 4.7e-47 160.6 0.0 6.7e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP88496.1 - 0.0076 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP88496.1 - 0.067 12.0 0.1 0.15 10.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Stevor PF17410.2 PRP88496.1 - 0.16 11.5 0.6 0.24 10.9 0.6 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame LRR_8 PF13855.6 PRP88497.1 - 3.9e-42 141.8 108.2 2.3e-08 33.7 0.1 16.3 9 5 9 19 19 19 16 Leucine rich repeat LRR_4 PF12799.7 PRP88497.1 - 8.4e-36 121.4 109.7 0.00067 20.0 0.7 19.7 10 7 12 23 23 23 19 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP88497.1 - 1.1e-10 40.5 99.1 1.1 10.1 0.0 27.3 29 4 0 29 29 29 5 Leucine Rich Repeat LRR_6 PF13516.6 PRP88497.1 - 1.2e-10 40.6 90.0 3.1 8.1 0.7 25.5 27 2 2 29 29 29 7 Leucine Rich repeat DUF5612 PF18462.1 PRP88497.1 - 0.11 12.3 0.1 14 5.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5612) Prefoldin PF02996.17 PRP88498.1 - 3.7e-18 65.6 6.4 3.7e-18 65.6 6.4 1.5 1 1 0 1 1 1 1 Prefoldin subunit AAA_18 PF13238.6 PRP88499.1 - 0.01 16.4 0.0 0.13 12.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PRP88499.1 - 0.047 14.1 0.0 0.085 13.2 0.0 1.6 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 PRP88499.1 - 0.066 13.6 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase T2SSE PF00437.20 PRP88499.1 - 0.12 11.4 0.2 0.72 8.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Cofilin_ADF PF00241.20 PRP88500.1 - 8.4e-27 93.4 0.0 1.9e-25 89.0 0.0 2.3 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein EF-hand_1 PF00036.32 PRP88500.1 - 1.1e-13 49.6 2.5 1e-05 24.7 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PRP88500.1 - 2.2e-13 50.5 0.7 8e-10 39.0 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP88500.1 - 2.7e-12 45.5 5.2 0.00053 19.7 0.1 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 PRP88500.1 - 8.4e-10 37.7 3.2 0.00026 20.3 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PRP88500.1 - 8.6e-09 35.1 0.3 2.6e-07 30.4 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PRP88500.1 - 0.0013 19.1 0.4 2.6 8.4 0.0 3.1 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region NUDIX PF00293.28 PRP88501.1 - 2e-07 31.1 0.2 4.3e-07 30.0 0.2 1.6 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.32 PRP88502.1 - 2e-46 155.0 21.9 7.3e-09 36.1 0.2 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP88502.1 - 1.2e-13 51.1 1.4 0.12 12.7 0.0 6.3 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 PRP88502.1 - 2.7e-08 33.3 1.5 0.0048 16.0 0.0 3.6 2 1 1 3 3 3 2 Coatomer WD associated region WD40_like PF17005.5 PRP88502.1 - 3.9e-06 26.4 0.5 0.046 13.0 0.0 3.7 3 2 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 PRP88502.1 - 0.00039 19.2 5.6 0.14 10.7 0.1 4.8 2 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PRP88502.1 - 0.0025 16.9 0.2 0.32 9.9 0.0 3.5 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 PRP88502.1 - 0.02 15.4 0.2 18 6.0 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 PRP88502.1 - 0.039 13.9 0.1 20 5.3 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat LisH PF08513.11 PRP88502.1 - 0.048 13.6 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 LisH CSD PF00313.22 PRP88504.1 - 9.1e-58 192.0 4.8 1.6e-09 37.5 0.3 8.9 8 0 0 8 8 8 7 'Cold-shock' DNA-binding domain EF-hand_1 PF00036.32 PRP88504.1 - 1.1e-11 43.4 1.2 2.2e-05 23.7 0.5 3.6 3 0 0 3 3 3 2 EF hand S1-like PF14444.6 PRP88504.1 - 6.1e-10 38.9 6.3 0.017 15.1 0.1 6.1 6 0 0 6 6 6 2 S1-like EF-hand_7 PF13499.6 PRP88504.1 - 1.2e-08 35.3 0.0 9.3e-05 22.8 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP88504.1 - 3.1e-08 32.9 0.9 0.0094 15.8 0.2 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP88504.1 - 7.4e-06 25.2 0.4 0.014 14.9 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PRP88504.1 - 5.3e-05 23.0 0.1 0.018 14.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair Rho_RNA_bind PF07497.12 PRP88504.1 - 0.00013 21.7 0.7 36 4.3 0.0 6.1 7 0 0 7 7 7 0 Rho termination factor, RNA-binding domain OB_RNB PF08206.11 PRP88504.1 - 0.008 15.8 11.1 13 5.5 0.0 5.3 5 0 0 5 5 5 2 Ribonuclease B OB domain DUF2196 PF09962.9 PRP88504.1 - 0.056 13.4 0.4 3.8 7.6 0.0 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2196) WD40 PF00400.32 PRP88505.1 - 0.00041 21.1 6.7 1.3 10.0 0.0 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP88505.1 - 0.0085 16.4 0.0 1.1 9.6 0.0 3.4 3 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Polyhedrin PF00738.18 PRP88507.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Polyhedrin Ribosomal_L27A PF00828.19 PRP88508.1 - 5.7e-32 111.1 2.4 1.1e-31 110.2 2.4 1.5 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Spermine_synth PF01564.17 PRP88509.1 - 2.2e-45 154.4 0.1 3.3e-45 153.8 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PRP88509.1 - 1.4e-07 31.3 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 PRP88509.1 - 2.8e-06 27.9 0.0 7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP88509.1 - 0.00062 20.5 0.0 0.0021 18.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP88509.1 - 0.001 19.7 0.0 0.0035 18.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP88509.1 - 0.0075 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP88509.1 - 0.0089 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF43 PF01861.16 PRP88509.1 - 0.01 15.1 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_24 PF13578.6 PRP88509.1 - 0.014 16.4 0.0 0.034 15.2 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 PRP88509.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family PRMT5 PF05185.16 PRP88509.1 - 0.029 14.2 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_30 PF05430.11 PRP88509.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase TrkA_N PF02254.18 PRP88509.1 - 0.19 12.0 1.1 0.73 10.1 0.3 2.3 2 1 1 3 3 3 0 TrkA-N domain DUF1754 PF08555.10 PRP88510.1 - 0.0035 18.1 13.1 0.067 14.0 6.7 3.0 1 1 2 3 3 3 2 Eukaryotic family of unknown function (DUF1754) Mcm10 PF09332.11 PRP88510.1 - 0.048 13.1 5.9 0.06 12.8 5.9 1.0 1 0 0 1 1 1 0 Mcm10 replication factor YqfD PF06898.11 PRP88510.1 - 0.084 11.7 1.7 0.097 11.5 1.7 1.0 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD RIX1 PF08167.12 PRP88511.1 - 2.1e-20 73.3 3.7 2.1e-20 73.3 3.7 3.2 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Coilin_N PF15862.5 PRP88511.1 - 0.013 15.3 2.4 0.013 15.3 2.4 3.3 3 0 0 3 3 3 0 Coilin N-terminus BTG PF07742.12 PRP88513.1 - 3.3e-21 75.3 0.0 5.1e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 BTG family BolA PF01722.18 PRP88514.1 - 6.8e-13 48.7 0.2 2.3e-12 47.0 0.1 1.8 1 1 2 3 3 3 1 BolA-like protein BolA PF01722.18 PRP88517.1 - 7.9e-13 48.5 0.2 2.7e-12 46.8 0.1 1.8 1 1 2 3 3 3 1 BolA-like protein BTG PF07742.12 PRP88518.1 - 3.3e-21 75.3 0.0 5.1e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 BTG family RIX1 PF08167.12 PRP88520.1 - 2.1e-20 73.3 3.7 2.1e-20 73.3 3.7 3.2 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Coilin_N PF15862.5 PRP88520.1 - 0.013 15.3 2.4 0.013 15.3 2.4 3.3 3 0 0 3 3 3 0 Coilin N-terminus DUF1754 PF08555.10 PRP88521.1 - 0.0035 18.1 13.1 0.067 14.0 6.7 3.0 1 1 2 3 3 3 2 Eukaryotic family of unknown function (DUF1754) Mcm10 PF09332.11 PRP88521.1 - 0.048 13.1 5.9 0.06 12.8 5.9 1.0 1 0 0 1 1 1 0 Mcm10 replication factor YqfD PF06898.11 PRP88521.1 - 0.084 11.7 1.7 0.097 11.5 1.7 1.0 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Spermine_synth PF01564.17 PRP88522.1 - 2.2e-45 154.4 0.1 3.3e-45 153.8 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PRP88522.1 - 1.4e-07 31.3 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 PRP88522.1 - 2.8e-06 27.9 0.0 7e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP88522.1 - 0.00062 20.5 0.0 0.0021 18.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP88522.1 - 0.001 19.7 0.0 0.0035 18.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP88522.1 - 0.0075 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PRP88522.1 - 0.0089 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF43 PF01861.16 PRP88522.1 - 0.01 15.1 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_24 PF13578.6 PRP88522.1 - 0.014 16.4 0.0 0.034 15.2 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 PRP88522.1 - 0.018 14.6 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family PRMT5 PF05185.16 PRP88522.1 - 0.029 14.2 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_30 PF05430.11 PRP88522.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase TrkA_N PF02254.18 PRP88522.1 - 0.19 12.0 1.1 0.73 10.1 0.3 2.3 2 1 1 3 3 3 0 TrkA-N domain Ribosomal_L27A PF00828.19 PRP88523.1 - 5.8e-32 111.1 2.4 1.1e-31 110.1 2.4 1.5 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Polyhedrin PF00738.18 PRP88524.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Polyhedrin WD40 PF00400.32 PRP88525.1 - 0.0018 19.1 8.2 1.4 10.0 0.0 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP88525.1 - 0.009 16.3 0.0 1.1 9.6 0.0 3.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CSD PF00313.22 PRP88526.1 - 1.2e-32 111.6 0.0 1.9e-09 37.2 0.0 5.1 5 0 0 5 5 5 4 'Cold-shock' DNA-binding domain EF-hand_1 PF00036.32 PRP88526.1 - 3.2e-12 45.1 1.2 1.4e-05 24.3 0.5 3.6 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PRP88526.1 - 4.9e-09 36.5 0.0 6e-05 23.4 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP88526.1 - 8.8e-09 34.6 0.9 0.0061 16.4 0.2 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP88526.1 - 2.9e-06 26.5 0.4 0.0093 15.4 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PRP88526.1 - 2.2e-05 24.2 0.1 0.011 15.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair S1-like PF14444.6 PRP88526.1 - 0.0044 16.9 0.4 17 5.4 0.0 3.7 3 0 0 3 3 3 1 S1-like Rho_RNA_bind PF07497.12 PRP88526.1 - 0.031 14.1 0.1 24 4.9 0.0 3.3 3 0 0 3 3 3 0 Rho termination factor, RNA-binding domain DUF2196 PF09962.9 PRP88526.1 - 0.073 13.1 1.5 2.5 8.2 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2196) OB_RNB PF08206.11 PRP88526.1 - 0.14 11.9 3.4 8.9 6.1 0.0 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain Chitin_bind_1 PF00187.19 PRP88527.1 - 2.2e-07 31.2 20.6 2.2e-07 31.2 20.6 3.3 5 0 0 5 5 5 1 Chitin recognition protein Abhydrolase_1 PF00561.20 PRP88528.1 - 0.00015 21.5 0.0 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PRP88528.1 - 0.00018 20.8 0.0 0.00053 19.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP88528.1 - 0.16 12.6 0.0 0.36 11.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family RPE65 PF03055.15 PRP88529.1 - 2.3e-94 317.2 0.7 2.9e-94 316.9 0.7 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Peptidase_C12 PF01088.21 PRP88530.1 - 1.9e-29 102.9 0.0 4.1e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Methyltransf_21 PF05050.12 PRP88530.1 - 1.2e-10 41.7 0.0 2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Arg_decarbox_C PF17944.1 PRP88530.1 - 0.093 13.3 0.2 0.5 11.0 0.1 2.3 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension TRAPPC-Trs85 PF12739.7 PRP88533.1 - 5.6e-63 213.3 0.1 8.5e-58 196.2 0.0 2.8 2 1 1 3 3 3 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Transglut_C PF00927.22 PRP88533.1 - 1.4e-08 34.8 2.5 0.0039 17.3 0.0 4.1 3 1 1 4 4 4 2 Transglutaminase family, C-terminal ig like domain TRAPPC9-Trs120 PF08626.11 PRP88533.1 - 0.00092 16.7 0.0 0.0015 16.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_2 PF07719.17 PRP88533.1 - 0.054 13.6 0.1 4.9 7.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 PRP88537.1 - 3.4e-26 90.8 0.1 4.5e-26 90.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 PRP88537.1 - 4e-05 23.4 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 PRP88537.1 - 0.00056 20.0 0.1 0.00072 19.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Spidroin_N PF16763.5 PRP88537.1 - 0.1 12.7 1.3 4.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term HPP PF04982.13 PRP88538.1 - 9.1e-44 148.6 3.2 1.6e-43 147.7 3.2 1.4 1 0 0 1 1 1 1 HPP family DUF2427 PF10348.9 PRP88538.1 - 0.01 15.6 0.4 0.027 14.2 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Ank_4 PF13637.6 PRP88539.1 - 9.5e-20 70.7 9.3 0.0061 17.1 0.0 8.1 3 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP88539.1 - 7.6e-11 42.4 1.4 0.14 12.8 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP88539.1 - 1.2e-06 28.6 9.9 17 5.8 0.1 8.2 6 3 5 11 11 11 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88539.1 - 2.5e-05 24.3 4.4 4.3 8.2 0.0 7.9 11 0 0 11 11 11 1 Ankyrin repeat F-box PF00646.33 PRP88539.1 - 0.0022 17.8 0.6 0.0061 16.4 0.1 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PRP88539.1 - 0.03 14.2 0.2 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 F-box-like PPR_2 PF13041.6 PRP88539.1 - 0.047 13.9 0.0 6.6 7.0 0.0 4.0 6 0 0 6 6 6 0 PPR repeat family zf-TRAF PF02176.18 PRP88539.1 - 0.065 13.9 2.8 50 4.7 0.0 4.2 3 2 1 4 4 4 0 TRAF-type zinc finger Pro-kuma_activ PF09286.11 PRP88540.1 - 4e-31 108.2 0.8 9.3e-31 107.0 0.8 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Asp PF00026.23 PRP88541.1 - 1.3e-27 97.0 6.3 2.2e-27 96.3 6.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Linker_histone PF00538.19 PRP88541.1 - 1.5e-08 34.9 0.1 3.7e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family TAXi_C PF14541.6 PRP88541.1 - 9.4e-08 32.0 0.1 2.8e-06 27.2 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 PRP88541.1 - 2.2e-07 31.3 0.1 1e-05 25.8 0.1 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal BatA PF07584.11 PRP88541.1 - 0.037 14.4 0.1 0.08 13.3 0.1 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal DUF4625 PF15418.6 PRP88541.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4625) Asp_protease_2 PF13650.6 PRP88541.1 - 0.099 13.3 0.0 17 6.1 0.0 3.0 2 0 0 2 2 2 0 Aspartyl protease BTB_2 PF02214.22 PRP88542.1 - 5.4e-09 36.3 0.2 1.3e-08 35.1 0.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain MIR PF02815.19 PRP88543.1 - 2.2e-18 66.8 0.1 8e-18 64.9 0.0 1.9 1 1 1 2 2 2 2 MIR domain RhoGAP PF00620.27 PRP88545.1 - 3.2e-25 88.7 0.1 3.2e-25 88.7 0.1 3.3 3 1 0 3 3 3 1 RhoGAP domain TMF_TATA_bd PF12325.8 PRP88545.1 - 0.019 15.2 33.6 0.55 10.5 20.8 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PKcGMP_CC PF16808.5 PRP88545.1 - 0.23 11.3 22.4 0.044 13.6 1.8 4.3 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 PRP88545.1 - 0.38 9.8 27.9 0.04 13.0 6.9 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 HrpB7 PF09486.10 PRP88545.1 - 0.61 10.5 16.3 1.4 9.3 10.1 3.1 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMEM192 PF14802.6 PRP88545.1 - 0.74 8.9 3.5 3.2 6.8 2.7 2.2 2 0 0 2 2 2 0 TMEM192 family LuxT_C PF18285.1 PRP88545.1 - 1.6 9.3 5.2 1.9 9.1 0.1 3.1 3 1 1 4 4 4 0 Tetracycline repressor LuxT C-terminal domain GNT-I PF03071.15 PRP88545.1 - 4.2 6.0 8.6 7.5 5.2 8.6 1.3 1 0 0 1 1 1 0 GNT-I family CENP-Q PF13094.6 PRP88545.1 - 7.9 6.7 28.1 8.7 6.5 2.6 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit UPF0160 PF03690.13 PRP88546.1 - 1.4e-131 438.9 0.1 1.5e-131 438.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) tRNA_edit PF04073.15 PRP88548.1 - 1.9e-07 31.2 0.0 4.8e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Memo PF01875.17 PRP88550.1 - 3.6e-85 285.4 0.0 4.1e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Pkinase PF00069.25 PRP88552.1 - 1.3e-70 237.8 0.0 2e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88552.1 - 3.1e-36 125.0 0.1 6.7e-36 123.9 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 PRP88552.1 - 2.8e-05 23.3 3.2 2.8e-05 23.3 3.2 2.0 2 1 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 PRP88552.1 - 0.0017 17.2 0.1 0.012 14.4 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP88552.1 - 0.0018 17.7 2.4 0.0033 16.8 0.0 2.3 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.14 PRP88552.1 - 0.013 14.8 0.5 0.025 14.0 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Carb_bind PF10645.9 PRP88553.1 - 0.0012 19.0 16.0 0.0026 17.9 13.1 2.4 1 1 1 2 2 2 2 Carbohydrate binding H_lectin PF09458.10 PRP88554.1 - 8.4e-49 163.6 1.4 4.9e-16 58.7 0.0 3.8 4 0 0 4 4 4 3 H-type lectin domain zf-C3HC4_3 PF13920.6 PRP88554.1 - 5e-15 55.1 10.1 9.1e-15 54.3 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP88554.1 - 6.6e-07 29.1 10.5 6.6e-07 29.1 10.5 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PRP88554.1 - 1.5e-05 25.2 10.6 4.3e-05 23.8 10.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PRP88554.1 - 0.00012 21.9 11.7 0.00026 20.9 11.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PRP88554.1 - 0.00019 21.2 11.6 0.00041 20.1 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP88554.1 - 1.6 8.8 12.5 0.48 10.5 8.6 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 PRP88554.1 - 2.4 8.0 7.8 8.8 6.2 1.5 3.1 3 0 0 3 3 3 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 PRP88554.1 - 4 7.7 10.7 10 6.3 10.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LRR_6 PF13516.6 PRP88555.1 - 8.3e-33 109.6 41.0 0.00039 20.3 0.4 12.1 12 0 0 12 12 12 10 Leucine Rich repeat LRR_1 PF00560.33 PRP88555.1 - 1.1e-11 43.6 16.1 1.7 9.5 0.0 10.7 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_4 PF12799.7 PRP88555.1 - 5.5e-11 42.5 32.4 0.0091 16.4 0.6 7.1 3 3 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP88555.1 - 3.9e-05 23.3 35.1 0.00099 18.8 1.8 7.8 2 1 6 8 8 7 5 Leucine rich repeat Macro PF01661.21 PRP88557.1 - 1.2e-12 47.9 0.0 2.2e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Macro domain Macro_2 PF14519.6 PRP88557.1 - 4.9e-12 45.8 0.0 7.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Macro-like domain Transcrip_reg PF01709.20 PRP88557.1 - 0.021 14.3 0.1 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator DUF667 PF05018.13 PRP88558.1 - 2.7e-23 82.7 0.0 7e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF667) NMO PF03060.15 PRP88559.1 - 9.1e-57 192.9 4.9 2e-54 185.2 4.9 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 PRP88559.1 - 9.2e-13 47.9 0.7 2e-10 40.2 0.7 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 PRP88559.1 - 0.02 14.2 0.2 0.045 13.1 0.2 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase G3P_antiterm PF04309.12 PRP88559.1 - 0.043 13.2 2.1 0.25 10.8 0.4 2.8 2 1 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 PRP88559.1 - 0.064 12.7 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF561 PF04481.12 PRP88559.1 - 0.071 12.3 1.3 1.4 8.0 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF561) FMN_dh PF01070.18 PRP88559.1 - 0.31 10.0 2.3 0.53 9.3 2.3 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PPR_3 PF13812.6 PRP88560.1 - 3.7e-17 62.2 0.0 1.5e-06 28.2 0.0 3.3 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 PRP88560.1 - 1.7e-16 60.1 0.1 0.00064 19.9 0.0 5.7 2 1 4 6 6 6 4 PPR repeat family PPR PF01535.20 PRP88560.1 - 5.4e-09 35.7 0.1 0.13 12.6 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 PRP88560.1 - 6.1e-09 35.5 0.0 0.0018 17.7 0.0 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PRP88560.1 - 0.0001 21.9 0.0 9.5 6.0 0.0 5.0 5 1 0 5 5 5 1 PPR repeat Imm51 PF15595.6 PRP88560.1 - 0.025 14.5 0.0 0.095 12.7 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 51 RabGAP-TBC PF00566.18 PRP88560.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Glyco_trans_4_3 PF12000.8 PRP88560.1 - 0.092 12.4 0.0 15 5.2 0.0 2.6 2 1 1 3 3 3 0 Glycosyl transferase family 4 group 4HB_MCP_1 PF12729.7 PRP88560.1 - 0.18 11.3 0.8 5 6.6 0.1 2.9 2 1 2 4 4 4 0 Four helix bundle sensory module for signal transduction DENN PF02141.21 PRP88561.1 - 5.8e-27 94.8 5.3 6.3e-26 91.5 5.3 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PRP88561.1 - 1.3e-05 25.8 1.1 3.4e-05 24.5 0.3 2.1 2 0 0 2 2 2 1 uDENN domain dDENN PF03455.19 PRP88561.1 - 0.0029 17.6 1.7 0.0083 16.1 1.7 1.8 1 0 0 1 1 1 1 dDENN domain Med30 PF11315.8 PRP88561.1 - 0.034 14.3 2.6 0.076 13.2 2.6 1.5 1 0 0 1 1 1 0 Mediator complex subunit 30 Sec5 PF15469.6 PRP88561.1 - 0.036 13.9 0.9 0.14 12.0 0.2 2.1 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF16 PF01519.16 PRP88561.1 - 0.24 11.9 4.9 0.36 11.4 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 PRP88561.1 - 0.97 7.3 3.8 0.57 8.0 1.7 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MAP65_ASE1 PF03999.12 PRP88561.1 - 2.1 6.9 10.6 0.33 9.6 5.8 1.8 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) CASP_C PF08172.12 PRP88561.1 - 5 6.4 7.3 3.9 6.8 2.5 2.2 2 0 0 2 2 2 0 CASP C terminal L51_S25_CI-B8 PF05047.16 PRP88562.1 - 3.9e-06 26.7 0.1 7.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ACBP PF00887.19 PRP88563.1 - 4.2e-25 87.8 0.1 6.7e-25 87.1 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.6 PRP88563.1 - 6.6e-20 70.9 0.2 1.3e-09 38.1 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP88563.1 - 1e-14 54.2 1.0 8.4e-07 29.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 PRP88563.1 - 1.2e-13 51.5 0.2 4.6e-13 49.6 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP88563.1 - 1.8e-12 47.5 0.1 1.6e-10 41.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88563.1 - 1.3e-09 37.4 0.1 0.00029 21.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Laminin_G_3 PF13385.6 PRP88565.1 - 7.8e-38 130.0 1.2 7.8e-21 74.8 0.0 3.1 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily Toxin_R_bind_N PF07953.12 PRP88565.1 - 3.8e-07 30.0 5.5 0.013 15.2 0.2 3.2 2 1 0 2 2 2 2 Clostridium neurotoxin, N-terminal receptor binding DUF4982 PF16355.5 PRP88565.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4982) Lem_TRP PF08262.11 PRP88565.1 - 0.22 11.6 0.3 0.58 10.3 0.3 1.7 1 0 0 1 1 1 0 Leucophaea maderae tachykinin-related peptide SOG2 PF10428.9 PRP88565.1 - 4.9 6.2 11.6 0.25 10.5 6.1 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein Nse4_C PF08743.10 PRP88566.1 - 1.3e-23 83.0 0.0 1.3e-23 83.0 0.0 2.9 4 0 0 4 4 4 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 PRP88566.1 - 0.00017 21.6 0.1 0.00037 20.5 0.1 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE ESSS PF10183.9 PRP88566.1 - 1 9.6 0.0 1 9.6 0.0 3.1 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EF-hand_6 PF13405.6 PRP88567.1 - 6.8e-12 44.3 0.1 4.5e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PRP88567.1 - 6.8e-09 36.1 0.1 0.0011 19.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP88567.1 - 8.6e-08 31.2 0.1 0.003 17.0 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 PRP88567.1 - 2.3e-05 24.6 0.0 0.0076 16.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PRP88567.1 - 0.0025 17.6 0.1 0.099 12.5 0.0 3.0 2 2 2 4 4 4 1 EF-hand domain pair Sec39 PF08314.11 PRP88568.1 - 8.6e-29 100.5 5.4 3.3e-17 62.3 1.2 2.9 1 1 1 2 2 2 2 Secretory pathway protein Sec39 Nbas_N PF15492.6 PRP88568.1 - 6e-18 65.2 0.0 2e-17 63.4 0.0 1.9 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal PTPRCAP PF15713.5 PRP88568.1 - 0.18 12.1 1.1 2.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated CN_hydrolase PF00795.22 PRP88570.1 - 7.4e-46 156.6 0.0 1.1e-45 156.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ICAT PF06384.11 PRP88571.1 - 5.2e-24 84.3 9.7 3.1e-23 81.8 2.1 2.2 2 0 0 2 2 2 2 Beta-catenin-interacting protein ICAT GvpG PF05120.12 PRP88571.1 - 0.027 14.5 6.0 0.08 13.0 0.2 2.4 2 0 0 2 2 2 0 Gas vesicle protein G DUF2408 PF10303.9 PRP88571.1 - 0.11 13.1 10.0 0.18 12.4 1.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) ARA70 PF12489.8 PRP88571.1 - 0.11 12.7 4.8 0.1 12.8 3.4 1.7 2 1 0 2 2 2 0 Nuclear coactivator DUF883 PF05957.13 PRP88571.1 - 2.4 8.8 6.1 5.5 7.7 0.3 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Nucleoporin_C PF03177.14 PRP88572.1 - 3.5e-18 65.7 7.8 3.5e-16 59.1 0.4 3.0 2 1 0 3 3 3 2 Non-repetitive/WGA-negative nucleoporin C-terminal DUF1847 PF08901.11 PRP88572.1 - 0.11 12.2 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1847) Tcp10_C PF07202.13 PRP88574.1 - 3.4e-08 33.7 0.2 3.4e-08 33.7 0.2 2.7 2 1 0 2 2 2 1 T-complex protein 10 C-terminus EzrA PF06160.12 PRP88574.1 - 0.00038 18.8 14.9 0.00042 18.6 9.3 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA HALZ PF02183.18 PRP88574.1 - 0.072 13.3 1.6 0.19 12.0 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Sas10 PF09368.10 PRP88574.1 - 0.21 12.1 8.0 1.7 9.2 7.5 2.9 2 0 0 2 2 2 0 Sas10 C-terminal domain bZIP_1 PF00170.21 PRP88574.1 - 3.6 7.8 15.6 0.29 11.3 1.0 3.6 1 1 1 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 PRP88574.1 - 5.3 7.1 35.7 0.04 14.0 23.0 3.2 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein JIP_LZII PF16471.5 PRP88574.1 - 9.7 6.4 15.9 5.1 7.4 2.7 3.7 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II G_glu_transpept PF01019.21 PRP88575.1 - 6.1e-150 500.4 0.0 8e-150 500.0 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase adh_short PF00106.25 PRP88575.1 - 2.6e-47 160.8 2.6 5.9e-47 159.6 2.6 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP88575.1 - 3.4e-44 151.2 0.2 5.4e-43 147.2 0.2 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase EF-hand_1 PF00036.32 PRP88575.1 - 1e-14 52.9 3.0 2.3e-05 23.6 0.9 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PRP88575.1 - 2.1e-13 49.0 0.6 0.0062 16.4 0.2 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 PRP88575.1 - 2.7e-13 50.1 0.6 7.5e-07 29.5 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP88575.1 - 6.1e-09 35.0 1.8 0.0097 15.4 0.1 3.8 3 0 0 3 3 3 3 EF hand KR PF08659.10 PRP88575.1 - 3.2e-08 33.7 2.3 7.4e-07 29.3 2.3 2.5 1 1 0 1 1 1 1 KR domain EF-hand_8 PF13833.6 PRP88575.1 - 4.3e-07 29.7 2.4 0.013 15.3 0.4 3.8 2 1 1 3 3 3 3 EF-hand domain pair Epimerase PF01370.21 PRP88575.1 - 0.17 11.3 0.3 0.39 10.2 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 PRP88575.1 - 0.19 11.6 2.5 2.5 7.9 0.0 3.0 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cyclin_N PF00134.23 PRP88576.1 - 1.6e-25 89.3 1.9 6.3e-24 84.1 0.4 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP88576.1 - 3.2e-16 59.5 4.7 7.3e-16 58.3 2.3 2.6 2 1 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 PRP88577.1 - 2.7e-38 130.6 2.1 3.5e-35 120.5 0.7 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP88577.1 - 1e-20 74.0 1.3 2.1e-20 73.0 1.3 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain CotH PF08757.11 PRP88578.1 - 4.2e-28 98.8 1.2 3.1e-27 96.0 1.2 2.0 1 1 0 1 1 1 1 CotH kinase protein EGF_2 PF07974.13 PRP88578.1 - 9.2e-05 22.7 31.0 0.0019 18.5 14.7 2.8 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 PRP88578.1 - 0.00011 22.5 22.2 0.0003 21.0 6.8 3.0 2 1 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 PRP88578.1 - 0.00031 20.7 10.7 0.00031 20.7 10.7 2.7 2 0 0 2 2 2 1 Tenascin EGF domain hEGF PF12661.7 PRP88578.1 - 0.0036 17.9 3.9 0.0036 17.9 3.9 3.2 3 0 0 3 3 3 2 Human growth factor-like EGF SAPS PF04499.15 PRP88579.1 - 0.38 9.5 9.2 1.6 7.4 0.1 3.1 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein LMBR1 PF04791.16 PRP88582.1 - 6.1e-101 338.8 23.3 7.4e-101 338.6 23.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Aa_trans PF01490.18 PRP88583.1 - 6.7e-07 28.3 0.0 1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MORN PF02493.20 PRP88586.1 - 1e-22 78.6 51.6 0.00021 21.0 1.2 8.2 8 0 0 8 8 8 7 MORN repeat SCP2 PF02036.17 PRP88586.1 - 8e-05 23.1 1.0 0.00053 20.4 0.0 2.6 3 0 0 3 3 3 1 SCP-2 sterol transfer family GATA PF00320.27 PRP88587.1 - 0.00082 18.9 7.1 0.00086 18.9 5.0 2.2 2 0 0 2 2 2 1 GATA zinc finger NAM-associated PF14303.6 PRP88587.1 - 5.1 7.8 11.7 4.4 8.0 5.7 2.5 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Ras PF00071.22 PRP88588.1 - 6.5e-53 178.7 0.0 1e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88588.1 - 2.9e-20 72.7 0.0 4.6e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Rieske PF00355.26 PRP88588.1 - 3.2e-10 39.8 0.0 7.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 PRP88588.1 - 3.6e-06 27.4 0.0 8.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Arf PF00025.21 PRP88588.1 - 5.3e-05 22.7 0.0 8.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family TIP49 PF06068.13 PRP88589.1 - 2.9e-154 513.5 2.9 4.3e-154 512.9 2.9 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 PRP88589.1 - 2.2e-23 82.2 0.1 1e-22 80.0 0.3 2.1 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 PRP88589.1 - 5e-10 39.9 0.6 1e-06 29.2 0.1 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PRP88589.1 - 2.9e-09 36.9 1.1 3.7e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PRP88589.1 - 3.6e-06 27.5 0.3 1e-05 26.0 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 PRP88589.1 - 5.2e-06 26.5 0.1 0.0021 18.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 PRP88589.1 - 5e-05 23.7 1.5 0.00031 21.1 1.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PRP88589.1 - 6e-05 23.3 0.6 0.26 11.5 0.3 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 PRP88589.1 - 0.00012 21.6 1.0 0.014 14.8 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DnaB_C PF03796.15 PRP88589.1 - 0.00016 21.1 0.3 0.00016 21.1 0.3 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 PRP88589.1 - 0.0019 17.9 0.3 0.44 10.2 0.2 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase PF06745.13 PRP88589.1 - 0.0068 15.8 0.1 0.015 14.6 0.1 1.7 1 0 0 1 1 1 1 KaiC AAA_7 PF12775.7 PRP88589.1 - 0.0093 15.5 0.4 0.035 13.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF2075 PF09848.9 PRP88589.1 - 0.0094 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 PRP88589.1 - 0.012 15.9 0.6 0.03 14.6 0.6 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 PRP88589.1 - 0.014 15.5 1.3 0.079 13.1 0.1 2.6 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 PRP88589.1 - 0.022 14.8 0.1 0.048 13.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 PRP88589.1 - 0.022 14.5 1.7 0.2 11.4 1.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 PRP88589.1 - 0.025 14.0 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 PRP88589.1 - 0.025 14.1 0.3 0.082 12.5 0.3 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 PRP88589.1 - 0.029 13.6 1.7 0.042 13.1 0.6 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 PRP88589.1 - 0.03 14.5 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PRP88589.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 PRP88589.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 PRP88589.1 - 0.08 13.5 0.0 0.33 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 PRP88590.1 - 6.9e-05 23.4 0.2 0.041 14.5 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP88590.1 - 0.0032 18.0 0.1 0.57 10.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FCD PF07729.12 PRP88590.1 - 1.1 9.7 3.7 3.4 8.1 0.1 2.9 2 1 1 3 3 3 0 FCD domain FF PF01846.19 PRP88592.1 - 2.3e-27 94.9 24.7 2e-12 47.1 0.4 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.26 PRP88592.1 - 0.00033 20.7 5.2 0.0048 16.9 0.1 2.9 2 0 0 2 2 2 2 WW domain HTH_38 PF13936.6 PRP88592.1 - 0.028 14.2 0.1 12 5.8 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain RhoGAP-FF1 PF16512.5 PRP88592.1 - 1.1 9.9 10.1 0.23 12.2 0.4 4.1 4 1 0 4 4 4 0 p190-A and -B Rho GAPs FF domain Acetyltransf_16 PF05301.11 PRP88593.1 - 5.3e-53 179.4 0.0 8.2e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Clat_adaptor_s PF01217.20 PRP88593.1 - 1.4e-51 174.2 3.6 2.4e-51 173.4 3.6 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acetyltransf_10 PF13673.7 PRP88593.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PA14 PF07691.12 PRP88594.1 - 1.1e-10 41.5 0.2 7.6e-10 38.8 0.1 2.2 2 0 0 2 2 2 1 PA14 domain HD_3 PF13023.6 PRP88595.1 - 2.6e-47 160.8 0.1 3.8e-47 160.3 0.1 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 PRP88595.1 - 6.9e-11 42.2 0.1 1.1e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Beta_helix PF13229.6 PRP88595.1 - 8.8e-09 35.4 25.7 1.4e-05 25.0 10.4 4.3 2 2 2 4 4 4 3 Right handed beta helix region HD PF01966.22 PRP88595.1 - 0.0017 18.6 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 HD domain P22_portal PF16510.5 PRP88595.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Phage P22-like portal protein PB1 PF00564.24 PRP88596.1 - 3.1e-05 23.8 0.8 0.061 13.3 0.1 3.1 2 1 0 2 2 2 2 PB1 domain UBA PF00627.31 PRP88596.1 - 0.00012 21.9 0.2 0.00025 20.9 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 PRP88596.1 - 0.015 15.3 0.0 0.051 13.6 0.0 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair ZZ PF00569.17 PRP88596.1 - 0.015 15.1 12.2 0.028 14.2 12.2 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-UBR PF02207.20 PRP88596.1 - 0.027 14.6 8.3 0.056 13.6 8.3 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TniQ PF06527.11 PRP88596.1 - 0.17 12.6 1.7 5.7 7.7 0.4 3.0 2 1 0 2 2 2 0 TniQ DUF2039 PF10217.9 PRP88596.1 - 0.34 11.3 6.8 1.5 9.2 7.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) Mito_carr PF00153.27 PRP88597.1 - 2.6e-55 184.3 6.4 2.1e-21 75.7 0.0 5.4 3 2 1 4 4 4 4 Mitochondrial carrier protein SPRY PF00622.28 PRP88597.1 - 1.9e-18 66.7 5.0 7.5e-10 39.0 0.0 4.3 4 1 0 4 4 4 2 SPRY domain C1_1 PF00130.22 PRP88597.1 - 0.013 15.3 8.0 0.027 14.4 8.0 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 PRP88597.1 - 0.019 14.9 6.6 0.044 13.7 6.6 1.6 1 0 0 1 1 1 0 PHD-finger Forkhead PF00250.18 PRP88597.1 - 0.067 13.5 0.2 0.18 12.1 0.2 1.7 1 0 0 1 1 1 0 Forkhead domain Zf_RING PF16744.5 PRP88597.1 - 0.21 11.7 3.1 0.5 10.5 2.4 2.0 2 0 0 2 2 2 0 KIAA1045 RING finger C1_2 PF03107.16 PRP88597.1 - 1 9.7 10.9 0.98 9.8 8.2 2.2 2 0 0 2 2 2 0 C1 domain zf-HC5HC2H PF13771.6 PRP88597.1 - 1.9 8.8 8.4 7.1 7.0 8.4 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain Fe_dep_repr_C PF02742.15 PRP88598.1 - 0.28 11.3 1.9 1.3 9.1 0.2 2.5 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain RNA_pol_Rpb2_7 PF04560.20 PRP88598.1 - 8.3 6.9 14.7 4.2e+02 1.4 14.0 2.4 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 7 DSPc PF00782.20 PRP88599.1 - 4.8e-31 107.3 0.0 1.1e-30 106.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 PRP88599.1 - 1.7e-29 101.4 29.2 4.1e-11 42.5 0.2 5.4 4 1 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 PRP88599.1 - 1.4e-20 73.0 25.4 2.5e-06 27.7 0.5 6.9 4 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP88599.1 - 1.1e-05 25.0 5.8 0.0076 15.8 2.3 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 PRP88599.1 - 0.013 16.0 22.6 3 8.7 0.0 7.9 7 0 0 7 7 7 0 Leucine Rich Repeat Y_phosphatase PF00102.27 PRP88599.1 - 0.083 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LRR_6 PF13516.6 PRP88599.1 - 0.2 11.8 15.1 11 6.4 0.1 6.2 5 0 0 5 5 5 0 Leucine Rich repeat UIM PF02809.20 PRP88600.1 - 0.036 14.0 2.4 0.089 12.7 2.4 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif EamA PF00892.20 PRP88602.1 - 6.8e-07 29.5 15.2 6.8e-07 29.5 15.2 2.6 2 1 0 2 2 2 1 EamA-like transporter family Auto_anti-p27 PF06677.12 PRP88603.1 - 2.1e-29 101.4 8.7 2e-15 56.7 2.1 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2318 PF10080.9 PRP88603.1 - 0.0035 17.5 3.1 0.77 9.9 0.1 2.3 2 0 0 2 2 2 2 Predicted membrane protein (DUF2318) Rep_fac-A_C PF08646.10 PRP88603.1 - 0.008 15.9 3.3 0.97 9.2 0.2 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain zinc-ribbons_6 PF07191.12 PRP88603.1 - 0.029 14.3 6.8 0.29 11.1 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbons RPA_interact_C PF14768.6 PRP88603.1 - 0.056 14.0 2.0 0.58 10.8 0.5 2.3 2 0 0 2 2 2 0 Replication protein A interacting C-terminal DZR PF12773.7 PRP88603.1 - 0.25 11.4 5.1 1.8 8.7 0.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon IBR PF01485.21 PRP88603.1 - 0.3 11.3 4.0 3.8 7.8 0.3 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-piccolo PF05715.13 PRP88603.1 - 1 9.6 7.1 1.2 9.4 0.9 2.5 2 0 0 2 2 2 0 Piccolo Zn-finger Neprosin_AP PF14365.6 PRP88603.1 - 1.6 9.2 4.8 8.2 6.9 0.2 2.9 3 0 0 3 3 3 0 Neprosin activation peptide DUF2464 PF10240.9 PRP88603.1 - 6.2 6.3 8.2 18 4.8 0.0 2.8 2 1 0 2 2 2 0 Multivesicular body subunit 12 Cadherin_3 PF16184.5 PRP88604.1 - 4.8e-19 68.4 31.3 0.00057 19.9 0.0 13.4 16 0 0 16 16 16 5 Cadherin-like VWA PF00092.28 PRP88604.1 - 0.005 17.1 0.3 0.022 15.0 0.1 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Big_9 PF17963.1 PRP88604.1 - 0.011 16.4 1.2 0.011 16.4 1.2 22.8 18 5 1 19 19 19 0 Bacterial Ig domain NHL PF01436.21 PRP88604.1 - 0.7 10.0 5.9 0.38 10.9 0.5 3.5 3 0 0 3 3 3 0 NHL repeat C2 PF00168.30 PRP88606.1 - 1.6e-46 156.8 0.3 3.2e-22 78.8 0.0 3.1 2 0 0 2 2 2 2 C2 domain GRAM PF02893.20 PRP88606.1 - 2.2e-20 72.6 1.4 4.6e-14 52.3 0.0 3.4 3 0 0 3 3 3 2 GRAM domain Membr_traf_MHD PF10540.9 PRP88606.1 - 7e-11 42.5 5.1 1.4e-05 25.3 0.2 3.6 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain FERM_f0 PF16511.5 PRP88606.1 - 0.00048 20.4 0.1 0.004 17.4 0.0 2.5 2 0 0 2 2 2 1 N-terminal or F0 domain of Talin-head FERM CEP76-C2 PF15627.6 PRP88606.1 - 0.031 13.9 0.0 0.33 10.5 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain HCV_NS4a PF01006.20 PRP88607.1 - 0.21 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a ASH PF15780.5 PRP88609.1 - 2.9e-14 53.0 1.6 0.0088 16.2 0.1 6.8 8 0 0 8 8 8 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CBS PF00571.28 PRP88609.1 - 1.9e-08 34.6 0.0 0.0017 18.8 0.0 4.4 4 0 0 4 4 4 2 CBS domain TMEM131_like PF12371.8 PRP88609.1 - 6.5e-06 26.3 1.2 2.8 8.3 0.0 5.0 5 0 0 5 5 5 2 Transmembrane protein 131-like PapD-like PF14874.6 PRP88609.1 - 0.061 13.5 0.3 7.3 6.8 0.1 3.5 4 0 0 4 4 4 0 Flagellar-associated PapD-like Ank_2 PF12796.7 PRP88609.1 - 0.14 12.8 0.0 0.36 11.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) WD40 PF00400.32 PRP88610.1 - 1.1e-79 260.2 82.9 2.9e-05 24.7 0.5 29.2 32 0 0 32 32 30 17 WD domain, G-beta repeat HELP PF03451.14 PRP88610.1 - 3.8e-50 167.6 0.3 2.9e-16 59.1 0.0 3.5 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 PRP88610.1 - 2.1e-40 136.9 0.2 2.2e-05 24.7 0.0 15.1 8 6 7 16 16 15 7 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PRP88610.1 - 3.2e-10 39.4 0.3 0.028 13.2 0.0 5.7 6 1 0 6 6 6 2 Nup133 N terminal like Ion_trans PF00520.31 PRP88610.1 - 5.2e-09 35.7 4.9 8.4e-09 35.0 4.9 1.2 1 0 0 1 1 1 1 Ion transport protein PD40 PF07676.12 PRP88610.1 - 6.7e-09 35.5 1.5 6.3 6.9 0.0 9.0 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 PRP88610.1 - 1.5e-08 33.6 0.3 0.0032 16.0 0.0 5.9 6 2 0 6 6 6 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 PRP88610.1 - 1.2e-07 31.1 0.8 0.067 12.2 0.0 5.7 5 2 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PRP88610.1 - 0.00028 20.3 6.4 32 3.7 0.0 7.5 6 2 0 7 7 7 0 WD40-like domain PSII_BNR PF14870.6 PRP88610.1 - 0.014 14.7 1.3 0.12 11.6 0.0 2.9 3 0 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 Frtz PF11768.8 PRP88610.1 - 0.015 13.7 0.0 0.42 8.9 0.0 2.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 PRP88610.1 - 0.015 13.9 0.1 2.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Nucleoporin Nup120/160 ThiP_synth PF10120.9 PRP88610.1 - 0.055 13.1 0.0 6.6 6.3 0.0 3.2 3 0 0 3 3 3 0 Thiamine-phosphate synthase DUF1295 PF06966.12 PRP88610.1 - 0.42 10.1 1.9 0.96 8.9 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF5582 PF17819.1 PRP88611.1 - 0.016 15.6 0.1 0.023 15.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5582) eIF2A PF08662.11 PRP88612.1 - 3.9e-71 238.9 0.1 3.1e-69 232.7 0.0 3.2 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A LRR_8 PF13855.6 PRP88612.1 - 5.3e-34 115.8 36.2 2.8e-10 39.8 2.6 7.0 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PRP88612.1 - 9e-29 99.1 38.2 1.5e-06 28.4 0.5 8.5 5 1 4 9 9 9 8 Leucine Rich repeats (2 copies) RasGEF PF00617.19 PRP88612.1 - 7.7e-21 75.1 0.0 3.2e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 PRP88612.1 - 6.2e-13 48.9 0.6 1.8e-12 47.4 0.6 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif LRR_9 PF14580.6 PRP88612.1 - 6.2e-10 38.8 11.2 9.2e-07 28.5 0.4 4.6 2 2 3 5 5 5 3 Leucine-rich repeat Drf_FH3 PF06367.16 PRP88612.1 - 2.5e-07 30.5 0.4 6.4e-07 29.2 0.4 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain FERM_f0 PF16511.5 PRP88612.1 - 9.9e-07 29.0 0.0 0.18 12.1 0.0 3.6 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM Drf_GBD PF06371.13 PRP88612.1 - 7.2e-05 22.4 0.1 0.00017 21.2 0.1 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF4859 PF16151.5 PRP88612.1 - 0.002 18.0 0.6 0.0068 16.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4859) TFIIIC_delta PF12657.7 PRP88612.1 - 0.024 14.6 0.4 1.2 9.0 0.4 2.7 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term LRR_1 PF00560.33 PRP88612.1 - 0.068 13.7 42.5 5.8 7.9 0.1 11.1 11 0 0 11 11 10 0 Leucine Rich Repeat ORC6 PF05460.13 PRP88613.1 - 3 7.0 11.6 4.2 6.6 11.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TPPK_C PF12555.8 PRP88615.1 - 0.001 19.1 0.4 0.071 13.2 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphokinase C terminal OppC_N PF12911.7 PRP88615.1 - 0.062 13.3 4.3 1.2 9.2 0.1 3.4 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C APG17 PF04108.12 PRP88616.1 - 1.8e-15 57.0 16.9 1.8e-15 57.0 16.9 7.1 2 2 2 4 4 4 2 Autophagy protein Apg17 ubiquitin PF00240.23 PRP88616.1 - 0.00012 21.8 7.0 0.00078 19.2 0.0 4.0 3 0 0 3 3 3 1 Ubiquitin family AAA_13 PF13166.6 PRP88616.1 - 0.001 17.8 22.8 0.001 17.8 22.8 6.4 2 2 3 6 6 6 3 AAA domain DUF3450 PF11932.8 PRP88616.1 - 0.0034 16.7 12.7 0.0034 16.7 12.7 8.9 3 2 6 9 9 9 3 Protein of unknown function (DUF3450) Rad60-SLD PF11976.8 PRP88616.1 - 0.0063 16.3 0.1 0.26 11.1 0.0 2.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF423 PF04241.15 PRP88617.1 - 3e-23 81.8 3.1 5.2e-23 81.0 3.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) VWA_N PF08399.11 PRP88618.1 - 0.038 14.5 0.0 0.046 14.2 0.0 1.2 1 0 0 1 1 1 0 VWA N-terminal Cellulase PF00150.18 PRP88619.1 - 2e-18 66.8 3.3 2.9e-18 66.3 3.3 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.18 PRP88619.1 - 4.1e-08 33.2 13.6 4.1e-08 33.2 13.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4434 PF14488.6 PRP88619.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) DUF11 PF01345.18 PRP88620.1 - 0.046 14.0 0.6 0.081 13.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF11 HIG_1_N PF04588.13 PRP88621.1 - 1.9e-15 56.8 0.6 2.3e-15 56.6 0.6 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region NVEALA PF14055.6 PRP88621.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 NVEALA protein BRE1 PF08647.11 PRP88622.1 - 5.1e-11 42.5 13.4 5.1e-11 42.5 13.4 12.4 4 3 9 13 13 13 4 BRE1 E3 ubiquitin ligase VEGF_C PF14554.6 PRP88622.1 - 0.0015 18.5 0.9 2.8 8.1 0.1 2.8 2 0 0 2 2 2 2 VEGF heparin-binding domain Polysacc_deac_1 PF01522.21 PRP88622.1 - 2.5 8.0 8.0 3.1 7.7 0.3 4.1 2 1 1 4 4 4 0 Polysaccharide deacetylase MmgE_PrpD PF03972.14 PRP88623.1 - 2.6e-121 405.2 0.0 3.3e-121 404.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Citrate_synt PF00285.21 PRP88624.1 - 2.2e-95 319.8 0.0 2.9e-95 319.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Sod_Ni PF09055.11 PRP88624.1 - 0.0072 16.9 0.2 0.013 16.0 0.2 1.4 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase PEP_mutase PF13714.6 PRP88625.1 - 3.4e-52 177.3 0.5 4e-52 177.1 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 PRP88625.1 - 1.1e-12 47.3 0.1 1.5e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 PRP88625.1 - 0.042 13.2 0.0 0.13 11.6 0.0 1.7 1 1 1 2 2 2 0 Ketopantoate hydroxymethyltransferase RRM_1 PF00076.22 PRP88626.1 - 2.5e-81 267.5 4.2 1.6e-19 69.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclin_N PF00134.23 PRP88626.1 - 7.7e-30 103.2 0.4 1.9e-29 101.9 0.4 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain PABP PF00658.18 PRP88626.1 - 2.1e-21 75.9 0.3 6.2e-21 74.4 0.3 1.9 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Cyclin_C PF02984.19 PRP88626.1 - 6.3e-16 58.5 0.0 1.8e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Nup35_RRM_2 PF14605.6 PRP88626.1 - 2.2e-06 27.6 0.3 0.11 12.5 0.0 4.2 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PRP88626.1 - 5.8e-06 26.3 0.1 8.2 6.6 0.0 5.2 4 1 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 PRP88626.1 - 1.1e-05 25.2 0.0 0.075 12.9 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 PRP88626.1 - 0.00015 21.7 3.0 2 8.5 0.1 4.4 4 0 0 4 4 4 1 RNA binding motif SET_assoc PF11767.8 PRP88626.1 - 0.00022 20.8 0.6 11 5.7 0.0 4.3 4 0 0 4 4 4 2 Histone lysine methyltransferase SET associated WD-3 PF09765.9 PRP88627.1 - 2.8e-74 250.0 1.4 3.2e-74 249.8 1.4 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 PRP88627.1 - 4.1e-06 26.9 0.6 7.8e-06 26.0 0.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain UQ_con PF00179.26 PRP88627.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Cep57_MT_bd PF06657.13 PRP88627.1 - 0.032 14.7 0.6 9.5 6.8 0.3 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 RWD PF05773.22 PRP88627.1 - 0.048 13.9 0.2 0.084 13.2 0.2 1.6 1 0 0 1 1 1 0 RWD domain LSM PF01423.22 PRP88628.1 - 3.5e-20 71.5 0.1 4.6e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Aminotran_1_2 PF00155.21 PRP88629.1 - 1.9e-77 260.9 0.0 2.5e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PRP88629.1 - 6.6e-07 28.6 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PRP88629.1 - 4.7e-06 25.4 0.0 7.3e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 PRP88629.1 - 0.08 12.2 0.3 0.25 10.6 0.0 1.8 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Response_reg PF00072.24 PRP88630.1 - 2.2e-20 72.9 0.7 3.1e-19 69.2 0.2 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 PRP88630.1 - 3.2e-18 66.3 0.1 6.8e-18 65.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PRP88630.1 - 4.3e-15 55.5 0.1 9e-14 51.3 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain MASE3 PF17159.4 PRP88630.1 - 2e-12 47.2 12.9 3.5e-12 46.5 12.9 1.4 1 0 0 1 1 1 1 Membrane-associated sensor domain PAS PF00989.25 PRP88630.1 - 0.029 14.4 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 PAS fold CAP_N PF01213.19 PRP88631.1 - 2.6e-81 273.6 1.0 3.7e-81 273.0 1.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 PRP88631.1 - 1.2e-58 197.1 10.1 2e-58 196.5 10.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 PRP88631.1 - 0.00038 20.2 4.1 0.00076 19.2 4.1 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Bacillus_HBL PF05791.11 PRP88631.1 - 0.065 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PAR1 PF06521.11 PRP88631.1 - 0.14 11.8 3.1 1.5 8.4 0.3 3.2 2 1 1 3 3 3 0 PAR1 protein Matrilin_ccoil PF10393.9 PRP88631.1 - 0.15 12.0 0.2 0.15 12.0 0.2 1.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin GCS PF03074.16 PRP88633.1 - 0.15 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase RVT_1 PF00078.27 PRP88634.1 - 2.5e-21 76.2 0.0 2.7e-19 69.6 0.0 3.1 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3902 PF13042.6 PRP88634.1 - 0.00091 18.8 0.0 1.8 8.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3902) AAA_8 PF12780.7 PRP88636.1 - 0.056 12.8 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Baculo_8kDa PF06096.11 PRP88636.1 - 0.091 12.9 0.3 0.23 11.6 0.3 1.6 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein GPS PF01825.21 PRP88639.1 - 6.4e-10 39.4 4.3 2.7e-09 37.4 4.3 2.2 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif TMEM154 PF15102.6 PRP88639.1 - 9.8e-05 22.3 0.2 9.8e-05 22.3 0.2 3.5 2 1 0 2 2 1 1 TMEM154 protein family DUF3377 PF11857.8 PRP88639.1 - 0.0035 17.2 0.1 0.007 16.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DAG1 PF05454.11 PRP88639.1 - 0.016 14.6 0.1 0.016 14.6 0.1 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) CD34_antigen PF06365.12 PRP88639.1 - 0.027 14.1 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF5305 PF17231.2 PRP88639.1 - 0.029 13.8 0.1 0.029 13.8 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 PRP88639.1 - 0.03 15.2 0.0 0.077 13.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 PRP88639.1 - 0.039 13.7 1.0 0.084 12.6 1.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Orf78 PF06024.12 PRP88639.1 - 0.062 13.6 0.4 0.17 12.2 0.4 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF4690 PF15756.5 PRP88639.1 - 0.068 13.8 0.0 0.068 13.8 0.0 3.1 2 1 1 3 3 2 0 Small Novel Rich in Cartilage DUF1180 PF06679.12 PRP88639.1 - 0.12 12.8 0.0 0.12 12.8 0.0 3.2 3 1 0 3 3 2 0 Protein of unknown function (DUF1180) SKG6 PF08693.10 PRP88639.1 - 0.19 11.2 5.5 0.56 9.7 5.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Apt1 PF10351.9 PRP88639.1 - 0.24 10.2 6.5 0.34 9.7 6.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RIFIN PF02009.16 PRP88639.1 - 0.24 11.3 4.9 0.88 9.4 0.0 2.2 2 0 0 2 2 2 0 Rifin Stevor PF17410.2 PRP88639.1 - 0.43 10.1 0.0 0.43 10.1 0.0 2.2 2 0 0 2 2 1 0 Subtelomeric Variable Open Reading frame HAD_2 PF13419.6 PRP88640.1 - 5e-05 23.4 3.9 0.00099 19.2 0.1 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PRP88640.1 - 0.033 14.3 0.0 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PRP88640.1 - 0.052 13.8 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DnaJ PF00226.31 PRP88641.1 - 5.5e-21 74.5 1.1 2.7e-20 72.2 1.1 2.3 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-binding PF00249.31 PRP88641.1 - 1.2e-16 60.6 4.5 1.6e-07 31.4 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP88641.1 - 8.3e-09 35.6 5.5 3.7e-05 23.9 0.1 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain NdhM PF10664.9 PRP88641.1 - 2.1 8.6 4.8 0.53 10.6 0.2 2.4 3 0 0 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M Sin3a_C PF16879.5 PRP88642.1 - 1.2e-44 153.2 3.5 1.2e-44 153.2 3.5 3.5 4 1 0 4 4 4 2 C-terminal domain of Sin3a protein PAH PF02671.21 PRP88642.1 - 1.7e-44 149.7 9.6 6e-18 64.7 2.9 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 PRP88642.1 - 8.3e-32 109.2 4.4 2.3e-30 104.5 0.0 3.4 2 1 1 3 3 3 2 Sin3 family co-repressor NUC173 PF08161.12 PRP88643.1 - 1.8e-53 181.3 3.5 2.2e-52 177.7 0.1 3.5 4 0 0 4 4 4 1 NUC173 domain MOR2-PAG1_C PF14225.6 PRP88643.1 - 0.00096 19.1 0.2 0.95 9.3 0.0 3.7 4 0 0 4 4 4 2 Cell morphogenesis C-terminal MMS19_C PF12460.8 PRP88643.1 - 0.028 13.5 19.0 0.39 9.8 0.3 4.4 3 1 2 5 5 5 0 RNAPII transcription regulator C-terminal HEAT PF02985.22 PRP88643.1 - 0.084 13.2 0.0 78 3.9 0.0 4.6 5 1 1 6 6 6 0 HEAT repeat DUF3384 PF11864.8 PRP88643.1 - 0.34 9.7 9.3 0.1 11.5 0.1 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3384) CENP-B_dimeris PF09026.10 PRP88643.1 - 1.4 9.3 8.1 1 9.8 0.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CRAL_TRIO PF00650.20 PRP88645.1 - 4.1e-27 94.9 0.0 6.2e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP88645.1 - 4.4e-05 23.6 0.2 0.00011 22.3 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain GOLD_2 PF13897.6 PRP88645.1 - 0.00017 22.1 9.7 0.0059 17.1 0.1 3.1 2 1 1 3 3 3 2 Golgi-dynamics membrane-trafficking EMP24_GP25L PF01105.24 PRP88645.1 - 0.0025 17.8 2.4 0.0026 17.7 0.6 1.8 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD CRAL_TRIO_2 PF13716.6 PRP88645.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Med19 PF10278.9 PRP88645.1 - 0.46 10.4 17.2 0.78 9.6 17.2 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF3464 PF11947.8 PRP88645.1 - 9.7 5.9 6.7 78 3.0 6.8 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 GYF PF02213.16 PRP88647.1 - 3.7e-16 58.5 0.3 8e-16 57.4 0.3 1.6 1 0 0 1 1 1 1 GYF domain COPI_C PF06957.11 PRP88647.1 - 1.2e-07 30.9 0.1 2.6e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus EF-hand_4 PF12763.7 PRP88647.1 - 2.6e-07 30.5 0.0 6.7e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Sel1 PF08238.12 PRP88647.1 - 1.1e-05 25.9 0.1 0.035 14.8 0.1 3.2 3 0 0 3 3 3 2 Sel1 repeat EF-hand_7 PF13499.6 PRP88647.1 - 0.054 14.0 0.5 2.7 8.5 0.9 3.1 2 1 0 2 2 2 0 EF-hand domain pair DZR PF12773.7 PRP88647.1 - 0.25 11.4 1.5 0.57 10.3 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon Rep_fac_C PF08542.11 PRP88648.1 - 2.4e-19 69.5 0.1 6.3e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 PRP88648.1 - 1.2e-16 61.3 0.1 5.7e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PRP88648.1 - 5.9e-13 48.9 0.0 6.9e-10 38.9 0.0 2.9 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 PRP88648.1 - 4.1e-07 30.1 0.1 1.9e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 PRP88648.1 - 1.5e-05 25.4 0.0 2.3e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 PRP88648.1 - 6.3e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PRP88648.1 - 8e-05 22.5 0.1 0.0004 20.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PRP88648.1 - 0.00017 21.9 0.8 0.46 10.8 0.1 2.8 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 PRP88648.1 - 0.00021 21.3 0.1 0.0012 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 PRP88648.1 - 0.00022 20.5 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 PRP88648.1 - 0.00023 20.7 0.0 0.00046 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 PRP88648.1 - 0.00025 20.8 0.0 0.00062 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PRP88648.1 - 0.00029 20.6 0.0 0.00074 19.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 PRP88648.1 - 0.00078 19.3 0.1 0.0034 17.3 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 PRP88648.1 - 0.0012 18.6 0.2 0.03 14.1 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_assoc_2 PF16193.5 PRP88648.1 - 0.0018 18.6 0.0 0.0061 16.9 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_5 PF07728.14 PRP88648.1 - 0.004 17.2 0.0 0.011 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 PRP88648.1 - 0.0066 16.8 0.7 0.045 14.1 0.7 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 PRP88648.1 - 0.007 16.4 0.0 0.03 14.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit TniB PF05621.11 PRP88648.1 - 0.0073 15.7 0.8 0.42 10.0 0.0 2.8 2 1 1 3 3 3 1 Bacterial TniB protein AAA_18 PF13238.6 PRP88648.1 - 0.0095 16.5 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain DNA_pol3_delta PF06144.13 PRP88648.1 - 0.01 15.6 0.1 0.032 14.0 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit ATPase_2 PF01637.18 PRP88648.1 - 0.011 15.7 0.8 0.029 14.3 0.0 2.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 PRP88648.1 - 0.033 13.9 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 PRP88648.1 - 0.064 13.7 0.2 0.1 13.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PRP88648.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 PRP88648.1 - 0.2 11.2 0.7 3.6 7.1 0.1 2.8 2 1 1 3 3 3 0 AAA domain CAP59_mtransfer PF11735.8 PRP88649.1 - 8.3e-42 143.5 0.0 1.1e-41 143.1 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 TPR_1 PF00515.28 PRP88650.1 - 6.9e-05 22.5 3.9 0.044 13.6 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP88650.1 - 0.00018 21.6 0.9 0.035 14.5 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP88650.1 - 0.0022 17.9 3.4 5.3 7.4 0.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PRP88650.1 - 0.0042 16.7 1.6 0.74 9.6 0.1 2.5 2 0 0 2 2 2 2 TPR repeat zf-MYND PF01753.18 PRP88650.1 - 0.037 14.1 13.5 0.11 12.6 13.5 1.8 1 1 0 1 1 1 0 MYND finger Mut7-C PF01927.16 PRP88650.1 - 0.094 12.8 6.7 0.33 11.1 5.6 2.3 2 1 0 2 2 2 0 Mut7-C RNAse domain TPR_19 PF14559.6 PRP88650.1 - 0.62 10.6 3.4 0.78 10.3 1.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP88650.1 - 1.7 9.0 5.0 90 3.7 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat 2TM PF13239.6 PRP88651.1 - 1.8 8.9 60.1 0.12 12.7 6.1 4.1 1 1 3 4 4 4 0 2TM domain 7TMR-DISM_7TM PF07695.11 PRP88651.1 - 9.4 6.1 46.1 4.3 7.2 21.1 2.7 1 1 2 3 3 3 0 7TM diverse intracellular signalling GST_N_4 PF17172.4 PRP88652.1 - 1.5e-18 67.4 0.0 2.8e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 PRP88652.1 - 2.8e-05 23.8 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 PRP88652.1 - 0.00088 19.6 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 PRP88652.1 - 0.0044 17.0 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_20 PF00728.22 PRP88653.1 - 1.6e-105 353.4 0.1 2.3e-105 352.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 PRP88653.1 - 9.3e-20 71.7 0.2 2.8e-19 70.1 0.1 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 PRP88653.1 - 7.5e-08 33.2 0.0 1.5e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ArfGap PF01412.18 PRP88654.1 - 8.9e-38 129.0 4.0 6e-37 126.3 0.0 3.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Homeodomain PF00046.29 PRP88654.1 - 3.2e-16 58.9 2.5 3.2e-16 58.9 2.5 2.7 3 0 0 3 3 3 1 Homeodomain PH PF00169.29 PRP88654.1 - 0.00081 19.9 0.0 0.0032 17.9 0.0 2.1 1 0 0 1 1 1 1 PH domain Gln_amidase PF15644.6 PRP88654.1 - 0.021 15.8 2.4 4 8.5 0.2 3.6 2 1 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase DUF5352 PF17303.2 PRP88654.1 - 1.8 8.4 6.6 9.1 6.1 0.8 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5352) U79_P34 PF03064.16 PRP88654.1 - 4.2 6.7 24.4 0.029 13.7 10.2 3.5 3 0 0 3 3 3 0 HSV U79 / HCMV P34 Pkinase PF00069.25 PRP88655.1 - 9.7e-82 274.3 0.0 1.2e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88655.1 - 3.2e-39 134.8 0.0 4.5e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP88655.1 - 3.5e-08 33.1 0.1 6.1e-05 22.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PRP88655.1 - 6.4e-06 25.2 0.1 8.7e-05 21.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PRP88655.1 - 0.00011 21.6 0.6 0.00017 21.0 0.2 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP88655.1 - 0.012 15.2 4.4 0.13 11.9 4.4 2.0 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 PRP88655.1 - 0.085 12.8 0.1 0.28 11.1 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 PRP88657.1 - 1e-42 145.5 0.1 1.2e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88657.1 - 2.6e-19 69.6 0.0 4.1e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP88657.1 - 0.00029 20.3 0.0 0.00057 19.4 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP88657.1 - 0.067 13.3 0.1 0.093 12.8 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 PRP88657.1 - 0.17 11.6 0.5 4.9 6.9 0.2 2.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1992 PF09350.10 PRP88658.1 - 1.6e-05 25.0 0.0 5.5e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Fib_alpha PF08702.10 PRP88658.1 - 0.45 10.7 9.5 0.93 9.7 0.7 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family PhdYeFM_antitox PF02604.19 PRP88660.1 - 0.096 12.5 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Ferrochelatase PF00762.19 PRP88661.1 - 5.8e-105 350.9 0.0 6.9e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase His_Phos_1 PF00300.22 PRP88661.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) RhoGEF PF00621.20 PRP88662.1 - 1.2e-43 149.5 1.3 1.2e-43 149.5 1.3 2.4 2 0 0 2 2 2 1 RhoGEF domain XAP5 PF04921.14 PRP88662.1 - 1.5e-36 126.5 19.1 1.5e-36 126.5 19.1 3.6 3 1 0 3 3 3 1 XAP5, circadian clock regulator CH PF00307.31 PRP88662.1 - 3.6e-07 30.3 0.1 2.5e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain Glyco_hydro_20 PF00728.22 PRP88663.1 - 1.7e-132 442.1 0.5 1.2e-99 334.1 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 PRP88663.1 - 8.6e-14 52.4 0.0 1.6e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 PRP88663.1 - 4.9e-09 37.0 0.0 8.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Homeodomain PF00046.29 PRP88664.1 - 1.5e-16 60.0 5.7 3.8e-15 55.5 2.1 2.4 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 PRP88664.1 - 0.00035 20.4 0.0 0.00092 19.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 PRP88664.1 - 0.084 12.3 0.2 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Epimerase PF01370.21 PRP88665.1 - 1.6e-25 90.0 0.2 2.8e-25 89.2 0.2 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP88665.1 - 3.8e-13 49.6 0.3 5.7e-13 49.0 0.3 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PRP88665.1 - 7.9e-13 48.1 0.1 1.4e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 PRP88665.1 - 7.8e-12 44.8 0.1 1.3e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PRP88665.1 - 9.4e-10 38.7 0.1 1.7e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ACI44 PF15270.6 PRP88665.1 - 1.1 9.5 7.2 0.075 13.2 0.7 2.5 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor DAGAT PF03982.13 PRP88666.1 - 2.2e-103 345.2 0.2 2.6e-103 345.0 0.2 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase NAGLU PF05089.12 PRP88666.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain TPT PF03151.16 PRP88667.1 - 1.3e-21 77.3 24.8 1.6e-21 76.9 24.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PRP88667.1 - 4.9e-05 22.7 24.1 6.7e-05 22.2 24.1 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PRP88667.1 - 0.96 9.6 31.0 2.9 8.1 9.1 2.3 2 0 0 2 2 2 0 EamA-like transporter family 2OG-Fe_Oxy_2 PF10014.9 PRP88668.1 - 2e-29 102.7 0.1 9.4e-28 97.3 0.1 2.1 1 1 0 1 1 1 1 2OG-Fe dioxygenase AMPK1_CBM PF16561.5 PRP88669.1 - 2e-29 101.6 2.6 6.2e-14 52.0 0.3 2.9 2 1 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase Pur_ac_phosph_N PF16656.5 PRP88669.1 - 3.4e-06 27.5 7.9 0.0073 16.9 0.1 3.6 3 1 0 3 3 3 2 Purple acid Phosphatase, N-terminal domain CBM_48 PF02922.18 PRP88669.1 - 6.5e-06 26.4 1.2 0.1 13.0 0.1 2.8 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) PhoD_N PF16655.5 PRP88669.1 - 2.9e-05 24.5 0.0 0.61 10.7 0.0 3.6 2 0 0 2 2 2 2 PhoD-like phosphatase, N-terminal domain AAA_15 PF13175.6 PRP88669.1 - 0.001 18.9 20.2 0.001 18.9 20.2 2.9 1 1 1 2 2 2 1 AAA ATPase domain ATG16 PF08614.11 PRP88669.1 - 0.0035 17.6 16.0 0.0035 17.6 16.0 6.3 3 2 4 7 7 7 3 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 PRP88669.1 - 0.0078 15.4 10.3 0.0078 15.4 10.3 3.2 3 0 0 3 3 2 1 HAP1 N-terminal conserved region HOOK PF05622.12 PRP88669.1 - 0.011 14.0 93.7 0.0037 15.5 9.3 3.7 3 1 1 4 4 4 0 HOOK protein DUF5339 PF17274.2 PRP88669.1 - 0.02 15.7 4.9 0.02 15.7 4.9 6.6 2 2 3 6 6 3 0 Family of unknown function (DUF5339) CENP-F_leu_zip PF10473.9 PRP88669.1 - 2.5 8.1 103.0 0.43 10.6 2.4 5.9 3 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 PRP88669.1 - 5.5 5.8 98.4 0.028 13.3 12.7 4.6 3 1 0 4 4 4 0 Spc7 kinetochore protein KH_1 PF00013.29 PRP88670.1 - 7.8e-08 32.0 0.0 0.00093 19.0 0.0 2.5 2 0 0 2 2 2 2 KH domain GDA1_CD39 PF01150.17 PRP88671.1 - 2e-38 132.2 0.1 2.8e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PSI PF01437.25 PRP88671.1 - 1.6 9.3 11.7 3.6 8.2 11.7 1.6 1 0 0 1 1 1 0 Plexin repeat AAA PF00004.29 PRP88672.1 - 1.4e-38 132.3 0.0 2.6e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PRP88672.1 - 3.2e-07 30.2 0.0 1.2e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PRP88672.1 - 4.7e-07 30.3 0.4 1.4e-05 25.5 0.4 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_3 PF17862.1 PRP88672.1 - 2.3e-06 27.3 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain DUF815 PF05673.13 PRP88672.1 - 8.7e-06 25.1 0.0 1.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 PRP88672.1 - 1.2e-05 25.4 0.1 0.00011 22.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 PRP88672.1 - 2e-05 24.4 0.0 5.3e-05 23.0 0.0 1.7 1 1 1 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 PRP88672.1 - 7.7e-05 23.0 0.1 0.0078 16.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 PRP88672.1 - 0.00011 22.7 0.0 0.00019 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PRP88672.1 - 0.00029 21.3 0.0 0.00058 20.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_24 PF13479.6 PRP88672.1 - 0.0011 18.8 0.0 0.0054 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 PRP88672.1 - 0.0014 18.3 0.1 0.025 14.3 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 PRP88672.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PRP88672.1 - 0.0022 17.5 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 PRP88672.1 - 0.0037 16.5 0.0 0.0078 15.4 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 PRP88672.1 - 0.0046 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ATPase_2 PF01637.18 PRP88672.1 - 0.0064 16.4 0.0 0.047 13.6 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 PRP88672.1 - 0.0072 16.5 0.0 0.023 14.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PRP88672.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 PRP88672.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 PRP88672.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PRP88672.1 - 0.017 14.5 0.2 0.054 12.9 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 PRP88672.1 - 0.028 14.4 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 PRP88672.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PRP88672.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PRP88672.1 - 0.037 14.0 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Bac_DnaA PF00308.18 PRP88672.1 - 0.039 13.8 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_17 PF13207.6 PRP88672.1 - 0.05 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 PRP88672.1 - 0.057 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.6 PRP88672.1 - 0.071 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 PRP88672.1 - 0.079 12.3 0.3 5.5 6.3 0.1 2.2 1 1 1 2 2 2 0 KaiC Cytidylate_kin PF02224.18 PRP88672.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase NB-ARC PF00931.22 PRP88672.1 - 0.094 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_3 PF07726.11 PRP88672.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 PRP88672.1 - 0.13 12.0 0.6 3.9 7.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 PRP88672.1 - 0.16 11.5 0.3 0.52 9.9 0.1 1.9 2 0 0 2 2 1 0 AAA domain MCM PF00493.23 PRP88672.1 - 0.19 10.8 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain SKI PF01202.22 PRP88672.1 - 0.2 11.8 0.0 0.63 10.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate kinase ADH_zinc_N PF00107.26 PRP88675.1 - 8.5e-08 32.2 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP88675.1 - 3.6e-05 23.6 0.0 0.00026 20.8 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PRP88675.1 - 0.0037 18.3 0.0 0.0071 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FKBP_C PF00254.28 PRP88676.1 - 1.3e-33 115.2 0.0 3e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Rpr2 PF04032.16 PRP88676.1 - 6.1e-13 48.9 0.1 6.1e-13 48.9 0.1 3.2 3 0 0 3 3 3 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain LRR_6 PF13516.6 PRP88677.1 - 3.4e-18 64.1 28.6 0.0013 18.6 0.0 12.2 13 0 0 13 13 13 4 Leucine Rich repeat LRR_4 PF12799.7 PRP88677.1 - 2.7e-09 37.1 32.8 0.038 14.4 3.7 7.9 3 2 6 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP88677.1 - 0.0023 18.2 32.5 1.2 10.0 0.1 10.6 11 1 0 11 11 11 2 Leucine Rich Repeat Preseq_ALAS PF09029.10 PRP88677.1 - 0.069 13.6 9.4 0.52 10.8 0.2 4.5 4 2 2 6 6 6 0 5-aminolevulinate synthase presequence Peptidase_S41 PF03572.18 PRP88678.1 - 1.1e-05 25.1 0.0 2.6e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 DUF4460 PF14687.6 PRP88678.1 - 0.018 15.1 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) RGS PF00615.19 PRP88679.1 - 6.4e-16 58.7 0.4 2.1e-15 57.0 0.4 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain LIM PF00412.22 PRP88679.1 - 1.2e-15 57.5 12.7 5.8e-08 32.8 2.3 3.0 3 0 0 3 3 3 2 LIM domain PTEN_C2 PF10409.9 PRP88679.1 - 2.1e-07 30.8 0.4 6.4e-07 29.2 0.1 2.1 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein Nitrophorin PF02087.15 PRP88679.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Nitrophorin Zn-ribbon_8 PF09723.10 PRP88679.1 - 0.036 14.2 1.9 0.18 11.9 1.9 2.3 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 PRP88679.1 - 0.25 10.9 3.7 0.86 9.2 0.4 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding cNMP_binding PF00027.29 PRP88680.1 - 4.4e-15 55.5 0.0 4.7e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DIM1 PF02966.16 PRP88681.1 - 0.00042 20.1 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 PRP88681.1 - 0.043 13.8 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin P3A PF08727.11 PRP88681.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Poliovirus 3A protein like NMT1 PF09084.11 PRP88684.1 - 4.1e-11 43.2 0.0 5.4e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 PRP88684.1 - 1.7e-08 34.4 0.0 2.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 PRP88684.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 PRP88684.1 - 0.007 15.8 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.20 PRP88684.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.4 1 1 0 1 1 1 0 LysR substrate binding domain NAPRTase_N PF17767.1 PRP88684.1 - 0.028 14.8 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SBP_bac_11 PF13531.6 PRP88684.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.3 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein HIT PF01230.23 PRP88685.1 - 2.1e-22 79.7 0.0 3.2e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PRP88685.1 - 2e-12 47.6 0.0 2.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DCX PF03607.17 PRP88686.1 - 2.4e-54 181.3 0.2 5.1e-17 61.7 0.0 3.3 3 0 0 3 3 3 3 Doublecortin Ig_5 PF16681.5 PRP88686.1 - 0.14 12.6 0.1 32 5.0 0.0 2.5 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain BRE1 PF08647.11 PRP88687.1 - 0.0098 16.0 4.0 0.0098 16.0 4.0 8.5 3 3 4 8 8 8 3 BRE1 E3 ubiquitin ligase DUF5333 PF17267.2 PRP88687.1 - 0.02 15.1 3.2 0.074 13.2 0.0 3.4 1 1 2 3 3 3 0 Family of unknown function (DUF5333) PH PF00169.29 PRP88688.1 - 1.8e-16 60.6 0.0 4e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PRP88688.1 - 8.5e-07 29.4 2.9 1.5e-06 28.5 1.4 2.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 PRP88688.1 - 1.5e-06 28.3 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PRP88688.1 - 2.7e-05 24.4 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PRP88688.1 - 0.017 15.5 0.1 0.17 12.2 0.1 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain RCC1 PF00415.18 PRP88690.1 - 2e-51 172.4 7.2 1.6e-13 51.0 0.0 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 PRP88690.1 - 1.3e-22 80.1 0.0 6.8e-13 48.8 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 PRP88690.1 - 3.9e-21 74.3 13.2 4e-06 26.5 0.2 5.7 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 PRP88690.1 - 1.8e-09 38.0 0.1 4.4e-09 36.8 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP88690.1 - 2.6e-09 37.4 0.2 0.00018 22.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP88690.1 - 7e-07 29.4 0.0 0.084 13.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PRP88690.1 - 2.9e-05 24.3 0.2 0.16 12.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88690.1 - 0.00021 21.5 0.0 2.3 9.0 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Cupin_8 PF13621.6 PRP88691.1 - 7.7e-46 156.9 0.0 2.1e-45 155.4 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain Methyltransf_16 PF10294.9 PRP88691.1 - 4.7e-26 91.6 0.0 1e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Homeodomain PF00046.29 PRP88691.1 - 8.3e-12 44.8 2.2 3.1e-11 43.0 2.2 2.0 1 0 0 1 1 1 1 Homeodomain Cupin_4 PF08007.12 PRP88691.1 - 2.5e-09 37.0 0.0 1.4e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.22 PRP88691.1 - 0.00029 21.2 0.3 0.0016 18.9 0.0 2.5 3 1 0 3 3 3 1 JmjC domain, hydroxylase MTS PF05175.14 PRP88691.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PRP88691.1 - 0.0062 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DNA_pol_A PF00476.20 PRP88692.1 - 1.6e-111 373.0 0.0 2.7e-111 372.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_P_Exo PF18049.1 PRP88692.1 - 4.8e-05 22.9 0.1 0.0001 21.8 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase nu pseudo-exo LRR_8 PF13855.6 PRP88693.1 - 8.4e-25 86.3 57.8 1.8e-08 34.0 5.2 8.6 6 3 3 9 9 9 7 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP88693.1 - 4.7e-24 85.1 0.9 8.4e-24 84.2 0.9 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88693.1 - 1.5e-17 63.9 0.2 3.5e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP88693.1 - 7.2e-16 58.1 59.7 0.0027 18.1 0.6 10.8 6 3 4 12 12 12 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP88693.1 - 3.6e-06 26.8 43.6 0.75 10.6 0.1 13.6 15 1 0 15 15 15 4 Leucine Rich Repeat LRR_6 PF13516.6 PRP88693.1 - 0.052 13.6 39.5 9.5 6.6 0.6 10.6 12 0 0 12 12 12 0 Leucine Rich repeat Pkinase PF00069.25 PRP88695.1 - 2.4e-72 243.5 0.0 3.3e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88695.1 - 2.3e-38 131.9 0.0 3.8e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP88695.1 - 6.4e-21 74.8 0.2 6.2e-20 71.7 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_3 PF14593.6 PRP88695.1 - 2.4e-08 34.0 0.1 2e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.24 PRP88695.1 - 4.8e-08 33.6 1.3 1.2e-07 32.3 1.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain WD40 PF00400.32 PRP88695.1 - 6.6e-08 33.1 5.5 0.29 12.1 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat PH_11 PF15413.6 PRP88695.1 - 5.8e-07 29.9 0.9 2.5e-06 27.8 0.9 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PRP88695.1 - 0.00012 22.4 0.3 0.0017 18.7 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 PRP88695.1 - 0.0004 19.8 0.1 0.015 14.6 0.0 2.5 2 0 0 2 2 2 1 Kinase-like PH_6 PF15406.6 PRP88695.1 - 0.0023 18.2 0.0 0.0054 17.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PRP88695.1 - 0.0025 18.1 0.8 0.0093 16.2 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 PRP88695.1 - 0.0028 18.0 0.0 0.0069 16.7 0.0 1.6 1 0 0 1 1 1 1 Plant pleckstrin homology-like region Pkinase_fungal PF17667.1 PRP88695.1 - 0.0078 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Mcp5_PH PF12814.7 PRP88695.1 - 0.023 14.8 0.0 0.072 13.2 0.0 1.9 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology FTA2 PF13095.6 PRP88695.1 - 0.057 13.0 0.1 3.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ANAPC4_WD40 PF12894.7 PRP88695.1 - 0.15 12.4 0.1 10 6.5 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain NDT80_PhoG PF05224.12 PRP88696.1 - 5.6e-17 62.6 5.4 1.1e-15 58.3 0.7 3.1 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_18 PF00704.28 PRP88696.1 - 8.7e-14 51.9 0.2 2.3e-13 50.6 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Peptidase_S74 PF13884.6 PRP88696.1 - 1.4e-12 47.7 0.1 3.3e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.6 PRP88696.1 - 0.0014 17.8 0.1 0.0028 16.8 0.1 1.4 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 BTP PF05232.12 PRP88696.1 - 7.4 6.7 5.9 0.77 9.9 0.8 2.1 2 0 0 2 2 2 0 Chlorhexidine efflux transporter FAD_binding_4 PF01565.23 PRP88697.1 - 6.3e-16 58.4 0.9 1.1e-15 57.6 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PRP88697.1 - 1.1e-08 35.1 0.3 3e-08 33.6 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like P19Arf_N PF07392.12 PRP88697.1 - 0.026 14.9 0.0 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Cytokin-bind PF09265.10 PRP88697.1 - 0.036 13.5 0.1 0.056 12.8 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding CH PF00307.31 PRP88699.1 - 2.8e-13 50.0 0.0 1.1e-07 31.9 0.0 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain DUF2567 PF10821.8 PRP88699.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2567) WSC PF01822.19 PRP88700.1 - 4.3e-07 30.0 6.1 1e-06 28.8 6.1 1.7 1 0 0 1 1 1 1 WSC domain DUF4677 PF15726.5 PRP88700.1 - 0.22 11.6 0.1 0.39 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Glyco_transf_20 PF00982.21 PRP88701.1 - 8.5e-135 450.1 0.0 1.2e-134 449.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PRP88701.1 - 2.6e-55 187.1 0.0 3.9e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase WSC PF01822.19 PRP88701.1 - 4e-13 49.3 12.1 9.6e-13 48.1 12.1 1.7 1 0 0 1 1 1 1 WSC domain Hydrolase_3 PF08282.12 PRP88701.1 - 0.0027 17.5 0.0 0.79 9.4 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 PRP88701.1 - 0.0081 15.7 0.0 0.022 14.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 AAA PF00004.29 PRP88702.1 - 4.9e-16 59.4 0.0 1.1e-15 58.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP88702.1 - 7.8e-07 29.4 0.1 9.8e-05 22.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PRP88702.1 - 8.8e-06 25.8 0.0 2.1e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 PRP88702.1 - 7e-05 22.7 0.8 0.0047 16.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP88702.1 - 0.00014 22.3 0.0 0.00064 20.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 PRP88702.1 - 0.009 16.4 0.0 0.44 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PRP88702.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PRP88702.1 - 0.015 14.7 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PRP88702.1 - 0.031 14.5 0.0 0.091 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PRP88702.1 - 0.048 13.4 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 PRP88702.1 - 0.051 13.8 0.0 0.56 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.12 PRP88702.1 - 0.058 11.6 3.9 0.095 10.9 3.9 1.2 1 0 0 1 1 1 0 Nop14-like family TIP49 PF06068.13 PRP88702.1 - 0.065 12.4 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain RuvB_N PF05496.12 PRP88702.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 PRP88702.1 - 0.11 11.9 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DNA_pol_phi PF04931.13 PRP88702.1 - 5.3 5.0 9.3 8.5 4.3 9.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi IKI3 PF04762.12 PRP88705.1 - 3.7e-239 796.4 0.0 2.6e-213 710.8 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 PRP88705.1 - 1.3e-05 25.4 0.0 0.45 10.9 0.0 4.2 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DnaJ_CXXCXGXG PF00684.19 PRP88705.1 - 0.0093 16.3 4.7 0.0093 16.3 4.7 5.7 6 0 0 6 6 6 1 DnaJ central domain Polysacc_deac_1 PF01522.21 PRP88705.1 - 0.16 11.8 0.0 0.51 10.2 0.0 1.8 1 0 0 1 1 1 0 Polysaccharide deacetylase SIMPL PF04402.14 PRP88705.1 - 8.5 6.8 7.8 9.6 6.6 5.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Homeodomain PF00046.29 PRP88706.1 - 1.7e-12 46.9 8.8 2.6e-12 46.4 8.8 1.3 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 PRP88706.1 - 0.0005 19.5 0.3 0.00094 18.6 0.3 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 PRP88706.1 - 0.097 12.6 3.1 0.17 11.8 3.0 1.5 1 1 0 1 1 1 0 Homeobox KN domain DUF29 PF01724.16 PRP88706.1 - 0.13 12.4 4.8 0.18 12.0 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF29 Peptidase_C1 PF00112.23 PRP88708.1 - 2.6e-48 165.0 4.0 2.6e-48 165.0 4.0 2.3 3 0 0 3 3 3 1 Papain family cysteine protease CAP PF00188.26 PRP88708.1 - 3.3e-15 57.0 3.7 3.3e-15 57.0 3.7 2.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family WSC PF01822.19 PRP88708.1 - 4.1e-12 46.1 39.8 1.7e-11 44.1 16.7 4.4 4 1 0 4 4 4 2 WSC domain HLH PF00010.26 PRP88708.1 - 1.6e-06 28.0 0.3 2.9e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_C1_2 PF03051.15 PRP88708.1 - 0.00032 19.6 3.0 0.005 15.7 0.8 2.3 2 0 0 2 2 2 1 Peptidase C1-like family CDtoxinA PF03498.14 PRP88708.1 - 0.011 15.4 3.6 0.026 14.1 0.4 2.9 3 0 0 3 3 3 0 Cytolethal distending toxin A/C domain His_Phos_1 PF00300.22 PRP88708.1 - 0.018 14.7 0.0 0.049 13.3 0.0 1.6 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) Herpes_UL6 PF01763.16 PRP88708.1 - 0.14 10.7 0.6 0.22 10.0 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Flg_new PF09479.10 PRP88708.1 - 0.81 9.9 5.8 0.35 11.1 0.5 3.2 3 0 0 3 3 3 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) Dmrt1 PF12374.8 PRP88708.1 - 8.2 7.0 10.3 2.5 8.6 0.3 3.6 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 RecA PF00154.21 PRP88709.1 - 5.3e-127 422.7 1.2 6.8e-127 422.4 1.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 PRP88709.1 - 4.1e-11 42.6 0.3 2.9e-10 39.9 0.3 1.9 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 PRP88709.1 - 2.1e-09 37.1 1.5 4.7e-08 32.7 1.5 2.7 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 PRP88709.1 - 1.1e-05 25.5 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 PRP88709.1 - 1.8e-05 24.5 0.0 5.9e-05 22.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 PRP88709.1 - 4.2e-05 24.0 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CobU PF02283.16 PRP88709.1 - 9e-05 22.1 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_16 PF13191.6 PRP88709.1 - 0.00019 21.8 0.2 0.00044 20.7 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 PRP88709.1 - 0.00028 20.5 0.1 0.0015 18.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_35 PF14516.6 PRP88709.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 PRP88709.1 - 0.043 14.1 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PRP88709.1 - 0.054 13.5 0.0 0.17 11.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain DnaB_C PF03796.15 PRP88709.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain ABC_tran PF00005.27 PRP88709.1 - 0.092 13.3 0.0 0.23 12.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter CLP1_P PF16575.5 PRP88709.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop zf-H2C2_2 PF13465.6 PRP88711.1 - 1e-14 54.2 15.5 2.7e-07 30.7 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 PRP88711.1 - 1.5e-10 40.9 25.5 0.00013 22.2 2.9 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP88711.1 - 1.3e-09 38.1 17.6 0.00015 22.3 0.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PRP88711.1 - 0.00012 22.3 7.7 0.0017 18.6 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP88711.1 - 0.0018 18.6 11.1 0.095 13.1 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 PRP88711.1 - 0.0047 16.7 12.2 0.0094 15.7 0.2 3.9 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_aberr PF17017.5 PRP88711.1 - 0.017 15.3 1.4 6.1 6.9 0.3 2.5 2 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 PRP88711.1 - 0.022 14.7 0.1 0.022 14.7 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger CHORD PF04968.12 PRP88711.1 - 1.7 9.4 7.3 4.6 8.0 0.3 2.5 2 0 0 2 2 2 0 CHORD Hus1 PF04005.12 PRP88712.1 - 3.8e-72 242.9 0.7 4.6e-72 242.6 0.7 1.1 1 0 0 1 1 1 1 Hus1-like protein PCNA_C PF02747.15 PRP88712.1 - 0.1 12.8 0.3 0.26 11.5 0.2 1.8 2 1 0 2 2 2 0 Proliferating cell nuclear antigen, C-terminal domain DHDPS PF00701.22 PRP88713.1 - 2.1e-44 151.4 0.0 2.6e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 PRP88713.1 - 0.0049 16.4 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DeoC PF01791.9 PRP88713.1 - 0.029 14.0 0.2 0.042 13.4 0.2 1.3 1 0 0 1 1 1 0 DeoC/LacD family aldolase Pkinase_Tyr PF07714.17 PRP88714.1 - 1e-50 172.5 0.0 1.4e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88714.1 - 2.2e-45 155.1 0.0 2.9e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 PRP88714.1 - 8.4e-13 48.2 0.0 1.9e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 PRP88714.1 - 0.0015 18.4 0.0 0.0053 16.6 0.0 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain CH PF00307.31 PRP88716.1 - 1.4e-28 99.3 0.0 4e-13 49.5 0.0 2.6 2 1 0 2 2 2 2 Calponin homology (CH) domain Filamin PF00630.19 PRP88716.1 - 3.1e-27 95.4 41.9 6.8e-07 30.1 1.0 9.9 6 3 3 9 9 9 9 Filamin/ABP280 repeat Invasin_D3 PF09134.10 PRP88716.1 - 1.9e-14 53.7 54.2 0.0012 19.1 2.9 9.2 6 2 3 9 9 9 5 Invasin, domain 3 TRIQK PF15168.6 PRP88716.1 - 0.0009 19.1 0.1 0.0035 17.2 0.1 2.0 1 0 0 1 1 1 1 Triple QxxK/R motif-containing protein family FixH PF05751.11 PRP88716.1 - 0.0029 17.6 13.0 4.1 7.4 0.0 6.9 7 1 2 9 9 9 1 FixH Trypan_PARP PF05887.11 PRP88716.1 - 0.0044 17.0 14.3 0.018 15.0 14.3 2.0 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) CAMSAP_CH PF11971.8 PRP88716.1 - 0.033 14.0 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain DUF5370 PF17340.2 PRP88716.1 - 0.034 14.0 0.1 8.8 6.3 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5370) HATPase_c_2 PF13581.6 PRP88716.1 - 0.15 12.0 0.9 36 4.3 0.0 3.6 2 1 1 3 3 3 0 Histidine kinase-like ATPase domain DUF4479 PF14794.6 PRP88716.1 - 1.3 8.9 3.7 50 3.9 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4479) Glucodextran_B PF09136.10 PRP88716.1 - 3 8.3 15.5 30 5.1 0.0 6.4 5 1 1 6 6 6 0 Glucodextranase, domain B Glyco_hydro_127 PF07944.12 PRP88719.1 - 2.9e-34 118.5 0.1 1.1e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 PAN_4 PF14295.6 PRP88719.1 - 3.9e-10 39.5 3.3 8.1e-10 38.5 3.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PRP88719.1 - 0.017 15.1 0.6 0.037 14.0 0.6 1.5 1 0 0 1 1 1 0 PAN domain ACOX PF01756.19 PRP88722.1 - 2.9e-52 176.9 0.0 5.2e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PRP88722.1 - 5.2e-17 61.8 0.1 9.8e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Ank_2 PF12796.7 PRP88722.1 - 2.3e-12 47.3 0.0 1.2e-06 29.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Acyl-CoA_ox_N PF14749.6 PRP88722.1 - 8e-12 45.8 0.0 2.3e-11 44.3 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Ank_4 PF13637.6 PRP88722.1 - 8e-06 26.3 0.1 0.014 16.0 0.1 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP88722.1 - 4.9e-05 23.5 0.1 1 9.8 0.0 4.9 2 1 3 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88722.1 - 0.00033 20.9 0.0 7.3 7.5 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat Acyl-CoA_dh_1 PF00441.24 PRP88722.1 - 0.003 17.8 0.0 0.0086 16.3 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ank PF00023.30 PRP88722.1 - 0.011 16.1 0.1 6 7.5 0.1 4.2 4 0 0 4 4 4 0 Ankyrin repeat Vps53_N PF04100.12 PRP88723.1 - 1.7e-86 290.6 9.4 3.4e-86 289.6 9.4 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 PRP88723.1 - 3.2e-09 36.5 4.8 8e-09 35.2 4.8 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Sec5 PF15469.6 PRP88723.1 - 0.0025 17.6 9.6 0.0042 16.9 3.5 3.4 3 1 0 3 3 3 1 Exocyst complex component Sec5 VPS53_C PF16854.5 PRP88723.1 - 0.009 15.9 0.1 0.03 14.2 0.1 2.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus MCPVI PF02993.14 PRP88723.1 - 0.017 14.9 0.2 0.2 11.5 0.0 2.5 3 0 0 3 3 3 0 Minor capsid protein VI DUF2884 PF11101.8 PRP88723.1 - 0.018 14.6 0.2 0.048 13.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF4208 PF13907.6 PRP88723.1 - 0.19 12.2 5.1 1.2 9.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4208) Elongin_A PF06881.11 PRP88724.1 - 1.1e-09 38.8 2.3 1.8e-09 38.1 2.3 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Snf7 PF03357.21 PRP88724.1 - 2 8.0 6.8 3.5 7.2 6.8 1.4 1 1 0 1 1 1 0 Snf7 AAA_16 PF13191.6 PRP88725.1 - 6.7e-35 121.0 0.0 1.8e-34 119.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP88725.1 - 4.2e-21 75.5 0.0 8.8e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88725.1 - 8.5e-13 48.2 0.0 1.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_2 PF13185.6 PRP88725.1 - 9.1e-09 35.7 0.0 1.8e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain U-box PF04564.15 PRP88725.1 - 7.5e-07 29.2 0.2 2.2e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 U-box domain GAF PF01590.26 PRP88725.1 - 5e-06 27.2 0.0 1.1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 PRP88725.1 - 0.00079 18.7 0.6 1.6 7.8 0.1 3.0 3 0 0 3 3 3 2 NB-ARC domain AAA_22 PF13401.6 PRP88725.1 - 0.0014 18.9 0.0 0.11 12.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain Kinase-like PF14531.6 PRP88725.1 - 0.0016 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like zf-Nse PF11789.8 PRP88725.1 - 0.011 15.6 0.6 0.034 14.0 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RsgA_GTPase PF03193.16 PRP88725.1 - 0.013 15.4 0.1 0.049 13.5 0.1 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 PRP88725.1 - 0.036 14.6 0.0 0.19 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 PRP88725.1 - 0.068 13.1 0.2 0.51 10.2 0.1 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Self-incomp_S1 PF05938.11 PRP88725.1 - 0.15 12.6 0.3 0.55 10.8 0.3 1.9 1 0 0 1 1 1 0 Plant self-incompatibility protein S1 zf-RING_UBOX PF13445.6 PRP88725.1 - 0.42 10.7 5.1 0.13 12.3 1.1 2.3 2 0 0 2 2 2 0 RING-type zinc-finger HAD PF12710.7 PRP88726.1 - 2e-07 31.6 0.0 8.1e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RasGEF PF00617.19 PRP88728.1 - 9.4e-32 110.6 0.5 9.4e-32 110.6 0.5 1.7 2 0 0 2 2 2 1 RasGEF domain WD40 PF00400.32 PRP88729.1 - 3.3e-46 154.3 17.9 3.3e-10 40.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP88729.1 - 5.3e-13 49.1 0.8 0.042 14.1 0.0 6.2 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PRP88729.1 - 1.7e-09 37.4 0.6 0.0012 18.3 0.6 3.1 2 1 1 3 3 3 3 WD40-like domain PQQ_2 PF13360.6 PRP88729.1 - 0.00058 19.5 0.0 0.0025 17.4 0.0 2.4 1 1 0 1 1 1 1 PQQ-like domain Kelch_6 PF13964.6 PRP88729.1 - 0.00062 20.0 1.9 6.3 7.2 0.0 4.5 4 0 0 4 4 4 1 Kelch motif Cytochrom_D1 PF02239.16 PRP88729.1 - 0.0013 17.3 0.3 0.74 8.3 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain VID27 PF08553.10 PRP88729.1 - 0.0025 16.9 0.1 0.29 10.1 0.0 2.3 1 1 1 2 2 2 1 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 PRP88729.1 - 0.0067 15.5 0.1 0.009 15.1 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region Nup160 PF11715.8 PRP88729.1 - 0.0083 14.8 1.5 1.6 7.2 0.1 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 PRP88729.1 - 0.01 15.7 0.1 0.77 9.6 0.0 3.0 1 1 3 4 4 4 0 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 PRP88729.1 - 0.014 13.8 0.1 1.1 7.5 0.0 2.2 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF5046 PF16465.5 PRP88729.1 - 0.023 14.2 0.3 0.1 12.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) FAD_binding_3 PF01494.19 PRP88730.1 - 7.9e-18 64.8 0.1 1.2e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 PRP88730.1 - 0.00044 19.4 0.0 0.017 14.2 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase EF-hand_1 PF00036.32 PRP88733.1 - 1.4e-10 40.0 5.3 0.00011 21.4 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PRP88733.1 - 1.6e-09 38.1 0.2 0.003 18.0 0.2 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP88733.1 - 5.1e-08 32.2 2.4 0.0059 16.4 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PRP88733.1 - 3.4e-06 26.3 4.7 0.0019 17.6 0.3 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PRP88733.1 - 0.0026 17.6 6.5 0.024 14.5 0.3 3.2 2 1 1 3 3 3 1 EF-hand domain pair G10 PF01125.17 PRP88733.1 - 0.0097 15.7 5.4 0.02 14.6 5.4 1.5 1 0 0 1 1 1 1 G10 protein Pox_MCEL PF03291.16 PRP88735.1 - 6.7e-73 245.7 0.0 1.2e-72 244.8 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 PRP88735.1 - 2.8e-07 31.1 0.0 5.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PRP88735.1 - 6.5e-06 26.1 0.0 1.5e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP88735.1 - 0.00012 22.8 0.0 0.00024 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PRP88735.1 - 0.00044 20.9 0.0 0.00073 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.32 PRP88736.1 - 4e-21 74.9 10.0 0.00073 20.3 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP88736.1 - 5.9e-09 36.1 0.6 0.00092 19.5 0.0 4.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PRP88736.1 - 5.1e-05 23.0 0.9 0.0003 20.5 1.0 1.9 1 1 1 2 2 2 2 PQQ-like domain Ge1_WD40 PF16529.5 PRP88736.1 - 0.00058 18.9 0.1 9 5.1 0.0 3.6 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PRP88736.1 - 0.0059 16.0 0.4 0.15 11.4 0.1 2.1 1 1 1 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 PRP88736.1 - 0.011 16.3 0.1 4.4 7.9 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 PRP88736.1 - 0.12 12.3 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Sigma70_ner PF04546.13 PRP88736.1 - 1.2 9.0 10.1 1.1 9.2 0.3 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region SCIMP PF15050.6 PRP88737.1 - 0.0043 17.5 0.6 0.0062 17.0 0.6 1.2 1 0 0 1 1 1 1 SCIMP protein DUF2062 PF09835.9 PRP88737.1 - 0.057 13.3 0.0 0.066 13.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) ATP-synt_S1 PF05827.12 PRP88737.1 - 0.088 12.6 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) MR_MLE_C PF13378.6 PRP88738.1 - 1.3e-41 142.6 0.1 7.8e-41 140.0 0.1 2.1 1 1 0 1 1 1 1 Enolase C-terminal domain-like GFA PF04828.14 PRP88738.1 - 2e-16 60.1 0.8 4.3e-16 59.0 0.8 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MAAL_C PF07476.11 PRP88738.1 - 0.00039 19.6 0.0 0.028 13.6 0.0 2.2 2 0 0 2 2 2 2 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 PRP88738.1 - 0.0024 18.1 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Y_phosphatase PF00102.27 PRP88739.1 - 6.3e-70 235.4 0.1 7.4e-70 235.2 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 PRP88739.1 - 0.00098 18.9 0.1 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PRP88739.1 - 0.0019 18.3 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PRP88739.1 - 0.006 16.6 0.0 0.008 16.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family TFIIA PF03153.13 PRP88740.1 - 0.0016 18.5 29.9 0.0016 18.5 29.9 2.1 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit Baculo_PEP_C PF04513.12 PRP88740.1 - 0.13 12.4 17.6 0.75 9.8 2.6 3.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 PRP88740.1 - 0.74 10.1 19.7 1 9.7 0.4 4.7 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DnaJ PF00226.31 PRP88742.1 - 3.4e-20 71.9 0.2 4.9e-20 71.4 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 PRP88742.1 - 9.3e-15 54.1 0.8 1.4e-14 53.5 0.8 1.3 1 0 0 1 1 1 1 CSL zinc finger PM0188 PF11477.8 PRP88742.1 - 0.0027 16.9 0.0 0.0033 16.6 0.0 1.0 1 0 0 1 1 1 1 Sialyltransferase PMO188 Endonuclease_NS PF01223.23 PRP88743.1 - 0.00022 21.1 0.0 0.00045 20.1 0.0 1.5 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease PP1_bind PF15276.6 PRP88743.1 - 0.1 12.9 0.0 0.1 12.9 0.0 3.1 2 1 0 2 2 2 0 Protein phosphatase 1 binding DUF4140 PF13600.6 PRP88745.1 - 0.0079 16.6 1.5 0.65 10.5 0.1 2.4 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) DUF2730 PF10805.8 PRP88745.1 - 0.099 12.7 0.4 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ATG16 PF08614.11 PRP88745.1 - 3.9 7.7 7.7 0.43 10.8 2.7 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) HATPase_c PF02518.26 PRP88747.1 - 8.9e-26 90.6 3.1 9.7e-26 90.5 1.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP88747.1 - 8.2e-23 80.7 0.6 8.2e-23 80.7 0.6 2.3 3 0 0 3 3 3 1 Response regulator receiver domain PHY PF00360.20 PRP88747.1 - 3.4e-20 72.1 0.0 6.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HisKA PF00512.25 PRP88747.1 - 5.8e-16 58.3 0.6 1.4e-15 57.1 0.6 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 PRP88747.1 - 1.4e-14 54.9 0.0 2.9e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 PRP88747.1 - 1.3e-08 35.5 0.0 2.3e-07 31.4 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 PRP88747.1 - 0.0021 18.3 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 PRP88747.1 - 0.072 13.1 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 PRP88747.1 - 0.15 12.4 0.0 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 PAS fold ADP_PFK_GK PF04587.15 PRP88748.1 - 1.7e-110 369.5 0.0 5e-110 368.0 0.0 1.6 1 1 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region B_solenoid_dext PF18841.1 PRP88748.1 - 0.44 10.9 0.1 0.44 10.9 0.1 1.8 2 0 0 2 2 2 0 Beta solenoid repeat from Dextranase SH3_9 PF14604.6 PRP88749.1 - 1.1e-08 34.7 0.1 2.2e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP88749.1 - 2.1e-06 27.3 0.3 5.9e-06 25.8 0.1 1.9 2 0 0 2 2 2 1 SH3 domain Lzipper-MIP1 PF14389.6 PRP88749.1 - 1.2 9.5 12.2 3.1 8.1 3.5 2.6 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Tweety PF04906.13 PRP88749.1 - 5.6 5.5 6.3 1.5 7.4 1.9 1.9 1 1 1 2 2 2 0 Tweety DUF1664 PF07889.12 PRP88749.1 - 6.4 6.8 13.0 2.9 8.0 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Aldedh PF00171.22 PRP88750.1 - 4.1e-76 256.4 0.0 4.9e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L18_c PF14204.6 PRP88751.1 - 1.6e-32 112.3 0.9 4.3e-32 110.9 0.9 1.7 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L5e PF17144.4 PRP88751.1 - 3.3e-24 85.7 0.2 2.3e-19 70.0 0.0 2.7 2 1 1 3 3 3 2 Ribosomal large subunit proteins 60S L5, and 50S L18 FAM86 PF14904.6 PRP88751.1 - 0.029 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function Myosin_head PF00063.21 PRP88752.1 - 1.9e-12 46.3 0.0 2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DDE_Tnp_4 PF13359.6 PRP88753.1 - 1.1e-05 25.1 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 PRP88753.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_6 PF13751.6 PRP88753.1 - 0.006 16.8 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Mannitol_dh_C PF08125.13 PRP88755.1 - 1.5e-61 208.0 0.0 3.9e-61 206.7 0.0 1.8 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 PRP88755.1 - 2e-41 141.6 0.6 7.3e-41 139.8 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain Sde2_N_Ubi PF13019.6 PRP88755.1 - 2e-22 79.8 1.3 2e-22 79.8 1.3 2.6 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 PRP88755.1 - 5e-22 77.3 0.5 1e-21 76.3 0.5 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal Acyl-CoA_dh_1 PF00441.24 PRP88756.1 - 2.1e-31 109.2 0.2 3e-31 108.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 PRP88756.1 - 2.5e-21 75.6 0.1 5.3e-21 74.6 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 PRP88756.1 - 3.1e-17 62.5 0.3 5.5e-17 61.8 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PRP88756.1 - 5.4e-17 62.5 0.0 1.2e-16 61.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 PRP88756.1 - 2.9e-06 27.6 0.0 6.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EFP_N PF08207.12 PRP88756.1 - 0.11 12.6 0.1 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Ldh_1_C PF02866.18 PRP88757.1 - 2.3e-35 122.0 0.0 5.1e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PRP88757.1 - 4.3e-34 117.6 0.3 7.7e-34 116.8 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Acyltransferase PF01553.21 PRP88757.1 - 1.8e-16 60.0 0.0 4.4e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase C1_1 PF00130.22 PRP88757.1 - 2.2e-09 37.1 0.6 4.9e-09 36.0 0.6 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Clathrin_H_link PF13838.6 PRP88757.1 - 4.7e-08 32.8 0.0 1.3e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Clathrin-H-link F-box-like PF12937.7 PRP88757.1 - 2.5e-07 30.5 0.6 6.2e-07 29.2 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP88757.1 - 5e-05 23.1 0.4 0.00025 20.8 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 PRP88757.1 - 0.015 15.2 0.0 0.062 13.2 0.0 2.1 2 0 0 2 2 2 0 F-box PHD PF00628.29 PRP88757.1 - 0.1 12.5 0.5 0.24 11.3 0.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-C4H2 PF10146.9 PRP88757.1 - 0.44 10.8 3.5 3.9 7.7 1.3 2.7 3 0 0 3 3 3 0 Zinc finger-containing protein HSP70 PF00012.20 PRP88760.1 - 6e-155 516.8 7.2 7.4e-155 516.5 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PRP88760.1 - 5.3e-14 51.8 2.4 2.1e-13 49.8 2.4 2.0 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 PRP88760.1 - 0.0001 22.7 0.9 0.52 10.8 0.1 3.2 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 PRP88760.1 - 0.00084 18.7 0.1 0.0021 17.4 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 PRP88760.1 - 0.0085 15.6 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DUF2815 PF10991.8 PRP88760.1 - 0.23 11.4 2.4 0.24 11.3 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2815) Kelch_6 PF13964.6 PRP88761.1 - 3.6e-33 112.7 11.1 1.3e-10 41.2 0.0 6.2 6 1 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 PRP88761.1 - 3.5e-30 103.3 6.3 1.9e-11 43.4 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 PRP88761.1 - 2.3e-28 97.7 5.8 7.1e-08 32.3 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 PRP88761.1 - 7.8e-27 93.0 16.7 5.7e-09 36.0 0.0 6.8 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP88761.1 - 3e-25 87.2 10.4 3.7e-11 42.5 0.1 6.1 6 2 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 PRP88761.1 - 3.1e-22 78.3 20.1 4.4e-08 33.0 0.2 6.6 6 1 1 7 7 7 5 Galactose oxidase, central domain F-box-like PF12937.7 PRP88761.1 - 5.2e-07 29.4 1.7 7.4e-07 29.0 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP88761.1 - 9.4e-05 22.2 0.3 0.00017 21.4 0.3 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP88761.1 - 0.0023 17.8 0.0 0.0059 16.5 0.0 1.7 1 0 0 1 1 1 1 F-box Elongin_A PF06881.11 PRP88761.1 - 0.045 14.3 0.2 0.1 13.1 0.2 1.5 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PQQ_3 PF13570.6 PRP88761.1 - 0.074 13.6 4.8 2.9 8.5 0.0 4.8 5 1 1 6 6 6 0 PQQ-like domain Mito_carr PF00153.27 PRP88762.1 - 3.5e-32 110.2 6.5 4.4e-18 65.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_2 PF03446.15 PRP88763.1 - 2.2e-20 73.4 0.0 3.7e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PRP88763.1 - 2e-09 37.8 0.0 4.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 PRP88763.1 - 3.9e-05 23.1 0.0 6.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PRP88763.1 - 7.5e-05 22.4 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 PRP88763.1 - 0.00012 22.5 0.3 0.00038 21.0 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 PRP88763.1 - 0.0016 18.5 0.1 0.0028 17.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 PRP88763.1 - 0.12 13.2 0.1 0.3 11.9 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Usp PF00582.26 PRP88764.1 - 4e-18 66.3 0.1 6.7e-18 65.5 0.1 1.4 1 0 0 1 1 1 1 Universal stress protein family TetR_C_28 PF17937.1 PRP88764.1 - 0.0046 17.4 0.1 0.0088 16.5 0.1 1.4 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Peptidase_U57 PF05582.12 PRP88764.1 - 0.051 12.8 2.7 0.44 9.8 2.7 2.0 1 1 0 1 1 1 0 YabG peptidase U57 Toprim_3 PF13362.6 PRP88764.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Toprim domain Chorismate_bind PF00425.18 PRP88765.1 - 5.6e-87 291.6 0.0 8.3e-87 291.0 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 PRP88765.1 - 7.5e-47 159.6 0.0 1.2e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 PRP88765.1 - 1.5e-18 67.4 0.0 5.5e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 PRP88765.1 - 0.00036 20.4 0.8 0.0022 17.8 0.8 2.1 1 1 0 1 1 1 1 Peptidase C26 Beta_helix PF13229.6 PRP88767.1 - 0.0016 18.3 19.6 0.0016 18.3 19.6 3.1 2 1 0 2 2 2 1 Right handed beta helix region FAM165 PF14981.6 PRP88767.1 - 0.037 13.8 0.1 0.095 12.5 0.1 1.7 1 0 0 1 1 1 0 FAM165 family v110 PF01639.17 PRP88767.1 - 0.044 13.7 7.4 0.14 12.1 7.4 1.8 1 0 0 1 1 1 0 Viral family 110 BChl_A PF02327.17 PRP88767.1 - 0.088 11.6 0.3 0.16 10.8 0.3 1.3 1 0 0 1 1 1 0 Bacteriochlorophyll A protein NosD PF05048.13 PRP88767.1 - 4.5 6.5 20.7 0.053 12.8 10.1 2.4 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) DNA_pol_A PF00476.20 PRP88768.1 - 7e-103 344.6 0.1 1.8e-102 343.2 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 PRP88768.1 - 0.087 12.5 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease polyprenyl_synt PF00348.17 PRP88769.1 - 2.7e-56 190.5 0.0 3.3e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase C2 PF00168.30 PRP88770.1 - 1.8e-42 143.8 0.9 8.2e-23 80.7 0.0 3.6 3 0 0 3 3 3 2 C2 domain GRAM PF02893.20 PRP88770.1 - 4.5e-10 39.4 0.3 2.6e-06 27.3 0.1 2.9 2 0 0 2 2 2 2 GRAM domain Membr_traf_MHD PF10540.9 PRP88770.1 - 9e-07 29.2 0.2 0.013 15.7 0.0 3.5 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain DUF3040 PF11239.8 PRP88770.1 - 0.074 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) ZapB PF06005.12 PRP88771.1 - 0.0015 19.0 1.8 0.0031 17.9 1.8 1.5 1 0 0 1 1 1 1 Cell division protein ZapB NRBF2 PF08961.10 PRP88771.1 - 0.014 15.0 1.5 0.018 14.6 0.3 1.7 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 PRP88771.1 - 0.026 14.7 1.4 0.058 13.6 1.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Pkinase PF00069.25 PRP88772.1 - 1.9e-65 220.9 0.0 4.4e-65 219.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88772.1 - 1.2e-49 169.0 0.8 1.7e-49 168.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RNA_polI_A34 PF08208.11 PRP88772.1 - 6.4e-06 26.4 10.6 6.4e-06 26.4 10.6 3.3 1 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 Kinase-like PF14531.6 PRP88772.1 - 0.00018 21.0 0.0 0.0075 15.6 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 PRP88772.1 - 0.0019 17.3 0.3 0.0032 16.6 0.3 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 PRP88772.1 - 0.017 14.1 3.1 0.022 13.7 0.1 2.6 2 1 0 2 2 2 0 Haspin like kinase domain LAP1C PF05609.12 PRP88772.1 - 0.069 12.2 30.5 0.071 12.2 15.1 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) ATP-synt_8 PF00895.20 PRP88772.1 - 0.31 11.5 1.7 0.67 10.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 DUF5549 PF17703.1 PRP88772.1 - 0.95 9.1 5.1 0.47 10.1 2.0 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5549) SID-1_RNA_chan PF13965.6 PRP88772.1 - 0.99 7.7 3.5 1.7 7.0 3.5 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 C2 PF00168.30 PRP88773.1 - 9.5e-13 48.3 0.0 1.9e-08 34.5 0.0 2.8 2 0 0 2 2 2 2 C2 domain Anp1 PF03452.14 PRP88774.1 - 0.17 11.3 5.4 0.18 11.2 5.4 1.0 1 0 0 1 1 1 0 Anp1 DUF1666 PF07891.12 PRP88774.1 - 0.84 9.3 9.1 0.86 9.2 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) DUF3671 PF12420.8 PRP88774.1 - 1.3 9.1 5.6 1.7 8.8 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF1918 PF08940.11 PRP88775.1 - 0.0012 18.4 0.2 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1918) DUF789 PF05623.12 PRP88775.1 - 0.055 13.1 2.3 5.1 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF789) Patatin PF01734.22 PRP88777.1 - 5.9e-22 78.9 1.2 1.7e-21 77.4 1.2 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase LRV_FeS PF05484.11 PRP88779.1 - 0.065 13.2 0.1 8.2 6.5 0.1 2.3 1 1 1 2 2 2 0 LRV protein FeS4 cluster DrrA_P4M PF14860.6 PRP88779.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Citrate_synt PF00285.21 PRP88780.1 - 2.4e-106 355.8 0.0 4e-106 355.1 0.0 1.3 2 0 0 2 2 2 1 Citrate synthase, C-terminal domain Myb_DNA-binding PF00249.31 PRP88781.1 - 2.8e-11 43.4 0.6 6.4e-11 42.3 0.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP88781.1 - 0.019 15.2 0.1 0.05 13.9 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PRP88781.1 - 0.93 9.4 8.1 0.036 13.9 1.1 2.4 2 0 0 2 2 2 0 Myb DNA-binding like PLAC8 PF04749.17 PRP88782.1 - 1e-17 65.0 14.3 1.2e-17 64.7 14.3 1.1 1 0 0 1 1 1 1 PLAC8 family LEM PF03020.15 PRP88782.1 - 0.17 11.5 0.3 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 LEM domain ubiquitin PF00240.23 PRP88783.1 - 0.00015 21.4 0.1 0.00027 20.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 PRP88783.1 - 0.00034 20.7 0.1 0.00074 19.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PRP88783.1 - 0.00079 20.0 2.2 0.0017 18.9 2.2 1.6 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF3188 PF11384.8 PRP88783.1 - 0.34 10.6 2.2 2.5 7.9 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3188) MtrF PF09472.10 PRP88784.1 - 0.15 11.4 0.9 0.32 10.4 0.0 2.0 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) RIB43A PF05914.12 PRP88785.1 - 2.7e-81 273.2 67.7 3.3e-81 273.0 67.7 1.0 1 0 0 1 1 1 1 RIB43A Cyt-b5 PF00173.28 PRP88786.1 - 1.8e-07 31.2 0.0 3.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ubiquitin PF00240.23 PRP88786.1 - 3.1e-05 23.6 0.0 0.0001 22.0 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 PRP88786.1 - 0.02 14.7 0.7 0.098 12.5 0.7 2.0 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RPW8 PF05659.11 PRP88787.1 - 0.0004 20.1 0.7 0.0004 20.1 0.7 2.2 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Lectin_N PF03954.14 PRP88787.1 - 0.0056 16.4 1.0 0.0056 16.4 1.0 1.6 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain Spectrin PF00435.21 PRP88787.1 - 0.012 16.1 1.5 0.012 16.1 1.5 2.4 2 1 0 2 2 2 0 Spectrin repeat Focal_AT PF03623.13 PRP88787.1 - 0.013 15.4 3.2 0.98 9.4 0.5 2.3 1 1 0 2 2 2 0 Focal adhesion targeting region Fib_alpha PF08702.10 PRP88787.1 - 0.033 14.4 0.3 0.033 14.4 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2810 PF10928.8 PRP88787.1 - 0.14 12.2 0.3 2.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2810) DUF2203 PF09969.9 PRP88787.1 - 0.63 10.8 6.3 0.13 12.9 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SLX9 PF15341.6 PRP88787.1 - 1.1 9.7 10.5 5.5 7.4 10.5 2.0 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 GlutR_dimer PF00745.20 PRP88787.1 - 2.1 8.9 7.8 0.7 10.4 0.4 2.3 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain YabA PF06156.13 PRP88787.1 - 3.4 8.3 8.4 0.2 12.3 1.2 2.2 2 1 0 2 2 2 0 Initiation control protein YabA PP28 PF10252.9 PRP88788.1 - 3.1e-07 30.7 20.8 3.1e-07 30.7 20.8 4.4 3 2 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 SDA1 PF05285.12 PRP88788.1 - 0.18 11.2 40.0 0.22 10.9 40.0 1.2 1 0 0 1 1 1 0 SDA1 Aph-1 PF06105.12 PRP88789.1 - 1e-56 192.0 22.9 1.2e-56 191.7 22.9 1.0 1 0 0 1 1 1 1 Aph-1 protein LIM PF00412.22 PRP88789.1 - 0.051 13.8 1.0 0.094 13.0 1.0 1.4 1 0 0 1 1 1 0 LIM domain Saf_2TM PF18303.1 PRP88789.1 - 3.9 7.0 5.8 0.3 10.7 0.6 1.8 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Sua5_yciO_yrdC PF01300.18 PRP88790.1 - 1.4e-57 194.1 0.0 2.6e-57 193.2 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 PRP88790.1 - 3.7e-30 105.2 0.0 5.3e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding FAS_meander PF17951.1 PRP88790.1 - 0.19 11.5 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain PAXNEB PF05625.11 PRP88791.1 - 1.5e-73 248.1 0.1 2e-73 247.7 0.1 1.0 1 0 0 1 1 1 1 PAXNEB protein ST7 PF04184.12 PRP88792.1 - 6.1e-16 58.0 3.3 5.7e-08 31.7 0.2 3.1 2 1 0 2 2 2 2 ST7 protein zf-MYND PF01753.18 PRP88792.1 - 1.9e-08 34.2 9.5 4.8e-08 33.0 9.5 1.8 1 0 0 1 1 1 1 MYND finger TPR_14 PF13428.6 PRP88792.1 - 1.4e-07 31.7 4.1 2.2 9.3 0.0 5.9 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP88792.1 - 5.7e-06 25.9 8.5 0.037 13.9 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PRP88792.1 - 8.2e-05 23.0 3.4 0.16 12.5 0.1 4.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP88792.1 - 0.0018 18.9 2.8 20 5.9 0.0 4.6 4 2 0 4 4 4 0 Tetratricopeptide repeat CobU PF02283.16 PRP88792.1 - 0.0032 17.0 0.8 1.5 8.4 0.1 2.4 2 0 0 2 2 2 2 Cobinamide kinase / cobinamide phosphate guanyltransferase TPR_17 PF13431.6 PRP88792.1 - 0.0048 17.2 2.9 0.6 10.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP88792.1 - 0.043 13.9 11.1 0.61 10.3 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_34 PF05637.12 PRP88792.1 - 0.045 13.5 0.2 11 5.6 0.0 2.4 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family DUF3151 PF11349.8 PRP88792.1 - 0.13 12.4 2.0 15 5.7 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3151) ANAPC3 PF12895.7 PRP88792.1 - 0.31 11.3 10.8 5 7.4 0.1 4.6 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 PRP88792.1 - 1.9 8.8 6.6 11 6.4 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_C54 PF03416.19 PRP88793.1 - 2e-85 286.5 0.3 2.6e-85 286.2 0.3 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 PRP88793.1 - 0.025 14.1 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C78 OmpH PF03938.14 PRP88794.1 - 0.011 16.1 1.0 0.012 15.9 1.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CdvA PF18822.1 PRP88794.1 - 0.017 14.9 1.6 0.022 14.6 1.6 1.1 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Spidroin_MaSp PF11260.8 PRP88794.1 - 0.026 14.8 0.5 0.052 13.9 0.1 1.6 1 1 1 2 2 2 0 Major ampullate spidroin 1 and 2 MetOD2 PF18548.1 PRP88794.1 - 0.027 14.6 1.7 0.086 13.0 1.2 1.8 1 1 1 2 2 2 0 Metanogen output domain 2 NgoMIV_restric PF09015.10 PRP88794.1 - 0.027 13.6 0.7 0.026 13.6 0.7 1.0 1 0 0 1 1 1 0 NgoMIV restriction enzyme VHS PF00790.19 PRP88794.1 - 0.032 14.1 1.0 0.038 13.8 1.0 1.1 1 0 0 1 1 1 0 VHS domain Utp13 PF08625.11 PRP88794.1 - 0.038 13.9 0.2 0.042 13.8 0.2 1.1 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Fzo_mitofusin PF04799.13 PRP88794.1 - 0.041 13.4 0.7 0.041 13.4 0.7 1.1 1 0 0 1 1 1 0 fzo-like conserved region IF-2B PF01008.17 PRP88794.1 - 0.076 12.2 1.5 0.084 12.1 1.5 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF883 PF05957.13 PRP88794.1 - 0.16 12.6 1.7 0.2 12.3 1.7 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 PRP88794.1 - 0.41 9.8 1.0 0.45 9.7 1.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein Peptidase_S8 PF00082.22 PRP88795.1 - 3e-33 115.4 0.0 4.7e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family BRCT_2 PF16589.5 PRP88796.1 - 6.4e-12 45.7 0.1 6e-11 42.6 0.0 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PRP88796.1 - 1.1e-08 35.4 0.2 6.6e-05 23.2 0.1 3.2 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Abhydrolase_2 PF02230.16 PRP88797.1 - 9.7e-46 156.3 0.0 1.2e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 PRP88797.1 - 2e-08 34.1 0.0 4.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 PRP88797.1 - 2.5e-06 26.9 0.0 0.46 9.7 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PRP88797.1 - 0.00011 21.8 0.0 0.053 13.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 PRP88797.1 - 0.00021 22.0 0.0 0.00027 21.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 PRP88797.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 PRP88797.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold VirJ PF06057.11 PRP88797.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Esterase_phd PF10503.9 PRP88797.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase P2X_receptor PF00864.19 PRP88798.1 - 4.6e-17 62.2 1.9 2.6e-09 36.7 0.0 2.7 2 1 1 3 3 3 2 ATP P2X receptor Med24_N PF11277.8 PRP88799.1 - 0.0091 14.1 0.0 0.0091 14.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal Pkinase PF00069.25 PRP88800.1 - 6.3e-60 202.8 0.1 9.9e-60 202.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88800.1 - 7e-45 153.3 0.2 1.2e-44 152.6 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 PRP88800.1 - 0.013 15.1 11.1 0.011 15.3 2.5 3.1 2 1 1 3 3 3 0 RIO1 family Kinase-like PF14531.6 PRP88800.1 - 0.022 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PRP88800.1 - 0.036 12.8 0.2 0.036 12.8 0.2 2.1 2 1 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 PRP88800.1 - 0.1 11.9 0.3 0.21 10.9 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GATA PF00320.27 PRP88800.1 - 7 6.4 6.7 18 5.1 6.7 1.7 1 0 0 1 1 1 0 GATA zinc finger Chorein_N PF12624.7 PRP88801.1 - 4.3e-18 65.5 0.6 4.3e-18 65.5 0.6 3.5 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 RA PF00788.23 PRP88801.1 - 0.039 14.6 0.3 10 6.8 0.1 4.0 4 0 0 4 4 4 0 Ras association (RalGDS/AF-6) domain Sec5 PF15469.6 PRP88801.1 - 0.054 13.3 1.0 0.28 11.0 0.1 2.6 2 0 0 2 2 2 0 Exocyst complex component Sec5 Cep57_MT_bd PF06657.13 PRP88801.1 - 3.8 8.0 18.3 5.7 7.5 0.0 5.1 5 0 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Pkinase_Tyr PF07714.17 PRP88802.1 - 8e-62 208.9 0.0 3.9e-61 206.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88802.1 - 2.1e-38 132.2 0.0 2.4e-37 128.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP88802.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP88802.1 - 0.0078 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP88802.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SKG6 PF08693.10 PRP88802.1 - 0.12 11.8 5.8 0.27 10.7 5.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ldi PF18566.1 PRP88802.1 - 0.44 10.0 4.1 0.77 9.2 4.1 1.3 1 0 0 1 1 1 0 Linalool dehydratase/isomerase LemA PF04011.12 PRP88803.1 - 0.095 12.6 0.1 0.19 11.5 0.1 1.6 1 1 1 2 2 2 0 LemA family Pkinase PF00069.25 PRP88804.1 - 4.6e-44 150.8 0.0 6.1e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88804.1 - 1.9e-21 76.6 0.0 2.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP88804.1 - 2.4e-05 24.4 0.0 3.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP88804.1 - 0.00019 20.9 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP88804.1 - 0.0071 15.2 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 PRP88805.1 - 3.6e-63 213.4 0.5 1.9e-61 207.8 0.1 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88805.1 - 7.7e-36 123.7 0.1 1.6e-35 122.7 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-binding PF00249.31 PRP88805.1 - 5.6e-07 29.6 0.3 5.6e-07 29.6 0.3 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PRP88805.1 - 2e-05 24.8 1.1 0.00021 21.4 0.1 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain APH PF01636.23 PRP88805.1 - 0.017 15.0 0.0 0.048 13.6 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tox-HDC PF15656.6 PRP88805.1 - 0.05 13.8 0.8 14 5.9 0.1 2.5 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature IZUMO PF15005.6 PRP88805.1 - 5.5 7.5 8.9 3.4 8.2 1.8 3.5 1 1 3 4 4 4 0 Izumo sperm-egg fusion, Ig domain-associated MMR_HSR1 PF01926.23 PRP88806.1 - 3.7e-15 56.0 0.0 6.8e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP88806.1 - 3.5e-08 33.5 0.0 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PRP88806.1 - 4.3e-05 23.1 0.0 0.056 13.0 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 PRP88806.1 - 0.00019 21.0 0.0 0.028 13.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 PRP88806.1 - 0.014 15.4 0.2 0.06 13.4 0.2 2.0 1 1 0 1 1 1 0 Dynamin family Septin PF00735.18 PRP88806.1 - 0.053 12.8 0.3 0.23 10.7 0.0 2.1 2 1 0 2 2 2 0 Septin AAA_22 PF13401.6 PRP88806.1 - 0.085 13.1 0.0 1.1 9.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain Carb_bind PF10645.9 PRP88807.1 - 2e-08 34.3 23.3 1.3e-07 31.7 17.8 3.5 2 1 1 3 3 3 2 Carbohydrate binding Glyco_hydro_16 PF00722.21 PRP88807.1 - 3.5e-06 26.6 0.0 6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4225 PF13988.6 PRP88807.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Pkinase PF00069.25 PRP88809.1 - 3.4e-72 243.0 0.0 5e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88809.1 - 1.4e-34 119.5 0.0 2.1e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP88809.1 - 8.8e-11 41.6 0.1 2.2e-07 30.5 0.0 2.4 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 PRP88809.1 - 4.8e-07 29.6 0.5 1e-06 28.5 0.5 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PRP88809.1 - 2.9e-05 23.5 0.4 5.3e-05 22.7 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.25 PRP88809.1 - 0.0003 20.7 0.1 2.5 8.2 0.0 3.9 3 1 0 3 3 2 2 PAS fold PAS_4 PF08448.10 PRP88809.1 - 0.0012 19.0 0.0 4.4 7.6 0.0 3.6 4 0 0 4 4 4 1 PAS fold PAS_9 PF13426.7 PRP88809.1 - 0.0016 18.7 0.0 0.13 12.5 0.0 3.6 3 1 0 3 3 3 1 PAS domain APH PF01636.23 PRP88809.1 - 0.0059 16.5 0.1 0.087 12.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PRP88809.1 - 0.015 14.3 0.3 0.023 13.6 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 PRP88809.1 - 0.026 14.0 0.1 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 PRP88809.1 - 0.03 13.1 0.0 0.057 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase U-box PF04564.15 PRP88809.1 - 0.052 13.7 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 U-box domain Got1 PF04178.12 PRP88810.1 - 3.9e-10 40.1 14.2 4.8e-10 39.9 14.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family AMPK1_CBM PF16561.5 PRP88811.1 - 1.5e-11 44.4 0.2 3.6e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase ATG16 PF08614.11 PRP88811.1 - 0.0066 16.7 23.2 0.0066 16.7 23.2 8.4 1 1 7 8 8 8 1 Autophagy protein 16 (ATG16) IP_trans PF02121.18 PRP88813.1 - 1e-94 316.8 3.3 1.4e-94 316.3 3.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein CK2S PF15011.6 PRP88813.1 - 0.0017 18.3 0.2 0.0052 16.7 0.2 1.8 1 1 1 2 2 2 1 Casein Kinase 2 substrate Isochorismatase PF00857.20 PRP88813.1 - 0.16 12.1 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Isochorismatase family Cor1 PF04803.12 PRP88814.1 - 0.13 12.5 5.1 0.058 13.6 2.0 1.9 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region Peptidase_C1 PF00112.23 PRP88815.1 - 2.9e-44 151.8 9.1 6.1e-44 150.7 9.1 1.5 1 0 0 1 1 1 1 Papain family cysteine protease RhoGEF PF00621.20 PRP88815.1 - 2.2e-41 142.1 2.4 4.8e-41 141.0 2.4 1.6 1 0 0 1 1 1 1 RhoGEF domain Inhibitor_I29 PF08246.12 PRP88815.1 - 1.1e-08 35.4 1.8 3.5e-08 33.7 1.8 2.0 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Propeptide_C1 PF08127.13 PRP88815.1 - 2.3e-05 24.2 0.1 5.5e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide CENP-F_N PF10481.9 PRP88815.1 - 0.037 13.7 5.8 1.4 8.5 1.7 2.4 2 0 0 2 2 2 0 Cenp-F N-terminal domain Peptidase_C1_2 PF03051.15 PRP88815.1 - 0.063 12.0 1.3 0.39 9.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase C1-like family GldM_N PF12081.8 PRP88815.1 - 0.13 12.3 2.1 0.13 12.4 0.5 1.7 2 0 0 2 2 2 0 GldM N-terminal domain Antimicrobial_7 PF08102.11 PRP88815.1 - 0.41 10.9 2.5 12 6.2 0.3 3.0 3 0 0 3 3 3 0 Scorpion antimicrobial peptide DUF1492 PF07374.11 PRP88815.1 - 0.62 10.3 3.0 2.3 8.4 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) PH_3 PF14593.6 PRP88816.1 - 0.065 13.4 0.1 0.61 10.2 0.0 2.3 2 0 0 2 2 2 0 PH domain Chitin_bind_1 PF00187.19 PRP88817.1 - 5.1e-07 30.1 22.4 5.1e-07 30.1 22.4 3.4 4 0 0 4 4 4 1 Chitin recognition protein Chalcone PF02431.15 PRP88818.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Chalcone-flavanone isomerase Pkinase PF00069.25 PRP88819.1 - 1.7e-13 50.6 0.0 2.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88819.1 - 3e-11 43.1 0.0 4.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase GPS PF01825.21 PRP88819.1 - 1.6e-09 38.1 7.3 1.6e-09 38.1 7.3 3.1 3 0 0 3 3 3 1 GPCR proteolysis site, GPS, motif 2OG-FeII_Oxy_2 PF13532.6 PRP88820.1 - 4.8e-27 95.4 0.0 9.3e-27 94.5 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_S10 PF00450.22 PRP88822.1 - 8.4e-122 407.6 1.9 1e-121 407.3 1.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_transf_20 PF00982.21 PRP88824.1 - 1.1e-177 591.5 0.0 1.3e-177 591.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PRP88824.1 - 2e-34 118.7 0.0 3.5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 PRP88824.1 - 0.00037 20.1 0.1 0.9 9.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 DUF3671 PF12420.8 PRP88825.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function zf-CCCH_6 PF18585.1 PRP88825.1 - 0.2 11.5 0.5 0.45 10.4 0.5 1.6 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 MDFI PF15316.6 PRP88825.1 - 1.2 9.2 2.9 2.9 8.0 2.9 1.6 1 0 0 1 1 1 0 MyoD family inhibitor Pkinase PF00069.25 PRP88827.1 - 3.2e-50 171.0 0.3 3.7e-36 124.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88827.1 - 1.3e-22 80.4 0.1 5.9e-14 52.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PRP88827.1 - 1.8e-07 30.7 0.0 3.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.7 PRP88827.1 - 0.00011 22.3 0.0 0.31 11.3 0.0 2.6 1 1 1 2 2 2 2 PAS domain Choline_kinase PF01633.20 PRP88827.1 - 0.0018 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase PAS PF00989.25 PRP88827.1 - 0.014 15.4 0.0 0.98 9.4 0.0 2.6 2 0 0 2 2 2 0 PAS fold Kdo PF06293.14 PRP88827.1 - 0.017 14.5 0.3 0.03 13.7 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP88827.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 PRP88827.1 - 0.033 13.8 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.7 PRP88828.1 - 3.7e-12 46.7 0.1 2.9e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP88828.1 - 5.8e-08 32.9 0.8 0.043 14.1 0.0 3.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP88828.1 - 2.5e-06 27.9 0.0 0.072 13.7 0.0 3.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP88828.1 - 0.00019 21.7 1.1 6.8 7.3 0.1 4.7 4 1 0 4 4 4 1 Ankyrin repeat Acetyltransf_8 PF13523.6 PRP88828.1 - 0.011 15.5 0.1 1.4 8.6 0.0 2.6 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Ank_3 PF13606.6 PRP88828.1 - 0.045 14.3 0.1 43 5.1 0.1 3.9 4 1 0 4 4 4 0 Ankyrin repeat Epimerase PF01370.21 PRP88829.1 - 2.1e-16 60.1 0.6 2.1e-15 56.8 0.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PRP88829.1 - 2.6e-12 47.0 0.4 3.7e-12 46.5 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PRP88829.1 - 5.1e-11 42.5 0.1 4.4e-07 29.6 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 PRP88829.1 - 9.8e-07 28.6 0.6 1.7e-06 27.8 0.6 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 PRP88829.1 - 2.4e-06 26.8 0.1 6.2e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PRP88829.1 - 1.1e-05 24.7 0.1 1.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 PRP88829.1 - 4.1e-05 22.8 0.6 0.00022 20.4 0.3 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.18 PRP88829.1 - 0.00074 19.8 0.2 0.0013 19.0 0.2 1.3 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 PRP88829.1 - 0.0019 17.7 0.1 0.005 16.3 0.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_2 PF03446.15 PRP88829.1 - 0.009 16.2 0.2 0.018 15.2 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_3 PF03447.16 PRP88829.1 - 0.037 14.7 0.3 0.067 13.9 0.3 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain KR PF08659.10 PRP88829.1 - 0.045 13.7 0.2 0.081 12.8 0.2 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 PRP88829.1 - 0.055 12.6 0.0 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 PRP88829.1 - 0.095 12.8 0.2 0.23 11.5 0.1 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Vitellogenin_N PF01347.22 PRP88829.1 - 0.19 10.1 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region IPPT PF01715.17 PRP88831.1 - 2.1e-49 168.4 0.0 4.3e-49 167.4 0.0 1.5 1 0 0 1 1 1 1 IPP transferase Glyco_transf_90 PF05686.12 PRP88831.1 - 1.4e-12 47.2 3.6 7.2e-08 31.7 2.8 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 90 IPT PF01745.16 PRP88831.1 - 0.0037 16.7 0.0 0.0084 15.5 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase AAA_PrkA PF08298.11 PRP88831.1 - 0.026 13.5 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain IgGFc_binding PF17517.2 PRP88831.1 - 0.037 13.3 0.3 0.087 12.1 0.0 1.7 2 0 0 2 2 2 0 IgGFc binding protein AAA_29 PF13555.6 PRP88831.1 - 0.11 12.3 0.3 0.32 10.7 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 PRP88831.1 - 0.15 11.1 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.14 PRP88831.1 - 0.15 12.0 0.1 0.69 9.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) zf-C3HC4_3 PF13920.6 PRP88832.1 - 8.7e-11 41.5 7.1 1.4e-10 40.8 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP88832.1 - 1.3e-08 35.0 10.3 3.1e-08 33.8 10.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PRP88832.1 - 1.4e-08 34.5 11.1 3e-08 33.4 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP88832.1 - 4e-07 29.8 8.2 7.9e-07 28.8 8.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 PRP88832.1 - 4.9e-07 29.9 6.0 1.1e-06 28.8 6.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PRP88832.1 - 1e-06 28.5 10.7 2.5e-06 27.2 10.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP88832.1 - 3.7e-06 26.9 4.7 5.3e-06 26.4 3.4 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PRP88832.1 - 7.5e-06 25.8 9.8 2.3e-05 24.2 9.9 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PRP88832.1 - 0.0056 16.7 1.5 0.011 15.8 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 PRP88832.1 - 0.0075 16.3 1.5 0.0075 16.3 1.5 2.1 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 PRP88832.1 - 0.0096 16.6 5.4 0.019 15.7 5.4 1.5 1 0 0 1 1 1 1 zinc-ribbon family zf-C3HC4_4 PF15227.6 PRP88832.1 - 0.012 15.8 8.2 0.081 13.1 8.6 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PRP88832.1 - 0.027 14.3 8.1 0.075 12.8 8.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 PRP88832.1 - 0.043 14.1 9.7 0.053 13.7 8.3 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 PRP88832.1 - 0.25 11.3 3.7 0.14 12.0 0.7 2.0 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 PRP88832.1 - 0.29 10.8 6.2 0.76 9.4 6.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 PRP88832.1 - 0.34 10.6 5.9 0.67 9.7 5.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger GAGA PF09237.11 PRP88832.1 - 1.8 8.4 4.8 2 8.3 2.1 2.3 2 0 0 2 2 2 0 GAGA factor PseudoU_synth_1 PF01416.20 PRP88833.1 - 3.5e-08 33.9 0.0 7.3e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF1676 PF07898.13 PRP88833.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF2340 PF10209.9 PRP88835.1 - 3.2e-48 163.1 0.4 4.9e-48 162.5 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Ubiquitin_4 PF18036.1 PRP88835.1 - 0.018 15.1 0.1 3.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Blt1 PF12754.7 PRP88835.1 - 0.037 14.4 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 Blt1 N-terminal domain DUF1828 PF08861.10 PRP88835.1 - 0.087 13.1 1.4 1.1 9.6 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function DUF1828 AAA_23 PF13476.6 PRP88836.1 - 3.6e-17 63.5 8.0 3.6e-17 63.5 8.0 4.2 3 1 1 4 4 3 1 AAA domain SMC_N PF02463.19 PRP88836.1 - 7.9e-16 58.2 0.0 2.8e-15 56.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Metallophos PF00149.28 PRP88836.1 - 1.5e-08 35.4 0.1 3.3e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PRP88836.1 - 2.5e-07 31.0 2.0 8e-07 29.4 0.3 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SbcCD_C PF13558.6 PRP88836.1 - 2.8e-05 24.3 0.2 9.2e-05 22.6 0.2 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 PRP88836.1 - 5.3e-05 23.1 4.8 5.3e-05 23.1 4.8 3.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 PRP88836.1 - 0.00034 20.3 0.0 0.00077 19.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PRP88836.1 - 0.00039 20.3 0.0 0.00039 20.3 0.0 2.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 PRP88836.1 - 0.0006 19.5 0.8 0.0032 17.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PRP88836.1 - 0.00064 19.9 0.0 0.006 16.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 PRP88836.1 - 0.044 14.3 0.2 0.044 14.3 0.2 4.5 3 2 0 3 3 3 0 ABC transporter Ndc1_Nup PF09531.10 PRP88836.1 - 1.4 7.6 16.5 0.36 9.4 11.4 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Ank_2 PF12796.7 PRP88837.1 - 2.9e-36 123.9 0.2 1.4e-11 44.8 0.0 4.3 1 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP88837.1 - 1.7e-34 117.8 0.3 1.5e-05 25.5 0.0 6.6 1 1 8 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 PRP88837.1 - 5.7e-15 55.2 1.7 1.4 9.3 0.0 7.8 2 1 6 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 PRP88837.1 - 8.7e-13 48.1 2.1 13 6.4 0.0 8.8 6 3 3 9 9 9 3 Ankyrin repeat Ank_3 PF13606.6 PRP88837.1 - 2.3e-12 45.9 0.1 3.1 8.6 0.0 8.6 8 1 1 9 9 9 2 Ankyrin repeat VWA_3_C PF18571.1 PRP88837.1 - 0.0001 22.1 5.0 1.3e+02 2.5 0.0 7.9 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain Birna_VP3 PF01767.16 PRP88837.1 - 0.00028 21.1 0.1 16 5.5 0.0 5.2 1 1 4 5 5 5 2 Birnavirus VP3 protein NUMOD3 PF07460.11 PRP88837.1 - 0.0035 17.5 0.0 69 3.8 0.0 4.8 5 0 0 5 5 5 0 NUMOD3 motif (2 copies) PRMT5_TIM PF17285.2 PRP88838.1 - 9.3e-73 244.6 0.3 1.4e-72 244.0 0.3 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 PRP88838.1 - 6.2e-66 221.5 0.0 9.7e-66 220.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 PRP88838.1 - 1.3e-56 191.3 6.1 2.6e-56 190.3 6.1 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain KdpC PF02669.15 PRP88839.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 K+-transporting ATPase, c chain EamA PF00892.20 PRP88840.1 - 3.2e-24 85.7 37.3 1e-17 64.6 16.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1129 PF06570.11 PRP88840.1 - 0.00027 20.5 2.9 0.00027 20.5 2.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) DUF2626 PF11117.8 PRP88840.1 - 8.1 7.2 10.4 2.3 9.0 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2626) DLH PF01738.18 PRP88841.1 - 5.6e-26 91.4 0.2 6.7e-26 91.2 0.2 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 PRP88841.1 - 0.0041 17.7 0.4 0.0072 16.9 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PRP88841.1 - 0.0051 16.5 0.1 0.42 10.2 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 PRP88841.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 PRP88841.1 - 0.03 14.2 0.1 1.7 8.5 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal BNR_assoc_N PF14873.6 PRP88842.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase Homeodomain PF00046.29 PRP88843.1 - 6.5e-16 57.9 7.2 1.9e-15 56.4 4.2 2.6 2 0 0 2 2 2 1 Homeodomain MRP-L20 PF12824.7 PRP88843.1 - 2.9e-05 24.3 1.5 5.4e-05 23.4 0.5 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.11 PRP88843.1 - 0.00071 19.4 3.9 0.0022 17.9 3.9 1.9 1 0 0 1 1 1 1 Homeobox KN domain Kelch_5 PF13854.6 PRP88844.1 - 1.8e-15 56.5 0.1 0.0037 17.2 0.0 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 PRP88844.1 - 2.6e-06 26.9 5.1 0.12 12.0 0.1 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 PRP88844.1 - 3.9e-06 26.8 1.2 8.3 6.5 0.0 5.5 4 1 1 5 5 5 3 Galactose oxidase, central domain zf-MYND PF01753.18 PRP88844.1 - 6.8e-06 26.1 10.4 1.9e-05 24.6 10.4 1.8 1 0 0 1 1 1 1 MYND finger Kelch_2 PF07646.15 PRP88844.1 - 3.1e-05 23.8 4.4 4 7.6 0.0 5.0 5 0 0 5 5 5 2 Kelch motif TPR_1 PF00515.28 PRP88844.1 - 0.00058 19.6 0.0 5.6 6.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP88844.1 - 0.003 17.5 2.5 1.2 9.4 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Kelch_6 PF13964.6 PRP88844.1 - 0.0053 17.0 5.3 1.2 9.6 0.0 5.5 7 0 0 7 7 7 1 Kelch motif TPR_16 PF13432.6 PRP88844.1 - 0.11 13.2 0.2 0.4 11.4 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FYVE PF01363.21 PRP88844.1 - 2.8 8.1 10.1 4.9 7.4 8.7 2.1 2 0 0 2 2 2 0 FYVE zinc finger CPSase_L_D2 PF02786.17 PRP88845.1 - 1.6e-78 263.1 0.1 2.7e-78 262.3 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PRP88845.1 - 3.7e-46 156.2 0.1 1.1e-45 154.7 0.1 1.9 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PRP88845.1 - 1.3e-35 121.7 0.0 2.9e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 PRP88845.1 - 6.1e-15 55.7 0.4 1.6e-14 54.4 0.4 1.7 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 PRP88845.1 - 6e-12 45.2 0.6 2e-11 43.5 0.6 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PRP88845.1 - 1.2e-08 34.8 0.0 2.8e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 PRP88845.1 - 6.7e-07 29.0 3.6 7.2e-06 25.7 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 PRP88845.1 - 3.8e-05 23.8 0.2 0.00011 22.3 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 PRP88845.1 - 0.0094 15.2 0.0 0.075 12.3 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 PRP88845.1 - 0.033 14.1 0.2 0.23 11.3 0.2 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein HlyD_3 PF13437.6 PRP88845.1 - 0.048 14.4 1.5 0.13 13.0 0.4 2.4 3 0 0 3 3 3 0 HlyD family secretion protein GARS_A PF01071.19 PRP88845.1 - 0.059 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AAA PF00004.29 PRP88846.1 - 4.8e-84 279.4 0.0 3.8e-42 143.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP88846.1 - 1e-26 92.4 0.5 6.7e-18 64.2 0.2 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 PRP88846.1 - 3.9e-11 43.6 0.1 0.00031 21.2 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 PRP88846.1 - 3.2e-10 40.2 0.1 0.00011 22.2 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PRP88846.1 - 1.2e-09 38.1 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PRP88846.1 - 4.1e-08 33.5 0.0 0.0045 17.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PRP88846.1 - 3.2e-07 29.9 1.7 0.0048 16.1 0.0 2.5 3 0 0 3 3 3 2 TIP49 P-loop domain Viral_helicase1 PF01443.18 PRP88846.1 - 3.2e-07 30.3 0.0 0.0043 16.8 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 PRP88846.1 - 5.7e-06 26.4 0.0 0.084 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PRP88846.1 - 6.3e-06 26.5 2.3 0.91 9.8 0.1 4.3 2 2 1 3 3 3 1 AAA domain AAA_3 PF07726.11 PRP88846.1 - 1.7e-05 24.7 0.0 0.22 11.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PRP88846.1 - 3.6e-05 24.0 0.0 0.28 11.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 PRP88846.1 - 0.00022 21.2 0.1 0.07 13.0 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain NTPase_1 PF03266.15 PRP88846.1 - 0.00047 20.1 0.8 0.92 9.4 0.1 3.5 2 1 1 3 3 3 1 NTPase AAA_18 PF13238.6 PRP88846.1 - 0.0011 19.5 0.1 0.044 14.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 PRP88846.1 - 0.0025 17.7 2.7 0.42 10.5 0.3 3.3 4 0 0 4 4 3 1 NACHT domain RNA_helicase PF00910.22 PRP88846.1 - 0.0031 17.9 0.0 0.84 10.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 PRP88846.1 - 0.0037 16.8 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_11 PF13086.6 PRP88846.1 - 0.0053 16.6 0.9 0.67 9.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 PRP88846.1 - 0.006 16.3 0.3 1.7 8.3 0.0 2.8 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_tran PF00005.27 PRP88846.1 - 0.0084 16.6 0.6 8.3 6.9 0.0 3.2 3 0 0 3 3 3 0 ABC transporter DUF815 PF05673.13 PRP88846.1 - 0.011 15.0 0.0 0.92 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 PRP88846.1 - 0.013 15.5 0.1 2.8 8.0 0.1 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 PRP88846.1 - 0.019 14.7 0.5 5.6 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 PRP88846.1 - 0.036 13.8 0.1 8 6.1 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 PRP88846.1 - 0.071 13.3 0.2 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain BRCT PF00533.26 PRP88846.1 - 0.097 13.1 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ATPase PF06745.13 PRP88846.1 - 0.12 11.7 4.9 6 6.1 0.2 3.5 3 1 1 4 4 4 0 KaiC AAA_29 PF13555.6 PRP88846.1 - 0.13 12.0 0.1 5.6 6.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 PRP88846.1 - 0.16 11.2 0.9 0.88 8.8 0.1 2.5 3 0 0 3 3 3 0 Zeta toxin Mg_chelatase PF01078.21 PRP88846.1 - 0.17 11.2 0.3 7.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 PRP88846.1 - 0.25 10.4 3.1 4.6 6.2 2.4 2.8 2 1 0 2 2 2 0 Type II/IV secretion system protein Pkinase_Tyr PF07714.17 PRP88848.1 - 1.7e-77 260.2 0.0 2.1e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88848.1 - 3.8e-49 167.4 0.0 5.4e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain OSTbeta PF15048.6 PRP88848.1 - 0.0059 16.7 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein TMEM154 PF15102.6 PRP88848.1 - 0.0069 16.3 0.2 0.018 15.0 0.2 1.6 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.6 PRP88848.1 - 0.013 16.3 0.2 0.03 15.2 0.2 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Kdo PF06293.14 PRP88848.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ArsP_1 PF03773.13 PRP88848.1 - 0.029 13.5 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 Predicted permease Pkinase_fungal PF17667.1 PRP88848.1 - 0.055 12.2 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pur_ac_phosph_N PF16656.5 PRP88848.1 - 0.091 13.3 0.1 8.1 7.1 0.0 2.9 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain DUF5129 PF17173.4 PRP88848.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Protocadherin PF08374.11 PRP88848.1 - 0.17 11.9 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Protocadherin NMT PF01233.19 PRP88849.1 - 7.2e-75 250.2 0.0 1.2e-74 249.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 PRP88849.1 - 2.4e-73 246.1 0.0 3.9e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain TRAM_LAG1_CLN8 PF03798.16 PRP88849.1 - 2e-40 138.7 24.1 2e-40 138.7 24.1 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 PRP88849.1 - 2.1e-15 56.1 0.1 2.1e-15 56.1 0.1 2.2 2 0 0 2 2 2 1 TRAM1-like protein Acetyltransf_9 PF13527.7 PRP88849.1 - 0.0025 17.9 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP88849.1 - 0.082 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Peptidase_C1 PF00112.23 PRP88850.1 - 1.4e-46 159.3 7.4 1.4e-46 159.3 7.4 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP88850.1 - 1.2e-09 38.4 4.1 2e-09 37.7 4.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Propeptide_C1 PF08127.13 PRP88850.1 - 2.4e-08 33.7 0.2 4.9e-08 32.7 0.2 1.5 1 0 0 1 1 1 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 PRP88850.1 - 0.076 11.8 1.6 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase C1-like family Pkinase PF00069.25 PRP88851.1 - 3.5e-49 167.5 0.0 6.2e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88851.1 - 1.1e-34 120.0 0.0 1.8e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase VWA_3 PF13768.6 PRP88851.1 - 7.6e-24 84.4 0.0 1.4e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP88851.1 - 2.3e-14 54.0 0.0 3.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PRP88851.1 - 1.6e-11 44.8 0.0 4.5e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.10 PRP88851.1 - 1.6e-09 37.9 0.0 3.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain PBD PF00786.28 PRP88851.1 - 1.1e-07 32.1 0.0 2.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain VIT_2 PF13757.6 PRP88851.1 - 0.00018 21.3 0.0 0.00043 20.1 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 PRP88851.1 - 0.024 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein PIN_4 PF13638.6 PRP88852.1 - 6.8e-22 78.2 0.4 6.8e-22 78.2 0.4 1.4 2 0 0 2 2 2 1 PIN domain PIN_9 PF18477.1 PRP88852.1 - 0.0015 18.8 0.3 0.014 15.7 0.3 2.1 1 1 0 1 1 1 1 PIN like domain PIN PF01850.21 PRP88852.1 - 0.014 15.9 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 PIN domain PIN_3 PF13470.6 PRP88852.1 - 0.019 15.7 0.5 0.055 14.2 0.5 1.8 1 1 0 1 1 1 0 PIN domain DUF4411 PF14367.6 PRP88852.1 - 0.13 12.2 0.1 0.35 10.7 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) RhoGAP PF00620.27 PRP88853.1 - 2.8e-40 137.6 0.0 2.8e-40 137.6 0.0 3.5 4 0 0 4 4 4 1 RhoGAP domain DUF2054 PF10218.9 PRP88854.1 - 1.4e-15 57.5 18.3 2.1e-15 57.0 18.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) CMD PF02627.20 PRP88855.1 - 2.8e-07 30.5 0.0 1.1e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Syndecan PF01034.20 PRP88856.1 - 0.31 11.0 1.4 0.72 9.8 1.4 1.5 1 0 0 1 1 1 0 Syndecan domain PSI PF01437.25 PRP88856.1 - 1.2 9.7 40.0 0.088 13.4 7.3 4.0 3 1 0 3 3 3 0 Plexin repeat G8 PF10162.9 PRP88857.1 - 2.3e-19 69.7 0.1 6.8e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 G8 domain Nop52 PF05997.12 PRP88857.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Beta_helix PF13229.6 PRP88857.1 - 0.45 10.4 14.1 0.048 13.5 0.9 4.2 4 1 0 4 4 4 0 Right handed beta helix region Ribosomal_S7e PF01251.18 PRP88858.1 - 4.5e-74 248.2 3.3 6.6e-74 247.6 3.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7e VPS13 PF16908.5 PRP88859.1 - 2.4e-64 217.4 7.0 9.3e-64 215.4 0.1 4.2 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 PRP88859.1 - 3e-58 197.3 11.1 3.3e-54 184.1 0.4 4.1 3 1 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 PRP88859.1 - 2.8e-57 193.3 8.6 1.3e-55 187.9 0.3 4.1 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 PRP88859.1 - 1.9e-44 151.9 31.3 4.3e-44 150.7 4.0 6.1 6 1 0 6 6 6 2 Repeating coiled region of VPS13 Chorein_N PF12624.7 PRP88859.1 - 3.3e-36 123.9 0.8 1.2e-34 118.9 0.1 3.2 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 WD40 PF00400.32 PRP88859.1 - 3.7e-28 97.2 27.8 1.3e-07 32.2 1.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ATG_C PF09333.11 PRP88859.1 - 2.3e-06 27.9 0.1 6.9e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ANAPC4_WD40 PF12894.7 PRP88859.1 - 3.1e-05 24.2 4.5 0.58 10.5 0.0 5.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain JHD PF17811.1 PRP88859.1 - 0.0074 16.8 0.5 0.12 13.0 0.0 3.0 2 0 0 2 2 2 1 Jumonji helical domain Gmad1 PF10647.9 PRP88859.1 - 0.025 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain LisH_TPL PF17814.1 PRP88859.1 - 0.62 9.8 4.8 0.14 11.8 0.1 2.3 2 0 0 2 2 2 0 LisH-like dimerisation domain Trypsin_2 PF13365.6 PRP88860.1 - 1.2e-24 87.9 0.0 1.3e-16 61.8 0.0 2.4 2 1 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 PRP88860.1 - 0.00011 22.1 0.0 0.0017 18.2 0.0 2.4 2 0 0 2 2 2 1 Trypsin DUF31 PF01732.16 PRP88860.1 - 0.047 13.2 0.6 0.63 9.5 0.1 2.2 1 1 1 2 2 2 0 Putative peptidase (DUF31) adh_short PF00106.25 PRP88861.1 - 2.7e-17 62.9 0.1 3e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP88861.1 - 3.6e-13 49.6 0.1 4e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP88861.1 - 9.3e-06 25.7 0.0 1.1e-05 25.4 0.0 1.0 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP88861.1 - 3.2e-05 23.9 0.3 3.6e-05 23.7 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 PRP88862.1 - 2.4e-08 33.8 0.0 3.2e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP88862.1 - 1.3e-06 28.0 0.0 1.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase EF-hand_5 PF13202.6 PRP88863.1 - 6.2e-10 38.1 19.8 0.67 9.6 0.2 6.3 6 0 0 6 6 6 6 EF hand EF-hand_1 PF00036.32 PRP88863.1 - 4.8e-09 35.1 14.3 2.1 8.1 0.1 6.3 6 0 0 6 6 6 6 EF hand Dockerin_1 PF00404.18 PRP88863.1 - 1.9e-08 34.4 9.1 3.6 7.9 0.0 6.1 6 0 0 6 6 6 3 Dockerin type I domain EF-hand_7 PF13499.6 PRP88863.1 - 2.1e-08 34.5 11.6 5.8 7.4 0.0 6.3 6 0 0 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 PRP88863.1 - 1.8e-07 30.5 17.2 3.2 7.9 0.1 6.4 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.6 PRP88863.1 - 0.00043 20.1 5.1 21 5.0 0.0 6.0 6 0 0 6 6 6 1 EF-hand domain pair Excalibur PF05901.11 PRP88863.1 - 3.5 8.3 11.8 3.2e+02 2.0 0.2 6.1 6 1 0 6 6 6 0 Excalibur calcium-binding domain PAP_assoc PF03828.19 PRP88864.1 - 8.1e-21 74.0 0.3 4.1e-20 71.7 0.3 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase Peptidase_M4_C PF02868.15 PRP88864.1 - 9.8e-19 67.8 0.0 2.2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 PRP88864.1 - 0.004 17.7 0.0 0.0072 16.8 0.0 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain NTP_transf_2 PF01909.23 PRP88864.1 - 0.005 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain zf-TRAF PF02176.18 PRP88865.1 - 4.5e-05 24.1 1.7 6.6e-05 23.5 0.3 1.9 1 1 1 2 2 2 1 TRAF-type zinc finger zf-TRAF_2 PF15965.5 PRP88865.1 - 0.00028 21.3 0.6 0.00038 20.9 0.6 1.3 1 0 0 1 1 1 1 TRAF-like zinc-finger Pellino PF04710.14 PRP88865.1 - 0.046 12.4 0.4 0.048 12.3 0.4 1.0 1 0 0 1 1 1 0 Pellino End_beta_propel PF12217.8 PRP88865.1 - 0.059 12.0 0.0 0.061 12.0 0.0 1.0 1 0 0 1 1 1 0 Catalytic beta propeller domain of bacteriophage endosialidase PhoLip_ATPase_C PF16212.5 PRP88866.1 - 1.3e-73 247.8 25.2 1.3e-73 247.8 25.2 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PRP88866.1 - 5.9e-25 86.8 4.1 5.9e-25 86.8 4.1 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PRP88866.1 - 9.8e-14 52.1 0.1 4.9e-05 23.7 0.0 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP88866.1 - 3.3e-12 46.3 0.0 4e-11 42.8 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 PRP88866.1 - 4.2e-08 32.9 0.0 4.2e-08 32.9 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase zf-RING_UBOX PF13445.6 PRP88866.1 - 0.00084 19.3 12.8 0.0026 17.7 12.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Hydrolase_3 PF08282.12 PRP88866.1 - 0.0012 18.7 0.2 0.0084 15.9 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 PRP88866.1 - 0.0025 18.1 13.3 0.01 16.2 13.3 2.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PRP88866.1 - 0.0035 17.1 14.9 0.0035 17.1 14.9 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PRP88866.1 - 0.019 15.1 13.4 0.084 13.0 13.4 2.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PRP88866.1 - 0.026 14.5 11.4 0.08 12.9 11.4 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_10 PF16685.5 PRP88866.1 - 8.7 6.6 12.6 43 4.3 12.6 2.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 RNase_P_Rpp14 PF01900.19 PRP88867.1 - 3.2e-05 24.1 0.0 5.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Rpp14/Pop5 family GHMP_kinases_N PF00288.26 PRP88868.1 - 2.7e-15 56.3 0.4 6e-15 55.2 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PRP88868.1 - 2.6e-06 27.7 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Ank_4 PF13637.6 PRP88869.1 - 0.022 15.4 2.6 6.5 7.5 0.0 4.7 5 2 1 6 6 6 0 Ankyrin repeats (many copies) DUF5615 PF18480.1 PRP88869.1 - 0.043 13.6 0.2 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5615) Mob1_phocein PF03637.17 PRP88870.1 - 7e-38 130.3 4.2 4e-37 127.8 4.2 2.0 1 1 0 1 1 1 1 Mob1/phocein family tify PF06200.14 PRP88871.1 - 0.14 11.5 0.1 0.3 10.4 0.1 1.6 1 0 0 1 1 1 0 tify domain HABP4_PAI-RBP1 PF04774.15 PRP88872.1 - 7.5e-16 59.0 5.5 7.5e-16 59.0 5.5 3.2 3 1 0 3 3 3 1 Hyaluronan / mRNA binding family TMEM214 PF10151.9 PRP88872.1 - 0.08 11.4 0.8 0.12 10.8 0.8 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF1805 PF08827.11 PRP88872.1 - 0.1 12.9 0.1 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) SNAPc19 PF15497.6 PRP88873.1 - 0.0023 18.4 3.1 0.0023 18.4 3.1 2.7 2 1 0 2 2 2 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 VGLL4 PF15245.6 PRP88873.1 - 3.9 7.5 10.5 0.1 12.6 0.5 2.5 2 1 1 3 3 3 0 Transcription cofactor vestigial-like protein 4 WD40 PF00400.32 PRP88874.1 - 4.3e-16 59.0 8.7 1.4e-05 25.7 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Homeodomain PF00046.29 PRP88874.1 - 1.4e-13 50.4 5.3 7.3e-13 48.2 3.6 2.3 2 0 0 2 2 2 1 Homeodomain ANAPC4_WD40 PF12894.7 PRP88874.1 - 3.5e-05 24.0 0.3 4 7.8 0.0 5.5 5 2 0 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Homeobox_KN PF05920.11 PRP88874.1 - 0.0002 21.2 1.4 0.00076 19.3 1.4 2.0 1 0 0 1 1 1 1 Homeobox KN domain Nup160 PF11715.8 PRP88874.1 - 0.00089 18.0 0.1 0.28 9.8 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PRP88874.1 - 0.0013 17.8 0.1 0.0099 14.9 0.1 2.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HOCHOB PF17943.1 PRP88874.1 - 0.056 14.1 0.4 0.13 13.0 0.4 1.5 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox AAA_11 PF13086.6 PRP88875.1 - 2e-69 234.3 0.1 2e-69 234.3 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 PRP88875.1 - 2e-58 197.3 0.0 5.8e-58 195.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP88875.1 - 1.8e-09 38.1 0.0 5.9e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PRP88875.1 - 2.9e-08 33.7 0.0 5.6e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 PRP88875.1 - 5.3e-06 26.3 0.1 0.022 14.5 0.0 3.7 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 PRP88875.1 - 0.0064 16.8 0.2 1.2 9.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain ResIII PF04851.15 PRP88875.1 - 0.058 13.4 0.0 0.29 11.1 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 PRP88875.1 - 0.077 13.4 0.0 0.3 11.4 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 PRP88875.1 - 0.078 13.0 0.0 0.3 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PRP88875.1 - 0.12 12.8 0.1 0.83 10.1 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 PRP88876.1 - 1e-51 175.9 0.0 1.2e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88876.1 - 5.5e-26 91.4 0.0 8.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP88876.1 - 2.5e-06 26.6 0.0 3.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP88876.1 - 7.7e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 PRP88876.1 - 0.003 17.2 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PRP88876.1 - 0.0077 16.2 0.1 0.4 10.6 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family TetR_C_31 PF17940.1 PRP88876.1 - 0.012 15.8 0.1 0.059 13.6 0.0 2.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Seadorna_VP7 PF07387.11 PRP88876.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 BTB PF00651.31 PRP88877.1 - 9.1e-16 58.1 0.2 7.8e-15 55.1 0.1 2.3 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 PRP88877.1 - 1.4e-08 34.7 0.5 1.6e-07 31.4 0.3 2.6 2 1 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 PRP88877.1 - 4.3e-05 23.6 0.1 8.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 PRP88877.1 - 0.0035 17.4 0.0 0.026 14.5 0.0 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal DUF4394 PF14339.6 PRP88878.1 - 8.8e-21 74.3 1.5 8.8e-21 74.3 1.5 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4394) INCENP_ARK-bind PF03941.15 PRP88880.1 - 0.11 12.4 0.8 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Abhydrolase_3 PF07859.13 PRP88881.1 - 2e-29 103.0 0.0 3.3e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 PRP88881.1 - 1.2e-16 60.6 0.0 4.7e-16 58.6 0.0 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF3089 PF11288.8 PRP88881.1 - 0.032 13.8 0.1 6.2 6.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3089) DUF2974 PF11187.8 PRP88881.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) COesterase PF00135.28 PRP88881.1 - 0.12 11.2 0.0 1.6 7.5 0.0 2.0 1 1 0 1 1 1 0 Carboxylesterase family DNA_ligase_A_C PF04679.15 PRP88882.1 - 0.024 15.2 0.0 0.1 13.2 0.0 2.1 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region Ndc1_Nup PF09531.10 PRP88882.1 - 0.03 13.0 0.7 0.046 12.4 0.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UL42 PF17638.2 PRP88882.1 - 3.2 7.7 5.9 6.1 6.8 5.0 1.8 2 0 0 2 2 2 0 HCMV UL42 GST_N_3 PF13417.6 PRP88883.1 - 4.9e-18 65.3 0.2 5.9e-09 36.2 0.0 2.6 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PRP88883.1 - 1.6e-08 34.6 0.0 0.0066 16.7 0.0 2.3 2 0 0 2 2 2 2 Glutaredoxin GST_N_2 PF13409.6 PRP88883.1 - 5.2e-05 23.5 0.1 0.062 13.6 0.0 2.9 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain CBS PF00571.28 PRP88884.1 - 3.5e-31 107.4 6.2 1.1e-07 32.2 0.0 4.3 4 0 0 4 4 4 4 CBS domain Homeodomain PF00046.29 PRP88885.1 - 8.5e-16 57.5 3.9 1.5e-15 56.7 3.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP88885.1 - 2.1e-07 30.7 0.5 2.1e-07 30.7 0.5 1.8 2 0 0 2 2 2 1 Homeobox KN domain Remorin_C PF03763.13 PRP88885.1 - 0.02 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region Leo1 PF04004.13 PRP88886.1 - 7.5e-40 136.5 0.4 7.5e-40 136.5 0.4 3.1 2 2 0 2 2 2 1 Leo1-like protein CBM-like PF14683.6 PRP88886.1 - 0.11 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III Dsh_C PF12316.8 PRP88886.1 - 3.2 8.1 12.3 0.18 12.2 6.2 1.9 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF1748 PF08520.10 PRP88887.1 - 0.038 13.9 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) dUTPase PF00692.19 PRP88888.1 - 6.3e-06 25.9 0.0 9.9e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 dUTPase KASH_CCD PF14662.6 PRP88888.1 - 0.036 13.9 49.9 0.1 12.4 21.8 3.4 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH NPV_P10 PF05531.12 PRP88888.1 - 4 8.0 11.1 10 6.7 8.4 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PRP38 PF03371.15 PRP88890.1 - 1.4e-44 152.1 0.2 1.9e-44 151.6 0.2 1.2 1 0 0 1 1 1 1 PRP38 family SRP-alpha_N PF04086.13 PRP88890.1 - 2.1 8.2 12.3 3.6 7.4 12.3 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Herpes_heli_pri PF05774.11 PRP88892.1 - 0.03 14.5 0.1 0.078 13.2 0.1 1.6 1 1 1 2 2 2 0 Herpesvirus helicase-primase complex component DUF2974 PF11187.8 PRP88893.1 - 3e-07 30.2 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 PRP88893.1 - 0.00011 22.0 0.4 0.0015 18.4 0.1 2.5 2 1 0 2 2 2 1 Lipase (class 3) RsgA_GTPase PF03193.16 PRP88893.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 PRP88893.1 - 0.0023 18.0 0.0 0.0054 16.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF676 PF05057.14 PRP88893.1 - 0.0026 17.3 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 PRP88893.1 - 0.0032 18.1 0.4 0.59 10.7 0.2 3.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 PRP88893.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 PRP88893.1 - 0.015 15.0 0.3 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 PRP88893.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.25 PRP88894.1 - 1.2e-20 73.8 0.6 2e-20 73.1 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP88894.1 - 1.2e-13 51.2 0.2 1.6e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PRP88894.1 - 8.9e-06 25.3 0.3 6.2e-05 22.6 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PRP88894.1 - 0.0015 17.6 0.4 0.0021 17.1 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PRP88894.1 - 0.015 15.2 1.6 0.021 14.7 1.6 1.3 1 1 0 1 1 1 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 PRP88894.1 - 0.041 13.0 0.4 0.078 12.1 0.1 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain IpaB_EvcA PF03278.13 PRP88894.1 - 0.056 13.2 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 IpaB/EvcA family TrkA_N PF02254.18 PRP88894.1 - 0.079 13.2 0.5 0.14 12.4 0.5 1.4 1 0 0 1 1 1 0 TrkA-N domain GST_N_3 PF13417.6 PRP88895.1 - 8.2e-11 42.2 0.0 2.9e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP88895.1 - 2e-06 27.7 0.1 3.2e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PRP88895.1 - 3e-06 27.5 0.0 5.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP88895.1 - 5.5e-05 23.3 0.1 0.00015 21.9 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP88895.1 - 0.0035 17.5 0.0 0.0073 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF760 PF05542.11 PRP88895.1 - 0.04 14.3 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF760) DEAD PF00270.29 PRP88897.1 - 4.3e-44 150.4 0.5 8.8e-44 149.4 0.5 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP88897.1 - 3.1e-28 98.3 0.1 4.8e-27 94.5 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GTP_EFTU PF00009.27 PRP88898.1 - 3e-28 98.7 3.1 9.2e-27 93.8 3.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PRP88898.1 - 3.2e-22 78.6 0.8 1.8e-21 76.2 0.1 2.6 3 0 0 3 3 3 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 PRP88898.1 - 2.6e-10 40.4 0.2 9.9e-10 38.5 0.2 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP88898.1 - 5.8e-08 32.4 0.2 1.3e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.6 PRP88898.1 - 1.8e-05 24.6 5.4 5.9e-05 22.9 0.3 3.0 3 0 0 3 3 3 1 Elongation factor Tu domain 4 Ras PF00071.22 PRP88898.1 - 3.4e-05 23.5 0.1 9.7e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88898.1 - 0.0012 19.0 0.0 0.0032 17.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP88898.1 - 0.0013 18.2 0.1 0.0036 16.8 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PRP88898.1 - 0.013 15.4 1.0 0.5 10.3 0.2 2.5 1 1 1 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 PRP88898.1 - 0.02 15.0 0.1 1.9 8.5 0.0 2.8 1 1 1 2 2 2 0 Dynamin family PduV-EutP PF10662.9 PRP88898.1 - 0.027 14.2 0.3 0.099 12.4 0.3 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 PRP88898.1 - 0.03 14.3 0.5 0.1 12.6 0.4 2.0 2 0 0 2 2 1 0 C-terminal region of MMR_HSR1 domain Homeodomain PF00046.29 PRP88900.1 - 1.4e-15 56.9 5.5 2.7e-15 55.9 5.5 1.5 1 0 0 1 1 1 1 Homeodomain Abhydrolase_6 PF12697.7 PRP88900.1 - 2.1e-08 35.1 0.0 4.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Homeobox_KN PF05920.11 PRP88900.1 - 0.0043 16.9 0.4 0.0089 15.9 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain Abhydrolase_8 PF06259.12 PRP88900.1 - 0.016 14.9 0.1 0.042 13.5 0.2 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase PAC1 PF16094.5 PRP88900.1 - 0.084 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Glyco_hydro_16 PF00722.21 PRP88901.1 - 1.1e-23 83.6 0.1 1.1e-23 83.6 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 X8 PF07983.13 PRP88901.1 - 7.5e-15 55.4 12.7 1.3e-07 32.2 5.0 3.0 3 0 0 3 3 3 2 X8 domain STAS PF01740.21 PRP88901.1 - 0.016 14.9 0.2 0.03 13.9 0.2 1.4 1 0 0 1 1 1 0 STAS domain DUF3894 PF13033.6 PRP88901.1 - 0.033 14.3 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3894) DUF4698 PF15769.5 PRP88901.1 - 2.5 7.0 6.5 3.8 6.5 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) PIG-S PF10510.9 PRP88902.1 - 3.6e-98 329.6 0.5 4.5e-98 329.3 0.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein PI-TkoII_IV PF18714.1 PRP88902.1 - 0.023 14.2 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV NIF PF03031.18 PRP88902.1 - 0.053 13.3 0.2 0.5 10.1 0.1 2.5 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase G8 PF10162.9 PRP88903.1 - 9.8e-22 77.3 0.6 2.3e-21 76.2 0.6 1.6 1 0 0 1 1 1 1 G8 domain X8 PF07983.13 PRP88903.1 - 9.2e-09 35.9 0.9 2e-08 34.8 0.9 1.6 1 0 0 1 1 1 1 X8 domain Beta_helix PF13229.6 PRP88903.1 - 5.4e-05 23.1 2.3 0.00026 20.8 0.4 3.0 2 1 0 2 2 2 1 Right handed beta helix region Trypan_PARP PF05887.11 PRP88903.1 - 4.2 7.4 14.3 0.73 9.8 8.5 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Arf PF00025.21 PRP88904.1 - 1.1e-66 223.6 0.2 1.2e-66 223.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP88904.1 - 3.2e-13 49.6 0.0 3.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 PRP88904.1 - 1.7e-12 47.2 0.0 1.9e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP88904.1 - 2.7e-12 47.0 0.0 3.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PRP88904.1 - 2e-09 37.1 0.0 2.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PRP88904.1 - 9.7e-09 34.8 0.1 1.8e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PRP88904.1 - 3.1e-06 27.3 0.0 6.2e-06 26.3 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 PRP88904.1 - 0.0018 17.3 0.0 0.0035 16.4 0.0 1.3 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 PRP88904.1 - 0.11 12.1 0.3 0.5 9.9 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Med14 PF08638.11 PRP88904.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit MED14 IFT43 PF15305.6 PRP88905.1 - 7.9e-19 68.2 2.8 8.1e-19 68.1 2.1 1.4 1 1 0 1 1 1 1 Intraflagellar transport protein 43 DSPc PF00782.20 PRP88906.1 - 1.6e-23 83.0 0.0 2.6e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain EGF_CA PF07645.15 PRP88906.1 - 4.4e-12 46.0 17.4 3.2e-08 33.6 5.4 7.9 6 2 3 9 9 9 2 Calcium-binding EGF domain Y_phosphatase PF00102.27 PRP88906.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase EGF_2 PF07974.13 PRP88906.1 - 0.029 14.7 6.2 0.029 14.7 6.2 10.3 8 2 1 9 9 9 0 EGF-like domain Homeodomain PF00046.29 PRP88907.1 - 3e-16 59.0 1.1 7.7e-16 57.7 1.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP88907.1 - 4e-07 29.8 0.6 1.3e-06 28.2 0.6 1.9 1 0 0 1 1 1 1 Homeobox KN domain DHR-2 PF06920.13 PRP88908.1 - 9.1e-57 192.9 1.6 2.1e-56 191.7 1.6 1.5 1 1 0 1 1 1 1 Dock homology region 2 F-box-like PF12937.7 PRP88908.1 - 0.00016 21.5 0.2 0.00031 20.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP88908.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 F-box domain IQ PF00612.27 PRP88908.1 - 1.5 8.8 3.5 3.6 7.6 3.5 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pkinase PF00069.25 PRP88909.1 - 5.5e-77 258.7 0.0 7.9e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88909.1 - 2.7e-37 128.5 0.0 3.8e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 PRP88909.1 - 1.6e-19 70.1 0.2 2.7e-19 69.4 0.2 1.4 1 0 0 1 1 1 1 C2 domain Kdo PF06293.14 PRP88909.1 - 9.3e-05 21.9 0.2 0.00025 20.5 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP88909.1 - 0.0069 15.7 0.0 0.021 14.2 0.0 1.8 1 1 0 1 1 1 1 Kinase-like DUF4144 PF13642.6 PRP88909.1 - 0.066 13.8 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 protein structure with unknown function FTA2 PF13095.6 PRP88909.1 - 0.085 12.5 0.1 0.22 11.1 0.1 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Spherulin4 PF12138.8 PRP88910.1 - 1.8e-23 83.4 0.1 3.8e-23 82.4 0.0 1.5 2 0 0 2 2 2 1 Spherulation-specific family 4 SET PF00856.28 PRP88911.1 - 9.6e-08 32.6 0.3 2.1e-07 31.5 0.3 2.0 1 1 0 1 1 1 1 SET domain preSET_CXC PF18264.1 PRP88911.1 - 0.97 10.0 18.7 3 8.4 18.7 1.9 1 0 0 1 1 1 0 CXC domain Pkinase_Tyr PF07714.17 PRP88912.1 - 9.9e-26 90.6 0.2 1.5e-25 90.0 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88912.1 - 3e-19 69.4 0.1 4.9e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 PRP88912.1 - 0.015 14.7 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 PRP88913.1 - 6.8e-10 39.3 0.1 0.0002 21.7 0.0 4.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PRP88913.1 - 3.8e-09 35.7 0.1 0.22 11.5 0.0 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 PRP88913.1 - 1e-07 31.0 0.0 0.35 10.5 0.2 4.7 4 0 0 4 4 4 2 EF hand GUCT PF08152.12 PRP88913.1 - 0.11 12.8 0.3 0.31 11.3 0.3 1.8 1 0 0 1 1 1 0 GUCT (NUC152) domain DUF4530 PF15039.6 PRP88913.1 - 0.21 11.7 2.7 3.7 7.7 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) JIP_LZII PF16471.5 PRP88913.1 - 0.26 11.5 7.8 6 7.1 5.5 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II YabA PF06156.13 PRP88913.1 - 0.35 11.5 5.9 1.5 9.5 5.7 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 PRP88913.1 - 0.57 10.4 7.6 0.48 10.7 3.8 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Glyco_hydro_16 PF00722.21 PRP88914.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 Fic PF02661.18 PRP88915.1 - 2.6e-18 66.7 0.0 7.1e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family RINGv PF12906.7 PRP88916.1 - 2.9e-09 36.9 10.3 6.3e-09 35.8 10.3 1.6 1 0 0 1 1 1 1 RING-variant domain Zf_RING PF16744.5 PRP88916.1 - 0.11 12.7 6.7 0.12 12.5 4.5 2.1 1 1 1 2 2 2 0 KIAA1045 RING finger FANCL_C PF11793.8 PRP88916.1 - 0.19 11.9 3.7 0.37 11.0 3.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 PRP88916.1 - 2.5 8.1 8.5 11 6.0 8.6 2.1 1 1 1 2 2 2 0 PHD-finger Pkinase_Tyr PF07714.17 PRP88917.1 - 6.8e-49 166.5 0.0 1.3e-48 165.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88917.1 - 3.1e-40 138.2 0.0 1.4e-39 136.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain RasGEF PF00617.19 PRP88917.1 - 4.7e-40 137.7 0.2 1.5e-39 136.0 0.2 1.9 1 0 0 1 1 1 1 RasGEF domain COR PF16095.5 PRP88917.1 - 5.2e-25 88.4 0.0 1e-24 87.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain cNMP_binding PF00027.29 PRP88917.1 - 1.8e-20 72.8 0.5 1.7e-09 37.7 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Roc PF08477.13 PRP88917.1 - 5.9e-19 68.5 0.1 1.3e-18 67.3 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 PRP88917.1 - 1.8e-14 53.2 17.7 2e-08 33.8 5.1 2.8 2 0 0 2 2 2 2 Leucine rich repeat GRAM PF02893.20 PRP88917.1 - 2.4e-12 46.7 0.1 6.4e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 GRAM domain RasGEF_N PF00618.20 PRP88917.1 - 5.3e-12 45.9 0.0 1.9e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif LRR_4 PF12799.7 PRP88917.1 - 7.9e-12 45.2 23.4 3.6e-06 27.2 3.7 4.3 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) Ras PF00071.22 PRP88917.1 - 4.4e-08 32.9 0.0 9e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Ras family Arf PF00025.21 PRP88917.1 - 0.0022 17.4 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 PRP88917.1 - 0.0062 15.7 0.1 0.02 14.0 0.1 1.8 1 0 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.27 PRP88917.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain rve PF00665.26 PRP88917.1 - 0.14 12.3 0.0 0.6 10.3 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain PAH PF02671.21 PRP88917.1 - 0.16 12.1 0.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat LRR_1 PF00560.33 PRP88917.1 - 5.8 7.9 23.0 16 6.5 0.0 6.5 6 0 0 6 6 5 0 Leucine Rich Repeat Enkurin PF13864.6 PRP88917.1 - 9.9 6.7 7.8 15 6.1 3.2 2.9 2 0 0 2 2 2 0 Calmodulin-binding GAS PF13851.6 PRP88918.1 - 0.00095 18.6 6.5 0.0017 17.7 6.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Bap31 PF05529.12 PRP88918.1 - 0.00098 19.0 1.6 0.001 19.0 0.1 1.8 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region GCN5L1 PF06320.13 PRP88918.1 - 0.012 15.8 2.3 0.025 14.7 2.3 1.5 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF29 PF01724.16 PRP88918.1 - 0.016 15.4 1.3 0.03 14.6 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF29 Bap31_Bap29_C PF18035.1 PRP88918.1 - 0.016 15.2 16.8 0.72 9.9 0.8 2.5 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Macoilin PF09726.9 PRP88918.1 - 0.021 13.4 3.6 0.024 13.2 3.6 1.1 1 0 0 1 1 1 0 Macoilin family CCDC-167 PF15188.6 PRP88918.1 - 0.043 14.2 3.6 0.079 13.3 3.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4337 PF14235.6 PRP88918.1 - 0.073 13.2 2.8 0.14 12.2 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GAT PF03127.14 PRP88918.1 - 0.14 12.5 4.6 0.1 12.9 2.4 2.0 2 0 0 2 2 2 0 GAT domain APG6_N PF17675.1 PRP88918.1 - 0.19 12.3 9.4 0.29 11.7 9.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3734 PF12536.8 PRP88918.1 - 0.26 11.6 2.2 0.45 10.9 1.4 1.8 1 1 1 2 2 2 0 Patatin phospholipase DivIC PF04977.15 PRP88918.1 - 1.5 8.6 6.9 1.6 8.5 5.3 1.8 1 1 0 1 1 1 0 Septum formation initiator NEMO PF11577.8 PRP88918.1 - 2.4 8.2 9.6 0.28 11.2 1.4 2.8 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO YabA PF06156.13 PRP88918.1 - 6.9 7.4 8.6 2.7 8.7 4.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA VPS9 PF02204.18 PRP88919.1 - 1e-20 73.9 0.1 2e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PH PF00169.29 PRP88919.1 - 0.014 15.9 0.1 0.17 12.4 0.1 2.6 1 1 0 1 1 1 0 PH domain zf-WRNIP1_ubi PF18279.1 PRP88919.1 - 0.055 14.1 2.0 0.15 12.8 2.0 1.8 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF2052 PF09747.9 PRP88919.1 - 0.15 12.2 19.7 0.062 13.4 15.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CobT PF06213.12 PRP88919.1 - 3.4 7.0 23.1 6.8 6.0 23.1 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CPSF100_C PF13299.6 PRP88919.1 - 3.8 7.7 13.6 12 6.0 13.6 2.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Coilin_N PF15862.5 PRP88919.1 - 5.8 6.7 18.7 17 5.2 18.7 1.8 1 0 0 1 1 1 0 Coilin N-terminus RNA_polI_A34 PF08208.11 PRP88919.1 - 8.8 6.4 36.9 21 5.1 36.9 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Pkinase PF00069.25 PRP88920.1 - 1.6e-63 214.6 0.1 1.9e-63 214.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88920.1 - 4.7e-30 104.7 0.0 6.4e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP88920.1 - 2e-06 27.9 0.0 0.002 18.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP88920.1 - 0.00074 18.9 0.1 0.0014 18.0 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP88920.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 PRP88920.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 PRP88920.1 - 0.0025 16.8 0.7 0.0073 15.3 0.6 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Pantoate_ligase PF02569.15 PRP88923.1 - 4.7e-99 330.9 0.1 5.3e-99 330.8 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase COMM_domain PF07258.14 PRP88925.1 - 5.4e-15 55.3 0.1 9.8e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 COMM domain Ank_2 PF12796.7 PRP88926.1 - 0.00059 20.4 1.3 0.79 10.4 0.0 3.1 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) DUF2067 PF09840.9 PRP88926.1 - 0.014 15.0 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) Cas9_Topo PF17894.1 PRP88926.1 - 0.1 12.7 0.2 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 CPT_N PF16484.5 PRP88926.1 - 0.11 12.5 0.3 10 6.2 0.0 3.4 3 0 0 3 3 3 0 Carnitine O-palmitoyltransferase N-terminus DEAD PF00270.29 PRP88927.1 - 4.6e-39 134.0 0.8 5.1e-38 130.6 0.8 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP88927.1 - 8e-31 106.7 0.2 3e-30 104.8 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AATF-Che1 PF13339.6 PRP88928.1 - 2.1e-18 67.3 4.4 2.1e-18 67.3 4.4 3.3 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 PRP88928.1 - 0.0046 17.4 0.2 0.0046 17.4 0.2 2.7 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal IF4E PF01652.18 PRP88929.1 - 5.9e-56 188.7 1.2 7.3e-56 188.4 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cmc1 PF08583.10 PRP88930.1 - 1.1e-10 41.3 0.2 1.7e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like BppL_N PF18338.1 PRP88930.1 - 0.11 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain UAA PF08449.11 PRP88931.1 - 5.6e-69 232.6 18.8 3.1e-38 131.7 6.6 2.1 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.20 PRP88931.1 - 6.8e-13 49.0 25.2 5e-09 36.5 6.2 3.9 4 0 0 4 4 4 2 EamA-like transporter family TPT PF03151.16 PRP88931.1 - 9.7e-10 38.3 10.3 6.9e-06 25.6 1.1 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family ParA PF10609.9 PRP88932.1 - 1.8e-86 289.6 0.0 2.7e-86 289.0 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DAGK_cat PF00781.24 PRP88932.1 - 6.6e-29 100.1 0.0 3.8e-28 97.6 0.0 2.3 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain GHMP_kinases_N PF00288.26 PRP88932.1 - 5.6e-14 52.1 0.2 1.4e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain CbiA PF01656.23 PRP88932.1 - 4.8e-13 49.3 0.0 1.3e-11 44.6 0.0 2.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GHMP_kinases_C PF08544.13 PRP88932.1 - 2.3e-08 34.3 0.0 6.9e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal AAA_31 PF13614.6 PRP88932.1 - 9.9e-08 32.1 0.0 4.2e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 PRP88932.1 - 4.3e-06 26.2 0.0 9.2e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 PRP88932.1 - 1.4e-05 24.4 2.8 1.8e-05 24.1 0.6 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 PRP88932.1 - 3.1e-05 23.1 0.2 6.3e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 PRP88932.1 - 5e-05 22.9 0.2 0.0027 17.2 0.1 2.6 3 0 0 3 3 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 PRP88932.1 - 0.0016 18.0 0.1 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain GalKase_gal_bdg PF10509.9 PRP88932.1 - 0.0098 15.4 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 1 Galactokinase galactose-binding signature APS_kinase PF01583.20 PRP88932.1 - 0.011 15.6 0.1 0.033 14.1 0.1 1.8 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.6 PRP88932.1 - 0.013 15.3 0.4 6.3 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PRP88932.1 - 0.032 14.6 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain CBP_BcsQ PF06564.12 PRP88932.1 - 0.049 13.1 0.4 0.25 10.8 0.4 2.2 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 PRP88932.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 PRP88932.1 - 0.089 12.0 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain RsgA_GTPase PF03193.16 PRP88932.1 - 0.097 12.6 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 PRP88932.1 - 0.1 12.2 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sin3_corepress PF08295.12 PRP88932.1 - 0.11 12.6 1.0 0.27 11.3 1.0 1.7 1 0 0 1 1 1 0 Sin3 family co-repressor AAA_18 PF13238.6 PRP88932.1 - 0.15 12.6 0.3 1.6 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 PRP88932.1 - 0.16 11.4 0.7 0.39 10.1 0.1 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 PRP88932.1 - 0.3 10.3 1.3 1.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin SH2 PF00017.24 PRP88933.1 - 4.2e-19 68.4 0.0 2.3e-08 34.0 0.0 3.2 3 0 0 3 3 3 2 SH2 domain IBP39 PF11422.8 PRP88933.1 - 0.00058 19.7 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Initiator binding protein 39 kDa Cbl_N2 PF02761.14 PRP88933.1 - 0.00077 20.1 0.0 0.0025 18.5 0.0 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain PP2C_2 PF13672.6 PRP88933.1 - 0.00091 18.9 0.0 0.004 16.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C DUF4869 PF16163.5 PRP88933.1 - 0.01 15.5 0.0 0.045 13.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) Cbl_N3 PF02762.14 PRP88933.1 - 0.03 14.2 0.0 0.55 10.1 0.0 2.6 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain SpoIIE PF07228.12 PRP88933.1 - 0.092 12.7 0.0 0.33 10.8 0.0 1.9 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) YkyA PF10368.9 PRP88933.1 - 7.5 6.2 8.3 1.2 8.8 4.2 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein FYVE_2 PF02318.16 PRP88934.1 - 0.00097 19.3 1.4 0.0016 18.6 1.4 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 PRP88934.1 - 0.023 14.8 2.7 0.041 14.0 2.7 1.4 1 0 0 1 1 1 0 FYVE zinc finger C1_1 PF00130.22 PRP88934.1 - 0.034 14.0 3.4 0.06 13.2 3.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PfkB PF00294.24 PRP88935.1 - 6.2e-63 212.9 0.3 7e-63 212.7 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 PRP88935.1 - 3.4e-05 23.3 0.1 7.4e-05 22.2 0.1 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase RNase_P_Rpp14 PF01900.19 PRP88936.1 - 1.1e-22 80.1 0.1 1.7e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Zip PF02535.22 PRP88937.1 - 9.6e-17 61.2 3.4 9.6e-17 61.2 3.4 3.2 2 1 0 2 2 2 1 ZIP Zinc transporter E1-E2_ATPase PF00122.20 PRP88937.1 - 0.43 10.1 0.0 0.43 10.1 0.0 1.8 3 0 0 3 3 3 0 E1-E2 ATPase FERM_f0 PF16511.5 PRP88938.1 - 1e-07 32.1 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM DUF1980 PF09323.10 PRP88938.1 - 0.054 13.4 1.2 6.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) zf-RING_2 PF13639.6 PRP88939.1 - 2.6e-13 50.1 8.5 4.5e-13 49.3 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP88939.1 - 3.3e-09 36.4 9.1 5.6e-09 35.7 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP88939.1 - 4.2e-09 36.0 3.6 4.2e-09 36.0 3.6 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 PRP88939.1 - 2.7e-07 30.7 10.4 1.1e-06 28.8 10.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PRP88939.1 - 2.8e-07 30.3 8.0 4.7e-07 29.6 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP88939.1 - 7.4e-06 25.7 3.5 1.2e-05 25.0 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP88939.1 - 2.1e-05 24.4 7.1 3e-05 23.9 5.9 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PRP88939.1 - 0.00018 21.3 3.8 0.00018 21.3 3.8 1.8 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP88939.1 - 0.00025 20.9 5.1 0.00025 20.9 5.1 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PRP88939.1 - 0.00053 20.0 4.7 0.0015 18.6 1.9 2.2 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 PRP88939.1 - 0.0024 18.0 1.1 0.0042 17.2 0.6 1.5 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PRP88939.1 - 0.014 15.6 1.3 0.027 14.7 0.7 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 PRP88939.1 - 0.04 13.5 6.1 0.079 12.6 6.1 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 PRP88939.1 - 0.059 13.3 4.3 2.3 8.2 1.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 PRP88939.1 - 0.21 11.5 4.0 0.35 10.7 4.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 PRP88939.1 - 0.22 11.7 4.2 0.53 10.5 4.2 1.7 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 PRP88939.1 - 0.28 11.4 4.5 1.9 8.7 4.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 PRP88939.1 - 1.4 8.9 5.8 3.7 7.5 5.8 1.8 1 1 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 PRP88939.1 - 2.5 8.2 6.9 5.7 7.1 6.9 1.7 1 1 0 1 1 1 0 Zinc-finger Folate_rec PF03024.14 PRP88940.1 - 2.4e-05 24.3 19.3 3.6e-05 23.7 19.3 1.4 1 1 0 1 1 1 1 Folate receptor family F-box_4 PF15966.5 PRP88940.1 - 0.097 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 F-box Phage_antitermQ PF06530.12 PRP88940.1 - 0.68 9.9 2.8 6.4 6.7 0.6 2.2 2 0 0 2 2 2 0 Phage antitermination protein Q GrpE PF01025.19 PRP88941.1 - 1e-40 139.1 0.1 1e-40 139.1 0.1 1.9 2 0 0 2 2 2 1 GrpE ESP PF16590.5 PRP88941.1 - 0.033 14.5 0.1 0.091 13.0 0.1 1.9 1 1 0 1 1 1 0 Exocrine gland-secreting peptide MMR_HSR1 PF01926.23 PRP88942.1 - 2.7e-14 53.2 0.0 5.4e-13 49.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP88942.1 - 1.2e-07 31.4 0.1 4.2e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PRP88942.1 - 4e-05 23.6 0.0 0.055 13.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase zf-rbx1 PF12678.7 PRP88943.1 - 0.013 15.8 4.2 0.06 13.7 4.2 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PRP88943.1 - 0.031 14.6 3.9 0.031 14.6 3.9 3.0 2 1 0 2 2 2 0 Ring finger domain DUF836 PF05768.14 PRP88943.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.0 2 1 0 2 2 2 0 Glutaredoxin-like domain (DUF836) PALP PF00291.25 PRP88944.1 - 1.8e-65 221.3 0.0 2.6e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 PRP88944.1 - 1.1e-12 48.2 0.3 1.7e-07 31.5 0.0 4.0 4 1 0 4 4 4 2 CBS domain DUF1670 PF07900.11 PRP88944.1 - 0.11 11.8 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1670) ATP12 PF07542.11 PRP88945.1 - 1.6e-28 99.3 0.0 2.5e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein RT_RNaseH_2 PF17919.1 PRP88947.1 - 1.2e-24 86.2 0.0 3e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PRP88947.1 - 3.2e-17 62.7 0.0 9.1e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase NusG_II PF07009.11 PRP88947.1 - 0.039 14.2 0.1 0.071 13.3 0.1 1.3 1 0 0 1 1 1 0 NusG domain II DUF5121 PF17165.4 PRP88948.1 - 0.11 12.9 0.3 0.2 12.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5121) Sec61_beta PF03911.16 PRP88951.1 - 8.1e-17 61.0 0.0 1.7e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Sec61beta family 7TMR-HDED PF07697.11 PRP88951.1 - 0.021 14.9 10.1 0.036 14.2 10.1 1.3 1 0 0 1 1 1 0 7TM-HD extracellular UBX PF00789.20 PRP88952.1 - 5.2e-19 68.2 2.3 1.8e-18 66.5 0.1 2.6 3 0 0 3 3 3 1 UBX domain CRAL_TRIO PF00650.20 PRP88953.1 - 6.6e-21 74.7 0.0 1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PRP88953.1 - 1.7e-07 31.5 0.0 2.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TMEM135_C_rich PF15982.5 PRP88953.1 - 0.0078 16.8 0.1 0.097 13.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 UPRTase PF14681.6 PRP88954.1 - 3.5e-80 268.3 0.0 4.1e-80 268.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 PRP88954.1 - 1.8e-05 24.3 0.1 2.8e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain OTU PF02338.19 PRP88955.1 - 2e-11 44.5 0.0 6.6e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease RasGAP PF00616.19 PRP88956.1 - 8.6e-26 90.9 0.0 6.8e-18 65.1 0.1 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 PRP88956.1 - 5.3e-16 59.0 0.5 1.4e-15 57.7 0.3 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 PRP88956.1 - 3.1e-10 40.0 0.0 7.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain Myosin_TH1 PF06017.13 PRP88956.1 - 0.0074 16.0 0.4 0.11 12.2 0.2 2.3 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding Exonuc_VII_L PF02601.15 PRP88957.1 - 0.0023 17.5 2.8 0.0023 17.5 2.8 2.0 2 1 0 2 2 2 1 Exonuclease VII, large subunit DUF4497 PF14924.6 PRP88957.1 - 0.16 12.4 1.4 0.69 10.4 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4497) Herpes_UL6 PF01763.16 PRP88957.1 - 2.7 6.4 5.0 0.76 8.2 1.9 1.5 2 0 0 2 2 2 0 Herpesvirus UL6 like Peptidase_M22 PF00814.25 PRP88958.1 - 9.8e-73 245.2 0.0 5.6e-72 242.7 0.0 1.9 1 1 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 PRP88958.1 - 0.00054 19.7 0.0 0.00086 19.1 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus RNA_Me_trans PF04252.13 PRP88958.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase RelB PF04221.12 PRP88958.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 RelB antitoxin Complex1_LYR PF05347.15 PRP88959.1 - 4.4e-06 26.7 0.2 6.1e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) NUDIX-like PF09296.11 PRP88960.1 - 6.7e-10 39.5 0.1 1.3e-09 38.6 0.1 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 PRP88960.1 - 6.9e-06 25.6 5.6 1.2e-05 24.9 5.6 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX PF00293.28 PRP88960.1 - 0.00011 22.2 0.4 0.0044 17.1 0.1 2.7 2 1 0 2 2 2 1 NUDIX domain VSP PF03302.13 PRP88960.1 - 0.038 12.8 0.2 0.05 12.4 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SapB_1 PF05184.15 PRP88961.1 - 2.4e-11 43.4 6.6 0.00016 21.6 0.3 4.5 4 0 0 4 4 4 3 Saposin-like type B, region 1 SapB_2 PF03489.17 PRP88961.1 - 4.8e-07 29.8 3.5 0.0004 20.4 0.1 4.3 4 0 0 4 4 4 2 Saposin-like type B, region 2 Pectate_lyase_3 PF12708.7 PRP88963.1 - 2.1e-59 201.0 13.2 9.5e-53 179.2 2.8 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein WD40 PF00400.32 PRP88964.1 - 8.5e-39 130.9 19.9 7.1e-07 29.8 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP88964.1 - 3.7e-15 56.0 1.3 0.00018 21.7 0.2 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP88964.1 - 6.2e-07 29.5 0.9 0.073 12.9 0.0 3.2 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 PRP88964.1 - 4.7e-06 26.4 2.4 0.017 14.8 0.3 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Cytochrom_D1 PF02239.16 PRP88964.1 - 0.041 12.4 0.2 1.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 PRP88964.1 - 0.053 12.5 0.8 9.7 5.0 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 PRP88964.1 - 0.069 12.7 0.8 7.3 6.1 0.0 3.0 1 1 0 2 2 2 0 PQQ-like domain UcrQ PF02939.16 PRP88966.1 - 5.3e-08 32.7 0.0 6.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 PRP88966.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Ank_4 PF13637.6 PRP88967.1 - 2.7e-05 24.6 0.1 6.9 7.4 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeats (many copies) F-box-like PF12937.7 PRP88967.1 - 0.00023 21.0 0.5 0.00053 19.8 0.5 1.6 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 PRP88967.1 - 0.0019 18.7 0.0 0.12 13.0 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP88967.1 - 0.005 17.1 0.0 0.28 11.6 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP88967.1 - 0.027 15.0 0.1 26 5.8 0.0 4.5 5 0 0 5 5 5 0 Ankyrin repeat F-box PF00646.33 PRP88967.1 - 0.11 12.4 0.4 0.31 11.0 0.4 1.8 1 0 0 1 1 1 0 F-box domain ATX_III PF08098.11 PRP88967.1 - 0.17 11.9 0.4 0.17 11.9 0.4 2.9 3 0 0 3 3 3 0 Anemonia sulcata toxin III family FKBP_C PF00254.28 PRP88968.1 - 4.7e-34 116.6 0.0 6.1e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pkinase_Tyr PF07714.17 PRP88969.1 - 1.4e-51 175.3 0.0 2.4e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88969.1 - 1.6e-45 155.6 0.0 2.5e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Amino_oxidase PF01593.24 PRP88969.1 - 2.2e-32 113.0 0.0 3e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP88969.1 - 1.6e-13 50.6 0.0 4.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SH2 PF00017.24 PRP88969.1 - 4.9e-09 36.2 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Pyr_redox_2 PF07992.14 PRP88969.1 - 1.1e-07 31.4 0.0 0.00022 20.6 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP88969.1 - 2.8e-07 30.0 0.8 4.1e-05 22.9 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 PRP88969.1 - 1.1e-06 28.4 0.4 0.017 14.7 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase GDI PF00996.18 PRP88969.1 - 1.9e-05 23.4 0.2 0.02 13.4 0.0 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor HI0933_like PF03486.14 PRP88969.1 - 2.3e-05 23.3 0.2 0.0067 15.2 1.2 2.2 2 0 0 2 2 2 1 HI0933-like protein Haspin_kinase PF12330.8 PRP88969.1 - 0.00067 18.7 0.2 0.018 14.0 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain Thi4 PF01946.17 PRP88969.1 - 0.0017 17.6 0.1 0.0048 16.2 0.1 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 PRP88969.1 - 0.004 17.7 2.2 0.085 13.4 0.7 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PRP88969.1 - 0.0083 15.3 6.9 0.011 14.9 0.5 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PRP88969.1 - 0.019 14.2 0.1 0.059 12.6 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 PRP88969.1 - 0.041 12.9 0.1 0.13 11.2 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 PRP88969.1 - 0.043 13.7 0.3 0.14 12.0 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 PRP88969.1 - 0.061 12.7 1.7 0.15 11.4 1.2 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PRP88969.1 - 0.074 12.3 0.3 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase APH PF01636.23 PRP88969.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family AlaDh_PNT_C PF01262.21 PRP88969.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Kdo PF06293.14 PRP88969.1 - 0.14 11.5 0.0 0.4 10.0 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EGF_2 PF07974.13 PRP88970.1 - 0.003 17.9 7.0 0.0057 17.0 7.0 1.5 1 0 0 1 1 1 1 EGF-like domain Pkinase_Tyr PF07714.17 PRP88971.1 - 1.3e-18 67.3 0.2 2.1e-18 66.6 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88971.1 - 5.3e-13 48.9 0.1 9.3e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP88971.1 - 5.7e-12 45.2 14.1 1.3e-05 24.9 3.9 4.1 2 1 2 4 4 4 3 Leucine rich repeat GPS PF01825.21 PRP88971.1 - 1e-07 32.4 3.2 2.6e-07 31.1 3.2 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP88971.1 - 1.7e-05 25.0 20.9 0.068 13.6 1.3 5.1 1 1 4 6 6 6 4 Leucine Rich repeats (2 copies) EF-G-binding_N PF07299.11 PRP88971.1 - 0.2 12.2 1.5 29 5.3 0.0 3.0 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal RasGEF PF00617.19 PRP88972.1 - 3.4e-34 118.6 0.0 9.7e-34 117.1 0.0 1.8 1 0 0 1 1 1 1 RasGEF domain V4R PF02830.18 PRP88972.1 - 1.6e-14 53.6 2.3 2.7e-06 27.3 0.7 2.7 2 0 0 2 2 2 2 V4R domain 2OG-FeII_Oxy_2 PF13532.6 PRP88972.1 - 1.3e-07 32.0 0.0 1e-06 29.1 0.0 2.5 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Rft-1 PF04506.13 PRP88973.1 - 6.9e-62 209.8 19.4 1e-61 209.3 19.4 1.2 1 0 0 1 1 1 1 Rft protein 7TMR-DISM_7TM PF07695.11 PRP88973.1 - 0.0038 17.1 9.3 0.0038 17.1 9.3 3.1 3 1 0 3 3 3 1 7TM diverse intracellular signalling DUF2208 PF09973.9 PRP88973.1 - 0.053 13.1 0.9 0.14 11.7 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF2516 PF10724.9 PRP88973.1 - 0.98 9.7 0.0 0.98 9.7 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) Abhydrolase_3 PF07859.13 PRP88974.1 - 2.3e-48 164.9 0.0 9.3e-48 162.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold HSL_N PF06350.12 PRP88974.1 - 3.1e-14 52.6 0.0 5.2e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Hormone-sensitive lipase (HSL) N-terminus Say1_Mug180 PF10340.9 PRP88974.1 - 2.2e-06 26.8 0.0 3.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 PRP88974.1 - 0.00026 20.0 0.4 0.0015 17.5 0.4 2.0 1 1 0 1 1 1 1 Carboxylesterase family CDC45 PF02724.14 PRP88974.1 - 0.0072 14.7 0.6 0.0072 14.7 0.6 2.1 2 0 0 2 2 2 1 CDC45-like protein DLH PF01738.18 PRP88974.1 - 0.048 13.2 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family TCR PF03638.15 PRP88975.1 - 7.8e-24 83.7 50.3 5.8e-12 45.7 23.1 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain BTB_2 PF02214.22 PRP88975.1 - 1.4e-20 73.5 0.1 6.3e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain TLD PF07534.16 PRP88975.1 - 4.4e-12 46.4 0.1 8.9e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 TLD MSL2-CXC PF16682.5 PRP88975.1 - 0.074 13.2 41.7 1.2 9.4 16.3 2.5 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 SPICE PF15678.5 PRP88976.1 - 3.9e-07 29.8 0.7 3.9e-07 29.8 0.7 4.0 2 1 2 4 4 4 1 Centriole duplication and mitotic chromosome congression HSP70 PF00012.20 PRP88976.1 - 0.44 8.7 11.0 0.9 7.6 11.0 1.5 1 0 0 1 1 1 0 Hsp70 protein GP41 PF00517.17 PRP88976.1 - 1.1 9.1 7.8 5 7.0 7.6 2.2 1 1 0 1 1 1 0 Retroviral envelope protein Tam41_Mmp37 PF09139.11 PRP88976.1 - 1.5 8.2 9.9 0.19 11.1 5.4 1.8 2 0 0 2 2 2 0 Phosphatidate cytidylyltransferase, mitochondrial Prominin PF05478.11 PRP88976.1 - 1.7 6.5 9.7 3.7 5.4 9.7 1.5 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 PRP88976.1 - 4.9 4.9 14.5 10 3.9 14.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FHIPEP PF00771.20 PRP88976.1 - 7.3 4.9 10.1 12 4.2 10.1 1.3 1 0 0 1 1 1 0 FHIPEP family COG2 PF06148.11 PRP88976.1 - 8.1 6.5 20.9 0.23 11.5 0.9 4.1 3 1 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 LRR_6 PF13516.6 PRP88977.1 - 7.7e-24 81.7 24.5 0.00062 19.6 0.1 8.5 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 PRP88977.1 - 2.4e-05 24.6 19.3 0.22 12.0 0.6 6.0 3 2 1 4 4 4 4 Leucine Rich repeats (2 copies) PriCT_1 PF08708.11 PRP88977.1 - 0.021 14.6 0.1 0.33 10.7 0.0 2.8 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) LRR_8 PF13855.6 PRP88977.1 - 0.026 14.3 17.7 0.79 9.5 0.1 6.5 3 2 2 5 5 5 0 Leucine rich repeat DUF262 PF03235.14 PRP88977.1 - 0.14 12.3 3.0 0.16 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF262 Mob1_phocein PF03637.17 PRP88978.1 - 1.3e-60 204.3 0.7 1.5e-60 204.1 0.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family PKD PF00801.20 PRP88978.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 PKD domain ParA PF10609.9 PRP88979.1 - 7.5e-99 330.2 0.0 8.5e-99 330.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 PRP88979.1 - 1.7e-13 50.7 0.0 1.4e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PRP88979.1 - 2.6e-08 34.0 1.7 8e-07 29.1 1.7 2.2 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 PRP88979.1 - 3.8e-08 33.0 0.0 1.1e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 PRP88979.1 - 6.3e-08 32.2 4.1 4.5e-07 29.4 1.1 2.7 2 1 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 PRP88979.1 - 0.00027 20.5 0.0 0.00066 19.2 0.1 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 PRP88979.1 - 0.00044 19.9 0.2 0.00069 19.2 0.2 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 PRP88979.1 - 0.00088 18.3 0.3 0.0013 17.8 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 PRP88979.1 - 0.0036 17.2 0.6 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 PRP88979.1 - 0.0045 16.6 0.2 0.063 12.9 0.2 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain APS_kinase PF01583.20 PRP88979.1 - 0.0058 16.5 0.1 0.0083 16.0 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase CBP_BcsQ PF06564.12 PRP88979.1 - 0.027 13.9 0.5 0.056 12.9 0.5 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ IstB_IS21 PF01695.17 PRP88979.1 - 0.033 13.9 0.2 0.064 13.0 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CLP1_P PF16575.5 PRP88979.1 - 0.039 13.7 0.1 0.07 12.9 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop VirC1 PF07015.11 PRP88979.1 - 0.046 13.0 0.1 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 VirC1 protein RsgA_GTPase PF03193.16 PRP88979.1 - 0.072 13.0 0.9 0.13 12.1 0.9 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 PRP88979.1 - 0.16 11.8 0.5 0.34 10.8 0.3 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 PRP88979.1 - 0.19 10.9 0.3 0.31 10.2 0.3 1.3 1 0 0 1 1 1 0 NB-ARC domain DSPc PF00782.20 PRP88980.1 - 1.7e-15 57.0 0.0 2.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 PRP88980.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) AMPK1_CBM PF16561.5 PRP88981.1 - 2.6e-23 82.0 1.7 3.1e-12 46.5 0.2 2.3 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase Pur_ac_phosph_N PF16656.5 PRP88981.1 - 2.6e-06 27.9 3.6 0.019 15.5 0.1 3.1 2 1 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain CBM_48 PF02922.18 PRP88981.1 - 4.1e-05 23.9 1.3 0.035 14.4 0.1 2.4 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) fn3 PF00041.21 PRP88981.1 - 0.0024 18.2 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain CCT PF06203.14 PRP88981.1 - 0.79 9.8 3.5 10 6.2 0.2 3.1 3 0 0 3 3 3 0 CCT motif FUSC PF04632.12 PRP88981.1 - 3.3 6.1 13.0 7.2 5.0 13.0 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family adh_short PF00106.25 PRP88984.1 - 2.7e-18 66.1 0.0 4.2e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PRP88984.1 - 7.7e-09 35.4 0.0 1.3e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP88984.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 PRP88984.1 - 0.0068 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 PRP88984.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 PRP88984.1 - 0.027 14.7 0.0 0.098 12.9 0.0 1.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 PRP88984.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family EBP PF05241.12 PRP88985.1 - 1.3e-16 60.5 3.9 2.3e-16 59.8 3.9 1.3 1 0 0 1 1 1 1 Emopamil binding protein LIM PF00412.22 PRP88985.1 - 7.8e-11 42.0 6.6 1.6e-10 41.1 6.6 1.5 1 0 0 1 1 1 1 LIM domain DUF4833 PF16117.5 PRP88985.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4833) Ost5 PF05251.12 PRP88985.1 - 2.2 8.6 9.6 1.3 9.3 5.0 2.6 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 UCH PF00443.29 PRP88987.1 - 6.9e-50 169.9 2.6 4.5e-49 167.3 2.6 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP88987.1 - 9.8e-10 38.5 12.0 1.5e-07 31.3 12.0 3.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 PRP88987.1 - 1.8e-06 27.4 1.7 0.00048 19.8 0.3 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-C4pol PF14260.6 PRP88987.1 - 0.061 13.8 0.6 0.19 12.2 0.6 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF3774 PF12609.8 PRP88987.1 - 6.6 7.8 8.3 0.54 11.3 0.9 3.0 3 0 0 3 3 3 0 Wound-induced protein Beach PF02138.18 PRP88988.1 - 9.5e-119 395.8 0.0 1.4e-118 395.2 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 PRP88988.1 - 4.7e-29 101.5 1.1 8.2e-29 100.7 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) PH PF00169.29 PRP88988.1 - 6e-20 71.7 2.5 1.1e-19 70.9 0.2 2.7 3 0 0 3 3 3 1 PH domain PH_BEACH PF14844.6 PRP88988.1 - 5.9e-15 55.2 0.0 1.7e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 PRP88988.1 - 2.9e-10 40.6 0.1 1.1e-05 26.1 0.1 4.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP88988.1 - 1.4e-05 25.3 0.4 0.69 10.3 0.0 3.6 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Laminin_G_3 PF13385.6 PRP88988.1 - 2.1e-05 24.7 0.1 5.3e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_11 PF15413.6 PRP88988.1 - 4.3e-05 23.9 1.6 0.00089 19.6 1.6 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain DUF4800 PF16057.5 PRP88988.1 - 0.019 14.3 0.3 0.048 12.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) Cytochrom_D1 PF02239.16 PRP88988.1 - 0.11 11.0 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Pentaxin PF00354.17 PRP88988.1 - 0.15 11.7 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 Pentaxin family COX6B PF02297.17 PRP88989.1 - 3.6e-14 52.7 1.4 5.4e-14 52.2 1.4 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb ketoacyl-synt PF00109.26 PRP88989.1 - 0.082 12.5 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain WW PF00397.26 PRP88989.1 - 2.6 8.2 5.0 0.39 10.8 1.1 1.6 2 0 0 2 2 2 0 WW domain TraB PF01963.17 PRP88990.1 - 2.3e-26 93.2 0.0 3.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 TraB family CBM_20 PF00686.19 PRP88991.1 - 6.1e-13 48.5 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain RabGAP-TBC PF00566.18 PRP88991.1 - 0.00027 20.7 0.3 0.081 12.6 0.0 3.5 2 1 1 3 3 3 1 Rab-GTPase-TBC domain Pkinase PF00069.25 PRP88992.1 - 1.4e-53 182.0 0.1 2.9e-53 180.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP88992.1 - 4.3e-38 131.1 0.0 6.9e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP88992.1 - 1.8e-05 24.2 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PRP88992.1 - 0.084 12.8 0.1 0.67 9.8 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP88992.1 - 0.09 11.5 0.0 0.09 11.5 0.0 1.9 2 1 0 2 2 2 0 Fungal protein kinase Lipase_3 PF01764.25 PRP88993.1 - 2.7e-36 124.6 0.0 3.6e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 PRP88993.1 - 0.00011 21.9 0.0 0.002 17.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 PRP88993.1 - 0.0045 16.7 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 PRP88993.1 - 0.0071 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP88993.1 - 0.025 15.2 0.0 0.031 14.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_24 PF13479.6 PRP88993.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.17 PRP88994.1 - 4.8e-56 189.9 0.0 1.3e-55 188.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP88994.1 - 5.8e-36 124.2 0.0 1.1e-35 123.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 PRP88994.1 - 1.3e-11 44.4 5.9 1.3e-11 44.4 5.9 7.9 7 1 1 8 8 8 2 IPT/TIG domain WD40 PF00400.32 PRP88994.1 - 0.00061 20.6 16.1 0.12 13.3 0.9 6.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Kdo PF06293.14 PRP88994.1 - 0.0099 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC4_WD40 PF12894.7 PRP88994.1 - 0.024 14.9 0.4 4.7 7.6 0.0 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PEGA PF08308.11 PRP88994.1 - 0.031 14.2 0.0 0.25 11.3 0.0 2.6 1 0 0 1 1 1 0 PEGA domain Syndecan PF01034.20 PRP88994.1 - 0.05 13.5 3.0 0.12 12.3 3.0 1.5 1 0 0 1 1 1 0 Syndecan domain zf-UBP PF02148.19 PRP88994.1 - 0.11 12.9 0.7 0.41 11.0 0.7 1.9 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Pkinase_Tyr PF07714.17 PRP88996.1 - 1.2e-51 175.6 0.0 6.2e-50 169.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase UAA PF08449.11 PRP88996.1 - 2.4e-48 164.9 22.8 6.3e-48 163.5 22.8 1.8 1 0 0 1 1 1 1 UAA transporter family Pkinase PF00069.25 PRP88996.1 - 1.1e-32 113.4 0.0 1.9e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP88996.1 - 4.6e-09 36.7 6.1 4.6e-09 36.7 6.1 2.2 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif Kelch_5 PF13854.6 PRP88996.1 - 0.008 16.2 0.8 1.3 9.1 0.0 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 PRP88996.1 - 0.075 13.0 2.7 9.6 6.3 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_2 PF07646.15 PRP88996.1 - 0.63 10.1 4.6 11 6.2 0.0 3.8 3 0 0 3 3 3 0 Kelch motif DUF1295 PF06966.12 PRP88997.1 - 6.7e-38 130.5 15.5 1.8e-36 125.9 15.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 PRP88997.1 - 0.03 14.7 1.5 0.074 13.5 0.0 2.5 2 2 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-UBR PF02207.20 PRP88998.1 - 1.3e-18 66.9 11.3 1.3e-18 66.9 11.3 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ELL PF10390.9 PRP88998.1 - 0.018 14.5 0.4 0.018 14.5 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL zf-RING_UBOX PF13445.6 PRP88998.1 - 0.045 13.8 0.1 0.17 11.9 0.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PRP88998.1 - 0.12 12.3 3.9 0.57 10.1 0.2 3.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ring_hydroxyl_A PF00848.19 PRP89000.1 - 1.2e-27 97.3 0.0 4.7e-25 88.8 0.0 2.4 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 PRP89000.1 - 2e-13 50.1 0.0 3.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain LCAT PF02450.15 PRP89001.1 - 1.7e-37 129.5 0.4 4.2e-34 118.4 0.1 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 PRP89001.1 - 0.0039 16.7 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.11 PRP89001.1 - 0.0064 15.8 0.1 0.37 10.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 PRP89001.1 - 0.039 13.7 0.0 0.093 12.4 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 PRP89001.1 - 0.061 13.9 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.25 PRP89002.1 - 8.3e-30 103.7 0.1 1.1e-29 103.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP89002.1 - 1e-24 87.4 0.0 1.4e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP89002.1 - 3e-09 37.0 0.1 4.2e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 KR domain H2TH PF06831.14 PRP89002.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain TPR_2 PF07719.17 PRP89003.1 - 0.054 13.6 0.0 0.6 10.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat IPP-2 PF04979.14 PRP89004.1 - 0.72 10.6 6.7 0.26 12.0 3.4 2.1 2 1 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) DUF1388 PF07142.12 PRP89004.1 - 9.8 6.2 12.3 0.4 10.7 0.2 4.0 4 1 0 4 4 4 0 Repeat of unknown function (DUF1388) HIT PF01230.23 PRP89005.1 - 1.1e-30 106.2 0.7 1.4e-30 105.9 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 PRP89005.1 - 1.6e-22 80.1 0.9 1.9e-22 79.9 0.1 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Metallophos PF00149.28 PRP89006.1 - 6.3e-14 52.9 0.1 1.6e-13 51.7 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1084 PF06454.11 PRP89006.1 - 0.0016 17.9 12.9 0.0024 17.3 12.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) SapB_1 PF05184.15 PRP89006.1 - 0.012 15.6 1.3 0.042 13.9 1.3 2.1 1 0 0 1 1 1 0 Saposin-like type B, region 1 Exo_endo_phos_2 PF14529.6 PRP89006.1 - 0.098 12.5 0.3 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase DUF2981 PF11200.8 PRP89009.1 - 0.0015 18.3 5.3 0.0025 17.6 5.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2981) Aldedh PF00171.22 PRP89012.1 - 4.6e-99 332.0 0.0 6.2e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AbiEi_1 PF09407.10 PRP89012.1 - 0.022 15.1 0.1 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 AbiEi antitoxin C-terminal domain PARM PF17061.5 PRP89012.1 - 3.4 7.7 28.1 1.3 9.1 8.6 2.2 2 0 0 2 2 2 0 PARM ENOD93 PF03386.14 PRP89013.1 - 1.9e-08 34.0 0.3 2.4e-08 33.8 0.3 1.1 1 0 0 1 1 1 1 Early nodulin 93 ENOD93 protein PseudoU_synth_2 PF00849.22 PRP89014.1 - 1.5e-25 90.1 0.1 2.6e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase MFS_1 PF07690.16 PRP89014.1 - 7.2e-20 71.2 29.4 7.2e-20 71.2 29.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 PRP89014.1 - 1.1e-16 60.4 21.1 1.6e-16 59.8 21.1 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector Homeodomain PF00046.29 PRP89014.1 - 4.1e-16 58.6 4.2 8.3e-16 57.6 4.2 1.5 1 0 0 1 1 1 1 Homeodomain S4 PF01479.25 PRP89014.1 - 5.8e-10 38.7 0.1 1.4e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 S4 domain Homeobox_KN PF05920.11 PRP89014.1 - 3.6e-08 33.2 0.1 9e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain SRF-TF PF00319.18 PRP89015.1 - 6.1e-21 73.6 0.3 1.2e-20 72.7 0.3 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ras PF00071.22 PRP89016.1 - 5.4e-42 143.1 0.0 1e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89016.1 - 6.8e-10 39.2 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89016.1 - 1.4e-05 24.7 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Glyco_hydro_38N PF01074.22 PRP89017.1 - 2e-78 263.7 7.1 3e-78 263.1 7.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP89017.1 - 5e-22 79.0 0.8 2.1e-17 64.0 0.0 2.8 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PRP89017.1 - 5.7e-12 45.6 0.5 1.6e-11 44.2 0.5 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PRP89017.1 - 1.9e-08 34.3 0.0 4.8e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Enolase_C PF00113.22 PRP89020.1 - 4e-154 512.1 0.2 5.1e-154 511.8 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PRP89020.1 - 9.5e-59 197.3 0.0 1.4e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 PRP89020.1 - 2.6e-07 30.4 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 PRP89020.1 - 0.00038 19.7 0.1 0.00062 19.0 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Pyr_redox_2 PF07992.14 PRP89021.1 - 2.6e-13 49.9 0.0 2.9e-05 23.5 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase LBP_BPI_CETP PF01273.25 PRP89021.1 - 2.8e-12 46.5 0.0 5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain BAR_3 PF16746.5 PRP89021.1 - 1.9e-09 37.6 5.0 3.7e-09 36.7 5.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 PRP89021.1 - 5.2e-08 32.8 4.6 1e-07 31.9 4.6 1.5 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 PRP89021.1 - 0.0038 16.4 5.2 0.0092 15.1 5.2 1.7 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Pyr_redox PF00070.27 PRP89021.1 - 0.0043 17.6 0.6 4.7 7.8 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PRP89021.1 - 0.0099 15.2 0.0 4.4 6.5 0.0 2.7 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 PRP89021.1 - 0.054 13.1 0.1 0.46 10.0 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PRP89021.1 - 0.07 13.4 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PRP89021.1 - 0.081 12.9 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding SMC_N PF02463.19 PRP89023.1 - 1.3e-70 237.3 21.6 1.3e-70 237.3 21.6 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PRP89023.1 - 1.9e-20 73.3 0.0 6.5e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PRP89023.1 - 1e-11 45.3 10.4 2.2e-06 27.7 0.3 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PRP89023.1 - 1.3e-08 34.9 17.6 1.3e-08 34.9 17.6 5.2 3 2 0 3 3 1 1 AAA ATPase domain AAA_23 PF13476.6 PRP89023.1 - 4.1e-08 34.0 17.8 4.1e-08 34.0 17.8 8.0 3 2 2 5 5 1 1 AAA domain AAA_29 PF13555.6 PRP89023.1 - 1.6e-05 24.5 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.9 PRP89023.1 - 0.0034 17.4 5.0 0.0034 17.4 5.0 9.4 3 3 6 9 9 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.6 PRP89023.1 - 0.065 13.5 0.3 78 3.5 0.0 4.5 4 0 0 4 4 4 0 AAA domain SbcCD_C PF13558.6 PRP89023.1 - 0.086 13.1 0.1 1.1 9.5 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UpxZ PF06603.11 PRP89023.1 - 0.13 12.6 1.6 0.66 10.3 1.6 2.3 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists ABC_tran PF00005.27 PRP89023.1 - 1.5 9.3 0.0 1.3 9.6 0.2 6.7 5 2 1 6 6 5 0 ABC transporter SKA1 PF07160.12 PRP89024.1 - 7.8e-47 160.1 0.6 1.3e-46 159.4 0.6 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 TFIIE_alpha PF02002.17 PRP89024.1 - 0.024 14.5 0.1 0.055 13.3 0.1 1.6 1 0 0 1 1 1 0 TFIIE alpha subunit TRAF_BIRC3_bd PF16673.5 PRP89024.1 - 0.026 14.3 0.8 0.026 14.3 0.8 2.6 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain MSP1b PF03429.13 PRP89024.1 - 0.041 12.0 0.4 0.052 11.6 0.4 1.1 1 0 0 1 1 1 0 Major surface protein 1B SCO1-SenC PF02630.14 PRP89024.1 - 0.046 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC DUF16 PF01519.16 PRP89024.1 - 6.4 7.3 6.7 1.1 9.7 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function DUF16 SH3_1 PF00018.28 PRP89025.1 - 1.9e-13 49.8 0.1 3.5e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 PRP89025.1 - 1.1e-11 44.4 0.1 2.3e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 PRP89025.1 - 8.7e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain PPO1_KFDV PF12143.8 PRP89025.1 - 3.9 7.6 7.9 17 5.5 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF_B2219) LysM PF01476.20 PRP89026.1 - 0.12 12.4 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 LysM domain OMPdecase PF00215.24 PRP89027.1 - 5.6e-62 209.3 0.0 8.5e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 PRP89027.1 - 1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Sec7 PF01369.20 PRP89029.1 - 2.2e-32 112.2 0.1 8.9e-32 110.2 0.1 1.8 1 1 0 1 1 1 1 Sec7 domain F-box-like PF12937.7 PRP89029.1 - 2.4e-07 30.5 0.9 5.8e-07 29.3 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP89029.1 - 1.8e-05 24.4 0.3 3.9e-05 23.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP89029.1 - 0.003 17.4 0.1 0.0057 16.5 0.1 1.5 1 0 0 1 1 1 1 F-box Elongin_A PF06881.11 PRP89029.1 - 0.0072 16.8 0.2 0.016 15.7 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Ank_2 PF12796.7 PRP89030.1 - 0.0059 17.2 0.0 4.5 7.9 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP89030.1 - 0.088 13.4 0.5 5.3 7.9 0.0 4.2 5 0 0 5 5 5 0 Ankyrin repeat F-box PF00646.33 PRP89030.1 - 0.091 12.7 0.1 0.091 12.7 0.1 2.9 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 PRP89030.1 - 0.77 9.7 10.1 0.21 11.5 1.3 3.3 3 1 1 4 4 4 0 F-box-like Peroxin-3 PF04882.12 PRP89031.1 - 2.7e-38 132.2 4.0 1.4e-31 110.0 0.4 2.8 1 1 1 2 2 2 2 Peroxin-3 Ferritin PF00210.24 PRP89031.1 - 0.019 14.9 0.1 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 Ferritin-like domain RBP_receptor PF14752.6 PRP89031.1 - 0.09 11.3 0.4 0.12 10.9 0.4 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor Vault_4 PF17796.1 PRP89031.1 - 0.16 12.1 0.2 0.45 10.6 0.2 1.7 1 0 0 1 1 1 0 Major Vault Protein repeat domain SKA2 PF16740.5 PRP89032.1 - 3.3e-17 62.3 2.2 4e-17 62.0 2.2 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Sec34 PF04136.15 PRP89032.1 - 0.0055 16.6 1.1 0.0097 15.8 0.6 1.7 1 1 1 2 2 2 1 Sec34-like family RWP-RK PF02042.15 PRP89033.1 - 9.8e-07 28.7 0.2 1.7e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 PRP89033.1 - 0.00015 21.5 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family HTH_23 PF13384.6 PRP89033.1 - 0.00049 19.8 0.0 0.004 16.9 0.0 2.5 1 1 1 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 PRP89033.1 - 0.00099 19.1 0.0 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix HTH_psq PF05225.16 PRP89033.1 - 0.0018 18.0 0.5 0.0041 16.8 0.0 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_24 PF13412.6 PRP89033.1 - 0.028 14.0 0.2 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_28 PF13518.6 PRP89033.1 - 0.054 13.6 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 PRP89033.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Sigma70_r4_2 PF08281.12 PRP89033.1 - 0.13 11.9 0.1 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 adh_short PF00106.25 PRP89035.1 - 6.6e-38 130.1 0.0 2.7e-15 56.3 0.0 4.1 4 0 0 4 4 4 4 short chain dehydrogenase adh_short_C2 PF13561.6 PRP89035.1 - 3.5e-17 62.7 0.0 3.6e-05 23.5 0.0 4.1 3 1 1 4 4 4 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PRP89035.1 - 7.2e-17 61.9 0.1 1.2e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 PRP89035.1 - 1.3e-05 24.7 0.0 0.085 12.3 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 PRP89035.1 - 5.6e-05 23.2 0.0 0.42 10.7 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 PRP89035.1 - 6e-05 23.3 0.1 0.94 9.7 0.0 3.3 4 1 0 4 4 4 2 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 PRP89035.1 - 0.0001 21.5 0.1 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Melibiase_2_C PF17450.2 PRP89035.1 - 0.00063 19.9 0.1 3.1 8.1 0.0 3.1 2 1 0 2 2 2 2 Alpha galactosidase A C-terminal beta sandwich domain Toprim_4 PF13662.6 PRP89035.1 - 0.0092 16.4 0.4 6.8 7.2 0.1 3.6 2 2 1 3 3 3 1 Toprim domain DUF2591 PF10765.9 PRP89035.1 - 0.025 14.9 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2591) DUF4417 PF14386.6 PRP89035.1 - 0.035 13.7 0.0 10 5.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4417) PRP8_domainIV PF12134.8 PRP89035.1 - 0.12 12.0 0.1 17 5.0 0.0 2.3 2 0 0 2 2 2 0 PRP8 domain IV core Pkinase_Tyr PF07714.17 PRP89036.1 - 7.4e-74 248.3 0.0 1.1e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89036.1 - 2.4e-51 174.6 0.0 3.6e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 PRP89036.1 - 2.7e-10 40.2 5.7 2.7e-10 40.2 5.7 7.2 8 2 1 9 9 9 2 IPT/TIG domain Kdo PF06293.14 PRP89036.1 - 0.00025 20.5 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glycophorin_A PF01102.18 PRP89036.1 - 0.011 16.0 0.1 0.035 14.4 0.1 1.9 1 0 0 1 1 1 0 Glycophorin A Pkinase_fungal PF17667.1 PRP89036.1 - 0.027 13.3 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 PRP89036.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Syndecan PF01034.20 PRP89036.1 - 1.1 9.2 5.1 0.58 10.1 2.7 1.8 2 0 0 2 2 2 0 Syndecan domain Pkinase_Tyr PF07714.17 PRP89037.1 - 1.5e-62 211.2 0.3 4.7e-62 209.6 0.3 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89037.1 - 2.3e-44 151.8 0.0 4.7e-44 150.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain TIG PF01833.24 PRP89037.1 - 8.9e-10 38.5 5.6 8.9e-10 38.5 5.6 5.7 4 1 0 4 4 4 1 IPT/TIG domain Kdo PF06293.14 PRP89037.1 - 0.00047 19.6 0.0 0.0009 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E1B_55K PF01696.17 PRP89037.1 - 0.0051 15.5 0.8 0.0051 15.5 0.8 2.1 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen GTP_EFTU PF00009.27 PRP89038.1 - 7.5e-29 100.7 0.0 1.7e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP89038.1 - 2.7e-06 27.5 0.1 6.2e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 PRP89038.1 - 1.5e-05 25.3 0.3 4.6e-05 23.7 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 PRP89038.1 - 0.00022 20.7 0.0 0.00081 18.9 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 PRP89038.1 - 0.001 18.7 1.5 0.0075 15.9 0.0 2.5 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain RIBIOP_C PF04950.12 PRP89038.1 - 0.0012 18.4 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Gtr1_RagA PF04670.12 PRP89038.1 - 0.0046 16.3 0.1 0.017 14.4 0.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 PRP89038.1 - 0.024 14.4 0.1 7.1 6.3 0.0 3.5 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Arf PF00025.21 PRP89038.1 - 0.082 12.4 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF1624 PF07786.12 PRP89041.1 - 7.5e-07 28.9 3.9 7.5e-07 28.9 3.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1624) DUF5009 PF16401.5 PRP89041.1 - 8.2e-05 22.2 2.7 0.0029 17.1 2.7 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5009) MCD PF05292.11 PRP89042.1 - 5.7e-53 180.1 0.0 8.4e-52 176.3 0.0 2.1 1 1 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain Asp PF00026.23 PRP89043.1 - 7e-36 124.2 8.1 7.4e-34 117.6 8.1 2.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PRP89043.1 - 9.2e-20 71.6 3.7 1.7e-19 70.7 3.7 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 PRP89043.1 - 9.8e-16 57.9 0.1 4.2e-15 55.9 0.1 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Pkinase PF00069.25 PRP89044.1 - 1.9e-65 220.9 0.0 2.3e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89044.1 - 6.7e-49 166.5 0.0 8.7e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP89044.1 - 3.2e-07 29.5 0.0 4.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP89044.1 - 9.9e-06 25.1 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP89044.1 - 0.051 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3245 PF11595.8 PRP89044.1 - 0.15 12.6 3.3 0.29 11.6 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) RXT2_N PF08595.11 PRP89044.1 - 0.17 11.9 1.4 0.28 11.2 1.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal APH PF01636.23 PRP89044.1 - 0.18 11.7 0.0 1.1 9.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FAM176 PF14851.6 PRP89044.1 - 0.21 11.3 1.5 0.35 10.5 1.5 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 PRP89044.1 - 0.31 11.4 8.4 0.66 10.4 8.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 PRP89044.1 - 0.68 9.6 7.9 1.2 8.8 7.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 PRP89044.1 - 2.5 7.3 6.9 4.1 6.6 6.9 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 PRP89044.1 - 2.8 7.0 9.5 4.1 6.4 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pam17 PF08566.10 PRP89045.1 - 0.041 13.7 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 PEP-CTERM PF07589.11 PRP89045.1 - 0.13 12.4 1.5 0.25 11.5 1.5 1.5 1 0 0 1 1 1 0 PEP-CTERM motif VPDSG-CTERM PF18205.1 PRP89045.1 - 1.4 8.8 3.5 2.6 7.9 3.5 1.5 1 0 0 1 1 1 0 VPDSG-CTERM motif HA PF03457.14 PRP89046.1 - 7.4e-05 23.0 2.9 0.00061 20.1 0.1 2.9 2 0 0 2 2 2 1 Helicase associated domain OEP PF02321.18 PRP89046.1 - 0.059 13.2 1.0 0.14 12.0 1.0 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein SlyX PF04102.12 PRP89046.1 - 0.41 11.3 3.6 1.9 9.2 0.9 3.5 2 1 0 2 2 2 0 SlyX UDPGP PF01704.18 PRP89047.1 - 1.1e-126 422.8 0.0 1.3e-126 422.6 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase SQS_PSY PF00494.19 PRP89049.1 - 5.3e-64 216.2 0.1 6.8e-64 215.9 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase HATPase_c PF02518.26 PRP89050.1 - 1.4e-28 99.6 0.1 3.6e-28 98.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP89050.1 - 2.4e-26 92.1 0.1 2.4e-25 88.9 0.1 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 PRP89050.1 - 1.2e-15 57.2 0.0 7.3e-15 54.8 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 PRP89050.1 - 0.00043 20.5 0.0 0.007 16.6 0.0 2.9 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.10 PRP89050.1 - 0.0031 17.7 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold MFS_1 PF07690.16 PRP89052.1 - 2.2e-26 92.6 26.7 3e-26 92.2 26.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP89052.1 - 3.7e-15 55.8 5.7 3.7e-15 55.8 5.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 PRP89052.1 - 0.0028 16.6 9.7 0.0028 16.6 9.7 2.5 1 1 1 3 3 3 1 MFS_1 like family MFS_3 PF05977.13 PRP89052.1 - 0.012 14.0 2.4 0.018 13.5 2.4 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector CTP_transf_like PF01467.26 PRP89053.1 - 3.8e-15 56.3 0.0 7e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like GH-E PF14410.6 PRP89053.1 - 0.038 14.4 0.2 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues PTR2 PF00854.21 PRP89054.1 - 5.6e-102 341.5 8.7 1.4e-101 340.2 8.7 1.6 1 0 0 1 1 1 1 POT family DUF2046 PF09755.9 PRP89054.1 - 3.5e-12 46.2 43.3 3.1e-11 43.1 43.3 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) BK_channel_a PF03493.18 PRP89056.1 - 1.9e-18 66.4 0.0 8.4e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PRP89056.1 - 1.6e-14 53.6 3.2 1.6e-14 53.6 3.2 3.2 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 PRP89056.1 - 4.9e-06 26.0 13.4 4.9e-06 26.0 13.4 2.2 1 1 1 2 2 2 1 Ion transport protein TrkA_N PF02254.18 PRP89056.1 - 9.4e-05 22.7 0.0 0.00046 20.4 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain tRNA_SAD PF07973.14 PRP89057.1 - 3.9e-05 23.6 0.1 7e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CdiI_N PF18228.1 PRP89057.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 CdiI N-terminal domain MFS_1 PF07690.16 PRP89058.1 - 1.2e-20 73.7 63.2 1.5e-09 37.3 19.1 3.5 2 1 1 4 4 4 4 Major Facilitator Superfamily Sugar_tr PF00083.24 PRP89058.1 - 0.0012 17.8 15.9 0.0012 17.8 15.9 3.8 4 1 0 4 4 4 1 Sugar (and other) transporter Holin_SPP1 PF04688.13 PRP89058.1 - 2.9 8.1 7.0 4.9 7.4 0.7 3.3 3 0 0 3 3 3 0 SPP1 phage holin TPR_2 PF07719.17 PRP89059.1 - 6.9e-12 44.5 0.2 0.00037 20.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP89059.1 - 1.1e-11 44.0 0.1 5.9e-05 22.7 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP89059.1 - 1e-08 34.7 0.0 0.005 17.0 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP89059.1 - 3.9e-08 33.3 0.2 0.00045 20.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 PRP89059.1 - 4.2e-07 30.2 0.6 0.0014 18.8 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP89059.1 - 7.4e-06 26.0 0.1 0.00043 20.5 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP89059.1 - 1.7e-05 24.4 0.6 0.0078 15.9 0.0 3.8 3 1 1 4 4 4 1 TPR repeat TPR_10 PF13374.6 PRP89059.1 - 0.00056 19.7 4.0 0.032 14.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat V-SNARE PF05008.15 PRP89059.1 - 0.0024 18.2 1.3 0.043 14.2 0.1 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus TPR_14 PF13428.6 PRP89059.1 - 0.015 16.0 1.4 46 5.2 0.0 3.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PRP89059.1 - 0.016 15.2 0.0 8.9 6.6 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP89059.1 - 0.018 15.7 0.0 1.1 10.0 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PRP89059.1 - 0.018 15.5 0.8 0.55 10.8 0.0 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 PRP89059.1 - 0.035 13.0 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 PRP89059.1 - 0.048 13.7 0.7 2.3 8.3 0.0 2.8 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) BORCS8 PF10167.9 PRP89059.1 - 0.074 13.0 1.7 4.6 7.2 0.0 2.6 1 1 2 3 3 3 0 BLOC-1-related complex sub-unit 8 TPR_6 PF13174.6 PRP89059.1 - 0.15 12.7 2.1 8.3 7.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 PRP89059.1 - 0.74 10.0 3.7 3.5 7.8 1.4 2.4 1 1 1 2 2 2 0 HemY protein N-terminus Pkinase PF00069.25 PRP89060.1 - 8e-61 205.7 0.0 1.1e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89060.1 - 7.9e-31 107.3 0.0 1.5e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP89060.1 - 9e-09 35.0 0.0 2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 PRP89060.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YqaJ PF09588.10 PRP89061.1 - 1.6e-26 93.2 1.5 1.7e-26 93.2 0.3 1.6 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain TatD_DNase PF01026.21 PRP89062.1 - 8.5e-41 140.0 0.0 1.6e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 TatD related DNase MS_channel PF00924.18 PRP89063.1 - 6.6e-19 68.3 0.7 1.3e-18 67.3 0.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 PRP89063.1 - 1.9e-09 36.4 0.3 1.5e-06 27.3 0.0 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PRP89063.1 - 2.4e-07 30.1 0.2 9e-05 22.1 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 PRP89063.1 - 3.7e-06 27.3 1.9 0.0019 18.6 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP89063.1 - 5.9e-06 25.5 0.1 0.0018 17.7 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PRP89063.1 - 0.027 14.3 0.7 0.61 10.0 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain pair GxGYxYP_N PF16216.5 PRP89063.1 - 0.19 11.9 0.9 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 GxGYxY sequence motif in domain of unknown function N-terminal Pro-kuma_activ PF09286.11 PRP89064.1 - 2.7e-22 79.6 0.0 5.2e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP89064.1 - 0.00071 18.9 0.0 0.0033 16.7 0.0 1.8 1 1 0 1 1 1 1 Subtilase family Mad3_BUB1_I PF08311.12 PRP89065.1 - 5e-43 146.0 3.1 9.3e-43 145.2 3.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 PRP89065.1 - 3.2e-17 62.8 0.1 5.5e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PRP89065.1 - 2.5e-05 23.8 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Mad3_BUB1_I_2 PF17014.5 PRP89065.1 - 0.0027 17.8 0.7 0.0078 16.3 0.7 1.7 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein NRDE-2 PF08424.10 PRP89065.1 - 0.0093 15.1 2.5 0.021 13.9 1.8 1.8 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference Kdo PF06293.14 PRP89065.1 - 0.14 11.5 1.4 0.55 9.6 0.5 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP89065.1 - 1.7 8.2 5.2 1 8.9 0.7 2.6 3 0 0 3 3 3 0 RIO1 family SYF2 PF08231.12 PRP89066.1 - 1.4e-30 106.8 18.7 1.4e-30 106.8 18.7 2.1 1 1 1 2 2 2 1 SYF2 splicing factor NYN PF01936.18 PRP89068.1 - 0.022 15.2 0.0 0.057 13.9 0.0 1.7 1 1 1 2 2 2 0 NYN domain DUF3886 PF13025.6 PRP89070.1 - 2.1 8.6 13.9 4.1 7.7 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) TMEM154 PF15102.6 PRP89076.1 - 0.0017 18.3 0.5 0.0034 17.3 0.5 1.4 1 0 0 1 1 1 1 TMEM154 protein family Dioxygenase_C PF00775.21 PRP89076.1 - 0.016 14.6 0.2 0.055 12.9 0.0 1.9 2 1 0 2 2 2 0 Dioxygenase Glycophorin_A PF01102.18 PRP89076.1 - 0.036 14.3 1.0 0.1 12.9 1.0 1.7 1 0 0 1 1 1 0 Glycophorin A AsmA PF05170.14 PRP89076.1 - 0.066 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 AsmA family DFP PF04127.15 PRP89077.1 - 6.5e-17 62.0 0.0 4.7e-10 39.6 0.0 2.4 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RHH_3 PF12651.7 PRP89077.1 - 0.0043 17.0 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 Ribbon-helix-helix domain DENN PF02141.21 PRP89078.1 - 4.2e-25 88.8 0.9 1.1e-24 87.4 0.9 1.7 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 PRP89078.1 - 0.00048 20.8 0.0 0.0014 19.4 0.0 1.8 1 0 0 1 1 1 1 uDENN domain SPA PF08616.10 PRP89078.1 - 0.14 12.1 0.4 0.37 10.7 0.1 1.8 2 0 0 2 2 2 0 Stabilization of polarity axis RabGAP-TBC PF00566.18 PRP89079.1 - 4.7e-41 140.8 0.5 6.3e-41 140.4 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Na_H_Exchanger PF00999.21 PRP89080.1 - 1.5e-40 139.1 38.1 2.2e-40 138.6 38.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Fst_toxin PF13955.6 PRP89080.1 - 0.0044 16.9 2.9 0.022 14.7 2.9 2.3 1 0 0 1 1 1 1 Toxin Fst, type I toxin-antitoxin system DUF3852 PF12963.7 PRP89080.1 - 0.011 16.0 8.3 0.49 10.7 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3852) Chromo PF00385.24 PRP89081.1 - 1.8e-11 43.7 2.9 3.9e-11 42.7 2.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HhH-GPD PF00730.25 PRP89081.1 - 4e-05 24.0 0.0 6.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF1283 PF06932.11 PRP89081.1 - 2.1 8.6 7.5 10 6.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) PAP2_C PF14360.6 PRP89083.1 - 4.5e-25 88.0 4.1 4.5e-25 88.0 4.1 2.8 3 0 0 3 3 3 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 PRP89083.1 - 5.3e-07 30.0 0.1 1.1e-06 29.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2_3 PF14378.6 PRP89083.1 - 9.9e-07 28.6 3.7 9.9e-07 28.6 3.7 2.6 1 1 2 3 3 3 1 PAP2 superfamily SAM_2 PF07647.17 PRP89083.1 - 2.9e-06 27.3 0.0 6.7e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 PRP89083.1 - 0.00069 19.4 4.6 0.00069 19.4 4.6 2.3 1 1 1 2 2 2 1 PAP2 superfamily SAM_PNT PF02198.16 PRP89083.1 - 0.0013 18.6 0.0 0.0062 16.5 0.0 2.2 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain DUF4131 PF13567.6 PRP89083.1 - 0.34 10.6 2.6 0.94 9.1 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF656 PF04920.12 PRP89083.1 - 0.46 10.4 2.3 19 5.2 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF656) DUF4224 PF13986.6 PRP89084.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) FAD_binding_3 PF01494.19 PRP89085.1 - 1.1e-27 97.2 0.7 3.3e-27 95.6 0.1 2.0 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 PRP89085.1 - 1.9e-14 54.0 0.7 4.8e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PRP89085.1 - 4.7e-11 42.5 0.8 0.00019 20.7 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP89085.1 - 6.4e-11 42.7 0.1 1e-06 29.2 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP89085.1 - 1e-08 34.3 0.6 0.00014 20.7 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 PRP89085.1 - 1.9e-07 30.5 0.2 3.2e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 PRP89085.1 - 2.2e-07 31.0 0.1 5.4e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 PRP89085.1 - 4.8e-06 25.7 1.2 0.0029 16.5 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 PRP89085.1 - 9.3e-06 25.0 1.6 1.9e-05 23.9 0.4 2.0 1 1 1 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 PRP89085.1 - 1.2e-05 24.9 0.9 0.097 11.9 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 PRP89085.1 - 1.7e-05 24.2 0.1 0.00031 20.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PRP89085.1 - 0.00016 20.9 0.4 0.0003 20.0 0.4 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 PRP89085.1 - 0.0013 18.0 0.4 0.0036 16.6 0.3 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 PRP89085.1 - 0.013 15.5 0.2 0.34 10.9 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 PRP89085.1 - 0.015 14.6 0.1 0.034 13.5 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1188 PF06690.11 PRP89085.1 - 0.019 14.5 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) Shikimate_DH PF01488.20 PRP89085.1 - 0.032 14.3 0.1 0.093 12.8 0.1 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 PRP89085.1 - 0.039 13.8 0.3 0.076 12.9 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 PRP89085.1 - 0.059 13.8 0.2 0.15 12.5 0.2 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 PRP89085.1 - 0.085 12.5 0.2 0.21 11.2 0.2 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 PRP89085.1 - 0.5 9.6 6.0 0.17 11.2 0.4 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase DSPc PF00782.20 PRP89086.1 - 2e-27 95.6 0.1 2e-27 95.6 0.1 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain GDP_Man_Dehyd PF16363.5 PRP89087.1 - 1.3e-59 202.3 0.0 1.6e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PRP89087.1 - 9e-50 169.4 0.1 1.1e-49 169.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PRP89087.1 - 3.6e-19 69.0 0.5 1.9e-17 63.4 0.2 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 PRP89087.1 - 1.1e-17 64.0 0.3 3.9e-17 62.2 0.3 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PRP89087.1 - 1.7e-14 53.6 0.0 4.9e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PRP89087.1 - 3.6e-12 46.0 1.9 7.1e-11 41.8 1.9 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 PRP89087.1 - 1.7e-07 31.4 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP89087.1 - 1e-06 28.8 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PRP89087.1 - 0.0019 17.8 0.1 0.0067 16.0 0.1 2.0 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 PRP89087.1 - 0.0043 16.5 0.1 0.011 15.2 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 PRP89087.1 - 0.089 12.4 1.1 0.22 11.1 1.1 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ras PF00071.22 PRP89088.1 - 2.2e-48 163.9 0.0 1.1e-47 161.7 0.0 2.0 2 0 0 2 2 2 1 Ras family Roc PF08477.13 PRP89088.1 - 5.7e-15 55.6 0.0 2.1e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89088.1 - 1.2e-08 34.6 0.0 2.2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family CRT10 PF08728.10 PRP89088.1 - 9.4e-05 20.8 0.1 0.03 12.5 0.1 2.4 3 0 0 3 3 3 2 CRT10 WD40 PF00400.32 PRP89088.1 - 0.00044 21.0 0.5 0.00044 21.0 0.5 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat GTP_EFTU PF00009.27 PRP89088.1 - 0.0081 15.7 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP89088.1 - 0.095 12.6 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase OTU PF02338.19 PRP89089.1 - 9.2e-22 77.9 1.6 2e-21 76.8 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease BcrAD_BadFG PF01869.20 PRP89089.1 - 0.037 13.5 0.4 0.18 11.3 0.3 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_C65 PF10275.9 PRP89089.1 - 0.17 11.3 10.6 0.57 9.6 0.2 3.0 2 1 1 3 3 3 0 Peptidase C65 Otubain CRAL_TRIO PF00650.20 PRP89091.1 - 3.3e-19 69.2 0.0 4.6e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain LIP1 PF15904.5 PRP89091.1 - 0.078 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 DUF4698 PF15769.5 PRP89092.1 - 2.1 7.3 3.8 3 6.8 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) RIFIN PF02009.16 PRP89092.1 - 3.3 7.5 6.5 4 7.2 6.5 1.1 1 0 0 1 1 1 0 Rifin Pkinase PF00069.25 PRP89093.1 - 3.1e-60 203.8 0.0 9.1e-60 202.2 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89093.1 - 1.8e-33 116.0 0.0 3.7e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 PRP89093.1 - 7.9e-06 26.2 0.7 0.11 12.9 0.0 4.2 3 1 0 3 3 3 2 HEAT repeats Kinase-like PF14531.6 PRP89093.1 - 1.4e-05 24.6 0.0 3.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Arm PF00514.23 PRP89093.1 - 9.5e-05 22.3 4.2 0.22 11.6 0.1 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 PRP89093.1 - 0.0046 17.1 0.0 11 6.2 0.1 4.2 4 0 0 4 4 4 1 V-ATPase subunit H HEAT PF02985.22 PRP89093.1 - 0.0083 16.3 7.2 2.8 8.5 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat DUF1981 PF09324.10 PRP89093.1 - 0.024 14.5 0.6 2.6 8.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) HEAT_EZ PF13513.6 PRP89093.1 - 0.062 13.8 1.6 19 5.9 0.0 4.1 4 1 1 5 5 5 0 HEAT-like repeat Sdh5 PF03937.16 PRP89094.1 - 3.3e-15 55.8 0.3 4.8e-15 55.3 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase MetRS-N PF09635.10 PRP89094.1 - 0.017 15.6 0.0 0.84 10.2 0.0 2.0 1 1 1 2 2 2 0 MetRS-N binding domain PPR_2 PF13041.6 PRP89095.1 - 2.9e-09 37.0 1.3 0.00074 19.7 0.0 5.0 4 1 2 6 6 6 2 PPR repeat family PPR_3 PF13812.6 PRP89095.1 - 0.00019 21.5 0.0 0.5 10.5 0.0 3.6 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 PRP89095.1 - 0.00029 20.9 3.3 0.41 11.0 0.0 5.7 7 0 0 7 7 7 1 PPR repeat PPR_long PF17177.4 PRP89095.1 - 0.00063 19.2 0.0 0.0045 16.4 0.0 2.1 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP CBX7_C PF17218.3 PRP89095.1 - 0.0021 17.8 0.1 3 7.7 0.0 2.6 2 0 0 2 2 2 2 CBX family C-terminal motif PEPcase PF00311.17 PRP89098.1 - 0.0015 16.7 1.6 0.0019 16.4 1.6 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase SICA_alpha PF12887.7 PRP89098.1 - 0.0085 16.0 0.3 0.011 15.7 0.3 1.1 1 0 0 1 1 1 1 SICA extracellular alpha domain Herpes_UL6 PF01763.16 PRP89098.1 - 0.024 13.2 0.5 0.025 13.1 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CdiI_2 PF18593.1 PRP89098.1 - 0.028 15.1 0.2 0.044 14.4 0.2 1.3 1 0 0 1 1 1 0 CdiI immunity protein DNA_pol_B PF00136.21 PRP89098.1 - 0.039 12.7 0.3 0.046 12.4 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase family B GAS PF13851.6 PRP89098.1 - 0.049 13.0 5.7 0.071 12.5 5.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lipoprotein_7 PF01540.16 PRP89098.1 - 0.065 12.5 2.4 0.13 11.6 2.4 1.4 1 1 1 2 2 2 0 Adhesin lipoprotein V_ATPase_I PF01496.19 PRP89098.1 - 0.26 9.1 1.9 0.29 9.0 1.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 PRP89098.1 - 0.39 11.4 4.6 0.6 10.8 4.6 1.2 1 0 0 1 1 1 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 PRP89098.1 - 0.7 10.1 8.3 0.32 11.2 3.3 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TFIIS_C PF01096.18 PRP89099.1 - 1.9e-09 37.2 9.2 3.8e-09 36.2 5.2 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Ogr_Delta PF04606.12 PRP89099.1 - 0.66 10.0 6.7 0.89 9.6 3.8 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger RNA_pol_Rpc4 PF05132.14 PRP89100.1 - 3.3e-17 63.3 3.8 4.4e-17 62.9 1.0 2.4 1 1 1 2 2 2 2 RNA polymerase III RPC4 RRF PF01765.19 PRP89100.1 - 0.26 11.2 2.6 0.57 10.1 0.9 2.2 2 1 1 3 3 3 0 Ribosome recycling factor Pkinase_Tyr PF07714.17 PRP89101.1 - 1.9e-65 220.7 0.0 3e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89101.1 - 7.9e-44 150.0 0.0 1.2e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP89101.1 - 1.8e-34 117.3 95.3 7.4e-10 38.4 5.1 13.8 10 3 5 15 15 15 12 Leucine rich repeat LRR_4 PF12799.7 PRP89101.1 - 7.4e-28 96.2 95.4 0.0029 18.0 1.0 16.9 7 4 13 21 21 21 16 Leucine Rich repeats (2 copies) Cellulase PF00150.18 PRP89101.1 - 9.9e-19 67.8 21.5 2.4e-11 43.6 1.8 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Kinase-like PF14531.6 PRP89101.1 - 8.6e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP89101.1 - 0.089 11.6 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PRP89101.1 - 0.21 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 PRP89101.1 - 8.6 6.7 53.1 12 6.3 0.0 15.1 19 0 0 19 19 19 0 Leucine Rich repeat WD40 PF00400.32 PRP89103.1 - 8.4e-09 35.9 7.3 0.047 14.6 0.1 5.7 5 2 0 5 5 4 2 WD domain, G-beta repeat zf-C3HC4_3 PF13920.6 PRP89103.1 - 2.5e-08 33.6 6.5 5.3e-08 32.6 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) F-box PF00646.33 PRP89103.1 - 3.1e-07 30.1 1.8 7.7e-07 28.8 1.8 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PRP89103.1 - 3.9e-07 29.9 0.3 7.3e-07 29.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like zf-C3HC4_2 PF13923.6 PRP89103.1 - 4.9e-06 26.3 10.8 1.1e-05 25.1 10.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP89103.1 - 5.9e-06 26.1 7.6 1.4e-05 24.8 7.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PRP89103.1 - 9.5e-06 25.5 7.2 0.00014 21.8 6.5 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PRP89103.1 - 1.1e-05 25.2 10.3 2.3e-05 24.2 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 PRP89103.1 - 2.2e-05 24.7 0.3 1.3 9.4 0.2 4.0 3 2 0 3 3 2 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 PRP89103.1 - 7.3e-05 22.6 10.5 0.00016 21.6 10.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PRP89103.1 - 0.00016 21.8 9.5 0.001 19.2 9.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 PRP89103.1 - 0.00084 19.4 3.9 0.0022 18.1 3.9 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 WD40_like PF17005.5 PRP89103.1 - 0.0036 16.7 0.2 1.5 8.1 0.0 3.1 2 1 0 2 2 2 1 WD40-like domain zf-RING_2 PF13639.6 PRP89103.1 - 0.0062 16.8 10.7 0.0062 16.8 10.7 1.9 2 0 0 2 2 2 1 Ring finger domain CPSF_A PF03178.15 PRP89103.1 - 0.025 13.9 0.2 4.3 6.6 0.1 2.6 3 0 0 3 3 3 0 CPSF A subunit region PQQ PF01011.21 PRP89103.1 - 0.027 14.4 1.1 0.38 10.8 0.0 3.2 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_2 PF13360.6 PRP89103.1 - 0.033 13.8 0.0 1.3 8.6 0.0 2.7 1 1 1 2 2 2 0 PQQ-like domain Coatomer_WDAD PF04053.14 PRP89103.1 - 0.093 11.8 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region zf-P11 PF03854.14 PRP89103.1 - 0.3 10.8 5.5 0.77 9.5 5.5 1.7 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 PRP89103.1 - 2.1 8.4 6.9 4.6 7.4 6.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon Homeodomain PF00046.29 PRP89105.1 - 1.7e-17 63.0 5.7 2.4e-17 62.5 5.7 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP89105.1 - 2.3e-07 30.6 1.3 3.7e-07 29.9 1.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain CENP-B_N PF04218.13 PRP89105.1 - 0.0029 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain BrkDBD PF09607.10 PRP89105.1 - 0.041 13.7 1.5 0.041 13.7 1.5 1.9 2 1 0 2 2 2 0 Brinker DNA-binding domain Peptidase_M16_C PF05193.21 PRP89106.1 - 7.4e-57 192.3 0.0 4.1e-34 118.2 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Cyclin_N PF00134.23 PRP89106.1 - 7e-33 113.1 0.6 1.6e-32 111.9 0.6 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Peptidase_M16 PF00675.20 PRP89106.1 - 2.1e-23 83.0 0.1 4.8e-12 46.1 0.3 2.6 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 PRP89106.1 - 0.09 11.9 0.3 0.4 9.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase M16C associated Ig_GlcNase PF18368.1 PRP89106.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain DBR1 PF05011.13 PRP89108.1 - 1.5e-20 74.0 0.1 3.9e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 PRP89108.1 - 1.7e-08 35.2 1.0 2.6e-08 34.6 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pro-kuma_activ PF09286.11 PRP89109.1 - 1.8e-28 99.6 0.3 2.2e-28 99.4 0.3 1.1 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain LTXXQ PF07813.12 PRP89109.1 - 0.049 14.3 0.5 0.076 13.7 0.5 1.3 1 0 0 1 1 1 0 LTXXQ motif family protein PKcGMP_CC PF16808.5 PRP89109.1 - 0.079 12.8 1.2 15 5.5 1.8 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RNase_H PF00075.24 PRP89109.1 - 0.15 12.3 0.8 0.24 11.6 0.8 1.5 1 1 0 1 1 1 0 RNase H DSPc PF00782.20 PRP89110.1 - 6.4e-32 110.2 0.1 1.3e-31 109.2 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain EamA PF00892.20 PRP89110.1 - 4.3e-19 69.0 31.3 9.4e-15 55.0 12.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family AP_endonuc_2 PF01261.24 PRP89110.1 - 1.4e-14 54.1 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel PUNUT PF16913.5 PRP89110.1 - 6.7e-06 25.5 0.4 1.3e-05 24.6 0.4 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TMEM234 PF10639.9 PRP89110.1 - 7.6e-05 22.7 0.1 0.00032 20.7 0.1 2.1 1 0 0 1 1 1 1 Putative transmembrane family 234 Y_phosphatase PF00102.27 PRP89110.1 - 0.00061 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase TPT PF03151.16 PRP89110.1 - 0.0013 18.1 2.5 0.0024 17.3 2.5 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family Porin_3 PF01459.22 PRP89111.1 - 3.9e-16 59.3 0.0 4.5e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin TTL PF03133.15 PRP89112.1 - 1.1e-83 280.8 1.0 1.1e-83 280.8 1.0 1.5 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PRP89112.1 - 0.0001 21.6 3.2 0.061 12.6 0.0 3.5 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PRP89112.1 - 0.0023 17.3 0.0 0.46 9.7 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 PRP89112.1 - 0.12 11.9 0.0 0.53 9.8 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Flavin_Reduct PF01613.18 PRP89113.1 - 9.5e-13 48.5 0.0 1.3e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Pkinase_Tyr PF07714.17 PRP89114.1 - 2.3e-66 223.8 0.5 3.4e-66 223.2 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP89114.1 - 1.2e-53 178.7 88.9 1.9e-09 37.1 4.2 15.9 8 4 8 18 18 18 18 Leucine rich repeat Pkinase PF00069.25 PRP89114.1 - 8.6e-43 146.6 0.2 1.3e-42 146.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP89114.1 - 2.2e-34 116.9 104.5 3.7e-06 27.2 2.4 19.1 10 5 12 23 23 23 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP89114.1 - 3e-10 39.2 90.0 0.41 11.4 0.0 25.8 28 4 0 28 28 25 3 Leucine Rich Repeat Kinase-like PF14531.6 PRP89114.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 PRP89114.1 - 0.018 14.6 0.2 0.034 13.8 0.2 1.3 1 0 0 1 1 1 0 RIO1 family Insulin_TMD PF17870.1 PRP89114.1 - 0.026 14.6 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Haspin_kinase PF12330.8 PRP89114.1 - 0.029 13.3 0.1 0.13 11.2 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PRP89114.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_6 PF13516.6 PRP89114.1 - 0.097 12.8 73.4 2.3 8.5 0.9 18.7 21 0 0 21 21 21 0 Leucine Rich repeat Pkinase_fungal PF17667.1 PRP89114.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PKD_channel PF08016.12 PRP89115.1 - 1.8e-27 96.1 3.5 2.6e-14 52.7 0.0 2.4 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 PRP89115.1 - 0.024 13.9 7.7 0.051 12.8 7.7 1.5 1 1 0 1 1 1 0 Ion transport protein DUF4430 PF14478.6 PRP89116.1 - 0.097 13.3 0.1 0.13 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) DUF1996 PF09362.10 PRP89117.1 - 3.9e-69 233.2 0.3 5.1e-69 232.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RicinB_lectin_2 PF14200.6 PRP89117.1 - 0.35 11.6 6.2 1.3 9.8 2.4 2.5 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Fra10Ac1 PF09725.9 PRP89118.1 - 6.9e-48 161.9 3.0 1.2e-47 161.1 3.0 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 UL41A PF17591.2 PRP89118.1 - 0.17 12.0 0.5 0.35 11.0 0.5 1.5 1 0 0 1 1 1 0 Herpesvirus UL41A PBP1_TM PF14812.6 PRP89118.1 - 3 8.3 12.3 0.8 10.1 4.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_47 PF01532.20 PRP89119.1 - 1e-149 499.4 0.0 1.3e-149 499.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DNA_pol3_chi PF04364.13 PRP89119.1 - 0.11 12.6 0.3 0.27 11.4 0.2 1.6 2 0 0 2 2 2 0 DNA polymerase III chi subunit, HolC Glyco_hydro_31 PF01055.26 PRP89120.1 - 2.3e-83 280.9 9.6 3.1e-83 280.4 9.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 PRP89120.1 - 3.2e-16 59.4 4.4 3.1e-15 56.2 0.3 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 PRP89120.1 - 0.029 14.7 0.7 0.12 12.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) Glyco_hydro_3_C PF01915.22 PRP89121.1 - 4.3e-49 167.3 0.0 1.4e-48 165.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PRP89121.1 - 5.3e-39 134.4 0.1 9.2e-39 133.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 PRP89121.1 - 1.1e-17 63.9 0.0 2.3e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ARTD15_N PF18084.1 PRP89122.1 - 3.2e-09 36.9 0.6 5.2e-09 36.2 0.1 1.6 2 0 0 2 2 2 1 ARTD15 N-terminal domain PARP PF00644.20 PRP89122.1 - 5.6e-08 32.6 0.4 1.3e-07 31.4 0.3 1.6 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain GYF PF02213.16 PRP89123.1 - 5e-11 42.1 5.3 1.4e-10 40.7 5.3 1.8 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 PRP89123.1 - 6.6e-09 35.4 1.4 1.1e-08 34.7 0.4 1.9 2 0 0 2 2 2 1 GYF domain 2 DnaJ PF00226.31 PRP89124.1 - 5.5e-07 29.6 0.1 1.1e-06 28.6 0.1 1.5 1 1 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 PRP89124.1 - 6.3e-05 23.0 0.0 9.9e-05 22.4 0.0 1.2 1 1 0 1 1 1 1 Pam16 RNA_pol_Rpb1_5 PF04998.17 PRP89125.1 - 6.5e-86 288.1 1.4 1.2e-85 287.2 1.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 PRP89125.1 - 5.7e-85 285.4 3.9 9.1e-85 284.7 3.9 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 PRP89125.1 - 1.1e-72 243.7 1.1 7.2e-72 241.0 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PRP89125.1 - 2e-38 131.8 3.0 1.1e-37 129.4 0.0 3.3 3 2 1 4 4 4 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PRP89125.1 - 1.9e-30 105.0 0.7 7.3e-30 103.1 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RhoGAP PF00620.27 PRP89126.1 - 6.4e-41 139.7 0.3 6.4e-41 139.7 0.3 6.8 8 2 2 11 11 11 1 RhoGAP domain DIL PF01843.19 PRP89126.1 - 5.8e-08 32.9 0.1 5.8e-08 32.9 0.1 4.8 4 2 0 4 4 4 1 DIL domain DUF4443 PF14544.6 PRP89126.1 - 0.00041 20.5 4.1 0.64 10.3 0.3 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4443) CENP-F_leu_zip PF10473.9 PRP89126.1 - 0.0014 18.6 34.0 0.0014 18.6 34.0 16.1 2 1 13 18 18 18 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase_Tyr PF07714.17 PRP89127.1 - 1.5e-23 83.4 1.0 2.8e-23 82.5 1.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89127.1 - 1.1e-18 67.5 0.5 1.8e-18 66.9 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain GPS PF01825.21 PRP89127.1 - 1.6e-08 35.0 3.9 4.6e-08 33.5 3.9 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP89127.1 - 2e-08 34.4 19.1 4.1e-05 23.9 0.9 3.8 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP89127.1 - 7.3e-07 28.9 13.6 0.0047 16.6 0.5 3.9 3 0 0 3 3 3 3 Leucine rich repeat TMEM154 PF15102.6 PRP89127.1 - 0.01 15.8 0.5 0.045 13.7 0.2 2.3 2 0 0 2 2 2 0 TMEM154 protein family PTS_EIIA_1 PF00358.20 PRP89127.1 - 0.087 12.6 0.1 12 5.7 0.1 2.4 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 LRR_6 PF13516.6 PRP89127.1 - 2.5 8.4 17.6 1.3 9.3 0.2 5.1 5 0 0 5 5 5 0 Leucine Rich repeat NAD_binding_10 PF13460.6 PRP89128.1 - 4.7e-09 36.4 0.0 3.2e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 PRP89128.1 - 3.8e-06 26.6 0.1 7.7e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PRP89128.1 - 5.2e-06 26.1 0.0 0.084 12.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 PRP89128.1 - 0.0016 18.5 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 PRP89128.1 - 0.0024 16.9 0.1 0.038 13.0 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 PRP89128.1 - 0.034 14.4 0.0 0.08 13.2 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_3 PF03447.16 PRP89128.1 - 0.071 13.8 0.0 0.15 12.7 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 PRP89128.1 - 0.071 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Closter_coat PF01785.17 PRP89129.1 - 0.065 12.5 0.2 0.085 12.1 0.2 1.1 1 0 0 1 1 1 0 Closterovirus coat protein ANAPC4_WD40 PF12894.7 PRP89130.1 - 1.3e-13 51.0 4.0 0.0034 17.6 0.0 7.5 2 2 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PRP89130.1 - 3.8e-09 36.7 4.3 0.0079 16.1 1.1 6.2 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 PRP89130.1 - 1.1e-07 32.4 20.6 7.9 7.5 1.5 7.8 6 2 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.12 PRP89130.1 - 0.001 18.9 5.8 3.1 7.8 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Oxidored-like PF09791.9 PRP89131.1 - 4.7e-11 42.2 5.0 8e-11 41.4 5.0 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal ProQ PF04352.13 PRP89131.1 - 0.0036 17.2 0.3 0.0046 16.8 0.3 1.1 1 0 0 1 1 1 1 ProQ/FINO family DUF5522 PF17653.1 PRP89131.1 - 0.11 12.5 4.2 0.2 11.6 4.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) PALP PF00291.25 PRP89132.1 - 8.1e-57 192.9 0.0 9.4e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MatP_C PF17414.2 PRP89133.1 - 0.088 13.0 3.4 2.4 8.4 0.1 3.5 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain PDCD7 PF16021.5 PRP89133.1 - 0.17 10.9 3.9 0.6 9.2 0.0 2.6 3 0 0 3 3 3 0 Programmed cell death protein 7 Ceramidase_alk PF04734.13 PRP89134.1 - 7.7e-207 687.9 0.0 9.7e-207 687.6 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Hist_deacetyl PF00850.19 PRP89134.1 - 1.5e-44 152.7 0.0 2.5e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Ceramidse_alk_C PF17048.5 PRP89134.1 - 3.8e-38 131.0 0.1 8.1e-38 129.9 0.1 1.6 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Peptidase_C1 PF00112.23 PRP89136.1 - 2.3e-45 155.4 0.4 4.8e-45 154.3 0.4 1.5 1 0 0 1 1 1 1 Papain family cysteine protease PAN_4 PF14295.6 PRP89136.1 - 3.3e-17 62.1 23.3 8.5e-10 38.4 6.3 3.0 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 PRP89136.1 - 6.1e-09 35.7 6.7 4.9e-05 23.2 0.3 2.8 3 0 0 3 3 3 2 PAN domain Inhibitor_I29 PF08246.12 PRP89136.1 - 1.4e-07 31.9 2.9 2.1e-07 31.2 2.9 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP89136.1 - 5e-05 22.3 1.6 0.0031 16.3 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family PAN_3 PF08277.12 PRP89136.1 - 0.016 15.0 8.5 0.11 12.3 0.7 2.7 2 0 0 2 2 2 0 PAN-like domain MANEC PF07502.14 PRP89136.1 - 0.14 12.4 8.6 1.3 9.3 1.5 2.6 2 0 0 2 2 2 0 MANEC domain PAN_2 PF08276.11 PRP89136.1 - 6.8 6.9 21.8 0.17 12.0 4.5 2.9 3 0 0 3 3 3 0 PAN-like domain ORC4_C PF14629.6 PRP89137.1 - 3.5e-13 49.4 0.0 6.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 PRP89137.1 - 5.7e-09 36.6 0.4 1.3e-08 35.4 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 PRP89137.1 - 5.7e-06 26.4 0.0 9.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 PRP89137.1 - 2e-05 25.0 0.1 0.0002 21.8 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PRP89137.1 - 4.5e-05 23.7 0.1 0.00013 22.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 PRP89137.1 - 6.8e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 PRP89137.1 - 0.0016 18.5 0.0 0.0037 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 PRP89137.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 PRP89137.1 - 0.006 16.1 0.0 0.023 14.2 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 PRP89137.1 - 0.0077 16.8 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 PRP89137.1 - 0.0099 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.14 PRP89137.1 - 0.014 15.3 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 PRP89137.1 - 0.06 13.3 0.1 0.55 10.1 0.0 2.3 2 1 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 PRP89137.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 NTPase MAD PF05557.13 PRP89139.1 - 0.0025 16.3 0.1 0.0044 15.5 0.1 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein Prefoldin_2 PF01920.20 PRP89139.1 - 0.11 12.5 0.9 0.2 11.6 0.9 1.5 1 0 0 1 1 1 0 Prefoldin subunit ADIP PF11559.8 PRP89139.1 - 3.2 7.8 7.5 0.23 11.6 1.7 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Ank_2 PF12796.7 PRP89140.1 - 3.1e-08 34.1 0.0 5.8e-06 26.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP89140.1 - 5.4e-08 32.5 0.2 0.0028 18.0 0.1 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 PRP89140.1 - 8.7e-07 29.1 0.0 0.00017 21.8 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PRP89140.1 - 1.9e-06 28.3 0.0 0.00015 22.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP89140.1 - 6.8e-06 26.3 0.4 0.00021 21.6 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeat RNA_pol_Rpc4 PF05132.14 PRP89140.1 - 2.6 8.5 14.1 27 5.2 11.9 3.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 WWE PF02825.20 PRP89142.1 - 1.6e-06 28.6 0.2 3.8e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 WWE domain Caldesmon PF02029.15 PRP89142.1 - 1.2e-05 24.3 34.5 1.7e-05 23.8 34.5 1.2 1 0 0 1 1 1 1 Caldesmon BRCT PF00533.26 PRP89142.1 - 7.5e-05 23.0 0.0 0.00036 20.8 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain CDC45 PF02724.14 PRP89142.1 - 0.0012 17.3 30.3 0.0018 16.7 30.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Dapper PF15268.6 PRP89142.1 - 0.0028 16.6 13.5 0.0032 16.4 13.5 1.1 1 0 0 1 1 1 1 Dapper VIR_N PF15912.5 PRP89142.1 - 0.0058 16.3 19.6 0.011 15.4 19.6 1.4 1 0 0 1 1 1 1 Virilizer, N-terminal Presenilin PF01080.17 PRP89142.1 - 0.011 14.6 19.9 0.015 14.1 19.9 1.2 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 PRP89142.1 - 0.025 13.1 35.8 0.039 12.5 35.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_15 PF13175.6 PRP89142.1 - 0.073 12.8 27.3 0.14 11.8 27.3 1.5 1 0 0 1 1 1 0 AAA ATPase domain SAPS PF04499.15 PRP89142.1 - 0.11 11.2 17.6 0.17 10.7 17.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MDM1 PF15501.6 PRP89142.1 - 0.15 11.2 29.9 0.22 10.6 29.9 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 SLC12 PF03522.15 PRP89142.1 - 0.27 10.2 22.3 0.45 9.5 22.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PTPRCAP PF15713.5 PRP89142.1 - 0.28 11.5 27.3 0.9 9.8 27.3 1.9 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SOBP PF15279.6 PRP89142.1 - 0.43 11.2 7.2 0.67 10.5 7.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein ASC PF00858.24 PRP89142.1 - 0.44 9.5 5.8 0.59 9.0 5.8 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel RR_TM4-6 PF06459.12 PRP89142.1 - 0.54 10.0 41.2 0.063 13.1 36.8 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2151 PF10221.9 PRP89142.1 - 1.1 7.8 21.2 1.7 7.1 21.2 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator GAGA_bind PF06217.12 PRP89142.1 - 1.4 9.1 25.2 2.6 8.2 25.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.22 PRP89142.1 - 1.6 7.9 17.7 2.4 7.3 17.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BORG_CEP PF14957.6 PRP89142.1 - 1.9 9.7 15.9 5.3 8.2 15.9 1.8 1 0 0 1 1 1 0 Cdc42 effector MDM10 PF12519.8 PRP89142.1 - 1.9 7.2 18.2 3.1 6.6 18.2 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 AAA_11 PF13086.6 PRP89142.1 - 3.1 7.5 21.1 6.5 6.5 21.1 1.5 1 0 0 1 1 1 0 AAA domain Band_3_cyto PF07565.13 PRP89142.1 - 4.2 7.1 18.9 7.5 6.3 18.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NPR3 PF03666.13 PRP89142.1 - 4.3 6.0 29.9 6.9 5.3 29.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDRGK PF09756.9 PRP89142.1 - 8 6.0 52.2 22 4.6 52.2 1.8 1 0 0 1 1 1 0 DDRGK domain UPF0121 PF03661.13 PRP89143.1 - 6.4e-30 104.3 9.1 8.6e-30 103.9 9.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CENP-B_dimeris PF09026.10 PRP89143.1 - 1 9.8 3.5 1.8 9.0 3.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4326 PF14216.6 PRP89144.1 - 2e-22 79.7 1.7 3.6e-22 78.9 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4326) UPF0242 PF06785.11 PRP89144.1 - 0.00029 21.0 0.8 0.00045 20.4 0.8 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DASH_Spc19 PF08287.11 PRP89144.1 - 0.015 15.2 2.6 0.026 14.4 2.6 1.3 1 0 0 1 1 1 0 Spc19 Zn_clus PF00172.18 PRP89146.1 - 8.6e-08 32.2 9.5 1.4e-07 31.5 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WW PF00397.26 PRP89147.1 - 3.2e-11 43.1 4.0 5.7e-11 42.3 4.0 1.4 1 0 0 1 1 1 1 WW domain Glyco_hydro_18 PF00704.28 PRP89148.1 - 2.2e-23 83.5 0.0 2.9e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_114 PF03537.13 PRP89148.1 - 0.077 12.3 0.5 0.37 10.1 0.5 2.0 1 1 0 1 1 1 0 Glycoside-hydrolase family GH114 N_BRCA1_IG PF16158.5 PRP89149.1 - 0.079 13.7 0.1 0.19 12.4 0.1 1.7 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene Sporozoite_P67 PF05642.11 PRP89149.1 - 1.3 7.0 10.0 1.6 6.7 10.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GFO_IDH_MocA PF01408.22 PRP89152.1 - 1.5e-17 64.6 0.0 3.2e-17 63.5 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 PRP89152.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain S-methyl_trans PF02574.16 PRP89153.1 - 1.6e-67 228.1 0.0 1.9e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Ank_2 PF12796.7 PRP89154.1 - 7.4e-69 228.4 2.3 5.5e-15 55.7 0.2 4.7 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP89154.1 - 1.3e-37 127.7 4.8 1.1e-09 38.7 0.1 7.4 1 1 7 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP89154.1 - 1.6e-36 120.1 0.5 3.9e-05 23.7 0.1 8.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 PRP89154.1 - 2.9e-30 103.9 0.8 3.7e-09 36.7 0.1 7.2 3 1 5 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 PRP89154.1 - 3.7e-28 96.7 5.5 0.00036 20.8 0.1 8.1 8 0 0 8 8 8 6 Ankyrin repeat Homeodomain PF00046.29 PRP89154.1 - 6.7e-18 64.3 1.6 1.3e-17 63.4 1.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP89154.1 - 0.023 14.6 0.2 0.069 13.1 0.2 1.8 1 0 0 1 1 1 0 Homeobox KN domain Carb_bind PF10645.9 PRP89156.1 - 0.00049 20.3 17.8 0.0037 17.4 14.5 2.5 1 1 1 2 2 2 2 Carbohydrate binding Mito_carr PF00153.27 PRP89157.1 - 3.7e-63 209.5 0.5 5.6e-20 71.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FYVE PF01363.21 PRP89161.1 - 1.3e-12 47.6 16.0 3.1e-12 46.5 16.0 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 PRP89161.1 - 3.6e-06 27.4 0.1 1.3e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 PH domain CCAP PF11105.8 PRP89161.1 - 2.1 8.3 6.6 0.67 9.9 0.1 2.4 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a PDEase_I PF00233.19 PRP89163.1 - 6.2e-83 278.2 10.3 6.2e-83 278.2 10.3 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase fn3 PF00041.21 PRP89163.1 - 0.0017 18.7 8.2 3.3 8.1 0.3 7.1 6 1 0 6 6 6 2 Fibronectin type III domain DUF4690 PF15756.5 PRP89163.1 - 0.0026 18.3 0.8 0.011 16.3 0.8 2.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage FMO-like PF00743.19 PRP89164.1 - 8.3e-21 74.0 0.1 2e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 PRP89164.1 - 5.3e-15 55.4 0.4 9.5e-12 44.7 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 PRP89164.1 - 7.2e-14 51.7 3.2 1.1e-08 34.7 0.3 3.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PRP89164.1 - 2.7e-13 49.8 0.2 1.2e-11 44.4 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PRP89164.1 - 1.8e-08 34.0 1.2 0.00014 21.2 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 PRP89164.1 - 2.5e-08 34.0 2.1 4.5e-08 33.2 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PRP89164.1 - 1.8e-06 27.8 6.5 3.2e-05 23.7 2.3 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PRP89164.1 - 2.1e-06 27.3 0.0 0.0088 15.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 PRP89164.1 - 6.7e-06 26.6 3.7 0.03 14.9 0.3 3.7 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP89164.1 - 3.5e-05 23.8 1.0 0.0038 17.2 0.1 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 PRP89164.1 - 0.00014 21.3 1.3 0.0027 17.1 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP89164.1 - 0.0017 17.1 3.9 0.0062 15.3 0.9 2.9 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 PRP89164.1 - 0.0046 17.4 0.1 1.7 9.1 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 PRP89164.1 - 0.0072 16.4 0.1 18 5.4 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 PRP89164.1 - 0.0082 15.3 0.7 0.0082 15.3 0.7 2.7 3 0 0 3 3 3 1 FAD binding domain 3HCDH_N PF02737.18 PRP89164.1 - 0.0096 15.8 0.3 0.021 14.7 0.3 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 PRP89164.1 - 0.028 13.7 3.6 0.15 11.3 0.4 2.9 3 0 0 3 3 3 0 Thi4 family NAD_binding_2 PF03446.15 PRP89164.1 - 0.11 12.7 0.1 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF5612 PF18462.1 PRP89164.1 - 0.11 12.2 0.4 0.55 10.0 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) GIDA PF01134.22 PRP89164.1 - 0.17 10.9 9.1 0.035 13.2 0.7 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A Actin PF00022.19 PRP89165.1 - 4.3e-81 272.6 0.0 9.2e-80 268.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PRP89165.1 - 0.00021 20.2 0.0 0.0006 18.7 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FAD_binding_3 PF01494.19 PRP89166.1 - 3.5e-06 26.5 0.1 0.23 10.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 PRP89166.1 - 0.00043 19.6 0.0 0.004 16.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP89166.1 - 0.0065 16.7 0.4 0.027 14.7 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Aa_trans PF01490.18 PRP89167.1 - 6.6e-61 206.2 24.6 7.9e-61 206.0 24.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 PRP89167.1 - 0.00051 19.2 12.3 0.00051 19.2 12.3 2.1 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family Mem_trans PF03547.18 PRP89167.1 - 0.25 9.7 9.1 0.26 9.6 0.1 3.0 2 1 0 2 2 2 0 Membrane transport protein RasGEF PF00617.19 PRP89168.1 - 5.9e-37 127.6 0.0 2e-36 125.9 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain zf-C2H2 PF00096.26 PRP89168.1 - 1.5e-10 40.9 46.4 0.025 15.0 3.9 7.1 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP89168.1 - 7e-06 26.5 41.6 0.03 15.1 1.9 6.8 6 0 0 6 6 6 5 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PRP89168.1 - 0.00058 20.1 17.7 0.14 12.5 0.4 4.2 1 1 1 3 3 3 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 PRP89168.1 - 0.0038 17.6 2.6 0.0038 17.6 2.6 5.8 5 0 0 5 5 5 2 Zinc-finger double domain RasGEF_N PF00618.20 PRP89168.1 - 0.09 13.0 2.1 0.12 12.6 0.1 2.3 2 0 0 2 2 2 0 RasGEF N-terminal motif PEHE PF15275.6 PRP89168.1 - 0.21 12.2 8.3 0.68 10.6 0.8 3.4 2 1 1 3 3 3 0 PEHE domain V4R PF02830.18 PRP89168.1 - 0.42 10.7 7.9 22 5.1 7.1 2.8 2 0 0 2 2 2 0 V4R domain zf-C2H2_jaz PF12171.8 PRP89168.1 - 0.55 10.6 12.5 12 6.3 0.2 4.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 PRP89168.1 - 0.81 10.4 25.0 0.81 10.4 0.1 6.1 3 2 4 7 7 7 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 PRP89168.1 - 2.9 7.9 5.8 0.68 9.9 1.8 2.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Med6 PF04934.14 PRP89169.1 - 8.4e-36 122.7 1.9 1.2e-35 122.3 1.9 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component TPR_14 PF13428.6 PRP89170.1 - 0.025 15.4 0.0 0.047 14.5 0.0 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S15 PF00312.22 PRP89170.1 - 0.033 14.4 0.6 0.037 14.2 0.6 1.2 1 0 0 1 1 1 0 Ribosomal protein S15 SH3_1 PF00018.28 PRP89171.1 - 8.6e-26 89.3 0.3 7e-12 44.8 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 PRP89171.1 - 2.6e-23 81.6 0.2 1.2e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 PRP89171.1 - 6e-20 70.7 0.0 3.5e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 PRP89171.1 - 8.2e-07 29.2 0.0 2.8e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain NPCBM PF08305.11 PRP89171.1 - 0.027 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 NPCBM/NEW2 domain DASH_Dad2 PF08654.10 PRP89171.1 - 0.033 14.6 0.8 0.23 11.9 0.7 2.6 2 1 0 2 2 2 0 DASH complex subunit Dad2 EMP24_GP25L PF01105.24 PRP89172.1 - 2.3e-50 171.1 0.0 2.7e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cellulase PF00150.18 PRP89173.1 - 1.1e-23 84.1 9.2 1.5e-23 83.6 9.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.6 PRP89173.1 - 0.00088 19.3 0.1 0.002 18.1 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Glyco_hydro_42 PF02449.15 PRP89173.1 - 0.007 15.7 1.2 3 7.1 0.1 2.8 2 1 1 3 3 3 2 Beta-galactosidase IF4E PF01652.18 PRP89174.1 - 2.9e-37 127.9 0.1 5.6e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Polysacc_lyase PF14099.6 PRP89174.1 - 6.7e-06 26.1 2.0 1.7e-05 24.8 2.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase LRR_4 PF12799.7 PRP89174.1 - 1e-05 25.8 14.0 0.027 14.9 0.2 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP89174.1 - 0.00038 20.3 10.6 0.01 15.8 0.1 4.9 4 0 0 4 4 4 1 Leucine Rich repeat NAM-associated PF14303.6 PRP89174.1 - 0.37 11.5 0.1 0.37 11.5 0.1 2.1 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain LRR_8 PF13855.6 PRP89174.1 - 0.72 9.7 12.1 1.1 9.1 1.4 3.5 1 1 2 3 3 3 0 Leucine rich repeat Tom37 PF10568.9 PRP89175.1 - 1.8e-07 31.5 0.0 3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 PRP89175.1 - 8.7e-07 29.6 0.0 3.2e-06 27.8 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 PRP89175.1 - 0.0082 15.9 0.1 0.021 14.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 PRP89177.1 - 4.3e-30 105.0 0.0 6.1e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89177.1 - 1.5e-24 86.7 0.0 2.2e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP89177.1 - 4.7e-06 26.1 0.0 7.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Oscp1 PF10188.9 PRP89178.1 - 1.2e-57 194.8 5.8 1.7e-57 194.4 5.8 1.2 1 0 0 1 1 1 1 Organic solute transport protein 1 Complex1_LYR PF05347.15 PRP89179.1 - 1.5e-05 24.9 0.0 2.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF2487 PF10673.9 PRP89179.1 - 0.029 14.4 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) SET PF00856.28 PRP89181.1 - 2.8e-10 40.9 0.0 1e-09 39.0 0.0 1.8 1 1 0 1 1 1 1 SET domain Dynactin_p22 PF07426.11 PRP89182.1 - 3.3e-29 101.9 0.1 4.1e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Parvo_coat PF00740.18 PRP89182.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Slu7 PF11708.8 PRP89183.1 - 0.002 17.9 1.3 0.0033 17.2 1.3 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor DUF4250 PF14056.6 PRP89183.1 - 0.13 12.3 0.3 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) DDHD PF02862.17 PRP89185.1 - 0.088 13.0 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 DDHD domain Ank_2 PF12796.7 PRP89187.1 - 5.1e-45 152.0 19.7 1.6e-12 47.8 1.0 7.6 4 2 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP89187.1 - 1.8e-40 136.8 9.0 6.7e-10 39.3 0.1 10.1 6 2 4 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP89187.1 - 6.5e-36 118.3 1.1 8.3e-05 22.7 0.0 11.9 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 PRP89187.1 - 2.1e-29 100.7 8.4 0.00014 22.1 0.0 10.5 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 PRP89187.1 - 2.8e-26 91.2 10.9 1.1e-07 32.0 0.1 8.8 7 3 2 9 9 9 5 Ankyrin repeats (many copies) Get5_C PF18514.1 PRP89187.1 - 0.021 14.6 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 0 Get5 C-terminal domain UFC1 PF08694.11 PRP89188.1 - 2.8e-81 270.7 0.1 3.2e-81 270.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 PRP89188.1 - 1.8e-05 24.4 0.2 9.2e-05 22.1 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme PNK3P PF08645.11 PRP89190.1 - 6.6e-55 185.2 0.1 1.3e-54 184.3 0.1 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase FHA_2 PF17913.1 PRP89190.1 - 2.5e-07 30.8 0.0 4.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain WH2 PF02205.20 PRP89190.1 - 2.6e-07 30.2 2.3 3.5e-07 29.8 0.7 2.2 2 0 0 2 2 2 1 WH2 motif AAA_33 PF13671.6 PRP89190.1 - 3.8e-06 27.1 0.4 0.049 13.8 0.0 3.4 2 1 1 3 3 3 2 AAA domain Hydrolase PF00702.26 PRP89190.1 - 0.012 15.9 1.4 1.2 9.4 0.0 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PRP89190.1 - 0.022 14.9 1.9 0.24 11.4 0.1 2.3 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_22 PF13401.6 PRP89190.1 - 0.024 14.9 0.1 0.17 12.1 0.0 2.3 3 0 0 3 3 3 0 AAA domain Hydrolase_6 PF13344.6 PRP89190.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NB-ARC PF00931.22 PRP89190.1 - 0.11 11.7 0.1 0.68 9.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Reticulon PF02453.17 PRP89192.1 - 5.5e-31 107.7 2.4 8.4e-31 107.1 2.4 1.3 1 0 0 1 1 1 1 Reticulon RhoGEF PF00621.20 PRP89194.1 - 1.1e-27 97.4 0.1 2.2e-27 96.5 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain F-box-like PF12937.7 PRP89195.1 - 5.6e-05 22.9 0.9 0.0003 20.6 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PRP89195.1 - 0.012 15.4 0.1 0.034 14.1 0.1 1.7 1 0 0 1 1 1 0 F-box domain PKD_channel PF08016.12 PRP89196.1 - 3.3e-41 141.3 5.0 5e-41 140.8 5.0 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 PRP89196.1 - 3e-06 26.7 20.6 5.3e-06 25.8 20.6 1.3 1 0 0 1 1 1 1 Ion transport protein Thaumatin PF00314.17 PRP89197.1 - 2.2e-13 50.3 11.2 5.3e-12 45.8 11.2 2.1 1 1 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 PRP89197.1 - 0.024 13.9 0.1 4.6 6.4 0.0 2.7 3 0 0 3 3 3 0 Beta-1,3-glucanase SpoIIID PF12116.8 PRP89198.1 - 0.089 12.9 2.3 14 5.9 0.0 3.1 2 1 1 3 3 3 0 Stage III sporulation protein D Fes1 PF08609.10 PRP89199.1 - 1.7e-13 51.3 0.9 9.6e-13 48.8 0.2 2.5 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 PRP89199.1 - 0.022 15.3 0.1 0.72 10.4 0.1 2.7 2 0 0 2 2 2 0 HEAT-like repeat MOR2-PAG1_C PF14225.6 PRP89199.1 - 0.058 13.3 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Cell morphogenesis C-terminal Tti2 PF10521.9 PRP89199.1 - 0.13 11.8 0.1 0.28 10.7 0.1 1.6 1 0 0 1 1 1 0 Tti2 family RGCC PF15151.6 PRP89200.1 - 1.5 9.1 6.1 2.6 8.3 6.1 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family Zn_clus PF00172.18 PRP89202.1 - 0.0046 17.1 3.2 0.0088 16.2 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PknH_C PF14032.6 PRP89202.1 - 0.053 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 PknH-like extracellular domain zf-RING_2 PF13639.6 PRP89207.1 - 1.2e-07 31.9 12.0 2.4e-07 30.9 12.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP89207.1 - 1.9e-06 27.6 11.9 4e-06 26.6 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP89207.1 - 4.7e-06 26.4 12.0 8.8e-06 25.5 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP89207.1 - 2.3e-05 24.3 11.1 4.7e-05 23.2 11.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PRP89207.1 - 2.4e-05 24.1 10.6 4.2e-05 23.3 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP89207.1 - 0.00058 20.1 11.6 0.0022 18.2 11.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PRP89207.1 - 0.0033 17.4 6.5 0.0033 17.4 6.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 PRP89207.1 - 0.0092 15.8 6.6 0.021 14.7 6.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 PRP89207.1 - 0.018 14.9 14.3 0.04 13.8 14.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GF_recep_IV PF14843.6 PRP89207.1 - 0.023 14.5 9.6 0.033 14.0 9.6 1.2 1 0 0 1 1 1 0 Growth factor receptor domain IV zf-ANAPC11 PF12861.7 PRP89207.1 - 0.18 11.8 7.1 1.1 9.3 7.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PRP89207.1 - 1.2 9.3 12.1 3.6 7.8 12.1 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Hamartin PF04388.12 PRP89208.1 - 2.3e-21 76.2 8.3 8e-19 67.8 1.9 3.8 3 1 0 4 4 4 2 Hamartin protein DUF4760 PF15956.5 PRP89208.1 - 0.023 14.8 0.3 0.023 14.8 0.3 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4760) Glyco_hydro_16 PF00722.21 PRP89209.1 - 7e-12 45.2 0.3 1e-11 44.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ist1 PF03398.14 PRP89210.1 - 8.2e-26 90.9 2.3 2.3e-25 89.4 0.1 2.7 2 1 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway TLD PF07534.16 PRP89210.1 - 1.9e-20 73.5 0.4 4.6e-20 72.3 0.4 1.7 1 0 0 1 1 1 1 TLD FYVE PF01363.21 PRP89210.1 - 8.5e-19 67.5 7.6 1.8e-18 66.4 7.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger OB_RNB PF08206.11 PRP89210.1 - 0.015 15.0 4.2 12 5.7 0.0 3.7 3 0 0 3 3 3 0 Ribonuclease B OB domain CSD2 PF17876.1 PRP89210.1 - 0.22 11.7 1.4 5.1 7.4 0.1 3.2 2 1 1 3 3 3 0 Cold shock domain Syntaxin_2 PF14523.6 PRP89210.1 - 0.43 11.0 9.9 0.074 13.4 0.6 3.2 3 0 0 3 3 3 0 Syntaxin-like protein RsbRD_N PF14361.6 PRP89210.1 - 2.4 8.9 4.2 1.6 9.4 0.6 2.6 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Gly-zipper_Omp PF13488.6 PRP89210.1 - 9.2 6.4 15.1 7.3 6.7 11.6 2.5 2 1 0 2 2 2 0 Glycine zipper Na_Ca_ex PF01699.24 PRP89211.1 - 4.8e-16 59.1 35.3 1.1e-10 41.7 15.0 2.6 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Linker_histone PF00538.19 PRP89211.1 - 2e-08 34.4 0.2 4.3e-08 33.4 0.2 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF3899 PF13038.6 PRP89211.1 - 0.013 16.0 1.8 0.028 14.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF4131 PF13567.6 PRP89211.1 - 0.1 12.2 0.1 2.9 7.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1264 PF06884.11 PRP89212.1 - 5.1e-65 218.2 0.5 6.4e-65 217.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TPR_12 PF13424.6 PRP89213.1 - 1.4e-23 83.0 25.3 4.2e-07 30.2 0.5 4.5 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 PRP89213.1 - 9e-16 56.7 10.2 6.4e-06 25.9 0.3 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 PRP89213.1 - 1.1e-15 56.7 10.9 0.00013 21.6 0.4 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 PRP89213.1 - 2.6e-11 42.8 9.2 0.017 15.3 0.1 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 PRP89213.1 - 1.2e-10 40.9 9.9 0.023 14.6 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat zf-MYND PF01753.18 PRP89213.1 - 3e-08 33.6 8.2 5.6e-08 32.7 8.2 1.5 1 0 0 1 1 1 1 MYND finger TPR_7 PF13176.6 PRP89213.1 - 1.4e-07 31.0 10.3 0.37 10.9 0.1 5.9 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP89213.1 - 7.9e-06 25.5 5.8 0.025 14.3 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 PRP89213.1 - 2.2e-05 24.9 2.4 1.1 10.3 0.0 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 PRP89213.1 - 3.3e-05 24.5 5.3 7 7.4 0.0 5.1 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 PRP89213.1 - 3.3e-05 24.2 6.1 0.82 10.4 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP89213.1 - 0.00053 19.5 5.5 0.013 14.9 3.1 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 PRP89213.1 - 0.011 16.3 7.0 11 6.6 0.4 4.2 3 1 1 5 5 3 0 Tetratricopeptide repeat zf-Mss51 PF13824.6 PRP89213.1 - 0.016 15.3 4.3 0.26 11.4 4.3 2.5 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SHNi-TPR PF10516.9 PRP89213.1 - 0.03 13.8 3.2 4.2 6.9 0.0 4.0 5 0 0 5 5 5 0 SHNi-TPR DUF410 PF04190.13 PRP89213.1 - 0.048 13.5 1.4 2.6 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF410) RPN7 PF10602.9 PRP89213.1 - 0.074 12.7 2.0 4.3 7.0 0.1 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_17 PF13431.6 PRP89213.1 - 0.076 13.4 2.5 3.8 8.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat C5HCH PF17982.1 PRP89213.1 - 0.13 12.5 1.9 0.28 11.4 1.9 1.5 1 0 0 1 1 1 0 NSD Cys-His rich domain TPR_9 PF13371.6 PRP89213.1 - 0.34 11.1 2.0 5.8 7.2 0.1 3.4 3 2 0 3 3 3 0 Tetratricopeptide repeat HemX PF04375.14 PRP89213.1 - 0.56 9.4 4.4 0.84 8.9 0.6 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase TIP41 PF04176.13 PRP89214.1 - 1.2e-57 194.1 0.0 1.6e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family PD40 PF07676.12 PRP89215.1 - 0.00011 22.0 10.9 0.39 10.7 0.1 5.1 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat F-box-like PF12937.7 PRP89215.1 - 0.0014 18.5 2.7 0.0096 15.8 2.7 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 PRP89215.1 - 0.0087 15.9 0.9 0.044 13.7 0.1 2.4 2 0 0 2 2 2 1 F-box domain LytB_WW PF18342.1 PRP89215.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Endo-beta-N-acetylglucosaminidase LytB WW domain Cu2_monoox_C PF03712.15 PRP89215.1 - 0.096 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DPPIV_N PF00930.21 PRP89215.1 - 0.12 11.1 0.5 5 5.8 0.0 3.1 4 0 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lon_C PF05362.13 PRP89216.1 - 2.2e-61 207.0 0.0 2.6e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 PRP89216.1 - 7.9e-07 29.0 0.0 1.5e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase Birna_VP4 PF01768.16 PRP89216.1 - 0.033 14.0 0.0 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 Birnavirus VP4 protein GDP_Man_Dehyd PF16363.5 PRP89217.1 - 1.6e-48 165.9 0.0 1.8e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PRP89217.1 - 1.9e-08 34.1 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Tricorn_PDZ PF14685.6 PRP89217.1 - 0.049 13.6 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain GXGXG PF01493.19 PRP89217.1 - 0.049 13.2 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 GXGXG motif ZinT PF09223.11 PRP89218.1 - 0.089 12.7 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment Colipase-like PF15083.6 PRP89221.1 - 0.016 15.3 8.1 0.044 13.9 8.1 1.7 1 0 0 1 1 1 0 Colipase-like Oxysterol_BP PF01237.18 PRP89224.1 - 1.8e-105 352.8 0.1 3e-105 352.1 0.1 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PA14 PF07691.12 PRP89224.1 - 0.002 17.9 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain PH PF00169.29 PRP89224.1 - 0.0073 16.8 1.6 0.0095 16.4 0.2 2.0 2 0 0 2 2 2 1 PH domain Peptidase_C1 PF00112.23 PRP89226.1 - 6.9e-60 202.8 2.4 6.9e-60 202.8 2.4 1.7 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PRP89226.1 - 1.4e-14 54.3 3.5 2.4e-14 53.5 3.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PRP89226.1 - 0.00032 19.6 2.6 0.0038 16.0 0.0 2.4 3 0 0 3 3 3 2 Peptidase C1-like family Chi-conotoxin PF16981.5 PRP89227.1 - 0.35 11.1 2.6 1.3 9.3 0.1 2.9 3 0 0 3 3 3 0 chi-Conotoxin or t superfamily HATPase_c PF02518.26 PRP89228.1 - 4.5e-29 101.2 0.2 9.5e-29 100.2 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP89228.1 - 2e-18 66.6 4.7 1.5e-16 60.6 1.0 3.5 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 PRP89228.1 - 9.6e-06 25.5 0.0 6.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP89228.1 - 0.0093 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 PRP89228.1 - 0.012 15.5 0.0 0.051 13.5 0.0 2.0 1 0 0 1 1 1 0 GHKL domain Nodulin_late PF07127.11 PRP89229.1 - 0.00038 20.7 1.7 0.00038 20.7 1.7 2.3 1 1 1 2 2 2 1 Late nodulin protein Carb_bind PF10645.9 PRP89229.1 - 0.01 16.0 12.1 0.01 16.0 12.1 2.7 1 1 1 2 2 2 0 Carbohydrate binding FOLN PF09289.10 PRP89229.1 - 0.057 13.6 4.9 1.2 9.3 3.5 2.7 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain ALO PF04030.14 PRP89230.1 - 1.8e-09 37.8 1.9 1e-08 35.4 1.9 2.0 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 PRP89230.1 - 2e-09 37.3 0.0 3.6e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Chol_subst-bind PF09129.11 PRP89230.1 - 0.021 13.8 2.2 0.098 11.6 0.9 2.4 3 0 0 3 3 3 0 Cholesterol oxidase, substrate-binding FAD_binding_5 PF00941.21 PRP89230.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase Colipase-like PF15083.6 PRP89231.1 - 0.005 16.9 9.0 0.0089 16.1 9.0 1.4 1 0 0 1 1 1 1 Colipase-like RAP1 PF07218.11 PRP89231.1 - 1.2 7.4 16.3 1.5 7.0 16.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nodulin_late PF07127.11 PRP89231.1 - 6.7 7.1 7.3 1.3 9.4 0.5 2.3 2 0 0 2 2 2 0 Late nodulin protein EF-hand_5 PF13202.6 PRP89232.1 - 4.9e-05 22.6 13.2 2.4 7.8 0.3 4.4 4 0 0 4 4 4 4 EF hand Dockerin_1 PF00404.18 PRP89232.1 - 0.013 15.7 14.0 1.5 9.1 2.2 4.3 1 1 3 4 4 4 0 Dockerin type I domain Med25_VWA PF11265.8 PRP89232.1 - 0.02 14.7 1.2 4.8 7.0 0.1 2.3 2 0 0 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A PPR_3 PF13812.6 PRP89232.1 - 0.03 14.4 1.1 9.8 6.3 0.1 2.9 2 0 0 2 2 2 0 Pentatricopeptide repeat domain EF-hand_6 PF13405.6 PRP89232.1 - 0.18 11.8 9.8 51 4.2 0.1 4.5 4 0 0 4 4 4 0 EF-hand domain DUF4706 PF15797.5 PRP89232.1 - 5.4 7.6 6.5 2.4 8.8 2.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4706) HATPase_c PF02518.26 PRP89233.1 - 1.1e-25 90.3 0.0 3.8e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP89233.1 - 3.1e-24 85.3 1.1 3.3e-22 78.8 1.2 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 PRP89233.1 - 4.4e-10 39.4 0.1 9.6e-09 35.2 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Occludin_ELL PF07303.13 PRP89234.1 - 0.11 13.2 0.2 0.11 13.2 0.2 10.3 6 4 5 12 12 12 0 Occludin homology domain LAMTOR PF15454.6 PRP89237.1 - 0.00055 20.5 0.0 0.00055 20.5 0.0 3.1 4 0 0 4 4 4 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Megourin PF17560.2 PRP89237.1 - 0.053 13.8 0.8 0.053 13.8 0.8 1.9 2 0 0 2 2 2 0 Aphid Megourins RhoGAP PF00620.27 PRP89238.1 - 1.1e-48 164.9 0.2 7.5e-48 162.2 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain SH3_9 PF14604.6 PRP89238.1 - 3.2e-12 46.1 0.0 7.1e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 PRP89238.1 - 3.8e-11 42.4 0.1 6.7e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 PRP89238.1 - 2.8e-09 36.5 0.1 5.1e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GABP-alpha PF11620.8 PRP89238.1 - 0.01 16.0 0.1 0.046 13.9 0.1 2.1 1 0 0 1 1 1 0 GA-binding protein alpha chain GrpE PF01025.19 PRP89238.1 - 0.045 13.4 9.5 0.1 12.3 9.5 1.6 1 0 0 1 1 1 0 GrpE PH PF00169.29 PRP89238.1 - 0.067 13.7 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 PH domain RA PF00788.23 PRP89238.1 - 0.093 13.4 0.1 4.9 7.8 0.0 2.7 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain YukD PF08817.10 PRP89238.1 - 0.1 13.3 0.0 0.65 10.7 0.0 2.3 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD BRE1 PF08647.11 PRP89238.1 - 0.24 11.5 10.9 0.71 10.0 10.9 1.8 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase LMBR1 PF04791.16 PRP89238.1 - 0.83 8.5 4.1 1.3 7.9 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 PRP89238.1 - 3.7 7.6 7.3 4.5 7.3 3.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) 4HBT PF03061.22 PRP89239.1 - 1.4e-08 34.9 0.0 5.9e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 PRP89239.1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Homeodomain PF00046.29 PRP89240.1 - 1.2e-15 57.1 3.4 1.9e-15 56.4 1.7 2.1 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 PRP89240.1 - 9.9e-05 22.2 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF1857 PF08982.11 PRP89243.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1857) DUF905 PF06006.12 PRP89243.1 - 0.13 12.3 0.2 0.24 11.4 0.2 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF905) CLU PF13236.6 PRP89245.1 - 3.1e-81 272.4 0.1 5.9e-81 271.5 0.1 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP89245.1 - 2.6e-40 138.3 0.9 6e-40 137.1 0.1 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 PRP89245.1 - 5.6e-23 81.0 12.0 2e-11 44.0 0.4 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 PRP89245.1 - 6.2e-15 54.5 8.6 0.0017 18.2 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 PRP89245.1 - 6.3e-13 48.9 1.2 2.8e-12 46.8 0.5 2.6 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 PRP89245.1 - 0.0023 18.0 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) SPG48 PF14764.6 PRP89245.1 - 0.13 12.7 0.4 0.57 10.7 0.0 2.2 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking DUF4449 PF14613.6 PRP89245.1 - 0.72 9.9 10.3 0.13 12.4 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) TPR_8 PF13181.6 PRP89245.1 - 0.86 10.0 6.6 4.1 7.9 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LAT PF15234.6 PRP89246.1 - 3.6 7.2 11.1 5 6.8 1.5 2.2 1 1 1 2 2 2 0 Linker for activation of T-cells Rhomboid PF01694.22 PRP89247.1 - 1.3e-08 35.0 2.4 1.3e-08 35.0 2.4 1.5 2 0 0 2 2 2 1 Rhomboid family LRR_8 PF13855.6 PRP89248.1 - 7e-16 57.7 30.4 0.00014 21.6 4.1 5.1 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PRP89248.1 - 8.2e-15 54.7 31.9 6.2e-05 23.3 0.2 5.7 4 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PRP89248.1 - 7e-13 48.4 13.8 9.4e-07 28.5 0.9 4.0 1 1 2 3 3 3 3 Leucine-rich repeat HA PF03457.14 PRP89249.1 - 1.4e-13 50.9 3.7 0.00015 22.0 0.0 3.7 3 0 0 3 3 3 3 Helicase associated domain zf-MYND PF01753.18 PRP89250.1 - 5.6e-11 42.3 10.5 8.7e-11 41.7 10.5 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 PRP89250.1 - 0.049 13.9 7.9 0.089 13.1 7.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 PRP89250.1 - 0.086 13.0 4.9 0.16 12.1 4.9 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_tranf_2_4 PF13704.6 PRP89250.1 - 0.14 12.6 0.1 0.33 11.5 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 DHC_N2 PF08393.13 PRP89251.1 - 5.2e-78 262.9 1.2 5.2e-78 262.9 1.2 3.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 PRP89251.1 - 2.5e-57 194.3 5.8 8e-46 156.5 0.0 4.4 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region AAA_9 PF12781.7 PRP89251.1 - 1.4e-46 158.4 7.5 2.7e-46 157.4 0.7 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 PRP89251.1 - 1.2e-43 149.6 1.7 1.9e-42 145.6 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 PRP89251.1 - 4.6e-33 114.2 0.1 2.7e-31 108.5 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region Dynein_heavy PF03028.15 PRP89251.1 - 8.7e-28 96.8 1.2 6.3e-27 94.0 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 PRP89251.1 - 2.2e-25 89.4 0.0 6.2e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 PRP89251.1 - 7.6e-16 58.4 3.8 1e-15 57.9 0.9 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_8 PF12780.7 PRP89251.1 - 1.3e-15 57.5 0.3 1.3e-15 57.5 0.3 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 MT PF12777.7 PRP89251.1 - 4.2e-14 52.3 5.6 4.2e-14 52.3 5.6 2.9 2 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor zf-RING_2 PF13639.6 PRP89251.1 - 9.5e-13 48.3 5.9 2.6e-12 46.8 5.9 1.9 1 0 0 1 1 1 1 Ring finger domain AAA_lid_1 PF17857.1 PRP89251.1 - 5.8e-11 42.5 0.0 2.5e-10 40.5 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain zf-RING_11 PF17123.5 PRP89251.1 - 1.2e-08 34.6 4.0 2.8e-08 33.3 4.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PRP89251.1 - 3.3e-08 33.2 5.8 8e-08 32.0 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AAA_5 PF07728.14 PRP89251.1 - 6.2e-08 32.7 0.0 0.00015 21.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) zf-rbx1 PF12678.7 PRP89251.1 - 7.6e-08 32.5 4.7 2.1e-07 31.1 4.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PRP89251.1 - 4e-06 26.6 5.7 1e-05 25.3 5.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PRP89251.1 - 9.9e-06 25.3 3.7 2.6e-05 24.0 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP89251.1 - 4.1e-05 23.5 6.5 8.5e-05 22.4 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain AAA PF00004.29 PRP89251.1 - 0.00022 21.6 0.1 0.23 11.9 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) zf-ANAPC11 PF12861.7 PRP89251.1 - 0.00024 21.1 0.8 0.00068 19.6 0.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger ABC_tran PF00005.27 PRP89251.1 - 0.00036 21.1 1.9 3.5 8.1 0.2 4.5 4 0 0 4 4 3 1 ABC transporter Rad17 PF03215.15 PRP89251.1 - 0.0023 17.9 0.1 7.4 6.4 0.0 4.0 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_16 PF13191.6 PRP89251.1 - 0.0028 18.0 0.1 0.15 12.5 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain zf-RING_UBOX PF13445.6 PRP89251.1 - 0.0042 17.1 2.5 0.012 15.7 2.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PRP89251.1 - 0.017 14.9 4.4 0.046 13.6 4.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AAA_28 PF13521.6 PRP89251.1 - 0.034 14.4 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 PRP89251.1 - 0.039 14.3 0.0 0.26 11.7 0.0 2.5 2 0 0 2 2 1 0 RNA helicase TsaE PF02367.17 PRP89251.1 - 0.11 12.5 0.2 1.9 8.5 0.2 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 PRP89251.1 - 0.25 11.7 6.0 2.5 8.4 0.2 4.8 5 0 0 5 5 5 0 AAA domain AAA_29 PF13555.6 PRP89251.1 - 0.33 10.7 1.0 4.7 7.0 0.0 2.9 3 0 0 3 3 3 0 P-loop containing region of AAA domain zf-RING_4 PF14570.6 PRP89251.1 - 0.61 9.9 5.6 1.5 8.7 5.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 PRP89251.1 - 1.3 8.7 5.3 3.3 7.4 5.3 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PRP89251.1 - 1.4 9.1 7.3 7.2 6.9 7.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain COG2 PF06148.11 PRP89251.1 - 3.2 7.8 11.4 9.5 6.3 2.4 4.8 4 0 0 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 PHD PF00628.29 PRP89251.1 - 5.1 7.1 5.6 12 5.9 5.6 1.7 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 PRP89251.1 - 5.3 7.2 6.6 17 5.6 6.6 2.0 1 0 0 1 1 1 0 RING-variant domain MRPL52 PF18699.1 PRP89251.1 - 9.8 6.4 7.5 20 5.4 1.6 3.5 2 0 0 2 2 2 0 Mitoribosomal protein mL52 DUF716 PF04819.12 PRP89252.1 - 0.12 12.0 6.4 0.053 13.2 2.3 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF716) Glyco_hydro_cc PF11790.8 PRP89253.1 - 4.2e-59 200.0 6.8 5.7e-57 193.0 1.9 2.6 3 0 0 3 3 3 2 Glycosyl hydrolase catalytic core X8 PF07983.13 PRP89253.1 - 1.2e-09 38.8 4.7 3e-09 37.4 4.7 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.18 PRP89253.1 - 4.9e-09 36.2 0.1 1.5e-08 34.6 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DEAD PF00270.29 PRP89254.1 - 2e-11 44.0 0.0 5.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PRP89254.1 - 5.1e-07 29.9 0.0 1.9e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PRP89254.1 - 0.019 15.3 0.0 0.17 12.2 0.0 2.8 2 0 0 2 2 2 0 Helicase conserved C-terminal domain ATP-synt_DE PF00401.20 PRP89255.1 - 0.048 13.9 0.1 0.095 13.0 0.1 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Acetyltransf_13 PF13880.6 PRP89256.1 - 9.9e-17 60.7 0.0 2.1e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 PRP89256.1 - 5.2e-16 58.2 0.1 1.1e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 PRP89256.1 - 0.00026 21.2 0.0 0.00054 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PRP89256.1 - 0.00076 19.9 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YoeB_toxin PF06769.14 PRP89256.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 1 0 1 1 1 0 YoeB-like toxin of bacterial type II toxin-antitoxin system DUF1772 PF08592.11 PRP89257.1 - 1.5e-16 61.0 1.9 1.5e-16 61.0 1.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Myb_DNA-binding PF00249.31 PRP89257.1 - 1.4e-10 41.2 0.0 3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 PRP89257.1 - 1e-05 25.2 4.4 2e-05 24.3 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 PRP89257.1 - 0.00012 22.2 0.7 0.0004 20.6 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain EST1_DNA_bind PF10373.9 PRP89257.1 - 0.052 13.0 0.2 0.09 12.2 0.2 1.3 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Drf_GBD PF06371.13 PRP89257.1 - 2.6 7.6 5.1 8.9 5.8 3.7 2.2 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain EF-hand_5 PF13202.6 PRP89258.1 - 0.00023 20.5 7.8 1.9 8.1 0.3 3.4 3 0 0 3 3 3 3 EF hand Dockerin_1 PF00404.18 PRP89258.1 - 0.0069 16.6 7.4 5.3 7.3 2.1 3.6 1 1 3 4 4 4 4 Dockerin type I domain EF-hand_6 PF13405.6 PRP89258.1 - 0.61 10.2 6.1 48 4.3 0.1 3.6 3 0 0 3 3 3 0 EF-hand domain Y_phosphatase PF00102.27 PRP89261.1 - 8.5e-65 218.6 0.0 1.7e-64 217.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Sec7 PF01369.20 PRP89261.1 - 1.2e-58 197.9 1.7 1.5e-58 197.5 0.2 2.0 2 0 0 2 2 2 1 Sec7 domain TatD_DNase PF01026.21 PRP89261.1 - 9e-33 113.7 0.0 2.2e-32 112.5 0.0 1.6 1 0 0 1 1 1 1 TatD related DNase RhoGEF PF00621.20 PRP89261.1 - 1.6e-22 80.6 5.5 1.6e-22 80.6 5.5 3.0 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 PRP89261.1 - 4.5e-21 75.3 1.5 8.4e-07 29.5 0.1 5.3 4 1 0 4 4 4 4 PH domain RGS PF00615.19 PRP89261.1 - 5.2e-06 26.7 0.3 4.5e-05 23.7 0.0 2.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 PRP89261.1 - 1.6e-05 24.9 0.0 0.00053 20.0 0.1 2.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DSPc PF00782.20 PRP89261.1 - 6.4e-05 22.8 0.1 0.00039 20.3 0.0 2.4 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PP2C_2 PF13672.6 PRP89261.1 - 0.00046 19.9 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C Y_phosphatase3 PF13350.6 PRP89261.1 - 0.011 15.7 0.6 0.042 13.8 0.1 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family IQ PF00612.27 PRP89261.1 - 0.013 15.2 0.2 0.085 12.7 0.2 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF2012 PF09430.10 PRP89262.1 - 1.7e-24 86.3 0.0 3.8e-24 85.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 PRP89262.1 - 0.0016 18.6 0.0 0.003 17.8 0.0 1.5 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 PRP89262.1 - 0.04 13.7 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II RasGEF PF00617.19 PRP89263.1 - 3.9e-35 121.6 0.3 1e-34 120.3 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain V4R PF02830.18 PRP89263.1 - 4.8e-10 39.3 0.1 4.8e-10 39.3 0.1 2.6 2 0 0 2 2 2 1 V4R domain RasGEF_N PF00618.20 PRP89263.1 - 0.0016 18.7 0.5 0.0086 16.3 0.1 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif BTB_2 PF02214.22 PRP89265.1 - 1.4e-05 25.3 0.0 2.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TetR_C_8 PF14278.6 PRP89265.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region DEAD_2 PF06733.15 PRP89266.1 - 4.7e-50 169.6 0.1 1.2e-49 168.3 0.0 1.7 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 PRP89266.1 - 2.9e-43 148.0 0.0 7.7e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 PRP89266.1 - 6.5e-36 123.8 0.0 2.6e-28 99.0 0.0 2.3 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 PRP89266.1 - 2.5e-06 27.6 0.1 4.8e-05 23.4 0.1 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 PRP89266.1 - 0.021 13.6 0.0 0.082 11.6 0.0 1.8 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_16 PF13191.6 PRP89266.1 - 0.074 13.4 0.0 8.8 6.7 0.0 3.1 2 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 PRP89266.1 - 0.11 13.0 0.2 6.5 7.2 0.1 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DPBB_1 PF03330.18 PRP89267.1 - 1.2e-10 41.6 0.0 3.5e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Lytic transglycolase Chitin_bind_1 PF00187.19 PRP89267.1 - 1e-07 32.3 22.2 1e-07 32.3 22.2 2.5 2 0 0 2 2 2 1 Chitin recognition protein Rieske PF00355.26 PRP89267.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DPBB_1 PF03330.18 PRP89268.1 - 3.5e-11 43.2 0.0 7.4e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Lytic transglycolase Chitin_bind_1 PF00187.19 PRP89268.1 - 2.4e-09 37.5 22.3 2.4e-09 37.5 22.3 2.5 4 0 0 4 4 4 1 Chitin recognition protein LRR_8 PF13855.6 PRP89269.1 - 5.5e-08 32.5 13.5 0.16 11.7 0.0 5.8 5 1 1 6 6 6 4 Leucine rich repeat PA PF02225.22 PRP89269.1 - 1.6e-07 31.3 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 PA domain LRR_4 PF12799.7 PRP89269.1 - 0.0001 22.6 11.9 3.1 8.4 0.0 6.9 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP89269.1 - 0.16 12.1 2.6 38 4.7 0.0 5.4 7 0 0 7 7 7 0 Leucine Rich repeat SCIMP PF15050.6 PRP89269.1 - 0.36 11.3 2.0 0.44 11.0 0.1 2.0 2 0 0 2 2 2 0 SCIMP protein Arteri_Gl PF00951.18 PRP89269.1 - 3.7 7.3 10.9 0.14 11.9 3.7 2.4 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Pkinase PF00069.25 PRP89271.1 - 3.9e-67 226.4 0.0 5.7e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89271.1 - 9.3e-40 136.5 0.0 1.2e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP89271.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PRP89271.1 - 2.8e-06 27.1 0.2 4.5e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 PRP89271.1 - 3e-06 26.8 0.0 5.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PRP89271.1 - 4.4e-05 22.6 0.5 7e-05 21.9 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP89271.1 - 0.00038 20.4 0.0 0.0067 16.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 PRP89271.1 - 0.0062 16.2 0.4 0.01 15.4 0.1 1.4 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 PRP89271.1 - 0.028 13.2 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 PRP89271.1 - 0.036 13.6 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH_6_hur PF04655.14 PRP89271.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.6 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase FTA2 PF13095.6 PRP89271.1 - 0.065 12.8 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 PRP89271.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Peptidase_M3 PF01432.20 PRP89272.1 - 7.4e-104 348.5 0.0 3.2e-103 346.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M3 HLH PF00010.26 PRP89273.1 - 3.4e-06 26.9 1.1 6.6e-06 26.0 1.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Shugoshin_N PF07558.11 PRP89273.1 - 0.00042 20.1 1.4 0.0033 17.3 1.2 2.4 1 1 1 2 2 2 1 Shugoshin N-terminal coiled-coil region Cep57_CLD_2 PF14197.6 PRP89273.1 - 0.011 15.8 0.2 0.16 12.0 0.2 2.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 MIF4G_like_2 PF09090.11 PRP89273.1 - 0.027 14.0 0.8 0.031 13.8 0.5 1.3 1 1 0 1 1 1 0 MIF4G like THOC7 PF05615.13 PRP89273.1 - 0.034 14.4 6.2 0.064 13.5 6.1 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 DUF725 PF05267.12 PRP89273.1 - 0.035 14.1 0.4 0.035 14.1 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF725) YabA PF06156.13 PRP89273.1 - 0.038 14.6 2.6 0.038 14.6 2.6 1.9 1 1 1 2 2 2 0 Initiation control protein YabA DASH_Dam1 PF08653.10 PRP89273.1 - 0.041 13.7 0.2 0.091 12.6 0.1 1.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 DivIC PF04977.15 PRP89273.1 - 0.052 13.3 0.7 0.052 13.3 0.7 2.8 2 1 1 3 3 3 0 Septum formation initiator KASH PF10541.9 PRP89273.1 - 0.064 13.5 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain AnfO_nitrog PF09582.10 PRP89273.1 - 0.073 12.4 1.5 0.1 11.9 1.5 1.3 1 1 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) BLOC1_2 PF10046.9 PRP89273.1 - 0.083 13.2 2.4 0.6 10.5 0.1 2.3 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 PRP89273.1 - 0.12 12.4 0.9 0.19 11.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 PRP89273.1 - 0.13 12.8 1.7 0.91 10.0 0.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 PRP89273.1 - 0.21 11.7 8.9 0.34 11.0 8.9 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 PRP89273.1 - 0.28 10.9 3.2 0.36 10.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) FapA PF03961.13 PRP89273.1 - 0.33 9.5 3.6 0.53 8.8 3.7 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A NYD-SP28_assoc PF14775.6 PRP89273.1 - 0.35 11.0 3.4 1.4 9.1 0.2 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain Spc24 PF08286.11 PRP89273.1 - 1.1 9.5 6.2 0.32 11.3 2.7 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.25 PRP89274.1 - 1.2e-46 159.3 0.0 1.4e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89274.1 - 5.3e-26 91.5 0.0 6.4e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP89274.1 - 2.4e-07 30.9 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP89274.1 - 1e-06 27.8 0.1 1.8e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP89274.1 - 2.2e-05 23.9 0.0 3.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PRP89274.1 - 0.0023 17.0 0.2 0.0073 15.3 0.2 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PRP89274.1 - 0.0026 17.1 0.0 0.46 9.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Choline_kinase PF01633.20 PRP89274.1 - 0.11 12.1 0.3 1 8.9 0.4 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF3945 PF13101.6 PRP89274.1 - 0.16 11.8 0.0 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) FTA2 PF13095.6 PRP89274.1 - 0.17 11.5 0.1 0.28 10.8 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GST_C_3 PF14497.6 PRP89276.1 - 2e-21 76.0 0.0 2.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PRP89276.1 - 1.4e-09 38.1 0.0 2.3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PRP89276.1 - 5e-08 33.2 0.0 1.2e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PRP89276.1 - 4.6e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PRP89276.1 - 0.00029 21.2 0.0 0.0008 19.8 0.0 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PRP89276.1 - 0.032 14.5 0.0 0.071 13.4 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PRP89276.1 - 0.19 12.5 0.0 0.4 11.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain MIT PF04212.18 PRP89277.1 - 3.3e-12 46.3 0.3 1.3e-11 44.4 0.1 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Importin_rep_6 PF18829.1 PRP89277.1 - 0.98 9.6 5.4 2.3 8.4 2.1 2.7 2 0 0 2 2 2 0 Importin repeat 6 Occludin_ELL PF07303.13 PRP89277.1 - 5 7.9 11.4 0.2 12.4 1.1 2.9 2 2 1 3 3 3 0 Occludin homology domain Ras PF00071.22 PRP89278.1 - 5.9e-46 156.0 0.1 7.2e-46 155.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89278.1 - 1.8e-14 54.0 0.0 2.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89278.1 - 5.6e-09 35.7 0.0 7.1e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP89278.1 - 2.8e-06 27.0 0.1 5.1e-06 26.2 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP89278.1 - 0.00053 19.9 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 PRP89278.1 - 0.0089 15.6 0.0 0.014 14.9 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 PRP89278.1 - 0.043 13.8 0.0 0.15 12.0 0.0 1.9 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain RhoGAP PF00620.27 PRP89279.1 - 2.2e-36 125.0 0.0 4.5e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.32 PRP89279.1 - 0.0015 19.3 0.3 0.0015 19.3 0.3 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Fer2_BFD PF04324.15 PRP89283.1 - 0.061 13.7 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain NuA4 PF09340.10 PRP89284.1 - 0.1 12.5 0.1 12 5.9 0.0 2.2 1 1 1 2 2 2 0 Histone acetyltransferase subunit NuA4 Pkinase PF00069.25 PRP89285.1 - 7e-45 153.4 0.0 9.5e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pirin PF02678.16 PRP89285.1 - 5.8e-29 100.2 0.8 1.7e-28 98.7 0.1 2.1 2 0 0 2 2 2 1 Pirin Pkinase_Tyr PF07714.17 PRP89285.1 - 4.8e-19 68.7 0.0 1.5e-18 67.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pirin_C_2 PF17954.1 PRP89285.1 - 1.6e-16 60.2 0.0 4e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 PRP89285.1 - 2e-07 30.6 0.4 3.5e-06 26.6 0.1 2.4 2 0 0 2 2 2 1 Cupin domain Kdo PF06293.14 PRP89285.1 - 1.8e-05 24.2 0.0 4.8e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP89285.1 - 6.7e-05 22.9 0.0 0.00016 21.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PRP89285.1 - 0.0035 16.7 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PRP89285.1 - 0.0048 15.7 0.0 0.0094 14.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP89285.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Cupin_8 PF13621.6 PRP89286.1 - 1.1e-76 257.9 0.0 1.3e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain PPR_3 PF13812.6 PRP89287.1 - 1.7 8.8 4.0 4.4 7.5 0.2 3.0 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Syja_N PF02383.18 PRP89289.1 - 5.3e-70 236.3 0.6 2.6e-69 234.0 0.6 2.1 1 1 0 1 1 1 1 SacI homology domain DUF5638 PF18688.1 PRP89289.1 - 2.5 8.4 5.8 4.4 7.7 0.1 3.8 6 0 0 6 6 6 0 Family of unknown function (DUF5638) zf-C3HC4_3 PF13920.6 PRP89291.1 - 1.4e-08 34.4 5.5 1.6e-08 34.3 5.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PRP89291.1 - 0.0019 18.5 6.0 0.0026 18.1 6.0 1.2 1 0 0 1 1 1 1 Ring finger domain Ribosomal_S27e PF01667.17 PRP89291.1 - 0.0074 16.0 7.7 0.032 13.9 7.7 1.9 1 1 0 1 1 1 1 Ribosomal protein S27 zinc-ribbons_6 PF07191.12 PRP89291.1 - 0.015 15.3 7.1 0.019 15.0 7.1 1.1 1 0 0 1 1 1 0 zinc-ribbons Prok-RING_4 PF14447.6 PRP89291.1 - 0.031 14.1 4.1 0.049 13.5 4.1 1.4 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PRP89291.1 - 0.032 14.2 9.6 0.097 12.6 9.6 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Rhodanese_C PF12368.8 PRP89291.1 - 0.16 12.3 9.1 3.4 8.1 9.4 2.1 1 1 1 2 2 2 0 Rhodanase C-terminal zf-AN1 PF01428.16 PRP89291.1 - 0.22 11.7 7.5 0.37 11.0 2.7 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger zf-MYND PF01753.18 PRP89291.1 - 2.9 8.1 11.0 2.7 8.2 3.8 2.4 1 1 1 2 2 2 0 MYND finger C1_1 PF00130.22 PRP89291.1 - 6.2 6.8 11.6 1.1e+02 2.8 11.5 2.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-TFIIIC PF12660.7 PRP89292.1 - 6.9e-11 42.0 0.4 1.8e-10 40.7 0.4 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 PRP89292.1 - 8.2e-10 38.9 0.0 2.1e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term WD40 PF00400.32 PRP89292.1 - 8.7e-06 26.4 5.1 0.0012 19.7 0.2 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat PhnA_Zn_Ribbon PF08274.12 PRP89292.1 - 0.00043 20.2 2.9 0.0084 16.0 0.8 2.9 2 1 0 2 2 2 1 PhnA Zinc-Ribbon ANAPC4_WD40 PF12894.7 PRP89292.1 - 0.022 15.0 0.0 0.1 12.9 0.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain zf-ribbon_3 PF13248.6 PRP89292.1 - 0.025 14.0 2.6 1.7 8.2 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 PRP89292.1 - 0.17 12.0 1.6 7.4 6.7 0.1 2.6 2 0 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 PRP89292.1 - 0.34 10.8 5.3 5.4 7.0 1.0 2.8 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_Tnp_IS1595 PF12760.7 PRP89292.1 - 1.6 8.7 5.4 3.4 7.7 0.0 2.9 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DNA_ligase_ZBD PF03119.16 PRP89292.1 - 7.3 6.7 8.4 3.6 7.7 0.5 3.0 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Nudix_N_2 PF14803.6 PRP89292.1 - 7.4 6.6 6.1 6.8 6.7 0.3 3.0 2 1 1 3 3 3 0 Nudix N-terminal Homeodomain PF00046.29 PRP89293.1 - 1.6e-13 50.2 4.8 2.2e-13 49.8 4.8 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PRP89293.1 - 1.7e-05 24.6 0.9 3.1e-05 23.8 0.9 1.4 1 0 0 1 1 1 1 Homeobox KN domain MFS_1 PF07690.16 PRP89295.1 - 1.1e-11 44.3 24.8 1.1e-11 44.3 24.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily VIT1 PF01988.19 PRP89295.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.6 2 1 1 3 3 3 0 VIT family Pkinase PF00069.25 PRP89296.1 - 2.1e-48 165.0 0.0 2.5e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89296.1 - 6.2e-26 91.2 0.0 7.1e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP89296.1 - 1.4e-09 37.7 0.0 1.4e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 PRP89296.1 - 1e-06 28.0 0.0 3.6e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PRP89296.1 - 2.4e-05 24.4 0.0 3.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP89296.1 - 9.6e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP89296.1 - 0.0017 17.2 0.0 0.0041 16.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 PRP89296.1 - 0.042 13.4 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 PRP89296.1 - 0.045 12.8 0.0 0.075 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CLU PF13236.6 PRP89297.1 - 6.9e-45 153.6 0.0 1.5e-44 152.5 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria ADH_zinc_N_2 PF13602.6 PRP89298.1 - 9e-20 72.1 0.1 1.2e-19 71.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PRP89298.1 - 2.8e-16 59.7 0.0 4.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RNA_pol_Rpb1_5 PF04998.17 PRP89299.1 - 6.9e-86 288.0 6.6 2e-84 283.2 6.6 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PRP89299.1 - 1.8e-62 210.4 0.1 4.7e-62 209.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PRP89299.1 - 4.2e-36 124.2 0.0 1.2e-33 116.3 0.0 3.7 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 PRP89299.1 - 9.9e-21 74.4 2.7 1e-18 67.7 1.4 3.6 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 PRP89299.1 - 3.8e-18 65.4 0.0 2.1e-17 63.0 0.0 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 NuDC PF16273.5 PRP89299.1 - 0.0011 19.5 1.3 0.0011 19.5 1.3 3.9 3 1 0 3 3 3 1 Nuclear distribution C domain Rad54_N PF08658.10 PRP89299.1 - 0.29 11.3 11.9 0.012 15.7 4.5 2.3 2 0 0 2 2 2 0 Rad54 N terminal EST1_DNA_bind PF10373.9 PRP89300.1 - 1.7e-41 142.6 5.5 3.3e-41 141.6 5.5 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 PRP89300.1 - 1.3e-16 61.5 4.3 1.1e-15 58.5 4.3 2.7 1 1 0 1 1 1 1 Telomerase activating protein Est1 Metallophos PF00149.28 PRP89300.1 - 1.3e-09 38.8 0.1 4e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase OmpH PF03938.14 PRP89300.1 - 0.21 12.0 1.0 0.47 10.8 1.0 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 PRP89300.1 - 1.5 9.1 4.7 5.1 7.5 0.4 3.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DiS_P_DiS PF06750.13 PRP89301.1 - 0.0019 18.3 0.1 0.034 14.3 0.0 2.1 2 0 0 2 2 2 1 Bacterial Peptidase A24 N-terminal domain LRR_8 PF13855.6 PRP89302.1 - 7.8e-67 220.9 135.8 5.6e-10 38.8 6.9 8.9 3 1 11 14 14 14 13 Leucine rich repeat LRR_4 PF12799.7 PRP89302.1 - 2.9e-52 173.7 74.8 1.3e-08 35.0 0.6 10.8 7 3 3 11 11 11 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP89302.1 - 5.1e-10 38.5 58.4 0.71 10.7 0.0 16.5 15 2 0 15 15 15 5 Leucine Rich Repeat LRR_9 PF14580.6 PRP89302.1 - 2.3e-09 37.0 28.4 0.0039 16.7 2.7 4.8 3 1 1 4 4 4 4 Leucine-rich repeat CSTF_C PF14304.6 PRP89302.1 - 5.2 6.7 7.5 50 3.6 0.0 5.1 7 0 0 7 7 7 0 Transcription termination and cleavage factor C-terminal DUF3886 PF13025.6 PRP89303.1 - 0.0025 18.0 5.3 0.0025 18.0 5.3 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3886) Presenilin PF01080.17 PRP89303.1 - 7.2 5.3 10.3 9.5 4.9 10.3 1.2 1 0 0 1 1 1 0 Presenilin Cyclin_N PF00134.23 PRP89304.1 - 5.9e-09 35.7 0.0 9.9e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 PRP89304.1 - 1.1e-07 32.3 0.0 1.7e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cofilin_ADF PF00241.20 PRP89306.1 - 5.8e-26 90.7 1.7 6.6e-26 90.5 1.7 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UPF0047 PF01894.17 PRP89306.1 - 0.082 13.1 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 Homeodomain PF00046.29 PRP89307.1 - 7.7e-18 64.1 1.2 2e-17 62.7 1.2 1.8 1 0 0 1 1 1 1 Homeodomain Methyltransf_32 PF13679.6 PRP89307.1 - 6.2e-06 26.3 0.3 6.2e-06 26.3 0.3 2.8 2 1 0 2 2 2 1 Methyltransferase domain Homeobox_KN PF05920.11 PRP89307.1 - 0.0011 18.9 0.8 0.0028 17.5 0.8 1.7 1 0 0 1 1 1 1 Homeobox KN domain GidB PF02527.15 PRP89307.1 - 0.0021 17.4 0.0 0.0087 15.4 0.0 2.1 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Glyco_hydro_31 PF01055.26 PRP89308.1 - 4.4e-145 484.2 9.3 8.9e-145 483.2 9.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 PRP89308.1 - 1.2e-26 93.2 0.4 1.2e-26 93.2 0.4 2.1 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase PAN_4 PF14295.6 PRP89308.1 - 7.5e-21 73.8 24.0 3.3e-08 33.3 4.6 3.8 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 PRP89308.1 - 8.5e-19 67.3 10.4 1.4e-06 28.2 0.1 3.7 3 0 0 3 3 3 3 PAN domain Homeodomain PF00046.29 PRP89308.1 - 3.8e-13 49.1 7.9 9e-13 47.9 7.9 1.6 1 0 0 1 1 1 1 Homeodomain PAN_2 PF08276.11 PRP89308.1 - 5.4e-09 36.1 18.4 0.0084 16.2 0.3 4.0 3 0 0 3 3 3 3 PAN-like domain Gal_mutarotas_2 PF13802.6 PRP89308.1 - 2.9e-08 33.9 3.6 3.6e-08 33.6 0.4 2.8 3 0 0 3 3 3 1 Galactose mutarotase-like Homeobox_KN PF05920.11 PRP89308.1 - 5.9e-05 22.9 4.6 0.00013 21.8 4.6 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF5110 PF17137.4 PRP89308.1 - 0.12 12.7 0.0 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) BrkDBD PF09607.10 PRP89308.1 - 0.42 10.4 1.9 1.3 8.9 1.9 1.8 1 0 0 1 1 1 0 Brinker DNA-binding domain PAN_3 PF08277.12 PRP89308.1 - 1.1 9.1 18.0 1.6 8.6 1.2 3.5 3 0 0 3 3 3 0 PAN-like domain X8 PF07983.13 PRP89312.1 - 1.5e-09 38.4 2.1 4.1e-09 37.0 2.1 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.18 PRP89312.1 - 2.1e-09 37.4 0.7 2.1e-09 37.4 0.7 2.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 17 RIFIN PF02009.16 PRP89312.1 - 0.032 14.1 3.8 0.028 14.3 2.4 1.6 2 0 0 2 2 2 0 Rifin Podoplanin PF05808.11 PRP89312.1 - 0.3 11.2 14.1 0.28 11.3 12.0 1.9 2 0 0 2 2 2 0 Podoplanin Miga PF10265.9 PRP89312.1 - 8.9 5.1 8.8 13 4.6 8.8 1.1 1 0 0 1 1 1 0 Mitoguardin MMM1 PF10296.9 PRP89313.1 - 0.019 14.1 0.1 0.023 13.8 0.1 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 RhoGAP PF00620.27 PRP89314.1 - 4.6e-41 140.2 0.0 4.6e-41 140.2 0.0 4.1 5 0 0 5 5 5 1 RhoGAP domain LIM PF00412.22 PRP89314.1 - 1.5e-27 95.6 17.1 1.9e-15 56.8 4.5 2.6 2 0 0 2 2 2 2 LIM domain RhoGEF PF00621.20 PRP89314.1 - 2.3e-22 80.1 6.1 2.3e-22 80.1 6.1 3.7 3 1 0 4 4 4 1 RhoGEF domain DUF4335 PF14233.6 PRP89314.1 - 0.019 14.9 0.4 0.068 13.1 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) C1_4 PF07975.12 PRP89314.1 - 0.02 15.1 10.2 0.53 10.6 1.9 2.9 2 0 0 2 2 2 0 TFIIH C1-like domain TilS PF09179.11 PRP89314.1 - 0.025 15.1 2.6 1.2 9.6 0.1 2.9 2 1 0 2 2 2 0 TilS substrate binding domain PH PF00169.29 PRP89314.1 - 0.033 14.7 1.3 0.12 12.9 0.0 2.7 2 0 0 2 2 2 0 PH domain MttA_Hcf106 PF02416.16 PRP89314.1 - 2 7.8 0.0 2 7.8 0.0 3.1 3 0 0 3 3 3 0 mttA/Hcf106 family TNFR_c6 PF00020.18 PRP89314.1 - 2.1 8.8 10.5 0.66 10.4 0.5 3.0 2 1 0 2 2 2 0 TNFR/NGFR cysteine-rich region LRR_6 PF13516.6 PRP89315.1 - 6.8e-20 69.4 41.9 0.094 12.8 0.2 12.2 13 0 0 13 13 13 8 Leucine Rich repeat Mod_r PF07200.13 PRP89315.1 - 0.016 15.3 20.2 0.016 15.3 20.2 3.4 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein LRR_1 PF00560.33 PRP89315.1 - 2.2 9.2 13.3 63 4.7 0.0 7.3 9 0 0 9 9 9 0 Leucine Rich Repeat FUSC PF04632.12 PRP89315.1 - 3.3 6.1 9.6 6.6 5.1 9.6 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family CRAL_TRIO PF00650.20 PRP89317.1 - 1e-30 106.6 0.0 2.8e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PRP89317.1 - 1.1e-08 35.1 0.4 2.6e-08 33.9 0.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 PRP89317.1 - 0.034 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pox_D5 PF03288.16 PRP89317.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus D5 protein-like SH2 PF00017.24 PRP89319.1 - 4.8e-14 52.2 0.3 1.5e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 SH2 domain SH2_2 PF14633.6 PRP89319.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 SH2 domain BaffR-Tall_bind PF09256.10 PRP89319.1 - 0.084 12.6 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding Glyco_hydro81C PF17652.1 PRP89320.1 - 4e-79 266.4 0.2 6.7e-79 265.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 PRP89320.1 - 2.8e-36 125.3 4.8 2.8e-36 125.3 4.8 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 81 N-terminal domain Fascin PF06268.13 PRP89320.1 - 8.8e-09 35.6 4.4 0.0027 17.9 0.1 3.8 3 2 1 4 4 4 2 Fascin domain RicinB_lectin_2 PF14200.6 PRP89320.1 - 0.048 14.4 30.4 0.12 13.2 3.0 6.5 3 3 5 8 8 8 0 Ricin-type beta-trefoil lectin domain-like FRG1 PF06229.12 PRP89320.1 - 0.49 10.1 1.6 4 7.1 0.4 2.5 2 0 0 2 2 2 0 FRG1-like domain Glyco_hydro81C PF17652.1 PRP89321.1 - 3.8e-28 98.7 0.9 3.6e-26 92.3 0.3 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 PRP89321.1 - 8.2e-26 90.9 4.0 1.9e-25 89.7 3.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Fascin PF06268.13 PRP89321.1 - 3.9e-12 46.4 0.5 0.0029 17.8 0.0 4.0 3 2 1 4 4 4 3 Fascin domain FRG1 PF06229.12 PRP89321.1 - 6.4e-05 22.7 0.3 0.00033 20.4 0.1 2.2 2 0 0 2 2 2 1 FRG1-like domain RicinB_lectin_2 PF14200.6 PRP89321.1 - 0.0058 17.3 17.9 0.015 16.0 0.6 5.2 4 1 1 5 5 5 2 Ricin-type beta-trefoil lectin domain-like Ank_4 PF13637.6 PRP89322.1 - 4.7e-20 71.7 0.8 6.8e-10 39.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP89322.1 - 8e-20 70.3 0.2 4.4e-06 26.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 PRP89322.1 - 3.2e-19 69.3 0.0 5.3e-10 39.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PRP89322.1 - 2.1e-16 59.7 0.1 4.7e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP89322.1 - 2.8e-14 51.8 0.1 0.00016 21.8 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Peptidase_S41 PF03572.18 PRP89322.1 - 8e-13 48.3 0.0 3.4e-10 39.7 0.0 3.3 4 0 0 4 4 4 1 Peptidase family S41 Tricorn_C1 PF14684.6 PRP89322.1 - 0.00019 21.4 0.1 0.00038 20.5 0.1 1.5 1 0 0 1 1 1 1 Tricorn protease C1 domain TpcC PF12642.7 PRP89322.1 - 0.052 13.3 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Conjugative transposon protein TcpC PDZ_2 PF13180.6 PRP89322.1 - 0.06 13.7 0.6 2.7 8.4 0.1 2.9 2 0 0 2 2 2 0 PDZ domain PDZ_6 PF17820.1 PRP89322.1 - 0.079 12.8 0.0 5.7 6.9 0.0 2.8 2 0 0 2 2 2 0 PDZ domain Pap_E4 PF02711.14 PRP89322.1 - 0.17 12.8 0.3 50 4.9 0.0 2.7 2 0 0 2 2 2 0 E4 protein Pkinase_Tyr PF07714.17 PRP89323.1 - 5.9e-72 242.1 0.0 8.2e-72 241.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89323.1 - 6.6e-50 169.9 0.0 9.8e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP89323.1 - 1.1e-36 124.3 103.5 4.2e-09 36.0 2.8 12.9 8 3 5 13 13 13 8 Leucine rich repeat LRR_4 PF12799.7 PRP89323.1 - 3e-29 100.6 100.5 3.3e-05 24.1 0.1 14.3 7 3 9 17 17 17 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP89323.1 - 2.7e-09 36.3 72.3 0.35 11.6 0.1 20.4 18 4 2 20 20 19 1 Leucine Rich Repeat LRR_6 PF13516.6 PRP89323.1 - 1e-05 25.2 76.0 0.31 11.2 0.1 18.2 21 0 0 21 21 20 4 Leucine Rich repeat Pkinase_fungal PF17667.1 PRP89323.1 - 7.1e-05 21.7 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP89323.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PRP89323.1 - 0.0029 17.0 0.1 0.0055 16.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Podoplanin PF05808.11 PRP89323.1 - 0.0065 16.6 0.6 0.012 15.7 0.6 1.4 1 0 0 1 1 1 1 Podoplanin Rax2 PF12768.7 PRP89323.1 - 0.019 14.4 0.1 0.055 12.9 0.1 1.8 1 0 0 1 1 1 0 Cortical protein marker for cell polarity LRRNT_2 PF08263.12 PRP89323.1 - 0.034 14.4 1.1 0.084 13.2 1.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain DUF1180 PF06679.12 PRP89323.1 - 0.043 14.2 0.6 0.095 13.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) VSP PF03302.13 PRP89323.1 - 0.11 11.4 1.4 0.17 10.7 1.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein SET PF00856.28 PRP89324.1 - 3.5e-10 40.5 0.1 4.3e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 SET domain PAPA-1 PF04795.12 PRP89325.1 - 3.2e-11 43.9 5.3 3.2e-11 43.9 5.3 3.7 1 1 1 2 2 2 1 PAPA-1-like conserved region Phosphodiest PF01663.22 PRP89326.1 - 6.1e-09 35.9 0.9 3e-06 27.1 0.2 2.1 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PRP89326.1 - 0.0025 17.2 0.2 0.0075 15.7 0.0 1.8 1 1 1 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 PRP89326.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily FA_hydroxylase PF04116.13 PRP89327.1 - 4.2e-27 95.1 9.9 4.2e-27 95.1 9.9 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sigma_M_inh PF17453.2 PRP89328.1 - 0.056 13.9 1.3 0.095 13.2 0.1 2.0 2 1 1 3 3 3 0 Sigma-M inhibitor ADH_zinc_N PF00107.26 PRP89329.1 - 3.3e-29 101.5 0.3 5.1e-29 100.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PRP89329.1 - 3.3e-20 73.5 0.2 6.2e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PRP89329.1 - 2.5e-08 33.8 0.1 6e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 PRP89329.1 - 0.0059 15.9 0.1 0.0092 15.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 PRP89329.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Treslin_N PF15292.6 PRP89330.1 - 0.064 11.6 0.0 0.09 11.1 0.0 1.1 1 0 0 1 1 1 0 Treslin N-terminus Cyclin_N PF00134.23 PRP89331.1 - 5.7e-25 87.5 0.1 1.3e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PRP89331.1 - 1e-05 25.6 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF5395 PF17373.2 PRP89331.1 - 0.04 14.6 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5395) NmrA PF05368.13 PRP89333.1 - 2.1e-47 161.6 0.0 2.6e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PRP89333.1 - 8.6e-22 77.9 0.0 1.2e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PRP89333.1 - 3e-05 23.1 0.0 9.6e-05 21.5 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PRP89333.1 - 0.00086 18.8 0.1 0.073 12.5 0.0 2.5 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 PRP89333.1 - 0.0055 17.1 0.1 0.0087 16.5 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 PRP89333.1 - 0.0095 15.9 0.1 0.019 14.9 0.1 1.5 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 PRP89333.1 - 0.018 15.2 0.1 0.032 14.3 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 PRP89333.1 - 0.024 13.8 0.1 5.7 6.0 0.0 3.0 3 1 1 4 4 4 0 Male sterility protein TrkA_N PF02254.18 PRP89333.1 - 0.086 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ELMO_CED12 PF04727.13 PRP89334.1 - 4.6e-37 127.8 0.6 1.3e-18 67.8 0.0 2.2 2 0 0 2 2 2 2 ELMO/CED-12 family DUF1878 PF08963.10 PRP89334.1 - 0.082 13.4 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) TraV PF09676.10 PRP89335.1 - 0.057 14.4 0.5 0.057 14.4 0.5 1.7 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) PTPlike_phytase PF14566.6 PRP89336.1 - 1.1e-42 145.8 0.2 1.9e-42 145.0 0.2 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 PRP89336.1 - 0.0022 17.8 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain IQ_SEC7_PH PF16453.5 PRP89336.1 - 0.036 14.1 0.4 0.2 11.7 0.4 2.1 1 1 0 1 1 1 0 PH domain Y_phosphatase PF00102.27 PRP89336.1 - 0.071 12.7 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ras PF00071.22 PRP89337.1 - 1.6e-15 57.0 0.0 3.3e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89337.1 - 2e-12 47.4 2.0 1.1e-11 45.0 0.0 3.1 4 0 0 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89337.1 - 7.4e-10 38.5 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PRP89337.1 - 2.9e-06 26.8 0.0 8.1e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PRP89337.1 - 6.6e-06 26.2 0.0 2.6e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Forkhead_N PF08430.12 PRP89337.1 - 0.0032 18.1 18.9 0.0032 18.1 18.9 2.1 2 0 0 2 2 2 1 Forkhead N-terminal region SRPRB PF09439.10 PRP89337.1 - 0.0042 16.5 0.2 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PRP89337.1 - 0.0082 15.3 3.8 1.6 7.8 0.0 3.4 2 1 1 3 3 3 1 G-protein alpha subunit cobW PF02492.19 PRP89338.1 - 2.6e-50 170.4 0.9 4.6e-50 169.6 0.9 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain eIF3g PF12353.8 PRP89338.1 - 4.2e-29 101.5 6.0 1.1e-28 100.1 6.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G CobW_C PF07683.14 PRP89338.1 - 1.3e-20 73.1 0.0 3e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RRM_1 PF00076.22 PRP89338.1 - 1.6e-20 72.6 0.0 9.4e-20 70.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RsgA_GTPase PF03193.16 PRP89338.1 - 0.00063 19.7 0.2 0.86 9.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PRP89338.1 - 0.0039 17.6 0.1 0.0091 16.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain RRM_occluded PF16842.5 PRP89338.1 - 0.0046 16.8 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif TsaE PF02367.17 PRP89338.1 - 0.016 15.2 0.2 0.14 12.2 0.0 2.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PRP89338.1 - 0.13 12.5 0.2 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PRP89338.1 - 0.16 12.2 0.0 0.65 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PRP89338.1 - 0.17 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PRP89338.1 - 0.19 12.2 1.6 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PRP89338.1 - 1.4 9.4 3.7 1.3 9.5 0.7 2.5 2 1 0 2 2 2 0 ABC transporter Mpp10 PF04006.12 PRP89339.1 - 1.3e-104 350.9 54.7 2.1e-104 350.2 54.7 1.3 1 0 0 1 1 1 1 Mpp10 protein DHHC PF01529.20 PRP89340.1 - 8.5e-35 119.8 5.6 8.5e-35 119.8 5.6 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase PalH PF08733.10 PRP89340.1 - 9.7 5.1 13.3 0.43 9.5 2.9 2.4 2 1 0 2 2 2 0 PalH/RIM21 GRAM PF02893.20 PRP89342.1 - 2.3e-10 40.4 0.0 5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain LRR_8 PF13855.6 PRP89343.1 - 1.2e-15 57.0 24.7 6.2e-08 32.3 6.8 3.7 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PRP89343.1 - 1.6e-13 50.6 32.1 5.2e-08 33.1 2.2 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) zf-C3HC4_3 PF13920.6 PRP89343.1 - 1.8e-10 40.5 12.0 3.1e-10 39.8 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PRP89343.1 - 2.8e-06 27.1 12.4 5.1e-06 26.2 12.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 LRR_1 PF00560.33 PRP89343.1 - 0.00017 21.7 19.4 0.49 11.1 0.3 6.6 6 0 0 6 6 6 2 Leucine Rich Repeat zf-RING_5 PF14634.6 PRP89343.1 - 0.32 11.0 12.3 0.59 10.2 12.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain MORN PF02493.20 PRP89344.1 - 1.8e-22 77.8 35.3 2.3e-06 27.1 2.5 5.8 5 0 0 5 5 5 5 MORN repeat DHO_dh PF01180.21 PRP89345.1 - 1.4e-97 326.5 0.1 1.7e-97 326.2 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ABC1 PF03109.16 PRP89345.1 - 0.0051 17.0 0.1 0.012 15.8 0.1 1.6 1 0 0 1 1 1 1 ABC1 family FMN_dh PF01070.18 PRP89345.1 - 0.023 13.8 0.1 0.047 12.7 0.1 1.6 1 1 0 1 1 1 0 FMN-dependent dehydrogenase NMO PF03060.15 PRP89345.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase RIO1 PF01163.22 PRP89348.1 - 3.6e-45 153.9 0.0 8.1e-45 152.7 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 PRP89348.1 - 1.4e-32 111.7 0.1 2.9e-32 110.7 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 PRP89348.1 - 2.3e-08 34.2 0.7 0.00025 21.0 0.0 3.2 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP89348.1 - 7.6e-05 22.2 2.2 0.2 11.0 0.0 3.0 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family FAM176 PF14851.6 PRP89348.1 - 0.76 9.4 6.2 1.3 8.7 6.2 1.4 1 0 0 1 1 1 0 FAM176 family Spt5_N PF11942.8 PRP89348.1 - 1.1 10.3 11.2 2.1 9.4 11.2 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 PRP89348.1 - 4 7.9 13.8 12 6.4 13.8 1.8 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 PRP89348.1 - 4.1 6.7 9.0 0.18 11.1 0.8 2.7 3 1 0 3 3 3 0 Protein kinase domain Pkinase PF00069.25 PRP89349.1 - 1e-29 103.8 0.0 1.7e-29 103.0 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89349.1 - 2.1e-08 33.8 0.0 4.9e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PRP89349.1 - 0.03 13.7 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP89349.1 - 0.078 12.9 0.0 8.3 6.3 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4020 PF13212.6 PRP89349.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) PH PF00169.29 PRP89352.1 - 3.9e-08 33.8 0.3 6.7e-07 29.8 0.1 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 PRP89352.1 - 3 8.3 5.4 9.7 6.7 1.3 3.4 2 1 0 2 2 2 0 Pleckstrin homology domain Par3_HAL_N_term PF12053.8 PRP89353.1 - 0.00013 22.1 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins Cnd2 PF05786.14 PRP89354.1 - 1.6e-111 374.4 43.5 9.6e-109 365.2 43.5 3.5 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 PRP89354.1 - 2e-05 24.8 0.6 0.00011 22.4 0.6 2.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Ecm29 PF13001.7 PRP89356.1 - 5.3e-102 342.0 0.1 5.3e-102 342.0 0.1 4.2 4 2 0 4 4 4 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 PRP89356.1 - 8.4e-09 35.9 0.4 0.17 12.5 0.0 5.1 5 0 0 5 5 4 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 PRP89356.1 - 3.1e-07 30.7 1.9 0.15 12.5 0.0 7.0 7 1 0 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 PRP89356.1 - 1.5e-05 25.3 8.9 44 4.7 0.0 8.8 7 2 2 9 9 9 0 HEAT-like repeat HEAT PF02985.22 PRP89356.1 - 5.9e-05 23.0 8.9 1.2 9.6 0.0 9.4 11 0 0 11 11 9 1 HEAT repeat MMS19_C PF12460.8 PRP89356.1 - 0.02 14.1 11.7 2.1 7.4 1.1 5.7 5 1 0 5 5 5 0 RNAPII transcription regulator C-terminal ParcG PF10274.9 PRP89356.1 - 0.045 13.9 0.6 11 6.0 0.0 3.8 4 1 0 4 4 4 0 Parkin co-regulated protein Arm PF00514.23 PRP89356.1 - 0.1 12.7 0.1 11 6.2 0.0 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PA-IL PF07828.12 PRP89356.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 PA-IL-like protein IFRD PF05004.13 PRP89356.1 - 0.25 10.4 3.8 33 3.4 0.0 4.3 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 PRP89356.1 - 0.71 10.1 2.9 6.5 7.0 0.0 4.3 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4309 PF14172.6 PRP89357.1 - 0.00031 20.8 0.1 0.019 15.0 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4309) zf-rbx1 PF12678.7 PRP89359.1 - 1.2e-17 63.9 3.7 1.7e-17 63.5 3.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PRP89359.1 - 1.5e-09 37.7 3.9 2.6e-09 37.0 3.9 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 PRP89359.1 - 3.4e-08 33.7 3.0 5e-08 33.2 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PRP89359.1 - 7.4e-06 25.7 1.9 1.2e-05 25.1 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP89359.1 - 0.00025 20.9 2.9 0.00042 20.1 2.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PRP89359.1 - 0.004 16.9 4.0 0.0073 16.0 4.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PRP89359.1 - 0.025 14.6 2.0 0.042 13.9 2.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 PRP89359.1 - 0.027 14.1 5.4 0.047 13.3 5.4 1.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 PRP89359.1 - 0.068 13.4 1.8 0.11 12.7 1.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 PRP89359.1 - 0.083 13.1 4.4 0.11 12.7 3.2 1.7 1 1 1 2 2 2 0 Zinc-ribbon like family HAT_KAT11 PF08214.11 PRP89360.1 - 0.067 12.5 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Histone acetylation protein Prefoldin_2 PF01920.20 PRP89361.1 - 1.3e-18 66.9 5.7 2e-18 66.3 5.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 PRP89361.1 - 0.064 13.2 4.6 0.057 13.3 2.8 1.8 1 1 1 2 2 2 0 Prefoldin subunit FliD_C PF07195.12 PRP89361.1 - 0.14 11.5 5.6 0.15 11.4 3.0 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Spore_III_AB PF09548.10 PRP89361.1 - 0.4 10.8 3.9 1 9.5 3.9 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) ABC_tran_CTD PF16326.5 PRP89361.1 - 0.43 10.9 6.2 2.7 8.3 0.8 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Spc24 PF08286.11 PRP89361.1 - 0.45 10.8 11.1 9.2 6.6 11.1 2.4 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 YabA PF06156.13 PRP89361.1 - 1.4 9.6 6.7 0.32 11.6 0.3 2.3 2 1 0 2 2 2 0 Initiation control protein YabA GMC_oxred_N PF00732.19 PRP89362.1 - 2e-30 106.2 0.0 1.2e-29 103.7 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PRP89362.1 - 2.7e-10 40.9 0.0 5.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PRP89362.1 - 0.00016 21.9 0.0 0.00036 20.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PRP89362.1 - 0.03 13.4 0.1 0.077 12.1 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 PRP89362.1 - 0.036 13.7 0.1 0.15 11.6 0.0 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 PRP89362.1 - 0.2 10.3 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 PRP89362.1 - 0.21 10.8 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CarboxypepD_reg PF13620.6 PRP89363.1 - 1.4e-09 38.1 0.7 3.4e-09 36.9 0.7 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 PRP89363.1 - 0.00097 19.1 0.3 0.0023 17.9 0.2 1.7 2 0 0 2 2 2 1 CarboxypepD_reg-like domain DUF1263 PF06882.12 PRP89363.1 - 0.024 14.7 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) TIG PF01833.24 PRP89363.1 - 0.62 10.2 12.2 4.8 7.3 1.5 4.3 2 2 1 3 3 3 0 IPT/TIG domain Pkinase PF00069.25 PRP89366.1 - 4.5e-67 226.2 0.0 5.2e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89366.1 - 1.9e-42 145.3 0.0 2.3e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP89366.1 - 5.8e-10 39.0 0.0 6.5e-08 32.2 0.0 2.1 1 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 PRP89366.1 - 1.1e-06 28.2 0.7 1.5e-06 27.7 0.7 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PRP89366.1 - 2.3e-06 26.6 0.0 4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PRP89366.1 - 6.9e-05 22.9 0.1 9.9e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 PRP89366.1 - 7.7e-05 22.4 0.1 0.00011 21.9 0.1 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 PRP89366.1 - 0.0041 16.8 0.1 0.0093 15.6 0.0 1.6 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 PRP89366.1 - 0.018 14.0 0.4 0.03 13.3 0.4 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Myosin_head PF00063.21 PRP89367.1 - 1e-282 939.4 0.2 1e-282 939.4 0.2 2.8 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 PRP89367.1 - 1.3e-47 162.4 360.1 1.1e-14 53.3 166.6 6.4 1 1 4 5 5 5 5 Myosin tail Filament PF00038.21 PRP89367.1 - 8.4e-10 38.7 306.3 9.1e-05 22.2 46.4 14.1 1 1 8 9 9 9 6 Intermediate filament protein BST2 PF16716.5 PRP89367.1 - 0.00031 21.3 12.8 0.00031 21.3 12.8 18.2 3 3 16 20 20 20 1 Bone marrow stromal antigen 2 IQ PF00612.27 PRP89367.1 - 0.01 15.6 3.2 0.13 12.2 0.3 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif Myosin_N PF02736.19 PRP89367.1 - 0.044 13.6 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF3800 PF12686.7 PRP89367.1 - 0.063 13.9 26.2 7.2e+03 -2.4 0.9 8.7 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) Acetyltransf_CG PF14542.6 PRP89368.1 - 8.8e-20 70.6 0.0 1.6e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Homeobox_KN PF05920.11 PRP89369.1 - 1.8e-17 62.9 0.7 3.6e-17 62.0 0.7 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 PRP89369.1 - 2.7e-05 23.9 0.0 9.3e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 Homeodomain SIP1 PF04938.12 PRP89370.1 - 8.8e-39 133.5 11.0 1.1e-37 129.9 11.0 2.0 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) SAP PF02037.27 PRP89371.1 - 9.5e-13 47.6 0.7 1.6e-12 46.8 0.7 1.4 1 0 0 1 1 1 1 SAP domain Vac14_Fig4_bd PF11916.8 PRP89372.1 - 1.3e-61 207.3 11.1 3.2e-61 206.1 11.1 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 PRP89372.1 - 3.5e-47 158.9 0.2 8.7e-41 138.4 0.1 5.3 2 1 3 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 PRP89372.1 - 1.7e-10 40.2 0.1 0.001 19.1 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 PRP89372.1 - 3e-09 37.2 0.0 0.0013 19.2 0.0 4.8 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.7 PRP89372.1 - 1e-06 28.9 4.8 0.18 11.8 1.0 3.6 3 0 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Dopey_N PF04118.14 PRP89372.1 - 5.2e-06 25.8 2.5 3.9e-05 22.9 0.4 3.2 2 1 1 3 3 3 1 Dopey, N-terminal HEAT_2 PF13646.6 PRP89372.1 - 0.0071 16.7 0.0 2.4 8.6 0.0 4.0 4 1 0 4 4 4 1 HEAT repeats Stork_head PF10264.9 PRP89372.1 - 0.015 15.5 0.4 30 4.9 0.0 3.6 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain Arm PF00514.23 PRP89372.1 - 0.13 12.3 0.1 3.5 7.8 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PPL4 PF18188.1 PRP89372.1 - 0.57 10.1 3.3 0.44 10.5 0.1 2.1 2 0 0 2 2 2 0 Prim-pol 4 WH2 PF02205.20 PRP89373.1 - 1.3e-09 37.5 1.1 0.00026 20.7 0.1 3.4 3 0 0 3 3 3 3 WH2 motif Thymosin PF01290.20 PRP89373.1 - 0.17 11.6 1.0 7 6.5 0.1 2.7 2 1 0 2 2 2 0 Thymosin beta-4 family IF4E PF01652.18 PRP89375.1 - 4.5e-28 98.0 0.5 7.2e-28 97.4 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cript PF10235.9 PRP89376.1 - 0.052 14.1 0.6 0.07 13.7 0.6 1.2 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Cytochrom_c3_2 PF14537.6 PRP89376.1 - 0.062 13.8 0.1 0.076 13.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome c3 Rdx PF10262.9 PRP89376.1 - 0.11 12.8 0.6 0.12 12.6 0.0 1.5 2 0 0 2 2 2 0 Rdx family TMEM171 PF15471.6 PRP89377.1 - 7.1 5.5 5.9 59 2.5 5.9 2.4 1 1 0 1 1 1 0 Transmembrane protein family 171 Pyrid_ox_like PF16242.5 PRP89379.1 - 5.9e-37 126.5 0.0 7.8e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 PRP89379.1 - 2.6e-11 43.5 0.0 9.5e-11 41.8 0.0 1.9 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Sad1_UNC PF07738.13 PRP89380.1 - 1.4e-31 109.2 0.0 3.3e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Baculo_PEP_C PF04513.12 PRP89380.1 - 0.036 14.1 9.2 1.3 9.0 0.0 3.5 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4175 PF13779.6 PRP89380.1 - 1.8 6.3 39.2 5.1 4.9 39.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) CLU PF13236.6 PRP89382.1 - 5.2e-41 140.9 0.0 2.7e-40 138.6 0.0 2.2 3 0 0 3 3 3 1 Clustered mitochondria eIF3_p135 PF12807.7 PRP89382.1 - 1.2e-06 28.7 0.1 3e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 LRR_4 PF12799.7 PRP89382.1 - 3.3e-06 27.3 21.8 1 9.9 0.0 9.5 6 2 3 9 9 9 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP89382.1 - 1.4e-05 24.8 17.0 9.7 6.5 0.0 11.0 14 0 0 14 14 14 2 Leucine Rich repeat TPR_11 PF13414.6 PRP89382.1 - 0.014 15.0 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Homeodomain PF00046.29 PRP89383.1 - 9.7e-12 44.6 0.7 2.3e-11 43.4 0.7 1.6 1 0 0 1 1 1 1 Homeodomain Forkhead PF00250.18 PRP89383.1 - 1.4e-10 41.3 0.1 5e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Forkhead domain Homeobox_KN PF05920.11 PRP89383.1 - 4.5e-07 29.6 0.0 1.2e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain DUF21 PF01595.20 PRP89386.1 - 3.6e-34 118.0 0.2 6.2e-34 117.2 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 PRP89386.1 - 1.7e-06 28.4 0.9 0.021 15.3 0.0 2.9 2 0 0 2 2 2 2 CBS domain LMSTEN PF07988.12 PRP89386.1 - 0.02 14.4 0.5 0.045 13.2 0.5 1.6 1 0 0 1 1 1 0 LMSTEN motif GATase PF00117.28 PRP89386.1 - 0.17 11.7 0.0 4.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase class-I Glyco_hydro_72 PF03198.14 PRP89387.1 - 3.6e-94 315.6 0.0 9.5e-94 314.2 0.0 1.7 1 0 0 1 1 1 1 Glucanosyltransferase Melibiase_2 PF16499.5 PRP89387.1 - 2.1e-71 240.4 5.1 5.1e-71 239.2 2.8 2.2 2 0 0 2 2 2 1 Alpha galactosidase A Asp PF00026.23 PRP89387.1 - 8.9e-18 64.8 0.0 1.7e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease X8 PF07983.13 PRP89387.1 - 2.9e-16 59.9 1.1 7.5e-16 58.6 1.1 1.7 1 0 0 1 1 1 1 X8 domain Melibiase_C PF17801.1 PRP89387.1 - 2.5e-12 46.7 0.0 1.6e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain TAXi_N PF14543.6 PRP89387.1 - 1e-09 38.9 0.0 3.2e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Melibiase PF02065.18 PRP89387.1 - 1.5e-05 24.1 0.0 3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Melibiase PA PF02225.22 PRP89387.1 - 0.0054 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 PA domain Melibiase_2_C PF17450.2 PRP89387.1 - 0.018 15.2 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain TAXi_C PF14541.6 PRP89387.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 PRP89387.1 - 0.08 13.5 0.1 69 4.1 0.0 3.7 3 1 1 4 4 4 0 gag-polyprotein putative aspartyl protease Carb_bind PF10645.9 PRP89387.1 - 0.46 10.7 4.1 1.8 8.8 4.1 2.1 1 0 0 1 1 1 0 Carbohydrate binding F-box-like PF12937.7 PRP89388.1 - 4.6e-09 36.0 2.2 1.1e-08 34.9 2.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 PRP89388.1 - 5.8e-09 36.5 9.0 0.056 14.3 3.1 5.5 4 1 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.33 PRP89388.1 - 2.9e-06 27.0 1.6 7.8e-06 25.6 1.6 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP89388.1 - 0.00012 21.9 0.8 0.00029 20.7 0.8 1.6 1 0 0 1 1 1 1 F-box ANAPC4_WD40 PF12894.7 PRP89388.1 - 0.00033 20.9 1.3 0.068 13.5 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain 3HCDH_N PF02737.18 PRP89390.1 - 7.9e-53 179.0 0.2 1.7e-52 177.9 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 PRP89390.1 - 8.1e-44 149.8 0.1 1.2e-43 149.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PRP89390.1 - 7.8e-32 111.1 0.0 1.6e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 PRP89390.1 - 2.1e-29 102.0 0.0 6.4e-24 84.4 0.1 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain OCD_Mu_crystall PF02423.15 PRP89390.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF3088 PF11287.8 PRP89390.1 - 0.085 12.6 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) Peptidase_S49 PF01343.18 PRP89390.1 - 0.09 12.7 0.2 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Peptidase family S49 YjcZ PF13990.6 PRP89390.1 - 0.22 10.9 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 YjcZ-like protein Aldedh PF00171.22 PRP89391.1 - 2.6e-82 276.8 0.0 2.9e-82 276.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 PRP89391.1 - 8.9e-09 34.9 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) GWT1 PF06423.12 PRP89392.1 - 4.1e-28 98.4 8.3 2.9e-27 95.6 5.4 2.8 2 1 0 2 2 2 1 GWT1 DUF962 PF06127.11 PRP89392.1 - 0.015 15.4 0.0 0.048 13.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DHC_N2 PF08393.13 PRP89393.1 - 7.5e-86 288.7 9.6 7.5e-86 288.7 9.6 2.9 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 PRP89393.1 - 3e-51 173.7 4.1 2e-47 161.2 0.0 4.5 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_6 PF12774.7 PRP89393.1 - 4.3e-45 154.1 0.0 1.7e-44 152.1 0.0 2.1 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 PRP89393.1 - 4.6e-40 137.6 0.0 2.6e-38 131.9 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PRP89393.1 - 5.2e-35 121.1 1.5 1.2e-34 119.9 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 PRP89393.1 - 3.7e-30 105.1 5.7 6.6e-30 104.3 5.7 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 PRP89393.1 - 1.7e-25 89.5 0.1 2.3e-22 79.3 0.1 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 PRP89393.1 - 2.1e-21 76.4 0.0 5.2e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 PRP89393.1 - 4e-17 62.3 0.5 4.9e-14 52.2 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 PRP89393.1 - 3.6e-12 46.5 0.0 1.6e-11 44.4 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PRP89393.1 - 1.6e-07 31.4 0.0 0.001 19.1 0.0 5.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PRP89393.1 - 0.00012 22.3 0.0 0.0098 16.2 0.0 3.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PRP89393.1 - 0.00038 20.9 0.1 0.18 12.1 0.0 4.3 4 0 0 4 4 3 1 AAA ATPase domain Roc PF08477.13 PRP89393.1 - 0.0021 18.2 0.2 0.015 15.5 0.0 2.7 3 0 0 3 3 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PRP89393.1 - 0.0029 17.6 1.5 0.014 15.3 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 PRP89393.1 - 0.0083 16.6 4.5 0.0083 16.6 0.0 3.3 3 0 0 3 3 2 1 ABC transporter Rad17 PF03215.15 PRP89393.1 - 0.013 15.5 0.0 0.059 13.3 0.0 2.2 2 0 0 2 2 1 0 Rad17 P-loop domain Ras PF00071.22 PRP89393.1 - 0.014 15.0 0.0 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 Ras family AAA_33 PF13671.6 PRP89393.1 - 0.017 15.3 0.0 0.076 13.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_lid_1 PF17857.1 PRP89393.1 - 0.025 14.8 0.0 0.13 12.5 0.0 2.2 1 0 0 1 1 1 0 AAA+ lid domain AAA_14 PF13173.6 PRP89393.1 - 0.041 13.9 0.1 1.6 8.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 PRP89393.1 - 0.08 13.3 0.0 1.4 9.4 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 PRP89393.1 - 0.11 13.1 1.9 3.1 8.4 0.0 4.1 5 0 0 5 5 3 0 AAA domain AAA PF00004.29 PRP89393.1 - 0.13 12.6 1.6 1.4 9.3 0.0 3.7 5 0 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PRP89393.1 - 0.15 12.3 0.0 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP89393.1 - 0.17 11.6 0.0 0.51 10.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arg_decarbox_C PF17944.1 PRP89393.1 - 0.38 11.4 1.3 2.8 8.6 0.0 3.0 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension AAA_23 PF13476.6 PRP89393.1 - 2.1 8.8 0.0 2.1 8.8 0.0 5.6 5 1 0 5 5 4 0 AAA domain HA PF03457.14 PRP89394.1 - 3.4e-16 59.3 3.3 1e-15 57.8 3.3 1.8 1 0 0 1 1 1 1 Helicase associated domain DBC1 PF14443.6 PRP89394.1 - 9.7e-05 22.3 0.4 0.95 9.5 0.0 3.2 3 0 0 3 3 3 2 DBC1 Pkinase PF00069.25 PRP89395.1 - 4.1e-58 196.8 0.1 4.9e-58 196.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89395.1 - 1.1e-17 64.2 0.0 1.5e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP89395.1 - 7.7e-06 26.0 0.1 5.6e-05 23.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PRP89395.1 - 0.0049 15.7 0.0 0.0085 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP89395.1 - 0.055 12.8 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PRP89395.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 PRP89396.1 - 6.1e-57 193.0 0.0 7.4e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89396.1 - 1.8e-29 102.8 0.0 2.7e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PRP89396.1 - 0.00026 21.0 0.0 0.0056 16.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP89396.1 - 0.00038 19.9 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HATPase_c PF02518.26 PRP89397.1 - 2.3e-29 102.1 0.0 7.9e-29 100.4 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 PRP89397.1 - 3.6e-27 94.6 0.1 3.8e-13 49.4 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 PRP89397.1 - 3.2e-26 91.7 0.0 3.3e-09 37.0 0.0 3.5 3 1 0 3 3 3 3 PAS fold Response_reg PF00072.24 PRP89397.1 - 3.4e-25 88.4 0.0 6.8e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 PRP89397.1 - 1.2e-23 83.3 0.0 1.5e-10 41.2 0.0 3.1 3 0 0 3 3 3 2 PAS domain HisKA PF00512.25 PRP89397.1 - 2e-18 66.1 0.0 4.7e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 PRP89397.1 - 4.4e-10 39.7 0.0 6.8e-07 29.5 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 PRP89397.1 - 1.1e-07 31.7 0.0 0.0097 15.9 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_7 PF12860.7 PRP89397.1 - 0.00017 21.7 0.3 0.018 15.2 0.1 3.4 2 1 1 3 3 3 1 PAS fold HATPase_c_3 PF13589.6 PRP89397.1 - 0.096 12.5 0.1 0.46 10.3 0.1 2.1 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_10 PF13596.6 PRP89397.1 - 0.1 13.2 0.0 1.3 9.7 0.0 2.6 2 0 0 2 2 2 0 PAS domain Cyt-b5 PF00173.28 PRP89398.1 - 2.3e-21 75.7 0.1 3.8e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CDGSH PF09360.10 PRP89398.1 - 8.6e-07 29.1 0.1 2.3e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Herpes_LP PF03363.13 PRP89398.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus leader protein PPV_E2_N PF00508.17 PRP89398.1 - 0.074 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 E2 (early) protein, N terminal Pkinase PF00069.25 PRP89399.1 - 1.2e-65 221.5 0.1 1.7e-65 221.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89399.1 - 1e-45 156.0 0.1 1.8e-45 155.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 PRP89399.1 - 1.3e-18 67.4 0.1 3.6e-18 66.0 0.1 1.8 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 PRP89399.1 - 4.8e-06 25.6 0.0 8.5e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP89399.1 - 0.001 18.5 0.0 0.0025 17.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like PBD PF00786.28 PRP89399.1 - 0.0023 18.3 0.2 0.019 15.3 0.1 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Haspin_kinase PF12330.8 PRP89399.1 - 0.0077 15.2 0.3 0.037 13.0 0.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain PH_8 PF15409.6 PRP89399.1 - 0.11 12.8 1.0 0.37 11.1 0.2 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 PRP89399.1 - 0.12 12.8 3.1 0.46 10.9 3.1 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain SH2 PF00017.24 PRP89400.1 - 2.9e-22 78.5 0.0 9.1e-11 41.7 0.0 2.5 2 0 0 2 2 2 2 SH2 domain Cbl_N2 PF02761.14 PRP89400.1 - 4.8e-11 43.2 0.0 1.3e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2_2 PF14633.6 PRP89400.1 - 0.0091 15.4 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 SH2 domain AMP-binding PF00501.28 PRP89401.1 - 1.2e-81 274.5 0.0 1.5e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP89401.1 - 4.2e-24 85.3 0.6 7.8e-24 84.5 0.6 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 PRP89401.1 - 8.9e-23 80.0 1.9 2.5e-22 78.6 1.9 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus WD40 PF00400.32 PRP89403.1 - 2e-12 47.4 12.6 2.7e-05 24.9 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP89403.1 - 8e-07 29.3 0.1 0.0055 17.0 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 PRP89403.1 - 0.0042 16.5 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 PRP89403.1 - 0.048 13.2 0.2 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 PQQ-like domain Spermine_synth PF01564.17 PRP89404.1 - 3.6e-64 215.6 0.0 6.7e-64 214.8 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PRP89404.1 - 1.4e-19 69.7 0.0 2.7e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 PRP89404.1 - 5.2e-06 27.1 0.0 1.3e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PRP89404.1 - 0.0018 19.0 0.1 0.012 16.3 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PRP89404.1 - 0.0055 16.3 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PRP89404.1 - 0.012 15.5 0.0 0.051 13.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 PRP89404.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Ribosomal_S21e PF01249.18 PRP89405.1 - 2.4e-40 136.5 0.0 2.7e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e OCD_Mu_crystall PF02423.15 PRP89406.1 - 7e-62 209.2 1.3 8.2e-62 209.0 1.3 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family LSM PF01423.22 PRP89406.1 - 1.7e-20 72.5 0.0 4.2e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 LSM domain Shikimate_DH PF01488.20 PRP89406.1 - 5.4e-13 49.2 0.1 9.7e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SM-ATX PF14438.6 PRP89406.1 - 0.049 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain LRR_6 PF13516.6 PRP89407.1 - 6.5e-07 28.9 20.9 0.84 9.8 0.4 8.6 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 PRP89407.1 - 6.6e-06 26.4 26.9 0.078 13.4 3.5 8.0 7 1 3 10 10 10 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PRP89407.1 - 8.2e-05 22.4 0.1 0.0002 21.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP89407.1 - 0.00043 20.1 0.2 0.0017 18.2 0.1 2.1 1 1 1 2 2 2 1 F-box domain LRR_8 PF13855.6 PRP89407.1 - 0.014 15.2 10.9 1.1 9.1 3.2 5.4 3 2 1 4 4 4 0 Leucine rich repeat SAM_Ste50p PF09235.10 PRP89407.1 - 0.72 10.1 6.7 27 5.1 0.1 4.7 3 1 1 4 4 4 0 Ste50p, sterile alpha motif LRR_1 PF00560.33 PRP89407.1 - 5.5 7.9 19.9 15 6.6 0.2 8.2 7 2 0 7 7 7 0 Leucine Rich Repeat LicD PF04991.13 PRP89408.1 - 1.5e-20 74.3 3.5 1.4e-15 58.1 0.4 2.7 2 1 0 3 3 3 2 LicD family Peptidase_A4 PF01828.17 PRP89409.1 - 0.0085 15.6 1.3 0.016 14.7 1.3 1.4 1 0 0 1 1 1 1 Peptidase A4 family HA PF03457.14 PRP89411.1 - 7.4e-42 141.5 16.4 2.4e-19 69.4 0.8 4.0 5 0 0 5 5 5 3 Helicase associated domain bVLRF1 PF18826.1 PRP89411.1 - 0.016 15.1 0.8 0.24 11.2 0.3 2.5 2 0 0 2 2 2 0 bacteroidetes VLRF1 release factor YvbH_ext PF11724.8 PRP89411.1 - 2.4 8.6 6.7 12 6.3 0.0 4.2 4 0 0 4 4 4 0 YvbH-like oligomerisation region ASCH PF04266.14 PRP89412.1 - 1.3e-07 32.1 0.0 2.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 ASCH domain DUF202 PF02656.15 PRP89412.1 - 0.0055 17.1 7.8 1.8 9.1 6.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF202) MFS_Mycoplasma PF07672.13 PRP89412.1 - 0.073 12.4 0.1 0.073 12.4 0.1 2.2 3 0 0 3 3 3 0 Mycoplasma MFS transporter DUF4231 PF14015.6 PRP89412.1 - 8.2 7.0 6.9 4.3 7.9 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Amino_oxidase PF01593.24 PRP89413.1 - 3.9e-60 204.4 0.0 1.2e-41 143.5 0.0 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP89413.1 - 5.7e-15 55.3 0.2 1.3e-14 54.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PRP89413.1 - 1.7e-06 27.4 0.3 3.2e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 PRP89413.1 - 1.4e-05 24.9 0.1 5.7e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PRP89413.1 - 0.00054 19.3 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 PRP89413.1 - 0.0019 18.2 0.1 0.0038 17.2 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 PRP89413.1 - 0.0051 16.1 0.0 0.0083 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PRP89413.1 - 0.016 14.3 0.2 0.033 13.3 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 PRP89413.1 - 0.018 13.7 0.6 0.033 12.9 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 PRP89413.1 - 0.058 14.0 0.6 0.18 12.3 0.6 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3782 PF12644.7 PRP89413.1 - 0.14 12.4 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) adh_short PF00106.25 PRP89414.1 - 3.7e-22 78.7 0.0 5.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PRP89414.1 - 5.6e-09 35.9 0.0 7.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cmc1 PF08583.10 PRP89415.1 - 2.2e-13 50.0 2.7 2.5e-13 49.9 2.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 PRP89415.1 - 0.00033 20.3 2.7 0.00039 20.1 2.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 PRP89415.1 - 0.00033 21.0 0.6 0.0004 20.7 0.6 1.1 1 0 0 1 1 1 1 GCK domain DUF2087 PF09860.9 PRP89416.1 - 0.46 10.7 5.9 0.27 11.4 0.9 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) DivIC PF04977.15 PRP89416.1 - 1.5 8.6 35.4 0.51 10.1 0.2 5.6 4 1 1 5 5 5 0 Septum formation initiator DUF812 PF05667.11 PRP89416.1 - 6.5 5.5 45.5 0.42 9.5 12.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) VbhA PF18495.1 PRP89417.1 - 0.076 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Antitoxin VbhA DBC1 PF14443.6 PRP89418.1 - 3.7e-23 81.9 0.8 5.6e-22 78.0 0.0 2.6 2 0 0 2 2 2 1 DBC1 EF-hand_6 PF13405.6 PRP89418.1 - 0.031 14.2 0.1 0.099 12.6 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 PRP89418.1 - 0.091 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 EF hand Tubulin_3 PF14881.6 PRP89418.1 - 3.4 7.3 5.6 5.8 6.6 0.2 2.8 2 0 0 2 2 2 0 Tubulin domain Pkinase_Tyr PF07714.17 PRP89419.1 - 7.1e-73 245.1 0.0 9.9e-73 244.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89419.1 - 3.8e-51 174.0 0.0 5.5e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP89419.1 - 1.2e-45 153.1 107.2 4.6e-08 32.7 5.0 16.2 9 4 8 18 18 18 13 Leucine rich repeat LRR_4 PF12799.7 PRP89419.1 - 1.9e-40 136.2 109.9 0.00046 20.5 0.7 19.1 11 5 7 19 19 19 18 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP89419.1 - 3.8e-08 32.8 100.4 0.33 11.7 0.0 27.3 28 4 1 29 29 29 2 Leucine Rich Repeat LRR_6 PF13516.6 PRP89419.1 - 1.8e-06 27.6 107.3 1.3 9.3 0.5 25.6 29 0 0 29 29 28 5 Leucine Rich repeat SKG6 PF08693.10 PRP89419.1 - 0.00013 21.3 1.2 0.00024 20.5 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kdo PF06293.14 PRP89419.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glycophorin_A PF01102.18 PRP89419.1 - 0.059 13.6 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Glycophorin A Amnionless PF14828.6 PRP89419.1 - 0.17 10.7 0.1 0.26 10.1 0.1 1.2 1 0 0 1 1 1 0 Amnionless Pkinase_fungal PF17667.1 PRP89419.1 - 0.21 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Cmc1 PF08583.10 PRP89422.1 - 0.0058 16.6 2.1 0.0058 16.6 2.1 2.6 2 1 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 PRP89422.1 - 0.017 15.2 0.7 0.1 12.7 0.3 2.3 2 0 0 2 2 2 0 CHCH domain NDUF_B7 PF05676.13 PRP89422.1 - 0.11 12.2 5.3 0.071 12.8 2.6 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) ANF_receptor PF01094.28 PRP89422.1 - 0.2 10.7 0.2 0.25 10.4 0.2 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region MMR_HSR1_C PF08438.10 PRP89423.1 - 2.5e-38 131.1 0.0 3.8e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 PRP89423.1 - 2.4e-21 75.9 0.0 1.2e-20 73.7 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PRP89423.1 - 2.5e-09 36.9 0.1 1.3e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Hpr_kinase_N PF02603.16 PRP89423.1 - 0.0022 18.0 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 HPr Serine kinase N terminus TGS PF02824.21 PRP89423.1 - 0.0069 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.23 PRP89423.1 - 0.031 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Dynamin family HMG_box PF00505.19 PRP89424.1 - 1e-14 54.7 9.3 2.8e-12 46.9 1.4 3.4 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 PRP89424.1 - 6.1e-10 39.6 6.2 1.8e-07 31.6 0.4 3.2 2 2 1 3 3 3 2 HMG-box domain DUF5113 PF17140.4 PRP89424.1 - 0.13 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) CLN3 PF02487.17 PRP89424.1 - 2.3 7.2 8.4 0.11 11.6 1.7 1.8 1 1 1 2 2 2 0 CLN3 protein DUF3417 PF11897.8 PRP89424.1 - 2.9 8.4 8.9 0.22 12.0 2.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) DUF3987 PF13148.6 PRP89424.1 - 7.4 5.5 15.4 1.4 7.9 11.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) WD40 PF00400.32 PRP89425.1 - 1.9e-08 34.8 2.4 0.006 17.4 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP89425.1 - 0.0054 17.0 0.3 0.74 10.2 0.0 3.4 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 PRP89425.1 - 0.018 14.4 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region GOLD_2 PF13897.6 PRP89425.1 - 0.053 14.0 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Ge1_WD40 PF16529.5 PRP89425.1 - 0.11 11.4 0.1 7.3 5.4 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CH PF00307.31 PRP89427.1 - 7.3e-29 100.1 0.2 4e-13 49.5 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP89427.1 - 0.00023 20.9 0.0 0.036 13.9 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain Peripla_BP_2 PF01497.18 PRP89428.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Ribonuclease_3 PF00636.26 PRP89429.1 - 7e-49 164.8 0.0 4e-25 88.5 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 PRP89429.1 - 2.4e-29 102.1 0.0 1.6e-15 57.4 0.0 3.6 2 1 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 PRP89429.1 - 4.7e-19 68.8 0.0 1.2e-18 67.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP89429.1 - 2.9e-13 50.2 0.0 1.3e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 PRP89429.1 - 3.2e-13 49.6 0.0 8.9e-13 48.2 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 PRP89429.1 - 9.5e-12 45.0 0.1 2.9e-09 36.9 0.0 3.7 3 2 1 4 4 4 1 DEAD/DEAH box helicase DUF3638 PF12340.8 PRP89429.1 - 0.037 13.3 2.7 0.28 10.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3638) Flavi_DEAD PF07652.14 PRP89429.1 - 0.079 12.9 0.3 8.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain FHA_2 PF17913.1 PRP89431.1 - 0.017 15.4 0.1 4.5 7.6 0.1 3.0 2 1 0 2 2 2 0 FHA domain Peptidase_M1_N PF17900.1 PRP89432.1 - 3.7e-25 89.2 0.1 8.1e-25 88.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 PRP89432.1 - 3.6e-20 72.5 0.0 5.8e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain DA1-like PF12315.8 PRP89432.1 - 0.03 13.7 0.8 0.048 13.0 0.8 1.2 1 0 0 1 1 1 0 Protein DA1 DUF3196 PF11428.8 PRP89432.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) Peptidase_C48 PF02902.19 PRP89434.1 - 1.5e-18 67.4 0.3 4.2e-18 66.0 0.3 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain adh_short_C2 PF13561.6 PRP89435.1 - 6.4e-45 153.5 0.3 8.9e-45 153.1 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP89435.1 - 1.4e-44 151.9 0.2 2.6e-44 151.0 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP89435.1 - 4.5e-08 33.2 0.1 8.1e-08 32.4 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PRP89435.1 - 0.00079 19.0 0.0 0.0077 15.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 PRP89435.1 - 0.045 13.8 0.4 0.075 13.1 0.4 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Usp PF00582.26 PRP89436.1 - 0.0007 20.1 0.2 0.011 16.3 0.2 2.3 1 1 0 1 1 1 1 Universal stress protein family FancD2 PF14631.6 PRP89437.1 - 6.7e-128 428.1 37.5 6.3e-49 166.4 3.1 6.1 3 2 3 6 6 6 4 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 PRP89437.1 - 9.9e-05 22.7 0.1 9.9e-05 22.7 0.1 4.1 4 1 0 4 4 4 1 FANCI solenoid 2 CDC45 PF02724.14 PRP89437.1 - 0.00021 19.8 34.9 0.00021 19.8 34.9 1.9 2 0 0 2 2 2 1 CDC45-like protein Mitofilin PF09731.9 PRP89437.1 - 1.4 7.7 54.8 2.8 6.7 54.8 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.7 PRP89437.1 - 1.9 6.6 30.8 3.5 5.7 30.8 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CCSAP PF15748.5 PRP89437.1 - 5.9 7.0 45.4 16 5.6 45.4 1.7 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Neur_chan_memb PF02932.16 PRP89437.1 - 9.5 6.2 19.9 35 4.3 19.9 2.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ras PF00071.22 PRP89438.1 - 4e-55 185.8 0.5 5.3e-55 185.4 0.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89438.1 - 8.6e-35 119.6 0.3 1.4e-34 118.9 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89438.1 - 3.1e-14 52.8 0.1 4.5e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family U-box PF04564.15 PRP89438.1 - 3.5e-12 46.3 0.1 1.1e-11 44.8 0.1 1.8 1 0 0 1 1 1 1 U-box domain MMR_HSR1 PF01926.23 PRP89438.1 - 1e-05 25.5 0.1 1.9e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PRP89438.1 - 1.9e-05 24.2 0.1 3.1e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PRP89438.1 - 3.3e-05 23.5 0.6 0.00054 19.5 0.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 PRP89438.1 - 0.00017 21.4 0.0 0.055 13.2 0.0 2.4 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 PRP89438.1 - 0.00017 21.5 0.2 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase zf-Nse PF11789.8 PRP89438.1 - 0.00074 19.3 0.0 0.0024 17.7 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Gtr1_RagA PF04670.12 PRP89438.1 - 0.012 14.9 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 PRP89438.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MCM PF00493.23 PRP89438.1 - 0.028 13.5 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 PRP89438.1 - 0.029 14.7 0.0 0.1 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PRP89438.1 - 0.033 14.6 0.0 0.092 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 PRP89438.1 - 0.034 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DLIC PF05783.11 PRP89438.1 - 0.059 12.2 0.1 0.16 10.8 0.0 1.6 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) zf-RING_UBOX PF13445.6 PRP89438.1 - 0.068 13.2 0.1 0.31 11.1 0.0 2.2 3 0 0 3 3 1 0 RING-type zinc-finger AAA_24 PF13479.6 PRP89438.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-NOSIP PF15906.5 PRP89438.1 - 0.1 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein RNA_helicase PF00910.22 PRP89438.1 - 0.14 12.6 0.0 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA helicase FeoB_N PF02421.18 PRP89438.1 - 0.16 11.5 0.1 1.6 8.3 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B Mto2_bdg PF12808.7 PRP89438.1 - 1.9 8.9 8.1 0.15 12.3 2.9 1.9 2 0 0 2 2 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Pyr_redox_2 PF07992.14 PRP89439.1 - 2.2e-11 43.5 0.0 3e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 PRP89439.1 - 0.11 12.9 0.0 1.4 9.4 0.1 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding BMP2K_C PF15282.6 PRP89439.1 - 0.13 12.1 3.4 0.29 11.0 0.8 2.1 2 0 0 2 2 2 0 BMP-2-inducible protein kinase C-terminus NAD_binding_9 PF13454.6 PRP89439.1 - 0.14 12.1 0.0 2.6 8.0 0.0 2.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 PRP89439.1 - 0.24 12.0 0.9 6.7 7.3 0.1 3.5 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-H2C2_2 PF13465.6 PRP89441.1 - 6e-13 48.6 8.5 4.5e-07 30.0 1.9 3.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 PRP89441.1 - 1.8e-12 46.9 16.3 8.2e-06 26.0 0.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 PRP89441.1 - 1.2e-09 38.2 15.3 0.0072 17.1 0.6 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 PRP89441.1 - 0.00037 20.7 6.7 0.023 15.0 2.7 2.3 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 PRP89441.1 - 0.0015 18.7 3.9 0.11 12.9 0.0 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PRP89441.1 - 0.034 14.5 5.3 0.086 13.3 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 PRP89441.1 - 0.059 13.4 13.0 0.42 10.7 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger C1_4 PF07975.12 PRP89441.1 - 8.2 6.7 6.5 16 5.8 2.4 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain SBP_bac_10 PF07596.11 PRP89442.1 - 0.031 14.2 0.8 0.043 13.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) MGDG_synth PF06925.11 PRP89443.1 - 2.9e-23 82.8 0.3 2.1e-22 80.0 0.1 2.4 2 0 0 2 2 2 1 Monogalactosyldiacylglycerol (MGDG) synthase Glycos_transf_1 PF00534.20 PRP89443.1 - 2.3e-13 50.0 0.1 4.4e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tran_28_C PF04101.16 PRP89443.1 - 1.9e-06 28.0 0.4 5.6e-06 26.4 0.4 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 PRP89443.1 - 9.8e-06 26.0 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 PRP89443.1 - 0.034 13.0 0.0 0.09 11.6 0.0 1.6 1 1 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase BolA PF01722.18 PRP89444.1 - 6.2e-18 64.9 0.0 7.2e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein CBM_20 PF00686.19 PRP89445.1 - 6.7e-18 64.4 0.8 1.9e-17 63.0 0.0 2.1 3 0 0 3 3 3 1 Starch binding domain Alpha-amylase PF00128.24 PRP89445.1 - 2.2e-13 50.5 0.2 1.2e-12 48.0 0.2 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PRP89445.1 - 5.8e-11 42.7 0.3 2.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain adh_short_C2 PF13561.6 PRP89446.1 - 3.9e-53 180.4 0.2 5.1e-53 180.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PRP89446.1 - 2e-51 174.3 1.3 2.5e-51 173.9 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PRP89446.1 - 1.5e-11 44.5 0.5 2.2e-11 44.0 0.5 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PRP89446.1 - 6.7e-06 26.1 0.5 1e-05 25.5 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PRP89446.1 - 9.7e-06 25.2 0.1 2e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 PRP89446.1 - 0.0039 17.3 0.1 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 PRP89446.1 - 0.012 14.9 0.3 0.043 13.1 0.0 2.0 1 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 PRP89446.1 - 0.031 13.4 0.2 0.045 12.8 0.2 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 PRP89446.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1776 PF08643.10 PRP89446.1 - 0.069 12.5 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF1115 PF06544.12 PRP89447.1 - 0.003 17.7 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DGF-1_C PF11040.8 PRP89447.1 - 0.052 13.5 0.5 0.098 12.7 0.5 1.4 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF3563 PF12086.8 PRP89447.1 - 0.096 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Amidase PF01425.21 PRP89448.1 - 3.7e-141 471.2 0.0 4.6e-141 470.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Josephin PF02099.17 PRP89450.1 - 1.3e-18 67.6 2.0 2.6e-15 56.9 0.0 2.1 1 1 1 2 2 2 2 Josephin NmrA PF05368.13 PRP89451.1 - 4.1e-05 23.2 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Tugs PF17840.1 PRP89453.1 - 0.027 14.6 3.6 0.071 13.3 3.6 1.7 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain FtsH_ext PF06480.15 PRP89453.1 - 0.028 14.8 0.6 0.039 14.3 0.6 1.2 1 0 0 1 1 1 0 FtsH Extracellular Ras PF00071.22 PRP89454.1 - 6.8e-59 198.1 0.2 8.4e-59 197.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89454.1 - 3.9e-31 107.8 0.2 1e-30 106.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89454.1 - 9.3e-11 41.5 0.1 1.3e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP89454.1 - 9.9e-05 22.4 0.0 0.00019 21.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PRP89454.1 - 0.0035 17.3 0.2 0.42 10.5 0.0 2.3 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 PRP89454.1 - 0.0045 16.6 0.2 0.03 13.9 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PRP89454.1 - 0.041 13.2 0.0 0.056 12.8 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DAP3 PF10236.9 PRP89454.1 - 0.076 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 PRP89454.1 - 0.095 13.0 0.1 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PRP89454.1 - 0.13 12.2 0.2 0.8 9.7 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) C2 PF00168.30 PRP89455.1 - 6.3e-19 68.2 0.0 1.4e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain SMP_LBD PF17047.5 PRP89455.1 - 2.5e-05 23.8 0.4 4.1e-05 23.1 0.4 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MMM1 PF10296.9 PRP89455.1 - 0.078 12.0 2.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 Ras PF00071.22 PRP89456.1 - 6e-49 165.8 0.1 6.9e-49 165.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89456.1 - 2e-16 60.3 0.0 3.4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89456.1 - 2.2e-06 27.3 0.1 2.6e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP89456.1 - 0.0008 19.0 0.0 0.0017 17.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain His_Phos_2 PF00328.22 PRP89457.1 - 5.6e-27 95.1 0.1 7.1e-24 84.9 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aldo_ket_red PF00248.21 PRP89458.1 - 2.2e-57 194.5 0.0 1.6e-55 188.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Lipase_GDSL_2 PF13472.6 PRP89460.1 - 5.3e-05 23.7 1.6 7.6e-05 23.2 0.7 1.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PRP89460.1 - 0.0075 16.3 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 PRP89460.1 - 0.12 12.3 0.0 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate esterase 2 N-terminal Ureide_permease PF07168.11 PRP89461.1 - 4.9 5.8 5.6 0.4 9.4 0.5 1.6 2 0 0 2 2 2 0 Ureide permease CAP PF00188.26 PRP89462.1 - 9.1e-27 94.4 9.3 1.1e-26 94.1 9.3 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FeS_assembly_P PF01883.19 PRP89463.1 - 1.7e-05 24.9 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CotE PF10628.9 PRP89463.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) TFIID-31kDa PF02291.15 PRP89464.1 - 6.1e-34 116.7 0.1 7.6e-34 116.4 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 PRP89464.1 - 8.4e-10 38.5 0.0 8.6e-09 35.3 0.0 2.0 1 1 1 2 2 2 1 Bromodomain associated CENP-S PF15630.6 PRP89464.1 - 1.6e-05 25.2 0.0 2.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PRP89464.1 - 4e-05 23.7 0.1 5.9e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 PRP89464.1 - 0.012 16.0 1.5 0.038 14.3 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TAF PF02969.17 PRP89464.1 - 0.016 15.4 0.0 0.039 14.1 0.0 1.6 1 1 1 2 2 2 0 TATA box binding protein associated factor (TAF) LAMTOR5 PF16672.5 PRP89465.1 - 0.021 14.8 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 SUB1_ProdP9 PF18213.1 PRP89465.1 - 0.097 12.5 0.3 2.1 8.2 0.0 2.1 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 zinc_ribbon_16 PF17034.5 PRP89466.1 - 3.3e-21 75.8 15.2 9.2e-21 74.3 15.2 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 PRP89466.1 - 9.1e-07 29.5 6.6 1.1 10.3 0.0 6.1 4 1 1 5 5 5 2 WD domain, G-beta repeat Acetyltransf_CG PF14542.6 PRP89467.1 - 5.6e-13 48.8 0.0 7.1e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase START PF01852.19 PRP89468.1 - 0.00018 21.0 0.2 0.00063 19.2 0.1 1.8 2 0 0 2 2 2 1 START domain Tnp_22_trimer PF17489.2 PRP89470.1 - 5.5 7.0 7.9 4.3 7.4 1.1 2.5 1 1 1 2 2 2 0 L1 transposable element trimerization domain SET PF00856.28 PRP89471.1 - 4e-12 46.9 0.6 2.3e-08 34.6 0.1 3.2 2 1 0 2 2 2 1 SET domain Ank_2 PF12796.7 PRP89471.1 - 9.4e-07 29.3 0.0 2.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PRP89471.1 - 0.00032 20.9 0.0 0.24 12.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 PRP89471.1 - 0.0011 19.5 0.1 0.029 15.0 0.1 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP89471.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat PPL5 PF18168.1 PRP89471.1 - 0.0077 15.6 0.7 0.012 14.9 0.7 1.2 1 0 0 1 1 1 1 Prim-pol family 5 DDHD PF02862.17 PRP89471.1 - 0.021 15.0 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 DDHD domain DUF2518 PF10726.9 PRP89471.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of function (DUF2518) NECFESHC PF16621.5 PRP89471.1 - 0.15 12.0 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 Collagen PF01391.18 PRP89473.1 - 0.00094 18.9 7.8 0.00094 18.9 7.8 4.4 4 0 0 4 4 4 2 Collagen triple helix repeat (20 copies) PH PF00169.29 PRP89473.1 - 0.012 16.1 0.1 0.069 13.7 0.0 2.3 2 0 0 2 2 2 0 PH domain FLYWCH PF04500.16 PRP89474.1 - 0.049 13.7 0.6 0.11 12.7 0.6 1.6 1 0 0 1 1 1 0 FLYWCH zinc finger domain HTH_53 PF18606.1 PRP89475.1 - 0.049 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Band_7 PF01145.25 PRP89475.1 - 0.051 13.6 0.0 0.26 11.3 0.0 1.9 1 1 0 1 1 1 0 SPFH domain / Band 7 family MLTR_LBD PF17765.1 PRP89476.1 - 0.032 14.3 0.0 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain PAS PF00989.25 PRP89476.1 - 0.067 13.2 0.4 0.17 11.9 0.0 2.0 2 1 0 2 2 2 0 PAS fold Tom22 PF04281.13 PRP89476.1 - 1.2 8.9 7.0 3.1 7.6 5.6 2.3 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Sec7 PF01369.20 PRP89477.1 - 1.9e-48 164.6 0.5 5.5e-48 163.1 0.5 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PRP89477.1 - 2.6e-17 63.2 5.0 2.6e-17 63.2 5.0 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SARAF PF06682.12 PRP89478.1 - 1.1e-53 183.1 11.5 1.5e-51 176.0 11.5 2.6 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4385 PF14328.6 PRP89479.1 - 1.3e-60 203.7 10.0 2.5e-60 202.8 10.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4385) DUF2309 PF10070.9 PRP89479.1 - 0.027 12.8 0.6 0.032 12.6 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Peptidase_M13 PF01431.21 PRP89479.1 - 0.036 13.7 0.5 0.048 13.3 0.5 1.3 1 0 0 1 1 1 0 Peptidase family M13 DDE_3 PF13358.6 PRP89480.1 - 6.5e-13 48.7 0.0 1.9e-11 43.9 0.0 2.6 2 1 1 3 3 3 1 DDE superfamily endonuclease rve PF00665.26 PRP89480.1 - 0.0066 16.6 0.3 0.45 10.7 0.0 2.3 1 1 1 2 2 2 2 Integrase core domain TPP_enzyme_N PF02776.18 PRP89481.1 - 0.066 12.8 0.2 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain HECT PF00632.25 PRP89484.1 - 1.4e-51 175.8 1.5 2.4e-32 112.7 0.3 2.4 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) CPSF100_C PF13299.6 PRP89484.1 - 0.037 14.2 2.2 0.12 12.5 2.2 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Sec7_N PF12783.7 PRP89484.1 - 0.25 11.2 8.1 6 6.7 0.7 3.5 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Pox_Ag35 PF03286.14 PRP89484.1 - 0.35 10.6 4.8 0.87 9.3 4.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 PRP89484.1 - 0.35 8.9 10.6 0.89 7.6 10.6 1.6 1 0 0 1 1 1 0 DNA polymerase phi DUF5523 PF17661.1 PRP89484.1 - 0.37 10.4 13.1 0.69 9.6 9.5 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5523) RhoGAP PF00620.27 PRP89485.1 - 3e-22 79.1 0.4 1.8e-21 76.6 0.0 2.6 3 0 0 3 3 3 1 RhoGAP domain CH PF00307.31 PRP89485.1 - 2.2e-09 37.5 0.0 0.00026 21.2 0.0 3.0 1 1 1 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PRP89485.1 - 0.00059 19.6 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain ATG16 PF08614.11 PRP89485.1 - 0.053 13.7 33.9 0.79 9.9 9.3 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 PRP89485.1 - 1 9.5 24.7 3.1 8.0 13.3 3.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 PRP89485.1 - 1.4 8.9 33.5 0.77 9.8 15.6 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 PRP89485.1 - 1.9 8.6 11.9 9.2 6.4 8.0 3.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF489 PF04356.12 PRP89485.1 - 2 8.4 15.7 0.87 9.6 5.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF489) HAP1_N PF04849.13 PRP89485.1 - 2 7.5 26.9 0.1 11.8 10.0 2.2 2 0 0 2 2 2 0 HAP1 N-terminal conserved region APG6_N PF17675.1 PRP89485.1 - 2.2 8.8 31.1 19 5.8 15.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 PRP89485.1 - 2.4 8.6 28.4 0.5 10.8 8.7 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) OmpH PF03938.14 PRP89485.1 - 7 7.0 34.8 0.37 11.1 13.5 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 PRP89485.1 - 7.7 5.5 28.0 0.55 9.3 9.7 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 PRP89485.1 - 9.7 5.9 33.8 0.04 13.7 14.8 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PIP5K PF01504.18 PRP89486.1 - 1.8e-63 214.4 0.7 5.6e-63 212.7 0.7 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase peroxidase PF00141.23 PRP89486.1 - 5.5e-45 153.8 0.0 1.1e-44 152.8 0.0 1.6 1 0 0 1 1 1 1 Peroxidase 7tm_1 PF00001.21 PRP89486.1 - 1.8e-06 27.5 2.8 3.1e-06 26.7 2.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 PRP89486.1 - 0.00014 21.1 2.2 0.00014 21.1 2.2 2.3 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Arm PF00514.23 PRP89486.1 - 0.00024 21.0 2.8 0.2 11.7 0.0 4.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 PRP89486.1 - 0.00092 17.9 6.3 0.23 10.0 2.9 2.5 1 1 0 2 2 2 2 Adaptin N terminal region Frizzled PF01534.17 PRP89486.1 - 0.0035 16.4 8.1 0.044 12.8 8.4 2.5 2 1 0 2 2 2 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 PRP89486.1 - 0.0059 15.9 3.6 0.014 14.7 3.6 1.6 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Usp PF00582.26 PRP89488.1 - 7.3e-22 78.4 0.1 1e-21 77.9 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family DAGK_cat PF00781.24 PRP89488.1 - 0.01 15.4 0.1 0.019 14.6 0.1 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MCM_lid PF17855.1 PRP89489.1 - 2.2e-07 31.2 0.0 5.3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM PF00493.23 PRP89489.1 - 3.7e-07 29.5 0.0 9.6e-07 28.1 0.0 1.6 1 1 0 1 1 1 1 MCM P-loop domain Glyco_hydro_18 PF00704.28 PRP89490.1 - 1.8e-16 60.7 0.3 2.7e-16 60.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 PRP89490.1 - 8.6e-07 29.3 8.1 1.8e-06 28.3 8.1 1.5 1 0 0 1 1 1 1 Chitin recognition protein PT PF04886.12 PRP89490.1 - 1.4e-05 24.5 18.9 0.0022 17.5 18.9 2.6 1 1 0 1 1 1 1 PT repeat Glycoprotein_G PF00802.19 PRP89490.1 - 0.048 13.0 2.8 0.069 12.5 2.8 1.3 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G DUF4106 PF13388.6 PRP89490.1 - 2.9 7.1 5.7 4.6 6.4 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RasGEF PF00617.19 PRP89491.1 - 2.4e-44 151.6 1.0 2.4e-44 151.6 1.0 3.5 3 1 0 3 3 3 2 RasGEF domain TruB_C_2 PF16198.5 PRP89491.1 - 0.036 14.2 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Peptidase_C1 PF00112.23 PRP89492.1 - 5e-51 173.9 1.0 1.6e-50 172.2 1.0 1.9 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 PRP89492.1 - 7.1e-15 56.0 0.8 7.1e-15 56.0 0.8 2.7 2 1 0 2 2 2 1 Cysteine-rich secretory protein family WSC PF01822.19 PRP89492.1 - 2e-11 43.9 32.4 3.9e-11 43.0 12.5 3.8 4 0 0 4 4 4 2 WSC domain Peptidase_C1_2 PF03051.15 PRP89492.1 - 0.00031 19.7 1.9 0.029 13.1 0.6 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Vitellogenin_N PF01347.22 PRP89493.1 - 0.05 12.0 0.1 0.06 11.7 0.1 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region Ank_3 PF13606.6 PRP89495.1 - 2e-06 27.7 2.0 0.04 14.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 PRP89495.1 - 0.00026 21.5 0.0 0.00043 20.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP89495.1 - 0.038 14.6 0.0 0.37 11.4 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) RNase_P_p30 PF01876.16 PRP89495.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit p30 DUF974 PF06159.13 PRP89496.1 - 3e-66 223.7 0.1 4.1e-66 223.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Transglut_C PF00927.22 PRP89496.1 - 7.7e-05 22.8 1.7 0.047 13.8 0.0 4.3 4 1 1 5 5 5 1 Transglutaminase family, C-terminal ig like domain DUF5300 PF17224.3 PRP89496.1 - 0.053 13.8 0.2 0.17 12.2 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5300) AMPK1_CBM PF16561.5 PRP89497.1 - 8.8e-13 48.3 0.3 3.2e-12 46.5 0.3 2.1 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Rieske PF00355.26 PRP89497.1 - 1.7e-07 31.1 0.0 4.7e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PRP89497.1 - 5.5e-06 26.3 0.0 1.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Asp4 PF16996.5 PRP89497.1 - 0.021 14.6 2.1 0.12 12.1 0.0 3.7 2 0 0 2 2 2 0 Accessory secretory protein Sec Asp4 PhoD_N PF16655.5 PRP89497.1 - 0.064 13.8 0.0 0.79 10.3 0.0 3.0 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain DUF357 PF04010.13 PRP89497.1 - 0.089 12.9 0.4 0.9 9.7 0.4 2.9 1 0 0 1 1 1 0 Protein of unknown function (DUF357) fn3 PF00041.21 PRP89497.1 - 0.16 12.3 1.0 4.3 7.8 0.0 4.0 4 0 0 4 4 4 0 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PRP89497.1 - 0.7 10.5 0.0 0.7 10.5 0.0 4.5 4 1 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Shugoshin_N PF07558.11 PRP89497.1 - 3.5 7.6 63.1 1.5 8.8 0.3 11.6 12 0 0 12 12 12 0 Shugoshin N-terminal coiled-coil region PfUIS3 PF11567.8 PRP89497.1 - 4.3 7.8 38.7 0.51 10.7 0.6 8.0 6 1 0 6 6 6 0 Plasmodium falciparum UIS3 membrane protein CH PF00307.31 PRP89498.1 - 6.3e-06 26.3 0.0 3.8e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Calponin homology (CH) domain DUF2897 PF11446.8 PRP89498.1 - 0.05 13.5 5.4 0.11 12.4 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) VWA_2 PF13519.6 PRP89499.1 - 2.1e-21 76.6 0.3 1.6e-20 73.7 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 PRP89499.1 - 1.3e-10 41.4 0.1 2.6e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 PRP89499.1 - 4.2e-05 23.2 28.1 0.011 15.6 2.7 3.9 4 0 0 4 4 4 3 Ubiquitin interaction motif RAP80_UIM PF18282.1 PRP89499.1 - 0.028 14.2 7.5 5.5 6.8 0.1 3.9 4 0 0 4 4 4 0 RAP80 N-terminal ubiquitin interaction motif GET2 PF08690.10 PRP89499.1 - 0.95 9.1 7.7 0.44 10.2 5.2 1.6 1 1 0 1 1 1 0 GET complex subunit GET2 MAPKK1_Int PF08923.10 PRP89500.1 - 1.4e-28 99.1 0.0 1.6e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Robl_LC7 PF03259.17 PRP89500.1 - 0.028 14.2 0.1 0.038 13.8 0.1 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain MCM PF00493.23 PRP89501.1 - 1.5e-58 197.5 0.3 7.5e-52 175.6 0.0 2.4 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 PRP89501.1 - 4.1e-22 78.4 0.2 1.3e-21 76.8 0.2 1.8 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PRP89501.1 - 5.4e-17 62.0 1.5 1.1e-16 61.0 1.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PRP89501.1 - 6.6e-08 32.2 0.2 0.00072 19.0 0.0 2.8 1 1 2 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PRP89501.1 - 3.2e-07 30.4 0.0 7.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PRP89501.1 - 0.026 14.9 0.5 0.14 12.6 0.2 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 PRP89501.1 - 0.035 14.4 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 PRP89501.1 - 0.099 12.0 0.0 0.3 10.4 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family Tim44 PF04280.15 PRP89501.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Tim44-like domain Pkinase PF00069.25 PRP89502.1 - 2e-61 207.7 0.0 2.8e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89502.1 - 1.3e-44 152.4 0.0 6.2e-44 150.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP89502.1 - 2.3e-06 26.7 0.3 6.5e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PRP89502.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3042 PF11240.8 PRP89502.1 - 0.064 13.3 0.2 0.18 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) TMEM223 PF14640.6 PRP89504.1 - 0.031 14.5 0.0 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 Carb_bind PF10645.9 PRP89504.1 - 0.2 11.9 4.3 0.34 11.1 4.3 1.4 1 0 0 1 1 1 0 Carbohydrate binding ABC_membrane PF00664.23 PRP89506.1 - 8.6e-62 209.3 18.1 1.1e-61 208.9 18.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PRP89506.1 - 2.6e-32 112.2 0.0 5.3e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PRP89506.1 - 1.1e-07 31.5 0.1 4.3e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PRP89506.1 - 0.0022 17.7 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 PRP89506.1 - 0.0087 16.3 0.1 0.44 10.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PRP89506.1 - 0.011 16.1 0.4 0.058 13.8 0.4 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 PRP89506.1 - 0.018 15.4 0.0 5.5 7.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PRP89506.1 - 0.022 14.7 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 PRP89506.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 PRP89506.1 - 0.041 13.9 0.1 3.1 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 PRP89506.1 - 0.15 11.9 0.0 21 5.0 0.0 2.6 2 0 0 2 2 2 0 NTPase T_hemolysin PF12261.8 PRP89506.1 - 0.19 11.5 0.3 8.1 6.2 0.0 2.6 3 0 0 3 3 3 0 Thermostable hemolysin zf-Tim10_DDP PF02953.15 PRP89507.1 - 1e-14 53.9 1.0 1.6e-14 53.2 1.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PHD PF00628.29 PRP89508.1 - 0.00067 19.5 13.8 0.00067 19.5 13.8 3.7 3 0 0 3 3 3 1 PHD-finger Ras PF00071.22 PRP89509.1 - 3.3e-08 33.3 0.0 9.8e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89509.1 - 0.0056 16.9 0.0 0.026 14.7 0.0 2.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase zf-RING_2 PF13639.6 PRP89511.1 - 1.5e-12 47.7 12.2 2.3e-12 47.0 12.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PRP89511.1 - 6.1e-08 32.8 13.1 1.2e-07 31.9 13.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PRP89511.1 - 1.1e-07 31.4 3.0 2.3e-07 30.4 3.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PRP89511.1 - 2.2e-07 30.6 12.2 3.8e-07 29.8 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PRP89511.1 - 3.3e-06 26.8 12.5 6e-06 26.0 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PRP89511.1 - 2.3e-05 24.3 7.9 4.3e-05 23.4 7.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PRP89511.1 - 9.4e-05 22.2 11.3 0.00015 21.6 11.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PRP89511.1 - 0.00034 20.5 11.0 0.00057 19.8 11.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PRP89511.1 - 0.00045 20.2 7.3 0.0012 18.8 7.2 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PRP89511.1 - 0.0036 17.1 8.4 0.0068 16.2 8.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Peptidase_C33 PF05412.12 PRP89511.1 - 0.082 12.9 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase Tmpp129 PF10272.9 PRP89511.1 - 0.29 10.4 5.9 0.08 12.2 3.3 1.4 1 1 0 1 1 1 0 Putative transmembrane protein precursor Zn_ribbon_17 PF17120.5 PRP89511.1 - 0.52 10.0 12.3 0.88 9.2 12.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Slp PF03843.13 PRP89512.1 - 0.17 11.3 0.3 15 4.9 0.2 2.7 2 1 1 3 3 3 0 Outer membrane lipoprotein Slp family CDC48_2 PF02933.17 PRP89512.1 - 2.1 8.2 6.8 0.1 12.4 0.9 1.8 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 EloA-BP1 PF15870.5 PRP89513.1 - 4.8e-10 39.9 13.4 1.5e-08 35.0 0.0 4.8 5 0 0 5 5 5 2 ElonginA binding-protein 1 TFIIS_M PF07500.14 PRP89513.1 - 0.036 14.5 1.4 0.41 11.1 0.4 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain KIX_2 PF16987.5 PRP89513.1 - 6.3 6.9 8.5 6.1 6.9 0.1 2.9 3 0 0 3 3 3 0 KIX domain Nucleoside_tran PF01733.18 PRP89514.1 - 7.6e-49 166.7 5.9 1.4e-48 165.8 5.9 1.4 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 PRP89514.1 - 0.00028 19.9 39.5 0.0042 16.1 11.0 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.8 PRP89514.1 - 3.6 7.7 10.1 0.45 10.6 3.0 2.9 3 0 0 3 3 3 0 Protein of unknown function adh_short PF00106.25 PRP89515.1 - 9.8e-16 57.8 0.0 3.8e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 PRP89515.1 - 1.4e-08 34.8 0.0 1.9e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 PRP89515.1 - 9.2e-07 28.7 0.0 1.3e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PRP89515.1 - 0.00019 21.0 0.1 0.00057 19.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP89515.1 - 0.013 14.9 0.0 0.34 10.3 0.0 2.2 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase TPALS PF18178.1 PRP89515.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family Glyco_hydro_47 PF01532.20 PRP89516.1 - 6.4e-109 364.9 0.0 1.2e-108 364.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 PRP89516.1 - 3.4e-09 36.6 0.0 6.6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Lipase_GDSL_2 PF13472.6 PRP89517.1 - 1.9e-24 87.0 0.0 2.3e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PRP89517.1 - 1e-10 42.0 0.0 1.5e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aldo_ket_red PF00248.21 PRP89518.1 - 1.7e-40 139.1 0.0 3.2e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 PRP89518.1 - 3.5e-33 114.8 0.0 8.5e-33 113.6 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 PRP89518.1 - 1.4e-24 86.7 0.0 2.5e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 PRP89518.1 - 3.1e-10 40.2 0.0 8e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 PRP89518.1 - 0.00011 21.7 0.0 0.0014 18.2 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PRP89518.1 - 0.014 14.8 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 PRP89520.1 - 6.3e-44 150.3 0.1 6.9e-22 78.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89520.1 - 5.7e-13 48.7 0.2 5.8e-07 29.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase VPS9 PF02204.18 PRP89520.1 - 8.3e-13 48.5 0.2 2.3e-12 47.0 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RasGAP PF00616.19 PRP89520.1 - 0.00017 21.3 0.0 0.00017 21.3 0.0 3.3 4 0 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase Pkinase_fungal PF17667.1 PRP89520.1 - 0.016 14.0 0.0 0.016 14.0 0.0 2.8 3 0 0 3 3 3 0 Fungal protein kinase DUF4639 PF15479.6 PRP89520.1 - 0.74 8.7 6.8 1.4 7.8 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Tweety PF04906.13 PRP89522.1 - 0.00013 20.8 1.8 0.00013 20.8 1.8 2.5 2 1 1 3 3 3 2 Tweety PfkB PF00294.24 PRP89523.1 - 2.6e-15 56.5 0.0 3.6e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 PRP89523.1 - 0.00031 20.2 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF962 PF06127.11 PRP89524.1 - 7.9e-33 112.4 0.2 8.8e-33 112.3 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Carb_bind PF10645.9 PRP89525.1 - 7.8e-12 45.2 60.7 0.011 15.9 5.3 7.1 6 0 0 6 6 6 5 Carbohydrate binding Thaumatin PF00314.17 PRP89525.1 - 1.6e-07 31.2 4.8 1.6e-07 31.2 4.8 7.0 2 2 1 5 5 5 1 Thaumatin family PAN_4 PF14295.6 PRP89525.1 - 0.0002 21.2 3.2 0.0002 21.2 3.2 3.4 3 0 0 3 3 3 1 PAN domain SWIM PF04434.17 PRP89526.1 - 1.2e-07 31.3 0.2 3.2e-07 29.9 0.2 1.8 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.6 PRP89526.1 - 3.5e-05 24.0 7.2 3.5e-05 24.0 7.2 2.6 3 1 0 3 3 1 1 Ring finger domain zf-C2H2 PF00096.26 PRP89526.1 - 0.00013 22.2 0.3 0.00013 22.2 0.3 3.1 3 0 0 3 3 2 1 Zinc finger, C2H2 type zf-RING_UBOX PF13445.6 PRP89526.1 - 0.001 19.0 1.9 0.005 16.8 1.9 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C2H2_4 PF13894.6 PRP89526.1 - 0.0011 19.6 0.2 0.0011 19.6 0.2 3.3 4 0 0 4 4 3 1 C2H2-type zinc finger DUF4764 PF15961.5 PRP89526.1 - 0.004 15.9 0.0 0.0067 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4764) zf-ANAPC11 PF12861.7 PRP89526.1 - 0.0084 16.1 3.3 0.0084 16.1 3.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf_C2H2_ZHX PF18387.1 PRP89526.1 - 0.023 14.3 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 PRP89526.1 - 0.093 12.8 2.8 0.28 11.2 0.2 3.0 3 0 0 3 3 3 0 BED zinc finger zf-C3HC4_4 PF15227.6 PRP89526.1 - 0.12 12.5 7.0 0.078 13.2 3.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PRP89526.1 - 0.22 11.4 7.4 0.2 11.5 4.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 PRP89526.1 - 0.59 10.4 10.9 0.11 12.6 7.2 1.8 2 0 0 2 2 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 PRP89526.1 - 1.1 9.1 8.1 1.9 8.4 6.2 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 PRP89526.1 - 1.8 8.5 14.6 0.25 11.3 9.5 2.3 2 0 0 2 2 2 0 PHD-finger zf-RING_4 PF14570.6 PRP89526.1 - 1.8 8.4 13.2 0.1 12.4 7.3 2.1 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain C1_1 PF00130.22 PRP89526.1 - 3.3 7.7 12.4 0.12 12.3 3.1 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 PRP89526.1 - 4.8 7.4 11.7 11 6.2 11.7 1.7 1 0 0 1 1 1 0 RING-variant domain zf-Di19 PF05605.12 PRP89526.1 - 5.4 7.4 7.3 21 5.5 0.0 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-rbx1 PF12678.7 PRP89526.1 - 6.4 7.1 10.5 9.1 6.7 8.8 2.3 2 1 0 2 2 1 0 RING-H2 zinc finger domain SCRL PF06876.12 PRP89526.1 - 9 6.6 13.3 1.2 9.4 5.3 2.6 2 1 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein WD40 PF00400.32 PRP89527.1 - 5.1e-27 93.6 18.9 0.0095 16.8 0.0 12.4 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP89527.1 - 1.6e-09 38.0 0.2 2 8.8 0.0 7.0 5 3 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 PRP89527.1 - 2.1e-05 24.9 0.1 0.00012 22.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 PRP89527.1 - 3.7e-05 23.0 0.1 0.00032 20.0 0.2 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PRP89527.1 - 0.00027 20.6 1.5 0.0077 16.1 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain Nup160 PF11715.8 PRP89527.1 - 0.0032 16.2 0.1 1.7 7.2 0.1 3.0 3 0 0 3 3 3 2 Nucleoporin Nup120/160 EF-hand_5 PF13202.6 PRP89527.1 - 0.033 13.7 0.2 0.094 12.2 0.2 1.8 1 0 0 1 1 1 0 EF hand MORN PF02493.20 PRP89528.1 - 4.5e-23 79.7 19.2 4.9e-06 26.1 0.2 5.5 5 0 0 5 5 5 5 MORN repeat Ribosomal_S7e PF01251.18 PRP89530.1 - 3.3e-75 251.9 3.4 4e-75 251.6 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Amino_oxidase PF01593.24 PRP89531.1 - 9.2e-84 282.3 0.0 1.3e-82 278.5 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PRP89531.1 - 6.5e-14 51.9 0.3 1.4e-13 50.8 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SWIRM PF04433.17 PRP89531.1 - 1.5e-09 38.1 0.2 2.5e-08 34.2 0.0 2.4 1 1 1 2 2 2 1 SWIRM domain Pyr_redox_2 PF07992.14 PRP89531.1 - 1.5e-08 34.2 0.1 4.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rubrerythrin PF02915.17 PRP89531.1 - 1.1e-06 29.1 0.0 3.5e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Rubrerythrin FAD_oxidored PF12831.7 PRP89531.1 - 1.1e-06 28.2 3.9 7e-05 22.4 2.3 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PRP89531.1 - 1.5e-06 27.5 0.5 3.5e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 PRP89531.1 - 6.8e-05 23.3 2.1 0.00015 22.3 0.3 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP89531.1 - 0.00015 21.5 0.3 0.00042 20.0 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PRP89531.1 - 0.00023 20.5 0.1 0.12 11.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP89531.1 - 0.00026 19.8 1.4 0.0054 15.5 0.5 2.8 3 0 0 3 3 3 1 HI0933-like protein IlvN PF07991.12 PRP89531.1 - 0.00041 20.0 0.2 0.00096 18.8 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 PRP89531.1 - 0.0011 18.3 0.4 0.0023 17.3 0.4 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 PRP89531.1 - 0.0019 17.4 0.4 0.0019 17.4 0.4 2.3 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PRP89531.1 - 0.0032 16.8 1.0 0.056 12.7 0.2 2.8 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.12 PRP89531.1 - 0.008 15.3 1.4 0.0087 15.2 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 PRP89531.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family RapA_C PF12137.8 PRP89531.1 - 0.14 11.2 0.1 0.3 10.1 0.1 1.5 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal ThiF PF00899.21 PRP89531.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family 2-Hacid_dh_C PF02826.19 PRP89531.1 - 0.15 11.4 0.0 0.42 10.0 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 PRP89531.1 - 0.39 10.7 2.1 1.7 8.6 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding zf-CCCH_4 PF18044.1 PRP89532.1 - 9.9e-05 22.1 1.7 0.00014 21.5 1.7 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PRP89532.1 - 0.00094 19.2 4.5 0.0014 18.6 4.5 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PRP89532.1 - 0.02 14.8 1.4 0.034 14.1 1.4 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 PRP89532.1 - 0.15 12.8 0.1 0.15 12.8 0.1 2.7 3 0 0 3 3 3 0 Torus domain PhoQ_Sensor PF08918.10 PRP89532.1 - 0.41 10.5 1.4 0.62 9.9 0.3 1.9 1 1 1 2 2 2 0 PhoQ Sensor Pyr_redox_2 PF07992.14 PRP89533.1 - 1.6e-25 89.9 0.0 8.8e-25 87.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PRP89533.1 - 1.7e-05 23.9 0.1 0.12 11.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 PRP89533.1 - 0.00011 22.7 2.1 0.12 13.0 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PRP89533.1 - 0.00039 20.1 0.3 0.0032 17.1 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PRP89533.1 - 0.041 13.1 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GATA PF00320.27 PRP89534.1 - 6.1e-06 25.7 3.0 1.4e-05 24.6 3.0 1.6 1 0 0 1 1 1 1 GATA zinc finger FtsJ PF01728.19 PRP89535.1 - 2.5e-27 96.1 0.0 5.1e-27 95.1 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Lipase_3 PF01764.25 PRP89536.1 - 6.6e-35 120.1 0.0 1.1e-34 119.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 PRP89536.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PRP89536.1 - 0.0045 17.6 0.2 0.0086 16.7 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 PRP89536.1 - 0.021 14.8 0.0 0.055 13.4 0.0 1.7 1 1 0 1 1 1 0 Cutinase PGAP1 PF07819.13 PRP89536.1 - 0.021 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 PRP89536.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 PRP89536.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 PRP89536.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) ATP-synt PF00231.19 PRP89537.1 - 1.9e-78 264.0 1.7 2.4e-78 263.7 1.7 1.1 1 0 0 1 1 1 1 ATP synthase DUF2808 PF10989.8 PRP89537.1 - 0.14 12.1 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) Kelch_1 PF01344.25 PRP89538.1 - 2.5e-41 139.0 13.2 2.5e-10 39.8 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 PRP89538.1 - 1.2e-36 124.3 15.1 2.5e-09 37.2 0.1 6.5 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 PRP89538.1 - 1.7e-35 120.4 9.1 1.3e-10 41.0 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PRP89538.1 - 6.4e-35 118.3 15.9 2.6e-07 30.7 0.0 6.2 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 PRP89538.1 - 2.2e-31 106.6 14.1 5.3e-06 26.2 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 PRP89538.1 - 4.2e-25 87.5 12.3 2.4e-07 30.7 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain F-box-like PF12937.7 PRP89538.1 - 1.8e-07 31.0 0.0 4.1e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP89538.1 - 0.0003 20.6 0.0 0.00061 19.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain RAG2 PF03089.14 PRP89538.1 - 0.045 12.7 0.4 0.66 8.9 0.2 2.5 3 0 0 3 3 3 0 Recombination activating protein 2 TLD PF07534.16 PRP89538.1 - 0.068 13.4 0.0 23 5.2 0.0 3.1 3 0 0 3 3 3 0 TLD Grg1 PF11034.8 PRP89539.1 - 0.012 15.8 0.2 0.019 15.2 0.2 1.4 1 0 0 1 1 1 0 Glucose-repressible protein Grg1 Pkinase PF00069.25 PRP89540.1 - 1.2e-41 142.9 0.2 2.9e-25 89.1 0.2 3.5 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89540.1 - 4.9e-31 107.9 0.8 2.7e-23 82.6 0.3 3.3 2 1 0 2 2 2 2 Protein tyrosine kinase GPS PF01825.21 PRP89540.1 - 1.4e-08 35.1 3.9 1.4e-08 35.1 3.9 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif GIT_CC PF16559.5 PRP89540.1 - 2.1 8.3 8.6 0.5 10.3 4.1 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Syja_N PF02383.18 PRP89541.1 - 8.1e-85 284.9 0.3 1.3e-84 284.2 0.3 1.4 1 0 0 1 1 1 1 SacI homology domain DDE_Tnp_1 PF01609.21 PRP89541.1 - 0.05 13.2 0.0 7.8 6.1 0.0 2.9 3 0 0 3 3 3 0 Transposase DDE domain COX14 PF14880.6 PRP89542.1 - 0.00052 19.8 1.8 0.0011 18.7 1.8 1.6 1 1 0 1 1 1 1 Cytochrome oxidase c assembly Pkinase PF00069.25 PRP89547.1 - 3.7e-47 160.9 0.0 4.2e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89547.1 - 4e-20 72.2 0.0 5.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP89547.1 - 2.3e-08 33.7 0.0 4.4e-08 32.8 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PRP89547.1 - 5.5e-05 23.2 0.1 0.0075 16.2 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PRP89547.1 - 0.0014 18.0 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.25 PRP89548.1 - 1.2e-15 57.8 0.0 2.8e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.9 PRP89548.1 - 0.0087 16.4 3.2 0.02 15.3 3.2 1.7 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III IZUMO PF15005.6 PRP89548.1 - 0.022 15.3 0.3 0.049 14.1 0.3 1.6 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF4303 PF14136.6 PRP89548.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) DNAJ_related PF12339.8 PRP89548.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA-J related protein OmpH PF03938.14 PRP89549.1 - 7 7.0 7.8 2.2 8.6 4.4 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) VPS9 PF02204.18 PRP89550.1 - 5.9e-17 61.8 0.1 1.4e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SH3BGR PF04908.15 PRP89551.1 - 1.2e-09 38.2 0.9 1.9e-09 37.6 0.9 1.3 1 1 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 PRP89551.1 - 9.6e-05 22.5 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GDA1_CD39 PF01150.17 PRP89552.1 - 1.1e-71 241.8 0.0 1.6e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Aminotran_1_2 PF00155.21 PRP89553.1 - 9.3e-43 146.8 0.0 1.3e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SMG1 PF15785.5 PRP89553.1 - 0.078 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Stealth_CR2 PF11380.8 PRP89554.1 - 7.6e-19 67.9 0.3 2e-18 66.5 0.3 1.7 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 PRP89554.1 - 3.8e-09 36.1 0.2 8.6e-09 35.0 0.2 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 PRP89554.1 - 0.018 14.9 0.1 0.018 14.9 0.1 1.8 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 PRP89554.1 - 2.2 8.3 5.8 3.2 7.7 4.3 2.1 2 0 0 2 2 2 0 Stealth protein CR3, conserved region 3 Arrestin_N PF00339.29 PRP89555.1 - 3.2e-26 92.2 0.8 3.6e-23 82.2 0.1 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 PRP89555.1 - 4.8e-09 36.8 1.4 9.1e-08 32.6 0.3 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 PRP89555.1 - 0.0031 17.1 0.0 0.14 11.6 0.0 2.4 3 0 0 3 3 3 1 SpoOM protein LDB19 PF13002.7 PRP89555.1 - 0.025 14.3 0.1 0.064 13.0 0.0 1.7 2 0 0 2 2 2 0 Arrestin_N terminal like Rgp1 PF08737.10 PRP89555.1 - 0.041 13.1 1.4 0.15 11.2 1.3 1.7 1 1 0 1 1 1 0 Rgp1 DUF1682 PF07946.14 PRP89556.1 - 1.9 7.6 24.0 0.22 10.7 13.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Pkinase_Tyr PF07714.17 PRP89557.1 - 1.4e-141 470.3 0.0 8.4e-71 238.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP89557.1 - 1.9e-94 315.9 0.0 9.2e-48 162.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 PRP89557.1 - 1.4e-77 255.4 159.4 4.5e-08 32.7 4.8 23.3 16 8 9 27 27 27 19 Leucine rich repeat Cellulase PF00150.18 PRP89557.1 - 2.5e-41 142.0 24.9 3.8e-23 82.3 0.9 4.2 4 0 0 4 4 4 4 Cellulase (glycosyl hydrolase family 5) LRR_4 PF12799.7 PRP89557.1 - 1.1e-38 130.5 195.7 5.8e-05 23.4 2.6 31.4 15 9 19 38 38 38 22 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 PRP89557.1 - 2.4e-12 46.8 0.0 7.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like LRR_1 PF00560.33 PRP89557.1 - 4.5e-08 32.6 109.3 0.44 11.3 0.2 32.2 32 7 0 32 32 29 4 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP89557.1 - 4.7e-06 25.6 0.0 0.08 11.7 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Kdo PF06293.14 PRP89557.1 - 0.00016 21.1 0.1 0.51 9.6 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_5 PF13306.6 PRP89557.1 - 0.00086 19.3 11.2 1.5 8.8 0.0 7.2 8 1 0 8 8 8 2 BspA type Leucine rich repeat region (6 copies) Mucin15 PF15672.5 PRP89557.1 - 0.0051 16.3 0.1 0.014 14.9 0.1 1.7 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 Adeno_E3_CR2 PF02439.15 PRP89557.1 - 0.067 13.0 3.9 0.78 9.5 0.4 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Phage_holin_3_6 PF07332.11 PRP89557.1 - 0.12 12.4 1.1 11 6.1 0.1 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Syndecan PF01034.20 PRP89557.1 - 1.4 8.9 6.9 7.4 6.6 0.4 2.5 2 0 0 2 2 2 0 Syndecan domain Insulin_TMD PF17870.1 PRP89557.1 - 3.1 7.9 11.1 7.1 6.8 0.2 3.7 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment EphA2_TM PF14575.6 PRP89557.1 - 3.8 8.4 7.8 5.7 7.9 0.1 3.0 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain Sugar_tr PF00083.24 PRP89558.1 - 6e-117 391.3 25.0 7.3e-117 391.0 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PRP89558.1 - 2.1e-26 92.7 28.6 2.6e-18 66.1 5.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2929 PF11151.8 PRP89558.1 - 0.054 13.8 7.9 0.056 13.7 4.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) OTCace PF00185.24 PRP89560.1 - 0.00017 21.7 0.2 0.00028 21.0 0.2 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LAP1C PF05609.12 PRP89560.1 - 0.21 10.6 6.3 0.22 10.5 6.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2058 PF09831.9 PRP89560.1 - 0.38 10.9 9.3 0.65 10.1 9.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Zip PF02535.22 PRP89560.1 - 1.1 8.4 4.1 1 8.5 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 PRP89560.1 - 1.3 7.7 4.5 1.4 7.6 4.5 1.1 1 0 0 1 1 1 0 Presenilin CCDC71L PF15374.6 PRP89560.1 - 1.4 8.1 8.5 1.7 7.8 8.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF4820 PF16091.5 PRP89560.1 - 7 5.9 9.6 11 5.3 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Pkinase_Tyr PF07714.17 PRP89561.1 - 7.6e-64 215.5 0.0 1.1e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP89561.1 - 7e-52 173.0 108.4 1.6e-08 34.2 5.5 15.9 10 5 8 19 19 19 16 Leucine rich repeat Pkinase PF00069.25 PRP89561.1 - 5.9e-45 153.7 0.0 9.1e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP89561.1 - 6.7e-39 131.3 123.8 0.00017 21.9 2.1 19.8 15 5 4 20 20 20 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PRP89561.1 - 2.6e-08 33.3 97.8 1.4 9.8 0.1 26.6 30 3 0 30 30 30 3 Leucine Rich Repeat LRR_6 PF13516.6 PRP89561.1 - 4.7e-08 32.5 87.1 1.1 9.5 0.1 23.0 26 0 0 26 26 26 5 Leucine Rich repeat PTP_tm PF18861.1 PRP89561.1 - 0.00093 19.2 0.1 0.0022 18.0 0.1 1.6 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Kdo PF06293.14 PRP89561.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP89561.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PRP89561.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RhoGAP PF00620.27 PRP89562.1 - 2.4e-39 134.6 0.1 3.9e-39 133.9 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 PRP89562.1 - 0.0011 19.5 0.1 0.0019 18.7 0.1 1.4 1 0 0 1 1 1 1 PH domain TRAP_beta PF05753.14 PRP89563.1 - 8.5e-30 103.5 0.3 1.2e-29 102.9 0.3 1.2 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) Insulin_TMD PF17870.1 PRP89563.1 - 0.095 12.8 4.1 1.5 9.0 1.2 2.3 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF4395 PF14340.6 PRP89564.1 - 2.2e-23 83.0 11.8 2.2e-23 83.0 11.8 3.1 4 1 0 4 4 4 1 Domain of unknown function (DUF4395) TMEM173 PF15009.6 PRP89564.1 - 1.6 7.8 7.2 0.12 11.5 0.9 2.2 2 0 0 2 2 2 0 Transmembrane protein 173 GPR_Gpa2_C PF11970.8 PRP89564.1 - 2.3 8.3 8.2 2.4 8.3 3.7 2.9 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Kinesin_assoc PF16183.5 PRP89566.1 - 0.04 14.1 1.5 6 7.0 0.1 2.2 2 0 0 2 2 2 0 Kinesin-associated EDS1_EP PF18117.1 PRP89566.1 - 0.046 14.2 0.6 12 6.4 0.1 2.2 2 0 0 2 2 2 0 Enhanced disease susceptibility 1 protein EP domain LZ3wCH PF18517.1 PRP89566.1 - 0.07 13.2 0.1 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Leucine zipper with capping helix domain DASH_Dam1 PF08653.10 PRP89566.1 - 0.092 12.6 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 AOX PF01786.17 PRP89567.1 - 7.3e-86 287.2 0.4 9e-86 286.9 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase Ribosomal_S15 PF00312.22 PRP89567.1 - 0.12 12.7 0.3 6.8 7.0 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S15 CTP_transf_like PF01467.26 PRP89568.1 - 4.1e-13 49.7 0.1 4.9e-13 49.5 0.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 PRP89568.1 - 0.005 16.7 0.2 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 FAD synthetase ATP-sulfurylase PF01747.17 PRP89568.1 - 0.14 11.6 0.6 0.7 9.3 0.0 2.1 2 0 0 2 2 2 0 ATP-sulfurylase Alpha-amylase PF00128.24 PRP89569.1 - 9.3e-11 41.9 0.0 2.2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain PNRC PF15365.6 PRP89570.1 - 0.11 12.4 1.7 0.19 11.6 1.7 1.4 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Sdh_cyt PF01127.22 PRP89571.1 - 1.4e-13 50.9 0.5 2.2e-13 50.3 0.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Polyketide_cyc2 PF10604.9 PRP89573.1 - 6e-11 42.8 0.1 6.6e-11 42.7 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ank_5 PF13857.6 PRP89574.1 - 7.1e-15 54.9 0.0 4.7e-10 39.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP89574.1 - 1.9e-14 54.0 0.0 9.5e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP89574.1 - 5e-14 52.5 0.0 1.5e-12 47.8 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 PRP89574.1 - 5.6e-11 42.4 0.0 6.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 PRP89574.1 - 2.6e-08 33.5 0.0 7.3e-06 26.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat DnaJ PF00226.31 PRP89575.1 - 5.3e-16 58.5 0.5 5.3e-16 58.5 0.5 1.7 2 0 0 2 2 2 1 DnaJ domain SH2 PF00017.24 PRP89576.1 - 6.2e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 SH2 domain Ndufs5 PF10200.9 PRP89577.1 - 0.00022 21.4 0.2 0.00027 21.1 0.2 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 PRP89577.1 - 0.019 15.1 3.6 0.027 14.6 3.6 1.3 1 0 0 1 1 1 0 CHCH domain DUF3128 PF11326.8 PRP89577.1 - 0.037 14.4 3.4 0.52 10.7 3.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) GCK PF07802.11 PRP89577.1 - 0.042 14.3 1.9 0.31 11.5 1.9 1.9 1 1 0 1 1 1 0 GCK domain AAA_16 PF13191.6 PRP89578.1 - 2.7e-38 132.0 0.0 8.4e-38 130.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.25 PRP89578.1 - 9.3e-27 94.0 0.4 9.3e-27 94.0 0.4 2.1 3 0 0 3 3 3 1 Protein kinase domain HATPase_c PF02518.26 PRP89578.1 - 5.2e-25 88.1 0.1 4.3e-24 85.2 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP89578.1 - 3.2e-24 85.2 0.2 8.7e-24 83.9 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase_Tyr PF07714.17 PRP89578.1 - 3.1e-21 75.8 0.1 9.1e-21 74.3 0.1 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase GAF PF01590.26 PRP89578.1 - 1.1e-11 45.5 0.0 2.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 PRP89578.1 - 2.6e-07 30.6 0.0 2.6e-06 27.4 0.0 2.8 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 PRP89578.1 - 3.9e-07 30.4 0.0 1.1e-06 29.0 0.0 1.8 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 PRP89578.1 - 9e-05 22.3 1.5 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RsgA_GTPase PF03193.16 PRP89578.1 - 0.0032 17.4 0.6 0.017 15.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase Sigma54_activat PF00158.26 PRP89578.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain SpoVT_C PF15714.5 PRP89578.1 - 0.014 15.4 0.2 0.082 13.0 0.2 2.4 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor NACHT PF05729.12 PRP89578.1 - 0.1 12.5 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF4413 PF14372.6 PRP89578.1 - 0.27 11.6 1.8 0.88 10.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4413) NYN_YacP PF05991.11 PRP89579.1 - 0.007 16.3 0.1 0.0092 15.9 0.1 1.2 1 0 0 1 1 1 1 YacP-like NYN domain DUF2911 PF11138.8 PRP89579.1 - 0.012 15.5 0.4 0.014 15.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2911) Elongin_A PF06881.11 PRP89579.1 - 0.015 15.8 1.9 0.16 12.5 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Methyltransf_30 PF05430.11 PRP89579.1 - 0.037 13.9 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF3656 PF12392.8 PRP89579.1 - 0.11 13.1 1.4 0.14 12.8 1.4 1.1 1 0 0 1 1 1 0 Collagenase RPAP3_C PF13877.6 PRP89580.1 - 3e-24 85.4 0.8 5.6e-24 84.5 0.2 1.8 2 0 0 2 2 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 PRP89580.1 - 5.8e-22 76.5 0.2 6.9e-07 28.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PRP89580.1 - 1.7e-15 55.8 0.3 0.00013 21.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 PRP89580.1 - 3.3e-10 39.5 0.8 1.9e-06 27.4 0.0 3.1 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 PRP89580.1 - 8.3e-08 31.9 1.5 0.00049 20.1 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PRP89580.1 - 1.8e-07 31.0 0.0 0.0031 17.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PRP89580.1 - 1.6e-05 25.5 0.0 0.018 15.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 PRP89580.1 - 5.4e-05 23.3 0.0 0.0021 18.2 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 PRP89580.1 - 0.0023 17.8 0.1 1 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PRP89580.1 - 0.0025 18.5 0.0 0.49 11.3 0.0 2.9 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PRP89580.1 - 0.009 16.3 1.8 0.55 10.5 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF2151 PF10221.9 PRP89580.1 - 1.1 7.8 22.4 0.013 14.1 11.4 2.2 2 0 0 2 2 2 0 Cell cycle and development regulator CLN3 PF02487.17 PRP89580.1 - 1.6 7.7 4.6 3.3 6.6 4.6 1.5 1 0 0 1 1 1 0 CLN3 protein PAS_9 PF13426.7 PRP89581.1 - 9.5e-16 58.0 0.0 5.3e-15 55.6 0.0 2.3 1 0 0 1 1 1 1 PAS domain RasGAP PF00616.19 PRP89581.1 - 7.9e-09 35.5 0.0 7.8e-06 25.7 0.0 2.7 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase SAM_2 PF07647.17 PRP89581.1 - 3.6e-06 27.0 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PRP89581.1 - 0.00041 20.7 0.0 0.0011 19.3 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAS_4 PF08448.10 PRP89581.1 - 0.0011 19.2 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 PRP89581.1 - 0.0021 18.1 0.0 0.0069 16.4 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 PRP89581.1 - 0.03 14.6 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 PAS fold MecA PF05389.12 PRP89581.1 - 0.19 11.4 2.4 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) IRK_C PF17655.1 PRP89582.1 - 3e-22 79.1 0.2 3.4e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PRP89582.1 - 0.037 13.8 9.1 0.38 10.6 9.1 2.1 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 PRP89582.1 - 0.067 13.2 11.8 0.14 12.1 11.5 1.7 1 1 0 1 1 1 0 Ion channel DUF1616 PF07760.11 PRP89582.1 - 0.071 12.5 0.8 0.13 11.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Flavodoxin_3 PF12641.7 PRP89583.1 - 0.072 12.8 1.4 0.36 10.5 0.0 3.1 2 0 0 2 2 2 0 Flavodoxin domain WGG PF10273.9 PRP89583.1 - 0.11 13.2 2.2 7.9 7.2 0.1 4.0 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 TPR_12 PF13424.6 PRP89583.1 - 4.1 7.8 9.1 0.6 10.4 0.2 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L29e PF01779.17 PRP89584.1 - 7.1e-20 71.1 14.7 9.2e-20 70.7 14.7 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family SF3A2 PF16835.5 PRP89585.1 - 1.1e-35 121.8 0.2 1.7e-35 121.2 0.2 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 PRP89585.1 - 4e-07 30.2 1.3 8.9e-07 29.1 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 PRP89585.1 - 6.1e-06 26.2 0.8 9.4e-06 25.6 0.8 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein MRP-L27 PF09809.9 PRP89586.1 - 1.1e-13 51.1 0.1 1.3e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HEAT_EZ PF13513.6 PRP89587.1 - 3.6e-33 113.6 2.6 4.2e-12 46.3 0.0 9.8 10 0 0 10 10 10 4 HEAT-like repeat HEAT PF02985.22 PRP89587.1 - 4e-28 95.1 12.2 5.7e-06 26.1 0.0 11.7 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 PRP89587.1 - 4e-18 65.6 0.0 7.3e-07 29.5 0.0 6.3 5 1 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 PRP89587.1 - 1.7e-15 57.5 0.4 1.1e-05 25.6 0.0 4.8 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PRP89587.1 - 1.7e-10 41.3 0.0 0.044 14.4 0.1 6.7 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 PRP89587.1 - 6.4e-10 38.2 5.0 4e-05 22.4 0.2 4.6 3 1 0 4 4 4 3 Adaptin N terminal region Arm PF00514.23 PRP89587.1 - 2.7e-08 33.6 3.6 0.24 11.5 0.0 6.6 7 0 0 7 7 6 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 PRP89587.1 - 7.7e-08 31.9 1.1 0.29 10.2 0.0 5.1 6 0 0 6 6 6 2 RNAPII transcription regulator C-terminal Xpo1 PF08389.12 PRP89587.1 - 0.00058 20.0 1.1 2.2 8.3 0.1 4.6 3 1 0 4 4 4 1 Exportin 1-like protein CLASP_N PF12348.8 PRP89587.1 - 0.0013 18.4 0.3 12 5.4 0.0 4.9 3 2 1 4 4 4 0 CLASP N terminal IBN_N PF03810.19 PRP89587.1 - 0.0014 18.5 0.0 0.0065 16.4 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3437 PF11919.8 PRP89587.1 - 0.0051 16.7 0.6 0.37 10.8 0.0 4.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) HEAT_PBS PF03130.16 PRP89587.1 - 0.0072 16.9 0.3 35 5.5 0.0 5.2 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 PRP89587.1 - 0.008 16.2 4.1 12 5.8 0.0 4.9 5 0 0 5 5 5 0 Myosin-binding striated muscle assembly central RasGEF_N_2 PF14663.6 PRP89587.1 - 0.01 16.2 1.1 1.8 9.0 0.1 4.5 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain UME PF08064.13 PRP89587.1 - 0.081 12.8 0.2 0.081 12.8 0.2 4.3 6 1 0 6 6 6 0 UME (NUC010) domain Colicin_Pyocin PF01320.18 PRP89587.1 - 0.21 11.7 0.2 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein DUF3361 PF11841.8 PRP89587.1 - 0.23 11.4 1.2 11 5.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3361) DnaJ PF00226.31 PRP89588.1 - 1.4e-24 86.0 2.0 1.4e-24 86.0 2.0 2.1 2 0 0 2 2 2 1 DnaJ domain DUF829 PF05705.14 PRP89589.1 - 1.2e-22 80.9 1.1 5.1e-18 65.9 0.2 2.4 2 1 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) Hydrolase_4 PF12146.8 PRP89589.1 - 0.0035 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIP PF03583.14 PRP89589.1 - 0.031 13.6 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase SURF6 PF04935.12 PRP89590.1 - 4.9e-21 75.5 42.8 9e-21 74.6 42.8 1.4 1 1 0 1 1 1 1 Surfeit locus protein 6 Lactonase PF10282.9 PRP89591.1 - 1.7e-77 261.0 0.8 3.1e-77 260.1 0.8 1.5 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Pkinase_Tyr PF07714.17 PRP89591.1 - 3.7e-74 249.3 0.0 6.2e-74 248.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89591.1 - 2.2e-42 145.2 0.0 3.9e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain VIT PF08487.10 PRP89591.1 - 1.4e-30 105.8 0.1 3.4e-30 104.5 0.1 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 PRP89591.1 - 1.5e-20 73.7 0.0 4.2e-20 72.2 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PRP89591.1 - 1.9e-13 51.0 0.0 1.4e-12 48.2 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 PRP89591.1 - 1.1e-10 41.3 0.0 1.1e-10 41.3 0.0 2.5 3 0 0 3 3 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.6 PRP89591.1 - 8.1e-10 39.3 0.0 7.6e-09 36.2 0.0 2.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Chitin_bind_1 PF00187.19 PRP89591.1 - 5.7e-08 33.1 35.2 1.1e-05 25.8 11.8 3.1 2 1 1 3 3 2 2 Chitin recognition protein DUF3471 PF11954.8 PRP89591.1 - 0.023 15.2 0.2 1.7 9.2 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3471) VWA_CoxE PF05762.14 PRP89591.1 - 0.031 13.7 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Kdo PF06293.14 PRP89591.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP89591.1 - 0.24 11.3 0.0 0.41 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FixQ PF05545.11 PRP89591.1 - 5.6 7.0 5.1 0.85 9.6 0.1 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ubiquitin PF00240.23 PRP89593.1 - 9.4e-137 445.0 23.0 9.5e-34 115.0 0.9 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 PRP89593.1 - 1.9e-63 210.2 24.0 1.9e-15 56.4 1.0 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP89593.1 - 4.7e-24 84.7 12.3 0.00016 22.0 0.2 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 PRP89593.1 - 2e-16 59.7 5.8 0.017 15.0 0.1 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP89593.1 - 2.6e-15 56.5 4.5 0.054 13.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PRP89593.1 - 3.3e-15 56.5 1.6 0.085 13.4 0.0 4.1 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP89593.1 - 1.7e-14 54.0 10.7 0.026 14.9 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 PRP89593.1 - 1.4e-10 41.2 0.4 0.84 9.5 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 PRP89593.1 - 1.8e-07 31.1 25.7 11 6.2 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain DUF3861 PF12977.7 PRP89593.1 - 7.9e-07 29.2 3.9 6.9 6.9 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 PRP89593.1 - 8.1e-06 26.1 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 PRP89593.1 - 1.1e-05 24.9 0.8 2.6 7.3 0.0 3.2 3 0 0 3 3 3 3 RNA methyltransferase TmoB PF06234.12 PRP89593.1 - 1.7e-05 24.8 0.0 32 4.7 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) DUF493 PF04359.14 PRP89593.1 - 3.3e-05 24.4 0.1 44 4.8 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Big_7 PF17957.1 PRP89593.1 - 8.7e-05 23.2 0.1 63 4.4 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain Big_3_3 PF13750.6 PRP89593.1 - 9.1e-05 22.2 0.1 31 4.2 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) DUF1940 PF09155.10 PRP89593.1 - 0.00015 21.9 5.5 18 5.4 0.1 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF1940) UDP-g_GGTase PF06427.11 PRP89593.1 - 0.00018 21.6 4.7 7.1 6.8 0.1 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 PRP89593.1 - 0.00019 21.2 6.5 15 5.5 0.1 4.3 4 0 0 4 4 4 0 ACT domain Raf1_HTH PF18579.1 PRP89593.1 - 0.0002 21.0 1.4 37 4.1 0.0 4.2 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain DUF969 PF06149.12 PRP89593.1 - 0.00046 19.7 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 PRP89593.1 - 0.0013 19.2 1.9 85 3.8 0.0 4.3 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 PRP89593.1 - 0.003 17.6 0.0 91 3.3 0.0 4.9 4 0 0 4 4 4 0 ORF11CD3 domain Baculo_p48 PF04878.13 PRP89593.1 - 0.007 15.4 0.1 24 3.7 0.0 3.2 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 PRP89593.1 - 0.031 14.4 6.3 70 3.7 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 PRP89593.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif PI3K_p85B PF02192.16 PRP89593.1 - 0.15 11.8 11.0 37 4.2 0.1 4.3 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Myosin_N PF02736.19 PRP89593.1 - 0.31 10.9 6.3 1.1e+02 2.8 0.0 5.0 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 PRP89593.1 - 1.7 8.3 3.5 2.4e+02 1.4 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 Phage_sheath_1N PF17481.2 PRP89593.1 - 2.4 8.7 9.2 1.5e+02 2.9 0.1 3.9 1 1 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 PRP89593.1 - 3.3 6.3 20.6 9.5 4.7 0.6 5.0 5 3 0 5 5 5 0 Plexin cytoplasmic RasGAP domain bZIP_1 PF00170.21 PRP89594.1 - 0.06 13.5 18.4 0.11 12.6 4.6 3.2 2 1 1 3 3 3 0 bZIP transcription factor Nitroreductase PF00881.24 PRP89594.1 - 0.074 13.1 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Nitroreductase family Vac_Fusion PF02346.16 PRP89594.1 - 1.4 8.6 7.3 10 5.8 1.4 3.1 2 1 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 NYD-SP28_assoc PF14775.6 PRP89594.1 - 2.3 8.4 7.2 17 5.6 0.5 3.1 2 1 1 3 3 3 0 Sperm tail C-terminal domain Shugoshin_N PF07558.11 PRP89594.1 - 2.9 7.8 13.7 0.25 11.3 0.3 3.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Rootletin PF15035.6 PRP89594.1 - 3.8 7.5 27.5 1.7 8.6 18.0 2.7 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion PAN_4 PF14295.6 PRP89596.1 - 7.8e-11 41.7 32.6 9.5e-09 35.0 6.6 3.4 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 PRP89596.1 - 2.7e-05 24.1 11.0 0.0046 16.9 0.8 2.5 2 0 0 2 2 2 2 PAN domain SH3_15 PF18346.1 PRP89596.1 - 0.028 14.7 0.2 0.062 13.6 0.2 1.6 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain B_lectin PF01453.24 PRP89596.1 - 0.032 14.8 0.0 6 7.5 0.1 2.2 1 1 1 2 2 2 0 D-mannose binding lectin PAN_2 PF08276.11 PRP89596.1 - 0.092 12.9 21.3 1.4 9.1 4.7 2.9 2 0 0 2 2 2 0 PAN-like domain PRR18 PF15671.5 PRP89596.1 - 4.8 7.0 10.7 11 5.8 10.7 1.6 1 0 0 1 1 1 0 Proline-rich protein family 18 RAP1 PF07218.11 PRP89596.1 - 8.1 4.6 13.7 11 4.2 13.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MutS_V PF00488.21 PRP89597.1 - 2.4e-71 239.7 0.4 3.7e-71 239.1 0.4 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PRP89597.1 - 3.8e-29 102.3 0.4 3.9e-28 99.0 0.0 2.6 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.20 PRP89597.1 - 1.9e-22 79.7 0.0 4.5e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 PRP89597.1 - 5.7e-06 26.7 0.1 5.8e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 PRP89597.1 - 0.00057 20.2 0.2 0.0013 19.0 0.2 1.7 1 0 0 1 1 1 1 MutS family domain IV RALF PF05498.11 PRP89597.1 - 0.18 12.8 0.1 0.53 11.3 0.1 1.8 1 0 0 1 1 1 0 Rapid ALkalinization Factor (RALF) BAG PF02179.16 PRP89598.1 - 7.2e-09 36.0 4.5 3.1e-08 33.9 4.5 2.2 1 1 0 1 1 1 1 BAG domain Ribosomal_L24e PF01246.20 PRP89599.1 - 2.1e-33 114.3 3.8 2.1e-33 114.3 3.8 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e Arc_trans_TRASH PF08394.10 PRP89599.1 - 0.16 12.3 2.5 0.42 11.0 2.5 1.8 1 0 0 1 1 1 0 Archaeal TRASH domain DUF2175 PF09943.9 PRP89599.1 - 5.7 7.3 13.2 0.5 10.7 0.3 3.2 1 1 3 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) DNA_pol_phi PF04931.13 PRP89600.1 - 1.5e-15 56.4 27.9 1.5e-15 56.4 27.9 4.1 1 1 1 3 3 3 1 DNA polymerase phi ACC_epsilon PF13822.6 PRP89600.1 - 0.076 13.7 0.1 0.23 12.2 0.1 1.8 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit PspB PF06667.12 PRP89600.1 - 4.5 7.4 7.7 0.7 10.0 0.8 3.4 4 0 0 4 4 4 0 Phage shock protein B Asparaginase_2 PF01112.18 PRP89601.1 - 4e-56 190.3 0.2 5.8e-56 189.8 0.2 1.3 1 0 0 1 1 1 1 Asparaginase IDO PF01231.18 PRP89602.1 - 0.0014 17.5 0.1 0.24 10.1 0.1 2.2 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase HATPase_c PF02518.26 PRP89603.1 - 1.9e-52 176.5 0.6 7.9e-25 87.5 0.1 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PRP89603.1 - 3.1e-50 169.0 0.2 1.2e-26 93.1 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 PRP89603.1 - 3.2e-23 81.6 5.5 1.1e-11 44.5 0.6 3.0 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PRP89603.1 - 2.9e-06 27.1 0.0 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 PRP89603.1 - 0.00017 21.8 0.0 0.00058 20.1 0.0 1.9 1 0 0 1 1 1 1 PAS fold SurE PF01975.17 PRP89604.1 - 2e-51 174.5 0.0 2.6e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE SNARE PF05739.19 PRP89605.1 - 1.1e-10 41.4 1.4 2.5e-10 40.2 1.4 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 PRP89605.1 - 0.00019 21.2 10.6 0.00091 19.0 10.6 2.0 1 1 0 1 1 1 1 Syntaxin Csm1_N PF18504.1 PRP89605.1 - 0.037 14.4 12.3 0.61 10.5 2.2 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF4047 PF13256.6 PRP89605.1 - 0.18 12.0 3.6 1.3 9.3 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) SKA1 PF07160.12 PRP89605.1 - 1.1 9.1 12.1 0.7 9.7 1.3 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4795 PF16043.5 PRP89605.1 - 1.3 8.6 12.8 0.17 11.5 1.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 PRP89605.1 - 2.5 8.8 10.5 0.45 11.2 1.5 3.2 3 0 0 3 3 3 0 SlyX L31 PF09784.9 PRP89605.1 - 4.1 7.9 7.5 8.3 6.9 0.1 3.7 3 2 0 3 3 3 0 Mitochondrial ribosomal protein L31 DUF1664 PF07889.12 PRP89605.1 - 6.3 6.9 9.3 13 5.8 0.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 PRP89605.1 - 7.4 6.9 12.0 0.22 11.8 0.8 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 TMPIT PF07851.13 PRP89605.1 - 7.4 5.7 9.7 6.6 5.9 2.4 2.4 1 1 1 2 2 2 0 TMPIT-like protein TRAP-gamma PF07074.12 PRP89608.1 - 0.032 13.8 0.1 0.032 13.8 0.1 2.2 2 1 1 3 3 3 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF3995 PF13160.6 PRP89608.1 - 0.18 12.2 2.5 2.1 8.7 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3995) Sigma_reg_N PF13800.6 PRP89608.1 - 2.3 8.5 10.1 0.23 11.8 1.4 3.3 3 0 0 3 3 3 0 Sigma factor regulator N-terminal DUF4131 PF13567.6 PRP89608.1 - 3.6 7.2 5.9 5.5 6.6 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) IBR PF01485.21 PRP89612.1 - 4.2e-15 55.7 17.6 5e-10 39.4 3.5 5.2 5 0 0 5 5 5 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 PRP89612.1 - 0.0012 18.8 8.9 0.0012 18.8 8.9 3.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 PRP89612.1 - 0.0024 18.2 9.6 0.0024 18.2 9.6 5.4 5 1 0 5 5 5 2 Ring finger domain zf-C3HC4_2 PF13923.6 PRP89612.1 - 0.0029 17.4 10.0 0.0029 17.4 10.0 5.4 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) EF-hand_7 PF13499.6 PRP89612.1 - 0.11 13.0 1.2 1.2 9.6 0.2 2.9 3 0 0 3 3 3 0 EF-hand domain pair Tautomerase_2 PF14552.6 PRP89612.1 - 0.17 12.0 0.2 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Tautomerase enzyme zf-RanBP PF00641.18 PRP89612.1 - 4.7 6.6 18.4 0.014 14.7 6.9 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Claudin_2 PF13903.6 PRP89613.1 - 0.019 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TMCCDC2 PF15844.5 PRP89613.1 - 0.05 13.5 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 DUF2457 PF10446.9 PRP89613.1 - 0.23 10.6 2.2 0.27 10.4 2.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF327 PF03885.13 PRP89614.1 - 0.039 13.9 0.1 0.098 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF327) RasGEF PF00617.19 PRP89615.1 - 1.7e-52 178.2 0.2 1.7e-52 178.2 0.2 2.2 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 PRP89615.1 - 2e-20 73.0 2.5 6e-20 71.4 2.5 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif AAA_lid_1 PF17857.1 PRP89615.1 - 0.037 14.2 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA+ lid domain Cupin_8 PF13621.6 PRP89615.1 - 0.24 11.1 1.8 0.44 10.2 1.8 1.3 1 0 0 1 1 1 0 Cupin-like domain LapA_dom PF06305.11 PRP89615.1 - 0.27 11.1 2.0 0.37 10.6 0.3 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Peroxin-13_N PF04088.13 PRP89615.1 - 1.8 8.9 4.4 11 6.3 2.3 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region WD40 PF00400.32 PRP89616.1 - 2.3e-43 145.3 18.9 2.7e-05 24.9 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PRP89616.1 - 1.5e-15 57.2 0.1 0.0023 18.2 0.0 6.2 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PRP89616.1 - 5.8e-06 25.5 0.3 0.31 9.9 0.0 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PRP89616.1 - 4.8e-05 22.2 4.3 0.034 12.8 0.1 3.4 2 1 2 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 PRP89616.1 - 0.027 14.4 2.4 4.8 7.2 0.5 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 PRP89616.1 - 0.033 12.7 1.0 0.3 9.6 0.3 2.5 2 1 1 3 3 3 0 Cytochrome D1 heme domain Ints3 PF10189.9 PRP89617.1 - 1.8e-82 276.0 1.6 5.5e-82 274.4 1.6 1.9 1 0 0 1 1 1 1 Integrator complex subunit 3 SPC25 PF06703.11 PRP89618.1 - 7.2e-27 94.1 0.0 8.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF5504 PF17608.2 PRP89618.1 - 0.047 13.8 1.1 0.07 13.2 1.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5504) F-box-like PF12937.7 PRP89619.1 - 0.0026 17.6 0.1 0.0045 16.8 0.1 1.3 1 0 0 1 1 1 1 F-box-like Ank_3 PF13606.6 PRP89619.1 - 0.012 16.1 0.0 0.094 13.3 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 PRP89619.1 - 0.027 15.1 0.0 0.22 12.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) 6PF2K PF01591.18 PRP89620.1 - 2.9e-78 262.2 0.9 4.8e-78 261.5 0.9 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 PRP89620.1 - 9.5e-38 129.8 0.0 1.7e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AIP3 PF03915.13 PRP89620.1 - 5.8e-12 45.4 0.2 1.2e-11 44.4 0.2 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 AAA_33 PF13671.6 PRP89620.1 - 1.8e-05 24.9 0.1 3.9e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 PRP89620.1 - 0.003 17.0 0.2 0.016 14.7 0.2 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AROS PF15684.5 PRP89620.1 - 0.024 15.2 0.1 0.055 14.0 0.1 1.6 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 COesterase PF00135.28 PRP89622.1 - 1.1e-82 278.6 0.0 1.4e-82 278.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 PRP89622.1 - 0.00056 19.4 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 PRP89622.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 PRP89622.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LRR_6 PF13516.6 PRP89623.1 - 1.7e-16 58.8 7.9 7.5e-07 28.7 0.1 4.9 4 0 0 4 4 4 4 Leucine Rich repeat LRR_4 PF12799.7 PRP89623.1 - 1.2e-05 25.5 14.7 0.065 13.7 1.3 4.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) SHE3 PF17078.5 PRP89623.1 - 0.0013 18.5 20.5 0.0028 17.4 20.5 1.6 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 LRR_1 PF00560.33 PRP89623.1 - 0.0031 17.8 5.3 6.8 7.7 0.4 4.7 3 2 0 3 3 3 1 Leucine Rich Repeat Seadorna_VP6 PF07407.11 PRP89623.1 - 0.008 15.2 2.6 0.013 14.5 2.6 1.2 1 0 0 1 1 1 1 Seadornavirus VP6 protein LRR_8 PF13855.6 PRP89623.1 - 0.011 15.5 11.0 0.67 9.8 1.2 4.3 2 1 2 4 4 4 0 Leucine rich repeat FAM76 PF16046.5 PRP89623.1 - 0.049 13.0 13.0 0.08 12.3 13.0 1.3 1 0 0 1 1 1 0 FAM76 protein Occludin_ELL PF07303.13 PRP89623.1 - 0.41 11.4 16.0 0.35 11.6 4.0 2.8 2 0 0 2 2 2 0 Occludin homology domain Uso1_p115_C PF04871.13 PRP89623.1 - 2.2 8.6 21.7 0.03 14.7 4.9 2.6 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 PRP89623.1 - 4.4 8.0 14.4 0.51 11.0 0.4 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Homeodomain PF00046.29 PRP89624.1 - 2e-28 98.0 2.0 3.5e-11 42.8 0.0 3.4 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 PRP89624.1 - 2.6e-09 36.8 0.3 0.009 15.9 0.0 3.9 4 0 0 4 4 4 3 Homeobox KN domain Homez PF11569.8 PRP89624.1 - 1.9e-05 24.0 4.0 0.2 11.1 0.1 3.9 3 1 1 4 4 4 3 Homeodomain leucine-zipper encoding, Homez Pkinase PF00069.25 PRP89625.1 - 2.1e-75 253.5 0.0 2.4e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89625.1 - 8e-32 110.5 0.0 1.2e-31 109.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP89625.1 - 2.1e-05 24.0 0.1 0.00054 19.4 0.0 2.4 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PRP89625.1 - 0.0003 19.8 0.0 0.0021 17.0 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PRP89625.1 - 0.006 16.0 0.1 0.016 14.6 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PRP89625.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 PRP89625.1 - 0.044 13.7 0.1 0.08 12.8 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 PRP89625.1 - 0.053 13.1 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 PRP89625.1 - 0.082 12.5 0.0 4.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HXXSHH PF07586.11 PRP89626.1 - 0.045 13.3 0.4 0.085 12.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) AAA_6 PF12774.7 PRP89626.1 - 0.073 12.0 0.7 0.17 10.9 0.7 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region IL5 PF02025.15 PRP89626.1 - 0.56 10.5 5.0 0.37 11.1 0.4 2.8 2 1 1 3 3 3 0 Interleukin 5 PNPase PF03726.14 PRP89626.1 - 1 9.9 8.7 0.19 12.2 2.7 2.7 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PA14 PF07691.12 PRP89627.1 - 1.4e-13 50.9 0.2 3e-13 49.8 0.0 1.5 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.18 PRP89627.1 - 0.00075 19.4 3.8 0.00075 19.4 3.8 19.2 19 1 1 20 20 20 11 Dictyostelium (slime mold) repeat Ank_2 PF12796.7 PRP89628.1 - 4.7e-22 78.4 0.0 3.4e-06 27.5 0.0 4.4 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP89628.1 - 6e-11 42.7 0.5 0.12 13.0 0.0 5.1 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP89628.1 - 4.2e-10 39.0 0.2 7.9 7.4 0.0 8.1 8 1 1 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 PRP89628.1 - 9.9e-10 38.5 1.0 2.6 8.5 0.0 8.3 6 3 3 9 9 9 2 Ankyrin repeats (many copies) Ank PF00023.30 PRP89628.1 - 5.7e-08 32.9 3.0 1.7 9.2 0.0 7.4 7 1 1 8 8 8 2 Ankyrin repeat Pkinase PF00069.25 PRP89629.1 - 9.2e-68 228.4 0.0 1.6e-67 227.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89629.1 - 2.2e-31 109.1 0.0 3.4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 PRP89629.1 - 2e-06 28.4 3.1 2e-06 28.4 3.1 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 PRP89629.1 - 1.9e-05 24.9 0.0 3.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 PRP89629.1 - 0.00024 20.5 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YabA PF06156.13 PRP89629.1 - 9.6 6.9 6.8 36 5.1 0.1 3.0 3 0 0 3 3 3 0 Initiation control protein YabA ICMT PF04140.14 PRP89630.1 - 0.0081 16.6 0.2 0.0081 16.6 0.2 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family WD40 PF00400.32 PRP89631.1 - 1.2e-07 32.3 1.8 0.24 12.3 0.1 4.7 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF948 PF06103.11 PRP89631.1 - 0.35 11.1 4.0 0.12 12.6 1.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Aha1_N PF09229.11 PRP89632.1 - 5.7e-32 110.8 4.3 1.2e-31 109.7 4.3 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 PRP89632.1 - 1.4e-17 64.1 0.1 1.4e-17 64.1 0.1 2.2 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein TAFH PF07531.14 PRP89632.1 - 0.0022 18.1 0.1 0.0058 16.7 0.1 1.6 1 0 0 1 1 1 1 NHR1 homology to TAF DUF4516 PF14990.6 PRP89633.1 - 0.0039 16.9 0.1 0.0053 16.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4516) DUF5552 PF17706.1 PRP89635.1 - 0.059 13.1 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5552) Guanylate_cyc PF00211.20 PRP89636.1 - 1.5e-29 102.9 0.5 3.5e-29 101.7 0.1 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain GTP_EFTU PF00009.27 PRP89637.1 - 5e-56 189.3 0.1 6.5e-56 188.9 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PRP89637.1 - 3.9e-24 85.1 0.0 7.4e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PRP89637.1 - 1.1e-12 48.2 6.0 2.8e-12 46.8 6.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PRP89637.1 - 5.3e-05 23.3 0.0 9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 PRP89637.1 - 0.024 14.2 0.0 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 PRP89637.1 - 0.048 13.6 0.0 0.19 11.6 0.0 1.9 1 1 1 2 2 2 0 RsgA GTPase HhH-GPD PF00730.25 PRP89637.1 - 0.072 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Ribosomal_S8 PF00410.19 PRP89637.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S8 Glyco_hydro_46 PF01374.18 PRP89638.1 - 7.8e-37 126.9 0.1 1.2e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 PAN_4 PF14295.6 PRP89638.1 - 7.5e-08 32.2 4.3 2.2e-07 30.7 4.3 1.9 1 0 0 1 1 1 1 PAN domain FR47 PF08445.10 PRP89638.1 - 1.7e-05 24.7 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein PAN_1 PF00024.26 PRP89638.1 - 4.3e-05 23.4 2.5 0.0001 22.2 2.5 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 PRP89638.1 - 0.0049 16.9 2.3 0.012 15.7 2.3 1.6 1 0 0 1 1 1 1 PAN-like domain Acyl-CoA_dh_1 PF00441.24 PRP89639.1 - 5.1e-41 140.4 0.7 7.6e-41 139.8 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PRP89639.1 - 1e-21 76.9 0.1 2.4e-21 75.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PRP89639.1 - 5.4e-19 68.9 0.0 1.6e-18 67.4 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 PRP89639.1 - 1.7e-18 66.5 0.0 3.7e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 PRP89639.1 - 1.1e-06 29.0 0.3 2.2e-06 28.0 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UIM PF02809.20 PRP89641.1 - 0.0012 18.7 7.0 0.022 14.6 3.6 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif PIP5K PF01504.18 PRP89642.1 - 3.5e-84 282.3 2.2 7.2e-84 281.2 0.3 2.2 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Ribosomal_S27e PF01667.17 PRP89643.1 - 2.6e-28 97.5 3.8 3.3e-28 97.2 3.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 PRP89643.1 - 0.02 15.3 1.2 0.16 12.4 1.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) IBR PF01485.21 PRP89643.1 - 0.027 14.7 0.8 0.04 14.1 0.8 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Prok-RING_1 PF14446.6 PRP89643.1 - 0.16 11.9 3.8 0.26 11.2 3.8 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.12 PRP89643.1 - 0.38 10.3 4.7 0.68 9.5 4.7 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding UCH PF00443.29 PRP89644.1 - 6.8e-34 117.5 4.2 1.4e-33 116.5 4.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PRP89644.1 - 2.5e-06 27.3 10.3 0.0019 17.9 0.0 3.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 PRP89644.1 - 1.1e-05 25.1 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 PRP89644.1 - 0.019 14.9 1.3 0.051 13.5 1.3 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Fez1 PF06818.15 PRP89644.1 - 8.6 6.8 18.9 0.027 14.9 8.5 2.1 3 0 0 3 3 3 0 Fez1 DUF2070 PF09843.9 PRP89645.1 - 7.1 4.8 8.0 8.6 4.5 8.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AMP-binding PF00501.28 PRP89646.1 - 3.2e-92 309.3 0.0 4.8e-92 308.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PRP89646.1 - 9.2e-12 45.8 0.0 1.2e-10 42.2 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 PRP89646.1 - 3e-11 42.6 5.8 5.9e-05 22.6 0.2 6.4 6 1 0 6 6 6 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PRP89646.1 - 1e-06 28.4 9.2 0.0014 18.4 0.4 4.3 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase PP-binding PF00550.25 PRP89646.1 - 0.0027 18.0 0.0 0.0062 16.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site BTB PF00651.31 PRP89647.1 - 7.3e-14 51.9 1.2 2.2e-13 50.4 0.6 2.1 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.16 PRP89647.1 - 5.8e-09 35.3 9.6 8.2e-09 34.8 9.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CCCH PF00642.24 PRP89647.1 - 9.9e-05 22.1 1.2 0.0002 21.2 1.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sugar_tr PF00083.24 PRP89647.1 - 0.00026 20.0 0.7 0.0004 19.4 0.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 PRP89647.1 - 0.00033 19.4 2.9 0.00057 18.6 2.9 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein zf_CCCH_4 PF18345.1 PRP89647.1 - 0.0015 18.5 0.5 0.0036 17.3 0.5 1.7 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 PRP89647.1 - 0.0043 17.7 0.1 0.0096 16.6 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 PRP89647.1 - 0.019 14.7 1.3 0.048 13.5 1.3 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger MFS_1_like PF12832.7 PRP89647.1 - 0.036 12.9 0.1 0.04 12.8 0.1 1.1 1 0 0 1 1 1 0 MFS_1 like family RLI PF04068.15 PRP89647.1 - 0.082 12.7 1.0 0.2 11.5 1.0 1.7 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI LacY_symp PF01306.19 PRP89647.1 - 0.1 11.3 1.2 0.16 10.7 1.2 1.2 1 0 0 1 1 1 0 LacY proton/sugar symporter MYCBPAP PF14646.6 PRP89648.1 - 4.6e-27 95.1 7.6 4.6e-27 95.1 7.6 4.9 3 1 0 3 3 3 1 MYCBP-associated protein family zf-CCCH_4 PF18044.1 PRP89650.1 - 0.031 14.1 4.3 0.082 12.7 4.3 1.7 1 1 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PRP89650.1 - 0.13 12.8 6.9 0.26 11.8 6.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Inositol_P PF00459.25 PRP89651.1 - 4.7e-40 137.8 0.0 5.7e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Pkinase_Tyr PF07714.17 PRP89652.1 - 3.3e-70 236.3 0.0 4.6e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89652.1 - 8.1e-49 166.4 0.0 1.4e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PRP89652.1 - 1.1e-42 143.2 109.7 9.2e-05 22.7 0.3 18.3 16 3 4 21 21 21 15 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP89652.1 - 2.7e-40 135.9 105.0 2.3e-08 33.6 4.6 14.2 7 3 9 16 16 16 14 Leucine rich repeat LRR_6 PF13516.6 PRP89652.1 - 7.2e-05 22.5 88.0 1.6 8.9 0.0 22.1 24 0 0 24 24 24 3 Leucine Rich repeat Rax2 PF12768.7 PRP89652.1 - 0.003 17.1 0.1 0.003 17.1 0.1 2.4 3 0 0 3 3 3 1 Cortical protein marker for cell polarity LRR_1 PF00560.33 PRP89652.1 - 0.0042 17.4 91.7 29 5.8 0.0 26.0 26 5 1 27 27 27 0 Leucine Rich Repeat LRRNT_2 PF08263.12 PRP89652.1 - 0.043 14.1 3.8 0.15 12.4 3.8 2.0 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Pkinase_fungal PF17667.1 PRP89652.1 - 0.18 10.5 0.0 0.35 9.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 PRP89653.1 - 1.9e-46 158.5 0.0 1.4e-45 155.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89653.1 - 4.1e-32 111.6 0.0 6.3e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP89653.1 - 0.0014 17.5 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PRP89653.1 - 0.0019 17.6 0.0 0.0037 16.6 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family MCM_bind PF09739.9 PRP89654.1 - 5.6e-131 437.8 0.1 2.5e-129 432.4 0.1 2.0 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 PRP89654.1 - 0.011 16.1 0.1 0.023 15.1 0.1 1.6 1 0 0 1 1 1 0 MCM AAA-lid domain Queuosine_synth PF02547.15 PRP89654.1 - 0.048 12.8 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein PMAIP1 PF15150.6 PRP89654.1 - 0.19 11.6 0.1 9 6.2 0.0 2.7 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced ATP11 PF06644.11 PRP89655.1 - 2e-33 116.3 0.2 2.5e-33 116.0 0.2 1.1 1 0 0 1 1 1 1 ATP11 protein ABC_membrane_2 PF06472.15 PRP89656.1 - 7.1e-43 147.0 3.7 9.5e-43 146.5 3.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PRP89656.1 - 2.7e-20 73.3 0.0 6.7e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 PRP89656.1 - 1.9e-10 40.7 4.4 7.6e-10 38.7 4.4 2.1 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_membrane PF00664.23 PRP89656.1 - 4.9e-06 26.4 6.5 1.1e-05 25.2 6.5 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 PRP89656.1 - 0.00028 20.8 0.1 0.00056 19.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 PRP89656.1 - 0.0037 16.7 0.3 0.023 14.1 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 PRP89656.1 - 0.0091 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.23 PRP89656.1 - 0.021 14.9 0.0 0.062 13.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 PRP89656.1 - 0.035 14.5 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SLATT_5 PF18160.1 PRP89656.1 - 0.043 13.1 0.1 0.16 11.3 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 AAA_22 PF13401.6 PRP89656.1 - 0.056 13.7 1.6 0.25 11.6 0.4 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP89656.1 - 0.059 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 PRP89656.1 - 0.061 13.0 0.1 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain PRRSV_2b PF07069.11 PRP89656.1 - 0.065 13.7 4.2 0.16 12.5 4.2 1.6 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b AAA_21 PF13304.6 PRP89656.1 - 0.11 12.3 1.2 0.69 9.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system COesterase PF00135.28 PRP89657.1 - 2.1e-84 284.2 0.0 3.3e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 PRP89657.1 - 0.0015 18.4 0.3 0.22 11.4 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ank_2 PF12796.7 PRP89657.1 - 0.022 15.3 0.2 4.5 7.9 0.1 2.5 1 1 0 2 2 2 0 Ankyrin repeats (3 copies) SAP PF02037.27 PRP89659.1 - 2.8e-09 36.5 1.3 4.8e-09 35.8 1.3 1.4 1 0 0 1 1 1 1 SAP domain BUD22 PF09073.10 PRP89659.1 - 0.029 13.7 12.5 0.041 13.2 12.5 1.1 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 PRP89659.1 - 0.075 13.1 11.0 0.95 9.5 4.3 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal TFIIF_alpha PF05793.12 PRP89659.1 - 0.22 10.1 19.6 0.33 9.5 19.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNase_H2_suC PF08615.11 PRP89659.1 - 0.37 11.0 1.9 5.9 7.1 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cwf_Cwc_15 PF04889.12 PRP89659.1 - 1.6 8.4 25.3 0.66 9.7 6.8 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 PRP89659.1 - 5.6 6.8 15.8 6.1 6.7 4.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region ELH PF02323.15 PRP89659.1 - 7.6 5.8 11.2 0.072 12.5 0.9 2.4 3 0 0 3 3 3 0 Egg-laying hormone precursor CDC45 PF02724.14 PRP89659.1 - 7.7 4.7 10.1 2.1 6.6 2.3 2.0 2 0 0 2 2 2 0 CDC45-like protein 4F5 PF04419.14 PRP89661.1 - 7.1e-06 26.8 9.5 1.3e-05 25.9 9.5 1.5 1 0 0 1 1 1 1 4F5 protein family zf-met PF12874.7 PRP89661.1 - 0.0012 19.1 0.2 0.0025 18.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-met2 PF12907.7 PRP89661.1 - 0.024 14.8 0.4 0.052 13.7 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding zf-C2H2 PF00096.26 PRP89661.1 - 0.057 13.9 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 PRP89661.1 - 0.12 12.7 1.5 0.22 11.9 1.5 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ribosomal_L32e PF01655.18 PRP89662.1 - 1.1e-45 154.5 0.5 1.3e-45 154.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 UQ_con PF00179.26 PRP89663.1 - 1.9e-38 131.2 0.0 5.1e-17 61.8 0.0 3.3 3 0 0 3 3 3 3 Ubiquitin-conjugating enzyme UEV PF05743.13 PRP89663.1 - 0.00073 19.4 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 UEV domain PIF1 PF05970.14 PRP89664.1 - 3.8e-53 181.0 1.7 7.3e-40 137.2 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 PRP89664.1 - 1e-21 77.5 0.0 2.1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PRP89664.1 - 7.7e-12 45.8 0.0 3.5e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cauli_VI PF01693.16 PRP89664.1 - 7.5e-07 29.4 0.8 1.7e-06 28.2 0.8 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin Herpes_Helicase PF02689.14 PRP89664.1 - 3.2e-05 22.1 0.1 0.0014 16.7 0.0 2.4 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 PRP89664.1 - 0.00015 21.3 0.1 0.00029 20.4 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein Viral_helicase1 PF01443.18 PRP89664.1 - 0.00017 21.4 2.7 0.083 12.6 0.0 3.5 3 1 0 3 3 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 PRP89664.1 - 0.0003 21.1 2.4 0.021 15.1 0.1 3.3 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 PRP89664.1 - 0.001 19.0 0.4 0.043 13.7 0.2 2.6 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.6 PRP89664.1 - 0.0019 18.6 0.1 0.004 17.5 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 PRP89664.1 - 0.0047 16.9 0.1 0.013 15.5 0.1 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 PRP89664.1 - 0.0063 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase MeaB PF03308.16 PRP89664.1 - 0.0082 15.1 0.2 0.0082 15.1 0.2 1.7 2 0 0 2 2 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 PRP89664.1 - 0.009 15.1 0.2 0.016 14.3 0.2 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 PRP89664.1 - 0.0093 14.9 0.1 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Bac_DnaA PF00308.18 PRP89664.1 - 0.012 15.4 0.0 3 7.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein AAA PF00004.29 PRP89664.1 - 0.026 15.0 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 PRP89664.1 - 0.034 13.7 0.0 0.034 13.7 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain NACHT PF05729.12 PRP89664.1 - 0.034 14.1 0.1 0.092 12.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 PRP89664.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 PRP89664.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 PRP89664.1 - 0.045 13.7 0.1 0.13 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PRP89664.1 - 0.075 12.7 1.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 PRP89664.1 - 0.08 12.8 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Microtub_bd PF16796.5 PRP89664.1 - 0.1 12.5 1.7 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Microtubule binding Sigma54_activat PF00158.26 PRP89664.1 - 0.13 11.9 0.1 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain SAVED PF18145.1 PRP89664.1 - 0.15 11.8 1.4 6.8 6.5 0.2 2.5 2 0 0 2 2 2 0 SMODS-associated and fused to various effectors sensor domain Cauli_AT PF03233.13 PRP89664.1 - 7.5 6.5 9.7 0.15 12.0 1.7 2.2 3 0 0 3 3 2 0 Aphid transmission protein UAF_Rrn10 PF05234.11 PRP89666.1 - 0.012 15.9 0.0 1.9 8.7 0.0 2.0 2 0 0 2 2 2 0 UAF complex subunit Rrn10 APH PF01636.23 PRP89668.1 - 3.1e-11 43.7 0.1 8e-11 42.3 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 PRP89668.1 - 2.1e-05 24.0 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 PRP89668.1 - 2.2e-05 23.5 0.0 3.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DNA_gyraseA_C PF03989.13 PRP89668.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller p450 PF00067.22 PRP89669.1 - 3.2e-51 174.5 0.0 3.9e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRR_8 PF13855.6 PRP89670.1 - 5.8e-59 195.7 119.4 1.6e-08 34.2 2.7 16.6 11 4 3 16 16 16 15 Leucine rich repeat Pkinase_Tyr PF07714.17 PRP89670.1 - 8.6e-46 156.3 0.0 4.7e-37 127.7 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PRP89670.1 - 1.8e-41 139.4 126.2 5.9e-05 23.3 3.8 21.0 14 6 7 23 23 23 15 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PRP89670.1 - 8.3e-27 94.2 0.0 5.5e-19 68.6 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain LRR_1 PF00560.33 PRP89670.1 - 5.9e-08 32.2 100.1 0.68 10.7 0.0 26.2 29 3 0 29 29 29 4 Leucine Rich Repeat LRR_6 PF13516.6 PRP89670.1 - 1.8e-06 27.6 103.6 1.8 8.8 0.0 25.2 31 0 0 31 31 31 6 Leucine Rich repeat LRRNT_2 PF08263.12 PRP89670.1 - 0.00027 21.2 0.1 0.0007 19.8 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain SKG6 PF08693.10 PRP89670.1 - 0.0031 16.9 3.7 0.0061 15.9 3.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_5 PF13306.6 PRP89670.1 - 0.12 12.3 27.9 0.46 10.4 0.2 6.6 4 2 1 6 6 6 0 BspA type Leucine rich repeat region (6 copies) Clathrin PF00637.20 PRP89671.1 - 4.8e-09 36.2 16.8 0.002 18.0 0.8 6.2 3 1 3 6 6 6 3 Region in Clathrin and VPS TPR_14 PF13428.6 PRP89671.1 - 7.8e-08 32.5 4.7 4.1 8.5 0.0 7.1 7 1 1 8 8 5 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 PRP89671.1 - 1.4e-05 25.3 0.1 0.038 14.3 0.0 5.5 5 1 2 7 7 5 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 PRP89671.1 - 1.6e-05 24.2 8.5 0.021 13.9 0.3 4.3 3 1 1 4 4 4 2 Coatomer WD associated region Nic96 PF04097.14 PRP89671.1 - 1.8e-05 23.4 0.3 0.093 11.2 0.1 3.7 2 1 0 3 3 3 2 Nup93/Nic96 TPR_2 PF07719.17 PRP89671.1 - 0.00011 22.1 19.7 2.7 8.3 1.2 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 PRP89671.1 - 0.00013 21.9 10.0 2.5 8.5 0.1 6.8 4 1 1 5 5 5 1 Tetratricopeptide repeat Frtz PF11768.8 PRP89671.1 - 0.00041 18.8 0.0 0.029 12.7 0.0 2.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 PRP89671.1 - 0.0015 17.6 0.1 0.35 9.8 0.1 3.1 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain TPR_12 PF13424.6 PRP89671.1 - 0.0018 18.6 14.1 6.4 7.1 0.1 6.8 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 PRP89671.1 - 0.0068 16.9 7.4 1.9 9.0 0.2 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 PRP89671.1 - 0.01 16.0 7.8 4.3 7.8 0.0 6.4 7 1 1 8 8 6 0 PPR repeat SNAP PF14938.6 PRP89671.1 - 0.012 15.0 16.1 0.053 12.9 4.8 4.7 4 1 0 5 5 5 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 PRP89671.1 - 0.027 14.5 9.8 1.8 8.7 0.4 5.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 PRP89671.1 - 0.04 14.0 13.1 13 6.1 0.3 7.3 6 2 1 7 7 7 0 Tetratricopeptide repeat PPR_2 PF13041.6 PRP89671.1 - 0.043 14.0 4.2 2.5 8.4 0.1 4.5 5 0 0 5 5 4 0 PPR repeat family TPR_4 PF07721.14 PRP89671.1 - 0.11 13.2 0.2 3.4 8.6 0.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 PRP89671.1 - 0.12 12.3 8.8 12 5.9 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP89671.1 - 0.55 10.1 20.7 0.92 9.4 1.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR_1 PF12854.7 PRP89671.1 - 0.69 9.7 2.8 11 5.8 0.1 3.9 4 0 0 4 4 4 0 PPR repeat TPR_17 PF13431.6 PRP89671.1 - 1.6 9.2 4.7 85 3.9 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP89671.1 - 2.5 8.8 10.1 79 4.0 0.1 5.1 7 0 0 7 7 4 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.20 PRP89672.1 - 1.8e-45 154.7 0.3 1.3e-44 151.9 0.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PRP89672.1 - 3e-19 70.2 0.0 6.5e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PRP89672.1 - 1.8e-14 53.2 0.0 4.7e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Sugar_tr PF00083.24 PRP89672.1 - 6.7e-10 38.4 38.1 1.5e-08 34.0 10.6 3.9 3 1 0 3 3 3 2 Sugar (and other) transporter Hydrolase_3 PF08282.12 PRP89672.1 - 0.00018 21.4 0.8 0.0006 19.6 0.2 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PRP89672.1 - 0.0064 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Lipoprotein_1 PF00820.19 PRP89672.1 - 0.14 11.2 0.4 0.25 10.4 0.4 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein Tn7_Tnp_TnsA_C PF08721.11 PRP89673.1 - 0.025 15.2 0.0 0.033 14.8 0.0 1.1 1 0 0 1 1 1 0 TnsA endonuclease C terminal E1-E2_ATPase PF00122.20 PRP89674.1 - 7.4e-54 182.0 2.0 7.4e-54 182.0 2.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PRP89674.1 - 2.1e-32 113.2 1.3 9.3e-32 111.0 0.1 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 PRP89674.1 - 1.2e-16 60.9 0.1 2.2e-09 37.6 0.1 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 PRP89674.1 - 0.00011 22.0 0.5 0.0064 16.3 0.2 2.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AsnC_trans_reg PF01037.21 PRP89674.1 - 0.018 15.0 0.0 0.073 13.0 0.0 2.1 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain BC10 PF06726.12 PRP89674.1 - 0.042 14.1 0.3 0.14 12.4 0.3 1.9 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 DUF2007 PF09413.10 PRP89674.1 - 0.045 13.9 2.0 2.7 8.2 0.0 3.4 3 1 0 3 3 3 0 Putative prokaryotic signal transducing protein Hydrolase_6 PF13344.6 PRP89674.1 - 0.073 13.2 0.2 0.34 11.1 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 PRP89674.1 - 0.17 12.3 0.1 0.68 10.3 0.1 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CBS PF00571.28 PRP89674.1 - 0.31 11.5 1.9 3.3 8.2 0.0 3.5 2 1 1 3 3 3 0 CBS domain DUF4519 PF15012.6 PRP89674.1 - 0.47 10.7 1.8 17 5.6 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) DUF4252 PF14060.6 PRP89674.1 - 1.7 8.5 4.3 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4252) LepA_C PF06421.12 PRP89674.1 - 8.9 6.5 7.1 2.4 8.4 2.2 2.4 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus LCAT PF02450.15 PRP89675.1 - 2.4e-05 23.7 0.0 4.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 PRP89675.1 - 6e-05 23.8 1.3 8.7e-05 23.2 0.4 1.7 1 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP89675.1 - 0.0093 15.3 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PRP89675.1 - 0.013 15.2 0.1 0.078 12.7 0.1 1.9 2 0 0 2 2 2 0 PGAP1-like protein COMM_domain PF07258.14 PRP89677.1 - 3.4e-17 62.3 0.7 7e-17 61.3 0.7 1.6 1 0 0 1 1 1 1 COMM domain SSF PF00474.17 PRP89677.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Sodium:solute symporter family MEA1 PF06910.11 PRP89678.1 - 0.00013 22.6 3.2 0.00037 21.1 3.2 1.8 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) Abi_HHR PF07815.14 PRP89679.1 - 0.016 15.4 0.1 0.042 14.0 0.0 1.7 2 0 0 2 2 2 0 Abl-interactor HHR SlyX PF04102.12 PRP89679.1 - 0.042 14.5 0.0 0.042 14.5 0.0 3.4 3 1 0 3 3 3 0 SlyX DUF2451 PF10474.9 PRP89679.1 - 0.072 12.9 0.5 0.099 12.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Ureidogly_lyase PF04115.12 PRP89680.1 - 2.4e-48 164.4 0.0 2.9e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase DUF4139 PF13598.6 PRP89681.1 - 0.0069 16.1 0.1 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) SAM_KSR1 PF13543.6 PRP89681.1 - 0.27 11.4 1.8 0.51 10.5 0.2 2.2 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 zf-RING_2 PF13639.6 PRP89682.1 - 3.9e-05 23.9 7.2 3.9e-05 23.9 7.2 2.5 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 PRP89682.1 - 0.00016 21.4 6.0 0.00016 21.4 6.0 2.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Borrelia_P83 PF05262.11 PRP89682.1 - 0.0013 17.3 11.0 0.0019 16.8 11.0 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein zf-RING_5 PF14634.6 PRP89682.1 - 0.0014 18.6 4.8 0.0014 18.6 4.8 2.7 2 1 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PRP89682.1 - 0.0014 18.2 3.7 0.0014 18.2 3.7 2.7 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 PRP89682.1 - 0.0021 17.7 5.1 0.0021 17.7 5.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PRP89682.1 - 0.0026 17.6 5.8 0.0026 17.6 5.8 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PRP89682.1 - 0.0072 16.6 4.3 0.0072 16.6 4.3 2.9 4 0 0 4 4 3 1 RING-H2 zinc finger domain zf-nanos PF05741.13 PRP89682.1 - 0.075 13.3 2.7 0.16 12.2 0.7 2.8 2 1 0 2 2 2 0 Nanos RNA binding domain zf-C3HC4_3 PF13920.6 PRP89682.1 - 0.14 12.0 11.3 0.21 11.5 4.6 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 PRP89682.1 - 0.19 11.6 0.2 0.19 11.6 0.2 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3H2C3 PF17122.5 PRP89682.1 - 0.32 11.1 8.7 0.17 11.9 5.7 2.3 2 1 0 2 2 1 0 Zinc-finger Prok-RING_4 PF14447.6 PRP89682.1 - 0.74 9.7 13.2 0.05 13.5 5.5 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PRP89682.1 - 0.8 9.8 5.7 2.8 8.1 5.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 PRP89682.1 - 0.84 9.7 6.2 0.11 12.5 1.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger SID-1_RNA_chan PF13965.6 PRP89682.1 - 2.1 6.6 4.1 2.9 6.2 4.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ubiquitin PF00240.23 PRP89683.1 - 3.6e-34 116.3 0.9 6.2e-34 115.6 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 PRP89683.1 - 2.5e-25 88.4 2.3 4.9e-25 87.4 2.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 PRP89683.1 - 5.9e-16 58.1 1.0 1.3e-15 57.0 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PRP89683.1 - 2.4e-05 24.7 0.2 9.5e-05 22.8 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PRP89683.1 - 0.00019 21.5 1.1 0.00042 20.4 1.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 PRP89683.1 - 0.00035 20.7 0.3 0.00068 19.8 0.3 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DUF2407 PF10302.9 PRP89683.1 - 0.0023 18.5 1.3 0.0043 17.6 1.2 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 PRP89683.1 - 0.0039 17.1 0.7 0.012 15.6 0.1 2.1 2 1 1 3 3 3 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PRP89683.1 - 0.014 15.7 1.8 0.014 15.7 0.2 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 PRP89683.1 - 0.042 13.9 1.2 7.6 6.7 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-like domain Ras PF00071.22 PRP89684.1 - 5.1e-53 179.0 0.0 6.5e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89684.1 - 1.4e-16 60.8 0.0 3.8e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89684.1 - 1.8e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PRP89684.1 - 0.009 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PRP89684.1 - 0.02 14.4 0.0 0.054 13.0 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PRP89684.1 - 0.033 14.1 0.0 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Pox_L5 PF04872.13 PRP89684.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Poxvirus L5 protein family Aminotran_1_2 PF00155.21 PRP89685.1 - 6.3e-30 104.6 0.0 8.5e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PRP89685.1 - 3.5e-10 39.7 0.0 5.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 PRP89685.1 - 6.7e-06 25.3 0.0 1.4e-05 24.2 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PRP89685.1 - 0.00078 18.1 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 PRP89685.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.7 3 0 0 3 3 3 0 Beta-eliminating lyase RVT_1 PF00078.27 PRP89688.1 - 3.1e-08 33.4 0.2 3.3e-05 23.5 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PigN PF04987.14 PRP89689.1 - 3.7e-89 299.7 44.1 1.7e-56 192.0 23.2 2.1 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 PRP89689.1 - 1e-13 51.7 0.0 7.2e-09 35.7 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PRP89689.1 - 1.5e-09 37.7 0.1 3.1e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 PRP89689.1 - 0.00021 20.7 0.0 0.00069 19.1 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Snf7 PF03357.21 PRP89690.1 - 6.5e-16 58.4 19.3 1e-15 57.8 19.3 1.3 1 0 0 1 1 1 1 Snf7 LMBR1 PF04791.16 PRP89691.1 - 2.5e-55 188.3 16.6 2.8e-52 178.3 7.4 2.3 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF3959 PF13105.6 PRP89691.1 - 0.97 8.9 10.1 0.095 12.2 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) PAP2 PF01569.21 PRP89692.1 - 6.2e-07 29.3 2.1 6.2e-07 29.3 2.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily ACP_PD PF04336.12 PRP89692.1 - 0.13 12.7 2.5 2.6 8.5 0.0 3.3 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase G0-G1_switch_2 PF15103.6 PRP89692.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF5434 PF17502.2 PRP89692.1 - 1 9.3 5.5 2.9 7.9 1.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5434) DUF3188 PF11384.8 PRP89692.1 - 2.2 8.0 4.7 2.7 7.8 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) IGR PF09597.10 PRP89693.1 - 1e-09 38.3 0.0 2.4e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 IGR protein motif Lge1 PF11488.8 PRP89693.1 - 0.0061 16.7 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 F-box PF00646.33 PRP89694.1 - 0.022 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain ArfGap PF01412.18 PRP89695.1 - 8.5e-29 100.0 0.8 1.3e-28 99.5 0.8 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Guanylate_cyc PF00211.20 PRP89696.1 - 9e-11 41.7 0.0 2.4e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Serine_rich PF08824.10 PRP89696.1 - 1.9e-05 24.7 5.1 0.00083 19.4 0.2 3.6 4 0 0 4 4 3 1 Serine rich protein interaction domain GAS2 PF02187.17 PRP89696.1 - 0.00012 22.1 0.5 0.0003 20.8 0.1 1.9 2 0 0 2 2 1 1 Growth-Arrest-Specific Protein 2 Domain FPP PF05911.11 PRP89696.1 - 0.0031 15.8 3.3 0.0031 15.8 3.3 2.4 2 1 0 2 2 2 1 Filament-like plant protein, long coiled-coil Tropomyosin PF00261.20 PRP89696.1 - 0.0081 15.5 4.0 0.0081 15.5 4.0 2.5 2 1 1 3 3 3 1 Tropomyosin APG6_N PF17675.1 PRP89696.1 - 0.041 14.4 16.3 0.12 12.9 4.4 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Hydrolase_6 PF13344.6 PRP89696.1 - 0.085 13.0 0.8 0.24 11.5 0.2 2.1 2 0 0 2 2 1 0 Haloacid dehalogenase-like hydrolase GAS PF13851.6 PRP89696.1 - 0.1 12.0 20.8 0.35 10.2 5.7 3.5 2 2 1 3 3 3 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 PRP89696.1 - 0.27 11.3 11.8 0.098 12.7 1.9 2.6 2 0 0 2 2 2 0 Laminin Domain II PI3K_P85_iSH2 PF16454.5 PRP89696.1 - 0.58 9.7 11.8 0.61 9.7 5.2 3.0 2 2 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Phage_HK97_TLTM PF06120.11 PRP89696.1 - 0.67 9.1 9.1 0.093 11.9 0.5 2.2 2 0 0 2 2 2 0 Tail length tape measure protein Fez1 PF06818.15 PRP89696.1 - 0.76 10.2 13.8 0.18 12.2 0.5 2.5 2 1 0 2 2 2 0 Fez1 TBCA PF02970.16 PRP89696.1 - 1.3 9.4 5.7 0.17 12.2 0.6 2.2 2 0 0 2 2 2 0 Tubulin binding cofactor A DUF2018 PF09442.10 PRP89696.1 - 1.3 10.0 5.0 0.38 11.8 1.3 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF2018) FlaC_arch PF05377.11 PRP89696.1 - 1.7 9.1 5.9 38 4.8 0.1 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF2353 PF09789.9 PRP89696.1 - 1.8 7.9 16.8 1.9 7.8 8.3 2.8 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Spc7 PF08317.11 PRP89696.1 - 1.9 7.3 16.9 3.2 6.5 3.2 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein CCDC144C PF14915.6 PRP89696.1 - 2.9 6.9 18.4 3.2 6.8 3.7 2.5 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region AAA_13 PF13166.6 PRP89696.1 - 3.5 6.2 9.9 1 7.9 1.1 2.8 3 0 0 3 3 3 0 AAA domain TPR_19 PF14559.6 PRP89697.1 - 4e-05 24.0 4.1 2.1 8.9 0.0 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP89697.1 - 0.00019 20.9 1.2 0.00045 19.7 1.2 1.6 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 PRP89697.1 - 0.00022 21.4 1.1 0.00022 21.4 1.1 3.2 4 1 0 4 4 4 1 Tetratricopeptide repeat MRFAP1 PF15155.6 PRP89697.1 - 0.022 15.3 3.2 0.09 13.3 3.2 2.1 1 0 0 1 1 1 0 MORF4 family-associated protein1 DUF3856 PF12968.7 PRP89697.1 - 0.036 14.1 2.0 0.5 10.4 0.2 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 PRP89697.1 - 0.096 13.4 0.4 0.52 11.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 PRP89697.1 - 0.2 11.6 1.8 4.8 7.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 PRP89697.1 - 0.43 11.3 0.0 0.43 11.3 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PRP89697.1 - 3.2 8.1 12.1 2.6 8.4 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PRP89697.1 - 3.9 8.6 0.0 3.9 8.6 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat SURF2 PF05477.11 PRP89698.1 - 1.8e-28 99.8 3.4 1.8e-28 99.8 3.4 2.1 1 1 1 2 2 2 1 Surfeit locus protein 2 (SURF2) NPR1_interact PF15699.5 PRP89698.1 - 0.0081 16.8 16.0 0.017 15.7 16.0 1.6 1 1 0 1 1 1 1 NPR1 interacting DUF1743 PF08489.11 PRP89698.1 - 0.026 14.6 0.0 0.026 14.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) Gti1_Pac2 PF09729.9 PRP89698.1 - 1 9.4 6.9 1.5 8.8 6.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family CDC45 PF02724.14 PRP89698.1 - 1.7 6.8 14.9 1.8 6.8 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein HI0933_like PF03486.14 PRP89699.1 - 3.7e-91 305.9 0.0 5.6e-91 305.3 0.0 1.3 1 1 0 1 1 1 1 HI0933-like protein DAO PF01266.24 PRP89699.1 - 5.8e-14 52.4 0.5 2.6e-06 27.3 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PRP89699.1 - 1.3e-10 40.9 0.1 1.3e-08 34.3 0.0 2.8 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 PRP89699.1 - 1.3e-08 34.4 0.2 6.7e-05 22.3 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PRP89699.1 - 1.2e-07 31.3 0.2 0.0013 18.0 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PRP89699.1 - 1.3e-06 28.8 0.5 0.024 15.2 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PRP89699.1 - 4.5e-06 26.8 0.0 1.2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 PRP89699.1 - 4.7e-06 26.2 0.6 7.3e-06 25.6 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PRP89699.1 - 2.5e-05 23.7 0.0 6.5e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 PRP89699.1 - 0.00011 22.2 0.0 0.00036 20.5 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.22 PRP89699.1 - 0.00015 21.0 0.7 0.00056 19.1 0.5 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 PRP89699.1 - 0.00031 20.0 0.1 0.00069 18.9 0.2 1.5 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 PRP89699.1 - 0.002 17.5 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 PRP89699.1 - 0.0047 16.8 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 PRP89699.1 - 0.0063 15.9 0.0 0.07 12.4 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.14 PRP89699.1 - 0.023 14.3 0.1 0.035 13.7 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 PRP89699.1 - 0.036 13.1 0.4 2.5 7.1 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 PRP89699.1 - 0.052 13.2 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 PRP89699.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MORN PF02493.20 PRP89700.1 - 2.3e-41 137.2 54.1 3e-08 33.1 1.6 8.2 8 0 0 8 8 8 7 MORN repeat SNARE PF05739.19 PRP89700.1 - 1.4e-08 34.6 0.0 2.9e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 SNARE domain F-box-like PF12937.7 PRP89700.1 - 1.6e-08 34.3 0.3 3.2e-08 33.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP89700.1 - 1.2e-07 31.4 0.7 3.2e-07 30.1 0.7 1.7 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 PRP89700.1 - 0.00042 20.8 0.2 0.0011 19.4 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A PRANC PF09372.10 PRP89700.1 - 0.021 15.1 0.0 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 PRANC domain Ac76 PF05814.11 PRP89700.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) Sec20 PF03908.13 PRP89700.1 - 0.11 12.4 2.7 10 6.1 0.1 2.3 2 0 0 2 2 2 0 Sec20 Use1 PF09753.9 PRP89700.1 - 0.12 12.1 2.8 0.88 9.2 0.3 2.2 2 0 0 2 2 2 0 Membrane fusion protein Use1 Baculo_11_kDa PF06143.11 PRP89700.1 - 0.18 11.4 1.6 0.39 10.3 1.6 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family TolA_bind_tri PF16331.5 PRP89700.1 - 8.1 6.6 8.0 1.3 9.1 2.2 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation SGT1 PF07093.11 PRP89701.1 - 7.1e-72 242.7 14.4 6.7e-67 226.3 0.5 3.0 1 1 2 3 3 3 3 SGT1 protein NDUF_B6 PF09782.9 PRP89701.1 - 0.025 14.7 0.4 0.54 10.4 0.1 2.3 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Sigma70_ner PF04546.13 PRP89701.1 - 0.59 10.0 4.5 1 9.2 4.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BTB PF00651.31 PRP89702.1 - 2.3e-17 63.2 0.0 1.5e-16 60.6 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 PRP89702.1 - 1.4e-09 38.0 0.3 1.8e-08 34.4 0.2 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 PRP89702.1 - 0.0026 17.9 2.4 0.046 13.8 2.4 2.3 1 1 0 1 1 1 1 F5/8 type C domain BTB_2 PF02214.22 PRP89702.1 - 0.022 15.1 0.0 0.069 13.5 0.0 1.9 1 0 0 1 1 1 0 BTB/POZ domain Rad60-SLD PF11976.8 PRP89703.1 - 7.7e-14 51.3 0.1 2.7e-07 30.3 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PRP89703.1 - 0.0021 17.8 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin family F-box-like PF12937.7 PRP89703.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like FAM76 PF16046.5 PRP89703.1 - 1.2 8.4 10.3 2.1 7.6 10.3 1.3 1 0 0 1 1 1 0 FAM76 protein Proteasom_Rpn13 PF04683.13 PRP89704.1 - 3e-26 91.8 0.0 6.2e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 PRP89704.1 - 5.1e-19 68.5 1.0 1.2e-18 67.3 0.6 1.8 1 1 0 1 1 1 1 UCH-binding domain Guanylate_cyc PF00211.20 PRP89705.1 - 1.8e-20 73.3 0.0 3.1e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain TPR_12 PF13424.6 PRP89705.1 - 3.4e-14 52.9 15.9 1.3e-05 25.4 0.4 6.4 5 2 2 7 7 7 3 Tetratricopeptide repeat AAA_16 PF13191.6 PRP89705.1 - 1.2e-09 38.8 0.0 3.9e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TPR_7 PF13176.6 PRP89705.1 - 9.1e-08 31.6 1.0 0.06 13.4 0.0 5.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 PRP89705.1 - 3.7e-05 23.3 0.1 0.00023 20.6 0.0 2.1 2 0 0 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 PRP89705.1 - 4.9e-05 23.1 3.1 0.17 11.8 0.4 4.4 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_22 PF13401.6 PRP89705.1 - 6.6e-05 23.2 0.0 0.00023 21.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_8 PF13181.6 PRP89705.1 - 0.00015 21.7 16.1 0.026 14.7 0.1 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 PRP89705.1 - 0.00054 19.7 12.4 2.6 8.0 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 PRP89705.1 - 0.003 17.5 17.3 0.097 12.8 0.3 7.2 7 1 1 8 8 7 1 Tetratricopeptide repeat NACHT PF05729.12 PRP89705.1 - 0.0045 16.9 0.0 0.014 15.3 0.0 2.0 1 0 0 1 1 1 1 NACHT domain SNAP PF14938.6 PRP89705.1 - 0.026 14.0 0.3 0.079 12.4 0.3 1.8 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 PRP89705.1 - 0.042 14.7 4.2 3.8 8.6 0.5 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DSPc PF00782.20 PRP89706.1 - 6.5e-23 81.0 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PRP89706.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 PRP89706.1 - 0.018 14.7 0.2 0.06 13.0 0.2 1.9 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 PRP89706.1 - 0.046 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Gelsolin PF00626.22 PRP89706.1 - 0.094 12.6 2.4 0.22 11.4 0.1 2.6 3 0 0 3 3 3 0 Gelsolin repeat Dishevelled PF02377.15 PRP89706.1 - 0.11 12.9 1.7 0.21 12.1 1.7 1.4 1 0 0 1 1 1 0 Dishevelled specific domain Init_tRNA_PT PF04179.12 PRP89706.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain VPS9 PF02204.18 PRP89707.1 - 2.2e-17 63.2 0.3 3.4e-17 62.6 0.3 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain alpha-hel2 PF14456.6 PRP89708.1 - 0.035 13.4 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 GLTSCR1 PF15249.6 PRP89708.1 - 0.061 13.8 2.6 0.14 12.7 2.6 1.5 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein DUF2890 PF11081.8 PRP89708.1 - 0.78 9.8 6.9 0.71 10.0 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Ax_dynein_light PF10211.9 PRP89709.1 - 4e-08 33.4 9.5 4e-08 33.4 9.5 2.5 1 1 1 2 2 2 1 Axonemal dynein light chain LMBR1 PF04791.16 PRP89709.1 - 5 5.9 7.3 7.3 5.4 7.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA PF00004.29 PRP89710.1 - 5.9e-40 136.7 0.0 1e-39 136.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PRP89710.1 - 4e-11 42.5 0.0 7.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 PRP89710.1 - 4.5e-05 23.3 0.0 8.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PRP89710.1 - 0.00011 22.4 0.4 0.0019 18.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PRP89710.1 - 0.00014 21.9 0.0 0.00038 20.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 PRP89710.1 - 0.00029 20.6 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 PRP89710.1 - 0.00065 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 PRP89710.1 - 0.00065 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 PRP89710.1 - 0.00079 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 PRP89710.1 - 0.00082 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PRP89710.1 - 0.00089 19.7 0.0 0.0023 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 PRP89710.1 - 0.0009 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PRP89710.1 - 0.0029 17.3 0.0 1.9 8.1 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 PRP89710.1 - 0.0075 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 PRP89710.1 - 0.0075 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PRP89710.1 - 0.0096 16.5 0.5 0.027 15.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 PRP89710.1 - 0.02 14.8 0.1 0.26 11.2 0.1 2.5 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 PRP89710.1 - 0.025 15.0 0.0 0.055 13.9 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 PRP89710.1 - 0.027 14.0 0.3 0.18 11.3 0.2 2.2 1 1 1 2 2 2 0 AAA domain LisH PF08513.11 PRP89710.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 LisH TsaE PF02367.17 PRP89710.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PRP89710.1 - 0.08 13.2 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 PRP89710.1 - 0.12 11.7 0.2 6 6.1 0.1 2.2 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 PRP89710.1 - 0.13 11.7 0.1 0.23 10.9 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Mon2_C PF16206.5 PRP89711.1 - 4.3e-64 217.0 7.4 9.9e-47 159.6 0.0 5.3 3 3 2 5 5 5 2 C-terminal region of Mon2 protein DCB PF16213.5 PRP89711.1 - 1e-43 149.0 2.8 1e-43 149.0 2.8 3.8 3 1 1 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 PRP89711.1 - 7.6e-39 133.1 7.8 1.2e-38 132.5 2.8 3.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HEAT PF02985.22 PRP89711.1 - 2.9e-07 30.1 0.1 1.2 9.6 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat DUF1981 PF09324.10 PRP89711.1 - 3.7e-07 29.9 5.3 7.9e-06 25.6 0.2 4.4 4 1 0 4 4 4 1 Domain of unknown function (DUF1981) Vac14_Fab1_bd PF12755.7 PRP89711.1 - 0.0077 16.8 0.4 0.59 10.8 0.1 3.5 2 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 PRP89711.1 - 0.092 13.1 0.0 1.1e+02 3.3 0.0 4.5 5 0 0 5 5 5 0 HEAT repeats Symplekin_C PF12295.8 PRP89711.1 - 0.16 12.1 3.3 0.3 11.2 0.3 3.0 2 1 0 2 2 2 0 Symplekin tight junction protein C terminal MMS22L_C PF14911.6 PRP89711.1 - 0.31 10.1 4.2 0.42 9.6 0.1 2.6 3 0 0 3 3 3 0 S-phase genomic integrity recombination mediator, C-terminal PCI PF01399.27 PRP89712.1 - 2.6e-16 60.0 0.6 8e-16 58.5 0.2 2.1 2 0 0 2 2 2 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 PRP89712.1 - 0.002 18.3 0.0 0.0047 17.0 0.0 1.6 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain Pkinase PF00069.25 PRP89714.1 - 3.5e-45 154.4 0.0 4.3e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89714.1 - 2.6e-27 95.7 0.0 3.5e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP89714.1 - 0.0031 16.9 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 PRP89714.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family TMEM234 PF10639.9 PRP89714.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane family 234 OTU PF02338.19 PRP89715.1 - 1.3e-26 93.6 2.2 1.4e-26 93.4 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PRP89715.1 - 1.3e-07 31.3 1.9 0.00029 20.4 0.0 3.2 2 1 1 3 3 3 2 Peptidase C65 Otubain MscS_TM PF12794.7 PRP89715.1 - 0.25 10.2 2.4 0.58 9.0 2.4 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 YL1 PF05764.13 PRP89715.1 - 1.9 8.5 38.2 2.7 8.1 38.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nnf1 PF03980.14 PRP89716.1 - 4.6e-06 27.0 7.6 6.4e-06 26.5 6.8 1.6 1 1 0 1 1 1 1 Nnf1 DUF4600 PF15372.6 PRP89716.1 - 0.29 11.6 8.8 0.62 10.5 8.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) RHH_7 PF16777.5 PRP89717.1 - 0.13 12.7 1.3 13 6.3 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulator, RHH-like, CopG TBPIP PF07106.13 PRP89718.1 - 8.8e-21 73.6 0.2 2.5e-20 72.1 0.2 1.8 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 PRP89718.1 - 5.2e-07 29.7 3.2 5.2e-07 29.7 3.2 2.2 3 0 0 3 3 3 1 Leucine zipper with capping helix domain NPV_P10 PF05531.12 PRP89718.1 - 0.03 14.8 3.7 0.31 11.5 3.7 2.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Mnd1 PF03962.15 PRP89718.1 - 0.075 13.3 0.1 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Mnd1 HTH domain FlaC_arch PF05377.11 PRP89718.1 - 0.25 11.7 3.3 0.57 10.6 0.8 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Syntaxin PF00804.25 PRP89718.1 - 0.56 9.8 7.6 0.26 10.9 3.2 2.2 2 1 0 2 2 2 0 Syntaxin V_ATPase_I PF01496.19 PRP89718.1 - 2.3 6.0 6.2 2.7 5.8 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LAG1-DNAbind PF09271.11 PRP89719.1 - 0.16 12.6 0.6 0.3 11.7 0.0 1.7 2 0 0 2 2 2 0 LAG1, DNA binding Diphthamide_syn PF01866.17 PRP89720.1 - 8.3e-93 311.1 0.0 1.3e-92 310.6 0.0 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein zf-B_box PF00643.24 PRP89721.1 - 0.00017 21.7 2.6 0.00025 21.1 2.6 1.3 1 0 0 1 1 1 1 B-box zinc finger Vfa1 PF08432.10 PRP89721.1 - 0.75 10.1 18.1 0.42 10.9 10.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Cwf_Cwc_15 PF04889.12 PRP89721.1 - 8.9 6.0 25.2 0.42 10.3 7.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein EF-hand_1 PF00036.32 PRP89722.1 - 4.3e-42 138.5 12.4 5.5e-10 38.1 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PRP89722.1 - 2.5e-36 123.9 3.0 1.6e-18 66.9 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PRP89722.1 - 1.1e-32 111.6 11.3 4.9e-15 55.1 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 PRP89722.1 - 4.7e-31 104.0 7.4 2e-09 36.6 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PRP89722.1 - 9.1e-28 94.5 9.5 1.5e-06 27.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 PRP89722.1 - 2.9e-15 56.3 0.1 5.4e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PRP89722.1 - 1.7e-10 40.7 0.8 2.3e-05 24.3 0.2 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PRP89722.1 - 8.9e-08 32.5 0.0 0.0015 18.8 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 PRP89722.1 - 6e-06 26.2 0.0 0.045 13.8 0.0 2.8 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 PRP89722.1 - 1.2e-05 25.4 4.6 0.02 15.1 0.4 3.2 1 1 3 4 4 4 2 Dockerin type I domain EF-hand_11 PF08976.11 PRP89722.1 - 3e-05 24.8 0.0 0.0026 18.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 PRP89722.1 - 0.00022 21.2 0.4 0.51 10.3 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.10 PRP89722.1 - 0.0004 20.4 1.0 0.001 19.1 0.1 2.1 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF3349 PF11829.8 PRP89722.1 - 0.00042 21.0 0.4 1.1 10.1 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF1103 PF06513.11 PRP89722.1 - 0.00085 19.0 1.8 0.0011 18.7 1.8 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.13 PRP89722.1 - 0.00099 19.1 0.7 0.57 10.1 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 PRP89722.1 - 0.0043 17.4 0.6 1.6 9.1 0.1 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb4 Poly_export PF02563.16 PRP89722.1 - 0.0044 17.2 0.1 0.32 11.2 0.0 2.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein EcoR124_C PF12008.8 PRP89722.1 - 0.018 14.7 0.6 0.029 14.0 0.5 1.4 1 1 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal SurA_N_2 PF13623.6 PRP89722.1 - 0.019 14.9 1.0 0.58 10.0 0.2 2.3 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 PRP89722.1 - 0.022 13.3 0.0 0.024 13.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) DUF4497 PF14924.6 PRP89722.1 - 0.032 14.7 0.0 4.3 7.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 PRP89722.1 - 0.047 14.1 0.1 15 6.2 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 PRP89722.1 - 0.052 12.7 0.1 1.8 7.6 0.0 2.2 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 PRP89722.1 - 0.072 13.2 0.1 0.22 11.7 0.1 1.9 1 1 0 2 2 2 0 Transcription factor MotA, activation domain EF-hand_14 PF17959.1 PRP89722.1 - 0.08 13.3 0.3 18 5.8 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain RloB PF13707.6 PRP89722.1 - 0.11 12.7 1.0 3.3 7.9 1.0 2.3 1 1 0 1 1 1 0 RloB-like protein SapB_1 PF05184.15 PRP89722.1 - 0.35 11.0 3.1 24 5.0 0.1 3.3 4 0 0 4 4 4 0 Saposin-like type B, region 1 PAP_PilO PF06864.12 PRP89723.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Cript PF10235.9 PRP89724.1 - 3e-24 85.4 8.5 4.2e-24 84.9 8.5 1.2 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT PLATZ PF04640.14 PRP89724.1 - 0.0051 17.4 2.8 0.025 15.2 0.7 2.2 1 1 1 2 2 2 1 PLATZ transcription factor zf-dskA_traR PF01258.17 PRP89724.1 - 0.017 15.0 4.7 0.11 12.5 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Sar8_2 PF03058.14 PRP89724.1 - 0.017 15.6 3.7 0.027 15.0 3.7 1.4 1 0 0 1 1 1 0 Sar8.2 family DUF1272 PF06906.11 PRP89724.1 - 0.034 14.2 2.3 0.034 14.2 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc_ribbon_15 PF17032.5 PRP89724.1 - 0.31 11.8 10.0 0.74 10.6 6.6 2.6 2 1 0 2 2 2 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 PRP89724.1 - 0.67 9.8 0.0 0.67 9.8 0.0 3.4 3 2 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 PRP89724.1 - 1.8 8.6 14.7 25 5.0 10.9 2.7 1 1 1 2 2 2 0 Double zinc ribbon zf_UBZ PF18439.1 PRP89724.1 - 3.3 7.4 0.0 3.3 7.4 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Carb_bind PF10645.9 PRP89726.1 - 2.6e-06 27.5 24.3 2.8e-05 24.3 11.5 6.0 4 1 1 5 5 5 3 Carbohydrate binding RMF PF04957.12 PRP89726.1 - 0.00064 19.9 20.6 1.3 9.2 0.1 5.1 5 0 0 5 5 5 4 Ribosome modulation factor DUF924 PF06041.11 PRP89727.1 - 1.1e-38 133.1 0.1 2.1e-38 132.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) FSH1 PF03959.13 PRP89727.1 - 4.8e-36 124.4 0.0 1.1e-35 123.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LRR_6 PF13516.6 PRP89727.1 - 8.7e-13 47.2 7.8 0.025 14.6 0.7 7.1 6 0 0 6 6 6 3 Leucine Rich repeat DUF2828 PF11443.8 PRP89727.1 - 6.7e-06 24.5 0.0 1.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Telomerase_RBD PF12009.8 PRP89728.1 - 3.6e-34 117.7 3.9 1.3e-33 115.9 3.4 2.4 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 PRP89728.1 - 9.6e-11 41.6 3.2 0.00091 18.8 0.0 5.4 5 0 0 5 5 5 4 Reverse transcriptase (RNA-dependent DNA polymerase) Clat_adaptor_s PF01217.20 PRP89729.1 - 4e-21 75.4 3.7 3e-20 72.6 3.7 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF4588 PF15251.6 PRP89730.1 - 7.5e-08 32.4 5.7 1.5e-06 28.2 5.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Psu PF07455.11 PRP89730.1 - 0.017 14.7 0.4 0.024 14.2 0.4 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) HemX PF04375.14 PRP89730.1 - 0.095 12.0 3.8 0.047 13.0 1.8 1.4 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CCDC53 PF10152.9 PRP89731.1 - 1.1e-37 129.8 12.1 8.3e-37 127.0 0.0 2.9 2 1 0 2 2 2 1 Subunit CCDC53 of WASH complex ArfGap PF01412.18 PRP89732.1 - 4.1e-35 120.4 0.6 1.3e-34 118.8 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 PRP89732.1 - 4.7e-06 27.1 0.3 1.6e-05 25.4 0.3 2.0 1 0 0 1 1 1 1 PH domain GST_N_3 PF13417.6 PRP89732.1 - 2.2e-05 24.8 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PRP89732.1 - 0.004 17.3 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PRP89732.1 - 0.0052 16.8 0.0 0.019 14.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PH_2 PF08458.10 PRP89732.1 - 0.0059 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Plant pleckstrin homology-like region GST_C PF00043.25 PRP89732.1 - 0.033 14.4 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AT_hook PF02178.19 PRP89732.1 - 0.074 13.0 4.1 0.42 10.6 4.1 2.4 1 0 0 1 1 1 0 AT hook motif zf-UBP PF02148.19 PRP89734.1 - 3.4e-18 65.7 4.6 1e-17 64.2 4.6 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 PRP89734.1 - 9.7e-10 38.6 0.0 2.9e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1-associated protein 2 CENP-H PF05837.12 PRP89734.1 - 8.7 6.8 10.3 22 5.5 10.3 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) EamA PF00892.20 PRP89735.1 - 7.5e-18 65.0 29.0 1.4e-11 44.7 5.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF1413 PF07205.11 PRP89735.1 - 0.36 10.9 1.1 2 8.5 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1413) Phospholip_A2_3 PF09056.11 PRP89736.1 - 0.089 13.4 0.9 6.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic phospholipase A2 DUF2089 PF09862.9 PRP89736.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) RD3 PF14473.6 PRP89736.1 - 0.22 11.4 0.1 0.22 11.4 0.1 1.6 2 0 0 2 2 2 0 RD3 protein Pkinase PF00069.25 PRP89737.1 - 4.9e-61 206.4 0.0 1.5e-60 204.8 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain RSN1_7TM PF02714.15 PRP89737.1 - 7.3e-59 199.3 25.2 1.5e-58 198.3 25.2 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Pkinase_Tyr PF07714.17 PRP89737.1 - 4.5e-33 114.6 0.0 9.6e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RSN1_TM PF13967.6 PRP89737.1 - 1.2e-30 106.3 2.6 6.1e-30 104.0 2.6 2.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PRP89737.1 - 2.6e-13 50.6 0.0 2.6e-13 50.6 0.0 4.9 3 2 0 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter APG17 PF04108.12 PRP89737.1 - 0.0024 17.1 7.7 0.0024 17.1 7.7 3.9 3 1 0 3 3 3 2 Autophagy protein Apg17 YrbL-PhoP_reg PF10707.9 PRP89737.1 - 0.013 15.0 0.0 0.059 12.9 0.0 2.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 PRP89737.1 - 0.013 15.4 0.0 0.056 13.4 0.0 2.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 PRP89737.1 - 0.016 15.4 2.7 0.028 14.6 0.0 2.7 2 0 0 2 2 2 0 ABC1 family BORCS7 PF16088.5 PRP89737.1 - 0.066 13.5 0.1 0.066 13.5 0.1 2.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Bac_rhodopsin PF01036.18 PRP89738.1 - 1.4e-19 70.6 15.5 1.8e-19 70.2 15.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1772 PF08592.11 PRP89738.1 - 0.59 10.4 13.0 0.26 11.6 0.5 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) EamA PF00892.20 PRP89738.1 - 1.5 9.0 14.9 0.14 12.3 6.8 2.3 2 0 0 2 2 2 0 EamA-like transporter family ABC_tran PF00005.27 PRP89739.1 - 6.3e-39 133.6 10.3 6.4e-21 75.3 0.0 4.2 4 1 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 PRP89739.1 - 2.6e-14 53.7 10.3 0.0056 16.5 0.0 4.7 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PRP89739.1 - 2e-08 34.8 2.2 0.0038 17.6 0.0 3.4 4 1 0 4 4 2 2 AAA ATPase domain SMC_N PF02463.19 PRP89739.1 - 4.7e-08 32.7 2.5 0.00081 18.9 0.4 4.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PRP89739.1 - 1.6e-07 30.9 0.1 0.006 16.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 PRP89739.1 - 3.9e-07 30.5 4.1 0.79 10.1 0.1 4.9 4 1 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 PRP89739.1 - 6.4e-07 29.4 0.2 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 PRP89739.1 - 7.8e-06 25.9 2.7 0.019 14.9 0.1 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_15 PF13175.6 PRP89739.1 - 1.3e-05 25.1 15.2 0.011 15.5 0.0 4.4 4 1 1 5 5 5 2 AAA ATPase domain AAA_14 PF13173.6 PRP89739.1 - 1.6e-05 24.9 0.0 0.12 12.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 PRP89739.1 - 2.6e-05 24.0 0.1 0.0021 17.8 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 PRP89739.1 - 3.7e-05 23.7 0.2 0.046 13.7 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 PRP89739.1 - 4.9e-05 23.6 0.8 0.6 10.4 0.0 3.7 4 0 0 4 4 2 2 AAA domain V-SNARE PF05008.15 PRP89739.1 - 5.6e-05 23.4 4.7 5.6e-05 23.4 4.7 3.2 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus AAA_18 PF13238.6 PRP89739.1 - 8.1e-05 23.2 2.9 0.32 11.5 0.0 4.0 3 1 1 4 4 2 2 AAA domain RNA_helicase PF00910.22 PRP89739.1 - 0.00021 21.7 0.3 2.1 8.8 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.6 PRP89739.1 - 0.00033 20.9 3.5 0.74 10.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain T2SSE PF00437.20 PRP89739.1 - 0.00044 19.4 0.7 0.023 13.8 0.0 3.0 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF3584 PF12128.8 PRP89739.1 - 0.0006 17.5 32.7 0.16 9.5 13.2 4.1 3 1 1 4 4 4 3 Protein of unknown function (DUF3584) ATP-synt_ab PF00006.25 PRP89739.1 - 0.00067 19.4 0.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 PRP89739.1 - 0.0008 19.2 0.0 1.6 8.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 PRP89739.1 - 0.00093 19.7 27.2 0.051 14.1 0.0 4.6 3 2 0 3 3 2 2 AAA domain DAP3 PF10236.9 PRP89739.1 - 0.0015 17.8 0.1 0.23 10.6 0.0 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_27 PF13514.6 PRP89739.1 - 0.0015 18.2 0.0 0.34 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PRP89739.1 - 0.0017 18.4 0.1 2.7 8.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PRP89739.1 - 0.0018 18.4 0.1 0.76 9.9 0.0 3.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 PRP89739.1 - 0.002 17.3 0.3 2.1 7.5 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain Mg_chelatase PF01078.21 PRP89739.1 - 0.0034 16.8 0.0 0.77 9.1 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 PRP89739.1 - 0.004 16.9 0.1 5.8 6.7 0.0 3.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 PRP89739.1 - 0.0063 16.3 0.1 0.3 10.8 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 PRP89739.1 - 0.0067 16.4 0.5 6.8 6.6 0.1 3.1 3 0 0 3 3 2 0 NTPase ATPase_2 PF01637.18 PRP89739.1 - 0.0073 16.2 1.5 0.7 9.8 0.0 3.1 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 PRP89739.1 - 0.011 15.0 0.1 3.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin SRPRB PF09439.10 PRP89739.1 - 0.012 15.1 0.0 0.2 11.1 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PRP89739.1 - 0.015 15.4 2.5 1.3 9.1 0.1 3.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase Roc PF08477.13 PRP89739.1 - 0.016 15.4 0.2 0.36 11.1 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 PRP89739.1 - 0.021 14.3 0.0 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 PRP89739.1 - 0.024 14.2 0.0 4.8 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PRP89739.1 - 0.031 14.3 0.1 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 PRP89739.1 - 0.034 13.9 0.4 2.7 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain V-SNARE_C PF12352.8 PRP89739.1 - 0.036 14.3 1.4 0.14 12.5 1.4 2.1 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus FtsK_SpoIIIE PF01580.18 PRP89739.1 - 0.049 13.0 0.0 7.3 5.9 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sec20 PF03908.13 PRP89739.1 - 0.089 12.7 2.0 0.88 9.5 0.3 2.9 2 0 0 2 2 2 0 Sec20 Ribosomal_S10 PF00338.22 PRP89739.1 - 0.089 13.0 0.7 0.7 10.2 0.2 2.6 2 0 0 2 2 2 0 Ribosomal protein S10p/S20e KxDL PF10241.9 PRP89739.1 - 0.11 12.7 0.1 0.11 12.7 0.1 4.3 4 1 1 5 5 3 0 Uncharacterized conserved protein dNK PF01712.19 PRP89739.1 - 0.12 12.2 1.8 13 5.6 0.0 3.1 3 0 0 3 3 2 0 Deoxynucleoside kinase BORCS8 PF10167.9 PRP89739.1 - 0.14 12.1 1.5 0.25 11.3 0.1 2.2 2 1 0 2 2 1 0 BLOC-1-related complex sub-unit 8 DUF2813 PF11398.8 PRP89739.1 - 0.19 11.0 6.1 0.68 9.1 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2813) TolA_bind_tri PF16331.5 PRP89739.1 - 0.42 10.7 7.3 12 6.1 0.4 3.7 2 1 1 3 3 3 0 TolA binding protein trimerisation SNARE PF05739.19 PRP89739.1 - 0.65 10.0 5.2 2 8.4 5.2 1.9 1 1 0 1 1 1 0 SNARE domain DUF1664 PF07889.12 PRP89739.1 - 0.73 9.9 11.2 6.7 6.8 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TBCC_N PF16752.5 PRP89739.1 - 0.77 10.2 13.5 1.5 9.3 0.7 4.1 2 1 1 4 4 4 0 Tubulin-specific chaperone C N-terminal domain PT PF04886.12 PRP89740.1 - 5.5e-05 22.6 70.0 0.0046 16.5 3.3 10.1 5 4 0 5 5 5 3 PT repeat GST_N_2 PF13409.6 PRP89741.1 - 3.8e-17 62.3 0.0 4.5e-16 58.9 0.0 2.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Macro PF01661.21 PRP89741.1 - 4.8e-11 42.7 0.0 7.7e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Macro domain Macro_2 PF14519.6 PRP89741.1 - 8.5e-08 31.9 0.0 2.6e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Macro-like domain GST_N_3 PF13417.6 PRP89741.1 - 0.0043 17.4 0.0 1.3 9.5 0.0 2.9 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Pkinase_Tyr PF07714.17 PRP89743.1 - 4.8e-82 275.1 0.0 1.3e-81 273.7 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89743.1 - 5.5e-49 166.9 0.0 4.2e-48 164.0 0.0 2.7 1 0 0 1 1 1 1 Protein kinase domain Gelsolin PF00626.22 PRP89743.1 - 3.8e-20 71.6 11.6 2e-07 30.8 0.0 5.7 5 0 0 5 5 5 3 Gelsolin repeat C2 PF00168.30 PRP89743.1 - 2.3e-11 43.9 0.0 6.1e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain FERM_N PF09379.10 PRP89743.1 - 0.00071 19.5 0.1 0.76 9.8 0.1 2.8 2 0 0 2 2 2 2 FERM N-terminal domain CHU_C PF13585.6 PRP89743.1 - 0.017 15.1 2.4 0.054 13.5 0.1 2.9 2 0 0 2 2 2 0 C-terminal domain of CHU protein family Cornifin PF02389.15 PRP89743.1 - 0.28 11.4 31.9 0.24 11.6 9.3 3.6 1 1 2 3 3 3 0 Cornifin (SPRR) family RRM_1 PF00076.22 PRP89744.1 - 6.9e-34 115.5 0.0 9.3e-17 60.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PRP89744.1 - 0.00072 19.6 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 PRP89744.1 - 0.00078 19.1 0.7 1.3 8.8 0.2 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 PRP89744.1 - 0.00096 18.7 0.0 0.0019 17.8 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tombus_P19 PF03220.13 PRP89744.1 - 0.032 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Tombusvirus P19 core protein F-box-like PF12937.7 PRP89745.1 - 1.4e-07 31.3 0.8 2.6e-07 30.4 0.8 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP89745.1 - 3.6e-07 29.9 0.5 6.5e-07 29.1 0.5 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 PRP89745.1 - 0.0076 16.1 0.3 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 F-box SASA PF03629.18 PRP89746.1 - 1.2e-15 57.8 0.0 4.9e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Citrate_synt PF00285.21 PRP89748.1 - 8.3e-138 459.3 0.0 1.1e-137 459.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Invasin_D3 PF09134.10 PRP89748.1 - 0.067 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Invasin, domain 3 Golgin_A5 PF09787.9 PRP89749.1 - 4.8e-57 193.7 38.0 4.8e-57 193.7 38.0 3.6 2 1 2 4 4 4 1 Golgin subfamily A member 5 F-box-like PF12937.7 PRP89749.1 - 0.0082 16.0 0.5 0.0082 16.0 0.5 2.1 2 0 0 2 2 2 1 F-box-like CRISPR_Cas2 PF09827.9 PRP89749.1 - 0.042 14.0 2.6 0.066 13.4 0.3 2.6 2 0 0 2 2 2 0 CRISPR associated protein Cas2 F-box PF00646.33 PRP89749.1 - 0.54 10.2 5.1 0.42 10.6 0.6 2.7 2 1 0 2 2 2 0 F-box domain SET PF00856.28 PRP89749.1 - 0.65 10.4 0.0 0.65 10.4 0.0 5.2 3 2 0 3 3 3 0 SET domain SelB-wing_1 PF09105.10 PRP89749.1 - 1.6 8.7 6.1 3.2 7.8 0.4 2.9 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Fer2_3 PF13085.6 PRP89750.1 - 6e-30 103.5 0.0 9.5e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_8 PF13183.6 PRP89750.1 - 1.1e-09 38.6 10.1 1.5e-09 38.1 7.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 PRP89750.1 - 5.9e-09 36.3 4.7 5.9e-09 36.3 4.7 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 PRP89750.1 - 4.4e-07 29.9 3.2 4.4e-07 29.9 3.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 PRP89750.1 - 0.0013 18.9 0.9 0.36 11.1 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 PRP89750.1 - 0.0054 17.3 10.1 0.32 11.6 11.4 2.7 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 PRP89750.1 - 0.027 14.4 0.5 0.027 14.4 0.5 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 PRP89750.1 - 0.34 11.1 15.7 1.3 9.3 11.0 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain Calpain_III PF01067.22 PRP89751.1 - 4.4e-41 140.4 0.0 3.7e-12 46.7 0.0 3.8 3 0 0 3 3 3 3 Calpain large subunit, domain III C2 PF00168.30 PRP89751.1 - 2.8e-07 30.8 2.9 7.7e-07 29.4 0.2 3.1 3 1 0 3 3 3 1 C2 domain Melibiase_2 PF16499.5 PRP89753.1 - 2.6e-67 227.0 7.6 2.1e-56 191.2 6.6 2.3 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 PRP89753.1 - 4.4e-08 33.1 0.3 2.6e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 PRP89753.1 - 1.2e-05 24.5 0.2 2.4e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Melibiase Glyco_hydro_97 PF10566.9 PRP89753.1 - 0.00014 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 97 Ras PF00071.22 PRP89754.1 - 1.5e-07 31.1 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89754.1 - 0.035 14.3 0.0 0.1 12.9 0.0 1.7 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_5 PF13857.6 PRP89756.1 - 8.3e-14 51.5 0.5 1.6e-08 34.6 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP89756.1 - 5.4e-13 49.3 0.1 5.3e-12 46.1 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP89756.1 - 2e-12 47.4 0.0 2.5e-06 27.9 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PRP89756.1 - 9.8e-11 41.6 0.0 0.0055 17.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 PRP89756.1 - 1.7e-07 31.0 0.0 0.73 10.6 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat UVR PF02151.19 PRP89756.1 - 2.4e-05 23.9 0.7 8.7e-05 22.1 0.7 2.0 1 0 0 1 1 1 1 UvrB/uvrC motif WRNPLPNID PF15017.6 PRP89756.1 - 1.8 9.5 4.6 0.57 11.1 0.4 2.2 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Acyltransferase PF01553.21 PRP89757.1 - 3e-19 69.0 0.1 1.6e-18 66.6 0.0 2.0 2 0 0 2 2 2 1 Acyltransferase FtsX PF02687.21 PRP89757.1 - 6.3 7.4 10.7 78 3.8 10.0 2.8 2 1 0 2 2 2 0 FtsX-like permease family ERCC4 PF02732.15 PRP89758.1 - 4.2e-07 30.3 0.6 1.8e-05 25.0 0.0 2.8 3 0 0 3 3 3 1 ERCC4 domain US30 PF17624.2 PRP89758.1 - 0.058 12.4 0.8 0.15 11.1 0.8 1.7 1 0 0 1 1 1 0 Family of unknown function tRNA_U5-meth_tr PF05958.11 PRP89758.1 - 0.22 10.5 0.1 0.41 9.6 0.1 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FAM70 PF14967.6 PRP89758.1 - 9 5.7 12.4 18 4.7 12.4 1.4 1 0 0 1 1 1 0 FAM70 protein RasGEF PF00617.19 PRP89759.1 - 5.8e-19 69.0 0.0 1.3e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain LRR_4 PF12799.7 PRP89759.1 - 1.7e-12 47.3 22.9 0.0017 18.7 0.0 7.9 5 2 5 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PRP89759.1 - 4.9e-11 42.2 17.8 0.017 14.8 2.1 6.3 3 1 4 7 7 7 7 Leucine rich repeat GPS PF01825.21 PRP89759.1 - 6.9e-11 42.5 3.7 2e-10 41.0 3.7 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP89759.1 - 5.1e-07 29.2 0.0 4.8e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89759.1 - 4.3e-06 26.3 0.0 2e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain TIG PF01833.24 PRP89759.1 - 0.00041 20.4 3.8 0.0024 17.9 2.0 3.2 2 0 0 2 2 2 1 IPT/TIG domain AP_endonuc_2 PF01261.24 PRP89760.1 - 9e-30 103.7 0.0 2e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF4252 PF14060.6 PRP89760.1 - 0.34 10.8 3.2 0.23 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) DDE_Tnp_1_7 PF13843.6 PRP89761.1 - 0.00032 20.1 0.0 0.002 17.5 0.0 2.0 1 1 0 1 1 1 1 Transposase IS4 DUF229 PF02995.17 PRP89762.1 - 9.7e-45 153.1 0.2 2e-44 152.0 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 PRP89762.1 - 0.031 13.7 1.5 0.85 8.9 1.5 2.5 1 1 0 1 1 1 0 Sulfatase Lipase_3 PF01764.25 PRP89764.1 - 1.8e-25 89.5 0.1 4e-25 88.3 0.1 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 PRP89764.1 - 0.054 12.7 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PurA PF04845.13 PRP89764.1 - 0.13 11.5 0.0 0.77 9.0 0.0 2.1 2 0 0 2 2 2 0 PurA ssDNA and RNA-binding protein DUF3439 PF11921.8 PRP89764.1 - 1.4 8.9 6.5 5.7 6.9 4.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Arf PF00025.21 PRP89765.1 - 2.3e-74 248.6 0.0 5.1e-74 247.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Pkinase_Tyr PF07714.17 PRP89765.1 - 9.4e-54 182.4 0.0 1.4e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89765.1 - 7.5e-47 159.9 0.0 1.1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GMC_oxred_N PF00732.19 PRP89765.1 - 4e-32 111.8 0.0 1e-31 110.5 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase Ctr PF04145.15 PRP89765.1 - 4.2e-30 105.3 0.1 1.3e-29 103.7 0.2 1.9 2 0 0 2 2 1 1 Ctr copper transporter family Ank_4 PF13637.6 PRP89765.1 - 6.4e-21 74.4 3.3 0.00012 22.6 0.1 5.2 3 1 2 5 5 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PRP89765.1 - 3.7e-18 65.9 3.4 1.8e-07 31.7 0.9 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 PRP89765.1 - 9e-18 63.9 2.6 6.3e-06 26.4 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat C2 PF00168.30 PRP89765.1 - 2.4e-17 63.1 0.0 7.1e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 C2 domain Ank_5 PF13857.6 PRP89765.1 - 6e-15 55.1 1.7 0.00045 20.5 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Roc PF08477.13 PRP89765.1 - 7.7e-13 48.7 0.0 2.1e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GMC_oxred_C PF05199.13 PRP89765.1 - 5.9e-12 46.3 0.0 1.3e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Ank_3 PF13606.6 PRP89765.1 - 5.1e-10 38.7 1.3 0.1 13.2 0.0 5.2 5 0 0 5 5 4 3 Ankyrin repeat Ras PF00071.22 PRP89765.1 - 7.2e-10 38.7 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PRP89765.1 - 3.8e-09 36.2 0.0 7.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PRP89765.1 - 1e-07 31.5 0.3 0.00012 21.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 PRP89765.1 - 1.1e-07 31.4 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Abhydrolase_1 PF00561.20 PRP89765.1 - 1.6e-05 24.7 0.1 7e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold SAM_1 PF00536.30 PRP89765.1 - 3.2e-05 24.3 0.1 8e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PRP89765.1 - 7e-05 22.9 0.1 0.00018 21.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydrolase_6 PF12697.7 PRP89765.1 - 0.00092 19.9 0.9 0.00092 19.9 0.9 2.2 2 0 0 2 2 1 1 Alpha/beta hydrolase family NAD_binding_8 PF13450.6 PRP89765.1 - 0.0035 17.5 0.0 0.042 14.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lipase_3 PF01764.25 PRP89765.1 - 0.0067 16.3 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 Lipase (class 3) MMR_HSR1 PF01926.23 PRP89765.1 - 0.016 15.3 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DAO PF01266.24 PRP89765.1 - 0.017 14.8 0.0 0.083 12.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Hydrolase_4 PF12146.8 PRP89765.1 - 0.045 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pyr_redox_2 PF07992.14 PRP89765.1 - 0.058 12.6 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PRP89765.1 - 0.07 11.8 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein MpPF26 PF07666.11 PRP89766.1 - 1.6 8.9 8.5 0.28 11.3 3.0 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 RRM_1 PF00076.22 PRP89767.1 - 1e-18 66.9 0.0 1.6e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 PRP89768.1 - 8.6e-51 171.7 0.0 1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PRP89768.1 - 2.2e-32 111.8 0.0 3.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PRP89768.1 - 4.4e-13 49.1 0.0 5.8e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PRP89768.1 - 5.4e-06 26.1 0.0 0.0022 17.5 0.0 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PRP89768.1 - 2.7e-05 24.2 0.0 4.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PRP89768.1 - 7.3e-05 22.2 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PRP89768.1 - 0.0044 16.9 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 PRP89768.1 - 0.009 16.3 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 PRP89768.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PRP89768.1 - 0.013 15.9 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 PRP89768.1 - 0.031 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 PRP89768.1 - 0.077 12.7 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 PRP89768.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 PRP89768.1 - 0.15 12.6 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Pkinase_Tyr PF07714.17 PRP89769.1 - 1.7e-55 188.1 0.0 2.8e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89769.1 - 6.2e-54 183.1 0.0 9.5e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PRP89769.1 - 0.00021 20.2 1.0 0.00029 19.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 PRP89769.1 - 0.0037 16.3 0.0 0.0037 16.3 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 PRP89769.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIP49_C PF12260.8 PRP89769.1 - 0.012 15.2 0.1 0.071 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 TFIIA PF03153.13 PRP89769.1 - 0.76 9.7 6.0 0.99 9.3 6.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit P16-Arc PF04699.14 PRP89770.1 - 0.061 13.8 0.0 0.068 13.7 0.0 1.1 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Acetyltransf_3 PF13302.7 PRP89771.1 - 5.2e-15 56.3 0.1 7.9e-15 55.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PRP89771.1 - 0.0013 18.9 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PRP89771.1 - 0.041 13.6 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PRP89771.1 - 0.048 13.9 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pkinase_Tyr PF07714.17 PRP89772.1 - 7.7e-43 146.6 0.0 1.4e-42 145.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89772.1 - 5.1e-28 98.2 0.0 7.4e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain GST_N_2 PF13409.6 PRP89772.1 - 0.029 14.6 0.0 0.11 12.9 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Kdo PF06293.14 PRP89772.1 - 0.053 12.9 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PRP89772.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like UvdE PF03851.14 PRP89775.1 - 4.4e-86 288.6 0.0 5.9e-86 288.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE Luciferase_cat PF10285.9 PRP89776.1 - 0.074 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Luciferase catalytic domain AAA_16 PF13191.6 PRP89777.1 - 1.3e-17 64.7 0.0 4.9e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Guanylate_cyc PF00211.20 PRP89777.1 - 8e-17 61.4 0.1 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain C2 PF00168.30 PRP89777.1 - 4.3e-12 46.2 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain ATPase_2 PF01637.18 PRP89777.1 - 0.00059 19.8 1.0 0.009 16.0 0.9 2.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 PRP89777.1 - 0.00085 19.6 0.2 0.025 14.8 0.2 2.6 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 PRP89777.1 - 0.0024 17.8 0.1 0.2 11.6 0.0 3.0 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 PRP89777.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 PRP89777.1 - 0.078 13.3 0.4 0.53 10.6 0.4 2.2 1 1 0 1 1 1 0 AAA domain TMEM237 PF15383.6 PRP89778.1 - 1e-13 51.0 0.1 1e-13 51.0 0.1 2.6 2 1 1 3 3 3 1 Transmembrane protein 237 SDA1 PF05285.12 PRP89778.1 - 0.0064 16.0 4.7 0.0064 16.0 4.7 2.1 2 0 0 2 2 2 2 SDA1 CDC45 PF02724.14 PRP89778.1 - 0.02 13.2 23.7 0.028 12.7 2.8 2.4 2 0 0 2 2 2 0 CDC45-like protein Neur_chan_memb PF02932.16 PRP89778.1 - 1.2 9.1 13.9 4.2 7.4 7.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.10 PRP89778.1 - 6.6 7.0 37.0 1.2 9.5 8.7 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Pkinase PF00069.25 PRP89779.1 - 3.9e-78 262.4 0.1 4.7e-78 262.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89779.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PRP89779.1 - 1.7e-07 30.8 0.0 1.4e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PRP89779.1 - 8.1e-07 28.1 0.3 5.4e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 PRP89779.1 - 6.8e-06 25.8 1.0 1.3e-05 24.9 1.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 PRP89779.1 - 2.9e-05 23.5 1.1 3e-05 23.5 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP89779.1 - 0.00081 19.4 0.0 0.085 12.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 PRP89779.1 - 0.001 18.7 0.2 0.0019 17.8 0.2 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 PRP89779.1 - 0.022 14.4 0.2 0.46 10.1 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RPN6_N PF18055.1 PRP89779.1 - 0.029 14.7 0.2 0.066 13.6 0.2 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain TTL PF03133.15 PRP89780.1 - 7.7e-53 179.5 0.0 1.1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PRP89780.1 - 0.00013 21.3 0.1 0.00039 19.7 0.0 1.8 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PRP89780.1 - 0.00044 19.6 0.0 0.043 13.1 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 PRP89780.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Dala_Dala_lig_C PF07478.13 PRP89780.1 - 0.11 12.0 0.0 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus zf-CCCH_4 PF18044.1 PRP89780.1 - 0.78 9.6 4.0 1.6 8.6 4.0 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger 6PGD PF00393.19 PRP89781.1 - 3.5e-127 423.8 0.0 5e-127 423.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 PRP89781.1 - 5e-49 166.5 0.0 7.9e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Cupin_8 PF13621.6 PRP89781.1 - 1.8e-17 63.9 1.2 4.3e-17 62.7 1.2 1.6 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PRP89781.1 - 7e-12 45.8 0.1 2.2e-11 44.2 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 PRP89781.1 - 2.4e-05 24.1 0.6 8e-05 22.5 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PRP89781.1 - 4.9e-05 23.1 1.7 4.9e-05 23.1 1.7 2.4 3 0 0 3 3 3 1 F-box domain Cupin_2 PF07883.11 PRP89781.1 - 0.0051 16.5 0.0 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Shikimate_DH PF01488.20 PRP89781.1 - 0.0091 16.1 0.2 0.023 14.8 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Cupin_4 PF08007.12 PRP89781.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein NAD_binding_11 PF14833.6 PRP89781.1 - 0.072 13.3 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NUDIX PF00293.28 PRP89782.1 - 7.2e-19 68.1 0.2 1.2e-18 67.5 0.2 1.3 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 PRP89784.1 - 1.5e-17 63.9 0.3 1.8e-12 47.2 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89784.1 - 1.6e-17 63.7 0.2 2.4e-11 43.4 0.1 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase GPS PF01825.21 PRP89784.1 - 0.0031 18.0 0.9 0.0031 18.0 0.9 2.0 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif DUF4083 PF13314.6 PRP89784.1 - 0.92 9.5 4.0 15 5.6 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Pkinase PF00069.25 PRP89785.1 - 5.9e-62 209.4 0.0 9.3e-62 208.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89785.1 - 1.1e-40 139.5 0.0 1.9e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 PRP89785.1 - 2.1e-40 137.2 1.4 1.1e-13 51.5 0.1 5.7 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PRP89785.1 - 1.9e-33 114.4 5.7 3.3e-12 46.6 0.0 7.8 2 2 8 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PRP89785.1 - 3.8e-33 109.8 2.1 0.00017 21.7 0.0 9.6 10 0 0 10 10 8 6 Ankyrin repeat Ank_5 PF13857.6 PRP89785.1 - 3.6e-29 100.5 10.2 1.2e-08 35.1 0.1 7.7 6 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 PRP89785.1 - 2.8e-27 93.9 0.7 0.00012 22.4 0.0 8.1 7 0 0 7 7 7 6 Ankyrin repeat Pkinase_fungal PF17667.1 PRP89785.1 - 4.7e-07 28.9 0.0 7.7e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PRP89785.1 - 8.3e-05 22.0 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Tmemb_cc2 PF10267.9 PRP89785.1 - 0.0039 16.4 0.2 0.0078 15.4 0.2 1.5 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein APH PF01636.23 PRP89785.1 - 0.0042 17.0 0.0 0.32 10.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PRP89785.1 - 0.046 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAA_hydro_N_2 PF18288.1 PRP89785.1 - 0.051 14.0 0.1 0.21 12.0 0.1 2.0 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 DUF1679 PF07914.11 PRP89785.1 - 0.056 12.3 0.0 0.46 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) P35 PF02331.15 PRP89785.1 - 0.07 12.5 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Apoptosis preventing protein Cep57_MT_bd PF06657.13 PRP89785.1 - 0.44 11.0 3.1 0.6 10.6 0.2 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Peptidase_C14 PF00656.22 PRP89786.1 - 5.1e-53 180.6 0.0 9.5e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Ferritin-like PF12902.7 PRP89786.1 - 4.4e-14 52.9 0.0 1.2e-13 51.5 0.0 1.7 1 1 0 1 1 1 1 Ferritin-like Ferritin-like PF12902.7 PRP89787.1 - 6.4e-12 45.8 2.2 6.4e-12 45.8 2.2 2.9 2 1 0 2 2 2 1 Ferritin-like Atrophin-1 PF03154.15 PRP89787.1 - 4.5 5.4 9.2 7.4 4.7 9.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family GPS PF01825.21 PRP89788.1 - 1.6e-10 41.3 5.8 4.7e-10 39.8 5.8 1.9 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Pkinase PF00069.25 PRP89788.1 - 3.9e-09 36.3 0.0 1.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89788.1 - 3.8e-07 29.7 0.0 2.4e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PRP89788.1 - 3e-06 26.9 7.9 3.2e-05 23.6 4.4 2.6 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PRP89788.1 - 4.3e-05 23.8 9.7 0.00076 19.8 1.2 3.2 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PRP89788.1 - 0.00088 19.5 0.1 0.0035 17.6 0.1 2.1 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PRP89788.1 - 0.87 10.4 8.2 1.1e+02 3.9 0.1 5.3 3 1 0 3 3 3 0 Leucine Rich Repeat GPS PF01825.21 PRP89789.1 - 1.3e-18 67.2 21.9 3.9e-11 43.3 6.5 4.3 6 0 0 6 6 6 2 GPCR proteolysis site, GPS, motif Pkinase_Tyr PF07714.17 PRP89789.1 - 4.6e-14 52.3 1.0 2.9e-07 30.0 0.1 3.8 2 2 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PRP89789.1 - 5.3e-13 48.9 0.1 1.1e-06 28.3 0.0 3.3 2 2 0 2 2 2 2 Protein kinase domain LRR_8 PF13855.6 PRP89789.1 - 5.5e-06 26.0 12.8 0.08 12.7 0.1 6.8 5 2 4 9 9 9 3 Leucine rich repeat LRR_4 PF12799.7 PRP89789.1 - 4.5e-05 23.7 13.1 5.2 7.6 0.0 6.9 7 1 1 8 8 8 3 Leucine Rich repeats (2 copies) EphA2_TM PF14575.6 PRP89789.1 - 0.011 16.6 0.1 5.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain LRRNT_2 PF08263.12 PRP89789.1 - 0.099 13.0 8.6 0.033 14.5 0.8 3.0 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain DUF2304 PF10066.9 PRP89789.1 - 1.6 9.0 4.4 56 4.0 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) LRR_1 PF00560.33 PRP89789.1 - 5.8 7.9 7.1 2.5e+02 2.9 0.1 5.6 5 1 1 6 6 6 0 Leucine Rich Repeat Crisp PF08562.10 PRP89789.1 - 6.3 7.5 10.8 12 6.6 1.6 3.1 2 0 0 2 2 2 0 Crisp Rab3-GTPase_cat PF13890.6 PRP89790.1 - 8.9e-47 158.8 0.3 8.9e-47 158.8 0.3 1.7 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit Asp PF00026.23 PRP89791.1 - 5.4e-119 397.3 0.8 7.2e-119 396.9 0.8 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PRP89791.1 - 1.9e-11 44.6 8.7 1.2e-10 41.9 3.2 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal SapB_2 PF03489.17 PRP89791.1 - 6.9e-09 35.7 1.2 1.8e-08 34.4 1.2 1.8 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.15 PRP89791.1 - 3.2e-07 30.2 0.2 3.2e-07 30.2 0.2 1.9 2 0 0 2 2 2 1 Saposin-like type B, region 1 Asp_protease_2 PF13650.6 PRP89791.1 - 0.00025 21.6 0.2 0.17 12.5 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 PRP89791.1 - 0.00034 20.4 0.0 0.00096 19.0 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 PRP89791.1 - 0.043 14.4 0.0 6.5 7.4 0.0 2.6 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF3456 PF11938.8 PRP89791.1 - 0.16 12.5 0.4 2.1 8.9 0.3 2.3 1 1 2 3 3 3 0 TLR4 regulator and MIR-interacting MSAP ABC1 PF03109.16 PRP89792.1 - 1.1e-28 99.8 0.0 2.7e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 ABC1 family DUF1442 PF07279.11 PRP89792.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) APH PF01636.23 PRP89792.1 - 0.14 12.0 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 PRP89792.1 - 0.18 11.4 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 RIO1 family DEAD PF00270.29 PRP89793.1 - 2.7e-42 144.5 0.2 5.2e-42 143.6 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PRP89793.1 - 4.4e-31 107.5 0.1 1.3e-28 99.5 0.0 3.1 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PRP89793.1 - 1.8e-09 37.8 0.1 3.9e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 PRP89793.1 - 4e-05 22.5 0.0 7.3e-05 21.6 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Rhomboid PF01694.22 PRP89794.1 - 2.3e-07 30.9 0.1 5.2e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Rhomboid family ZapB PF06005.12 PRP89795.1 - 0.0074 16.7 9.6 0.0074 16.7 9.6 15.0 4 3 7 11 11 11 1 Cell division protein ZapB Orn_Arg_deC_N PF02784.16 PRP89797.1 - 4.7e-70 235.8 0.0 6.3e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PRP89797.1 - 6.1e-19 68.1 0.0 1.4e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF3583 PF12126.8 PRP89797.1 - 0.019 14.5 0.1 0.026 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Pkinase_Tyr PF07714.17 PRP89798.1 - 1.5e-62 211.3 0.0 2.1e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89798.1 - 4.9e-49 167.1 0.0 7.2e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PRP89798.1 - 9.5e-47 156.6 72.6 4.5e-10 39.1 3.9 13.9 13 2 4 17 17 17 12 Leucine rich repeat LRR_4 PF12799.7 PRP89798.1 - 2e-37 126.6 67.6 0.00024 21.4 0.2 15.0 9 4 6 16 16 16 12 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PRP89798.1 - 5e-10 38.6 48.4 0.35 11.0 0.0 16.1 16 0 0 16 16 15 4 Leucine Rich repeat LRR_1 PF00560.33 PRP89798.1 - 7.2e-10 38.0 50.4 2.1 9.2 0.0 19.8 23 1 0 23 23 20 1 Leucine Rich Repeat Pkinase_fungal PF17667.1 PRP89798.1 - 0.0019 17.1 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Syndecan PF01034.20 PRP89798.1 - 0.02 14.8 5.0 0.045 13.7 5.0 1.6 1 0 0 1 1 1 0 Syndecan domain Kdo PF06293.14 PRP89798.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MINDY_DUB PF04424.13 PRP89798.1 - 0.086 12.9 0.1 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 MINDY deubiquitinase Amnionless PF14828.6 PRP89798.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Amnionless Gp58 PF07902.11 PRP89799.1 - 0.11 10.7 0.0 0.14 10.4 0.0 1.1 1 0 0 1 1 1 0 gp58-like protein ATP_synth_reg PF14960.6 PRP89799.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase regulation DUF4211 PF13926.6 PRP89800.1 - 5e-24 85.0 0.3 3.9e-23 82.1 0.0 2.6 1 1 0 2 2 2 1 Domain of unknown function (DUF4211) Rhomboid PF01694.22 PRP89801.1 - 4.2e-25 88.5 24.0 2.3e-15 56.9 8.8 2.5 2 0 0 2 2 2 2 Rhomboid family TPR_19 PF14559.6 PRP89801.1 - 5.9e-07 29.9 0.3 0.012 16.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Cohesin_HEAT PF12765.7 PRP89801.1 - 0.0015 18.8 0.3 0.23 11.8 0.1 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion TPR_2 PF07719.17 PRP89801.1 - 0.0025 17.8 0.8 1.5 9.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF1751 PF08551.10 PRP89801.1 - 2 9.0 4.9 15 6.2 0.9 2.7 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) EF-hand_7 PF13499.6 PRP89802.1 - 3.2e-14 53.1 0.2 8.8e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PRP89802.1 - 4.1e-12 44.7 0.2 3.1e-05 23.2 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PRP89802.1 - 5.2e-11 41.5 0.1 0.0004 20.1 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PRP89802.1 - 6.3e-11 41.9 0.1 8.9e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PRP89802.1 - 2e-07 30.2 0.3 0.00016 21.0 0.0 3.9 4 0 0 4 4 4 1 EF hand WH2 PF02205.20 PRP89803.1 - 8.9e-19 66.7 8.7 2.2e-10 40.0 1.1 2.8 2 0 0 2 2 2 2 WH2 motif LRR_8 PF13855.6 PRP89803.1 - 4.3e-10 39.2 11.8 1.3e-05 24.9 3.2 2.9 3 0 0 3 3 2 2 Leucine rich repeat GPS PF01825.21 PRP89803.1 - 5.9e-10 39.5 5.7 5.9e-10 39.5 5.7 2.1 2 0 0 2 2 1 1 GPCR proteolysis site, GPS, motif LRR_4 PF12799.7 PRP89803.1 - 9.4e-10 38.6 12.5 0.00014 22.2 1.9 5.3 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) SH3_1 PF00018.28 PRP89803.1 - 4e-09 36.0 0.1 1.2e-08 34.4 0.1 1.9 1 0 0 1 1 1 1 SH3 domain Pkinase_Tyr PF07714.17 PRP89803.1 - 9.5e-09 34.9 0.1 6.4e-08 32.2 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PRP89803.1 - 2.1e-08 33.9 0.0 4.8e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain DUF4772 PF15997.5 PRP89803.1 - 9e-05 23.1 0.0 0.74 10.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4772) SH3_9 PF14604.6 PRP89803.1 - 0.00074 19.3 0.2 0.00074 19.3 0.2 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 PRP89803.1 - 0.0032 17.1 0.0 0.0098 15.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PTS-HPr PF00381.19 PRP89803.1 - 0.13 12.5 0.1 18 5.6 0.0 2.4 2 0 0 2 2 2 0 PTS HPr component phosphorylation site EphA2_TM PF14575.6 PRP89803.1 - 0.14 13.0 0.1 0.38 11.7 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain UN_NPL4 PF11543.8 PRP89803.1 - 0.16 12.4 0.2 18 5.9 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Baculo_gp41 PF04700.12 PRP89803.1 - 0.35 10.6 2.4 0.86 9.4 2.4 1.6 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region LRR_1 PF00560.33 PRP89803.1 - 7.3 7.6 13.4 30 5.7 0.4 6.0 6 0 0 6 6 4 0 Leucine Rich Repeat TMEM154 PF15102.6 PRP89803.1 - 9.1 6.2 7.6 9.3 6.1 0.0 2.6 2 0 0 2 2 2 0 TMEM154 protein family ATP-grasp_2 PF08442.10 PRP89804.1 - 1.3e-69 233.8 0.8 1.3e-69 233.8 0.8 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 PRP89804.1 - 2.5e-27 95.6 0.7 5.1e-27 94.6 0.7 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 PRP89804.1 - 4e-12 46.1 0.1 7.3e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 PRP89804.1 - 0.0002 21.2 0.0 0.00067 19.5 0.0 1.8 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 PRP89804.1 - 0.0083 15.9 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Tsp45I PF06300.12 PRP89804.1 - 0.14 11.7 0.2 0.83 9.1 0.1 2.2 2 0 0 2 2 2 0 Tsp45I type II restriction enzyme Glyco_hydro_35 PF01301.19 PRP89805.1 - 1.5e-108 363.2 0.4 2.3e-108 362.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_transf_41 PF13844.6 PRP89805.1 - 4.4e-69 233.1 0.6 2e-36 125.5 1.4 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 Glyco_hydro_42 PF02449.15 PRP89805.1 - 8.3e-11 41.8 0.1 4.7e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 PRP89805.1 - 6.4e-10 39.6 2.4 1.3e-06 29.0 0.2 2.8 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain TPR_16 PF13432.6 PRP89805.1 - 0.0048 17.5 0.0 1.2 9.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PRP89805.1 - 0.0054 16.4 0.0 0.022 14.4 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 PRP89805.1 - 0.0091 16.0 0.2 0.72 10.1 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 PRP89805.1 - 0.018 14.8 0.2 0.33 10.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PRP89805.1 - 0.025 14.8 0.5 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RTA1 PF04479.13 PRP89806.1 - 1.3e-58 198.1 7.0 1.3e-58 198.1 7.0 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF5487 PF17589.2 PRP89806.1 - 0.039 14.2 0.2 0.085 13.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5487) Prominin PF05478.11 PRP89806.1 - 0.74 7.7 2.3 1.5 6.7 0.6 2.0 2 0 0 2 2 2 0 Prominin ZapB PF06005.12 PRP89809.1 - 0.00049 20.5 10.2 0.00049 20.5 10.2 3.3 3 0 0 3 3 3 1 Cell division protein ZapB APH PF01636.23 PRP89809.1 - 0.0087 16.0 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family CENP-Q PF13094.6 PRP89809.1 - 0.031 14.5 15.3 0.053 13.7 4.1 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SBF PF01758.16 PRP89814.1 - 0.04 13.6 0.4 0.044 13.4 0.4 1.0 1 0 0 1 1 1 0 Sodium Bile acid symporter family SASA PF03629.18 PRP89815.1 - 2.8e-16 59.9 0.0 1.2e-15 57.7 0.0 2.0 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase Yip1 PF04893.17 PRP89816.1 - 2.5e-12 46.9 13.6 2.8e-12 46.7 12.3 1.6 1 1 1 2 2 2 1 Yip1 domain RSN1_7TM PF02714.15 PRP89817.1 - 9e-60 202.3 26.0 2e-59 201.1 26.0 1.6 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PRP89817.1 - 1.5e-19 70.3 6.2 1.5e-19 70.3 6.2 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PRP89817.1 - 6.9e-13 49.2 1.2 2.1e-07 31.4 1.2 2.8 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Parvo_coat PF00740.18 PRP89817.1 - 0.029 13.0 0.1 0.044 12.4 0.1 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 EF-hand_like PF09279.11 PRP89817.1 - 0.081 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like 7TM_GPCR_Srw PF10324.9 PRP89817.1 - 0.57 9.4 16.9 0.39 10.0 8.5 2.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF2721 PF11026.8 PRP89817.1 - 3.5 7.5 9.7 20 5.1 5.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) PIG-F PF06699.11 PRP89820.1 - 1.3 9.1 8.6 0.13 12.4 3.7 1.7 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F GAF PF01590.26 PRP89821.1 - 2.3e-07 31.5 0.0 3.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PRP89821.1 - 1.6e-06 28.5 0.0 2.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 PRP89821.1 - 1.6e-06 28.5 0.0 2.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain RasGEF PF00617.19 PRP89822.1 - 7.2e-34 117.5 0.2 1.5e-33 116.5 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 PRP89822.1 - 1.5e-08 34.8 2.2 7.2e-07 29.4 0.8 2.9 2 1 0 2 2 2 1 RasGEF N-terminal motif IQ PF00612.27 PRP89822.1 - 2.7e-06 26.7 0.5 2.7e-06 26.7 0.5 3.0 3 0 0 3 3 3 1 IQ calmodulin-binding motif DnaJ PF00226.31 PRP89823.1 - 6.4e-16 58.2 0.2 1.4e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain HMG-CoA_red PF00368.18 PRP89825.1 - 1.1e-139 465.6 2.1 2.3e-139 464.5 2.1 1.6 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF3074 PF11274.8 PRP89825.1 - 0.15 12.0 6.0 0.39 10.7 4.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3074) Erp_C PF06780.11 PRP89825.1 - 0.16 12.0 0.2 5 7.1 0.0 2.7 3 0 0 3 3 3 0 Erp protein C-terminus Pkinase PF00069.25 PRP89826.1 - 3.2e-49 167.7 0.1 7.2e-49 166.5 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Med23 PF11573.8 PRP89826.1 - 3.4e-33 114.5 16.1 3.5e-23 81.3 6.2 2.5 2 1 0 2 2 2 2 Mediator complex subunit 23 Pkinase_Tyr PF07714.17 PRP89826.1 - 1.5e-30 106.4 0.0 2.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PRP89826.1 - 0.018 13.8 0.1 0.035 12.9 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF3375 PF11855.8 PRP89826.1 - 0.065 12.1 0.2 0.42 9.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) DUF3915 PF13054.6 PRP89827.1 - 0.063 13.3 4.6 0.076 13.0 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Phage_Gp23 PF10669.9 PRP89827.1 - 0.13 12.6 3.3 0.15 12.4 3.3 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Atrophin-1 PF03154.15 PRP89827.1 - 0.41 8.9 8.9 0.38 9.0 8.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF1509 PF07420.11 PRP89827.1 - 0.5 9.3 6.0 0.55 9.1 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) RGS PF00615.19 PRP89828.1 - 1.7e-19 70.3 3.8 1.7e-19 70.3 3.8 3.0 2 1 0 2 2 2 1 Regulator of G protein signaling domain RRXRR PF14239.6 PRP89828.1 - 0.49 10.2 14.2 0.79 9.6 12.2 2.4 2 0 0 2 2 2 0 RRXRR protein AOX PF01786.17 PRP89829.1 - 7.7e-62 208.7 0.6 1.4e-61 207.8 0.6 1.3 1 1 0 1 1 1 1 Alternative oxidase V-SNARE_C PF12352.8 PRP89830.1 - 0.0017 18.6 8.5 0.002 18.4 5.7 2.6 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Grg1 PF11034.8 PRP89831.1 - 3.8e-09 36.7 4.5 6e-09 36.0 4.5 1.3 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 LRR_4 PF12799.7 PRP89832.1 - 2.7e-36 122.9 51.6 0.0001 22.6 0.6 9.8 6 3 1 9 9 9 8 Leucine Rich repeats (2 copies) Patatin PF01734.22 PRP89832.1 - 3.8e-28 99.1 0.1 6.1e-28 98.4 0.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase LRR_8 PF13855.6 PRP89832.1 - 1.2e-27 95.4 54.9 2.8e-08 33.4 1.2 9.0 6 2 1 8 8 8 7 Leucine rich repeat LRR_6 PF13516.6 PRP89832.1 - 0.011 15.7 54.6 6.5 7.1 0.4 13.9 14 0 0 14 14 14 0 Leucine Rich repeat LRR_1 PF00560.33 PRP89832.1 - 0.029 14.9 44.7 11 7.0 0.0 13.4 12 2 0 12 12 12 0 Leucine Rich Repeat ATP-synt_F6 PF05511.11 PRP89832.1 - 0.16 12.4 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 TPR_2 PF07719.17 PRP89833.1 - 0.12 12.5 0.4 0.34 11.1 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat C2-C2_1 PF11618.8 PRP89833.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 UPF0561 PF10573.9 PRP89833.1 - 4.2 7.5 6.5 2.1 8.5 2.2 2.6 2 1 1 3 3 3 0 Uncharacterised protein family UPF0561 Pro-kuma_activ PF09286.11 PRP89835.1 - 2.3e-25 89.5 0.1 6.5e-25 88.1 0.1 1.8 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 PRP89835.1 - 0.08 12.2 1.4 0.19 11.0 1.4 1.7 1 1 0 1 1 1 0 Subtilase family Cadherin_C_2 PF16492.5 PRP89835.1 - 0.25 12.1 0.9 0.59 10.9 0.9 1.6 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Pkinase PF00069.25 PRP89838.1 - 1.4e-52 178.7 0.0 3.2e-35 121.8 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PRP89838.1 - 9.1e-31 107.1 0.0 1.5e-21 76.9 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 PRP89838.1 - 2e-06 27.6 0.1 0.022 14.4 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PRP89838.1 - 0.0048 16.2 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PRP89838.1 - 0.047 12.5 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PRP89838.1 - 0.088 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PRP89838.1 - 0.12 12.3 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family PH_3 PF14593.6 PRP89839.1 - 0.016 15.3 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 PH domain FAD_binding_2 PF00890.24 PRP89840.1 - 1.1e-74 252.0 0.1 1.7e-74 251.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain LRR_8 PF13855.6 PRP89840.1 - 2.7e-48 161.5 51.3 1.1e-10 41.1 6.6 9.8 6 1 3 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 PRP89840.1 - 1.4e-30 104.8 54.8 0.00054 20.3 3.1 11.7 4 3 7 13 13 13 12 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 PRP89840.1 - 1.3e-23 83.6 1.8 7.8e-23 81.1 1.8 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Cyt-b5 PF00173.28 PRP89840.1 - 3.2e-22 78.5 0.0 7.5e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pkinase PF00069.25 PRP89840.1 - 8.9e-15 54.8 0.3 2.3e-14 53.4 0.3 1.7 1 1 0 1 1 1 1 Protein kinase domain DAO PF01266.24 PRP89840.1 - 5.1e-12 46.0 0.0 1.2e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PRP89840.1 - 3.3e-09 36.6 0.2 6.8e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase LRR_1 PF00560.33 PRP89840.1 - 1.8e-08 33.7 52.3 0.27 11.9 0.1 15.7 18 2 2 20 20 15 3 Leucine Rich Repeat NAD_binding_8 PF13450.6 PRP89840.1 - 4.2e-08 33.3 0.4 1.3e-07 31.7 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GPS PF01825.21 PRP89840.1 - 9.2e-08 32.5 0.1 1.9e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif HI0933_like PF03486.14 PRP89840.1 - 1.1e-06 27.6 1.3 0.00072 18.4 0.4 2.5 2 1 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 PRP89840.1 - 2.7e-06 26.8 0.4 9.5e-06 25.0 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase LRR_6 PF13516.6 PRP89840.1 - 8.4e-06 25.4 30.4 0.094 12.8 0.3 10.4 11 0 0 11 11 10 2 Leucine Rich repeat Pyr_redox_3 PF13738.6 PRP89840.1 - 5.6e-05 22.5 0.1 0.065 12.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PRP89840.1 - 0.0012 18.1 0.1 0.0023 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain SCAB_CC PF16712.5 PRP89840.1 - 0.004 17.0 1.4 0.0078 16.1 1.4 1.4 1 0 0 1 1 1 1 Coiled-coil regions of plant-specific actin-binding protein GIDA PF01134.22 PRP89840.1 - 0.0058 15.8 5.4 0.044 12.9 0.2 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 PRP89840.1 - 0.0058 15.9 1.2 0.015 14.6 0.3 2.0 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 PRP89840.1 - 0.029 13.6 0.6 0.067 12.5 0.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 PRP89840.1 - 0.04 13.2 0.5 0.35 10.1 0.3 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 PRP89840.1 - 0.068 13.7 1.8 0.24 12.0 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PRP89840.1 - 0.16 11.9 0.0 0.55 10.2 0.0 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding LRR_12 PF18837.1 PRP89840.1 - 3.8 7.3 12.4 0.28 10.9 0.2 4.0 5 0 0 5 5 5 0 Leucine-rich repeat RCC1 PF00415.18 PRP89841.1 - 5.6e-49 164.5 5.9 1.4e-09 38.4 0.1 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PRP89841.1 - 6.8e-18 64.0 34.0 5.4e-05 22.9 1.4 7.8 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Orexin_rec2 PF03827.13 PRP89841.1 - 0.14 12.2 0.3 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 Orexin receptor type 2 B_lectin PF01453.24 PRP89842.1 - 2e-06 28.3 0.0 0.0073 16.8 0.0 2.5 1 1 2 3 3 3 3 D-mannose binding lectin KRTAP PF11759.8 PRP89842.1 - 3.5 8.3 20.9 13 6.5 20.9 2.0 1 1 0 1 1 1 0 Keratin-associated matrix Ribosomal_L30 PF00327.20 PRP89843.1 - 0.11 12.5 0.0 5 7.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e DUF1996 PF09362.10 PRP89844.1 - 3e-61 207.4 0.1 4.3e-61 206.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Fascin PF06268.13 PRP89844.1 - 1.4e-08 34.9 0.9 0.0069 16.6 0.0 3.2 2 1 1 3 3 3 3 Fascin domain FGF PF00167.18 PRP89844.1 - 0.079 13.1 0.5 37 4.4 0.0 3.3 3 1 1 4 4 4 0 Fibroblast growth factor PD40 PF07676.12 PRP89844.1 - 0.18 11.8 6.2 9.4 6.3 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RicinB_lectin_2 PF14200.6 PRP89844.1 - 0.24 12.1 13.2 5.3 7.8 0.8 3.8 2 2 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like HEAT PF02985.22 PRP89845.1 - 0.0066 16.6 0.6 47 4.6 0.0 5.3 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 PRP89845.1 - 0.018 15.1 0.1 7.5 6.8 0.0 4.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ubiquitin PF00240.23 PRP89846.1 - 0.16 11.8 0.5 1.4 8.8 0.2 2.4 2 1 0 2 2 2 0 Ubiquitin family CAAP1 PF15335.6 PRP89847.1 - 0.01 16.3 0.0 1.1e+02 3.4 0.0 5.7 5 1 1 6 6 6 0 Caspase activity and apoptosis inhibitor 1 DUF1664 PF07889.12 PRP89848.1 - 0.0019 18.2 9.6 1.3 9.1 1.9 4.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 PRP89848.1 - 0.024 14.5 10.3 69 3.2 0.0 3.6 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3453 PF11935.8 PRP89848.1 - 0.026 14.2 0.1 0.069 12.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Spc7 PF08317.11 PRP89848.1 - 0.032 13.1 12.6 0.045 12.6 5.4 3.1 1 1 1 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 PRP89848.1 - 0.033 14.7 9.5 0.79 10.2 0.2 4.6 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Sipho_Gp157 PF05565.11 PRP89848.1 - 0.041 13.9 3.7 0.71 9.9 0.0 3.3 2 2 1 3 3 3 0 Siphovirus Gp157 Med9 PF07544.13 PRP89848.1 - 0.045 13.8 5.8 0.45 10.6 0.1 4.2 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.12 PRP89848.1 - 0.054 13.5 12.7 0.7 9.9 0.1 3.7 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Gon7 PF08738.10 PRP89848.1 - 0.1 12.7 0.5 0.43 10.7 0.5 2.1 1 0 0 1 1 1 0 Gon7 family DUF3053 PF11254.8 PRP89848.1 - 0.11 12.1 1.8 4 7.0 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3053) EzrA PF06160.12 PRP89848.1 - 0.12 10.5 8.9 0.34 9.0 6.9 2.5 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF2203 PF09969.9 PRP89848.1 - 0.14 12.9 4.9 16 6.2 0.0 3.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 PRP89848.1 - 0.16 12.1 8.1 9.3 6.4 0.2 3.7 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 PRP89848.1 - 0.22 11.5 9.5 1.2 9.1 0.1 3.5 1 1 0 3 3 3 0 Laminin Domain II TACC_C PF05010.14 PRP89848.1 - 0.25 11.1 7.4 0.2 11.4 0.6 3.1 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2408 PF10303.9 PRP89848.1 - 0.36 11.4 10.6 3.3 8.3 6.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.12 PRP89848.1 - 0.52 10.4 10.8 0.11 12.5 3.6 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein RCSD PF05177.12 PRP89848.1 - 1 10.3 6.5 52 4.8 6.1 2.4 1 1 1 2 2 2 0 RCSD region COG5 PF10392.9 PRP89848.1 - 1.2 9.3 9.1 21 5.3 0.2 3.7 3 1 0 3 3 3 0 Golgi transport complex subunit 5 DHR10 PF18595.1 PRP89848.1 - 1.5 8.9 10.6 3.6 7.7 0.3 3.1 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain WXG100 PF06013.12 PRP89848.1 - 1.6 9.0 6.6 15 5.9 0.1 3.9 3 2 1 3 3 2 0 Proteins of 100 residues with WXG DUF713 PF05218.14 PRP89848.1 - 1.8 8.3 8.6 1.8 8.3 0.6 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF713) DUF16 PF01519.16 PRP89848.1 - 1.9 9.1 6.0 23 5.5 4.1 3.2 2 1 0 2 2 1 0 Protein of unknown function DUF16 FUSC PF04632.12 PRP89848.1 - 2.1 6.8 9.7 0.59 8.6 6.2 1.7 1 1 0 2 2 2 0 Fusaric acid resistance protein family CorA PF01544.18 PRP89848.1 - 2.6 7.3 15.8 0.44 9.8 3.0 3.2 1 1 1 3 3 3 0 CorA-like Mg2+ transporter protein Spot_14 PF07084.12 PRP89848.1 - 2.8 8.1 5.8 8.4 6.5 0.2 2.8 2 1 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 ABC_tran_CTD PF16326.5 PRP89848.1 - 3 8.2 6.6 3.6 7.9 0.0 3.8 2 1 2 4 4 4 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 PRP89848.1 - 6.4 7.1 7.8 12 6.2 2.3 3.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 PRP89848.1 - 8.7 6.7 7.5 12 6.2 0.0 4.4 3 1 1 4 4 3 0 Homeobox associated leucine zipper Hydrolase_4 PF12146.8 PRP89849.1 - 8.5e-12 44.8 0.0 6.3e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PRP89849.1 - 5.6e-07 29.3 0.0 9.6e-06 25.2 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 PRP89849.1 - 0.0004 20.3 0.0 0.14 12.0 0.0 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 PRP89849.1 - 0.0013 18.4 0.1 0.19 11.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 PRP89849.1 - 0.0042 16.8 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 PRP89849.1 - 0.024 14.2 0.0 0.051 13.1 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family UMPH-1 PF05822.12 PRP89849.1 - 0.056 13.0 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Abhydrolase_3 PF07859.13 PRP89849.1 - 0.076 12.9 0.0 0.69 9.7 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PRP89850.1 - 1e-28 101.4 0.0 1.3e-28 101.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PRP89850.1 - 4.5e-14 52.3 0.0 7.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PRP89850.1 - 6.1e-12 45.7 0.0 1.4e-11 44.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 PRP89850.1 - 5.1e-05 23.1 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 PRP89850.1 - 0.00019 21.3 0.0 0.00043 20.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 PRP89850.1 - 0.00025 20.9 0.6 0.42 10.4 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 PRP89850.1 - 0.00032 20.6 0.0 0.0005 20.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 PRP89850.1 - 0.0016 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DLH PF01738.18 PRP89850.1 - 0.0036 16.9 0.0 0.013 15.0 0.1 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Palm_thioest PF02089.15 PRP89850.1 - 0.0038 17.1 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 PRP89850.1 - 0.0059 16.5 0.4 0.012 15.5 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 PRP89850.1 - 0.0092 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF676 PF05057.14 PRP89850.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 PRP89850.1 - 0.0094 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 PRP89850.1 - 0.0099 16.0 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 PRP89850.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_2 PF01674.18 PRP89850.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Ser_hydrolase PF06821.13 PRP89850.1 - 0.025 14.5 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Cutinase PF01083.22 PRP89850.1 - 0.029 14.4 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase LCAT PF02450.15 PRP89850.1 - 0.039 13.1 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UPF0227 PF05728.12 PRP89850.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.11 PRP89850.1 - 0.13 12.2 0.0 3 7.7 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal F-box-like PF12937.7 PRP89851.1 - 0.00025 20.9 1.2 0.0009 19.1 0.2 2.5 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 PRP89851.1 - 0.0015 18.4 1.7 0.15 12.2 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeat F-box PF00646.33 PRP89851.1 - 0.061 13.2 0.1 0.061 13.2 0.1 3.1 4 0 0 4 4 4 0 F-box domain Baculo_p74 PF04583.12 PRP89851.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Baculoviridae p74 conserved region Imm41 PF15592.6 PRP89851.1 - 0.071 13.5 0.2 0.22 11.9 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 41 LRR_8 PF13855.6 PRP89851.1 - 4 7.3 6.3 4.4 7.2 1.3 3.6 3 1 0 3 3 3 0 Leucine rich repeat AAA_6 PF12774.7 PRP89853.1 - 2.7e-151 503.2 0.0 1.4e-147 490.9 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PRP89853.1 - 1.1e-112 377.1 11.5 1.1e-112 377.1 11.5 2.7 3 0 0 3 3 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 PRP89853.1 - 6.9e-102 340.8 0.1 2.5e-101 338.9 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 PRP89853.1 - 5.5e-96 320.9 0.1 2.5e-95 318.7 0.0 2.3 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 PRP89853.1 - 2.3e-78 262.3 0.4 2.3e-78 262.3 0.4 5.4 5 0 0 5 5 5 1 ATP-binding dynein motor region AAA_7 PF12775.7 PRP89853.1 - 6.4e-70 234.3 2.1 4e-66 222.0 0.0 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 PRP89853.1 - 1.7e-52 178.6 7.2 2.9e-52 177.8 7.2 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PRP89853.1 - 2.7e-52 176.9 0.0 2.9e-51 173.5 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PRP89853.1 - 9.7e-42 141.8 0.0 6.2e-39 132.8 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PRP89853.1 - 8.6e-27 93.8 0.0 7.7e-26 90.7 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PRP89853.1 - 1.6e-19 70.0 0.0 6.6e-19 68.0 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PRP89853.1 - 8.5e-18 64.7 0.0 2.4e-05 24.4 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.29 PRP89853.1 - 2.8e-09 37.5 0.1 0.0088 16.5 0.0 4.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PRP89853.1 - 1.2e-07 32.2 0.6 0.0056 17.1 0.0 5.2 5 0 0 5 5 4 1 AAA ATPase domain AAA_22 PF13401.6 PRP89853.1 - 0.0001 22.6 2.0 0.4 11.0 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA_18 PF13238.6 PRP89853.1 - 0.00012 22.7 0.0 0.77 10.3 0.0 4.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 PRP89853.1 - 0.0002 21.7 0.1 4.3 7.8 0.0 4.4 4 0 0 4 4 3 1 RNA helicase DUF815 PF05673.13 PRP89853.1 - 0.00032 19.9 0.0 0.15 11.2 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 PRP89853.1 - 0.00079 19.1 0.1 0.018 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PRP89853.1 - 0.0011 19.3 0.0 0.14 12.5 0.0 3.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 PRP89853.1 - 0.0019 18.0 0.0 0.025 14.3 0.0 3.1 4 0 0 4 4 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 PRP89853.1 - 0.0025 17.6 0.1 3 7.5 0.2 2.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 PRP89853.1 - 0.003 16.9 0.1 0.02 14.3 0.0 2.5 2 0 0 2 2 2 1 KaiC ABC_tran PF00005.27 PRP89853.1 - 0.0049 17.4 0.0 3.2 8.3 0.0 3.5 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.26 PRP89853.1 - 0.0075 16.0 0.6 0.58 9.8 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain T2SSE PF00437.20 PRP89853.1 - 0.012 14.6 1.3 0.038 13.0 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein ResIII PF04851.15 PRP89853.1 - 0.019 15.0 0.3 0.21 11.6 0.0 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 PRP89853.1 - 0.019 15.0 0.0 0.21 11.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 PRP89853.1 - 0.035 13.8 0.0 11 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PRP89853.1 - 0.052 13.3 0.3 3.7 7.4 0.0 2.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain NACHT PF05729.12 PRP89853.1 - 0.11 12.4 0.1 9.8 6.1 0.0 3.7 3 0 0 3 3 3 0 NACHT domain Roc PF08477.13 PRP89853.1 - 0.13 12.5 0.1 22 5.3 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 PRP89853.1 - 0.14 12.2 1.8 3.6 7.6 0.0 3.4 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 PRP89853.1 - 0.14 11.5 1.6 4.2 6.7 0.0 3.1 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 PRP89853.1 - 0.43 9.9 5.1 9.9 5.4 0.1 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family UvrD-helicase PF00580.21 PRP89853.1 - 0.51 9.8 0.0 0.51 9.8 0.0 3.6 3 1 0 3 3 2 0 UvrD/REP helicase N-terminal domain IFT20 PF14931.6 PRP89855.1 - 1.2e-34 119.0 12.9 2.8e-34 117.9 12.9 1.6 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 MSC PF09402.10 PRP89855.1 - 8.4e-22 78.1 1.6 8.4e-22 78.1 1.6 3.5 3 1 1 4 4 4 1 Man1-Src1p-C-terminal domain DUF2207 PF09972.9 PRP89855.1 - 0.01 14.6 0.0 0.11 11.3 0.0 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) HeH PF12949.7 PRP89855.1 - 0.042 13.6 0.2 0.042 13.6 0.2 1.9 2 0 0 2 2 2 0 HeH/LEM domain DUF3262 PF11660.8 PRP89855.1 - 0.056 13.8 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Xan_ur_permease PF00860.20 PRP89855.1 - 0.25 10.0 1.6 0.4 9.3 1.6 1.2 1 0 0 1 1 1 0 Permease family EGF_MSP1_1 PF12946.7 PRP89855.1 - 0.47 10.6 4.3 0.37 10.9 2.4 1.8 2 0 0 2 2 2 0 MSP1 EGF domain 1 Acetate_kinase PF00871.17 PRP89856.1 - 3.1e-124 414.6 0.5 3.9e-124 414.3 0.5 1.0 1 0 0 1 1 1 1 Acetokinase family ECH_2 PF16113.5 PRP89856.1 - 0.057 12.9 0.4 0.094 12.2 0.4 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase GCP_C_terminal PF04130.13 PRP89857.1 - 2.6e-44 152.0 5.3 5.2e-44 151.0 5.3 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PRP89857.1 - 1.1e-07 31.8 0.1 6.1e-05 22.8 0.0 3.8 2 2 1 3 3 3 2 Gamma tubulin complex component N-terminal Mur_ligase_M PF08245.12 PRP89859.1 - 4.8e-07 30.0 0.0 6.6e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 PRP89859.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain PARP PF00644.20 PRP89860.1 - 3.4e-12 46.4 1.6 3.4e-12 46.4 1.6 1.7 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain SUZ PF12752.7 PRP89860.1 - 6.7e-10 39.6 0.3 2.5e-09 37.7 0.3 2.1 1 0 0 1 1 1 1 SUZ domain TFIIA PF03153.13 PRP89861.1 - 8.9e-12 45.7 0.5 5.5e-05 23.3 0.0 2.4 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Avl9 PF09794.9 PRP89861.1 - 0.16 10.6 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 Glyco_hydro_38N PF01074.22 PRP89862.1 - 7.9e-78 261.7 10.9 1.2e-77 261.2 10.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PRP89862.1 - 3.2e-26 92.7 0.1 8.1e-20 71.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal domain zf-C2HC_2 PF13913.6 PRP89862.1 - 4.8e-20 71.0 21.9 5.5e-08 32.5 2.6 3.4 3 0 0 3 3 3 3 zinc-finger of a C2HC-type Alpha-mann_mid PF09261.11 PRP89862.1 - 5e-10 39.4 0.1 1.2e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PRP89862.1 - 9.3e-09 35.3 0.0 2.7e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain zf-C2H2_4 PF13894.6 PRP89862.1 - 0.045 14.6 7.4 3.3 8.8 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 PRP89862.1 - 0.078 13.5 4.5 7 7.3 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 PRP89862.1 - 2.3 7.8 3.6 15 5.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain FYVE PF01363.21 PRP89862.1 - 3.4 7.9 7.5 26 5.0 0.0 3.2 3 0 0 3 3 3 0 FYVE zinc finger DUF2256 PF10013.9 PRP89862.1 - 9.2 6.5 7.5 16 5.7 0.2 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn-ribbon_8 PF09723.10 PRP89862.1 - 9.6 6.4 8.9 4.8 7.4 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain RNase_P_p30 PF01876.16 PRP89863.1 - 2.7e-41 141.4 0.0 3.4e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Lipase_3 PF01764.25 PRP89864.1 - 9.9e-35 119.5 0.0 1.5e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 PRP89864.1 - 0.00089 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 PRP89864.1 - 0.0015 18.2 0.0 0.0038 16.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 PRP89864.1 - 0.0064 17.1 0.0 0.01 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 PRP89864.1 - 0.011 15.9 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 PRP89864.1 - 0.081 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 PRP89864.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Ribonuc_red_lgC PF02867.15 PRP89866.1 - 3.3e-186 619.9 0.0 4e-186 619.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 PRP89866.1 - 9.6e-26 89.6 0.0 2.3e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 PRP89866.1 - 1.6e-11 44.6 0.0 4.5e-11 43.2 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain UQ_con PF00179.26 PRP89867.1 - 1.3e-14 54.1 0.0 2.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Exonuc_VII_L PF02601.15 PRP89868.1 - 1.7 8.1 7.1 2.6 7.5 7.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mito_carr PF00153.27 PRP89869.1 - 1.5e-62 207.5 0.3 4.1e-25 87.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Planoprotostelium_fungivorum-ASM302417v1/GCA_003024175.1_ASM302417v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Planoprotostelium_fungivorum-ASM302417v1/GCA_003024175.1_ASM302417v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Planoprotostelium_fungivorum-ASM302417v1/GCA_003024175.1_ASM302417v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Planoprotostelium_fungivorum-ASM302417v1/GCA_003024175.1_ASM302417v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 11:18:30 2019 # [ok]